LOCUS       DAPDIM010000001       101584 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000001 DAPDIM010000000
VERSION     DAPDIM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 101584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 101584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..101584
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.001"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(192..1553)
                     /locus_tag="RFE25_000001"
     CDS             complement(192..1553)
                     /locus_tag="RFE25_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDU2815115.1"
                     /translation="MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILL
                     TYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGM
                     AEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIG
                     LIVVGFVMILFAFKTQFGHASFTNLYEHGIFAKGASGFFMSFQMALFSFVGIEMIGVT
                     AGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGI
                     PFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFA
                     SSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKNA
                     TYKLLGGKYMGYLIFVFFIFVFGLLFINVDTRRAIYFIPIWFILLAFMYLRYKRIAAK
                     SNK"
     gene            1901..3022
                     /locus_tag="RFE25_000002"
     CDS             1901..3022
                     /locus_tag="RFE25_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001662816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HDU2815116.1"
                     /translation="MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEE
                     VIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYI
                     AHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYM
                     LRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPL
                     HGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSR
                     QITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSR
                     SAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK"
     gene            3071..4339
                     /gene="icd"
                     /locus_tag="RFE25_000003"
     CDS             3071..4339
                     /gene="icd"
                     /locus_tag="RFE25_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HDU2815117.1"
                     /translation="MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAA
                     VEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIR
                     SLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTT
                     EVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLV
                     HKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVENEGRDAANAAQEKAEKEG
                     KIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYE
                     TGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASK
                     VVTYDFARLMDGAEEVSTSAFADELIKNLK"
     gene            4729..5433
                     /locus_tag="RFE25_000004"
     CDS             4729..5433
                     /locus_tag="RFE25_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2815118.1"
                     /translation="MSQKVLVVDDEHSIVTLLKYNLETAGYEVVVAFDGDEALEKVES
                     EQPDLIILDVMLPKKDGIDVCKTVRTNKNLVPILMLTAKNDEFDRVLGLELGADDYMT
                     KPFSPREVVARVKAILRRSQFVKEVEEIDDDITIGSIRIRPDYFEVYKHNELLELTPK
                     EFELLLYLIERQGRVITREHMLNTVWNYEFAGDSRIVDVHISHLRDKLEDNPKKPQLI
                     KTVRGLGYKLERPKEQ"
     gene            5433..7094
                     /locus_tag="RFE25_000005"
     CDS             5433..7094
                     /locus_tag="RFE25_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HDU2815119.1"
                     /translation="MKFHHRLMLLISSILIISFVTLGIIIHASITYVLSEKHEQALAT
                     DARSYIYLVQDNEIDKVKEIVKQQNIDLLITKHDKKVFSSGKLKAIPNSDSYIQKRDV
                     FIFNKKVNGYHVWIKGYNNDITEMHWTLWKYLILTCLVVLICLYFASRSFKRTLIRPI
                     QEVTYATQLLANGYYHIRVPESNVVETKALFVSTNDLARRLQKLNNEQKIQSNRLKTT
                     IENIPSAILMIDRNGKIVVANKAYYEQFNISHNIEQVGYHGYVNTEIEQLILESFKVE
                     KPIYEQLEVAINQVHAKYFDISCVPILTRSQKSLQGILVVMHDITNLKQLENLRREFV
                     ANVSHELKTPITSIKGFAETLIDGAKNDAESLDMFLNIILKESNRIESLVTDLLDLSH
                     IEQHTELDTDYMNLSDLTRRIIDNMMTQANQKNISIHTDIEKDVIVKAQESKIAQVIT
                     NLLTNAINYSYEDGDINVRVYRDDFRVIFEVQDFGIGIKLEDQQRIFERFYRVDKARS
                     RDSGGTGLGLSITKHIVEAHQGNIEVNSQVGKGSTFKVILKDYKE"
     gene            7593..9080
                     /locus_tag="RFE25_000006"
     CDS             7593..9080
                     /locus_tag="RFE25_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815120.1"
                     /translation="MKTIQLHKTTLILIAILLFYTFMGILLPIMHDDLQWFSNYNTDI
                     LKVGFASLNGRYIGNIFEIIAVHVSWLRWLSYGLISMGIIWMIMHITRCKAWTSYYLL
                     AFSLMLILPSAIYADTYGWFAGFYNYATSTLISLFIIYYCINAIIYKEKQPVSVTVLF
                     YVLCFFGQLFMENVTLFHCIILILAFLYEFTANRTLNYKLLFSFMIATIGTIIMFSNP
                     NYRKILFEGSEYQQVSNNQGIFSKFAEMISTSLPYGVIFSQIIILSMIAALIIYLLLR
                     SDRYVHLTILKRRIIMIGFITLPLYYLLFYNQFLLNKNTDIGLVGFVNVIVCGYFAFS
                     IFVGIYLSINDRKTQITLYSLLIAICVSASTLVIVTPIEPGNFLIVYTIHVIILIILL
                     KEFRKYKSINVNFIKGASLVLAVIYLSAFIYVHYEHEKRVQLLKQQIKDHPRQEVYTV
                     ESLPFEHYMHHPSPINKNYQEWFNNYEELPKMTKVKYIPFGSDDS"
     gene            9374..12004
                     /gene="polA"
                     /locus_tag="RFE25_000007"
     CDS             9374..12004
                     /gene="polA"
                     /locus_tag="RFE25_000007"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDU2815121.1"
                     /translation="MNKLVLIDGNSLSFRAFYALPLLSNKAGIHTNAVYGFAMLLEKI
                     LKEEKPNHFLVAFDAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRY
                     ELDNYEADDIIGTLSKEADKAGFQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYT
                     PDFIAEKYNGLTPNQIIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHL
                     DEISGKKLKEKLQNSKEDALMSKELATINVDSPIEVKLEDTLMTHQDEQQEKIELFKK
                     LEFKQLLSDIDQSASVEDAIEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNIL
                     KFSLFTGEKHIVINADDINNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNIS
                     FDIMLASYIIDPSRTISDVQSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVAS
                     ITDAIYFAKPNMDKQLEEYNQVELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEI
                     QEKLDVLIRNIHDAAGEDFNINSPKQLGVVLFETLQLPVIKKTKTGYSTAVDVLEQLQ
                     GEHPIIDYILEYRQLSKLQSTYVEGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQ
                     NIPVRLEEGRKIRKAFKPTSKDSVILSADYSQIELRVLAHITQDESMKEAFINGDDIH
                     TATAMKVFGVEADQVDSLMRRQAKAVNFGIVYGISDYGLSQSLGITRKKAKAFIDDYL
                     ASFPGVKQYMSDIVKDAKALGYVETLLHRRRYIPDITSRNFNLRGFAERTAMNTPIQG
                     SAADIIKLAMVKFAQKMKETTYQAKLLLQVHDELIFEVPKSEVDSFSEFVEEIMENAL
                     QLDVPLKVDSSYGATWYDAK"
     gene            12020..12892
                     /gene="mutM"
                     /locus_tag="RFE25_000008"
     CDS             12020..12892
                     /gene="mutM"
                     /locus_tag="RFE25_000008"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HDU2815122.1"
                     /translation="MPELPEVEHVKRGIEPYVINQKIEHVIFSDKVIEGKAQGKETII
                     KGIELDTFKTLSEGYTITNVERRSKYIVFQLDNKREQRTLISHLGMAGGFFIVDELED
                     IMIPNYRKHWHVIFELSNDKKLIYSDIRRFGEIRNVASVASYPSFLEIAPEPFTNEAL
                     TYYLNRIHQQSNKNKPIKQVILDHKVIAGCGNIYACEALFRAGVLPDKKVKDLTHQQQ
                     EMVFYYVREVLEEGIKHGGTSISDYRHADGKTGEMQLHLNVYKQPVCKVCGSQIETKI
                     IATRNSHYCPVCQK"
     gene            12908..13531
                     /locus_tag="RFE25_000009"
     CDS             12908..13531
                     /locus_tag="RFE25_000009"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDU2815123.1"
                     /translation="MPKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGS
                     KGLAQVREVFGDEAIDENGEMNRRYMGDLVFNHPEKRLELNAIIHPIVRDIMEEEKQE
                     YLKQGYNVIMDIPLLFENELENTVDEVWVVYTSESIQMDRLMQRNNLSLEDAKARVYS
                     QISIDKKSRMADHVIDNLGDKLELKQNLERLLEEEGYIEKPNYGEED"
     gene            13701..14726
                     /gene="gap"
                     /locus_tag="RFE25_000010"
     CDS             13701..14726
                     /gene="gap"
                     /locus_tag="RFE25_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDU2815124.1"
                     /translation="MSTNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHL
                     INYDTTHGKYNLKVEPIENGLQVGDHKIKLVADRNPENLPWKELDIDIAIDATGKFNH
                     GDKAIAHIKAGAKKVLLTGPSKGGHVQMVVKGVNDNQLDIEAFDIFSNASCTTNCIGP
                     VAKVLNNQFGIVNGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALK
                     EVLPELEGKLHGMALRVPTKNVSLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQ
                     PLVSVDFNTNPNSAIIDAKSTMVMSGNKVKVIAWYDNEWGYSNRVVDVAEQIGALLTS
                     KETVSAS"
     gene            14937..15407
                     /gene="nrdR"
                     /locus_tag="RFE25_000011"
     CDS             14937..15407
                     /gene="nrdR"
                     /locus_tag="RFE25_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDU2815125.1"
                     /translation="MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHI
                     EVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTE
                     VSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA"
     gene            15408..16808
                     /locus_tag="RFE25_000012"
     CDS             15408..16808
                     /locus_tag="RFE25_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HDU2815126.1"
                     /translation="MGRQAFEFGLRPKDQFKVMQHFDLNTNHLEVLNRLYTPLIGTQA
                     VGLYHFMTQFVKDSHNETLILSHYIFMNELKINLLEFRQQMDLLEAIGLLKAFVKHDE
                     QETQFVYQLIQPPSAHLFFNDPMLSIFLYSEVEHRRFHELKKYFEYQQIDLSEFKQVT
                     RQFTDVFKVPSTKIDIDTSDIPINEPYQGIDLSNESFDFEMLRQMLGKHFISQDIVTK
                     DAKRLITQLATLYGLTADGMKHVILNSITSGQQLSFEEMRKQARSYYLMEHENQMPKL
                     QVKSPATSSSTGKSSEVNPKPQSDEWFELLEQTSPIDMLASWSESEPTISQKTMVEEL
                     IEREKMSFGVINILLQFVMLKEDMKLPKAYILEIASNWKKKGIKTAKEAYNYAKKVNQ
                     PKNEGSSGNYQKRGSYYGQRNRISKEKTPKWLENRDKPSEEDSAKDNSVDDQQLEQDR
                     QAFLDKLSKKWEEDSR"
     gene            16808..17728
                     /gene="dnaI"
                     /locus_tag="RFE25_000013"
     CDS             16808..17728
                     /gene="dnaI"
                     /locus_tag="RFE25_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HDU2815127.1"
                     /translation="MKQFKSIINTSQDFEKRIEKIKKEVINDPDVKQFLEAHRAELTN
                     AMIDEDLNVLQEYKDQQKHYDGHKFADCPNFVKGHVPELYVDNNRIKIRYLQCPCKIK
                     YDEERFEAELITSHHMQRDTLNAKLKDIYMNHRDRLDVAMAADDICTAITNGEQVKGL
                     YLYGPFGTGKSFILGAIANQLKSKKVRSTIIYLPEFIRTLKGGFKDGSFEKKLHRVRE
                     ANILMLDDIGAEEVTPWVRDEVIGPLLHYRMVHELPTFFSSNFDYSELEHHLAMTRDG
                     EEKTKAARIIERVKSLSTPYFLSGENFRNN"
     gene            17821..17943
                     /locus_tag="RFE25_000014"
     CDS             17821..17943
                     /locus_tag="RFE25_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815128.1"
                     /translation="MFDENMVNKLDDYYFIYGICNEYPDQDRYLKQRYLIHKLY"
     gene            18141..20078
                     /gene="thrS"
                     /locus_tag="RFE25_000015"
     CDS             18141..20078
                     /gene="thrS"
                     /locus_tag="RFE25_000015"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDU2815129.1"
                     /translation="MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNG
                     QLVDLTKPLETDGSIEIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEG
                     GFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKLELI
                     DAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIY
                     GTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRRE
                     IERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPM
                     NCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRP
                     DQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEA
                     ADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDG
                     EHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQ
                     DELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQE
                     TVEKDEFIWNLVDEIRLKKHR"
     gene            20504..21997
                     /locus_tag="RFE25_000016"
     CDS             20504..21997
                     /locus_tag="RFE25_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDU2815130.1"
                     /translation="MSKVQNESNNVVKRGLKDRHISMIAIGGCIGTGLFVTSGGAIHD
                     AGALGALIGYAIIGIMVFFLMTSLGEMATYLPVSGSFSTYATRFVDPSLGFALGWNYW
                     FNWVVTVAADITIAAQVIQYWTPLQGIPAWAWSALFLVIIFSLNSLSVRVYGESEYWL
                     ALIKVITVIVFIAIGLLTIVGIMGGHVVGFEIFNKGEGPILGGNLGGSLLSILGVFLI
                     AGFSFQGTELIGITAGESENPERAVPKAIKQVFWRILLFYILAIFVIGMLIPYDSSAL
                     MGGSDNVATSPFTLVFKNAGFAFAASFMNAVILTSVLSAGNSGMYASTRMLYSMSKDK
                     LAFEAFGKTNKNGVPYMSLLVTAIIVVIIFVLQSLTKGAYEYIVAASGLTGFIAWVGI
                     AVSHYRFRRAFDKQNYDKSKLKYTAKLFPFGPLFAGFLCIVVIIGQDVDFIKTGDFNF
                     SRFLITYMGIPVFLAFFIYHKLRYKTKKIPLEQVDLRQDVSMDEIKG"
     misc_feature    22072..22197
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            22226..22753
                     /gene="infC"
                     /locus_tag="RFE25_000017"
     CDS             22226..22753
                     /gene="infC"
                     /locus_tag="RFE25_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDU2815131.1"
                     /translation="MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAER
                     VDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHD
                     FQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKM
                     DGRQMFIMLAPTAEK"
     gene            22782..22982
                     /gene="rpmI"
                     /locus_tag="RFE25_000018"
     CDS             22782..22982
                     /gene="rpmI"
                     /locus_tag="RFE25_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDU2815132.1"
                     /translation="MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQL
                     RKARLVSKSDMKRVKQLLAYKK"
     gene            23029..23385
                     /gene="rplT"
                     /locus_tag="RFE25_000019"
     CDS             23029..23385
                     /gene="rplT"
                     /locus_tag="RFE25_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDU2815133.1"
                     /translation="MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQ
                     YAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISD
                     EKAFAQLVTKAKDALK"
     gene            23527..24135
                     /locus_tag="RFE25_000020"
     CDS             23527..24135
                     /locus_tag="RFE25_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDU2815134.1"
                     /translation="MSKFDEQIIVVPREIIFNNEKNTFNGFLNKNKPEGQNIFDALSQ
                     YEVKRRGDMEEDPSYKQLISYCLLENEHGEILVYERLSGGGEARLHGQSSIGVGGHMN
                     DVPGAESINEVLRVNAQRELEEEVGLSEQDSQNMEYIGFINDDNNEVGKVHIGVVFKI
                     TVSTNDVEAKETDTLRIKWVEKGNIESYDDFETWSALILQDL"
     gene            24154..25083
                     /locus_tag="RFE25_000021"
     CDS             24154..25083
                     /locus_tag="RFE25_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815135.1"
                     /translation="MSDIIQFPNSSKKLYKDIKRAEQDQNYDLMYEYIVQYERQFELT
                     EEIAMMKCRMLYETGSFLELREETIVLLKTGIQQYDALMIYYVKSLIGLGQYFEAVEV
                     IHQIIDEVKDHKTRMALHPLKEFAKSKLIEDEKRLTQSLTDFDTLSMREQTHLILKLI
                     DNGHFQFQETVLYILKSNTYSYNLISLMIEYLRFANCTQELTIEKYGMDVTFVPANLN
                     GLEHTTLKEKVIPNVMETLNDGALHIAEEAHHIMNNHSIMIYPIDIETLFETNKWINA
                     YECYFKNMLGLKCELQSIDAFNFIQQLDLNNNS"
     gene            25088..25198
                     /locus_tag="RFE25_000022"
     CDS             25088..25198
                     /locus_tag="RFE25_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815136.1"
                     /translation="MQNNTQHFNIVLTKKVDLQIYKRCDFNVCIGNRPMI"
     gene            25246..26547
                     /locus_tag="RFE25_000023"
     CDS             25246..26547
                     /locus_tag="RFE25_000023"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDU2815137.1"
                     /translation="MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGF
                     RKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGK
                     DFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVV
                     ENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVT
                     FPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRL
                     AEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTY
                     FQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNI
                     SVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED"
     gene            26698..27960
                     /gene="clpX"
                     /locus_tag="RFE25_000024"
     CDS             26698..27960
                     /gene="clpX"
                     /locus_tag="RFE25_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDU2815138.1"
                     /translation="MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSE
                     IVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPK
                     EDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
                     LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTA
                     SVPPQGGRKHPNQEMIQIDTTNILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYD
                     EQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNILTQPKNALVKQYTKM
                     LELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVI
                     TAQTINEETEPELYDAEGNLINNSKTSA"
     gene            28114..28704
                     /locus_tag="RFE25_000025"
     CDS             28114..28704
                     /locus_tag="RFE25_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDU2815139.1"
                     /translation="MKVNPNNIELIISAVKEEQYPETELSEVALSGRSNVGKSTFINS
                     MIGRKNMARTSQQPGKTQTLNFYNIDEQLIFVDVPGYGYAKVSKTQREKFGKMIEEYI
                     TKRENLQLVIQLVDLRHDPTQDDILMYNYLKHFDIPTLVICTKEDKIPKGKVQKHIKN
                     IKTQLDMDPDDTIVSYSSIQNNKQQQIWNLIEPYIS"
     gene            28921..30267
                     /locus_tag="RFE25_000026"
     CDS             28921..30267
                     /locus_tag="RFE25_000026"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HDU2815140.1"
                     /translation="MHFIAISINHRTADVALREQVAFRDDALRIAHEDLYETKSILEN
                     VILSTCNRTEVYAVVDQIHTGRYYIQRFLARAFGFEVDDIKAMSEVKVGDEAVEHLLR
                     VTSGLDSIVLGETQILGQIRDAFFLAQSTGTTGTIFNHLFKQAITFAKRAHNETDIAD
                     NAVSVSYAAVELAKKVFGKLKSKQAIIIGAGEMSELSLLNLLGSGITDITVVNRTIEN
                     AMKLAAKHQVKYDELSSLPNLLESADIVISSTSAQSYIITNEMIERIAENRKQDSLVL
                     IDIAVPRDIEPGISAITNIFNYDVDDLKGLVDANLRERQLAAATISEQIPAEIHAHNE
                     WISMLGVVPVIRALREKAMAIQAETMDSIDRKLPGLSERERKIISKHTKSIINQMLKD
                     PIKQAKELSSDKKSNEKLELFQNIFDIEAECPHEQAKQQKESKVKEISARRIFSFE"
     gene            30289..31104
                     /gene="ccsA"
                     /locus_tag="RFE25_000027"
     CDS             30289..31104
                     /gene="ccsA"
                     /locus_tag="RFE25_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcsA"
                     /protein_id="HDU2815141.1"
                     /translation="MQENLFIRFNEIILLIYLISIICYFYDFVQKSHKIRSLGIYLLG
                     IVWVLQTISLSIFIIQTRHIPLGSISDVFYTLSWLIISISLILNLIKVLNFSVFFLNL
                     IGLTLLGMNTFQPTHYTNKVQKIAVVDELLLVHIGLAVLSYVFFALAFVNALLYIMQY
                     RNLKEKRFDQKYFRIGSVATLESIVFYSTLSGWIILIFSIILGTQWGVISVGERIFID
                     PKVILSSIITVLYGSYILLRINKWLNSRYLIYYNIILFCLNMINLFFATHFVN"
     gene            31146..32072
                     /gene="hemC"
                     /locus_tag="RFE25_000028"
     CDS             31146..32072
                     /gene="hemC"
                     /locus_tag="RFE25_000028"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDU2815142.1"
                     /translation="MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGD
                     RIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELP
                     FDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTE
                     DYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKV
                     HNDEVAKCVTAERTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTM
                     NGTDPVELGKTVSNKLKEQGAYEIIKRLNEQH"
     gene            32094..32762
                     /locus_tag="RFE25_000029"
     CDS             32094..32762
                     /locus_tag="RFE25_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HDU2815143.1"
                     /translation="MKPVVVMTQTNDMQSDLVSIIHKPFIDIKPLNFDIHLLNQRYDW
                     LIFSSKNAVKFFYKYLKGINVDNIAVIGSKTAQYCESLGIRVDFMPNDFSQEGFLKSF
                     NQTNQKILLPSSELARPLLLAALSKDNEVVKIDLYTSVPNKQNIQDVKEMIEHQQIDA
                     LTFSSSSAVRYYFNEGFVPKFKSYFAIGEQTARTIKTYQQPVTIAEIQTLESLIEKIL
                     ESRG"
     gene            32765..33739
                     /gene="hemB"
                     /locus_tag="RFE25_000030"
     CDS             32765..33739
                     /gene="hemB"
                     /locus_tag="RFE25_000030"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001633925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDU2815144.1"
                     /translation="MKFDRHRRLRSSATMRDMVRENHVRKEDLIYPIFVVEKDDVKKE
                     IKSLPGVYQISLNLLESELKEAYDLGIRAIMFFGVPNSKDDIGTGAYIHDGVIQQATR
                     IAKKMYDDLLIVADTCLCEYTDHGHCGVIDDHTHDVDNDKSLPLLVKTAISQVEAGAD
                     IIAPSNMMDGFVAEIRRGLDEAGYYNIPIMSYGVKYASSFFGPFRDAADSAPSFGDRK
                     TYQMDPANRLEALRELESDLKEGCDMMIVKPALSYLDIVRDVKNHTNVPVVAYNVSGE
                     YSMTKAAAQNGWIDEERVVMEQMVSMKRAGADMIITYFAKDICRYLDK"
     gene            33787..35073
                     /gene="hemL"
                     /locus_tag="RFE25_000031"
     CDS             33787..35073
                     /gene="hemL"
                     /locus_tag="RFE25_000031"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDU2815145.1"
                     /translation="MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGS
                     KIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVI
                     DRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVA
                     TLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGDDIAGVIVEPVAGNMGVVPPI
                     EGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVG
                     AFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILED
                     GLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVF
                     LPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK"
     gene            35134..35235
                     /locus_tag="RFE25_000032"
     CDS             35134..35235
                     /locus_tag="RFE25_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815146.1"
                     /translation="MGGDLIVKVHICFVVKTASGYCYLNKREAQAAI"
     gene            35269..36342
                     /locus_tag="RFE25_000033"
     CDS             35269..36342
                     /locus_tag="RFE25_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDU2815147.1"
                     /translation="MTMIYRNNFIVFVLSFFISIILYSSHVLLPFMFGPIIASIICVK
                     VFKLDIKWPFLLSELGIVLLGVQIGSTFTKNVVMDIKNNWLSIIVVSISILLIAIVMA
                     FIFKKIARINTETAILSVIPGALTQMLVMAEQDKRANLLVVSLTQTSRIIFVVVLVPF
                     ISYFFHDGNMHANGKLTKVLPLSQVLNIGQIVILAIAIFIVYLIMSKIKFPTFQLLAP
                     LIVLIVWNFSTGLTFTLDHWLLNMAQLIYMIRIGVQIAHLLSDLKGRLAIAITIQNIM
                     LIIGALIMVYIIHFFDNNPINELFLGAAPGGVNQIVLVALATGADVAMITSYHIFRIF
                     FILFIIAPGINYFLKYRSNKRED"
     gene            complement(36565..37125)
                     /locus_tag="RFE25_000034"
     CDS             complement(36565..37125)
                     /locus_tag="RFE25_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDU2815148.1"
                     /translation="MNECAFGTKDPVYLNYHDHVWGQPLYDSKALFKLLALESQHAGL
                     SWLTILKKKEAYEEAFYDFEPEKVAQMTAQDIDRLMTFPNIVHHRKKLEAIVNQAQGY
                     LKIEQAYGSFSKFLWSYVNGKPKDLQYEHASDRITVDDTATQLSKDLKQYGFKFLGPV
                     TVFSFLEAAGLYDAHLKDCPSKPKHN"
     misc_binding    37183..37484
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            37528..40158
                     /locus_tag="RFE25_000035"
     CDS             37528..40158
                     /locus_tag="RFE25_000035"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDU2815149.1"
                     /translation="MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPP
                     NVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGIT
                     RYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVD
                     LYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTR
                     PETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPA
                     HDPNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVKDLKEQDLVIKI
                     EDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFN
                     QWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSS
                     ALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVL
                     LHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVES
                     VWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDK
                     YEFGEVGRALYNFIWDDFCDWYIEMSKIPMNSNDEEQKQVTRSVLSYTLDNIMRMLHP
                     FMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEV
                     NTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIA
                     GKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRK
                     KQDYQEKYDGVKARIEQLKA"
     gene            40171..41442
                     /locus_tag="RFE25_000036"
     CDS             40171..41442
                     /locus_tag="RFE25_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDU2815150.1"
                     /translation="MNYLESLYWIHERTKFGIKPGVKRMEWMLAQFNNPQNNIKGIHV
                     GGTNGKGSTVAYLRTALVENGYEVGTFTSPFIETFNERISLNGVPISNDAIVELVSRI
                     KPVSEMMERETDLGVATEFEIITAMMFLYFGEIHPVDFVIVEAGLGIKNDSTNVFTPV
                     LSILTSIGLDHTDILGGTYLDIARDKGAIIKPNVPVIYAVKNEDALKYVRERAIEQHA
                     KPIELDREIVVVSQNDEFTYRYKDYELETIILSMLGEHQKQNAALAITALIELNEQGL
                     IELDFNKMIDGIESVRWTGRIEQVHDKPLIILDGAHNSESIDALIDTIKQYHDKEKVD
                     ILFSAINGKPINEMVKHLSLIAHTFYATEFDFPKALRKEEIVGSIENDEIQLVDDYVE
                     FIKNYQGDTLVITGSLYFISEVKSKLDFEAL"
     gene            41712..42419
                     /locus_tag="RFE25_000037"
     CDS             41712..42419
                     /locus_tag="RFE25_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDU2815151.1"
                     /translation="MVVLLSYSCSCIFSFLYQFISIEETSFDYLHRRSKCDYCNSSLK
                     WYELMPIISFLLLKGRCRNCRKRISLTHFLGETFALIPIVFIKYDFTYVNATLFITTY
                     VFLLIFTMTDITSLMLDCRLIIIYCIVSLSLSMIYPVAFIIISMTTHIFYFLFRAYIG
                     YGDVLLISALSLFFPLQFTIYVILFTFVIAGLVALITMIFKPIKLLPLVPFIFISFFI
                     NSLFYNDIHQFLGGVYF"
     gene            42416..42955
                     /gene="radC"
                     /locus_tag="RFE25_000038"
                     /pseudo
     CDS             42416..42955
                     /gene="radC"
                     /locus_tag="RFE25_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
     gene            43089..44174
                     /locus_tag="RFE25_000039"
     CDS             43089..44174
                     /locus_tag="RFE25_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDU2815152.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            44171..46063
                     /locus_tag="RFE25_000040"
     CDS             44171..46063
                     /locus_tag="RFE25_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDU2815153.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            46070..46447
                     /locus_tag="RFE25_000041"
     CDS             46070..46447
                     /locus_tag="RFE25_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDU2815154.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            46598..47380
                     /locus_tag="RFE25_000042"
     CDS             46598..47380
                     /locus_tag="RFE25_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HDU2815155.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(47506..48237)
                     /gene="erm(A)"
                     /locus_tag="RFE25_000043"
     CDS             complement(47506..48237)
                     /gene="erm(A)"
                     /locus_tag="RFE25_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HDU2815156.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            48625..49287
                     /locus_tag="RFE25_000044"
     CDS             48625..49287
                     /locus_tag="RFE25_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDU2815157.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
     gene            49498..49668
                     /locus_tag="RFE25_000045"
                     /pseudo
     CDS             49498..49668
                     /locus_tag="RFE25_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002453405.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            49736..50020
                     /locus_tag="RFE25_000046"
     CDS             49736..50020
                     /locus_tag="RFE25_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815158.1"
                     /translation="MTLFIIIGVLVPMVYTMQLNIKNEPVTKRNLLITLALSTLGILV
                     TALAGVIVTKQAFPLLSVAIGSIFTGIVWGLLLSGSYALIRFLSNAFGRK"
     gene            complement(50137..50334)
                     /locus_tag="RFE25_000047"
     CDS             complement(50137..50334)
                     /locus_tag="RFE25_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815159.1"
                     /translation="MSILTIILIALLVILLFRVGLSILRFLIYVGLVLLCIYLGYQGL
                     IWLLDFFQINSGFLPHFQFNN"
     gene            50494..50967
                     /locus_tag="RFE25_000048"
     CDS             50494..50967
                     /locus_tag="RFE25_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4930 family protein"
                     /protein_id="HDU2815160.1"
                     /translation="MRLIFSMIKNIIAVIAIVIIVYIALKYAPFLKEQDWNPVNHDND
                     QMNQVTQPTNDAQHVYVSGEKYSLKENDLIKNVPLSQIKNVFKMIDKQEFMAVSGMNR
                     MAYNDQYIIGQRGDEFILYKFGDESMRVYNTEFEMQQDLNELGQNLQLKPENAYQ"
     gene            51041..51160
                     /locus_tag="RFE25_000049"
     CDS             51041..51160
                     /locus_tag="RFE25_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815161.1"
                     /translation="MAEQSKQKQANEQQKAQNLFARWRQLQNSNSESSNDTNK"
     gene            51359..52201
                     /gene="mreC"
                     /locus_tag="RFE25_000050"
     CDS             51359..52201
                     /gene="mreC"
                     /locus_tag="RFE25_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDU2815162.1"
                     /translation="MLKFFKNNKLIVVLCAIIVFIALIGLSIRSQSQSPPEQYIGDSV
                     SFGQRVVSYPVNFVAGTIGDFFKKGDSKESKNKISQLESKNQQLEAENEKLKKELDLK
                     DISKFDPISTTVLARNPDQWMNTIVIDKGSKSGITSNMAVMTSQGFVGRVTKVNKFSS
                     QVDLISTNTRAGKLSVNIQHGSKNIFGLIDRYDEKNSELVISDINNRDNISKGDKVVT
                     SGLADQLPSNLYIGEVTKVQNDQYGLAKEVRVKTGADLTDLSHVYVAKRDPKTIPDDE
                     SRDK"
     gene            52201..52731
                     /gene="mreD"
                     /locus_tag="RFE25_000051"
     CDS             52201..52731
                     /gene="mreD"
                     /locus_tag="RFE25_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDU2815163.1"
                     /translation="MRTLYYFLIGILLFYIDTAIGLLIPMHIGKFELVFVPHLTFMYI
                     LMMVVYRGFGVSLLLSIFLGVMTDVYFGSIYGVYLFGYILFLALIDRFFKIFYKDHSM
                     LFIIILASTLLLEVYVVLIYGMLGFIQFDIIHFVVFRLLPTLIMNFVLLIMLYPLIIK
                     FLKKTNNDIDMKRRQW"
     misc_feature    52758..52954
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            52967..53275
                     /gene="rplU"
                     /locus_tag="RFE25_000052"
     CDS             52967..53275
                     /gene="rplU"
                     /locus_tag="RFE25_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDU2815164.1"
                     /translation="MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGD
                     SVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA
                     "
     gene            53281..53601
                     /locus_tag="RFE25_000053"
     CDS             53281..53601
                     /locus_tag="RFE25_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDU2815165.1"
                     /translation="MITVDITVNDEGKVTDVIMDGHADHGEYGHDIVCAGASAVLFGS
                     VNAIIGLTSERPDINYDDNGGHFHIRSVDTNNDEAQLILQTMLVSLQTIEEEYNENIR
                     LNYK"
     gene            53613..53897
                     /gene="rpmA"
                     /locus_tag="RFE25_000054"
     CDS             53613..53897
                     /gene="rpmA"
                     /locus_tag="RFE25_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009382703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDU2815166.1"
                     /translation="MLKLNLQFFASKKGVSSTKNGRDSESKRLGAKRADGQFVTGGSI
                     LYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVAE"
     gene            54251..55543
                     /gene="obgE"
                     /locus_tag="RFE25_000055"
     CDS             54251..55543
                     /gene="obgE"
                     /locus_tag="RFE25_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020444729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDU2815167.1"
                     /translation="MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASV
                     VFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDE
                     VLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
                     VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIE
                     GASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRP
                     QIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDV
                     DFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAV
                     RRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE"
     gene            55556..56011
                     /locus_tag="RFE25_000056"
     CDS             55556..56011
                     /locus_tag="RFE25_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDU2815168.1"
                     /translation="MDNKDYKKFYLIREDVLPESVVKTLKIKDALKSDPTLSIYDAVK
                     QFDLSRSAFYKYRETIFPVDDKMLDHREFTLILYVTDIVGMLARVLDVISKLELSVLT
                     IHQSIPMEEKATITLSLNAKSKETSVEDVIGALRNLDYVSKVELISMSM"
     gene            56025..56627
                     /gene="ruvA"
                     /locus_tag="RFE25_000057"
     CDS             56025..56627
                     /gene="ruvA"
                     /locus_tag="RFE25_000057"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDU2815169.1"
                     /translation="MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEV
                     LIRTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIE
                     NENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAML
                     ALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS"
     gene            56659..57663
                     /gene="ruvB"
                     /locus_tag="RFE25_000058"
     CDS             56659..57663
                     /gene="ruvB"
                     /locus_tag="RFE25_000058"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDU2815170.1"
                     /translation="MNERMVDQSMHSEETDFELSLRPTRLRQYIGQNSIKSNLEVFIK
                     AAKLRHEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTVSGPSLERPGDLAAILSGL
                     QPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATT
                     RAGSLTGPLRDRFGVHLRLEYYNESDLKEIIIRTAEVLGTGIDEESAIELAKRSRGTP
                     RVANRLLKRVRDFQQVNEDEQIYIETTKHALGLLQVDQHGLDYIDHKMMNCIIKQYNG
                     GPVGLDTIAVTIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYEHFAKSNEERG
                     "
     gene            57665..58690
                     /gene="queA"
                     /locus_tag="RFE25_000059"
     CDS             57665..58690
                     /gene="queA"
                     /locus_tag="RFE25_000059"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDU2815171.1"
                     /translation="MNIEEFDYDLPESLIAQTPLKDRDHSRLLVMDRETGEMKHLHFK
                     DIIEYFRPGDTLVLNDTRVMPARLFGLKEETGAKVEMLMLTQIEGNDWEVLLKPAKRI
                     KVGNKLNFGNGKIIAECIKEMDQGGRIMRLHYEGILQERLDELGEMPLPPYIKERLDD
                     PDRYQTVYAKESGSAAAPTAGLHFTDELLTEIKNKGVNIAFVTLHVGLGTFRPVSVDD
                     VNDHEMHSEYYQMTQETADLLNDTKSKGHRIISVGTTSTRTLETIRRDHDKFVETSGW
                     TNIFIYPGFDFKAIDGQITNFHLPKSTLVMLVSAFSTRENVLNAYKTAVNLEYRFFSF
                     GDAMLII"
     gene            58713..59852
                     /gene="tgt"
                     /locus_tag="RFE25_000060"
     CDS             58713..59852
                     /gene="tgt"
                     /locus_tag="RFE25_000060"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016425271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDU2815172.1"
                     /translation="MPAVTYEHIKTCKQSGARLGIVHTPHGSFETPMFMPVGTKATVK
                     TMSPEELRQIEAKIILGNTYHLWLQPGNDIIKHAGGLHKFMNWDGPILTDSGGFQVFS
                     LSNLRKITEEGVEFRHHTNGSKLFLSPEKSMQIQNDLGSDIMMAFDECPPMPAEYDYV
                     KKSIERTTRWAKRCLDAHQRPEDQALFGIIQGGEYEDLREQSAKDLVELDFPGYAIGG
                     LSVGEPKPVMYKMVEHTEQFMPKDKPRYLMGVGSPDALIECSIRGMDMFDCVLPTRIA
                     RNGTCMTSQGRLVIKNAKFADDLRPLDENCDCYTCQNYSRAYIRHLIKAEETFGIRLT
                     TIHNLHFLLKLMEDIRQAIREDRLLDFKEEFFEQYGLNVENPKNF"
     gene            59871..60131
                     /gene="yajC"
                     /locus_tag="RFE25_000061"
     CDS             59871..60131
                     /gene="yajC"
                     /locus_tag="RFE25_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDU2815173.1"
                     /translation="MQFSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRI
                     TTIGGIKGTVKAVDETTVVITVNGHGTELTFEKPAIKQVDPS"
     gene            60406..62685
                     /gene="secDF"
                     /locus_tag="RFE25_000062"
     CDS             60406..62685
                     /gene="secDF"
                     /locus_tag="RFE25_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecDF"
                     /protein_id="HDU2815174.1"
                     /translation="MKKSSRIIAFLLLVVLLFAGMAATYKSVIKNVNLGLDLQGGFEV
                     LYQVDPLNKGDKIDKKALQSTAQTLENRVNVLGVSEPKIQVEEPNRIRVQLAGVTDQN
                     EARKILSSQANLTIRDAEDKVKLSGSDIKQGSAKQEFKQETNQPTVTFKVKDKNKFKK
                     VTEEISKKRDNVMVVWLDFKKGDSYKKEAQKKNPKFISAASVDQPINSDSVEISGGFK
                     GQEGVKKAKQIAELLNAGSLPVDLKEIYSNSVGAQFGQDALDKTVFASFIGVALIYLF
                     MLGFYRLPGLVAIIALTTYIYLTLVAFNFISGVLTLPGLAALVLGVGMAVDANIIMYE
                     RIKDELRIGRTIKQAFSKANKSSFLTIFDSNLTTVIAAAVLFFFGESSVKGFATMLLL
                     GILMIFVTAVFLSRFLLSLLVSSNIFKNQFWLFGVKKNKRHDINEGVDVHDLKTSFEK
                     WNFVKLAKPLIGVSILIVVVGLVILYIFKLNLGIDFSSGTRVDFQSKQAITQQKVEQV
                     VKDSGLKADQIQINGKDNKVATVQFKDDLTRAQDNKLSDNIKSKFGDTPQINTVSPII
                     GQELAKNAMLALIYASIGIIIYVSLRFEWRMGLSSVLALLHDVFIIVAIFSLFRIEVD
                     LTFIAAVLTIVGYSINDTIVTFDRVRENLQKVKVITTTEQIDDIVNRSIRQTMTRSIN
                     TVLTVIVVVVAILFFGAPTIFNFTLALFIGLISGVFSSIFIAVPLWGIMKKRQLKKSP
                     KHKLVVYKEKKSNDEKILV"
     gene            62888..65161
                     /gene="recJ"
                     /locus_tag="RFE25_000063"
     CDS             62888..65161
                     /gene="recJ"
                     /locus_tag="RFE25_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDU2815175.1"
                     /translation="MIKPKYKWKLTKPAEYISDELTSKLKLTPIVKKILESKSIIDEQ
                     AIESIISDTDVNHDALQLSDMTKAIERIKRAIANDEKILVYGDYDADGVTSTTILVTT
                     LQLLGAQVGWHIPNRFTEGYGPNELAFRNAHDEGITLIITVDNGIQGHNEIKMVQDLG
                     VDVIVTDHHEIGSTLPEAYAIVHPMHPSFNYPFQQLCGAGVAYKLAQALIENVPDYFK
                     ALVAIGTIADLVSLTDENRSLVKQGLKVLNDQCPTSVKALLKEAGYNDNIDEETIGFI
                     IGPRLNAVGRLDDASLACELLMTDDEEEAAFLAEQVEHFNRERKDIVATITEEAMAMA
                     ETKVKKGDLFLLLAKENWHEGVLGIVASKIVETFALPTLILNIDREQNHAKGSARSID
                     QVSMFEILSAHQELIAKFGGHHMAAGMTMDIENIESLAEGLNKWMKELSKTTSLDPVK
                     PVDVLLTENDITIKNIRDMNRLRPFGTDFSRPIFEMDDLSVSSVKAIGQQKNHLKLTL
                     GESNIAALFWQNGHLEPELQDEQPINILGSVQINEWNGNQSPQLIIQDIAMNEQQILD
                     YRSKRKSLPFTENDENIVVLIHPKSDKVNANEYYYGEEIKQQTDKVVLRDLPTSMEDL
                     SNSLQQLQFSQLYIVLQHNHSIYFDGIPNMDIFKKCYKALITKQETNIQKEGMLLCQH
                     LSVKPDTLKFMLKVFLDLKFVTQEDGLIRINQQPDKRSIDSSKVYQLRQQRMDVEKQL
                     LYQDFSEIKNWIKSQLS"
     gene            65183..65701
                     /locus_tag="RFE25_000064"
     CDS             65183..65701
                     /locus_tag="RFE25_000064"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009559512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDU2815176.1"
                     /translation="MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYA
                     KDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLT
                     MHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIK
                     DYDVMSLISYDE"
     gene            66129..68318
                     /locus_tag="RFE25_000065"
     CDS             66129..68318
                     /locus_tag="RFE25_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDU2815177.1"
                     /translation="MNNEYPYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFR
                     KNGLPYIMHPIQVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIV
                     DGVTKLKKVKYRSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQ
                     IRISRETLEIYAPLAHRLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAYI
                     ETAIDRIRTEMDRMNIEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLAIRVIVNSIN
                     DCYAILGLVHTLWKPMPGRFKDYIAMPKQNLYQSLHTTVVGPNGDPLEIQIRTFDMHE
                     IAEHGVAAHWAYKEGKKVSEKDQTYQNKLNWLKELAEADHTSSDAQEFMETLKYDLQS
                     DKVYAFTPASDVIELPYGAVPIDFAYAIHSEVGNKMIGAKVNGKIVPIDYILQTGDIV
                     EIRTSKHSYGPSRDWLKIVKSSSAKGKIKSFFKKQDRSSNIEKGRMMVEVEIKEQGFR
                     VEDILTEKNIQVVNEKYNFANEDDLFAAVGFGGVTSLQIVNKLTERQRILDKQRALNE
                     AQEVTKSLPIKDNIITDSGVYVEGLENVLIKLSKCCNPIPGDDIVGYITKGHGIKVHR
                     TDCPNIKNETERLINVEWVKSKDATQKYQVDLEVTAYDRNGLLNEVLQAVSSTAGNLI
                     KVSGRSDIDKNAIINISVMVKNVNDVYRVVEKIKQLGDVYTVTRVWN"
     gene            68330..68783
                     /locus_tag="RFE25_000066"
                     /pseudo
     CDS             68330..68783
                     /locus_tag="RFE25_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
     gene            68780..69655
                     /locus_tag="RFE25_000067"
     CDS             68780..69655
                     /locus_tag="RFE25_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDU2815178.1"
                     /translation="MKKIEAWLSKKGLKNKRTLIVVIAFVLFIIFLFLLLNSNSEDSG
                     NITITENAELRTGPNAAYPVIYKVEKGDHFKKIGKVGKWIEVEDTSSNEKGWIAGWHT
                     NLDIVADNTKEKNPLQGKTIVLDPGHGGSDQGASSNTKYKSLEKDYTLKTAKELQRTL
                     EKEGATVKMTRTDDTYVSLENRDIKGDAYLSIHNDALESSNANGMTVYWYHDNQRALA
                     DTLDATIQKKGLLSNRGSRQENYQVLRQTKVPAVLLELGYISNPTDETMIKDQLHRQI
                     LEQAIVDGLKIYFSA"
     gene            70116..71378
                     /locus_tag="RFE25_000068"
     CDS             70116..71378
                     /locus_tag="RFE25_000068"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDU2815179.1"
                     /translation="MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFE
                     STDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPI
                     KLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLK
                     LVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIK
                     TAPRITDFLNEESKAYYEQVKAYLDDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNY
                     DGAITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFI
                     VTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELE
                     NNKIDVKNMTTGESETIELDALVEYFKK"
     gene            71394..73160
                     /gene="aspS"
                     /locus_tag="RFE25_000069"
     CDS             71394..73160
                     /gene="aspS"
                     /locus_tag="RFE25_000069"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDU2815180.1"
                     /translation="MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDRE
                     GIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNI
                     KVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDD
                     EGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQI
                     VKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPR
                     MTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAE
                     QYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGD
                     LVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAA
                     HHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGF
                     TKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCL
                     LTNAPGEVSDKQLEELSLRIRH"
     gene            73238..73428
                     /gene="ssrS"
                     /locus_tag="RFE25_000070"
     ncRNA           73238..73428
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RFE25_000070"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            73493..73621
                     /locus_tag="RFE25_000071"
     CDS             73493..73621
                     /locus_tag="RFE25_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815181.1"
                     /translation="MGFIAFNKCFLVEFWENNQSDNAKYKILSYYVLMYKSVKEVK"
     gene            73621..74394
                     /locus_tag="RFE25_000072"
     CDS             73621..74394
                     /locus_tag="RFE25_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDU2815182.1"
                     /translation="MKHQFSRNELAIGQQGLDLLKQQTVVILGVGGVGSFAAEALART
                     NIGHIILIDKDDVDITNVNRQLHALTTTVGQSKVSLMEERIKLINPDCKVTPLHMFYT
                     EETYEEIFDNYDIDYFVDASDTIMYKVHLMKECLDRGIKVISSMGAANKTDPTRFTIS
                     DISKTHTDPMAKIIRQKLKKLGIRKGIPVVFSDESPIVIREDVKDIVGDKNAINRKGQ
                     MPPSSNAFVPSVVGLICASYVVNDVLKDIPVRRIKDKGQ"
     gene            complement(74555..75829)
                     /locus_tag="RFE25_000073"
     CDS             complement(74555..75829)
                     /locus_tag="RFE25_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500242.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDU2815183.1"
                     /translation="MSTEPLASRMRPKNIDEIISQQHLVGPKGIIRRMVDTKKLTSMI
                     FYGPPGIGKTSIAKAISGSTQYKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIH
                     RLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLNDEDVRQAL
                     TRAIEDDENGLKTYQPKIDEDAMTYFSTQSQGDVRSALNALELAVLSADNDKDGYRHV
                     TLQDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTI
                     VRRLLVISYEDIGLALPNAGQRTLAAIESAERLGLPEARIPLSQAVIELCLSPKSNSA
                     MSAIDSALSDIRNGHVGQIPNHLKDGHYQGAKDLGRSIGYKYPHQYVNGYVSQQYLPD
                     KLKNKIYYEPKTTSKSEQQLKEIYNNLLKQRP"
     gene            75914..76336
                     /locus_tag="RFE25_000074"
     CDS             75914..76336
                     /locus_tag="RFE25_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDU2815184.1"
                     /translation="MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQ
                     LVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQ
                     LWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI"
     gene            76436..76618
                     /locus_tag="RFE25_000075"
     CDS             76436..76618
                     /locus_tag="RFE25_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDU2815185.1"
                     /translation="MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVV
                     ENAKNKITDAIDKLKK"
     gene            76658..76804
                     /locus_tag="RFE25_000076"
     CDS             76658..76804
                     /locus_tag="RFE25_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815186.1"
                     /translation="MSFMDKAKDAVEKFKNSDNEQVKNVKDKINEYTGSNNEEKKENE
                     DKEK"
     gene            complement(77041..78054)
                     /locus_tag="RFE25_000077"
     CDS             complement(77041..78054)
                     /locus_tag="RFE25_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDU2815187.1"
                     /translation="MAIKYSALNLVPIREGDDERTAINDMVKLAQHLDELSYERYWIA
                     EHHNAPNLVSSATALLIQHTLEHTKHIRVGSGGIMLPNHAPLIVAEQFGTMATLFPNR
                     VDLGLGRAPGTDMMTASALRRDQHDGVYKFPEEVSLLQQYFGPAHQQAYVRAYPAVGK
                     NVPLYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEAIEIYKTLFEPSDVLDEPYVI
                     VCLNTIVAENDDEAQYLASSMAQVMVSITRGRMQPVQPPTHDLQNILTPREYAMAMER
                     QKISLIGSENTVQQKIQDFMETYGEVNEIMAISYIYDKDMQLDSYRRFKNVINQINEK
                     NTL"
     gene            78366..79508
                     /locus_tag="RFE25_000078"
     CDS             78366..79508
                     /locus_tag="RFE25_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDU2815188.1"
                     /translation="MEIYADYAATTPVKPEVVDAMMMIYNSHYGNPSSIHAKGRDARK
                     YLDESRRQIAQLLGADTHEIIFTSGATESNNTAIKGIVKANEQLGNHIITSKIEHHSV
                     LHVFEQLEREGFDVTYLDVDDTGAIDLDQLEETITDKTILVSIMFVNNEVGTVQQIYD
                     IQDIIAETNAYFHVDAVQAIGHLDVKFDEFEIDAMSITAHKFGGPKGVGALLVKDHVT
                     LDYPQLGGEQELKRRAGTENLAQIVGMAKALQLAEKNRDDNNIHLMNLKEQFLVKLQE
                     RAIPFELNGSMTDATGHIVNLYFPFVEVEMMLTLLDMAQIYVSSGSACTAGSTQPSHV
                     LDAMFEDEERSNHSIRFSFNELTTENEINAIVAEIHKIYFKFKEES"
     gene            79509..80627
                     /gene="mnmA"
                     /locus_tag="RFE25_000079"
     CDS             79509..80627
                     /gene="mnmA"
                     /locus_tag="RFE25_000079"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDU2815189.1"
                     /translation="MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTD
                     ENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMC
                     NKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQ
                     QQLSKVMFPIGDIEKSEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQP
                     GDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHD
                     ALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEP
                     VRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV"
     gene            81322..81990
                     /locus_tag="RFE25_000080"
     CDS             81322..81990
                     /locus_tag="RFE25_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDU2815190.1"
                     /translation="MIDQQTIYQYIQNGKIEEALQALFGNIEEDPTIIENYINAGIVL
                     ADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQV
                     DCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQL
                     KHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKM
                     KEEE"
     gene            81992..84469
                     /locus_tag="RFE25_000081"
     CDS             81992..84469
                     /locus_tag="RFE25_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDU2815191.1"
                     /translation="MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDT
                     MPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAETFEKEMPQTKEAIISYLSSDLF
                     KGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIM
                     IRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAY
                     NDNERLKAALLYTLEEECIKQGHTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQY
                     LNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIEQSDLQMHIGEIEDA
                     NQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVN
                     DDYPVVLAAPTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDE
                     MSMVDTWLFHQFLSAVPLDAQLIFVGDEDQLPSVGPGQVFKDLIESKAIPRVNLTEVY
                     RQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAVNKGYTM
                     ADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPN
                     DNIFNGDIGVIVGIFWAKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQ
                     GSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLLGDPEAFDIGLKTNGQARLTQ
                     LCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDIN
                     VLTEATMFKIDPMINMGEITPYDFIER"
     gene            84812..87442
                     /gene="alaS"
                     /locus_tag="RFE25_000082"
     CDS             84812..87442
                     /gene="alaS"
                     /locus_tag="RFE25_000082"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDU2815192.1"
                     /translation="MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSG
                     VATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQ
                     EAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWD
                     IGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYT
                     PLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFK
                     VIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVAD
                     IMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAF
                     KLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLK
                     NITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVAD
                     TGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHS
                     ATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKG
                     IDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFK
                     IVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQMKVKSDDQVVEKLTQLQDE
                     EKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSK
                     LQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGG
                     TQPENISKSLSFIKDYIKNL"
     gene            87505..87765
                     /locus_tag="RFE25_000083"
     CDS             87505..87765
                     /locus_tag="RFE25_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDU2815193.1"
                     /translation="MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVG
                     YLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK"
     gene            87769..88197
                     /gene="ruvX"
                     /locus_tag="RFE25_000084"
     CDS             87769..88197
                     /gene="ruvX"
                     /locus_tag="RFE25_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDU2815194.1"
                     /translation="MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELG
                     IDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERL
                     STMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH"
     gene            88212..88520
                     /locus_tag="RFE25_000085"
     CDS             88212..88520
                     /locus_tag="RFE25_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDU2815195.1"
                     /translation="MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKK
                     EYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
                     "
     gene            88805..89443
                     /locus_tag="RFE25_000086"
     CDS             88805..89443
                     /locus_tag="RFE25_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDU2815196.1"
                     /translation="MDDLNKKYLIDLHQHQNSSIEVLREFAEGNEVPIVDRLTLDLIK
                     QLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFEN
                     QVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYH
                     GFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE"
     gene            89446..90369
                     /locus_tag="RFE25_000087"
     CDS             89446..90369
                     /locus_tag="RFE25_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDU2815197.1"
                     /translation="MTELLVTPKSLSHMETLIDLGADAFVIGEQKFGLRLPGEFNRQQ
                     MTEAVALAHKNDKKVYAAVNGLFHNYHLDAVEDYINFLHEIRVDRIIFGDPAVVMYVK
                     AQENPIPLHWNAETLVTNHFQCNYWGKRGASRAVLARELNLDEIINIKENSNVEIEVQ
                     VQGMTCMFQSKRMLLGNYYTFQDRQMKIERRNDEQSLLLYDEERQNNYPVYEDYNGTH
                     IMSPNDICLIEELAPFFEAGIDSFKIDGILQTEEYINVVTEQYRQAIDLYNEDPEIYE
                     DEKFMLIDPIEEIQPDHRPFDEGFLYKQTVY"
     gene            90381..91649
                     /locus_tag="RFE25_000088"
     CDS             90381..91649
                     /locus_tag="RFE25_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDU2815198.1"
                     /translation="MKTIEEIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLG
                     GQEYGLRSNADNFTMEEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKT
                     GATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGA
                     MEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLE
                     VDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATV
                     VSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSK
                     KSPFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNS
                     LDAARHPLQIVQIKVDRPIYPNNMMRKEIG"
     gene            91649..92272
                     /gene="udk"
                     /locus_tag="RFE25_000089"
     CDS             91649..92272
                     /gene="udk"
                     /locus_tag="RFE25_000089"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDU2815199.1"
                     /translation="MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKD
                     QKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFK
                     PKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQY
                     LSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ"
     gene            92300..92776
                     /gene="greA"
                     /locus_tag="RFE25_000090"
     CDS             92300..92776
                     /gene="greA"
                     /locus_tag="RFE25_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDU2815200.1"
                     /translation="MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGD
                     LSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDE
                     EESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ"
     gene            93102..93836
                     /gene="pxpB"
                     /locus_tag="RFE25_000091"
     CDS             93102..93836
                     /gene="pxpB"
                     /locus_tag="RFE25_000091"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDU2815201.1"
                     /translation="MDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQD
                     IVPSYRAVLIYFDEQAITSSKLIENLELNKFNEKNVHAVNQTNRIIKIPVQYGGTYGP
                     DIEEVAKHNRITVEQVIEKHTSKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKI
                     HAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQ
                     KFIQIERDISDGNFNVDDWVVIENVN"
     gene            93826..94836
                     /locus_tag="RFE25_000092"
     CDS             93826..94836
                     /locus_tag="RFE25_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HDU2815202.1"
                     /translation="MSIKILQPGLFSTVQDLGRIGYEHIGFSGAGAMDQFSFKVAQSL
                     INNDGPAIEYTLIGPTIQFNTQNTFVITGGSINASLNNKTISMNSVILAEKGDILKIG
                     AITKGVRGYLTFGHSINVPSIAESYATHTRSSIGGFKGRKLLANDVITVKINNDFKEN
                     IGKTIHLQDDLLPENNIIHILQGPQFEAFSEEARAKIVNHPYLITEQSDRMGYRLEGD
                     SVAPINQADIISEPVALGSVQVPNDGQPIILLNDKQTIGGYTKIATVCKFDLPKLAQM
                     KPKDTIQFKWISFQEAVDKNREQMSLFNEILKSHQKTPIFDTSSLRHTSKKLSTILKG
                     DL"
     gene            94838..95287
                     /locus_tag="RFE25_000093"
     CDS             94838..95287
                     /locus_tag="RFE25_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HDU2815203.1"
                     /translation="MNIEKIEQIIKLVKENDVKKFKYKNFEDEIEIDFTDSNHLAAHS
                     NQSNQSMNNNDLTASKANDNSDVSTNDYHDIKSPMVGTFFLQDSKELTEPIVNVGDKV
                     NKGDIIGYVEAMKVLNEVTTDVAGEITEIVADHGTNVEYDQVLVRIK"
     gene            95301..96662
                     /locus_tag="RFE25_000094"
     CDS             95301..96662
                     /locus_tag="RFE25_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDU2815204.1"
                     /translation="MLRCLIANRGEIAVRIIRACREYGIETVAVYAKGDEQSLHVHLA
                     DQAICIGEANALDSYLNIDRIISAAQITGANAIHPGYGFLSESTKFAQTVEEQGIAFI
                     GPTKKTMEMMGDKITARQTVHHAGVPVIPGSNGAVNHVSEIENLAKDIGYPVVIKAAS
                     GGGGKGIRIVKKAEDLEKAFKEAKSEGKKYFDDDRVYVEAFIPVAKHVEVQVMGDGQD
                     NYVHLGERDCSVQRKNQKLIEESPCAALTEERRQQICNDAVKVARAANYRSAGTIEFL
                     VTDTAHYFIEMNARIQVEHTVTEMRAERDLVAAQLYLLEHNHLPFSQSDIQFNGHVIE
                     ARINAENPEKKFQPTPGKVTALHLPQGFNVRVDSLLYHGYQVSPYYDSLVAKVIVKSH
                     DRASAIDKLKVTLDEMVIDGFSTTADFLYAVLNYPLYRDGDAKDVDIKFLEKHQIVKG
                     VEL"
     gene            96662..97414
                     /gene="pxpA"
                     /locus_tag="RFE25_000095"
     CDS             96662..97414
                     /gene="pxpA"
                     /locus_tag="RFE25_000095"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HDU2815205.1"
                     /translation="MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENV
                     MNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNDEIYNLMIYQLGALQGFCRIHQ
                     LKINHVKPHGALYQMGAKDREIANVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLIT
                     ASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQAD
                     TICVHGDGEHALLFVSKIREILMKEGIDIQSL"
     gene            97427..98656
                     /locus_tag="RFE25_000096"
     CDS             97427..98656
                     /locus_tag="RFE25_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDU2815206.1"
                     /translation="MGRNLKLKKESDFEFTKNHKRLLLGSVFLMATSAIGPAFLTQTA
                     VFTSQFFASFAFAILLSIIIDIGAQINIWRILVVTGLRGQEISNKVVPGLGTVISILI
                     AFGGLAFNIGNIAGAGLGLNAIFGLDVKWGAAITAIFAILIFVSKSGQKIMDVVSMIL
                     GIVMILVVAYVMFVSNPPYGDAFVHTFAPEHPMKLVLPIITLVGGTVGGYITFAGAHR
                     ILDSGIKGKQYLPFVNQSAIAGILTTGIMRTLLFLAVLGVVVTGVTLSSENPPASVFE
                     HAIGPIGKNIFGIVLFAAAMSSVIGSAYTSATFLKTLHKSLNERSNLIVIVFIVISTM
                     IFLFIGKPISLLIIAGAINGWILPITLGAILIASKKKSIVGDYKHPNWMFIFGIVAVL
                     VTILTGIFSFKEVLQLF"
     gene            98945..100165
                     /locus_tag="RFE25_000097"
     CDS             98945..100165
                     /locus_tag="RFE25_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDU2815207.1"
                     /translation="MGYRTLKSIFHEHNESKMKEEYTKRFNSLASFNTNINIIPMENG
                     KKVNDLEYPLFFMVTKNLSKKQELISINSRKIDRALNSLPYAAREQYFNDLLIDELQS
                     TNEIENVFSTKQEIAHALNNQASEFLKFRGLVDQYKEIELNKKIKVDNVRDIRAIYDK
                     LVSNEINEQDKLDGELFRKNFVGVHDGSTNKYIHVGLQPETKIVEYIGEMLTFLKYFD
                     APQPFKIMASHYLFEYIHPFYDGNGRVGRFIIAKLLSDYYDNYTALTFSYVINRNKSK
                     YYKAFMTASNHLNCGDLTEFIDTMLELLIAGQERILDELIPKMDATEKLTLYLTSHYK
                     QIDYEFLYLLSMDKLFGNKRNRLTLIDLENILGVGRVKINNTIKKYDNYLVKIKSRPT
                     IYEISDEFLNSIIK"
     gene            100929..101584
                     /locus_tag="RFE25_000098"
                     /pseudo
     CDS             100929..101584
                     /locus_tag="RFE25_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503564.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
BASE COUNT        36613 a        13873 c        19398 g        31700 t
ORIGIN      
        1 cttcaaactt tcactcatat tactttggaa atttattata aaatagaagt atggatgtat
       61 ttctgaaatg atacattatt aaatagatga gaaagtaaaa gttttgagcc aagtacgcaa
      121 tttaatatta taagttgcat ataaaaaccc ctgttgaact ttagtatatt caacaggggt
      181 aaaacttgtt gttatttatt tgatttagca gcgatacgtt tatatcttaa gtacataaat
      241 gctaaaagta taaaccaaat cggaataaaa taaattgcac gtcttgtatc aacattaata
      301 aataataacc cgaacacaaa aatgaagaat acaaatatta agtagcccat atatttacca
      361 cctaatagtt tgtacgtagc atttttatgt agatctgggt ttttacgact ataattgata
      421 tatgcaatga taatcagacc ccatacaact aaaaataaca ctgtagagat ggtagtcaca
      481 tacgtaaata cttttgtcgc atctgggaaa atatagttta gtaatgctgc cacaagtaat
      541 aatgctgatg aagcaaagat tgcaacatgt ggaacgccat atttattcgt cttagaaaag
      601 ttcggaggtg cttgttgttg acttgataaa ccgaaaagca tacggctatt tgagaatata
      661 ccactgttac atgatgaagc agcagcggtt aatactacaa aattaatcaa gcccgcagca
      721 aacggaattc cgatcaatgc gaataatttt acgaatggac tgttatcagg atcaacttgc
      781 tgccaaggga taatagacat gataaccgct aacgcaccaa cgtaaaatat taaaattcta
      841 atgggtacac tgttaattgc ctttggaatt gttttaactg gatcttttgt ttccccagct
      901 gtaacaccaa tcatttcaat tcctacaaat gagaataatg ccatttggaa agacataaag
      961 aatccagaag cacctttagc gaatatgccg tgttcatata aatttgtgaa actggcatgc
     1021 ccgaattgag ttttaaatgc aaatagaatc atgacgaaac caactactat taaaccaata
     1081 attgtcgcta ttttaatgat agagaaccaa aattctaatt ctccgaaaag tcttgcgcta
     1141 agtaggttga atgacattaa taacagtaca caaaatagtg cacttatcca gtttggaatt
     1201 tctgggaacc aaaagctaac atattttgcc acagccgtta cttcagccat acctgtaata
     1261 atccaacaga accagtatgt ccatccggta acaaatcctg caaaaggccc aatatatgta
     1321 ttggttacat ctgcgaaaga tttaaattca gtattctgta taatgatttc tcctaaacct
     1381 cgcataaaca taaataacat aaatcctata atgatgtatg ttaatagaat tgaagggccg
     1441 gttaatgcaa tcgtttgacc agcacctaag aataagcctg taccaattgc accgccaatt
     1501 gcaattaatt gtatgtggcg attgctcagt tccctttgta atttttcagc cataatacat
     1561 ctcccttaaa tatagatatg tttattatgc acttatattg agatatatac aattattttc
     1621 ggtaaaaatg tgtaaaattc catgttaata tactttggtt tttataatca tatataataa
     1681 ccaattgaaa atttaattct attgtaaaat tcatggatta ttcacatctt gaaaaagctt
     1741 taatggtgct atttgtggct attctgtgac atttacatag atttacaaaa aaattgttgc
     1801 acatataatg ccagttttta tatttcacaa acgaaatgcg tttagctata atattagttg
     1861 aaagccattt cataaagaaa cagtaaaggg gaaatttatc atggcagaat tacaaagagg
     1921 tttagaaggg gttatcgcag cggagactaa aataagttca attattgaaa gtcaattgac
     1981 ttatgccggc tatgatattg atgatctagc tgaaaatgcg caatttgaag aagttatttt
     2041 cctattatgg aactatagat tgccaaacga agaagagctt gctcatctaa aagggaaatt
     2101 aaatcaatac atgacattaa atcctcgtgt gtatacacat tttgaggagt atgttacaga
     2161 tcacgtgcat ccaatgacag cattacgtac gtcattatca tatattgcac atttcgatcc
     2221 tgatgctgaa aatgaatcag atgaaaatcg ttatgaaaga gcaatgcgta tacaggctaa
     2281 agtagcatca ttagttacag cgtttgctcg agtaagacaa gataaagaac cacttaagcc
     2341 taatcctgac ttaagttatg cggcaaactt cctatatatg ttacgtgggg aattaccaac
     2401 agatatagaa gtagaagcct tcaataaagc acttatttta cacgctgatc atgagttgaa
     2461 cgcatctgca tttacagcac gttgtgcggt atcatcattg tcagatatgt actcaggtat
     2521 tgtagcagct gtaggttctc tgaaagggcc attacatggt ggtgcaaacg aacaagttat
     2581 gacgatgtta tctgagattg ggtcaattga aaatgttgat gcttacttag atgaaaaatt
     2641 tgctaataaa gataaagtaa tgggctttgg tcatcgtgta tataaagatg gtgatcctag
     2701 agcgaaatat ttaagagaaa tgagccgtca aattacgaaa gacgctggtc gtgaagaatt
     2761 atttgaaatg tcagtgaaaa tggaaaaacg tatggcagaa gaaaaaggat taattcctaa
     2821 tgttgatttt tatagtgcga gtgtttatca ctgtatggaa atacctcatg acttattcac
     2881 gccaatcttt gctgtaagtc gttctgcagg atggattgct catattttag aacaatataa
     2941 agataataga attatgcgtc ctagagcgaa atatattggc gaaacgaatc gtaagtatat
     3001 cccgcttgaa gaaagaaaat aatcaataca aattaaaaat gaagatgtaa aatttggagg
     3061 taaaataact atgactgcag aaaaaattac tcaaggaact gaaggattaa acgtacctaa
     3121 tgaaccaatt atcccattta ttatcggtga tggaattgga ccggatattt ggaaggcagc
     3181 aagccgagtt atagatgctg ctgttgagaa agcctataat ggcgaaaaac gcattgaatg
     3241 gaaagaagtg ctagctggcc aaaaagcatt tgatacaact ggtgaatggt tacctcaaga
     3301 aacacttgat acaattaaag aatatttaat tgctgttaaa ggacctttaa caacaccaat
     3361 tggtggtggt attagatcat taaatgtggc tttacgccaa gaattagatt tatttacttg
     3421 cttaagaccg gtacgttggt ttaaaggagt accatcacct gttaaacgtc cacaagatgt
     3481 tgatatggtt attttccgtg aaaatactga agacatttat gctggtattg aatttaaaga
     3541 aggtacaaca gaagttaaaa aggtaattga cttcttacaa aacgaaatgg gtgcgacaaa
     3601 cattcgattc ccagaaactt caggtattgg tattaaacca gtttctaaag aaggaactga
     3661 gcgattagtt agagcagcta tacaatatgc tatcgataat aaccgtaaat cagttacttt
     3721 agttcataaa ggtaatatta tgaaatttac agaaggctca tttaagcagt ggggttacga
     3781 tttagcatta tctgaatttg gtgatcaagt attcacttgg caacaatatg acgaaattgt
     3841 tgaaaatgaa ggcagagatg ctgctaatgc tgctcaagaa aaagctgaaa aagaaggcaa
     3901 gattatcatt aaagattcta ttgctgacat tttcttacaa caaattttaa ctcgtccagc
     3961 tgagcatgat gttgtagcaa ctatgaactt gaatggtgac tatatttcag atgctttagc
     4021 tgcacaagtt ggtggtattg gtattgcgcc aggtgcaaac attaattatg aaacaggtca
     4081 tgctattttt gaagcaacac atggtacagc tccaaaatat gcaggtttaa ataaagtgaa
     4141 tccatcttca gtaattttaa gttctgtatt aatgttagaa catttaggat ggcaagaagc
     4201 ggcagataag attacagatt caattgaaga tacaattgct tcaaaagttg ttacttatga
     4261 ctttgcccgt ttaatggatg gtgctgaaga agtttctaca tcagcatttg cagatgaatt
     4321 gattaaaaat ttaaaataag caaaataaaa ttaggtgagt ctagcaactt taattgctag
     4381 gttcgccttt ttaaatgaat tgaagttggc aacaggatag aaataataaa gagtcaccaa
     4441 tgattgatta tgtagtgttt attacacatt agacaaagcg aatttgtaca taagcttagg
     4501 aataaatgag taaaactcat gcataggtag tgggatagaa atgatatttt tacaaaattt
     4561 atttcgttgt cccagagtaa gtcatgcaaa tgatagaagg aaatataaga agtattttat
     4621 ttatatgtaa agtaatgtaa aaaatgtgta aagataatgt gtaggatgtt atttttataa
     4681 atagttcggt tataatgtaa atataattat aagttaggga ggcataccat gtcgcaaaaa
     4741 gtgttggtag tagatgacga acattcaatc gtaacattac ttaaatataa cttagaaaca
     4801 gctggttatg aagttgttgt cgcatttgat ggtgatgagg ctttagaaaa ggtagaaagt
     4861 gaacagccag atttaattat tttagatgtt atgctaccta aaaaagatgg cattgacgta
     4921 tgtaagactg taagaacaaa taaaaattta gtccctatat taatgttaac ggcgaaaaat
     4981 gatgagtttg atcgggtatt aggtttagaa ttaggtgccg atgactatat gactaagcct
     5041 ttttcaccta gagaagttgt tgcccgtgtg aaagccattt taagacgttc tcaatttgta
     5101 aaagaagtag aagagattga cgatgatatt accatcggat cgatacgtat tagacccgat
     5161 tattttgaag tatataagca taatgagtta ttggagctaa caccgaaaga atttgaactc
     5221 ttgctttatt tgatagaaag acaaggcaga gtcattacga gagagcatat gttaaatacg
     5281 gtatggaatt atgaatttgc aggagactca agaattgttg atgtacatat cagtcattta
     5341 agagataaat tagaagataa tcctaagaag ccacaactta ttaaaactgt gcgtggctta
     5401 ggctataaat tggaaagacc taaagaacaa tgatgaagtt tcaccaccgc ttaatgttat
     5461 tgataagcag tatattaatt atcagttttg ttacattagg cattattatt cacgcttcca
     5521 tcacatatgt tttatcagaa aaacacgaac aagctctagc aacagatgca agatcatata
     5581 tttatttagt ccaagataat gagattgata aagttaaaga aattgtaaaa cagcaaaata
     5641 tagatttatt gataactaaa catgataaaa aggtgtttag tagtggcaaa ctgaaagcta
     5701 tcccaaatag tgatagctat attcaaaaaa gggacgtttt tatttttaat aagaaggtta
     5761 acggttatca tgtatggatt aaaggttaca ataacgatat tacagaaatg cattggacgt
     5821 tgtggaaata tcttatattg acatgtttag ttgtactcat ttgtctgtat tttgcaagcc
     5881 gtagttttaa gcgtacatta atccgtccca ttcaagaagt tacttatgca acacaattgt
     5941 tggcaaatgg ttattatcac atacgtgtac ctgaaagtaa tgttgtagaa acgaaagcgc
     6001 tttttgtgtc taccaatgat ttagcacgac gccttcaaaa gcttaataat gagcaaaaaa
     6061 ttcaatccaa ccgtttaaaa acaacgattg aaaatattcc aagtgctatt ttaatgatag
     6121 atcgaaatgg aaaaatcgtt gttgcaaata aagcgtatta tgaacagttc aacatctcgc
     6181 ataatattga acaagtaggc tatcacggct atgttaatac tgaaattgag caattaattt
     6241 tagaaagttt taaagttgaa aaacctattt atgaacaatt ggaagttgca ataaaccaag
     6301 tccatgccaa gtactttgat atttcatgcg ttccgatttt aactaggtct caaaaaagtt
     6361 tgcaagggat tttagttgtg atgcatgata taacaaatct gaaacaactt gaaaatctaa
     6421 gacgtgaatt tgtagcaaat gtttcacatg aattaaaaac acctattact tcaattaagg
     6481 ggtttgctga aacgcttatt gatggtgcaa aaaatgatgc ggaatcatta gacatgtttt
     6541 taaacataat tttaaaagaa tcaaatcgaa tagaatcttt agtaacagat ctgttagatt
     6601 tatcgcatat tgagcaacat acagagttag atacagacta tatgaattta tcagatttaa
     6661 cgcggcgtat tattgataat atgatgactc aagccaatca aaaaaatatt tccattcata
     6721 ctgatattga aaaagatgtc attgttaaag cacaagaaag taaaattgct caagttatca
     6781 cgaatttgtt aacgaatgca attaactatt cttatgaaga tggagatatt aacgttcgtg
     6841 tgtatcgaga tgactttcgt gtcattttcg aagtacaaga ttttggtata ggtattaaat
     6901 tagaagacca acaacgtatt tttgaaagat tttatagagt agataaagca cgaagtagag
     6961 attctggtgg gacaggtctt ggattatcaa ttacaaagca tatagtagag gcccaccaag
     7021 gcaatattga agtgaatagt caagttggca aaggctcaac gttcaaagtt attctaaaag
     7081 attataaaga ataaaaatta aagtggtaac agcgcgtgta tttttcacga agttgttgct
     7141 gcttttttat ttcgttcaaa tctctattgg tattaaatta gagttaatga attggaataa
     7201 attcggttgt caattttgtc attagcatat atcgttttgt aagttataag taatagattg
     7261 ttgtgaatca agcaatttta taatatattt attataataa agaaatttta gtaatgcgct
     7321 taaaatagat gcttaattaa aaagtaataa gttttatttg aacggaaata aatcttaatt
     7381 tgaacacttg aatatacaag tgtaatcatt cgtcatagaa aaagacgagg ggcgatttag
     7441 ataaattgtt gaaagtaata ttaaatacct tgtttatcta atttgattga ggaaacatgc
     7501 ataggtgaaa attagaaata cattaaaaat attgaattaa tttttcgacc tacaagttga
     7561 ggaaaattta actagatttg aggattagca aagtgaaaac aattcaatta cacaagacaa
     7621 ctttgatatt aattgcgata ttattgtttt atacttttat gggtatctta ctaccaatca
     7681 tgcacgatga tttacaatgg tttagcaatt ataatactga tattttaaaa gtaggatttg
     7741 catcacttaa tggtcgctat atcggaaata tctttgaaat tatagctgta catgtaagct
     7801 ggttacgttg gctttcatat ggtctcatta gtatgggcat catttggatg attatgcaca
     7861 ttacacgttg taaagcgtgg acaagctatt atttgttagc attttcttta atgttaattt
     7921 taccaagtgc tatttatgca gatacatatg gctggtttgc aggattttat aattatgcga
     7981 catcaacact aatttcactc tttattattt attattgtat taatgcaatt atatataaag
     8041 aaaagcagcc ggtaagtgtt actgtactat tctatgtttt atgcttcttc ggtcaattat
     8101 ttatggagaa tgtgacatta ttccactgta tcattttaat tttagctttt ctgtatgaat
     8161 ttactgcaaa tcgaacactt aattataaat tattgttttc atttatgatt gctactatag
     8221 gtacaatcat tatgttttcc aatccaaatt atcgcaaaat tttatttgaa ggatcagaat
     8281 atcaacaagt ttcaaataat caaggtatct tttcaaaatt tgcagaaatg atatcaacgt
     8341 cacttccata tggtgtcatt ttcagtcaga ttataatttt aagtatgatt gcagcgctta
     8401 ttatttatct actgcttaga agtgatcggt atgtacattt aacaatatta aagcgtcgta
     8461 tcattatgat aggatttatc actttaccgc tttattattt actattttac aatcagtttt
     8521 tattaaataa aaatacagat attggattgg ttggttttgt gaacgtaatt gtatgtggtt
     8581 actttgcgtt ttcgatattt gtaggtattt atttgtctat taatgatcgt aaaacacaaa
     8641 tcactttata ttccttactt attgcaatat gtgtttcggc gtcgacacta gtcattgtta
     8701 ctccaataga accaggtaat tttttgattg tttatacgat acatgtaatc attttaatta
     8761 ttttattaaa agaatttcgg aaatataagt caatcaatgt taattttatt aaaggtgcat
     8821 cactagtttt agctgtgata tatcttagtg catttattta tgttcattat gaacatgaaa
     8881 aaagagttca gttattaaaa caacaaatta aagatcatcc acgacaagag gtttatacag
     8941 tggaatcatt gccgtttgaa cattatatgc atcatccgtc accaatcaat aaaaattacc
     9001 aagagtggtt taataattat gaagaattac cgaaaatgac caaagttaaa tatattccat
     9061 ttggttcaga cgattcataa cttattctta cctataaaaa tttaaaatag cagcataaaa
     9121 atattaaaaa gtagacataa tcatgaaatg ataatgtgca tctcaaaagt tggactttta
     9181 acctgacttt atggagtgct catcaagaac aatcatgatt atgtcttttt tattttttag
     9241 ctaagtctat ataggcactt gttttatttg aaattaggtc gtgtataaat actctatgag
     9301 atagtttctt taattacgac atcacagtcg aatatgctaa aatatatata aattagttct
     9361 ggaggttaaa attgtgaata aattagtatt aatcgatggt aatagcttaa gttttagagc
     9421 tttttatgca ttacctttgt tatcaaacaa agcaggcatt cataccaatg cagtatatgg
     9481 ttttgcaatg ttactagaga agattttaaa agaagaaaag ccaaatcatt ttttagtagc
     9541 gtttgatgca ggtaaaacaa ctttcagaca tgaaaaatat agtgaatata aaggtggacg
     9601 ccagaaaacg ccgcctgaac taagtgagca atttccttat atacgccaat tattagatgc
     9661 ttatcatatt aaacgttatg aattagataa ctatgaggca gatgatatta tcggaacttt
     9721 aagtaaagaa gcagataaag cgggctttca gacaattatt ataacgggag accgagattt
     9781 aacacaactt gcaacggata atgtaaccat ttattacact aaaaaaggtg ttactgatgt
     9841 tgatcattat acacctgact ttattgcgga aaaatacaac gggttaacac ctaatcaaat
     9901 tattgatatg aaaggattaa tgggagatac ttctgataat ataccaggtg ttgcaggtgt
     9961 tggagagaaa acagcaataa aattgctaaa ccaatttgac acagtagaag gtgtctatga
    10021 acatttagat gaaatttcag gtaaaaagtt aaaagaaaaa cttcaaaata gcaaagaaga
    10081 tgcattaatg agtaaagaat tagcaacgat taatgtagat agtccgattg aagtaaaact
    10141 tgaagatacg ttaatgactc atcaagatga acaacaagaa aaaatcgaat tgtttaagaa
    10201 gttagaattc aaacaattgt tgtctgacat tgatcaatca gcaagcgttg aagatgcaat
    10261 agaaaagaca tttgaaattg aaacgtcttt tgataatatt gattttactt cattgaaaga
    10321 agcggccatc catttcgaat tagacggtgg taactatttg cgaaataata ttttaaaatt
    10381 ctctttattt acaggtgaga aacatattgt aattaatgcg gatgacataa ataattatgc
    10441 cgaactagtt tcatggttag aaaatccgaa tacgaaaaaa gtcgtatatg atgctaaaaa
    10501 aacatatgta gcatcacata gattgggaat tgatattcaa aatatttctt tcgatattat
    10561 gttggccagt tatataattg atccatctcg tacgattagt gatgttcaat cagttgtttc
    10621 attgtacggt caaagttttg tgaaagacga tgtaagtata tatggaaaag gtaagaaatt
    10681 taaggtacct gaagatgatg ttttaaatcc atatgttgct tctattactg atgcaattta
    10741 ctttgcgaaa ccaaatatgg ataaacaatt agaagaatac aatcaggtag aactcttagc
    10801 tgatttagag ctaccgctag ctaagatttt aagtgaaatg gaagaaattg gtatatttac
    10861 agatgttcat gatttagaag aaatggaaaa agaaattcaa gaaaaattag acgtcttgat
    10921 tcgaaatatc catgatgcag ctggtgaaga ttttaatata aattctccta aacaattagg
    10981 tgttgtattg tttgagacat tacaattacc tgttattaaa aagacgaaaa caggatattc
    11041 tactgctgta gatgtcttag agcaattgca aggtgaacat cctatcattg attatatttt
    11101 agaatatcgt caattatcta agttacagtc tacttatgtt gaaggattgc aaaaggtaat
    11161 tagtgatgat caacgtatcc atacacgttt taaccaaact ttagcgcaaa ctggacgttt
    11221 atcaagtgta gatcctaatt tacaaaatat tccggttaga cttgaagaag ggcgtaaaat
    11281 aagaaaagcc tttaaaccaa cttcaaaaga tagcgttata ttatcagcag attattctca
    11341 aattgaattg cgtgtattag cacacattac acaagatgag agtatgaaag aagcatttat
    11401 caacggcgat gatattcata cagcaactgc tatgaaagta tttggtgtag aggctgatca
    11461 agtcgatagt ttaatgcgtc gtcaagcaaa agcggttaac tttggaattg tttatgggat
    11521 aagtgattat ggtttaagtc aaagtttagg tattactcgt aaaaaagcaa aagcattcat
    11581 tgatgattat ttagctagtt tcccaggtgt gaaacaatat atgtctgata ttgtaaaaga
    11641 tgccaaagct ttaggttacg tggaaacatt gctacatcgt cgacgctata ttcctgatat
    11701 tacgagtcgt aactttaatt tacgcggctt tgctgaacgt actgctatga atacgccaat
    11761 acaaggcagt gctgcagata tcattaaact ggcaatggtt aaatttgcac aaaaaatgaa
    11821 agagacaaca tatcaagcta aactattatt acaagtacac gatgaattaa tttttgaagt
    11881 acctaagtca gaagtagatt catttagtga atttgtagaa gagataatgg aaaatgcatt
    11941 gcaattagat gttccattaa aagtagactc aagttatggt gcaacttggt atgatgcaaa
    12001 ataaagtgag gttaatggta tgcccgaatt accagaagta gaacatgtaa aaagaggaat
    12061 tgaaccctac gttataaatc aaaaaattga acacgttata ttttcggata aagtaatcga
    12121 aggtaaagct caaggcaagg aaacaattat aaaaggaatt gaattagata cttttaaaac
    12181 tttatcggaa ggctatacca ttacaaatgt agaacgaaga agtaaatata tcgtttttca
    12241 gctagataat aaacgagaac aacgtacatt aattagtcat ttaggtatgg cgggtggttt
    12301 tttcattgta gatgaacttg aagatattat gatacctaat tatcgtaagc attggcatgt
    12361 tatttttgag ttgtcaaatg acaaaaagtt aatttattca gatatacgtc gttttggaga
    12421 aattagaaat gttgcgtctg tagcatctta tccttcattt ttagaaatag cgcctgaacc
    12481 ttttacaaat gaagcattga cgtattattt aaatcgaatt catcaacagt ctaataagaa
    12541 taaaccaatc aaacaagtga ttttggatca taaagtaatc gcaggttgcg gaaatattta
    12601 cgcatgtgaa gcgttgtttc gtgcaggtgt tttaccagat aaaaaagtaa aagacttaac
    12661 acaccaacaa caagaaatgg ttttttatta tgttagagaa gtactagaag aaggtattaa
    12721 gcatggcggt acaagtattt cagattatcg tcatgctgat ggaaaaactg gtgagatgca
    12781 attgcatctt aatgtatata agcagccggt atgcaaagtg tgtggaagtc aaattgaaac
    12841 aaaaatcatc gcgacaagaa atagtcatta ttgtccagta tgtcaaaaat aaagaaagag
    12901 tgaaattatg ccgaaagtta ttggtctaac aggtggaatc gcctcaggaa aatcaacagt
    12961 atcagaactc ttatccgtat tcggttttaa agtagtagat gctgataaag cagccaggga
    13021 agctgttaaa aaggggagta aaggtttagc tcaagtacga gaagtctttg gtgatgaagc
    13081 aattgatgaa aatggtgaga tgaatcgtcg ttatatgggt gatttagtgt ttaaccatcc
    13141 agaaaaacgc ttagaattaa atgctatcat acatcctatc gtgcgagata ttatggaaga
    13201 agaaaagcaa gaatatttaa aacaaggata taatgtaatc atggatattc cattattatt
    13261 tgaaaatgaa ttggaaaata cagtagacga agtgtgggtt gtatacactt ctgaaagtat
    13321 acaaatggat cgtttaatgc aacgtaataa tctgtcatta gaagatgcga aagcacgtgt
    13381 ctatagccaa atttctattg ataaaaaaag ccgaatggcc gatcatgtta tcgataattt
    13441 aggggataaa cttgaattaa aacaaaacct tgagagattg ttagaagaag aaggttatat
    13501 tgaaaagccg aattacggag aagaagatta atattacact ataaataagt cattacttta
    13561 cgtacgcgtt gatgtatgta agtaatgact attttttata aaaaagataa ataaatcaac
    13621 ggaaaacgct ttcaaaattc atataatatg ctatactaat tccataaagt ataacacata
    13681 aaaatcaagg ggtgctttta atgtcaacga atattgcaat taatggtatg ggtagaattg
    13741 gaagaatggt attacgtatt gcattacaaa ataaaaattt aaatgtagta gcgataaatg
    13801 ctagttatcc acccgaaaca attgcacatt taatcaatta cgatacaaca catggaaaat
    13861 ataatctaaa agttgaaccg attgaaaatg gattgcaagt tggtgatcat aaaattaaat
    13921 tggttgctga tcgcaatcct gaaaacttgc catggaaaga attagatatc gatattgcta
    13981 tagatgcaac tggtaaattt aatcatggtg ataaagccat cgcacatatt aaagcaggtg
    14041 ccaaaaaagt attgttaact ggtccttcaa aaggtggaca tgttcaaatg gtagttaaag
    14101 gcgtaaatga taaccaatta gatatagaag catttgacat ttttagtaat gcttcatgta
    14161 ctactaattg cattggtcca gttgcaaaag ttttaaataa tcagtttgga atagttaatg
    14221 gtttaatgac tactgttcac gctattacaa atgaccaaaa aaatattgat aatccacata
    14281 aagatttaag acgtgcacgt tcatgtaatg aaagcattat tcctacttct actggtgcgg
    14341 cgaaagcttt aaaagaagta ttaccagaat tagaaggtaa attacacggc atggcattac
    14401 gtgtaccaac aaagaatgta tcgctcgttg atttagttgt tgatttagaa aaagaagtaa
    14461 ctgcagaaga agtaaaccaa gcttttgaaa atgcaggttt agaaggtatc atagaagtcg
    14521 aacatcaacc actagtgtct gttgatttta atactaatcc aaattcagct attattgatg
    14581 caaaatcaac aatggtcatg tcagggaata aagtaaaagt tattgcttgg tatgataatg
    14641 aatggggtta ttcaaataga gttgtagatg ttgctgagca aattggagca cttttgacat
    14701 caaaagaaac tgtaagtgca agttaataca attaatttat agcctaactc tgacttcgga
    14761 gttaggtttt ttatttttta atacaataat attgtcatgc aaattactta ataagtaacg
    14821 atataatgtt ttttattgtt tcattatttg gttaaatgaa ttaaattgag ggattctttt
    14881 ttcatctcta gatttatagt ataattaggc ataatcaaaa taaagagggt gatgtaatga
    14941 aatgcccgaa atgtaattct acacaatcta aagttgtaga ttcaaggcat gccgatgaat
    15001 taaatgccat tcgaagacga agagaatgtg aaaattgtgg aacacgtttc actacatttg
    15061 aacatatcga agttagtcag cttatagttg tgaaaaaaga tggcacaaga gagcagtttt
    15121 caagagaaaa aatacttaat ggacttgtgc gttcttgtga gaaacgacca gttagatatc
    15181 aacaacttga agacataaca aacaaggttg aatggcaatt acgagatgaa ggtcatacgg
    15241 aagtgtcttc acgagatata ggtgaacacg ttatgaactt gttaatgcat gttgatcaag
    15301 tttcatatgt tagatttgca tcagtctata aagaatttaa agatgttgat caattgttag
    15361 catcgatgca agggatttta agcgaaaaca aacggagtga tgcttaaatg ggacgacaag
    15421 ccttcgaatt cggcttaaga ccaaaggatc aattcaaagt tatgcaacac tttgatttaa
    15481 atacgaatca tttagaggta ttgaatcgac tgtatacacc gctaattgga acgcaagcag
    15541 tgggtttata tcattttatg actcaattcg ttaaagacag tcataatgaa acattgattc
    15601 tttctcatta tatttttatg aatgaactta aaattaattt actagagttt agacaacaaa
    15661 tggacttact tgaagcgatt ggattgttaa aggcgtttgt caaacatgat gaacaagaaa
    15721 cacaatttgt ttaccaatta attcaaccgc cttcagcaca tttatttttt aatgatccaa
    15781 tgttgtcaat ctttttatat agtgaagtcg agcatcgtcg atttcatgag ttgaagaaat
    15841 actttgagta tcaacaaatt gatttgagtg aatttaaaca ggtaacaaga caatttactg
    15901 atgtttttaa agtgccgtct acaaaaatag atatcgatac aagtgatatt ccgattaatg
    15961 aaccgtacca aggtatcgat ttatcaaatg aatcttttga ctttgaaatg ttgagacaaa
    16021 tgttaggtaa acattttatt agtcaagaca ttgttaccaa agatgcaaag cgtttaatta
    16081 cacaactcgc gactttatat ggtttaacag cagatggcat gaagcatgtt attttaaatt
    16141 caattacaag tggacaacag ttatcctttg aagaaatgcg taaacaagca cgctcgtatt
    16201 atttaatgga acacgaaaat caaatgccta aattacaggt gaaatctcct gctacatcat
    16261 cttcgacggg caaatcttca gaagtgaatc caaagccaca aagtgatgaa tggtttgagt
    16321 tacttgaaca aacgagtcca attgatatgt tagcttcttg gtctgaatca gaaccaacta
    16381 tatcgcaaaa gacaatggtt gaagaattaa ttgaacgtga aaaaatgtct tttggcgtca
    16441 ttaatatttt gttgcaattt gtcatgttaa aagaagatat gaaacttcct aaagcgtata
    16501 ttttggaaat agcatcaaat tggaagaaaa aaggtattaa gacagctaaa gaagcatata
    16561 attacgctaa aaaagttaat caacctaaaa atgagggttc tagcggaaat taccaaaagc
    16621 gtggttcata ctatgggcaa cgtaatcgta tttcaaaaga aaaaacacct aaatggttag
    16681 aaaatagaga taaacctagt gaagaagatt cggctaaaga taatagcgta gatgatcaac
    16741 aattagagca agatcgacaa gcatttctag ataaattatc taaaaaatgg gaggaggaca
    16801 gtcgataatg aagcaattta aaagtataat taacacgtcg caggactttg aaaaaagaat
    16861 agaaaagata aaaaaagaag taatcaatga cccagatgtt aagcaatttt tggaagcgca
    16921 tcgagctgaa ttaacgaatg ctatgattga tgaagactta aatgtgttac aagagtataa
    16981 agatcaacaa aaacattatg acggtcataa atttgctgat tgtccaaatt tcgtaaaggg
    17041 gcatgtgcct gagttatatg ttgataataa ccgaattaaa atacgctatt tacaatgccc
    17101 atgtaaaatc aagtacgacg aagaacgctt tgaagctgag ctaattacat ctcatcatat
    17161 gcaacgagat actttaaatg ccaaattgaa agatatttat atgaatcatc gagaccgtct
    17221 tgatgtagct atggcagcag atgatatttg tacagcaata actaatgggg aacaagtgaa
    17281 aggcctttac ctttatggtc catttgggac aggtaaatct tttattctag gtgcaattgc
    17341 gaatcagctc aaatctaaga aggtacgttc gacaattatt tatttaccgg aatttattag
    17401 aacattaaaa ggtggcttta aagatggttc ttttgaaaag aaattacatc gcgtaagaga
    17461 agcaaacatt ttaatgcttg atgatattgg ggctgaagaa gtgactccat gggtgagaga
    17521 tgaggtaatt ggacctttgc tacactatcg aatggttcat gaattaccaa cattctttag
    17581 ttctaatttt gactatagtg aattggaaca tcatttagcg atgactcgtg atggtgaaga
    17641 gaagactaaa gcagcacgta ttattgaacg tgtcaaatct ttgtcaacac catacttttt
    17701 atcaggagaa aatttcagaa acaattgaat tttaaaatga ttggtgtata atgaatacaa
    17761 atctaaatcg tttaaatgat tgaagacaag atgatctaat caatattaca cagaaagcca
    17821 ttgtttgatg agaatatggt taataaatta gatgattact acttcattta tggtatttgt
    17881 aatgaatacc cggatcaaga ccgttatctt aagcagagat atttaataca taaattgtat
    17941 taaataacta gggtggtacc acgacgatct cgtcccttgt ataggggcgg gattttttgt
    18001 ttttttcaga cataaatgtt tgttggtgtc atatattccc tgtttattgt taataggttt
    18061 aatgttaaaa cgatgattgt tgttcaattt tttaacgagg tcagataaaa gtatttataa
    18121 agcaaatagg agggtttaac atggaacaaa ttaatattca atttccagat ggtaataaaa
    18181 aggcgtttga taaaggtact actactgaag atatagcaca atcaattagt cctggattac
    18241 gtaaaaaagc tgttgccggc aaatttaacg ggcaacttgt agatttaact aaaccgcttg
    18301 aaactgatgg atcaattgaa attgtgacac caggtagtga agaagcgtta gaggtattac
    18361 gtcattctac tgcacattta atggcacacg cgattaaaag gttatatggt aatgttaaat
    18421 ttggtgtagg tcctgtaata gaaggtggat tctactatga cttcgacatt gaccaaaaca
    18481 tctcatctga tgactttgaa caaattgaaa aaacaatgaa acaaatcgtt aacgaaaata
    18541 tgaaaatcga acgaaaagtg gtttcacgag atgaagcgaa agagttattc agcaatgatg
    18601 aatacaaatt agaattaatc gacgcgattc ctgaagatga aaatgtaaca ttatatagtc
    18661 aaggtgattt tactgattta tgtcgtggag ttcacgttcc atcaacagct aaaattaaag
    18721 agtttaaact attatctaca gcaggtgcat actggcgtgg agatagtaac aacaaaatgt
    18781 tacaacgtat atacggtact gctttctttg ataaaaaaga attaaaagca catttacaaa
    18841 tgttagaaga gcgtaaagaa cgtgatcatc gtaaaattgg taaagagtta gaattattca
    18901 caaatagcca attagttggt gctggtttgc cattatggtt acctaacggt gcaacaatta
    18961 gacgtgaaat tgaacgttac attgttgata aagaggtgag catgggttat gaccacgttt
    19021 atacaccagt acttgctaat gttgatttat acaaaacatc tggtcactgg gatcactatc
    19081 aagaagatat gttcccacca atgcagttag atgaaactga atctatggta ttacgtccaa
    19141 tgaactgtcc acatcatatg atgatttatg cgaataaacc acattcatat cgtgaattac
    19201 ctatccgtat cgctgagcta ggaacgatgc atagatatga agcaagtggt gctgtatcag
    19261 gattacaacg tgttcgtggt atgactttaa atgattcaca tatctttgtt cgacctgatc
    19321 aaattaaaga agaattcaaa cgcgttgtaa acatgattat tgatgtgtat aaagactttg
    19381 gtttcgagga ttatagcttt agattaagtt atagagaccc tgaagataaa gaaaagtact
    19441 ttgatgatga tgacatgtgg aataaagctg aaaatatgct taaagaggca gcggatgagc
    19501 ttggcttatc gtacgaagaa gcgattggtg aagcggcatt ctatggtccg aaactagatg
    19561 ttcaagttaa aacagcgatg ggtaaagaag agacattatc aacagcacaa cttgatttct
    19621 tattaccaga acgttttgat ttaacttata ttggtcaaga tggtgaacat catcgtccag
    19681 ttgttattca tcgtggtgtt gtatcaacaa tggaacgatt tgtagcattt ttaactgaag
    19741 aaactaaagg tgcattccca acttggttag cgccaaaaca agttcaaatc attccagtta
    19801 acgttgattt acattatgat tatgcgcgcc aattgcaaga tgaattgaaa tctcaaggtg
    19861 ttcgtgtaag tattgatgac cgtaatgaaa aaatgggtta taaaatcaga gaagctcaaa
    19921 tgcaaaaaat accttatcaa atcgtagttg gggataagga agttgaaaat aatcaagtga
    19981 atgtgcgtca atatggatcg caagaccaag aaacagttga aaaagatgaa tttatctgga
    20041 atctagttga tgaaattcgt ttgaaaaaac atagatagac agttgtcgca ataaaatgct
    20101 ttaaaacttt tattgcgtat caagttttac agggttgatt atgcgtgatg aatcctgtat
    20161 attacaagtt agttaaaata ttaaattgag ttagaggttg catgtttaat tagtaacttg
    20221 tcagaagtat ttatggtaca taagttgaac aagtgaaagg taaagatgcc gaaatagata
    20281 taaaccataa attatatcta ttgggacagt tttcgaatag gaactgtact gtcacagaat
    20341 gtgatgtgct accttatata gataattgcc aaagtggttg catatcttaa aggtatgtag
    20401 ccactttttt acttttaata tcactatgtt ctgtaaaaaa gggtatgaaa gtgaataaag
    20461 gttatttatt tcttggcctc taaaacatgg aaagggagct tatatgtcaa aagttcaaaa
    20521 tgaaagtaac aatgttgtca aaaggggact taaagatcgt catatttcta tgattgcgat
    20581 tgggggttgt attggtacag gtttatttgt aacttctggt ggagcaattc atgatgcagg
    20641 tgctttgggt gcattaatag gatacgcaat tatcggaata atggtatttt tcttaatgac
    20701 gtcacttggt gaaatggcta cgtatttacc agtatcaggt tcatttagta catatgctac
    20761 aagatttgtt gatccatctt tagggtttgc gcttggttgg aactattggt ttaactgggt
    20821 agtaactgta gcagcagata ttacgattgc agcacaagtc attcaatatt ggacaccatt
    20881 gcaaggcata cccgcttggg catggagtgc gttgttttta gttataattt ttagtctgaa
    20941 ttcgttatca gttcgcgtct atggtgaaag tgaatactgg ttggcattga taaaagtgat
    21001 tacagttatt gttttcattg caattggttt attaacgatt gtaggaatca tgggtggtca
    21061 tgttgtagga tttgaaatat ttaataaagg tgaaggtcct attcttggtg gcaacttagg
    21121 aggaagtttg ttatcaattc taggtgtatt cttaatcgct ggtttctcat tccaaggtac
    21181 tgagttaatt ggtattacgg ctggtgaatc agaaaatcct gaacgtgctg tgccgaaagc
    21241 aattaaacaa gtattctgga gaattttatt attttacatt ttagccattt ttgttatcgg
    21301 tatgttaatt ccttatgata gtagtgcatt aatgggtggt agtgataatg tagcaacgtc
    21361 tccattcaca ttagtgttta aaaatgctgg atttgcgttt gcagcatcat ttatgaatgc
    21421 agtcatttta acgtctgtgt tatcagcagg taactcaggt atgtatgctt caacccgaat
    21481 gctatattca atgagtaaag ataaattagc gtttgaagca tttggtaaaa caaataaaaa
    21541 cggtgtgcca tatatgtcgt tactcgttac agcaatcatt gtagtgatta ttttcgtatt
    21601 acaaagcctt acaaaaggtg catacgaata tatcgttgca gcaagtggtt taactggttt
    21661 tattgcttgg gtaggtatag cagtaagtca ttatcgattt agaagagcat ttgataaaca
    21721 aaattatgac aaatctaaat taaaatatac tgctaaatta ttcccattcg gaccattatt
    21781 tgctggcttt ttatgtattg tagtaattat tggtcaagat gttgacttta ttaaaacagg
    21841 agattttaat tttagtcgct tcttaattac gtatatggga attccagtat ttttagcatt
    21901 ctttatttat cataagcttc gatataaaac gaaaaaaatt ccattagaac aagtagattt
    21961 acgtcaagac gtgtcaatgg atgaaataaa aggttaaaat aaaaataatt acagttatag
    22021 tgttgactta aatgtgaatt gttgatatga ttaacaacgt tgaatacgaa acgaaccaag
    22081 tagaagcacc cgcttctcac ctgtagcgac gcataaagca gttggcaggt taatcacatt
    22141 acacataact gtgtataagg aagagcgggt attttatacc tgctcttcct ttttgcttgg
    22201 tgcaaatttc gtaaaaattt tggaggtgtc aaccatagca aaagatcaaa ctcaaatcaa
    22261 tgacaaaatt cgtgcaaaag aattacgttt aatcggtcaa gatggtgaac aaattggtgt
    22321 taaatcaaag cgtgaagctt tagaaatggc tgaacgtgta gatttagact tagtggtcgt
    22381 tgcaccgaat gcgaaaccac cagttgcaag aattatggat tacggtaaat tcaaattcga
    22441 acaacagaaa aaagaaaaag aaatgaaaaa gaaacaaaaa attatcaatg ttaaagaaat
    22501 tcgtttaagt ccaacaattg aggaacatga tttccaaact aagttgaaaa acggacgtaa
    22561 attcttaact aaaggcgata aatgtaaagt atctattcgt ttcagagggc gtgccattac
    22621 gcataaggaa attggtcaac gtgtgctaga aaaatatgca gatgaatgca aagatatagc
    22681 aacagttgaa caaaaaccta aaatggacgg gcgtcaaatg tttatcatgt tagcgccaac
    22741 agctgaaaaa taattaaagc tattacagga ggacttatat tatgccaaaa atgaaaactc
    22801 accgcggagc agctaaacgt gttaaaagaa ctgcttcagg tcaattaaaa cgttcaagag
    22861 ctttcacatc tcacttattc gcaaacaaga gcactaaaca aaaacgtcaa ttacgtaaag
    22921 ctagattagt gtctaagagc gatatgaaac gtgtaaaaca attattagca tacaaaaaat
    22981 aagaacaaat acagaaatcg gtaggaatta cctaaggagg aattttttat gccacgagtt
    23041 aaaggtggaa cagtaacaag agcgcgtcgt aaaaaaacga ttaaattagc taaaggttac
    23101 ttcggttcaa aacatacatt atacaaagta gctaagcaac aagtaatgaa atcaggtcaa
    23161 tatgctttcc gtgaccgtcg tcaacgtaaa cgtgacttcc gtaaattatg gattacacgt
    23221 atcaacgcag cagctcgtca acatgaaatg agctactcac gtttaatgaa cggtttgaaa
    23281 aaagctggta tcgacattaa ccgtaaaatg ttatcagaaa tcgcaatttc tgacgaaaaa
    23341 gcatttgctc aattagtaac taaagctaaa gatgctttaa aataataaca cttataaaaa
    23401 agagatggca ttgtcatctc ttttttattt tttaaaaagc aaaatgccac atttaatcgc
    23461 taaaatatga catatttgct aaaatgcatt taagagaaca aacattaaag tgaggagttt
    23521 tatacgatgt ctaaatttga tgaacaaatc attgtagtac ctagagaaat tatttttaat
    23581 aatgaaaaga atactttcaa tgggttttta aataagaata aaccagaagg tcaaaatatt
    23641 tttgatgcgc taagtcaata tgaagttaag cgacgcggcg atatggaaga ggatccatca
    23701 tataaacaac tcatttctta ttgtttactt gaaaatgagc atggcgagat attagtgtat
    23761 gaacgattat ctggcggtgg agaagctcga ttgcatggac aatcttcaat aggtgtaggc
    23821 ggtcatatga atgatgttcc aggagcagaa tctattaacg aagtattgag agttaatgca
    23881 cagagagaat tagaagaaga agtaggttta agtgagcaag attcacaaaa tatggaatat
    23941 atcggtttta ttaatgacga taataatgaa gtgggcaagg tacatattgg tgttgtattt
    24001 aaaatcactg taagtacgaa tgatgtagaa gctaaagaaa cagatacttt acgaataaaa
    24061 tgggttgaaa aaggcaacat agagtcatat gatgatttcg aaacgtggag cgcattaatc
    24121 cttcaagatt tataatcaaa cgaggtgaca tatatgtcag atattattca gtttcctaac
    24181 tcttcgaaaa agttatataa agatataaaa cgtgctgaac aagaccaaaa ctatgacctg
    24241 atgtatgaat atattgtgca atatgaacgt caatttgaac tcactgaaga aatagcaatg
    24301 atgaaatgcc gtatgttata tgagacgggg tcatttcttg aattaagaga agaaacaatt
    24361 gtcttattga aaactggcat acaacaatat gatgcattga tgatttatta cgtgaaaagt
    24421 ttgattggtt tgggacaata ttttgaagcg gtagaagtaa ttcatcaaat tattgatgaa
    24481 gtcaaagatc acaaaacaag aatggcatta catcctctta aagaatttgc taagtcaaaa
    24541 ttaattgaag atgaaaaacg attgactcag tcattaactg attttgatac gttatcaatg
    24601 agggaacaga cgcacttgat tttgaagtta atagacaatg gtcattttca atttcaagaa
    24661 acggtattat atatattaaa atctaatacg tacagttata acctcattag tttaatgatt
    24721 gagtatttaa ggtttgcaaa ttgtacacaa gaactgacaa ttgaaaagta tggtatggat
    24781 gtaacttttg taccagctaa tttaaatggg ctagaacata caacactgaa agaaaaagtt
    24841 atacctaacg ttatggaaac attaaatgat ggtgcattac atatcgctga agaagcacac
    24901 catattatga ataatcactc tatcatgatt tatccaattg atattgaaac tttgtttgaa
    24961 acgaataaat ggattaatgc atacgaatgt tatttcaaaa atatgttagg acttaaatgt
    25021 gaattacaaa gtatcgatgc atttaatttt attcagcaat tagatttgaa taataatagt
    25081 taaattgttg caaaataata ctcagcattt taatatagtt ttgacgaaaa aagttgattt
    25141 acaaatatat aaacgttgtg atttcaatgt ttgtataggg aatagaccta tgatataata
    25201 gggaagttga aaaaataaat tagttaatca tggaggtata tatacatgac agcaacttgg
    25261 gaaaaaaagg aaggtaacga aggtttatta actgttactg ttcctgcaga aaaagtaaac
    25321 aaagcgttag atcaagcatt caaaaaagtg gttaaacaaa ttaacgtacc tggattccgt
    25381 aaaggtaaag tgccacgtcc aatttttgaa caacgctttg gtgtagaagc attatatcaa
    25441 gatgctatcg acattttatt accagatgct tatggtgaag caattgacga aactgatatt
    25501 aaaccagttg cacaaccaga agtaagtgtt actcaaattg aaaaaggtaa agatttcatt
    25561 tttgaagcaa cagttacagt tgagccagaa gttaaattag gagactataa aggtcttgaa
    25621 attgaaaaac aagaaactga attatctgat gatgagttac aagaagcgat tgaccacagc
    25681 ttaggacatt tagctgaaat ggtagttaaa gaagatggtg ttgttgaaaa tggcgacaca
    25741 gttaacattg actttagtgg ttcagttgac ggagaagaat tcgaaggtgg acaagctgaa
    25801 ggttacgatt tagaaatcgg ttcaggttca ttcatacctg gtttcgaaga gcaattagaa
    25861 ggtatgaaag ttgacgaaga aaaagatgtt gtcgtaacat tcccagaaga ataccatgct
    25921 gaagaattag ctggtaaaga agcaactttc aaaacaaaag ttaacgaaat taaatttaaa
    25981 gaagttccag aattaacaga tgaaattgct aatgaattag atgcagaagc aaatacagta
    26041 gacgagtaca aagaaaactt acgtaaacgt ttagctgaac aaaaagctac agatgctgaa
    26101 aatgttgaaa aagaagaagc gattacaaaa gctactgata atacaacaat cgatattcct
    26161 gaagcaatgg ttaatactga attagatcgt atggtgtctg aatttgcaca aagaattcaa
    26221 caacaaggtt tagatttaca aacgtacttc caaatctcag gtcaagatga aactcaatta
    26281 agagagcaaa tgaaagacga tgcagaacaa cgtgttaaaa ctaacttaac tttaactgcg
    26341 atcgctgaag ctgaaaaaat cgaagctact gatgaagata tcgataaaga attagaaaaa
    26401 atgagtaaac aatttaatat ctcagttgaa gatatcaaaa atactttagg taatactgat
    26461 atcattaaaa atgatgttcg tatccaaaaa gttatcgatt tattaagaga taacgcaaag
    26521 ttcgttgaag gaactaaaga agattaatct tcattaaata ttaaattaca aaaatgagta
    26581 gcagatgcat agcttatgta tctgctacta ttctttaagc aaaaagtttg tatgttaata
    26641 tgttgcattg taatatccaa tctagtatag tctttaacga ataggggtgt aaaaagaatg
    26701 tttaaattca atgaagatga agaaaatttg aaatgctctt tctgcggaaa agaccaagat
    26761 caagtaaaaa aacttgtagc aggaagtggt gtatatattt gtaatgagtg tattgaatta
    26821 tgctcagaaa tcgtcgaaga agaattagct caaaacactt ctgaagcgat gacagaatta
    26881 cctactccta aagaaattat ggatcattta aacgaatatg ttattggtca agaaaaagct
    26941 aaaaaatctt tagctgtagc tgtttataac cactataagc gtattcaaca attaggacca
    27001 aaagaagatg atgttgaatt acaaaaaagt aacattgcat taattgggcc aacaggtagt
    27061 ggtaaaacat tattagctca aacattagcc aagacgttga atgtaccatt tgcaattgca
    27121 gatgcgacaa gtttaactga agctggttat gtaggcgatg atgttgaaaa tatcttgttg
    27181 agattaattc aagcagctga ctttgacatt gataaagccg aaaaaggtat tatttatgta
    27241 gatgaaattg ataaaattgc acgtaaatct gaaaacacat ctataacacg tgacgtttca
    27301 ggtgaaggtg ttcaacaagc attgcttaaa atcttagaag gtacgactgc aagtgttccg
    27361 ccacaaggtg gacgcaaaca tccaaaccaa gaaatgattc aaattgatac aacaaatatc
    27421 ttatttattc ttggtggtgc ctttgatggt attgaagaag tgattaagcg ccgtcttggt
    27481 gaaaaagtta ttggtttctc aagcaatgaa gctgataaat atgacgaaca agcattatta
    27541 gcacaaattc gcccagaaga tttgcaagcc tatggtttga ttcctgaatt tatcggacgt
    27601 gtgccaattg tagctaattt agaaacatta gatgtaactg cgttgaaaaa catcttaacg
    27661 caacctaaaa atgcacttgt gaaacaatat actaaaatgc tggaattaga tgatgtggat
    27721 ttagagttca ctgaagaagc tttatcagca attagtgaaa aagcaattga aagaaaaaca
    27781 ggtgcgcgtg gtttacgttc aatcatagaa gaatcgttaa tcgatattat gtttgatgtg
    27841 ccttctaacg aaaatgtaac gaaggtagtt attacagcac aaacaattaa tgaagaaact
    27901 gaaccagaac tatacgacgc agaaggcaat ttaattaata atagtaaaac atcagcttaa
    27961 tcattgatgt gttataaaag tgaaaagctc caatcaaagt tgacgctcaa atagtttaac
    28021 tttgatcgga gcttttttat aatgtatacc gaaaggttca aatattatat aatggtagag
    28081 ttgaaagaga atataaaaaa gtgaggatat aaaatgaaag ttaatcctaa taatattgaa
    28141 ttaatcatta gtgcagtaaa agaagaacaa tatccagaaa cagaattgtc tgaagttgca
    28201 ctgagcggtc gatctaatgt aggtaagtct acatttatca atagtatgat tggcagaaaa
    28261 aatatggcac gtacatcaca gcaacccggc aaaacgcaaa cgttaaattt ttataatata
    28321 gatgaacaac ttatttttgt ggatgttcca gggtatggat atgctaaagt aagtaaaaca
    28381 caacgtgaaa aatttgggaa aatgattgag gaatatataa ctaagagaga gaatttgcaa
    28441 ttagttattc aattagttga tttaagacat gatccaacac aagatgatat cttaatgtac
    28501 aattatttga aacattttga tattcctact ttagttatat gcactaaaga agacaaaatt
    28561 ccaaaaggta aagttcaaaa gcatattaaa aatattaaga cacaattaga tatggaccca
    28621 gacgatacaa ttgtaagtta ttcatcaatt caaaataata aacaacaaca aatatggaat
    28681 ttaattgaac cgtatatttc atagtttttg tacgacaaaa cttatacaaa aattttaaaa
    28741 ataatgtaag cacgaaactt ttaattagta cacaattgat aacatttttc aacgttcatc
    28801 attttgtcaa aaactcaaaa gtaaattaga aagattataa tttatttaag catcgtactt
    28861 aattggattt taaattatgt tataatattt gtattgttag tatatatggg ggcgtttcaa
    28921 atgcatttta ttgcaattag tataaatcat cgcacagctg atgttgcact aagagagcaa
    28981 gttgctttta gagatgatgc cttacgaatt gcccatgaag atttatatga aactaaatct
    29041 attttagaaa atgtcatatt atcaacatgt aatcgaactg aagtatatgc tgttgttgat
    29101 caaattcaca caggtcgtta ctatattcaa cgatttctag ctcgtgcatt tggatttgaa
    29161 gtagatgata ttaaagcaat gtcagaagta aaagtggggg acgaagcagt agaacattta
    29221 ttgcgtgtca cttctggttt agattcaatc gtacttggag aaactcaaat tttaggtcaa
    29281 ataagagatg catttttctt agcgcaaagc acaggtacga caggaacaat ttttaatcat
    29341 ctatttaaac aggcaattac ttttgcaaaa agagcacata atgaaacaga tatagctgat
    29401 aatgctgtaa gtgtgtctta tgctgcggtc gagttggcga aaaaagtatt tggcaaattg
    29461 aaaagtaagc aagctatcat tattggtgca ggggaaatga gtgaattatc actattaaat
    29521 cttcttggtt ctggaattac tgatattaca gtagtaaata gaacaattga aaatgctatg
    29581 aaattagcag caaagcatca agtgaaatat gatgaactat catcattacc aaatttactt
    29641 gaaagtgcag atattgtgat tagttcaacg agtgcacaat cttatatcat tacaaatgaa
    29701 atgatagaaa gaattgcaga aaatagaaag caagattcac tagtattgat tgatattgca
    29761 gttcctcgag atattgaacc tggtattagt gccatcacaa acatctttaa ttatgatgtt
    29821 gatgacttaa aaggtttagt tgatgcaaac ttacgtgagc gacaattagc ggctgcaaca
    29881 atttcggaac aaattcctgc agaaatacat gcacacaatg agtggattag tatgttgggt
    29941 gttgttccag tgattagagc tttacgtgaa aaagctatgg caattcaagc agaaacgatg
    30001 gacagtattg atcgtaaatt gccagggtta agcgaaagag aacgtaaaat tatatctaaa
    30061 catacaaaaa gtatcatcaa tcaaatgttg aaagatccta ttaaacaggc caaagaatta
    30121 agtagtgata agaaaagtaa tgaaaaatta gagctatttc aaaatatatt tgatatcgaa
    30181 gctgaatgtc ctcatgagca agcgaagcaa caaaaagaaa gcaaggtcaa ggaaatttca
    30241 gcgcgacgta tctttagttt tgaataagca tattaatatg gtgataatat gcaagaaaac
    30301 ctgtttattc gattcaatga aattatatta ttaatatact taatcagtat catttgctat
    30361 ttttatgatt ttgtccaaaa aagtcataag attagaagtt taggcatata tttattgggg
    30421 attgtttggg ttttacaaac aatctcttta tctattttta ttatacaaac tagacatatt
    30481 ccattagggt ctatttcaga tgtattctat actttaagtt ggctgattat ttcaatctct
    30541 ttaattctta accttatcaa agtattgaat ttctctgtgt ttttcttgaa tttaataggg
    30601 ttaacacttt tagggatgaa tacatttcaa ccgacacatt atactaataa ggttcagaaa
    30661 attgctgttg tagacgagtt actgttagtc catatcggtc tagctgtgtt aagttatgtc
    30721 ttctttgcct tagcttttgt caatgcatta ctgtatatca tgcaataccg taatttgaag
    30781 gaaaaacgtt ttgatcaaaa atactttaga ataggtagcg ttgctacact tgaatcaatt
    30841 gtgttttact caacgttaag tgggtggata attctcatat ttagtattat tttaggtaca
    30901 cagtggggtg taatttcagt tggtgaacgt atattcattg acccgaaggt aatactctct
    30961 tcaattatta cagtattata tggaagttat atattgctta gaatcaacaa atggttgaat
    31021 tcaaggtatt taatatacta taacattatt ttattttgct taaatatgat taatttattt
    31081 tttgcaacac attttgtgaa ttgagaaaat aatctagagc aatccgttcc taggaggaat
    31141 tgaacatgcg taaattagtc gttggctcca gaagaagtaa attagcttta acacaaagcc
    31201 agcaatttat taataaatta aaagctgtcg agccaaatct agaaattgaa attaaagaaa
    31261 ttgtcacgaa aggcgatcgt atagtagata aacaattgtc taaagtcgga ggcaaaggct
    31321 tatttgttaa agaaatacaa catgaacttt ttgaaaaaaa tatcgatatg gcaatacact
    31381 cgcttaaaga cgtaccaagt gtaattccgg aaggtttaac attaggttgt atccctgata
    31441 gagaattacc ttttgatgcg tatatttcta aaacacatac accactatcc caattgccag
    31501 aaggcagtat tattggtact agttcattac gtcgtggtgc acaaatatta tctaagtatc
    31561 ctaatttaga gattaaatgg attagaggta atatagatac acgattagaa aagttacaaa
    31621 ctgaagatta tgatgcgatt attttagctg cagctggttt aagaagaatg ggctggtcag
    31681 atgatattgt aacatcttat cttgatagag atacattgtt acctgcaatc ggacaaggtg
    31741 ctttagggat agaatgtcgt agtgacgatg aagaactatt aacattatta agcaaagtac
    31801 ataatgatga ggttgcaaaa tgtgtgactg ctgaacgaac gtttttagca gaaatggatg
    31861 gtagttgtca ggtgccaatc gcaggatatg ctacaatctc agatcaaaaa gaaatcgaat
    31921 ttacaggttt aattatgacc ccagatggta aagaacgatt tgaatataca atgaacggaa
    31981 cagatccggt tgagttaggc aaaacagtga gtaacaaatt aaaagagcaa ggtgcttatg
    32041 aaattataaa acgcttaaat gaacaacatt aaataatgga gtgacgttta aatatgaagc
    32101 cagttgtagt tatgacacaa acaaatgaca tgcaaagtga tttagtatca attattcaca
    32161 aaccctttat tgatataaag ccactaaatt ttgatattca tttgttaaat caacgctatg
    32221 actggcttat tttttcatct aaaaatgctg tgaaattctt ttataaatat ctaaaaggaa
    32281 ttaatgttga taacattgct gtgataggaa gtaagacagc gcaatattgt gaatcacttg
    32341 gcattcgagt tgattttatg ccaaacgact tttctcaaga aggattttta aaatcattta
    32401 atcaaactaa ccaaaaaata cttttgcctt cgagtgaatt ggcgagacca ttgttattag
    32461 cagcgttatc taaagataat gaagttgtta aaatagattt atatacttca gtgcctaaca
    32521 aacaaaatat acaagatgtt aaagaaatga tagaacatca acaaatcgat gcattaacat
    32581 tttcaagttc gtcggcagta cgttattatt ttaatgaagg atttgtacca aaattcaagt
    32641 cgtattttgc tattggagaa caaacagcac ggaccattaa aacatatcaa caaccagtaa
    32701 caattgcaga aattcaaaca ctcgaatcac taattgaaaa gattttagaa agtaggggct
    32761 aaaaatgaaa tttgatagac atagaagatt gagatcatca gcgacaatga gagatatggt
    32821 tagagagaat catgtaagaa aagaagattt aatatatcca atttttgtag ttgaaaaaga
    32881 cgatgtgaaa aaagaaatta agtcattgcc aggtgtatac caaatcagtt tgaatttact
    32941 tgaaagtgaa ttaaaagaag cttatgactt aggcatacgt gccattatgt ttttcggtgt
    33001 tccaaactca aaagatgata taggtactgg tgcatacatt cacgatggtg ttattcaaca
    33061 ggcaacacgt attgctaaaa aaatgtatga tgacttatta attgttgcag acacttgttt
    33121 atgtgaatat actgatcatg gtcattgtgg cgtgattgat gaccatacac atgacgttga
    33181 caatgataaa tcattgccac tacttgttaa aacagcaatt tctcaagtgg aagctggtgc
    33241 tgatattatt gcgccaagta atatgatgga tggttttgtt gctgaaattc gtcgtggatt
    33301 agatgaagcc ggctattaca atattcctat aatgagttat ggtgtcaagt atgcatcaag
    33361 tttctttgga ccttttagag atgcagcaga ttcagcgcca tcatttgggg atagaaaaac
    33421 gtatcagatg gaccctgcta accgtttgga agcacttcgt gaattagaaa gtgatcttaa
    33481 agaagggtgc gacatgatga ttgttaaacc tgctctaagt tatttagaca tagttcgaga
    33541 tgttaaaaat catacgaatg ttccagttgt tgcatataat gtgagtggag aatatagtat
    33601 gactaaagca gcggcacaaa atggttggat agatgaagaa cgtgtcgtta tggaacaaat
    33661 ggtttcaatg aaacgtgcag gtgctgatat gattattacg tattttgcaa aggacatttg
    33721 tcgctattta gataaataag gttttatatg tatgattttc cataaactat aggaggaatt
    33781 tactttatga gatatacgaa atcagaagaa gcaatgaagg ttgctgaaac tttaatgcct
    33841 ggtggtgtaa atagtccagt acgcgcattt aaatcagtag atacaccagc aatttttatg
    33901 gatcacggta aaggctcaaa aatttatgat atcgatggta acgagtatat cgactatgta
    33961 ctaagttggg ggccgcttat tttaggacat agagaccctc aagttattag tcatttacat
    34021 gaagcaattg ataaaggtac aagttttggt gcatcaacat tacttgaaaa taaattggcg
    34081 cagctcgtta ttgaccgagt accttcaata gaaaaagtgc gtatggtgtc atctggtaca
    34141 gaagctacat tggatacttt aagattagca cgtggttata ctggcagaaa taaaattgtg
    34201 aaatttgaag gttgctatca tggtcatagt gattcgttat taatcaaagc tggttctggg
    34261 gtggcaacat taggattgcc ggattctcct ggtgtgcctg aaggtattgc taaaaataca
    34321 attacagttc catacaatga tttagatgca cttaaaatcg ctttcgaaaa atttggagac
    34381 gatattgctg gtgtaatcgt agaacctgtt gctggtaata tgggtgtcgt accaccgatt
    34441 gaaggttttt tacagggatt aagagatatt acgactgaat acggcgcatt gctaattttc
    34501 gatgaagtaa tgactggttt cagagtcggt tatcattgtg cacaaggtta ctttggtgtg
    34561 acaccagatt taacttgctt aggaaaagtt atcggtggag gactacctgt aggtgctttt
    34621 ggtggtaaaa aagaaatcat ggatcatata gcaccattag gaaatattta tcaagcgggt
    34681 acgttatcag gaaatcctct tgcaatgaca agtggttatg aaacgttaag ccaattaacg
    34741 ccagagacat atgagtattt taatatgtta ggcgatatac ttgaagacgg tttaaagcgt
    34801 gtatttgcta aacacaatgt accaataact gtaaatagag caggttcaat gattggttat
    34861 ttcttaaatg aaggacctgt aactaatttt gaacaagcga ataaaagtga tttgaaatta
    34921 tttgcagaaa tgtatcgaga aatggcaaaa gaaggtgtgt ttttaccacc atctcaattt
    34981 gaaggtacat tcttatctac ggcacacacg aaagaagata ttgaaaaaac gattcaagca
    35041 tttgatacgg ctttaagtcg tattgtaaaa taaatatacg gacaaattga gagcctgaac
    35101 tttgttcagg ctctttttaa atgtatatca ggcatgggcg gcgacttgat agtgaaagtc
    35161 catatatgct ttgtagtcaa aactgctagc ggatattgtt atcttaacaa acgtgaagct
    35221 caagcagcaa tttagtcatt ttatttttta ttgaaagaag tggaaaacat gacaatgata
    35281 tatagaaata atttcattgt gttcgtttta tcatttttta ttagtattat attgtattca
    35341 tcgcacgtat tactcccatt tatgtttggt cctattatcg catcaatcat ttgtgtgaaa
    35401 gttttcaaac ttgatattaa atggccattc ttacttagtg aattagggat tgtactatta
    35461 ggggtgcaaa tcggatcaac gtttacgaaa aatgtcgtta tggatattaa aaacaattgg
    35521 ctttcgatta ttgttgtatc tatttcgata ttattaattg caatagtaat ggcatttatt
    35581 tttaaaaaaa ttgcacgtat taatacagaa acagctattt taagtgttat accaggagca
    35641 ctaacacaaa tgctggtcat ggctgaacaa gacaaacgtg ctaatttgtt agttgttagc
    35701 ttaacgcaaa catcacgaat tatatttgtt gttgttttag taccgttcat ttcatatttt
    35761 tttcatgatg gtaacatgca tgcgaatgga aagttaacaa aagtcttgcc tttatcacaa
    35821 gtattaaaca tagggcaaat agttatttta gcgatagcta tctttatagt ttatctaatt
    35881 atgtctaaaa taaagtttcc aacatttcaa ttattagcac cactcattgt attaattgtt
    35941 tggaattttt ctacaggttt aacatttaca ctagatcatt ggttgttgaa catggcacaa
    36001 ctaatatata tgattagaat tggagttcaa attgcgcatt tattgtcaga tttaaaaggt
    36061 agactagcaa tcgcaattac aattcaaaat attatgttga taattggtgc gctaatcatg
    36121 gtttatatca tacatttctt tgataataat cctattaatg aattgtttct tggtgcagca
    36181 ccaggagggg ttaatcagat agttttagtt gcattagcta ctggtgccga tgttgctatg
    36241 attacgagtt atcatatttt ccgaatcttt ttcatcctat ttattattgc accaggaatt
    36301 aattactttt taaaatatcg ttcgaataag cgtgaagatt agaaactatc atccatttaa
    36361 gttgaattat gcttaggata gaattcatta ttaaggttta agcaaaggtt gtacatctat
    36421 ttttagatta agatatctaa tattagcagt gcattaactt ggaactttaa cttatgattt
    36481 gaataaattt tcacatcaaa aaacgagaca gtctattagt taaaaataga tgatgtctcg
    36541 tttactttat gatgctatag caaattaatt gtgtttaggc tttgatggac aatcttttaa
    36601 atgtgcatca tataaaccag ctgcttctaa aaacgaaaat actgttactg gacctaaaaa
    36661 tttaaacccg tattgtttta aatctttaga tagttgtgtt gcagtatcat caactgtgat
    36721 acgatcagaa gcatgttcat actgcaaatc tttaggctta ccatttacat aagaccataa
    36781 aaatttacta aaactaccat atgcttgttc aatttttaaa tacccttgag cttgattaac
    36841 aattgcttct aattttttac gatgatgaac gatatttgga aaagtcatta agcggtcgat
    36901 atcttgagcg gtcatttgtg ctaccttttc tggttcgaaa tcataaaatg cttcttcata
    36961 ggcttctttc ttttttaaaa tagttaacca agatagccca gcatgttgtg attctaatgc
    37021 taaaagttta aacaatgcct tgctatcata gagcggttgt ccccatacat gatcatgata
    37081 gtttaagtag actggatctt tagtaccaaa tgcgcattca ttcattttat tcccacctat
    37141 acattgactt attttgtcaa tcattatact ataagttaag agtttaatat aggatttggg
    37201 aagagtaagt tcaaattatt ttaaagagag catatgattt ggtgtgagta tgtaaatgat
    37261 ttttactgaa ggtagcccac agagtatctt agctgaacgt gattaatagt aggctaagac
    37321 gtgtttgagc gttaatcata atctagagtg cttgaagaga tgaagcattt caaatttcac
    37381 gatgatagta ttggtatgat tattccaatt atgttaaaag agtgaatttg atattaaaca
    37441 tccttcttga atataggtgg taccacggaa tatccgtcct atttgtatat aggatggata
    37501 tttttatttt tttaggaggt atagcaaatg gaaatgaaac caaaatatga tcctcgtgaa
    37561 gttgaagcgg gacgttatga agaatgggta aagaatggtt attttaaacc gtcagaagat
    37621 aaatcaaaag aaacatatac aattgttatc ccgccaccaa atgtaactgg taaattacat
    37681 ttaggacatg catgggatac gactttacaa gatatcatta cacgtatgaa acgtatgcaa
    37741 ggatacgata cgttatactt accaggtatg gatcatgctg gtattgcgac acaggcaaag
    37801 gtagaagcta aattaaatga acaaggaata actagatatg atcttggtcg tgaaaagttt
    37861 ttagaacagg catgggattg gaaagaagag tatgcgtcat ttattcgtgc gcaatgggct
    37921 aaattaggtc taggtttaga ttatagtaga gaacgtttta ctttagatga aggtttaagt
    37981 aaagcagtta aaaaagtttt tgttgattta tacaataaag gaattattta tcgtggcgaa
    38041 cgtattataa attgggatcc taaagcacgt acagctttat ctgatattga agtaatacat
    38101 gaagatgttc aaggtgcgtt ttatcatttt aaatatcctt acgctgatgg tgaaggtttt
    38161 attgaaattg caacaacaag accagaaacg atgttaggtg atacagcgat tgttgttaac
    38221 cctaatgacg aacgatacaa agatgtaatc ggtaaaactg ttatattacc aatcgtagga
    38281 cgcgaactgc ctattttagc agatgagtat gttgatatag acttcggttc tggtgctatg
    38341 aaagtgacac cagcacatga ccctaatgat tttgaaattg gtcaaagaca tcaattagaa
    38401 aatattatcg ttatggatga aaatggtaaa atgaacgaca aagcgggtaa atatgaaggt
    38461 atggaccgtt ttgattgtcg taaacagcta gttaaagatt taaaagaaca agatttagtt
    38521 atcaagattg aagatcatgt tcattctgta ggtcattcag aacgatctgg cgctgttgtt
    38581 gaaccatatt tatcaacaca atggtttgtg cgcatggaag acttagcgaa acgttcatta
    38641 gataaccaaa aaacagatga tcgtattgat ttttatccgc aacgtttcga acatacattt
    38701 aaccaatgga tggaaaatat tagagattgg acgatttcaa gacaattatg gtggggtcat
    38761 caaattccgg cttggtatca taaagaaaca ggcgaaatat atgttggaga agaagcgcca
    38821 actgatattg aaaattggca acaagatgaa gatgtattag atacgtggtt ctcaagtgct
    38881 ttatggcctt tctctacgtt aggttggcct gatttagaaa gtgaagactt taaacgatac
    38941 tacccaacaa atgccttagt tacaggttac gatattatct ttttctgggt cgcacgcatg
    39001 atattccaag gcttagaatt tacagatcgt cgtccattta atgatgtatt attacacggt
    39061 ttagttcgtg ctgaagacgg gcgtaagatg agtaaatcat taggtaatgg tgtggatcca
    39121 atggatgtta ttgacgaata cggtgctgat agcttgcgtt acttcttagc aacaggttca
    39181 tctccaggac atgatttaag atactcaact gaaaaagttg agtcagtgtg gaactttatc
    39241 aataaaatct ggaatggggc acgtttcagt ttaatgaata tcggtgaaga ctttaaagtt
    39301 gaagatatcg atttaagtgg taacttatca ttagcagata aatggattct aacacgttta
    39361 aatgaaacga ttgcaacagt tactgattta agtgacaaat atgaattcgg cgaagttgga
    39421 cgtgcattat ataatttcat ttgggatgat ttctgtgatt ggtacattga aatgagtaaa
    39481 attccaatga atagtaatga tgaagaacaa aaacaagtta cacgttcagt attgagttat
    39541 actttagaca atattatgag aatgctacat ccattcatgc catttgtaac agagaaaata
    39601 tggcaaagtt taccacatga aggtgacaca attgttaaag cttcatggcc agaagtgcgt
    39661 gaatcattga tttttgaaga aagtaaacaa acaatgcaac aacttgttga aatcattaaa
    39721 tctgtaagac aatcacgtgt agaagtaaat acgccattgt ctaaagaaat acctatttta
    39781 attcaagcta aagataaaga aattgaaaca actttatcac aaaacaaaga ttatttaatc
    39841 aaattctgta atcctagtac cttaaatatt agcactgacg tggaaattcc tgagaaagca
    39901 atgacatcag ttgtaattgc aggtaaagtg gtattaccat tagaagggct aattgatatg
    39961 gataaggaaa tcagccgttt ggaaaaagaa ttagctaaac ttcaaagcga attagataga
    40021 gtagataaaa agctctctaa tgaaaacttt gtaagtaaag cacctgaaaa ggttataaat
    40081 gaagaaaaac gtaaaaaaca agattatcaa gaaaaatatg atggtgtgaa ggcaagaatt
    40141 gaacaattaa aagcatagga gttagtaaca atgaattacc tagagagctt gtattggata
    40201 cacgaaagaa ctaaatttgg catcaaacca ggtgttaaac gtatggaatg gatgctagca
    40261 caatttaata atcctcaaaa taacattaag ggtattcatg taggtggcac aaatggtaaa
    40321 ggctctacag ttgcttacct tagaacagct ttagttgaaa atggttatga agtaggtaca
    40381 tttacgtcgc cgtttattga aacatttaat gaacgaatta gtctaaatgg tgtgccaata
    40441 tcaaatgacg ctattgtaga attagtatca cgtattaaac cagtaagtga aatgatggaa
    40501 cgtgaaacag atttaggtgt tgcaactgaa ttcgaaataa tcacagcgat gatgttttta
    40561 tattttggtg aaatacatcc tgttgatttt gtcattgttg aggctggatt gggtataaag
    40621 aacgattcga caaatgtctt tacaccggtt ttatcaatct taactagtat cggtctagac
    40681 catacagata ttttaggtgg tacttatcta gatattgcta gggataaagg cgcgattata
    40741 aagcctaacg ttccagtgat atatgctgtt aaaaatgaag atgcattaaa atatgttcgt
    40801 gaacgcgcaa ttgaacaaca tgcaaagcca attgaattag atagagaaat tgttgttgta
    40861 tcgcaaaatg atgaatttac ttaccgttat aaagattatg aattagaaac aatcatttta
    40921 agcatgttag gtgaacatca gaaacaaaat gctgcattag ccataacagc tcttattgaa
    40981 ttaaatgaac aaggattaat tgaattagat ttcaataaga tgatagacgg tattgaatca
    41041 gttcgttgga ctggacgtat tgagcaggtg catgacaaac ctttaatcat tttggatggc
    41101 gcacataatt cagagagtat agatgctcta attgatacaa ttaaacagta ccatgataaa
    41161 gaaaaagtag atattttgtt ctcagcaata aacggaaaac cgattaacga gatggtcaaa
    41221 catttaagtt taattgcgca tacgttttat gcaactgaat ttgattttcc gaaagcgtta
    41281 cgcaaagaag aaattgtagg tagtattgaa aatgatgaaa tacaattagt agatgactac
    41341 gttgaattta taaaaaatta tcaaggtgat acattagtaa ttaccggtag tctgtatttc
    41401 ataagtgaag ttaaatcaaa attagacttt gaagcattat aaaactaaaa ctaaaatagc
    41461 catgaagaat ctatttaatc aataggtaga gcttcatggt tattttttat gctctaaatc
    41521 gtatgtgttt ataaggttca atttcttgcc attattaatt ttgccgagca gtaatgggtt
    41581 gttaaagtat ccatcaatta tgcttagcaa tattgaaaaa tttaaatgaa aaagcggttc
    41641 aattcttgaa aaatagtgta tatttacatt ttggtaataa ctaactataa tttacataag
    41701 gaggttgtca tttggtagta ttgttatctt atagctgcag ttgtattttt agttttctat
    41761 atcaatttat atctatagaa gaaacgtcat ttgattattt acatagaaga tcgaaatgtg
    41821 attattgtaa ttcgtcactc aaatggtatg aattaatgcc gattattagt tttttattat
    41881 taaaagggcg atgtcgaaac tgtcgaaagc gtatttccct aacacatttc ttaggggaaa
    41941 cctttgcttt aatacctatc gtctttatta agtatgattt cacatacgta aatgctacgc
    42001 tatttataac tacatatgtt tttctgctta tttttactat gaccgatatc acttctttaa
    42061 tgttagattg tcgcttaatt ataatttatt gtatcgtttc tctctcgtta agtatgattt
    42121 atccagtagc ttttatcatt attagtatga ccacgcatat attctacttt ttatttcggg
    42181 catatattgg ttatggtgac gttttactaa tatctgcact ttctttgttt ttccctctcc
    42241 aattcactat ttatgtcatt ttatttacat ttgtcattgc tggtttagtt gctttaatta
    42301 ccatgatatt taagccgatt aaactattac cccttgttcc atttatattt atttcctttt
    42361 ttatcaattc acttttttat aatgatatcc atcaattttt aggaggcgta tatttttgaa
    42421 aattaaagaa atggtaactt cagaaatgcc aagagaacgt ttgttaagcc atggtgcaaa
    42481 aagtctttcg aatacagaat tattagctat attaattaac accggaagaa aaggattctc
    42541 gagcatagac attagtaatg aactgcttaa atctgcttcg aatctgaatg aattgaaaaa
    42601 atcttcaatt aacgatttga taaaagttaa agggattgga ttacaaaaag caattacttt
    42661 aaaagcagca tttgagttag gggaaaggat ggggagaaga gctgaaaata atcgtataaa
    42721 aataacgcaa ccaagtgatg ttgctgatta tatgattcca acaatgaaag atttaacaca
    42781 agaacatttt gtcattttat tgttaaattc aaaaaatgta gtgattaaag aaacctgtgt
    42841 ttttaaaggt acattaaata gttcgattgt acatccacgt gaaattttta gtattgcggt
    42901 gagagaaaat gccaatgcaa tcatcgcagt tcataatcat ccatccggtg atgtattaac
    42961 catagtataa taaataatag tagttaaagt agtttaagag gagatattaa agggatattt
    43021 tactttaaat aaaaattaac aaggtttata atttgtagta gttaaagtat ttaaagaggt
    43081 gggaacatgt gaaggttcaa aggatagaag tggagaataa gccgtatcca ttgtatttat
    43141 tactagataa agaataccag ctaatagaac cagtaatgaa atttattaaa tacttagata
    43201 atactggtaa gtctcctaat accattaagg catactgcta tcatttaaag ttgctgtacg
    43261 agttcatgga acagagaggt gttattctta atgatattaa ctttgagttg ttagcagact
    43321 tcgtaggttg gttgagatat ccttcagcat caaatgtaat tgatcttcag tcaaaaaaag
    43381 ccataagaga agaaacgaca gtgaatacaa ttttaaatgt agttatgagt tttcttgatt
    43441 atttaagtag attaggagaa tttaaatcaa ttgatgtatt taaacaagca aagggaagaa
    43501 atttcaaagg atttttacat catgttaata agggtagata ccaaaagaat gtcttaaagt
    43561 taagggttaa aaagaaacag ataagaacat tgagatcaaa ggaagttaag caaattattg
    43621 atgcttgtca tacgaaaaga gataaattaa ttttaatgct tatgtatgag ggtggtttaa
    43681 gaatcggtga agtgttatcg cttaggcttg aagatattgt cacttgggac aatcaaatcc
    43741 atttaacacc tagagatgtt aatgttaatg aagcttatat taaattaagg aaggaaagaa
    43801 caatacatgt gagtaaagaa cttatgtcac tttatacaga ttacttgata tatgagtata
    43861 gtgaggaatt ggagcatgat tatgttttta tttccttaaa agaaggctat tttgggaaac
    43921 cactaaagta ccaaagtgtt cttgatctag ttagaagaat agttaaaagg actggaatag
    43981 aatttacatc acatatgctt cgccacactc acgcaacgca gctaattagg gaaggatggg
    44041 atgttgcgtt cgttcaaaag agattaggtc acgcacatgt tcagacaacg ttaaatacct
    44101 atgttcatct ttcagatcag gatatgaaaa atgagtttaa taaatacctc gagagaaagg
    44161 agcataagaa atgaatgctt ctagtaaaag gaaaattatt agtcagagtg agattagcaa
    44221 aaaaatagct gtaatgaatg aagaaatgca ggggttttgg gctaataata gttgggatat
    44281 aagaaaatgt ccacatcctt ctgccataga attaagtaag aatcctgctt taaggaatcg
    44341 ttgggttcgt tttgaacgtg ttaaaaatct gtggttaaga acagaattga aatattttta
    44401 tttttaccat ttaaacaatg gaatatggaa tgcaaaaact gtctggatta gaaaaggaac
    44461 agtaattaat aaaatgttag atttcttaga tttaaagtat cctagcatta cttcaattac
    44521 tgaagttcct attgaaaaag caatgacgga gtatagaact tatttgacaa aacggggtgt
    44581 tagaattacc actactaatt ataagattac tgctaatcaa gaaaaaacac ctgtaaaagc
    44641 taattcctac tatgttacta atctaaaaca atttatggag ttttatgaga acttttattt
    44701 tgatggagag gagtgggata aagacgtttg ggatagacgt aacttacctt tgccagatga
    44761 taaggttaac ccaacacaat atgaatatac aattaacttt aaagggtttc ggaatacata
    44821 ttttaaacaa cttgtaaaaa gatattgtaa gttgagattg aacgtggata gcttttccta
    44881 tgtaagtgat attgcccaaa gacttaaaga gttctttaat tttctggaca tgaaatttaa
    44941 acaagttcag agagtacacc aattaacgag agtggaaatt gaagcatatt taagtgaact
    45001 aaacatgatg ggaataaaac ctagtacaat aactgggagg atctctatat tggaaggact
    45061 atttagtacc cttcttaggc tagaatggga tgatgttcct tccaaaatat taatttattc
    45121 tgaggactat ccgaaaatac caagagcaaa accacgcttt atagatgaat tcgtcctaga
    45181 gcaattgaac agtcatcttg ataaattacc cgaatatata gctacgatga ctatgattgt
    45241 tcaagaatgt ggaatgagga taagtgaatt gtgcaccttg aaaaaaggct gtctattaga
    45301 ggacaaagat ggagatttct ttttaaagta ttatcaatgg aaaatgaaaa aggagcatat
    45361 agttccaata tctaaagagg tagctttact tattaaagtt cgggaagata aagtttcaga
    45421 ggaatttcca gatagtgaat acctctttcc aagaaaagat ggatcgccat taaaacaaga
    45481 aacatttaga ggtgagttaa ataaattagc ttatgagcaa aatatagtgg ataaatcagg
    45541 tgagatttat agattccatg cccatgcctt tcgccataca gtaggaacaa gaatgattaa
    45601 caacgggatg ccccagcata ttgtgcagaa atttttgggg catgaaagcc cagaaatgac
    45661 aagcagatac gctcatatct ttgatgaaac tctaaaaaat gaatttacta aatttcagga
    45721 aaaactggtt accaataatg gagatgtgct tgatctagat gaagataatg aagtcgatga
    45781 tgtagagctt caatggttca agaaaaatat aaatgcacaa gtgcttccaa atggttattg
    45841 tagattgcca gtagtagcag gtggttgtcc acatgcgaat gcatgcttag attgcactca
    45901 cttctgtacc agtaagcaat tcttaccaca gcacgaagaa cagttagagc gtacagaaga
    45961 gttattagcc atagctaagg ataaacaatg gcaaagacaa gtagagacta atagccgtgt
    46021 taaagagcgt ttagaacaaa tcattggaag tttgacgggg taattatcaa tggataaaca
    46081 agttagaaat acaacagaaa ttgtacgttt ggcgaagcag aaatcaaaaa agacaaggga
    46141 aaaagtagac aaagcgattt ctaaattttc gattgaaggt aaagttatta attttaattc
    46201 aatagcaaag gaagctaatg tttctaaatc atggctttat aaggaacacg atattaggca
    46261 aagaatcgaa tcccttcgtg agcgtcaaat aacagcaaat gtagtctcaa aacccaagaa
    46321 aagttctcgt tcggaggaaa tccttattaa aaccttaaaa agaagagtaa tggaattaga
    46381 aaaagaaaat aaaaaattac agaaccaaat tcaaaaatta tatggagatc tgtataataa
    46441 agaataatta ttaatctgta gacaaattgt gaaaggatgt acttaaacgc taacggtcag
    46501 ctttattgaa cagtaattta agtatatgtc caatctaggg taagtaaatt gagtatcaat
    46561 ataaacttta tatgaacata atcaacgagg tgaaatcatg agcaatttga ttaacggaaa
    46621 aataccaaat caagcgattc aaacattaaa aatcgtaaaa gatttatttg gaagttcaat
    46681 agttggagta tatctatttg gttcagcagt aaatggtggt ttacgcatta acagcgatgt
    46741 agatgttcta gtcgtcgtga atcatagttt acctcaatta actcgaaaaa aactaacaga
    46801 aagactaatg actatatcag gaaagattgg aaatacggat tctgttagac cacttgaagt
    46861 tacggttata aataggagtg aagttgtccc ttggcaatat cctccaaaaa gagaatttat
    46921 atacggtgag tggctcaggg gtgaatttga gaatggacaa attcaggaac caagctatga
    46981 tcctgatttg gctattgttt tagcacaagc aagaaagaat agtatttctc tatttggtcc
    47041 tgattcttca agtatacttg tctccgtacc tttgacagat attcgaagag caattaagga
    47101 ttctttgcca gaactaattg aggggataaa aggtgatgag cgtaatgtaa ttttaaccct
    47161 agctcgaatg tggcaaacag tgactactgg tgaaattacc tcgaaagatg tcgctgcaga
    47221 atgggctata cctcttttac ctaaagagca tgtaacttta ctggatatag ctagaaaagg
    47281 ctatcgggga gagtgtgatg ataagtggga aggactatat tcaaaggtga aagcactcgt
    47341 taagtatatg aaaaattcta tagaaacttc tctcaattag gctaatttta ttgcaataac
    47401 aggtgcttac ttttaaaact actgatttat tgataaatat tgaacaattt ttgggaagaa
    47461 taaagcgtcc tcttgtgaaa ttagagaacg ctttattact ttaatttagt gaaacaattt
    47521 gtaactattg aaaatagaaa gaaattgttc cttcgatagt ttattaatat tagtgacatt
    47581 tgcatgcttc aaagcctgtc ggaattggtt tttagtgaaa agaacacgat attcacggtt
    47641 tacccactta taaacaaaag atcgatactt tttgtagtcc ttctttgaaa tcaatggttg
    47701 atgtcgctca agaacaatca atacagagtc tacacttggc ttaggatgaa aatatagtgg
    47761 tggtactttt ttgagcattt ttatatccat ctccaccatt aatagtaaac ccaaagctcg
    47821 ttgcagattt tgcaatcttt tcgcaaatcc cttctcaacg ataagatagc tatatttagc
    47881 ctgactttca aaggtaattc ttttgacaat atccgtactg atgttataag gaatattacc
    47941 atatatctta tagtttatat gttttgggaa ggaaaatttt agaatatccg tttgaatcac
    48001 ttttatattc tcagaggggt ttaccgcttc tttagtcact tgacataagc ctccatcaat
    48061 ttctatagca gtaactgatc gactcatttt gactagctct ttggtaaaat gtccttttcc
    48121 tgatccgatt tctattacgt tgtcttgttt actgatattc gtgtgattca atatttcttt
    48181 tacatgcttt ttagaagtaa taaaattttg cgtgtcttta gggtttttct ggttcattat
    48241 aaccttctcc ttttttttca ttatgaatga gataaagtaa tttctactac tgcgatactg
    48301 gtgcacataa ttgaaacctc cttatgtaac tgaatatgat tgtatcatct tttcatttta
    48361 gaataaacct ttatatgtaa ttttgcactt gacacttcag atggacgttt tcttcaaaat
    48421 aatatgtttt gaaacttgat aagagaagcc actgtcttta ctaaaaagta aaggctgcga
    48481 taaaggacag tgactttaat aaagttgcac tgttgtattg tctttggata aaattgtcta
    48541 aagggaagtt ttatccccaa cgaaaaaaca tctaaagtgg taagtaatga aagaatgtcg
    48601 ataaagtagg aatgggggat ctttttgaat acaatagaat cacagtttga taaggttgca
    48661 gaagattacg atttcgtgaa tgagcttttg aatgattatt cattctttgt gtctaatatg
    48721 tctccaaaga aaggcagagc attagatatc ggatgtggct cgggtttgtt agtggagaaa
    48781 ttagcaagtt attatgatga agtggtaggg attgatattt ctaatcaaat gctcgatctt
    48841 gccaaatcta aacgtcaact aacaaatacg gtctatctga atatgaatgc agaacaactt
    48901 aattttaatg agaagtttga ttttattgta agccgaacaa cctttcatca tttggatgat
    48961 atagccagcg taatacagca aatgaaggaa ctgttgaatg aggaaggaag aatagttatt
    49021 cttgataatg tatctgaagt cgagacaccg cctacctatg tttataaatt aggggcaatc
    49081 caagagtttt taccgcattg tttcaaattt ggaataaaaa atgcgattag aatttataat
    49141 cacaacacat ctaaatcatg gcttgagcat ttagcttcag ataagtacct atctgaacaa
    49201 aattattacg atttatatga aaagttgttg cctggatgcc aattccataa aatgggttgg
    49261 gcaatggggg ttgtctggac aaaataactt aaagctgtgg ctttgaaaag ttgaatttgt
    49321 gattgttttc agagctatcg ggtgctttag tataaataac aatgaataaa aaatcagcct
    49381 gtatcttatg ttactattaa gtaatttaag atacaggttt tactattttt gaaataagta
    49441 ccttccactt caaatacatg tattcaaagt gaaagtattg atttaaatga ttcttttgta
    49501 atttactctt gataagatgt aacgccctca caagaagata tcataacaac aatgaggttg
    49561 aaggagtgtg gtttgatttt agggatagat ttattggatc atattataat cggtgataat
    49621 agatttacca gtcttgtaga agcgggttac tttgatgaaa atgattgaag ttgatagaat
    49681 taatgacgta tcttgtgtat aatacctacg aagtactttc attggaggaa aaatagtgac
    49741 tctatttatt attatcgggg ttctcgtgcc aatggtttat accatgcagt taaatattaa
    49801 aaatgaacct gtaacaaagc gcaatctatt aataacatta gctttatcta cgttaggtat
    49861 tttagtaacg gcgttagcag gtgtgatcgt tacgaaacaa gcttttcctt tattaagtgt
    49921 agcaatcggc tcaattttta ctggaatcgt ttggggcctt ttactaagtg gtagctacgc
    49981 gctgatacga tttttatcta acgcatttgg gcgtaagtaa tagtaatctg ttcatcaagt
    50041 agtatccgtg cttgaaacca aattaaaact cctaatgtgg aactagttaa aaaattctaa
    50101 actagtacat taggagtttt gttatgcaga ataaatttaa ttgttaaatt gaaagtgcgg
    50161 taaaaaccca ctatttattt gaaaaaaatc gagcaaccaa attaaacctt gatatcctaa
    50221 gtaaatacat aataaaacaa gtccgacata aattaaaaat cgcaaaatag aaagtccaac
    50281 tctaaaaagg aggatgacta atagtgctat taaaataatt gttagtatac tcaatgctac
    50341 aaacctcctc atacgctttt aaatcataac aaaattataa gctattttaa atgaacgtgc
    50401 atcagtccta agatatatca tgattaaggc tgaagactga ggaaaatata cataataaaa
    50461 tatataatta gatgaagaca ttggaggcga actatgagat tgatatttag tatgattaaa
    50521 aacattatag cagtaatagc aattgtgata attgtttata tcgccttgaa atacgcacct
    50581 tttttaaaag aacaagattg gaatcctgta aatcacgata atgatcaaat gaatcaagtt
    50641 acgcaaccca ctaatgatgc ccaacatgtt tatgtaagtg gtgagaaata ttcattaaaa
    50701 gaaaatgatt taataaagaa tgtaccatta agccaaatta aaaatgtatt taaaatgata
    50761 gataaacaag agtttatggc tgtgtctgga atgaatcgca tggcttataa tgatcaatat
    50821 attataggtc aaagaggaga cgaatttatt ctttataaat ttggagatga gtcaatgcgt
    50881 gtttacaata ctgaatttga aatgcaacaa gacttaaatg aattagggca aaatttacaa
    50941 ctaaaacccg aaaatgctta tcaataggaa attattgcat aagaaatata ttttagttat
    51001 cctgtcacta gaataaattt aaaaggttgg tgtagttcaa atggcagaac aatcaaaaca
    51061 gaaacaagct aatgaacaac aaaaggccca gaacttattc gcacgttgga gacaacttca
    51121 gaattcgaac agtgaatcct cgaacgatac aaacaaataa ttttaaaatt taaatcgatt
    51181 atttaaacta ctagtgactg gaatgtttgc tagtagtttt ttgtttttaa aatgccacaa
    51241 attttttacg gagttgttca ttttcaaagt aattcgtagt tagtgcttta tttcataatg
    51301 ggagtaatat aaaatagaaa aggatataca atattttgac ataatagagg tgttctgggt
    51361 gcttaagttt tttaaaaata acaaattaat tgttgtttta tgtgcaatta tcgtttttat
    51421 tgcattaatt gggctgtcca tacgttcaca atctcaatca cctcctgaac aatatatagg
    51481 tgattctgtg tcttttggac aacgagttgt gagttatcca gttaattttg ttgctggtac
    51541 gattggggac ttttttaaaa aaggagattc taaagaatct aaaaataaga ttagccagtt
    51601 agaatctaag aaccaacaat tagaagcgga aaatgaaaaa ttaaaaaaag agcttgattt
    51661 aaaagatatt tcaaaatttg atcctatttc tactacggtt ttagcaagaa atccggatca
    51721 gtggatgaat acaattgtaa ttgataaggg atctaaatca ggtataactt caaatatggc
    51781 tgtgatgaca tcacaaggtt ttgttggaag agttactaaa gttaataaat tttcttcaca
    51841 agttgattta atctcaacta atacacgtgc gggtaaatta tctgtaaata tacaacacgg
    51901 ttctaaaaat atatttggtt taattgatcg ttatgatgaa aagaactcag aacttgtaat
    51961 tagtgacatt aataatagag ataatatctc aaaaggtgat aaagtcgtta caagtggatt
    52021 agctgatcaa ctaccaagta atttatatat aggagaagtg actaaggttc aaaatgatca
    52081 atacggctta gctaaagaag ttagggttaa gactggtgca gacttaacag atttgagtca
    52141 tgtttatgtt gcaaaaagag atcctaaaac aattcctgat gatgaaagca gggataaata
    52201 atgcgtacac tgtattattt tttgataggt attttactat tttatataga tactgcaatt
    52261 gggcttctta ttccaatgca tataggtaag tttgaacttg tatttgtacc acaccttaca
    52321 tttatgtata ttttaatgat ggtagtgtat cgtggctttg gcgtatcatt attgctcagc
    52381 atatttttag gcgtaatgac tgatgtatac tttggtagta tttatggagt gtacttattt
    52441 ggctatatat tgtttttagc acttatagat cgattcttta aaatttttta caaagatcat
    52501 tcgatgttat tcattattat attagccagc accttattat tagaagtcta tgtggtatta
    52561 atatacggta tgttaggatt cattcaattt gatattattc attttgtagt ctttagatta
    52621 ttgccaacat taattatgaa ttttgtactg ttgattatgc tttatccgtt gattataaag
    52681 ttccttaaaa aaacaaacaa tgacattgac atgaaacgtc gtcaatggta agatgcaata
    52741 gttgagtagt tataagtagc tacatacaac cgctcaaata taggttcaag aacattttta
    52801 atgaagaaag cgattgtcaa tcaaggcgtt gaaggaagaa acgagaagag tttatgttta
    52861 taaatgactc gagttgcgac cgaaacaacg tagagtgcaa acgcttgact caataacgaa
    52921 atgtcaccta tgtatggcgt gacttattat acaggaggtg caaagtatgt ttgctattat
    52981 tgaaacaggt ggaaaacaaa tcaaagtaga agaaggtcaa gaaatcttcg ttgaaaaatt
    53041 agacgtaaac gaaggagata cttttacatt tgataaagta ttatttgtag gtggagattc
    53101 agttaaagtt ggagcgccaa cagttgaagg tgcaacagtt actgctactg ttaataaaca
    53161 aggtcgcggt aaaaaaatca ctgtattcac atacaaacgt cgtaaaaatt caaaacgtaa
    53221 aaaaggccat cgtcaaccat acactaaatt aacaatcgat aaaatcaacg cgtaattatt
    53281 atgattactg ttgatattac agttaatgat gaaggcaaag taacagacgt tattatggat
    53341 ggccatgctg accatggtga atatggtcat gatatcgttt gtgctggagc ttcagctgta
    53401 ttgtttggta gtgttaatgc gattatagga ttgacatctg agagaccaga tatcaattat
    53461 gacgacaatg gtggtcattt tcatataaga agcgttgata caaataacga tgaagcgcaa
    53521 ctaattcttc aaacaatgct tgtgtcttta caaactattg aagaagaata taatgagaat
    53581 attagattaa attataagtg aggtgcattc cgatgttaaa attaaactta caattcttcg
    53641 catctaaaaa aggggtaagt tctacaaaaa acggacgtga ctctgaatca aaacgcttag
    53701 gtgctaaacg tgctgacggt caattcgtaa caggtggttc aattttatat cgccaacgtg
    53761 gtactaaaat ttaccctggt gaaaatgtag gtcgtggtgg cgatgataca ttattcgcta
    53821 aaatcgacgg cgttgttaaa ttcgaacgta aaggtcgcga caaaaaacaa gtttctgtat
    53881 atgcagtagc tgaataattt tgtctagtta acaccagaag tgaatcttct ggtgtttttt
    53941 actttttata aaaggttttt cattattatt ttaattatgt tattaaaaaa tggggatttt
    54001 agacgttata ctaaatgtac aactgcataa gagcccctaa tcgctaaact ataaggggac
    54061 aaaagaatac agttgcagta taaaaagcaa aaaaagtatc atatttggta ttcggaaata
    54121 tcagcaattt gagtaaagta aatttaaaag caactgcata agagccccta attatttaca
    54181 atatataagg ggctctaata tgctataatt attgggaaaa tgaaaattat atgtaaaaga
    54241 ggtgagatat atgtttgtcg atcaagtcaa aatatctctt aaagccggtg atggtggtaa
    54301 tggtattacc gcatatagaa gagaaaaata tgtaccattt ggtggaccag ctggcggtga
    54361 cggtggtaaa ggtgcttcag tcgtatttga agtggatgaa ggtttaagaa cgttattaga
    54421 ttttagatat caacgtcatt ttaaagcaag caaaggtgaa aatggccaaa gtagtaatat
    54481 gcatggtaaa aatgcggaag atttagtatt aaaagttcca cctggtacaa ttattaaaaa
    54541 tgttgaaaca gacgaagtgt tagcagatct tgttgaagat ggtcaaagag ctgtagtagc
    54601 gaagggcggt cgaggtggcc gaggtaattc acgttttgca acacctagaa accctgcacc
    54661 tgacttcagt gaaaaaggtg aaccaggtga ggaattagat gtatctttag aattgaaatt
    54721 attagctgat gtaggattag taggtttccc tagtgtgggt aaatcgactt tattatctat
    54781 cgtttcaaaa gctaagccta aaattggggc atatcatttt acaacgatta aaccaaatct
    54841 aggtgttgtt tcaacgcctg atcaacgtag ttttgttatg gcagatttac caggtttaat
    54901 tgaaggtgca tctgatggcg ttggattagg acatcaattt ttaagacatg tagagagaac
    54961 aaaagttatt gttcacatga ttgatatgag cggttctgaa ggtagagaac ctattgaaga
    55021 ttataaagtc attaatcaag aattagctgc gtacgagcaa cgtttagaag atagacctca
    55081 aatcgtagta gctaacaaga tggatttacc tgaatcacaa gataatttaa acttgtttaa
    55141 agaagaaatt ggcgaagatg tgccagttat tccagtttca acaataacgc gtgataatat
    55201 tgatcaatta ttatatgcaa tagcagataa attagaagaa tataaagatg ttgacttcac
    55261 agttgaagaa gaggagtcag ttggcattaa ccgagtatta tataaacata caccgtcaca
    55321 agataaattt acaatttcaa gagatgatga tggtgcttat gtggtaagtg gtaatgctat
    55381 tgaaagaatg tttaaaatga ctgactttaa cagtgatcca gcagtacgtc gatttgctcg
    55441 tcaaatgcgt tcgatgggta ttgatgatgc acttagagaa cgtggttgta aaaatggtga
    55501 tatcgttaga attcttggcg gagaatttga attcgttgaa taggagcgta acatgatgga
    55561 caataaagat tataaaaagt tttatttaat tagagaagat gtcttgcctg aatccgtggt
    55621 taaaacattg aagattaaag atgccttaaa aagtgatccg acattgtcca tttatgatgc
    55681 cgttaaacag tttgatctat ctagaagtgc tttttataaa tatagagaaa cgatatttcc
    55741 agtagacgat aaaatgcttg accatcgaga atttacatta attttatatg taactgatat
    55801 tgtgggtatg ttggcacgtg tactagatgt tatatcaaag ttagaactat ctgtattaac
    55861 gattcatcaa agtattccaa tggaagaaaa agcaacaata acattatcac tgaatgctaa
    55921 atctaaagaa acttcagtag aagatgttat tggtgctttg agaaatttag attatgtatc
    55981 aaaagtagaa ttaattagta tgagtatgta aggatgtgcc tataatgtac gcgtatgtca
    56041 aaggtaagtt aacacattta tatcctacac acgtagttgt tgaaactgct ggtgttggtt
    56101 atgaaattca aacaccaaat tcttatcgtt ttcaaaagca tctagatcat gaagttttaa
    56161 ttcgtacatc tttaattgtt cgtgaagatg cacaattatt gtatggattt agtagtgaag
    56221 aagagaaaga tatgttcttg agtttaatta aagttactgg tattggtccg aaatcagctt
    56281 tagctatttt agcgacaagt acgcctaatg aagtaaaacg tgccattgaa aatgaaaatg
    56341 atacgtattt aactaaattc ccaggaattg gtaagaaaac ggcaagacag attgtcttag
    56401 atttaaaagg taaagtgaaa atcactgaag aagatagcga ttcattatta caagtagacg
    56461 ctacttcgac ggtgcaagat caattcgtgc aagaagcaat gttagcgtta gaagcattag
    56521 gttattctaa acgagagctt gcaaaagttg agaaaacgtt aaataaaaat aaatatgact
    56581 cagttgatga agctgttaag gcaggtcttc aattagttgt atcttaattt taaatagatt
    56641 aataggggaa gtgttgtcat gaatgagcgt atggttgatc aatcaatgca tagtgaagaa
    56701 actgatttcg aattgtcgct tagacctacg agattacgac aatatattgg tcaaaattca
    56761 ataaaaagta atttagaagt atttattaaa gcggctaaac ttcgtcatga accattagat
    56821 catgtattgc tttttggccc ccctggatta ggtaagacaa cattatctaa tatcattgcc
    56881 aatgaaatgg aagttaatat acgtacagta tcagggcctt cattagaaag acctggtgat
    56941 ttggctgcaa ttttatcagg acttcaacct ggagatgtat tgtttattga tgaaatacac
    57001 agactgagta gtgttgttga agaagtgtta taccctgcaa tggaagattt ctttttagat
    57061 attatcattg gtaaaggcga tgaggctaga agtatccgta tcgacttacc tccattcact
    57121 ttggtaggtg caacaacgcg agctggcagc ttaacaggtc cactaaggga tcgatttggt
    57181 gtgcacttaa gattagaata ttataatgaa tcagatttaa aagaaatcat tattagaaca
    57241 gctgaggttt taggcacagg tattgatgaa gaaagtgcca ttgaacttgc taaacgttct
    57301 agagggactc caagagtagc aaatcgacta ttgaagcggg taagagactt ccagcaagtg
    57361 aatgaagatg aacaaatata cattgaaaca acgaagcacg cattaggttt acttcaagtt
    57421 gatcaacacg gactagatta cattgatcat aaaatgatga actgtattat taagcagtat
    57481 aatggtggac ctgttggttt agatacgatt gccgtaacaa ttggtgaaga acgtattaca
    57541 attgaggacg tttatgagcc atttcttatt cagaaaggct ttttagaacg tacgccacgt
    57601 ggcagaaaag caacaccatt agcttatgaa cattttgcaa agtcgaatga ggagagagga
    57661 taacgtgaat attgaagaat ttgactatga cttaccagaa tcattaattg ctcaaacgcc
    57721 tttaaaagat cgtgatcata gtcgtttatt agtcatggat agagaaactg gtgaaatgaa
    57781 acatttacat ttcaaagata tcattgagta ttttagacct ggtgatacat tagtgcttaa
    57841 cgatacgcga gtaatgccag ctagactttt tggtttaaaa gaagaaactg gtgcaaaagt
    57901 tgaaatgtta atgttaactc aaattgaagg taatgattgg gaagtcttac tgaaaccagc
    57961 taagcgtatt aaagttggta ataaattgaa ttttggtaat ggcaaaatta tagctgagtg
    58021 cataaaagaa atggatcaag gtggacgcat catgcgttta cattatgaag gtattttaca
    58081 agaaagatta gatgaattag gggaaatgcc actgccacca tacatcaaag aacgtttaga
    58141 tgatccagat cgttatcaaa cagtttacgc taaagaaagt ggttcagcgg cagcaccaac
    58201 agcaggatta cattttactg atgagttatt aactgaaatt aaaaataaag gcgttaatat
    58261 cgcatttgtt acattacatg ttgggttagg tacgtttaga ccggtgagcg tcgatgatgt
    58321 gaatgaccac gaaatgcata gtgaatatta tcaaatgaca caagaaacag ctgatttatt
    58381 aaatgatact aagtccaaag gacatcgcat tatatcagtt ggtacaactt caacacgtac
    58441 acttgaaaca attcgacgcg atcatgataa atttgttgaa acgagtggct ggactaatat
    58501 atttatttat ccaggatttg attttaaagc aattgatggc cagattacta attttcattt
    58561 accaaaatca acattagtta tgctagtatc agcgtttagt actcgtgaaa atgttctgaa
    58621 tgcttataaa acagcagtaa atttagaata tagattcttt agttttggcg atgcaatgtt
    58681 aattatataa aaagaatgtg aggattttga atatgcctgc agtaacatac gaacacatta
    58741 aaacttgtaa acaatcaggt gcgcgtttag gtatcgtgca cacaccacac ggttcatttg
    58801 aaacacctat gtttatgcca gttggtacta aagcaaccgt taaaacaatg agtccagaag
    58861 agttaagaca aattgaagca aaaatcattt tgggcaacac atatcatttg tggttacaac
    58921 ccggaaatga tattatcaaa cacgctgggg gattacataa attcatgaat tgggatggtc
    58981 cgattcttac agattcaggc ggtttccaag tgtttagttt aagtaattta cgtaaaatta
    59041 cagaagaagg cgtggaattt agacatcata ctaatgggtc taaattattt ttgagtcctg
    59101 agaaatcaat gcaaattcaa aatgatttag gatctgatat tatgatggca tttgatgaat
    59161 gtccaccgat gcctgctgaa tatgattatg taaaaaaatc tattgaacgt acaacacgtt
    59221 gggcgaaaag atgtctagat gcacaccaaa gacctgaaga tcaagcattg ttcggcatta
    59281 tacaaggtgg cgaatatgaa gatttaagag aacaaagtgc aaaggattta gtagaattag
    59341 attttcctgg ttatgcaatc ggcggtttgt cagttggtga acctaaaccg gttatgtata
    59401 aaatggttga acatacagag cagtttatgc ctaaagataa accaagatat ttaatgggtg
    59461 taggatctcc agatgcgtta atcgaatgta gtattcgcgg catggatatg tttgattgtg
    59521 tcttaccgac acgtattgcc agaaatggta cttgtatgac atcgcaaggt cgtttagtta
    59581 ttaaaaatgc aaaatttgca gatgatttaa gaccgttaga tgagaattgt gactgttata
    59641 catgtcaaaa ctattcaaga gcgtatatac gtcatttaat caaggcagag gaaacttttg
    59701 gtattcgtct tactactatt cataatttac attttctgct aaaattaatg gaagatataa
    59761 gacaagccat tcgagaagat cgtcttttag atttcaaaga agaattcttc gagcaatatg
    59821 gattaaatgt tgagaaccca aaaaactttt aagcaagagg agcgtataaa atgcaatttt
    59881 cattactaat atatatagtc gtaatttttg cggttatgta tttcttgatg atcagaccac
    59941 aacaaaaacg tgcgaaacag catcgtgagt tgattaataa cattcaatct ggtcaaagaa
    60001 ttacaactat tggtggtatt aaaggtactg ttaaagcagt agatgaaaca actgttgtta
    60061 ttacagttaa tggtcatggt actgaattaa ctttcgaaaa acctgctatt aaacaagttg
    60121 acccttcata acgagaagtg gtattaaaaa ggatgaaacg aatagcgttt catccttttt
    60181 aagttataag tagtatgtag aatagcttat ttttattcca aaaaaagaaa ttgtgataca
    60241 taataattgt taaatttaaa ttaaatatat ctatgactat ttttactccc tgctctagta
    60301 tgttaatatg tataaggcta ataaattttg taagaaagat ttaacttgcg ttataaaata
    60361 gtattcaagt attctaaata catacgtaaa taatgaggtg ttcatgtgaa gaaaagtagt
    60421 agaataattg cgttcttgct tttagtcgta ttgttgtttg ccggaatggc tgcaacttat
    60481 aaaagtgtta taaagaatgt caatttagga cttgatttgc aaggtggatt tgaggtgctt
    60541 tatcaagtcg atcctttaaa taaaggcgac aaaatagata aaaaagcctt acaatcaaca
    60601 gcgcaaacat tagaaaatcg tgttaacgtt ttaggtgttt cggaacctaa aattcaagtt
    60661 gaagaaccta atagaattag agttcaactt gctggtgtaa cagaccagaa tgaagcacgt
    60721 aaaattttat cttctcaagc taatttaaca attcgcgatg cagaagataa agtaaaatta
    60781 agcggttctg atattaaaca gggatctgcc aaacaagaat ttaaacagga aacaaaccag
    60841 cctacagtta cttttaaagt aaaagacaaa aacaaattta aaaaagtaac ggaagaaatc
    60901 tctaagaaac gtgataatgt catggttgtt tggttagatt tcaaaaaagg tgacagctat
    60961 aaaaaagaag cacaaaagaa aaaccctaaa tttatttctg cagcaagtgt tgatcaacca
    61021 atcaattctg atagcgtaga aatctcgggt ggatttaaag gacaagaagg cgttaaaaaa
    61081 gcaaaacaaa tcgccgaatt gttaaatgca ggttctttac cagttgactt gaaagaaatt
    61141 tattcaaact cagtaggtgc ccaatttggt caagatgcat tagataaaac tgtgtttgca
    61201 tcgtttattg gtgtagcatt aatttattta ttcatgcttg gattctaccg attacctggt
    61261 ttagtagcga ttattgcatt gacaacttat atctatctaa cgttagtagc atttaatttc
    61321 atttccgggg ttctaacttt accaggatta gcggcgttgg tattaggtgt aggtatggct
    61381 gtagatgcca atattatcat gtatgagcgt attaaggatg aacttcgaat aggtagaacg
    61441 ataaagcaag ccttttctaa agcaaacaaa agttcattcc taacaatttt tgattctaac
    61501 ttaacaacag ttatcgccgc agcagtatta ttcttcttcg gtgaaagttc agttaaaggt
    61561 ttcgcgacaa tgttattatt aggtattcta atgatctttg ttacagccgt gttcttatca
    61621 agattcttat tatcattact tgtttcatca aatatattca aaaatcaatt ttggttattt
    61681 ggtgttaaaa agaataaacg acatgatatt aatgaaggtg tagatgttca tgaccttaaa
    61741 acttcattcg agaaatggaa ttttgttaaa ttagctaagc cattaattgg agtaagtatt
    61801 ttaattgtag ttgtcggttt agttattctt tatatcttca agttaaactt aggaattgat
    61861 ttctcaagtg gtacacgtgt agatttccaa tctaaacaag caattactca acaaaaggtt
    61921 gagcaagttg taaaagatag tggacttaaa gcggatcaaa ttcaaatcaa tggtaaagat
    61981 aataaagtag caactgttca atttaaagac gatttaacgc gtgctcaaga taataaattg
    62041 agtgataata ttaaatcgaa attcggtgac acacctcaaa ttaatactgt atcaccaatt
    62101 attggacagg aattagcaaa aaatgcaatg cttgcattaa tctatgcatc gataggtatc
    62161 atcatctatg tatcattacg atttgaatgg cgcatgggtc tttcatctgt attggcatta
    62221 ttacatgatg tattcattat agtagcgatt ttcagtttat ttagaattga agtagattta
    62281 acatttatcg ccgctgtatt aacaattgtc ggttattcaa ttaatgatac aatcgtaacg
    62341 tttgaccgtg tacgtgaaaa cttacaaaag gttaaagtga ttacgacaac agaacaaatt
    62401 gatgatatcg ttaatagatc aattagacag acaatgacac gttcaattaa tacagtatta
    62461 acagttattg tagtagtagt tgctatacta ttcttcggtg ctcctacgat attcaacttt
    62521 actttagcat tatttatcgg attgatttct ggtgtattct cttcaatctt cattgccgtt
    62581 ccgctatggg gaataatgaa aaaacgtcag ttgaaaaaat cgccgaaaca caaattagtt
    62641 gtatataaag aaaagaaatc gaacgatgaa aagattttag tttaaaatga attaagcggt
    62701 atgtgaaaca ataaagagtt cacataccgc tttttacttt atttaaattt aacaaaatat
    62761 atataaataa gttcccgcat tcatttttaa aaaatggtat aattaaagtc ttgattattt
    62821 agataagtgc tttttattta aagtaatttt agatataatg tcttttggaa atgaggcgta
    62881 aatatatatg attaaaccga agtataagtg gaaattaact aaaccagctg aatacataag
    62941 tgatgaatta acatcaaaat taaagttaac gccaatcgta aaaaaaatat tagaaagtaa
    63001 atcgattatt gatgaacaag caattgaatc catcatttca gacacagatg tcaatcatga
    63061 tgcattgcaa ttgagcgata tgactaaggc tattgaaaga attaaaagag cgatagcgaa
    63121 tgatgagaaa atcctagttt atggtgatta cgatgccgac ggtgttacct caactacaat
    63181 tttagtgaca acattacaac ttttaggtgc acaagtagga tggcatattc ctaaccgctt
    63241 taccgaagga tatggaccaa acgaactagc atttagaaat gctcatgatg aaggcataac
    63301 attaatcata actgttgata atggcataca aggtcataat gaaattaaaa tggttcaaga
    63361 tttaggagtt gatgtcattg taactgatca tcatgaaatt ggtagtacat taccagaagc
    63421 atatgcaatc gtacatccaa tgcatccatc gtttaattat ccgttccaac aattgtgtgg
    63481 tgcaggtgtt gcatacaaat tagcacaagc attgattgaa aatgtacctg attattttaa
    63541 agcattagtt gcgataggta ccattgcgga tttagtatcc ttaactgatg aaaatcgatc
    63601 attagtgaaa caaggattaa aagtcttaaa tgatcaatgt ccgacctctg ttaaagcatt
    63661 gctaaaagaa gcgggataca atgacaatat tgatgaagaa acaattggtt ttattattgg
    63721 acctagactt aatgctgtag gtcgtttaga tgacgcatca ttagcttgcg aattgttgat
    63781 gactgacgac gaagaagaag ctgcattttt agcagaacaa gttgaacatt ttaaccgtga
    63841 aagaaaagat attgtagcaa ctatcacaga agaagcaatg gctatggcag aaacgaaagt
    63901 taaaaaggga gatttatttt tacttttagc aaaagaaaat tggcatgaag gtgtcttagg
    63961 tattgttgct tcgaaaattg tcgaaacatt tgctttgcca acattaattt taaatattga
    64021 tagggagcaa aatcatgcaa aaggttccgc cagatcaatt gatcaagtgt cgatgtttga
    64081 aatactatca gcacatcaag agttaatcgc taaatttggc ggccatcata tggctgcagg
    64141 tatgacgatg gatattgaaa atatagaatc gttagctgaa ggtttaaata aatggatgaa
    64201 agaattatct aaaacaactt cgttagatcc cgtaaagcca gtagacgtat tattaacaga
    64261 aaatgatata acgattaaaa atattcgtga tatgaatcgt ttaagaccct tcggaacaga
    64321 tttttctaga cctatttttg aaatggatga tttatcagtt tcttcagtta aggcgatcgg
    64381 tcaacaaaaa aatcatctaa aattgacact tggtgaaagt aatatcgccg cgctattttg
    64441 gcaaaatgga cacttagaac ctgagttaca agatgaacag ccaattaata tattaggatc
    64501 tgttcaaatc aacgaatgga atggtaatca atcaccgcaa ttaattattc aagatattgc
    64561 gatgaatgaa cagcaaatat tagattatag aagtaagcga aaaagtttac cttttacaga
    64621 aaatgatgaa aatattgtcg tgcttattca tcctaaaagt gataaagtaa atgcgaatga
    64681 atattattat ggtgaagaaa ttaaacaaca aactgataaa gtagtattaa gagatttacc
    64741 aacgtcaatg gaagacttgt ctaattcctt gcaacaactg caattttctc aactttatat
    64801 agttttgcaa cataatcatt cgatttactt cgatggtata cctaatatgg atatttttaa
    64861 aaagtgttat aaagcattaa taactaaaca agaaacaaat atccagaaag agggtatgtt
    64921 attgtgtcaa catttaagtg tgaaaccaga tacacttaaa ttcatgttga aagttttctt
    64981 agacttaaaa tttgtaacac aagaagatgg tttaattcga atcaatcaac aacctgataa
    65041 aagatcgatt gattccagca aagtatatca attaagacaa caacgtatgg atgttgaaaa
    65101 gcaattatta tatcaagatt tttcagaaat aaaaaattgg ataaagtcac aattgtcgtg
    65161 agcaatttag gaggaaatat taatggattt aaagcaatac gtatcagaag ttcaagattg
    65221 gccgaaacca ggtgttagtt tcaaggatat tactacaatt atggataatg gtgaagcata
    65281 tggctatgca acagataaaa ttgtagaata cgcaaaagac agagatgttg atatcgttgt
    65341 aggacctgaa gcgcgtggct ttatcattgg ctgtcctgta gcttattcaa tggggattgg
    65401 ctttgcacct gttagaaaag aagggaaatt acctcgtgaa gtcattcgtt atgagtatga
    65461 cctagaatat ggtacaaatg ttttaacaat gcacaaagat gcaattaaac caggtcaacg
    65521 tgtgttaatt acagatgatt tattagctac tggtggtacg attgaagcag caataaaatt
    65581 agttgaaaaa ttaggcggta tcgtagtagg tattgcattt ataattgaat tgaaatattt
    65641 aaatggtatt gaaaaaatta aagattacga tgttatgagt ttaatctcat acgacgaata
    65701 ataaataata taattttatc aaatgaaatc cttcatcaaa tgtataagaa ccaatgactt
    65761 aattaaaaaa gttgtttaag ttttcttaac atgagatgtt aggatttttt atttactgaa
    65821 aatgttagat gattgagcat tataccttaa taacatcgtt tatttatttc ataaattgta
    65881 gtatcataga actaatattt aaaaaatgaa acagtagatt taggtcgaat ttttgtaaaa
    65941 gttttaaaag taggaatagt atacaaatta aactcgctca agtgaaatta atattacgat
    66001 taatgacgac aggataaata tttatcgtcg acggacgtat gattggtgtg ggacaaatac
    66061 tattcaacaa gagtacctaa atcattgttt aaggcgaagt aataaatatg aatggggtgt
    66121 atcatataat gaacaacgaa tatccatata gtgcagatga agttcttcac aaagcaaaat
    66181 catatttgtc agcagatgaa tatgagtatg ttttaaaaag ctatcatatt gcttatgaag
    66241 cacataaagg tcagttccga aaaaacggat taccatacat tatgcatcct atacaagttg
    66301 caggtatttt aacagaaatg cgattagacg gaccgacgat tgtcgcaggt tttttgcatg
    66361 atgtaattga agatacaccg tatacatttg aagatgtaaa agaaatgttc aatgaagaag
    66421 ttgctcgaat tgttgatggt gtgacgaagc ttaaaaaagt aaaataccgc tcaaaagaag
    66481 aacaacaagc tgaaaatcat cgcaagttat ttattgcgat tgccaaagat gtacgcgtaa
    66541 ttttggtgaa attagcagac agattacata atatgcgtac cttgaaagcc atgccgcgtg
    66601 aaaaacaaat tagaatttct cgagaaacat tagaaattta tgcaccttta gcacatcgtc
    66661 ttggtattaa tacaattaaa tgggaactag aagatacggc tcttcgttat attgataatg
    66721 tgcaatattt tagaatagtc aatttaatga agaagaaacg tagtgaacgt gaagcgtata
    66781 tcgaaacggc tattgataga atacgtactg aaatggaccg aatgaatatc gaaggcgata
    66841 taaatggtag acctaaacat atttacagta tttatcggaa aatgatgaag cagaaaaaac
    66901 aatttgatca aatttttgat ttgttggcga tacgtgttat tgtcaattct attaatgatt
    66961 gttatgcgat acttgggttg gtgcatacgt tatggaaacc gatgccagga cgttttaaag
    67021 attatattgc aatgcctaaa caaaatttgt atcagtcatt gcatactaca gtagtaggtc
    67081 caaatggaga cccgctcgaa atccaaatac gaacgtttga tatgcacgaa attgctgagc
    67141 atggtgttgc agcacactgg gcttacaaag aaggtaaaaa agtaagtgaa aaagatcaaa
    67201 cttatcaaaa taagttaaat tggttaaaag aattagctga agcggatcat acatcgtctg
    67261 acgctcaaga atttatggaa accttaaaat atgacttaca gagtgacaaa gtatacgcat
    67321 ttaccccagc gagtgatgtt attgagttgc catatggtgc tgtgccgatt gattttgctt
    67381 atgcgattca cagtgaagta ggtaataaga tgattggtgc caaggtgaat ggcaaaattg
    67441 taccaattga ctatatttta caaacaggcg atattgttga aatacgtact agtaaacatt
    67501 catatggacc aagtcgtgat tggttgaaaa ttgttaaatc gtctagtgcc aaaggtaaaa
    67561 ttaaaagttt cttcaaaaaa caagatcgtt catctaatat tgaaaaaggc cgaatgatgg
    67621 ttgaagttga aataaaagag caaggattta gagtcgaaga tattttgaca gagaaaaata
    67681 ttcaggttgt taatgaaaaa tataactttg caaatgaaga tgatttattc gcagctgtag
    67741 gatttggcgg cgtgacatcc ttacagattg ttaataaatt aactgaaaga caacgtattt
    67801 tagataaaca acgtgcttta aatgaagcac aagaagttac gaaatcattg cctattaaag
    67861 acaacatcat tactgatagt ggtgtctatg tagaaggttt agaaaatgta cttatcaagt
    67921 tgtcaaaatg ttgtaatcct ataccaggtg atgatattgt aggttatatc accaaaggtc
    67981 acggtattaa agtacatcgc actgattgcc caaatattaa gaacgaaact gaacgactaa
    68041 ttaatgttga atgggtaaaa tcaaaagacg caactcaaaa atatcaggtt gatttagagg
    68101 taactgcgta tgaccgaaat ggcttgttga atgaagtact acaagctgtt agctcgacag
    68161 ccggcaattt aattaaagtt tcaggacgtt cagatattga taaaaatgca ataataaata
    68221 ttagtgtcat ggtgaaaaac gtgaatgatg tttatcgtgt ggtagaaaag atcaaacaac
    68281 ttggtgatgt ttatacagta acaagagttt ggaactagag gtgcaaaata tgaaagtagt
    68341 tgtacaaaga gttaaagaag catcggtgac gaatgataca ttaaataatc aaatcaaaaa
    68401 aggatattgt ttattagtcg gtatcggtca gaactctaca gagcaagatg cagatgtaat
    68461 tgcaaagaaa attgctaatg caagattatt tgaagatgac aataataaat taaactttaa
    68521 tatccaacaa atgaatggtg aaatactatc agtttcacaa tttactctct atgcagatgt
    68581 aaaaaaaagg taaccgtcca ggtttctcaa attctaaaaa tcctgatcaa gcggtaaaaa
    68641 tttatgagta ttttaatgat gcgctacgag cgtatggtct tactgtgaaa acaggtgaat
    68701 ttggaacaca catgaatgtt agcataaata atgatggtcc agtcactatt atttatgaaa
    68761 gtcaggacgg caaaattcaa tgaaaaaaat agaggcatgg ttatctaaaa agggtcttaa
    68821 aaataaacgt actctaatag tagtgattgc ctttgtctta tttatcatct ttttattttt
    68881 attgctgaat agcaatagtg aagatagtgg gaacatcacg ataactgaaa atgctgaatt
    68941 acgtacaggt ccaaacgctg cgtatccagt catatataaa gttgagaaag gtgaccattt
    69001 taaaaagatt ggtaaagtag gtaaatggat tgaagttgaa gatacatcca gtaatgaaaa
    69061 aggttggata gctggatggc acacaaattt agatattgtc gcggataata cgaaggagaa
    69121 aaatcctttg caaggtaaaa caatagtgct tgatcctggt catggaggta gtgaccaggg
    69181 tgcttcaagc aatactaaat ataaaagttt agaaaaagac tatacgttga aaacagcaaa
    69241 agaattgcag cgtactttag aaaaagaagg cgcaactgtt aagatgacaa gaacagacga
    69301 tacatatgtt tcactagaaa atcgtgatat caaaggcgat gcctatttga gtatacataa
    69361 tgatgcatta gaatcatcta atgcaaatgg aatgacagtt tattggtatc atgataatca
    69421 aagagcttta gcagatacgt tagacgctac gattcagaag aaaggtttac tttctaatcg
    69481 cggttcaaga caagaaaatt atcaagtgtt aagacaaaca aaagttcctg ctgttttatt
    69541 agaattaggt tatattagta acccaactga tgaaacgatg attaaagatc aattacatag
    69601 acaaatttta gaacaagcaa ttgttgatgg acttaaaatt tatttttctg cgtagggctt
    69661 gcaaaaatat gtgaaagtag ttatcattga tattgaattt tataactaaa accgttagta
    69721 ttcttgaaat ggtaaatgaa ataggtagca atctaactaa gattgtgtag gaatataatc
    69781 catagactga aagattatgc tgagtagttt atatacattg aacacaagaa gaggtgcttt
    69841 atgaaaagta aagccgttaa acgtacgtta aacgttttga gtgggtttat ttaatgcacg
    69901 cttataaaaa gtaatgatga ttacaattag gcatgttttt taaaccaatg agggtggcaa
    69961 cacggatatt cgtcccttgt gcagtttcag gctgtgcaag ggctttttct tttgctttta
    70021 aaattatgat ttatcatgca aagttaagtg atcgtatata gttttagttt taaaaaggta
    70081 attaaataaa atagtttgcc gagggagatg tcaaaatgat taaaatacct agagggacgc
    70141 aggatatttt acctgaagat tcaaagaaat ggcgttacat tgaaaatcaa ttagatgaat
    70201 taatgacatt ttataattat aaagaaataa gaacaccaat ttttgaaagt acagatcttt
    70261 ttgcaagagg tgttggtgat tcaaccgatg tcgtacaaaa agaaatgtat acatttaaag
    70321 ataaaggcga tagaagtatt acattaagac ctgagggaac agctgcagtt gtgcgttcat
    70381 atattgaaca taaaatgcaa ggtaatccaa accaaccaat taaactttat tacaatggac
    70441 cgatgtttag atatgaacgt aagcaaaaag ggcgctatcg tcaatttaat caatttggtg
    70501 tagaagctat tggtgctgaa aatcctagcg tagatgcaga agtattagct atggttatgc
    70561 atatttatca atcatttgga ttaaaacatt taaagcttgt tattaatagt gtaggggata
    70621 tggcgtctcg aaaagaatat aacgaagcgt tagtgaaaca ctttgaacca gtaattcatg
    70681 aattttgttc agattgtcaa tcacgtttgc atacaaatcc gatgcgaatt ttggattgta
    70741 aagttgaccg tgataaagaa gcgattaaga ctgcacctag aatcactgat ttcttaaatg
    70801 aggaatctaa ggcatattat gaacaagtaa aagcttattt agatgattta ggtattccat
    70861 atattgaaga tcctaactta gttcgtggat tggattatta tacacataca gcatttgaat
    70921 taatgatgga taatcctaac tatgatggtg ccattacaac gctttgtggt ggtggccgtt
    70981 ataatggttt attagaattg ctagatggtc caagtgaaac aggtattggt tttgcgctaa
    71041 gtatagaacg attattgctt gcacttgaag aagaaggtat cgaattagat attgaagaaa
    71101 acttagattt attcattgtt acaatgggtg atcaagcaga tcgatatgct gtgaagttat
    71161 taaatcattt gagacataat ggtattaaag cagataaaga ctacttacag cgtaaaatta
    71221 aaggacaaat gaaacaagca gaccgtttag gtgccaagtt tacaatcgtt attggtgatc
    71281 aagaattaga aaataataaa atcgatgtta aaaatatgac aactggtgaa tctgaaacaa
    71341 ttgaattaga cgcattagtc gaatatttta agaagtagag agggcgttaa aatatgagta
    71401 agagaacaac ttattgtgga ttagttactg aagcattttt aggacaagaa attacattaa
    71461 aaggatgggt taacaatcgt cgtgacctag gtggattgat tttcgttgat ttaagagata
    71521 gagaaggaat tgtacaagtc gtgtttaatc ctgcattttc agaagaggca ttgaaaattg
    71581 ctgaaacagt acgttctgaa tatgttgtag aagttcaagg tacagttacg aagcgtgacc
    71641 ctgaaacagt taatcctaaa attaaaactg gccaagttga agtacaagtt acaaatatta
    71701 aagtgattaa taaatctgag acaccaccat tttctataaa tgaagaaaat gttaacgttg
    71761 atgaaaatat tcgattaaaa taccgttatt tagatttacg tcgtcaagag ttagcgcaaa
    71821 catttaaaat gagacatcaa attacacgtt ctattcgtca atatttggat gatgaagggt
    71881 tctttgacat cgaaacacca gtactaacga agtcaacacc tgagggtgca cgtgactatt
    71941 tagtaccatc tcgtgttcat gatggtgaat tttatgcatt accacaatca ccacaattat
    72001 ttaagcaatt attgatgatt agtggatttg acaaatacta ccaaatcgta aaatgcttcc
    72061 gtgacgaaga tttacgtgca gatcgtcaac ctgaattcac acaagtcgat attgaaatga
    72121 gttttgtaga tcaagaagat gtgatgcaaa tgggtgaaga aatgcttaaa aaagttgtta
    72181 aagaagttaa aggcgttgaa attaatggcg ctttcccacg catgacatat aaagaagcga
    72241 tgcgtcgcta tggttctgat aaaccagata cacgttttga aatggaatta attgacgttt
    72301 ctcaattagg acgtgatatg gactttaaag tatttaaaga tactgttgaa aatgatggtg
    72361 aaattaaagc aattgtcgct aaaggtgcag ctgaacaata tactcgtaaa gatatggatg
    72421 ctttaacaga atttgtaaac atctatggtg ctaaaggatt agcgtgggtt aaagttgtgg
    72481 aagatggttt gacaggtcca attggacgtt tctttgaaac agaaaatgtt gaaacattac
    72541 ttacattaac tggtgctgaa gctggtgact tagtaatgtt tgttgcagac aaaccaaatg
    72601 tcgttgcaca aagtttaggt gcattacgtg tcaaattagc taaagaatta ggtttaatcg
    72661 atgaaacaaa attaaacttc ttatgggtga cagattggcc attattagaa tatgatgaag
    72721 atgcgaaacg ttacgttgca gcacatcatc catttacatc tccaaaagaa gctgatattg
    72781 ctaagcttgg cactgcgcca gaagaagctg aggcaaatgc ttatgacata gtattaaatg
    72841 gttatgaatt aggtggcggt tcaatcagaa ttcatgatgg tgagttacaa gaaaaaatgt
    72901 tcgaagttct tggatttact aaagaacaag cacaagaaca gttcggcttc ttactagatg
    72961 catttaaata tggtgcacca ccacatggcg gtattgcatt aggattagac cgattagtca
    73021 tgttattgac taatagaaca aacttgagag atacaatcgc attccctaaa acagcatctg
    73081 ctacatgttt attaacgaat gcgcctggtg aagtttctga taaacaatta gaagaacttt
    73141 ctttgcgaat tcgtcactaa attttaaaaa atcaataaac tttggtttgt tataatttca
    73201 ttaattttaa ttatgtggta atataacatc ataagatagt catctgagtt gttcgtaagt
    73261 ttgcttttta atttgggcct aacactcttt gatcaaggga gcccaatggg ttttcttgca
    73321 gcgtacacgc cttatatgaa ggacgtacaa aacaagaaac agggcaccca cctgtatata
    73381 acaggccgaa tgatcaagct attataacta cggcaatacg gactctatcg atacgcaaga
    73441 ctttgtcttg cgtattttta tgcgtttctt taagttttta ataaagaatt agttgggttt
    73501 tatagcgttt aataaatgtt tcctcgttga attttgggaa aataatcaaa gcgataatgc
    73561 taaatataaa attttaagtt actatgtact tatgtataaa tcagtgaaag aggtaaaata
    73621 atgaaacatc aattttcaag aaatgaacta gcgattggac aacaaggttt agatttattg
    73681 aagcaacaaa ctgttgtcat acttggcgtt ggaggtgttg gttcatttgc tgctgaagca
    73741 ttagcaagaa cgaatattgg tcatattata ttaatagata aagatgatgt tgatattaca
    73801 aatgtaaaca gacaattaca cgctttaact acaacggtag gacaaagtaa agtttctttg
    73861 atggaagaac gtattaaatt aattaatcca gattgtaaag tcacgccctt acatatgttt
    73921 tatacagaag agacatatga agaaattttc gataactacg atatagatta ttttgtagat
    73981 gcaagtgata caataatgta caaagtacac ttaatgaaag agtgtcttga ccgagggatt
    74041 aaagtgattt ccagtatggg tgctgcaaat aaaacagatc caacacgttt tacaatttca
    74101 gatatctcta aaacacatac cgatccaatg gccaaaatta ttcgtcaaaa attgaaaaaa
    74161 ctaggaattc gtaaagggat tccagttgta ttttcagatg aaagtccaat tgtcataaga
    74221 gaagatgtaa aagatatagt tggagataaa aatgctatca atcgaaaagg acaaatgcca
    74281 ccttcttcaa atgcctttgt gccaagtgtt gttggattaa tttgtgctag ttatgtggtg
    74341 aatgacgtat taaaagatat tccagttcgt cgcattaaag acaaagggca ataattcatt
    74401 ttgaaagtca taattttcaa cgtaaggcaa gtgtaaccac accataaaac taaaactgac
    74461 tagttcgcaa gcatagtaga atatgcctcg tgtactagtc agttttgatt tgattatagc
    74521 taaaatatca aaggtaatcg atttaatctt atttttacgg cctttgttta agtaagttgt
    74581 tatatatttc tttgagttgt tgttcacttt tagatgtcgt ttttggttca taataaattt
    74641 tgtttttaag tttatcaggt aaatattgct gtgaaacata gccattaaca tattggtgtg
    74701 gatatttgta accaatagat cggcctagat ctttagcacc ttgataatgt ccatctttta
    74761 aatgatttgg aatttgaccc acatgaccgt ttctaatatc ggacaatgca ctatcaatgg
    74821 cactcattgc tgaatttgac ttaggtgata agcatagttc gattactgct tggcttagtg
    74881 gaattctagc ttctggtaaa cctagacgtt ctgctgattc aatagcagca agtgttctct
    74941 gaccagcatt aggtaaggct aagcctatat cctcatagct aattacaagt aatcgtcgaa
    75001 ctattgtagg taaatctcca gcttcaatta atcgtgctaa ataatgtaaa gcggcattga
    75061 cgtcgctacc acggatagat ttttggaaag cgctcataac atcgtaatgc atgtcaccat
    75121 ccttatcact tacaaatgca cctttttgta aacagtcttt agcatcttgc aatgtaacat
    75181 gtcgataacc gtctttgtca ttatctgcgc ttaatacagc taattccaat gcatttaacg
    75241 cactacgaac atcaccttgg ctttgtgtag aaaagtaggt catggcatct tcatcaattt
    75301 tgggttgata tgttttcaaa ccattctcat catcttctat tgcacgagtt aacgcttggc
    75361 gcacatcttc gtcatttaaa ggatataact cgaaaatttg cgctcttgaa cgaatcgctg
    75421 gattgatagc atgataagga tttgaagttg tagcaccaat caagacgatt ttgccatttt
    75481 ctaaatgagg taataaaaag tcttgtttag ctttatctag tcgatgtatt tcatctaaca
    75541 acaagataac ttgaccagac attttagctt cttcaacaac aagttgcata tcttttttag
    75601 tgttagttac agcattcaat tgtctgaatt tatattgcgt actgcccgaa attgctttgg
    75661 caatacttgt tttgcctata ccaggtggac cataaaaaat cattgaagtt aatttttttg
    75721 tgtcaaccat tcttctgata atgccttttg gtccaactaa atgttgttgg gaaatgattt
    75781 catctatatt ttttgggcgc attctcgatg ctaatggttc tgtactcaca tttgtcacac
    75841 ctttcttata ctatcttaac tcaaaaaatg ctaaaatggg aatatcaata ttcgaattaa
    75901 gtgaggttat acaatgaaaa tttctactaa agggagatat ggacttacat tgatgatttc
    75961 tcttgctaaa aaagaggggc aaggatgtat atcattaaag tcaattgctg aagaaaataa
    76021 tttgagtgat ttatatttag aacagcttgt aggtccttta agaaatgcgg ggttaattcg
    76081 aagtgtacgc ggtgctaaag gtggatacca attaagagta ccagcggaag aaatctcagc
    76141 aggggatatt ataagactgt tagaaggtcc aattacattt gttgaaagta ttgaatcaga
    76201 accacctgcg caaaaacaac tatggattcg catgagagat gcagtgagag atgttttaga
    76261 taatacaaca ttgaaatatt tagcggaata tgtagataca agtgaagatt tagacggata
    76321 catgttttat atttaatcgt ataaatacta tactataaca taaaaacttc atattataat
    76381 gtttagcgaa cctccttagt ggtatataaa tatatacatc caaggaggtt tcactatggc
    76441 agacgaaagt aagttcgatc aatttaaagg aaatgttaaa gaaacagtag gtaacgttac
    76501 tgataacaaa gaattagaaa aagaaggtca gcaagataaa gcgactggta aagcaaaaga
    76561 agttgttgaa aatgctaaaa acaaaataac tgatgcaatt gataaactta aaaaataagt
    76621 tcaattaaac taatcaaata taagaggagc gattaatatg agttttatgg ataaagctaa
    76681 agacgcagta gaaaaattta aaaatagcga taatgaacaa gttaaaaatg taaaagataa
    76741 gataaatgaa tatacaggat cgaataacga agagaaaaaa gaaaatgaag ataaagagaa
    76801 ataaatttct ttaaattttg gatatgcttt tcaatatttt gaaagcgccc catcaaataa
    76861 acactaacac agtgtaaagt tgaaggggcg ctttcatatt tgctttagaa ttttaagtga
    76921 atttgaatca ttactaaaac aaatgattga acaataaaga catcttttat tcaaaatgct
    76981 gttactgttt atttttatta atattatgga tacatacttt cacttagttt atttatcaca
    77041 ttataaagtg tttttttcat ttatctgatt tataacattc ttgaaccgac gataagagtc
    77101 taattgcata tctttatcat aaatataact tattgccata atttcgttga cttcaccata
    77161 agtttccata aaatcttgaa ttttttgttg aacagtattt tctgaaccta ttaatgatat
    77221 tttctgtctt tccatagcca tcgcatattc tctcggcgtt aatatatttt gtagatcatg
    77281 tgttggcggt tgaacgggct gcattctgcc acgagtgata ctaaccatta cttgtgccat
    77341 agatgaagct aaatattgtg cttcgtcatc attttcagca acgattgtat ttaaacatac
    77401 aataacataa ggttcgtcta atacatcaga aggttcaaat aacgttttgt aaatttcgat
    77461 agcttctttc atttgttgag gtgcaaaatg tccagcgaac acatatggaa gccctttgcg
    77521 agcagctaaa tgtgcagaat ctgttgaaga accaagaatg tataaaggca catttttacc
    77581 tactgctgga taagcacgaa catatgcttg ttggtgagct gggccgaaat attgttgtaa
    77641 taatgaaact tcttctggaa atttataaac accatcatgt tgatctcgtc ttaatgcact
    77701 tgcggtcatc atatctgttc caggtgcacg tcctaatcct aaatcgacac gatttggaaa
    77761 taatgttgcc atcgtgccga attgttccgc aacgattaat ggagcatggt taggtaacat
    77821 gattcctcca gaacctacac gtatgtgttt cgtatgttct aacgtatgtt gaatcaataa
    77881 agcagttgct gaacttacta ggttgggagc gttatggtgt tcagcaatcc aatatctttc
    77941 atacgataat tcatctaaat gttgtgcgag cttaaccata tcattaattg ctgttcgttc
    78001 atcgtcacct tctcgaatag ggacaaggtt taatgctgaa tatttaatcg ccatttttat
    78061 atcgtccttc cttttttatg atataagaag tataccaatc gaataaccag ataaatatta
    78121 aattgctcat aaccaaaata atagtacgtt acattttaca aatgaaaaaa tatctgcaaa
    78181 tactaaaatt tataaaaaag acaagaataa agcgataaac ttaaaaaagc ctatcgaaaa
    78241 gcatgtgtag aaaatggtaa aatataatta aaaacattat aaataaagtt aaacagaaaa
    78301 gtagaaaaat agtatgtaag gtgctattat tggaacattg ataaaattgt gaggagtgtc
    78361 caaacatgga aatttatgca gattatgctg cgaccacacc agtaaaacct gaagtagtag
    78421 atgcgatgat gatgatttac aattcgcatt atggtaatcc atcatcaata catgctaagg
    78481 gaagagatgc gcgtaaatat ttagatgagt caagacgtca aattgcacaa ttacttggtg
    78541 cagatacaca tgaaattata tttacgagtg gtgcaacaga atcgaataat acggcaatta
    78601 aaggcatagt aaaagcaaat gaacaattgg gtaatcacat tatcacatcg aagattgaac
    78661 atcattctgt gttacatgtt tttgaacaat tagagcgaga aggttttgat gtaacatatc
    78721 tagatgttga tgatacaggt gctattgatt tagatcaact tgaagaaaca attacagata
    78781 agacgatttt agtatctatt atgtttgtaa ataatgaagt tggcacagtg caacaaattt
    78841 atgatattca agatattatt gctgagacaa atgcatattt ccatgttgat gcggttcaag
    78901 caattggaca tcttgatgtt aagtttgacg aatttgagat cgacgcaatg agtattactg
    78961 cacataagtt tggcggacca aaaggtgtcg gtgcattatt agttaaagac catgtcacat
    79021 tagattatcc tcaacttggc ggtgaacaag aattgaaacg ccgtgcaggt actgaaaatc
    79081 ttgcacaaat tgtcgggatg gctaaagcat tacaattagc agaaaagaat cgagacgata
    79141 acaatattca tttaatgaat ttaaaagaac aatttttagt taaattacaa gaaagagcga
    79201 ttccatttga attaaatggt tcaatgacgg atgctacagg ccatattgta aatctatatt
    79261 ttccgtttgt tgaagttgaa atgatgttaa cattgttgga tatggcacaa atctatgtgt
    79321 cgtctggatc tgcatgtaca gcaggctcta cacaaccgtc gcatgtttta gatgcaatgt
    79381 tcgaagatga ggagcgatca aatcattcga ttcgatttag ttttaacgaa ttgactactg
    79441 aaaatgaaat taatgcaatt gtagctgaaa ttcataaaat atattttaaa tttaaggagg
    79501 agtcataatt gtcaaataaa gatatacgtg ttgtcgttgg tatgtcaggc ggtgtagata
    79561 gttctgtaac agcccacgtc ttaaaagaac aaggttatga tgtcattggc atatttatga
    79621 aaaactggga tgacactgac gaaaatggcg tatgtactgc aactgaagat tacaacgatg
    79681 ttattgaagt gtgtaatcaa attggcattc catattacgc tgttaatttt gaaaaagaat
    79741 attgggataa agtctttacg tatttcttag atgaatacaa aaaaggtcgt actccaaatc
    79801 cagacgttat gtgtaataaa gaaattaagt ttaaagcctt tttagatcat gcgatgaatt
    79861 taggtgcaga ttatgtagca acaggacatt acgcacgcat acatcgtcat gaagatggtc
    79921 atgttgaaat gttacgtggt gtagataata ataaagatca aacatacttc ttgaatcaat
    79981 tatctcaaca acaactttca aaagtgatgt tcccaattgg cgacatcgaa aagagtgaag
    80041 tgcgtcgaat tgctgaagaa caaggacttg ttactgctaa gaaaaaagat tctacaggca
    80101 tttgttttat cggcgaaaaa aactttaaaa catttttatc acaatattta cctgcacaac
    80161 cgggtgatat gataacactt gatggtaaga aaatgggtaa acatagtggt ttgatgtatt
    80221 acacaatagg acaaagacat ggattaggta taggtggaga tggcgatcct tggtttgttg
    80281 tcggtaaaaa cctaaaagat aatgttttat atgtagaaca aggattccat cacgatgcat
    80341 tatacagtga ttacttaatt gcttcagact attcatttgt aaatccagaa gataatgact
    80401 tagatcaagg ttttgaatgt acagctaaat ttagatatcg ccaaaaagat acgaaagttt
    80461 ttgtgaaacg tgaaaacgac catgcactac gtgttacttt tgctgagcca gtaagagcaa
    80521 tcacacctgg acaagcagtt gttttttatc aaggtgatgt gtgtcttggt ggtgcaacaa
    80581 ttgacgatgt gttcaaaaat gaaggtcaat taaattatgt tgtataaaca atggcaacaa
    80641 taaattactt atttgaagtt tcaacgtcga aaatgacgaa agacagtttt tgatgagaat
    80701 aattcatgat gatagagtct gggacatcac aatgtcctag gctctacaat gttatattgg
    80761 cggggcccca acatagagaa tttcgtaaag aaattctaca ggcaatggaa gttggggacg
    80821 gggccccaac atagagaaat tggaacccca atttcaacag gcaatggaag ttggcggggc
    80881 cccaacacag agaaattgga accctaattt caacaggcaa tggaagttgg ggacggggcc
    80941 cccaacatag aagctgacca aaagtcagct ttcaataatg tgcaagttgg ggatggggcc
    81001 ccaacacaga gaatttcgta aagaaattct acaggcaatg ccagttgggg ataacgaatt
    81061 taattttgtt aaaatatcat ttctgtccca ctccctatgc atgaatctaa ttatgtattc
    81121 ctatttttaa gtacataata gtggtggcta atgtggaaga accattacat aataaaccgt
    81181 taatggttct ttagcatttc tattccattc ccgctttttc atgaatgaaa atgatattag
    81241 attatatttt attcgttgtt aagtgattcg agacatacaa tttatcaaga tgttataatt
    81301 gatgagaaat gaggttcgta aatgatagat caacaaacaa tttatcaata catacaaaat
    81361 ggaaaaatag aagaagcgtt acaagcattg ttcggaaata tcgaagaaga tcctacaatt
    81421 attgaaaatt atattaatgc tggtatcgta cttgctgatg cgaatgagat tgaaaaggca
    81481 gagcgttttt tccaaaaagc tttaacaata gatccgaaga atggcgtcgt attttataat
    81541 ctagcaaatg tatattataa tcagcaacgt tatcaagaag ctattaaatt atatcaacaa
    81601 gcattacaaa cagagattga acaagttgat tgtaattata tgatcggtat ggcgtttaat
    81661 cagttagaat catttaagct ggcattgccg tatttaatga ctgctgcgga actagataaa
    81721 gacaaagatg cagaagttca atttcaatat ggtcttgtat tatgtcaatt agaaatgttt
    81781 aatgaagcca taactcaact taaacatgta ttaacgattg ataaaaatca tgttgatgca
    81841 agatacaatt tgggcttagc gttatttatg aaaaatgaag atattgatga agcaataact
    81901 cattttaaag aagctgtgac tatcgaccct aaacacttat taagtcagca tgcgctgaaa
    81961 acattcacta aaatgaaaga ggaggagtaa catgtcagac cctacactat ttgattattc
    82021 aatgatcaaa ggtactgttg aagcgatatt gtttcaaaac agtgataatt tttatacagt
    82081 gcttaaagta gatactattg aaacaaatga agactttgat acaatgccaa ctgttgtagg
    82141 gtttcttccg aatattgttg aaggcgatgt ctacacattt aaagggcaag ttgttgatca
    82201 tccacgttat ggtaaacaat taaaagcaga gacttttgaa aaagaaatgc cacaaacgaa
    82261 agaagcaatt ataagttatt tatctagtga tttgtttaaa ggtgtaggta aaaagacagc
    82321 tcaaaatatt gttaatacat taggtgacaa tgcgataaat gatatattag atgaccattc
    82381 agtgctagaa aaagtttcgg gattatctaa aaagaaacag aaacaaattg cagaacaaat
    82441 ttcagcaaat caagaatctg aaaaaataat gattcgttta catgatttag ggtttggtcc
    82501 taaactttca atggcaattt atcagtttta tctcggcgat acactgacta ttttagatcg
    82561 aaatccatat caattgattt atgatattaa aggtattggt tttaataaag cagatcaact
    82621 tgctagaaat attggtatcg cttataacga taatgaacga ttaaaagctg cgttgctcta
    82681 tacgttagaa gaagaatgta ttaaacaggg acatacatat ttgcctatca atgttgttat
    82741 agatttaacg gttgatgtat taaattatca agatgaagag gtcatcgaac ctgaaaaatt
    82801 agacgaaatg ttgcaatact taaatgagga aaaacgacta attattgaca atgaacaagt
    82861 tgcaattcca agtttgtatt attctgaaat caaaagtgtt caaaacttat tcagaataaa
    82921 gacgcataca aataaactta cggaaattga acagtcagat ttacaaatgc atattggtga
    82981 aatagaagat gcgaatcaag tgaactatgc agcttcacaa aaagaagctt tgcaaacggc
    83041 tatcaattct aaggtgatgc tattaaccgg tggaccggga acaggaaaga cgacagtaat
    83101 taaaggtatt gtagaattat atgctgagat tcatggctta tcattagatt atgatgatta
    83161 tgtcaatgat gattatccag ttgtattagc agcgccaaca ggaagagcgt ctaagagact
    83221 acaagagtca actggattag aagcaatgac gattcatcgt ttaataggtt ggaatcaaga
    83281 cacaaagcca gaggatatat tagaaaatga aataaacgca cgactcataa tcattgatga
    83341 gatgtctatg gtagatactt ggttgtttca ccaattttta agtgcagttc ctttagatgc
    83401 acaattgata tttgtaggtg atgaggacca attgccttct gtaggtcctg gtcaagtatt
    83461 taaagattta attgaatcga aagctatacc acgagttaat ctgactgaag tatatcgtca
    83521 acaagatggt tcaagcatta tagaattagc acatcgaatg aaattgggtc agaaaattga
    83581 tattacacag cgttttcatg atagaagttt tattaactgt caggcaaacc aaataccaac
    83641 agttgttgag aaggtagtta ctagtgctgt taataaaggg tatactatgg ctgatattca
    83701 agtgcttgca ccaatgtata aaggaaatgc cggtattaaa cgtttaaatc aagttttaca
    83761 agatatttta aaccctaaaa agaaagacac acgagaaatt gagtttggtg atgtagtctt
    83821 tagaaaaggt gacaaagtat tacaacttgt taataggcca aatgataaca tattcaatgg
    83881 tgacatagga gttattgttg gtattttttg ggcgaaagaa aatgccctta ataaagatgt
    83941 acttgttgtg gattttgaag gtaatgaaat tacatttacg aaacaagata tgatggaatt
    84001 aacacatgct tattgtacat caatccataa atcacaaggt tcagaatttc ctattgttat
    84061 catgcctatt gttaaacagt attttagaat gttacaaaga ccgatattat atactggttt
    84121 aactagagcg aaaacgagtt tagttctact tggtgatcca gaagcatttg atattggatt
    84181 aaaaacaaat ggtcaagcgc gtttaacaca attatgtaca ttgttgaaaa attattttaa
    84241 ttcagaagat gaagaaatgc tggaaaacac agcaactaat gatacaggag cttcacaaac
    84301 gacaatagat gatcaagtag aagcgccaat gtcatcgaat gatagtggag aagttacgtc
    84361 tgattcaaca aaaacagata taaatgtatt aacggaagct acaatgttta aaattgaccc
    84421 aatgattaat atgggagaaa tcacgccgta tgactttata gaacgttgac aacaagcgta
    84481 aatgtaacta aaatagaatt aaattcgtat aaagatgagt agttaatgat ttgtttatca
    84541 gagatgtact ggttggtgaa aagtacaaca aacattagtg aacgctactt tatgcacaac
    84601 tgtatagtcg atttaaagtg ataaatgtgt tgaattgcat ttataactag ggtggtaccg
    84661 cgataacgtt cgtccctttt gaggatgggc gttttttatt ttttaataat aaaaaatgat
    84721 attgatttat actagttttt caaatcgact atctgtgtca tcaattttta tggaatggta
    84781 atttaaaaac agtaaatagg atgtgtaaaa gatgaaaaag ttaaaagcga gtgaaattag
    84841 acaaaaatat ctagatttct ttgttgaaaa aggacatatg gttgaacctt ctgcaccatt
    84901 agtgccaatt gatgatgata cattattatg gattaattca ggtgtagcaa cattaaagaa
    84961 atattttgat ggacgtgaaa cacctaaaaa gccaagaatt gtaaactctc aaaaagctat
    85021 tcgtacaaat gatattgaaa atgttggttt cacagcgcgt caccatacat tctttgaaat
    85081 gttaggtaac ttctcaattg gtgattattt taaacaagaa gcgattgaat ttgcttggga
    85141 atttttaacg agtgataaat ggatgggtat ggagccagat aaattgtacg ttacgattca
    85201 tccggaagat atggaagcat ataacatttg gcataaagat attgggcttg aagaaagtcg
    85261 tattattcgc attgaaggta acttctggga tattggtgaa gggccttcag gaccgaacac
    85321 tgagattttc tatgatcgcg gagaagcata tggacaagac gatccggcag aagaaatgta
    85381 tccaggtgga gaaaatgaac gctatcttga agtatggaac ttagtattta gtgaattcaa
    85441 tcataataaa gatcatagtt acacaccatt acctaataaa aatattgata ccggcatggg
    85501 gcttgagcgt atggcctcag tttctcaaaa tgtacgtact aactatgaaa cagatttatt
    85561 tatgcctata atgaatgaaa tcgaaaaagt atcaggtaaa caatatttag taaacaacga
    85621 acaagatgtg gcatttaaag taattgctga ccacattcgt acgattgcat ttgcaatttc
    85681 tgatggtgca ttacctgcca atgaaggtag aggatatgta ttacgtcgat tgttacgtcg
    85741 tgccgttcgt tttagtcaaa cgttaggaat caatgagcca tttatgtaca aacttgttga
    85801 tattgttgca gacattatgg aaccatatta tccaaatgtt aaggaaaaag cagatttcat
    85861 taagcgtgtt ataaagtctg aagaagaacg attccatgaa acattagaag atggtttagc
    85921 gattttaaat gaattaatta aaaaagctaa agcgacaaca aatgaaatta atgggaaaga
    85981 tgcatttaaa ttgtatgata cgtacgggtt cccaattgaa ttaactgaag aaatagcagt
    86041 gcaagcagga ttgaaagttg atatgacaac atttgagtca gaaatgcaac aacaacgtga
    86101 tcgtgcacgt caagcacgtc aaaattctca atcaatgcaa gttcaaagtg aagtattgaa
    86161 aaatattaca tctgcaagta cttttgttgg ttatgatact gcgacagctc aaacaacact
    86221 aacacacttg atatataatg gtgaagaagt ttcacaagtt gaagcgggtg aaacagtata
    86281 cttcatgtta acggaaacac cattttatgc agtcagtggt ggacaagttg cggatacagg
    86341 tattgtttat aatgacaatt ttgaaattgc tgttagtgaa gtaaccaaag caccaaatgg
    86401 tcaaaacttg cataaaggag tagtacaatt tggccaagta aatgttggcg ctacagtgtc
    86461 tgctgaagtg aaccaaaatg atcgacgtga cattcaaaag aaccatagtg caacacattt
    86521 attacatgca gcgttgaaat cagtactggg tgatcatgtt aaccaagctg gttcactagt
    86581 agaagcagat cgtttacgtt ttgatttctc tcattttggt ccaatgacta atgatgaaat
    86641 tgatcaagtt gaacgcttag taaatgaaga aatttggaaa ggtattgacg ttaacattca
    86701 agaaatggat attgcttcag ctaaagaaat gggcgcaatg gcattattcg gtgaaaaata
    86761 tggtgatgtt gtgcgtgtag taaatatggc accattttca attgaattat gtggtggtat
    86821 tcatgtccgc aatacttctg aaattggctt attcaaaata gtaagtgagt caggtacagg
    86881 agctggtgtg cgtcgtattg aagcattaac aggtaaagca gctttcttat atttagaaga
    86941 tattcaagag aaatttaata cgatgaaatc acagatgaaa gtgaaatctg atgatcaagt
    87001 agtcgaaaag ttaacacaat tacaagatga agaaaaagca ttattaaaac aattagagca
    87061 acgtgacaaa gaaatcacat cacttaaaat gggtaatatt gaagatcaag ttgaagaaat
    87121 caatggctat aaagtattgg ttactgaagt ggatgtacca aatgcgaaag caattcgctc
    87181 gacaatggat gattttaaat ctaaactaca agatacaatt atcattcttg caagtaatgt
    87241 tgatgataaa gtatcgatgg ttgcaactgt ccctaaatct ttaacaaata acgttaaagc
    87301 cggtgatctt atcaaacaaa tggcaccaat cgttggtggt aaaggtggcg gtcgtccaga
    87361 tatggctcaa ggtggcggta cacaacctga aaatatctca aaatcattaa gctttattaa
    87421 agattacatt aaaaatctat aatttaaagc cataatattg tatgatgata gttagttata
    87481 tttgtaatta aaggagtgtc gcaaatggaa aactttgata aaacaatgaa attcgactat
    87541 gaagaacttc caacgcaaga tgtaagagat gttttaaata atgtttatcg aacattagat
    87601 gaacgaggat ataatgccgt aaaccaaatt gtaggttatt tattatcagg tgaccctgcg
    87661 tatattccac gccagaatga agcaagaaat caaattcgtc atattgatag agatgttatt
    87721 atggaagaac ttgtttctta ctatttaaaa gagcaaaata aataatttat gttacaacat
    87781 aaaattttag gactcgatgt cggtagtaga acggtaggaa ttgcaattag tgatataatg
    87841 ggttggacgg cacaaggatt agacacactc cgaatcaatg aagaaaataa tgaattaggt
    87901 attgaccaat tagtagacat tattaaaaaa cataatgtgg gtacagtcgt aataggacta
    87961 cctaaaaaca tgaataattc aataggattt cgaggcgaag cttcgttaac atataaagaa
    88021 aaattattag aagcttatcc ttctattgag attgtgatgt gggatgaaag attaagcaca
    88081 atggctgctg aacgatcatt attagaagca gatgtttcaa gacaaaaaag aaaacaagtg
    88141 attgataaaa tggcagcggt atttatttta caaggctatt tagattcact acattaaaag
    88201 gagattttac tatgactgaa cataatcatg attcacaact agaaattaat aacgaagaag
    88261 aattattaac tttattcgat gaagagggaa atgaagtttt ataccgaaaa gttttagaat
    88321 tttatcatcc tgaattcaaa aaagagtatg ttatcttagc tgaagaaggt gctcaatcag
    88381 atgaagacga tatgattgag cttgtaccaa tgatcaatga accagatgag tcaggtgacg
    88441 gtggtaagtt agtaccaatc gaaactgatg aagaatggga catgattgaa gaagttgtaa
    88501 atactgaaat ggaagaataa ttaaaaagat tttactcttg ctaaccttaa gatgggtagg
    88561 caagagtatt tttttaagtc aagcaatgta taaataatta acgcttataa ttttattgaa
    88621 aatatggtaa aatatctaaa gttaaatttt atatgaatga ttcgcttcta taaataaaat
    88681 agctttgcgt ctaacaagaa atcagtcatt taattggttg gcaaaattat aatcaattgt
    88741 gaaggctgat ttattttatt gtcataatca tattgactta ttttacataa aggaagttta
    88801 aaacatggat gacctaaata aaaaatattt aatagattta catcaacatc aaaatagttc
    88861 aatcgaagtt ttgcgtgaat ttgccgaggg aaatgaagtg ccaattgtag atcgtttaac
    88921 attagattta attaagcaat taattcgtat gaataatgtt aaaaatattt tagaaattgg
    88981 tacagcaatc ggctatagtt ctatgcaatt cgcttctata tctgatgaca ttcatgtcac
    89041 aacgatagag cgtaatgaaa cgatgattca atatgctaaa caaaatttag ctacttatca
    89101 ttttgaaaac caggttcgaa ttattgaagg taatgcttta gagcaatttg aaaatgtaaa
    89161 tgacaaagtt tatgatatga tatttattga tgcagcaaaa gcgcaatcaa agaaattttt
    89221 tgaaatatat acaccacttt taaagcacca aggtctcgta attacagata atgttttata
    89281 tcacggtttt gtatcggata ttgggattgt tagatcgaga aatgtaagac aaatggttaa
    89341 aaaggttcaa gattataatg agtggttaat aaagcaacca ggatatacaa cgaatttttt
    89401 aaatatagac gatggattag cgatttcaat taaaggagaa tgactatgac agaattactt
    89461 gtcacaccca agtcattaag ccatatggaa acacttattg atttaggtgc agatgctttt
    89521 gtaattggcg agcaaaagtt tggtttaaga cttccagggg aattcaatag acaacaaatg
    89581 acagaggctg tcgcattagc tcacaaaaac gataaaaaag tatatgcggc agtgaatgga
    89641 ttatttcata attatcattt agatgctgta gaagattata ttaatttttt acatgaaata
    89701 cgagttgaca gaattatttt cggggatcca gcagtagtaa tgtatgtgaa ggcgcaagaa
    89761 aatccaatac cacttcattg gaatgcagag acgttagtaa ctaatcattt tcaatgtaat
    89821 tactggggta aaagaggcgc atcaagagct gtcttagcac gtgagctgaa tttggatgaa
    89881 attattaata taaaagaaaa ttcaaatgtg gaaattgagg tgcaagttca aggaatgact
    89941 tgtatgttcc aatcaaagcg tatgctacta ggcaattatt atacgttcca agatcgccaa
    90001 atgaaaattg aacgtcgcaa tgatgaacaa tctttattac tttatgatga agaaagacaa
    90061 aataattacc cagtttacga agattacaat ggtacgcaca ttatgtcacc aaacgacatt
    90121 tgtttaattg aagaattagc accatttttt gaggcgggta tagattcatt taaaatcgat
    90181 ggtattctac aaacggaaga atatattaat gtggtaacgg aacagtatcg tcaagcgata
    90241 gatttgtaca atgaagatcc tgaaatctat gaagatgaga aatttatgtt gattgatcca
    90301 attgaagaaa ttcaacctga tcatcgacca tttgacgaag gtttcttata taaacaaaca
    90361 gtatattaag gaggttaatc atgaagacaa tagaagagat taaatcaact cctaaaacag
    90421 ttatgaagaa accagaatta ttagcacctg ctggaaactt agaaaagtta aaaatagcag
    90481 tacattatgg cgctgatgcc gtatttttag gtggtcaaga atatggatta cgttcaaatg
    90541 ctgataattt cacgatggaa gaaatagctg aaggtgttga atttgcgaac cgttacggtg
    90601 ccaaaattta tgttacgaca aatattattg cacatgatga gaatattgaa ggtctagaat
    90661 catatttgcg taatttggaa aagactggtg cgacaggtat cattgttgca gatcctttaa
    90721 ttatcgaaac atgtaaagaa gttgcgccaa aacttgaaat tcatttatct actcaacaat
    90781 cactttctaa ttacaaagct gtagaatatt ggaaagaaga aggattggat cgtgttgtat
    90841 tagcacgtga gaccggcgcg atggaaatgc gtgaaatgaa ggaaaaagta gatattgaaa
    90901 tcgaagcatt tattcatggt gctatgtgta tcgcctattc aggtagatgt acattaagta
    90961 atcatatgac tgcaagggat tccaacagag gcggttgctg tcaaagttgc cgttgggatt
    91021 atgaattatt agaagttgat gataatggtg aacttgatgt attttataat caaggtgaag
    91081 ttacaccgtt tgcgatgagt cctaaagatt taaaattaat cgaatcaatt cctcaaatga
    91141 tggatattgg tgtggactca ttaaaaattg aaggacgtat gaagtcaatt cattatattg
    91201 caacagttgt ctcagtatat cgtaaagtca ttgatgcgta tgcggcagat cctgacaact
    91261 ttaagattaa tccggaatgg ttaattgagt tagataaatg tgcaaataga gacactgcac
    91321 cagcattctt tgagggaaca cctggttatg aagaacagat gtttggtcaa caacaatcta
    91381 aaaaatcacc atttgatttt tgtggtttgg tattagacta taatgaagat acaaaaattg
    91441 cgactattca acaacgaaat aactttaaac caggtcaaga aatagaattc tttggtccag
    91501 aaattgaaac atttacacaa gtagtagaag caatttatga tgaagaaggt aacagcttag
    91561 acgcggcgcg ccatccatta caaatcgttc aaattaaagt ggatcgcccg atatatccaa
    91621 acaacatgat gagaaaggaa attggctaat gaaagctact acaatcattg gcatagctgg
    91681 tggatctggc tcaggaaaaa caactgtaac taacgaaatt atgaaaaact tagaaggtca
    91741 tagtgtcgct ttacttgctc aagattacta ttataaagat caaaagcact tgactttcga
    91801 cgagcgccta gaaaccaatt atgaccatcc atttgcattc gataatgatt tattaattga
    91861 aaatcttaaa gacttgaaaa atggtaaagc agtagaagta ccgacatatg attatgctag
    91921 tcatacaaga agtgacatta ccattgattt taaacctaaa gatgttatta tcgtagaagg
    91981 tattttcgct ttagaaaata aggtattacg tgatatgatg gatgttaaaa tatatgttga
    92041 tacagatgca gacttgagaa tattacgccg tttaacacga gatactaaag agcgtgggcg
    92101 ttcaatggac tctgttatca atcaatattt aagtgttgtt agacctatgc atgaccaatt
    92161 tattgaaccg actaagaaat atgctgatat aattattcct gaaggtggga gcaataaagt
    92221 tgcaatagat attatgacaa caaaaattca gtctttagtt agcaagcaat agtataattc
    92281 agtaaaggaa gatgacaata tggaaaatca aaagcaatat ccaatgactc aagaaggttt
    92341 tgaaaaatta gagcgtgaac ttgaagaatt aaaaacagtt aagcgtcctg aagttgtaga
    92401 gaaaattaaa gttgcacgtt catttggtga cttatcagag aactctgagt atgatgcagc
    92461 aaaagatgaa caaggattca tcgaacaaga tattcaaaga attgagcata tgttaagaaa
    92521 tgcattaatc attgaagata ctggagataa caacgttgtt aaaattggta aaacagtaac
    92581 gtttgtagaa ttaccaggtg atgaagagga aagttatcaa atcgttggtt cagctgaatc
    92641 agatgcattt aatggtaaga tttcaaatga atcaccaatg gctaaagcgt taattggtaa
    92701 aggtttagat gatgaagttc gtgttccact acctaatggt ggcgaaatga acgtaaaaat
    92761 tgttaatatc caataaatga tcaaatagat tgtttaattg cgcgattgaa gtgtgttaat
    92821 gatacttcgg tcgtgctttt ttatattcaa aatcaaaaaa tcggacagat gaaaagtaaa
    92881 aattttccat cagaccgaat gatagcagaa cctaaattag tgtaagagtt acaatattaa
    92941 ctactccatt ttaaaaaagc aaaatatttc cgagaaaaca aattgattat catttgttat
    93001 tgtatgcgat ttgaattact tattaaacaa cttgtgcttc tcaatgatac aatgaaaagg
    93061 tattcaatac tggtttattg caatacaaag ggggatttaa agtggatgta agatttatta
    93121 acgagcagac aattatgatt tattttgaaa ataaaatatc cgaagagaca tatcgtaatg
    93181 tcacagcaat ggtacggtgg atacgagaaa aagaaatatt agaaattcaa gatattgtcc
    93241 cttcgtatcg agcagttcta atatattttg atgaacaagc tataacatct tctaaattaa
    93301 ttgaaaattt agaacttaac aaatttaatg aaaaaaatgt tcatgctgtg aatcaaacca
    93361 atcgtattat taaaatacct gttcaatatg gtggtacata tggaccagat attgaagaag
    93421 tagcaaagca taatcgaata actgttgagc aagttattga aaaacataca agtaaacctt
    93481 atttaatata tatgctagga tttatgccag gatttccata cttaggcgga cttgatgaac
    93541 aactacatac acctagacgt aatcagccaa ggttaaaaat tcatgcaggt tctgtaggta
    93601 ttgcgaataa tcaaacagga ctatatccat cagattctcc tggcggatgg caaattattg
    93661 gacgcacacc gttaaaagta tttagcagcg agcgtgaacc aatgtcaatg tacgaagcag
    93721 gagaatggat acaattttat gcaatagatg aacagaaatt tatacaaatc gaaagagata
    93781 tatcagatgg caactttaat gttgatgact gggtggtgat tgaaaatgtc aattaagatt
    93841 ttacaaccag gtctcttttc aacggtacaa gatctaggaa gaataggtta tgaacatatt
    93901 ggattttcag gcgcaggtgc catggatcaa tttagtttta aggttgcgca gtcattaatt
    93961 aacaatgatg gtccagcgat tgaatatact ttgattggtc ctaccattca atttaatacg
    94021 caaaatacat ttgttataac cggtggtagt attaatgctt cgctaaataa taaaactata
    94081 tcaatgaatt ctgtcatatt agctgagaaa ggtgacattt taaaaatagg tgctataacc
    94141 aaaggtgtac gcggttatct tacttttggt cattctatca acgtaccttc tattgctgaa
    94201 agttatgcaa cacatacccg aagcagtata ggaggattca aaggtagaaa gttattagct
    94261 aatgatgtaa taacagtgaa aataaataat gactttaaag aaaacattgg aaagactatt
    94321 catttacagg acgatttatt gccagaaaat aatattatac acattcttca aggacctcaa
    94381 ttcgaggcat tttctgaaga ggctagagcg aaaattgtaa atcatccata tttaattact
    94441 gaacaatcag accgtatggg ctatcgtttg gaaggtgaca gcgttgcacc aattaatcaa
    94501 gcagatatca tttctgaacc ggttgctctt ggtagtgttc aagtaccaaa tgatggtcaa
    94561 cctattattc tgcttaatga taaacaaacg ataggtggtt ataccaaaat tgcaactgta
    94621 tgcaaatttg atctgccaaa gttagcacag atgaaaccaa aagatacaat tcaatttaaa
    94681 tggatatcat tccaagaagc tgtagataag aatcgggaac aaatgtctct gtttaatgaa
    94741 attcttaaga gtcatcaaaa gactccaatt tttgatacat ctagcttgcg acatacttcg
    94801 aaaaaattat caacaatttt aaaaggggat ttgtaaaatg aatattgaaa aaatcgaaca
    94861 aataatcaaa ttagtgaagg aaaatgatgt taagaaattt aaatataaaa attttgaaga
    94921 tgaaatagaa attgacttca ctgactcgaa tcatttggct gcacacagta atcaatcaaa
    94981 tcaaagtatg aacaataatg atttgacagc ttcaaaagcg aatgataact ccgatgtttc
    95041 gacaaatgat tatcatgaca ttaaatcacc aatggtaggt acattctttt tacaagatag
    95101 taaagaatta actgaaccaa ttgtgaatgt cggtgacaaa gttaacaagg gagatattat
    95161 aggatatgtt gaagcgatga aagtattaaa cgaggtaaca acagatgttg ctggagaaat
    95221 tactgaaata gtagctgatc atggcacaaa tgttgaatac gaccaagttt tggtacgtat
    95281 taagtaaagg gggtaagtaa atgcttcgtt gtttaattgc gaacagaggt gaaattgctg
    95341 taaggattat aagagcttgc agagaatatg ggattgaaac tgtagcagtt tatgcaaaag
    95401 gggacgagca aagcttgcat gtacatttag cagatcaagc tatatgtatt ggggaagcta
    95461 atgctttaga tagttattta aatattgacc gcatcatatc tgctgcacaa atcactggtg
    95521 ctaatgcaat tcacccagga tatggctttt tatcagaatc aacaaaattt gctcaaaccg
    95581 ttgaggaaca aggcatagcg tttatagggc ctactaaaaa aacgatggaa atgatggggg
    95641 ataaaataac agcaagacaa acagttcatc atgcaggtgt tcctgtgatt ccaggatcaa
    95701 atggtgctgt gaatcatgtg tctgaaattg agaatcttgc caaagacatc ggttatccag
    95761 ttgttatcaa agctgccagt ggcggtggtg gtaaaggtat acgtattgta aagaaagctg
    95821 aagatttaga aaaggcattt aaagaagcta aaagtgaagg aaaaaaatac tttgatgatg
    95881 atcgtgttta tgttgaggct tttatacctg ttgcaaaaca tgttgaagtt caagttatgg
    95941 gagatgggca ggataattat gtacatttag gggaacgtga ttgttctgta caacgtaaaa
    96001 atcaaaaatt aatcgaagaa tctccttgtg cagcattaac tgaagaacga cgacaacaaa
    96061 tatgtaacga tgctgttaaa gttgcacgtg cagcaaatta tagaagtgca ggtacgattg
    96121 aatttttagt aactgatacc gcacattact ttattgaaat gaatgctcga atacaagttg
    96181 aacatactgt tacagagatg cgagcagaac gtgatttggt tgcagcacaa ctgtatttat
    96241 tggaacataa tcatttacct ttttcacaaa gcgatattca atttaatggt catgtgatag
    96301 aagcgagaat aaatgccgaa aatcctgaaa agaaatttca accaacacca ggtaaagtga
    96361 cagcgttaca tttacctcaa ggctttaatg tgcgagtcga ttctttacta tatcacggtt
    96421 atcaagtttc accatattat gattctttag tagctaaagt aattgtaaaa tctcatgata
    96481 gagcttcagc aattgataag ttgaaagtca ccttagatga aatggtgata gatggatttt
    96541 ctacaactgc cgatttttta tatgcagttt taaattatcc actatatcgt gatggagatg
    96601 caaaagatgt tgatattaaa tttttagaaa aacatcaaat tgttaaaggg gtggaattat
    96661 aatgcgagtt gatttgaatt gtgatttagg cgaagcattt ggaaattatt cctttggtgg
    96721 tgatcatcaa attattccgt taattacaag tgcgaatgtt gcttgtggtt ttcacgctgg
    96781 tgatgaaaat gtaatgaatg aaacggtaaa acttgccaaa gcacataatg ttgcagtagg
    96841 tgcacatcct ggtttacctg atttgaaagg ctttggcaga cgaaatatag atatctctaa
    96901 cgacgagatt tataatttga tgatttatca attaggtgca ttacaagggt tttgtcgcat
    96961 tcatcaactt aaaattaatc atgttaaacc gcatggtgca ttgtatcaga tgggtgcaaa
    97021 agacagagaa atagcaaacg ttatagcaca agctgtttat gactttgatc catcactagt
    97081 gttagtagga ttagcaaatt catatctaat ttcagaagca aagaatgtcg gattaattac
    97141 agcttctgaa gtgtttgctg atagacgata cgaagatgat gggcagctcg ttagtagaaa
    97201 agaaagtgat gctgtgatta ctgatactga cgaagcactt aagcaggttt taaagatggt
    97261 gaaggaaaat aaagttattt caaaaaacaa taaggaagta acgttacaag cagatacaat
    97321 ttgtgtgcat ggtgatggag aacatgcatt attatttgtt tcgaaaatta gagaaatttt
    97381 aatgaaagaa ggcattgata ttcaatcctt atagggggct aaaaaaatgg ggagaaattt
    97441 aaagcttaaa aaagaaagtg actttgaatt cacaaaaaat cataaaaggt tattattagg
    97501 ttctgtattt ttgatggcaa cttctgcaat tgggccagca tttttaacgc aaacagcagt
    97561 atttacatca caattttttg caagtttcgc atttgccata ttactgtcta tcatcattga
    97621 cattggtgca caaattaata tatggcgcat attagttgta actggtttaa gaggtcaaga
    97681 aatatcaaat aaagttgttc ctgggcttgg tactgttatc tcaatattga ttgcatttgg
    97741 tggtctagct tttaatattg gtaatattgc tggtgccggt ttaggtttaa atgcaatttt
    97801 tggattagat gtaaaatggg gcgcagctat tactgcaatc tttgcaatat taatctttgt
    97861 aagtaaaagt ggccaaaaaa ttatggacgt tgtttcaatg attcttggta ttgtgatgat
    97921 tttagttgtg gcatatgtga tgtttgtttc taatccacct tatggtgatg cttttgtgca
    97981 tacatttgcg ccagaacatc caatgaaatt agtcttgccc atcattacgt tagttggtgg
    98041 aactgtaggt ggttatatta cctttgcagg tgcacatcgt atattagact ctggcattaa
    98101 aggtaagcaa tatttaccat ttgtaaatca atcagcaatt gctggtattt taactacagg
    98161 tattatgaga acgttactat tcctagcggt attaggagtt gttgtaacag gtgtgacact
    98221 aagttctgaa aatccaccag cgtcagtttt tgaacacgca attggaccaa ttggaaagaa
    98281 tatttttggt attgtgttat ttgctgcagc tatgtcatca gtaattggct cagcatacac
    98341 aagcgcaaca tttttaaaaa cacttcataa atcacttaac gaaagaagta atttaattgt
    98401 gattgtgttt atcgttattt caacaatgat tttcttattt attggaaaac caatcagcct
    98461 tttaattata gcaggcgcga taaatggatg gattttacct attacgttag gtgcaatttt
    98521 gattgcaagt aaaaagaaat caattgttgg tgattataaa cacccaaatt ggatgttcat
    98581 ctttggtatc gttgcagtac ttgttacaat attgacaggt atattctcat tcaaagaagt
    98641 acttcagtta ttttaaaaga catttcgact aatagcatca ctgtaaatgt tgttagtatt
    98701 aggcaagata tattttgatt tccggtgatt catttataaa gcataattag atatatttta
    98761 agggagagtg gtgcatgaca aatgtactgc tctttttgtt gtgatgaaaa atctttttct
    98821 attgattgag aaaatagtta tttatatagt ttttaaagaa aaaaagtgat aatatttagc
    98881 taatctaatg aaaatggatt tattggacaa aaaatacatt ttaaatgagt agaggaggct
    98941 gcaaatgggt tacagaactt taaaaagtat ttttcatgaa cacaatgaaa gtaaaatgaa
    99001 ggaagagtat actaaaagat ttaattcttt agcttctttc aatactaata ttaatatcat
    99061 acctatggaa aatggaaaaa aagttaatga tttggaatat cctctattct ttatggtgac
    99121 taaaaatcta tcaaaaaaac aagaattaat atcaattaat agtagaaaaa ttgatagagc
    99181 acttaattct ttaccatatg cagctagaga acaatatttt aatgatttat taatcgatga
    99241 attacaaagt actaatgaaa ttgaaaatgt atttagtact aaacaagaga ttgcacatgc
    99301 gttaaataac caagcatcag aatttcttaa gttcagaggc ctcgtggatc aatataaaga
    99361 gatagaactt aataaaaaaa ttaaagttga taatgtaaga gacattagag cgatttatga
    99421 taaattagtt tcaaatgaaa ttaacgaaca agataagtta gatggagagc tatttcgtaa
    99481 aaattttgtc ggtgtgcatg atgggtcaac gaataaatat atacatgttg ggttacaacc
    99541 tgaaaccaaa attgttgaat atataggtga aatgctaaca tttttaaaat attttgatgc
    99601 gcctcagccg ttcaaaatca tggctagtca ttatctgttt gaatatatac atccttttta
    99661 tgatggcaat ggtagagttg gaagatttat aattgccaag ctcttgagtg attattatga
    99721 taattatact gctttgacat tttcatatgt tataaataga aataaatcga aatattacaa
    99781 ggcgtttatg actgcttcaa atcatttgaa ttgtggtgat ttgacggaat ttattgacac
    99841 aatgcttgag ctattgatag caggacaaga aagaatactt gatgagttaa taccaaaaat
    99901 ggatgcgact gaaaaattaa cgctttattt aactagtcat tataaacaga tagattatga
    99961 atttttgtat ctcctttcaa tggataaatt gtttggaaat aaaagaaata gattaacatt
   100021 aattgattta gaaaacatat tgggagtagg aagagtaaaa attaataata caattaaaaa
   100081 atatgataac tacttagtta aaattaaaag tagaccaaca atttatgaga taagtgatga
   100141 atttctaaat tcgattataa aataaatata atatgtgatt cagctatact tatagtattt
   100201 gtaagatcgc gtaattgctt cattgaaaaa tatatttgtt gagagtggtg catgacaaat
   100261 gtactgctct ttttgttgtg tatcagtatt gtgatgtttt aatgcgaata ttatatgaat
   100321 cattatgaaa tttaataaaa ataaaagaaa tgattatcat tttttctgat atactgttaa
   100381 acggtttgga atttttatgt ttacactgta ttggttgata taactcaact aataattgcg
   100441 aacagggtat ttcaaattgg aaagtattat gaacgtgata cataatcaaa attgtaggct
   100501 caagggagtg ggacagaaat gataaagagc cactaatgat ttattatgta gtggttctta
   100561 cacattagcc acagctaatg tgtacttaaa aataggaata catgagtaaa actcatgtat
   100621 aagaaatact aatttctata gaaaaagtat ttctttatcg tcgtcccacc caacttgcac
   100681 attattgtaa gctgactttc cgccagcttc tatgttgggg ccccgcccca acttgcattg
   100741 cctgtagaat ttcttttcga aattctctgt gttggggccc ctgactagaa ttgaaaaaag
   100801 cttgttacaa gtgcattttc gttcagtcaa ctactgccaa tataacttcg tagagcatag
   100861 aacattgatt tatgtcccag cctgtttatc atttatgtct cgctctcaaa tgtaaattaa
   100921 taattgtttt gggggagttt gaagttaaat atttaacagg atttatttta atattattgt
   100981 tagaaggaat ttttacaaat tcagcgagtg caatcgaata ttcagactta catcataaaa
   101041 gtaagtttga ttcaaagcgt ctaagtaatg ctaagatgtc attcatcaat ccaactcagc
   101101 ttgaaaataa aaacacaaac gatagactgt tgaagcatga tttgttattt catgacatgt
   101161 tcgtaaatgt tgcttcgaaa aaggatttta aagttgaatt cgaaaatgag gcactttcaa
   101221 agaaatttat aaataagaat atcgatatat atgctggaag ctatagctat gaatgtcatg
   101281 ggggagcaac caataaaacg caatgtagtt atggtggtgt tactttaagt gacaataata
   101341 aataagatga ttataagaat ataccttcta atttatggat tgacggacat caaacagaaa
   101401 tagaactaac tgcagtaaaa acgaaaaaag aaaattgtta ccattcaaga attagatgtt
   101461 caattaagaa attatttgaa tgagaagtat aagttgtacg aacaaggtgg cgacattgtt
   101521 aaagggtatg ttaaatatca taatgatgat gaacaaaatg tagaatatga tttttataat
   101581 ttaa
//
LOCUS       DAPDIM010000002        99083 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000002 DAPDIM010000000
VERSION     DAPDIM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 99083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99083
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.002"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..1160)
                     /gene="essB"
                     /locus_tag="RFE25_000099"
     CDS             complement(<1..1160)
                     /gene="essB"
                     /locus_tag="RFE25_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HDU2815208.1"
                     /translation="MVKNHNPKNEMQDMLTPLDAEEAAKTKLRLDMREIPKSSIKPEH
                     FHLMYLLEQHSPYFIDAELTELRDSFQIHYDINDNHTPFDNIKSFTKNEKLRYLLNIK
                     NLEEVNRTRYTFVLAPDELFFTRDGLPIAKTRGLQNVVDPLPVSEAEFLTRYKALVIC
                     AFNEKQSFDALVEGNLELHKGTPFETKVIEAATLDLLTAFLDEQYQKQEQDYSQNYAY
                     VRKVGHTVFKWVAIGMTTLSVLLIAFLAFLYFSVMKHNERIEKGYQAFVKDDYTQVLN
                     TYDDLDGKKLDKEALYIYAKSYIQTNKQGLEKDKKENLLNNVTPNSNKDYLLYWMELG
                     QGHLDEAINIATYLDDNDITKLALINKLNEIKNNGDLSNDKRSEETKKYNDK"
     gene            complement(1173..1415)
                     /gene="esaB"
                     /locus_tag="RFE25_000100"
     CDS             complement(1173..1415)
                     /gene="esaB"
                     /locus_tag="RFE25_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EsaB"
                     /protein_id="HDU2815209.1"
                     /translation="MNQHVKVTFDFTNYNYGTYDLAVPAYLPIKNLIALVLDSLDISI
                     FDVNTQIKVMTKGQLLVENDRLIDYQIADGDILKLL"
     gene            complement(1387..1845)
                     /gene="essA"
                     /locus_tag="RFE25_000101"
     CDS             complement(1387..1845)
                     /gene="essA"
                     /locus_tag="RFE25_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssA"
                     /protein_id="HDU2815210.1"
                     /translation="MLMNSVIALTFLTASSNNGGLNIDVQQEEEKRINNDLNQYDTTL
                     FNKDSKEVNDAIAKQKKERQQQIKNDMFQNQASHSTRLNETKKVLFSKSNLEKTSESD
                     KSPYIQNKQEKKIFPYILMSVGAFLTLGFVIFSIHKGRRTKNESARKSNI"
     gene            complement(1845..4874)
                     /gene="esaA"
                     /locus_tag="RFE25_000102"
     CDS             complement(1845..4874)
                     /gene="esaA"
                     /locus_tag="RFE25_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EsaA"
                     /protein_id="HDU2815211.1"
                     /translation="MKKKNWIYALIVTLIIIIAIVSMIFFVQTKYGDQSEKGSQSVSN
                     KNNKIHIAIVNEDQPTTYNGKKVELGQAFIKRLANEKNYKFETVTRNVAESGLKNGGY
                     QVMIVIPENFSKLAMQLDAKTPSKISLQYKTAVGQKEEVAKNTEKVVSNVLNDFNKNL
                     VEIYLTSIIDNLHNAQKNVGAIMTREHGVNSKFSNYLLNPINDFPELFTDTLVNSISA
                     NKDITKWFQTYNKSLLSANSDTFRVNTDYNVSTLIEKQNSLFDEHNTAMDKMLQDYKS
                     QKDSVELDNYINALKQMDSQIDQQSSMQDTGKEEYKQTVKENLDKLREIIQSQESPFS
                     KGMIEDYRKQLTESLQDELANNKDLQDALNSIKMNNAQFAENLEKQLHDDIVKEPDTD
                     TTFIYNMSKQDFIAAGLNEGEANKYEAIVKEAKRYKNEYNLKKPLAEHINLTDYDNQV
                     AQDTSSLINDGVKVQRTETIKSNDINQLTVATDPHFNFEGDIKINGKKYDIKDQSVQL
                     DTSNKEYKVEVNGVAKLKKDAEKDFLKDKTMHLQLLFGQANRQDEPNDKKATSVVDVT
                     LNHNLDGRLSKDALSQQLSALSRFDAHYKMYTDTKGREDKPFDNKRLIDMMVDQVIND
                     MESFKDDKVAVLHQIDSMEENSDQLIDDILNNKKNTTKNKEDISKLIDQLENVKKTFA
                     EEPQEPKIDKGKNDEFNTMSSNLDKEISRISEKSTQLLSDTQESKTIADSVSGQLNQL
                     DNNVNKLHATGRALGVRANDLNRQMAKNDKDNELFAKEFKKVLQNSKDGDRQNQALKA
                     FMSNPVQKKNLENVLANNGNTEVISPTLFVLLMYLLSMITAYIFYSYERAKGQMNFIK
                     DDYSSKNHLWNNVITSGVIGTTGLVEGLIVGLIAMNKFHVLAGYRAKFILMVILTMMV
                     FVLINTYLLRQVKSIGMFLMIAALGLYFVAMNNLKAAGQGVTNKISPLSYIDNMFFNY
                     LNAEHPIGLALVILTVLVIIGFVLNMFIKHFKKERLI"
     gene            complement(4957..5250)
                     /gene="esxA"
                     /locus_tag="RFE25_000103"
     CDS             complement(4957..5250)
                     /gene="esxA"
                     /locus_tag="RFE25_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WXG100 family type VII secretion effector EsxA"
                     /protein_id="HDU2815212.1"
                     /translation="MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWE
                     GQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ"
     gene            5498..6391
                     /locus_tag="RFE25_000104"
     CDS             5498..6391
                     /locus_tag="RFE25_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2815213.1"
                     /translation="MKKTILLTMTTLTLFSMSPNSAQAYTNDSKTLEEAKRAHPNAQF
                     KVNKDTGAYTYTYDKNNTPNNNHQNQSRTNDNHQHANQRDFNNNQYHSSLSGQYTHIN
                     DAIDSHTPPQTSPSNPLTPAIPNVEDNDDELNNAFSKDNKGLITGIDLDELYDELQIA
                     EFNDKAKTADGKPLALGNGKIIDQPLITSKNNLYTAGQCTWYVFDKRAKDGHTISTFW
                     GDAKNWAGQASSNGFKVDRHPTRGSILQTVNGPFGHVAYVEKVNIDGSILISEMNWIG
                     EYIVSSRTISASEVSSYNYIH"
     gene            6722..8245
                     /locus_tag="RFE25_000105"
     CDS             6722..8245
                     /locus_tag="RFE25_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815214.1"
                     /translation="MSKKLKIIIPIIIVLLLIGGIAWGVYAFFANTPKNTYLKSEQQT
                     AKMYKDYFNDRFENEVKFQEKMKDNSFLSSLELSADASDEIVKGLGIPKSVVNASKIK
                     MSYGHDPKKEKSMINLEPTIADSALGKFQLAADKDKHYFESPLFKGKYSVNNSDLLST
                     YSKLTGEDEETAKENGITNQQLNLNTLFSNAQAQQSDYSKIAEKYSELIVDKLDDDNF
                     DKGKKEEIKVNGEKYKVRPVTLTLSRADTKKITLAVLEEAKKDKDLKKLMEEQGATKD
                     YDKDIKKAIDDVKETKKDEFAKIQSKIYTEKHTIVKREITITDKENNKTKIKGTNTLE
                     DDKLKLDYALDFDQDKYTYAEAKYTIKGVSSKEKDNKYSDKYEFGKKTEYDESKIKLD
                     NQEKVDGTKRQDKGKITVALDKYSDENEFTFENNIDSDVKNNTQKSTLNIGIKYAEEP
                     INFILKSSTKLKADIDFDDSGAKDFNSLSSKDREKLEKEIEKNGGKMFESILKKASK"
     gene            8313..9479
                     /locus_tag="RFE25_000106"
     CDS             8313..9479
                     /locus_tag="RFE25_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815215.1"
                     /translation="MKTIHLFRIYHSFLLKKWYLIIYLLFILAALLITLTTIQHVTED
                     DNHFNIGVVDKDQSSETKLILNSIGKGSNLGKNVSIKAYDDKQAHTLLKKHKLQGYFV
                     FDKGMTKAFYKQGELPISVYTYDQQSMKSVVLSQLTDSVYQRLMRSMGGILAFQDLAP
                     KASHSDSINVMTDLLITGLNRSGAFNLEPIHLYDTGSYYAITGFLATVFIFALSLFTV
                     LKMNQDTVLKARLKMFHFSKERLLIIRALITWFYTMLWSIVGVVWIVFSIPNTFELYN
                     WPTLAIHLSYYVTFLILWLLLIELLTTGLLNSISKVILAIVILVLSGLTIPTIFLQHI
                     ANGVFNIQPFAVVTNQLLEIILNNYILELHPSFYLSFIALLIINLAVLVWRYRQ"
     gene            9476..10396
                     /locus_tag="RFE25_000107"
     CDS             9476..10396
                     /locus_tag="RFE25_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815216.1"
                     /translation="MKPYIQLVLFKQWLQYILLVTTIVIALVLIGIGYRVAHDNFKIP
                     ITIQDLDQTTASKSFVNKIKQSDYVTIKKVDEDESYIEDDVTKKEAILSMQIPKGFSQ
                     KLKENRLKETIQLYGRDDFIGGIAIEIVSSSLYEQQIPNIIYEHLEDMKQHQSIDAIN
                     KSYHKHTPESKIKFVSLTKQAQHSISISLIFAVILFVSAVQVVLHYRLNQQAALQRLS
                     QYHLSRFKLYSTYVMTHTILLLLVLLAVSLYLSQPLSLIFYLKSLLLILIYEIGIVFI
                     LFHIQTISHRLFMTFIYALAMGIVYLIIFM"
     gene            10410..11069
                     /locus_tag="RFE25_000108"
     CDS             10410..11069
                     /locus_tag="RFE25_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815217.1"
                     /translation="MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLL
                     RMIAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENIKFFKSLCKN
                     PINDTTINEYLQQLNFDDTSAKVSTLSGGNKRKINILVGLLGQPRILILDEPTVGIDL
                     KSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWAYTY
                     Y"
     gene            complement(11121..12071)
                     /gene="lytM"
                     /locus_tag="RFE25_000109"
     CDS             complement(11121..12071)
                     /gene="lytM"
                     /locus_tag="RFE25_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-glycine endopeptidase LytM"
                     /protein_id="HDU2815218.1"
                     /translation="MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTLMSTQSQD
                     VSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANAN
                     GSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGN
                     GKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMP
                     ENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGD
                     QIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR"
     gene            complement(12397..13389)
                     /locus_tag="RFE25_000110"
     CDS             complement(12397..13389)
                     /locus_tag="RFE25_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDU2815219.1"
                     /translation="MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTG
                     TTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNE
                     IVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGE
                     VVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATAKLLEGVTIEPLGNEAGTFGLP
                     GGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMY
                     QTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ"
     gene            13623..14999
                     /locus_tag="RFE25_000111"
     CDS             13623..14999
                     /locus_tag="RFE25_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2815220.1"
                     /translation="MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTS
                     PAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALL
                     IIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIAT
                     NFGWQMNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLT
                     QGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVL
                     NSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLII
                     GPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVG
                     LATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYM
                     IIPKTVKS"
     gene            complement(15127..15519)
                     /locus_tag="RFE25_000112"
     CDS             complement(15127..15519)
                     /locus_tag="RFE25_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815221.1"
                     /translation="MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFG
                     DTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLM
                     LTDFQKENYNKYIQGQKQRVIFENGHFV"
     gene            complement(15569..15748)
                     /locus_tag="RFE25_000113"
     CDS             complement(15569..15748)
                     /locus_tag="RFE25_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HDU2815222.1"
                     /translation="MRRENILLRLIPFNDYDNKNFKMFIVMKNTKVIILKNKIFVFEQ
                     SIKKHNEMMYIELCD"
     gene            15899..16897
                     /locus_tag="RFE25_000114"
     CDS             15899..16897
                     /locus_tag="RFE25_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDU2815223.1"
                     /translation="MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSE
                     RLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTAT
                     DLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTN
                     EYQGGQLAAQHLIELGHNHMIIVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTEL
                     SKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAA
                     YVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN"
     gene            17129..18010
                     /gene="rbsU"
                     /locus_tag="RFE25_000115"
     CDS             17129..18010
                     /gene="rbsU"
                     /locus_tag="RFE25_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose transporter RbsU"
                     /protein_id="HDU2815224.1"
                     /translation="MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIF
                     AIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELIGSSRAMPVTTAFQLLG
                     ASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLI
                     GEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKSENPFRNKITWLQII
                     SGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITI
                     IGLVLILVAASVTVFIK"
     gene            18025..18429
                     /gene="rbsD"
                     /locus_tag="RFE25_000116"
     CDS             18025..18429
                     /gene="rbsD"
                     /locus_tag="RFE25_000116"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDU2815225.1"
                     /translation="MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAV
                     TKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEM
                     KSNLAHPLNKGNIRTGETTPYSNIALESNVTF"
     gene            18457..19371
                     /gene="rbsK"
                     /locus_tag="RFE25_000117"
     CDS             18457..19371
                     /gene="rbsK"
                     /locus_tag="RFE25_000117"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDU2815226.1"
                     /translation="MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGA
                     NQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTTEAKTGQAFITVN
                     AEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGV
                     TTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKT
                     VLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAID
                     FGNKASSLTVQKHGAQASIPLLEEVNQV"
     gene            complement(19469..19603)
                     /locus_tag="RFE25_000118"
     CDS             complement(19469..19603)
                     /locus_tag="RFE25_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815227.1"
                     /translation="MIIIIINIAYLYAIIWKLKRLQKIVTSFITKHESTSIGLVENYF
                     "
     gene            19622..20383
                     /locus_tag="RFE25_000119"
     CDS             19622..20383
                     /locus_tag="RFE25_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006191654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDU2815228.1"
                     /translation="MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEV
                     ACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFD
                     DNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSL
                     SAAINVNVSPQTKLGWLDLYHQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTIKIIKN
                     ALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKED"
     gene            complement(20870..22306)
                     /locus_tag="RFE25_000120"
     CDS             complement(20870..22306)
                     /locus_tag="RFE25_000120"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDU2815229.1"
                     /translation="MTKLPQNFMWGGALAANQFEGGYEKGGKGLSVIDVMTSGAHGKA
                     RQITESIDLNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVP
                     NEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVV
                     FERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLAS
                     ALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYP
                     SYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGG
                     LNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIH
                     DDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDN
                     DGHGTMERLKKDSFYWYQQVIASNGDKL"
     gene            complement(22322..23113)
                     /locus_tag="RFE25_000121"
     CDS             complement(22322..23113)
                     /locus_tag="RFE25_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDU2815230.1"
                     /translation="MSNKYKEQAQDILTAVGGVENIVDATYDTKCITIHMQHTIPSTA
                     NEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKNANVEESENTDNINSQDTS
                     YTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGL
                     ISMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDHVEAGQTLLQFDQ
                     QYIQQQGYNADVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN"
     gene            23262..23966
                     /locus_tag="RFE25_000122"
     CDS             23262..23966
                     /locus_tag="RFE25_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDU2815231.1"
                     /translation="MLKYEHIAKQLNAFIHQSNFKPGDKLPNVTQLKERYQVSKSTII
                     KALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEM
                     ATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIF
                     DYLESNMKLRIGFSDIFFNVDKLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSD
                     IVFHYRHAQFYIPSKK"
     gene            complement(24074..24775)
                     /gene="lrgB"
                     /locus_tag="RFE25_000123"
     CDS             complement(24074..24775)
                     /gene="lrgB"
                     /locus_tag="RFE25_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiholin-like protein LrgB"
                     /protein_id="HDU2815232.1"
                     /translation="MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSM
                     VFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIG
                     IGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILN
                     GVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVG
                     VVVVAVVPVFVAIFF"
     gene            complement(24768..25211)
                     /gene="lrgA"
                     /locus_tag="RFE25_000124"
     CDS             complement(24768..25211)
                     /gene="lrgA"
                     /locus_tag="RFE25_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiholin-like murein hydrolase modulator LrgA"
                     /protein_id="HDU2815233.1"
                     /translation="MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASV
                     IGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIG
                     LIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD"
     gene            complement(25324..26064)
                     /locus_tag="RFE25_000125"
     CDS             complement(25324..26064)
                     /locus_tag="RFE25_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor LytR"
                     /protein_id="HDU2815234.1"
                     /translation="MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLI
                     NQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKP
                     FGQKRIEQAVNKVRATKAKDDNNASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGI
                     GTHNGITTIHTTNHKYETTEPLNRYEKRLNPTYFIRIHRSYIINTKHIKEVQQWFNYT
                     YMVILTNGVKMQVGRSFMKDFKASIGLL"
     gene            complement(26067..27821)
                     /locus_tag="RFE25_000126"
     CDS             complement(26067..27821)
                     /locus_tag="RFE25_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDU2815235.1"
                     /translation="MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQL
                     CIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVG
                     LFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIV
                     MEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAV
                     QTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSD
                     HHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTL
                     KMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFF
                     FNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQ
                     ARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETAT
                     HVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFEST
                     SSGTTFWCVLPYERQEEE"
     gene            complement(28066..28740)
                     /gene="scdA"
                     /locus_tag="RFE25_000127"
     CDS             complement(28066..28740)
                     /gene="scdA"
                     /locus_tag="RFE25_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair di-iron protein ScdA"
                     /protein_id="HDU2815236.1"
                     /translation="MINKNDIVADIVIDYPKAADIFRSVGIDFCCGGQVSIEAASLEK
                     KNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVT
                     KLSKVHGPNHPYLVELKETYDTFKSGMLEHMQKEDDVDFPKLIKYEQGEVVNDINTVI
                     DDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHV
                     LFKKVS"
     gene            complement(28884..30605)
                     /gene="tarS"
                     /locus_tag="RFE25_000128"
     CDS             complement(28884..30605)
                     /gene="tarS"
                     /locus_tag="RFE25_000128"
                     /EC_number="2.4.1.355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly(ribitol-phosphate)
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDU2815237.1"
                     /translation="MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCST
                     DQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETL
                     KDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRT
                     ALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVS
                     PEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEEQPQWI
                     NALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGK
                     LNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHS
                     RNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQ
                     RNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISMKLKGKNKII
                     LTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTA
                     HMTYSLK"
     gene            complement(30638..32326)
                     /locus_tag="RFE25_000129"
     CDS             complement(30638..32326)
                     /locus_tag="RFE25_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDU2815238.1"
                     /translation="MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRT
                     MKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQN
                     LKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDV
                     VVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSD
                     SRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIF
                     VDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYV
                     SSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVIL
                     FAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYF
                     VDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYE
                     SFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS"
     gene            complement(32348..33373)
                     /locus_tag="RFE25_000130"
     CDS             complement(32348..33373)
                     /locus_tag="RFE25_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDU2815239.1"
                     /translation="MINQVYQLVAPRQFEVTYNNVDIYSDYVIVRPLYMSICAADQRY
                     YTGSRDENVLSQKLPMSLIHEGVGEVVFDSKGVFNKGTKVVMVPNTPTEKDDVIAENY
                     LKSSYFRSSGHDGFMQDFVLLNHDRAVPLPDDIDLSIISYTELVTVSLHAIRRFEKKS
                     ISNKNTFGIWGDGNLGYITAILLRKLYPESKIYVFGKTDYKLSHFSFVDDVFFINKIP
                     EGLTFDHAFECVGGRGSQSAINQMIDYISPEGSIALLGVSEFPVEVNTRLVLEKGLTL
                     IGSSRSGSKDFQDVVDLYIQYPDIVDKLALLKGQEYEIATINDLTEAFEADLSTSWGK
                     TVLKWIM"
     gene            complement(33366..34082)
                     /locus_tag="RFE25_000131"
     CDS             complement(33366..34082)
                     /locus_tag="RFE25_000131"
                     /EC_number="2.7.7.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribitol-5-phosphate cytidylyltransferase"
                     /protein_id="HDU2815240.1"
                     /translation="MKYAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILIN
                     DFEKIIIATPQQWMTHTKDTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGIN
                     DDDVIVTHDAVRPFLTHRIIKENIQAALEYGAVDTVIDAIDTIVTSKDNQTIDAIPVR
                     NEMYQGQTPQSFNINLLKESYAQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKV
                     TTPYDLKVANAIIRGGIADD"
     gene            complement(34358..35527)
                     /locus_tag="RFE25_000132"
     CDS             complement(34358..35527)
                     /locus_tag="RFE25_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDU2815241.1"
                     /translation="MIKNTIKKLIEHSIYTTFKLLSKLPNKNLIYFESFHGKQYSDNP
                     KALYEYLTEHSDAQLIWGVKKGYEHIFQQYNVPYVTKFSMKWFLAMPRAKAWMINTRT
                     PDWLYKSPRTTYLQTWHGTPLKKIGLDISNVKMLGTNTQNYQDGFKKESQRWDYLVSP
                     NPYSTSIFQHAFHVSRDKILETGYPRNDKLSHKRNDTEYINGIKTRLNIPLDKKVIMY
                     APTWRDDEAIREGSYQFNVNFDIEALRQALDDDYVILLRMHYLVVTRIDEHDDFVKDV
                     SDYEDISDLYLISDALVTDYSSVMFDFGVLKRPQIFYAYDLDKYGDELRGFYMDYKKE
                     LPGPIVENQTALIDALKQIDETANEYIEARTVFYQKFCSLEDGQASQRICQTIFK"
     gene            complement(35955..37649)
                     /locus_tag="RFE25_000133"
     CDS             complement(35955..37649)
                     /locus_tag="RFE25_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDU2815242.1"
                     /translation="MTKTKQAIHIDNIYWERVQLYIEGHSEGVDLTSGQFVLRNLTET
                     KTLEANEMKIDGNTFICRFNVAILDDGYYLPMDKYLFVYHDQLEYIGQLNPNIIDQAY
                     AALNEEQIEEYNELTTQNGKVNYLLAYDAKVFRKGGVSQHTVYTITPEIASDVNEFVF
                     DIEITLPQEKSGVIATSAHWLHKQGHKASFESRSFLFKAIFNITKLLHIKRSKTILFT
                     SDSRPNLSGNFKYVYDELLRQKVDFDYDIKTVFKANITDRRKWRDKFRLPYLLGKADY
                     IFVDDFHPLIYTVRFRPSQEIIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKA
                     YVSSETDIPFYAEAFGIREENVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKV
                     ILFAPTFRGNGHGTAHYPFFKIDFERLARYCEKHNAVVLFKMHPFVKNRLNISREHRQ
                     YFIDVSDHREVNDILFVTDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEP
                     YESFVPGKIVQSFDALMDALDTEDYEVEKVVPFLDKHFKYQDGRSSERLVKDLFRR"
     gene            complement(37671..38696)
                     /locus_tag="RFE25_000134"
     CDS             complement(37671..38696)
                     /locus_tag="RFE25_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDU2815243.1"
                     /translation="MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRY
                     YTGRRDENVLRKKLPMSLVHEAVGEVVFDSKGVFEKGTKVVMVPNTPTEQHHIIAENY
                     LASSYFRSSGYDGFMQDYVVMAHDRIVPLPNDIDLSTISYTELVSVSYHAIQRFERKS
                     IPLKNSFGIWGDGNLGYITAILLRKLYPEAKIYVFGKTDYKLSHFSFVDDIFTVNQIP
                     DDLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTL
                     IGSSRSGSKDFEQVVDLYRKYPDIVEKLALLKGHEINVCTMQDIVQAFEMDLSTSWGK
                     TVLKWTI"
     gene            complement(38689..39405)
                     /locus_tag="RFE25_000135"
     CDS             complement(38689..39405)
                     /locus_tag="RFE25_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDU2815244.1"
                     /translation="MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVS
                     EFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNVNGIN
                     NDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVR
                     NEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKV
                     TTPYDLKVANAIIQGDIADD"
     gene            complement(39933..40976)
                     /locus_tag="RFE25_000136"
     CDS             complement(39933..40976)
                     /locus_tag="RFE25_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDU2815245.1"
                     /translation="MKALKLYGVEDLRYEDNEKPVIESANDVIVKVRATGICGSDTSR
                     YKKMGPYIKGMPFGHEFSGVVDAIGSDVTHVNVGDKVTGCPAIPCYQCEYCLKGEYAR
                     CEKLFVIGSYEPGSFAEYVKLPAQNVLKVPDNVDYIEAAMVEPSAVVAHGFYKSNIQP
                     GMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIATSLGAHQTINSKEENLE
                     KFIENHYANQIDLAIESSGAKVTIGQILTLPKKGGEVVLLGIPYDDIEIDRVHFEKIL
                     RNELTVCGSWNCLSSNFPGKEWTATLHYMKTKDINVKPIISHFLPLEKGPETFDKLVN
                     KKERFDKVMFTIY"
     gene            complement(41000..41146)
                     /locus_tag="RFE25_000137"
     CDS             complement(41000..41146)
                     /locus_tag="RFE25_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815246.1"
                     /translation="MVESMLTFMLGPLRQITDFYMEHLLVSNSIVIAGYFATGIFKKK
                     KVVN"
     gene            complement(41148..42203)
                     /locus_tag="RFE25_000138"
     CDS             complement(41148..42203)
                     /locus_tag="RFE25_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDU2815247.1"
                     /translation="MKALVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIH
                     TYEGHYKVNFPVTLGHEFSGEIVEVGADVKDFKVGDRVTSETTFYVCNECEYCKSKDY
                     NLCNHRKGIGTQVDGAFTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQV
                     NSGDVAVVMGPGPIGLLVAQVLKSKGATVVVTGLDNDKVRLDKAEALHMDYVVNLQQT
                     DLKTYINGITDGYGADVVVECSGAVPAARQGLDIIRKKGFYSQIGIFKDAEIPFDMEK
                     VIQKEITVVGSRSQKPADWEPSLQLMADGLVNAEALVTKIYDISKWDEAYQHLKSGEG
                     IKALLKPLDLDENEGEN"
     gene            complement(42221..43480)
                     /locus_tag="RFE25_000139"
     CDS             complement(42221..43480)
                     /locus_tag="RFE25_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDU2815248.1"
                     /translation="MSYFTDFVRGFLDLGATVILPVVIFLLGLFFRQKIGAAFRSGLT
                     IGVAFVGIFLVIDLLVKNLGPAAQAMVKNLGVSLNVIDVGWPATSSIAWASSVAAFII
                     PLGIIVNVVLLVTKVTKTMNVDIWNFWHYTFTAAMVYAVSGSIWQALLAAVIFQVICL
                     KVADWTAPMMSEFFDLPGVSIATGSTISYAPGIYLVKLLQKVPGLNKLDADPETIQKR
                     FGAFGESIFVGLILGLGIGVLAGYKPGDIINLGMSMAAVMVLMPRMVKILMEGLMPVS
                     ESARTWLNKRFGEREIYIGLDAAVALGHPAVISTALILVPITVLLAVILPGNQVLPFG
                     DLATIPFVVAFIVGAARGNIIHSVIVGTIMIAISLYIATDVAPIFTDMAKVTNVQMPK
                     GSSEISSIDQGGIIVNYLIFKLFSLFN"
     gene            complement(43707..43985)
                     /locus_tag="RFE25_000140"
     CDS             complement(43707..43985)
                     /locus_tag="RFE25_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDU2815249.1"
                     /translation="MKQVLVACGAGIATSTVVNNAIEEMAKEHNIKVDIKQIKITEVG
                     PYEDTADLLVTTAMTKKEYKFPVINARNFLTGIGIEETKQQILTELQK"
     gene            complement(44008..44475)
                     /locus_tag="RFE25_000141"
     CDS             complement(44008..44475)
                     /locus_tag="RFE25_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDU2815250.1"
                     /translation="MGQQLVHKENIMLNLSATDKESVLSQMSDVLFQNGFVKSTFKDA
                     VIDREKEFATGLPTHLCSVAIPHTDVEHINHRTIGVAVLEKEVPFIEMGTLDQQTEVK
                     IVFMLAMDKVDDQLKLLQQLMQIFQSEEKLEQILRTKDETILATLINDYLEYN"
     gene            complement(44460..46556)
                     /locus_tag="RFE25_000142"
     CDS             complement(44460..46556)
                     /locus_tag="RFE25_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDU2815251.1"
                     /translation="MNGDNQQILREIVLNPTIHGKELESIFGLSRRQLGYRIQKINLW
                     LEQEGYPKLERTSQGNFIVSSEIMTLFKRDVSEQQMLNGNNVIFSIETRRYYLMLMLF
                     SKENAMSLNHFSIDLQVSKNTVIHDINHVKEQLEDHGLSLKYSRKHGYEIVGDEFEVR
                     RFFIKLIDQRLNHDITKSEVLKALNLTFEDIAYQKDKIKQVEQFLKSRFIDKSLSSLP
                     YVLCVIRRRIQSGHVMNPLNINYQYLRDTKEYQATEIMTQHEPDLPEAEKLYLTLHLL
                     STSVQWTDLQESDNISNLTMAIAQMIHHFEQITFINIEDKEKLSQQLLLHLTPAFYRI
                     KYNLTDRDELINPLQGNYQSLFHMVKQSCQSLTEYFGKSLPDNEIAYLTMLFGGSLRR
                     QDENFDGKIKAIIVCTQGTSVSQMMLYELRNLFPEIIFLDAISLRTFENYTLDYDIVF
                     SPMFVLTHKKLFITKVALSENEQRKLRKEVMKYINKESADIDKEINKLMALIERTTTV
                     NDITELRDGLEDFIANYNSISTINGSIVTQNKTLDLADLIPARHVKRMHHVENIDEAI
                     AKASDVLVANHFIDIKYIHEMQQVFDDSYMVIMQNIAIPHAYSEKHVHKTAMSMLILQ
                     EPIYMSDGTAIHIIVPIAAVDKVTHLRALLQLRDVAQDNDAIKRIIQSRKNSDVNEIL
                     KNYSNKEARENGWDSN"
     gene            complement(46687..46784)
                     /locus_tag="RFE25_000143"
                     /pseudo
     CDS             complement(46687..46784)
                     /locus_tag="RFE25_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498807.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(46894..47829)
                     /locus_tag="RFE25_000144"
     CDS             complement(46894..47829)
                     /locus_tag="RFE25_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDU2815252.1"
                     /translation="MKRKIIMDCDPGHDDAIALILAGAIDSPLEILAVTTVAGNQSVD
                     KNTTNALNVLDIMGRQDIAVAKGADRPLIKPAAFASEIHGESGLDGPKLPSTPSRQAV
                     AMPASDVIINKVMTSDTPVTIVATGPLTNVATALIREPRIAEHIESITLMGGGTFGNW
                     TPTAEFNIWVDAEAAKRVFESGITINVFGLDVTHQVLADNHVIERFESINNPVAQFVV
                     ELLQFFKKTYKTHFNMDGGPIHDACTILYLLQPELFTMVPVNIDIEHQSPLTYGTMAV
                     DLNHVTGKPANAYFATAVDVEEVWNLIDHKLRTYE"
     gene            48191..49720
                     /locus_tag="RFE25_000145"
     CDS             48191..49720
                     /locus_tag="RFE25_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDU2815253.1"
                     /translation="MKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAY
                     PILDITLLQNIFTLMSAAGSIVFQNLPVIFAIGVAIGLSRSDKGTAGLAALLGFLIMN
                     ATMNGLLTITGTLAKDQLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKVVL
                     PPYLGFFGGSRFVPIVTAFAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYG
                     FILRLLGPLGLHHIFYLPFWQTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGV
                     SRFMSGRFITMMFGLCGAALAIYHTAKPEHKKVVGGLMLSAALTSFLTGITEPLEFSF
                     LFVAPILYVIHAFFDGLAFMMADIFNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVI
                     PIGIVWFCLYYIVFRFLITKFNFKTPGREDKAAAQQVEATERAQTIVAGLGGKDNIEI
                     VDCCATRLRVTLNQNDKVDKVLLESTGAKGVIQQGTGVQVIYGPHVTVIKNEIEELLG
                     D"
     gene            complement(50040..50993)
                     /locus_tag="RFE25_000146"
     CDS             complement(50040..50993)
                     /locus_tag="RFE25_000146"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDU2815254.1"
                     /translation="MNKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKV
                     RGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKI
                     FKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLL
                     SEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQT
                     RDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYDEEDVYIGVPA
                     VINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEELK"
     gene            complement(51304..51411)
                     /locus_tag="RFE25_000147"
     CDS             complement(51304..51411)
                     /locus_tag="RFE25_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815255.1"
                     /translation="MSVCTPTIARIYLTNSKNIVVFLEKSKHDNKNVKV"
     gene            51566..52711
                     /locus_tag="RFE25_000148"
     CDS             51566..52711
                     /locus_tag="RFE25_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide dioxygenase"
                     /protein_id="HDU2815256.1"
                     /translation="MLTEQEKDIIKQTVPLLKEKGTEITSIFYPKMFKAHPELLNMFN
                     QTNQKRGMQSSALAQAVMAAAVNIDNLSVIKPVIMPVAYKHCALQVYAEHYPIVGENL
                     LKAIQDVTGLEEHDPVIQAWAKAYGVIADVFIQIEKEIYDQMMWIGFKPFKITNIKQE
                     SEDIKSFTVETEEYDFSEFTPGQYITVDVSSDKLPYRAKRHYSIVSGEKNHLTFGVKR
                     DVTTEHEGEVSTILHDEIKEGDMINLAAPVGGFVLENTTEPQLFLGSGIGVTPLVAMY
                     EAASAKGLDTQMVQVAENEQHLPFKDNFNSIASHYDNAKLYTHLKDKQGYIGTEELQA
                     FLANKPEIYICGGTKFLQSMIEALKSLNYDMDRVHYETFIPRLSVAV"
     gene            52737..52910
                     /locus_tag="RFE25_000149"
     CDS             52737..52910
                     /locus_tag="RFE25_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815257.1"
                     /translation="MKLNQRYVKVFALYFVSIVTANIIVKNNNLIKTLIQTIAGYTVF
                     AVGLKYLTKRKNK"
     gene            53067..53423
                     /locus_tag="RFE25_000150"
     CDS             53067..53423
                     /locus_tag="RFE25_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDU2815258.1"
                     /translation="MTVDIGRIYDNKDNTDAIRILVDRVWPRGISKRTANLDYWLKDI
                     APSTELRQWFQHDPKLFGAFKEKYEKELRDQDAQKDAFEKLKDIVNQHNHVLLLYAAK
                     DTKHNQAVVLQQLLNT"
     gene            53621..55096
                     /locus_tag="RFE25_000151"
     CDS             53621..55096
                     /locus_tag="RFE25_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDU2815259.1"
                     /translation="MKFKRLATIFSAVLVLSGCGSMHSSGKDLNISLPLKTKSIAPYE
                     TDVPVKIGAAESLFKTNDQGKIEKALVKSYHQPNDTTLDIELKDNIKFQNGQKLTAEK
                     VKSSLENSMKKSDLVKYSLPISSITAKGQKLTIKTNSAYPELVSELANPFMAIYYTDA
                     KSDVNQTPVGTGPYQIKDYKQSRKISLSNFKDYWQGKPKLDHITVTYQEDGNNRVRNL
                     ESQKDDLITDVPVNKVHDIENNQNLKVSKESGFRTSLLMYNHTNKKMTKSVREALDHI
                     IDRQGIADHIYQGYAKPATSPFNDKIPYIKEPKLTKQNIEQAKTLLAKDGYTKEHPLK
                     IKLITYDGRPELSKIAQVLQSDAKKANIEIDIKSVDDIEGYLKDRSAWDATMYSFGTI
                     PRGDTGYFFNQAYKKDGAINKGDYNNSNVDDLINQLNHTVDVKERHNISNDIIKLSSR
                     DVPNSYIAYNDQIVAANSKVKNYKVTPEGIYLIDYRTTIER"
     gene            complement(55410..56552)
                     /locus_tag="RFE25_000152"
     CDS             complement(55410..56552)
                     /locus_tag="RFE25_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDU2815260.1"
                     /translation="MSSASTQSTKTSDIHNESINKQMEAKAHETAQNADLKTEARSLF
                     DNATKSIGRLAGNDESLNLNLKDMFSEVFKPHTKNEADEIFIAGTAKTTPAICDISEE
                     WGKPWLFSRVFIAFTVTFIGLWVMAAIFNNTNAIPGLIFIGALTVPLSGLFFFYESNA
                     FKNISIFEVIIMFFIGGVFSLLSTMVLYRFVVFSDQFERFGSLTFFDAFLVGLVEETG
                     KALIIVYFVNKLKTNKILNGLLIGAAIGAGFAVFESAGYILNFALGENVPLLDIVFTR
                     AWTAIGGHLVWSAIVGAAIVIAKEQHGFEFKDIFDKRFLIFFLSAVGLHGIWDTSLTV
                     LGSDTLKIFILIVIVWILVFILMGAGLKQVNLLQKEFKEQQKKVDE"
     gene            56993..58570
                     /locus_tag="RFE25_000153"
     CDS             56993..58570
                     /locus_tag="RFE25_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDU2815261.1"
                     /translation="MEVTCLKQITWHDLQHIIKDGDVIGLPALAVANLPAEVLRAVLA
                     QHDTYHTPKDLTFILANDIHSLGAAPDLDDFIERRMIKRVIMSILTASSKTAQAMKNN
                     DIEAYFLPQGIIATHYRQSNQLLPGVITKIGLNTAVDPRYGGGKVNTRTTDDLVSLVT
                     INDETYLHYTFPSVDVALLRGTYADQQGNIYLTQEAYLSECYHVALNAKANHGKVIVQ
                     VKALVDDYQLKPNEVVIPGNLVDYVYVTEDEKNHRQVIQSHYLPALSGEERIDGIPEP
                     ALPFNSRKLILRRAAQFLTYGDTISIGYGINNELSNLLHEECVEHDVQPILDVGIFGG
                     FVGSREHFGMNYNADVRMPHDRAWDFIYNNGVSVAYLSFAEVDQYGNVNVSYFNDRLN
                     GCGGFIDITQSVNKIIFSGTFVAGSHVSCHNQRLNIETEGQNQKFVSDVSHIDFNAQY
                     SQLLEQEVYFVTDRAVFELTNQGLKLIEIAPGLDLHKDILNQMAFKPIIADHLKLIDT
                     SIYKEKWGQLKQSIHKV"
     gene            58596..60101
                     /locus_tag="RFE25_000154"
     CDS             58596..60101
                     /locus_tag="RFE25_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl--CoA ligase"
                     /protein_id="HDU2815262.1"
                     /translation="MNFDWIKTRSDFDDDKPAVIDHAKQTSWTYQQLNARADNMAHYL
                     TSQGVKKGDVIGIFAPNDIAILDLLFACFKTGAVFLPLNWRLNPKEIAAIVEDAQLKL
                     LFYAEKHLSSLTDIDQNLLHMDIDVAQYDEIVNPDYHQPFQATPVEPQDLAALIYTSG
                     TTGSPKGVMFSYESFVHNGTNLELTYKFNSNYITIVSTPMFHVLGFNDTVLPVLMSGG
                     TLILQRYFNGEELNDMIAQYHPTFIIMIPTMYYSTLRASNFNPENFRAMDYIIQGGSQ
                     PLPSIQAAFKQYGINIINGYGLTEAPLVLVNTPENSKRKPMSIGKAVMFVDARILDDN
                     GEEVPTGEIGELAIKAKNVTPGYWNKPAETAKAFHGRYLLTGDLAKMDDDGDIFIIDR
                     KKELIITGGENVLPSEVENALAEHPLVDRCVVVGYDHPKYGESIAAAIILREDEPHYA
                     EILDQHMRSRLAGYKVPRMYVPVTHMPLNSTQKPDKLAIRQMMNDKVSQTL"
     gene            60213..61424
                     /locus_tag="RFE25_000155"
     CDS             60213..61424
                     /locus_tag="RFE25_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDU2815263.1"
                     /translation="MTFEKETVLKTLFPEDVLSIAKGLTDGEVEFLQQVDSLLESKYR
                     ENINQHWIDATVPEDYFKDLGELNYFNNPLLYKDRPNAKMPSQLFQFFMSYLLARFDI
                     SLATLLGVHQGLGHNTFYFGGSKEQIAKYVPKLQSHELRTCFALTEPEHGSDVAGGLE
                     TVAERQGDTWVINGEKKWIGGAHVSDVIPVFAVNKKTGKPHCFVVRPEQDGVDIEVID
                     NKIALRIVPNALIKLTNVKVDEADRLQNITSFKDIAKILYSTRAGVAYMATGGMAGAL
                     RATLDYVTERKQFGKPISKYQLIQEKLAMMQGNLAQAMATCAQLANMQAHGEYDEVAT
                     STAKMMNALRLRETVAMGRGITGGNGILADDYDIARFFSDAEAIYTYEGTHEINALVI
                     GRALTGDSAFV"
     gene            61610..63871
                     /locus_tag="RFE25_000156"
     CDS             61610..63871
                     /locus_tag="RFE25_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
                     hydratase family protein"
                     /protein_id="HDU2815264.1"
                     /translation="MTINKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLI
                     AKKSYDKITDKKRPLLFDLNLVSHLTYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQ
                     QVLQHAKEDALFATNTSGIPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSH
                     TKESIILDVKNFAQNVLGKGVIVVNDVPGFVANRVGTQTMNDIMYRAEQHKLSIVDVD
                     ALTGQAIGRPKTGTYALSDLVGLDIAVSVIKGMQQVPEETPYFHDVKIVNTLFDNGAL
                     GRKTKQGFYKKDKETKARLVYDVEKQDYVPVSQPQLPILNEFNKDLVHNLDVIFNAQD
                     EAGLFLWETLRNNFYYSAINVPKATDDFRDIDRALVWGFNWKLGPFQLWDAMGYERVK
                     TRMEDELGDLPQWISDLDGGFYKQDETIEYATPVSHFVKDELWDKGDAKLSVTHDDQL
                     LLKLQSKNNVITDEFNDALVDAIDLLENDHYTSMVIYADGNNFSVGANLFLMKKAHED
                     GLVDDVVAQSIDKLHYSFNRLKYSLKPVVTAVQGRALGGGCELVLYSPIVVAASETYI
                     GLVEAGVGLLPSGGGLAEMADRILRTSHKFDDKQASMTKVLTNIAFAKVSTNAFEARR
                     YGYLRDTDTIIFNTAQRVEVALKRAKYEAETNYIPNPRHQYIALGEDFKALIQGQLDA
                     QRRGHFISDHDYHIALNIATILAGGDLPRNTFINQRYIQSLEKIGFIDLLKSKKSYER
                     IAHMLKTGKPLRN"
     gene            63901..65085
                     /locus_tag="RFE25_000157"
     CDS             63901..65085
                     /locus_tag="RFE25_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDU2815265.1"
                     /translation="MQEAYIVAYGRSAAAKAKQGALFHERPDDVAAKVLQGVLKRIDG
                     KFNKNMIEDVIVGTAFPEGLQGQNIARTIALRAGLSDTVPGQTVNRYCSSGLQTIAIA
                     ANQIMAGQGDILVAGGVELMSAVPMGGNEPTNNPTLQYDDIGASYPMGLTAENVASQF
                     DVSREDQDAYAVRSHQRAYDAQRDGRFKDEIIPIRVNSVEYTNAGPKVHTNIFDQDEF
                     IRPDTTMEALAKLRTVFKADGTVTAGTSAPLSDGAGFVVLMSGDKVKELGVTPIARFV
                     GYKAVGVDPKIMGIGPAYAIPEVLSLSNLSVEDIDLIELNEAFASQTIASIKEVGLDI
                     SRTNVNGGAIALGHPLGATGAMLTARLLNEMGRRPDSRYGMVTMCIGVGMGAAAIFEY
                     VR"
     gene            65383..65490
                     /locus_tag="RFE25_000158"
     CDS             65383..65490
                     /locus_tag="RFE25_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815266.1"
                     /translation="MCVRTRLVSSSSVRLSKAIIIAVIVVYHLDVRGLF"
     gene            complement(65672..67486)
                     /gene="coa"
                     /locus_tag="RFE25_000159"
     CDS             complement(65672..67486)
                     /gene="coa"
                     /locus_tag="RFE25_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylocoagulase"
                     /protein_id="HDU2815267.1"
                     /translation="MKKQIISLGALAVASSLFTWDNKADAIVTKDYSKESRVNEKSKK
                     GATVSDYYYWKIIDSLEAQFTGAIDLLEDYKYGDPIYKEAKDRLMTRVLGEDQYLLKK
                     KIDEYELYKKWYKSSNKNTNMLTFHKYNLYNLTMNEYNDIFNSLKDAVYQFNKEVKEI
                     EHKNVDLKQFDKDGEDKATKEVYDLVSEIDTLVVTYYADKDYGEHAKELRAKLDLILG
                     DTDNPHKITNERIKKEMIDDLNSIIDDFFMETKQNRPNSITKYDPTKHNFKEKSENKP
                     NFDKLVEETKKAVKEADESWKNKTVKKYEETVTKSPVVKEEKKVEEPQLPKVGNQQEV
                     KTTAGKAEETTQPVAQPLVKIPQETIYGETVKGPEYPTMENKTLQGEIVQGPDFLTME
                     QNRPSLSDNYTQPTTPNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQAT
                     ETTEASQYGPRPQFNKTPKYVKYRDAGTGIREYNDGTFGYEARPRFNKPSETNAYNVT
                     TNQDGTVSYGARPTQNKPSETNAYNVTTHANGQVSYGARPTYKKPSETNAYNVTTHAN
                     GQVSYGARPTQKKPSETNAYNVTTHADGTATYGPRVTK"
     gene            67676..68021
                     /locus_tag="RFE25_000160"
                     /pseudo
     CDS             67676..68021
                     /locus_tag="RFE25_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498788.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="complement inhibitor SCIN family protein"
     gene            complement(68185..69948)
                     /locus_tag="RFE25_000161"
     CDS             complement(68185..69948)
                     /locus_tag="RFE25_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HDU2815268.1"
                     /translation="MKRISKDIWAVFKLLYQNKGRFSINALLLQLIMIFISSTYLILL
                     FNMMLKVAGQSQLTINNWMEIISHPASVILLIIFILSVAFLIYVEFSLLVYMVYAGFD
                     RQIITFKSIFKNAFVNVRKLIGVPVIFFVIYLMLMIPIANLGLSSVLTKNIYIPKFLT
                     EELMKTTKGIIIYGTFMIAVFILNFKLIFTLPLTILNRQSLFKNMRLSWQITKRNKFR
                     LVIEIVILELIIGAILTLIISGATYLAICVDEEGDKFLVSSILFVVLKSALFFYYLFT
                     KLSLISVLVLHLKQENVLDQPGLEFKYPKPKRKSRFFIISMVLAVTCFIGYNMYLLYN
                     NTINTNISIIGHRGFEDKGVENSIPSLKAAAKANVEYVELDTIMTKDKQFVVSHDNNL
                     KRLTGVNKNISESNFKDVVGLKMRQNGHEAKLVSLDEFIETAKQSNVKLLVELKPHGK
                     EPADYTQRVIDILKKHGVEHQYRVMSLDYDVMTKLKKEAPYLKCGYIIPLQFGHFKET
                     SLDFFVIEDFSYSPRLVNQAHLENKEVYTWTINGEEDLTKYLQTNVDGIITDDPALAD
                     QIKEEKKDETYFDRSIRILFE"
     gene            complement(70270..71025)
                     /gene="pflA"
                     /locus_tag="RFE25_000162"
     CDS             complement(70270..71025)
                     /gene="pflA"
                     /locus_tag="RFE25_000162"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDU2815269.1"
                     /translation="MLKGHLHSVESLGTVDGPGLRYILFTQGCLLRCLYCHNPDTWKI
                     SEPSREVTVDEMVNEILPYKPYFDASGGGVTVSGGEPLLQMPFLEKLFAELKENGVHT
                     CLDTSAGCANDTKAFQRHFEELQKHTDLILLDIKHIDNDKHIRLTGKPNTHILNFARK
                     LSDMKQPVWIRHVLVPGYSDDKDDLIKLGEFINSLDNVEKFEILPYHQLGVHKWKTLG
                     IAYELEDVEAPDDEAVKAAYRYVNFKGKIPVEL"
     gene            complement(71048..73297)
                     /gene="pflB"
                     /locus_tag="RFE25_000163"
     CDS             complement(71048..73297)
                     /gene="pflB"
                     /locus_tag="RFE25_000163"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDU2815270.1"
                     /translation="MLETNKNHATAWQGFKNGRWNRHVDVREFIQLNYTLYEGNDSFL
                     AGPTEATSKLWEQVMQLSKEERERGGMWDMDTKVASTITSHDAGYLDKDLETIVGVQT
                     EKPFKRSMQPFGGIRMAKAACEAYGYELDEETEKIFTDYRKTHNQGVFDAYSREMLNC
                     RKAGVITGLPDAYGRGRIIGDYRRVALYGVDFLMEEKMHDFNTMSTEMSEDVIRLREE
                     LSEQYRALKELKELGQKYGFDLSRPAENFKEAVQWLYLAYLAAIKEQNGAAMSLGRTS
                     TFLDIYAERDLKAGVITESEVQEIIDHFIMKLRIVKFARTPDYNELFSGDPTWVTESI
                     GGVGIDGRPLVTKNSFRFLHSLDNLGPAPEPNLTVLWSVRLPDNFKTYCAKMSIKTSS
                     IQYENDDIMRESYGDDYGIACCVSAMTIGKQMQFFGARANLAKTLLYAINGGKDEKSG
                     AQVGPNFEGINSEVLEYDEVFKKFDQMMDWLAGVYINSLNVIHYMHDKYSYERIEMAL
                     HDTEIVRTMATGIAGLSVAADSLSAIKYAQVKPIRNEEGLVVDFEIEGDFPKYGNNDD
                     RVDDIAVDLVERFMTKLRSHKTYRDSEHTMSVLTITSNVVYGKKTGNTPDGRKAGEPF
                     APGANPMHGRDQKGALSSLSSVAKIPYDCCKDGISNTFSIVPKSLGKEPEDQNRNLTS
                     MLDGYAMQCGHHLNINVFNRETLIDAMEHPEEYPQLTIRVSGYAVNFIKLTREQQLDV
                     ISRTFHESM"
     gene            73885..74853
                     /locus_tag="RFE25_000164"
     CDS             73885..74853
                     /locus_tag="RFE25_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDU2815271.1"
                     /translation="MKSKIYILLLFLIFLSSCANTRHSESDKNVLTVYSPYQSNLIRP
                     ILNEFEKQEHVKIEIKHGSTQVLLSNLHNEDFSERGDVFMGGVLSETIDHPEDFVPYQ
                     DTSVTQQLEDYRSNNKYVTSFLLMPTVIVVNSDLQGDIKIRGYQDLLQPILKGKIAYS
                     NPNTTTTGYQHMRAIYSMHHRVSDVHQFQNHAMQLSKTSKVIEDVAKGKYYAGLSYEQ
                     DARTWKNKGYPVSIVYPIEGTMLNVDGIALVKNAHPHPKRKKLVQYLTSRSVQQRLVA
                     EFDAKSIRKDVSEQSDQSIENLKNIPLIPKSKLPDIPHHKFLEMIQ"
     gene            74850..76406
                     /locus_tag="RFE25_000165"
     CDS             74850..76406
                     /locus_tag="RFE25_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDU2815272.1"
                     /translation="MTAYKPYRHQLRRSLFASTIFPVFLVIIIGLVSFYAIYIWIEHR
                     TIHQHVDESQSSLHHTEKQIQTFITQHNNSFQELDLTNHHDVTATKRELLKLIHQQPA
                     TLYYELSGPNQFITNNYEHLNTKNMYLFSTHQLKFNNSTYMLKIYMANTPRLSEIKKD
                     SRQFALIVDQYDNILYANDDRFTIGEKYRPQQFGFMNESVKLNHADHRLIIYKDIHEN
                     IEDGITLLIVMAVVLVLLVIFGFISADNMAKRQTKDIETIIQKIYYAKNRHLGTYTPL
                     KNNSELEEINNYIYDLFESNEQLIHSIEHTERRLRDIQLKEIERQFQPHFLFNTMQTI
                     QYLITLSPKLAQTVVQQLSQMLRYSLRTNSHTVELNEELNYIEQYVAIQNIRFDDMIK
                     LHIESSEEARHQTIGKMMLQPLIENAIKHGRDTESLDITIRLTLARQNLHVLVCDNGI
                     GMSSSRLQYVRQSLNNDVFDTKHLGLNHLHNKAMIQYGSHARLHIFSKRNQGTLICYK
                     IPLSRGNVDV"
     gene            76399..77157
                     /locus_tag="RFE25_000166"
     CDS             76399..77157
                     /locus_tag="RFE25_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2815273.1"
                     /translation="MFKVVICDDERIIREGLKQIIPWGDYHFNTIYTAKDGVEALSLI
                     QQHQPELVITDIRMPRKNGVDLLNDIALLDCNVIILSSYDDFEYMKAGIQHHVLDYLL
                     KPVDHAQLEVILGRLVRTLLEQQSQNGRSLASCHDAFQPLLKVEYDDYYVNQIVDQIK
                     QSYQTKVTVSDLIQHIDVSESYAMRTFKDHVGITIVDYLNRYRILQSLQLLDRHYKHY
                     EIADKVGFSEYKMFSYHFKKYLQMSPSDYCKQAK"
     gene            complement(77516..78895)
                     /gene="uhpT"
                     /locus_tag="RFE25_000167"
     CDS             complement(77516..78895)
                     /gene="uhpT"
                     /locus_tag="RFE25_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HDU2815274.1"
                     /translation="MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLI
                     RNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLGKTLLGYFVDGRNTKRIISFLLI
                     LSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL
                     GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEE
                     LGWNRAEEIWEEPVDKENIDSQGMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGID
                     NWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLKGRRAIVAIGCMFMI
                     TFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFA
                     YLFGDSMAKVGLAAIADPTRNGLNIFGYTLSGWTDVFIVFYVALFLGMILLGIVAFYE
                     EKKIRSLKI"
     gene            79128..79622
                     /locus_tag="RFE25_000168"
     CDS             79128..79622
                     /locus_tag="RFE25_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002454321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HDU2815275.1"
                     /translation="MILSILLIFFCIRLVSLKISINHSKQLKADGAVEYGVKNSKFLA
                     ITHVLIYVLAGVEAFINKDTFSFANGIGLVILIFAYIMLFMVIKTLGGIWTLKLFILP
                     NHPIIKSGLYKITKHPNYFLNIIPELIGVLLLTHATYTTILLVPYAYFLYVRIKQEEK
                     LMNI"
     gene            complement(79983..80951)
                     /locus_tag="RFE25_000169"
     CDS             complement(79983..80951)
                     /locus_tag="RFE25_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDU2815276.1"
                     /translation="MKIGVFSVLFYDKNFEDMLDYVAESGLDMIEVGTGGNPGDKFCK
                     LDELLENEDKRQAFMKSITDRGLQISGFSCHNNPISPDPIEAKEADETLRKTIRLANL
                     LDVPVVNTFSGIAGSDDTAKKPNWPVTPWPTAYSEIYDYQWNEKLIPYWQDLAEFAKE
                     QDVKIAIELHAGFLVHTPYTMLKLREATNEYIGANLDPSHLWWQGIDPIAAIRILGQA
                     NAIHHFHAKDTYINQENVNMYGLTDMQPYGNVATRAWTFRTVGYGHSPYVWADIISQL
                     IINGYDYVLSIEHEDPIMSVEEGFQKACQTLKSVNIYDKPADMWWA"
     gene            complement(81006..82046)
                     /locus_tag="RFE25_000170"
     CDS             complement(81006..82046)
                     /locus_tag="RFE25_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDU2815277.1"
                     /translation="MTKLKVGVIGVGGIAQDRHIPALLKLKDTVSLVAVQDINTVQMI
                     DVAKRFNIPQAVETPSELFKLVDAVVICTPNKFHADLSIEALNHGVHVLCEKPMAMTT
                     EECDRMIEAANKNHKLLTVAYHYRHTDVAMTAKKAIEAGVVGKPLVARVQAMRRRKVP
                     GWGVFTNKALQGGGSLIDYGCHLLDLSLWLLGKDMVPHEVLGKTYNQLSKQPNQINDW
                     GTFDHTKFDVDDHVTSYMTFANRASMQFECSWSANIKEDKVHVSLSGEDGGINLFPFE
                     IYEPRFGTIFESKANVEHNEDIAGERQARNFVNACLGIEEIVVKPEEARNVNALIEAI
                     YRSDLDNKSIQL"
     gene            complement(82071..83147)
                     /locus_tag="RFE25_000171"
     CDS             complement(82071..83147)
                     /locus_tag="RFE25_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDU2815278.1"
                     /translation="MTIKVGIIGCGGIANGKHMPSLQKVENVEMIAFCDVDISKAASA
                     AEAYGTDNAKVYDDYKALLKDDTIDVIHVCTPNDSHCEITVAGLHAGKHVMCEKPMAK
                     TTAEAQKMIDTAKSTGKKLTIGYQNRFRPDSQFLHQAAQRGDLGDIYFGKAHAIRRRA
                     VPTWGVFLNEEAQGGGPLIDIGTHALDLTLWMMDNYEPESVMGSTFHKLNKQHDAANA
                     WGSWNPDEFTVEDSAFGFIKMKNGATIILESAWAINSLEVDEAKCSLSGTKAGADMKD
                     GLRIHGEDMGTLYTKHVELENKGVDFYEGNEMDEAEEEAKAWIDAVVNDTEPVVKPEQ
                     AMVVTKILEAIYQSAKSGKAIYFE"
     gene            complement(83221..84060)
                     /locus_tag="RFE25_000172"
     CDS             complement(83221..84060)
                     /locus_tag="RFE25_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDU2815279.1"
                     /translation="MTKKKNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNLYG
                     AKMIPDNATFKNYAFLLFDDSSQYLTWYKNTLIVASANALFSVIFVTLTAYAFSRYRF
                     VGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVK
                     GYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKIL
                     LRSPEKFTLAVGLFNFINDKYANNFTVFAAGTIMIAVPIAIVFLFLQRYLVSGLTTGA
                     TKG"
     gene            complement(84062..85330)
                     /locus_tag="RFE25_000173"
     CDS             complement(84062..85330)
                     /locus_tag="RFE25_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDU2815280.1"
                     /translation="MTKRNPKLAALLSVIPGLGQFYNKRPIKGTIFFIFFISFISVFY
                     SFLNIGFWGLFTLGTVPKLDDSRVLLAQGIISILLVAFAIMLYVINILDAYRNAERFN
                     RNEEIKDPKARMVATWDKTFPYLLISPGTFLLIFVVVFPLIFMFGVAFTNYNLYNAPP
                     RHTLEWVGLDNFKTLFTIGVWRKTFFSVITWTLVWTLVATTLQIALGLFLAIIVNHPV
                     VKGKKFIRTVLILPWAVPSFVTILIFVALFNDEFGAINNDILQPLLGVAPAWLSDPFW
                     AKVALIGIQVWLGFPFVFALFTGVLQSISSDWYEAADMDGASSWQKFRNITFPHVIYA
                     TAPLLIMQYAGNFNNFNLIYLFNKGGPPVSGQNAGSTDILISWVYNLTFEFNNFNMGA
                     VVSLIIGFIVAIVAFIQFRRTSTFKDEGGL"
     gene            complement(85333..86604)
                     /locus_tag="RFE25_000174"
     CDS             complement(85333..86604)
                     /locus_tag="RFE25_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDU2815281.1"
                     /translation="MSKILKCITLAVVMLLIVTACGPNRSKEDIDKALNKDNSKDKPN
                     QLTMWVDGDKQMAFYKKITDQYTKKTGIKVKLVNIGQNDQLENISLDAPAGKGPDIFF
                     LAHDNTGSAYLQGLAAEIKLSKDELKGFNKQALKAMNYDNKQLALPAIVETTALFYNK
                     KLVKNAPQTLEEVEANAAKLTDSKKKQYGMLFDAKNFYFNYPFLFGNDDYIFKKNGSE
                     YDIHQLGLNSKHVVKNAERLQKWYDKGYLPKAATHDVMIGLFKEGKVGQFVTGPWNIN
                     EYQETFGKDLGVTTLPTDGGKPMKPFLGVRGWYLSEYSKHKYWAKDLMLYITSKDTLQ
                     KYTDEMSEITGRVDVKSSNPNLKVFEKQARHAEPMPNIPEMRQVWEPMGNASIFISNG
                     KNPKQALDEATNDITQNIKILHPSQNDKKGD"
     gene            complement(86617..87714)
                     /gene="ugpC"
                     /locus_tag="RFE25_000175"
     CDS             complement(86617..87714)
                     /gene="ugpC"
                     /locus_tag="RFE25_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDU2815282.1"
                     /translation="MAELKLEHIKKTYDNNNTVVKDFNLHITDKEFIVFVGPSGCGKS
                     TTLRMVAGLESITSGDFYIDGERMNDVEPKNRDIAMVFQNYALYPHMTVFENMAFGLK
                     LRKVNKKEIEQKVNEAAEILGLTEYLGRKPKALSGGQRQRVALGRAIVRDAKVFLMDE
                     PLSNLDAKLRVQMRTEILKLHKRLNTTTIYVTHDQTEALTMASRIVVLKDGDIMQVGT
                     PREIYDAPNCIFVAQFIGSPAMNMLNATVEMDGLKVGTHHFKLHNKKFEKLKAAGYLD
                     KEIILGIRAEDIHEEPIFIQTSPETQFESEVVVSELLGSEIMVHSTFQGMELISKLDS
                     RTQVMTNDKITLAFDMNKCHFFDEKTGNRIV"
     gene            complement(88098..88676)
                     /locus_tag="RFE25_000176"
     CDS             complement(88098..88676)
                     /locus_tag="RFE25_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDU2815283.1"
                     /translation="MTKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNHK
                     GQGHSKWEDFFRGSRITETFGKYQHSPFDGKHYGIDFALPKGTPIKAPTNGKVTRIFN
                     NELGGKVLQIAEDNGEYHQWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHF
                     QRMKGGVGNAYAEDPKPFIEQLPDGERSLYDL"
     gene            88885..89511
                     /locus_tag="RFE25_000177"
     CDS             88885..89511
                     /locus_tag="RFE25_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDU2815284.1"
                     /translation="MAKVLYITAHPFNELVSNSMAAGKAFIETYQQQHPDDEVKHIDL
                     FETYIPVIDKDVLTGWGKMSNGETLTDDEQMKVSRLSDILEEFLSADKYVFVTPMWNL
                     SFPPVVKAYIDAISIAGKTFKYSAEGPQGLLTDKKVLHIQSRGGYYTEGPAADFEMGD
                     RYLRTIMTFLGVPSYETIIIEGHNAEPHKTEEIKATSINNAEKLATTF"
     gene            89700..90473
                     /locus_tag="RFE25_000178"
     CDS             89700..90473
                     /locus_tag="RFE25_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815285.1"
                     /translation="MKAHKIFWLNLAAIIIISIVVSGGMFLAMKWEQIHLKDGLKKVL
                     STYPIKNLETLYEIDGHDNPHYENNDQDTWYIESSYSVVGSDELLKEDRMLLKVDKNT
                     HKITGEYDTTTNDRKDATDSTYKSYPVKVVNNKIVFTKDVKDPALKQKIENNQFLIQS
                     GDLTSILNSNDLKVTHDPTTDYYNLSGKLSNDNPNVKQLKRRYNIPSNASTKVELKGM
                     SDLKGNNHQDQKLYFYFSSPGKNQIIYKESLTYNKLSEH"
     gene            complement(90786..92792)
                     /gene="ggt"
                     /locus_tag="RFE25_000179"
     CDS             complement(90786..92792)
                     /gene="ggt"
                     /locus_tag="RFE25_000179"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDU2815286.1"
                     /translation="MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVI
                     AIQLALNVVEPFASGIGGGGYLLYYEQSTGSITAFDARETAPEHVDKQFYLDDSGEYK
                     SFFDMTTHGKTVAVPAIPKLFDYIHKRYAKLSLEDLINPAIELAIEGHAANWATEKYS
                     RQQHARLTKYHETAQVFTHENQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQ
                     LVNVVKACGGTIILEDLANYDIQIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLE
                     HVDLPSMGPRSVDYLHHLIQAMHLAYSDRAQYLADDNFHEVPVQSLIDDDYLKARSTL
                     INSNKANIDIEHGVVSDCISHTDVEENHTETTHFCVIDKEGNIASFTTSIGMIYGSGI
                     TIPGYGVLLNTTMDGFDVVDGGINEIAPYKRPLSNMAPTIVMHHGKPILTVGAPGAIS
                     IIASVAQTLINVLVFGMDIQQAIDEPRIYSSHPNRIEWEPQFSQSTILALIARGHAME
                     HKPDAYIGDVHGLQVDLNTRDASGGADDTREGTVIGGDVLSIRKQPLPSPKIYDNDTH
                     RVYFNDMQLPLYAEQVRWMHDKYWVDESVIRIIFPEVSVHIEDLRSYEIAGKNYIDIA
                     WLARKKGYQVTLKDDSLYLTDETYHSVKANTNAYYRYDRDSITR"
     gene            complement(92830..94605)
                     /locus_tag="RFE25_000180"
     CDS             complement(92830..94605)
                     /locus_tag="RFE25_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDU2815287.1"
                     /translation="MKKIISIAIIVLALVLSGCGVPTKSEVAQKSSKVEVKGERPTIH
                     FLGQASYENDMNIVKDQLENAGFNVKMNIQPDYGSYRTQRQAGNYDIQIDDWMTVFGD
                     PNYAMTALFSSTGSNSLLKDKHVDQLLNKASTQNEADVKQTYKQIEDEVVFDKGYMAP
                     LYGSKKNLVYDNKVLDKNSVGLPNSRALIWQQFDYNNSRERDTRPLVMTQQDGEIPTL
                     DPIRSIAPSVYSINMNMYTRLLLLDENDHLTTKGSLSRDYAVNKDNKAFYFLLRDDDY
                     FAKVVNGQARNTGERVSAEDVKFSLDRARDKKSVPNNNTYNMHKHINDIKILKDEDID
                     QLRKEKDKDDKSIYDKLIKAYNVKSLTTDGQKVNNKDGIYQIVKITTDQSMPREVNYL
                     THSSAGILSKKFVNQVNQEYPKGYGDSSTIPANSDGKNALYASGAYIMTQKNAYQATF
                     QRNPGFNETEKGSYGSPKIKNITLKFNGDPNNALSELRNHSIDMLADVNQKHFDLIKS
                     DKNLSIIRKNGRKSVFLMLNIKKGIFKTHPNLRQAVVNAIDQDQFIKFYRGDKFKIAS
                     PITPLVDTGNEQRQDLEKVEKAINQ"
     gene            complement(94622..95785)
                     /locus_tag="RFE25_000181"
     CDS             complement(94622..95785)
                     /locus_tag="RFE25_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815288.1"
                     /translation="MVKLTTKIASLKLFASYAIATYILVMLTSALNLFKGYVADTFYI
                     AETLLIILTIILIIILTTEQTWKHHDLWRRIVEVLLLLMALTGNVFTLLMFVSIRRYQ
                     RTSQIHSYNGWESFIRKTTRHRIAIIGLLILVYMLTLSIVSQFTFDTTLATKNQFNAL
                     LHGPSLAYPFGTDDFGRDLFTRVVVGTKLTFSISIISVVIAVIFGVLLGTIAGYFNHI
                     DNLIMRILDVVFAIPSLLLAVAIIASFGASIPNLIIALSIGNIPSFARTMRASVLEIK
                     RMEYVDAARITGENTWNIIWRYILPNAIAPMIVRFSLNIGVVVLTTSSLSFLGLGVAP
                     DVAEWGNILRTGSNYLETHSNLAIVPGVCIMFVVLAFNFIGDAVRDALDPRIH"
     gene            complement(95791..97269)
                     /locus_tag="RFE25_000182"
     CDS             complement(95791..97269)
                     /locus_tag="RFE25_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815289.1"
                     /translation="MNCTFRLLTSNKFDMMLCLPIHKCVNLFYTFVYHSNLLKIILQG
                     VIIIITYLESFKSLYHKAFYKFVLSVLSLPIFLYAVIKFFFSAKRKNFYANNSEISEI
                     ERALHQKYKYLSQQKSSTQIHKEALKIFKAQSSNTSSKNIEQAHFSTYFENLLFHKFI
                     MIKVILALPMFILLTIYLQPLVRYIFERIVMAVIVIIGVIVSVFTILYFSPLDAAYSI
                     LGQNATKAQIHQFNVLHHLNEPYFIQLWDTIKGVFTFDLGTTYKGNEVVTKAVGERIP
                     ITIIVAVLALIVALIIAIPIGIISAMKRNSWLDITLMIIALIGLSIPSFWQGLLFILA
                     FSLKLDILPPSYMPEHPISLILPVLVIGTSIAASITRMTRSSVLEVMRSDYVLTAYAK
                     GLSTTQVVIKHILKNAIIPIVTLVGLLVAELLGGSAVTEQVFNINGIGRYIVQKQLIP
                     DIPAVMGGVVYISIVISLANLIIDIFYALIDPKLRSEINERK"
     gene            97226..98818
                     /locus_tag="RFE25_000183"
     CDS             97226..98818
                     /locus_tag="RFE25_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815290.1"
                     /translation="MSNLLEVNSLNVQFNYDETTVQAVKNVSFELRKKHILGIVGESG
                     SGKSITAKSILGLLPDYPDHTLTGEIIFNGQSLNNLSTSALQQIRGKDISMIFQDPLS
                     SLNPRLTIGKQITEVLFQHKRVSKSEAKSMTINILEKVGIKHATRQFDAYPHELSGGM
                     RQRVMIAMALILKPQILIADEPTTALDASTQNQLLQLMKSLYEYTETSIIFITHDLGA
                     VYQFCDDVIVMKDGSVVESGTVESIFKSPQHTYTKRLIDAIPDIHQTRPPRPLNNDIL
                     LKFDRVSVDYTSPSGSLYRAVNDINLAIRKGETLGIVGESGSGKSTLAKTVVGLKEVS
                     EGFIWYNELPLSLFKDDELKSLRQEIQMIFQDPFASINPRFKVIDVIKRPLIIHGKVK
                     DNDDIIKTVVSLLEKVGLDQSFLYRYPHELSGGQRQRVSIARALAVEPKVIVCDEAVS
                     ALDVSIQKDIIELLKQLQLDFGITYLFITHDMGVINEICDRVAVMKNGEIVELNNTED
                     IIKHPQSDYAKQLISEVAVIAK"
BASE COUNT        31791 a        18209 c        15490 g        33593 t
ORIGIN      
        1 aatttatcgt tatacttttt cgtttcttca gaacgtttat cattcgataa atctccgtta
       61 tttttaatct catttaattt attaatcaac gctaactttg taatatcgtt atcatctaaa
      121 taagtggcaa tattaatcgc ttcatcaaga tgtccttgtc ctaattccat ccaatataat
      181 aagtagtctt tgtttgaatt tggtgtcacg ttattaagta aattttcttt cttatctttt
      241 tctaaacctt gtttatttgt ttggatataa cttttggcat aaatgtaaag tgcctcttta
      301 tctaattttt ttccatctaa atcatcatac gtatttagta cttgcgtata atcatccttt
      361 acaaatgctt ggtatccttt ttcaatgcgc tcattatgct tcattactga aaaatataaa
      421 aaggctaaaa atgcaattaa taacacactt aacgttgtca tgccgatagc aacccatttg
      481 aaaacggtat gccctacttt gcgtacatat gcataatttt gactataatc ttgttcttgt
      541 ttctgatact gttcatctaa aaatgccgtt agtaaatcta acgttgccgc ttcaataact
      601 ttagtttcaa atggcgttcc tttatgtagt tctaagtttc cttcaactaa agcatcaaat
      661 gattgtttct cattgaatgc acagataacc agtgctttat atcttgttaa aaattcagct
      721 tctgacaccg gtaatggatc aacaacattt tgtaaacctc ttgttttagc aattggtaat
      781 ccatctcttg tgaaaaataa ctcatctggt gccaaaacaa atgtgtaacg tgtacgattt
      841 acttcttcta aatttttgat attgagtaag tatcgtaatt tttcattttt agtaaatgat
      901 ttaatattat caaaaggtgt atgattgtca ttaatgtcat aatgtatttg gaaactgtca
      961 cgtagttcag ttaattcagc atctataaaa tatggagaat gttgttctaa taagtacatt
     1021 aaatgaaaat gttctggttt aattgaagac ttaggaatct ctctcatatc taagcgtaat
     1081 tttgttttag ctgcttcttc agcatctaaa ggcgttaaca tatcttgcat ttcattttta
     1141 gggttatgat ttttaaccat ctatttttcc tcctatagta acttcaaaat atctccatca
     1201 gcgatttgat aatcaatgag tcgatcattt tcaacaagta attgaccttt cgtcatcact
     1261 ttaatttgtg tattgacatc aaatattgaa atgtccaaac tatccaatac taaagctatt
     1321 aaatttttta tcggtaaata tgctggtact gctaagtcat atgtgccgta attataatta
     1381 gtaaaatcaa atgttacttt tacgtgctga ttcatttttc gttcgtctcc ctttatgaat
     1441 tgaaaaaatg acaaatccta aagtcaaaaa agcccctaca gacatcaaaa tgtacgggaa
     1501 tatttttttc tcctgcttgt tttgaatata ggggctttta tcactctccg aagtcttttc
     1561 taagttagat ttggaaaata acactttttt agtttcattc aagcgagtcg agtgactcgc
     1621 ttgattttga aacatatcat tttttatttg ttgttgtcgt tcttttttct gcttagcaat
     1681 cgcgtcgttg acttctttac tatctttatt aaatagcgtt gtatcatatt gatttaaatc
     1741 attattgatt cgcttttcct cttcttgttg cacatcaata ttaagtccgc cattattgct
     1801 agatgctgtt aaaaaagtta aagcaatcac gctattcatc aacattagat taatctctct
     1861 ttcttaaagt gttttataaa catgttcagt acaaaaccaa taatcacaag tactgttaat
     1921 attactagtg ccaagcctat aggatgctct gcatttaaat aattgaagaa catgttatcg
     1981 atataagaca atggtgaaat tttattagtc acaccttgtc cagccgcttt caaattattc
     2041 atagctacaa agtatagacc caatgcagca atcattaaga acataccgat agattttacc
     2101 tgtcttagta aatacgtatt aataagtaca aagaccatca tagttaaaat caccattaag
     2161 atgaatttcg ctctatagcc agctaataca tggaacttat tcattgcaat taaaccgaca
     2221 attaatcctt ctaccaaacc agttgtacca ataacacctg acgtaatgac attattccaa
     2281 agatggtttt tactactata atcatcttta atgaaattca tttgaccttt ggcacgttca
     2341 taactataga aaatatatgc tgtaatcatt gatagtaaat acatcaataa tacgaataat
     2401 gtcggtgaaa tcacctctgt attaccatta ttagctaaaa cattttctaa gtttttcttt
     2461 tgaaccggat tactcataaa tgcttttaat gcttggtttt gtctgtcgcc atctttagaa
     2521 ttttgtaata cttttttaaa ctctttagcg aataactcat tatctttatc gtttttagcc
     2581 atttgacggt tcaaatcatt cgctcttacg cctaatgctc gacctgtcgc atgtagttta
     2641 ttcacattat tatctaattg atttaattgt ccactaactg aatctgcaat tgtttttgat
     2701 tcttgtgtat cagatagcaa ttgcgtgctc ttttcagaaa ttctgctaat ttctttatct
     2761 aagttagaag acattgtgtt gaattcatca tttttgcctt tgtcaatttt tggttcttgt
     2821 ggttcttcag caaaagtctt tttaacgttt tctaactgat caatcagctt agaaatatct
     2881 tctttatttt ttgttgtatt ctttttgtta tttaaaatgt catcaatcag ttggtctgag
     2941 ttttcttcca ttgaatcaat ttgatgtaac acagctactt tatcgtcttt gaaactttcc
     3001 atgtcattga taacttggtc aaccatcata tcaattaaac gtttgttatc gaatggttta
     3061 tcttctctgc cttttgtatc tgtgtacatt ttataatgtg catcaaacct agataatgca
     3121 ctcaattgct ggcttaatgc atctttcgat aagcgaccat caaggttatg attcaatgtt
     3181 acatccacaa cactcgttgc tttcttatca tttggttcat cttgacgatt tgcttgtcca
     3241 aataacaatt gtaaatgcat tgttttatct tttaagaaat ctttctcagc atcctttttc
     3301 aatttagcaa cgccattgac ttcaacttta tattccttgt tagatgtatc gagttgaaca
     3361 ctttgatcct taatgtcata ttttttacca ttaattttaa tgtcgccttc aaagttaaaa
     3421 tgaggatctg ttgcaacagt taattgatta atatcattac ttttaatcgt ttcagtacgt
     3481 tgcactttga caccatcatt aatcaaacta cttgtgtctt gcgcaacttg gttatcgtaa
     3541 tctgttaaat taatgtgttc tgctaacggt tttttcaaat tatattcgtt tttataacgt
     3601 tttgcttctt tgacaattgc ttcgtattta ttagcttcac cctcatttaa acctgcagct
     3661 ataaagtctt gtttagacat gttatagata aatgttgtat ctgtatcagg ttctttgaca
     3721 atatcatcat gaagttgttt ttctaagttt tcagcgaatt gagcattgtt cattttaatg
     3781 ctatttagcg catcttgtaa gtctttgtta tttgcaagct catcttgcag tgattctgtt
     3841 aattgcttac ggtagtcttc aatcatacct tttgaaaatg gtgactcttg tgattgaatg
     3901 atttctctta atttatctaa gttttcttta acagtttgtt tatattcttc tttacctgta
     3961 tcttgcatac ttgattgttg atcaatttgg ctgtccatct gttttaatgc attgatatag
     4021 ttatcaagtt ccacactatc tttttgcgat ttataatctt gtaacatttt atccatcgct
     4081 gtattgtgct cgtcaaataa tgaattttgt ttttcaatta aagtcgaaac attataatct
     4141 gtgttcaccc tgaacgtatc tgaattcgca ctcaataatg atttattgta tgtttggaac
     4201 cattttgtaa tgtctttgtt tgcagaaatt gaatttacaa gcgtatctgt aaataattcc
     4261 gggaagtcgt taattggatt taataagtaa ttcgagaatt tactattcac accatgttca
     4321 cgcgtcataa tagcgccaac atttttttgt gcattatgta aattatcaat gatgcttgtt
     4381 aaataaattt cgactaagtt tttgttaaag tcgttaagta cattacttac aactttttct
     4441 gtgtttttag ctacttcttc tttttgtcct acagctgttt tatactgtag cgatattttc
     4501 gatggtgttt tagcgtctaa ttgcattgcc aattttgaaa agttttctgg gataacaatc
     4561 atgacttggt atccaccatt tttcaaacca gactcagcaa cgtttcttgt tactgtttca
     4621 aatttatagt ttttctcatt tgctaacctt ttaataaatg cttgacccag ctcaactttt
     4681 ttaccattat atgtcgttgg ttgatcctcg ttaacaattg cgatatgtat tttattattt
     4741 ttattactta cactttggga tcctttttct gattgatctc catattttgt ttgaacaaaa
     4801 aatatcatac taactatggc aattataata attaaagtga caattaatgc ataaatccaa
     4861 tttttctttt tcatgcttat ttcctttcag ttgttttctt aaaaaatgat aagcaaagcc
     4921 acattagaaa atgtgacttt gccaatttca gaatgcttat tgcaaaccga aattattaga
     4981 aagttgttgg tcttgttctt gaacggcatc agcagtgcta ttcaattgtt gtttaatttc
     5041 ttctaataat tgtgcaaatt tttctacttt aggactaagt tgttggaatt gctcttcgaa
     5101 acggctgaaa gcttgacctt cccagttcgc tgcaatttca ccttgtgcac gtgttaaatc
     5161 agataaaatt tgacggattt ggtctgaacc ttgcccgtaa gattgcgatt ttgctctgat
     5221 ttcctctgga ctcatcttaa tcattgccat aactagaaac ctcctgaata ttttaagttt
     5281 atcaaaactt tttagggaca ctattttttg aaaaagtgct ccttactcaa ataatatata
     5341 aattattagt atatgtatat agttttttaa gtatttttag ctttttttaa ataaatatat
     5401 tgaatatacc catatatttt taattaacca ttcatttttg taatataaat gtgtatacta
     5461 aaattaaatt aaatacataa aggattaaat ggttattatg aagaaaacaa ttttactgac
     5521 gatgacaact cttactttat ttagtatgtc gcctaactcg gctcaagcat atacgaatga
     5581 tagcaaaaca ttagaagaag caaagagagc acacccaaac gcacagttca aagtgaataa
     5641 agacaccggc gcgtatactt atacatatga caaaaacaac acgccaaaca acaatcatca
     5701 aaaccagtca cgtacaaacg acaatcatca acacgcaaat caacgtgatt ttaacaacaa
     5761 tcagtaccat tcttcattaa gtggtcagta tacgcacatt aatgacgcaa ttgattcaca
     5821 cacaccgcct caaacgtcac caagcaatcc tttgacacca gcaataccga atgtcgaaga
     5881 caatgacgat gaattaaata acgctttttc aaaagataac aaagggctta ttacaggcat
     5941 cgatttagac gaattgtatg acgaattaca aatcgccgaa tttaatgaca aagcaaagac
     6001 tgctgacggt aaacctttag cattaggtaa cggtaaaatc attgatcagc ctcttatcac
     6061 aagtaagaac aacttatata ctgctggaca atgtacatgg tatgtctttg ataaacgtgc
     6121 caaagatgga cacacgatta gtacattttg gggagatgct aaaaactggg caggccaagc
     6181 ttcaagcaat ggcttcaaag tagatagaca cccaacacga ggatcaattt tacaaacagt
     6241 aaatggtcca tttggtcatg tagcctacgt tgaaaaagtt aatattgatg gaagtattct
     6301 aatttcagaa atgaactgga ttggtgaata tatcgtttca tcaagaacca tctctgcttc
     6361 agaagtttca tcatataatt acatccatta aattaatcat gacatcaata aaaagcgacc
     6421 agttcgcagt ttacaattcg taacactgca aaattggtcg ctttattttg tatgttattc
     6481 gattattaaa tatgatgttt accttcaaaa ttgcaataac ttgtcacctt aaagttaacc
     6541 gacatttttc aagaatcatt atgtaatcaa actatttttt gtagtttatt agattttcaa
     6601 taacttatta aacattatta taactaaaat tctattaatt taaacaaaat ttaaaataaa
     6661 ccatttaata aaatgtattg ttctgatatg attaactcat aaataattgg gaggaagcaa
     6721 aatgtctaaa aagttaaaaa ttataattcc tattattatt gtcttattat taataggtgg
     6781 aatcgcatgg ggagtttatg cattttttgc aaacacaccg aaaaatacat acttaaaaag
     6841 cgaacaacaa actgcaaaaa tgtataaaga ttattttaat gaccgttttg aaaatgaagt
     6901 gaagttccaa gaaaagatga aagataattc gtttttatct tcattagaat taagcgcaga
     6961 tgcatcagat gaaattgtta aggggcttgg tattcctaaa tctgttgtta atgcttcgaa
     7021 aattaaaatg tcatatggac atgatcctaa aaaagagaaa tcaatgatta atcttgaacc
     7081 aacaatcgca gactctgcat tagggaaatt ccagttagct gcagataaag ataagcatta
     7141 tttcgaatca ccattattta aagggaaata tagtgttaat aattctgatt tattatcaac
     7201 gtattcaaaa cttacaggtg aagatgaaga aacagcaaaa gaaaatggta ttacaaacca
     7261 acaactaaat ttaaatactc tttttagtaa tgctcaagca caacaaagtg actacagcaa
     7321 aattgccgaa aaatattccg aacttattgt cgacaaatta gatgacgata attttgataa
     7381 aggtaaaaaa gaagaaatta aggttaatgg tgaaaagtac aaagttagac ctgtcacgtt
     7441 aacacttagc agagctgaca ctaaaaaaat tacattagct gtattagaag aagctaaaaa
     7501 ggataaagac cttaaaaaat taatggaaga acaaggtgct acaaaagact atgataagga
     7561 catcaaaaaa gcaattgacg atgtcaaaga aactaaaaag gatgaatttg ctaaaattca
     7621 atctaaaatt tataccgaaa aacatacgat tgtaaaacga gaaattacta ttacagacaa
     7681 agaaaataat aaaactaaaa tcaaaggtac taatacttta gaagacgata agttaaaact
     7741 agattacgca cttgatttcg atcaagataa atacacgtat gctgaagcga aatatacaat
     7801 taaaggcgta tcttctaagg aaaaagacaa taaatacagc gataaatacg aatttggtaa
     7861 aaagacagaa tatgatgaat caaaaatcaa attagataac caagaaaaag tagatggcac
     7921 aaaacgtcaa gataaaggta aaatcactgt cgcattagat aaatatagcg acgaaaatga
     7981 attcactttt gaaaataata tagattctga cgtaaaaaat aacactcaga aatctacgtt
     8041 aaatatcggc atcaaatatg ctgaagaacc aattaatttc attttaaaat ctagcacaaa
     8101 attgaaagca gatattgatt ttgatgatag tggtgcgaaa gatttcaata gtctatcttc
     8161 aaaagaccgt gaaaaacttg aaaaagaaat cgaaaaaaat ggcggcaaaa tgtttgaatc
     8221 aattttaaaa aaggcatcta aataactaaa atataaaaat aagattgaaa ggtcatcttg
     8281 cctttcaatc ttatcattgg aggagtggtt aaatgaaaac aatacatttg tttcgcatct
     8341 accactcttt tttattgaaa aagtggtatt tgattatcta tttactattt atcttagcgg
     8401 cactccttat tacattaacg acgatccaac atgtaacaga agatgacaat cattttaata
     8461 taggtgtcgt agataaagat caatcaagtg aaacgaaatt aatcttaaac tctattggta
     8521 aagggagtaa cctaggaaaa aatgtaagca ttaaagcata tgatgataag caagcacata
     8581 ctttgttaaa aaaacataaa cttcaaggct attttgtttt tgataaaggt atgaccaagg
     8641 cattttataa acaaggcgaa ctaccaattt cagtatatac atatgatcaa caatccatga
     8701 aaagtgtcgt gctatctcag ctaacagatt ctgtttacca acgtcttatg cgatcaatgg
     8761 gtggcatctt agcttttcaa gacttagcac cgaaagcatc acattctgac agtatcaatg
     8821 ttatgactga tttgctgatt acaggattaa accgttcagg tgcatttaac ttagaaccga
     8881 ttcatttata cgatacgggc agttattatg caattacagg atttttagca acggtattca
     8941 tctttgcact atctttattt acagttttga aaatgaatca agatactgta ttgaaagcgc
     9001 gattgaaaat gtttcatttt tctaaagagc gtttattaat cattcgtgcg ttgattacat
     9061 ggttttatac tatgttatgg agtatcgttg gtgtagtttg gattgtgttc agtattccga
     9121 atacttttga attatataat tggccaacgt tagccattca tttaagctat tatgttacct
     9181 ttttaatact gtggttatta ctcatcgaac ttttaacaac aggcttgttg aatagtatta
     9241 gtaaagtcat attagctatt gtcatcctgg tgttatctgg tttaacaata cctacgattt
     9301 ttttacaaca tatagcaaat ggcgttttca atattcaacc gttcgcagtt gtaacaaatc
     9361 aattgttaga aattatttta aacaactaca ttttagaact gcaccctagt ttctatctta
     9421 gcttcatcgc acttttgata attaatttag ctgtattggt ttggaggtat cgtcaatgaa
     9481 gccttatata caacttgttt tgttcaagca atggttacaa tacatcttgc tcgtaacaac
     9541 cattgtcatc gcactcgtac ttattggtat cggttaccgt gtagcacatg acaacttcaa
     9601 aataccgatt accattcaag atttagacca aaccactgca tcaaaatcat tcgtcaataa
     9661 aattaaacaa tctgactatg taactattaa aaaagtcgat gaagatgaaa gctatattga
     9721 agatgatgtt actaaaaagg aagctatttt aagcatgcaa attcctaaag gtttctctca
     9781 aaaattaaaa gagaaccgtt taaaagaaac gatacagtta tatggtagag atgactttat
     9841 aggtggtatt gctatagaaa ttgttagtag ttcattatat gaacagcaaa ttcctaacat
     9901 tatttatgaa caccttgagg atatgaaaca gcatcaatcc atcgatgcta tcaacaagtc
     9961 ctatcataaa catacacctg aatctaaaat caaatttgtg tcgcttacta aacaagcaca
    10021 acactctatt tcaattagct taatctttgc ggtgatttta tttgttagcg ctgttcaagt
    10081 agtacttcat tatcgtttaa accaacaagc agcattgcaa cgattatcac aatatcattt
    10141 aagccgtttc aaactatata gtacttatgt aatgacacat acgatcttgt tattgttggt
    10201 actattggca gttagtctat atttgtctca accactcagc ttaatatttt acttaaaatc
    10261 attgttactt atattgattt atgagatagg tatcgtcttt atcttattcc atattcaaac
    10321 aataagtcat cgtttattca tgacatttat atatgcactt gctatgggta tcgtatactt
    10381 gattattttc atgtaaagga gcgtaactga tgatagaaat taataatctt tcaaagcgtt
    10441 accgtaacaa acagattttc aatcatttaa ctatgtcctt tgatagtaat cgtttaaccg
    10501 tattacttgg tgataatggt gctggaaaat caacattact tcgtatgatt gctggtattg
    10561 aaaaagctaa tgatggaact atcaactatt tcggcgaaaa atggaatcaa agacaaatac
    10621 aaaatcacat cggttatgtg ccacaagaca ttgcgttatt tgaacacatg acagtggctg
    10681 aaaacattaa attttttaaa tcactttgta aaaatccaat taatgataca actatcaacg
    10741 aatatttaca gcaattaaac tttgatgata cgtctgccaa agtatctaca ttgtccggtg
    10801 gaaataaacg taaaattaat atattagtag gtttactagg tcaacctcga attctcattt
    10861 tagatgaacc gacagttggt attgatttaa aatctagaca tgacatccac caactactta
    10921 acatcatgaa atctaaatgt ttaattatat taactaccca tcatttagat gaagtggaag
    10981 cacttgcaga tgatatcaag ttaattggcc aagatccttt ttatcaacat gttttagagg
    11041 acaagcaatg ggcttatacc tattattaaa acgaaaaaat cccaagttgc gtatgatatt
    11101 gtaacttggg atttactgta ttatctactt tgcaagtatg acgttgggtc tactgcatat
    11161 tgattaccga tgccaccaga catacgttgg aagtgtacgt gaggcgctgt tgaattaccc
    11221 gtactacctg aatatgcaat ttggtcacca gctttgactt tatcaccagc tgaaacagtt
    11281 aaacgattat tatgcatata ccattggtag ttattactgt tcgcttcttt aatagttact
    11341 tgattgccgc caccatagtt actccaacct gcttgtacta ctgtaccatc agttaatgag
    11401 taaactggtg aattttcagg cattgcatag tcgacaccgt aatgcgcacc accaccgtga
    11461 tattgtccat atggttgtag ttgtttacga cttgttaacc agcttgcgtc tttcgcatga
    11521 ccactagctg tcgctttact tgctgatcca ccattttgat tagatgtgcc attaggataa
    11581 ttgacctttc cattaccatc atggctgtta tacgcttggt tgttgttact atgtgaataa
    11641 tagctcgcgt ctggacctac atttgattga taaccatatt gattaatatg ctgttggctt
    11701 tgactcgctg tgtagtcatt gttatctcct gctgttgctg gattcacata tgtttggccg
    11761 cttccattgg catttgcatt ttttggataa cagttataaa aataatgcgt atgtccttga
    11821 gcatctacga atgtatagct atattcttta ttatcaaaca ttgcttgatt ccagttacca
    11881 tcaggtgtgt gatgataatc cccattagaa tcaattgtat aataagtacc ataagatacg
    11941 tcttgtgatt gtgttgacat tagtgtatgt gcttgttggg tgtttgtcgt ttctgctgca
    12001 tctgcttgat gcgccattgt aaatgtagcg aagcccatcg ttgcaatcgc tgctgctgtt
    12061 aattttttca tgtataaaac atcctccatt aaagttaaag ttagttttca attaaactgt
    12121 actgcacata ctaaaagaat tagacaactg agtaaaggat ttaattctca ttttccaact
    12181 atttaatatt cccgaaatgt tttactaaac tcattacatt gtcattacaa aatagccata
    12241 cattgatatt aaaatgacat ctctcactgc attcgcttaa gcttttataa attttcaaaa
    12301 ttaacaacta atcattcgtc catgttcgcg gttcaacgct aatgtatgat agtaatcatc
    12361 catcaaatca tatcaaccaa attccattct caatcgctat tgattgtcat tcaactttct
    12421 aatagtgata tgcttctcag gcttaaaaat cgtcatatct tttctattaa ttaaatcatc
    12481 tgtgagcttt aatgctacta tttcattgct gccataatac ttaatatata acgttcttgt
    12541 agttaaattt attacggtct gatacatcgt atagtgattg tcagcatcat gcggacgtac
    12601 aattccaatc ggtatattta ccgcatctaa taaataaaat gcattcatta aatccatttc
    12661 tttatcattg ttttgagcaa tgtttgcttt cataaatgcc attctcacaa agcgctcagt
    12721 tgaagtaaat ccacctggca atccaaatgt acctgcttca ttgcctaaag gttcaatcgt
    12781 tacaccttcc aataactttg ctgttgctgg ataaggagaa atattgatat attgtcttaa
    12841 attactataa tgccaatcta agtctggatg atttgttaag acaccaatag ggttatcttt
    12901 tataaccact tccccctctt taaatgaaac ttcgactgaa tgtccagttg catcggaaac
    12961 atgataatgc aatggcggaa cttcaccgat gtcatttaaa tataccgcta caacatgtat
    13021 ttgggatgct tgttgtttca tatcttcaat gcttgttgta tatcccaaaa tccatgtcac
    13081 aatttcattt tgcgtaatat tcatcgcgtc cgctttgtgt gttgagccat atgaactata
    13141 acctcggaaa tattgtgtcg aaatagcaac gccatgttca ttaacaccat caccataaat
    13201 aaaaccttcc atatctgttc ctgtaccaat aaagccatat tgcgtttggc ctgtcgtgcc
    13261 agtgcgagat gtccaacgat aatttctagg cgtcactgct ggcgaaccat ctaatggata
    13321 atcataatcc atcgtgcgtc caagaagtac ttgattattt aaagtttgta ttgtgaatcc
    13381 tgtgcacatt gttctcactc ctctgtacct tcatttactt taatcacttt caaataaagc
    13441 tgtttcactt aaacatacta taaaaaatca atcatacaag caattaattg atattcattc
    13501 tcaataactg tggtatgata tgtaaggaaa tcatgactta tgtgtgagtg aacgatcatc
    13561 tatacatccg ttcacttcat ctcatgactt tctatattta atttttacaa ggagtgacat
    13621 ctgtgaataa cacacaatct tcaccacgca gtaatattat tattgcgatt atgttgtctg
    13681 cattaacata ttggttgttt gcacaatcat ttattaatat aggacctctc gttggtcaaa
    13741 cgtatcaaac ctctcctgcc gtgttaaatt tatctattag tttaacttcc ttcgccacag
    13801 gtatcttcat ggtggctgca ggtgatattg ctgataaaat aggacaactg agaatgacat
    13861 acatgggtct cataatcagt atgtttgcat ctcttctatt aattatatcg gacatcactg
    13921 cactgctcat catcggtaga attttacaag gtttatcagc agctatcttg ttaccttcaa
    13981 cagttggcgt tttaaataat caatttaaag gagaacattt aagacgagcg attagttatc
    14041 taatgattag tactgttggg ggcatcggcc tagctggtgt tatcggcggt ttaattgcta
    14101 caaatttcgg atggcaaatg aatttcatca ttagtatagt cattgctttc attgccatat
    14161 tacttctaaa aggcacacct gaaaaagtaa gtcaacatag ccaccgtcat ccgttcgatt
    14221 acaaaggtat gtcgattttc gctgttatga ttggtagctt tacattattg ttaacacaag
    14281 gattcgaaca aggttggttt agtacattct cattcatttg tctgagcatt tttatcatca
    14341 ctacgctgat attcatcatc atcgaacgtc gacatgaagt accttttatt gatttctcag
    14401 tattacgcaa ccgtccgttc attggtgcat ttttaaataa ctttgtttta aatagcggtc
    14461 taggcgttac agtggtcttt ttcatatatg ctcaaacaca ccttggttta tcagctgcgc
    14521 aatctggact tgttacattg ccatatgcca ttgtggcagt tgcgatgatt cgtttaggtg
    14581 aaaaagcaac attacgtttc ggtggcaaat tgatgctcat cattggtccg ttgttccctg
    14641 tcatcggcat cactattatt agcatgactc aattatcggc atcacaatat gtcattgcag
    14701 ttatcattgg tttcgtcatt tgcgcaattg gaaatggttt agtcgcaaca cccggcctta
    14761 caattgcaat tttcagtatg ccaaatgaaa aagttggttt agctacagga ttatataaaa
    14821 tgagtggtac attaggtggc gcctttggta tagcactaag tactacagtt ttcagtatgt
    14881 tacaactaaa ctatgcacca agtgtagctg caaccgtaac atttatcgtc agcattgtat
    14941 tgatgatcct tggctcattg tctgcataca tgatcattcc aaaaacagtt aaatcttaaa
    15001 tataatagaa gaattatgtt tcgaaatatc tttatcactt taaaatgata tacaagaaat
    15061 tcaagaaaaa taagcgaaga acgtttttct ctgttcttcg cttactctaa ttatattcac
    15121 tatcaattag acaaaatggc cattttcaaa tatcacgcgt tgtttctgac cttgaatata
    15181 tttattataa ttctcttttt gaaaatcagt taacattaat ttagatgtac cgtattttaa
    15241 cactttttgc attgtttcta ttctcatttt tctaaataac catccatctt ttaacacaat
    15301 acgattaaca gcatcatatg ataattctac tgtttcttta atttcaaatg tcttgaatga
    15361 aataatcgtg cacattaaaa acgtatcacc aaagtaataa acatctaaat catcacgttt
    15421 atgttgtcca actaacaaac gaccatattc gaactctttt tctggatatt tcaattctaa
    15481 aaaactaata atctcttctt cttttaattt gaattgcatt taaaaacatc ctctcttaag
    15541 ttttaacaag ccttaattaa aaattttttc aatcacatag ttcaatatac atcatttcgt
    15601 tatgtttttt aatactttgt tcaaaaacaa atattttatt ctttaaaata atgacttttg
    15661 tatttttcat cacaataaac attttaaaat tcttgttatc ataatcatta aaaggtatta
    15721 accttaataa tatattctct cgtctcaacc ttaatcgtat acttcagacg tctgtttgta
    15781 gacaataaaa gtcattcacg tcttcatatg tcatcaaatg tttatcatga tatgatgaat
    15841 ataataatcg ggtatataac tgtatgatta attacacaat aaagagaagg aatataatat
    15901 gaaaaaagtg tcaattaaag atgttgctag agaagctggt gtatcagtta caactgtgtc
    15961 acatatttta aatcataatg atagtcgttt ttccgcaaca acgataaaaa acgtacatgc
    16021 tgtttcagaa cgtttaggct atgcccctaa taaacatgca aaacaattgc gcggcagtaa
    16081 aattcaaact attggcgtca ttttacctag cttaacaaat ccgtttttct cagcactgat
    16141 gcaaagtatt catgaccata aaccatctga tgttgattta tgctttttaa catctacagc
    16201 aactgatttg tatgacaata ttaaacattt aattgatcga ggtattgacg gattaattat
    16261 cgcacaatac atatcatccc cggacgccct aaataactat ctaaagaaac atcatgtacc
    16321 ttatgtcgta ctggatcaaa atgaccatca aggctataca gattttgttc ggacaaatga
    16381 atatcaaggt ggacaacttg cagcacaaca tttaatagaa ctcggtcaca accatatgat
    16441 aattgttgca ccatatgaca tgatggcgaa tatgtcgact cgtgtcgctg gatttgtcga
    16501 tactttgcgc gcgaatcaat tgccagaacc acaaatcgtc catactgaat tatctaagcg
    16561 cggtgggcta accattgttg atgacatcat ggttcaatct gccactgcaa tcttcgctat
    16621 taacgatgaa ctcgctattg gcattttacg aggactaatt gaacatggca tcagtatccc
    16681 gaaagatatc tcattaatag gttatgacga cattgattat gcagcgtacg tctcgccacc
    16741 tttaactact gtggcacaac ctataactga tattggcaaa acatctttaa ccttattact
    16801 tcaacgatta cagcacttag ataaatccat tgatatgatt gaattaccaa cgactttaaa
    16861 aattcgtgca acaactggct atcatctttc aaactaacta cgtatcttcc gaaatatact
    16921 catcattgtt aggcccttag cgttgcttta atgctgaggg tttttaatca taattatttc
    16981 actaagaaat taaaataata atgtatgaat ttttaaatat gatttaaacg ttttcagttt
    17041 ttatgaaaac gcatgcattt tgcaaataaa aatggtacga tggcattggt aaaacgtttt
    17101 actaaaaaca aatcgtgagg tgtataacat gagcattgtt gcattactta tcgggttagg
    17161 ccccttaatt ggctggggct tcttcccaac agtcgcttca aagtttggtg gtaaacctgt
    17221 acatcaaatt atcggtgcta ctgtaggtac gttaatcttc gctattatat tagccgtagt
    17281 cacatcaagt ggcttcccta ctggaaccaa tttgctattc gccttattat caggtgcagg
    17341 atggggattc ggacaaatca ttacatttaa agcgttcgaa ttaatcggct catctcgtgc
    17401 catgccagtc acaacagcat tccaattatt aggcgcatct ttatggggtg tctttgcatt
    17461 aggaaattgg ccaggcattg gtcataaaat cattggattt acagctttag tcgttattct
    17521 aattggtgca cgtatgacag tttggagtga acgcaaagaa gcaagtaacg ccaaaaattt
    17581 acgtcgtgca gtggtacttc tgttaattgg tgaatttgga tactggttat attcagctgc
    17641 accgcaagca acttctattg atggcctaac tgccttttta cctcaagcaa tgggtatggt
    17701 aattgttgca gtcatttatg gctttatgaa tatgaaatca gagaatccat tccgtaataa
    17761 aattacgtgg ttacaaatta tttcaggttt cttctttgca tttggtgcct taacatatct
    17821 tatttcagca caacctaata tgaatggttt agcaactgga tttattcttt ctcaaacatc
    17881 cgttgtgctt gctacattaa ctggtattta tttcttaaaa caacataaaa cttcaaaaga
    17941 aatggttatt acaattatcg gcttagtact cattttagta gccgcttctg ttacagtatt
    18001 tataaaataa ggagtgtaga tgtcatgaaa aaatcagctg ttttaaatga acatatttca
    18061 aaagcaatcg cgacaattgg tcattttgat ttattaacga ttaatgacgc tggcatgcca
    18121 attccaaatg atcatcgccg tatcgaccta gctgtcacaa aaaacttacc acgctttatt
    18181 gatgtcttag ctacagtgtt agaagaaatg gaaatccaaa aaatatactt agcagaagaa
    18241 ataaaagaac ataaccctac acaattgcaa caaattaaac aattgatttc atcggaaatc
    18301 gaaatcattt tcattcctca cgaagaaatg aaaagtaact tagctcaccc attaaataaa
    18361 ggtaatattc gtactggtga aacaacgccc tactctaata ttgcattaga atcgaatgtt
    18421 actttttaaa aattataact tgaaaggagc atacacatga ccaacaaagt tgttatttta
    18481 ggttcaacga atgtcgatca atttttaaca gttgaaagat atgcacaacc aggcgaaaca
    18541 ttacatgttg aagaagcaca aaaagcattc ggcggaggta aaggtgccaa ccaggctatt
    18601 gccactgcac gcatgcaagc agacacaaca tttattacta aaattggcac tgatggcgtt
    18661 gctgatttca tcttagaaga ttttaaagcg gctcatattg atacatcata tattatcaaa
    18721 acaactgaag caaaaacggg ccaagccttt atcactgtga atgcagaagg acaaaacacc
    18781 atctatgttt atggtggtgc gaatatgacg atgacacctg aagatgttat taacgcaaaa
    18841 gacgctataa tcaatgcaga ctttgtcgtt gcacaattag aagtacccat cccggctatt
    18901 atatctgcat ttgaaattgc caaggcacat ggtgtgacga cagtattaaa tcctgcacca
    18961 gcgaaagcat tacctaatga attattatca ttaatcgata ttattgtgcc aaacgaaaca
    19021 gaagccgaat tgttatctgg gattaaagta actaatgaac aatctatgaa agacaatgcc
    19081 aattactttt tatctttagg cattaagact gttttgatta cgctaggtaa gcaaggtaca
    19141 tattttgcta ctaaaaatca aagccaacac atcgaagctt ataaagtaaa tgcgattgat
    19201 acaactgctg caggcgacac atttattggt gcatttgtca gtcgcttaaa caagtcgcaa
    19261 gataacttag cagatgctat tgattttggt aataaagcga gctcactcac tgtacaaaaa
    19321 cacggcgcgc aagcatctat tcctctacta gaagaagtaa atcaagttta aatgaatcaa
    19381 acacagctat gatatgaagg tttagcatat aacatgcaac attcgtatat catggctgtg
    19441 cttttttatc tttataaaac atcatctatt agaaataatt ttccactaaa cctatgcttg
    19501 ttgactcatg tttagttata aatgaagtga caattttttg taatcttttt aacttccaaa
    19561 ttattgcata taaatatgct atattaatga taataattat caattaaaag gaggttatgc
    19621 tatgtctaaa gaagctggtc atacattttt agctaaatta ggaaaaactc gtctacgccc
    19681 cggtggtaaa gaagcaacag attggttaat acaacaaggg gcattttcac aagataaaca
    19741 agtgttagaa gtggcatgta atatgtgcac aacatctatt tatctagctc atacatatgg
    19801 ctgtcacatt caaggcgttg atataaataa gaaagcatta gaaaaagcac aggaaaatat
    19861 ttcagcagca ggtcttgaat catatattca agttcaacaa gcgaatgctg ttaaattgcc
    19921 ctttgatgac aatcaattcg atatcgtttt aaatgaagca atgttaacaa tgttacccat
    19981 cgccataaag gaaaaagcat tacgcgagta ctaccgagtc ttaaagcctg ggggtatctt
    20041 gttaacacat gatattgtca tcgttaatga atcacatgcc acacatgttg ttaaatcatt
    20101 atctgcagca attaatgtca atgtctcacc gcagacgaaa cttggctggt tagatttata
    20161 tcatcaagct ggttttaatc atgtgcatta tcatactggt ccaatgagtt taatgacacc
    20221 aaaaggttta atttatgacg aaggtattgt tggaactata aagattatca aaaatgcttt
    20281 aaaaaaagaa aatcgaccaa tgttttgtaa aatgtttaaa acgatgacta aattgcgtaa
    20341 agatatgaat tatattactt ttgtcgctaa aaaagaggac taaatataat gccactaact
    20401 gtactttgta tctatgtttg actgctactt taatttcttt gtgacactaa tcatctactt
    20461 aacaatatcg ttatcgttga ttagtaagtc atcaatttgg gttaaagact ttcataaaca
    20521 ctcaaacatt aacactatac ttagttagtg gcattatttt tttaaaaatt ttaacatcac
    20581 gggattggaa cagaaatgat attttcgcaa aatttattcc tgtccttccc caacttgcat
    20641 tacctgtaga atttcttttc gaaattctct gtgttggggc cccgccaact tgcattgcct
    20701 gtagaatttc ttttcgaatt tctctgtgtt ggggccccgc caacttgcat tacctgtaga
    20761 atttcttttc gaaattcttt gtgttggggg cccgccatta taacactgta ggtcctacta
    20821 tattaattta tgtctcgggc tctaacccta aaatacttat aatatacctt tataatttat
    20881 ctccatttga tgctatcact tgttgatacc aatagaacga atcttttttc aagcgttcca
    20941 tcgtgccatg accatcatta tctcgatcaa catatattaa accatagcgt ttcttcattt
    21001 caccggttgt aaatgaaaca atatcaatga ttccccacgg tgtataaccg attaaatcta
    21061 caccatcttg atcaactgct tctatcgctg ctgtaatatg tgcttttaaa tattcaatgc
    21121 gataatcatc atgaatatgt ccatctacca cttcatcaac tgcaccaaaa ccattttcca
    21181 caataaaaag tggtaactga taacgatcat ataacacatt caatgtatat cttaagccat
    21241 ctggatcaat cgcccaaccc caatcactcg ttgcgatatg cggattctcc acagaatgat
    21301 tcaaaccacc gttgacgatg ttgttttcaa ctgtagtatc aacatcatgt tttacagccg
    21361 tagacatgta ataactaaag ccaatataat caaccgtgcc ctgctgtaaa atactgtcgt
    21421 ccccttcttg ccatccaaca tcatatcctt ttcgtgccaa cattttttta gcatagcttg
    21481 gataataacc tctcacttgg acatccggga aaaagaaacg taagcgattc gcaatttgtg
    21541 cttccatcat atctttcgga tgacacgaat atggataaat gggtacatgt gaaatcattg
    21601 ttccaatctt aaacttcgga ttaatctctt taccaagacg aactgctaaa gcactggcta
    21661 aaagttcatg atgtgctact tgatacaaga cttcttcagg attatcattt tctgtcaatg
    21721 ctaccccaga attcgtccat aaaaagatag gatttgatgt gtccatctga ttattaattt
    21781 cattaaacgt catccaatat gtaactttat ctttatatct ttcaaataca acacgcgcaa
    21841 aatgcacaaa ataatcgaca acttctctat ttctaaatcc accataatgt ttcgctaaat
    21901 gaagtggcat ctcaaaatgt gataacgtca caacaggttc aataccttgt gcaattaatt
    21961 catcaaagat acgatcataa aaggcaagtc cttcttcatt tggcacatct tcatccccat
    22021 tcggaaagat acgtgtccac gcaatcgacg tacgtaaaca tttcaatccc atttctttaa
    22081 acaaggcaat atcttcctta taacgatgat aaaaatcaat accttcatga tttggataat
    22141 agtgattgag gtctatagat tctgtaatct gacgtgcttt gccatgtgca ccactcgtca
    22201 taacatcaat tacacttaac cctttaccac ctttttcata tccaccttca aattgatttg
    22261 cggcaagagc gccaccccac ataaaatttt gcggtaattt tgtcattatt acaacacact
    22321 cctagttttt aaatatttta aaaataacat cttcagtcgt aatgatttca ttcattgtca
    22381 gttctacttt tcctaaatcg gcagagttgc taataacgac aataacgtca gcattgtagc
    22441 cttgttgttg tatatattgc tggtcgaatt gcaacaacgt ttgccctgct tcaacatgat
    22501 cattttgctt tacaaagcac ttgaaccctt taccttccaa gtcaactgta ttcacgccaa
    22561 tatgaatgac tatgtccaca ccgtcttctg attgaatacc aactgcatgc ttagttggta
    22621 caatcataga tattaaacca ttgaacggtg cgattacttt ggattcttca tgagctttga
    22681 ttgctaagcc ttcacctacc attttctctc taaaaattga atctcttact tctttaagta
    22741 aaatacgacg accagcgatt ggtgctttca ctaaaattgg tgttgttact tttacttgag
    22801 gtgtataact tgtatcttgg ctattaatat tgtcagtatt ctcactctct tcgacattag
    22861 cattcttaat taatcgctgt aattgctgat acacttcatc gacatttcca tttaatttta
    22921 tgactaactg cgcatcattt tctgctacag atgtcacatc aactatttgt ttcacttcat
    22981 ttgctgtaga aggaattgta tgttgcatat gaattgtaat gcacttcgta tcatacgttg
    23041 catcaacaat gttttcgaca ccacctacag ctgtaagaat gtcttgggct tgttctttat
    23101 atttattgct cataaatatt accccctcaa cttgatagta gaatgaaaat gtatttactt
    23161 acctccaatt ataattgtac cggttcaatt tgtaaacgcc gatacaatta taatattttg
    23221 tgctataata attacagaca aagtgaaacg aggacagaat attgttaaag tatgaacata
    23281 ttgctaagca acttaatgcg tttatacatc aatctaattt caaacccggt gataaattgc
    23341 caaacgtgac gcaattaaaa gaacgttatc aagtaagtaa gagtactatc attaaagcat
    23401 taggcttatt ggaacaagat ggtttgatct atcaagcaca aggcagtggt atttatgtga
    23461 gaaatattgc agatgccaat cgtatcaacg tctttaagac taatggtttc tctaaaagtt
    23521 taggtgaaca tcgaatgaca agtaaggtac ttgtttttaa ggagatggca acgccaccta
    23581 aatctgtaca agatgaactc caattaaatg cagatgatac cgtctactat ttagagcgat
    23641 taagattcgt ggacgatgat gttttatgta tcgaatattc ttattatcat aaagaaatcg
    23701 tgaaatattt aaatgatgat attgctaagg gctctatctt cgattattta gaatcaaaca
    23761 tgaaacttcg tattggtttt tcagatattt tctttaatgt agataaactc acttcaagtg
    23821 aagcttcatt actacaattg tctacaggtg aaccatgttt acgttaccac cagacttttt
    23881 atacaatgac tggcaaaccc tttgattcgt ctgacatcgt atttcattat cgtcatgcac
    23941 agttttatat tcctagtaaa aagtaataaa tacataaaaa cgtctatatc ccagttataa
    24001 actggagtat agacgttttt ttacgataat aacaatggct caaattgcta ttatcttgct
    24061 taggtttttc gttttagaag aatattgcta caaagacagg cacaactgct acaacaacta
    24121 caccaactaa cactaaagct atacttgcca ttgattcttc tacaggtcct aattctttgg
    24181 ctggtgctac acctaatgtg tgaccacttg ttccaagtgc taatcctcgg gcaatagggt
    24241 tagtaattcg gaaaagcttc aagaatttat tacctagggc ataaataatg acaccattta
    24301 aaataactgc taatgatgtt aattctttta taccaccgat accagctgat actggtaacg
    24361 caatcgctgt agttgctgct tgaggtaaca ttgataaaat aacatcattg gcaaattgtg
    24421 ctaacttcgc aaaagttaaa ataattaata acgctacaac tgtaccgata ccaatacctc
    24481 ctatgatacg atgccaatgt ttaacaagca cttcacgctt tttatataac ggaatcgcaa
    24541 aacagattgt tgccggttct aagaagaagt aaataatgtc tccacctatt ttgtaagtct
    24601 tatacggaat gcctgttaaa tagaggaagg ccacaccaaa taccatactg acaaatagcg
    24661 gtgcgaataa gaagaaacga ttagtttttt caaataatat ggtcgctaag aaaaatggta
    24721 taacggataa cagtattccg aagtaaggtg tgtttagtgc taagtggtta atcatgagct
    24781 tgtgcctcct ctattttgat cttttttgtg actttgtcac ctttagatct cgaagtaact
    24841 ttcataataa tttgtgtgac atagccagta caaataagta atagtattgt tgagacgatt
    24901 attagtccaa tgattaaaaa tggtgcttgg ctaatgacac ctaaagagtt aacaactgag
    24961 ataccggctg gtacgaagag taagccaatg ttatttgtta gtgtcgttcc tactttttcg
    25021 acttcgccta acttaacagc accagtacat aataatacaa ataataatac taaaccgatt
    25081 actgatgcag gcataggaat tggcataaat gattcaatta ttttcgatac aaagagtact
    25141 aaagcaatta caatgacttg gtgaaaaaag tgtgctggtt ttgatgcgtc tttttgttgt
    25201 ttcacgacca ttgcctccta cgtttgattt aactaaagta tagatggctc acttcgattt
    25261 gcgtgatttt tagtccgaaa tacaaaatat cataggtaaa atgcataaaa aaaaggatta
    25321 ctgttaaagt aatcctatcg acgctttaaa atctttcata aatgaacgtc caacttgcat
    25381 cttgacacca tttgtcaata ttaccatata agtgtagtta aaccattgtt gcacttcttt
    25441 aatgtgtttc gtgttaataa tatatgaacg atgaatacgt ataaaataag tgggattcaa
    25501 tcgtttttca taacgattca atggctctgt tgtttcgtat ttatgattcg ttgtatgtat
    25561 ggttgtaata ccattatgtg tgccaatccc aataatattt tgttgcttta acatgtgaat
    25621 tttatcgtca atttcaacag gtaagctttg atcaaaattc gccgacatat cattcgcaat
    25681 tgcacttgcg ttattatcat ctttggcttt agtcgcacgc actttattga ctgcttgttc
    25741 aatacgtttt tgaccaaacg gtttcaaaat atagtctgtc gcatttaatt caaatgcctg
    25801 tactgcgtat tggtcatgtg cagttgcaaa aataatcgca ggtggctctt tcatcttttg
    25861 aatcttagct cctaattcga tcccattttc atccattaaa ttgacatcta aaaatataat
    25921 gtcatattga ttgatcagta gtgcttccaa tgtttctttt acattttctg cctcattaat
    25981 ttcttcaaaa ccaccaattt catttaataa atatgttaat tcattacgtg ctaatggctc
    26041 atcatctatg attaatgctt tcatatttat tcctcctctt gtctttcata aggaagtaca
    26101 caccaaaaag tggtaccgct cgatgtcgat tcaaattgta atgctgcgga ttttccaaat
    26161 aatcctttta ggcgtaagtt taaattttct aaagcactac cagttccaga ttctgattct
    26221 acagatgttt ctcccaacaa atgcatttta tctttagaaa taccctgacc attatcttgt
    26281 acaataatac gtacatgtgt tgcagtttct ttaatcactg acacgtcaat atcgttacct
    26341 tgctttcgat tcgtaaacgc atgtttgatg gcattttcaa ctaaaatttg aattaaaaat
    26401 ggtggtacaa gcacatcgcg atatttgtct tcaacattaa tattgatatt aaatcttcct
    26461 ggataacgtg cttgttcgag tgataagtat gcacgcactt gacttaactc tttatctaaa
    26521 gtaatcgtat gttgctttga gccttgtaaa ttcgctctga aaaaataact caattctaat
    26581 agtaactctc gtgccttttc gctatttatt ctaactaaag ctgaaatcgt gttaattgaa
    26641 ttgaagaaaa aatgtggact cacttgtgcc tgtaatgact taatctcagc atctttcaat
    26701 aacttacttt gcgtttcggc ttcaccaagt tcaatttggc tactaaaaat atttgccaat
    26761 ccttctgcaa gttgacgttc cacaaaagtt aaatcattag ggtttgtaaa atacatcttc
    26821 aatgtaccga cgatagaacc atgcatctca agtggtatca cgatagctgc tctaagcggg
    26881 caattcggat gactacaacc aatctcttct ttagtatgca cttctttcaa ctttcctgat
    26941 ttcaatacat ctttagacag acttgttaat atttcatttg ttggtatgtg atgatcacta
    27001 cctgcaccta catgcgataa gatttcattt ttgcttgtaa ttgctacggc agatactttc
    27061 attaaatttt taataatcat cgcaatttgc tgtgccgatt ctctattcaa tccttcttta
    27121 aaatacggca atgtctggtt catcaattgc agtacgtcat gtgtttgaac agccttcatt
    27181 tgctcttctt gctttaatgt tgaaatgata atagacataa aaatcgccgt accaacgcta
    27241 ttaacaataa tcattggtag tgcaattaat gatatgaggt caaccgcata tgctttgtcg
    27301 tgggaaaatg ttaaaatgct caacatttga atcatttcca taacaattcc aatcatggca
    27361 cttttcgcaa tactcgggta acgcttgcgt ctttgagctt gtaagccaaa ataaccagca
    27421 attataccga taaatataga tgagataaga taaacttgtg catccgcccc acccatatac
    27481 actctgaaaa tacctgaaat aacgccaaca aatagaccta caaaagggcc accaactaat
    27541 cctgcgacac ctatcgttaa tacacgtgtg ttagctaaag atacatcatc atctaaacgg
    27601 aagtacacac ttcctgacaa actatgttga tgatcgatga cgataccagt taaattagac
    27661 attaaggcaa acaaactgaa aataatacat aattgccaac gtgctttcca tgtacgtcga
    27721 cgattcatta agtttttaaa atatggaata ttcatcaaca cataggccaa aataataatt
    27781 aaacctacac gctcaagtaa taacattgtt agcgatagca cgatagcacc tcagtgaatt
    27841 ataattatgt ttattttatc ataatagtgc atgtaaaatt catgaataaa ttattaaaaa
    27901 aacacgctac tatttaatta tctataccat taaattttca tatcaatttt tatgctaagt
    27961 tgaccatttt tcttttcaaa taatgctgtt catatcacta aatttctgtt aagtatagcg
    28021 aaaaactgct gacattactt tgccaacagt ttctaatcgc gttatttatg atactttttt
    28081 aaataaaaca tgattctcta aatgaacatg ctcatgtgtt aacacttcaa gtgcttttaa
    28141 tctctgataa acgagtcgcc acgtaccaca tgcctctatc ggtggttcat agctagatgt
    28201 taaatcgctc attttcacta acaattgtcc cgttgcaatg tgatcagata ctaaatcatc
    28261 aattactgta ttaatatcgt ttactacttc accttgttca tatttaatta gttttggaaa
    28321 atcaacatca tcttcttttt gcatatgctc taacatgcca cttttaaatg tatcatatgt
    28381 ttcttttaac tcgactaaat atggatggtt aggtccatgt actttcgata atttcgtcac
    28441 ataaggtgtt aaatttttaa attcttctct aagaggttca tgatatgctg cttgaatata
    28501 ttgaataagt gacgaaacat ttaaaaattt agggttaagc gaacctggtg tattcgtttg
    28561 ttcaacgtca ttgagacgct gtaataattc gttcaaatct acatttttct tttctaagga
    28621 tgctgcttct atacttactt gtccaccgca acaaaagtct atacctacgc ttctaaaaat
    28681 atctgctgct ttcggataat ctattactat atctgctact atgtcatttt tatttatcat
    28741 tatagacgac ctcctcattt tcagtgtata caatttaatg tatatgaaaa tgaaaatcag
    28801 ggaaatgtca taatcatttc ataaatagca aaataaaacc ctcaaattat gttagttcac
    28861 atagatttga gggcatttat tatttatttt agcgagtaag tcatatgtgc agtgtttaac
    28921 ttaacaatat ttttgaagtc tcgcttctta atatctttac taagtaagat ttccacttcg
    28981 ttttctgacg tttggcttaa cattcccata atcatgtcgt cttttagcac gacactagcc
    29041 ataccttctt caaatacata accacgatcc agaccagtta aaatgatttt gtttttacct
    29101 tttaacttca ttgagattga atccgttaat gtaatagctg taaagtataa cgaaatgtta
    29161 ttaaagtctt ttgtgaaata cggtgttaat ctataaaaat cattatttaa atgaattaat
    29221 gcacttgttt ctgcagtata tgcatattta ttacgttgat taccaacacg cacttcaaat
    29281 acttccgtac ctatttggac ttctaagaaa acatcccaaa ttttttcttt aggtaaatac
    29341 gctttaatat cttctaacat aatgttaaaa cgatattgtt tattcgcatt gacacttaaa
    29401 ggtacataca ttgtgtgctt cttgtttcgt gaatgtaatt taagtctgac atcataatgt
    29461 ccttcgccaa tcataaattc atttaacgtt agctctgtaa caattttatg attatcaaat
    29521 ttaaatgctg tcattttcac ttttggctta gcgatatcaa tgccttcaaa gtatggttcg
    29581 ccttcattga attgaatgtt taatttacca tctacaatat caaaacggta gtattgacct
    29641 tgacggtaac tttcttctac agttctatag ttgtctatat ctttcgctct cgcgtagtgc
    29701 aacaatggtc gtaatttact catcaccaat gcatctacac gttctggaac tgcttgtata
    29761 aagtctccta gagcattaat ccattgtggt tgctcttcaa gtttaacttt aagtgagaag
    29821 ccattcgtac gagaaaaact aaaatgacga tttaaaaatt ctgctaagat ttgatcttta
    29881 tgagcttctt ctaaatctgc atttaatatt tctacagcaa tcaatctcat gacttcgtaa
    29941 aagtcttcag gtgaaacata cgcactactc atatgttcac cttcacgctt tgtagcataa
    30001 taatacgctt tatcacttaa cacactgatt cgatttgcat tcaaatatgc tttcattgta
    30061 aataattgat cttctgcact ctttaattct tctggaaaat aaatgtcatt atcttttagt
    30121 aatgctgttc tatagatttt agtcgggctt aaagtataga taattcttga atttaacaaa
    30181 gtaacttcag gtgctgtttc tttaaacata gattgtggta caccacgacc attaacacct
    30241 ttcattttaa tcaataagac atctgagtga tgttcatcaa taaatgctgc tgcatccttt
    30301 aaagtctctt tgtttatata gtcatcggag tccacaaata atacaaattc accttctgct
    30361 tgttttaacg ccacatttct aggtttacct ggaccaccag aatttgtttc gagttgactt
    30421 actttcaagt tcaatttatt gcgatacttt tcaactattt gtaacgtttg atctgttgaa
    30481 cagtcatcaa ctacaaccac ttcaaattca gttttcggaa aatcttgttt cgcaaggcta
    30541 ttaagtaatt ctgttatata cttttctgaa ttgtatgttg gaactattac tgaaaatttc
    30601 atcattatac ctctcccact ttgactacta tataaactta gctaccaaat aaatttctga
    30661 ctaaacgctc acttgatcgg ccatcttgat atttaaaatg tttatctaag aatggaatga
    30721 ctttttctcc ttcataatct tcattgtcca aggcgtccat taatgcgtca aatgattgca
    30781 caattttacc tggaacaaat gattcatatg gttcataaaa atcacgcgtc gtaatataat
    30841 cttctaaatc aaatgcatag aaaatcattg gctttttaaa tactgcatat tcatatatta
    30901 aagatgaata gtcactaatt aataaatctg ttatgaacag tatatcatta acttctctaa
    30961 agtcagaaac gtcaacaaaa tattgtttat gtttgtctgc aatattaagt ctatttttca
    31021 caaatggatg cattttaaat aatacaaccg cgttattttt ttcgcaatat cttgctaaac
    31081 gttcgaaatc aattttgaaa aatgggtaat gtgctgtacc atgaccacta cctctaaatg
    31141 ttggtgcgaa aagaatgact ttcttacctt taataattgg taattcatct tccatctctt
    31201 gtttgatctg tgtcgcataa gcttcatcaa atagtacatc agtacgtgga acacctgtag
    31261 gcactacatt tttctcttta ataccaaatg cttcagcgta gaatggaata tcggtttcag
    31321 atgatacata agcttttgta tagctacgat gatttaatga atcaataaat ggtccaccct
    31381 ttttaccagt acgactaaag ccaactgttt taaaggcacc aacggcatgc catacttgaa
    31441 taacttcttg agaacgtcta aaacgcactg tataaatcaa tgggtgaaag tcatcaacaa
    31501 agatgtagtc tgccttccca agtaaatatg gcaatctaaa cttgtcgatg atgccacgtc
    31561 tatctgtaat attcgcttta aaaacagtgt gaatatcata ctttttatct aaattttgac
    31621 gtaacatttc gttatagatg tattcaaagt ttccagacat cgttggtcta gagtctgatg
    31681 tgaacaacac cgtattccct tttttcaagt ggaaaaattt cgtcgtatta aatatcgctt
    31741 taaaaataaa ttgtcttgta ttaaatgatt gtttgcggaa atacttacgt aattctttat
    31801 atttacgaac gatataaata cttttaactt ccggagtcgt tacaacaaca tcaaggacaa
    31861 attcattaac atcgctagaa atttcaggtg taacagtata aaccgttttc ttcgaaatgc
    31921 cgccttttct aaattctttt aggtaagtct gcaataagaa attgatttta ccattttgtg
    31981 tttctaattc gttgtattct tcttcttgtt ctggctttag attttgatat gcatcattaa
    32041 tcacatctgg gtttaactgt gcaatataat caagttcttg ctcattcact aataagtact
    32101 tatcttcagg taagtaataa ccattatcta agatagctac attgaaacga caaacgaatt
    32161 gattcccatc tattttgaca tcattcgcct tcattgtacg tgtctcagtt aaatttctta
    32221 atacaaaatt actatcttct aaatctaggt tttcactatg tccttcaacg aataactgaa
    32281 cacgttccca atagatttta tctatatata tcttactttt aaccaacgtt aattcatcct
    32341 tttctattta cataatccat tttaatactg ttttacccca agatgtagac aggtctgctt
    32401 caaaagcttc tgtaagatca ttaattgttg caatttcata ttcttgacct tttaacaacg
    32461 ctaatttatc tacaatatct gggtattgaa tgtataagtc tacaacatct tggaaatctt
    32521 ttgaaccact tcgactacta ccaatcaacg ttagtccttt ttccaatact agacgtgtat
    32581 taacttctac tgggaactca cttacaccta acagtgcaat gcttccttct ggtgaaatat
    32641 aatcaatcat ttgatttatt gctgattggc taccacgccc accaacgcac tcaaatgcat
    32701 gatcaaatgt taagccttca ggtattttat taataaagaa gacatcatca acaaatgaga
    32761 agtgactcaa tttataatct gttttaccaa agacatatat tttagactct ggatataatt
    32821 tacgtaataa aatggctgta atgtaaccta agttaccatc accccaaata ccaaatgtat
    32881 ttttatttga aatagatttc ttttcaaaac gacgaatagc atgcaaactt actgttacaa
    32941 gctctgtata tgaaataata cttaaatcaa tatcatcagg tagtggtaca gctctatcat
    33001 gatttagcaa cacaaaatct tgcataaacc catcatgtcc acttgatctg aagtagctcg
    33061 attttaaata gttttcagca atgacatcgt ctttttctgt cggcgtattc ggtaccataa
    33121 ctacttttgt acctttatta aacacacctt tactgtcaaa tacgacctca ccaacacctt
    33181 catgaattaa agacattggc aatttctgag ataagacatt ctcatcacgg ctaccagtat
    33241 aatatctttg atcggcagca caaattgaca tatataaagg acgtacaatg acatagtcac
    33301 tgtaaatatc tacgttgtta tacgtaactt caaattgtct aggtgcaact aattgatata
    33361 cttgattaat catcggcaat accacctcga ataatagcat tcgctacttt taaatcgtaa
    33421 ggtgttgtta ctttaatgtt atataactca ccttttacaa gtcgaaccgg tttgtttgtt
    33481 tctacaataa tcttacaagc atcagataaa atactctttt gctcatcact caactgtgca
    33541 tagctttctt ttaataaatt aatattaaac gattgaggtg tttgaccttg gtacatttca
    33601 ttacgcactg gaattgcatc aatcgtttga ttatctttag atgtaacaat cgtatctata
    33661 gcatcaatca ctgtatctac tgcaccgtac tctaaagcag cttgaatatt ttctttaata
    33721 atacgatgcg ttaaaaatgg tctaactgca tcatgtgtca caatgacatc gtcatcgtta
    33781 ataccatttg ttgattcaat atgtttaacg atattcataa ttgtatcgtt acgatcgcta
    33841 ccaccttgaa tgacttcaat tctttcatca gaaattttga attttctaag tgtatctttc
    33901 gtatgcgtca tccattgttg tggcgtcgcg ataataattt tttcaaaatc attaattaaa
    33961 ataaattttt ctaatgtatg gattaaaatc ggtttgttgt ctaaatctaa aaattgttta
    34021 ggtaaaggta cgttacccat tcttgagcct atacctccag ctagaatacc agcgtatttc
    34081 ataaaatact tcctccattc aactatatct atatttaatt atttaaattt cgttgcattt
    34141 tccaattgaa aactcatttt aaaatcaaaa ctctaaatgt ctgtgtatta cttaaaatta
    34201 tacatatttt gcttatattt tagcatattt tgtttaaacc tatattacat tatatcagac
    34261 gttttcatac acaaataata acatacaagc aaacatttcg tttattattt atatcactta
    34321 actaattaat ttataatttt ttattgtttt taagttatca cttaaaaatc gtttggcaaa
    34381 ttcgttgtga cgcttgtcca tcttctaatg aacagaattt ttgataaaat accgttcgtg
    34441 cttcaatata ctcatttgca gtctcatcga tttgttttaa tgcatcaatg agtgctgttt
    34501 gattttcaac aattggacct ggcaactctt ttttataatc catgtaaaaa cctctaagct
    34561 catcgccata tttatctaag tcatatgcat agaaaatttg cggacgcttt aatacaccga
    34621 agtcgaacat gacagatgag tagtcggtaa ctaacgcatc gctgattaag tataaatccg
    34681 aaatgtcttc ataatctgaa acgtctttca caaaatcatc atgttcatca atacgtgtca
    34741 caactaaata atgcatgcgt aataaaataa cataatcatc atccagcgct tgacgcaaag
    34801 cttctatatc aaagttaaca ttaaattgat atgaaccttc tcgaatcgct tcatcgtcac
    34861 gccaagttgg cgcgtacata atcacttttt tatctaatgg aatatttaat cttgtcttaa
    34921 taccattaat atattcagta tcattgcgtt tatgtgataa tttatcattt cttggataac
    34981 ctgtttccaa aatcttatct cgactaacat gaaatgcatg ttgaaatatc gatgtcgaat
    35041 atggattagg tgacactaga taatcccacc gttggctttc ttttttaaag ccatcttggt
    35101 aattttgagt atttgttcct agcattttaa cgttactaat atccaaacca atctttttta
    35161 atggcgtgcc atgccatgtt tgtaagtacg tcgttcgcgg tgatttatat aaccaatctg
    35221 gtgtacgtgt gttaatcatc cacgctttcg ctcttggcat cgctaaaaac catttcattg
    35281 aaaactttgt aacatatggt acattgtact gttggaatat gtgttcatat ccttttttca
    35341 caccccatat taattgggca tcgctatgtt cagttaagta ttcatataat gctttggggt
    35401 tgtcgctgta ttgtttacca tgaaagcttt caaaataaat tagattcttg tttggcaatt
    35461 ttgatagtaa tttaaaagtc gtatatatac tatgttctat caatttttta attgtatttt
    35521 taatcatgtc gtacctccga cgtgtttttg taattatatt aatatgtatg agcaagctca
    35581 ttgtaaccat gcctattata gcatttcatc ataaaataca tttaaccatt acacttgtcg
    35641 ttaattatca tacgaaatac atgattaatg taccacttta acataacaaa aaatcgttat
    35701 ccattcataa cgtatgtgtt tacacattta tgaattagat aacgattgga tcgattattt
    35761 tattttacaa aatgacaatt cagttggaag gtgattgctt ttgattgaat cgccttatgc
    35821 atgaaaaatc aaaaggttat tctcattgta tagtcctgct tctcatcatg acatgttgct
    35881 cacttcattg tcagaaccct tcttgaaaac tatgccttat gactcatttg catggcaagt
    35941 aatatatgcc aacattagcg tctaaacaaa tctttgacta aacgttcact tgagcgacca
    36001 tcttgatatt taaaatgttt atctaagaat ggtacaactt tttcaacctc ataatcttca
    36061 gtgtccaaag catccattaa tgcatcaaag gattgtacaa ttttacctgg aacaaatgat
    36121 tcatatggtt catagaaatc acgcgtcgta atgtaatctt ctaagtcaaa tgcatagaaa
    36181 atcatcggct ttttaaatac tgcatattca tatattaaag atgaataatc actaatcaac
    36241 aagtctgtaa caaagagaat atcgttaact tcacgatgat ctgacacatc gataaagtat
    36301 tgtctatgtt cacgtgaaat attaagtcta ttttttacga acggatgcat tttgaataac
    36361 acaactgcat tatgcttctc gcagtatctt gctaaacgtt caaaatcaat tttaaaaaat
    36421 ggataatgtg ccgtaccgtg accattacct ctaaatgtcg gtgcgaatag aataactttc
    36481 ttacctttta taattggcaa ttcatcttcc atctcttgtt taatttgtgt tgcataagct
    36541 tcatcaaata gtacatcagt acgtggtaca cctgttggta caacattttc ttctctaatt
    36601 ccaaatgctt cagcataaaa tggaatatcg gtttctgatg aaacatatgc tttcgtgtaa
    36661 ctacgatggt ttaatgaatc gataaacgga ccaccttttt tacctgtacg actaaagcca
    36721 actgttttaa aggcaccaac agcatgccac acttgaataa tttcttgtga tggtctaaag
    36781 cgaaccgtat aaattaatgg atggaaatca tcaacaaaaa tataatcggc cttaccaagt
    36841 aaatatggca atctaaactt gtctctccat ttgcgtctat ccgtaatatt cgccttaaat
    36901 accgttttaa tatcataatc aaaatctact ttttggcgta gtaactcatc atatacatac
    36961 ttgaaattcc ctgataaatt cggacgcgaa tctgatgtga ataatattgt tttgcttctt
    37021 ttaatatgta gtaactttgt aatattaaaa atagctttaa ataagaaact tctactttca
    37081 aatgaagctt tatgaccttg tttatgaagc cagtgtgcac ttgtcgcaat gacccctgat
    37141 ttctcttgag gtaaggtgat ttcaatatca aatacaaatt cgttaacgtc acttgctatt
    37201 tccggagtaa tggtatagac cgtatgttgt gatacgccac ctttacggaa aactttagca
    37261 tcatacgcta ataaatagtt cacttttcca ttttgtgtag tcagctcatt gtattcttca
    37321 atttgctctt catttaatgc cgcataagct tgatcaataa tatttggatt aagttgtcca
    37381 atatactcta actggtcatg ataaacaaat aaatatttat ccattggtaa ataataccca
    37441 tcgtctaata ttgcgacgtt gaatctacat ataaatgtat taccgtctat tttcatttca
    37501 tttgcttcta atgtttttgt ttcggttaaa ttcctcagaa caaattgtcc tgatgttaaa
    37561 tcgacacctt cactatgtcc ttcaatatat aactgaacac gttcccagta tatgttatca
    37621 atatgtattg cttgtttcgt ttttgtcatt gttattcccc catcggttta ttaaatcgtc
    37681 catttcaata ctgtttttcc ccaagatgtc gataaatcca tttcaaacgc ttggacgata
    37741 tcttgcatcg tacatacatt aatttcatgt ccttttaata atgctaactt ttcaactatg
    37801 tctgggtact tacgatataa atcaacaact tgctcaaaat ctttagagcc gcttcgacta
    37861 ctaccaatca acgttaatcc tttttcaagt actaatcgtg tattcacttc cacgggtaat
    37921 tcacttacgc ctaacaaagc aatactgcct tctggtgaaa tatgttcaac tatttgttga
    37981 agtgcaactt gacttccttt acctccaaca cattcaaatg catgatcaat tttaagatca
    38041 tctggtattt gatttactgt aaagatgtca tctacaaatg aaaaatgact taatttatag
    38101 tctgtcttac caaatacata aattttagct tctgggtaca acttacgtag caaaatagca
    38161 gtaatataac ctaagttacc atcaccccaa ataccaaagc tgtttttcaa aggtatagat
    38221 ttacgttcaa atcgttgtat agcatgataa cttactgaca ctaactctgt gtatgaaatc
    38281 gtactcaaat caatgtcatt aggcagcgga acgatacgat catgtgccat cacaacgtag
    38341 tcttgcataa aaccatcata accactagat ctaaaataac tagaggctaa gtaattctcc
    38401 gcgataatat gatgttgctc tgtaggtgta ttcggcacca ttactacttt cgtacctttt
    38461 tcaaatactc ctttactatc gaatacaact tcaccaacag cttcatgaac taatgacatt
    38521 ggcaattttt tgcgcagtac attttcatct cttcgacctg tgtaatacct ttgatcagct
    38581 gcacaaatag acaagtataa aggtcttacg atgacatgat taccataaat atcaacatta
    38641 ttatatgtga cgtcgaactg tctcggtgca acgagttgat atacttgatt aatcatcggc
    38701 aatatcacct tgaataatgg catttgctac ttttaaatca tacggtgttg tcactttaat
    38761 gttgtatagt tctccacgta ccaatttaac tgcatgtcca gattcgacaa ttattttaca
    38821 tgcatctgat aagatttctt tttgttcact acttaaggcg cgataactat cttgtaataa
    38881 tttaatatta aatgattgtg gtgtttggcc ttgatacatt tcattcctta cagggatact
    38941 gtgtatgttc tgtttatctt tagacattac aatcgtatca attgcttcaa tgactgtatc
    39001 tactgcacca tattttgctg ctacttcaat gttctcttta ataatacgtt gagttaaaaa
    39061 tggtcttacg gcatcatgag ttacaatcac atcatcatta ttaattccat ttacattgcg
    39121 aatatggtcg ataatgttca taattgtttc gtttcgatcc gtaccacctg caactacttt
    39181 gacacgttga tctgtaatgt tatatttttt taaaatatcc tgtgtatggg aaatccactg
    39241 tgctggcgtt gcgataataa tctcattaaa ttcactcact aaaatgaact tctcaattgt
    39301 atggattaaa atcggtttat tatcaatatc taaaaattgt tttggtaatg gcacgttccc
    39361 cattctcgaa ccaatacctc ctgctaaaat acctgcataa atcatgttgt cctccattct
    39421 gtcattacat catttccatt tatacattac tgacctatgc ccgcacataa gcctaaccta
    39481 ttgctcactt gcctctttta ttaatccaaa gatagttgtc acaatagtgt gataattttt
    39541 tataaaaatg tatttttgta actgaccatt ctaagttgtt ttgccatgca gttaatcatt
    39601 aactctgacg atattaaatt gttaaaggta ttaatgttta ctctttttca aattcattat
    39661 tactgccatc attttaccat atattataat aaatttatct tattaagtgg ctgtacttga
    39721 ttttcacttt aaaaattatc aaatattgcc atctcatttt aagtatacaa aatgcaaaac
    39781 aaccgattca caagcatatt tcacacaagt aaaccggcta tttatcaacg tatattcgaa
    39841 gatgaattat ttcgatagta tctgtagacc agacggcatt cgcactttca tagctataac
    39901 tataccagcg ttttcgtcct caaaggtgca tactaataaa tcgtaaacat gactttatca
    39961 aatcgttctt tcttgttaac taatttatca aatgtctccg ggcctttttc taacggtaaa
    40021 aaatgagaaa taataggctt tacattaata tctttcgtct tcatataatg taaggttgcc
    40081 gtccactctt tgcccggaaa attactggac aaacagttcc aagagccaca tactgtcaac
    40141 tcgttacgca gaattttttc aaaatgaacg cgatcaatct caatatcatc atatggtatt
    40201 ccgagtaata ccacctcgcc acctttttta ggtagcgtca atatttgacc aatcgtaact
    40261 ttagcacctg atgattctat agctaaatcg atttgattgg cgtaatgatt ttcgatgaat
    40321 ttctcaagat tttcttcttt tgaattgatt gtttgatgtg cgcccaatga tgttgcaata
    40381 tctagtttat gcgcatctat atctatagcg atgatatgtg cagcaccaaa tattcgtgcc
    40441 cattgaatag ctaacaaacc tatactgcca caccccatta ctgcaacagt cataccaggt
    40501 tgtatattcg atttataaaa cccatgcgca acaacggctg atggctcaac cattgctgct
    40561 tcaatgtaat caacattgtc tggaaccttt aaaacatttt gcgctggcaa tttgacatat
    40621 tccgcgaacg atccaggttc atatgagcca atgacgaata acttttcaca tcgtgcatat
    40681 tcacctttca aacaatactc gcattgataa caaggtattg ctgggcaacc tgtcactttg
    40741 tcgcccacat taacatgcgt aacatcactt ccaatggcat ctactacacc tgaaaattca
    40801 tgaccaaatg gcataccttt aatgtatggc cccatttttt tgtatcgtga cgtgtctgaa
    40861 ccacatatgc cagtcgctcg tactttaaca ataacgtcat tcgcactttc aatgactggc
    40921 ttttcattat cctcataccg taaatcttct acgccatata atttcaatgc tttcacttgt
    40981 aaatcacctc aaatttgatt taattcacaa cttttttctt tttaaaaata cctgtcgcaa
    41041 aataacctgc aatgacgatg gaattactta cgagtaaatg ttccatataa aaatcagtga
    41101 tttgtcttaa tggcccaagc ataaaagtta gcattgattc taccatatta attctctcct
    41161 tcattttcat ctaaatcgag cggcttaagt aatgctttaa taccttcgcc agattttaaa
    41221 tgttgatacg cctcgtccca tttcgaaata tcatatattt ttgtcaccaa agcttcagca
    41281 tttactaaac catccgccat aagttgcaat gaaggttccc aatctgctgg cttttgactt
    41341 ctactaccaa caactgttat ttctttttga atcacttttt ccatatcaaa tggaatttca
    41401 gcatccttaa aaatacctat ttgactgtag aaaccttttt tgcgtataat atctaaacct
    41461 tgtcgtgctg ctggaactgc acctgaacat tcaacaacaa catctgcacc gtaaccgtct
    41521 gtaattccat tgatatacgt ttttaagtct gtttgttgta aattgactac ataatccatg
    41581 tgcaatgctt ctgctttatc taatctgact ttgtcattgt ccaatccagt taccacaaca
    41641 gttgcgcctt tacttttcaa cacttgtgct acaagtaatc cgattggccc aggtcccatt
    41701 acaactgcta catcgccaga gttcacttga atcttagaaa cgccatgatg tgcacatgct
    41761 aatggttctg tcatagctgc agactgatac gatacttcgt ctggaatatg atgcaaactt
    41821 tcttcacgtg caatgacata attagtaaat gcgccatcaa cttgtgttcc aatacctttt
    41881 cgatggttgc ataaattata gtcttttgat ttacagtatt cacactcatt acaaacatag
    41941 aatgtagttt cagaagtgac acggtcacca actttaaaat ctttaacgtc tgctccaact
    42001 tcaacgattt caccagaaaa ttcatgacct aatgtcactg gaaaattaac tttataatgc
    42061 ccttcataag tatgaatgtc tgtgccacaa attcctgcat aatgtacttt aatctttact
    42121 ttatcatcta gcggtgttgc aacttcttta tcaagaagtt ctaagttgcc atgtccttct
    42181 cttgttttta ctaaagcttt caccacaaac acctcgattt ttaattgaat agactaaata
    42241 gtttaaagat aagatagtta acgataatac caccttgatc aatacttgaa atttcagatg
    42301 aaccttttgg catttgtaca ttcgtaactt tcgccatatc tgtgaaaatg ggtgctacgt
    42361 ctgttgcaat atataatgaa attgcaatca taatcgtacc cacaatgaca gaatgaataa
    42421 tgtttcctct tgctgcacca acaataaacg cgacaacaaa tggtatagtt gctaagtcac
    42481 caaaaggtag tacttggttt cctggtaaaa taacggctaa taaaacagtg ataggtacta
    42541 aaattaatgc tgtcgaaata accgctggat gacctaatgc tacagccgca tccaatccaa
    42601 tataaatttc acgttcgcca aaacgtttat ttagccatgt tcttgcagac tctgaaactg
    42661 gcattaaacc ttccattaag atttttacca ttctaggcat taataccatt actgcagcca
    42721 ttgacattcc taaattaatg atgtctccag gtttgtaacc tgctaacaca ccaataccta
    42781 aacctaaaat taagccgaca aatatagact ctccaaatgc gccaaaacgt ttttgaattg
    42841 tttcaggatc agcatctaac ttattcagac cgggtacttt ttgtaacaat ttaactaagt
    42901 aaatacctgg tgcataagaa atcgtgcttc ctgtcgcaat cgatacacct ggtaaatcaa
    42961 agaactcact catcatcggt gctgtccaat ctgctacttt caaacagata acttggaaaa
    43021 taactgctgc taataacgct tgccaaatac tgcctgatac ggcataaacc attgctgctg
    43081 taaacgtata atgccaaaaa ttccaaatat ctacattcat cgtctttgtc actttagtta
    43141 ctagcaatac aacgttaact atgattccga gtggaataat aaatgctgcg acagatgatg
    43201 cccaagcgat agatgatgtt gctggccaac ctacatcaat cacattcaga ctgacgccta
    43261 aatttttaac catcgcttgt gctgctggcc ctaaattttt aactaataaa tcgatgacta
    43321 agaaaatccc tacaaaagcc acacctattg ttaaaccaga cctaaatgcc gctccaattt
    43381 tctgcctaaa gaataggcca agcaagaata tgacaaccgg taaaataaca gttgcaccta
    43441 aatctaaaaa tccccttaca aaatcagtga agtaactcat atttaaaccc tccctgttat
    43501 atatgcattg tcacgatact ttccgattgt gattacattt gacgttacgg tcatttcaac
    43561 gacaaccctt gctacattcg actgcagtcc ctttgaatta cagtcactgc gtttctatgt
    43621 catcaacaat catttgtcgt gatagtcatt tatatgcaat ttgcatatat ttatatgtta
    43681 ttgacccacg ttacatatca attccgttat ttttgtaact ctgttaagat ttgttgtttt
    43741 gtttcttcaa taccaatacc agttaagaaa ttacgtgcgt ttataactgg gaatttatat
    43801 tctttctttg tcattgcagt tgtaactaat aaatctgcag tgtcttcata aggtccaact
    43861 tctgtaattt tgatttgttt aatatctact ttaatattgt gttcctttgc catttcctca
    43921 attgcattat ttactactgt tgacgttgca atacctgcac cacacgctac taatacttgt
    43981 ttcattttca attcctccaa ttaattttta gttatattcc aaataatcat tgattagtgt
    44041 tgctaaaatc gtttcatctt tcgttcgcag aatctgctcc aatttttctt cactttgaaa
    44101 aatttgcatc aactgttgta acaacttaag ttgatcatct actttatcca tcgctaacat
    44161 aaaaacgatt ttcacttctg tctgttgatc aagtgttccc atttcaataa acggcacctc
    44221 tttttctaga acagccacac ctatcgttct atggttaata tgttcgacat ctgtatgcgg
    44281 tatagcgacc gaacatagat gtgttggtaa accagtagca aattcttttt ctctgtcgat
    44341 gactgcatct ttaaacgttg acttcacgaa cccattttga aataacacat ctgacatttg
    44401 tgacaatacg gattctttat cagttgccga caaattgagc attatatttt ctttatgcac
    44461 taattgctgt cccatccatt ttccctcgct tctttatttg aataattttt taaaatctca
    44521 tttacatcag aatttttgcg actttgtatg atgcgcttaa ttgcgtcatt gtcttgcgcc
    44581 acatctctca attgtagtaa cgctcttaag tgtgtcactt tatcaacagc agcaataggt
    44641 acaataatat ggattgctgt gccatctgac atgtatattg gttcttgtaa tatcaacata
    44701 ctcatcgctg ttttatgtac atgcttttca gagtatgcat gtggaatagc aatattttgc
    44761 atgataacca tatacgaatc atcaaatacc tgttgcatct catgaatata tttaatatca
    44821 ataaaatgat tagcaactaa cacatcactt gctttagcaa tagcttcatc aatattttca
    44881 acatgatgca ttcttttcac gtgccttgcc ggtatcaagt cagctaaatc taatgtctta
    44941 ttttgtgtga caatcgatcc attaatggtt gaaattgaat tataattggc aataaaatct
    45001 tctaaaccat cacgtagttc tgtaatgtca ttaactgtcg ttgtgcgttc aattaatgcc
    45061 attaacttgt ttatttcctt atcaatgtca gccgattcct tattaatgta cttcatcact
    45121 tctttacgta actttcgttg ctcattttca gataaagcta cttttgtgat aaataatttt
    45181 ttatgtgtta ggacaaacat tggtgaaaag acgatgtcat aatctaatgt gtaattttca
    45241 aatgttctaa gtgaaatcgc atctaagaaa ataatttctg gaaataagtt tcgcaactcg
    45301 tataacatca tttgtgatac tgacgtgcct tgtgtacaca cgataatagc ttttatcttg
    45361 ccatcgaagt tttcatcttg acgtctcaaa ctacctccga acaacatggt taaatatgct
    45421 atttcattat caggcaacga ttttccgaaa tattcagtta acgattgaca tgattgtttc
    45481 accatatgaa ataaggattg ataatttcct tgtaaaggat ttattaattc atcacgatcc
    45541 gttaagttat atttaatcct ataaaaagca ggcgttaaat gtaacaagag ttgctgtgat
    45601 aatttctcct tatcttcaat gttaataaaa gtgatttgtt caaaatggtg aatcatttga
    45661 gcgatggcca tcgttaaatt cgatatgtta tctgattcct gcaaatcagt ccattgcaca
    45721 cttgttgaaa gtaagtgtaa tgtcaaatat aacttttccg cttctggcaa atcaggctca
    45781 tgttgcgtca taatctccgt tgcttgatat tctttcgtat ccctcaaata ctgataatta
    45841 atatttaatg gattcatcac atgaccactt tgaattcgtc tacgaatcac acaaaggaca
    45901 taaggcaatg aactaagtga tttgtctata aagcgactct tcaaaaattg ttctacctgt
    45961 ttgatcttgt ctttttgata tgcgatatct tcgaatgtta agttgagcgc ctttaaaact
    46021 tcacttttag taatatcatg attcaacctt tgatcaatca acttaatgaa gaaacggcga
    46081 acttcaaatt catcaccaac aatttcataa ccatgctttc gagaatactt aagtgacaaa
    46141 ccatgatctt ccaattgctc tttcacatga tttatatcgt gaatgacagt atttttactg
    46201 acttgtaaat caattgaaaa atggtttaga gacattgcat tttccttact aaaaagcatg
    46261 agcattaaat aataacgacg tgtttctatg ctaaaaatga cattgttgcc gtttaacatt
    46321 tgctgctccg atacatctcg cttgaataac gtcatgattt cagaacttac aataaaattt
    46381 ccttggcttg ttctttcaag ttttggataa ccctcttgtt caagccacaa attgattttt
    46441 tgaatgcgat atcctagttg tctacgagac aaaccaaata tcgattcaag ttctttacca
    46501 tgaatagtag gattcaatac aatttctctg agtatttgct gattatcccc gttcatgttc
    46561 gatcctcctt tgagcatctg agctcaattt atcatcaatc gtcacaccga tgtacacact
    46621 ttgaacacat atttccaaaa tgagcatgta catcattgtg atgttttaac aacatttcaa
    46681 ttatatctat attttttgtg attttaatct tttaaaataa agcaattgaa atttttacat
    46741 atatttttgt gttttatgtt ttttgaagca tttttaacat acatatctca atcattatca
    46801 aattgtcatg accaatgtaa tccactataa aaaccctaag gacgcttata tcaggcgcct
    46861 tagggttaac tgtatctatt taattaagta ttattattcg tatgtacgta acttatggtc
    46921 tatcaagttc cacacttctt caacatcaac tgctgtagca aaataagcat tggcaggctt
    46981 acctgtaaca tgatttaaat cgacagccat agtgccataa gttagtggac tttgatgttc
    47041 aatgtcgata ttaacgggta ccattgtaaa caattctggt tgtaacaaat acaaaattgt
    47101 acaagcatca tgtattggac caccatccat attaaagtga gtcttgtatg tcttcttaaa
    47161 gaattgcaat aattctacga cgaactgtgc aacaggatta ttgatacttt caaagcgttc
    47221 aatcacgtga ttgtcggcta aaacttgatg tgttacatct aaaccaaaca catttatagt
    47281 aatcccactt tcaaaaacac gcttcgctgc ttcagcatct acccaaatat tgaattctgc
    47341 tgtaggcgtc caatttccaa atgtaccacc acccatcaaa gtaatagatt caatatgctc
    47401 agcgattctt ggctcacgaa tcaatgccgt tgctacattc gtaagaggac ctgtcgctac
    47461 aattgttaca ggtgtatcac tcgtcatcac tttgtttata atcacatctg atgctggcat
    47521 tgcaactgct tgacgtgatg gtgtcgacgg tagtttcgga ccatctaatc cagattcccc
    47581 atgtatttca gaagcaaagg cagctggttt aattaacggc ctatccgcac ctttcgctac
    47641 tgctatatct tggcgtccca taatatccaa tacgttcaag gcgtttgtcg tattcttgtc
    47701 aactgattga ttacctgcga ctgttgttac agctaatatc tctagtggac tgtcaattgc
    47761 ccccgctaaa attaatgcta ttgcatcatc gtgtcctgga tcacaatcca taataatctt
    47821 tcttttcatt tatatatcca cctttcttaa gttgttatcg atagcttatg tatatttatt
    47881 tatgtggtga atcatgttta ttttgaaaaa tagttttaac tttctcatat ttttggatac
    47941 aaacactatt tatctatttt atggcttata aatttatccg atatgcctta tcaacctacc
    48001 tcgctaaaaa taggatgtct acatatctat accgactttt gtcaactcat tttcacaaca
    48061 atataaacag caatttatat gattgttaca tgattcaaac aatttttatg aaaaatattt
    48121 tcatacacag aatatatatt gatattaaat ttctcaaaag ctatattgag aataattagg
    48181 agggatgttg atgaaatctt tatttgaaaa agcacagcag ttcggcaagt cctttatgtt
    48241 acctatcgca atcttaccag ctgcaggtct attgttgggt atcggtggtg cattaagtaa
    48301 tccaaacacc gttaaagcat accctatttt agatattacc ttattacaaa atatttttac
    48361 attaatgtca gctgcaggta gtattgtttt ccaaaattta ccggtcatct ttgcaattgg
    48421 tgtcgcaatc ggattatcta gaagcgataa aggtactgca ggtttagctg cgctgctcgg
    48481 tttcttaatt atgaacgcaa ctatgaatgg cttattaact atcacgggca cattggcaaa
    48541 agatcagctt gcacaaaatg gacaaggcat ggtgctcggt atacaaacgg ttgaaaccgg
    48601 tgtttttggc gggattatca caggtattat gaccgcaata cttcacaaca aatatcacaa
    48661 agtggtatta ccaccgtatt taggtttctt tggtggctct agatttgtcc ctattgtcac
    48721 agcatttgcc gcaatctttt taggtgtatt gatgtttttc atttggccaa gcatacaagc
    48781 cggcatttat catgttggtg gatttgtaac gaaaacaggt gccatcggta cttttgttta
    48841 tggcttcatc ttaagattgt taggtccact cggtttacac catatttttt acttaccgtt
    48901 ttggcagacg gcacttggtg gtactttaga agtcaaaggg cacttagttc aaggtacgca
    48961 gaacatcttc tttgctcaac ttggtgatcc agatgtgacg aagtattatt caggtgtgtc
    49021 acgctttatg tcaggccgtt ttattacgat gatgttcggc ttatgtggtg ccgcacttgc
    49081 aatttatcac acagctaaac ctgaacataa aaaagttgtc ggcggtttaa tgttatccgc
    49141 tgcactcact tcatttttaa caggtattac cgaaccttta gagtttagtt tcttgtttgt
    49201 cgcacctatt ctttatgtaa tccatgcctt ctttgatgga ttagcattta tgatggcaga
    49261 cattttcaac attacaattg gtcaaacctt cagtggaggc tttatcgatt tcttactctt
    49321 tggtgtgcta caaggtaata gtaaaacaaa ctacctatac gtcataccta ttggaattgt
    49381 gtggttctgt ttgtattaca tcgttttcag attcttaatt acgaaattta atttcaaaac
    49441 acctggtcga gaagataaag ctgcagcaca acaagttgag gctactgaaa gagcacaaac
    49501 tattgttgct ggtttgggag gcaaagataa cattgaaatc gttgactgtt gtgcaacgag
    49561 actacgcgtc acacttaatc aaaatgacaa agtcgataaa gtattactcg aaagtactgg
    49621 tgccaaaggt gtaatccagc aaggcactgg tgtgcaagta atttatgggc ctcacgttac
    49681 agttatcaaa aatgaaattg aagaattgct cggggattaa gactaaccga aatatcaaca
    49741 gaactaatgg caacgatgta cgaagtaaga agtgacatcg ttgcttttat ttttaatgtt
    49801 acatttgaag cattaagttc atcatacact gtagtgagcc cgcaaatcgc ctctgctaga
    49861 caatcatctt aatgctatga ttaaagctta agtgccagat ttgaatttaa tttcaacaac
    49921 gactttcact acattaaaaa tagggctact cgacacatat agttgtatca aatagccctt
    49981 tatacaattt tttgggtaag gttttacaat ttttggaatg gtatagattt tataaaaagt
    50041 tatttaagtt cttctgcttc agccataata tcttttaatg ttttagctga atgtgcgaac
    50101 ttgctttgtt cttcgtcgtt taatgggatt tctacgacgt tgcgaatacc gtttctattg
    50161 atgactgctg gaacaccaat ataaacatct tcttcatcat attcgccttc taataatgct
    50221 gatacagtca atacggcatc ttcatttctg aaaatcgctt cagtaattct agctaatccc
    50281 attgcaacac cataataagt ggcaccttta gcttgaataa tgtcatatgc tgcatcacgt
    50341 gtttgaacaa aaatttgttc aatttgcgct ttgccctcag gacgttgttc aagtaatgtc
    50401 ttcaaaggtt gacccgcaat attagcgtgt gaccatactg gtaattcagt gtcaccatgt
    50461 tcaccaataa tttgagcatc gacgctacgt ggcgcaacat cgaacgcttc gcttaacaat
    50521 aatctaaagc gtgcagagtc taaaattgta ccagaaccta taacacgttc tttaggtaaa
    50581 ccagagaatt tccatgttgc atacgctaaa atatcaacag gatttgtagc taccaagaaa
    50641 ataccatcaa attttgatgc cattacttca ccaacaattg atttgaatat tttcaagttt
    50701 ttagatacta aatctaaacg tgtttctcca ggtttttgtg cagcaccagc acagatgaca
    50761 actagatccg catcatgaca atcactgtat tcgccagctt tcacacgaac tgttgttgga
    50821 gaatatggtg tggcatgttt taaatccata acatctcctc gaactttttc agtgtctaaa
    50881 tcaatgatga ctaattcatc aacaatgctt tggttcacta atgaaaatgc gtagcttgaa
    50941 cctactgcac cattacctat taatacaact ttgttccctt taaatttgtt cattacaaaa
    51001 actcccttat gattaattca ctaacatacg tgtagcttca aatatgttag tttaatgctg
    51061 cttattgacg atacaaaagc aaataaacat ctcttttatt ttcaacgcat aacttaaaag
    51121 gtcatgtgtc atccgctttt aagtttgtga tttatttcac atataaaatg taacatgcat
    51181 taagtactgg gtcaatatta aattgtgatt tatttcacat tttattttaa tttttacacc
    51241 tttttaattt gtatacgatt acatcttagg tgtctttagt cttcgtactt cgccagtgat
    51301 tatttacact ttcacatttt tattatcatg tttacttttt tctaagaaaa caacaatgtt
    51361 ttttgaatta gtcaaataaa tgcgcgcaat cgtcggtgtg caaacagaca attgtacaca
    51421 atgcttattg ataagtattt aaaaaattaa aaatgtcata caattatcaa atttgccatt
    51481 ttatttatat tttctcaaac caattaattg aatatcgaaa tttttagtag aataatcaaa
    51541 atagacagat taaaggagga gtatcatgct tacagaacaa gagaaagaca ttatcaaaca
    51601 aacggtgcct ttacttaaag agaaagggac agaaattacg tcaatctttt atccaaaaat
    51661 gtttaaagcg catcctgaac ttttaaacat gtttaatcaa acgaaccaaa aacgaggcat
    51721 gcaatcttca gcattagcac aagctgtaat ggccgctgcg gttaatatcg ataacttaag
    51781 tgttattaaa ccagtcatta tgccagtcgc atataaacac tgtgcattac aagtttatgc
    51841 tgaacattat ccaattgtgg gggaaaattt attaaaagca atccaagacg tgacaggttt
    51901 agaagaacat gaccctgtga ttcaagcttg ggcaaaagca tatggtgtta ttgcggatgt
    51961 gttcatccaa attgaaaaag aaatttatga tcaaatgatg tggattggtt ttaaaccatt
    52021 caaaattacc aatattaaac aagaatctga agacattaaa tcatttacag ttgaaactga
    52081 agaatatgac tttagtgaat ttacaccagg ccaatacatc acagttgatg tttctagtga
    52141 taaacttcca tatagagcta aacgtcacta ttctatcgta tcaggtgaaa aaaaccattt
    52201 aacttttggc gttaaacgtg atgtcacaac agaacatgaa ggcgaagttt caacaatttt
    52261 acacgatgag attaaagaag gcgatatgat taatttagct gcgcctgtag gtggattcgt
    52321 attagagaat acgactgaac cacaactttt cttaggttca ggtattggcg tcacaccttt
    52381 agtagcaatg tatgaagctg cctctgccaa aggtttagat acacagatgg ttcaagttgc
    52441 tgaaaatgaa caacatttac ctttcaaaga caacttcaac agtatcgcaa gccattatga
    52501 caacgctaaa ttatatacac acttaaaaga taaacaaggc tatattggca ctgaagaatt
    52561 acaagcattt ttagcaaata aacctgaaat ttatatctgt ggtggtacaa aattcttaca
    52621 atctatgatc gaagcactta aatctttaaa ttacgatatg gatcgcgtac actacgaaac
    52681 atttattcca agactaagcg ttgcagtata actgagaaaa gaggtttagt gctcatatga
    52741 aacttaatca acgttacgta aaagtatttg cattatattt cgtaagtatt gttactgcaa
    52801 atattattgt taaaaataat aatttaatta aaacattgat acaaaccata gccgggtaca
    52861 cggtctttgc agttggtttg aagtatttaa ctaaacgtaa aaataaatga catctatacc
    52921 aaaacagcta tgactttact ttgtcatggc tgttttttaa ttgggagtag gacagagatg
    52981 atattttcgc aaaatttatt tggtcgtccc accacaacat gcattgatgt atgctcactg
    53041 aatttcataa gaaaggagtt cacaagatga ccgtagatat tggacggatt tatgacaata
    53101 aagataatac cgacgctatt cgtatcctag tcgatagagt ctggccgaga ggtatttcga
    53161 aaagaactgc taacctagat tattggttaa aagacattgc cccttctact gagttgcgac
    53221 aatggttcca acatgatcct aaactttttg gagcttttaa agaaaaatat gaaaaagaat
    53281 tacgtgatca ggatgcgcaa aaagatgctt ttgaaaaatt aaaggatatt gtaaatcagc
    53341 ataatcatgt tctattgtta tatgcagcaa aagatactaa acataaccaa gctgtagtac
    53401 tacagcagtt gctcaatact tagttatata tgtttatcgt gaatcactat aaatgtcgct
    53461 aacttcattt ctaatattta tttttaaaaa gcataattac tacaattaat tgaactttaa
    53521 taattactaa acttgaacaa cattttactt taacaaaata aagttttaaa atattaattg
    53581 ttgggtttta catagtaatt agaaagagag tgttaatgaa atgaagttta aaagactagc
    53641 aactatattt tcagcagtat tagtgttatc aggatgtggc tcaatgcatt catctggcaa
    53701 agacttaaat atttcgttac cgttaaaaac aaagtctatt gcaccttatg aaacagatgt
    53761 accagttaag attggtgctg cagaatcatt atttaaaaca aatgatcaag gaaaaataga
    53821 aaaagcatta gtgaaatcgt atcatcaacc aaatgataca acgttagata tagaattaaa
    53881 agataatatt aaatttcaaa acggtcaaaa attgactgca gaaaaagtga aatctagcct
    53941 tgaaaatagc atgaaaaaaa gcgacttggt caaatattca ttaccaatat catcaattac
    54001 cgctaaaggt caaaaactga caattaaaac caactccgct taccctgaac ttgtatctga
    54061 attagctaat ccttttatgg caatttatta tacagatgct aaatcagatg ttaatcaaac
    54121 tcctgttggt acaggccctt accaaataaa agattataag caatctcgaa aaatatcatt
    54181 gtcgaatttt aaggactatt ggcaaggtaa accgaaactt gatcatatta ctgtgacgta
    54241 ccaagaagac ggcaataatc gcgtcagaaa tttagaatct caaaaagatg atttaataac
    54301 tgatgtccca gttaataaag ttcatgacat agaaaataat caaaatttaa aagtgtcaaa
    54361 agaatctgga tttagaactt ctttacttat gtataatcat actaataaaa aaatgactaa
    54421 atccgttcgt gaagcattag atcatatcat tgatagacaa ggtattgcag atcatattta
    54481 tcaaggttat gcgaaacctg caacgagtcc atttaatgat aaaattccat atattaaaga
    54541 acctaagtta accaaacaaa atatcgaaca agcaaaaacg ttattagcta aagatggtta
    54601 tacaaaagaa caccctttaa aaattaagtt aattacgtat gacggtcgtc cagagctatc
    54661 gaaaattgcg caagtattac aatcagatgc taaaaaagca aatattgaaa tcgacattaa
    54721 aagtgttgat gacatagaag gttacttaaa agaccgttct gcatgggatg caacgatgta
    54781 tagtttcgga acaatccctc gcggtgatac aggttatttc tttaatcaag catataaaaa
    54841 agatggtgct attaataaag gagactacaa taatagcaac gtcgatgatt taattaatca
    54901 attgaatcat actgtagatg ttaaggaacg tcacaatatt tctaatgata ttattaaatt
    54961 atcaagtcga gatgtaccaa acagttatat tgcttacaac gatcaaatag tcgctgctaa
    55021 ctctaaggtt aaaaattata aagtaacacc tgaaggtatc tatttaatcg attatcgaac
    55081 aacgattgaa cgataaggga gtgtgggaca ttgatttatg tctcagccct gcttcaacta
    55141 taaaaaccac gccgaagtca tccaatatga ttatggcgtg gtttaatttg cttatatgat
    55201 tgtattaatt tctgtttgat gaatttcaat aaaatgatta ttacatactt tcaatgaatc
    55261 atgttcattt tatataaatc taattgtcac tatttgttta acgtgaaaca cttttttaac
    55321 tccaaaaagt attcctattc cactctttta aagacaaatt ataaaaatag cttatgtcac
    55381 aaacatatga gcaacataag ctttaattat tattcgtcta cttttttctg ttgttcttta
    55441 aattctttct gcagtaaatt cacttgtttt aaacctgccc ccattaaaat gaatacaagt
    55501 atccacacaa taacgattaa aataaatatt ttcaacgtat cactgccaag tacagttaaa
    55561 gatgtatccc aaatgccatg taaaccaacg gctgataaaa agaatattaa aaagcgttta
    55621 tcaaaaatat ctttgaattc aaagccatgc tgttctttcg caataactat tgcagcacca
    55681 acaatcgctg accaaactaa atgaccacca atcgcagtcc acgcacgtgt gaagacaata
    55741 tctaataatg ggacattttc ccctaaagcg aaattcaaaa tataacctgc tgattcaaaa
    55801 actgcgaacc ctgcaccaat agcagcaccg attaataatc cattcaaaat cttatttgtt
    55861 ttcaatttat tgacgaaata aacaataatg agtgcttttc cagtttcttc aactaatcct
    55921 actaaaaatg catcgaaaaa tgttaaagaa ccaaaccttt cgaattgatc actaaaaacg
    55981 acaaatctat ataataccat cgtacttagt aatgaaaata cgccgccaat aaagaacatg
    56041 ataataactt caaaaatgct aatattttta aacgcatttg attcataaaa gaagaacaaa
    56101 cccgataatg gtactgttaa agcccctata aaaatgagac ccggaatcgc gttagtgtta
    56161 ttaaaaatcg ctgccatgac ccataatcca ataaatgtta ctgtgaaagc gatgaatact
    56221 cgagaaaaga gccatggctt cccccattct tctgatatgt cacaaattgc tggcgtagtt
    56281 ttagcagtac ccgctataaa tatttcatct gcttcgtttt tagtatgcgg cttaaatact
    56341 tcagaaaaca tatcttttaa attaagattt aagctttcat cattgccggc tagtctaccg
    56401 attgatttgg ttgcattatc aaataaactt cttgcttcgg tttttaaatc tgcattttgc
    56461 gctgtttcat gcgctttggc ttccatttgt ttattgatag attcattatg tatgtcggac
    56521 gtcttagttg attgtgtact tgctgatgac atcccctctt cacctgtatt aggtgcaact
    56581 gattgcgttt gtgttgtctc ttctttttct gtatttcttc gatgattaag accttccata
    56641 gacttaccta ctttcacttt tcataataaa actattttaa tttaatattg atggattttc
    56701 catattttaa tataaatact ttgttcgatt gggcgctttg tatttcatat ttaaaactca
    56761 aaacctattt aactttttat attccgagca atatttttat ataagtattt taatgatatt
    56821 caattcatta caaacccttg atattacaat tgttatcaac cattaaaatg tgtctatact
    56881 gtgtctatta tcagaataaa aagatatttc taattgattt taaacgtcgt tatgttatat
    56941 ttcttgtaag ggtttacaca aagtgtaaaa acgctatatt ttatcaaatg tgatggaggt
    57001 gacttgcttg aaacaaatca catggcacga cttacaacat atcattaaag atggtgatgt
    57061 gattggttta ccagcattag ctgtagccaa cttacccgcc gaagttctac gtgctgtgtt
    57121 agcgcaacat gacacatatc atacgcccaa agatttaacg tttatattag cgaatgatat
    57181 ccatagttta ggtgccgcac cggatttaga tgattttata gaacgtcgca tgattaaacg
    57241 tgtcattatg agcattttaa cggcttcttc caaaacggca caagcaatga aaaataatga
    57301 cattgaagct tattttttac cacaaggtat cattgcaact cattatcgtc agagtaatca
    57361 attattacct ggagttatta ctaaaatcgg attaaacaca gctgttgatc ctagatacgg
    57421 tggcggtaaa gtaaatacac gaacaactga tgatttagtt tcattagtaa ccatcaacga
    57481 tgaaacatac ttacattaca cattccctag cgttgatgtg gcactactga gaggaacata
    57541 cgcagatcaa caaggtaaca tttatttaac tcaagaagcg tacttgagcg agtgttatca
    57601 tgtcgcatta aacgcgaaag ccaatcatgg gaaagttatt gtacaagtta aagctttagt
    57661 tgacgactat caactaaaac cgaatgaagt tgttatccca ggaaatcttg tcgattatgt
    57721 atacgtcaca gaagatgaaa agaatcaccg ccaagtaatt cagagtcatt atttaccagc
    57781 cttgtctgga gaagaacgaa ttgatggaat acctgaaccc gcattacctt ttaatagtcg
    57841 caaattgatt ctccgacgtg ctgctcagtt tttaacttat ggcgatacaa ttagcatcgg
    57901 ttatggcatc aataatgaac tctctaattt attgcacgaa gaatgtgttg aacatgatgt
    57961 gcaaccgatt ctagatgttg gcattttcgg tggattcgtt gggagtcgtg aacattttgg
    58021 tatgaattac aatgcagatg tgcgcatgcc tcatgatcga gcatgggatt ttatttataa
    58081 caatggtgta tcagttgcct atcttagctt tgctgaggtt gatcaatacg gcaatgtcaa
    58141 cgtgtcttac ttcaatgacc gactaaatgg atgtggtggc tttatagaca ttacgcaatc
    58201 tgtaaataaa attatctttt caggtacttt tgtagctggc agtcatgtct catgtcataa
    58261 tcaacgatta aacattgaaa ctgaaggaca aaaccagaaa tttgtatcag atgtgagcca
    58321 tatcgacttt aatgcacaat attcacaatt actcgagcaa gaagtctatt ttgttactga
    58381 tcgtgcagta ttcgagctca ccaatcaagg cttgaaacta attgaaattg caccaggtct
    58441 tgatttgcat aaagatattt tgaatcaaat ggcttttaaa ccaattattg ctgatcattt
    58501 aaaattaatt gataccagca tttacaaaga aaaatgggga caacttaaac aatcaattca
    58561 taaagtatga aagtgaagct aaagggggta tactaatgaa tttcgattgg ataaaaacgc
    58621 gttcagactt cgatgatgac aagcctgccg ttattgatca cgcaaaacaa acatcttgga
    58681 cataccaaca actcaatgca cgcgctgata atatggcaca ttatttaaca tctcaaggtg
    58741 ttaaaaaagg cgatgttatc ggtatttttg cgccaaatga tattgcaata ttagatttat
    58801 tgtttgcttg ttttaaaaca ggtgcggttt ttttaccatt gaattggcgg cttaacccaa
    58861 aagaaattgc agccattgtg gaagatgcac aattaaaact gctcttctat gctgaaaaac
    58921 atttaagttc actcaccgat attgaccaaa acttattgca tatggatatt gatgtggcgc
    58981 aatatgatga aatcgtaaat ccagattatc accaaccttt tcaagcaaca cctgttgaac
    59041 cacaagatct tgcagcatta atttatacaa gtggtacaac cggatcacct aaaggtgtga
    59101 tgttctcata tgaatcattt gttcataacg gtacaaactt agagctgacg tacaagttca
    59161 attcaaacta tattacgatt gtatcaacac caatgttcca tgttttaggg tttaacgata
    59221 ctgtattacc agtattaatg tcaggtggca cacttattct tcaacgttac tttaacggcg
    59281 aagaattgaa tgacatgatt gcacaatatc accctacatt tattatcatg attccgacaa
    59341 tgtattatag tacgctacgt gctagtaatt ttaatcctga aaattttaga gctatggatt
    59401 atatcatcca aggtggttca caaccattac caagtatcca agcagctttt aaacaatatg
    59461 gcataaacat tattaacggc tatggtttaa ctgaagcacc tcttgtactt gttaatacac
    59521 cggaaaattc aaaacgtaag ccaatgagta ttggtaaagc agtcatgttc gttgatgcac
    59581 gtatccttga tgataacggt gaggaagtac ctactggtga gattggcgaa cttgcaatta
    59641 aggctaaaaa tgtcacgcca ggatattgga ataaaccagc agagactgcc aaagcatttc
    59701 atggtcgtta tttattaact ggtgacttag cgaagatgga cgacgatggc gatatattta
    59761 ttattgaccg caaaaaagaa ttaatcataa ctggtggcga aaatgtctta ccatctgaag
    59821 tcgaaaatgc tttagctgag catccactag tagaccggtg tgtggtcgtt ggctatgatc
    59881 atccaaaata tggtgaatca attgctgcag ccattatact tcgcgaagat gaacctcatt
    59941 acgctgaaat tttagatcaa catatgcgaa gtcgtttagc aggttataaa gtcccaagaa
    60001 tgtatgtacc agtgacacat atgccgttaa acagtacgca gaaaccagat aaacttgcga
    60061 ttcgacaaat gatgaatgac aaagtctcac aaacacttta aaggtgataa aaatttttga
    60121 catttagtgt aagcgtttac aaataaagcg tgttgttttt gaattaaatg catttcacat
    60181 tagtattcat attattttta ggaggaattt atatgacatt tgaaaaagaa acggtcttaa
    60241 aaacattatt tcctgaagat gtacttagta ttgctaaagg tttaacagac ggtgaagtcg
    60301 aatttttaca acaagtagat tcattgctag aaagtaagta ccgtgaaaat attaatcaac
    60361 attggataga cgctactgta cccgaggact attttaaaga tctgggagaa ttaaattatt
    60421 ttaacaatcc attactttac aaggatcgtc caaacgccaa aatgcctagt caactatttc
    60481 agtttttcat gtcttaccta ctcgcgcgat ttgatatttc cttagctacc ctactcggtg
    60541 ttcaccaagg tttagggcat aacactttct atttcggagg tagcaaagaa caaattgcga
    60601 aatatgtacc taaattacag tcacatgaac tgcgtacatg ctttgcttta actgaaccag
    60661 aacacggttc ggacgttgcg ggaggtcttg aaacagtcgc tgaacgccaa ggcgatactt
    60721 gggttatcaa tggtgaaaag aaatggattg gtggtgcaca tgtatctgat gtcattccag
    60781 tattcgcagt aaataaaaaa actggcaaac cccattgctt tgtagtcaga ccagaacaag
    60841 atggcgtcga tattgaagtc attgataata aaatcgcact tcgcattgtt cctaacgcac
    60901 taattaaatt aactaatgtc aaagtagatg aagcggatcg cttacaaaac ataacaagct
    60961 ttaaagatat tgccaaaatt ctttattcaa cgagagcagg cgttgcttat atggctacag
    61021 gtggtatggc tggcgcttta cgtgccacat tagattatgt cactgagcgt aagcaattcg
    61081 gcaaaccaat tagtaaatat cagttaatac aagaaaagct agcaatgatg caaggtaatt
    61141 tagctcaagc aatggcaaca tgtgctcaat tagctaatat gcaagcacat ggtgaatatg
    61201 acgaggttgc aacttcaacg gcgaagatga tgaatgcctt acgtttgcgt gagacagtag
    61261 ctatgggccg cggtattaca ggtggtaatg gcatactagc tgacgattat gatattgcac
    61321 gtttcttctc tgatgcagaa gcgatttaca cgtacgaagg tacacatgaa attaatgcct
    61381 tagtaattgg acgcgctttg actggagatt ctgctttcgt ataaatagca aataattata
    61441 tgagatgcat taatttcact aaaaaagact tattttaagc ataaagcttt ttccttaaat
    61501 aagaggctaa gatgactgtc aaagatactt aattaatttt ataaaatagc aacgttattc
    61561 caattatctt aatggttatc ttatcctcaa ctaaattgga ggaatcacta tgacaattaa
    61621 taaagtaacc gttcttggcg caggcacgat gggcgctcaa ctggcagcac tctttgtgaa
    61681 tgctggactt aaagtaaaac tattagatat tgtagtggac aaaaacgatc caaatctcat
    61741 tgcgaaaaaa tcttacgata aaattacaga taagaaacgg ccgctactat tcgacttaaa
    61801 tctagtgagt catttaacat atggtaattt tgatgatgac ttggtaaatg atgatgctga
    61861 tttatatatc gaagcagtca aagaagatat tgaaattaag catgctgttt ggcaacaagt
    61921 tctacaacat gctaaagaag atgctttatt tgctacaaat acatcaggta ttccaattaa
    61981 tgcgattgct caagcattta acgagaagga tcaagaacga ttctttggtc tacatttctt
    62041 taacccacca cgtattatga aattagtgga gttaatacct acgtcacaca cgaaggaatc
    62101 tatcatatta gatgtaaaaa atttcgcgca aaatgtatta ggtaaaggtg tcattgtcgt
    62161 caatgatgtg cctggctttg tcgcaaatag agtcggcacg caaacaatga atgatattat
    62221 gtatcgcgcc gagcaacaca agttaagcat tgtagatgtg gatgctttaa ctgggcaagc
    62281 gattggtcgt cctaaaacag gtacatatgc cctatccgac ctagtcggtt tagatattgc
    62341 agtgtctgta attaaaggca tgcaacaagt acctgaagaa acgccttatt ttcatgatgt
    62401 caaaattgta aatacgttgt ttgacaatgg cgcactcgga cgtaaaacga aacaaggatt
    62461 ttacaaaaag gataaagaaa ctaaagctcg acttgtttac gatgttgaaa aacaagatta
    62521 tgtacctgta tcgcaaccac aattaccaat tttaaatgaa tttaataaag acttagtgca
    62581 taaccttgat gtcatattca atgcgcaaga cgaagcggga ctatttttat gggagacatt
    62641 acgtaataat ttctattact ctgctatcaa tgtacctaaa gctaccgatg atttccgaga
    62701 catagaccgt gcgcttgtct gggggttcaa ctggaaactt ggtccattcc aattatggga
    62761 tgcaatggga tacgaacgtg ttaaaacacg tatggaagac gaacttggag acttaccaca
    62821 atggattagt gatttagatg gtggctttta taaacaagat gagaccattg aatatgcaac
    62881 acctgtttct cacttcgtaa aagatgaact ttgggataaa ggtgatgcca aactttccgt
    62941 aactcatgat gatcaactgt tactgaaatt acaaagtaaa aataatgtca ttaccgatga
    63001 attcaacgat gcgttagttg atgccattga tttactggaa aatgaccatt acacaagtat
    63061 ggtcatttat gcagatggta ataatttcag tgtgggtgct aaccttttct taatgaaaaa
    63121 ggcgcatgaa gacggtcttg tagatgatgt cgttgcacaa tcaattgata aattacatta
    63181 tagctttaat cgtttgaagt atagtttgaa accagtagtc acagctgttc aaggtcgtgc
    63241 cttaggcggt ggctgtgagc ttgtacttta ctcacctatt gttgtcgctg caagtgaaac
    63301 atatataggt cttgttgaag caggcgttgg cttattaccg agtggcggtg gccttgcaga
    63361 aatggctgat cgcatattac gcacatcgca taagtttgat gacaaacaag cttccatgac
    63421 aaaagtactg acgaatatcg catttgcgaa agtctctaca aatgcctttg aggcacgtcg
    63481 ttatggttat ttacgtgata cagatacgat tattttcaat acagcacaac gtgtcgaagt
    63541 tgcgctcaaa cgtgcgaaat atgaagcaga aacaaactat attccgaatc ctagacatca
    63601 atatatcgct ttaggtgaag acttcaaagc attgatccaa ggacaattag atgcgcaaag
    63661 acgggggcat tttattagcg accatgatta tcatatcgcc ttaaatatcg ccacaatttt
    63721 agcgggtggt gatttaccaa gaaatacatt tataaatcaa cgttacattc aatcgttgga
    63781 gaaaattggc tttattgact tactaaaatc taaaaaatca tatgaaagaa ttgcacatat
    63841 gttaaaaact ggtaagccat tacgtaatta aaagatagtc attaagagag gatgataacc
    63901 atgcaagaag catacattgt agcttatggg cgttcagccg cagcgaaagc aaagcaaggc
    63961 gcattattcc acgaaagacc tgatgatgtc gcagccaaag tattacaagg cgtattgaaa
    64021 cgtattgacg gaaaattcaa taagaatatg attgaagatg tcattgttgg tacggctttt
    64081 ccagaaggat tacaaggaca aaacattgca cgaacgattg cattgcgtgc gggattatct
    64141 gacacggtac cgggtcaaac agtgaatcgc tactgctcat caggattaca aaccatcgcg
    64201 attgcagcca atcaaattat ggctggtcaa ggagatatac ttgtagctgg tggcgttgaa
    64261 ttgatgagtg ccgtaccaat gggtggcaac gagcccacaa acaatccaac cttacaatat
    64321 gatgatatag gtgcgtcata tcctatgggt ttaactgctg aaaatgtagc atcccaattt
    64381 gacgtatcac gcgaagatca agatgcttat gctgtcagaa gtcatcaacg tgcctatgac
    64441 gcacaacgtg atggtcggtt caaagatgaa attattccaa tacgggtaaa ctcagttgaa
    64501 tatacaaacg caggaccaaa agtacacaca aatatctttg accaagatga atttatacgc
    64561 cctgacacca cgatggaggc attagccaaa ttacgtacag tatttaaagc tgacggcact
    64621 gtgactgcgg gaacatctgc cccactttct gatggtgcag gatttgtagt tttaatgtct
    64681 ggagataaag tgaaagaact aggcgtgaca cctattgcac gattcgttgg ttataaggca
    64741 gtaggcgttg acccgaaaat tatgggtatt gggcctgcat atgcgattcc tgaagtattg
    64801 tcactcagca atctatctgt tgaagacatt gatttgatcg aattgaacga agcatttgct
    64861 tctcaaacga ttgcatctat taaagaagta ggtctagata tatcacgtac gaatgtgaat
    64921 ggtggcgcta ttgctttagg tcatccatta ggtgctacag gggcaatgtt aaccgcgcgt
    64981 ttacttaatg aaatgggtag acgtcccgat agccgttacg gcatggttac gatgtgtatt
    65041 ggtgtcggca tgggtgcagc tgctatattt gagtatgtgc gttagaatgg ttgattttgg
    65101 atgaagcgga ttcgttaggt tattgaatga agtaggctga agttgaagcg ggttgaagca
    65161 atttcgtttt attaatgaag ctgtgtgaaa tatagtgatt gaacaaaaaa gtggtttaat
    65221 gggatggtgg ttatttccgt tttagaattt aacatttaca cgtctaattt taatcattgt
    65281 tttaaatttt atgaatcgaa gccctttgat ttaataatat ttgctaatgc tagtaactta
    65341 tctgattgtt catgtttaaa ataaagaaaa ccactcacat cagtgtgtgt tcgaactaga
    65401 cttgtaagtt ccagttcggt acgactttct aaagcaatta ttattgctgt gattgtcgta
    65461 tatcacttag atgtgcgtgg tttattttaa taggttagta atatattagg tcatgttatg
    65521 tttaagacta taatgaataa ataatttaga aatatgcttc cgattgttcg atgctttaat
    65581 tcagttagaa gcatcataga atgcatgatt actgttgtat agatacataa ttctttgtat
    65641 tgactgtatg tctttggata gagttataaa tttattttgt tactctaggc ccatatgtcg
    65701 cagtaccatc tgcatgtgtt gttacgttat atgcgtttgt ttcgcttggc tttttttgtg
    65761 tcgggcgagc gccatatgat acttgaccat ttgcatgtgt tgttacgttg tatgcatttg
    65821 tttcgcttgg cttcttgtat gtcgggcgag ctccgtatga tacttgacca tttgcatgtg
    65881 ttgttacgtt atatgcgttt gtttcacttg gcttgttttg tgttgggcga gctccgtatg
    65941 atactgtgcc atcttgattt gtcgttacgt tgtatgcatt tgtttcactt ggcttgttga
    66001 atcttggtct cgcttcatat ccaaatgttc catcgttgta ttcacggata cctgtaccag
    66061 catctctata tttcacatac ttaggtgttt tgttaaattg cggtctcgga ccatattgag
    66121 aagcttctgt tgtttcagtt gcttgaggtt taacttcaat atcacttgat tctccttgaa
    66181 tacctttcaa cgttgattca gtaccttgtg gttttatttc aagtttagat gagctacctt
    66241 caagaccttc taaaataggg ttcggtgtcg tcggttgagt ataattatcg cttaaagatg
    66301 gtctgttttg ttccattgtt agaaaatcgg gaccttgaac gatttcacct tgtaacgttt
    66361 tattttccat cgttggatat tctggacctt ttacagtttc accatagatt gtttcttgtg
    66421 gaatttttac taatggctgt gccactggtt gtgttgtttc ttcagcttta ccagccgtag
    66481 ttttaacctc ttgctggttt ccaactttag gtaattgagg ttcttcaact ttcttctctt
    66541 cttttacaac aggagatttt gttacagttt cctcgtattt tttgacagtt ttatttttcc
    66601 aagattcgtc tgcttcttta actgcttttt ttgtttcttc aactaattta tcaaaattag
    66661 gtttattttc actcttctct ttaaaattgt gttttgttgg atcatatttt gttatagaat
    66721 tcggtctatt ttgtttagtc tccataaaga aatcatctat aattgaattt aagtcatcga
    66781 tcatttcttt ttttatacgc tcatttgtaa ttttatgtgg attgtctgta tctccaagga
    66841 ttaagtccag ttttgctcgt aactctttcg catgctcccc ataatcctta tcagcataat
    66901 aagttacaac taatgtatca atttcagaaa caaggtcata aacttcttta gttgccttgt
    66961 cttctccatc tttatcaaac tgcttcaagt caacattttt atgctctatt tctttaactt
    67021 ctttattaaa ttgataaact gcatctttca aagagttaaa aatatcgtta tattcattca
    67081 ttgttaaatt gtaaagatta tatttatgga aagtaagcat attagtgttc ttatttgaac
    67141 ttttatacca ctttttataa agctcatatt catcaatctt tttctttaat aaatactggt
    67201 cttctcctaa tactcttgtc atcaatctat ctttcgcttc tttatagata ggatctccat
    67261 atttataatc ttccaataag tctattgctc cagtaaattg tgcctctaaa ctatcaatta
    67321 ttttccaata gtaataatct gaaacagtag ctcccttttt acttttctca ttcactcttg
    67381 attctttact ataatccttt gttactatcg catctgcttt gttatcccat gtaaataagc
    67441 tagatgcaac tgctaatgcg cctagcgaaa ttatttgctt tttcataatt ttttaattcc
    67501 tccaaaatgt aattgcccaa tctacattaa agaaacaaaa tattaaaaga cattaactat
    67561 atattaacta gaataaacaa agcattaact atctttttgt tatagttaat tagctttgca
    67621 atatacaata gtgtataatt tttttgatta atgtacatca aaggagtaac aaagcatgac
    67681 aacacaaatg aaaatcaaaa catatttagt tgctggtatt aaagcggcgc tccttgatac
    67741 gactggtatt aaattagcaa gcaaatctga aactacatca catacgtatc aacatcaagc
    67801 gcttgtagat caattacatg aattaatagc aaacactgac ttaaataaat tatcgtacct
    67861 aaatttagat gcgtttcaaa aacgcgatat tttagctgcg cactatattg caaaatcccg
    67921 ctatacgcac taaaaatttg gatcaaatga ctaaagcgaa acaaagatta gaaagtattt
    67981 acaattcaat ttctaaccct ttgcattcac aaaacaatta ataattcacc aataaatcat
    68041 gtaagtgttt gtgacgccaa attgccatac aaatacttgt catatgaata taaacgaatg
    68101 aaacgattgc ctatcccata gatggcaaca ttaaaaagac ctctgaaggt atcatcttga
    68161 taactttaga ggtctttgtt tatattattc aaacaaaatt cttatagaac gatcgaagta
    68221 tgtttcgtct ttcttttctt ctttaatctg atcagctaat gctgggtcat ctgtgataat
    68281 accatcaaca ttggtttgta agtatttcgt taaatcttct tcgccgttaa tagtccaagt
    68341 atagacttct ttattttcca agtgcgcttg attaacaagt cttggcgaat aagaaaaatc
    68401 ttcgatgaca aagaaatcta atgatgtttc tttaaaatga ccaaactgca acggaatgat
    68461 ataaccacac ttgagatatg gcgcttcttt tttcaactta gtcatcacat cataatccaa
    68521 agacatcaca cgatattgat gttcaacacc atgctttttc aaaatatcaa taacacgttg
    68581 tgtataatct gctggttctt taccatgtgg ctttaactca actagtagct tcacatttga
    68641 ttgtttagcc gtttcaataa attcgtctaa ggatacaagt tttgcttcat gtccattttg
    68701 acgcattttc aaaccgacga catctttgaa attagattca gaaatgtttt tattaacacc
    68761 tgttaaacgt ttcaaattgt tatcatgact aacaacaaat tgtttatctt tcgtcataat
    68821 tgtatctaac tcaacgtatt cgacattcgc ttttgcagca gctttcaatg acggaataga
    68881 attttcaacc cctttatctt cgaaaccacg atggccaata atggagatat ttgtattgat
    68941 agtattattg taaagtaagt acatgttata accgataaaa catgtcactg caagcaccat
    69001 tgaaattata aagaacctag acttccgttt cggttttgga tatttaaatt ctaagcccgg
    69061 ttggtctaat acattctctt gttttaagtg cagtactaac acactgatta atgataattt
    69121 cgtaaataaa taatagaaga acaatgcgct tttcaataca acaaataaaa ttgatgagac
    69181 taaaaactta tctccttctt catctacaca aatagcaaga tatgttgctc ctgaaataat
    69241 taatgttaaa atcgcaccaa tgatgagttc caatataact atttctataa caagtcgaaa
    69301 cttatttcgc ttcgtaattt gccaacttag tctcatattt ttaaataacg actggcggtt
    69361 taaaatcgtt aacggtaagg taaatattaa tttaaagttt aatataaata cagcaatcat
    69421 aaaggtaccg taaatgatta tacctttcgt cgttttcata agttcttccg ttaaaaattt
    69481 aggtatgtaa atattttttg ttaatactga acttagtcct aggttggcaa tgggtatcat
    69541 taacattaaa taaatgacaa agaaaataac tggtacacct atgagtttac gcacatttac
    69601 aaaggcattt ttaaaaatgg atttaaatgt aataatctgt cgatcaaagc cggcataaac
    69661 catataaact aacaatgaaa actctacata aatcagaaag gcaacactta atatgaatat
    69721 aataagaagt atcacactgg caggatgact tatgatttcc atccaattgt taatcgtaag
    69781 ttggctttgc ccagctactt ttaacatcat attaaatagt aaaattaagt atgtactact
    69841 aataaaaatc atgattaact gcaatagtaa ggcattaatg ctaaaacgcc ctttattttg
    69901 atacagtaat ttaaatactg cccatatatc tttactaatt ctcttcataa tcacgctccg
    69961 cattgcttta atattaagtt ttatcttaat atttttcatt actcagggtc aataaaaatt
    70021 tgaaaagact catattcata tgcaagtagc aattaataac ccattcgatg atattggaac
    70081 cccaccttta acaaggcatc acattcttta tcagcatagc tacttacaaa aacgtattcc
    70141 ttcaaccatt gtaggacttg tctcatatac ttactacgtc ttgctaatac tcaatactca
    70201 attgaaaaag aagcatatgc cccttcactc ttgaagttgc atatgctttc ttttcggtct
    70261 gaattgtatt tataattcaa cgggaatttt ccctttgaag ttaacataac ggtaggctgc
    70321 tttaacagct tcatcatcgg gcgcttcgac atcttctaat tcatatgcaa tgcccaatgt
    70381 tttccactta tgaacaccta actgatgata tggcagaatt tcaaactttt cgacgttatc
    70441 aagagaatta atgaattccc ctagtttaat taaatcgtct ttatcatcag aataaccagg
    70501 cacaaggaca tgtcgaatcc atacaggttg tttcatatct gacagtttgc gcgcgaagtt
    70561 aaggatgtgt gtattaggct ttcctgtcaa tctaatatgt ttgtcattat caatatgttt
    70621 tatatctaat aatatcaagt ctgtatgttt ttgtaattct tcaaaatgcc tttgaaatgc
    70681 ttttgtatca ttagcacatc cagccgatgt gtctaagcaa gtgtgcacac cattttcttt
    70741 taattccgca aataattttt ctaagaatgg catttgtaac aatggttcgc caccactgac
    70801 tgttacaccg ccacccgatg catcaaagta tggtttgtat ggtaatattt cattcaccat
    70861 ttcatcaact gtgacttctc ttgatggctc actaattttc caagtatctg gattgtggca
    70921 atacaagcat ctaagtaagc atccttgtgt aaataatata tatcttaatc ccggtccatc
    70981 gacagtacct aaactttcga cagaatgtaa gtgtccctta agcatagtgc tcccacctta
    71041 aattttgtta catactttca tggaatgtac gagaaattac atctaattgt tgttcacgtg
    71101 ttaatttaat gaagttaaca gcgtaaccag atacacggat tgttaactgt ggatattctt
    71161 ctggatgttc cattgcatct attaatgttt cacggttaaa tacgttaata tttaagtggt
    71221 gaccacattg cattgcgtaa ccatctaaca tactagttaa gttacggttt tgatcttctg
    71281 gttctttacc taatgatttt ggtacgatac tgaatgtatt tgaaatacca tctttacagc
    71341 aatcgtaagg gatcttagct acagaactta atgaagataa tgcacctttt tggtcacggc
    71401 catgcattgg gtttgcacct ggagcaaatg gttcgccagc tttacgtccg tctggtgtgt
    71461 taccagtttt cttaccgtat acaacgtttg aagtaattgt taatacactc attgtatgtt
    71521 ctgaatcacg atatgtttta tgactacgta atttagtcat gaagcgttct actaaatcaa
    71581 ctgcgatatc atctacacgg tcgtcattgt taccgtattt agggaagtcg ccttcgattt
    71641 caaagtctac tacaagacct tcttcgttac gaattggttt aacttgtgca tatttaattg
    71701 cagataatga gtcagctgct actgataaac cagcgatacc tgttgccatt gtacgtacaa
    71761 tttctgtatc atgtaatgcc atttcaatac gttcatagct gtatttatcg tgcatgtagt
    71821 gaataacatt taatgagtta atgtaaacac ctgctagcca atccatcatt tgatcaaatt
    71881 tcttgaatac ttcgtcatat tctaatactt cgctgttaat accttcgaag tttggaccaa
    71941 cttgtgcacc agatttttca tctttaccac cattgattgc gtaaagtaat gttttagcta
    72001 agttcgcacg tgcaccgaag aattgcattt gtttaccaat tgtcatcgct gatacacaac
    72061 atgcgatacc atagtcatcg ccatagcttt cgcgcataat gtcatcattt tcatattgga
    72121 tagaacttgt tttaatactc atttttgcac agtatgtttt gaagttgtca ggtaaacgta
    72181 ctgaccataa tactgttaag tttggttctg gagctggacc taagttatct aatgagtgta
    72241 agaaacggaa tgagtttttc gtaacaagtg gacgtccgtc aatacctaca ccaccgatag
    72301 attcagttac ccaagttggg tctccagaga ataattcatt gtaatcaggt gtacgagcaa
    72361 atttaacaat acgtaatttc atgatgaagt ggtcaataat ttcttgaact tcgctttcag
    72421 taataacgcc tgctttaagg tcacgttcag catagatatc taagaatgtt gatgtacgac
    72481 ctaaactcat tgctgcaccg ttttgttctt taattgcagc aaggtatgct aagtataacc
    72541 attgaactgc ttctttgaag ttttctgctg gacggcttaa atcgaaacca tatttttgtc
    72601 caagttcttt taattctttt aatgcacgat attgttctga taattcttca cgtaaacgaa
    72661 ttacatcttc tgacatttct gtagacatcg tgttgaagtc gtgcattttt tcttccatta
    72721 agaaatctac accatataaa gctacacgac gatagtcacc gataatacgt ccacgtccgt
    72781 atgcatcagg taaaccagtg attacacctg ctttacggca gttcaacatt tctctagaat
    72841 atgcatcgaa tacaccttgg ttatgtgttt tacgataatc tgtaaagatt ttttcagttt
    72901 cttcgtctaa ttcgtaaccg taagcttcac aagctgcttt cgccatacga ataccaccga
    72961 atggttgcat tgaacgtttg aatggctttt cagtttgtac acctacaatt gtttctaaat
    73021 ctttgtctaa ataaccagca tcatgagatg tgattgttga agctactttc gtgtccatat
    73081 cccacatgcc gccacgttca cgttcttctt tcgataactg cattacttgt tcccaaagtt
    73141 tagaagttgc ttctgttggt cctgctaaaa atgaatcatt accttcataa agagtgtagt
    73201 ttaattggat aaactctctt acatctacgt gtctgttcca tcttccattt ttaaatcctt
    73261 gccaagctgt tgcatgattt ttatttgttt ctaacatact aaacgcctcc atctgtataa
    73321 tgttgtgaat ttgaaatgct atgttaacgt tttcatagtc attgtagcat gtttgttgtg
    73381 atttttttca cataaattat gtacaatttt catcaaatgt atgtcaaaac atagaaactg
    73441 tactaatttg tgtaacagta atatgctaat tgcattctgt tacacaacag ttataatgtt
    73501 cactattttc attgctttaa aagttaattt aggagtatat atttgtttat aaaaaatgat
    73561 tgttgataag cgttaaatca acacttagaa agatttactt ttatatatga agagactgga
    73621 ttaaatactt ttattgacgt aaaaattcac ttttgaaccg ttcaatatct tgccgatttt
    73681 tatataacag ctacaaataa aatataacag tttgatttta cagcctcggt aaatcgtctt
    73741 gacaaacaaa aattttgtgc tatcacaaca tttgcaacgt cttaacaagt catctataaa
    73801 catttctaaa tatttaacat tacttatgcg tcatttattg ctaaaattat tgtattaaaa
    73861 tatacataga attgatggga tatcatgaaa tcaaaaattt atatcttgct attatttctc
    73921 atttttttat catcatgcgc taatacgcgt cactctgaat cagataaaaa tgtattaaca
    73981 gtttattctc cgtatcaatc aaacttgatt cgtccaattt taaatgaatt tgaaaaacaa
    74041 gagcatgtca aaattgaaat caaacatgga tctactcaag tactgctttc aaacttgcat
    74101 aacgaagatt tttcggagcg tggtgacgtc tttatgggtg gtgtgttatc agaaacaatt
    74161 gatcatccag aagattttgt tccctatcaa gatacatctg taacacagca attagaggat
    74221 tatcgctcga acaataaata tgttactagt tttctattaa tgccaacagt tatagtagtg
    74281 aattcagatt tacaaggaga tattaagatt cgaggttatc aagatttatt acaacctata
    74341 cttaaaggta aaattgcgta ctcaaatcca aatacaacaa cgacaggcta tcaacatatg
    74401 cgcgctattt atagcatgca tcatcgagta agtgatgtgc atcaattcca aaaccatgcg
    74461 atgcaactgt caaagacgtc taaagtcatt gaagatgttg caaaaggtaa atattacgca
    74521 ggtctaagct acgaacaaga tgcacgcaca tggaaaaaca aaggttatcc tgtatcaatc
    74581 gtttatccaa ttgaaggaac aatgttaaat gttgatggta ttgctttagt taaaaatgca
    74641 caccctcatc ctaagcgtaa aaagttagtg caatatttaa caagccgctc agtacaacaa
    74701 cgattagttg cagagttcga tgccaagtca attcgaaagg atgttagtga acaaagcgat
    74761 cagtctatcg aaaatcttaa gaacatacct ttaataccga aatctaaatt accggacatt
    74821 ccacatcata aatttttgga gatgattcaa tgacggcata caaaccttat agacatcaat
    74881 tgagacgatc gttatttgcg tctactattt ttccagtatt tttagtcatt attattggac
    74941 tagtaagctt ctatgccatc tatatttgga ttgagcatcg tacgattcat caacatgttg
    75001 atgaaagtca gtcatcttta catcacactg aaaagcagat tcagacattt attacacagc
    75061 ataataattc gtttcaagag ctcgatttaa caaatcatca tgatgttacc gctacaaaac
    75121 gtgaattatt aaaattaata caccaacagc ccgcaacact ttattatgaa ttatctggac
    75181 caaatcagtt tataaccaat aattatgaac atttaaacac taaaaatatg tatttatttt
    75241 caacgcatca gcttaaattc aataatagta catatatgct taaaatttat atggctaaca
    75301 ccccacgttt aagtgaaatt aagaaagata gccgacaatt cgcacttatc gttgatcaat
    75361 atgacaatat tttatacgcc aacgatgacc gttttactat aggtgaaaag tatagaccgc
    75421 aacaattcgg atttatgaat gaatctgtaa aattaaacca tgctgaccat cgtctcatta
    75481 tttataaaga tatacatgaa aacattgaag atggtatcac gttgttaatt gttatggccg
    75541 tagttcttgt tttactagta atatttggtt tcattagcgc agataatatg gctaaacgac
    75601 aaacaaaaga tatcgaaacg attattcaaa aaatttacta tgccaaaaat cgtcatctag
    75661 gtacatatac gcctttaaaa aacaacagtg aactagaaga aattaataat tatatttacg
    75721 atttatttga atcaaatgag caactgatcc attctatcga gcatacagaa cgtcgcttgc
    75781 gtgatattca gttaaaggaa atagaacgcc aattccagcc tcatttccta ttcaatacga
    75841 tgcaaacaat acaatattta attacgttat ctccgaaatt agcacaaact gtggtccaac
    75901 aattatcgca aatgttacgt tactcattac gtacaaactc acatacagtg gaattaaacg
    75961 aagagttgaa ctacattgaa cagtatgttg caatacaaaa catccgtttt gatgacatga
    76021 ttaagctcca tattgaaagt tctgaagaag cgcgtcacca gacaattggt aaaatgatgc
    76081 ttcagccact catagaaaat gctattaaac atggtagaga tactgagtca ttggacatta
    76141 ctatacgcct gacattggca cgtcagaatt tacatgtttt agtttgcgac aatggtatcg
    76201 ggatgtcgtc atctcgcctg caatatgtac gccaatctct taataatgat gtatttgata
    76261 ctaagcattt gggattaaat catttacaca ataaagcaat gattcaatat ggttcacatg
    76321 cacgacttca tattttttca aagcgtaatc aaggtacgtt aatttgttat aaaataccac
    76381 tttcaagggg gaatgtagat gtttaaggta gttatttgtg atgatgaacg aattattcga
    76441 gaaggtttaa agcaaatcat tccttgggga gactatcatt tcaatacaat atacactgct
    76501 aaagatggtg ttgaagcatt atcactaatt caacaacatc agccagaatt agtaattact
    76561 gatattcgta tgccacgtaa aaatggcgtc gatttactca atgatattgc gcttctagat
    76621 tgtaatgtca tcatattatc gagttacgat gactttgaat atatgaaagc cggcattcaa
    76681 catcatgttc ttgattattt attaaaacca gtagaccatg cacaattaga agttatttta
    76741 ggaagacttg tccgtacctt attagagcaa caatcacaga acggccgtag cttagcatct
    76801 tgtcatgatg ccttccaacc actattaaaa gtagaatacg atgattatta tgtaaatcag
    76861 attgttgatc aaattaagca atcttatcaa acgaaagtga ctgtttcaga tttaattcaa
    76921 catatcgatg ttagtgaatc gtatgcgatg cgaacattta aagatcatgt tggtattaca
    76981 attgtcgatt atttaaatcg ctatcgtatt ttacaatctc tgcaattgtt agatcgacat
    77041 tacaaacact atgaaattgc agacaaagta ggcttttcag agtataaaat gtttagctat
    77101 cattttaaaa aatatttaca aatgtcgcca agtgattatt gtaagcaagc taaatagatt
    77161 agcacataac taatgattat ggcgcctaca ttttgttcta tgaaaaagcg gactgataga
    77221 gaagttttca cttttctttc agtccgcttt ttagagagtt taaatataaa acaatactcc
    77281 ctacaatatt gacaccgcta tatgtcttta ttgtaaggag taaattcatt gagtcaccct
    77341 aagtcgggca aataaggata cttcataaca gggaattatg atctgccccg agacatagag
    77401 atgatatatt tgcaagggta gaagcagtat ctttcatctc ttcacgcaca tgccgtcggg
    77461 gcaggattgc caactatatt gcaatagatt ggcgatactt ttaatccgat ttatattaaa
    77521 tttttaaact tctaattttc ttttcttcat agaaagcaac gattcctaat agaatcatgc
    77581 ctaggaataa tgcaacatag aagacgatga aaacatctgt ccatccactt aatgtatatc
    77641 caaagatgtt taaaccgtta cgtgttggat cagcaatagc cgccaaacca actttcgcca
    77701 ttgagtcacc gaatagatac gcgaatgaac ctgtcattcc gtttgctaca ctgatggcat
    77761 ttttaggaac aaaaccagtc aatgatacac caattaataa ttgcggacca aagattaacg
    77821 cacctaatgc aaacaatgaa atgttaacca tcatgacact tgtagcattt gtgtagaata
    77881 agacaacaaa tgtaatcata aacatacagc caatagctac aattgcacga cgacctttta
    77941 ataagtctga tacgtagccc cataataaac ttgcaactaa tgcaccaatt tcaaagtaga
    78001 atatcgtatt aactgcatcg cctttactaa agtgtaaatg ctctgacaca tataacggtg
    78061 cccagttatc aataccgatt cgtacaatgt atacaaagac gtttgaaaca catagaatcc
    78121 atataacagg atttcccagg atatattttt taaagatctc ccatttcgtc ataccttgag
    78181 aatcaatatt ttctttatcg accggctctt cccaaatttc ttcagcacga ttccatccta
    78241 attcttctgg atcatctttt ccgataaata atgttgcgat accaataagt aatgcaatca
    78301 ccgatgggaa aatgaacatc cctataacat ttccatggaa gaatacatta gcaccccaaa
    78361 gtgcaacacc acctgcaatg gcaccaccga tattatgtga tgtattccaa aatcctaagt
    78421 atcggccacg tttcgttctt ggcgcccatc ttgaaatcgt tgaataactt gcaggtccac
    78481 caactgattg gaacaccccg ttaagtcccc aaagtacaat taataatccc attacagaac
    78541 caaagtaact taaaacaaat cccataatta aaactgtaat cgcagataag ataagtaaga
    78601 acgagataat acgttttgtg ttacgtccat cgacaaaata tccaagtaat gttttcccta
    78661 aaccgtacgt gatactaaat gctaatccga tataaccaag ttctaatgta gataatccaa
    78721 tttcctcttt taaaaacggt tgggccgcct taaagttgtt tcgaattaaa tacatagcca
    78781 tataaacaaa gaacactaca aagaaagctt gcatgaagtt tctaagccat aatttacgtt
    78841 gtaccgataa tggaatgcct ttgttcggaa tcttatggat atcaaaaaag ttcatctctg
    78901 tcacctcaat cattttcgtt aagccaaata tatcacgtcg gtgtaagcgc ttaatatcct
    78961 taaaattatt aaattatcca aaatactgaa cataaacaca tacttagaaa catatttatg
    79021 tactaaaatt aataaatagt taatagtatt tgacaagttt tatctataaa atactttatg
    79081 ttgtcaaaat caacgcttat acatatgaca taatgacgga ggacatcatg attctatcta
    79141 tattacttat ctttttctgt atcagacttg tcagcttaaa gatatctatt aatcactcaa
    79201 aacaattaaa agcagacggt gcagttgaat atggcgttaa aaattcgaag tttttagcaa
    79261 taacacacgt tttaatttat gtattggctg gtgtagaggc atttattaat aaagatacat
    79321 ttagctttgc aaatggtatt ggcttagtta tattaatctt tgcttatatc atgttattta
    79381 tggttattaa aactttaggt ggtatttgga cattaaaatt attcatttta cctaaccatc
    79441 ctattattaa atctggatta tataaaatta caaaacaccc aaattacttc ttaaacatca
    79501 ttcctgaatt aatcggtgta ttattattaa cacacgcaac atatacaact attttattag
    79561 taccgtatgc gtatttctta tatgtacgta ttaaacaaga agagaaatta atgaatattt
    79621 aaaaagatga aagcctgtca tcacattagt cgacatcgac gtccatcttt aaagtgcgtt
    79681 ctgaaatatt atattcagaa gcctttaaag tatgtcgtgt ctatgaccat tgtgacaaca
    79741 ggcttttttt attatcatat acctcactat cgaaaaggtt atatactctt ttcaatggtg
    79801 aggattgtta ctgtgaatgg gtatgaccat cgctaaacac ttatataaag tacaccttct
    79861 ttacaaacaa tgacatgatt taaggtgtga aatttttggc aatggcttgg cgacatatgc
    79921 attcattcaa cactgccacc agtcttactt cagacaaact tcagactaac ctcgagttcg
    79981 tattatgccc accacatgtc tgctggcttg tcgtaaatat taacagattt caaagtttga
    80041 caagcttttt ggaaaccttc ttctactgac ataataggat cttcatgttc aatacttaat
    80101 acataatcat atccattaat aataagttga cttatgatat ctgcccatac atatggacta
    80161 tgtccataac caactgtacg gaatgtccat gctcttgtcg caacgttacc atatggttgc
    80221 atatcagtta gaccatacat atttacattt tcttgattaa tatacgtatc tttagcatgg
    80281 aagtgatgaa ttgcatttgc ttggcctaat atgcgaatcg cagcaattgg atcaatacct
    80341 tgccaccata aatgactagg atctaagtta gcaccgatat attcatttgt agcctcacgt
    80401 aactttaaca tcgtatatgg tgtatgaact aaaaatcctg catgtaactc tatagcaatt
    80461 tttacatctt gctcttttgc aaactcagct aaatcttgcc aatatggtat caacttttca
    80521 ttccactgat aatcataaat ttcagagtag gctgttggcc aaggtgtaac aggccaatta
    80581 ggctttttag cggtatcatc tgaccctgca atgccagaaa atgtattaac aactggcacg
    80641 tctaatagat ttgctaaacg gattgtttta cgtaacgttt catcggcttc tttcgcttct
    80701 atcggatctg gagaaattgg attgttatga caactgaaac cacttatttg taagcctctg
    80761 tctgtgattg acttcataaa tgcttgtcgc ttgtcttcat tttctaacaa ctcatctaac
    80821 ttacaaaatt tatctcctgg gttaccacct gttccaactt caatcatatc caatccagat
    80881 tctgcgacat aatctaacat atcttcaaaa tttttatcgt aaaataatac tgaaaataca
    80941 cctattttca ttgaaaagca ctccttcttt ttatattgag aattttgtat tatatataat
    81001 aatcattaaa gttgtatgct cttgttatca agatcgctac gataaatcgc ttctataagg
    81061 gcatttacat tgcgtgcttc ttccggtttc accacaatct cttctatacc taaacacgca
    81121 ttgacaaagt tacgcgcctg tctctcacca gcaatgtctt cgttatgctc aacattagct
    81181 ttgctttcaa aaatagttcc aaagcggggc tcatatattt caaatggaaa taaattgata
    81241 ccgccatctt ctcctgataa actaacgtgt accttatctt cctttatatt tgcagaccac
    81301 gaacattcaa actgcatgct tgctcgattg gcaaatgtca tataactagt aacatgatca
    81361 tcgacatcaa atttagtgtg atcaaatgtt ccccaatcat taatttgatt cggttgtttg
    81421 ctcaattgat tatatgtttt tcctagcact tcatgcggca ccatatcttt acctaatagc
    81481 cacaaagata agtctaacaa gtggcaacca taatcgatta aactaccgcc accttgcaac
    81541 gctttattgg taaaaacgcc ccacccaggt actttacgcc tacgcatcgc ttgtacacgt
    81601 gctactaatg gtttaccaac cacacctgct tcaattgctt ttttagcagt catagcgaca
    81661 tctgtgtgac gataatgata agcgacagtt aataatttgt gatttttatt agccgcttca
    81721 atcatgcgat cacactcttc cgtcgtcatt gccattggct tttcgcataa gacatggaca
    81781 ccatggttca atgcttctat agaaagatca gcatggaatt tattgggtgt acaaatgacc
    81841 accgcatcaa caagtttaaa cagctcgcta ggtgtctcaa ctgcctgagg tatattaaag
    81901 cgcttcgcaa catcaatcat ctgcactgta ttaatatctt gtactgcaac taatgagact
    81961 gtgtctttga gtttcagcaa tgctggaata tgacggtctt gtgcaatgcc accaacacct
    82021 atcacaccaa cttttaattt tgtcatgatg tgcctcctta ccgtatgatg ttattcaaag
    82081 taaattgctt tgcctgattt tgcagactga taaatcgctt caagaatttt tgtaactacc
    82141 attgcttgtt ccggtttcac aactggttca gtatcattta caactgcatc aatccaagct
    82201 tttgcttctt cttcagcttc atccatttca ttaccttcat aaaagtcgac gcctttgttt
    82261 tccaattcaa cgtgtttggt ataaagtgtg cccatatctt caccatgaat acgtagacca
    82321 tctttcatat cagcacctgc tttcgttcct gataatgaac attttgcctc atccacttct
    82381 aaagaattaa tcgcccaagc ggattctaaa atgatcgtcg ctccgttctt cattttaata
    82441 aagccaaacg cagagtcttc aactgtaaat tcatctggat tccatgaacc ccaagcgttt
    82501 gccgcatcat gctgcttatt taatttatgg aatgttgaac ccatcactga ttctggttca
    82561 taattatcca tcatccataa cgttaaatct aatgcgtgcg taccaatatc gattaaaggt
    82621 cctccacctt gggcttcttc gtttagaaag acaccccatg tcggtactgc acgacgacga
    82681 atggcatgtg cctttccgaa gtaaatgtct cctaagtcgc cacgttgcgc tgcttgatgt
    82741 aaaaattgac tatctggtct gaagcgattt tgataaccta ttgttaattt tttacctgtt
    82801 gatttagctg tatctatcat tttttgagct tctgctgtcg ttttagccat tggtttttca
    82861 cacatcacat gcttaccggc atgcaaccct gctacagtaa tttcacaatg cgagtcattt
    82921 ggcgtacaaa catggataac atcaatcgtg tcatctttta acaatgcttt gtaatcatca
    82981 taaacctttg cattgtcagt tccgtatgct tctgccgcac tcgctgcttt cgaaatgtct
    83041 acgtcacaaa atgcgatcat ttcaacattt tcaacttttt gtaaacttgg catgtgcttg
    83101 ccattcgcaa taccaccaca cccaatgatt ccaactttaa tcgtcatcat aacgtcctcc
    83161 ttttaatctt tatcgtcatt agtggttctt tatcaattct gccccactcc taatttcaaa
    83221 ctaacctttt gtcgcacctg ttgttaaacc tgatactaaa tagcgttgca agaacaagaa
    83281 tacgattgct ataggtactg caatcataat tgtccctgct gcaaacactg tgaaattatt
    83341 tgcatactta tcattaataa agttgaacaa tccaactgct aatgtgaatt tttcaggact
    83401 tcttaatagt attttaggta atataaagtc cataaatggt cccataaaat tgaacaaagc
    83461 aacaactgct aaaatcggct tagctaatgg aagcataatt tgtaagaaaa tacgcatatg
    83521 ccctgcacca tcaattttgg cagattcatc aagttctttt ggaatcgtat cgaagtaacc
    83581 tttcactaaa aaggcattca tcggtattga tccaccaata tataccagtg ttagtccaaa
    83641 taaagaatct aataaaccaa ttgtatttag caaaatatag attgcgacca ttgccattaa
    83701 tacagggaac atttgtaaaa tcaaaaatgt aatcagcccg tatttacgac caacaaagcg
    83761 atatctagaa aaagcatatg ctgttaacgt gacaaatatc acactaaaca gtgcatttgc
    83821 agatgctacg ataagcgtat ttttatacca agtcaggtat tgactactgt catcgaatag
    83881 taagaatgca taatttttaa atgttgcatt gtctggtatc attttggcac catacaagtt
    83941 cgtacctgga ttaagggaaa tgccaaatgt ccacagtagt ggatataaaa tgatgacaaa
    84001 catcatcgct ataaaactgt aaataccgat tgcttttaat atgtttttct tctttgtcat
    84061 cttataaacc tccctcatct ttaaacgtac ttgtacgtct gaattgaata aatgcgacaa
    84121 tagcaacaat aaatccaata attaatgaca caactgcacc catgttgaag ttgttaaact
    84181 caaatgtcag attatacacc caagatatca agatatctgt actaccagca ttctgccctg
    84241 acactggtgg accgccttta ttaaatagat aaataagatt aaaattattg aaattacctg
    84301 catattgcat aattaacaat ggcgctgtgg cgtaaatgac atgcgggaat gtgatgtttc
    84361 taaacttttg ccaactagac gcaccatcca tatctgctgc ttcgtaccaa tctgatgaaa
    84421 tactttgcag tactccagtg aacagtgcaa agacaaatgg gaatccaagc catacttgaa
    84481 tgccgattaa tgccactttt gcccaaaacg gatcacttaa ccatgctggt gctacaccta
    84541 ataaaggttg caaaatatca ttatttatcg caccaaattc atcattaaat aacgctacaa
    84601 atattaaaat tgtcacaaat gatggtacag cccaaggtag gattaacaca gtacggataa
    84661 atttcttacc tttgacgaca gggtgattta caataattgc caaaaacagc cctaatgcaa
    84721 tttgaagtgt cgttgcaaca agcgtccata ctaatgtcca agtaataaca ctgaaaaatg
    84781 ttttgcgcca aacgccaatt gtgaataacg ttttaaagtt atctaaacca acccattcta
    84841 atgtgtgtct cggaggtgcg ttgtataaat tgtagtttgt aaatgctact ccaaacataa
    84901 atattaatgg aaatacaact acaaatatca ataagaatgt acctggtgag attagtaagt
    84961 atgggaacgt cttgtcccat gttgccacca tacgcgcctt cggatccttt atttcctcat
    85021 tgcgattaaa tcgttcagca ttacgatatg catctaaaat attaatgaca tatagcatga
    85081 ttgcgaaagc aacgagtaag atagaaataa taccttgtgc aagtaagaca cgagaatcgt
    85141 ctaacttagg tactgtccct aatgtgaaca atccccaaaa accaatattt aaaaagctat
    85201 aaaatacaga aataaaactg atgaaaaaga taaaaaatat cgtaccttta atgggtcttt
    85261 tattataaaa ctgtcccaaa ccaggtataa cagataataa tgccgctaat ttagggttac
    85321 gtttcgtcat aactaatctc ctttcttatc attttgtgat ggatgaagaa tcttaatatt
    85381 ttgcgttata tcattcgtcg cctcatctaa cgcttgttta ggattcttac catttgagat
    85441 aaatatgctt gcattgccca tcggttccca aacttgtcgc atttcaggaa tattaggcat
    85501 cggttcagca tgacgtgctt gcttttcaaa cacttttaaa tttggattag atgatttcac
    85561 gtcaacacgt ccagtaattt cgctcatttc atctgtatat ttttgtaatg tatctttact
    85621 agtgatatac agcattaaat ctttagccca atacttatgt ttactatatt cagataaata
    85681 ccaaccacgt acaccgagaa atggtttcat aggtttgcca ccatctgtag gtaatgttgt
    85741 tactcctaaa tctttaccaa acgtttcttg atattcatta atgttccacg gtccagtgac
    85801 aaattgtcct acttttcctt ctttaaaaag accaatcatg acatcatgtg ttgctgcctt
    85861 aggaagatac cctttgtcgt accatttttg taatcgttca gcatttttga cgacatgttt
    85921 tgaatttagt cctagctgat gaatatcata ttcactgcca tttttcttga aaatataatc
    85981 atcattgccg aataaaaacg gataattaaa atagaaattt ttagcatcaa ataacatacc
    86041 gtattgtttc tttttactat cagttagctt ggcagcatta gcttcaactt cttctaacgt
    86101 ttgcggtgca tttttcacta attttttatt atagaaaagt gcggttgttt ctacgatagc
    86161 tggcaatgct agttgcttat tgtcataatt catcgcttta agtgcttgct tattgaaacc
    86221 tttcaactca tcttttgata atttgatttc agcagctaag ccttgtagat aggcacttcc
    86281 agtattatca tgtgctaaga aaaagatatc tggacctttt cctgcaggag cgtctagcga
    86341 aatattttct agttgatcat tttgaccaat atttacaagc tttactttga tgccagtttt
    86401 tttagtatat tgatccgtaa tttttttata aaacgccatt tgcttgtcgc catccaccca
    86461 catcgtaagt tggttaggct tgtctttaga attatcttta ttcaatgctt tatcaatatc
    86521 ttctttcgaa cgattagggc cacatgcagt tacgattaat aacattacca cggctaacgt
    86581 gatacatttt aaaattttag acatgaatac tcccccttag acgatacgat ttcctgtttt
    86641 ttcatcaaaa aagtgacact tattcatatc aaatgctagt gtaatcttgt cgttcgtcat
    86701 cacttgggtt cttgaatcta atttagaaat caattccatt ccttggaatg tactatgtac
    86761 catgatttct gaacctaaca actcggatac aactacttca gattcaaatt gtgtctctgg
    86821 agaagtttga ataaatattg gttcttcatg aatgtcttca gctcgaatac ctaaaataat
    86881 ttccttgtct aagtagccag cagcttttaa cttttcaaat tttttattat gtaatttaaa
    86941 atgatgtgtt cctaccttca atccgtccat ttcaactgta gcattcaaca tattcattgc
    87001 tggtgagccg ataaattgcg ccacaaatat gcaattaggg gcatcatata tttctctagg
    87061 tgtgccgact tgcataatgt cgccatcttt caaaacaaca attcgactag ccatcgtcaa
    87121 tgcttcagtt tgatcatgtg taacataaat tgtcgtagta ttaagtcgct tatgtaattt
    87181 caatatttct gtgcgcattt gtactcgaag cttcgcatca agattcgata atggttcatc
    87241 cattaaaaag actttcgcat ccctaacaat agctctgccc aaagcaacac gttgacgctg
    87301 tccaccagat aacgcttttg gtttacgacc aagatactca gttaatccta atatttcagc
    87361 tgcttcattg actttttgtt caatctcttt tttatttact ttacgtagct ttagcccaaa
    87421 tgccatattt tcaaatacag tcatatgtgg atataatgca tagttttgaa ataccatcgc
    87481 aatatctcta ttctttggtt caacatcgtt catgcgttcc ccatcaatat aaaaatctcc
    87541 agatgtgata gactctagtc cagcaaccat tcgtaatgtt gttgatttac cacatcccga
    87601 tggtccaaca aatacaatga attctttgtc agtaatatgt agattaaaat ctttcactac
    87661 agtattgttg ttatcatacg tctttttaat atgctctaac tttagttctg ccatgttatg
    87721 cctcccatac tttgtttaca gtttgattgt gcaatacact ttgtgaaaac gtttgcacaa
    87781 atacttacat aaatcatata ttcagtcatt attaatgtca atcataaatt gtaaacgttt
    87841 acattactgt cagaattaaa cttttataca gaaaattgat atagtacaca actattttct
    87901 agtgtgacaa taatgttttt ttatgtgcga tatttcactg ccaatgctaa caaccttgtc
    87961 ttacatttta agtaatatct aaatcaaaca agtatgactt agcattacga ttttcattga
    88021 aaaaagcaac cattatgtaa gtatcatact cacacaatga ttgcttaatt ttttagactg
    88081 cgggcactct tctataacta caaatcatat aggctacgtt ccccatcagg taactgctcg
    88141 ataaacggtt taggatcttc tgcatatgca ttacctacgc cacccttcat tctttgaaaa
    88201 tgtaaatgtg cgcctgtcgt ttgtttacct gtattgcctg aatatgcaat aatatcacct
    88261 gctttaactc gatcacctac tttgacatta tatttgtcta agtgtagata ccactggtga
    88321 tattctccat tgtcttcggc aatctgtaat accttgccgc ctaattcatt attaaagata
    88381 cgtgttactt taccattcgt cggcgcttta attggtgtac cttttggcaa tgcaaaatca
    88441 atgccataat gcttaccatc aaatggtgaa tgttgatatt tgccaaaagt ctcagtaatc
    88501 ctactccctc taaaaaagtc ttcccatttt gagtgtcctt gtcctttatg attttgtgtc
    88561 aatttatcgg tatattggtt aaaccatttt tgaatgtcat ctatataaat aatcgtaaat
    88621 aatagtgaaa gaaaaatgat aattgttgcc aaaatacgtt ttggtcgctt tgtcatagtg
    88681 gcatccatcc ttcatatatt ttgggtatta agtatatatt ctaaatcaac tatttcataa
    88741 ttaaatgcac tcatacttta gtagtactgc caaatataga tgaagaaaat gatggtaatt
    88801 tgaatatttt gattgatatt aaattttata tcgagtataa taattatact taagaaaata
    88861 acagaaacag aggagaattt tcaaatggca aaagtattat atattacagc acaccctttt
    88921 aatgaactgg tatcaaattc tatggcggct ggtaaagcat ttatcgaaac atatcaacaa
    88981 caacatcctg atgatgaagt gaaacatatt gatttatttg aaacttatat tccagttatt
    89041 gacaaagatg tattaactgg ttggggaaaa atgagtaatg gcgaaacgtt aactgatgat
    89101 gaacaaatga aagtttcaag attgagtgac attttagaag aatttttaag tgcagataaa
    89161 tatgtatttg taacgcctat gtggaacctt tctttcccac ctgtagttaa agcatatatt
    89221 gatgctattt caattgcagg taaaactttt aaatattctg ctgaaggacc acaaggttta
    89281 ctaactgaca aaaaagtatt acacattcaa tcacgtggtg gatattatac tgaaggacct
    89341 gctgctgatt ttgaaatggg tgaccgttat ttaagaacaa ttatgacatt cttaggtgtg
    89401 ccatcatatg aaacaatcat tattgaagga cacaatgccg aaccgcataa aactgaagaa
    89461 attaaagcaa ctagtattaa taatgctgaa aaattagcaa caacttttta aatttttaat
    89521 tacactgtgt gactcctcaa cgtcatgcag ttttttattg tatctctttt ccgcttttta
    89581 taaatatcta ttattttcat aaatttaaaa tttgatattc actttaatac tgatgtaaat
    89641 atttttcaaa atatattatt atagtgttaa tgaagtattt tgagaaacgg tgggaatgta
    89701 tgaaagcaca taaaattttc tggttaaact tagcagcaat tattattatt tcaattgtag
    89761 tcagtggcgg tatgtttttg gcaatgaagt gggaacaaat tcatttgaaa gatggtctta
    89821 aaaaagtact aagtacgtat cctattaaaa acttagaaac gctttatgaa attgatggtc
    89881 acgataatcc ccattatgaa aataatgatc aagacacatg gtatatagaa tcctcttatt
    89941 cagttgttgg atcagatgag cttttaaaag aagaccgtat gttgttaaag gtagataaga
    90001 acacacataa aataactggt gaatatgaca caactacaaa cgatagaaaa gatgctactg
    90061 actcgacata caaaagttat ccagtaaaag tagttaataa taaaatcgtt ttcacaaaag
    90121 acgtaaaaga tcccgcgctg aaacaaaaaa tcgaaaacaa tcaatttttg attcaaagtg
    90181 gtgatttaac aagcatttta aatagcaatg atttgaaagt cacacatgat cctaccactg
    90241 attattataa tttatctggt aagttgtcga atgataatcc aaacgttaaa caattaaaac
    90301 gtagatataa tattcccagt aatgcatcaa caaaggtgga attaaaggga atgagtgatt
    90361 taaaaggcaa taatcatcaa gatcagaaac tttattttta tttttcaagt cctggaaaaa
    90421 accaaattat atacaaagaa agccttactt ataataaatt aagtgaacat taatacttat
    90481 gatgtaatta tagaaataac caaatcattt attatcgttt aacatattaa aatcacacat
    90541 tataaaaacg cctcacatca ttcatttaat tgtaccgaat cacatcaagt tagattttag
    90601 actaactatt gtggtgtaca tcaaaaacga atttgtgggg cgttttatat tttacaaagg
    90661 cgactagcgt ttcttataac aacttcaaca ttactacact caagcatcac tctaaagttt
    90721 gaaatcgaac cctttcgttc aacaaaaatc aaaatccact tcaaactata tatcaaatac
    90781 ataaattatc ttgtgatact atctcgatca tatctatagt atgcatttgt gtttgctttc
    90841 actgaatgat atgtttcatc agttaagtat aaactgtcat cctttaaggt aacttgataa
    90901 cctttcttcc gtgccaacca ggcaatatct atataatttt ttccggcgat ttcataactt
    90961 cttaaatctt caatatgcac actaacttca gggaaaatga ttctaataac actttcatca
    91021 acccaatatt tgtcatgcat ccaccgcact tgttcagcat ataatggcaa ctgcatatca
    91081 ttgaaatata ctcgatgggt gtcattatcg tatattttcg gactaggtaa tggttgtttt
    91141 ctaattgata atacatcgcc acctatcact gtgccttccc tcgtatcatc agcacctccc
    91201 gacgcgtcac gtgtattcaa gtcaacctgt aacccatgta catctccaat ataggcatct
    91261 ggtttatgtt ccattgcatg tccacgtgca atcaatgcta atattgtaga ttgtgaaaat
    91321 tgaggctccc attcaatgcg attaggatgg ctactataaa ttctaggttc atctatagcc
    91381 tgctgaatat ccatgccaaa cactaataca ttgattaatg tttgcgcaac actagcaatg
    91441 atacttatgg caccaggtgc acctactgtt aatatcggct tcccgtgatg catcacaatc
    91501 gttggagcca tgttacttag tggtcgttta tatggtgcaa tttcgttaat accaccatct
    91561 actacatcaa agccatccat tgtcgtattc aataacacac cgtagcctgg aatcgtgata
    91621 cctgaaccat aaatcatacc aattgatgtc gtaaatgaag caatattacc ttccttatca
    91681 atcacacaaa aatgagttgt ttcggtatga ttttcttcaa catctgtatg actaatgcaa
    91741 tcagacacaa caccatgctc tatatcaata tttgctttat tgctattaat gagcgtactg
    91801 cgtgctttta aataatcgtc atcaattaat gactgtacag gcacctcatg aaaattatca
    91861 tccgccaagt attgcgcgcg atcactatat gctaaatgca tcgcttgtat caaatgatgc
    91921 aagtaatcga cagatcttgg acccatagat ggtaaatcga catgttctaa taacttcaat
    91981 atttgaatga ccgtgatacc gccagaacta gatggtccca ttgaataaat gtcatagtct
    92041 ttaaatgtcg cactgattgg cgctttaatc tgaatgtcat aattggctag atcctctaaa
    92101 atgattgtcc caccacatgc tttaacaaca ttgactaatt gtttcgcaat gtcaccttta
    92161 taaaatgcat taaacccttg ttctcttaat atttgaaatg tcttacctaa ttcgggttgt
    92221 acaatccaat caccttcacg ccaatattga ttttcatgcg taaatacttg tgccgtttca
    92281 tgatactttg tcaatcgtgc gtgttgctgg cgcgaatatt tttcagtagc ccaattggct
    92341 gcatgacctt caatggctag ttcaattgca ggattaatta aatcttccaa tgacaattta
    92401 gcataacgct tgtgaatata atcaaacagc tttggaattg ctggcacagc gacagtttta
    92461 ccatgtgtag tcatatcaaa aaatgattta tattcgcctg aatcatctag ataaaattgt
    92521 ttgtctacat gttcaggtgc tgtctcacgt gcatcaaacg cagttatact gccagtactt
    92581 tgctcataat atagcaagta cccgccacca ccaatacctg atgcaaatgg ttctaccaca
    92641 ttcaatgcca gttgaattgc aatcacggca tccatggcgt tgccaccttg atctaataca
    92701 tccttaccaa ttttagccgc aagaggatgt gatacggaaa ttaacccttc tttagatgtt
    92761 tttgtctgtt tgtcatttaa gttaatgacc atactatatc ctcctacttt ctgttaaata
    92821 tttaaaacat tattgattaa tggctttttc tactttttct aaatcttgac gttgctcgtt
    92881 accagtatcg acaagtggtg taatcggtga tgcaatttta aatttatcgc cacgataaaa
    92941 cttaataaat tgatcctgat ctatcgcatt aactactgct tgtctcaagt ttggatgcgt
    93001 cttaaatata ccttttttaa tatttagcat taaaaagact gacttgcgtc catttttgcg
    93061 aataatgctt aaatttttat ccgacttaat taaatcaaaa tgtttttgat tcacatctgc
    93121 caacatatca attgaatgat ttctaagttc tgacaatgca ttattcggat caccattaaa
    93181 cttcaatgta atatttttaa ttttaggtga tccataacta cctttttctg tttcgttgaa
    93241 tcctggatta cgttgaaacg ttgcttgata tgcatttttc tgtgtcataa tgtatgcgcc
    93301 acttgcataa agcgcatttt ttccatctga atttgcagga attgtactgc tatccccata
    93361 tccttttgga tattcttgat ttacttgatt aacaaatttt ttagataaaa tgcctgccga
    93421 agagtgtgtt aagtaattta cctctcgagg catcgattga tctgtcgtaa ttttaacaat
    93481 ttgataaata ccgtctttat tatttacttt ttgaccatct gtcgttaacg atttgacgtt
    93541 ataagcttta atcaacttat catagattga tttatcatcc ttgtctttct ctttacgcaa
    93601 ctgatcgatg tcctcatctt ttaatatctt gatgtcattt atatgtttgt gcatattgta
    93661 agtattattg ttaggcacag actttttatc acgtgctcta tctaaagaaa acttaacatc
    93721 ttcagccgat acacgctctc cagtattacg tgcttgtcca ttgaccactt tcgcaaaata
    93781 atcatcatct cttaacaaga aataaaatgc tttattgtcc ttattcacag cataatcacg
    93841 acttaacgaa cctttcgttg ttaagtgatc attttcatct aataataata accttgtgta
    93901 catattcata ttaattgaat atactgacgg cgcaattgaa cgtattggat ccaatgtagg
    93961 aatttcacca tcttgttgtg tcatcacaag tggccgcgta tctcgttctc tactattgtt
    94021 gtaatcaaat tgttgccata ttaatgcacg tgaatttggc aatccaacac tatttttatc
    94081 taacacttta ttgtcatata ctaaattctt ttttgatcca tataaaggcg ccatataccc
    94141 tttatcaaat acaacttcat cttcaatttg cttatatgtt tgtttaacat ctgcttcatt
    94201 ttgagtagaa gctttattta acaactggtc tacatgttta tctttcaata aactatttga
    94261 tcctgtagaa ctaaataatg ccgtcatagc atagttcggg tcaccaaaca ctgtcatcca
    94321 gtcatcaatt tggatatcat aattgccggc ttgacgttgt gtacgatagc taccataatc
    94381 tggttggata ttcatcttca cgttaaatcc tgcattttcc aattgatctt taacgatatt
    94441 catatcattt tcataacttg cttgtcctag gaaatgtatt gttggtcgct cgcctttcac
    94501 ttcaactttc gatgactttt gagccacttc tgatttcgta gggacaccac aaccacttaa
    94561 taccaacgct aaaactataa ttgcgatact aatgattttc ttcacatcta tccctacctt
    94621 tttaatgaat tcttggatct agtgcatcac gcactgcatc acctataaaa ttaaatgcta
    94681 aaacgacgaa cataatacaa acaccaggta caatagctaa attactgtgc gtttccaagt
    94741 agttactacc ggtacgtaaa atgttgcccc attcagctac atcaggtgca acaccaagtc
    94801 ctaggaaact taaactactt gttgttaata caaccacacc tatatttaat gaaaaacgta
    94861 caatcatagg cgcaatcgca ttcggtaaaa tataacgcca tatgatattc caagtgtttt
    94921 caccagtgat acgtgctgca tctacatatt ccatgcgttt aatttctaaa acactggcac
    94981 gcattgtccg tgcaaatgat ggtatattac cgatacttaa agcaataatt aaatttggaa
    95041 tacttgctcc aaatgatgca ataattgcca ccgctaacaa taatgatgga attgcaaaca
    95101 ctacatctaa aattcgcatt attaaattat caatatgatt aaaataacct gcgatagtgc
    95161 ctagtaacac accaaaaata actgcaataa ctactgaaat aattgaaatt gaaaatgtca
    95221 gcttcgttcc tacaactacg cgtgtaaata agtctctacc gaaatcatca gtaccaaacg
    95281 gataggctag actcggtcca tgtaacagtg cattgaactg atttttagta gccaatgtcg
    95341 tatcaaatgt aaattgtgac acaattgata atgtcagcat gtagactaaa ataagtaacc
    95401 cgataatcgc aatacgatgt ctagtagttt ttcgtataaa cgattcccac ccgttataac
    95461 tatgtatttg cgatgtacgt tggtaacgtc taatacttac aaacattaat aatgtaaata
    95521 cgttgcctgt taatgccatc aacaataaca acacttcgac gatacgtcgc cataggtcat
    95581 gatgcttcca tgtttgttcc gttgttaaaa tgataattaa aatgatggtt aaaatgatta
    95641 gcaatgtttc agcaatatag aacgtatcgg ccacataacc tttaaaaaga tttaatgcac
    95701 tcgttaacat aactaaaata taagttgcta tagcataact tgcgaatagt tttaaggaag
    95761 ctatctttgt tgtaagtttt accatatgcc tcacttcctt tcgttaattt cactacgtaa
    95821 ttttggatcg attaaagcat aaaatatatc aataattaag tttgctaaag atattacaat
    95881 tgatatatat acgaccccac ccatgactgc tgggatatca ggtattagtt gtttttggac
    95941 gatataacga ccgataccat taatgttaaa tacttgttcc gtcactgctg aaccgcctag
    96001 taactctgcc actagaagac caactaacgt tacaattgga ataatggcat ttttcaaaat
    96061 atgtttaata acaacttgtg tcgtcgataa tccttttgca taagcagtta aaacataatc
    96121 gctgcgcatt acttcaagta cagaagacct tgtcatacgc gtgatagaag cagcaatact
    96181 tgttccaatg acaagtacag gtaaaatcaa cgatattgga tgttctggca tataagatgg
    96241 tggcaaaata tccaatttca atgagaacgc taaaatgaat aatagccctt gccagaaact
    96301 tggaatagat aaaccaatta atgcaattat cattaacgtg atatcaagcc aactatttcg
    96361 cttcatcgca ctgataatac caattggtat tgcaataatt aatgccacaa ttagcgctaa
    96421 tactgcgaca attattgtaa ttggaattct ttcgccaact gctttagtca caacctcatt
    96481 ccctttgtaa gtcgtaccta agtcaaaggt aaaaacaccc ttgatggtat cccacaattg
    96541 aataaaataa ggttcgttaa gatgatgtaa tacattgaat tgatgtatct gtgcctttgt
    96601 tgcattttgt cccagtatgc tataagccgc atcaagcggt gaaaaataca gaatggtaaa
    96661 cacactgaca ataacaccaa tgatgacaat cacagccatg acaattcgct caaaaatata
    96721 tctaactaat ggctgtaaat aaatagtcaa taagatgaac atcggcaagg ccaatattac
    96781 tttgatcatg atgaacttat gaaataataa attttcaaag tatgttgaaa aatgtgcttg
    96841 ttcaatattc tttgaactcg tattagaact ttgtgccttg aatattttta atgcttcttt
    96901 atgtatttgt gtggatgact tttgctgcga taaatattta tatttttgat gtaacgctcg
    96961 ttcaatttct gaaatttcag aattattagc gtaaaaattt tttctcttag cagaaaagaa
    97021 aaactttatc actgcatata aaaatattgg caagcttaat accgataata caaacttgta
    97081 aaatgccttg tgatacaacg acttaaaaga ttctaaataa gtaattatga taatcactcc
    97141 ttgtaaaata atcttgagta gattactatg atatacaaaa gtatagaata aatttacaca
    97201 tttgtgaata gggaggcaca acatcatgtc aaatttatta gaagtcaaca gtctgaatgt
    97261 acaattcaat tatgatgaaa ctacagttca agcggtaaaa aatgtctctt tcgaattacg
    97321 aaaaaaacat atcctaggta ttgttggtga atcaggatca ggaaaaagta ttactgctaa
    97381 atctatttta gggctactac cagattatcc agatcacaca ttaacaggag aaattatttt
    97441 taatgggcaa tcgttaaata atttatcaac ttcagcgtta caacaaattc gaggtaagga
    97501 tatttcaatg atttttcaag atccactctc ttcgttgaat ccaagattaa cgattggcaa
    97561 acaaattaca gaagtactat ttcaacataa acgtgtatct aaatctgaag caaagtcgat
    97621 gacaataaac attttagaaa aagtaggtat aaaacatgca actcgacaat ttgatgctta
    97681 tccacatgaa ctttctggtg gtatgcgtca acgtgtcatg atagcaatgg cattgatttt
    97741 aaagccacaa attttaatcg cagatgaacc aacaacggca ttagatgcca gtacacaaaa
    97801 tcaattactg cagttaatga agtcccttta tgagtacaca gaaacatcta ttatttttat
    97861 cactcacgat ttaggcgctg tgtatcaatt ttgcgacgat gtgattgtaa tgaaagatgg
    97921 aagtgtcgtt gaaagtggca cggttgaaag tatttttaaa tcgccacaac atacctatac
    97981 aaaacgctta atagatgcga ttcctgatat tcatcaaacg cgtccgccaa gaccgttaaa
    98041 caatgatatt ttattaaaat tcgatcgcgt gagcgtggat tacacatcac cgagtggcag
    98101 cctataccga gcagttaatg atattaactt ggctattaga aaaggcgaaa cattaggcat
    98161 tgtcggtgaa tcagggtcag ggaaatcgac attagctaag acggtcgtcg gtctaaagga
    98221 agtgtcagaa ggctttattt ggtataacga attaccatta agtttattta aagatgatga
    98281 attgaaatct ttacgacaag agatacaaat gatttttcaa gatccattcg catctattaa
    98341 tccaagattt aaagtcattg atgtgattaa acgaccacta atcattcatg ggaaagtcaa
    98401 agataatgat gacattatta aaactgtcgt atcgttgtta gaaaaggttg gcctagatca
    98461 aagtttctta tatcgctatc cacacgaatt atctggtggg caacgtcagc gtgtaagtat
    98521 cgcgagagca cttgctgtag aacctaaagt gattgtttgc gacgaggcag tgtccgcttt
    98581 agacgtttca attcaaaaag atatcatcga gttattaaaa caattacagt tagacttcgg
    98641 catcacttat ttattcatca cacatgacat gggtgttatc aatgaaatat gtgatcgcgt
    98701 tgcagttatg aaaaatggcg aaatcgttga actgaataac acagaagata ttatcaaaca
    98761 tccgcaatca gactatgcaa agcaacttat ttcagaagta gcagttattg ctaaataaaa
    98821 gtcatgcgtt gtgtaacttt atcactgtat ggtctggaat aaatcgggca acctctgatg
    98881 tgttatgtta gatgactttg tcatactaac tatattgtgc taagttaggg ctcggcacca
    98941 tatcaagttt taagtgcctt gccatgattt aagggtcaca cccatactct gggcattttg
    99001 acgccagaat aaatcccccg ccactatgtg aagtgcgggg gattatttat attttattag
    99061 aatattcaga ttttcgagtg tgt
//
LOCUS       DAPDIM010000003        88172 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000003 DAPDIM010000000
VERSION     DAPDIM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 88172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88172
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.003"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(230..922)
                     /locus_tag="RFE25_000184"
     CDS             complement(230..922)
                     /locus_tag="RFE25_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDU2815291.1"
                     /translation="MNYSPKQGVRSHGLPHDPFKSSTVPRPIGWISTVSKDGKDNLAP
                     YSQYQNLTWDPPMVMFAANQSVLGDHERKDTVKNAEETGWFVWNMATYDLREAVNLSS
                     KALPPEEDEFEYAGVTKEACIEAPGYRVKESPVHFECEYVQTIRIPTGDPVSTVDIVI
                     GRVAQVHIDDKVILDNGKLDIKSIKPIARLGYYDYTVVNEIFEMKAPAASKEELAGLE
                     GRNFDNQSDEKR"
     gene            1158..1616
                     /locus_tag="RFE25_000185"
                     /pseudo
     CDS             1158..1616
                     /locus_tag="RFE25_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226788.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1603..1905
                     /locus_tag="RFE25_000186"
     CDS             1603..1905
                     /locus_tag="RFE25_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815292.1"
                     /translation="MRTNNHITDLDAIELSSGWNYNSKLVTGKNALLSDSLLRDIKVL
                     SSNAKGDADILETELRAVINAMSQNEGKSVDALKNSTTSLKNNLTKLKEQLDKTTH"
     gene            2059..2418
                     /locus_tag="RFE25_000187"
     CDS             2059..2418
                     /locus_tag="RFE25_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815293.1"
                     /translation="MILRYATNLKLAKELYQASKPKLQEDKGMIELFEHTFGLQKELV
                     KYVGIAEATTAALYSASFINKNISRLASLSTIGILSVAAYKHFEAGQGKKGAQHALDL
                     LGLATLSLLDTFSCNKK"
     gene            complement(2503..3114)
                     /locus_tag="RFE25_000188"
     CDS             complement(2503..3114)
                     /locus_tag="RFE25_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDU2815294.1"
                     /translation="MYTFDAQSLTARENYKLLIGSIIPRPIAFVTTLNQDASVNAAPF
                     SFFNIVNNHPPMVAIAVQRAGGKRKDTALNIERTGDFVVHITDEDNVQDINETAAPLA
                     YGDSELSRTGLSLLTSTTIKTPGIKDAKMRFECKLSQMILLGDVLDGADLIIGEIVTY
                     HIDDSIYEGDFKINPHALQAVSRLAGNDYAKLGGIFTIKRPEK"
     gene            complement(3193..3669)
                     /locus_tag="RFE25_000189"
     CDS             complement(3193..3669)
                     /locus_tag="RFE25_000189"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase"
                     /protein_id="HDU2815295.1"
                     /translation="MVVVYVAGGCLWGVEAFFATIPGIIHTEAGRANGRSSKLDGPYD
                     GYAECVKLHFDDRMLTITDIMNYLFEIIDPYSVNQQGNDIGEKYRTGLYSCVDDHLIE
                     ARQFIERRKDRDQIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHISKDLLNKYK"
     gene            complement(3672..4172)
                     /locus_tag="RFE25_000190"
     CDS             complement(3672..4172)
                     /locus_tag="RFE25_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2815296.1"
                     /translation="MVLRKVIMQDLDQIIALENIGFSPEEAATREALKLRIEQIQETF
                     IVAEKNDEVIGYINGPVIKERYISDDLFKNVSINNSEGGYISVLGLVVAPNYQGQGIA
                     GRLLNYFETLAKNHHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNI
                     KKDDEV"
     gene            complement(4407..5174)
                     /locus_tag="RFE25_000191"
     CDS             complement(4407..5174)
                     /locus_tag="RFE25_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDU2815297.1"
                     /translation="MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHL
                     HPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILKGLDNGSIQGINRS
                     KYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALS
                     QLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYS
                     NDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF"
     gene            complement(5171..5863)
                     /locus_tag="RFE25_000192"
     CDS             complement(5171..5863)
                     /locus_tag="RFE25_000192"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="HDU2815298.1"
                     /translation="MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSI
                     VITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLL
                     NWSTYQDSIISTEIQDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPP
                     VNTVTDAQLFSKFTGNVVYVVNSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKS
                     ASYYAYYGTDES"
     gene            complement(5880..6542)
                     /locus_tag="RFE25_000193"
     CDS             complement(5880..6542)
                     /locus_tag="RFE25_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CapA"
                     /protein_id="HDU2815299.1"
                     /translation="MKEKFDLVKLLNILKKNIKLLLILPAICLVVSTALTFFVMPDKY
                     TASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAEL
                     NSFLKVTNQTNSQIITVSVTTGNKSESDKIVNRISKVFAHDMPKIMSVDNVTILSSAH
                     DNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQ
                     KF"
     gene            complement(7391..7951)
                     /gene="icaR"
                     /locus_tag="RFE25_000194"
     CDS             complement(7391..7951)
                     /gene="icaR"
                     /locus_tag="RFE25_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ica operon transcriptional regulator IcaR"
                     /protein_id="HDU2815300.1"
                     /translation="MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSK
                     KSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNT
                     PEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQ
                     KFGAVEESKSQFKDEVYSLLNIFLKK"
     gene            8115..9353
                     /gene="pgaC"
                     /locus_tag="RFE25_000195"
     CDS             8115..9353
                     /gene="pgaC"
                     /locus_tag="RFE25_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HDU2815301.1"
                     /translation="MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVD
                     ELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENND
                     FIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAV
                     TGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGY
                     WDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLL
                     RDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFL
                     LSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKAL
                     KRKKGGYATWSSPDRGNTQR"
     gene            9317..9622
                     /gene="icaD"
                     /locus_tag="RFE25_000196"
     CDS             9317..9622
                     /gene="icaD"
                     /locus_tag="RFE25_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular adhesion protein D"
                     /protein_id="HDU2815302.1"
                     /translation="MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIG
                     TIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES"
     gene            9619..10491
                     /gene="icaB"
                     /locus_tag="RFE25_000197"
     CDS             9619..10491
                     /gene="icaB"
                     /locus_tag="RFE25_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intercellular adhesin biosynthesis
                     polysaccharide N-deacetylase"
                     /protein_id="HDU2815303.1"
                     /translation="MKYRKLIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENS
                     ALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEF
                     LYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
                     MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKN
                     FKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAF
                     EHLIKRWDGFHEKD"
     gene            10478..11530
                     /gene="icaC"
                     /locus_tag="RFE25_000198"
     CDS             10478..11530
                     /gene="icaC"
                     /locus_tag="RFE25_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide intercellular adhesin
                     biosynthesis/export protein IcaC"
                     /protein_id="HDU2815304.1"
                     /translation="MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQF
                     YIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLL
                     TDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
                     SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVI
                     MIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQM
                     ISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGLCIGVGMILREFYIF
                     RFIIGKQPYKLNINAY"
     gene            complement(11865..13907)
                     /gene="lip1"
                     /locus_tag="RFE25_000199"
     CDS             complement(11865..13907)
                     /gene="lip1"
                     /locus_tag="RFE25_000199"
                     /EC_number="3.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK domain-containing triacylglycerol lipase
                     Lip1"
                     /protein_id="HDU2815305.1"
                     /translation="MKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNS
                     QEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLN
                     KDQLKDDKNSSLNNKNIQRDTTKNNNANPSDVNQGLEQAINDGKQSKVASQQQSKEVD
                     NSQDSNANNNLPSQSLTKEAPSLNKSDQTSQREIVNETEIEKVQPQQNNQANDKITNH
                     NFNNEQEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGT
                     KELTAKAKDDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQ
                     DLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGI
                     YKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNNDNM
                     ISSITTLGTPHNGTHASDLAGNEALVRQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPN
                     ESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKAL
                     NSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTNATDKIQ
                     KGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKVTDTKQA"
     gene            complement(14628..14807)
                     /locus_tag="RFE25_000200"
     CDS             complement(14628..14807)
                     /locus_tag="RFE25_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815306.1"
                     /translation="MKSKLSNSGIDVTVKDVEKYMNRYNEVMMGKNGEKAKELCLSLL
                     PINIIVVFTFFVFIL"
     gene            complement(15000..15632)
                     /locus_tag="RFE25_000201"
     CDS             complement(15000..15632)
                     /locus_tag="RFE25_000201"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDU2815307.1"
                     /translation="MTKYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGV
                     VCFYSRSKQRLWTKGETSGHTQLVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTE
                     VPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKA
                     FVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW"
     gene            complement(15629..16387)
                     /gene="hisF"
                     /locus_tag="RFE25_000202"
     CDS             complement(15629..16387)
                     /gene="hisF"
                     /locus_tag="RFE25_000202"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDU2815308.1"
                     /translation="MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAIYYNEAGA
                     DELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSL
                     NSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTHGGKKMTNIKVYDWVQ
                     QVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFNQ
                     TDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR"
     gene            complement(16384..17088)
                     /locus_tag="RFE25_000203"
     CDS             complement(16384..17088)
                     /locus_tag="RFE25_000203"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-((5-
                     phosphoribosylamino)methylideneamino)imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDU2815309.1"
                     /translation="MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFE
                     CVNRIHIVDLIGAKAQYAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYC
                     IVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRQLSDI
                     PLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAA
                     IIGKAAHQASFWEGLE"
     gene            complement(17081..17659)
                     /gene="hisH"
                     /locus_tag="RFE25_000204"
     CDS             complement(17081..17659)
                     /gene="hisH"
                     /locus_tag="RFE25_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDU2815310.1"
                     /translation="MIVIVDYGLGNISNVKRAIEHLGYEVVVSNTSKIIDQAETIILP
                     GVGHFKDAMSEIKRLNLNAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNI
                     SRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGADIPAIVQF
                     NNYIGIQFHPEKSGTYGLQILRQAIQGGFIND"
     gene            complement(17656..18234)
                     /gene="hisB"
                     /locus_tag="RFE25_000205"
     CDS             complement(17656..18234)
                     /gene="hisB"
                     /locus_tag="RFE25_000205"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDU2815311.1"
                     /translation="MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFH
                     SGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLAR
                     VVVDISGRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHE
                     IEAIFKAFSRALGIALTATDDQRVPSSKGVIE"
     gene            complement(18203..19216)
                     /locus_tag="RFE25_000206"
     CDS             complement(18203..19216)
                     /locus_tag="RFE25_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDU2815312.1"
                     /translation="MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYA
                     KFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDA
                     GSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
                     EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLN
                     VFTLNIATYIFRHREETRVFLTMQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGS
                     AAHQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTT
                     KHS"
     gene            complement(19232..20482)
                     /locus_tag="RFE25_000207"
     CDS             complement(19232..20482)
                     /locus_tag="RFE25_000207"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDU2815313.1"
                     /translation="MLNAQQFLNQFSLEAPLDESLYPIIRDICQEVKVHGDKALKMYN
                     LTFDHTKTDHLEISHEQIKAAFDTLDEKTKQALQQSYERIKAYQESIKQTNQQLEESV
                     ECYEIYHPLESVGIYVPGGKASYPSTVLMTATLAQVAGVENIVVVTPPQPNGVSQEVL
                     AACYITQVNQVFQVGGAQSIAALTYGTETIPKVDKIVGPGNQFVAYAKKYLFGQVGID
                     QIAGPTEIALIIDDTADLDAIVYDVFAQAEHDELARTYVIGEDAQVLKDLESRIAKAL
                     PNVDRYDIVSKSIANQHYLIHASNFDEACHVMNTIAPEHASIQTVNPQPYIEKVKYVG
                     ALFIGHYSPEVIGDYVAGPSHVLPTNRTARFTNGLSVNDFLTRNTVIHLSKDTFEQIA
                     DSAQHIAHVEALYNHQQSILIRQS"
     gene            complement(20475..21089)
                     /locus_tag="RFE25_000208"
     CDS             complement(20475..21089)
                     /locus_tag="RFE25_000208"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDU2815314.1"
                     /translation="MLRIAIAKGRLMDSLINYLDVIEYTTLSETLKNRERQLLLSVDN
                     IECILVKGSDVPIYVEQGMADIGIVGSDILDERQYNVNNLLNMPFGACHFAVAAKPET
                     TNYRKIATSYVHTAETYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLKA
                     NGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA"
     gene            complement(21107..21925)
                     /locus_tag="RFE25_000209"
     CDS             complement(21107..21925)
                     /locus_tag="RFE25_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDU2815315.1"
                     /translation="MNNSEQLIALKESETAFLKYFNKADYELVDFSVVEKLDWKQLNH
                     EDLQQMGERNFWQHEHQIYALRNDFTDQLLRYYSMYPTAATKVAYTGLIIRNNEAAVQ
                     VGLENYAPSLANVQQSLKLFIQFIQQQLRDNVHFVVLGHYQLLDALLDKSLQTPDILS
                     MIEERNLSGLVTYLSTEHPIVQILKENTQQQLNVLEHYIPNDHPALVELKIWERWLHT
                     QGYKDIHLDITAQPPRSYYTGLFIQCHFAENESRVLTGGYYKGSIEGFGLGLTL"
     gene            complement(22229..23353)
                     /locus_tag="RFE25_000210"
     CDS             complement(22229..23353)
                     /locus_tag="RFE25_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDU2815316.1"
                     /translation="MHKKYLLLFFLLLSVALLYSCSKQNEKAQNKSVNPNEYAKHKSK
                     MDEHWETYHGQVYHVFYHPLITDPKVAFTGDTHQAKGNNDWMITVSEFKKSLNELYKN
                     NYIIVNPHDVYDLSSHHVKAKKIKLPKGKKPLIISIDDMNYYSYMRHHGYADRLVLDK
                     NKHVVSETTDKKGHATYSDDNDIVPILNKFVKEHPDFSLNGEKGVVALTGYEGVLGYR
                     TNELTSKDYTKNKKAAEEVVRAMKRDGWSFASHSYGHINFEKTSLEGIKRDTKRWKDE
                     VEPIVGKTDMFVFPHGAQDRHTQAYDYLVDEAEFKFIAGVGPNNFTDISATNVYQDRV
                     AIDGLNLFEFKYKLKPFFNPENVYSKQDRQFFKGNRDYEE"
     gene            complement(23471..23968)
                     /locus_tag="RFE25_000211"
     CDS             complement(23471..23968)
                     /locus_tag="RFE25_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2815317.1"
                     /translation="MINTERLNLMIPSSSHLIELYNICSHPQANIYTPKGLHNSKLDT
                     QRWIEKWQNHWQQYQFGYFVLVKKIDCSVIGICGYEYRQLKQETVLNLFYKLHPSFEG
                     QGYACEAITAITNFVNYIDQETVKVIRTNKCNQRSINLAERLKFKRDKAMDDIINQGD
                     IVFYK"
     gene            complement(24015..24848)
                     /locus_tag="RFE25_000212"
     CDS             complement(24015..24848)
                     /locus_tag="RFE25_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDU2815318.1"
                     /translation="MNQYNTIGFHPGNSRIHQLNATVKLLFLLVVSISAMVTYDTRYL
                     ILISASSILLFKYAHIEWKQVRFVVKFILFFTILNIIAVYIFDPEYGVKIYNQRTELV
                     NGIGRFTLTSQELFYLFNLILKYISTVPLALIFLFTTNPSHFAASLNQLGVNYKISYA
                     VSLALRYIPDIQETYFNISQAQQARGYDNSKKAKFTSRVKGIKRIVLPLIFSSIERID
                     TISTAMELRQFGQYKRRTWYVKKQLKKDDYVVLCLTLILLMLVVTLFFLNNSRYFNPW
                     H"
     gene            complement(24845..26548)
                     /locus_tag="RFE25_000213"
     CDS             complement(24845..26548)
                     /locus_tag="RFE25_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815319.1"
                     /translation="MTEPIISFKDFSFQYHSQATPTLQNINVDIYPGEKVLVVGASGS
                     GKSTFANCINGLIPFKTKGNITGELYINNQDATVSCLHDRSNVVGTVLQDTDGQFIGL
                     TAAEDMAFLLENNCVEQDDMKKNVSYWAEKVGMIEHLNHRPQDLSGGQKQRVSLGGIL
                     IHRTPILILDEPLANLDPATGHETLRLLNNIHEETKSTMIIVEHRLEESLDDTFDRVL
                     LFKDGKIIANTTPSDLLKSSKLKEAGIREPLYCTALKYAEVDVESIDNLANLRDVCMS
                     EHVKFKVKKWIDETSANNDNKYKSEPLLELNEVCVQYSDYSNSVLNNVQLNVYRREML
                     SIVGHNGAGKSTLAKAICGFLDITGNIQFCNRGFNQLSISERSEFVGYVMQNPNHMIS
                     EKMIYDEVALGLRARGMKESDIKIRVENVLKICGLYAFRNWPIAALSYGQKKRVTIAS
                     VLVLNPEIIILDEPTAVYHYNEIMSFLIELNRQGKTIIMITHDMHLLSEYSSRTVVLS
                     KGQVVADTTPVLILNDKKICEIASLRQTSLFEMAEYIGISEPQKLVQLFINHDRKVRR
                     Q"
     gene            complement(26601..27155)
                     /locus_tag="RFE25_000214"
     CDS             complement(26601..27155)
                     /locus_tag="RFE25_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HDU2815320.1"
                     /translation="MKKQDISVKTVVAIGIGAAVFVILGRFVVIPTGFPNTNIETSYA
                     FLALISAIFGPFAGLMTGLVGHAIKDFTTYGSAWWSWVICSGIIGCLYGWIGLKLNLS
                     SGLFSRKSMIYFNIGQIIANIICWALIAPTLDILIYNEPANKVYTQGVISAVLNIISV
                     GIIGTILLKAYASSQIKKGSLRKE"
     gene            complement(27184..28032)
                     /locus_tag="RFE25_000215"
     CDS             complement(27184..28032)
                     /locus_tag="RFE25_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HDU2815321.1"
                     /translation="MGNYLVLQSDFGLSDGAVSAMYGVAYTVSDDIRVENLTHDIPPY
                     DIWVASYRLYQTVKYWPKGTVFVSVVDPGVGSDRRSIACLTYSGHYIITPDNGSLSHI
                     KHYEGIKKVIEIDEVKSRLPHSEESHTFHGRDVYAYNGARLAANKIAFERLGQAINVD
                     SIEALEIREATKNEDSVTGSIDILDIRFGSLWTNIPLAFLKSLEIVHGNNLVVTIYHQ
                     DKKVYQNIIKFARSFADVNVGEPLVYVNSLVNIGVAVNQDSFSDLYHIGTGNDWTIHL
                     SKAPSI"
     gene            28411..28926
                     /locus_tag="RFE25_000216"
     CDS             28411..28926
                     /locus_tag="RFE25_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenoid-binding protein"
                     /protein_id="HDU2815322.1"
                     /translation="MTNFTFDGAHSSLEFQIKHLMVSKVKGSFDQFDVAVEGDINDFS
                     TLKATATIIPSSINTKNEARDNHLKSGDFFGTDEFDKITFETKSVTENKVVGDLTIKG
                     ITNEETFDVEFNGVSKNPMDGSQVTGVIVTGTINRENYGINFNQALETGGVMLGKDVK
                     FEASAEFSISE"
     gene            complement(29077..30048)
                     /locus_tag="RFE25_000217"
     CDS             complement(29077..30048)
                     /locus_tag="RFE25_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="HDU2815323.1"
                     /translation="MSQQDLPTLFYSGKSNSAVPIISESELQTITAEPWLEISKKGLQ
                     LEGLNFDRQGQLFLLDVFEGNIFKINPETKEIKRPFVSHKANPAAIKIHKDGRLFVCY
                     LGDFKSTGGIFAATENGDNLQDIIEDLSTAYCIDDMVFDSKGGFYFTDFRGYSTNPLG
                     GVYYVSPDFRTVTPIIQNISVANGIALSTDEKVLWVTETTANRLHRIALEDDGVTIQP
                     FGATIPYYFTGHEGPDSCCIDSDDNLYVAMYGQGRVLVFNKRGYPIGQILIPGRDEGH
                     MLRSTHPQFIPGTNQLIICSNDIEMGGGSMLYTVNGFAKGHQSFQFQ"
     gene            30292..31248
                     /locus_tag="RFE25_000218"
     CDS             30292..31248
                     /locus_tag="RFE25_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDU2815324.1"
                     /translation="MNYQVLLYYKYTTIDDPEQFAQDHLAFCKAHHLKGRILVSTEGI
                     NGTLSGTKEETEQYMAHMHADERFKDMVFKIDEAEGHAFKKMHVRPRKEIVALDLEDD
                     VDPRHTTGQYLSPVEFRKALEDDDTVIIDARNDYEFDLGHFRGAIRPDITRFRDLPDW
                     IKENKALFTDKKVVTYCTGGIRCEKFSGWLLKEGFEDVAQLHGGIATYGKDPETKGQY
                     WDGKMYVFDDRISVDINQVEKTIIGKDWFDGKPCERYINCANPECNKQILVSEENETK
                     YLGACSYECAKHERNRYVQANNISDNEWQQRLTNFDDLHQHA"
     gene            31400..32038
                     /gene="pcp"
                     /locus_tag="RFE25_000219"
     CDS             31400..32038
                     /gene="pcp"
                     /locus_tag="RFE25_000219"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDU2815325.1"
                     /translation="MHILVTGFAPFDNQNINPSWEAVTQLEDIIGTHTIDKLKLPTSF
                     KKVDNIINKTLASNHYDVVLAIGQAGGRNAITPERVAINIDDARIPDNDDFQPIDQAI
                     HLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTYVCNHVLYHLGYLQDKHYPHLR
                     FGFIHVPYIPEQVIGKPDTPSMPLEKIVAGLTAAIEAISNDEDLRIALGTTE"
     gene            complement(32157..32924)
                     /locus_tag="RFE25_000220"
     CDS             complement(32157..32924)
                     /locus_tag="RFE25_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815326.1"
                     /translation="MLTKQSQDFLEKLRVELLFRGKTEAEVEELLEELEDHLTMAEKN
                     NEDTSSIINTPIKSMADQLSPEISLTTGLYKYITLYFSFILAVIIIPRFLDLGTFDVT
                     IAFLLYIASIVILGVVIGMLILRNTLVRFGDQKITYVINVTYGIVVFLWMIFGGLIIK
                     KYPIYSFFELSDKQSFIVGLVLLIALIVICILIKQKIYALIVLVISLPSLIARIAAIF
                     SKEPDTFNLVSVSILIILNIAFIIYTFVNFRKLKKED"
     gene            complement(32914..33252)
                     /locus_tag="RFE25_000221"
     CDS             complement(32914..33252)
                     /locus_tag="RFE25_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDU2815327.1"
                     /translation="MSVSDQIMKGLLDGAILGLIAQGETYGYEIMTKLKNQEFPEISE
                     GSIYPVLMRLNKKGYVDTTIKKSSNGGPRRKYYTITDSGLKELKVFKSKWQALNKGMI
                     NLFGGENDVN"
     gene            33419..33883
                     /gene="bstA"
                     /locus_tag="RFE25_000222"
     CDS             33419..33883
                     /gene="bstA"
                     /locus_tag="RFE25_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol transferase BstA"
                     /protein_id="HDU2815328.1"
                     /translation="MTTKTVFDVIDMGLGYLVNVYDAWKVEKVLDDYHEPFSNTIHWQ
                     FGHVLTIFESALAVAGKENIDLNIYRPLFGNGSSPDEWKDEVPSIEKILEGLQTLPER
                     ARNLTEDDLAIELKQPIVGCNNLEELLVLNAIHIPLHAGKIEEMSRILKNLK"
     gene            34121..35539
                     /locus_tag="RFE25_000223"
     CDS             34121..35539
                     /locus_tag="RFE25_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HDU2815329.1"
                     /translation="MENTVKYRKFILPIVVGLLIWALTPFKPDAVDPTVWYMFAIFVA
                     TIIACITQPMPIGAVSIIGFTIMVLVGIVDMKTAVAGFGNNSIWLIAMAFFISRGFVK
                     TGLGRRIALHFVKLFGKKTLGLAYSIVGVDLILAPATPSNTARAGGIMFPIIKSLSES
                     FGSKPKDGSARKMGAFLVFTEFQGNLITAAMFLTAMAGNPLAQNLASSTSNVHITWMN
                     WFLAALVPGLVSLIVVPFIIYKIYPPTVKETPNAKSWAENELATMGKIALAEKFMIGI
                     FVIALTLWIVGSFIHIDATLTAFIALALLLLTGVLTWQDILNETGAWNTLVWFSVLVL
                     MADQLNKLGFIPWLSKSIATSLGGLSWPIVLVILILFYFYSHYLFASSTAHISAMYAA
                     LLGVAIAAGAPPLFSALMLGFFGNLLASTTHYSSGPAPILFSSGYVTQKRWWTMNLIL
                     GFVYFIIWIGLGSLWMKVIGIF"
     gene            complement(35953..36861)
                     /gene="rarD"
                     /locus_tag="RFE25_000224"
     CDS             complement(35953..36861)
                     /gene="rarD"
                     /locus_tag="RFE25_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HDU2815330.1"
                     /translation="MNIEYKKGIFLALSAYILWGILPIYWQFVDAIGAFEILAFRIIF
                     SAIFMIFILAVGQKQRNAFQRDMNQLLGKPIQLLAIVVAGYVITLNWGTFIWAVTNGH
                     VLQTSLGYYINPLVSILLALIFLKERFNKFEWLAILFAFIGVLYMTLKIGEFPIVSII
                     LALSFGTYGLLKKVVHIDAISSITIECIVTAPAGLIYVIYLWQQHQMSFGLNMSSFWL
                     LFSGAITAIPLILFSAGAKRIPLSLIGFIQYVGPTIMFVLGIFVFKEPFSIDQLITFI
                     FIWTGIVLYSLSQYIKLKKHPVAKTL"
     gene            37083..37658
                     /locus_tag="RFE25_000225"
     CDS             37083..37658
                     /locus_tag="RFE25_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDU2815331.1"
                     /translation="MTLPKIGKPATRALNSQGIYTLEAVSQYTKSSLMEMHGVGPKAI
                     SILEQALFQHQLHFKTEVQSSLPFKLTGDVSCNHAPKRQQMIDFIVATAALDIELLRS
                     LVTTEFIWSVPGHFDIYGPQILIQELSNYYNQVASLNIHSNITHGCLGSMHGIEILKT
                     GKEIHFAHFFEFENHKKDAKLSKVTSYIVVA"
     gene            37820..38836
                     /locus_tag="RFE25_000226"
     CDS             37820..38836
                     /locus_tag="RFE25_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HoxN/HupN/NixA family nickel/cobalt transporter"
                     /protein_id="HDU2815332.1"
                     /translation="MTVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGI
                     LAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGVGFYFSIGHSSVVFLMAVFLGIS
                     VKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEV
                     DVLLESRGFVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAI
                     SFIGILSLPILFASGMSLLDTLDGVVMKYAYNWAFFNPIRKIYYNITITAISVMAALV
                     IGMIELLQILADKLDLHGAFWAFIGSIEFDYLGYILVALFLITWLISSLIWKFGRIEH
                     KWSK"
     gene            39079..39873
                     /locus_tag="RFE25_000227"
     CDS             39079..39873
                     /locus_tag="RFE25_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylamine N-acetyltransferase"
                     /protein_id="HDU2815333.1"
                     /translation="MNIAKLENYLQIDSSRYNRPSIEALNYYATRFMLTVPFENIDVQ
                     NSKPISINIDALFNKIVHDKRGGFCYELNTFFKAYLQQKGFNPELMSATIHTPGGGRS
                     LNGSHASLVVSINDVFYVTDVGFGDLPLHAIPITSSEHTQPITDISGTFRAIFNNEDK
                     DIFYVQKFENDHWHTKYEAEFKPKQIEDFNSNIEYNQTHPDSIFVQHLLITMPQSFGR
                     ATMSENHLTLTRNGSSEKFDVTKDNYKHFLEKYFGLNVTINRIEKQ"
     gene            complement(40007..40519)
                     /locus_tag="RFE25_000228"
     CDS             complement(40007..40519)
                     /locus_tag="RFE25_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HDU2815334.1"
                     /translation="MEKGNQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLF
                     VLINGVIQIIYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFW
                     FIFSSIAGLFTFTGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFVFV
                     GVIYVVDALA"
     gene            40802..41560
                     /gene="vraD"
                     /locus_tag="RFE25_000229"
     CDS             40802..41560
                     /gene="vraD"
                     /locus_tag="RFE25_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide resistance ABC transporter ATP-binding
                     subunit VraD"
                     /protein_id="HDU2815335.1"
                     /translation="MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSG
                     KTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFRKESLGFIFQDYSILPTLTVK
                     ENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHK
                     PQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDG
                     QIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI"
     gene            41550..43430
                     /gene="vraE"
                     /locus_tag="RFE25_000230"
     CDS             41550..43430
                     /gene="vraE"
                     /locus_tag="RFE25_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide resistance ABC transporter permease
                     subunit VraE"
                     /protein_id="HDU2815336.1"
                     /translation="MTFNHIVFKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGV
                     NNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILK
                     MLALEQMIVFLITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTIFML
                     IIAYVLILFQSALFLKRRSILSMMKDSIKTDATTAKVTTAEVISGVLGIAMIALGYYM
                     ATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVV
                     FTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNEFNVVATQ
                     DAKQFETKLSQQQITFSKNAYETITVDNVKDQVITLENGSDSGRTNSILSANNKVTGN
                     NAIITNTKSLPNIINIHLNKDLVVKGTKNETFRVTQEDKGRVYPLNLSFNSPVVEVSP
                     EKYQQLKTQNNVHTFYGYDIKQTSQKEKAQAIAKQFGDKVITYDEMKKEVDATNGILI
                     FVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNF
                     GLPLLIAILHAVFAAIAFMKLMGNISFMPVIVVIVVYTLIYITFALIAFVHSNKLIKK
                     TI"
     gene            43522..43713
                     /gene="vraH"
                     /locus_tag="RFE25_000231"
     CDS             43522..43713
                     /gene="vraH"
                     /locus_tag="RFE25_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide resistance ABC transporter activity
                     modulator VraH"
                     /protein_id="HDU2815337.1"
                     /translation="MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSVVTTPIIGI
                     PAGLLGGAYYLKRREEKGK"
     gene            44105..44305
                     /locus_tag="RFE25_000232"
     CDS             44105..44305
                     /locus_tag="RFE25_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDU2815338.1"
                     /translation="MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEG
                     QKVTFEITEGQRGDQAVNVQTV"
     gene            complement(44423..44992)
                     /locus_tag="RFE25_000233"
     CDS             complement(44423..44992)
                     /locus_tag="RFE25_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2815339.1"
                     /translation="MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDI
                     HNLLMMCELFNVTLDDLVKGTIPFVPDIKVQRSLNLWTYVMLIFMTLAAILMGPLVVY
                     WNWTWGITVAIILGIGFYASMKIEDLKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNT
                     MTNALSIISAIGILSLIIFLSVYMANKFL"
     gene            complement(45252..45647)
                     /locus_tag="RFE25_000234"
     CDS             complement(45252..45647)
                     /locus_tag="RFE25_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3147 family protein"
                     /protein_id="HDU2815340.1"
                     /translation="MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVS
                     MFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFIS
                     AVCIFEAVEFIAQKRLEKHSWKAGKSNSK"
     gene            complement(45715..46068)
                     /locus_tag="RFE25_000235"
     CDS             complement(45715..46068)
                     /locus_tag="RFE25_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3147 family protein"
                     /protein_id="HDU2815341.1"
                     /translation="MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFL
                     AAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYIKHKGYRKGAIFTVV
                     CWFVISLAIFSIRHL"
     gene            complement(46519..47358)
                     /gene="noc"
                     /locus_tag="RFE25_000236"
     CDS             complement(46519..47358)
                     /gene="noc"
                     /locus_tag="RFE25_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDU2815342.1"
                     /translation="MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQP
                     RQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVI
                     IRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIA
                     NKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRV
                     RQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRI
                     YKR"
     gene            complement(47401..48120)
                     /gene="rsmG"
                     /locus_tag="RFE25_000237"
     CDS             complement(47401..48120)
                     /gene="rsmG"
                     /locus_tag="RFE25_000237"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDU2815343.1"
                     /translation="MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSI
                     TDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSL
                     NKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLP
                     LIKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFKLPEDAGERQMFIIDKKR
                     QTPKKYPRKPGTPNKTPLLEK"
     gene            complement(48120..49997)
                     /gene="mnmG"
                     /locus_tag="RFE25_000238"
     CDS             complement(48120..49997)
                     /gene="mnmG"
                     /locus_tag="RFE25_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501497.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDU2815344.1"
                     /translation="MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMP
                     CNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLY
                     QQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGE
                     IILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPG
                     DDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPS
                     IEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMM
                     RAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKV
                     LNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGY
                     ELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAID
                     LLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKI
                     PEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVS
                     D"
     gene            complement(50064..51443)
                     /gene="mnmE"
                     /locus_tag="RFE25_000239"
     CDS             complement(50064..51443)
                     /gene="mnmE"
                     /locus_tag="RFE25_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDU2815345.1"
                     /translation="MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLND
                     VPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELT
                     MTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLI
                     KKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEFNRLLDTGAQGKIM
                     REGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDT
                     AGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIV
                     NKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYV
                     SNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQ
                     LFSQFCLGK"
     gene            complement(51600..51953)
                     /gene="rnpA"
                     /locus_tag="RFE25_000240"
     CDS             complement(51600..51953)
                     /gene="rnpA"
                     /locus_tag="RFE25_000240"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDU2815346.1"
                     /translation="MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFR
                     LGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSL
                     EHVLKIAKVFNKKIK"
     gene            complement(52074..52211)
                     /gene="rpmH"
                     /locus_tag="RFE25_000241"
     CDS             complement(52074..52211)
                     /gene="rpmH"
                     /locus_tag="RFE25_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDU2815347.1"
                     /translation="MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLS
                     A"
     gene            52942..54303
                     /gene="dnaA"
                     /locus_tag="RFE25_000242"
     CDS             52942..54303
                     /gene="dnaA"
                     /locus_tag="RFE25_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDU2815348.1"
                     /translation="MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLS
                     SIPFNANWLNQQYAEIIQAILFDVVDYEVKPHFITTEELANYSNNETATPKETTKPST
                     ETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGL
                     GKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLI
                     DDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIV
                     DITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLL
                     GKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPR
                     QIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEI
                     RNV"
     gene            54581..55714
                     /gene="dnaN"
                     /locus_tag="RFE25_000243"
     CDS             54581..55714
                     /gene="dnaN"
                     /locus_tag="RFE25_000243"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDU2815349.1"
                     /translation="MMEFTIKRDYFITQLNDTLKAISPRTTLPILTGIKIDAKEHEVI
                     LTGSDSEISIEITIPKTVDGEDIVNISETGSVVLPGRFFVDIIKKLPGKDVKLSTNEQ
                     FQTLITSGHSEFNLSGLDPDQYPLLPQVSRDDAIQLSVKVLKNVIAQTNFAVSTSETR
                     PVLTGVNWLIQENELICTATDSHRLAVRKLQLEDVSENKNVIIPGKALAELNKIMSDN
                     EEDIDIFFASNQVLFKVGNVNFISRLLEGHYPDTTRLFPENYEIKLSIDNGEFYHAID
                     RASLLAREGGNNVIKLSTGDDVVELSSTSPEIGTVKEEVDANDVEGGSLKISFNSKYM
                     MDALKAIDNDEVEVEFFGTMKPFILKPKGDDSVTQLILPIRTY"
     gene            56095..56340
                     /gene="yaaA"
                     /locus_tag="RFE25_000244"
     CDS             56095..56340
                     /gene="yaaA"
                     /locus_tag="RFE25_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDU2815350.1"
                     /translation="MIILVQEVVVEGDINLGQFLKTEGIIESGGQAKWFLQDVEVLIN
                     GVRETRRGKKLEHQDRIDIPELPEDAGSFLIIHQGEQ"
     gene            56337..57449
                     /gene="recF"
                     /locus_tag="RFE25_000245"
     CDS             56337..57449
                     /gene="recF"
                     /locus_tag="RFE25_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDU2815351.1"
                     /translation="MKLNTLQLENYRNYDEVTLKCHPDVNILIGENAQGKTNLLESIY
                     TLALAKSHRTSNDKELIRFNADYAKIEGELSYRHGTMPLTMFITKKGKQVKVNHLEQS
                     RLTQYIGHLNVVLFAPEDLNIVKGSPQIRRRFIDMELGQISAVYLNDLAQYQRILKQK
                     NNYLKQLQLGQKKDLTMLEVLNQQFAEYAMKVTDKRAHFIQELESLAKPIHAGITNDK
                     EALSLNYLPSLKFDYAQNEAARLEEIMSILSDNMQREKERGISLFGPHRDDISFDVNG
                     MDAQTYGSQGQQRTTALSIKLAEIELMNIEVGEYPILLLDDVLSELDDSRQTHLLSTI
                     QHKVQTFVTTTSVDGIDHEIMNNAKLYRINQGEIIK"
     gene            57459..59393
                     /gene="gyrB"
                     /locus_tag="RFE25_000246"
     CDS             57459..59393
                     /gene="gyrB"
                     /locus_tag="RFE25_000246"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDU2815352.1"
                     /translation="MVTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGL
                     HHLVWEIVDNSIDEALAGYANKIEVVIEKDNWIKVTDNGRGIPVDIQEKMGRPAVEVI
                     LTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQF
                     DLKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERD
                     EENVREDSYHYEGGIKSYVELLNENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATN
                     LLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEEKDRLSGEDTREGMTAII
                     SIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARA
                     RVAAKKAREVTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSR
                     TQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTD
                     ADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRELDKLK
                     SELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGD
                     VVENRRQFIEDNAVYANLDF"
     gene            59430..62099
                     /gene="gyrA"
                     /locus_tag="RFE25_000247"
     CDS             59430..62099
                     /gene="gyrA"
                     /locus_tag="RFE25_000247"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDU2815353.1"
                     /translation="MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKP
                     VHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDLSIYEAMVRMAQDFSYRYP
                     LVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL
                     PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDF
                     PTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEK
                     IAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVN
                     MIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHID
                     EIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLN
                     YISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLGGFEDLEDEDLIPEEQIV
                     ITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGR
                     VYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVV
                     KRSALSNFSRINRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRP
                     LGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTENGYGKRTPVNDYRLSNRGGK
                     GIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRL
                     GDDQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVID
                     SEENDEDGRIEVRQDFMDRVEEDIQQSSDEDEE"
     gene            complement(62187..62999)
                     /locus_tag="RFE25_000248"
     CDS             complement(62187..62999)
                     /locus_tag="RFE25_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HDU2815354.1"
                     /translation="METLNSINIPKRKEDSHKGDYGKILLIGGSANLGGAIMLAARAC
                     VFSGSGLITVATHPTNHSALHSRCPEAMVIDINDTKMLTKMIEMTDSILIGPGLGVDF
                     KGNNAITFLLQNIQPHQNLIVDGDAITIFSKLKPQLPTCRVIFTPHLKEWERLSGIPI
                     EEQTYERNREAVDRLGATVVLKKHGTEIFFKDEDFKLTIGSPAMATGGMGDTLAGMIT
                     SFVGQFDNLKEAVMSATYTHSFIGENLAKDMYVVPPSRLINEIPYAMKQLES"
     gene            63325..64839
                     /gene="hutH"
                     /locus_tag="RFE25_000249"
     CDS             63325..64839
                     /gene="hutH"
                     /locus_tag="RFE25_000249"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HDU2815355.1"
                     /translation="MTLYLDGETLTIEDIKSFLQQQSKIEIIDDALERVKKSRAVVER
                     IIENEETVYGITTGFGLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMIL
                     RLNTLLKGHSGATLELVRQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEG
                     KVLYRGEEKDSDDVLRELNRQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQS
                     EWIAALTHQSLNGIIDAYRHDVHSVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQD
                     AYTLRCIPQIHGASFQVFNYVKQQLEFEMNAANDNPLIFEEANETFVISGGNFHGQPI
                     AFALDHLKLGVSELANVSERRLERLVNPQLNGDLPAFLSPEPGLQSGAMIMQYAAASL
                     VSENKTLAHPASVDSITSSANQEDHVSMGTTAARHGYQIIENARRVLAIECVIALQAA
                     ELKGVEGLSPKTRRKYEEFRSIVPSITHDRQFHKDIEAVAQYLKQSIYQTTACH"
     misc_binding    64912..65128
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            65218..66504
                     /gene="serS"
                     /locus_tag="RFE25_000250"
     CDS             65218..66504
                     /gene="serS"
                     /locus_tag="RFE25_000250"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDU2815356.1"
                     /translation="MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISA
                     TEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILC
                     RIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSG
                     ARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDL
                     FKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLI
                     RLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKT
                     YDIEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRT
                     FAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK"
     gene            67155..67850
                     /locus_tag="RFE25_000251"
     CDS             67155..67850
                     /locus_tag="RFE25_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDU2815357.1"
                     /translation="MATHLSFRQGVQECIPTLLGYAGVGISFGIVASSQNFSILEIIL
                     LCLVIYAGAAQFIMCALFIAGTPISAIVLTVFIVNSRMFLLSMSLAPNFKTYGFWNRV
                     GLGSLVTDETFGVAITPYLKGEAINDRWMHGLNITAYLFWAISCVAGALFGEYISNPQ
                     TLGLDFAITAMFIFLAIAQFESITKSRLRIYIVLIIAVIVMMLSLSMFMPSYLAILIA
                     ATISAALGVMMER"
     gene            67847..68176
                     /locus_tag="RFE25_000252"
     CDS             67847..68176
                     /locus_tag="RFE25_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDU2815358.1"
                     /translation="MITHMNMLILILLCGIVTLLIRIIPFIMISKVQLPDVVVRWLSF
                     IPITLFTALVIDSIIQQTPHGEGYTLNIPYIIALIPTVILSIITRSLTITIISGIVIM
                     ATLRFFF"
     regulatory      68381..68479
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            68539..69507
                     /locus_tag="RFE25_000253"
     CDS             68539..69507
                     /locus_tag="RFE25_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDU2815359.1"
                     /translation="MTNYTVDTLNLGKFITESGEVIDNLRLRYEHVGYHGQPLVVVCH
                     ALTGNHLTYGTDDYPGWWREIIDGGYIPIHDYQFLTFDVIGSPFGSSSPLNDPHFPKK
                     LTLRDIVRANERGIQALGYDKINILIGGSLGGMQAMELLYNQQFEVDKAIILAATSRT
                     SSYSRAFNEIARQAIHLGGKEGLSIARQLGFLTYRSSKSYDERFTPDEVVAYQQHQGN
                     KFKEHFDLNCYLTLLDVLDSHNIDRGRTDVTHIFKNLETKVLTMGFIDDLLYPDDQVR
                     ALGERFKYHRHFFVPDNVGHDGFLLNFSTWAPNLYHFLNLKHFKRK"
     gene            69800..70738
                     /locus_tag="RFE25_000254"
     CDS             69800..70738
                     /locus_tag="RFE25_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDU2815360.1"
                     /translation="MGVAYVFSKIQPKATIIATITLVFVALALYLVPGLGLIFALFAT
                     IPGIVLWNKSIQSFGVSALITVIITTVLGNTFVLSAIILVLIASLIIGQLLKERTSKE
                     RMLYVTTVAMSLISLIAFMLLQTFGRIPPSASIVKPFKQTLHEAITMSGADANMTQIL
                     EEGFRQATVQLPGFIIIITFLIVLINLIVTFPVLRKFKIATPVFKPLFAWQMSGILLW
                     IYIIVIICLLFTGQPSVFQSILLNFQLVLSLVMYIQGLSVIHFFGKAKGLPNAVTILL
                     LIIGTILTPTTHIVGLLGVIDLSLNLKRIMKNNSKK"
     gene            70753..72720
                     /gene="gdpP"
                     /locus_tag="RFE25_000255"
     CDS             70753..72720
                     /gene="gdpP"
                     /locus_tag="RFE25_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP phosphodiesterase GdpP"
                     /protein_id="HDU2815361.1"
                     /translation="MNRQSTKKALLIPFVIMIITAIVLMGVWFIFNSLIALIASIVLV
                     VMIIVSIILFRQALMKMDSYVDGLSAQISTTNNKAIKHLPIGIIVLDENDHIEWVNQF
                     MTNHMEANVISESVNEVFPNILKQLDRVKSVEIEYNQYHFQVRYSENDHCLYFFDITE
                     QVQTNELYENSKPIIATLFLDNYDEITQNMNDTQRSEINSMVTRVISRWATEYNIFFK
                     RYSSDQFVAYLNQKILADLEESKFDILSQLREKSVGYRAQLTLSIGVGEGTENLIDLG
                     ELSQSGLDLALGRGGDQVAIKSINGNVRFYGGKTDPMEKRTRVRARVISHALKDILAE
                     GDKVIIMGHKRPDLDAIGAAIGVSRFAMMNNLEAYIVLNETDIDPTLRRVMNEIDKKS
                     ELRERFITSDDAWDMMTSKTTVVIVDTHKPELVLDENVLNKANRKVVIDHHRRGESFI
                     SNPLLIYMEPYASSTAELVTELLEYQPTEQRLTRLESTVMYAGIIVDTRNFTLRTGSR
                     TFDAASYLRAHGADTILTQHFLKDDVDTYINRSELIRTVKVEDNGIAIAHGSDDKIYH
                     PVTVAQAADELLSLEGIEASYVVARREDNLIGISARSLGSVNVQLTMEALGGGGHLTN
                     AATQLKGVTVEEAIAQLQQAITEQLSRSEDA"
     gene            72717..73163
                     /gene="rplI"
                     /locus_tag="RFE25_000256"
     CDS             72717..73163
                     /gene="rplI"
                     /locus_tag="RFE25_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDU2815362.1"
                     /translation="MKVIFTQDVKGKGKKGEVKEVPVGYANNFLLKKNYAVEATPGNL
                     KQLELQKKRAKQERQQEIEDAKALKETLSNIEVEVSAKTGEGGKLFGSVSTKQIAEAL
                     KAQHDIKIDKRKMDLPNGIHSLGYTNVPVKLDKEVEGTIRVHTVEQ"
     gene            73195..74595
                     /gene="dnaB"
                     /locus_tag="RFE25_000257"
     CDS             73195..74595
                     /gene="dnaB"
                     /locus_tag="RFE25_000257"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDU2815363.1"
                     /translation="MDRMYEQNQMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFY
                     RGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSTEGTLNEAGGPQYLAELSTNVPTTRNV
                     QYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFK
                     DIRDVLGQVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTA
                     FALNIAQKVATHEDMYTVGIFSLEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSR
                     FTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGSGSRAS
                     DNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDA
                     DIVAFLYRDDYYNRGGDEDDDDDGGFEPQTNDENGEIEIIIAKQRNGPTGTVKLHFMK
                     QYNKFTDIDYAHADMM"
     gene            74873..76156
                     /locus_tag="RFE25_000258"
     CDS             74873..76156
                     /locus_tag="RFE25_000258"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDU2815364.1"
                     /translation="MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQ
                     FGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELDGLNERGIPTSNLRISNRA
                     QVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLL
                     KSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVL
                     FEGAQGVMLDIDHGTYPFVTSSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGP
                     FPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVL
                     TGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPEN
                     ARKYLERISELCNVQISIFSVGPDREQTNLLKELW"
     gene            76585..76659
                     /locus_tag="RFE25_000259"
     tRNA            76585..76659
                     /locus_tag="RFE25_000259"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:76618..76620,aa:Glu,seq:ttc)
     gene            76667..76739
                     /locus_tag="RFE25_000260"
     tRNA            76667..76739
                     /locus_tag="RFE25_000260"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:76700..76702,aa:Asp,seq:gtc)
     gene            77359..78060
                     /locus_tag="RFE25_000261"
     CDS             77359..78060
                     /locus_tag="RFE25_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2815365.1"
                     /translation="MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYE
                     EEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTK
                     PFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTH
                     REFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEY
                     IVTRRGVGYFLQQHE"
     gene            78073..79899
                     /gene="walK"
                     /locus_tag="RFE25_000262"
     CDS             78073..79899
                     /gene="walK"
                     /locus_tag="RFE25_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HDU2815366.1"
                     /translation="MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDN
                     FKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIII
                     ATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKV
                     IGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTV
                     EMSRGNYTQRVKIYDNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGI
                     IATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDL
                     NEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLT
                     SMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEI
                     IDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRG
                     DKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGL
                     AISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE"
     gene            79892..81226
                     /locus_tag="RFE25_000263"
     CDS             79892..81226
                     /locus_tag="RFE25_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001060131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815367.1"
                     /translation="MNNKEHIKSVILALLVLMSVVLTYMVWNFSPDIANVDNTDSKKS
                     ETKPLTTPMTAKMDTTITPFQIIHSKNDHPEGTIATVSNVNKLTKPLKNKEVKSVEHV
                     RRDHNLMIPDLSSDFTLFDFTYDLPLSTYLGQVLNMNAKVPNHFNFNRLVIDHDADDN
                     IVLYAISKDRHDYVKLTTTTKNDHFLDALAAVKKDMQPYTDIITNKDTIDRTTHVFAP
                     SKPEKLKTYRMVFNTISVEKMNAILFDDSTIVRSSKSGVTTYNNNTGVANYNDKNEKY
                     HYKNLSEDEASSSKMEETIPGTFDFINGHGGFLNEDFRLFSTNNQSGELTYQRFLNGY
                     PTFNKEGSNQIQVTWGEKGVFDYRRSLLRTDVVLNSEDNKTLPKLESVRSSLANNSDI
                     NFEKVTNIAIGYEMQDNSDHNHIEVQINSELVPRWYVEYDGEWYVYNDGRLE"
     gene            81227..82015
                     /locus_tag="RFE25_000264"
     CDS             81227..82015
                     /locus_tag="RFE25_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HDU2815368.1"
                     /translation="MNWKLTKTLFIFVFILVNIVLVSIYVNKVNRSHINEVESNNEVN
                     FQQEEIKVPASILNKSVKGIKLEQITGRSKDFSSKAKGDSDLTTSDGGKLLNANISQS
                     VKVSDNNLKDLKDYVNKRVFKGSEYQLSEINSGSVKYEQTYDNFPILNNSKAMLNFNI
                     EDNKAASYKQSMMDDIKPTDGADKKHQVIGVRKAIEALYYNRYLKKGDEVINARLGYY
                     SVVNETNVQLLQPNWEIKVKHDGKDKTNTYYVEATNNNPKIINH"
     gene            82404..83204
                     /locus_tag="RFE25_000265"
     CDS             82404..83204
                     /locus_tag="RFE25_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDU2815369.1"
                     /translation="MSRLIRMSVLASGSTGNATFVENEKGSLLVDVGLTGKKMEELFS
                     QIDRNIQDLNGILVTHEHIDHIKGLGVLARKYQLPIYANEKTWQAIEKKDSRIPMDQK
                     FIFNPYETKSIAGFDVESFNVSHDAIDPQFYIFHNNYKKFTILTDTGYVSDRMKGMIR
                     GSDAFIFESNHDVDMLRMCRYPWKTKQRILGDMGHVSNEDAGHAMTDVITGNTKRIYL
                     SHLSQDNNMKDLARMSVGQVLNEHDIDTEKEVLLCDTDKAIPTPIYTI"
     gene            83431..85749
                     /gene="adsA"
                     /locus_tag="RFE25_000266"
     CDS             83431..85749
                     /gene="adsA"
                     /locus_tag="RFE25_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adenosine synthase AdsA"
                     /protein_id="HDU2815370.1"
                     /translation="MKALLLKTSVWLVLLFSVMGLWQVSNAAEQYTPIKAHVVTTIDK
                     ATTDKQQVTPTKEAAHQFGEEAATNVSASAQGTADEINNKVTSNAFSNKPSTAVSTKV
                     NETHDVDTQQASTQKPTQSATFTLSNAKTASLSPRMFAANVPQTTTHKILHTNDIHGR
                     LAEEKGRVIGMAKLKTIKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDA
                     MAVGNHEFDFGYDQLKKLEGMLDFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVT
                     TPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISHLGIDPSTQETWRGD
                     YLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKVTFNYRNG
                     EVSNIKPSLINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDV
                     RTRETNLGNAIADAMEAYGVKNFSKKTDFAVTNGGGIRASIAKGKVTRYDLISVLPFG
                     NTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYDMNKPSG
                     KRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLA
                     SYLKTANIAKYDTTEPQRMLLGKPAVSEQPAKGQQGSKGSESGKDVQPIGDDKAMNPA
                     KQPATGKVVLLPTHRGTVSSGTEGSGRTLEGATVSSKSGNQLVRMSVPKGSAHEKQLP
                     KTGTNQSSSPAAMFVLVAGIGLIATVRRRKAS"
     gene            86117..86596
                     /gene="rlmH"
                     /locus_tag="RFE25_000267"
     CDS             86117..86596
                     /gene="rlmH"
                     /locus_tag="RFE25_000267"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020363758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDU2815371.1"
                     /translation="MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAP
                     ENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSD
                     FVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK"
     gene            86918..>88172
                     /locus_tag="RFE25_000268"
     CDS             86918..>88172
                     /locus_tag="RFE25_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001569336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3578 domain-containing protein"
                     /protein_id="HDU2815372.1"
                     /translation="MIDNFMQVLKLIKEKRTNNVVKKSDWDKGDLYKTLVHDKLPKQL
                     KVHIKEDKYSVVGKVATGNYSKVPWISIYDENITKETKDGYYLVYLFHPEGEGIYLSL
                     NQGWSKISDMFPRDKNAAKQRALTLSSELNKYITSNEFNTGRFYYAENKDSSYDLKND
                     YPSGYSHGSIRFKYYDLNEGFTEEDMLEDLKKFLELFNELASKVTKTSYDSLVNSIDE
                     IQEDSEIEEIRTAQKDKTLKEVEAPKGIIPKYKKGVSKTTKNDSEIEKSNKENKLTGK
                     VGEKLALNYFNELIDNKIDEDKKEQFRNILNDNPGSQHGHGYDLVAFDPTNTDKAVEK
                     FIEIKTSTSSSIEEPFFMSLNEMFAMKEYKQKYLILRIFNVSGKEPQFYFIDPYANYS
                     EFKDVDDLIDKVFNVEAIQYKVFGEK"
BASE COUNT        29596 a        14839 c        14663 g        29074 t
ORIGIN      
        1 taaacgataa atattatatg caaaatacat ctttaatatt aaagtaatac caatattttt
       61 tcaataaacc tagtgtaata tatgtgtaat tctaaaagat tcttctttaa aaatataaat
      121 accacgacat attgctttaa cattttcatt tataaagcga aaaaatgcat cgctactaag
      181 ttgaatattt agtaacaatg cattgaattc actaaaatga ttaaattact tatctctttt
      241 catctgattg attatcgaaa tttcttcctt ctaaacctgc taactcttct ttagaagctg
      301 caggtgcttt catttcaaat atctcattca ctactgtgta atcgtaatat cctaatctgg
      361 caataggttt aatcgactta atgtccaatt taccattatc aagaataacc ttatcgtcaa
      421 tatgaacttg ggcaactctt cctataacaa tatctacggt agatactggg tctcctgtcg
      481 gaatacgaat cgtttgaacg tactcacatt caaaatgtac tggcgattct ttgactcgat
      541 aacctggtgc ttctatacat gcttctttcg tcacacctgc atattcaaat tcatcctctt
      601 caggtggtag tgccttcgac gataaattaa cagcttctct taaatcatac gtggccatgt
      661 tccatacaaa ccaccctgtc tcttctgcat tttttactgt atctttacgc tcatgatcac
      721 caagaacaga ttgatttgct gcgaacataa ccataggcgg atcccaagtt aagttttgat
      781 actgactata aggcgctaaa ttatctttcc catctttcga tacagtagaa atccaaccta
      841 ttggacgagg tactgtacta cttttaaatg ggtcgtgcgg taaaccatga cttcttacac
      901 cttgttttgg cgaataattc atactatctt caccccttat aagtaattac atttaaggtt
      961 acgccctctt tacataagcg tctaatataa ataaacaatt tatttataag tagaaactat
     1021 atatgacgtg gttgcttata atttgcgttc ttgattcgaa aaattcagat aaggatttat
     1081 acaattaata tttatgatat cttttgtaaa tttaattaat tatagttact tcaatcatga
     1141 ttagtttata ataataaagt gaaattgaaa aagacagcta ttatgcgatg agcgaaaaac
     1201 ttcaagtaaa acaagaattt aacggcgtta caaggcaata cttgaatttc agaacagata
     1261 gtatcgatga tctggataag ttcaaaaaag aattcaaacc tgttatgcac ttaaaaggtg
     1321 atgcattcaa tcaacagtta caatctttga ttaacaaata tccacaaata caaaaaaata
     1381 tgaaatcaga gttcattgct tattatgata aagaaaaaaa tagagaaaca gtaaaaaact
     1441 atgcttggaa ccttcaaaaa tctataaatg acattatgca atcatatcct agcacaaaat
     1501 ttgtacagtt ttataaagat gatgtttccc cgtcaatggt agatggaaat ggccgtttaa
     1561 aatcggatac taatgtaatt tccatcgagg gaggaaagta tgatgagaac aaataatcat
     1621 ataaccgatt tagatgctat tgagttaagt agcggttgga attacaattc gaaattggtg
     1681 actggcaaaa atgcactact atcagatagt cttttaagag atattaaagt attaagttct
     1741 aatgctaaag gcgacgctga catactagaa acagaacttc gtgctgtaat aaacgcaatg
     1801 tctcaaaacg aaggtaaatc tgttgatgca cttaaaaata gtaccacttc tctaaaaaac
     1861 aatctaacca aattaaaaga gcaactcgac aaaactacac attaatttca tacattttga
     1921 gtgaacagaa ttatatttcc atagcaaaca ttcctaaact acacatacgt tacataattg
     1981 attcattttt atagaaacgg gtaaaaatga taaagtaatc atctttcaca aaaatccaaa
     2041 gattgggagg aattaaatat gattttgcgt tacgcaacaa atttaaaact tgcgaaagag
     2101 ctataccaag ccagtaaacc taaattgcaa gaagataagg gtatgattga actgtttgaa
     2161 catacttttg gcttgcaaaa agaacttgta aaatacgtcg gcattgcaga agcaactact
     2221 gctgctttat actcagctag ctttatcaat aaaaacattt ctcgccttgc atcactatca
     2281 acgataggca ttttaagtgt agctgcttac aaacatttcg aagctggcca aggtaaaaaa
     2341 ggtgcacaac atgcattaga tttattaggt cttgctactt taagtttact agatacattt
     2401 tcttgtaata aaaaatagtc ttcattttag aagcacatac tttagcacct gtgtactttt
     2461 gattcaatcc ataaacggta caccgctata gcatgtgttt tattattttt ctggtctctt
     2521 tatcgtaaat attcccccta atttagcata atcatttccg gctaaacgag aaacagcctg
     2581 taatgcgtgt ggattgattt taaaatcacc ctcataaata ctgtcatcaa tatgataagt
     2641 tacaatttca cctattatta aatcagcccc atctaataca tctccaagca atatcatttg
     2701 cgatagttta cattcgaatc tcattttcgc gtctttaatt cctggcgtct taatcgttgt
     2761 agatgttaaa agtgataatc ctgtacgact caactcactg tcaccatatg ctaacggcgc
     2821 tgcagtctca ttaatatctt gaacattatc ttcgtctgta atatgcacaa caaagtctcc
     2881 agtccgttct atattcaagg cagtatcttt tctcttacct cctgcacgtt gaactgcaat
     2941 agcaaccatt ggcggatggt tattaacaat attaaaaaag ctaaatggtg ctgcatttac
     3001 tgatgcatct tgatttaatg ttgtaacaaa tgctataggt cgtggaataa ttgaaccaat
     3061 taataattta tagttttctc tagcagttaa tgattgtgca tcaaacgtat acataatacc
     3121 tacctctttt cttagtatat ctaggtattt ctccgatttt ggttaattta aacatctatt
     3181 ctcctctgaa aatcacttgt atttatttag caaatctttt gaaatatgac acatatgcat
     3241 atcttctgga tatttttcta aatgttgctg atgttcttca gcacttttaa tgtagttaga
     3301 cagcggtaag acttccactg caatttgatc tctgtcttta cgtcgttcaa tgaactgacg
     3361 cgcttcaatt aagtggtcat ctacacaact atataaaccc gttcgatact tttctccaat
     3421 atcatttcct tgttgattca cactgtaagg atcaatgatt tcaaataaat aattcataat
     3481 gtctgtaatt gttaacatac gatcatcgaa atgaagtttg acacattcag cataaccatc
     3541 atacggaccg tctaatttag agcttcttcc atttgctctt cctgcttctg tatgtataat
     3601 tccaggtatt gttgcaaaaa atgcttcaac accccataga caccctcctg ctacataaac
     3661 aactaccata tttacacctc atcatccttt tttatatttt taacaaggtt ataccattta
     3721 ataccgccat gacatgattc tgatacacct tcattacgat acccatattt ttcataaaat
     3781 gaaattaatg attctcgaca tgttaacgtt acaccatgtc gatgatgatt cttagcaaga
     3841 gtttcaaaat agtttagtaa gcgacctgca ataccctgac cttgataatt tggtgctaca
     3901 acaagaccta acacactaat atagccacct tcactattat ttatggagac atttttaaat
     3961 aaatcatcgc taatgtaacg ctcttttatg actggaccgt tgatgtatcc aattacttca
     4021 tcattctttt cagctacaat aaaagtttct tgaatttgtt caattctcaa tttcaatgcc
     4081 tctcgtgttg cagcttcttc cggtgaaaaa ccaatatttt caagtgcaat aatttgatct
     4141 aagtcctgca tgattacttt tcttaatacc ataaaaacac ttccttagcc ctatatatca
     4201 aaagtaatac cttcatcttt atattcatta ttttcaaact accttcacta taaaaaacga
     4261 gtctttttat tgaaagccat tcgccttaat caattagaca agttgtatta tacgaattag
     4321 taaataatca tgattataat tcattttaag catactcaaa aagactggta catgtatacc
     4381 agtctaattc gaaaaaatat atttagttaa aaccatttca aaaacgactt cacttttcct
     4441 ggcttagtcg gtctgtctaa ataaacaaaa ttatcattga ttactgaact ggcatttcga
     4501 agtaatgctt caatatcatt cgaatatttc ttcaatttat gattgtgaaa taattcttgc
     4561 atcaaaaatg gtctttggtc acatgaatgt gcatctgaag ctacaaaatg agccaaatta
     4621 cattctataa attgtaatga taacttttga atgtttttac caaatccacc aactaaagaa
     4681 ctcgatgtta attgactcaa tgccccattt gcaaccaatt catataatat ttctggattt
     4741 ttggcgatac ttctatttct ttcaggatgt gcaatgattg gtatgtagcc tctcgattgt
     4801 atttcaaaaa acaattgttt tgtataatgt ggtacttcgc ccgttggaaa ttcaattaat
     4861 aaatatttcg aacgattaat accttgaata ctaccattat ctaagccttt cagaatcgaa
     4921 tctgtaattc taatttcttg cccgggaaat aatttaatat ccaatgcttg aacttctgga
     4981 tgcgttctta actccgccaa tttcacaagc acttgttgaa atgtattatc atatctcgga
     5041 tgcaaatgat gaggtgtcgc tacaatactt gttacacctt catccttagc ttgctttaat
     5101 agtgcaatac tcttttcaat tgttttagga ccatcatcta tatcaactaa tatatggtta
     5161 tgaatatcaa tcatgattca tcagtcccat aatatgcata gtaactagca cttttatctt
     5221 taggcattct atttaagact acacctaata atttagcacc tgttgcttca ataagttctt
     5281 ttcctttttt aacttcatct ttattattat tttccgaatt aactacgtag acaacattgc
     5341 cggtaaactt tgaaaataat tgcgcatctg taactgtgtt cactggtggc gtatcgataa
     5401 tgacaaagtt ataattcatc aataatgtgt catacaaatt tgcaaatgcc cttgatgtaa
     5461 ttaactctga cggattcggt gggattggcc cagacgtcaa gacgtctaaa tcttgaattt
     5521 cagttgagat aatactgtct tgataagttg accaatttag caataaactt gataggcctt
     5581 cattgtttgg caaattaaaa atataatgct gcgtaggttt acgcatatcc ccgtctacga
     5641 ttagtgtttt ataacctgct tgcgcatatg caactgctaa atttgctgca attgtagact
     5701 tacctgcgcc tggtgcctct gaagtgatta caatgctttg aactgcactg tcaggatttg
     5761 caaacataat atttgatctt atgcctcgaa atttctcgct aataggtgac tttggttgtt
     5821 catggacaat taaacttgat gtacttcttc gtgtattcgt catggtaatt cctcgtaaat
     5881 taaaattttt gtattgaacc taaaataggt aatcctagtt gcgattcaac atcttcttct
     5941 gtcttaatac gcttatctaa taattctttt aagaaaataa tcaatattgc taaaacaata
     6001 ccaacaataa tgctgatcac taagttgaca gatactattg gagatacttt tacagcatta
     6061 tcatgtgctg aggaaagtat cgtaacatta tcaacactca taattttagg catatcatgt
     6121 gcaaaaactt tagatattct attaacaatt ttgtcagatt cagatttatt cccagttgta
     6181 actgatacag taataatctg agagtttgtt tgattggtta cttttaaaaa cgaattcaac
     6241 tcagctgttg aatactgacc atcaaactct ctagatactt tatctagaat tcttggactt
     6301 ttgataattt ccgtatatgt attaacagac tgcaaactac tttgaacatt ttggaaagct
     6361 aaatcacttg aggacttttt catgttcact agtatttgag tagaagcagt atatttgtca
     6421 ggcataacaa agaaggttaa tgccgtactt actacaagac atattgccgg taaaataagc
     6481 aataatttaa tatttttctt tagaatattt aatagtttta ctaaatcaaa cttttctttc
     6541 atggtttcct ccacataatc aatcattgta ttcattatgt atgttttata aatcggacaa
     6601 ttatatctag tttaacgacc acaaaacata cacaactaca ttttctctaa ttatttatat
     6661 aaatatttta tcgtttaaaa ttatatcatg attctctacc gttatgtata acttatttat
     6721 atttttgtac aagatataat attgtccaac ttcaaatatc caaacctatt aataataaaa
     6781 ctagatacca tcgtactcta tcatggcttt cttataatcg agtagaagca tcatcattac
     6841 ttgattattt gctctttaca acaccgagcg tgcccgtact cggtaattca ataccttgcc
     6901 taacccgtca ctgtgagttg ggttaatgat aataaagccc acacctttta aaaagatgtg
     6961 ggtaatttat ataattttta tttacatttt taacttataa aaaaaagcgc ctatgtcatg
     7021 atttaccatc acataggcgc ttatcaataa attattactt attactttcc atttcatcta
     7081 atttatgcgg atttcctgta attagatgac aacttattct tttcagggga acattacact
     7141 tttataatat gttcaaagac aaacttaacc attcacaaat ataaagaata atattataaa
     7201 atcattgaac aaatcgtatt ttgcaacaat tgatatttat attaatgtat tgcatttaat
     7261 ttataaaatt catatacatc ttaatattct caatatcgat ttgtattgtc aactttatat
     7321 agatttaaaa aaataatctc atgtcttttt ttacaaaagt aagttaatta ttacaaacta
     7381 gtaacaaaaa ttatttcttc aaaaatatat ttagtagcga atacacttca tctttgaatt
     7441 gacttttact ttcttccact gctccaaatt tttgcgaaaa ggatgctttc aaataccaac
     7501 tttcaagaaa cagcaatatt aaattctgaa agtcttcttt tgtcatcttt atctttgatt
     7561 catcatagaa ttttgctatc tctttactta atgattgatt taaatcttgt atttgtccgt
     7621 aaatatttcc agaaaattcc tcaggcgtat tagataattg aacgtacatt ctaatatacc
     7681 tttcttcgat gtcgaaaata aactcaaata agaattgata taaagcatca attgaatagt
     7741 tcgatttatt ttgattcatc ataataatat tattaaggta atcaaaacag catttaacac
     7801 tttgttcgta aatacttttt ttcgagtcaa aatggtaata taaactcgct ttctttatat
     7861 ttacactttt agctatatca tcaagtgttg taccgtcata ccccttctct gaaaataagg
     7921 ttattgcgtt atcaataatc ttatccttca atttttataa ccccctactg aaaattaatc
     7981 acactatgtt acaggaaaat taagttgcaa ttacaaatat ttccgtttaa ttataacaac
     8041 aatctattgc aaattaaaat actatcaatt accatatggc ttacaaccta actaacgaaa
     8101 ggtaggtaaa gaaattgcaa ttttttaact ttttgctttt ttatcctgta tttatgtcta
     8161 tttactggat tgtcggttca atttatttct attttaccag agaaattaga tattcattga
     8221 acaagaagcc tgacataaat gtggatgaat tagaaggcat tacattttta cttgcctgtt
     8281 ataacgaaag tgaaacgatt gaagatacgt tgtctaatgt tcttgcactc aaatacgaga
     8341 agaaagaaat tattatcatt aatgatggaa gttcagataa tacagcagaa ctcatctata
     8401 aaatcaaaga aaataatgac tttattttcg tcgatttaca agaaaacaga ggtaaagcca
     8461 acgcactcaa tcaaggcatt aaacaggctt catatgatta tgtaatgtgc ttggatgcag
     8521 atactatcgt tgatcaagat gcaccatatt atatgattga gaatttcaaa catgatccaa
     8581 aacttggtgc agttacaggt aatcctagaa ttcgaaataa gagttctatt ttaggtaaaa
     8641 ttcaaacgat agaatatgca agtttaattg gctgtattaa gcgaagtcag acacttgctg
     8701 gcgcagtcaa tactatttcg ggtgtcttca ctctatttaa aaaaagtgca gttgtcgacg
     8761 ttggctactg ggatactgat atgattaccg aagatattgc agtttcttgg aaattgcatt
     8821 tacgtggata tcgtattaag tatgaaccgc ttgccatgtg ttggatgttg gttccagaaa
     8881 cattgggagg tctttggaag caacgcgtga gatgggctca agggggacac gaagtattac
     8941 tacgagactt ttttagcaca atgaaaacga aaaggtttcc tttatatatt ttgatgtttg
     9001 agcaaatcat ctcaatttta tgggtatata tagtgcttct atatttaggc tatttgttca
     9061 taacagcaaa cttcttagac tatacattta tgacatatag tttttcaata tttctactat
     9121 catcatttac tatgactttt ataaacgtta ttcaatttac agtcgcactc tttattgata
     9181 gtcgctacga gaaaaagaat atggctggac tcatatttgt aagttggtat ccgacagtat
     9241 actggattat taacgcagca gtagttcttg tcgcatttcc aaaagcatta aaacgtaaga
     9301 aaggtggtta cgcaacatgg tcaagcccag acagagggaa tacccaacgc taaaatcatc
     9361 gctaaatatt gtaagagaaa cagcacttat cgctatatcg tgtgtctttt ggatatattg
     9421 tttagttgtt ctactcgttt atattggtac tatatttgaa attcatgacg aaagtatcaa
     9481 tacaatacgt gttgctttaa acattgaaaa tactgaaatt ttagatatat ttgaaactat
     9541 gggcattttc gcgattatca tttttgtatt ttttacaatt agcatattga ttcaaaaatg
     9601 gcagagagga agagaatcgt gaagtataga aaattaataa ttttagtgtt gagtatcttg
     9661 atcatattgc ctgtaagcac actggatggt catcatattg caaatgcaga tgacgattca
     9721 cctaaaaaac tgaaatataa agaaaatagt gctctggcat taaattatca ccgtgtaaga
     9781 aaagcgaatt ttctgaataa ttttatttac ttcttttcta gtagtaaaga aattaaaaat
     9841 tatagtgtta gtcaatcaca atttgaatct caaataaaat ggctaaaatc acatgatgct
     9901 aaatttttaa ccttgaaaga atttttatat tacaagaaaa aaggtaagtt tccaaaacga
     9961 agtgtatgga ttaactttga tgatatggat gaaactattt atgaaaatgc ttatccaatc
    10021 ttaaaaaaat ataaaatacc ggcaactggg tttattatca caggtcatgt tggggaagaa
    10081 aactttcaca acctcgatat gattagtaaa aaagaactaa aagaaatgta taaaactggg
    10141 ttatgggaat ttgaaacaca tacccacgat ttgcataact tatctaaaaa taataagtca
    10201 aaattaatga aagcttctga agctacaatc ataaaagatt taaacaaaag tgaaaaatat
    10261 ctaactaaaa actttaaaaa gtcgcagaaa actatagcct atccttatgg cttgatgaat
    10321 gacgataaat taccggtaat caaaaaagct gggttaaaat acggtttttc attagaggaa
    10381 aaagcagtca ctccgaactc caatgattat tacatcccta gaatattaat tagtgatgat
    10441 gcttttgagc atttaattaa gagatgggac ggattccatg aaaaagatta gacttgaact
    10501 cgtatattta cgtgctatta tatgtgcaat tattattatc acacatttac ttacacaaat
    10561 tactttaaaa catgaaaata tggagggagg atccttagta ttacaatttt acattcgtaa
    10621 tattgtgatt tttggtacac cttgctttat tatcttgtca cagttactga caaccttgaa
    10681 ttaccaaaaa gtcacctata gatacttaac tacacgcgta aaatatatac ttattcctta
    10741 catattaatg ggattgtttt acagttatag tgaatcatta ttaacagatt caagtttcaa
    10801 taaacaattc attgaaaatg tcctattagg tcaatggtat ggctatttta tcgttgttat
    10861 catgcaattc tttattttga gttatatcat ttttaaaatt aactataacc tattcaacag
    10921 taaaatatta ttattgttat cttttatttt acagcaatca tttttatatt actttacgaa
    10981 caacacagcg tttcacgata ccgtgctaca ctattatcca ttaagtgaaa acactataat
    11041 attcggatgg attttttatt tctttttagg tgcatatatg ggttataact acgaacgtgt
    11101 attaaatttc ttagaacgtt atttagttat tatgattgta ttagctgtag ctacttattt
    11161 tgtgtttatt gcgttagcaa atggagacta ttggaacgtt accagctttt catattcatt
    11221 aacaccatat aatagtatta tgtttattgt tatcttgggt atttgcacgc attttaaaac
    11281 aatgttattt aatacgattc aaatgattag tgctttctca ttctttattt atttattaca
    11341 tccaatcatt ctagactcat tgtttgcata tacaaatata tttgaggata atacaatggt
    11401 ctttctagcg atatcactac tattcatttt agggttatgt ataggtgtcg gtatgatatt
    11461 gcgtgaattc tatatcttta ggtttattat tggaaaacaa ccatataaat tgaacattaa
    11521 tgcttattaa ttattaagct atgttaaaaa cacgcggtgg gcgaaatcag tttgaattga
    11581 ctgacttcgt tttaccgcgt gtttaataat gttatacata tattctaatt gcacatttaa
    11641 acttcgtaaa tgccaatggg agtgggacag aaatgatatt ttcgcaaaat ttatttcgtc
    11701 gtcccacccc aacttgcatt gtttgtagaa tttcttttcg aaattctttt tgttggggcc
    11761 ccgccaagat attacttgaa taattctttt agaattctaa ataatgatcc gattaattga
    11821 aagaagtctg ctgtcattgt atatacctcc ctttacttta taaattatgc ttgcttagta
    11881 tcagtcacct tttcagtttt cactaaatcg tctgctaaat gatgccaaaa atcttgtaat
    11941 tcttctcttg tgcgcactgt atcagaactg tcttgtccta caaagtcaac atgatcccaa
    12001 tcatgttttg taggcgtcac ttgccaaatg cctttttgaa ttttatccgt cgcatttgta
    12061 taagcttgat taaatggatg ttgagaagaa ataacggata ctaaaccatc gttttctcgc
    12121 cattcttttt cagttgcttt accgattaag ttaccagtaa tcacaaatgg gaaaaacata
    12181 tttaagtctg ctttttgtct atcgctattt aatgctttgt gcgttgcttc accagtgtat
    12241 gttttataca caatgttagg gttcaacgac gttttacgat ttaaatctgt tgcaccctca
    12301 cgcgtcagat cgtaaaatcc attatctttt gatttccata aattagattg tttaacgcgt
    12361 ttgacataat caatatatga ttcatttggc ttctgtttta gaccccattg agccaacccg
    12421 aagtctactc ttgaattttt attaccaaac attttaccga tatcaaatac gatttgtctc
    12481 actaaagctt cattaccagc taaatctgat gcgtgtgtac cattatgtgg tgttcctaaa
    12541 gtagtaattg atgaaatcat gttgtcatta ttacctttga atagtggaga aatttcgcca
    12601 ccatgtttct tttgatactc tatttcttca cgattaccat tacgcagtaa ttcttctagt
    12661 tgacgtatcg tttgaccgcc catactatgt ccaactaggt gtaccttctg tcctggtttc
    12721 cagtctttgt aaattccttc gtatgttttt ccataacgtt catgtccata ttttgctgca
    12781 tgtgctgcac cataatctac acgaccgcct ttgatataat aataaagttc aactgcgcgg
    12841 tcatagttac ttccaaaagc acttatactt gcttcataag ctttgtaacc attttcttct
    12901 aaatcttggc gaatgttcat tttattaccg ccccaataat gagctaacac tgaaggatta
    12961 atatcatctg taaacccatt gaaaccatgc actaaaacga taggatcttg atttttatac
    13021 tgcccttgtt tggcaacttt attcgtttga tcatctttcg cttttgcagt aagttccttt
    13081 gtccccttat tcggtaacgt ggctactgca ctacttttta ataaatttaa tccatttttc
    13141 ttgtcattgt cttttgttgg ttctactggt gatttttgat tgttttttaa atctgaaact
    13201 gatagtgttt tttcgtcttt ttgaggtttc acttcttgtt cattgttaaa attgtggtta
    13261 gtaattttat cattcgcttg attattttgt tgtggttgta ctttctctat ttctgtctca
    13321 ttaacaattt ctcgttgact tgtttgatct gacttattta atgatggtgc ttcttttgtt
    13381 aaactttgtg aaggtagatt gttattagcg tttgaatctt gactattatc tacctctttt
    13441 gactgttgct gtgacgccac tttactttgt ttgccatcat taatagcctg ttctaaccct
    13501 tgatttacat cgctaggatt agcattgtta ttttttgttg tatcacgttg aatattttta
    13561 ttattaagcg atgaattttt atcatccttt agttgatctt tattcaaatc atctgtttta
    13621 cgatgatttt cttctgatat tgttttatca ttatgcaagt tcttagttaa attttcagta
    13681 tgttgctgtt cgtcaacacc gttttcacgt tgataattag cattttccct agtttgttga
    13741 tccccaatag attgtgctgt aactgtatcc tcctgtgaat ttcccatatt cacttgcttc
    13801 tcagctgctt gtgcttgtcc accacttaaa aatagtaatg tagctattaa aatggaagat
    13861 gcacctacac taaatttacg aatactatac ttattttgac ttttcatcat tgtcagcacc
    13921 tctatttttt tagtttagat aaacaaattg ataattattc gaggaataaa ctcaaataat
    13981 ttacttaacc aagcactcat aatgaccatc ctttctattg tttaatttga cgagaaagcg
    14041 tttacatttg tatttaaaaa atatattctc caaagagaat ttaaagtgta tacgctaatc
    14101 atttcaaatt attaattaat attatatttg gcaaaattta attagtcaat aattagacac
    14161 aatttaatta tgcaaattgt aactttttta catatatctt ttgtgatttt taatatttac
    14221 atgcttgggt cttgattcca atgatgtatt atttttttag attagctgta tggagagatt
    14281 tatgagctat tacagttatt atgtttgctg gtgtcgtatt ttaaacctaa aaatatcatc
    14341 ccatccacaa tgattgtatc aggataaacc gtaatacttg ttcctacatt aaatatatac
    14401 agttaatttt cttccctcaa agtaagtatc ctactatttt taatttattg tttaattact
    14461 cttgaactac ctttaactta atctcgaatt tatgatgatt agcataaaaa tacaccccat
    14521 aaagttagtt ttttagtcta actttcggga tgcacatctt agttctaatg gagattgtct
    14581 tttaaatagg ctatgacatt tctatttcag gctagatata tttgtattta tagtataaat
    14641 acaaagaatg taaagacaac tatgatatta ataggtagta acgacaaaca taactcttta
    14701 gctttttcgc cattttttcc catcataact tcattatatc gattcatata cttttcgaca
    14761 tctttaacag tgacatctat tcctgagttg ctcaatttac ttttcataat tatttttgat
    14821 ttcgtattgt gattatccac tacttatcta taacgagttc gcaactttag taccatcaca
    14881 gcattcatag ttaaaatatg ttggtgtcgt attttaaact tgaaaatgtc acgttttcca
    14941 caatatttgt aagtgtataa gccatgatcc ttttccttat atcttagtcc atacttgctt
    15001 taccactgtt cgatattttg tcgttcacct ttaaagttat tgcgcttatg atgtctacgc
    15061 gctaattccg cctcaatttc tgaaaaatcg acgcctagcg catgcatcaa gacaaataaa
    15121 tgataaagtt catctgctac ttcacttaca aatgcttttt tgtcaccttt aattgcttca
    15181 attacgactt caaaagcttc ttcaccgtat ttttttgtaa tcttttctat accttctgtt
    15241 aataaatatt ttgtatatga cttttcatta ttggattggg cactatcttg aactgtctgc
    15301 gctaatgttt gcactgaaaa tggaacttct gtgttgaaac aactttgact gcctgtatga
    15361 catgttggtc catttggtat gacatcaatt aaaatagtat cattgtcgca atctacatga
    15421 atatctttaa caagttgcgt atgaccagat gtttcacctt ttgtccatag acgttgtttc
    15481 gaccgcgaat agaaacatac cacaccatct tctatcgttt tatcaaaagc ttcttgattc
    15541 atataaccca acatcaatac ttgttttgtt tgattatctt gtaaaattgc tggcactaaa
    15601 cctttgctaa aatcaatttt atatttggtc atcttactgc tataccccct tgccgtatca
    15661 cttctttaat tgattgaacc gtcgtttctc ggtcatgtaa tatacttgca gctaaacctg
    15721 cagaaacatc cgtctgatta aatagttcta caaagtgttg tgcattgcca ccaccaccag
    15781 aagcaatgat tggaatattt acaagggatt ttatttttgc aagatgctca atatcaaatc
    15841 cttgtttcat accatcatgt cccatacttg taacgaggag ctcacctgca cctaactgtt
    15901 ctacttgctg tacccagtca tatactttaa tatttgtcat ttttttacca ccatgcgtac
    15961 aacaataatg tgcttttctt tcaggatcat aatagctatc aattgctata cagatgcatt
    16021 gtctaccgaa tttatcactc gcttgtttaa tgagctgtgg attttttaaa gcacttgaat
    16081 ttaatgatac tttatctgca ccatgattta acaattgggt aatatcatcg agactttgaa
    16141 tcccaccccc tacagtaaga gggataaaca agcgtgacgc tgtctgttca atcacttcta
    16201 gcattaagct atgaccctct tccgtcttag agatgtctaa aaatactaat tcatcagcac
    16261 ccgcttcatt gtaatatatt gctaaatcaa caggattccc tatatccctt aatcctttaa
    16321 attgaatccc tttaacgaca cgaccatctt tgacatctaa acatggaatg atacgttttt
    16381 taatcattct agcccctccc aaaaagatgc ttgatgtgca gcctttccta taatagcagc
    16441 gtgaacattt agcgacgcta atcgttgaat atcttgctga tgtctaatac caccggaagc
    16501 aatgacagga atcgtcgttg cctttactaa ttgaccagtt aattcaaagt taggtccgga
    16561 cattttgcca tctttagcaa tatcagtata tataatgcct ccaagaggta tatccgataa
    16621 ctgtctcaca aaactaaata aatttaactc tgtgtcctct tcccatccgt tcactttaat
    16681 atcttctcca taagcatcaa ctgacagata aatacgacct ggaaatgtat gtgccatctc
    16741 tttaagccaa tcagtatctt gaatgccttt cgttccaact atgcaataat taatccctgc
    16801 ggcaaagtag tccatgattt gtgacttcgt acgaatgcca ccacctactt caatatcttt
    16861 ggttgttaat ctcctcaatg acttaatata atcaaactct cgggcatact gtgccttagc
    16921 acctatcaag tcgacgatat gaatacgatt cacacattca aattgactat agtaagcaat
    16981 actttcttca gccgaacgcg acattttttc ttcactatca tatttaccct ctgttaacct
    17041 cacacttgtt gacccaatca aatcaatcgc tggccataat tcaatcattt ataaatcccc
    17101 cttgtattgc ctgacgcaaa atttgtaacc catatgtacc gcttttttca ggatggaatt
    17161 gaataccaat ataattgtta aattgaacaa ttgccggaat atcagcccca tactgcgcat
    17221 atgcaatgac attttctgac atcggcgctt ggtaagaatg tacgaagtaa acatcttgat
    17281 ttaacatagg atgcttactc actaaattat tccaacctaa gtgcggcact gggtattctg
    17341 tttggatacg cgaaatattt cctgggataa accctaatcc agatgcatcg ccttcatcac
    17401 tatgctcata cattaattgc atgcctaaac aaataccaat catcttctta tcagtattct
    17461 tagccaatat tgcattgaga tttaatcgtt ttatctctga catcgcatct ttaaaatggc
    17521 cgacaccggg caatatgatt gtttctgctt gatcgattat ttttgaggta tttgagacaa
    17581 ccacctcata ccctaaatgt tcaatagcgc gttttacatt actaatattc cctaatccat
    17641 aatcaacgat gacaatcatt caatcacacc tttcgatgac ggcacacgct gatcatcagt
    17701 tgcagttagc gctatgccta atgcacggga aaacgctttg aatatagctt caatttcatg
    17761 gtgtgtatta cctccacgaa ttaaatcaat atgcgttgtt aatcttgcat tgattacgac
    17821 cgctctaaaa aattcttcta ctaactccgt atcaaacgta ccaacttttt ctttacttaa
    17881 tgatgcattg aatgataggt atgggcgccc acttatatcc acaacgacac gtgctaatgt
    17941 ttcatccatt ggaatgtaca tcgttccata acgaacgaaa tgctttttat ctttaatcat
    18001 ttcaagtaac aattggccaa tgacaatgcc gatatcttca gttacatggt gatcatctac
    18061 gtcaatatca ccttgtgcct caatgtttaa tgacagaccg ctatgaaatg taaacaatgt
    18121 taacatatga tttaaaaagc ccacacctgt attaatatgc gatggtgact ggtcatctga
    18181 tattgaaata tttagttgtg tttcagctgt gtttcgttgt ttttgataaa tcatattttg
    18241 cgctccattc tttaacaatt tcttctaatt gctttaactg cgatgctgtt gcaattgagt
    18301 atcttacata gcccttcatc accggctcat cataaaagcg aggtttaaat ccttgttcat
    18361 atacgtattg tcctaattgg tgcgctgctg aacctttagt aagtacaaaa ttggcatttg
    18421 atgggaatac tgacatttta tctgcaacat gtgtatcaaa tatttgtttt aactgctcag
    18481 ctaactgtcg ttgcatcgtt aaaaatactc ttgtctcttc tctatgtcta aaaatataag
    18541 tcgcaatatt tagcgtaaat acatttaatg gatatggatg ttctattttt tgaatatgct
    18601 ttatcgttcc agcagtacta attaagacac ctaatcttaa gccggcaatt ccaaacgcct
    18661 ttgataatgt acgcattctt aagatgtgtg gtgccagttc cacgtcatat gccgtaccat
    18721 aatctaaata tgcttcatca atgacaaagt atccgtttaa tgctttcatc ttatctgcaa
    18781 tagctgttaa aaatgccgta tcaaattgct tgcctgaagg gttatgtgga ttactcataa
    18841 taaaaaatga tggttgtact tcatcgattt tcgttaaaat ggtttccaaa tcaaacgtta
    18901 aatctgatcc tgcatctaca aatgcaattt cacgatttac ttgtgccgca tatgcttgat
    18961 acataaaaaa atcaggattt agcgttaatg ccggaccttc tggcatgatc agcattaact
    19021 tttgaatcaa ttcatcagat ccatttcctg caataatttg ttcaggcgat aatccgtaaa
    19081 acttagcata agcttccttg aattgttcat atgctgcatc aggatataaa ttatatggcg
    19141 ttgcactaat aatagacgtc attgtttttt catccaacgg cgtaactgga ctttcatttt
    19201 tatcaatata aatcatttca attacactcc cctaagactg acgtattaaa atagactgct
    19261 ggtgattgta taatgcttca acatgagcaa tatgttgtgc tgaatcagca atttgttcaa
    19321 acgtatcttt tgataaatgg atgaccgtgt tccgtgttaa gaaatcattg accgataacc
    19381 cattggtaaa tctagctgtt ctatttgtag gtaatacatg acttggacct gcaacgtaat
    19441 ctcctatgac ctctggcgaa taatgtccaa taaacaatgc acccacatat ttcacttttt
    19501 caatatatgg ttgaggattt actgtttgaa tcgacgcatg ttcaggcgcg attgtattca
    19561 tgacatggca tgcttcatca aaattactag catggataag gtagtgttga ttagcgatac
    19621 ttttagaaac aatgtcgtat ctgtccacat taggcaatgc tttagcaata cgtgattcta
    19681 aatctttaag gacttgcgca tcttcaccaa tgacatatgt acgtgctaat tcatcatgtt
    19741 ctgcttgcgc aaatacatca tatacgatgg catctaaatc tgcggtgtcg tcaataatca
    19801 gtgctatttc tgttggtcct gcaatttgat caatacctac ctgtccaaat aaatattttt
    19861 tggcatatgc aacaaattgg ttacctggac ctacaatctt atcaacttta ggtatcgttt
    19921 ctgttccata agtcaatgca gcaatacttt gagcaccacc aacttgaaac acttgattaa
    19981 cttgcgtaat ataacatgca gctaatacct cttgggatac tccgttaggt tgaggtggtg
    20041 tcacaacaac aatattttct acacccgcta cttgtgctaa agtcgctgtc attagaaccg
    20101 ttgatggata acttgctttg ccaccaggca cataaatacc cacactttct agtggatggt
    20161 atatttcata acactccact gattcttcta actgttgatt cgtctgctta atactttctt
    20221 gatatgcttt aattctttca taactttgtt gtaatgcttg ttttgttttt tcatctaatg
    20281 tgtcaaatgc tgctttaatt tgttcatgac taatttctaa atgatctgtt ttcgtatgat
    20341 cgaatgttag attatacatt ttcaaagcct tatctccatg aactttaact tcctgacaaa
    20401 tatcgcgaat aattggatac aatgactcat ctaatggtgc ttctaatgaa aattgattta
    20461 aaaattgttg tgcattaagc attggcaata gacacctcca aagagcgaat aaattgctct
    20521 attaattgtg attttttaaa ataagctgct ttattagtta ttaatcttgc attgatatca
    20581 ctaatatgtt gcttttcaac cagtccgttc gcttttagcg tagtacctgt ttgaacgatg
    20641 tcgacaattc cgtctaccat atctacgaca caagctaatt caacagaacc attcaattta
    20701 atcaattcga catcaatacc ttttgattta aaatatgttt cagcagtatg aacataactc
    20761 gttgcgattt tacgataatt ggtcgtttca ggtttcgctg caaccgcaaa atgacatgct
    20821 ccaaaaggca tattcaacaa attattaaca ttatattggc gctcatctaa tatgtcgcta
    20881 ccaacaatgc ctatgtcggc cattccttgt tccacataga ttggcacgtc acttcctttt
    20941 actaaaatgc attcaatatt atctacactt aataataatt ggcgttctct attttttaat
    21001 gtttctgata atgtcgtata ttcaattaca tctaaatagt taattaaact atccattaga
    21061 cgtcctttgg ctatggcgat tcttaacatt gtgcatactc ccttacttaa agtgttaatc
    21121 ctaatccaaa cccttcgatg cttcctttgt aataaccacc tgttaaaact cgagattcat
    21181 tttcagcaaa atgacattga ataaataagc ctgtgtaata ggatctaggt ggctgcgcag
    21241 taatatctaa atggatgtct ttgtaacctt gtgtatgtaa ccaacgttcc catattttta
    21301 attcaacgag tgctggatgg tcatttggaa tatagtgttc caatacattt aattgttgtt
    21361 gcgtattctc tttcaagatt tgcacgattg gatgttcagt cgacaaatat gtaaccagtc
    21421 ccgataaatt acgttcctca atcattgata gtatgtctgg tgtttgtaac gatttatcga
    21481 gtaaggcatc aagcaattga taatgtccca atacaacaaa atgcacgttg tctctcaact
    21541 gctgttgaat aaactgaata aatagcttta agctctgttg tacattcgct aatgatggtg
    21601 catagttttc caaacccact tgtacagccg cttcattatt ccgaatgatt aaacctgtgt
    21661 atgccacttt tgttgctgca gttggataca ttgagtaata acgcaataat tgatctgtaa
    21721 aatcatttcg aagtgcataa atttgatgct catgttgcca aaaatttcgc tcacccatct
    21781 gctgcaaatc ctcatggttc aattgtttcc agtccaactt ttcaaccaca ctaaaatcaa
    21841 ctaactcata atccgcttta ttaaaatatt ttaaaaatgc tgtttccgat tcttttaacg
    21901 caattaattg ttctgaatta ttcactcgac caccctttac tttcaatact gtatttaaaa
    21961 tcacttggta ttttcgttgt ttactttact tctctaccac actaaagtgt aatatgatta
    22021 ataacttatc atttttagca atacattaca acctttttca gaaaattcgg tgtattgttt
    22081 ttaaattttt acaaaagaaa aaggcaagac atttgtgcct ataaaaatgc taaaccaaga
    22141 tttttatatt gaagttgtac ttcttgcaca tattgtgctt gccttattat gtaaagttat
    22201 tttctttcta tctttttatt aaatttaact attcttcata atcccgatta cctttaaaga
    22261 attgtctatc ttgtttacta tatacatttt caggattaaa aaacggtttg agtttatatt
    22321 taaattcaaa taagtttaga ccatcaatcg caaccctatc ttggtaaacg ttcgttgctg
    22381 atatatctgt aaaattgttt ggaccgacac ctgcaataaa cttaaactct gcttcatcta
    22441 ccaaataatc atacgcttgt gtatgtctat cctgtgcgcc atgtggaaat acaaacatat
    22501 ctgttttacc tacaattggt tcaacttcat ctttccatct tttagtatca cgtttaatac
    22561 cttctaaaga tgttttttca aaattaatgt gaccatatga atgactcgca aatgaccatc
    22621 catcccgttt cattgcgcga acaacttcct cagctgcctt tttattcttt gtataatctt
    22681 tactcgttaa ttcattcgtg cgataaccta atacgccctc ataaccggtt aaagcaacaa
    22741 cacctttttc accatttaaa gaaaaatctg gatgctcttt tacaaattta tttaaaattg
    22801 gcacgatatc attgtcatca gaataagtag catgaccttt tttgtctgta gtttcagaaa
    22861 caacatgttt atttttatcg agtactaaac ggtcagcata accatggtgt ctcatgtaac
    22921 tatagtaatt catatcatca attgagatga ttagtggctt tttacctttc ggcaatttta
    22981 tttttttggc ttttacatga tgagatgata agtcgtatac atcatgtgga ttaacgatga
    23041 tgtaattatt tttatataat tcgttcaatg attttttaaa ttcacttaca gtaatcatcc
    23101 aatcattgtt gcccttagct tggtgtgtat ctcctgtaaa cgcaactttt gggtctgtaa
    23161 ttaatgggtg ataaaacaca tgataaactt ggccgtgata tgtttcccaa tgttcatcca
    23221 ttttcgattt atgctttgca tactcatttg gattaacaga tttattttga gctttctcat
    23281 tttgcttgga acagctatat agcaatgcaa ctgataataa cagaaaaaat agcaataaat
    23341 attttttatg cattaaacat tctccctatg ttttattatg cacaattata acatttttat
    23401 tatgtggctc ataacttttt aagaaactgt tgggatttta attttatttt ttagataatg
    23461 tcatagtatt ttatttataa aacacaatat ctccttgatt gataatgtcg tccatagctt
    23521 tgtctcgctt gaatttaagc ctttctgcta aatttattga acgttggtta cacttatttg
    23581 tcctgataac ttttactgtt tcttgatcga tataattcac aaaatttgtg attgctgtaa
    23641 tagcctcaca tgcgtaccct tgtccttcaa aacttggatg taatttataa aataaattta
    23701 gtactgtttc ttgctttaat tgtcgatatt catatccaca aataccaata acactacaat
    23761 ctattttttt caccaataca aagtaaccaa attgatattg ttgccaatgg ttttgccatt
    23821 tttcaatcca ccgttgtgtg tctaatttgg aattatgtaa acctttggga gtgtatatat
    23881 ttgcttgtgg atgactacaa atattataaa gttcaattaa atgcgaggaa cttggaatca
    23941 ttaaatttaa tctttcagta tttatcatta aatgtctccc tcctatttct atttaaagac
    24001 tatttatatg aatactaatg ccacgggttg aaatatcgac tattatttaa aaagaataat
    24061 gtaactacta acatcagaag tattaacgtc aaacacaaaa caacataatc atcttttttt
    24121 aattgttttt tgacgtacca ggttctcctt ttatactgtc cgaattgtct taactccata
    24181 gcagtactaa tagtgtcaat tctttcgata ctagaaaata ttaaaggtaa cacaatgcgt
    24241 ttgatacctt taacacggct agtaaatttc gcttttttcg aattatcata tcctcttgct
    24301 tgttgcgctt gtgaaatatt aaaatatgtt tcttgaatat ctggaatata ccttaatgct
    24361 agtgagactg cgtaactgat tttataattc acacctagct gatttaaact tgcagcaaaa
    24421 tgactcggat tcgttgtgaa taaaaatatt aacgctaaag gaactgtact aatatatttt
    24481 aatattagat taaaaagata gaataattcc tgtgatgtta gcgtaaatcg accaatacca
    24541 ttgactaact ctgtacgctg attataaatc ttcacaccat attcagggtc aaatatgtat
    24601 acggcaataa tatttaatat tgtgaaaaac agaatgaatt taacaacaaa gcgaacttgt
    24661 ttccattcaa tatgagcata tttgaacaat aaaatagatg aagcactaat taaaattaaa
    24721 tatcttgtgt cataagtcac cattgcagaa atagaaacaa ctaataagaa taaaagttta
    24781 acagtcgcat ttaattgatg aatacgacta tttcccgggt gaaaacctat agtattatat
    24841 tgattcattg gcgtctcacc ttcctatcat ggttaataaa taattgtact aatttctgtg
    24901 gctcgctaat ccctatatat tcggccattt caaatagcga tgtttgtctc aatgatgcaa
    24961 tctcacagat ttttttatca tttaatatca atactggcgt ggtatcagca acgacttgtc
    25021 cttttgataa tacaactgtt cttgaactat actcagacaa taaatgcata tcatgcgtaa
    25081 tcataataat cgtctttccc tgtctgttta gctcaattaa aaatgacatt atctcattat
    25141 aatgatagac agcagtcggt tcatccaata tgattatttc cggatttaag actaaaacag
    25201 atgctatagt gaccctcttt ttttgaccat agcttaaagc tgcaattggc caattccgaa
    25261 atgcataaag tccgcatatt ttgagcacat tctctactcg tatctttata tctgattctt
    25321 tcatacctcg tgctcttaac cctaatgcta cttcatcgta aatcattttt tcagaaatca
    25381 tatgatttgg attttgcatc acataaccta cgaattcaga tcgttcgcta attgacaatt
    25441 gattaaatcc cctattacaa aattggatat tacctgttat atctaaaaat ccacaaattg
    25501 ctttagcaag tgttgatttg ccggcaccat tgtgaccaac tatactaagc atttctcttc
    25561 tataaacatt taattgaaca ttattaagta cactattact atagtcacta tattgaacac
    25621 atacctcatt taattctaat agcggttcag atttgtactt attatcatta tttgcagatg
    25681 tttcatctat ccattttttc actttaaatt taacatgttc actcatacaa acgtcacgta
    25741 aattcgctaa gttatcaatg gattcgacat ctacttctgc atatttaagc gctgtacagt
    25801 ataatggttc acgtatgcct gcttctttaa gcttagatga ttttagcaaa tcactaggcg
    25861 ttgtattagc gatgattttt ccatctttaa aaagaagaac tctatcaaac gtatcatcta
    25921 atgattcttc taatcgatgt tcgacaataa tcatcgttga ctttgtttct tcatgaatat
    25981 tgtttaacaa tctcagcgtt tcatgtcctg tcgcaggatc taaattggcc agcggctcat
    26041 ccaatattaa aataggcgta cgatggatta atataccacc taatgaaacg cgttgttttt
    26101 gacctccaga taaatcttgc ggtcggtgat ttaaatgttc tatcatgcca actttttcag
    26161 cccaataact tacatttttc ttcatatcat cttgttcaac acaattattt tctaataaaa
    26221 aggccatatc ttcagctgct gttaagccta tgaactgtcc atctgtatct tgtaaaactg
    26281 taccaacaac attagatcta tcatgtaaac aactaacggt tgcatcttga ttatttatat
    26341 atagttcccc ggttatgtta cctttagttt taaatggaat taatccgttt atgcaatttg
    26401 caaaagtcga tttaccacta cctgaagcac caactactag cactttttct cctggataaa
    26461 tatcaacatt tatattctgt aatgtaggtg ttgcttgact atgatattga aaactaaagt
    26521 ctttgaacga gataattggt tcagtcatga tatatcatta cctttctaca ttcatttaca
    26581 tatctgattc aacaaaatga ttattcttta cgtaaactac ctttttttat ttgagatgaa
    26641 gcatatgctt ttaataatat tgtcccaata ataccaactg aaataatatt taatactgca
    26701 gagataacac cttgtgtata aaccttgtta gccggttcgt tataaatcaa aatatctaat
    26761 gttggtgcaa taagtgccca gcaaataata ttcgcaataa tttgaccgat attaaaataa
    26821 atcatcgatt tcctagaaaa taggcctgaa gaaagattta attttaggcc aatccatcca
    26881 tataaacagc ctataattcc tgaacaaata acccaactcc accaagcact accgtatgtc
    26941 gtgaaatctt taatagcgtg tccaactaat ccagtcatta aaccagcaaa aggcccaaat
    27001 attgcagata ttaatgctaa aaatgcataa gatgtttcta tattcgtatt aggaaaacct
    27061 gttggtatta caacaaaacg ccctaaaatc acaaataccg ctgctcctat accaatcgca
    27121 acaacagttt taactgaaat atcttgtttt ttcatcttca ttactcctta cataaaaaat
    27181 tcattaaatt gatggtgctt tagataaatg aatcgtccaa tcatttccag taccaatatg
    27241 atataaatct gaaaatgagt cttgattgac tgctacacca atatttacta gcgagttaac
    27301 atacacaaga ggttcaccca cattaacatc tgcaaacgat cgcgcaaatt taataatatt
    27361 ttgatagact ttcttatctt gatgataaat tgttaccacc aaattattac catgaacaat
    27421 ttccaaggat tttaagaatg ccaatggaat atttgtccat aatgacccaa atctgatatc
    27481 taaaatatca atgcttcctg taacagaatc ctcatttttt gtcgcttctc ttatttctaa
    27541 tgcctcaata ctatcaacat taattgcctg accgagacgt tcaaacgcta tcttatttgc
    27601 agctaatctc gcaccattgt atgcataaac atctctacca tgaaaagtat gactttcttc
    27661 cgaatgaggc aatcggcttt tcacttcatc aatttcgata acttttttaa taccttcgta
    27721 atgtttaata tgacttaaag aaccattatc aggtgtaata atgtaatgac ctgaatatgt
    27781 taagcaagca atgctccgcc tatcactacc tacacccggg tctaccactg atacaaaaac
    27841 tgtgccttta ggccagtatt ttacagtttg atataaacga tatgacgcta cccaaatgtc
    27901 atacggtggt atatcatgcg ttaagttttc gacacgtata tcatcactta cagtatatgc
    27961 aactccatac attgcactta cagcgccatc actaagtcca aaatctgatt gcaaaaccaa
    28021 ataatttccc ataaaatgcc tcctttttta aaacttcaaa aaaatataat ctacatattt
    28081 aacgttctat attttgaatt ttcagaatta tattaaaata gtacgagtca cttgatgcaa
    28141 agtcaatagt agtgactata aaaatgataa taatagtcag atttatctca ttaactaaat
    28201 ttcacggact tgtaatcact tctttatgtt tgaattaatt gactagggta taacaatagt
    28261 gtggtgtttt ataggtcatt ctttaaatac atcacagaaa atattcgaat tcgaaataaa
    28321 atgcttgcat ctttgttttt taggtggtat tgtatgtata tcaagtataa aaaatatatc
    28381 taagagataa aaatatggag gttttatatt atgactaact ttacttttga tggtgcacac
    28441 agtagtttag aattccaaat taaacattta atggtttcta aagtgaaagg ttcatttgat
    28501 caatttgatg tagctgttga aggagatatt aatgacttca gtactttgaa agctactgca
    28561 acaattattc caagctcaat taacactaaa aacgaagcac gtgataacca cttaaaatct
    28621 ggtgatttct ttggtactga tgaatttgat aaaatcacgt ttgaaacaaa atcagttact
    28681 gaaaacaaag ttgttggtga tttaacaatt aaaggtatca ctaacgaaga aacattcgac
    28741 gttgaattca acggagtaag taagaatcct atggatggtt ctcaagtaac aggtgttatt
    28801 gttactggta caatcaatag agaaaactac ggcattaact ttaaccaagc acttgaaact
    28861 ggtggcgtaa tgctaggcaa agatgttaaa ttcgaagcat cagctgaatt ctcaatctca
    28921 gaataatctc attacacaat cctcattgtt ttaatatata tatacgaaat gccaactata
    28981 tcatccctag gtatagttgg catttttcgt ttaactcatg tgtaacaagc actaactgtt
    29041 caccctaatt taagacgcct ttcattcagg taggtcttat tgaaactgaa aactttgatg
    29101 accttttgca aagccattaa ctgtataaag catagatcct ccgcccattt ctatatcatt
    29161 ggaacaaatg atgagttgat ttgttccagg tataaattgc ggatgagtag aacgtaacat
    29221 atgcccttca tctcggcctg gtatcaatat ttgtcctatt ggataacccc ttttattaaa
    29281 aactaacact cgaccttgac catacattgc tacgtataaa ttatcgtcac tatcaataca
    29341 acatgagtct ggtccttcat gacctgtaaa atagtacggt atagtagctc caaatggttg
    29401 tatcgtcaca ccatcatctt caagtgcaat gcgatgtaat cgattggctg tagtttctgt
    29461 tacccatagt actttttcat ctgtacttaa agcaatacca tttgctacgc taatattttg
    29521 aatgataggc gtcactgttc taaagtccgg cgaaacataa taaacgcctc ctagtggatt
    29581 ggtagagtat cctctaaaat ctgtaaaata aaatccacct ttagaatcaa ataccatgtc
    29641 atcaatacaa tatgctgttg aaagatcttc aataatatct tgtaagttgt caccattttc
    29701 tgtagctgca aaaatgcctc ctgtagattt aaaatctcct aaataacaaa cgaataatcg
    29761 gccatcttta tgtattttga ttgctgcagg attcgctttg tgacttacaa aaggtcgttt
    29821 gatttccttc gtttcaggat tgattttgaa aatattgcct tcgaatacat ccaataaaaa
    29881 gagttgtccc tgccgatcaa agttcaatcc ttctagttgc aatccttttt tggaaatttc
    29941 aagccatggt tcagctgtaa ttgtttgtaa ttcactttca gatataattg gaacagcact
    30001 attggacttc ccgctataaa ataatgtagg taaatcttgt tgtgacatca tgatcattcc
    30061 tttcatttca ttcgttttaa ctatcaattt tattttaaac aagataacta tcaaataaaa
    30121 tgataacggt ttcatctatc tattttatcg gtctagtggc tgatttcaag ctagaaatat
    30181 tgaatgacaa tacaactctg ttaaaatgat ggacgtagat aaatatgcgt attgacgctt
    30241 tattttaaaa attaacatgc ttataacatg tttatagaag gagattaacc tatgaactat
    30301 caagttcttt tatattataa atatacgacg attgatgacc ctgaacagtt tgctcaggat
    30361 cacttagcgt tttgcaaagc acaccattta aaaggtagaa ttcttgtttc tacagaaggt
    30421 attaacggca cattatctgg tacaaaagaa gaaaccgaac aatatatggc acatatgcat
    30481 gccgatgaac gattcaaaga tatggtgttt aaaattgatg aagctgaagg acatgctttt
    30541 aagaaaatgc atgtacgtcc tcgaaaagaa atcgttgctt tagatttaga agatgacgtc
    30601 gatccaagac acacaactgg ccaatattta tcacctgtag aatttagaaa agctcttgaa
    30661 gatgatgaca cagtcattat tgatgcacgt aatgattatg aatttgattt aggtcatttc
    30721 cgaggtgcaa ttcgcccaga catcacacgc tttagagatt tacctgactg gattaaagag
    30781 aataaagcgt tatttacaga taaaaaagtg gttacgtact gtacaggtgg cattcgatgt
    30841 gaaaaatttt ctggatggct tttaaaagaa ggtttcgaag atgtagcgca gcttcacggc
    30901 ggtatagcta catatggtaa agaccctgaa acaaaaggtc aatattggga cggtaaaatg
    30961 tatgtatttg atgatcgtat cagtgttgat atcaaccaag ttgaaaaaac aattattggt
    31021 aaggattggt ttgatggcaa accatgtgaa cgttatatta attgcgctaa cccagaatgt
    31081 aataaacaaa tattagtttc tgaagaaaac gaaactaaat atttaggtgc atgctcttat
    31141 gaatgtgcta aacatgagcg taatcgttat gttcaagcaa ataatattag tgataatgag
    31201 tggcaacaac gtttaacaaa ctttgatgat ttacatcaac atgcttagtt ttaattaaat
    31261 acctttcaaa acacgctttg aaaatccgat ttataaaggt ttttcaaggc tgttttttat
    31321 gcgcatacat aacctgatat gtttttaatt atgcgcgtgt tatactaaat taaattttaa
    31381 tactgcgggg tgtcttaaaa tgcacatttt agtaacaggg tttgcgcctt ttgacaatca
    31441 aaatatcaat ccctcatggg aagctgtgac tcaactagaa gatattattg gcacacatac
    31501 aatcgataaa ttaaaactac caacctcttt taagaaagta gataatatta taaataaaac
    31561 gttggcatct aatcattatg atgttgtact agctatagga caagctggtg gtagaaatgc
    31621 cattacccca gaacgtgtcg ccattaatat tgatgatgca cgtattccag ataatgatga
    31681 ttttcaacct attgatcaag ccattcactt agacggtgcg ccagcttatt tttcaaattt
    31741 accagttaaa gcaatgactc aaagtattat taatcaagga cttcctggag cactttcaaa
    31801 tagcgcaggt acgtatgtat gtaatcacgt gctttatcac ttaggttatt tacaagataa
    31861 gcattaccct cacctacgat tcggatttat tcatgtgcca tacataccag agcaggtcat
    31921 tggtaaaccc gatacaccat ctatgccatt agaaaagata gttgcaggtt tgactgcagc
    31981 cattgaagct atttctaatg atgaggattt acgtatagct ctaggcacaa cggaatagtt
    32041 ataaatgcac aaacaaaagc accctaattt gttagtttaa gtctaacttt agggtgcttt
    32101 tggatgattg gtatacagtt ttactataat gatgtatttt agctaaacga cattgtttag
    32161 tcttcttttt ttaacttcct aaaatttaca aatgtataaa taataaatgc tatatttaga
    32221 atgatgagta tacttactga aactaaatta aaagtgtctg gttctttact aaagatagct
    32281 gctatccttg ctatcaaact tggcaatgaa attaccaaca cgatgagcgc ataaattttc
    32341 tgtttaatta aaatacaaat tacaataagc gcaattaaaa gtactaaccc aacgatgaaa
    32401 ctctgtttgt cacttaactc aaagaaacta tagataggat attttttaat aatcaaacca
    32461 ccaaaaatca tccataaaaa tacgacaatt ccataagtca catttataac atacgttatt
    32521 ttttggtcac caaatcggac taatgtattg cgtagaatca gcataccaat gacaacacct
    32581 aaaataacga tactagctat ataaagtaaa aatgcaattg tcacatcaaa tgtacccaaa
    32641 tctaaaaacc taggaattat aatgactgct aatataaaag agaagtacaa agtaatatat
    32701 ttatacaaac cggtagtaag acttatctca ggtgataatt gatcagccat tgacttaatc
    32761 ggtgtattaa taattgaact tgtatcttcg ttattttttt cagccatagt taaatgatct
    32821 tcgagctctt ccaataactc ttctacttct gcttcagtct tacctctaaa taacaattca
    32881 acacgtaatt tttctaaaaa atcttgagat tgtttagtta acatcgtttt cccctccaaa
    32941 caagttaatc atccctttat tcaaagcttg ccattttgat ttaaatactt ttagttcctt
    33001 taaacctgaa tcggtaatcg tatagtattt ccgcctcggg ccgccattac tagatttttt
    33061 tattgtcgta tcaacgtatc cttttttgtt taaacgcatt aaaactggat aaatactacc
    33121 ctcacttatc tctggaaact cttgattctt aagtttcgtc ataatttcat atccatacgt
    33181 ttcgccttgg gcaatgagac ctaatatcgc cccatctaag agacctttca taatctgatc
    33241 tgacactgac attttaatca cctactatct tacataataa gatagtacat tgagaacttt
    33301 tcgtcaacta tcttttattg taaggtagtt gttgtacaca ttccttaaat gactaacaac
    33361 tttgttaata gggtaatact tacggaagta tgttttattt atgggggagg aattaataat
    33421 gactacaaaa acagtatttg atgtcattga tatggggtta ggatatttag taaatgtgta
    33481 tgatgcttgg aaagttgaaa aggtacttga tgattatcat gagccttttt ctaataccat
    33541 tcattggcaa tttgggcatg tattaacaat ttttgaatcg gccttagctg ttgctggtaa
    33601 agagaatatt gatttaaata tctatagacc tttattcgga aatggttcgt ctccagatga
    33661 atggaaggat gaagtaccga gtattgaaaa gattttagaa ggtctccaaa cattacctga
    33721 acgtgcacga aatctaactg aagatgattt agcaattgaa ttgaaacaac caattgttgg
    33781 ttgtaataac ttagaagagt tattagtatt aaatgccatt cacatcccac ttcatgctgg
    33841 taaaattgaa gagatgtctc gtatattaaa aaatttaaaa taaatatgtg cttattaacc
    33901 gttaacaaca cgttaacggg ttttttattt gtttaaaagg ccactttttt gaatttaata
    33961 aacaccatct ataccagttc ttcaccgctt ctcgaaaaat aattatatta atgatttcgt
    34021 taatttaatt ttatatttaa ttattactgt acatcttttg tagttagctt tattcttaaa
    34081 ttgaaatatg tataaaacat agaaagaagg acgttttaac atggaaaaca cggttaaata
    34141 tcgtaagttt atactcccta tcgttgtagg tctccttatt tgggcactta caccttttaa
    34201 accggatgct gtggatccaa cagtatggta tatgttcgca atattcgtcg cgacaatcat
    34261 tgcttgtatt acacaaccga tgccaattgg ggccgtctct ataattggat ttacaatcat
    34321 ggtactcgtt ggcattgttg acatgaaaac ggctgtcgct ggttttggta ataatagcat
    34381 ttggttaatt gctatggcat ttttcatttc gagaggattt gtgaaaacag gtcttggtag
    34441 acggatcgca cttcatttcg tcaaattatt tggtaaaaaa acattaggct tagcatattc
    34501 tatcgtcggt gtagatttaa ttctagcgcc tgctacaccg agtaataccg cgcgtgctgg
    34561 tggaatcatg ttcccaatta tcaaatcact ttctgaatca tttggttcga aaccgaaaga
    34621 cggatcagca cgcaaaatgg gtgcatttct tgttttcaca gaattccaag gtaatttaat
    34681 tactgcggct atgtttttaa ctgcaatggc cggtaacccc cttgcacaaa atttagcatc
    34741 tagcacatct aatgttcaca ttacatggat gaattggttc ctagctgctt tagttcctgg
    34801 acttgtttcc ttaattgttg taccttttat tatttataaa atttatccac caactgttaa
    34861 agaaacacca aatgctaaga gttgggctga aaatgaatta gcgactatgg gtaaaatcgc
    34921 tttagctgaa aaatttatga ttggtatttt tgtcattgct ctaacattat ggattgtcgg
    34981 aagtttcatt catattgatg caactttaac ggcctttatt gcgctagcat tgttattatt
    35041 gacaggtgtc ttaacatggc aagacatttt aaacgaaaca ggtgcttgga acacattagt
    35101 atggttctca gtattagtgt taatggccga ccaattaaac aagcttggat ttattccttg
    35161 gttaagtaaa tccattgcta caagtcttgg tggcttaagc tggcctatag tactggtcat
    35221 tttaatattg ttctacttct attcacatta cttatttgca agttctacag cacatatcag
    35281 tgcgatgtat gcagcattac taggcgttgc catcgcagcc ggtgcaccac cattattcag
    35341 tgcattaatg ttaggtttct tcggtaacct attagcttca acaacacact atagtagtgg
    35401 tccagcgccg attctattct cttcaggtta cgtgactcaa aaacgttggt ggacaatgaa
    35461 cttgatctta ggtttcgtct actttattat ctggattggt ttaggatcac tttggatgaa
    35521 agtaattggt atattttaaa atatttaaat tagtgctcga atctcattga tttgggcgct
    35581 ttttaatttg tatttaaaat caacctttgc taaatcaaga ctcccttttt aaaatacgtt
    35641 tatcctttaa atcattgcgt gcttcactga aaatttgtat aaagatttaa gtcattacgt
    35701 aacatcacat aaaatacatt tctatactat tccgtttcat tgatcaacat tacgtatgcc
    35761 ctcataaatc atgaaataaa aaaacacctt cgtttaaatt cattttaagt gcgaattcaa
    35821 cgaaagtgat ttatttcata ttcaatgttt taaatttata cagctgtcac tgttactgca
    35881 cacatacctc agtctcacct tatcatgaca caaaggatat tgaaaacacg tataattatc
    35941 tttcctcgta ttttataggg tttttgcgac cggatgtttc ttcaatttaa tgtattgaga
    36001 aagactatat aacacaatac ctgtccaaat aaatataaac gtaattaatt gatctatact
    36061 aaaaggctct ttgaaaacaa atatgccgag tacaaacatt attgttggtc caacgtattg
    36121 aataaatcct attagcgaaa gtggaatacg ttttgccccg gctgagaata ggattagtgg
    36181 tattgccgta atagcaccag aaaataacaa ccaaaatgat gacatgttca atccaaatga
    36241 catctgatgt tgctgccata aataaataac gtatattagt ccagcaggtg ctgtaacaat
    36301 acattcaatc gtaatactgc tgatggcatc aatatgtact acttttttca ataatccata
    36361 tgtaccaaag gataacgcta atataataga aacgattggg aattctccaa tcttgagcgt
    36421 catatataat acaccgatga atgcgaataa aatggctagc cattcaaatt tattgaatct
    36481 ttcttttaaa aagataagtg cgagcaaaat gctaacaagt ggatttatat aataacctaa
    36541 acttgtttgt aggacgtgac cgttcgttac agcccaaata aatgtacccc aatttaatgt
    36601 aatgacatag cctgctacga caatcgctaa tagctgaatg ggcttgccta acaattgatt
    36661 catatctcgt tgaaatgcat tgcgttgttt ttgtccaacc gcgagtatga atatcatgaa
    36721 tattgctgaa aatataatac gaaaggctaa aatttcaaat gcgcctattg catcaacgaa
    36781 ctgccaatat ataggtagta ttccccacag aatgtatgca ctgagtgcta aaaatatacc
    36841 ttttttatat tctatattca cttacatacc tccttactct cccaaatttt taacatgtta
    36901 cgctcacttg gttatgctaa tataacgatt ttactaataa tatttcgata aagatatcat
    36961 tttgtttata tttcccacat ttattcacca accactaaac aatattaatt ttataaataa
    37021 ttctgtacaa atcagggtat attgccagaa agactaccat acaacataaa ggatggatac
    37081 aaatgacttt acctaaaatt ggaaagcctg caacacgcgc gctaaattca caaggtatat
    37141 acacattaga agcagtatca caatatacga agtcatctct aatggagatg catggcgttg
    37201 gtcctaaagc tatatcaata ttggaacaag ctttatttca gcaccaacta cattttaaaa
    37261 cggaagttca gtcatcatta ccttttaagt taacaggaga tgtgtcatgc aatcatgcgc
    37321 ctaaacgtca acaaatgata gattttatag ttgctacagc agcattagat attgaattat
    37381 tacgttcact ggttacaaca gaatttattt ggtctgtgcc tggacacttt gacatttatg
    37441 gacctcaaat tttaattcaa gaactatcta actattacaa tcaggttgct agtctcaata
    37501 tccactccaa catcacacat gggtgcttag gttccatgca tggtattgaa atattaaaaa
    37561 ctggtaaaga gattcatttt gctcattttt ttgaatttga aaatcataaa aaggatgcca
    37621 agttaagcaa agtgacatct tacattgttg ttgcttaatg actcataatc tataacgcta
    37681 aaaactatcg taattacata tatatgttaa taaaacaaat aattttgcat aatatttttg
    37741 ttatatgaat gctttttact agagtgcaca ttgaacatac agtatgatta aatatcatgt
    37801 tatgaaagaa ggatatattt tgactgtttt taaaaatgag cgcttaagct ggttaccata
    37861 catagctatt gtcattttgt tacacgttat tgggtttagt tttttatgga ttgctggaaa
    37921 agaccatcat atcttatttg gtatggggat tcttgcatac acattaggtt tgcgtcatgc
    37981 atttgatgca gatcatatcg ccgcgataga caataccgtt cgtaaattat tacaacaacg
    38041 caaagatcca tctggtgtgg gtttctattt ttcaattgga cattcatctg ttgtattttt
    38101 aatggctgtt tttttaggga tatctgtaaa atgggctaaa gatgaattac cacatttcca
    38161 agatattggt ggaacgattg gtacactagt ttcaggtttc tttttagtgc ttatcggtgt
    38221 gttgaatcta attattttaa tctctttaat taacttgttc gctaaattac gtcgtgaaca
    38281 cattgaagaa gctgaagtcg atgtattact tgaatctaga ggatttgttt ctcgatttgt
    38341 aggaccttat ttcaagttaa tcacgcgtag ttggcacgta ttgccacttg gctttttatt
    38401 tggacttggt tttgatacag ctagtgaaat tgcgttactc gctctttctt caggcgcatc
    38461 acaacaagcc atttcattta tcggaatctt atctttacca attttattcg catcaggtat
    38521 gagtttattg gatacattag atggtgttgt aatgaagtat gcctataatt gggcattctt
    38581 caatcctatt cgcaaaatct attacaatat aacgattact gcgatatcag tcatggcagc
    38641 attagtgatt gggatgattg aattgctaca aattcttgct gataagctag atttacatgg
    38701 tgcgttttgg gcattcattg gttcgatcga atttgattat ttaggctata ttttagttgc
    38761 attattttta attacttggc ttatttcaag tttaatttgg aagtttggtc gcatagaaca
    38821 caaatggtct aaataaagta acttgtcttg caactacctt tgtattgttg catttttaga
    38881 caccctgcac acttcttcca ttatgctacg ctctcagtag tcatctttaa atcgtttctt
    38941 ttagagatga cttcattttg agagcgtatt tttctattta aaatgtattt atccaaaatt
    39001 caatgctttc gaatttaaaa tttcagcatt tctgtttaaa atttaattat aatctttaat
    39061 acaggaggcg ctatgcttat gaatattgcg aagttagaga attatttaca aattgattca
    39121 tctcgttata atcgaccgag tattgaagca ttaaattatt atgcaacacg ttttatgtta
    39181 actgtacctt ttgaaaatat tgatgttcaa aatagtaagc cgatatctat aaatatcgat
    39241 gcacttttta ataaaattgt tcatgataaa cgtggtggtt tttgttatga gttaaataca
    39301 tttttcaaag catatttaca acaaaaagga tttaatcctg aattaatgtc agctactatt
    39361 cacacacccg gtggcggtcg tagtctgaac ggttcacatg cttcacttgt tgtttctata
    39421 aatgatgtat tctatgtaac tgatgttggc tttggagact tacctctaca tgccattcct
    39481 attacttcat ctgagcatac acaaccaatt actgatatca gtggtacatt ccgcgctatt
    39541 tttaacaacg aagacaagga tattttctat gttcaaaaat tcgaaaatga tcattggcat
    39601 acaaaatatg aagctgaatt caaacctaaa caaatagaag attttaatag caacatcgaa
    39661 tataatcaaa cgcatccaga ttcaatattt gtacagcatt tattaattac aatgccacaa
    39721 tcatttggcc gtgctacaat gtctgaaaat catttaactt taacaaggaa tggtagctca
    39781 gaaaaatttg atgtcactaa agataactat aaacattttt tagaaaaata ttttggacta
    39841 aatgtaacta ttaatcgtat tgaaaaacaa taatagtaaa atataaaaat atgggcgtat
    39901 cttacttatt gtaggtagcg cccctttttt atgcttcata aacacaacaa aaaggatatg
    39961 acacaaactt catgtcacac ccttcttttg aaccgcttca ttttacttaa gcaagtgcat
    40021 ctacaacata aatgacacct acgaatacaa atgcaatagc aatcatcgtc gaaataaaga
    40081 cgatacccat taatggatta aataataaaa tgacaccgaa aacaatacct aataaattaa
    40141 aaatcactga aattagtttt aagctaccac tacccgtaaa cgtaaataat cctgcaatag
    40201 aactaaaaat gaaccagaat gcaaacatgt agataaaaaa tgccgagcta gcgccaacat
    40261 taaaaatgac aataagacca aagagaatat ctacaatccc cataaacaga atccaatttt
    40321 ggttaccacc tactaaagct tttgcttttc tacggtaaat gatttgaatc acaccgttaa
    40381 ttaatacaaa cagtccaatc aaccaggtaa tagcataaaa attttcaatt ggaaatgtaa
    40441 aaataacgac tgccaacatt aataataata cacccattat taaactagac catttaatac
    40501 cttgatttcc tttttccata acaatcaatt cctttcaaat aaagccctct tttaattttt
    40561 acaaaaaatt tattatacaa taattaaatt cccttttctc aatttacaca aacatcatca
    40621 cttagaaagc accattgctt ttgtctaata tgtacgatta atctgtatcc tcactcaaaa
    40681 atctactaag tagcgatagc tttcaactct gtaaggttca ttcattgaat tgtaagttta
    40741 gataaaggct actactccaa acattattta aaatgaaatt aaatacaaaa ggagtgagac
    40801 tatgacaata ttatcagtgc aacatgtttc aaaaacatac ggtaaaaagc acacatttca
    40861 agcacttaaa gatattaact ttgacataca aaaaggcgaa ttcgttgcga ttatggggcc
    40921 ttctggatca ggtaagacaa ccttattaaa tgtactaagt tcaattgacc aaatttctag
    40981 cggtagcgtg attgctaacg gacaagagct taataaactt aatcaaaaag cacttgccaa
    41041 attccgtaaa gaatcattag gtttcatctt ccaagattac agtattctgc cgacattaac
    41101 tgtcaaagaa aacattatgt tacctttatc tgttcaaaaa atgtcgaaag caacaatgga
    41161 agaaaattat aaagcgatta ctacagcatt aggtatttat gacctaggaa ataaataccc
    41221 tagcgaatta tctggtggtc aacaacaaag aactgcagca gcgagagcat ttgttcacaa
    41281 accacaaatc atatttgcag atgagccaac aggcgcactc gactcgaaaa gtgcaaatga
    41341 cctattacaa cgtttggaag aaatgaataa atcgtttgat acaactattg tcatggttac
    41401 acatgatccg gttgcagcaa gttttgcaga acgtgtcatc atgctaaaag atggccaaat
    41461 tcatacacaa ctttatcagg aaggacgttc taaacaggcc ttttatgaag acattgtaca
    41521 tcttcaatca gtattaggtg gtgtctcaaa tgacatttaa ccatatcgtt ttcaaaaact
    41581 tacgacaaaa cttaaaacat tatgcaatgt atttattttc attatttttt agcatcgtct
    41641 tatatttcag ttttacaacc ttacagttta ctaaaggtgt aaataatgac gactcgatgg
    41701 ccatcattaa gaaaggtgct ttagtcggat caatattttt atttatcatt attgtcatct
    41761 ttttaatgta tgccaatcat ttattcgtga aacgccgtac acgtgaattt gcgctatttc
    41821 agttgattgg tttaacacga caaaacattt tgaaaatgtt agcacttgaa caaatgattg
    41881 tatttttaat cacaggtgtt gtcggtgtat tatgtggcat tgcaggtgca caattattgc
    41941 tttccatagt atctaaattg atgtcgttat cgattaactt atcgatacat ttcgaaccta
    42001 tggcccttgt tttaactatt ttcatgctaa ttattgcgta tgtactgatt ttatttcaaa
    42061 gtgctttatt tctaaaaaga cgtagtatct tatcaatgat gaaagattca attaaaactg
    42121 atgccacaac tgctaaagta acgactgcag aggttatttc aggcgtatta ggtattgcta
    42181 tgattgcact aggctattat atggcgacag aaatgtttgg aacatttaaa gcactaacta
    42241 tggctatgac atcaccgttt atcattttat ttttaacggt agtaggcgcc tatttattct
    42301 tcagaagttc cgtgtcacta atttttaaaa ctttgaaaaa atctaaaaat ggacgcgtat
    42361 ctattacaga tgttgtattt acatcgtcta ttatgtaccg aatgaagaaa aatgcgatgt
    42421 ctttaactat cattgcaatt atttctgcag ttacagtaac tgtattgtgt ttcgcggcat
    42481 tatctaaatc aaatacagat caaaccctta catctatggc accaaatgaa tttaacgtgg
    42541 tcgctactca agatgctaaa caatttgaaa ctaaactaag ccaacaacaa attacatttt
    42601 ctaaaaatgc ttacgaaact attactgtag ataatgttaa agatcaggtt attactttgg
    42661 aaaatggtag tgattcaggt cgcacgaatt caatattaag tgcaaataac aaggtaacag
    42721 gcaacaatgc catcattaca aatacaaaat cacttcctaa cattattaat atccatttaa
    42781 acaaagattt agtagtaaaa ggaactaaga atgaaacttt ccgtgttaca caagaagaca
    42841 aaggtagggt ttatccttta aatctaagct tcaactcacc tgtcgtcgaa gtaagtcctg
    42901 aaaagtatca gcagttgaaa acacaaaata acgttcatac tttttatgga tatgatatta
    42961 aacaaacatc acaaaaggaa aaagctcaag caattgcaaa acagtttgga gacaaagtca
    43021 tcacttatga tgaaatgaaa aaagaggtcg atgctactaa cggtattcta atatttgtta
    43081 catcattttt aggattagca tttttagtag cagctggatg tattatttat attaaacaaa
    43141 tggatgaaac tgaggatgaa ctaagtaact tcagaatatt aaaacgcata ggctttacgc
    43201 atacagatat gcttaaggga ttattattaa aaattacttt caacttcggt ttaccattat
    43261 tgattgctat attacatgca gtattcgccg caatagcatt tatgaaattg atgggtaata
    43321 tttccttcat gccggttatt gtagtaattg ttgtatacac cctcatttac attacttttg
    43381 ctttaattgc ttttgtacat tcaaacaaat tgattaagaa aaccatttaa cacttacgat
    43441 taaaagatgc ttcattgaga ttttgatttt aagcaatgca gtataactat taactgattt
    43501 ataaaaagga gagattgaat catgaaattt agagaattag taaaacaatc atacgaggat
    43561 ttgaaaaatt tgactgtaac ttggtataac gtgattgctt tagcaatgat tgttattgtc
    43621 ttaagcgtag ttacaacacc aattataggt attccagctg gtttattagg tggcgcttat
    43681 tatttaaaac gtcgtgaaga aaaaggtaaa taagcacatt ccatcggcat ataacattgc
    43741 tatgaccttt caagtcagat tttaatatca acaagtagca tttatcgctg cttgtttttt
    43801 atgaattgct tataaaatcg tcatgtttaa acgttatgtc actttgaaaa ctagcaaaca
    43861 ccataaaaga ctacaatttt ttatttttat aaaccccttt aaatcaacgt ttctaaggtt
    43921 tttaaaaatc tttttaaatt tattttcaaa aaacactgta cattatgcca atatgagcgt
    43981 atagttggtc ttacgtaata aaagctcgtg aattaaattg tagtgtattt gtttagaata
    44041 tcctcttttt tagttatgaa tttgttacaa atattaagtg caaaagcaca tggaggtttt
    44101 ctatatgaat aacggtacag taaaatggtt taacgcagaa aaaggttttg gtttcatcga
    44161 acaagaaaat ggcggagacg tattcgtaca tttctcaggt atcgctagcg atggctacaa
    44221 aactttagaa gaaggtcaaa aagttacttt cgaaatcact gaaggtcaac gtggagacca
    44281 agcagttaac gtacaaactg tttaatctta caaaataaaa cgactcatta taaatgaatc
    44341 gctttgatta ccaacaaggt tctaaatctt gttggtattt ttttatgcta ttttggataa
    44401 tatgagacaa tacgatgatg atttataaaa acttatttgc catatacaca ctaaggaaaa
    44461 ttatgaggct gagtatacca attgctgata taatagaaag cgcatttgtc atcgtatttc
    44521 tagctttagt cgtttgtact tcactaggat cttttccatt cataaaagca acaattcgat
    44581 cgtagttgtc cattttatgc acttttttta aatcttctat tttcatagat gcataaaaac
    44641 ctattcccaa aatgattgcc accgttatac cccaagtcca attccaataa acaactaaag
    44701 gtcccattaa aattgcagct aatgtcatga aaataagcat cacatatgtc cataagttaa
    44761 gacttcgttg cactttaata tcaggtacaa atggaatagt cccttttact aaatcatcta
    44821 aagttacatt gaacaattcg cacatcatta ataagttatg tatgtctggt aagcttttgt
    44881 cattttccca attagaaata ctctgcctag atacatataa cttttcagca agatattctt
    44941 gtgaataacc atctcgttcc ctatactttt taatttgttt actcagattc aattacatac
    45001 gcctccagtc aattagtaca atcattacaa tcagactatc agataaactt agttaaagtc
    45061 acctttatga ttgactaaat gttttgacat acgacaacat cggggttcga agactccctt
    45121 aagacagacc tgtataatta cgcgcttgta attttctcaa tgccaacttg aatttcactt
    45181 attaatgatg caacttttcc atgctattca atgcttgcaa agttagtcct agttaagaga
    45241 ttacgttcac actatttact attcgatttt ccagctttcc aactatgctt ttctaatctt
    45301 ttttgtgcta taaattctac cgcttcaaaa atacatactg cactgatgaa ccagcttagg
    45361 aaaccaacaa taatgctaat caaccacatg tgcgtcatat gtaacatcat ccatgtaact
    45421 aaaatacaaa ctaatacccc tgtcatacca aacactgcgc cacgacttac atgcacagcg
    45481 actttatcac catattgcat acctgtaata aacatagaca ctaaaaatac tgccggaaac
    45541 gttgcaaata taccgccaaa ttctttccaa ggtagtgtta cagatacaat ataacttaat
    45601 aatactgcaa atccccccac aaaaaatttc attaatgtta atttcatgat gttctgcctc
    45661 caaaaattta ttacttaata actgaataca actaattatc acgcattttc caaactataa
    45721 atgtctaata ctgaatattg cgagggaaat aacaaaccaa caaacaactg tgaatattgc
    45781 gcctttccga taacctttat gcttaatata gagagatgtc aaaaatacag ttaatataca
    45841 agacagaata ccgacaattg ctccagtact aagattcatc gacatctcca ctaattgcgt
    45901 accacgatga tctaaagcta atgcgataat agccgcaaga aagactgccg gcatagtagc
    45961 tataatacct cctaacttac cacctacctt atcagcaata attgaagcta atgcaacagc
    46021 gataccacca atgacaaaat gaagaattgc acttccaatt gaaaacatct tcaacgtacc
    46081 tttctataat taattcaata caaaacgtat cattcacaca aagtgtaaaa cttaaatttt
    46141 ctactgtaaa ggcaactcaa gcgatgttca taaagctttc atgatacttt cataaactag
    46201 caataaaggg ttcaaatgaa ggtatatcca gctcaaatta gggagtggga cagaaatgat
    46261 attttcgcaa aatttatttc gtcgtcccac cccagcaagg ttgactagaa ttgaaaaaag
    46321 cttgttacaa gcgcattttc gttcagtcaa ctactgccaa tataacttcg tagagcatag
    46381 aacattgatt tatgtaccag cctgatcaac atataaatat aaatttttat gtttcacgta
    46441 aaacaaaaaa agacaaagct gttatgatct tagctttgtc ttttatgtgt tagtcatcat
    46501 gtatacgaca tcctactact aacgtttata tattcgaatt tttatttcat aataatcttc
    46561 atgatctttg tctttatgct caacatgtag tcctgtttgt tgaatcgctt ggatactttt
    46621 gcctacctca tctcgtgctt gagtgacatc ttgtgcaaag cgaaggtttt gtgctttgac
    46681 tttttcgggc cccgtttttt ggcgtactct atcttcagtc tgtttcacat ttagtttttg
    46741 tgcaatgact tgctcaatca acgcttcttg ttcactatca gacaatgata ataccgctct
    46801 cgcatggcgt tcagtaattt taccttctct taagcgaagt agtactttcg gcgccaactt
    46861 caataaacgc aacttatttg caataaagct ttgactttta cctaaacttt ttgccaattc
    46921 actttgcgtt gtatcaccaa tttccaataa tttcttatag gcttccgctt cttcaacaac
    46981 agacaaattt tctctttgaa tattctcaat taatgcaaca acagccgtct cttcatcatc
    47041 catatcacga ataataacgt ctgcttgagg taaatttagt gattgtattg ctctaaatcg
    47101 gcgctctcca gcaataattt caaacatatc ttcttcaatc ggtcttacaa caataggttg
    47161 tagtaaacca tgttcatgta ttgattcagc aagttcttta attttatttg gttcaaacac
    47221 ctgtcttggt tgataacggt tgggaacgat acgttcaatt tgaatggatt caacattact
    47281 attgcgatct tcttcaatat gtccaatgat gtcatctttg tttttcaaac caaataattt
    47341 tgaaaaaggt tttttcatta tccattcgct ccttttatgt tagttgtaaa ggattatgca
    47401 ttatttttca agtaaaggag tcttattagg cgtccctggt tttcttgggt actttttcgg
    47461 cgtctgtctt tttttatcaa taatgaacat ctggcgctct ccagcatctt ctggcaattt
    47521 aaaggtatgt gtttctgtaa cgttaccacc taacacacta attgcaaatt ttgcttcttc
    47581 taattcttct tcaccttttg aagattttaa tgcaacaaac tgtccacctt ttttaattag
    47641 cggtaaacac aattcactca acacggataa tctagctact gctcttgcag taacaacatc
    47701 ataagactcc ctgtagacac ccttaccaaa tgtttctgct ctatcgtgta taaagctgac
    47761 atcctgtaat tgtaattctg acgctaaatg gtttaaaaat tgaatacgct tatttaatga
    47821 atcaacaatc gtcactttta actgcggaaa cattattttt aacggaatac ttggaaaacc
    47881 agctccagcg cctacatcac atatacttat aggctgatta aaatcaaaat aaaaactagg
    47941 tgcaatggaa tcataaaaat gtttcaaata tacatcgtgt tcatctgtaa tacttgtcaa
    48001 attcatcttt tcattccatt caacaagtaa acgataatat gtttgaaact gttgtttttg
    48061 agtctcagtt aattcaatat tatgttcttt taattgttct gctaaccatt ctacagtcat
    48121 tagtcactca ccctttggag tttaccttgt tctaagtaaa tcaataatat agatatgtct
    48181 gctggattta cccctgatat tctagaagct tgtgcaatat ttaaaggttt tacttctgat
    48241 aatttttctc gcgcttcagt cgccaaacta tcaatcttac tataatctaa gtcttctgga
    48301 attttcttct cttccatacg cttaactttc tcaacttgtt gtagtgattt attgatataa
    48361 ccttcatatt ttgtttgtat ttctacttgt tcttcaacat ctgcattcaa ttgatgttct
    48421 tcttctaaaa tttctaaaat tatatcgtaa gtcatttcag gtctgcgtaa taaatcgata
    48481 gctaaaatac catcttttaa gcgagaacca ccatgttgtt cgataatcgc ttgcgtatgt
    48541 tcgtttggtt taatacgaat atctgataaa cgcttaattt ccgcatcaat ttgctgacgt
    48601 ttttcattaa aacgtgcata tcgttcttca gaaatcatac caagttcata tcccatatcc
    48661 gtcaatctca aatcagcatt atcatgacgt agtaacaaac gatattctgc acgtgatgtt
    48721 agtaaacgat aaggttcatt agtaccttta gttacaagat catcgattaa gacaccaata
    48781 tatgcatctg aacgacttaa tatcttttcg cctgtgttta acactttacc tgcagcgtta
    48841 atacctgcca tcaatccttg tcctgctgct tcttcataac cagatgtacc attaatttga
    48901 cctgcagtat ataagttttt aatcattttc gtttcaagtg taggccataa ctgcgttggc
    48961 acaatcgcat catattcaat tgcgtagccg gcacgcatca tatctgcttt ttcaagacct
    49021 ggtatcgtct ctaacatttg acgttgcaca tgttcaggaa gacttgtaga caatccttgc
    49081 acatatactt catttgtatt acgaccttca ggctctaaga aaagttgatg tcgcggctta
    49141 tcattaaatc gaacaaattt atcttcaatt gaagggcaat aacgtggccc ggttccttta
    49201 atcatccctg aatacattgc agatagatgt aaattatcat cgataacttt gtgtgtttca
    49261 gcattagtat acgttagcca acatggcaat tgatctaata tatattctgt tgtttcaaag
    49321 ctgaatgcac gacctacatc gtcacctggt tgtatttcag tcttcgaata gtcaattgtt
    49381 tttgaattta cacgcggtgg tgtacctgtt ttaaaacgaa caatatcaaa accaagttct
    49441 cttaaattgt ctgataatgt gattgatggt aattggtgat ttggtccact tgaatacttc
    49501 atattaccta aaatgatttc accacgtaaa aatgttcccg ttgtaataat tactgcttta
    49561 gataaatact ctgtaccaat atttgtacgt acacctttaa cttcattatc ttctataata
    49621 agttcgtcta ccataccttg cattatatgc aaattttctt catcttcaat cacgcgtttc
    49681 atttcttgtt gataaagtac tttatctgct tgcgctctta gtgctcttac agcaggtcct
    49741 ttacctgtat ttaacattct catttgaatg tgtgttttat cgattgtttt tgccatttgt
    49801 ccacctaaag catcaatttc acgaacaacg atgcctttag ctggtccacc tacagatggg
    49861 ttacatggca taaatgcaat attatctaaa tttattgtta gcattaatgt tttagcacca
    49921 cgtcttgcag atgctaaacc tgcttctaca cctgcatgtc ccgcacctat aacgattaca
    49981 tcatattctt gaaccacaat ataaacctcc ttatttgata tcttactagc cttcttaaga
    50041 cgatattccg tctatttcaa ttactattta cctaagcaga attgactgaa taactgatcg
    50101 atgagttcat cacttgcagt ctcaccaata atttctccta atatttccca agttctagtt
    50161 aaatcaattt gtaccatatc cataggcaca ccagattctg ctgcatcaat cgcatcttgt
    50221 atcgtttgtc ttgcttgttt taataatgaa atatgtcttg aattagaaac ataagtcata
    50281 tcttgatttt gtacttctcc accaaagaac aaatctcgaa tttgtatttc taattcatca
    50341 ataccttctt gttttaacat tgaagtttga attaatggcg tatcacctat catatcttta
    50401 acttcattaa tatctatgtt ttgctctaaa tccattttat taacaattac gattacatct
    50461 tcatttttaa ccacttcata taatgtgtaa tcttcttgag tcaatgcttc gttattgttt
    50521 aatacaaata aaattaagtc tgcttggcta agagcctttc tagagcgttc aacaccaatc
    50581 ttctctacta tatcttctgt ctcgcgtata ccagcagtat caactaatct taatggcacg
    50641 ccacgaacat tgacgtactc ttctaagaca tctcttgtag tacctgctac ctcagttaca
    50701 atcgctttat tatcttgtat taaattattt aacatcgatg atttacctac gtttggttta
    50761 ccaacaataa ctgtagataa accttcacgc ataattttgc cctgcgcacc ggtatctaat
    50821 aaacgattaa attcctgttt gatttcttta gactgctcta aaagaaattc agtagtcgca
    50881 tcttcaacat catcgtattc aggataatca atattcactt ccacttgagc gagtatctct
    50941 aatatagatt gacgttgttt tttgattaag tcacttagac gaccttcaat ttgattcatc
    51001 gcaactttag aagctctatc tgtcttcgag cgaataaagt ccataactgc ttcagcttga
    51061 gataaatcaa tacgaccatt taaaaaggca cgttttgtaa attcacctgg ctcagccatt
    51121 ctagcgccat atgtcatagt aagttccagc actctattaa tcgttaaaat accaccatga
    51181 caattaattt ctataatatc ttcgcgtgta aatgtttttg gcgctcttaa cacagacacc
    51241 ataacttctt caaccacttc tttagactct ggatcaataa tatgaccgta attaatcgta
    51301 tgtgatggaa catcatttaa aagatgtttt cctttatata atttgtcagc aatttcaacg
    51361 gcttgcggtc cagacaatcg aacaattcca attgcccctt cacccattgg tgttgaaata
    51421 ctcgtaattg tatctaaatc catattgcta ctcgcctcct tcaacgatgt gaatacattt
    51481 taaagtaagt tattataacc ctaaggtcag tcttaaccct aaggtcagtc ttacgtttgt
    51541 ctgaggtaag acttcgggat gcgttgagtg gttaatgttt tccttcccct accctatcct
    51601 tacttaatct ttttattaaa aactttggca attttaagta cgtgctcaag actattctgt
    51661 atttgtaaag tcgtcatatc tttagctggc tgtcttgcta ttacaataat atctttggcc
    51721 aatatatgcg acttatgtac tttgaaattt tcacgtattg ctcttttaat cttgtttctt
    51781 aacactgcat tacctagttt tttagaaaca ctaataccta agcgaaaatg gtctatttct
    51841 ttattattac aagtgtatac aacaaattgt ctgttggcta cagaatgacc ttttttatat
    51901 attctctgaa aatctgcatt ctttttaatt cggtaagctt tttccaataa catcactcgc
    51961 ttatttatcg tttttatttg aagctatatt taaacttcta ttgagcttat aacataaatt
    52021 tctatttatt cttaatttaa acgaaaaaaa agatcactga tgagtcagtg atcttatgca
    52081 gataaaactt tacggccttt acgacgacgg cgcgctaaaa ctttacggcc attttttgtg
    52141 ctcatgcgtt ttctgaaacc atgaacttta ctatgtttac gtttatttgg ttgataagta
    52201 cgttttacca tgcaaaacac ctccatcttt atacagttat ctaatatacc agattatgca
    52261 gactctgatc actttaatag ataagatttt gcgtttctta gattaaaatt ctcgtattag
    52321 ctcattgatt atctagtcat aattcaagca actactacaa tataacaaaa tcctttttat
    52381 aacgcaagtt cattttatac tactgctcaa tttttttact tttatcgatt aaagatagaa
    52441 atacacgatg cgagcaatca aatttcataa catcaccatg agtttggtcc gaagcatgag
    52501 tgtttacaat gtttgaatac cttatacagt tcttatacat actttataaa ttatttccca
    52561 agctgttttg atacactcac taacagatat tctatagaag gaaaagttat ccacttatgc
    52621 acatttatag ttttcagaat tgtggataat tagaaattac acacaaagtt atactatttt
    52681 tagcaacata ttcacaggta tttgacatat agagaactga aaaagtataa ttgtgtggat
    52741 aagtcgtcca actcatgatt ttataaggat ttatttattg atatttacat aaaaatactg
    52801 tgcataacta ataagcagga taaagttatc caccgattgt tattaacttg tggataatta
    52861 ttaacatggt gtgtttagaa gttatccacg gctgttattt ttgtgtataa cttaaaaatt
    52921 taagaaagat ggagtaaatt tatgtcggaa aaagaaattt gggaaaaagt gcttgaaatt
    52981 gctcaagaaa aattatcagc tgtaagttac tcaactttcc taaaagatac tgagctttac
    53041 acgattaaag atggtgaagc tatcgtatta tcgagtattc cttttaatgc aaattggtta
    53101 aatcaacaat atgctgaaat tatccaagca atcttatttg atgttgtaga ctatgaagtt
    53161 aaacctcact ttattactac tgaagaatta gcaaattata gtaataatga aactgctact
    53221 ccaaaagaaa caacaaaacc ttctactgaa acaactgagg ataatcatgt gcttggtaga
    53281 gagcaattca atgcccataa cacatttgac acttttgtaa tcggacctgg taaccgcttt
    53341 ccacatgcag caagtttagc tgtagccgaa gcaccagcca aagcgtacaa tccattattt
    53401 atctatggag gggttggttt aggaaaaacc catttaatgc atgccattgg tcatcatgtt
    53461 ttagataata atccagatgc caaagtgatt tacacatcaa gtgaaaaatt cacaaatgaa
    53521 tttattaaat caattcgtga taacgaaggt gaagctttca gagaaagata tcgtaatatc
    53581 gacgtcttat taatcgatga tattcagttc atacaaaata aagtacaaac acaagaagaa
    53641 tttttctata cttttaatga attgcatcag aataacaagc aaatagttat ttcgagtgat
    53701 cgaccaccaa aggaaattgc acaattagaa gaccgattac gttcacgctt tgaatggggg
    53761 ctaattgttg atattacgcc accagattat gaaactcgaa tggcaatttt gcagaagaaa
    53821 attgaagaag aaaaattaga tattccacca gaagctttaa attatatagc aaatcaaatt
    53881 caatctaata ttcgtgaatt agaaggtgca ttaacacgtt tacttgcata ttcacaatta
    53941 ttaggaaaac caattacaac tgaattaact gctgaagctt taaaagatat cattcaagca
    54001 ccaaaatcta aaaagattac catccaagat attcaaaaaa ttgtaggcca gtactataat
    54061 gttaggattg aagatttcag tgcaaaaaaa cgtacaaagt caattgcata tccgcgtcaa
    54121 atagctatgt acttgtctag agagcttaca gatttctcat tacctaaaat tggtgaagaa
    54181 tttggtgggc gtgatcatac gaccgtcatt catgctcatg aaaaaatatc taaagattta
    54241 aaagaagatc ctatttttaa acaagaagta gagaatcttg aaaaagaaat aagaaatgta
    54301 taagtaggaa actttgggaa atgtaatctg ttatataaca gcactaataa taactgtcat
    54361 tttttacatt tctatatact aatgtgacaa gatgagcaaa actcattttg tggataatgt
    54421 ttaaaagtca tacacaccat acacaagtta tcaacatgtg tataacttcg ccaaatctat
    54481 gtttttacga cttatccacc aatccacagc acctactact attactaaga acttaaaacc
    54541 tatataatta tatataaacg actggaagga gttttaatta atgatggaat tcactattaa
    54601 aagagattat tttattacac aattaaatga cacattaaaa gctatttcac caagaacaac
    54661 attacctata ttaactggta tcaaaatcga tgcgaaagaa catgaagtta tactaactgg
    54721 ttcagactct gaaatttcaa tagaaatcac tattcctaaa actgtagatg gcgaagatat
    54781 tgtcaatatt tcagaaacag gctcagtagt acttcctgga cgattctttg ttgatattat
    54841 aaaaaaatta cctggtaaag atgttaaatt atctacaaat gaacaattcc agacattaat
    54901 tacatcaggt cattctgaat ttaatttaag tggcttagat ccagatcaat atcctttatt
    54961 acctcaagtt tctagagatg acgcaattca attgtcggta aaagtgctta aaaacgtgat
    55021 tgcacaaacg aattttgcag tgtccacctc agaaacacgc ccagtactaa ctggtgtgaa
    55081 ctggcttata caagaaaatg aattaatatg cacagcgact gactcacacc gcttggctgt
    55141 aagaaagttg cagttagaag atgtttctga aaacaaaaat gtcatcattc caggtaaggc
    55201 tttagctgaa ttaaataaaa ttatgtctga caatgaagaa gacattgata tcttctttgc
    55261 ttcaaaccaa gttttattta aagttggaaa tgtgaacttt atttctcgat tattagaagg
    55321 acattatcct gatacaacac gtttattccc tgaaaactat gaaattaaat taagtataga
    55381 caatggggag ttttatcatg cgattgatcg tgcctcttta ttagcacgtg aaggtggtaa
    55441 taacgttatt aaattaagta caggtgatga cgttgttgaa ttatcttcta catcaccaga
    55501 aattggtact gtaaaagaag aagttgatgc aaacgatgtt gaaggtggta gcctgaaaat
    55561 ttcattcaac tctaaatata tgatggatgc tttaaaagca atcgataatg atgaggttga
    55621 agttgaattc ttcggtacaa tgaaaccatt tattctaaaa ccaaaaggtg acgactcggt
    55681 aacgcaatta attttaccaa tcagaactta ctaaaaataa atataaataa aggatgacgt
    55741 gattaattaa aacgtcatcc tttatttttt ggcaaaaata attctagatg cgtatgtaaa
    55801 ataaatttga cagcatttta aacagcaaat aaaagacgcc aattaaattt atgacaaatg
    55861 tatccaaaat ttaataagtg tgcttatatg ccctttaaat ttaaaatttt aatagtcaat
    55921 aacaagttga atattaaagt taaacgccgt taaatagcgt taaaaaattg aaaatgacag
    55981 tattgccaaa aaataagaat taattattta tatgtaaacg gtttctacct ctattttaaa
    56041 tgaaatttgt gacaaaaaaa ggtataatat attaatgaca cacaaagaaa tggagtgatt
    56101 attttggttc aagaagttgt agtagaagga gacattaatt taggtcaatt tctaaaaaca
    56161 gaagggatta ttgaatctgg tggtcaagca aaatggttct tgcaagacgt tgaagtatta
    56221 attaatggag tgcgtgaaac acgtcgcggt aaaaagttag aacatcaaga tcgtatagat
    56281 atcccagaat tacctgaaga tgctggttct ttcttaatca ttcatcaagg tgaacaatga
    56341 agttaaatac actccaatta gaaaattatc gtaactatga tgaggttacg ttgaaatgtc
    56401 atcctgacgt gaatatcctc attggagaaa atgcacaagg aaagacaaat ttacttgaat
    56461 caatttatac cttagcttta gcaaaaagtc atagaacgag taatgataag gaactcatac
    56521 gttttaatgc tgattatgct aaaatagaag gtgagcttag ttatagacac ggcacgatgc
    56581 cattaacaat gtttataact aaaaaaggta aacaagtcaa agtgaatcac ttagagcaaa
    56641 gtcgtctaac tcaatatatt ggacacctca atgtggttct atttgcgcca gaagatttga
    56701 atattgtaaa aggctctcct caaataagac gacgctttat agatatggag ttgggccaaa
    56761 tttctgctgt ttacttaaat gatttagctc aataccaacg tattttaaag caaaagaata
    56821 attacttaaa gcagttacaa ttaggccaaa aaaaggactt aacaatgttg gaagtattaa
    56881 atcagcagtt tgctgaatat gcaatgaaag taactgataa acgtgcacat tttattcaag
    56941 agctagagtc gttagctaaa ccgattcatg ctggtatcac aaatgataaa gaagcgttgt
    57001 cgctaaatta tttacctagt cttaaatttg attatgctca aaatgaagcg gcacgacttg
    57061 aagaaattat gtctattctt agcgataata tgcaaagaga aaaagaacga ggcattagct
    57121 tattcggacc acatcgagat gatataagtt ttgatgtgaa tggcatggat gctcaaacat
    57181 atggttctca aggacagcaa cgtacaacgg ctttgtccat taaattagct gaaattgagt
    57241 taatgaatat cgaagttggg gaatatccca tcttattatt agacgatgta ctcagtgaat
    57301 tagatgattc gcgtcaaacg catttattaa gtacgattca gcataaagta caaacatttg
    57361 tcactacgac atctgtagat ggtattgatc atgaaatcat gaataacgct aaattgtatc
    57421 gtattaatca aggtgaaatt ataaagtaac agaaagcgat ggtgactgca ttgtcagatg
    57481 taaacaacac ggataattat ggtgctgggc aaatacaagt attagaaggt ttagaagcag
    57541 tacgtaaaag accaggtatg tatataggat cgacttcaga gagaggtttg caccatttag
    57601 tgtgggaaat tgtcgataat agtatcgatg aagcattagc tggttatgca aataaaattg
    57661 aagttgttat tgaaaaagat aactggatta aagtaacgga taacggacgt ggtatcccag
    57721 ttgatattca agaaaaaatg ggacgtccag ctgtcgaagt tattttaact gttttacatg
    57781 ctggtggtaa attcggcggt ggcggataca aagtatctgg tggtttacat ggtgttggtt
    57841 catcagttgt aaacgcattg tcacaagact tagaagtata tgtacacaga aatgagacta
    57901 tatatcatca agcatataaa aaaggtgtac ctcaatttga cttaaaagaa gttggcacaa
    57961 ctgataagac aggtactgtc attcgtttta aagcagatgg agaaatcttc acagagacaa
    58021 ctgtatacaa ctatgaaaca ttacagcagc gtattagaga gcttgctttc ttaaacaaag
    58081 gaattcaaat cacattaaga gatgaacgtg atgaagaaaa cgttagagaa gactcctatc
    58141 actatgaggg cggtattaaa tcgtacgttg agttattgaa cgaaaataaa gaacctattc
    58201 atgatgagcc aatttatatt catcaatcta aagatgatat tgaagtagaa attgcgattc
    58261 aatataactc aggatatgcc acaaatcttt taacttacgc aaataacatt catacgtatg
    58321 aaggtggtac gcatgaagac ggattcaaac gtgcattaac gcgtgtctta aatagttatg
    58381 gtttaagtag caagattatg aaagaagaaa aagatagact ttctggtgaa gatacacgtg
    58441 aaggtatgac agcaattata tctatcaaac atggtgatcc tcaattcgaa ggtcaaacga
    58501 agacaaaatt aggtaattct gaagtgcgtc aagttgtaga taaattattc tcagagcact
    58561 ttgaacgatt tttatatgaa aatccacaag tcgcacgtac agtggttgaa aaaggtatta
    58621 tggcggcacg tgcacgtgtt gctgcgaaaa aagcgcgtga agtaacacgt cgtaaatcag
    58681 cgttagatgt agcaagtctt ccaggtaaat tagccgattg ctctagtaaa agtcctgaag
    58741 aatgtgagat tttcttagtc gaaggggact ctgccggggg gtctacaaaa tctggtcgtg
    58801 actctagaac gcaggcgatt ttaccattac gaggtaagat attaaatgtt gaaaaagcac
    58861 gattagatag aattttgaat aacaatgaaa ttcgtcaaat gatcacagca tttggtacag
    58921 gaatcggtgg cgactttgat ctagcgaaag caagatatca caaaatcgtc attatgactg
    58981 atgccgatgt ggatggagcg catattagaa cattgttatt aacattcttc tatcgattta
    59041 tgagaccgtt aattgaagca ggctatgtgt atattgcaca gccaccgttg tataaactga
    59101 cacaaggtaa acaaaagtat tatgtataca atgataggga acttgataaa cttaaatctg
    59161 aattgaatcc aacaccaaaa tggtctattg cacgatacaa aggtcttgga gaaatgaatg
    59221 cagatcaatt atgggaaaca acaatgaacc ctgagcaccg cgctctttta caagtaaaac
    59281 ttgaagatgc gattgaagcg gaccaaacat ttgaaatgtt aatgggtgac gttgtagaaa
    59341 accgtagaca atttatagaa gataatgcag tttatgcaaa cttagacttc taagcgctgt
    59401 gaactgaact tttgaaggag gaactcttga tggctgaatt acctcaatca agaataaatg
    59461 aacgaaatat taccagtgaa atgcgtgaat catttttaga ttatgcgatg agtgttatcg
    59521 ttgctcgtgc attgccagat gttcgtgacg gtttaaaacc agtacatcgt cgtatactat
    59581 atggattaaa tgaacaaggt atgacaccgg ataaatcata taaaaaatca gcacgtatcg
    59641 ttggtgacgt aatgggtaaa tatcaccctc atggtgactt atctatttat gaagcaatgg
    59701 tacgtatggc tcaagatttc agttatcgtt atccgcttgt tgatggccaa ggtaactttg
    59761 gttcaatgga tggagatggc gcagcagcaa tgcgttatac tgaagcgcgt atgactaaaa
    59821 tcacacttga actgttacgt gatattaata aagatacaat agattttatc gataactatg
    59881 atggtaatga aagagagccg tcagtcttac ctgctcgatt ccctaacttg ttagccaatg
    59941 gagcatcagg tatagcggta ggtatggcaa cgaatattcc accacataac ttaacagaat
    60001 taatcaatgg tgtacttagc ttaagtaaga accctgatat ttcaattgct gagttaatgg
    60061 aggatattga aggtcctgat ttcccaactg ctggacttat tttaggtaag agtggtatta
    60121 gacgtgcata tgaaacaggt cgtggttcaa ttcaaatgcg ttctcgtgca gttattgaag
    60181 aacgtggagg cggacgtcaa cgtattgttg tcactgaaat tcctttccaa gtgaataagg
    60241 ctcgtatgat tgaaaaaatt gcagagctcg ttcgtgacaa gaaaattgac ggtatcactg
    60301 atttacgtga tgaaacaagt ttacgtactg gtgtgcgtgt cgttattgat gtgcgtaagg
    60361 atgcaaatgc tagtgtcatt ttaaataact tatacaaaca aacacctctt caaacatcat
    60421 ttggtgtgaa tatgattgca cttgtaaatg gtagaccgaa gcttattaat ttaaaagaag
    60481 cgttggtaca ttatttagag catcaaaaga cagttgttag aagacgtacg caatacaact
    60541 tacgtaaagc taaagatcgt gcccacattt tagaaggatt acgtatcgca cttgaccata
    60601 tcgatgaaat tatttcaacg attcgtgagt cagatacaga taaagttgca atggaaagct
    60661 tgcaacaacg cttcaaactt tctgaaaaac aagctcaagc tattttagac atgcgtttaa
    60721 gacgtctaac aggtttagag agagacaaaa ttgaagctga atataatgag ttattaaatt
    60781 atattagtga attagaaaca atcttagctg atgaagaagt attactacaa ttagttagag
    60841 atgaattaac agaaattcga gatcgtttcg gtgatgatcg tcgtactgaa atccaattag
    60901 gtggatttga agatttagaa gatgaagatc tcattccaga agaacaaatt gtaattacac
    60961 taagccataa taactacatt aaacgtttgc cggtatctac atatcgtgct caaaaccgtg
    61021 gtggtcgtgg tgttcaaggt atgaatacat tggaagaaga ttttgtcagt caattggtaa
    61081 ctttaagtac acatgaccat gtattgttct ttactaacaa aggtcgtgta tacaaactta
    61141 aaggttatga agtgcctgag ttatcaagac agtctaaagg tattcctgta gtgaatgcta
    61201 ttgaacttga aaatgatgaa gtcattagta caatgattgc tgttaaagac cttgaaagtg
    61261 aagacaactt cttagtgttt gcaactaaac gtggtgtcgt taaacgttca gcattaagta
    61321 acttctcaag aataaataga aatggtaaga ttgcgatttc gttcagagaa gatgatgagt
    61381 taattgcagt tcgcttaaca agtggtcaag aagatatctt gattggtaca tcacatgcat
    61441 cattaattcg attccctgaa tcaacattac gtcctttagg ccgtacagca acgggtgtga
    61501 aaggtattac acttcgtgaa ggtgacgaag ttgtagggct tgatgtagct catgcaaaca
    61561 gtgttgatga agtattagta gttactgaaa atggttatgg taaacgtacg ccagttaatg
    61621 actatcgttt atcaaatcgt ggtggtaaag gtattaaaac agctacgatt actgagcgta
    61681 atggtaatgt tgtatgtatc actacagtaa ctggtgaaga agatttaatg attgttacta
    61741 atgcaggtgt cattattcga ctagatgttg cagatatttc tcaaaatggt cgtgcagcac
    61801 aaggtgttcg cttaattcgc ttaggtgatg atcaatttgt ttcaacggtt gctaaagtaa
    61861 aagaagatgc agaagatgaa acgaatgaag atgagcaatc tacttcaact gtatctgaag
    61921 atggtactga acaacaacgt gaagcggttg taaatgatga aacaccagga aatgcaattc
    61981 atactgaagt gattgattca gaagaaaatg atgaagatgg acgtattgaa gtaagacaag
    62041 atttcatgga tcgtgttgaa gaagatatac aacaatcatc agatgaagat gaagaataat
    62101 aaaaaaataa gacttcccta tatgtagggg agtcttattt ttatgctaga aagtaatgct
    62161 gtactatatt caatgattag taatgattaa ctttctaatt gtttcattgc gtaaggtatt
    62221 tcattgataa gtcttgatgg tggtaccaca tacatatctt ttgcaaggtt ttcgccaata
    62281 aaactatgtg tatatgtggc actcataacc gcttctttta agttatcaaa ttgaccgaca
    62341 aaacttgtaa tcataccagc aagtgtatcg cccataccac cagtcgccat tgctgggcta
    62401 ccgattgtta atttaaagtc ttcatcttta aagaaaattt cagtaccatg ttttttaagt
    62461 acaacagttg cacctaaacg atcaactgct tcacgattac gctcatatgt ctgttcctca
    62521 ataggaatac cacttaatcg ttcccattct ttgaggtgtg gagtaaagat cacacgacat
    62581 gtaggtaatt gcggtttcag tttactaaag attgtaatcg catcgccgtc tacgattaaa
    62641 ttttgatgcg gttgtatatt ttgtagtagg aatgtaatgg cattatttcc tttgaaatca
    62701 acgccaagac ctggaccaat tagtatactg tcagtcattt caatcatttt cgtcaacatt
    62761 ttcgtatcat taatatcaat aaccatcgct tctgggcaac gagaatgtaa tgctgaatga
    62821 tttgttggat gtgtagctac agtgattaaa ccactaccgc taaatacaca tgcacgagcc
    62881 gctaacataa tggcaccacc taagttagca gatccaccaa ttaataaaat tttgccataa
    62941 tcacctttat gtgaatcttc tttacgctta ggaatgttaa tagaatttaa cgtttccata
    63001 gtgatataac ctcccatgta aaagcctttt ccaaatttat tcaattttaa aaatatatag
    63061 taaattttaa caaaatgtat tataaatttc tgaattcatt attatttgtc gttaaataca
    63121 atagaaaata ctatacctgt atatgcaatt cgtcaataga taaattatta aatatgctta
    63181 caacaatctt aatatccttt aacgcactac aatagtgctc tgataatagg ttataaatgt
    63241 acgtaaaacc attgtttcaa taaaaatgaa aacgtatact tcaagaagga tgggttactt
    63301 aatataaaca agggggtaac atatatgact ttatatttag atggtgaaac actaacaatt
    63361 gaggatatta aatcattttt acaacaacaa tcaaagattg aaattattga tgatgcgtta
    63421 gaacgtgtca aaaaaagtag agcggtagtt gaacgtatta ttgaaaatga ggaaacggtt
    63481 tacggtatca ctacaggttt tgggttattt agtgatgtac gtatagaccc gacgcaatat
    63541 aatgaattac aagtgaatct gatacgctca catgcctgtg gactaggtga gccattttca
    63601 aaagaagtag cattagtcat gatgatttta cgattgaata cattattaaa aggtcattca
    63661 ggtgccactt tagaattagt gagacaatta caatttttta taaatgaacg tattataccg
    63721 ataatcccac aacaaggctc tctcggtgca tcaggagatt tagcgccatt atcacattta
    63781 gcattagcat taattggtga agggaaagta ttgtacagag gggaagaaaa ggatagtgac
    63841 gatgtattaa gagaattaaa tagacaacct ttgaaccttc aggctaaaga gggtttagca
    63901 ttgattaatg gtacgcaagc tatgacagct caaggtgtca ttagttatat agaagcagaa
    63961 gatttaggtt accaatctga atggattgct gcattaacgc atcagtctct taatggcatt
    64021 atagatgcat atcgacatga tgtgcactct gttcgtaatt ttcaagaaca gattaatgtg
    64081 gcagcgcgta tgcgtgattg gttagaagga tcaacattaa cgacgcgaca agcagaaata
    64141 cgtgtacaag atgcatatac gttgcgttgt ataccacaaa tccatggcgc gagttttcaa
    64201 gtattcaatt atgttaaaca gcaattagaa tttgaaatga atgcggctaa tgataatcca
    64261 cttatatttg aggaagcaaa tgaaacgttt gttatttcag gtggtaactt ccatggacaa
    64321 cctattgctt ttgcattaga tcatcttaaa ttaggtgtaa gtgaattagc aaacgtatcg
    64381 gaacgtcgtc tagagcgact agtaaatcct caattaaatg gtgatttacc agcatttctt
    64441 agtccagagc caggattgca aagtggcgcg atgattatgc aatatgctgc tgcaagtctc
    64501 gtttctgaaa ataaaacttt agcgcatcca gcgagtgttg attctatcac ttcatctgcg
    64561 aaccaagaag atcacgtatc tatgggaact acagctgcta gacatggtta tcaaattatt
    64621 gaaaatgcaa gacgtgtgtt ggcaatcgaa tgtgttattg cattacaagc agcagagttg
    64681 aaaggtgtcg aaggattatc accaaaaaca cgtcgtaaat atgaggagtt tcgaagtatc
    64741 gtgccatcca ttacacatga ccgtcaattt cataaagata ttgaagcggt tgcacagtat
    64801 ttaaagcaat caatttatca aacgactgca tgtcactaaa tcgacatgag tgatgtttga
    64861 aatcgttact tgaaaaagca aatatagttt gctatattaa aattaactta ataagacatt
    64921 gttcgtagga caagtaatat atagtgttcg atatcagaga gcttgtggtt agtgtgaaca
    64981 agaatcaaca tatatatgaa tctacctact taatttaaaa gaacaatcgg tgataaccgt
    65041 tattttagtg aagtgcaatt taggtttagt gtatctttat aacttaaatt gttaaatagg
    65101 gtggcaacgc gtagaccacg tcccttgtag ggatgtggtc tttttttatt ttctaaaaaa
    65161 taaagacgta cgtcattcca taataaatga taattatttg ggaaaggatg aaggttaatg
    65221 ttagacatta gattattcag aaatgagcct gacacagtta agagcaaaat tgaattacgt
    65281 ggagatgatc caaaagttgt agatgaaatt ttagaattgg atgagcaacg acgtaaatta
    65341 attagtgcaa cagaagaaat gaaagcacgt cgtaataaag taagcgaaga aatcgcatta
    65401 aaaaaacgta ataaagaaaa tgctgatgat gtgattgctg aaatgcgcac attaggtgac
    65461 gatattaaag aaaaagatag tcaattaaat gaaattgata ataaaatgac aggtatcctt
    65521 tgtcgtattc caaatttaat aagtgatgat gtacctcaag gtgaatctga tgaagataac
    65581 gttgaagtta aaaagtgggg tacaccacgt gagttttcat ttgaaccaaa agcacattgg
    65641 gatattgtag aagaattgaa aatggctgat tttgatcgtg cagcaaaagt ttcaggtgcg
    65701 cgttttgtat atttaacaaa tgaaggtgcg caattagagc gtgctttaat gaactatatg
    65761 attacaaaac atacaacaca acatggttat acagaaatga tggtaccaca gcttgtgaac
    65821 gcagatacaa tgtatggtac aggtcaatta cctaaatttg aagaagattt atttaaagta
    65881 gaaaaagaag gattatatac aattccaact gctgaagtac cattaacgaa tttctaccgt
    65941 aatgaaatta ttcaaccagg tgtacttcct gaaaaattca ctggtcaatc tgcatgtttc
    66001 cgtagtgaag caggatcagc aggtagagat acaagaggat taattcgttt acatcaattc
    66061 gataaagtgg aaatggtacg ttttgaacaa cctgaagatt catggaatgc tttagaagaa
    66121 atgacaacaa atgcagaagc aattctagaa gagttaggtt taccataccg tcgtgttatt
    66181 ttatgtacag gtgatattgg atttagtgca agcaaaacat atgatataga agtttggtta
    66241 ccaagctaca atgattataa agaaattagt tcatgctcaa actgtacgga tttccaagcg
    66301 cgtcgtgcta acatccgctt caagcgtgac aaagcagcta aaccagaatt agcacataca
    66361 ttaaatggta gtggtttagc agttggacgt acatttgctg ctattgttga aaattaccaa
    66421 aatgaagatg gaacagtaac aattccagaa gcattagtac catttatggg tggtaaaaca
    66481 caaatttcaa aaccagttaa ataaaggctt tagctacaag ctttaaaaag tatatattct
    66541 acgtatactt aaagcaaggg caagatactt taaataatat tttaaaaagt ggtgacgaag
    66601 ctgtcgccac tttttttgtg ctgtaaaagt ataatagtga gccaatgcac ataacaacaa
    66661 taaattaagt ttgtggttta atggggtgaa cgcatttcat tatagcaaca atacgggata
    66721 attatgatga actaaaacaa tctaaaacgt aacaattttg agcatcacta ttataggaaa
    66781 ttaagtgata aaaaactgat ttcgttgatg tagtatgagt aatatcgatg gagtagggta
    66841 gggggagagg atgatgatta taagggagtg ttacatgaat caatatccca gactcatcat
    66901 tagatataaa aaattataaa attagtactt aaaaacaact acaaatccgt agaaaatatg
    66961 gaggtagtct taaataaaaa ttgaaaatta tcaaaaataa aaagttgata tgaagatgat
    67021 tgaagacgcc agtatgtcta acctcagaca aactggtgtc taatgttatt gcttagggta
    67081 tagaactgta ttagactagg tatattattt tttcgtaatt atataaatat aaagtggcaa
    67141 aggaggtaat tgagatggca acacatttaa gttttagaca aggcgtacaa gagtgtatcc
    67201 caacattatt gggttatgcc ggtgttggta tttcatttgg tattgtggct tcgtctcaaa
    67261 actttagtat tttagaaatt atcttgttat gtcttgttat atatgccggt gctgcgcaat
    67321 ttattatgtg cgcgttgttt atagcaggta caccgatatc agcgattgta ctaactgtat
    67381 ttatcgtaaa ttcaagaatg ttccttttaa gtatgtcgct tgcaccaaac ttcaagacat
    67441 atgggttttg gaaccgtgtt ggattaggtt cattagtaac tgacgaaacg tttggcgtcg
    67501 ccattacacc ttatttaaaa ggagaagcta tcaatgatcg ttggatgcat ggtcttaata
    67561 tcacagcata tttattttgg gcaatttcat gtgtagctgg ggctttattt ggcgaatata
    67621 tctcaaatcc gcaaacgcta gggttagatt ttgctatcac ggctatgttt atctttttgg
    67681 ccattgcgca atttgaatca attactaaat cgcgattaag aatttacata gtactcatta
    67741 ttgccgtcat agtaatgatg ttatcgctaa gtatgtttat gccttcatat ctagcaatat
    67801 taattgcagc cacaatttca gcagcgttag gagtgatgat ggaacgatga taactcatat
    67861 gaacatgtta atacttattt tattgtgtgg tatcgtaacg ctattaattc gaattatacc
    67921 ttttatcatg atttcaaaag tgcaattgcc tgatgttgtg gttcgatggc tatcatttat
    67981 cccaatcaca ctatttacgg cacttgtcat tgacagcatt attcaacaga cgcctcatgg
    68041 tgaggggtat acattaaaca tcccttacat tatcgcgctc attccgacgg ttattttatc
    68101 tataatcacg cgtagtttaa ctattacaat tattagtggg attgttatca tggcaacatt
    68161 acgatttttc ttttaaaaat aactgaaaat cattgaacag atatttaaac ttaggtaaac
    68221 tgttagtaat cagaaaattc tgatatacaa atcgtctatg gtatgactgg gaatcgtata
    68281 cacgaaagcg atttggctaa cgtatgacaa tgataacaat attttaaatg ataaaagtaa
    68341 ttcatcactg aatctcaact aacacataac aatttcatat ttcttattgt gagaagttga
    68401 gggacttggc cctgtgatac ttcagcaacc gactttatag cacggtgcta aaaccaacga
    68461 gttactcgaa tgataagtat aaagacttct tacttttcaa tagggtgaga agtttttttg
    68521 tttaaggagg aaagaacaat gacaaattac acagtagata ctttaaatct agggaaattt
    68581 attacagaat ctggggaagt catagataac ttgcgtttga gatatgagca tgttggttat
    68641 catggacaac cattagttgt agtttgtcat gcattaactg gcaatcattt aacatatgga
    68701 acagatgatt atccgggttg gtggcgagaa attattgatg ggggatatat acccattcac
    68761 gattatcaat ttttaacatt tgatgttatt ggtagtcctt tcggttcaag ttcaccttta
    68821 aacgaccctc attttcctaa aaaattaaca ttaagagata tagtcagagc gaatgaacga
    68881 ggtatacaag cccttggtta tgataagatt aatattttaa tagggggaag tcttggaggt
    68941 atgcaagcaa tggaactact ttacaatcaa cagtttgaag tagataaagc cattatcctt
    69001 gctgcaacaa gtcgaacatc atcttatagt agagctttca atgaaattgc aaggcaagcc
    69061 attcatcttg gtggtaagga aggtctaagt attgcacgcc aattaggttt tttgacatat
    69121 cgatcatcaa aaagttatga tgaacgtttc acgccggatg aagtagtcgc ataccaacaa
    69181 catcaaggta ataaatttaa agaacatttt gatttgaatt gttatctgac actgctagat
    69241 gtattggata gtcacaacat tgaccgaggt cgcacagacg taacgcatat ttttaaaaat
    69301 ttagaaacga aagtcttaac gatggggttc atagatgatt tgctatatcc ggacgatcaa
    69361 gttcgtgcat taggtgaacg ttttaaatat catcgtcatt tcttcgtgcc tgataatgtt
    69421 ggacatgatg gattcctact aaactttagt acctgggcac ctaacttata tcatttctta
    69481 aatttaaagc attttaagcg taagtaataa tgtatatatt tttaaagaat gaagctacta
    69541 aatcacagtt atcatattca aagacatcta gagtacatga gagtggaaat gaattgtaaa
    69601 tctaaatcaa gcttgattgc tatgtagtgg gattaaataa tcatgttgaa aatgaaagca
    69661 cacaaaagcg attcaaatga gtatgttaat tacttataaa acatgaaagt tattattcaa
    69721 ttaaatgaaa tagaagcata caatctataa attgttaatt tccattaaag aggttaaaat
    69781 aatagctata gttaaaaata tgggagtggc ttatgtgttt tcaaaaatac aacctaaagc
    69841 aacaataatt gcaacgatta cgttggtatt tgtcgcttta gctttatatc tagtgcctgg
    69901 tttgggacta atatttgcat tatttgcaac cataccaggt atcgttttat ggaataaatc
    69961 aatacaatct ttcggggtta gtgcacttat tacagtaatt ataacaactg ttttaggtaa
    70021 tactttcgtt ttaagtgcca tcatattagt cttaattgca agtttaatta ttggtcaatt
    70081 gctcaaagaa agaacgtcta aagaaagaat gttatacgta acaacagtag cgatgagctt
    70141 aatttcatta atcgctttta tgttactaca aacattcgga aggattccac catcagcgag
    70201 catagtaaaa cctttcaagc aaacattaca tgaagcgatt acgatgagcg gtgccgatgc
    70261 gaatatgacc caaatattag aagaagggtt tagacaagcg accgttcaat taccaggttt
    70321 catcattatc attacatttt taatcgtctt aattaactta atcgttacat ttccggtttt
    70381 acgaaaattt aaaatcgcta cacctgtatt taagccactt ttcgcgtggc aaatgagcgg
    70441 tattttatta tggatataca ttattgttat catatgttta ttatttacag gtcaaccgag
    70501 tgtgttccag agcattcttt taaacttcca acttgtgtta tcattagtaa tgtatattca
    70561 aggtttaagt gttattcatt tctttggtaa agcgaaaggt ttgccgaatg cagtaacgat
    70621 tttactattg attatcggta caatactgac acctacgaca catattgtag gactacttgg
    70681 tgttatcgat ttaagtttga atttgaagcg aatcatgaaa aataattcta aaaagtgaat
    70741 agaggtggaa taatgaatcg gcagtccact aagaaagctt tactaatacc atttgtcatc
    70801 atgatcatca cagcaattgt tttaatgggt gtatggttta tctttaatag tcttatagca
    70861 ttaattgcat ctatcgttct tgtcgtgatg attattgtta gcatcatttt attcagacaa
    70921 gctttaatga aaatggatag ttatgtagat ggtttgagtg ctcaaatttc aacaacaaat
    70981 aataaagcaa tcaaacattt accaattggt atcattgttt tagatgaaaa tgatcacatc
    71041 gaatgggtta accaatttat gacaaatcat atggaagcaa atgtcatttc tgaatctgta
    71101 aatgaagtat ttccaaacat tttaaagcaa ttagatagag tgaaatccgt tgaaatagaa
    71161 tataatcagt atcatttcca agtacgttat tctgagaatg atcattgcct ctatttcttt
    71221 gatataactg aacaagtaca aacaaatgaa ctatatgaaa attctaaacc aatcattgcg
    71281 acattatttt tagataacta cgatgagatt actcaaaata tgaatgatac gcagcgttcg
    71341 gaaatcaatt caatggtaac gcgtgttatt agtcgatggg caactgagta taatatattc
    71401 tttaaaaggt atagttccga tcaattcgta gcctatttaa atcaaaaaat attagctgac
    71461 ttagaagaat ctaaatttga tatcttgagt caattacgtg aaaaaagtgt tggttatcgt
    71521 gcccaattaa cattaagtat tggtgttggt gaaggtactg aaaatttaat cgatttaggt
    71581 gaattatcac aatcaggcct agacttagca ttagggcgcg gtggcgacca agttgcaatt
    71641 aaaagtatta atggtaatgt gcgtttctat ggcggtaaga ctgacccgat ggagaaacgt
    71701 actcgtgtaa gagcacgagt gatctcacat gcgttaaaag atatccttgc agagggtgac
    71761 aaagtcatta tcatgggaca taaacgtcct gacttagatg caattggtgc agcaatcggt
    71821 gtgtctagat ttgcaatgat gaataattta gaagcataca tcgtattaaa tgagactgac
    71881 attgatccaa cattacgacg cgtgatgaac gaaattgata aaaagtcaga gttaagagag
    71941 cgatttataa catcagatga tgcttgggat atgatgacat ctaagacaac cgtagtgatt
    72001 gttgatacgc ataaaccgga actggtttta gatgaaaatg tcttaaataa agcaaaccgt
    72061 aaagttgtta tcgatcatca tagacgtggt gaaagcttca tctctaatcc attgttgata
    72121 tatatggaac catacgcaag ttcaacagct gaattggtaa cagagttact ggaatatcaa
    72181 ccaacagaac aacgtttaac acgtcttgaa tcaacagtga tgtatgcagg tattattgta
    72241 gatacaagaa actttacatt acgaacagga tcaagaacat tcgatgcagc gagttattta
    72301 cgtgcacatg gtgcagatac gattttaacg caacatttct taaaagatga tgtggatact
    72361 tacattaatc gatctgaatt aattcgaact gtaaaagttg aagataatgg catagccatt
    72421 gcgcatggtt cagacgataa aatttatcat ccagtaacag ttgcacaagc agcagatgaa
    72481 ctgttaagtt tagaaggtat tgaagcatca tatgttgttg cgagacgtga agataatctg
    72541 attggtatat ctgcgcgttc actcggttca gtaaatgttc agttaacaat ggaagcactt
    72601 ggtggcggtg gacatttaac caatgctgca acacaactta aaggtgtgac agtcgaagag
    72661 gcgatagcac aattacaaca agcaattaca gaacaattaa gtaggagtga agatgcatga
    72721 aagtaatttt tacacaagat gttaaaggta aaggtaaaaa aggtgaagtt aaagaagtac
    72781 cagtaggtta tgcaaataac ttcttattga aaaagaatta tgctgtagaa gcaacaccag
    72841 gtaaccttaa acaattagag ttacagaaaa aacgtgcaaa acaagaacgc caacaagaaa
    72901 ttgaagatgc taaagcatta aaagaaacgt tatcaaacat tgaagttgaa gtatcagcaa
    72961 aaactggtga aggtggtaaa ttgtttggat cagtaagtac aaaacaaatt gccgaagcac
    73021 taaaagcaca acatgatatt aaaattgata aacgtaaaat ggatttacca aatggaattc
    73081 attccctagg atatacgaat gtacctgtta aattagataa agaagttgaa ggtacaattc
    73141 gcgtacacac agttgaacaa taaagttgga ttgaaataag aggtgtaacc attcatggat
    73201 agaatgtatg agcaaaatca aatgccacat aacaatgaag ctgaacagtc tgtcttaggt
    73261 tcaattatta tagatccaga attgattaat actactcagg aagttttgct tcctgagtcg
    73321 ttttataggg gtgcccatca acatattttc cgtgcaatga tgcacttaaa tgaagataat
    73381 aaagaaattg atgttgtaac attgatggat caattatcga cggaaggtac gttgaatgaa
    73441 gcgggtggcc cgcaatatct tgcagagtta tctacaaatg taccaacgac gcgaaatgtt
    73501 cagtattata ctgatatcgt ttctaagcat gcattaaaac gtagattgat tcaaactgca
    73561 gatagtattg ccaatgatgg atataatgat gaacttgaac tagatgcgat tttaagtgat
    73621 gcagaacgtc gaattttaga gctatcatct tctcgtgaaa gcgatggctt taaagacatt
    73681 cgagacgtct taggacaagt gtatgaaaca gctgaagagc ttgatcaaaa tagtggtcaa
    73741 acaccaggta tacctacagg atatcgagat ttagaccaaa tgacagcagg gttcaaccga
    73801 aatgatttaa ttatccttgc agcgcgtcca tctgtaggta agactgcgtt cgcacttaat
    73861 attgcacaaa aagttgcaac gcatgaagat atgtatacag ttggtatttt ctcactagag
    73921 atgggtgctg atcagttagc cacacgtatg atttgtagtt ctggtaatgt tgactcaaac
    73981 cgcttaagaa cgggtactat gactgaggaa gattggagtc gttttactat agcggtaggt
    74041 aaattatcac gtacgaagat ttttattgat gatacaccgg gtattcgaat taatgattta
    74101 cgttctaaat gtcgtcgatt aaagcaagaa catggcttag acatgattgt gattgactac
    74161 ttacagttga ttcaaggtag tggttcacgt gcgtccgata acagacaaca ggaagtttct
    74221 gaaatctctc gtacattaaa agcattagcc cgtgaattag aatgtccagt tatcgcatta
    74281 agtcagttat ctcgtggtgt tgaacaacga caagataaac gtccaatgat gagtgatatt
    74341 cgtgaatctg gttcgattga gcaagatgcc gatatcgttg cattcttata ccgtgatgat
    74401 tactataacc gtggcggcga tgaagatgat gacgatgatg gtggtttcga gccacaaacg
    74461 aatgatgaaa acggtgaaat tgaaattatc attgctaagc aacgtaacgg tccaacaggc
    74521 acagttaagt tacactttat gaaacaatat aataaattta ccgatatcga ttatgcacat
    74581 gcagatatga tgtaaaaaag tttttccgta caataatcat taagatgata aaattgtacg
    74641 gtttttattt tgttctgaac gggttgatat atgttaagtt tgtgtattga aagtgataaa
    74701 ttagtactgt caacgcctct gttaaagggt ttttaggacg ttgaagacga tttgttaaaa
    74761 tgatttttct tttaaaaagg ccgaaaatca atgttcgatt tttatttgca ttatggtctc
    74821 gatattggta gaatatcaaa tggttaaatg agaaaaactt ggaggtgctc acatgtcatc
    74881 aatcgtagta gttgggacac aatggggaga cgaaggaaaa ggaaaaataa cggatttctt
    74941 ggcagaacag tcagatgtta tcgcgcgttt ttcaggtggt aataatgcag gccataccat
    75001 tcaatttggc ggagaaacat ataaattaca tttagtacca tctggtatct tttacaaaga
    75061 caaattagcg gtaatcggta acggtgtcgt tgttgatcca gttgcactat tgaaagaatt
    75121 agacggatta aatgaacgtg gcattcctac aagtaattta cgtatatcta atcgtgcgca
    75181 agtgatttta ccatatcact tagcacaaga tgaatatgaa gaacgtttac gcggtgacaa
    75241 taagattggt acaactaaaa aaggtatcgg tccagcatat gtagacaaag ttcaacgtat
    75301 cggtattcgt atggcagatt tacttgaaaa agaaacattc gaaagattat taaaatcaaa
    75361 cattgaatat aaacaagcat atttcaaagg tatgtttaac gaaacatgtc catcatttga
    75421 tgatatcttt gaagaatact atgctgcagg tcaacgttta aaagaatttg taacagacac
    75481 atcaaaaatc ttagacgatg catttgtagc agatgaaaag gtacttttcg aaggtgcgca
    75541 aggtgtaatg ttagatatcg accatggtac atatccattc gttacatcaa gtaatccaat
    75601 tgcaggtaac gttactgttg gtacaggtgt aggtcctaca ttcgtttcga aggtaattgg
    75661 tgtatgtaaa gcttatacat cacgtgttgg tgatggtcca ttccctactg aattattcga
    75721 tgaagatgga catcatatta gagaagttgg tcgtgaatac ggtacaacaa caggacgtcc
    75781 acgtcgtgta ggttggtttg actcagttgt attacgtcac tctcgtcgtg taagtggtat
    75841 tacagattta tctattaact caatcgatgt tttaacaggc ctagacacag tgaaaatctg
    75901 tacagcttat gaattagacg gtaaagaaat tactgagtac ccagcaaact tagatcaatt
    75961 aaaacgttgt aaaccaatct ttgaagagtt accaggttgg acagaagacg taacaagtgt
    76021 gcgtacttta gaagaattac ctgaaaatgc acgtaaatat ttagagcgta tttcagaatt
    76081 atgtaatgta caaatttcta tcttctcagt tggtccagat agagaacaaa caaacctatt
    76141 aaaagaattg tggtagaact ttatataagt catacgcaat gattataaat acatgagcct
    76201 tctatcttta ttggtaggag gcttttgctt tgtttgcttc tgtatcgatt cgattattta
    76261 gataaaaatt actaacgtaa aggtgatatt tgctagtcat aatttaaaag attagatgat
    76321 atttaacaaa attaagaaga aatacttgaa tttaataagt ctgatgtcga aaatagctat
    76381 taaaatagag tagacgtaag tgtaaatgaa agtacctaaa atagaaaaat ttcaaaaata
    76441 gcgtaattat tataataaat agactgccaa taaaatgcaa tttttcactt ataacattct
    76501 tcaaaaaata atagcaaaat tatgtaaaaa atatcttgtc atggcaagat tggctgtgct
    76561 ataatctatc ttgtgcttaa gaacggctcc ttggtcaagc ggttaagaca ccgccctttc
    76621 acggcggtaa cacgggttcg agtcccgtag gagtcaccat tttttaggtc tcgtagtgta
    76681 gcggttaaca cgcctgcctg tcacgcagga gatcgcgggt tcgattcccg tcgagaccgt
    76741 acaaatgcct atccaagagg ataggcattt ttttgcgttt aatattatat taataaaaga
    76801 tatatggacg aatgataatc atattgattt atctgttcgt ccattttctt tataatgtat
    76861 gaacctcaag taacttagtg gttggatatg aaagataaac gtagacaata aaatctttat
    76921 tagacgtaca aacatatgct actgtcaaca tatttcttcg ttgtgatatg ccaccaatcc
    76981 tccataacat caattgttaa agtaacgaat aacgaataat gatatttatt ttctgagcaa
    77041 tgacgtgcaa ctagaagttg ccattaccct aattttatta ttggaataga gacctcatca
    77101 ttgtgttaaa tatcattatc ataatccgcc gtgagaaact aataaaaaat attaatatat
    77161 aagtttatat tggaaaatag aattaatagc ttataaatgg taaattatat aataggttac
    77221 tatacgttat aagacggaaa atgcgcacaa taacaaaaat agtaagcgac atcctgtgat
    77281 tttttacaca aacataaacg ataaagaaca aaaaatgata aaataatatt aatgatttaa
    77341 gaaaagaggt ttatgcaaat ggctagaaaa gttgttgtag ttgatgatga aaaaccgatt
    77401 gctgatattt tagaatttaa cttaaaaaaa gaaggatacg atgtgtactg tgcatacgat
    77461 ggtaatgatg cagtcgactt aatttatgaa gaagaaccag acatcgtatt actagatatc
    77521 atgttacctg gtcgtgatgg tatggaagta tgtcgtgaag tgcgcaaaaa atacgaaatg
    77581 ccaataataa tgcttactgc taaagattca gaaattgata aagtgcttgg tttagaacta
    77641 ggtgcagatg actatgtaac gaaaccgttt agtacgcgtg aattaatcgc acgtgtgaaa
    77701 gcgaacttac gtcgtcatta ctcacaacca gcacaagaca ctggaaatgt aacgaatgaa
    77761 atcacaatta aagatattgt gatttatcca gacgcatatt ctattaaaaa acgtggcgaa
    77821 gatattgaat taacacatcg tgaatttgaa ttgttccatt atttatcaaa acatatggga
    77881 caagtaatga cacgtgaaca tttattacaa acagtatggg gctatgatta ctttggcgat
    77941 gtacgtacgg tcgatgtaac gattcgtcgt ttacgtgaaa agattgaaga tgatccgtca
    78001 catcctgaat atattgtgac gcgtagaggc gttggatatt tcctccaaca acatgagtag
    78061 aggtcgaaac gaatgaagtg gctaaaacaa ctacaatccc ttcatactaa acttgtaatt
    78121 gtttatgtat tactgattat cattggtatg caaattatcg ggctgtattt tacaaataat
    78181 cttgaaaaag agctgcttga taattttaag aagaatatta cgcagtacgc taaacaatta
    78241 gaaattagta ttgaaaaagt atatgacgaa aagggctccg taaatgcaca aaaagatatt
    78301 caaaatttat taagtgagta tgccaaccgt caagaaattg gagaaattcg ttttatagat
    78361 aaagaccaaa ttattattgc gacgacgaag cagtctaacc gtagtctaat caatcaaaaa
    78421 gcgaatgata gttctgtcca aaaagcacta tcactaggac aatcaaacga tcatttaatt
    78481 ttaaaagatt atggcggtgg taaggaccgt gtctgggtat ataatatccc agttaaagtc
    78541 gataaaaagg taattggtaa tatttatatc gaatcaaaaa ttaatgacgt ttataaccaa
    78601 ttaaataata taaatcaaat attcattgtt ggtacagcta tttcattatt aatcacagtc
    78661 atcctaggat tctttatagc gcgaacgatt accaaaccaa tcaccgatat gcgtaaccag
    78721 acggtcgaaa tgtccagagg taactatacg caacgtgtga agatttatga taatgatgaa
    78781 attggcgaat tagctttagc atttaataac ttgtctaaac gtgtacaaga agcgcaggct
    78841 aatactgaaa gtgagaaacg tagactggac tcagttatca cccatatgag tgatggtatt
    78901 attgcaacag accgccgtgg acgtattcgt atcgtcaatg atatggcact caagatgctt
    78961 ggtatggcga aagaagacat catcggatat tacatgttaa gtgtattaag tcttgaagat
    79021 gaatttaaac ttgaagaaat tcaagagaat aatgatagtt ttttattaga tttaaatgaa
    79081 gaagaaggtc taatcgcacg tgttaacttt agtacgattg tgcaggaaac aggatttgta
    79141 actggttata tcgctgtgtt acatgacgtt actgaacaac aacaagttga acgtgagcgt
    79201 cgtgaatttg ttgccaatgt atcacatgag ttacgtacac ctttaacttc tatgaatagt
    79261 tacattgaag cacttgaaga aggtgcatgg aaagatgagg aacttgcgcc acaattttta
    79321 tctgttaccc gtgaagaaac agaacgaatg attcgactgg tcaatgactt gctacagtta
    79381 tctaaaatgg ataatgagtc tgatcaaatc aacaaagaaa ttatcgactt taacatgttc
    79441 attaataaaa ttattaatcg acatgaaatg tctgcgaaag acacaacatt tattcgagat
    79501 attccgaaaa agacgatttt cacagaattt gatcctgata aaatgacgca agtattcgat
    79561 aatgtcatta caaatgcgat gaaatattct agaggcgata aacgtgtcga gttccacgtg
    79621 aaacaaaatc cactttataa tcgaatgacg attcgtatta aagataatgg catcggtatt
    79681 cctatcaata aagtcgataa gatattcgac cgattctatc gtgtagataa ggcacgtacg
    79741 cgtaaaatgg gtggtactgg attaggacta gccatttcga aagagattgt ggaagcgcac
    79801 aatggtcgta tttgggcaaa cagtgtagaa ggtcaaggta catctatctt tatcacactt
    79861 ccatgtgaag tcattgaaga cggtgattgg gatgaataat aaggaacata ttaaatctgt
    79921 cattttagcg ctactcgtct tgatgagtgt cgtattgaca tatatggtat ggaacttttc
    79981 tcctgatatt gcaaatgtcg acaatacaga tagtaagaag agtgaaacga aacctttaac
    80041 gacacctatg acagccaaaa tggatacaac tattacgcca tttcagatta ttcattcgaa
    80101 aaatgatcat ccagaaggta cgattgcgac ggtatctaat gtgaataaac tgacgaaacc
    80161 tttgaaaaat aaagaagtga agtccgtgga acatgttcgt cgtgatcata acttgatgat
    80221 tccggattta agcagtgatt ttacattatt cgattttacg tatgatttac cgttatcaac
    80281 atatcttggc caagtactga acatgaatgc gaaagtacca aatcatttca atttcaatcg
    80341 tttagtcata gatcatgatg ctgatgataa tatcgtgctt tatgctataa gtaaagaccg
    80401 ccacgattac gtaaaattaa caactacaac gaaaaatgat cattttttag atgcattagc
    80461 agcagtgaaa aaagatatgc aaccatacac agatatcatc acaaacaaag atacaattga
    80521 tcgtacgacg catgtttttg caccaagtaa acctgaaaag ttaaaaacat atcgcatggt
    80581 atttaacacg attagtgttg agaaaatgaa tgctatacta tttgacgatt caaccatcgt
    80641 tcgtagttca aagagtggtg ttacaaccta caacaataat acaggtgtcg caaactataa
    80701 cgataaaaat gaaaaatatc attataaaaa cctgtccgaa gatgaagcaa gttccagcaa
    80761 aatggaagaa acgattccag gaacctttga ttttattaat ggtcatggtg gtttcttaaa
    80821 cgaagacttc agattgttta gtacgaataa tcagtcaggc gagttaacat atcaacgttt
    80881 ccttaacggt tatccaacgt ttaataaaga aggctctaat caaattcaag tcacttgggg
    80941 tgaaaaaggc gtctttgatt atcgtcgttc gttattgcgc accgacgttg tgttaaatag
    81001 tgaggataat aaaacgttgc cgaaattaga gtctgtacgt tcaagcttag cgaacaatag
    81061 tgatattaat tttgaaaaag taacaaacat cgctatcggt tacgaaatgc aggataactc
    81121 agatcataat cacattgaag tgcagattaa cagtgaactc gtaccgcgtt ggtatgtaga
    81181 atatgatggt gaatggtatg tttataacga tgggaggctt gaataaatga actggaaact
    81241 gacaaagaca cttttcattt tcgtgtttat tcttgtcaac atcgtgttag tatcgattta
    81301 tgttaataaa gtcaatcgct cacacattaa tgaagttgag agtaacaatg aagttaattt
    81361 tcagcaagaa gaaattaaag taccggctag tatattgaat aaatcagtta aaggtataaa
    81421 attagagcaa attacagggc gatcaaaaga ctttagttct aaagctaagg gcgattcgga
    81481 tttgaccaca tcagatggtg gaaaattatt gaatgcgaac attagtcaat cggtaaaggt
    81541 cagtgacaat aacttaaaag atttgaaaga ttatgttaac aaacgtgtgt tcaaaggttc
    81601 agaatatcaa ttaagtgaaa ttaattctgg ttctgtaaaa tacgaacaaa cgtatgataa
    81661 tttcccgatt ttgaacaata gtaaagcgat gttgaacttt aatatagaag ataacaaagc
    81721 ggctagttat aaacaatcaa tgatggatga cattaagccc acagatggtg cagataagaa
    81781 gcatcaagtt attggagtga gaaaagcaat cgaggcatta tattataatc gttacttgaa
    81841 aaaaggtgat gaagtcatta atgctagact cggttactac tcagtcgtga acgaaacgaa
    81901 tgttcaattg ttacaaccaa actgggaaat taaagtgaag catgacggta aggacaaaac
    81961 gaatacttac tatgtcgaag cgacaaataa taaccctaaa attattaatc attaatatga
    82021 atcgtaataa gctagtattg caagctcatc atatgtgaga agcggtgcta gctttttgct
    82081 ggtatgggtt ttcatggatg acatttctgc gtctctaatg tgcgcattta ttcatatttt
    82141 aagtagaacc gcattttaaa attaacgtaa ctgctatttt aaaaacttta gtatttgtct
    82201 aatcattgtt ataataatta agaaattcat tgcacgtgat tatcaaaatt taaatataag
    82261 aaaccggtcg atgaactaaa gttacataat aggaaaggta tacaaaacag ctaatatact
    82321 gatagtttct gtagggaaaa tcgtatattt gcactgatgt atattgcagt catatagaga
    82381 gattgactgt ttaaagagaa aggatgagcc gcttgatacg catgagtgta ttagcaagtg
    82441 gtagtacagg taacgccact tttgtagaaa atgaaaaagg tagtctatta gttgatgttg
    82501 gtttgactgg caagaaaatg gaagaattgt ttagtcaaat tgaccgtaat attcaagatt
    82561 taaatggtat tttagtaacc catgaacata ttgatcatat taaaggatta ggtgttttgg
    82621 cgcgtaaata tcaattgcca atttatgcga atgaaaagac ttggcaggca attgaaaaga
    82681 aagatagtcg catccctatg gatcagaaat tcatttttaa tccttatgaa acaaaatcta
    82741 ttgcaggttt cgatgttgaa tcgtttaacg tgtcacatga tgcaatagat ccgcaatttt
    82801 atattttcca taataactat aagaagttta cgattttaac ggatacgggt tacgtgtctg
    82861 atcgtatgaa aggtatgata cgtggcagcg atgcgtttat ttttgagagt aatcatgacg
    82921 tcgatatgtt gagaatgtgt cgttatccat ggaagacgaa acaacgtatt ttaggcgata
    82981 tgggtcatgt atctaatgag gatgcgggtc atgcgatgac agatgtgatt acaggtaaca
    83041 cgaaacgtat ttacctatcg catttatcac aagacaataa catgaaagat ttggcgcgta
    83101 tgagtgttgg ccaagtattg aacgaacacg atattgatac ggaaaaagaa gtattgctat
    83161 gtgatacgga taaagctatt ccaacgccaa tatatacaat ataaatgaga gtcaccctat
    83221 aaagttcggc actgctgtga gacgacttta tcgggtgctt ttttatgtta ttggtgggaa
    83281 atggctgttg ttggaattaa ggttctattt gaaatgtaaa aaataattcg atattaaatg
    83341 taatttataa ataatttaca taaaatcaat cattttaata taaggattat gataatatat
    83401 tggtgtatga cagttaatgg agggaacgaa atgaaagctt tattacttaa aacaagtgta
    83461 tggctcgttt tgctttttag tgtgatggga ttatggcaag tctcgaacgc ggctgagcag
    83521 tatacaccaa tcaaagcaca tgtagtaaca acgatagaca aagcaacaac agataagcaa
    83581 caagtaacgc caacaaagga agcggctcat caatttggtg aagaagcggc aaccaacgta
    83641 tcagcatcag cacagggaac agctgatgaa ataaacaata aagtaacatc caacgcattt
    83701 tctaacaaac catctacagc agtttcaaca aaagtaaacg aaacgcacga tgtagataca
    83761 caacaagcct caacacaaaa accaactcaa tcagcaacat tcacattatc aaatgctaaa
    83821 acagcatcac tttcaccacg aatgtttgct gccaatgtac cacaaacaac aacacataaa
    83881 atattacata caaatgatat ccatggccga ctagccgaag aaaaagggcg tgtcatcggt
    83941 atggctaaat taaaaacaat aaaagaacaa gaaaagcctg atttaatgtt agacgcagga
    84001 gacgccttcc aaggtttacc actttcaaac cagtctaaag gtgaagaaat ggctaaagca
    84061 atgaatgcag taggttatga tgctatggca gtgggtaacc atgaatttga ctttggatac
    84121 gatcagttga aaaagttaga gggtatgtta gacttcccga tgctaagtac taacgtttac
    84181 aaagatggga aacgcgcgtt taagccttca acaattgtaa cgaaaaatgg tattcgttat
    84241 ggaattattg gcgtaacgac accagaaaca aagacgaaaa caagacctga gggcattaaa
    84301 ggtgttgaat ttagagatcc attacaaagt gtgacagcag aaatgatgcg tatttataaa
    84361 gacgtagata catttgttgt tatatcacat ttagggattg atccttcaac acaagaaaca
    84421 tggcgtggtg attacttagt gaaacaatta agtcaaaatc cacaattgaa gaaacgtatt
    84481 acagtcattg atggtcattc acataccgta cttcaaaatg gtcaaattta taacaatgat
    84541 gcattagcac aaacaggtac agcacttgcg aatatcggta aggttacatt taattaccgc
    84601 aatggagagg tatcaaatat taaaccgtca ttgattaatg ttaaagacgt tgaaaatgta
    84661 acaccgaaca aagcattagc tgaacaaatt aatcaagctg atcaaacatt tagagcacaa
    84721 acagcagagg ttattattcc aaataatacc attgatttca aaggagaaag agatgacgtt
    84781 agaacgcgtg aaacaaattt aggaaacgcg attgcagatg ctatggaagc gtatggcgtt
    84841 aagaatttct ctaaaaagac tgactttgcc gtgacaaatg gtggaggtat tcgtgcctct
    84901 atcgcaaaag gtaaggtgac acgctatgat ttaatctcag tattaccatt tggaaatacg
    84961 attgcgcaaa ttgatgtaaa aggttcagac gtctggacag ctttcgaaca tagtttaggt
    85021 gcaccaacaa cacaaaaaga cggtaagaca gtattaacag cgaatggcgg tttactacat
    85081 atctctgatt caattcgtgt ttactatgat atgaataaac cgtctggcaa acgaattaac
    85141 gctattcaaa ttttaaataa agagacaggt aagtttgaaa atattgattt aaaacgtgta
    85201 tatcatgtaa cgatgaatga cttcacagca tcaggtggcg acggatatag tatgttcggt
    85261 ggccctagag aagaaggtat ttcattagat caagtactag caagttattt aaaaacagct
    85321 aacatagcta agtatgatac gacagaacca caacgtatgt tattaggtaa accagcagta
    85381 agtgaacaac cagctaaagg acaacaaggt agcaaaggta gtgagtctgg taaagatgta
    85441 caaccaattg gtgacgacaa agcgatgaat ccagcgaaac aaccagcgac aggtaaagtt
    85501 gtattgttac caacgcatag aggaactgtt agtagcggta cagaaggttc tggtcgcaca
    85561 ttagaaggag ctactgtatc aagcaagagt gggaaccaat tggttagaat gtcagtgcct
    85621 aaaggtagcg cgcatgagaa acagttacca aaaactggaa ctaatcaaag ctcaagccca
    85681 gcagcgatgt ttgtattagt agcaggtata ggtttaatcg cgactgtacg acgtagaaaa
    85741 gctagttaaa atatattgaa aacaatacta ctgtatttct taaataagag gtacggtagt
    85801 gtttttttat ggaaaaaagc tataaacgtt gataaacatg ggatataaaa acggggataa
    85861 gtaataagac atcaaggtgt ttatccacag aaatggggat agttatccag aattgtgtac
    85921 aatttaaaga gaaataccca caatgcccac agagttatcc acaaatacac aagttataca
    85981 ctaaaaattg ggcataaatg tcaggaaaat atcaaaaact gcaaaaaata ttggtataat
    86041 aagagggaac agtgtgaaca agttaataac ttgtggataa ctggaaagtt gataacaatt
    86101 tggaggacca aacgacatga aaatcaccat tttagctgta gggaaactaa aagagaaata
    86161 ttggaagcaa gccatagcag aatatgaaaa acgtttaggc ccatacacca agatagacat
    86221 catagaagtt ccagacgaaa aagcaccaga aaatatgagc gacaaagaaa ttgagcaagt
    86281 aaaagaaaaa gaaggccaac gaatactagc caaaattaaa ccacaatcca cagtcattac
    86341 attagaaata caaggaaaga tgctatcttc cgaaggattg gcccaagaat tgaaccaacg
    86401 catgacccaa gggcaaagcg actttgtatt cgtcattggc ggatcaaacg gcctgcacaa
    86461 ggacgtctta caacgcagta actacgcact atcattcagc aaaatgacat tcccacatca
    86521 aatgatgcgg gttgtgttaa ttgagcaagt gtatagagca tttaagatta tgcgtggaga
    86581 agcatatcat aaatgatgcg gttttttcag ccgcttcata aagggatttt gaatgtatca
    86641 gaacatatga ggtttatgtg aattgctgtt atgtttttaa gaagcttatc ataagtaatg
    86701 aggttcatga tttttgacat agttagcctc cgcagtcttt catttcaagt aaataatagc
    86761 gaaatattct ttatactgaa tacttatagt gaagcaaagt tctagctttg agaaaattct
    86821 ttctgcaact aaatatagta aattacggta aaatataaat aagtacatat tgaagaaaat
    86881 gagacataat atattttata ataggaggga atttcaaatg atagacaact ttatgcaggt
    86941 ccttaaatta attaaagaga aacgtaccaa taatgtagtt aaaaaatctg attgggataa
    87001 aggtgatcta tataaaactt tagtccatga taagttaccc aagcagttaa aagtgcatat
    87061 aaaagaagat aaatattcag ttgtagggaa ggttgctact gggaactata gtaaagttcc
    87121 ttggatttca atatatgatg agaatataac aaaagaaaca aaggatggat attatttggt
    87181 atatcttttt catccggaag gagaaggcat atacttatct ttgaatcaag gatggtcaaa
    87241 gataagtgat atgtttccgc gggataaaaa tgctgcaaaa caaagagcat taactttatc
    87301 ttccgaactc aataaatata ttacatcaaa tgaatttaat actggaagat tttattacgc
    87361 agaaaataaa gattcatctt atgatttaaa aaatgattat ccatcaggat attctcatgg
    87421 atcaataaga ttcaaatatt atgatttgaa tgaaggattc acagaagaag atatgctaga
    87481 ggatttaaag aaatttttag aactatttaa tgaattagct tcaaaagtta caaaaacatc
    87541 ctatgatagc ttggtcaata gcatagacga aatacaggaa gacagcgaaa ttgaagaaat
    87601 tagaacagca caaaaagata agacactcaa ggaagtggaa gcacctaaag gaataattcc
    87661 aaaatataaa aaaggtgtat caaagactac taaaaatgat tcagaaattg aaaaatcaaa
    87721 taaagagaat aaattaaccg gtaaagttgg agaaaaatta gcgctaaatt actttaatga
    87781 gctaattgat aataaaatag acgaagataa gaaagaacag tttaggaata ttttaaatga
    87841 taatccaggc tctcaacacg gtcatggcta tgatttagta gcttttgatc caacaaatac
    87901 agataaagct gtagaaaaat ttattgaaat taaaacatct acatcttcta gtattgagga
    87961 accatttttt atgtcgctaa atgaaatgtt tgctatgaaa gaatataagc agaaatattt
    88021 aatattaaga atatttaatg tttccggtaa agaaccacaa ttttatttta tagatccata
    88081 tgcaaattat tctgaattta aagatgtaga tgatctcatt gacaaagtat ttaatgtaga
    88141 agctattcag tataaagttt ttggcgaaaa at
//
LOCUS       DAPDIM010000004        76722 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000004 DAPDIM010000000
VERSION     DAPDIM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 76722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76722
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.004"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..184
                     /locus_tag="RFE25_000269"
     CDS             <1..184
                     /locus_tag="RFE25_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YdeI/OmpD-associated family protein"
                     /protein_id="HDU2815373.1"
                     /translation="ELEAKFEEMPQLESSFYKLTPGRQHQYIYHIGQAKRSETRQKRV
                     EKYINQILEGKGMHDK"
     gene            188..328
                     /locus_tag="RFE25_000270"
     CDS             188..328
                     /locus_tag="RFE25_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815374.1"
                     /translation="MSKAYRLYNNIQDDTKQPMAHAVGCFFRCVCHGQHFDVGIPLQA
                     WE"
     gene            408..527
                     /locus_tag="RFE25_000271"
     CDS             408..527
                     /locus_tag="RFE25_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815375.1"
                     /translation="MGGCPSVTMDACALLQKFDFCNNISHFRHFFAIKQPIER"
     gene            854..2080
                     /locus_tag="RFE25_000272"
     CDS             854..2080
                     /locus_tag="RFE25_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815376.1"
                     /translation="MLSIKHLTKIYSGNKKAVDDISLDIQSGEFIAFIGTSGSGKTTA
                     LRMINRMIEATEGQIEIDGKDVRSMNPVELRRNIGYVIQQIGLMPHMTIKENIVLVPK
                     LLKWTKEEKDKRAKELIKLVDLPESFLERYPAELSGGQQQRIGVVRALAAEQDIILMD
                     EPFGALDPITRDTLQDLVKTLQRKLGKTFIFVTHDMDEAIKLADKICIMSEGKVVQFD
                     TPDNILRHPANDFVRDFIGQNRLIQDRPNDKTVEGVMIKPITIQADATLNDAVHIMRQ
                     KRVDTIFVVDSNNHLLGFLDIEDINQGIRGHKSLRDTMQQHIYTVQIDSKLQDSVRTI
                     LKRNVRNVPVVDDKQRLVGLITRANVVDIVYDTIWGDSEDAVQTEHVGEDTVSSKMHE
                     QHTTNVKVRDIGDDKS"
     gene            2077..2712
                     /locus_tag="RFE25_000273"
     CDS             2077..2712
                     /locus_tag="RFE25_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815377.1"
                     /translation="MIEFLHEHGGQLMSKTLEHFYISIVALLLAIIVAVPIGILLSKT
                     KRTANIVLTVAGVLQTIPTLAVLAIMIPIFGVGKTPAIVALFIYVLLPILNNTVLGVQ
                     NIDSNIKEAGKSMGMTQFQLMKDVELPLALPLIIGGIRLSSVYVISWATLASYVGAGG
                     LGDFIFNGLNLYDPLMIVTATVLVTALALGVDALLALVEKWVVPKGLKVSG"
     gene            2729..3670
                     /locus_tag="RFE25_000274"
     CDS             2729..3670
                     /locus_tag="RFE25_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HDU2815378.1"
                     /translation="MKKIKYILVVFVLSLTVLSGCSLPGLGSKSTKNDVKITALSTSE
                     SQIISHMLRLLIEHDTHGKIKPTLVNNLGSSTIQHNALINGDANISGVRYNGTDLTGA
                     LKEAPIKDPKKAMIATQQGFKKKFDQTFFDSYGFANTYAFMVTKETAKKYHLETVSDL
                     AKHSKDLRLGMDSSWMNRKGDGYEGFKKEYGFDFGTVRPMQIGLVYDALNTEKLDVAL
                     GYSTDGRIAAYDLKVLKDDKQFFPPYAASAVATNELLRQHPELKTTINKLTGKISTSE
                     MQRLNYEADGKGKEPAVVAEEFLKKHHYFDKQKGGHK"
     gene            3670..4365
                     /locus_tag="RFE25_000275"
     CDS             3670..4365
                     /locus_tag="RFE25_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815379.1"
                     /translation="MEGNLLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIP
                     LGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGLGSETVVLTVFLYALLPII
                     KNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAV
                     GSFIGAPTLGDIVIRGTNATDGTTFILAGAIPIAIIAIVIDVLLRFLEKRLDPTTRHR
                     KNQSNHRPQSINM"
     gene            4659..6059
                     /locus_tag="RFE25_000276"
     CDS             4659..6059
                     /locus_tag="RFE25_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2815380.1"
                     /translation="MDTSKQFRGDNRLLLGIVLGVITFWLFAQSLVNLVVPLQSTYSS
                     DVGTINIAVSLSALFAGLFIVGAGDVADKFGRVKITYVGLILNVVGSLLIIITPLPAF
                     LIIGRIIQGLSAACIMPSTLAIINEYYIGTRRQRALSYWSIGSWGGSGICTLFGGLMA
                     TYIGWRSIFVVSILLTLLAMYLIKHAPETKAEPIKGMKAEAKKFDVIGLVILVVTMLS
                     LNVIITQTSHFGLVSPLILGLIVVFICSLVGFVYYENKIKHPLVDFSIFKNRGYSGAT
                     ISNFLLNGVAGGALIVINTYYQQQLGFNSSQTGYISLTYLIAVLSMIRVGEKILSQHG
                     PKRPLLLGSGFTVIGLILLSLTFLPEVWYIISSIVGYLLFGTGLGLYATPSTDTAVAS
                     APDDKSGVASGVYKMASSLGNAFGVAVSGTVYTVLAANLNLNLGGFTGMMFNALLAIV
                     AFLVILLLVPKNQTNL"
     gene            6285..7220
                     /locus_tag="RFE25_000277"
     CDS             6285..7220
                     /locus_tag="RFE25_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDU2815381.1"
                     /translation="MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGL
                     NITINGEAFELNIPMYHFNDQRDESIYDVVFLFPKSMQLKEVMEDMKPHIDNETIVVC
                     TMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
                     IKVADLLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLI
                     YKLTQEIVHVATIDNVHLNVDEVFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYIN
                     GAVATLGKQRHIEAPVNRFITDLIHTKESQRHAQD"
     gene            7542..8393
                     /locus_tag="RFE25_000278"
     CDS             7542..8393
                     /locus_tag="RFE25_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDU2815382.1"
                     /translation="MSKIFVTGATGLIGIKLVQRLKEEGHEVAGFTTSENGQQKLAAI
                     NVKAYIGDILKADTIDQALADFKPEIIINQITDLKNVDMAANTKVRIEGSKNLIDAAK
                     KHDVKKVIAQSIAFMYEPGEGLANEETSLDFNSTGDRKVTVDGVVGLEEETARMDEYV
                     VLRFGWLYGPGTWYGKDGMIYNQFMDGQVTLSDGVTSFVHLDDAVETSIQAIHFENGI
                     YNVADDAPVKGSEFAEWYKEQLGVEPNIDIQPAQPFERGVSNEKFKAQGGTLIYKTWK
                     DGMNPIK"
     gene            complement(8485..9981)
                     /locus_tag="RFE25_000279"
     CDS             complement(8485..9981)
                     /locus_tag="RFE25_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDU2815383.1"
                     /translation="MTTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQID
                     KIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDVDKKVKASPTTKYEIASNTKAFT
                     GLAILKLAQEGRLNLNDDVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDA
                     VTNKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSW
                     LKPLHMTHTSFKQTNNKSKHDAIGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEH
                     WIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNNDEHLVFHSGTLDNFS
                     SFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASILNQYKDQFNIV
                     TVLMTTLILLAFIFSAYRAWQMRHGQILLRRSKRIAVLSWLTLCLCIAIALILYALPY
                     LILGSNNWSFVLTWLPIEIKLALITTLIALFSTLIVILLFLHTKITKT"
     gene            10213..12042
                     /locus_tag="RFE25_000280"
     CDS             10213..12042
                     /locus_tag="RFE25_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDU2815384.1"
                     /translation="MFNQFKRLIIGQPKKNRELKDEKISKFKGLAILSSDALSSVAYG
                     PEQILITLSVVGAVATWYTLPIAGAVLILLAALIMSYRQIIYAYPKGGGAYMVSKTNL
                     GEKWGLLAGGSLLVDYILTVAVSISSGADAFVAAFPSLYGHKVLIACLLVLFILILNL
                     RGLTESATVLSYPVYLFIIGLVILIFIGTFRVATGDIQPHMHASVGTAVPGVTLFLLL
                     KAFSSGASSLTGVEAISNAVTNFREPSANNAVKTLIAMGSILAFLLVGIVGLAYVYGI
                     MPQTETTVLSQLAMQIFGDNAAFYFVQATTVMILVLAANTGFTAFPMLAASMSKDKYM
                     PRMFTVRGDRLGYSNSIIILGVLAIILIIVFDGMTEDLIPLYAVGVFIPFTLAQFGMV
                     IKWIHERPKNWLSKLSVNLLGGIVTFIVFMILLITKFSQVWPILIFLPFVVIFFLKIN
                     KHYRDIAEQLRSDIDVLNVDVVDRNLAIVPITSITTAVDKSIYYAQMLANNDVIAVHV
                     SFGDEDEKAFQEKWKRHFPDVRLVILHSEYRSIIRPISRFIDKINRKANDQNYMITVV
                     IPEFITKKRWHNLLHNQTSLRMKLYLIYQKNVNVCTIPFKLKK"
     gene            complement(12183..14261)
                     /locus_tag="RFE25_000281"
     CDS             complement(12183..14261)
                     /locus_tag="RFE25_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDU2815385.1"
                     /translation="MALLEAFLIFIFAVIISSVINNRFPQIPTAFIQIALGVVIFIIP
                     IQVDFQFNSEVFMFAVIAPLLFVEGTHVSRTKLLEYRKPILLMSMALVFATVVGVGYF
                     IHWIWPALPMPAAFAIAAILCPTDAVAVSAITRGKLLPKGSMTILEGESLLNDAAGII
                     SFKIAVTALVTGTFSLFQAVEQFIISTILGVLIGAIIGFVVVRIRIDLTANKGLKDNN
                     TLTFIQLLTPFVVYFLAEEVHASGIIAVVIAGLIHGLERDRLIRAQTELQMNYHQIWN
                     TFSYALNGFVFVVLGFMIPTVVIDIFQTEPDNFSFLIVITILIAIAIYACRFVWVYFW
                     YKDFYFPKNIQSYLDEEHDSHETPPSRVRYAFIMTMCGIHGTISLSMALTLPFIITKG
                     QAFEYRNDLLFIASFMVLISLILAQIVLPLITPSAEDTTFKGMTYQSAKIFIVQKVIQ
                     HFKNESKKDKNDTNYRPVLNQYYGELLFLLNSEPNNQNTKELKRLEDIAKVIETSTLE
                     RLIDKGKATYQDINNYRNIVELTETHRTASFVEKFANFFKMLWLRLKAMKHYKALNKE
                     SKKQEFENSFKDVQKIMRIVNHNIILRLKEEQNSTNVLEVSLVINHYYDMSRSLKWRA
                     QRRKERQENSNQIIPQAMFHNHKLEALYLQRHLLDELIRKNKINNIVAAQIRENINYN
                     EIVLSLQSKH"
     gene            complement(14399..15808)
                     /locus_tag="RFE25_000282"
     CDS             complement(14399..15808)
                     /locus_tag="RFE25_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDU2815386.1"
                     /translation="MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLF
                     TYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSM
                     SDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIA
                     MVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGV
                     TAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIG
                     VPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSML
                     VSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKN
                     SKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAE
                     KLAYEQRQNDSGHFRYDNQ"
     gene            16094..16900
                     /locus_tag="RFE25_000283"
     CDS             16094..16900
                     /locus_tag="RFE25_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDU2815387.1"
                     /translation="MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDI
                     SNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPF
                     IVNEEWAIIGHTGWYDYSFAAQRFSLEHLQKGKHYGATWQDKERISWGISDQNLSKIA
                     AEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDI
                     PYSIMGHVHFRKSVMDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI"
     gene            complement(16963..17618)
                     /locus_tag="RFE25_000284"
                     /pseudo
     CDS             complement(16963..17618)
                     /locus_tag="RFE25_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
     gene            17731..18204
                     /locus_tag="RFE25_000285"
     CDS             17731..18204
                     /locus_tag="RFE25_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDU2815388.1"
                     /translation="MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIA
                     DLQLKNNGDLAGILGLCIPELDGKMSYMIAVTGDNSADIAKYDIITLASSKYMVFEAQ
                     GAVPKAVQQKMEEVHHYIHQYQANTVKSAPFFELYQDGDTTSEKYITEIWMPVKG"
     gene            complement(18327..19538)
                     /locus_tag="RFE25_000286"
     CDS             complement(18327..19538)
                     /locus_tag="RFE25_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HDU2815389.1"
                     /translation="MQSTKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDF
                     GSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQL
                     PLFLTLRFIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGL
                     ALSVATWRSIFTILTIVALIILIGVASQLPKTSKDELKQVNFSSVIKDFGSLLKKPAF
                     IIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLV
                     EKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMA
                     MEERTGGSGNASSLLGLFQFILGGAVAPLVGLKGEFNTSPYMIIIFITAILLVSLQII
                     YFKMIKKQHVA"
     gene            complement(19720..20379)
                     /locus_tag="RFE25_000287"
     CDS             complement(19720..20379)
                     /locus_tag="RFE25_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815390.1"
                     /translation="MKRTDKYRDSYQYDNQNQNHRRQSEDASYRQQYAKGDPEEHPER
                     YYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDP
                     KVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKVDS
                     KLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDDNGGA
                     N"
     gene            complement(20439..21581)
                     /locus_tag="RFE25_000288"
     CDS             complement(20439..21581)
                     /locus_tag="RFE25_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDU2815391.1"
                     /translation="MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIP
                     MADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDL
                     LEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVKFTDV
                     NGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGA
                     DAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVV
                     FDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENY
                     QHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ"
     gene            21849..22235
                     /gene="gtxA"
                     /locus_tag="RFE25_000289"
     CDS             21849..22235
                     /gene="gtxA"
                     /locus_tag="RFE25_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase GtxA"
                     /protein_id="HDU2815392.1"
                     /translation="MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHI
                     TGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAE
                     IAPFAGLVITIPITFVLSKWILKDSN"
     gene            22369..22476
                     /locus_tag="RFE25_000290"
     CDS             22369..22476
                     /locus_tag="RFE25_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDU2815393.1"
                     /translation="MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK"
     gene            23179..24942
                     /locus_tag="RFE25_000291"
     CDS             23179..24942
                     /locus_tag="RFE25_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815394.1"
                     /translation="MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVF
                     KIILMMINNAYTINSIMVYIFIALITYISQVCCFGASTMLSHITAYEILSEIRKKLAQ
                     KLMRLPLGVVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSAAIFLYIMLID
                     WRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQ
                     SQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLN
                     YAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQH
                     YEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVT
                     SGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAK
                     LAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATAYVDP
                     DNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGN
                     YKKMWDTHMHTKDWGINTGHN"
     gene            24967..26700
                     /locus_tag="RFE25_000292"
     CDS             24967..26700
                     /locus_tag="RFE25_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815395.1"
                     /translation="MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIF
                     NNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKL
                     KNVRLGYFNSHHSNELTTIVTTDLTFLENFAMKMVDIIVNGYILITVLILSLLVVSWQ
                     VSLLACIGVLLSFFAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKEN
                     TSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLP
                     TLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNEN
                     IAFQNVNFSYDDKQVIKNVNFEIPTQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIR
                     IDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRAAKQACCH
                     DFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQL
                     IQTAINELSKGKTVITIAHKLETIKNADQIIVLNEGEIIQKGSHDELIRKPGMYQDFI
                     RIKSKSAGWKL"
     gene            26931..27098
                     /locus_tag="RFE25_000293"
                     /pseudo
     CDS             26931..27098
                     /locus_tag="RFE25_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501179.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27153..27839
                     /gene="bioD"
                     /locus_tag="RFE25_000294"
     CDS             27153..27839
                     /gene="bioD"
                     /locus_tag="RFE25_000294"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HDU2815396.1"
                     /translation="MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCVFKPFQTEERQ
                     DGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDK
                     EFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAVVHQDY
                     VNKNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLI
                     GVKNELHTTT"
     gene            27817..29175
                     /gene="bioA"
                     /locus_tag="RFE25_000295"
     CDS             27817..29175
                     /gene="bioA"
                     /locus_tag="RFE25_000295"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HDU2815397.1"
                     /translation="MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDT
                     NGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEI
                     TPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAV
                     SVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEIMTAILTNIEQILIERNDEIA
                     GFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHED
                     VQPDIMCLGKAITGGYLPLAATLTSQKIYNTFLSDSHGVNTFFHGHTYTGNQIVCTVA
                     LENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKT
                     PLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDR
                     KC"
     gene            29177..30184
                     /gene="bioB"
                     /locus_tag="RFE25_000296"
     CDS             29177..30184
                     /gene="bioB"
                     /locus_tag="RFE25_000296"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDU2815398.1"
                     /translation="MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYF
                     GKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGT
                     YCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYN
                     HNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFAL
                     KEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNL
                     RSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRA
                     N"
     gene            30162..31277
                     /locus_tag="RFE25_000297"
     CDS             30162..31277
                     /locus_tag="RFE25_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase
                     family protein"
                     /protein_id="HDU2815399.1"
                     /translation="MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSND
                     YLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILN
                     SGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEK
                     YPNQNIPKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGV
                     DILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLIN
                     ADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFT
                     SYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED"
     gene            31288..31980
                     /locus_tag="RFE25_000298"
     CDS             31288..31980
                     /locus_tag="RFE25_000298"
                     /EC_number="6.2.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxyhexanoate--CoA ligase"
                     /protein_id="HDU2815400.1"
                     /translation="MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENG
                     QPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETV
                     YTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPY
                     VKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGGIIFVDDCIDLNHYISFL
                     ESTPKQVVYETV"
     gene            31991..32458
                     /locus_tag="RFE25_000299"
     CDS             31991..32458
                     /locus_tag="RFE25_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDU2815401.1"
                     /translation="MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLIL
                     AFFGIKKYFLGGLLSSVLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLSS
                     VLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR"
     gene            complement(32510..33487)
                     /gene="hlgB"
                     /locus_tag="RFE25_000300"
     CDS             complement(32510..33487)
                     /gene="hlgB"
                     /locus_tag="RFE25_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component gamma-hemolysin HlgAB/HlgCB subunit
                     B"
                     /protein_id="HDU2815402.1"
                     /translation="MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTL
                     YKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKL
                     YWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNG
                     NTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNEL
                     FLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMD
                     LYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK"
     gene            complement(33489..34436)
                     /gene="hlgC"
                     /locus_tag="RFE25_000301"
     CDS             complement(33489..34436)
                     /gene="hlgC"
                     /locus_tag="RFE25_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component gamma-hemolysin HlgCB subunit C"
                     /protein_id="HDU2815403.1"
                     /translation="MLKNKILATTLSVSLLALLANPLLENAKAANDTEDIGKGSDIEI
                     IKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKA
                     MRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSF
                     NYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKD
                     PRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTH
                     YGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN"
     gene            complement(35003..35932)
                     /gene="hlgA"
                     /locus_tag="RFE25_000302"
     CDS             complement(35003..35932)
                     /gene="hlgA"
                     /locus_tag="RFE25_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component gamma-hemolysin HlgAB subunit A"
                     /protein_id="HDU2815404.1"
                     /translation="MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIK
                     RTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMI
                     WPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNY
                     SKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARD
                     YFVPDNQLPPLIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAV
                     DRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK"
     gene            complement(36468..37778)
                     /gene="sbi"
                     /locus_tag="RFE25_000303"
     CDS             complement(36468..37778)
                     /gene="sbi"
                     /locus_tag="RFE25_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin-binding protein Sbi"
                     /protein_id="HDU2815405.1"
                     /translation="MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQ
                     NNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVA
                     QQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKA
                     IKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAI
                     SKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQS
                     PQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEK
                     YDTAKYYYNTYYKYKGAIDQTVLTVLGSGSKSYIQPLKVDDKNGYLAKSYAQVRNYVT
                     ESINTGKVLYTFYQNPTLVKTAIKAQETASSIKNTLSNLLSFWK"
     gene            37873..37977
                     /locus_tag="RFE25_000304"
     CDS             37873..37977
                     /locus_tag="RFE25_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815406.1"
                     /translation="MLTNRLTSVNYVKKRLIQNIQRILSKEVLYGEMQ"
     gene            38598..39464
                     /locus_tag="RFE25_000305"
     CDS             38598..39464
                     /locus_tag="RFE25_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDU2815407.1"
                     /translation="MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADA
                     LNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQN
                     APRLFKEDDVVPNAITIIVSLISGLVMLIVFAVNQRLAKRTKSSSLNSAAKDNLSDSL
                     VSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAY
                     RNDILEVDEVQEVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGI
                     SSVYVHPEPDHL"
     gene            39791..40477
                     /locus_tag="RFE25_000306"
     CDS             39791..40477
                     /locus_tag="RFE25_000306"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDU2815408.1"
                     /translation="MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVR
                     ENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDAR
                     KEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVI
                     PFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTD
                     DLEVIDKYYL"
     gene            complement(40631..40735)
                     /locus_tag="RFE25_000307"
     CDS             complement(40631..40735)
                     /locus_tag="RFE25_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDU2815409.1"
                     /translation="MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK"
     gene            40909..42348
                     /gene="mdeA"
                     /locus_tag="RFE25_000308"
     CDS             40909..42348
                     /gene="mdeA"
                     /locus_tag="RFE25_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdeA"
                     /protein_id="HDU2815410.1"
                     /translation="MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQ
                     VQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVA
                     RIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYLN
                     WRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISE
                     KGFDNPIVLVSMIGGVVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSM
                     IGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMA
                     IVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSM
                     TNTVQQIAGSIGTAALITILSHASKNFSPTMSDYNGMNKIDMMNQIKVDTMLHGYHAG
                     FLFALLITVVSFFCSFMLQGKKKEVDSRQ"
     gene            42469..43248
                     /locus_tag="RFE25_000309"
     CDS             42469..43248
                     /locus_tag="RFE25_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDU2815411.1"
                     /translation="MKRLLFVMIAFVFILAACGNNSSKDKEANKDSKTINVGTEGTYA
                     PFSFHDKDGKLTGYDIDVIKAVAKEEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGI
                     NPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGA
                     DITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSRSAFAF
                     SKKADDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK"
     gene            43229..43948
                     /locus_tag="RFE25_000310"
     CDS             43229..43948
                     /locus_tag="RFE25_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDU2815412.1"
                     /translation="MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLI
                     IALFTALMRISTSKILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQW
                     TLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQA
                     IRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVV
                     CFIISIIQGIYESYIERGYRS"
     gene            43945..44676
                     /locus_tag="RFE25_000311"
     CDS             43945..44676
                     /locus_tag="RFE25_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDU2815413.1"
                     /translation="MIQLNNIHKSFNDVEVIKGIDLSVEQGEVVTLIGRSGSGKTTLL
                     RMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEG
                     LITVKKLKKDEARGKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPKVML
                     FDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQ
                     GAPEEMFNRPKTEELRRFLNVINEE"
     gene            complement(44773..46023)
                     /gene="fmhA"
                     /locus_tag="RFE25_000312"
     CDS             complement(44773..46023)
                     /gene="fmhA"
                     /locus_tag="RFE25_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FemA/FemB family glycyltransferase FmhA"
                     /protein_id="HDU2815414.1"
                     /translation="MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGV
                     KDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCL
                     YVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVL
                     DLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKF
                     RELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSK
                     KNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPK
                     YNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDYSESSEDYGVQQFKKGFNAHVEEY
                     IGDFIKPIKPLLYKVQTYLNHKRR"
     gene            46278..46640
                     /locus_tag="RFE25_000313"
     CDS             46278..46640
                     /locus_tag="RFE25_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4467 domain-containing protein"
                     /protein_id="HDU2815415.1"
                     /translation="MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKK
                     GNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQDFDS
                     RRYYQQHDADYHEENMTN"
     gene            46659..47258
                     /locus_tag="RFE25_000314"
     CDS             46659..47258
                     /locus_tag="RFE25_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDU2815416.1"
                     /translation="MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKC
                     PYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLD
                     FQKQLFAAQQDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDK
                     KIAKDNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK"
     gene            47265..47366
                     /locus_tag="RFE25_000315"
                     /pseudo
     CDS             47265..47366
                     /locus_tag="RFE25_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501155.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            47531..47782
                     /locus_tag="RFE25_000316"
     CDS             47531..47782
                     /locus_tag="RFE25_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDU2815417.1"
                     /translation="MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESD
                     YNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKDIDV"
     gene            47782..48048
                     /locus_tag="RFE25_000317"
     CDS             47782..48048
                     /locus_tag="RFE25_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDU2815418.1"
                     /translation="MARLNITFSPQAFEDYKYFQQNNKKMVKKINELLKSIDRNGALE
                     GIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIKIASCKYHY"
     gene            48083..48154
                     /locus_tag="RFE25_000318"
                     /pseudo
     CDS             48083..48154
                     /locus_tag="RFE25_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501155.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            48343..49890
                     /gene="adcA"
                     /locus_tag="RFE25_000319"
     CDS             48343..49890
                     /gene="adcA"
                     /locus_tag="RFE25_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HDU2815419.1"
                     /translation="MKKKLGMLLLVPAVTLSLAACGNDDGKDKDGKVTIKTTVYPLQS
                     FAEQIGGKHVKVSSIYPAGTDLHSYEPTQKDILSASKSDLFMYTGDNLDPVAKKVAST
                     IKDKDKKRSLEDKLDKAKLLTDQHEHGEEHEHEGHDHEKEEHHHHGGYDPHVWLDPKI
                     NQTFAKEIKDELVKKDPKHKDDYEKNYKKLNDDLKKIDNDMKQVTKDKQGNAVFISHE
                     SIGYLADRYGFVQKGIQNMNAEDPSQKELTKIVKEIRDSNAKYILYEDNVANKVTETI
                     RKETDAKPLKFYNMESLNKEQQKKDNITYQSLMKSNIENIGKALDSGVKVKDDKAESK
                     HDKAISDGYFKDEQVKDRELSDYAGEWQSVYPYLKDGTLDEVMEHKAENDPKKSAKDL
                     KAYYDKGYKTDITNIDIKGNEITFTKDGKKHTGKYEYNGKKTLKYPKGNRGVRFMFKL
                     VDGNDKDLPKFIQFSDHNIAPKKAEHFHIFMGNDNDALLKEMDNWPTYYPSKLNKDQI
                     KEEMLAH"
     gene            50076..50543
                     /locus_tag="RFE25_000320"
     CDS             50076..50543
                     /locus_tag="RFE25_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC domain-containing protein"
                     /protein_id="HDU2815420.1"
                     /translation="MTIKVEDNKIIFSRTIEAPIEKVFDAYTTKELFEKWFHPKGAST
                     KVFRFNAVSGGDAFYAIKTPTMTSYTLAEYKTVKRPYLIEYIDSFATPQGAKDTKMPS
                     MKITLSFSKSNTTKTTVTSTSVFPTKEAAQQVINMGVEQGMNQTLDQLDALLK"
     gene            50627..50809
                     /locus_tag="RFE25_000321"
     CDS             50627..50809
                     /locus_tag="RFE25_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815421.1"
                     /translation="MVERYIKVLILYIFTTLLSSISVTSKCVPNKVIRFILRTAIGYS
                     IFAYGLHYFSNLKKNK"
     gene            51026..51850
                     /locus_tag="RFE25_000322"
     CDS             51026..51850
                     /locus_tag="RFE25_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDU2815422.1"
                     /translation="MIENKKTVEDTYSTGAIVDSISSSVQMKQVMVQQTPGRYMLKAM
                     MAGFLLSIVTVFMFGIKTQFANTHVDGLINLMGAIAFSLGLILVVLTNSELLTSNFMY
                     FTVGWYYKVVSVKKMTWILLYCFLGNILGGFVLFFLMKFAHVMTPEMTQALTALVQKK
                     TVDSTWLNIFTKGIFCNFFINIGIFISMQFKGGLTKAFFIACGVVVFVYMGYEHVVFN
                     AGLYAGMVFFNLDAVSWLHVLKNIVFAFLGNFVGGGIFVGLVYAFLNGKRNRLEQQ"
     gene            52084..52620
                     /locus_tag="RFE25_000323"
     CDS             52084..52620
                     /locus_tag="RFE25_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2815423.1"
                     /translation="MTKTMIRLASEQDAEKLQQLMHEAFTPLRELGIDWPSVNANLDA
                     VKENIDKNTTFVMTIDDEIISTITVRYPWGSVKSISGYPFVWWFATNPEYEGKGYGSQ
                     LLTYVEEAFLRDTLKSAAVTLGTSARLHPWLLKIYEKRGYEIYSEHENDDGDLGVIMR
                     KVLIPERFDETILGQPPF"
     gene            52850..53581
                     /locus_tag="RFE25_000324"
     CDS             52850..53581
                     /locus_tag="RFE25_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin chelatase"
                     /protein_id="HDU2815424.1"
                     /translation="MNGNIIVAHGMRHGRQNQALEAFISELVKDDIHHYDIAFLESEH
                     QDLETVMTTLIQSGVDHFKIVPLLIFSAMHYLKDIPNIVHEMKRRYPDIKVEVSEPLG
                     THPLMRRLIEQRICDALAGDEQQVGVMVVAHGNINGNFTKAHEELQICAQHLQINKPT
                     YARTLYGEISFTHDLESISKRYQKLIVVPLFLYDGRLVNKVKQQMNDMVINTDIHFTP
                     SINFDPILKQIINDRLESLMIPMKI"
     gene            53647..56052
                     /locus_tag="RFE25_000325"
     CDS             53647..56052
                     /locus_tag="RFE25_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDU2815425.1"
                     /translation="MAKQKLVMIGNGMAGIRTIEEILERANDLYDITVIGKEPYPNYN
                     RIMLSNILQNKMTVEETIMNPYEWYEEHGIELITNDPVIEVDRANQSVTTANGIEVSY
                     DKLIFATGSKAFVIPVPGSTLPSVIGWRTIDDTEQMMNIAKTKKKAIVIGGGLLGLEC
                     ARGLLDQGMEVTVLHLAEWLMEMQLDRKAGNMLKADLEKQGMKFEMQANTTEILGEDD
                     VEGVKLADGREIPADLVVMAVGIRPYTEVAKESGLDVNRGIVVNDVMQTSDSNVYAVG
                     ECAEHNGKVYGLVAPLYEQGKVLADHLTNKETNGYKGSTTFTSLKVSGCDLYSAGQIV
                     ENAEIKGIEIFNSVDNNYKKIFLKDGNVVGAVLYGDIDDGSRFYNMMKKGESTEDYTL
                     VSLLTKGGEEASLSIADMADDETICGCNGVDKGTIVNAITENGFTTVEEVTAKTKAGN
                     SCGKCKPQIAQILQHTLGDDFVAAKPAGICGCTDLTRDQIVTQIRAKGLKTSKEVRHV
                     LNFKNKGGCPKCRPAINYYLNMVYPHDHEDERESRFANERYHANIQNDGTFSVIPQMR
                     GGVTDADQLIRLGEVAKKYHVPLVKVTGSQRVGLYGVKKEELPNIWEDLGMRSASAYG
                     KKTRSVKSCVGKEFCRFGTQYTTRLGIRLEKTFEYIDTPHKFKMGVSGCPRSCVESGV
                     KDFGIISVENGFQIYIGGNGGTEVEKAEFLTTVETEDEVIKLCGALMQYYRETGIYAE
                     RTAPWLRRLGFENVKEVLLDPERQNELFERIMDAKKAVEAEPWEAITSNAQARKIFEV
                     EKV"
     gene            56056..56370
                     /gene="nirD"
                     /locus_tag="RFE25_000326"
     CDS             56056..56370
                     /gene="nirD"
                     /locus_tag="RFE25_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HDU2815426.1"
                     /translation="METKEKIKVTTIDELTPLIGKKVIVKGKEVGLFLTESGTIHAIH
                     NICPHKQGPLSEGTVSGEYVFCPLHDQKIDLNTGIVQEPDEGCVDVYEVEVTDGNVYI
                     CL"
     gene            56361..57338
                     /gene="cobA"
                     /locus_tag="RFE25_000327"
     CDS             56361..57338
                     /gene="cobA"
                     /locus_tag="RFE25_000327"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDU2815427.1"
                     /translation="MSVDKYGKVYLIGAGPGNPNYLTKKAERLIREADVILYDRLVNP
                     LILQYANLTTEIIDVGKKPYAKHIQQEKINECIVEAARRYNKVVRLKGGDPAIFGRVQ
                     EEVDTLNNFNIAFEIVPGVTSASAAVATMQTGLTMRAVAKSVTFSTGHFKDSEENEVD
                     VNALVNGGTLAIYMGVKRLGKIIAQIQQYTDIDYPIAIVFQASCFNEFVVKGRLSNIV
                     GKLEHYAIEAKPGICIIGEVVGYTENVSTTSNPTQQFYVVSGSRHDALMLCEHLYDEG
                     YGCLLNPNDTSNGTYHSSQYDYYDAFIKQQENVTYISTDRADANTVLCH"
     gene            57647..61336
                     /locus_tag="RFE25_000328"
     CDS             57647..61336
                     /locus_tag="RFE25_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HDU2815428.1"
                     /translation="MGKFGLNFFKPTEKFNGNWSILESKSREWEKMYRERWSHDKEVR
                     TTHGVNCTGSCSWKVFVKNGVITWENQQTDYPSCGPDMPEYEPRGCPRGASFSWYEYS
                     PLRIKYPYIRGKLWDLWTEALEENYGNRVAAWASIVENEDKAKQYKQARGMGGHVRSN
                     WKDVTEIIAAQLLYTIKKYGPDRIAGFTPIPAMSMISYAAGARFINLLGGEMLSFYDW
                     YADLPPASPQIWGEQTDVPESSDWYNASYIIMWGSNVPLTRTPDAHFMTEVRYKGTKV
                     ISVAPDYAENVKFADNWLAPNPGSDAAIAQAMTHVILQEHYVNQPNERFINYAKQYTD
                     MPFLIMLDEDENGYKAGRFLRASDLGQTTEQGEWKPVIHDAISDSLVVPNGTMGQRWE
                     EDKKWNLKLETEDGSKINPTLSMAEGGYELETIQFPYFDSDGDGIFNRPIPTRQVTLA
                     NGDKVRIATIFDLMASQYGVRRFDHKLESKGYDDAESKYTPAWQEAISGVKQSVVIQV
                     AKEFAQNAIDTEGRSMIIMGAGINHWFNSDTIYRSILNLVMLCGCQGVNGGGWAHYVG
                     QEKCRPIEGWSTVAFAKDWQGPPRLQNGTSWFYFATDQWKYEESNVDRLKSPLAKTED
                     LKHQHPADYNVLAARLGWLPSYPQFNKNSLLFAEEAKDEGIESNEAILKRAINEVKSK
                     QTQFAIEDPDLKKNHPKSLFIWRSNLISSSAKGQEYFMKHLLGTKSGLLATPNEDEKP
                     EEITWREETTGKLDLVVSLDFRMTATPLYSDIVLPAATWYEKHDLSSTDMHPYVHPFN
                     PAIDPLWESRSDWDIYKTLAKAFSEMAKDYLPGTFKDVVTTPLSHDTKQEISTPYGVV
                     KDWSKGEIEAVPGRTMPNFAIVERDYTKIYDKYVTLGPVLEKGKVGAHGVSFGVSEQY
                     EELKSMLGTWSDTNDDSVRANRPRIDTARNVADAILSISSATNGKLSQKSYEDLEEQT
                     GMPLKDISSERAAEKISFLNITSQPREVIPTAVFPGSNKQGRRYSPFTTNIERLVPFR
                     TLTGRQSYYVDHEVFQQFGESLPVYKPTLPPMVFGNRDKKIKGGTDALVLRYLTPHGK
                     WNIHSMYQDNKHMLTLFRGGPTVWISNEDAEKHDIQDNDWLEVYNRNGVVTARAVISH
                     RMPKGTMFMYHAQDKHIQTPGSEITDTRGGSHNAPTRIHLKPTQLVGGYAQISYHFNY
                     YGPIGNQRDLYVAVRKMKEVNWLED"
     gene            61326..62885
                     /gene="narH"
                     /locus_tag="RFE25_000329"
     CDS             61326..62885
                     /gene="narH"
                     /locus_tag="RFE25_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDU2815429.1"
                     /translation="MKIKAQVAMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNV
                     ETKPGVGYPKRWEDQEHYKGGWVLNRKGKLELKSGSRISKIALGKIFYNPDMPLIKDY
                     YEPWNYNYEHLTTAKSGKHSPVARAYSEITGDNIEIEWGPNWEDDLAGGHVTGPKDPN
                     IQKIEEDIKFQFDETFMMYLPRLCEHCLNPSCVASCPSGAMYKRDEDGIVLVDQDACR
                     GWRYCMTGCPYKKVYFNWKTNKAEKCTFCFPRIEAGMPTVCSETCTGRMRYLGVLLYD
                     ADRVHEAASAVDEKGLYEKQLDIFLNPFDEEVIAQAEKDGIGYDWIEAAQNSPIYKLA
                     IEYKLAFPLHPEFRTMPMVWYCPPLSPIMSYFEGKNTTQNPDAIFPAIEEMRLPIEYL
                     ANIFTAGDTEPVKGALQRMAMMRSYMRSQVTQQPFDTSRLERLGITERQTKDMYRLLG
                     LAKYEDRFVIPTSHKETYLDTYHAQGSTGYNYGGEHFGDNCEGCGVAVGSGKTGQEIY
                     NENFYGGIFRD"
     gene            62878..63453
                     /gene="narJ"
                     /locus_tag="RFE25_000330"
     CDS             62878..63453
                     /gene="narJ"
                     /locus_tag="RFE25_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDU2815430.1"
                     /translation="MINFDNFKKYQESFGYMAQQLCFPEKLTFHPKTFEETISKDHPA
                     YEDLVAFRNVMMTFSLSEIKAIYTDTFDFTKKAPLYMTYNKFDTQKERGQMLAKLKVL
                     YEMFGLEMVDNELSDYLPLMLQFLQVAEWRNDPRAEENIQLIIMIIEDGTYVMANALG
                     EDNNPYAYVIQALRKTLKLCLTSPKGVKHHA"
     gene            63446..64123
                     /gene="narI"
                     /locus_tag="RFE25_000331"
     CDS             63446..64123
                     /gene="narI"
                     /locus_tag="RFE25_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDU2815431.1"
                     /translation="MLNQFLWVIFPYLCLVVFVAGHIARYRYDKFSWTAKSSELIERK
                     RLMWGSLLFHLGIIPVFFGHVVGLLIPKSWMDAVGVSEHLYHIGAVYIGSIFGIITLI
                     GMFLLTARRVTTKSIRRLSSASDIFVNFLLLLIVFMGCYATLVTNIQHPDFNYRTSLS
                     IWFRQLFMLKPDASLMSGVPIAFKMHILLGFTIMACWPFTRLVHVWSVPLTYINRRYI
                     IYRKNKV"
     gene            64143..64595
                     /gene="nreA"
                     /locus_tag="RFE25_000332"
     CDS             64143..64595
                     /gene="nreA"
                     /locus_tag="RFE25_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate respiration regulation accessory nitrate
                     sensor NreA"
                     /protein_id="HDU2815432.1"
                     /translation="MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKW
                     HYVSGNKNNRFKLIILRKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESL
                     TAVLAVPLWYKNQVYGVLLFGQRDGRPLPKIFDNDDIQRKFGIFNDDK"
     gene            64619..65653
                     /gene="nreB"
                     /locus_tag="RFE25_000333"
     CDS             64619..65653
                     /gene="nreB"
                     /locus_tag="RFE25_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501138.1"
                     /note="Involved in the regulation of the the nitrate
                     reductase operon narGHJI; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate respiration regulation sensor histidine
                     kinase NreB"
                     /protein_id="HDU2815433.1"
                     /translation="MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDIL
                     SEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLESMQVQATNFQVFMKTKDQKVMPF
                     TATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDS
                     VIQEMLNVDVQLRLLKYQEDTTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLG
                     LEAAFKSYFKQFEENYGIKIIYTSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNE
                     INVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAELVSGSVNIETKIGE
                     GTNVTLNIPI"
     gene            65676..66329
                     /gene="nreC"
                     /locus_tag="RFE25_000334"
     CDS             65676..66329
                     /gene="nreC"
                     /locus_tag="RFE25_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002464689.1"
                     /note="Involved in the regulation of the the nitrate
                     reductase operon narGHJI; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate respiration regulation response
                     regulator NreC"
                     /protein_id="HDU2815434.1"
                     /translation="MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVME
                     YKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYI
                     LKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTTDPFKILSKREL
                     EILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF"
     gene            complement(66587..67327)
                     /locus_tag="RFE25_000335"
     CDS             complement(66587..67327)
                     /locus_tag="RFE25_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDU2815435.1"
                     /translation="MAYTYTLKDIIEITGVTKRTLHYYDEIGLLVPDKNDKNYRVYKQ
                     QDLEKLQKILILKSFDFDIAKIKQYISYDNEQLRKLLSEQISKLDKKISDLQLIRRSV
                     CEFIKGLSLIDTSILNKTLQSQYDKEASIKYGHTKAYQSFIRRKDSLQSQDIRHKLTT
                     IFNKFNHMSLSHYPIQDCSDLVFEWKAFMNTIADFDDETLCCIAKTYEDDTRFKDYFN
                     SYDNQNLASYISEAVNYFLSNVNKSDNF"
     gene            complement(67306..68220)
                     /locus_tag="RFE25_000336"
     CDS             complement(67306..68220)
                     /locus_tag="RFE25_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDU2815436.1"
                     /translation="MYKINIIRSDSVYKNILKAPINDRDSIFTKEILVPFKKKFEVQH
                     MPIYNDDKQTMSAIQFLDAFQISPKDLRMSDQMSIQYLNNDFWSNCEKYLKVAIDQFS
                     NYSISSQVSNYHFTVLLGDSQKPLMYLNKNRGGDGGIPGYIMIYLVPSTSTINSMKSL
                     IAHEVNHNMRYRYIDWDGGSLIELIIAEGLAENYVESLYGKAHIGPWVTNTNWSRDNV
                     KIKNTIYNHLHLKHIFESMPYLYGDDINKLQGRPIVGLSHAAGYACGYHLVKYFLQKT
                     NIPIEVATTLPAQKIINEVTEFWHTHTL"
     gene            68589..69758
                     /locus_tag="RFE25_000337"
     CDS             68589..69758
                     /locus_tag="RFE25_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NarK/NasA family nitrate transporter"
                     /protein_id="HDU2815437.1"
                     /translation="MYKTKGGFQLTLQTLSLVVGFMAWSIIAPLMPFIKQDVNVTEGQ
                     ISIILAIPVILGSVLRVPFGYLTNIVGAKWVFFTSFIVLLFPIFFLSQAQTPGMLMAS
                     GFFLGVGGAIFSVGVTSVPKYFPKEKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQ
                     TTVRSYLIIIALFALIMFIFGDTQERKIKVPLMAQMKTLSKNYKLYYLSYWYFITFGA
                     FVAFGIFLPNYLVNHFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDF
                     VIMIIGAVILGISDHIALFTVGCLTISICAGIGNGLIFKLVPSYFSNEAGSANGIVSM
                     MGGLGGFFPPLVITYVANLTGSSHLAFIFLAVFGCIALFTMRHLYQKEYGSLKHS"
     gene            complement(69865..70293)
                     /locus_tag="RFE25_000338"
     CDS             complement(69865..70293)
                     /locus_tag="RFE25_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HDU2815438.1"
                     /translation="MILNFNQFENQNFFNGNPSDTFKDLGKQVFNYFSTPSFVTNIYE
                     TDELYYLEAELAGVNKEDISIDFNNNTLTIQATRSAKYKSEQLILDERNFESLMRQFD
                     FEAVDKQHITASFENGLLTITLPKIKPSNETTSSTSIPIS"
     gene            complement(70509..70955)
                     /locus_tag="RFE25_000339"
     CDS             complement(70509..70955)
                     /locus_tag="RFE25_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDU2815439.1"
                     /translation="MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVL
                     MAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQG
                     KAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDRK"
     gene            71352..71717
                     /locus_tag="RFE25_000340"
     CDS             71352..71717
                     /locus_tag="RFE25_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDU2815440.1"
                     /translation="MKKKKNAIKVIIILFISLIVAVAFFFGLKTYQGHKNIQLIDSYL
                     EEKNLKDKIKSEKTEYSAKKGLFYKEVTFKDEPGVTYVVQPISTNKGLFVEGFDTETK
                     KSLKTAKHKYFNQNYKPSK"
     gene            71899..73176
                     /locus_tag="RFE25_000341"
     CDS             71899..73176
                     /locus_tag="RFE25_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDU2815441.1"
                     /translation="MALFKRKISLPMQVVIALVLGVVVGLLLYGQENVANYIKPFGDV
                     FLNLIKMIVIPVVFCSLALSISNVGESKTVGRYGWKTILYFEIITTIAIGLGIIFGNL
                     FKPGAGLDPTKLPKGDISKYQSTAHAAEQSTYGNHFIDTIVHIIPTNFFEALNKGELL
                     PIIFFAVFFGLGLAAVGKKAEPVKEFLSGSLEAVFWMINKILKLAPLGVFAFICTTII
                     TFGASALLPLLKLVLVVVFAMVFFVFAILGLVAWMCGINIMNIIRILKSELLLAFSTS
                     SSEAVLPVMMKKMENFGSPKEITSFVIPIGYTFNLDGSALYQSIAALFVAQMYGMHLT
                     LSEQIVLMLTLMITSKGMAAVPGTSIVVLLTTLGAMGLPAQGLALIIGVDRILDMVRT
                     CVNVIGNALSTIVIAKWENVYDKAKGQEYLKSI"
     gene            complement(73555..73911)
                     /locus_tag="RFE25_000342"
     CDS             complement(73555..73911)
                     /locus_tag="RFE25_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4889 domain-containing protein"
                     /protein_id="HDU2815442.1"
                     /translation="MKKKKGFGLGISLIAIMLIVCIVLVIMMMTGGKKDTYYGIMKDN
                     TTIEKMISEKDESIEKNVKLPSDSDVKVKKGDFVIVYKLADSDKIVKVKKVDHDDVPH
                     GLMMKIHDMGKMHMKH"
     gene            complement(74175..74597)
                     /locus_tag="RFE25_000343"
     CDS             complement(74175..74597)
                     /locus_tag="RFE25_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDU2815443.1"
                     /translation="MSNSQAIQAIENVLATSKVGVLSTAYNNKPNSRYMVFYNDGLTL
                     YTKTNIHSAKVKEIKDNPAAYVLLGYNDTTNRSFVEMEATIEVVTDQKVIDWLWETQD
                     KSFFSSKEDPELCVLKVTPQSVKLMNDKSLDTPIKIDL"
     gene            complement(74668..>76722)
                     /gene="rsp"
                     /locus_tag="RFE25_000344"
     CDS             complement(74668..>76722)
                     /gene="rsp"
                     /locus_tag="RFE25_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator Rsp"
                     /protein_id="HDU2815444.1"
                     /translation="NINNIMVLFSLTSKLNITINGETKDVSNYIILINHGDIYNINHG
                     ENIIELMIPVFYFYQQDDDFFNGYLDRHLLQSSNYIKSLIADLISTPTSSSLMGKNIG
                     QSIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNIDAHLSLKDIAMHCNISE
                     SYCSNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTVSELAGFNSHTNFANQFK
                     NYLHFSPKQFRSLVSKITEPPQIHFQQDNVSQFTELISTIDLTAQLATNTTDIHIDDF
                     NPKDRSQRAKVFVRFSNFNELFQFIFNEYYDINFEHLPKPVVFIDDIHDIEISQTNYN
                     LLNRCFEKLFEKNIGLAIAIKSTQQFETMKQLILTFLQGNQDYKTSKKLVKFMLVFCS
                     NSMTAEEIHLCHLKIKNKNKEIKYSVTVDGFLETYSTVEQVYDVMQRLKFHYYFIDIE
                     NSKTATHLITKNQHYHQTDTHFEQYKKFILDSGISSTQFVYNNLSVSGFKYTNDGKNP
                     IQLSDIVYHLIALLRYGGGISYQLLDDHSNYISLYNKYGSPLPLMHLYKMFRPFVNED
                     IEITNNYVLSRKDNNYHFLLFNKINDRYMSDVKQDFIFHNELPQDSLMIIKTLNHEHG
                     SIQHLLPISDQLVYIEKEILDELDKTNYPKTELAVQEETGRTFELKLNHDEVKYICFK
                     PS"
BASE COUNT        26111 a        10903 c        14275 g        25433 t
ORIGIN      
        1 agagttagaa gctaagttcg aagaaatgcc acagttagag tcttcatttt ataaattaac
       61 gccaggcaga caacatcaat atatatatca tattggacaa gctaaacgca gtgaaacaag
      121 acaaaagcgt gttgaaaagt atattaacca aatactagaa ggtaaaggga tgcatgataa
      181 gtaattaatg agtaaagcat accggttata caacaacata caagatgaca cgaaacaacc
      241 aatggctcat gctgttggtt gtttttttag gtgtgtctgt catgggcaac actttgacgt
      301 tggaattccg ttacaggctt gggagtagaa aatgttagca aaaggcaagg gtgtctacaa
      361 tgaatgatga agatattaaa atataaggat gactttgtga gtggcggatg ggcggttgtc
      421 cgtctgtaac aatggatgcg tgtgcattat tacaaaaatt cgacttttgt aataatattt
      481 cacattttcg acactttttt gctataaaac aaccaattga gcgataataa attcgctttt
      541 aaaaaatatg agttatctat ttagttgcca aagataaaat aataatgttt aataacatca
      601 tatagagtat gttagtttta aatgtcgaat atacgaatgt gcaaacaaag taatcggtag
      661 aaattcaaca tacatagcgc cgtttactgt taagtattca cattacagat gaaaaatata
      721 aaattctaca taatcaagac catgatgtgt acttgtttaa cttatgactc tatttgttta
      781 acaattgcga taatggtctt tttattttat gcgtatcatt cgtcatattt tttatgagga
      841 aggagaaatg attatgttaa gtattaagca tttaacgaaa atttattctg gtaataaaaa
      901 ggcagtagat gacatctctt tagatattca atctggggaa tttatcgcat ttattggaac
      961 cagtggaagt ggtaaaacaa ctgctttaag aatgataaac cgtatgattg aagcgacaga
     1021 aggacaaatt gaaattgatg gtaaagatgt tcggagtatg aatcctgtcg aattacgtag
     1081 aaatattggt tatgttattc aacaaattgg gttaatgcct catatgacga ttaaagagaa
     1141 tattgtattg gtacccaaat tgttgaaatg gactaaagaa gaaaaggata aacgtgcaaa
     1201 ggaattaatt aaacttgtgg atttaccgga gtcattttta gagcgttatc cagcagaact
     1261 atcaggtggg caacaacaac gtatcggtgt cgtaagagca cttgcggccg aacaagatat
     1321 tattttaatg gatgaacctt ttggtgcatt ggatcctatt acgagagata cgttacaaga
     1381 tttagttaaa acgttacaac gaaaattagg caagacgttt atctttgtaa cacatgatat
     1441 ggatgaagcg attaaattag cagacaaaat ttgtattatg tcagaaggta aggtggtgca
     1501 atttgataca ccagacaata ttttaagaca tcccgcaaat gattttgtac gtgattttat
     1561 aggacaaaat agactgattc aagaccgtcc caatgacaag actgtagaag gtgtaatgat
     1621 taaaccaatc acgatacagg cagatgcaac gcttaatgat gctgttcata ttatgagaca
     1681 aaagcgtgtt gatactattt ttgtagtaga tagtaataac catttactag gtttcttaga
     1741 cattgaagat ataaatcaag gtatacgtgg acacaaaagt ttacgagaca ccatgcaaca
     1801 acatatttat accgttcaaa ttgattctaa attacaagat tctgtacgta cgattttaaa
     1861 aagaaacgtt aggaatgtac ctgtcgtaga tgataagcaa cgtttagtag gactgattac
     1921 gcgtgccaat gttgttgaca ttgtatatga cacgatttgg ggcgatagtg aggatgcagt
     1981 gcaaacagaa catgtggggg aagacactgt gtcctcaaaa atgcatgagc aacacactac
     2041 taatgtcaaa gtacgtgaca taggagatga taaatcatga ttgagttcct acatgaacat
     2101 ggtggacagt tgatgtcgaa aacactggaa catttttata tttctatagt ggcattatta
     2161 cttgccatca ttgttgcagt acctataggc attttattat caaaaacaaa gcgaactgcc
     2221 aatattgtat taactgtggc aggtgtctta caaactattc caacactagc tgtacttgct
     2281 attatgatac cgatttttgg tgttggtaaa acgcctgcaa ttgtagcgct atttatttat
     2341 gtattattac ctattttaaa taacacggta ctcggtgttc aaaatattga tagcaacatt
     2401 aaagaagctg gaaaaagtat gggaatgaca caatttcaat tgatgaagga tgttgaattg
     2461 ccgttagcat tgccgcttat cattggtggc attcgtttgt catctgtgta tgtaattagt
     2521 tgggctacac ttgcaagtta tgtaggtgcg ggtggattag gtgatttcat tttcaatggt
     2581 ttaaatttat atgatccact gatgattgta actgcaacgg tactcgttac tgcactagca
     2641 ttaggtgttg atgccttatt agctttagtt gaaaaatggg tagttcccaa aggcttaaaa
     2701 gtatctggat aattaggagg ctaagataat gaagaaaatt aaatatatac ttgtcgtgtt
     2761 tgtcttatcg cttaccgtat tatctggatg tagtttgccc ggactaggta gtaagagcac
     2821 gaaaaatgat gtcaaaatta cagcattatc aacaagcgaa tcgcaaatta tttcacatat
     2881 gttacggttg ttaatagagc atgatacaca tggtaagata aagccaacat tagtaaataa
     2941 tttagggtca agtacgattc aacataatgc cttaattaat ggggatgcta atatatcagg
     3001 tgttagatat aatggcacag atttaacggg agctttgaag gaagcaccaa ttaaagatcc
     3061 taagaaagca atgatagcca cacaacaagg atttaaaaag aaatttgatc aaacgttttt
     3121 tgattcgtat ggttttgcga atacgtatgc attcatggta acgaaggaaa ctgctaaaaa
     3181 atatcattta gagacagttt cagatttagc aaagcatagt aaagatttac gtttaggtat
     3241 ggatagttca tggatgaatc gtaaaggcga tggctatgaa ggatttaaaa aagagtatgg
     3301 ttttgacttt ggtacagtga gaccaatgca aataggtcta gtctacgacg cattaaacac
     3361 agagaagtta gacgttgcat taggttattc tacagatggt cgaattgccg cgtatgattt
     3421 gaaagtactt aaagatgata aacaattttt cccaccttat gctgcgagtg ctgttgcaac
     3481 aaatgaatta ttacggcaac acccagaact taaaacgacg attaataagt tgacaggaaa
     3541 gatttcgact tcagagatgc aacgcttgaa ttatgaagcg gatggtaaag gtaaagaacc
     3601 tgctgtcgtc gcagaagaat ttttgaaaaa acaccactat tttgataaac agaaaggtgg
     3661 tcataagtaa tggaaggtaa tttattacag caattattca attattatgt tacgaacttt
     3721 ggttatctat gggatttatt tttcaaacac ttattaatgt ctgtctatgg tgtgctgttt
     3781 gcagctttaa ttggtattcc attgggaatc ttgcttgcaa gatacacaaa actttctgga
     3841 tttgtaatta caattgcaaa tataattcaa acagttccag tcattgcaat gttagctatt
     3901 ttaatgttag tcatgggctt aggttcagaa acagtagttt taacagtgtt tttatatgcg
     3961 ttacttccaa ttataaaaaa cacttatact ggtatagcta gtgttgatgc gaatattaag
     4021 gatgctggca aaggtatggg aatgacacgc aatcaagtgc tacgaatgat tgaattaccg
     4081 ttatctgttt cggttattat cggtggcatt cgtattgcct tggttgttgc gataggtgtt
     4141 gttgccgttg gatcatttat aggagcacct acgcttggtg acattgtgat tcgtggtaca
     4201 aatgcgacgg atggcacaac gtttatttta gcaggtgcga ttccgattgc tatcattgca
     4261 atcgtcattg atgtactatt aagattttta gaaaaacgat tagacccaac aacacgacat
     4321 cgtaaaaatc aatctaatca tcggccgcaa agtattaata tgtaatagta gaagatgttt
     4381 ataatttagc gatttcgttt catgatttat aaaaaatgag gctactcaag gagctcaaat
     4441 aatctttgag tagccttttt ataggttgtg tttgtatgcg tttacactaa aatagcaatt
     4501 attatcatga aagtttttgg ataaaaagcg ttaattattg taaaaatgct aaaaaatgag
     4561 atgttttatt tataattttc tgcaaattta tgatattgtt tcttaatata tcatattaaa
     4621 aatttgtttt tcttaaacat aggaggctta tctaattcat ggacacatca aaacaattta
     4681 gaggtgacaa ccgattgctt ttgggtatcg ttttaggggt tattaccttt tggctattcg
     4741 cgcagtcact tgttaatctt gttgtcccat tacaatcaac atatagtagt gacgttggaa
     4801 cgataaatat cgctgttagc ttatctgcct tatttgctgg tttgtttatc gtaggtgctg
     4861 gtgatgttgc tgataaattt ggtcgcgtca aaattactta tgtaggattg atattaaatg
     4921 ttgtaggttc attactcatc atcattacac ctttgccagc atttttaatt ataggtagaa
     4981 taattcaagg tttgtctgca gcatgtatta tgccatccac acttgctatt attaacgaat
     5041 attatattgg tacaagaaga caacgtgcct taagctattg gtctattggt tcttggggtg
     5101 gtagtggtat ttgtacgttg tttggtggct taatggctac atatataggt tggcgttcaa
     5161 tatttgttgt ttcaattcta ttaacattat tagcaatgta cttaatcaaa catgcacctg
     5221 agactaaagc agaaccaatc aaaggtatga aagcagaagc taaaaagttt gacgttattg
     5281 gtttagtcat tttagtagtg acgatgttaa gtttaaatgt aatcatcaca cagacgtctc
     5341 attttggttt agtttcaccg ttaattctag gtttaattgt tgtgtttatc tgttcattag
     5401 ttggttttgt atattacgaa aataaaataa agcatccact tgttgatttt tcaattttta
     5461 aaaatagagg atacagtggt gcaactattt caaacttctt attaaatggt gtagcaggtg
     5521 gtgcacttat cgttattaac acgtattatc aacaacaatt aggatttaat tcttcgcaaa
     5581 cgggttatat ttcattaacg tatttaatag cagtgttgtc aatgattcgt gtaggtgaaa
     5641 agattttatc tcaacatggt ccgaagcgcc cactattact aggaagtggc tttacagtga
     5701 ttgggttaat cttattgtcg ttaacatttt taccagaagt gtggtatatc atatctagta
     5761 tagttggata tttattgttt ggtactggtt taggattata tgctacacca tcaactgata
     5821 cagcagttgc tagtgcgcca gatgataagt cgggtgttgc ttcaggcgta tataaaatgg
     5881 cgtcatcatt aggaaatgca tttggagtag cagtatctgg tacagtttat actgtgttag
     5941 cagctaattt aaatttgaac ttaggtggtt tcacaggtat gatgtttaat gccttgctag
     6001 caattgttgc atttttagtc attttactat tagttcctaa aaatcaaacg aatttgtaaa
     6061 accgaaatga aagcaagtta ttatgtaggg attttaaagg aaattttgtg aaagtaagtt
     6121 tatcatacac acttaatgtt acgtattgac gtttaatgtt aggtgtgttc ttttatagac
     6181 gataaaagct gtgtgcatat taagcgaatg attttcaaat tgacgctaat atgcgaaagt
     6241 agtattttta aaatgaacaa caacgatgaa gaggggttta taggatgaaa attgcaattg
     6301 ctggatcggg tgcattaggt agtggctttg gtgccaaact atttcaagca ggatatgatg
     6361 tcacacttat tgacggatat acatctcatg ttgaagcggt taagcaacat ggattaaata
     6421 taacgattaa tggagaggca ttcgagttaa acattccgat gtatcatttt aatgatcaac
     6481 gggacgaaag catttacgat gttgtctttc tatttccaaa gtctatgcaa ttaaaagaag
     6541 tgatggaaga tatgaagcca catattgata atgaaacgat cgtcgtatgt acgatgaatg
     6601 gtctgaagca tgaagaagtc attgcgcagt atgttgctca atcacaaatt gtcagaggtg
     6661 ttacgacttg gacggcaggt cttgaaagcc ctggacacag tcatttactt ggtagtggac
     6721 cagttgaaat aggtgaacta gtggatgaag gtaaagaaaa tgttataaaa gttgctgatt
     6781 tacttaacga agcggaattg aatggtgtca ttagtaaaga tttataccaa tcgatttgga
     6841 aaaagatttg tgttaatggt acggcaaatg cattaagcac agtgttggag tgtaatatgg
     6901 catcactgaa tgaaagtagt tatgcgaagt gtttgattta taaattaacg caagaaatag
     6961 tgcatgtagc gacgattgat aatgttcatt taaatgttga tgaagtattt gaatatttag
     7021 ttgatttaaa tgaaaaagtt ggtgcgcatt atccatccat gtatcaagat ttaattgtta
     7081 ataatagaaa aactgaaatt gattatatta atggcgcagt tgcaacattg ggtaaacaac
     7141 gtcatattga agcgccagtc aatcgcttta ttactgattt aattcatact aaagaaagtc
     7201 agcgacacgc acaggattaa ttggtgtttt aggtatgatt acaaggaaat gacaatcacg
     7261 tgatattacg gtcattatta agattgaaat gtaataaata aagaacagca gtaaggtact
     7321 ttcaaattga aatgatcttg gtgctgtttt tcttgattga tcttcgtcat aattcagatt
     7381 tgtcataggt ctacgacata ctattagtat ttactagaca gtttttacga cgacactttg
     7441 aaaaattttg aggcaaatca tttggaagtc tcacgtgaat tttgtaaact catcaagcaa
     7501 gtaattatat taaaaagaca aatagagaaa aggtgtttat aatgagtaaa atttttgtaa
     7561 ctggtgcaac gggccttatt ggcattaaat tagttcaaag actaaaagaa gaggggcatg
     7621 aggttgctgg ttttactaca tctgagaatg gtcaacaaaa gctagctgct attaatgtaa
     7681 aagcatatat tggtgatata ttaaaagctg atactattga tcaagcgtta gcagatttta
     7741 aaccagaaat cattatcaac caaattacgg atttaaaaaa tgttgatatg gcagcaaata
     7801 cgaaagtacg tattgaaggt tctaaaaact taattgatgc ggcgaaaaag catgacgtta
     7861 agaaagtaat tgcccaaagt attgccttta tgtatgaacc tggcgaagga ttagcaaatg
     7921 aggaaacttc acttgatttt aactcaactg gtgatagaaa agtaacggtt gatggtgtgg
     7981 ttggtctaga agaagaaacg gctcgtatgg atgaatacgt tgttttacgt tttggttggt
     8041 tatatggccc aggtacttgg tacggaaaag atggcatgat ttataatcaa tttatggatg
     8101 gtcaagtgac actttcagat ggcgtaacat catttgtgca tcttgatgat gcagttgaaa
     8161 catctattca agctattcat tttgaaaatg gtatctataa tgtagcagat gatgcacctg
     8221 ttaaaggttc tgaatttgca gaatggtata aagaacaact tggtgttgaa ccaaatattg
     8281 atattcaacc tgcacaacca tttgaacgtg gcgtaagcaa tgagaagttt aaagcgcaag
     8341 gtggtactct gatttataaa acttggaaag acggcatgaa tccaattaaa taataattta
     8401 tccgtttaat atacaaagaa taaagacttg gtcgaatcgt ggatgatata ttatcaaacg
     8461 cacggctcga acaagtcttt tttattatgt cttcgttatc tttgtatgaa ggaataacag
     8521 aattacaatt aatgtactga ataatgcaat taatgttgtg attagtgcta atttaatttc
     8581 tattggtagc caagtcagta caaaagacca attattgcta ccgagaatga gatatggtaa
     8641 tgcatataat atgagcgcta tagcgataca taaacataaa gttagccaac tcaatacagc
     8701 aatccgtttt gatctacgca aaagaatttg accatggcgc atttgccaag cacgataagc
     8761 tgagaatata aatgctaata aaataagtgt tgtcatcaaa acggtaacaa tattaaattg
     8821 gtctttatat tgattgagta tagacgcaac cgtcgaatat cgcttgtgat ttacaatttg
     8881 tgtattaaga tgctcaacta atttgggtac atattccgaa tttagatttg caagcacaac
     8941 aattccataa ttttgttttg gatttagtaa aataaatgat gaaaagttat cgagcgttcc
     9001 tgaatgaaac actaaatgtt catcattatt ggtaaaccag cccgaagcat atgcattggc
     9061 attaggttca ccaattgttg atgataaatt tttatgtgat tgttgaacta atgatttgta
     9121 tttatcaggt ggattaagtt ggaattttat ccaatgttcc aaatcttcag ttgatgtcat
     9181 catatatgct gatggtgtat cccaaaggtt aaattcaggt ttagagacga caggtgtcga
     9241 accttgtaat tcgtagccaa tagcatcatg ttttgatttg ttattggttt gtttgaatga
     9301 tgtatgtgtc atatgcaaag gcttgagcca tgaatttgta atatattttg tataggattg
     9361 cttcgtaacg ttttggataa ttaaacctaa taaatcatag ttcatatttg agtattcaaa
     9421 ttcttctccg ggcttatgat gtaattcatc acccataatt gcacgggtta catcatttaa
     9481 acgattattt ttatttgtta cggcgtcttc gcttgtaata tcactaggta taccacttgt
     9541 ttgagccaaa agttgcttaa tcgtaatagt ttcattttga ccattatagt tcattttaaa
     9601 atgaggcaca tgtttggata cgtcatcatt taagtttaat cgaccttctt gagctaattt
     9661 taaaattgca agacctgtga aagctttagt attagaagca atttcatact ttgttgtggg
     9721 agaagctttg acttttttat caacatcttg ataaccataa cctttattta aaaaaacttt
     9781 gccatttttt actattaaaa ttgatgctcc aggaatgtgt cccttttgta aatcatgctc
     9841 gataatttta tctatttgtt gttgcgaatc attggttaac cgtgtcttcg tattgctatt
     9901 taatgttata tatatagcaa ttgaaatggc gactaaaatg ataatagaaa tggatagaaa
     9961 atacagtttt ttagtagtca taaacgttcc tttttatatg ttaaatttac ttaagtgcct
    10021 aatgagattt attttattat accagttcta ttgaataaat taattaaaga ggtatattta
    10081 ccattatttt tgacacctta tatgttaata ggtgtataat tacataaaaa atattaatta
    10141 actctctata ctttttggaa agataggcgt atagtgatat ccatcaaaaa ctataaaaag
    10201 gaataggaga ttatgttcaa tcaatttaaa agacttatta tagggcaacc taaaaaaaac
    10261 agagaactaa aagacgaaaa gatatcgaag tttaaagggt tagcgattct ttcgtcggat
    10321 gcattatctt cagtggctta cggtcccgaa caaatactga ttacattatc agtagtgggt
    10381 gcagttgcaa cttggtatac tttaccgatt gcaggtgctg ttctgatctt attagctgct
    10441 ttaattatgt cttataggca aattatttat gcatatccta aaggtggcgg cgcgtatatg
    10501 gtgtccaaga ccaatttagg agaaaaatgg ggattgcttg caggaggctc attattagtc
    10561 gattacatac tgactgtcgc tgttagtata tcatctggtg ctgatgcatt tgttgctgca
    10621 ttcccaagtt tatatgggca taaagtactg attgcatgtt tacttgtact ttttatttta
    10681 atattaaatt tacgtggttt aactgaatct gccaccgtat tatcctatcc agtatatctt
    10741 ttcattatag ggttagtgat attaatattt ataggtactt tccgtgtggc gacaggagat
    10801 attcaaccac atatgcatgc atcagtagga actgcggttc ctggagtaac attattcttg
    10861 ctattaaaag ctttttcatc aggggcttca tcattaacag gtgttgaagc tatttcaaat
    10921 gcggtaacca attttagaga accaagtgct aataatgctg taaaaacgtt aattgctatg
    10981 ggttcaattt tagcgttttt attagttggt atcgttggtt tagcatatgt ttatggaatt
    11041 atgccacaaa cggaaacgac agttttatca caattagcta tgcaaatatt tggtgataat
    11101 gctgccttct attttgtaca ggcaacgacc gtgatgattt tggtattagc agccaacact
    11161 ggatttacag cttttccgat gttagcggct tcaatgtcta aagataaata tatgcctaga
    11221 atgtttactg ttagaggtga tcgcttaggc tactctaact caattattat tttaggtgta
    11281 ttagccatta ttttaattat tgtatttgat ggtatgactg aagatttaat tccattgtat
    11341 gctgttggtg tatttattcc atttacacta gcacaattcg gtatggttat taaatggatt
    11401 catgaacgtc ctaagaattg gttaagtaag ttgtctgtga acttactagg tggtatcgtg
    11461 acatttattg tttttatgat tttactcata actaaattta gccaagtatg gccgatactt
    11521 attttcttgc cgttcgtggt gattttcttc ttgaaaatta acaaacatta tcgagatatc
    11581 gcagaacaat tacgttctga cattgatgtt cttaatgtgg acgtggtaga tcgtaattta
    11641 gcaattgtgc cgataacaag tattacaaca gcagttgata agtctattta ttacgcacaa
    11701 atgcttgcga ataatgatgt catagcagta catgtatcat ttggagatga agatgaaaaa
    11761 gcattccaag agaaatggaa acgtcatttc ccagatgtaa gattagttat tttacattcg
    11821 gaatatcgca gtattatacg accaatttca cgttttatcg ataagattaa tcgtaaagca
    11881 aacgatcaaa actatatgat tacagtagtg ataccagaat ttattactaa gaaacgttgg
    11941 cataatttat tacacaatca aactagtttg cgtatgaaat tgtatttaat ttatcaaaag
    12001 aatgttaacg tatgtacaat tccatttaaa cttaaaaaat agattctata atcaaatcgg
    12061 attgatgaaa ggttatttac ttttcatcaa tccgattttt tgatgttgaa tataaaaacc
    12121 ccgtacatat gagatgataa tgactttgtc tcatatgtat ggggggtatt gttatgtctt
    12181 gcttaatgtt tggactgtaa agacaagaca atttcgttgt aattgatatt ttctcgaatt
    12241 tgagctgcaa cgatattgtt gattttattt ttgcgaatta attcatctaa aaggtgacgt
    12301 tgtaagtaca atgcttccaa tttgtggtta tggaacatag cttgcggtat gatttgattg
    12361 ctgttttctt gacgttcttt tcgacgttgt gcacgccact ttaatgagcg actcatatca
    12421 tagtaatgat taatgactaa gctaacctca agtacatttg tactattttg ttcttctttt
    12481 aagcgtaaaa taatattgtg attcacaata cgcataattt tttgaacatc tttgaatgaa
    12541 ttttcaaatt cttgcttctt agattctttg tttaaggctt tgtagtgctt catcgcttta
    12601 agtctaagcc ataacatctt gaagaagttt gcaaattttt caacaaatga tgcagtacgg
    12661 tgtgtctctg ttaattcgac aatattgcgg taattattaa tatcctgata cgttgcctta
    12721 cctttatcaa ttaaacgctc aagtgtagat gtttcgatta cttttgcaat atcttctaaa
    12781 cgtttgagtt cttttgtatt ttgattatta ggttctgaat ttaataaaaa taacaattct
    12841 ccatagtatt ggtttaatac tgggcgataa tttgtatcgt ttttgtcttt tttactttcg
    12901 tttttaaaat gctgtatcac tttttgaaca atgaaaattt tggcagattg ataagtcata
    12961 cctttaaaag tagtatcttc ggcagatggt gtaattaaag gtaaaacaat ttgcgctaag
    13021 attaaactaa ttaataccat gaaagatgca ataaacaata aatcattacg gtattcgaat
    13081 gcttgtcctt ttgtaatgat aaatggtaat gtaagtgcca ttgaaagtga aattgtaccg
    13141 tgaataccac acatcgtcat aataaatgcg taacgcacac gagaaggtgg tgtttcatgt
    13201 gaatcatgtt cttcgtctag ataagattgt atatttttcg ggaaataaaa atctttgtac
    13261 cagaaataaa cccaaacaaa tcgacatgca taaattgcaa tagcgattaa tatagtgatc
    13321 actattaaaa atgaaaagtt gtcaggctct gtttggaaaa tatctatgac tacagtagga
    13381 atcataaaac ctaatacaac aaatacaaaa ccatttaagg cataactaaa tgtgttccaa
    13441 atttgatggt aattcatttg tagttccgtt tgtgctctaa ttaaacggtc gcgttctaaa
    13501 ccatggatta gacctgcgat tacaactgca atgatacctg aagcatgaac ttcttctgct
    13561 aaaaagtata cgacaaaagg agttaataat tgaataaaag ttaaggtatt gttatctttt
    13621 aaacctttat tagcggttaa gtctatacgt attctaacga caacgaatcc aataattgca
    13681 ccaataagta cacctagtat tgttgaaatg ataaattgtt caacagcttg gaataatgaa
    13741 aaggtaccag ttactaatgc agtaacagca attttaaatg aaatgatacc tgctgcatca
    13801 ttgagtaaag attcaccttc taaaatcgtc atagaacctt taggtaataa ttttccgcgt
    13861 gtaatagcag atactgctac tgcatcagta ggacataaaa ttgctgctat tgcaaaagcg
    13921 gctggcattg gtaaggcagg ccaaatccaa tgtataaaat agccaacacc gactacagtt
    13981 gcaaacacta gtgccattga cattaatagt ataggtttac gatattctaa taattttgtt
    14041 cgagagacgt gggtaccttc tacaaaaagt agtggcgcga taacggcaaa cataaacact
    14101 tcagaattga attggaaatc aacttgtatt ggaataatga aaataacgac acctaatgca
    14161 atttgaataa aggcagtagg aatttgtggg aatcgattat tgataaccga actaataatc
    14221 acagcaaaaa taaaaattaa aaatgcttct aatagtgcca tacaatactc ctcaaaattt
    14281 taatagttaa tattttatca cttttaaggc ataatgacat agatatattg ataaaatgaa
    14341 gttattttca aaaaaactct agtatcggtt gaactgatac tagagcgaga tgtttaaatt
    14401 attgattgtc atatctgaaa tgaccgctgt cattttgtcg ttgttcatac gcgagctttt
    14461 cagcattcgt tttgtatttt ttataaaaga aaaataaaaa tataaaccag aatggtgaaa
    14521 tataaatagc tgctcttgtt tcgtcactaa agaataataa aatgaataca aagaagaaga
    14581 acgctagaat aatgtaagca ataggcttac caccaatcaa cttaaattta ctgtttttat
    14641 gtgcctcagg atgctttttc aaatacatta gataagcgac aataatcatt gcccaaacaa
    14701 ctaaaaacaa cacagttgat aacgttgtaa cgtatatgaa tagttgaatt gcattaggga
    14761 aaatgtagtt taacaaggct gctataagta atgcaattga tgaaactaac attgataaat
    14821 aaggcacgcc atgactattc gttttattta aaactttagg acctaaccct tgttgtgaca
    14881 gtccgaataa gatacgacta ttcgaataga taccactatt tgtagcagag gccgcggcag
    14941 ttagcacgac aaagttaacg acgcctgctg caaatggcac gccgattaat gtaaagagtt
    15001 taacgaaagg gctactattt ggatcgatat cattccaagg tatgactgac ataattacta
    15061 atagaccacc gatatagaat aataaaatac ggataggtac attattaatt gctttcggta
    15121 aggttttttc aggatctttc gtttcaccag cagttacacc tataagttca ataccaatga
    15181 atgaatatac agcaatttgg aatgacatta ggaaaccaaa tgttcctcca gggaacatgc
    15241 cgccgtgact gattaagttt gtgaatgatg catgtccata atgtgtttta aatgagaaaa
    15301 agattaatac aagaccaacg ataaccatcg caataattgt gacaacttta ataatagaga
    15361 accaaaactc cagttcacca aataatctgg cacctaataa gttgaagcta atcaagatta
    15421 aaacaataaa tagcacggta atccaatttg ggacttgtgg ataccaaaat gcaaagtatt
    15481 gtcccatcgc agttaggtct gacatacttg atacaatcca acataaccag taagtccagc
    15541 caatgacaaa gccaccaaaa gggcctaaat attcatttgc aatatcaaca aatgaattaa
    15601 atcttgtatt gctcaacaac aattcgccta atgcgcgcat aaaagcgaat agtacaaccc
    15661 caataatcat gtatgtgaat aacagtgatg gaccagttaa agatattgtt tgacctgatc
    15721 ctaggaataa cccagttcca attgcgcccc caattgctat caattggatg tgtctgttat
    15781 tcaactctct atgcaatttt cttgccataa ttttcctcct caggataaag caaataaaaa
    15841 agttgtgtgt aagcgttttc ttaattataa atactaaaga aatccattta ataaagcaat
    15901 tattttttta aatataagaa aaaacatttg ataggtaagg gtatgataac taaaacttat
    15961 cgattttttg aaaagatata agtttttatg caaaaatata aaataatcat ctaaatgaag
    16021 cagttaacta tatatattag ataagctatg gcataataaa taacatttta atttgagtaa
    16081 agaaggtatg ggtatgaaga tagggacaat cgccgattta catattgatc gtcataataa
    16141 aaaaacatcc gaagattact tagaggcatt ggttgaaata gttaagtata agaaattgga
    16201 tatattgttg attgcgggag atatctcaaa tcattatcaa ttgacgcacc aatttataac
    16261 gcaattgaca aaacaattag atatacctgt gaaatttgtt cctggaaacc atgatttatg
    16321 ggaagttgaa agtatgacta cgcaagacat ttggaataat tataagagca tgtcacagtg
    16381 cttggtagga aaaccattta tagtaaatga agaatgggca ataataggac atacaggttg
    16441 gtatgattat agctttgcag cacaacgatt ttcattagaa catttacaaa aaggaaaaca
    16501 ttatggtgcg acttggcaag ataaagaacg aatatcttgg ggcatatcag atcaaaattt
    16561 atctaaaata gcggctgaac aagtgaagaa agatatatta gaagtaggaa atagacgagt
    16621 gattttagtc acacatgttg tgacgcaccc tgatttcatt gttcctatgc cacatcgtat
    16681 attcgatttt tataatgcat ttattgggac aagtgatttc aatcctttgt atgcgatgtt
    16741 cgatatacca tatagtatta tgggccatgt tcattttcgt aaaagtgtga tggatgatgg
    16801 cagatgttat ctctgtccgt gtctaggcta tccaagacaa tggcgttcag aagatattta
    16861 ccaggaaata aatgagacga tacaaataat agaaatttaa aatgcgcaaa cctgacccag
    16921 tttgcgcatt ttatgtttta cacacgcgag taatgtgttt acttacgtgt gtttattttg
    16981 ttgttgattt tcaattgtat atgaatgtgg ttgcacataa atgcattttc ttcctggtga
    17041 attaaagctg tattccattt tctctttacg aattttaata atttgtttgc gatttggaat
    17101 gatggcaggt aaaactaggc cacgacgaat atgactccaa agtggatcgt ataatagtaa
    17161 tagtaatcat cgtacccaat gagtaacgtt acgtgaatat ttgaaacttg tttcgctggc
    17221 ttgttatcaa agcggaaaac acgtagtaat ggtttagagc caagattagt atggtatatt
    17281 aacacaggtt gaccttgatc gataatacct ttaagatctt ctaaggattt accagtgccg
    17341 tctacgatat taggattgta tttttgtaaa aatggtacat atgcttctgg aaatatcgtt
    17401 tgatgataat tgccaagctt aatgaataag tgatgtccaa cataaccttt atgtggattg
    17461 ttcggatgtg tcggccaatg tctcataatt tctgtagcag ggatatgttg gttattgtat
    17521 tgcaacatca tggctgcgga aacaccttca caccccatga ccatagggat aggaaatagc
    17581 tgactgatag gtttaactgg taatattttt cggttcataa tatagtcctc gcattgattc
    17641 aataaatatt taatataatt atatagcgtc aatgcaaaat gtcctaaaca tatgttttac
    17701 atgagtgaat aaaattaatg gagtgataaa atggaatatc aattacaaca acttgcgtcg
    17761 ttaacgttag taggtattaa agaaacgtat gaaaatggac gacaggctca gcaacatata
    17821 gccgggtttt ggcaaaggtg ttatcaagag ggagtaattg cggatttaca gttaaaaaat
    17881 aatggtgatt tagccgggat acttggctta tgtatacccg aattagacgg taagatgtca
    17941 tatatgattg cagttaccgg agataatagt gctgatattg caaaatatga tatcataaca
    18001 ttagcaagtt caaagtatat ggtatttgaa gcacagggcg cagtacctaa agcagttcaa
    18061 caaaaaatgg aagaggttca tcactacata catcaatatc aagcaaatac ggtaaaatca
    18121 gcaccatttt ttgagttgta tcaggatggt gatactacaa gtgaaaaata tattacagaa
    18181 atttggatgc ctgttaaagg gtgattgaat agaaatgtac ttgatatgaa ggcgtaattt
    18241 tagttgaaga ttggatttca taattcataa agaagaaccc cgacaaagat agatatcttt
    18301 gctagggttc taattatgtt gaagtgttat gcgacatgtt gctttttaat cattttaaag
    18361 taaatgattt gtagactgac taatagaatg gctgtaatga agataataat catatatggt
    18421 gatgtattaa attcgccttt taagccaact aatggtgcaa cagcgccacc taagataaat
    18481 tggaataagc caagtaaact tgatgcgtta ccactgccac ctgttcgttc ttccatagcc
    18541 attgtgaaac caagtggtcc aattgacgtc acaggacaca catttaagaa gaatgcgatg
    18601 agtaagaccc aaagtggtaa atggaatgta agtgtcagga taattaaagc aacacccacc
    18661 acttgtataa tagttaaaat gattaataat atgtggcgat gtaatttttc tactaataaa
    18721 gcaacgactt gactgacaat gattaaacct acaccgttaa cagcaaacat gatactaaat
    18781 tgttggggtg tcatattata caatttttga gtaataaatg gcgatgcaga tgaataacta
    18841 aaaagcatta cataagttaa accttgtaat agcattggaa taataaatgc tggttttttc
    18901 aaaagacttc caaagtcttt aatgacgcta ctaaaattca cctgctttaa ttcatcttta
    18961 gatgttttag gtaattgaga agcgacgcca attaaaatga tgagtgccac aatagttaaa
    19021 attgtgaaaa tagaacgcca tgttgctacg gataaagcta atccaccagc taatggtgca
    19081 agaatagtga tgatgccatt tactaccatt aaagatgcta aaaatttagc gagtgcgttg
    19141 ccactaaatt tatcaccagc agaggctttg gcaatcacga tgacgccacc accagttaaa
    19201 ccttgaataa atcgtaaagt taagaataat ggcaattgat caacaaacat agacaaacct
    19261 gataccaaaa tgaaaatgat caaaatggat acagcaatcc gtttgcgacc aaaagcatcg
    19321 gataaaggtc caaagataaa ttggcctagt gcaagaccaa tcattgtgaa tgataatgtt
    19381 aattgaattt ctgatgtagt agaaccaaaa tcaccttgca ctttaggtaa tgatggtacg
    19441 tacatatcta tagttagtgg gccaaaagcg gtcatgacgc ctaacgtaat tagcaataaa
    19501 aatgaaaaat gcttcgtttt ggttttcgtt gattgcatga tcagactcct ttaaatgata
    19561 taattatata aattatatac gttttgtgtg tatttgtatg tagttagaat acaagtttat
    19621 ataaaaaatc cctatactct taatgcatca tcacgaataa cgtagtgata cagataaagt
    19681 atagggaatt aatgtttatc atcaaagcag gtgtaataat taattagcgc caccattgtc
    19741 atctttaaat aagctttcta atttagattt aatactgtcg aattttgtat taatatcatt
    19801 taacatgctt tcaattttac cttggcttgc attgttttta agtgcattat ttgcctctgt
    19861 caatttgttg atttggtctt gataaaattg agttagctta gaatcaactt tgttttgttc
    19921 ttgctgcttc aagttgtcga tttgattttg taaattttta ataatgtcat cagttttttg
    19981 gttgttttta atattttctt tagcattatc tacttgctgg ttaatttggc cgtcttgatt
    20041 ttcaacttgt tttttataat tttgagagac tttagggtca ttactaactt tatcgctatc
    20101 attgttaagt aaggcgcgtg tgacaaaaat agcgacaata attaagagaa tggcaataat
    20161 gatatataac catttttttg aacggcggga tttctcgttt tcttcttcaa gaatttgttc
    20221 tcttcgataa tctctaccat tatagtatcg ttccgggtgt tcttcaggat cgcctttagc
    20281 atattgttgt ctatacgatg cgtcttcaga ttgacgacga tgattttggt tttgattgtc
    20341 gtattgatat gaatcacggt atttatcagt tcttttcatg ggtttcacct cattcaagtt
    20401 ttaactgcaa ataataaagc tgatgattta ctttgacatt attgtaattt cagaatacga
    20461 gcaatgtcag ttgcagtgtt taataaattt tgttcgctat tttgtaggac atcttctaaa
    20521 gtgctaggtg aagagattat agaataggca ctatcaatac cgaaatcgta aacatgttga
    20581 taattttcgc ctagactgcc acaaatcgcg atgacaggaa tatgatattg ttttgcagct
    20641 aacgcaacgc ctacgggtgt tttaccaaag atggtctgat aatccatgcg tccttctcca
    20701 gtaataacga ggtctgcatc tttaattctt tgatgaaaat ctgtaatgtc aaagacgaca
    20761 tcaatacctt ttgttaaagt tgtctcacaa aacgctaata atgctgcgcc cataccgcca
    20821 gctgcaccag aacctggtat ttgattaacg gactttcctg tgcacatttt tatcttatca
    20881 tgataatgcg acattgcgaa atccaacttt ggtatcatct ttgcatcagc gcctttttga
    20941 ggaccataaa tataggtagc accattttca cccaataaag gatttgaaac atcacaggcc
    21001 actttaaagg tcacctcttt taatcgcgaa tctagattgg ttatatcgat ttgtgcaatg
    21061 tgagcaagat tagcaccatt catttgtaat aagtccccgt ttacatcagt aaactttacg
    21121 cctagtgcac ttagcatacc tgtaccacca tcatttgttg cactgccacc aatccctaaa
    21181 ataatggtct tagcaccatg atttaatgca tctttaatta gttcaccggt accatatgat
    21241 gatgtgtata aaggattacg ttcctctttt tctaataaat ccaaacctga cgctgccgcc
    21301 atttcaataa ttgcaatttg ttgttcgtct gcgcgtgcat aacatgcttc aataggtcgc
    21361 attaaagggt cattaacgat gactgtatac ttagtggcac ctgttgcatg cattaaagca
    21421 tctgtggtac cttcaccacc atcagccatc ggaatgatat cataatgaag ggtattccca
    21481 taaacattag taaatgcctg ttttataata ttgccaactt gctgtgcggt catactttcc
    21541 ttaaatgagt caggagcgat gacaattttt tgtaattgca tagtagacat cctctcatta
    21601 ctgttgtcgc tcttattgta tataaaatta ctagtgaact aaagtaatct ctatagtgct
    21661 aatgagtcac gcgataaatc agttacatta taatggcgta taaggatgag aggaaagaga
    21721 ctaaatttgc tgtgaaaggg tataaaggtt gaaataagta aatttgaagt gaagcggatt
    21781 ggctcgcata ttcgagtatg ttggagaacg tagctatgca tatattttga tgttgaggag
    21841 ttacacatat gaaactaaca caaacgcatg ctgaaatttt aaaatttatc attgttggcg
    21901 gcattaatac gttaaattat tatgttgtct atttattgct gttaaaatta ttacacattg
    21961 aatatatgat tagtcatatt accggatttc tagtcgcttt tgtgatttcg tattatttga
    22021 attgttattt tgtttacagg gtaaaaccta cttggagaaa attcattagt tttccaatta
    22081 cgcagattgt caacgtaagc ttacaaacag ttttattata tgtttttgta tcctggctaa
    22141 atttgccagc ggaaattgcg ccatttgcag gtttagtgat tacgataccc atcacatttg
    22201 tattatctaa atggatttta aaagatagta attaaagtag cgtaaaccac taaaaaacgc
    22261 tttactcgaa ctttaatatt gcgtgaaata taataaataa atgatataat ataatggtcg
    22321 cctaacatct cgggcgttac tttaacgcag agaggaggtg tatgatggat gttcaattta
    22381 ttaattaaca tcatgacttc agctttaagc ggctgtcttg ttgcgttttt tgcacattgg
    22441 ttacgaacgc gcaacaataa aaaaggtgac aaataaccaa cacctaaata aatcccctca
    22501 ctatggcagt agtgagggga tttggtgtat ttagatgttc aatttattat gtaattaatt
    22561 atagcattga taaacaaggt gtgcaatgta ttttgcaata ttacaataaa tgaatttaat
    22621 tatattagaa ttaagtattt cgaaaaatga tttaatagtt gagtcatagg atcattagat
    22681 aaagcgaata atcaattata gggacattgg gatacaaatc aatgtactag actctacaag
    22741 gctatactca gggacccaac atagagaatt tggatccaca gtttctacag acaatgcaag
    22801 ttggcggggc cccaacacag tagctggcgg aaagtcagct tacaataatg tgcaagttgg
    22861 cggagcccca acatagagtt ttactcatgt attcctattt ttaagtacat attagctgtg
    22921 gctaaggata aagaatcatt acataataaa tcattagtgg ctctttatca tttctgcccc
    22981 ataaccttgt gaatttttaa aagaaatgtg tcacaaatcc acgcgacatt gataatcgtt
    23041 atcaactaat atatgatgta cttgtaataa gtattaattt ttaacaaatg acaaatttat
    23101 attatgtata tcatccagtg aaataaataa tataagcggc ttaatttaga ttattaattg
    23161 aaaggagttg catatacgat gaacaatcag acaaattgga taaagatact cagcggattt
    23221 gcttctgata gtaaatggaa aattatgtta tcaattttgt tgtctatcat cagtgtcttt
    23281 tctggattag ttccatattg ggcagtcttt aaaattattt taatgatgat taacaatgca
    23341 tatacgatta attcgattat ggtttatatc tttattgctt taatcactta tatttcacaa
    23401 gtgtgttgtt ttggagcgtc aacgatgcta tcacatatta cggcatatga aattttatct
    23461 gaaattcgta aaaaattagc tcaaaaatta atgcgcctcc ctttaggcgt agtggaatct
    23521 aagaaaatag gtgaattaaa aaatatattt gtcgataagg ttgaaacaat agaattacct
    23581 ttagcacata tgattcctga agttatagga aacttacttt tgtcagctgc tatcttttta
    23641 tacataatgc tcattgattg gcgtatggct agtgccttat tagtaacgat accaatttca
    23701 attttcgctt ttaaaaaagt tatgtctgga tttaatgaga catatgctga acaaatgaaa
    23761 tcaaataatt atatgaatag cgcgattgta gagtttatcg aaggcattga agtgattaaa
    23821 acatttaatc aatctcaaag ttcatataaa aaatataaag atgcagtaga taattataag
    23881 attcacactt tgaattggtt taaaaataca tgggggtata tgaatttagg agctagtgta
    23941 ttaccttcaa catttttagg gattttaccg gtcggcatgt atttgatatc tatcaaccaa
    24001 ttaaactatg cggaattttt cctatgcatc gtattatctt taggtgtagt agcaccgatt
    24061 aagaatttta ctaattatgt aaatcattta aagtctatac aatacgcatt aactgaagtg
    24121 aatcaaatat taagtctaga agagttagta ttgtcaacaa aatttaagaa gcctcaacat
    24181 tatgaaattg cttttaataa tgttggattt tcatataaca aagataagga cgatctggtc
    24241 tttaagcatt tatcatttac agtaccagaa aataatttca cagctatcgt cggggcttct
    24301 ggtagcggta agtcaaccat tgccaagctt atatcacgat actgggatgt gacttcaggt
    24361 gaaattacga ttggcggtat aaatataaaa gatattgaat cgaaacaact taacgattta
    24421 gttggttttg ttggacaaga taacttttta ttaaatctta cttttaaaga aaatattaaa
    24481 cttggcaatc cagaagctac ggatgaggca gttgaaaaag ctgccaagtt agcacaatgt
    24541 catgaattta ttgaaaagtt gccagatgga tatgatacga atgttggtac agtgggagat
    24601 aaattgtctg gtggtgaaaa acaacgagtc actattgcaa gaatgatatt aaaagatgcg
    24661 cctatcattg tattagatga agcgactgct tacgttgatc cagacaacga acaaaaaatt
    24721 caagaagcat taaatgtgtt gacgcaggat aaaacattga ttgttattgc acatcggtta
    24781 tctacgattc aacatgcaga tcaaattatt gttttaggta aacaacaaat tttagaaaaa
    24841 gggtcacatc acttattgct aaaattaaac ggtaattata agaaaatgtg ggatacgcac
    24901 atgcatacaa aagattgggg aatcaatact ggacataatt aaactaatga gaaaaggagg
    24961 tcaaatatgt ttcaaattac atttaaaatt ttaaactgga taagaccata taaagcaaga
    25021 atgattttag gatttagcat gtcattttta aatgctattt ttattgcgtt acctatcttt
    25081 ttagctgcaa aaatatttaa taatgtgcta tctcataaac ctatttatat gaaagatata
    25141 ttgaatgttg taattatcat ggttttatta gtgattggac gatttattac agcatatttc
    25201 aaaagcaaaa gccatgagag catcgcttat gaaatgagtg cgaaagaacg tttagatata
    25261 ggggataaat tgaaaaatgt aaggttaggt tattttaatt cgcatcattc aaatgagtta
    25321 acaacaatag taacaacaga tttaacattt ctagaaaact ttgccatgaa aatggtagat
    25381 attattgtta atggatacat attaattaca gtactcatat tgtctctact tgtagtttcg
    25441 tggcaagtat cattattagc atgcattggc gtattactat cattttttgc gattcaatta
    25501 ttagaaagaa agagtcgaca aaatgcgcca gcgtatcata atgtacaaaa ccaattagtg
    25561 gaaaaggtat tggaggttat tcgtggtatt caagtaataa aatcattcgc gaaagaaaat
    25621 acgagtctta aaagttttaa ccaagcagtc aatgaaagta aacgtataaa tacaaaaata
    25681 gaaatgcaat atatcccatt caatttattg catttactta gtttaaaagt tgtttcaata
    25741 atgattgtat tagttgcatg cttattatat atgaatcata gtattgattt acctaccctt
    25801 attatgattt caattttttc atttgtgata tttgatagtg ttgaaaatat taatagtgct
    25861 gcacacgtac ttgaaatgat agatatgacg atagatgata ttgaaaagat aaaaaatgct
    25921 ccagaactgg atgagaatgg aaaaaatttg acgattaaaa atgaaaatat cgcttttcaa
    25981 aacgtgaact tttcatatga tgataaacaa gtgataaaga atgtgaattt tgagatacct
    26041 acacaaacat caacagcaat aattggacct tcaggaagtg ggaaatctac attatgtcac
    26101 ttactcttgc gcttttatga tatcgatgat ggaaatattc gcatcgatgg tgttgatatt
    26161 aaagatatga cattaagtac gttaatgtcg aaaattagtg cagtatttca aaaggtgtat
    26221 ttatttaatg atacgattga aaataacata ttgtttggca atccaggtgc aacgaaagaa
    26281 gaaattattc gtgcagcgaa gcaagcatgt tgccacgact tcatcatgtc attacctgag
    26341 ggatatcaaa caatgctaaa tgaaaaaggt agtaatttat ctggcggaga aaagcaaagg
    26401 atttctattg ctagggcgat attaaaagat gcaccaataa ttattttaga tgaagcaact
    26461 gcaagtattg accctgaaaa tgaacagctg attcaaacgg caattaatga attaagtaaa
    26521 ggcaaaacag taattacaat tgcacataaa cttgaaacta ttaaaaatgc agatcagatt
    26581 atagtgctca atgaaggtga aataattcaa aaaggtagtc atgatgaatt aattcgaaaa
    26641 ccaggaatgt atcaagactt tataagaata aaaagtaaat cagcaggctg gaaattataa
    26701 ataatagttt aatatggaat cagaatttgg aaataaaaag ggtgatagat aatcaacagc
    26761 aaaataaatc ccctcactag ggcaatagtg aggggatttg gtatatttag atgttcaatt
    26821 tattatgtaa ctaattatag cattgatgaa caaggcgctc aacgtaatat tacaattaat
    26881 ggattgtttc acaacatggt aaagctagga tgtctttttg ttaagaaata atgcaattat
    26941 taattttaac tgacatattt taacgaatcg ctgtttatat ctgcccaaat ttcgtaagaa
    27001 gccttagtca tttcaatagc aaggtcaaaa ttttgccaaa aattatagtt atactgagaa
    27061 gtttaaattc atgttttctt gaaaaacatg cgccttaaat gtaaacttat taattataaa
    27121 agtttacatt cggattgagg tgcttatttt ttatgaggat ttttattaca agtacgaata
    27181 ctgatgtagg caaaacctat gttacaaagc atttatacca tgctttgaaa acacgtggtc
    27241 atcgtgtttg tgtttttaaa ccatttcaaa ctgaggaacg ccaagacggg acatttccag
    27301 atttagaagt atttaaaaat gaatgtgatt taagctatga cataacgtca ctttatactt
    27361 ttaagcaacc tgtatcacca caccttgcat ttaaaatgac agatcaaatt tttctaaata
    27421 agcagcgtgt attagataag gtaaaagttt tagataagga atttgatttt atcttaattg
    27481 agggtgctgg gggaattgcc gtaccaatat atgaaggtac agatgatttc tacatgacta
    27541 aagatctaat caatgattgt gcagattgtg tcatcagtgt gttgccatca aaattaggtg
    27601 ctattagcga tgccgttgtt caccaagatt atgttaataa gaatgtatcg gcgagtaatt
    27661 ttttaataat gaatcgctat acagacagct atattgaaaa agacaatcaa attacgattg
    27721 gaaaattaac aaataaaaca gtctatacat ttgaagaaca tgccacgtat gaaaatttct
    27781 cagaagcatt tttaaaacaa ttaataggag ttaaaaatga attacacaca acaacttaaa
    27841 caaaaagact cagaatatgt ttggcatcca tttacacaaa tgggtgtata tagcaaagaa
    27901 gaagcaatca tcattgaaaa aggaaagggt agttaccttt acgatacgaa tggcaataaa
    27961 tatttagatg gttatgcatc gttgtgggtc aatgtgcatg gtcataataa caaatacttg
    28021 aataaggtaa ttaaaaagca actcaataaa attgcccatt ctacgctgct aggatcatca
    28081 aatattccgt caatagaact tgcggaaaaa ttaatcgaaa tcacgccaag taatctaaga
    28141 aaagtatttt attctgatac aggcagtgcg tctgttgaaa tcgcaataaa gatggcatat
    28201 cagtattgga aaaatattga tagagaaaaa tatgccaaga aaaacaagtt tataacgcta
    28261 aatcacggtt atcatgggga tacgattggt gcggtaagtg ttggtggtat caagaccttt
    28321 cataaaatat ttaaagactt aatatttgag aatattcaag tagaaagccc atctttctat
    28381 cgcagtaatt acgatactga aaatgaaatt atgacagcta ttttaacgaa tatagagcaa
    28441 attctaattg aaagaaatga tgaaatcgca gggtttatat tggaaccgtt gattcaaggt
    28501 gcgacaggct tgtttgttca tcctaaaggc tttttgaaag aagtcgagaa attgtgcaaa
    28561 aaatacgatg tcttattaat ttgtgatgag gtagcagttg gttttgggag aactggaaag
    28621 atgtttgcat gcaatcatga agatgttcaa ccggatatta tgtgtttagg taaggcgatt
    28681 actggtggct acttaccact tgcagctaca ttgacatctc aaaaaatata caatacattt
    28741 ttaagtgatt cgcatggtgt taataccttt ttccatggtc atacatacac cggaaatcaa
    28801 atcgtttgta cggttgcatt agaaaatata agactttatg aaaaacgtaa gttattgtca
    28861 catattgaaa cgacatcatc aacacttgag aaacagttac atgcgctgaa gcgtcatcga
    28921 aatgttggtg atgtaagagg acgaggctta atgtttggag ttgaattagt tacagataaa
    28981 gatagtaaaa cgccgttaga aattgaaaaa gttgaacgta ttgtacgtaa atgtaaagaa
    29041 aacgggctaa tgattagaaa tttagaaaat gtcattacgt ttgtgccagt gttaagtatg
    29101 tcaaataaag aagtgaaaac gatggtacgt atttttaaaa aggcagtaca taacatttta
    29161 gataggaagt gttaatatga atttggctaa acgcatatta caaggggaac aattaacaaa
    29221 agagactgta ttgaaaattt atgaggatac taatattgat accttagatt tattaaatga
    29281 ggcgtacatt ttaagaaaac attattttgg taaaaaagta aaattaaaca tgattttaaa
    29341 tgctaaaagt ggtatatgtc ctgagaattg tgggtactgt ggacaatcac gagatattaa
    29401 acaaaaacag cgatatgctt taattccaga ggaacaaatt atcgatggag caaaggtggc
    29461 acatgataat catattggaa catattgtat tgttatgagt ggtagaggac cgagcgataa
    29521 agaagttgat catattagta atactgtaag aacgattaaa tctcaacacc cgcaactaaa
    29581 aatctgtgca tgtttaggat taacgaatga cgaacaagct aagaaactta agtcagctgg
    29641 tgtagacaga tataaccaca atattaatac aagtgaaaat taccatgata acgtcgtgac
    29701 aacgcatagt tataaagata gaacagatac gatagaacta atgaaagcga ataatatatc
    29761 accatgttct ggcgtgattt gtggtatggg agaatctaat caagatattg ttgatatggc
    29821 atttgcttta aaagaaatgg atgccgacag tattccgatt aattttttgc atccaatcaa
    29881 aggcacaaag tttggaagca tggatgattt aacaccaatg aaatgtttaa gaatcgtagc
    29941 attattccga ttaatcaatc ctacgaaaga aattcgtatt gctggaggaa gagaggtcaa
    30001 cttacgttcg ttacagccat tagcattaaa agcggcgaat tcaatatttg tcggtgatta
    30061 tctaattact ggtgggcaac cgaaccaatt agactacgat atgattaatg atttgggctt
    30121 tgaaattgat tatgacactt gtgaaaataa ggaaaacaag aatgatgttt caagagcaaa
    30181 ttgatttatt acaacagaaa gggttatatc ggtcgcttaa atcggtaggg tatatagata
    30241 gacagtatat tgaagtagaa aataagagat gtacgaacta tacatctaat gattatttag
    30301 gattaggtca aatagcgttt gataaggatg atttcgaaag atttatgcgg aagtatagtt
    30361 atcacttatc aagttcaaga ttaattagtg gaagttcgac agcttatgaa gaaattgaaa
    30421 caatgttagc aggttggctc ggatatagtg catgtactat cttaaatagt ggttatgatg
    30481 ctaatttggc gttgtttaat attttcaaaa atacaaattg tgtcgtgttt tcagatcaag
    30541 aaaatcatgc gagtattatt gacggtatta agttaagtgg tttagaaaaa gtgatatata
    30601 agcatttaga tattgctgat ttagaaaaaa ggttagagaa ataccctaat caaaatatac
    30661 caaaaataat catatctgat agtgtatttt caacgaatgg cgacgttgtg gatattggtc
    30721 aattagtctc attaaagcat aaatataacg caacactgat actcgatgtt tcacatagtt
    30781 ttggaataga gaattactcg aattatcaag gtgtagatat actcacttct agtttatcta
    30841 aagcatgtgg tgcatacggg ggtgtgattt taagttcaaa tgatgtgaag gatatgttaa
    30901 ttaatcacgg tagaccactc atctactcaa gtagtttgcc aatttataat ttgtatttta
    30961 taaaaagaaa cattgaaaag ttaataaatg ctgatgatag acgcactaaa ttaaatagtt
    31021 tgagtaaata ttttaaccaa aagttaaaag cactcaatgt taattataat agttcaaact
    31081 cgccgattaa gtttattgag tttgatgaca tagaagcggc tgagaacatt catcaaacat
    31141 tattaaagca tcatgtgttt acaagttatt taaggtatcc aactgtgact aagccaatgt
    31201 taagaatatc attgtcgtat tttcatactg aacaagatat agataggttg tttgaaattt
    31261 tgcatcaaga agattgaggt gatcgtcatg tatagtataa aaatgcgttc tagcaatcaa
    31321 gatgttcata ttagtggtgc tgaaacgatt tgtgagtttg acaaaataga acagacggta
    31381 caaaggtttt ataataaagg tttttttcat gaaaatgggc aaccggattt tctcaatata
    31441 aaaatacaaa aaattatgga accgattcaa caaataaaag cattacaaat tattgaggat
    31501 gataaagcaa atctccaaca tttaacacaa gaatgtggtg tcactgaaca agcgctaaat
    31561 caagggatga catatattaa aaatgaaacg gtttatacag gagctattat tctatctgct
    31621 atatctggta aacgtttaga ttcatttgga caaaggggga ttagggcaac acatttttcg
    31681 tttgaagata taaataataa aggtgatctt aatgaaagag tgactgatgc cttagcaatt
    31741 gctagttgta tcaatgcgca tccgtatgtc aaaggagaac tttgcgtgtc cgatgactta
    31801 acgtatacga caggttattt tgccgctgct aaaattggtt accatcgatt atttgatatt
    31861 aaaccagtta atacgagata tggaggcgga ataatatttg tggacgattg tattgattta
    31921 aatcattaca tatcattttt agaaagcaca ccgaagcaag ttgtttatga aacggtatag
    31981 gggttttagt atgacatcaa aagatattac tcaaattagt gtcattgctg cgattttaac
    32041 cattttggca gttttgaaaa taccgtccat tataccagga ttagattttc aattatctgc
    32101 accggcagca ttattgatat tagctttctt tggaattaaa aagtactttt taggtgggct
    32161 tttatcaagc gtattattac tgatatttgg cgtatttaat ccaattaatg tgattatttc
    32221 tattatattt agagttatag ctattgcagt tgtttattta ttgaaaataa atgtactatc
    32281 attagtttta tcaagtgtat taggcagttt ggtatctagg ctactattat ctattatttt
    32341 aaatttacct gtgtgggtag tgttgttaaa cgcgattcca ggcgtaatat tcactttaat
    32401 tgtagctatt cctttatatc tcacattgag aaaaagaatg gcagtcttac taagataata
    32461 aatcaaaaca cggtcgtcac aattactgtt ggcgaccgtg ttttactagc tatttattgt
    32521 tttcagtttc ttttgtatct aacaatttca ctttgtgatt ttcccaatca atttcatatg
    32581 ttgatttaaa tgttctagtt ttaaagtttt tataatttgc gcctgcccag tagaagccat
    32641 tccaacgaat ttggtataaa tccatttcac gttgataagt tactgtaatt ttagattttt
    32701 tagcgccatc ttgtctgtgt gatagtacgc ttaaaaattc tggattgaag ttacttctag
    32761 ataataatgg catttggtgt tgcgctatga agttttggcc agcgtatgca ctgctttgtc
    32821 tgccagctaa gaagagttca ttaccatatg ttgggtggaa gctatctctt ccataaggtc
    32881 cccaaccatt attcataatt ttatgtgctt caactcccca gccaacattt ttataatttg
    32941 tgttgcgact taatgttgtt ctgtaacttt cttgtttata attaattgtt tcagaaaaag
    33001 ctgtatttcc attaagtcca ccagataaac cattagagat actaatgtca ccaccaaatg
    33061 tatagcctaa agtattttga acttgaaact cttcattttg attttttggt gcataatcaa
    33121 cgacgtttac tgaatcatta gattgtgagc ttatagatac attgtattta gctccccaat
    33181 ataattttga aaagtcatag tcattaggat taggtttcac aaagcctgag ttaatattcc
    33241 cagtagcttt aagtactaaa gtatctttat cataactttt atctttgatg aaattaaatg
    33301 ttaaaatctg tgaaatttta aacttatcag aatctgctgt ggctgttgtt ttgtataaag
    33361 taactttgtc atcgactttt tttacgctga ctggtgttat tttaccttca gcattagcag
    33421 taccagaaag taataataat gccatagatg tagcaacgga tgatttgact aatttattca
    33481 ttttcatatc aattctgtcc tttcaccttg atttcatgag tcttccaatt gacctcgtat
    33541 ttaacagtat agtttctatt tacgaatgca ttatggactc tatgtccgtc taaataactg
    33601 ttgccataat gcgttgatct tttaatggca tgagtgacat ccatgtttct tccgtaagta
    33661 atttcaaatt cgcttgtatc gcttgaacct ttttcatgag atactgtggc gataaatgaa
    33721 gggttaaatc cactttgtac aagaggaggt aactcactgt ctggaacgaa ataatctcta
    33781 ggatctttac tatgaggttt gtagcctaca aataaatcgc tatcaaatgc tgatttttga
    33841 cctgattcag tggcgaatga attcgctttg acgccccata aaacactttt tgagttttgt
    33901 tgttctactt cacttacata attttgttgt gtatagctaa tcgatttaga atagttaaat
    33961 gatccattac caccgagtga tggggctgat tggaaattac caccgatatt gtatcctaat
    34021 gtctgactca cgtttgtaga ttcaatttta tttttaggta aataattaat taaagaaaca
    34081 tatttatcat ttgtttttaa accaatatta tattggaatg gccatcgcat agctttaaca
    34141 tgattagttt ttttatagtt gtaatatgtt gttctagagc taatgaatcc ttgcatcttt
    34201 aatatcagag catctttgtt atatttttta tccttcacaa aatcaaattg aatattttga
    34261 gtcacgcccc atttattact tgttttatct tctgtccttt tgataatttc tatatcgctt
    34321 cctttaccga tgtcttcagt atcgttggca gctttagcat tttctaataa cggattggca
    34381 agaagggcaa gtaagctcac agataaagtt gtagctaata ttttattttt aagcataagt
    34441 ttcactttct ttctataatt ttatttaact taattaaata ataatatatt ttggacgtta
    34501 ttataattaa ctgttcatta acaattgacc attatcaact ttttttacaa ttaagttaaa
    34561 aatgccataa ttccgttcaa tttaaccttt tttgtttgga atgctaaaag ctaattttgt
    34621 gagaaatata gttaataaaa ccttggtatt gttgacagtt gtaaacaatt taaggtaacc
    34681 gattgcacga atgtcttgct tttattttta attaatgttt gtaaaataca aattgttctt
    34741 tttacgattt ttgatgaatc catctaaaag ttaattattt attaacttga gaatatttat
    34801 ttaagctttc aacttaaatg gattcatttg tattatttgt gtatctactc tggtgcgata
    34861 ctttgttctt ataaaaatca gttgttatta ttaaatttaa tgtacgataa attaatttaa
    34921 tgttatgagg ctgattcaat atgttaaaaa atcctgagac aagtatgaag tgtcccagga
    34981 ttttttaaaa tgattgaact gtttacttag gtgtgatgct tttaattttt acttcatgtg
    35041 ttttccagtt cacttcatat ttaactgtaa cgtttcggtt tttaaaagca tcatgttttc
    35101 tatcaacggc taaacgatgt cttgtcacgt aagcatatgt agcatccatg tttctgccgt
    35161 aagtgatttc aaactcgctt ttatcacctt tacctctttc gtgtgacaat gttgtaataa
    35221 atgatggatt aaagccactt tgaattaaag gaggtaattg attatctggg acgaaatagt
    35281 ctcttgctgc tggaccagtt gggtcttgtg caaataagta ttgatcatat gcagatactt
    35341 gaccattcgg tgtaacaaat gaatttgctt tcactcccca tttaacacct ttagagttct
    35401 gactttctac ttcagtaaca tagttttttt gattataact aattgtttta gagtagttga
    35461 atgagccact gcctccgatt gatggcgctg attggaagtt tccgccgata ttatagccta
    35521 atttctgact aacatctgct gaatcaattt tatttttagg aagataattg attaaatcaa
    35581 cattagagtc tttcgttttc aaactgatat tatattgaaa tggccatatc attcttttaa
    35641 tatatggata tttttttaag tctgaatatg ttgttctaga gctgatgaag ccttgcatct
    35701 taacaactag ggcatctttg ttatattttt tatcttttac aaaatcaaat tgaatgtttt
    35761 gagttatagc taatcgtttg ctagtaatgt cttgtgttct tttgatgatt tctgcacctt
    35821 gaccgatatc ttctatctta ttttctgctt tagaaatttc tataaatgga ttggctaaag
    35881 gggctattaa accaactgct aaagttgctg ttaatatttt atttttaatc atagaaatca
    35941 ctttctttct atttaatttt aagttcatat atataataat ccatttgtaa gcgttttcga
    36001 attaactgtt cgttaaaagt taattactat caacatgtat tgaagagaca tttttagcat
    36061 tgttaaatga tgtttttgca ttatgttatg tttaaaagat ttattggtcg caggcgttta
    36121 tatagcgaca taactatgtt ttgcaagtct tattctattg aattgttgtt taattatggt
    36181 gcttgtagtg gaagaggaat ggatttcgca atagtttgtg aaaatttgaa gttaataaag
    36241 ttgagctgat tcaactaaat gatgaactat tcgttaacga tgtaaggatt atttaacaag
    36301 ttgcaggtaa agaagtggac tgacaaatag cgaagaaaca tttaattgat ggaaaataaa
    36361 aaaagaacca cagattcgat tgagaatcag cggttctttt taatcacggt ttattacgaa
    36421 aattatttaa aaaatgatgt aaaactagag aagatatttt tgattgatta tttccagaat
    36481 gataataaat tacttaatgt atttttgatt gatgatgcag tttcttgagc tttaatagct
    36541 gtttttacta atgttgggtt ttggtagaaa gtatataata ctttaccagt attgattgac
    36601 tcagttacat agtttcttac ttgtgcatat gatttagcta agtagccgtt tttatcatca
    36661 actttcaatg gttggatgta agatttagaa ccactaccta gtactgttaa tactgtttga
    36721 tcaatcgcac ctttgtattt atagtacgta ttatagtagt actttgctgt atcatatttt
    36781 tctttatagc ttttataagt atctgttaaa tacttgtaac catagttaaa tgaatctttt
    36841 aatgattggt agtaacctaa taatttagat tgaggaacct caacttttgg tgattggatt
    36901 tgagggactt caacttttgg tgattctgct ttaggttttt caatttgtgg tgattgaatt
    36961 tgaggagcct caacttttgg cgccactttc ttttcagcat ctttttgagc tactaatgcg
    37021 tctaattgtt tctgtaaatg ctcttttaca tccataggtg ctttgttaac ttcacgttgt
    37081 gctaaacgtc tgttttcaat tgaatctttt tcatttaatt ttgagattgc atcatttgct
    37141 gatttcacac gctcatcatg acgaacgatt gctttttcaa ttgaaacttt ttctacaaag
    37201 cggttatttt tatcgcgtaa atctttaggt aattttgagt tagcttcata tgctgctgat
    37261 ttatcgtgtg gtgctttgtt atcttggaaa tctttaattg ctttatccgc attttcaata
    37321 ttttgacgtt ctttagcttt agaagattgt actgattcta cccaaacttg ttggcttcta
    37381 tcagggtttt ctttaatttg tgcaatgtaa ttattttttt cttgttcagt taagttatca
    37441 tttttaagaa cattgtaaaa agcgttttgt tgtgcaacac gtcggtctgg gttcttgctg
    37501 tctttaagtg attcagagaa tacttcttgt gcacgttctg ggtgttcgcg taatgttttg
    37561 atgtattggt tacgttgttc ttctgtgata ccttttagat gtaatacttg ataaaaagct
    37621 ttttgttgat ctgttacgta gttgttttga gttgtttggt gcttagttga agtttgttgc
    37681 gtgttttcac tcgcttttgc ttccccattt gaaatcattg tagctaaagt aattgttgct
    37741 gccccaacta gcaacttcga gatatattta tttttcatgt gtattccctt tctttttaca
    37801 tattaaattt attgtatgct tttagaattt atcacatgag aatacaaatg gaaattaact
    37861 aattattaac taatgttaac taatagatta actagtgtta actatgtaaa aaagcgttta
    37921 attcagaaca ttcagcgtat tttaagtaag gaagtactat atggagaaat gcaatagttt
    37981 gctaataaat agaggaggaa attgtctttc gaagagagtt tggtagagta gaaatctcat
    38041 ttaatttgtc actgatgcac tttttcttct atataattag gtcacgacat tagatagctt
    38101 cgcaactaat gcatagggtc ccaacataga aactttcgag gcgaaagttc acaaacagga
    38161 agagttgggc ggctttctag ctcataaaat tcgcagaaaa taaaggaacg cattagatag
    38221 cttcgctact aatgcattgg gtcccaacat agaaactttc gagacgaaag ttaacaaaca
    38281 gggagagttg ggtgcctttc taacaaataa atttgaagaa gacgaaggaa cgcagttgga
    38341 cgtaaaacgt caactgcata agcctttcta gctcataaaa ttcgcagaaa ataaaggaac
    38401 gcattagata gcatcgctac taatgcataa gcctttctaa caaataaatt tgaagaaagg
    38461 ctaaaaatta tttttagggg ttgcgaatga ataaattagt ttaattttat aaaaatttat
    38521 aaaaattaaa aacgttgtaa aattaaaatg aatcattcat aatattgtta ctatactaat
    38581 tcaaggtggt tcaacgcatg tctcataatg aaaatcttaa attggcgcaa cgcggtgctt
    38641 atttgagttt aattgtatat ataatcttat ctattgttaa gtatgtcacg ggttttgtct
    38701 ttaactctgc agctgtaaga gccgacgcat taaacaatat gacagatatt atcgtttctt
    38761 tagctgttat tattggattg aaaatttcaa ttaaacctgc cgatcgaaat catccttatg
    38821 gccatttgaa gtctgaaaat atttcttcat tattggtgtc atttgtcatt atgtttgtag
    38881 gtatccaagt agttattcaa aatgcacctc gtttgttcaa agaagatgac gttgtaccta
    38941 acgcaataac aattatcgtc agcttaatca gtggtcttgt aatgttgatt gtatttgcag
    39001 tcaatcaaag actagcgaaa agaacgaaaa gtagttcttt aaattcggct gccaaagata
    39061 atttatcaga tagtttagtc agcattggaa cagcgatagg attaattttt acgcaaatcg
    39121 gtttcccaat tgtcgatatt attttagcaa cattactagg cttactaatc gtttatactg
    39181 gttttggtat ttttaaagaa gcaattttta tgttgagtga tggtttcaat gaaactgaat
    39241 tagaagcgta tcgcaatgat attttagaag ttgatgaagt acaagaagtt aaaagtatta
    39301 aagggcgtta ccatggaagt agtgtgttta ttgatgtcac aattgttgta gatgctaacc
    39361 tttccttagt agaagcgcat caaatttgtg acaatgtcga acatcatttg cacaaaaaag
    39421 gtatttcctc agtatacgtt cacccagaac cagaccatct ataatgtatt taaacgtctt
    39481 catagatata taaatatctg aggaggcgtt tttattacat ctatttttag gcttacctaa
    39541 aaatattttt taaaccttag aaaaatagcg aacaaaggtg tataatatga tttgttatta
    39601 ggtggttatt gattcattta tgaattaaaa aatgaaaatg gggaatagga tttatgtatt
    39661 taatgtctag tgataattga tttaatcatt gaattttaaa atatattgaa aagaaaatta
    39721 ctaagattaa atcatcttaa aatatccctg aaataacgtc ctaaagatta aaggaaagag
    39781 gttataagtt atgccaaaat taattttatg tcgtcatgga caaagcgagt ggaatgctaa
    39841 aaacttattt actggatggg aagatgttaa tttatctgaa caaggtatta atgaagcgac
    39901 tagagcaggt gaaaaagtaa gagaaaataa cattgccatc gatgtagctt ttacatcgtt
    39961 attaacacgt gctttagata caacgcatta tattttaact gaatctaaac aacaatggat
    40021 tcctgtatat aaaagctggc gtttaaatga acgccactat ggtggattgc aaggcttaaa
    40081 taaagatgat gctagaaaag aatttggaga agaacaagta catatttggc gtcgttctta
    40141 tgatgtgaaa ccacctgctg aaaccgaaga acaacgtgaa gcttacttag ctgatcgtcg
    40201 atataatcat ttagataaac gtatgatgcc ttattctgaa agtctgaaag atactttagt
    40261 tcgagtgata ccattttgga cagatcatat ttcacaatat ttgctagatg gtcaaacggt
    40321 attagtttct gcacacggaa attcaattcg cgcattaatt aaatatcttg aagatgtgtc
    40381 agatgaagat atcattaatt atgaaattaa aacaggtgca ccgcttgttt atgaattaac
    40441 ggatgattta gaagttatag ataaatacta cttataaaaa aagagctgca tgtacacaag
    40501 gagtgagtgt atatgcagct cttaaatatg tgaagtaatg taaggaaata gttaagtata
    40561 gagtttatat taacgagcta gggatactcg aaaatatagt tagacataca atatagtcaa
    40621 attaaaacaa ttatttcgct cttttgtgtt gcttaataat ctttaaagca cgctttcttg
    40681 ttttaatgtt agggctattt aaatttcgac gagcagtctg taaatctaat ttcatctcta
    40741 tccctccttg taaatatatt atgaccgata actactcata tgtaaatagt aatgattacg
    40801 ttttaaagaa attgtaataa agtcgtgcta attttttgga aaatgggtat aattaccgga
    40861 tatctaaaaa tgtgtgtcgt tttttagatg gtgaggggga agctttaaat gtcgaagaaa
    40921 caaaaattaa cgatgattat tactatgctg atgggtggat tttttggatt attaaatgaa
    40981 acactattag tgacggcttt accaagtatt atgaaagatt ttgaaatttc atatacacaa
    41041 gttcaatggc tgacaacagc ttttttattg actaatggga ttgttattcc tttgtccgcg
    41101 cttgttatac aacgttatac aacaagacaa gtgtttttag tgggtatttc tatctttttc
    41161 ttaggtacat tactcggcgg cttgagtccg cactttgcaa cattattagt tgctagaatt
    41221 attcaggcgt taggcgcagg tattatgatg ccattgatga tgacaacgat tttggatgtt
    41281 ttccaaccgc atgaacgcgg taaatatatg gggatatttg gtttggtaat tggtttagca
    41341 ccagctattg gacctactct ttcaggttac cttgttgaat atttaaactg gagatcgctt
    41401 ttccatgttg tcgctccaat tgcagctgtt acatttttaa ttggatttaa aacgataaaa
    41461 aatgttggaa ctacaattaa agtacctatt gattttattt ctgtcatttt ttctgtacta
    41521 ggtttcggcg ggttattgta tggaacgagt tcaatttcag aaaaaggttt tgataatcct
    41581 atcgtattag tatctatgat tggaggcgtt gttttagtcg cattatttgt attacgtcaa
    41641 tatcggctat caacaccatt attaaatttt gctgtattta aaaataaaca atttacagtt
    41701 ggtatcatta ttatgggtgt cacaatggta tcgatgattg gttcggaaac gattttacct
    41761 atctttgtgc aaaatttatt gcatcgttca gctttagatt ctggattaac tttattacca
    41821 ggagcaattg ttatggcatt tatgtcgatg acttcgggtg ctttatatga aaagtttggt
    41881 cctagaaagc ttgctttagt aggtatggcg attgttgtta ttactacggc ttattttgtt
    41941 gtaatggatg aacaaacatc aacaatcatg ttggcaacag tttatgcgat tcgaatggtt
    42001 ggtatcgcgt taggattaat tccagtaatg acccatacga tgaatcaatt aaagccagaa
    42061 atgaatgcac acggttcatc tatgacaaac acagtacaac aaattgctgg ttctatcgga
    42121 acagctgcat taattactat tttatctcat gcaagcaaaa acttttctcc aactatgtca
    42181 gactataatg gcatgaacaa aattgatatg atgaatcaaa ttaaagttga tacgatgttg
    42241 catggttatc acgctggatt tttatttgca ttattgatta cagttgttag tttcttttgt
    42301 tcatttatgt tacaagggaa gaaaaaagaa gttgattctc gtcaataaat ataagttgct
    42361 agctatataa agctttttag caaaagttca acatattgac ttatccggca tttcagatta
    42421 aaatattttt attccgatta gaataataag aataaggaga tatattctat gaaaagactt
    42481 ttatttgtga tgatagcttt cgttttcata ttggctgcat gtggaaacaa ttcgtcgaaa
    42541 gacaaggaag ctaataaaga tagcaagaca attaatgttg gtactgaggg gacttatgca
    42601 ccatttagtt tccatgataa agatggtaaa ttaactggtt acgatattga tgttattaaa
    42661 gcagtggcta aagaagaagg tttaaaactt aaatttaatg aaacttcttg ggattctatg
    42721 tttgcaggtt tagacgcagg gcgttttgat gtaatcgcga accaagtagg tattaatcct
    42781 gatagagaaa agaaatataa attttctaag ccttacacat tctcaagtgc tgttttagtt
    42841 attcgtgaaa atgaaaaaga tattaaagat tttgatgatg ttaaaggtaa gaagttagca
    42901 caaacattca catctaatta tggtaaatta gctaaggata aaggtgctga tattacaaaa
    42961 gttgatggct ttaaccaatc aatggattta ttattgtcta agcgtgttga tggtacattt
    43021 aatgatagtc tgtcatactt ggattataaa aaacaaaaac ctaatgctaa gatcaaagca
    43081 atcaaaggta atgctgaaca aagtagatct gcatttgcat tttctaaaaa agcagatgat
    43141 gaaacagttc aaaaattcaa tgatggcttg aaaaaaatcg aggaaaacgg tgaattagct
    43201 aaaataggta agaaatggtt tggtcaagat gtttctaaat ctaaatagcg aacaacaaca
    43261 tgcgctagat gctgcaaaac aagctttcgg acctatgcta gaaggtttgg tcaaatattc
    43321 aattcctatt acattagtta catttgtttt aggattgatt attgcattat ttacagcatt
    43381 aatgcgaatt tcaacgagta aaattttaag aagtatttca cgtgtctatg tatctattat
    43441 tcgaggaaca ccaatgatag tacaactatt tatcatattt tatggtattc cagaattagg
    43501 tagattatta acaaatgacg ctgacaacca atggacattg gcacctgtag tggctgctat
    43561 tattggttta tcattaaatg taggtgcgta tgcttcggaa attattcgtg gcggtattat
    43621 ttctataccg aaaggacaaa cagaagctgc atattccatc ggtatgacgt atggtcaaac
    43681 gatacaacgt atcattttac cgcaggcaat tcgagtgtcg attcctgcac taggtaatac
    43741 atttttaagt ttaatcaaag atacatcatt attaggattt attttagtgg ctgaaatgtt
    43801 tagaaaagct caagaagttg cgtctacaac atatgaatat ttaacaattt atgtgttagt
    43861 tgcgctaatg tactgggtgg tatgctttat tatttcaatt atccaaggta tctatgaatc
    43921 ttatattgaa agagggtatc gctcatgatt caattgaaca atatccataa atcatttaat
    43981 gatgttgaag tcatcaaagg tattgattta tctgttgaac aaggtgaggt tgtaacctta
    44041 atcggtcgat ctggttcagg taaaacaaca ttgttacgta tgattaatgc attagaaatt
    44101 ccaactgaag gtacagttta tgttaacggc aaaacatata catctaaaga taaaaaatca
    44161 caaatagaag ttcgtaaaca gtctggcatg gtatttcaaa gttataacct ttttccgcat
    44221 aagacggcat tagaaaatgt aatggaaggt cttatcacag ttaaaaagtt gaaaaaggat
    44281 gaggcacgtg ggaaatcact tgagttactt gagaaagttg gtttaacaca tgtcaaagat
    44341 caacgtccac atgcattatc aggtggtcaa caacaacgtg ttgctattgc aagagcacta
    44401 gcaatgaacc ctaaagtgat gttgtttgat gaaccaacat ctgcacttga tcctgaactt
    44461 gtgaatgatg ttttaaaggt tattaaagat ttggctaatg aaggcatgac aatggtcatt
    44521 gtgacacatg aaatgcgttt tgcaaaagaa gtatctaata acattgtatt tattcatgaa
    44581 ggcatgatcg gagaacaagg ggctccagaa gagatgttca atcgtccgaa aacagaagaa
    44641 ttaagacgtt tcttaaatgt tataaatgaa gaataatcaa ataaaaccac gtatcatgtt
    44701 ttagtatggt gatgatgcca tatacatgat gcgtggttct ttgttatgtt gtcataatct
    44761 tggagcgata ttttaacgac gtttatgatt taagtacgtt tgtaccttat atagtaatgg
    44821 tttgataggc ttaataaagt caccgatata ctcttctaca tgtgcgttaa aacctttttt
    44881 gaattgttgg acgccatagt cttctgatga ctctgaatag tcaccggtaa taccataaaa
    44941 attatagcga tcaatatgat gcgctttagc aaacttaatc atttcccact gcaaatggta
    45001 ggcacccata taagcattat atttagggtt tgaaccacta gataagtaat aaacttcatg
    45061 ctcattgtag ataaataaag cagaagctaa gtttaagact gcaccatctt gttcaatttg
    45121 ttctattgta ttgtcgattt tacgcttatt gctatttagc tgttgttcta gctgtgtgcg
    45181 tttcgtttta tttttctttg aattaggact ttcttccaat gcttcttcaa cacctgagag
    45241 ttcagctgtt aattgttgtt gctttaattg taacgttttt aaatactcgt ttaaatcaat
    45301 atacgccaac tttaacatgg cgtggtcatc gtataacttt tgcatttctt caaagtatgg
    45361 taactcacgg aatttgaaac cgtgcttttc ctcagccata tggaataagt cgaaaaaagt
    45421 ttgcgtttca tcaatcgtta acgttttagt tttgacacca atatcatatg tttttttaat
    45481 attacgtctc gtttgataat ccatttcttt taaaagttgg tcttcagtct tatcttttaa
    45541 atctaacact gacagccaac ggatttggct cattgaatca taacctacag ggaaaccttg
    45601 gtgtttataa cctaatttat ccattgttct aacaaatgct cggttatcat aagatttaac
    45661 aatttcaccg tctgcattgc gtaaattttc aattaaatat ggatctacaa ggacatataa
    45721 acaattgtgt ttctttaaat atgacgttaa tgctttaaag aaaaatgcta ctaatgattg
    45781 atttgtataa tccatcactg gcccgcgatg tgtataaaaa tatttgaaaa atttaagtgt
    45841 gcgtgcttct gtcaataagc atcctgcaat cacttgacca ttgtcatctt taacccctac
    45901 aagatgcaca tcgcctttta aatcaactct atgattgtaa tgaatagctg attgtgtgta
    45961 atgtgaaaaa tgctttgttg taaacgcatt gaactcatcc gaagtcaacg ttacaaagtt
    46021 cattttatcc catccctctc tgaattgaac tgtaattttt gaatttatta ataatgctat
    46081 ttttttattt tatcaaaaac tgattacaaa tacacataga aaatgaaata tatttttctt
    46141 tgactataca taactgttat ttctttggat atttatatta aatgcattgg tagtagttgt
    46201 agcgcattaa tgtttgacgg tgtatagtat taattatatt gaaagttagt tggaagttga
    46261 tagtaggagt gggagcattg aagcgatttg tggcgacggt attattatta ctagtcttta
    46321 tatcaggatg tggtaatgat aaatatgtga aagaaataga tgaagcagtt aaaattcaaa
    46381 atcaaaaaca agaacaactt gccaaaaaag gcaacggtga tcgtgttgat cattttgaac
    46441 gcaaagatgc taatatttat gtctatgata aggataaaat tatcatttta gcttataaac
    46501 ctttgagtaa tgatgatgaa gtgcattatt atgcatatga ttttagtgat aaacgtgtat
    46561 catataagca agattttgat tcgagacgat attatcaaca acatgatgcg gattatcatg
    46621 aagaaaatat gacgaactag atatgaacag gagttattat gactaaaaaa ttactaacat
    46681 tatttatagt gagcatgtta attttaacag cttgcggtaa aaaagaatca gcaacgacat
    46741 cctcgaaaaa cggcaaacca ttagttgtca tatatggcga ctataaatgt ccttattgta
    46801 aagaattaga tgaaaaagtc atgccaaagt tgcgtaaaaa ttatatagat aatcacaaag
    46861 tggaatacca atttgtcaat ttagctttct taggtaaaga ctcaattgtt ggttcgcgtg
    46921 cgagtcatgc agtattgatg tatgcaccta aatcattttt agattttcaa aagcaattat
    46981 ttgctgccca gcaagatgaa aataaagaat ggttaacaaa agaactatta gataaacata
    47041 ttaaacaact gcatttagat aaagagacgg aaaataaaat tataaaagat tacaagacaa
    47101 aagatagcaa gtcttggaaa gctgcagaga aagataaaaa aatagcgaaa gataatcata
    47161 taaaaacgac accaactgca tttattaatg gcgagaaagt tgaagatcca tatgattatg
    47221 aaagttatga gaagttatta aaagataaaa taaaatagtc ttaattgttg agataagtaa
    47281 gtgatatcaa tttattagga caatatgaaa aggcaatttc tattagcgat atgatagaga
    47341 ttgtcttttt aatgtatgaa gtctaaatag gtagaaatta tcatgtaaac attgtttagt
    47401 agggaatcag tacaggatag gtattgattc ttccccgtgc gaaatcttga ttagtagttt
    47461 ttttctgtgt cgcttgtttt attgtacaga tatttgtaca attgaggtgt gttaaaagga
    47521 ggcgataaat atgattatta aaaattattc atacgctcga cagaatttaa aggcacttat
    47581 gacaaaagta aatgatgata gtgatatggt aactgtaaca tctactgatg ataaaaacgt
    47641 agtaatcatg tcagaatcag attataactc catgatggaa acactttacc tccaacagaa
    47701 cccaaataat gctgaacact tagctcaatc aattgcagat ctagaacgtg ggaaaactat
    47761 aacgaaagat atagatgtat aatggctagg ttaaatatta cgttttcgcc tcaagccttt
    47821 gaagattata agtattttca gcagaacaat aaaaaaatgg tgaagaagat taatgagtta
    47881 cttaaaagta ttgacagaaa tggtgcattg gaaggtatag gtaagcctga aaagttaaaa
    47941 tcgaatctga ctgggtatta tagtagacgt atcaatcacg aacatagatt ggtttataca
    48001 gtagatgaca atcatataaa aatagcatca tgtaaatacc attattaaat ataaaagtca
    48061 cactataaaa atagggtaag ttattttagg acaatatgaa aaggcaattt ctattagcaa
    48121 tatgatagag attgtctttt tttcttatat tatgacgttc gtaaatacta taaagttttc
    48181 tgtatcatat ttgtacaata gtcatgtatt agataaaacg aaaagtggta aatacctaaa
    48241 gtatgattcg actttatatt atttataaaa acagtgcttg tattttaagt agcatgagta
    48301 tataatttta aaacgtaaag attactattt aggagggtga ctatgaaaaa gaaattaggt
    48361 atgttacttc ttgtaccagc cgtaacttta tcattagccg catgtgggaa tgatgatgga
    48421 aaagataaag atggcaaggt aacaattaaa acgacagttt atccattgca atcatttgca
    48481 gagcaaattg gtggaaaaca cgtgaaggta tcatcaatct atccagcagg gacagattta
    48541 catagctatg aaccaacaca aaaagatata ttaagtgcaa gcaagtcaga cttgtttatg
    48601 tatacagggg ataatttaga tccggttgct aagaaagttg catctactat caaagataaa
    48661 gataaaaaac ggtctttaga ggataaatta gataaagcaa agcttttaac tgatcaacac
    48721 gagcatggtg aagagcatga acatgagggg catgatcatg agaaagaaga acatcatcat
    48781 catggtggat atgatccaca cgtatggtta gatcctaaaa ttaaccaaac tttcgctaaa
    48841 gaaattaaag atgaattagt gaaaaaagat ccaaaacata aagatgacta tgagaaaaac
    48901 tacaaaaaat taaacgacga tcttaagaaa attgataacg atatgaagca agttacaaaa
    48961 gataagcaag gtaatgcagt atttatttca catgaatcaa ttggatactt agctgatcgt
    49021 tatggttttg ttcaaaaagg tattcaaaat atgaatgctg aagatccatc acaaaaagaa
    49081 ttaactaaaa ttgttaaaga aattagagat agcaatgcta aatatattct ttacgaagat
    49141 aatgttgcga ataaagtgac tgaaacaatt cgtaaagaaa cagatgcgaa gcctttaaaa
    49201 ttctacaaca tggagtcttt aaataaagaa caacagaaaa aagataatat tacgtatcaa
    49261 tcattaatga aatcgaatat tgaaaatatc ggtaaagctt tagacagtgg tgttaaagtg
    49321 aaagacgaca aagctgaaag taaacacgat aaagcaattt ctgatgggta ttttaaagat
    49381 gagcaagtta aagaccgtga attaagcgat tatgctggtg aatggcaatc tgtttaccct
    49441 tacttaaaag acggtacgct tgatgaagtg atggaacata aagctgaaaa tgatccgaag
    49501 aaatctgcta aagatttaaa agcttattat gacaaaggat ataaaactga tattactaac
    49561 attgatataa aaggaaatga aattacattt actaaagatg gtaagaaaca cactggtaaa
    49621 tatgaataca atggtaagaa aacattgaaa tatcctaaag gtaaccgtgg cgtgagattt
    49681 atgtttaaat tggtcgatgg taatgataaa gacttaccga aattcatcca atttagcgat
    49741 cacaacattg cacctaaaaa ggcagaacac ttccatatct ttatgggtaa tgataatgac
    49801 gcgttattaa aagaaatgga taactggcca acatattatc cttcaaaatt aaataaagac
    49861 caaatcaaag aagaaatgtt agcacattaa ttcaacaggt ttgcacactc tactcaactg
    49921 ttaatagctg aatagagtgt gttttttatt tcgtagttat caatttcaac agagggaatg
    49981 attaatatta ctatagttta taacaaatgg tttggtaaca tatgttactc aatgcatgtt
    50041 aagatgagta aatataaaag atagggagtg ggaagatgac gattaaagtt gaagataata
    50101 aaattatttt ttcaagaacg atagaagcac cgattgaaaa ggtgtttgat gcctatacga
    50161 caaaagaatt atttgaaaaa tggtttcatc caaaaggggc tagcacaaaa gtatttcgct
    50221 ttaatgctgt ttcaggcggt gatgcatttt atgcgattaa aacacctaca atgaccagct
    50281 atacattagc agaatataaa acggttaagc gtccatattt aattgaatat attgactcat
    50341 ttgcgacacc tcaaggtgca aaagatacaa aaatgccaag catgaaaatt actttgtcat
    50401 tttccaagag caatacaacg aaaacgacag tgacatcaac atcggtattt ccaacaaaag
    50461 aagccgctca acaagtcata aacatgggtg ttgaacaagg tatgaatcaa actttagatc
    50521 aacttgatgc tttattgaaa taaagttgtt gaaaatatgt aaaaactttt ttgtttcatt
    50581 cggtttataa taatcttgta atattataaa aatgagggat gattcgatgg tagaacgtta
    50641 tatcaaagtt ttaatattat atattttcac aacactacta tcttctattt cagtaacgtc
    50701 aaaatgtgta cctaataaag ttataaggtt tattttacgt actgcaattg gttacagtat
    50761 atttgcatat ggtttacatt acttttcaaa tttaaaaaag aataagtaat actttacata
    50821 aagcgagata aaatgagcgt cgtaatatct taaatcataa agatattagc caatcacgcg
    50881 atttatctcg ctgtttttat gaaagaaaac tacatttttg agagaataaa aagatttttc
    50941 tgaaatttaa tctatcaatt acattgattt actaatataa ttagaaagta aattttattt
    51001 gatcaaagta aatgggggaa gtactgtgat agaaaataag aaaacagttg aagatacata
    51061 ttcaacaggc gcaattgttg attcaatatc atcttcagta caaatgaagc aagtaatggt
    51121 acagcaaaca cctggccgat atatgcttaa agcaatgatg gccggatttt tactctcaat
    51181 cgttactgta tttatgttcg gaataaagac gcagtttgcg aatactcacg tagatggact
    51241 tatcaattta atgggagcca ttgcgtttag tttaggtttg attttagttg tattaactaa
    51301 ctctgaatta ttaacaagta acttcatgta ctttacagta ggctggtatt ataaagtcgt
    51361 ttctgttaag aagatgactt ggattttatt atattgtttc ttaggaaata ttttaggtgg
    51421 gtttgtgtta tttttcttaa tgaaatttgc gcatgtcatg acacctgaaa tgacacaagc
    51481 tttaacagct ttagttcaga aaaagactgt tgattcaaca tggttgaata tttttacaaa
    51541 aggtattttc tgtaacttct ttattaatat tggtattttc atctctatgc aattcaaagg
    51601 cggcttaaca aaggcattct tcatagcttg tggtgtcgtg gtctttgtat acatgggata
    51661 tgagcacgtt gtgttcaatg caggtctata tgcaggtatg gtattcttta accttgatgc
    51721 agtttcatgg ttacatgttt taaaaaatat cgtttttgct ttcttaggta actttgtcgg
    51781 tggcggtatt tttgtaggtc tcgtttatgc tttcttaaat ggtaagcgta atcgtttaga
    51841 gcaacaataa ttaagatgta gtgattaaat agcgtaacaa tgaatcattc ttccaaacca
    51901 ttcatgaatt tgaatggttt ttttacgttg agagagtaat ttttaataag tttcatgaga
    51961 gtattggtgt attcagatga agcatacttt ctgacatgtg ataaatttat tgatacactt
    52021 tgatggatat ttattttaaa aataaaatat ggttaaatca tttaaaaaag agtggggatt
    52081 aatatgacaa aaacgatgat tcgactcgca agtgaacaag atgcagaaaa attgcaacaa
    52141 ctcatgcatg aagcatttac gcctctaaga gaactaggta ttgattggcc ttcagttaat
    52201 gctaatttag atgctgttaa agaaaatata gataaaaata ctacatttgt catgacaatt
    52261 gatgatgaaa ttatatctac gattacggtt agatatcctt ggggaagtgt gaaaagtatt
    52321 tcgggctatc cttttgtctg gtggtttgcg acaaatcctg agtatgaagg gaaaggctat
    52381 ggtagccaat tacttactta tgttgaagaa gcatttttgc gagatacgtt aaagtcagcg
    52441 gcagttactt taggtacatc tgcaagattg catccgtggt tacttaaaat ttatgaaaaa
    52501 agaggttatg aaatatacag cgaacatgaa aatgatgatg gcgatttagg tgtgatcatg
    52561 cgcaaagtat tgatacccga gcgctttgac gaaacaatat taggccaacc accattttaa
    52621 gataataata tacactacaa gcgaccgata tattgatgct tgctcaaata aatgttgagt
    52681 agggattcat atatcggtcg ctttttttga tttaacaaaa agggaaaatg tataaggaat
    52741 atgcatgact acaggcatca gggaattccc tgattttaca ttataatgtg attcttttca
    52801 caaaaacaaa atgatttggt atacaatacg tgtgaaaggg ttggtaaatg tgaatgggaa
    52861 tatcattgtt gcacatggca tgaggcacgg acgacagaat caagcgttag aagcatttat
    52921 ttctgaatta gtaaaagatg atatacatca ctatgatatt gcgtttttag aaagtgagca
    52981 tcaggattta gagacggtaa tgacgacgtt gattcaaagt ggggttgacc attttaaaat
    53041 tgtaccattg ctaatcttta gtgcaatgca ttatctcaag gatataccga atatcgttca
    53101 tgaaatgaaa cgacggtatc cagacataaa ggtagaagta agcgagccac ttggcacaca
    53161 tcctttaatg agacgattaa ttgaacaacg tatttgtgac gcattagcag gtgacgaaca
    53221 acaagttgga gttatggttg ttgcacacgg caatattaat ggaaatttta ctaaggcaca
    53281 cgaagagtta caaatatgcg ctcaacattt gcagattaat aaacctactt atgcgagaac
    53341 gctatatgga gagattagtt ttacacatga tttagaaagc atctcgaaac ggtatcaaaa
    53401 attgattgtc gtaccattat ttttatatga cggaagactt gttaacaaag tgaagcagca
    53461 aatgaatgac atggttatta atacagatat acacttcaca ccttcaatta acttcgaccc
    53521 aattttaaag caaatcatta acgatagatt agaaagctta atgattccga tgaaaatata
    53581 aaagcactaa cgaaaaatta ataccttttt ttgaaataaa tattatggag taaaggggca
    53641 tattttatgg caaagcaaaa actagtaatg attggtaacg gtatggcggg cattcgaaca
    53701 atcgaagaaa tattagagcg cgccaacgat ttatatgata ttacggtaat aggtaaagaa
    53761 ccttatccaa actataaccg catcatgctt tcaaatattt tacaaaataa aatgacagtt
    53821 gaagaaacaa ttatgaatcc atatgagtgg tatgaggaac atggtatcga gttaattacc
    53881 aatgatcctg taattgaagt agatagagca aatcaatcag ttactactgc aaatggtatt
    53941 gaagtatcat acgataaatt gatttttgcg acaggttcta aagcattcgt cattccagtt
    54001 ccaggttcga cattaccgag tgtaattggt tggagaacga ttgatgatac tgaacaaatg
    54061 atgaacattg cgaagactaa aaagaaagca attgtaattg gtggaggctt actaggttta
    54121 gagtgtgcac gtggtttatt agatcaaggt atggaagtaa cggtgttaca tttagctgaa
    54181 tggttgatgg aaatgcagct agaccgtaaa gcaggaaata tgcttaaagc agatttagaa
    54241 aagcaaggta tgaagtttga aatgcaagcc aacacaactg aaatcttagg agaagatgat
    54301 gttgaaggtg ttaaattggc tgatggacgc gagattccgg cagacttagt tgttatggca
    54361 gtaggtatac gaccatacac agaagtagcc aaagaatcag gtctagatgt taatcgtggt
    54421 attgttgtca atgatgtgat gcaaacaagt gatagcaatg tatatgcagt tggagaatgt
    54481 gcagaacata acggcaaagt ttatggactc gttgcaccac tatatgaaca aggtaaagta
    54541 ttagctgatc atttaacaaa taaagaaacg aacggataca agggatcaac aacatttacg
    54601 tcattaaaag tttctggttg tgacttgtat agtgctggtc aaattgtaga aaatgcagaa
    54661 attaaaggta ttgaaatatt taatagtgtt gataataact ataaaaaaat ctttttaaaa
    54721 gacggtaatg tagttggtgc agtactatat ggtgatatcg atgatggttc acgcttttat
    54781 aacatgatga aaaaaggtga atccactgaa gattacacac ttgtatcatt gcttactaaa
    54841 ggtggagaag aggcatcgct atcaattgct gatatggctg atgatgaaac aatttgtggt
    54901 tgtaatggtg ttgataaagg tactatagta aatgcgatta cggaaaatgg ctttacaaca
    54961 gttgaagaag taacggctaa aacaaaagcg gggaattcat gtggtaaatg taaaccgcaa
    55021 attgctcaaa tattgcagca caccttagga gatgactttg ttgccgcaaa acctgctggt
    55081 atatgtggtt gtactgattt gacacgcgat caaattgtaa cgcaaataag agcgaaaggt
    55141 ttaaaaacat ctaaagaagt tcgacatgtt ttaaacttta aaaataaagg tggatgtcca
    55201 aaatgtcgac cagcaatcaa ctattattta aacatggttt atccacatga tcatgaagat
    55261 gaaagagaat caagatttgc taacgaacgt taccatgcga atattcaaaa tgatggtaca
    55321 ttttctgtta tacctcaaat gcgtggaggt gttacagatg cagaccaact gattcgtcta
    55381 ggagaagtgg ctaagaaata tcatgtgcca ctagttaaag tgacaggttc gcaacgtgtt
    55441 ggtttgtatg gagttaaaaa agaagaatta ccaaatatat gggaagacct aggtatgcgt
    55501 tcagcatcag cttatggtaa gaaaacacgc tcagttaaaa gctgtgttgg taaagagttt
    55561 tgtcgatttg gtacgcaata cacgacacga cttggcattc gtttagaaaa aacatttgaa
    55621 tacatcgata cacctcataa attcaaaatg ggtgtatcag gctgcccaag aagttgtgtt
    55681 gaatcaggtg ttaaagattt tggtattatc tcagttgaaa atggattcca aatctatatc
    55741 ggtggtaatg gtggtacaga agtcgaaaaa gctgaatttt taacaactgt agaaacagaa
    55801 gatgaagtaa tcaaattatg tggtgctttg atgcaatatt atcgcgaaac aggtatatat
    55861 gctgaaagaa cagcgccatg gttaagaaga cttggatttg aaaatgtaaa agaagtctta
    55921 cttgacccag aaagacaaaa tgaactattt gaacgcatta tggatgctaa aaaagcagtc
    55981 gaagctgaac cttgggaagc aataactagc aatgcgcaag cacgtaaaat ttttgaagtg
    56041 gagaaggtgt aatacatgga aacaaaagaa aaaattaaag tgacaactat agatgaatta
    56101 acacccctaa ttggaaaaaa ggttattgtc aaaggcaaag aggtaggatt gtttttaact
    56161 gaaagtggta caattcacgc gattcacaat atttgtccgc ataaacaagg accattgtca
    56221 gagggaacag tgagtggtga atatgtattc tgtccacttc atgatcaaaa gattgattta
    56281 aatactggga ttgtacaaga acctgatgaa ggttgtgtag atgtttatga ggtagaagtt
    56341 acagacggga acgtatatat atgtctgtag ataaatatgg caaggtttac ttgataggtg
    56401 cgggaccagg taatccgaat tatttgacta aaaaggctga gcgtttaata cgtgaagcgg
    56461 atgttatact atatgatcga ttagtgaatc cgttaatttt acaatatgcg aatttgacta
    56521 ctgaaattat cgatgttggt aaaaagccgt atgcaaaaca cattcagcaa gaaaaaataa
    56581 atgaatgtat cgtggaagca gcacgtcgat ataacaaggt tgtgaggctt aaaggtggcg
    56641 acccagcaat atttggacga gttcaagaag aagttgacac actaaacaac tttaatattg
    56701 cgtttgaaat tgtacctggt gtgacatctg cgagtgctgc agttgctacg atgcaaacag
    56761 gattaacgat gcgtgctgtt gctaagagtg tgacattttc tacaggtcac tttaaagatt
    56821 cagaagaaaa tgaagtagat gtcaacgctt tagtaaatgg tggtacgttg gcgatatata
    56881 tgggagttaa acgtttaggg aaaattatcg cccagataca acagtacaca gatattgatt
    56941 atccgatagc gattgtcttt caagcatcgt gttttaacga gtttgttgtt aaggggcgtt
    57001 taagtaatat tgttgggaaa ctggagcatt acgcaattga ggcgaaacca ggtatatgta
    57061 ttataggcga agtagtgggt tatactgaaa atgtctcaac aacttctaat ccgactcagc
    57121 aattttatgt agtaagtggt tctagacatg acgcccttat gctctgtgaa catttatatg
    57181 acgaaggtta tggctgtttg ctaaacccaa atgatacatc gaatggcaca tatcattcgt
    57241 cgcaatatga ttactatgat gcatttatta agcagcaaga aaatgtaaca tatatttcaa
    57301 ccgatcgtgc agatgctaat acagtgttat gtcactaatt tataaaaaat aaatgaataa
    57361 gtaaggtttc aaccgagaga atatattcgt gttgaagcct tatttgtcgt tgtgccaaat
    57421 ttgaacgatt tagattggca ataagcacga ccatacatga ttgtgtatta tttcaatgaa
    57481 atcccgttat tgatagggaa attccttaag taattaggtg attccctaat attttatatt
    57541 tgtgaaaaaa tgtacaatct aattaaagca atagtcttgg gcattttaaa gtatttaaaa
    57601 acacgacatc tacacatcgt atttttatac gtaggaggat ataaatatgg gaaaatttgg
    57661 attgaatttc tttaagccaa cagaaaaatt taatgggaat tggtcgatcc tagaaagtaa
    57721 aagtagagaa tgggaaaaaa tgtacagaga acgttggagc cacgataaag aagtaagaac
    57781 aacacatggt gttaactgta caggctcatg ttcttggaaa gtatttgtga aaaatggtgt
    57841 gattacctgg gaaaatcaac aaactgacta tccaagttgt ggtccggata tgcctgaata
    57901 tgaaccgaga ggatgtccac gaggtgcgtc attctcttgg tatgaataca gtccgcttcg
    57961 aatcaaatat ccatatattc gtggaaaact ctgggattta tggactgaag cattagaaga
    58021 aaactatggt aatcgcgttg ctgcatgggc gtctattgtt gaaaatgaag acaaagccaa
    58081 acaatataag caagcccgag gtatgggagg gcacgtgcgt tcaaattgga aagacgttac
    58141 agagataatc gcagcacaat tactgtatac aataaaaaaa tatggtccag atcgaatcgc
    58201 aggatttaca cctattccag cgatgtcaat gattagttat gcagcaggtg ctcgattcat
    58261 caatttgctt ggtggtgaaa tgcttagttt ttatgactgg tatgcagatt taccacctgc
    58321 ctctccacaa atttggggag agcaaacaga tgtgcctgaa tcaagtgact ggtataacgc
    58381 atcatacatt attatgtggg gctctaatgt acctttaaca cgtactccgg atgcacattt
    58441 tatgacagaa gtccgctata aaggtacaaa agtcatttca gtagcaccag attacgcaga
    58501 aaatgtgaaa tttgcagata actggctagc accgaatcct ggttcagatg ctgcaattgc
    58561 tcaagcaatg acacatgtta ttttacaaga acattatgtt aatcaaccta atgaacgctt
    58621 tataaattac gctaaacaat atacagatat gccgtttctt atcatgctgg atgaagatga
    58681 aaatggatat aaagcgggtc gatttttaag agcgagtgac ttaggtcaaa caacagagca
    58741 aggcgaatgg aagccagtta ttcatgatgc aatcagcgat agtttagtag tacctaatgg
    58801 cacaatgggt caacgttggg aagaagataa gaagtggaac ttaaaactag aaacagaaga
    58861 tggttctaaa attaacccta cattatcaat ggcagaaggt ggatacgaat tagaaacaat
    58921 tcaattccca tactttgata gtgatggaga tgggatattc aatcgtccaa ttccaactcg
    58981 acaagtcact ttagcaaatg gtgacaaagt ccgtattgct acaatttttg acttaatggc
    59041 aagtcaatat ggcgtgcgtc gttttgatca taaattagaa tcaaaaggat acgacgatgc
    59101 agaatcaaaa tatacacctg cttggcaaga agccatttca ggcgtaaaac aaagtgttgt
    59161 cattcaagta gcgaaagaat ttgcgcaaaa cgctatcgat actgaagggc gttcaatgat
    59221 tatcatgggt gcgggtatta accattggtt taactcagat acgatttatc gttcaatctt
    59281 aaacttagtt atgttatgtg gctgtcaagg tgtgaatggt ggcggttggg ctcactatgt
    59341 gggacaagaa aaatgtcgtc cgattgaagg atggagtact gtcgcatttg cgaaagactg
    59401 gcaaggacca ccacgtttgc aaaatggaac aagttggttc tattttgcaa cagaccaatg
    59461 gaaatatgaa gagtcaaatg tagatcgttt aaaatctcca ttagctaaaa cagaggattt
    59521 aaagcatcaa cacccagctg attataatgt tttagcagct agacttggtt ggttaccatc
    59581 atatccacaa tttaataaaa atagtttgtt gtttgcagaa gaagctaaag atgaaggcat
    59641 tgagtcgaat gaggcaattt taaaacgagc gataaatgaa gttaagtcaa aacaaacgca
    59701 atttgcgata gaagatccgg atttgaaaaa gaatcatccg aaatcactgt ttatatggcg
    59761 ctcaaatcta atctcaagtt ctgcaaaagg tcaagaatac tttatgaagc atttacttgg
    59821 cacaaaatca gggttattag ctacaccaaa tgaagatgaa aagccagaag aaattacgtg
    59881 gcgtgaggaa acaacaggga aattagattt agtcgtttct ttagatttca gaatgacagc
    59941 aacaccttta tattctgaca ttgttttgcc agcagcgact tggtatgaga agcatgattt
    60001 gtcatctaca gatatgcatc catatgtaca tccttttaat ccagctattg atccattatg
    60061 ggaatcgcgt tcagactggg atatttataa aacgttggca aaagcatttt cagaaatggc
    60121 aaaagactat ttacctggaa cgtttaaaga tgttgtgaca actccactta gtcatgatac
    60181 aaagcaagaa atttcaacac catacggcgt agtgaaagat tggtcgaagg gtgaaattga
    60241 agcggtacct ggacgtacaa tgcctaactt tgcaattgta gaacgcgact acactaaaat
    60301 ttacgacaaa tatgtcacgc ttggtcctgt acttgaaaaa gggaaagttg gagcacatgg
    60361 tgtaagtttc ggtgtcagtg aacaatatga agaattaaaa agtatgttag gtacgtggag
    60421 tgatacaaat gatgattctg tgagagcgaa tcgtccgcgt attgatacag cacgtaatgt
    60481 agcagatgca atactaagta tttcatctgc tacgaatggt aaattatcac aaaaatcata
    60541 tgaagatctt gaagaacaaa ctggaatgcc gttaaaagat atttctagcg aacgtgctgc
    60601 tgagaaaatt tcgtttttaa atataacttc acaaccacga gaagtaatac cgacagcagt
    60661 attcccaggt tcaaataaac aaggtcgacg atattcacca tttacaacga atatagaacg
    60721 tctagtacct tttagaacat taacaggacg tcaaagttat tatgtggatc acgaagtttt
    60781 ccaacaattt ggggagagct taccagtata taaaccgaca ttgccgccaa tggtatttgg
    60841 gaatagagat aagaaaatta aaggtggtac agatgctttg gtactgcgtt atttaacgcc
    60901 tcatggaaaa tggaatatac actcaatgta tcaagataat aagcatatgt tgacactatt
    60961 tagaggtggt ccaacggttt ggatatcaaa tgaagatgct gaaaaacacg atatccaaga
    61021 taatgattgg ctagaagtgt ataaccgtaa tggtgttgta acggcaagag cagttatttc
    61081 gcatcgtatg cctaaaggta caatgtttat gtatcatgca caagataaac atattcaaac
    61141 gcctgggtca gaaattacag atacacgtgg tggttcacac aacgcgccga ctagaatcca
    61201 tttgaaacca acacaactag tcggaggata cgcacaaatt agttatcact ttaattatta
    61261 tggaccaatt gggaaccaaa gggatttata tgtagcagtt agaaagatga aggaggttaa
    61321 ttggcttgaa gattaaagcg caagttgcga tggtattaaa tttagataaa tgcataggat
    61381 gccatacgtg tagtgtgaca tgtaaaaaca cttggacaaa tcgtccaggt gctgagtaca
    61441 tgtggttcaa taacgtagaa acgaagccag gtgtagggta tccgaaacgt tgggaagacc
    61501 aagaacacta caaaggtggt tgggtactaa atcgtaaagg gaaacttgaa ttaaaatctg
    61561 gaagtagaat ttcaaaaatt gctttaggta aaatttttta taacccagat atgccattaa
    61621 taaaagatta ttatgaacca tggaactata attatgaaca tttaacaact gcgaaatcag
    61681 ggaagcattc gccagttgct agagcgtatt cagaaattac aggggataac attgaaattg
    61741 aatggggacc taactgggaa gatgacttag caggtggtca tgttacaggc ccaaaagatc
    61801 ctaacatcca aaaaatagaa gaagatatta aattccaatt tgacgaaact tttatgatgt
    61861 atttaccacg tttatgtgaa cattgcttga atccaagttg cgttgcatcg tgcccttcag
    61921 gtgctatgta taaacgtgat gaagatggca ttgtattagt tgatcaagac gcatgtcgtg
    61981 gatggcgtta ctgtatgaca ggttgtccat ataagaaagt ttacttcaat tggaaaacga
    62041 acaaagctga aaaatgtact ttctgtttcc cgagaatcga ggcgggtatg cctacggtat
    62101 gctctgaaac ttgtacagga cgtatgcgtt acttaggtgt tttattatat gatgcagatc
    62161 gagttcatga agcggcttca gcagtagacg agaaaggttt atacgaaaaa caattagata
    62221 tattcttaaa tccatttgac gaagaagtca ttgctcaagc tgaaaaagat ggtattggtt
    62281 atgattggat tgaagctgca caaaactctc caatttataa gttagcaatt gaatataaac
    62341 ttgcatttcc gttacatcct gaatttagaa cgatgccgat ggtttggtat tgcccaccac
    62401 ttagcccaat tatgagctat tttgaaggta aaaatacaac tcaaaatcca gatgcgattt
    62461 tcccagccat tgaagaaatg cgtttaccta ttgaatactt agctaatatt ttcactgcag
    62521 gagatacaga gccagtaaaa ggagccctac aacgtatggc aatgatgaga agttatatga
    62581 gatctcaagt tactcaacag ccatttgaca cgtctcgatt agagcgatta ggtataaccg
    62641 agcgccaaac taaagacatg tatcgtttat taggactagc taaatatgaa gatcgatttg
    62701 ttattccaac atcacacaaa gaaacctatt tagatacgta tcacgcacaa ggtagtacag
    62761 gatacaatta cggcggcgag cattttggag ataactgtga aggctgtggc gttgcagtag
    62821 gttcagggaa aactggtcaa gaaatttata atgagaattt ctatggaggg attttccgtg
    62881 attaatttcg ataattttaa aaaatatcaa gaaagttttg gatatatggc acaacagtta
    62941 tgttttccag aaaaattaac ttttcatcca aaaacttttg aagaaacaat ttcgaaagat
    63001 catccagcat atgaagattt agtagcattt agaaatgtaa tgatgacatt ttcattatca
    63061 gaaatcaaag cgatttatac agatacattt gattttacga aaaaagcacc attatatatg
    63121 acgtataaca aatttgatac gcaaaaagaa cgtgggcaaa tgttagctaa attaaaggta
    63181 ttatatgaaa tgtttggact agaaatggta gataatgaac tttctgatta tctaccgttg
    63241 atgcttcaat ttttgcaagt ggcagaatgg cgaaatgatc caagagctga agagaatatt
    63301 caattaatca ttatgattat tgaggatgga acatatgtga tggcgaatgc acttggtgaa
    63361 gataataatc catatgccta tgtgattcaa gcacttagaa aaacattgaa attatgtttg
    63421 acatcaccaa aaggagtgaa acatcatgct taatcagttt ttatgggtta tatttccgta
    63481 tttatgttta gttgtctttg tcgcaggtca tattgcacgt tatcgttatg ataaattttc
    63541 ttggacagct aaatctagtg aactaataga aagaaaaagg ttgatgtggg gaagtttatt
    63601 atttcactta ggtattattc cagtgttttt tggacacgta gttggattgt taataccgaa
    63661 atcatggatg gatgcagtgg gggtatctga gcatttatat catataggcg ctgtttatat
    63721 tggtagcatc tttggtataa taactttgat agggatgttt ttattaacag cgagacgtgt
    63781 tactacgaaa agtattcgaa gattaagttc agcgtcggat atatttgtaa atttcttatt
    63841 attacttatc gtatttatgg gatgttacgc aacattagta accaatatac aacatccaga
    63901 ttttaactac agaacttcat tatcaatttg gtttagacaa ttatttatgt taaaaccaga
    63961 tgcgtcattg atgagtggtg tgccgattgc atttaaaatg catatattgt taggtttcac
    64021 tattatggct tgttggccat ttacacgttt ggtacatgtt tggagtgtac ctttgacata
    64081 tataaatcgc agatatatta tttaccgtaa gaataaagtg taagcataag aggtgaaagg
    64141 atttgacacc agaagcaata attgaagatc gtagatttca agagacatta gataaaatac
    64201 gcaaagaaga gggttatgat tttgcggcaa tcgctttcta tgaatctaac aaaccatcat
    64261 ctccaataaa atggcactat gtttcaggta ataaaaataa tcgatttaaa ttgattattt
    64321 taagaaaagg tcgtggatta gctggaactg ttatgaaaac aggaaagcgt atggtaatag
    64381 ccaatgttgg tttagcttta gggcctgaag aaaagattga ctatccaatt ttattgagcg
    64441 aatcattaac agcagtttta gcagtgccgc tttggtataa gaatcaagtg tatggcgtac
    64501 tattatttgg tcaaagagat ggtcgtcctt taccaaaaat atttgataat gatgatattc
    64561 aacgtaagtt tggtattttc aatgatgata aataatgaga tgaattaggg tgtaagtcat
    64621 gattaatgag gacagtatac agttagatac tttattgaaa aaatattatg agcattcaat
    64681 cgaaaagata gtttttgctg atgataacgg caaaattatt gcaatgaatg atgctgctaa
    64741 agatatatta tctgaagaag ataattacag tgctgtggcg aatgcgattt gtcacagatg
    64801 tgaagggtat acaaatgcct atgatgtaca atcatgtaaa gactgtttct tagaatcgat
    64861 gcaagtacaa gctacgaatt tccaagtatt tatgaagacg aaagatcaaa aagtgatgcc
    64921 atttacagca acatatcagt tgattgatca agacagggga attcatgcat ttacgcttca
    64981 aaatgtttca tcacaaattg aacagcaaga gaaattacat caacaacgta tgatgcgtaa
    65041 aacaatctca gcccaagaaa atgaaagaaa gcgaatttct agagagttac atgatagtgt
    65101 gattcaagaa atgctcaatg tagatgttca attgagatta ttaaaatatc aagaagatac
    65161 aactaagctt ttggaagacg cagaaaatat tgaatatatt gtcgctaaat taattgatga
    65221 tatacgtaat atgtcggttg aattaagacc cgcttctttg gatgatctag gccttgaagc
    65281 agcttttaaa tcatatttta aacagtttga agaaaattat ggaataaaaa tcatatatac
    65341 atcaaatatt aaaaatactc gctttgatag tgatattgaa acggttgttt atcgagtagt
    65401 gcaagaagct attctaaatg cgttgaaata cgctgatgta aatgaaataa atgtaggtat
    65461 ccgtcaaact gggcgccatt tggtagcaga agtgatagat gcgggaaatg gttttgatcc
    65521 aagttctaag cctaaaggtt ctggactcgg tttatatgga atgaatgagc gagctgagtt
    65581 agtcagcggt agcgtcaata ttgaaacgaa aattggtgag ggtaccaatg ttacattgaa
    65641 cattccaatt tgaaacatac attgggggaa taaaattgaa aatagtcatt gccgatgatc
    65701 acgctgttgt ccgtacgggg ttctctatga ttttaaatta tcaaaatgat atggaagttg
    65761 ttgcaacggc tgcagatggc gtcgaagctt accaaaaagt aatggaatat aaacctgatg
    65821 tgttactaat ggatttaagt atgccaccag gtgagtcagg tcttatcgct acgagtaaaa
    65881 ttgctgacag ttttcctgaa actaaaatac taatattaac aatgtttgat gatgaggagt
    65941 atttgttcca tgtgttgcgt aatggtgcga aaggttacat attgaaaaat gcacctgatg
    66001 aacaattatt gttagctatt cgaactgtat ataaaggtga aacatatgta gatatgaaac
    66061 ttacaacatc tttagtgaat gaatttgtat ctaattcaaa tcaggacact gcaaacacaa
    66121 cagatccttt taaaatctta tcaaaacgag aactagaaat attgccactt attgccaaag
    66181 gttacgggaa taaagaaatt gcagagaaat tatttgtatc tgtgaaaaca gtagaagcac
    66241 ataagacgca tattatgaca aagcttggct taaagagtaa acctgagcta gttgaatatg
    66301 cattgaaaaa gaaattatta gagttttaga gtttgaaatt aatataattc agtataaaag
    66361 cgcgagagga aatgattatc ttctggcgct tttgtatgtt tcgaaatata tttttttata
    66421 aatcgaatgg aacctaatcc tttctccttt cggtaaccta tactaattcg ctttgcaaag
    66481 gtataacttt tattatagtt attgatttag agaataaatg attagttttc tactttgaac
    66541 aattatttta gttggtgtat tcagtgttgt agcatctgta tgaggattaa aaattgtcgc
    66601 tcttattcac attgctcaaa aaataattaa cagcttctga aatgtatgat gctaaatttt
    66661 gattatcata tgaattaaag taatctttga aacgcgtatc atcttcatat gttttagcaa
    66721 tacagcataa tgtttcatca tcaaaatcag cgatagtgtt cataaatgcc ttccactcaa
    66781 atacgagatc actacaatct tggattggat aatgactcaa agacatatga ttaaatttat
    66841 tgaagatagt tgtcaattta tgtctgatat cctgcgattg taagctgtct ttacgtctaa
    66901 taaatgattg atatgctttc gtatgaccat attttataga tgcttcttta tcatattgtg
    66961 actgtagtgt cttgtttaaa atgctggtat ctattagaga gagtccttta ataaattcac
    67021 atacagagcg tctaattaat tgtaagtcag aaatcttttt atctaacttg cttatttgct
    67081 ctgataataa ctttcgcaat tgttcattat catacgaaat gtattgtttt attttagcga
    67141 tatcaaaatc aaaagacttg agtattaaaa tcttttgtaa tttttctaag tcttgctgtt
    67201 tataaacgcg ataattttta tcatttttat ctggaactaa taatcctatt tcatcgtaat
    67261 aatgtaaagt tcttttagtt acacctgtaa tttcaataat atcttttaaa gtgtatgtgt
    67321 atgccaaaat tcagtcacct catttattat tttttgtgct ggaagtgttg tagcaacttc
    67381 aataggtatg tttgtttttt gtaaaaagta ttttaccaag tgatagccac atgcataccc
    67441 ggcagcatga gataggccaa cgataggcct accttgaagt ttattaatat catcaccata
    67501 gagataaggc atcgattcaa atatatgctt taaatgtaaa tgattataaa tagtattttt
    67561 aatttttacg ttatcacgac tccaattagt atttgttacc cacggtccaa tatgcgcttt
    67621 accatacaat gattctacat agttttcagc taatccttct gcaataatca attcaatcaa
    67681 acttccgcca tcccaatcaa tatatcgata gcgcatatta tgatttactt catgtgcaat
    67741 taagcttttc atagaattaa ttgtacttgt actcggcact aaataaatca taatataacc
    67801 tggtatgcca ccatcaccac cgcgattttt atttagatac ataagtggtt tttggctatc
    67861 tccaagtaat actgtgaaat gatagttaga aacttgagat gagatactat aatttgaaaa
    67921 ttgatctata gcaactttta aatatttttc gcaattactc cagaaatcat tattcaggta
    67981 ttgtattgac atttggtcag acatgcgtaa atctttggga gaaatttgaa aggcatctaa
    68041 aaattgaatc gcactcattg tctgtttgtc atcattataa ataggcatat gttgtacctc
    68101 aaatttcttt ttaaaaggta ctaatatttc tttagtgaaa attgaatcac ggtcgtttat
    68161 tggtgccttg agtatattct tatagacgga atctgatcta ataatattga ttttatacat
    68221 gataaacctc cttatgttgt cagcataaag gataacgtaa cgtgattttc aagcagtaat
    68281 tgtaactaat tgaaaaaaat aagaaaagta tgtgagtgtt cctaaataat atgattaaaa
    68341 tgatggcgaa taagtgtcta aaagcatctt aaagggacat tgtatagggt aaatcacttc
    68401 ataaataagg gaaaatcctt atgttcactt tttcacaatc ataataaaat atatatgtag
    68461 tcaatacttt gtctatattg aatgttttca tataaatgaa agcattttta aataacattg
    68521 acctctaata tataggcaga gtattgatat ctattaaaaa ataaatgatt ttgatgaagg
    68581 tgaaacgtat gtacaaaaca aaaggtggct ttcaacttac attacaaaca ttaagtttag
    68641 tggttgggtt tatggcttgg agtataattg cgccattaat gccctttatt aaacaagatg
    68701 tcaatgttac tgaaggtcaa atatcaatca ttttagcgat accagttatt ttgggatcag
    68761 tgctccgtgt gccatttggt tatttaacaa atattgttgg tgctaaatgg gtattcttta
    68821 caagttttat cgtattgtta ttcccgatat ttttcttaag ccaagcacaa acgccgggta
    68881 tgttaatggc atcaggattt ttccttggcg taggtggcgc aattttctct gttggtgtta
    68941 catcagttcc taaatatttc ccaaaagaaa aagtaggtct agcaaatggt atttatggta
    69001 tggggaatat cggtacagca gtttcttcat ttttagcacc accgatagcg ggtattattg
    69061 gttggcaaac aacagttaga agttacttaa ttattatcgc tttatttgca ttaattatgt
    69121 tcatttttgg tgacacacaa gaacgtaaaa ttaaagtgcc attaatggcc caaatgaaaa
    69181 cattatctaa aaactacaaa ttatattact taagttattg gtatttcatt acttttggtg
    69241 cttttgtagc atttggtatt ttcttaccta actacttagt aaatcatttt ggaattgaca
    69301 aagtagatgc tggtattcgt tcaggtgtat tcattgcgct ggcaacattc ttgagaccaa
    69361 taggtggtat actaggtgat aaatttaatg cagttaaagt actgatgatt gattttgtta
    69421 ttatgattat cggtgccgtt attttaggta tttcagacca tatcgcatta ttcactgtag
    69481 gctgtttaac aataagtatt tgtgcaggta ttggtaacgg cttaattttt aaattagtac
    69541 catcctactt ctcaaatgaa gcaggatcag caaatggtat cgtatcaatg atgggtggtt
    69601 taggaggatt cttcccaccg ttggtcatca catacgtagc taatttaaca ggttcaagcc
    69661 atttagcatt tattttctta gcggtatttg gatgcattgc attatttacc atgcgccatt
    69721 tatatcaaaa agaatatggt tcattgaaac acagttgata tgtaatacat gacattcatt
    69781 tagttaaata caaagcctta atatcatgca caatattcgt agcatgacat taaggcttta
    69841 gtagtgtatt cattttaaat ttaactatga aattggaata gatgttgatg aagtagtttc
    69901 attgcttggt ttgattttag gcaatgtaat ggttaataac ccattttcaa aactagcagt
    69961 aatatgttgc ttatcaacag cttcaaaatc aaattgacgc attaatgatt cgaagttacg
    70021 ctcatctaaa atgagttgtt cagatttgta ttttgcgctt ctagtagctt gaatagtgag
    70081 cgtattatta ttgaaatcga tactaatatc ttctttattt acacctgcta gttcagcttc
    70141 taagtaatat aattcgtctg tttcatatat attcgttaca aatgaaggtg ttgaaaagta
    70201 attaaatact tgtttaccta aatctttaaa tgtatcactt ggattaccgt taaaaaagtt
    70261 ttgattctcg aattgattga agttcaatat catcacttcc attatagaaa tttgtattac
    70321 aaagccatta tatgagtagt attaaaaaag ataaagtaaa aggggagata aaaaagttat
    70381 aaatgggtag atttgtgcct gataaggaat cagggcaaaa gaactgagca tcgagattta
    70441 tacaagcaat aaagataatg aataaacata gcgatgcata cttctgccca tcaccttatg
    70501 atagggagtt actttctgtc ggaatagtca aaatttttag aaacaaaatt ccgcaaatta
    70561 ttaattatat ctgatgcttc tcgttctgaa atgttgaatt cattaaagac cttaacagaa
    70621 atttcagcaa gagggctttt tattgcttta ccttgttctg ttagagaaat ttgtaggttt
    70681 ctttcatctt tctcttcacg tgttcgaaca acgtaatctt tcttttctaa tttctttagt
    70741 aatggtgtca gtgttccaga atctaagaat acacgttcac ctaatttttt gatgttaagt
    70801 ttttcatcat tttcaatcgc cattaaaaca atgtaaccag tataggttaa atcatattcc
    70861 ttaagatagt ttgtgtattt tttaattatt tcttttgaag aaacataaaa taaaaaacac
    70921 aactgcttgc taagatagct gttttctaca tacatccaat cactccttgt taaaataaac
    70981 aatattatga agtgtaatag ttgtcaagta ctgatttcat cgcaattatt gaattgtcta
    71041 taattgaatt taaatgttaa ataatgcaaa atatatcgat atcttagtat tttcatcggt
    71101 aattactgat atgactgatt ttttaaattg aaaaaaatgt aattgtatca tccttaattg
    71161 ttaaaagtag tcaattattt tgatagatag taaaataaaa tttgttatta aattttttaa
    71221 aagcatcgtg tatgtaattc gatttctata ataatattga gaataaaaaa attgttacaa
    71281 tctggtaaaa actctttatt aaataaattg attcgttcat actgaataga taagcaaaaa
    71341 ggagttacat aatgaagaag aaaaaaaacg cgattaaagt tatcattata ttatttattt
    71401 cattaattgt tgcagtagca tttttctttg gtctgaaaac atatcaaggc cataagaata
    71461 ttcaactaat tgacagttac ttggaagaga aaaatctaaa agataaaatt aaatcagaaa
    71521 aaacagagta tagtgctaaa aaaggtctct tctataagga agttacgttt aaagatgaac
    71581 ctggtgtaac ttatgttgtg caaccaatca gtactaataa aggattattt gttgaaggct
    71641 ttgatacaga gactaagaaa agtttgaaaa ctgcaaagca taaatatttc aatcaaaatt
    71701 ataaaccatc aaaatagtga aacgttaaac tggtgaaaca gtttagtgcc ttcaatttta
    71761 attatttgag gtaaacagtt tttgtatgga aattagtgat ttttgacatc tataaaagat
    71821 aaatatttta attttttata gataattatc aattttctga tataattgag tgatgtcaga
    71881 tgaaggggag tttgtactat ggctctattc aagagaaaaa ttagcctacc tatgcaagtt
    71941 gttattgcat tagtgttagg tgttgtcgta ggacttttat tatatggaca agaaaacgta
    72001 gcaaattaca ttaaaccatt tggtgacgta tttttaaatt taattaaaat gatcgttata
    72061 ccagttgtat tttgctcact agcgctttct atttcgaacg ttggggaatc gaaaactgta
    72121 gggcgttatg gctggaaaac aattttatac tttgaaatta ttacaacaat cgcaataggt
    72181 ttagggatta tcttcggtaa cctatttaaa ccaggtgctg gattagaccc aacaaaatta
    72241 cctaaaggtg atatttctaa atatcaatca actgcacatg cagcagaaca atctacatat
    72301 ggaaatcatt ttattgatac cattgtacat attattccga caaacttttt tgaagcttta
    72361 aataagggtg aattattacc tattatcttc ttcgcagtat tctttggatt aggattagct
    72421 gctgtaggta aaaaagcaga accagttaaa gaatttttaa gcggatcgct tgaagctgtg
    72481 ttctggatga ttaataaaat tttaaaatta gcaccacttg gagtgtttgc attcatttgt
    72541 actacaatta ttacatttgg tgcatccgca ttattaccac tattaaaatt agtattagtt
    72601 gttgtctttg caatggtgtt ctttgtattc gctatactag gactagttgc atggatgtgt
    72661 ggtattaata tcatgaatat tattagaatc ttgaaaagtg aattgctttt agcattttct
    72721 acatcaagtt cggaagctgt acttcctgta atgatgaaga aaatggaaaa cttcggttct
    72781 ccaaaagaaa ttacttcttt tgttatacca attggttata cgtttaactt agacggatca
    72841 gcactttatc aatctattgc agcattattc gttgcacaga tgtatggaat gcacttaaca
    72901 ttatcagagc aaattgtgtt gatgttaaca ttaatgatta cgtctaaagg tatggcggca
    72961 gtaccaggaa cttcaatcgt tgttttatta acaacattag gtgccatggg cttaccggca
    73021 caaggtttag cattaattat tggtgttgac cgtatcttag atatggtacg tacatgtgta
    73081 aacgttattg gtaacgcatt atcaacaatc gttatagcta aatgggaaaa cgtatatgac
    73141 aaagcaaaag gtcaagaata tttaaaatca atttaaaaaa tactatctga catttaaagc
    73201 cccttacaac ctttggttgt taggggcttt tatgcatgcg caaaagcgca ggcgaaccga
    73261 agcgcagtga cctcaggttg ttaggggctt ttatgcatgc gcaaaagcgc aggcgaaccg
    73321 aagcgcagtg acctcaggtt gttaggggct tttatgcatg cgcaaaagcg caggcgaacc
    73381 gaagcgcagt gacctcaggt tgttaggggc ttttatgcat gcgcaaaagc gcaggcgaac
    73441 cgaaaataga ctgacacagt aattcttaaa aagcagcagt aagataattt tcaattagaa
    73501 aacatcttac tgctgctttt aatatcttct atattactca aaattaaagc ttaattagtg
    73561 tttcatgtgc attttgccca tgtcatgaat tttcatcatt aaaccgtgag ggacgtcatc
    73621 atggtcaact tttttaactt taacaatttt atctgaatct gctaatttat aaacaattac
    73681 aaaatcacct tttttaactt taacatctga atctgaaggt aatttaacat ttttttcaat
    73741 actttcatct ttttcactaa tcattttttc aatagtagta ttatctttca taattccata
    73801 gtatgtatct ttctttccgc cagtcatcat catgattact aatacaatac atacaattaa
    73861 catgatggcg attaaactaa taccaagacc aaaacctttt ttctttttca tggttcatca
    73921 atctccttaa atgtagttaa ttctgttata cctaaaagtg caacagtttg caaatgcagt
    73981 atttatatta cataaaatta atttaaaaag acacacccta atcacgttaa atgtgaataa
    74041 agtgtgtcta aaaacaatac attgcaaatt ggattgtaaa catattaaac actttaatta
    74101 tagcgagtta ttttaagtat ttaacattgt tatatctaga attcataaaa gttatttcct
    74161 atatatactt tgtgttataa atcgattttg ataggtgtat ctaatgattt gtcattcatc
    74221 aatttaacag attgtggtgt cacctttaaa acacaaagtt ctgggtcttc ttttgaactg
    74281 aaaaagcttt tatcttgagt ctcccataac caatcgatta ctttttgatc agtaactact
    74341 tctatcgtgg cttccatttc aacgaaacta cgattagttg tgtcgttata gcctaacaaa
    74401 acatatgctg ctggattatc tttaatttct ttgaccttag cagaatggat attcgtttta
    74461 gtatataaag taagaccatc attataaaag accatatatc tactattagg tttgttatta
    74521 tatgcagttg ataatacacc aacttttgac gttgctaaca cgttttcaat tgcttgaatt
    74581 gcttgtgagt tactcattac atatcatctc cttatgatat aaatagcctt taacgtaaga
    74641 aactaaacac aagaggactg ttagtattta gcttggttta aagcaaatat atttaacctc
    74701 gtcgtgattt aacttgagtt caaatgtacg accagtttct tcttgaactg caagctccgt
    74761 tttagggtaa ttcgttttgt ctaattcatc taaaatttct ttttctatat aaacaagttg
    74821 atcgcttatt ggaagcaaat gttgaattga accatgttca tgattcaatg ttttaataat
    74881 catcaaagag tcttgaggta attcattatg gaaaatgaaa tcttgtttta cgtctgacat
    74941 atatcgatca ttaattttat tgaataataa gaaatggtag ttattatctt tacgactcaa
    75001 tacataatta tttgtaattt caatatcttc attaacaaaa ggtctaaaca ttttatataa
    75061 atgcattaat ggtagggggc taccatattt gttgtacaag gaaatataat ttgaatggtc
    75121 atctaataat tgatagctaa tgccaccgcc atatcgtaat aatgcgatta agtgatacac
    75181 tatgtcagat aattgaattg gattcttacc atcattagta tatttaaatc cgcttacaga
    75241 caggttatta tatacaaatt gtgttgatga tatacctgaa tctaaaataa atttcttata
    75301 ctgttcaaaa tgagtgtcag tttgatgata gtgttggttt ttagtgataa gatgtgttgc
    75361 agtttttgaa ttttcaatat caataaagta ataatggaat ttaagacgct gcatgacatc
    75421 ataaacttgt tccacggttg aataagtttc taaaaagcca tcgactgtca cactatattt
    75481 aatttcttta tttttgtttt taattttaag atgacataaa tgaatttctt ctgctgtcat
    75541 agaattagag caaaatacga gcataaattt aactaatttc ttgcttgtct tatagtcttg
    75601 attgccttgt aaaaatgtta gtattaactg cttcatcgtt tcgaattgtt gtgttgattt
    75661 aatagcgatt gctaaaccta tatttttttc gaaaagcttt tcaaaacatc tatttaacag
    75721 gttgtaattc gtttggctaa tctcaatatc gtgaatatcg tcaatgaaaa cgacaggttt
    75781 tggtaagtgc tcaaagttaa tatcgtaata ttcattgaaa ataaattgaa atagttcatt
    75841 gaaattacta aatcgaacaa atactttggc acgctgactt cgatctttcg gattaaaatc
    75901 atctatatga atatctgttg tatttgtagc cagttgagct gttaaatcaa ttgttgaaat
    75961 taactcagtg aattgtgata cgttatcttg ttggaagtgt atttgtggtg gttcagtaat
    76021 cttggaaacg agtgaacgga actgtttagg actaaaatgc aagtaattct taaattgatt
    76081 tgcaaaattt gtatgactgt taaaaccggc caattcagaa acagttgtaa tagaatgttt
    76141 tgtagaaagt aataaattga tggcgttaac aagtttaata cttgtaaaat aatctttaaa
    76201 attcatactc aaatatcgaa caaaaagatt agaacaatat gattcagaga tgttgcaatg
    76261 catcgctata tcttttaaag acaagtgcgc atcaatattg tcatgaatat agtttacaca
    76321 gtctatgaac accggattgc ttaaagcaat atttggtaaa tattcatgat ctattcttat
    76381 aaaagcttct ttaagtaaag tgtctataat actttgacct atatttttcc ccattaaaga
    76441 agaacttgtt ggtgtactga ttaaatcggc aattaatgac ttaatataat tacttgattg
    76501 taataaatga cgatctaaat aaccattaaa gaaatcatca tcttgttgat aaaaataaaa
    76561 aacgggtatc attaattcga ttatattttc gccgtggtta atattataaa tatcaccatg
    76621 gttaattaag ataatataat tacttacgtc tttggtttca ccattaatcg taatattgag
    76681 tttacttgta agtgaaaata gcaccataat attattaata tt
//
LOCUS       DAPDIM010000005        69398 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000005 DAPDIM010000000
VERSION     DAPDIM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 69398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69398
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.005"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            328..537
                     /locus_tag="RFE25_000345"
     CDS             328..537
                     /locus_tag="RFE25_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815445.1"
                     /translation="MKACLYLSNDKFVEIDNLEKVIKSGHRGTVEISKEKIKSSLFTN
                     GSYTFVGDKIVAIASAKIEFIEFID"
     gene            complement(527..670)
                     /locus_tag="RFE25_000346"
     CDS             complement(527..670)
                     /locus_tag="RFE25_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815446.1"
                     /translation="MLQKFRIAKEKSKLKLNLLKHANSNLETRNNPELLRAVAELLKE
                     INR"
     gene            complement(685..1128)
                     /locus_tag="RFE25_000347"
     CDS             complement(685..1128)
                     /locus_tag="RFE25_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815447.1"
                     /translation="MEQITLTKEELKEIIAKEVRNTIKGEKPISSGAIFSKVRINNDD
                     LEEINKKLNFAKDLSLGRLRKLNHPIPLKKYQHGFESIHQKAYVQDVHDHIRKLTLSI
                     FGVTLNSDLSESEYNLAAKVYREIKNYYLYIYEKRVSELTIDDFE"
     gene            complement(1141..1389)
                     /locus_tag="RFE25_000348"
     CDS             complement(1141..1389)
                     /locus_tag="RFE25_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2815448.1"
                     /translation="MYEFNVKRMKAERIAKGISISDMAKKLGMTPGTYSKKENGHIRI
                     NVDDLAKVIEVLELPQDKCGIFFTYRVSKMSTEQKQTS"
     gene            1553..1876
                     /locus_tag="RFE25_000349"
     CDS             1553..1876
                     /locus_tag="RFE25_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015978283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2815449.1"
                     /translation="MRTSAEIGKLIKQLRKENNVNLTDFATKIGVNKSTLSRYENGSR
                     KIPMEDIAEIANALKVTPEYLLLKNRQTENEVQHRAAHLEGELTDDEWQRVLDYADYI
                     RSKRK"
     gene            1889..2353
                     /locus_tag="RFE25_000350"
     CDS             1889..2353
                     /locus_tag="RFE25_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001642647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDU2815450.1"
                     /translation="MGLYEETLIQHDYIEIREADVLPDNLDGVWLGDLILIKRGLSDR
                     EKAGILFEELAHNKLTYGDIADYSNFNNRKFENYARRHGFISAVPLREIVEAHNYGVR
                     NLYELSEYLQLSEEYILEAIEQYKKIYGIGTHYGEFSITFEPLRVFKLHHID"
     gene            2385..3065
                     /locus_tag="RFE25_000351"
     CDS             2385..3065
                     /locus_tag="RFE25_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDU2815451.1"
                     /translation="MEENAPLETAVNNFKKIQNSEIYKFKYMNSWCLEYSEFLLDEVR
                     LLKENKSYTRYKKGTIIYVKLGVNVGREFSGNHFCMVLNNHDSNKNPILTVVPLTSSR
                     SKFNVHIEEDLLPLVLEKMDVTGKDLAKKIMNNLEKVSKAENPYDQKLLDENKSLNDD
                     FKKYSKVRKRYERFKYKKTYANVLNITTISKDRISKINRYDPAGEISYSKETVDKIEN
                     SIKIRFLS"
     gene            3272..4657
                     /locus_tag="RFE25_000352"
     CDS             3272..4657
                     /locus_tag="RFE25_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001657254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDU2815452.1"
                     /translation="MKVAIYTRVSTLEQKEKGHSIEEQERKLRAYSDINDWKIHKVYT
                     DAGYSGAKKDRPALQEMLNEIDNFDLVLVYKLDRLTRSVKDLLEILELFENKNVLFRS
                     ATEVYDTTSAMGRLFVTLVGAMAEWERTTIQERTAMGRRASARKGLAKTVPPFYYDRV
                     NDKFVPNEYKKVLRFAVEEAKKGTSLREITIKLNNSKYKAPLGKNWHRSVIGNALTSP
                     VARGHLVFGDIFVENTHEAIISEEEYEEIKLRISEKTNSTIVKHNAIFRSKLLCPNCN
                     QKLTLNTVKHTPKNKEVWYSKLYFCSNCKNTKNKNACNIDEGEVLKQFYNYLKQFDLT
                     SYKIENQPKEIEDVGIDIEKLRKERARCQTLFIEGMMDKDEAFPIISRIDKEIHEYEK
                     RKDNDKGKTFNYEKIKNFKYSLLNGWELMEDELKTEFIKMAIKNIHFEYVKGIKGKRQ
                     NSLKITGIEFY"
     gene            complement(4774..4947)
                     /gene="rpmF"
                     /locus_tag="RFE25_000353"
     CDS             complement(4774..4947)
                     /gene="rpmF"
                     /locus_tag="RFE25_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDU2815453.1"
                     /translation="MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCK
                     NCGSYNGEEVAAK"
     gene            complement(5027..5584)
                     /locus_tag="RFE25_000354"
     CDS             complement(5027..5584)
                     /locus_tag="RFE25_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDU2815454.1"
                     /translation="MKWSITQLRKYQGKPFEFDQTVSFDNLKESLDLIDLSPITIQGQ
                     LTIKSTEVVADIHITGTYTMPCARTLVPVKVPLDVTTTEVFDLEGYNQYNDDQDDVDE
                     HYHIIKDGMVNLQDIVEDIVIIEKPMRAYSEQSDQMLTVGNGWEVIDEDQLDELAKQQ
                     EQDDSESRQVDPRLQKLQQLYDKEQ"
     gene            5711..6850
                     /locus_tag="RFE25_000355"
     CDS             5711..6850
                     /locus_tag="RFE25_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDU2815455.1"
                     /translation="MKSVGLITEYNPFHNGHQYHINQSKKLTNADVTIAIMSGNFVMR
                     GEPAIYNKFTRAKMALSTADLVIELPATASLSSGDHFAELAVKVADYMSVDTIAFGSE
                     NNDIKTLKQLAHSINEIEQSESFSQKVKEGKSYPRIISELLEHHEALASPNNILGISY
                     LKAIAKNAKNINAISIKRENAQHHDSLIQHHQFASGTSIRTSIISQDDHWHHVVPKDI
                     QHLYVTPHITLNQIFPYLKYQIIAMTTDSLKNIYTVTEGFENRLKSNIYEATDFHHFV
                     KLLKTKRYTYTHIQRLLMNVLLNIKPTDVTSNIHAVKVLAMNDRGRQYLKHLKTAFPE
                     RQYITNINKSNAHYFTNEIKATHIYNAISGQQQTDFNTPVIQQYR"
     gene            complement(6912..7394)
                     /gene="coaD"
                     /locus_tag="RFE25_000356"
     CDS             complement(6912..7394)
                     /gene="coaD"
                     /locus_tag="RFE25_000356"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDU2815456.1"
                     /translation="MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKE
                     GTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELR
                     LTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
                     "
     gene            complement(7396..7938)
                     /gene="rsmD"
                     /locus_tag="RFE25_000357"
     CDS             complement(7396..7938)
                     /gene="rsmD"
                     /locus_tag="RFE25_000357"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002470236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDU2815457.1"
                     /translation="MRVIAGKHKSKALESMEGRNTRPTMDKVKEGIFNSLYDVSGIGL
                     DLFAGSGALGIEALSRGMDKVIFVDQNFKAVKVIKSNLANLDLEAQSEVYKNNADRAL
                     KALSKRDIQFDVIFLDPPYNKGLIDKALKLISEFNLLKENGIIVCEFSNHEEIDYQPF
                     NMIKRYHYGLTDTLLLEKGE"
     gene            8008..8397
                     /locus_tag="RFE25_000358"
     CDS             8008..8397
                     /locus_tag="RFE25_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815458.1"
                     /translation="MKQTFITLGEGLTDLFEFMTMIEYNHQRIDKIIYFHSPQAENKK
                     SSVAIIMNPTTGNHFQAFYIMINAIKYPYPDSNKKFQMINDCAEKFDIPILGIDVQPP
                     QAFHDLSLYYNYLISVLRLQKWIPELQ"
     gene            complement(8400..8654)
                     /locus_tag="RFE25_000359"
     CDS             complement(8400..8654)
                     /locus_tag="RFE25_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HDU2815459.1"
                     /translation="MNLIPRTSIVVYLKHMKHERQIRKYGHIVHSNRDRKFVIMYVNE
                     QDVDQIVHKLMQLKYVRHIDGSPYKYLKKTYEKEKHEIYN"
     gene            8893..9819
                     /locus_tag="RFE25_000360"
     CDS             8893..9819
                     /locus_tag="RFE25_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDU2815460.1"
                     /translation="MKKVNRNILNAVLVGAGFLSSLLMINKNKVITKKQTIPAFFKGN
                     APYIFAHRGGMALRPEQTQLAFDYAKQLGVDGFETDVRLTKDQQLIVFHDATVDRTTN
                     GSGKVSAHTLAELKKLDAAYHFKDINGLTPYRGHAHTTILTFDELLKQYPDMYINVDL
                     KDAPESYEGSIAPQIMFDTIAENQAFDRVLVTSFYKEQIVRFNKIAQGSVAIGASQQE
                     VTEAFLKYHLLGGRYYQPLAQTFQMPTHFKGIDLTSSRFIKWLNDMNIIPGYYGVNSI
                     DLMNDLYQKGAHTIVTDRPDLAQQFKQTIPNK"
     gene            complement(9882..10316)
                     /locus_tag="RFE25_000361"
     CDS             complement(9882..10316)
                     /locus_tag="RFE25_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDU2815461.1"
                     /translation="MINEASLAILDDIDELADMIVASDIYASFEQAKQALENNDEAHL
                     LYQSFLKSKEKYDEVMRFGKYHPDYKKVMLETRQRKRAYEMLDVVMHYKAREMALQHL
                     IDEVVTKIAYAVSEHVKIETGNPFFQTSHSGCATGGSCNCSL"
     gene            complement(10332..11369)
                     /locus_tag="RFE25_000362"
     CDS             complement(10332..11369)
                     /locus_tag="RFE25_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499615.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HDU2815462.1"
                     /translation="MKKLIIRVVGVLFLVGFLIYLFYSPRLKFDVLENPNKGNKVNRS
                     EQVNKSNNHAENPKPKEGVGTWVGKDIKVLTSKFGQADRVYPFRDGYKNYVFKDKNSY
                     YIVSTKREEIVSVYATGEKVNVSPLKIGQHSAEIFNHTSINPEPSFKVDGKKYEFELS
                     DEDLKTQTLIKYGDIYAQVYSDQQSKKVLSVRFLTKEMLADIEPYQLNSNSTSEEHNK
                     RPVEQNPNQLISLYEVTNEMRKLKGLKPLKINSDLAHIASNNLYEATSNGSDSVEFTE
                     DALRGQLDKNHVTYKTTAQNVGYAFNDVPTLIHSWMNSDIHRSRLLNSKYDEMGGDVM
                     RDYYSLIFLEK"
     gene            complement(11696..12157)
                     /locus_tag="RFE25_000363"
     CDS             complement(11696..12157)
                     /locus_tag="RFE25_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF420 domain-containing protein"
                     /protein_id="HDU2815463.1"
                     /translation="MGVPILPTISTTCIVISAILIAIGWRLIWKREINKHKNVMLAAA
                     VFALTFFLIYASRTIFIGNTAFGGPASIKKYYTIFLFFHINLATIGGILGLVQIITAF
                     KDKYNVHRKFGPFASVIWFCTAITGVAVYLLLYVLYPGGETTSLIKATFGH"
     gene            complement(12182..13093)
                     /locus_tag="RFE25_000364"
     CDS             complement(12182..13093)
                     /locus_tag="RFE25_000364"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HDU2815464.1"
                     /translation="MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVV
                     MTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITGQ
                     NLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPG
                     AVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKG
                     FKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWA
                     TQMFIYSLNYLVIFFVLAVIVSLLTLI"
     gene            13533..14444
                     /locus_tag="RFE25_000365"
     CDS             13533..14444
                     /locus_tag="RFE25_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme A synthase"
                     /protein_id="HDU2815465.1"
                     /translation="MFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLC
                     HGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFL
                     LLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKP
                     LRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMA
                     FIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFH
                     ALFITYLFGMTTYFIMLMLRSVRSDKQ"
     gene            complement(14584..18036)
                     /locus_tag="RFE25_000366"
     CDS             complement(14584..18036)
                     /locus_tag="RFE25_000366"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDU2815466.1"
                     /translation="MKQIKKLLVANRGEIAIRIFRAAAELDISTVAIYSNEDKSSLHR
                     YKADESYLVGSDLGPAESYLNIERIIDVAKQANVDAIHPGYGFLSENEQFARRCAEEG
                     IKFIGPHLEHLDMFGDKVKARTTAIKADLPVIPGTDGPIKSYELAKEFAEEAGFPLMI
                     KATSGGGGKGMRIVREESELEDAFHRAKSEAEKSFGNSEVYIERYIDNPKHIEVQVIG
                     DEHGNIVHLFERDCSVQRRHQKVVEVAPSVGLSPTLRQRICDAAIQLMENIKYVNAGT
                     VEFLVSGDEFFFIEVNPRVQVEHTITEMVTGIDIVKTQILVAAGADLFGEEINMPQQK
                     DITTLGYAIQCRITTEDPLNDFMPDTGTIIAYRSSGGFGVRLDAGDGFQGAEISPYYD
                     SLLVKLSTHAISFKQAEEKMVRSLREMRIRGVKTNIPFLINVMKNKKFTSGDYTTKFI
                     EETPELFDIQPSLDRGTKTLEYIGNVTINGFPNVEKRPKPDYELASIPTVSSSKIASF
                     SGTKQLLDEVGPKGVAEWVKKQDDVLLTDTTFRDAHQSLLATRVRTKDMINIASKTAD
                     VFKDGFSLEMWGGATFDVAYNFLKENPWERLERLRKAIPNVLFQMLLRASNAVGYKNY
                     PDNVIHKFVQESAKAGIDVFRIFDSLNWVDQMKVANEAVQEAGKISEGTICYTGDILN
                     PERSNIYTLEYYVKLAKELEREGFHILAIKDMAGLLKPKAAYELIGELKSAVDLPIHL
                     HTHDTSGNGLLTYKQAIDAGVDIIDTAVASMSGLTSQPSANSLYYALNGFPRHLRTDI
                     EGMESLSHYWSTVRTYYSDFESDIKSPNTEIYQHEMPGGQYSNLSQQAKSLGLGERFD
                     EVKDMYRRVNFLFGDIVKVTPSSKVVGDMALYMVQNDLDEQSVITDGYKLDFPESVVS
                     FFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRELLEEEQQGPVTE
                     QDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRNGETVEIEIDKGKRLIIKL
                     ETISEPDENGNRTIYYAMNGQARRIYIKDENVHTNANVKPKADKSNPSHIGAQMPGSV
                     TEVKVSVGETVKANQPLLITEAMKMETTIQAPFDGVIKQVTVNNGDTIATGDLLIEIE
                     KATD"
     gene            complement(18590..19816)
                     /gene="ftsW"
                     /locus_tag="RFE25_000367"
     CDS             complement(18590..19816)
                     /gene="ftsW"
                     /locus_tag="RFE25_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HDU2815467.1"
                     /translation="MKNFRSILRYIGKTSKFIDYPLLVTYIVLSLIGLVMVYSASMVT
                     ATKGTLTGGIDVPGTYFYNRQLAYVIMSFIIVFFIAFLMNVKLLSNIKVQKGMIITIV
                     SLLLLTLVIGKDINGSKSWINLGFMNLQASELLKIAIILYIPFMISKKMPRVLSKPKL
                     ILSPIVLALGCTFLVFLQKDVGQTLLILIILVAIIFYSGIGVNKVLRFGIPAVLGFLV
                     VFVIALMAGWLPSYLTARFSTLTDPFQFESGTGYHISNSLLAIGNGGVFGKGLGNSAM
                     KLGYLPEPHTDFIFAIICEELGLIGGLLVITLEFFIVYRAFQFANKTSSYFYKLVCVG
                     IATYFGSQTFVNIGGISATIPLTGVPLPFISFGGSSMISLSIAMGLLLIVGKQIKVDQ
                     QRKKQQQKVDIRRQFN"
     gene            complement(20130..20405)
                     /locus_tag="RFE25_000368"
     CDS             complement(20130..20405)
                     /locus_tag="RFE25_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HDU2815468.1"
                     /translation="MAKQATMKNAALKQLTKDADEILHLIKVQLDNLTLPSCPLYEEV
                     LDTQMFGLQKEVDFAVKLGLVDREDGKQIMLRLEKELSKLHEAFTLV"
     gene            20546..21028
                     /locus_tag="RFE25_000369"
     CDS             20546..21028
                     /locus_tag="RFE25_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815469.1"
                     /translation="MIQIKGAVKFPITLDSTTWIFDDRKVSIEDLEKGVFDGSKPIDF
                     EDNHEWNRAILEGQTNPPTLNSEIKYKKRAMLEGSFVINMTPFFKHSEPHDSATTIRL
                     SNEHDHLDIPIDLLPYLFFQFAKDGKRLYSDNGVDSFIYNQEDGYSYRINHVTHIEVI
                     "
     gene            21030..21197
                     /locus_tag="RFE25_000370"
     CDS             21030..21197
                     /locus_tag="RFE25_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaI family protein"
                     /protein_id="HDU2815470.1"
                     /translation="MRQVQCIICDAKVFIDERTTESKRLKNNPIRTFMCDDCKSRLDT
                     PKQRAQHYPLD"
     gene            complement(21337..23184)
                     /gene="typA"
                     /locus_tag="RFE25_000371"
     CDS             complement(21337..23184)
                     /gene="typA"
                     /locus_tag="RFE25_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDU2815471.1"
                     /translation="MTNKREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDER
                     AMDSNDIERERGITILAKNTAVDYKGTRINILDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEANDEQ
                     LEFPVVYASAVNGTASLDPEKQDDNLQSLYETIIDYVPAPIDNSDEPLQFQVALLDYN
                     DYVGRIGIGRVFRGKMRVGDNVSLIKLDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDL
                     IAVSGMEDINVGETVTPHDHQEALPVLRIDEPTLEMTFKVNNSPFAGREGDFVTARQI
                     QERLNQQLETDVSLKVSNTDSPDTWVVAGRGELHLSILIENMRREGYELQVSKPQVII
                     KEIDGVMCEPFERVQCEVPQENAGAVIESLGARKGEMVDMTTTDNGLTRLIFNVPARG
                     MIGYTTEFMSMTRGYGIINHTFEEFRPRIKAQIGGRRNGALISMDQGSASTYAILGLE
                     DRGVNFMEPGTEVYEGMIVGEHNRENDLTVNITKTKHQTNVRSATKDQTQTMNRPRIL
                     TLEEALQFINDDELVEVTPESIRLRKKILNKNVREKEAKRIKQMMQENE"
     gene            23286..23477
                     /locus_tag="RFE25_000372"
     CDS             23286..23477
                     /locus_tag="RFE25_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaF family protein"
                     /protein_id="HDU2815472.1"
                     /translation="MKQKKSKNIFWVFSILAVVFLVLFSFAVGASNVPMMILTFILLV
                     ATFGIGFTTKKKYRENDWL"
     gene            complement(23631..24458)
                     /locus_tag="RFE25_000373"
     CDS             complement(23631..24458)
                     /locus_tag="RFE25_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="HDU2815473.1"
                     /translation="MALYGFAQGLIQEAGIRIKQLMEQNLTIETKSNPNDLVTNVDKA
                     TEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISI
                     GIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLT
                     KPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYE
                     VNGQASNLLGEPLTISGPNSILVGNRGLHQEISNDYLEPYHDTLIQLHEQRFKRKSK"
     gene            24615..25229
                     /locus_tag="RFE25_000374"
     CDS             24615..25229
                     /locus_tag="RFE25_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YktB family protein"
                     /protein_id="HDU2815474.1"
                     /translation="MTKYTFKPKDFKAFNVEGLDARMEALNEYIRPQLHELGEYFSDF
                     FTSQTGETFYPHVAKHARRSVNPPKDTWVAFATSKRGYKMLPHFQIGMFEDQLFVMFG
                     IMHEAKDKATRAKVFERKFKAIQQLPDDYRVCLDHMKPDKPFIKDLTDDDLKEAIQRA
                     INVKKGEFFIARAITPQDKRLKSDKAFIAFLEETFDQFLPFYSA"
     gene            25411..26763
                     /locus_tag="RFE25_000375"
     CDS             25411..26763
                     /locus_tag="RFE25_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDU2815475.1"
                     /translation="MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVA
                     VGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRH
                     YLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
                     MKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIAL
                     GIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLL
                     VLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITG
                     TLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFL
                     SIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
                     "
     gene            complement(26842..27261)
                     /locus_tag="RFE25_000376"
     CDS             complement(26842..27261)
                     /locus_tag="RFE25_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDU2815476.1"
                     /translation="MNRKPELIMAWIANSISIIYLLVMGLSYFSLKSGNASQREELAK
                     QLSQNGGNVSLDMLQTTMGALAIILLISTLYGIFATICIKGRRKLSIILFVIAIIVSL
                     MALNLIAIVLWVIVMIMLISKKESKETTHKDDEYIYH"
     gene            complement(27544..28563)
                     /locus_tag="RFE25_000377"
     CDS             complement(27544..28563)
                     /locus_tag="RFE25_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDU2815477.1"
                     /translation="MTGEQFTQIKRPVSRLTEKVLGWLCWVMLLVLTVITMFIALVSF
                     SNNTSIANLENTLNNNAFIQQLLAGNGYNTTQFVIWLQNGIWAIIVYFIVCLLISFLA
                     LISMNIRILSGFLFLISAIVTIPLVLLIVTLIIPILFFIIAMMLFIRKDKVEMVAPQY
                     YEEYNGPIYDYREPVYERPQPKDDYYDVPKYEKELDKSNTVYDQEQERDKYDQFPKRA
                     VESEYNHDERTEEEPSVLSRQAKYKQKSTEELGIEDDGYYAEPEVDPKELKAQQKREK
                     AEIKAKKKEKRKAYNQRMKERRKNQPSAVSQRRMNFEERRQIYNNDISEERNSSEVKD
                     KKEQE"
     gene            complement(28637..29710)
                     /locus_tag="RFE25_000378"
     CDS             complement(28637..29710)
                     /locus_tag="RFE25_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDU2815478.1"
                     /translation="MKRFLQLIIGALVVGMLCLTLSHWFKSKEQVHTNQKIYVYNWGE
                     YIDPELIKKFEKETGIQVVYETFDSNEAMEAKIRNGGTHYDVAFPSEYTVQKLKRDHL
                     LLPIDHNKVPNIKNLDSDYMNMSFDKGNKYSLPYFFGTVGILYNKEKYPNESFDSWKS
                     LYNPKFKNQILLVDGAREIIGMSLNKLGYNLNDRNSHHLKEAERDLTKLAPQVRGVVG
                     DEITMMLQQNEGNIAVVWSGVAAPLVQEGDKYNYVIPKEGSNLWFDNMVIPKTAQNKE
                     GAYKFMNFLLDAKNNKQNTEFVGYATPNKAARQLLPKEIKDDHRFYPTKKEQERLEVY
                     KDLGPEVLSEYNENFLNFKMSLK"
     gene            complement(29710..30519)
                     /locus_tag="RFE25_000379"
     CDS             complement(29710..30519)
                     /locus_tag="RFE25_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815479.1"
                     /translation="MKWYGKLYIGILLAILYIPIFFLMFYSFNSAGNMIHFEHFTLEH
                     YQSLFQNDHLMSVIFNTIAVALLAASISTVIGTFGAIAIYYLRNKKFKVTLLTLNNVL
                     MVSSDVVIGASFLIMFTTIGHFTGLGLGFWTVLISHIAFCIPIVVIIVLPQLYEMNNN
                     MLNAARDLGATEPQLLSNIIIPNILPSIIGGFFMALTYSLDDFTVSFFVTGNGFSVLS
                     VEVYAMARKGISMEINAISTLLFAVIVLGILGYYLIQYVINKKKLIKRGVK"
     gene            complement(30525..31322)
                     /locus_tag="RFE25_000380"
     CDS             complement(30525..31322)
                     /locus_tag="RFE25_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815480.1"
                     /translation="MRNTNKFLLIPYLLWMVIFIIVPVVLLIYFSFLDINGHFSFTNY
                     QQIFTTKYLKMFAYSILYAALITIITLAISYPAAYYITHSKFQNILLMIMIIPTWINL
                     LLKTYAFIGLLSHDGVINQFFHLFNLPSFNLLFTTGAFLVVASYIYIPFMILPIFNSM
                     KAIPNNLLQASSDLGASPFYTFRKVIMPLTKEGVMTGIQVTFIPSLSLFMITRLIAGN
                     KVINIGTAIEEQFLTIQNYGMGSTIAIFLIVFMAFILIITKSSNGRG"
     gene            complement(31315..32409)
                     /locus_tag="RFE25_000381"
     CDS             complement(31315..32409)
                     /locus_tag="RFE25_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815481.1"
                     /translation="MEPLLSLKSVSKSYDDLNILDDIDIDIESGYFYTLLGPSGCGKT
                     TILKLIAGFEYPDSGEVIYQNKPIGNLPPNKRKVNTVFQDYALFPHLNVYDNIAFGLK
                     LKKLSKTEIDQKVTEALKLVKLSGYEKRNINEMSGGQKQRVAIARAIVNEPEILLLDE
                     SLSALDLKLRTEMQYELRELQSRLGITFIFVTHDQEEALALSDFLFVLKDGKIQQFGT
                     PTDIYDEPVNRFVADFIGESNIVEGRMVRDYVVNIYGQDFECVDMGIPENKKVEVVIR
                     PEDISLIKAEEGLFKATVDSMLFRGVHYEICCIDNKGYEWVIQTTKKAEVGSEVGLYF
                     DPEAIHIMVPGETEEEFDKRIESYEEVDNA"
     gene            complement(32422..32961)
                     /locus_tag="RFE25_000382"
     CDS             complement(32422..32961)
                     /locus_tag="RFE25_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2815482.1"
                     /translation="MNIGNKIKNLRRIKNLTQEELAERTDLSKGYISQIESEHASPSM
                     ETFLNIIEVLGTTPSEFFKDSENEKVLYKKEEQVIYDEYDEGYILNWLVSKSNEYDME
                     PLILTLKPGASYKNFNPSESDTFIYCMSGQITLNLGKEIYQAQEEDVLYFKARDNHRL
                     SNESNNETRILIVATASYL"
     gene            complement(33105..33380)
                     /locus_tag="RFE25_000383"
     CDS             complement(33105..33380)
                     /locus_tag="RFE25_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HDU2815483.1"
                     /translation="MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYK
                     RFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK"
     gene            complement(33548..34954)
                     /gene="lpdA"
                     /locus_tag="RFE25_000384"
     CDS             complement(33548..34954)
                     /gene="lpdA"
                     /locus_tag="RFE25_000384"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009383646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDU2815484.1"
                     /translation="MVVGDFPIETDTIVIGAGPGGYVAAIRAAQLGQKVTIVEKGNLG
                     GVCLNVGCIPSKALLHASHRFVEAQHSENLGVIAESVSLNFQKVQEFKSSVVNKLTGG
                     VEGLLKGNKVNIVKGEAYFVDNNSLRVMDEKSAQTYNFKNAIIATGSRPIEIPNFKFG
                     KRVIDSTGALNLQEVPGKLVVVGGGYIGSELGTAFANFGSEVTILEGAKDILGGFEKQ
                     MTQPVKKGMKEKGVEIVTEAMAKSAEETDNGVKVTYEAKGEEKTIEADYVLVTVGRRP
                     NTDELGLEELGVKFADRGLLEVDKQSRTSISNIYAIGDIVPGLPLAHKASYEAKVAAE
                     AIDGQAAEVDYIGMPAVCFTEPELATVGYSEAQAKEEGLAIKASKFPYAANGRALSLD
                     DTNGFVKLITLKEDDTLIGAQVVGTGASDIISELGLAIEAGMNAEDIALTIHAHPTLG
                     EMTMEAAEKAIGYPIHTM"
     gene            complement(34958..36250)
                     /locus_tag="RFE25_000385"
     CDS             complement(34958..36250)
                     /locus_tag="RFE25_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDU2815485.1"
                     /translation="MAFEFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKS
                     VVEIPSPVSGTVEEVMVEEGTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPAKE
                     EAPAEQAPVATQTEEVDENRTVKAMPSVRKYAREKGVNIKAVSGSGKNGRITKEDVDA
                     YLNGGAPTASNESAASATSEEVAETPAAPAAVSLEGDFPETTEKIPAMRRAIAKAMVN
                     SKHTAPHVTLMDEIDVQALWDHRKKFKEIAAEQGTKLTFLPYVVKALVSALKKYPALN
                     TSFNEEAGEIVHKHYWNIGIAADTDRGLLVPVVKHADRKSIFQISDEINELAVKARDG
                     KLTADEMKGATCTISNIGSAGGQWFTPVINHPEVAILGIGRIAQKPIVKDGEIVAAPV
                     LALSLSFDHRQIDGATGQNAMNHIKRLLNNPELLLMEG"
     gene            complement(36341..37318)
                     /locus_tag="RFE25_000386"
     CDS             complement(36341..37318)
                     /locus_tag="RFE25_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017637695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDU2815486.1"
                     /translation="MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGL
                     QKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTR
                     FRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLIS
                     SIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESM
                     KAAEALEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAE
                     LSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAKETLEF"
     gene            complement(37322..38434)
                     /gene="pdhA"
                     /locus_tag="RFE25_000387"
     CDS             complement(37322..38434)
                     /gene="pdhA"
                     /locus_tag="RFE25_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HDU2815487.1"
                     /translation="MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLT
                     DEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILP
                     GYRDVPQIIWHGLPLTEAFLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFAL
                     KKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAA
                     ETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMA
                     GDDPTRYRTSDEDAEWEKKDPLVRFRKFLENKGLWNEDKENEVIERAKADIKAAIKEA
                     DNTEKQTVTSLMEIMYEDMPQNLAEQYEIYKEKESK"
     gene            complement(38605..39231)
                     /locus_tag="RFE25_000388"
     CDS             complement(38605..39231)
                     /locus_tag="RFE25_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkyA family protein"
                     /protein_id="HDU2815488.1"
                     /translation="MKFGKTIAVVLASSVLLAGCTTDKKEIKAYLKQVDKIKDDEEPI
                     KTVGKKIAELDEKKKKLTEDVNSKDTAVRGKAVKDLIKNADDRLKEFEKEEDAIKKSE
                     QDFKKAKSHVDNIDNDVKRKEVKQLDDVLKEKYKLHGEYAKAYKKAVNSEKTLFKYLN
                     QNDATQQGVNEKSKAIEQNYKKLKEVSDKYTKVLNKVGKEKQDVDQFK"
     gene            39596..40147
                     /locus_tag="RFE25_000389"
     CDS             39596..40147
                     /locus_tag="RFE25_000389"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDU2815489.1"
                     /translation="MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNS
                     QDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQE
                     AYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLN
                     GVMFYDHIDKNHPLQPHTDAVEV"
     gene            40478..40600
                     /locus_tag="RFE25_000390"
     CDS             40478..40600
                     /locus_tag="RFE25_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815490.1"
                     /translation="MNDMMNLVINQIVIKLNYRDDWNEFIDIYSNTILLGLTIN"
     gene            40629..40847
                     /locus_tag="RFE25_000391"
     CDS             40629..40847
                     /locus_tag="RFE25_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HDU2815491.1"
                     /translation="MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFN
                     IEFITKLEGAHLDYEKENSEHFNVEIAK"
     gene            40847..42544
                     /locus_tag="RFE25_000392"
     CDS             40847..42544
                     /locus_tag="RFE25_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDU2815492.1"
                     /translation="MKQLHPNEVGVYALGGLGEIGKNTYAVEYKDEIVIIDAGIKFPD
                     DNLLGIDYVIPDYTYLVQNQDKIVGLFITHGHEDHIGGVPFLLKQLNIPIYGGPLALG
                     LIRNKLEEHHLLRTAKLNEINEDSVIKSKHFTISFYLTTHSIPETYGVIVDTPEGKVV
                     HTGDFKFDFTPVGKPANIAKMAQLGEEGVLCLLSDSTNSLVPDFTLSEREVGQNVDKI
                     FRNCKGRIIFATFASNIYRVQQAVEAAIKNNRKIVTFGRSMENNIKIGMELGYIKAPP
                     ETFIEPNKINTVPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPI
                     PGNTKSINRTINSLYKAGADVIHSKISNIHTSGHGSQGDQQLMLRLIKPKYFLPIHGE
                     YRMLKAHGETGVECGVEEDNVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDI
                     GNVVIRDRKLLSEEGLVIVVVSIDFNTNKLLSGPDIISRGFVYMRESGQLIYDAQRKI
                     KTDVISKLNQNKDIQWHQIKSSIIETLQPYLFEKTARKPMILPVIMKVNEQKESNNK"
     gene            complement(42790..43452)
                     /locus_tag="RFE25_000393"
     CDS             complement(42790..43452)
                     /locus_tag="RFE25_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDU2815493.1"
                     /translation="MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDI
                     ATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQN
                     DYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAG
                     QSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIA
                     TR"
     gene            complement(43585..44604)
                     /locus_tag="RFE25_000394"
     CDS             complement(43585..44604)
                     /locus_tag="RFE25_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDU2815494.1"
                     /translation="MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKI
                     NHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSF
                     YAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLS
                     PFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFL
                     SLRIQNSEHFYSAVFDYWWMFAISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFG
                     YGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYV
                     EGKKS"
     gene            complement(44601..45962)
                     /locus_tag="RFE25_000395"
     CDS             complement(44601..45962)
                     /locus_tag="RFE25_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HDU2815495.1"
                     /translation="MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKND
                     LQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAF
                     FFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKN
                     GKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKK
                     ALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDE
                     KTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCF
                     VISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGY
                     MRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGE
                     IEK"
     gene            46160..46393
                     /gene="nrdH"
                     /locus_tag="RFE25_000396"
     CDS             46160..46393
                     /gene="nrdH"
                     /locus_tag="RFE25_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDU2815496.1"
                     /translation="MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMI
                     DFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD"
     gene            complement(46630..48348)
                     /gene="ptsP"
                     /locus_tag="RFE25_000397"
     CDS             complement(46630..48348)
                     /gene="ptsP"
                     /locus_tag="RFE25_000397"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDU2815497.1"
                     /translation="MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAK
                     FNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANA
                     ATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVI
                     VGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGD
                     MIIVDGLNGDVIVNPTEDELIAYQDKRECYFADKKELQKLRDADTVTVDGVHAELAAN
                     IGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMDGKRVVVR
                     TLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMF
                     PMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDF
                     FSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMA
                     GDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIEL
                     VNNYVK"
     gene            complement(48351..48617)
                     /locus_tag="RFE25_000398"
     CDS             complement(48351..48617)
                     /locus_tag="RFE25_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HDU2815498.1"
                     /translation="MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNL
                     KSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK"
     gene            complement(48771..49313)
                     /locus_tag="RFE25_000399"
     CDS             complement(48771..49313)
                     /locus_tag="RFE25_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF697 domain-containing protein"
                     /protein_id="HDU2815499.1"
                     /translation="MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQR
                     AEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVK
                     ERIMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYF
                     MNKIGKDHIQKCENVIKNVM"
     gene            complement(49367..50539)
                     /locus_tag="RFE25_000400"
     CDS             complement(49367..50539)
                     /locus_tag="RFE25_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HDU2815500.1"
                     /translation="MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDK
                     SQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRL
                     FNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDS
                     EYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRGQYAKERHV
                     LNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDF
                     YKYAARHGHSYDTIVIDPPSFACNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNA
                     SVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH"
     gene            complement(50964..52259)
                     /locus_tag="RFE25_000401"
     CDS             complement(50964..52259)
                     /locus_tag="RFE25_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815501.1"
                     /translation="MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVD
                     THVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDY
                     DISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHF
                     MWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRR
                     ALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAK
                     RDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFV
                     SGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLT
                     EFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP"
     gene            52411..52545
                     /gene="graF"
                     /locus_tag="RFE25_000402"
     CDS             52411..52545
                     /gene="graF"
                     /locus_tag="RFE25_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance-associated protein GraF"
                     /protein_id="HDU2815502.1"
                     /translation="MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
                     "
     regulatory      53204..53304
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            53381..53956
                     /locus_tag="RFE25_000403"
     CDS             53381..53956
                     /locus_tag="RFE25_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDU2815503.1"
                     /translation="MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQL
                     TNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELV
                     FAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVA
                     GVLSYLLVKALDKTGVTKLFRPAAKEDYDNL"
     gene            53971..55371
                     /locus_tag="RFE25_000404"
     CDS             53971..55371
                     /locus_tag="RFE25_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815504.1"
                     /translation="MLKVSDLRLKYPNGQRKIFDHLNITIQDKEKVLLLGPSGCGKST
                     LLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVP
                     REDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAML
                     DVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQ
                     KYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGL
                     GEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQ
                     FITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVAT
                     ALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRL
                     KISDGALLDCDGDTNV"
     gene            55364..56170
                     /locus_tag="RFE25_000405"
     CDS             55364..56170
                     /locus_tag="RFE25_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDU2815505.1"
                     /translation="MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYIT
                     ILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTES
                     LVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLM
                     ISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRD
                     GPRTYYYNVPFSYKDIIFIIVLIAIITMAYYCSITLPITGIDDVRLDRVG"
     gene            complement(56437..57684)
                     /locus_tag="RFE25_000406"
     CDS             complement(56437..57684)
                     /locus_tag="RFE25_000406"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDU2815506.1"
                     /translation="MNVLVIGAGGREHALAYKLNQSNLVKQEFVIPGNEAMTPIAEVH
                     TEISESNHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEG
                     SKLFAKKIMKKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTI
                     EAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHD
                     EGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDG
                     PKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGY
                     PDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYEK
                     VSQIQSDHLFYRHDIANKALQLK"
     gene            complement(57706..59184)
                     /gene="purH"
                     /locus_tag="RFE25_000407"
     CDS             complement(57706..59184)
                     /gene="purH"
                     /locus_tag="RFE25_000407"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDU2815507.1"
                     /translation="MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVP
                     VRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLY
                     PFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRLRNDS
                     LDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIA
                     GAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAY
                     EADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEI
                     DMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPS
                     VKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVEL
                     AAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH"
     gene            complement(59199..59765)
                     /gene="purN"
                     /locus_tag="RFE25_000408"
     CDS             complement(59199..59765)
                     /gene="purN"
                     /locus_tag="RFE25_000408"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDU2815508.1"
                     /translation="MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFC
                     IDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASF
                     EGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRP
                     DDSKEQLEEKVKKLEYELYPSVIAKIVK"
     gene            complement(59768..60796)
                     /locus_tag="RFE25_000409"
     CDS             complement(59768..60796)
                     /locus_tag="RFE25_000409"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDU2815509.1"
                     /translation="MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGAT
                     FDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYF
                     LDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGA
                     VEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVF
                     LEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIF
                     DWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIVKNES
                     TAIELLGV"
     gene            complement(60789..62273)
                     /locus_tag="RFE25_000410"
     CDS             complement(60789..62273)
                     /locus_tag="RFE25_000410"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDU2815510.1"
                     /translation="MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIV
                     VSDQNELKGERGLGLLTEAINDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHF
                     YDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKES
                     LRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQ
                     DIHAGEYVVINDKGITVKSYTHHTTTAISTMEYIYFARPDSTIAGKNVHAVRKASGKK
                     LAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQ
                     GVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFP
                     SFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVE
                     SFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV"
     gene            complement(62252..64441)
                     /gene="purL"
                     /locus_tag="RFE25_000411"
     CDS             complement(62252..64441)
                     /gene="purL"
                     /locus_tag="RFE25_000411"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HDU2815511.1"
                     /translation="MSNFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTET
                     GIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNH
                     PSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGG
                     YGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKT
                     GRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGA
                     AGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGNEQKF
                     LDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNT
                     SKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTN
                     KAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIY
                     QQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDF
                     EPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGL
                     LSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNI
                     DNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD"
     gene            complement(64434..65105)
                     /gene="purQ"
                     /locus_tag="RFE25_000412"
     CDS             complement(64434..65105)
                     /gene="purQ"
                     /locus_tag="RFE25_000412"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase I"
                     /protein_id="HDU2815512.1"
                     /translation="MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGV
                     LIPGGFSFGDYLRSGAMASVAPIISEVKRLATEGKPVLGVCNGFQILTEIGLLPGALL
                     HNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANN
                     QIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSW
                     REQHV"
     gene            complement(65107..65370)
                     /gene="purS"
                     /locus_tag="RFE25_000413"
     CDS             complement(65107..65370)
                     /gene="purS"
                     /locus_tag="RFE25_000413"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HDU2815513.1"
                     /translation="MKTIELHITLQPQVLDTQGQTLTRAVHDLGYAQVNDIRVGKVLY
                     MTVDEVSDEKVHNIITTLSEKLFANTVIEEYSYKVLDDEKENA"
     gene            complement(65370..66074)
                     /locus_tag="RFE25_000414"
     CDS             complement(65370..66074)
                     /locus_tag="RFE25_000414"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDU2815514.1"
                     /translation="MTLLYEGKAKRIFSTNQENELRVEYKDEVTAGNGAKKDTMAGKG
                     RLNNQITSIIFKYLQENGIESHFIKQLSETEQLVKPVKIIPLEVVVRNIASGSITKRL
                     GFENGEVFREPLVEFFYKNDALNDPLITDDHVKLLNIASDEDIEILKSKALKINNVLK
                     QLMDAMNLKLVDFKIEFGKTETGQILLADEISPDTCRIWDKATNANFDKDVYRNNTGS
                     LIETYQIFLNKLEDLK"
     gene            complement(66078..67202)
                     /gene="purK"
                     /locus_tag="RFE25_000415"
     CDS             complement(66078..67202)
                     /gene="purK"
                     /locus_tag="RFE25_000415"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDU2815515.1"
                     /translation="MNFNKLKFGATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDC
                     PCRYVAHEFIQAKYDDEKALNQLGQKCDVITYEFENISAQQLKLLCEKYNIPQGYQAI
                     QLLQDRLTEKETLKSAGTKVVPFISVKESTDIDKAIETLGYPFIVKTRFGGYDGKGQV
                     LINNEKDLQEGFKLIETSECVAEKYLNIKKEVSLTVTRGNNNQITFFPLQENEHRNQI
                     LFKTIVPARIDKTAEAKEQVNKIIQSIHFIGTFTVEFFIDSNNQLYVNEIAPRPHNSG
                     HYSIEACDYSQFDTHILAVTGQSLPNSIELLKPAVMMNLLGKDLDLLENEFNEHPEWH
                     LHIYGKSGRKDSRKMGHMTVLTNDVNQTEQDMYAKFEGSN"
     gene            complement(67189..67671)
                     /gene="purE"
                     /locus_tag="RFE25_000416"
     CDS             complement(67189..67671)
                     /gene="purE"
                     /locus_tag="RFE25_000416"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDU2815516.1"
                     /translation="MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMM
                     VQFASEARERGINIIIAGAGGAAHLPGMVASLTTLPVIGVPIETKSLKGIDSLLSIVQ
                     MPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ
                     "
     gene            67872..68732
                     /gene="folD"
                     /locus_tag="RFE25_000417"
     CDS             67872..68732
                     /gene="folD"
                     /locus_tag="RFE25_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HDU2815517.1"
                     /translation="MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDG
                     ASQSYVRSKKKAAEKIGMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPK
                     QVSEQKILEAINPEKDVDGFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEAKN
                     AVVIGRSHIVGQPVSKLLLQKNASVTILHSRSKDMASYLKDADVIVSAVGKPSLVTKD
                     VVKEGAVIIDVGNTPDENGKLKGDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLL
                     AEKMRRGIDS"
BASE COUNT        22695 a        12561 c        10127 g        24015 t
ORIGIN      
        1 tataggttag taagtctaaa ttagaacatc gtttgttgtg ttccacagtc aactgagacg
       61 ttaacaaggt atgcgtacta gaaggtagta acttttagga cgctagactt tgatggaaaa
      121 cctaagcacc atacagggct ggggacgata ccagcaaaaa ttgtgctgtt agtcgtagtg
      181 attagaacca aacaaaattt ccgtaacaca taccttctac gacaaggtgt gtgttttttt
      241 attggaaaca aaatgtttgt aatgcttgca taatgtttat gcttatttcg tgtataatgt
      301 tgttatcaac ctaaggaggt gataagtatg aaagcttgtt tatatctttc taacgataaa
      361 tttgttgaaa tcgataattt agaaaaagtg ataaagtcag gtcatcgcgg aactgttgaa
      421 atatcaaaag aaaaaattaa aagttccttg ttcactaatg gctcatatac ttttgttgga
      481 gacaaaatag tagctatcgc ttcagctaaa atcgaattca tagaatttat cgattaatct
      541 ctttaagcaa ctctgcaact gctcgcaaca gttcagggtt gtttcttgtt tctaaattac
      601 tgtttgcatg ttttagtaaa ttaagtttta atttactttt ttctttcgcg attctaaatt
      661 tttgtaacat ttgttgttcc tcctttattc gaaatcatcg atagttaatt ctgaaactct
      721 cttttcatag atgtataaat aatagttttt gatttctcga taaacttttg ctgctaggtt
      781 gtattcactt tcactcaagt ctgaattaag tgtcactcca aaaattgata atgttaattt
      841 tctaatatgg tcatgaacat cttgtacata agctttttga tgaattgatt cgaagccatg
      901 ctgatacttt tttagcggaa tcggatgatt gagcttcctc aatcttccta gcgacaaatc
      961 ttttgcgaaa ttgagttttt tattgatttc ttctaaatcg tcattattga ttcttacttt
     1021 actgaaaatt gcacctgagc tgattggttt ctcgcctttt atagtatttc taacttcttt
     1081 cgctataatt tctttcaact cttctttggt taacgttatt tgttccatag tgtcctcctt
     1141 ttaagatgtt tgtttttgtt ctgttgacat tttggaaact ctataagtaa aaaaaatacc
     1201 gcacttatct tgtggcaatt ctagtacttc aattactttt gctaaatcgt caacattaat
     1261 tctaatatgc ccgttttctt tttttgaata agttcctggt gtcattccta atttttttgc
     1321 catatcagaa atcgaaatgc ctttagcaat gcgttcagct ttcattcttt tgacgttgaa
     1381 ctcatacatt tgctcacctc cgttttttga agttaactca atactaaacc taagtttcct
     1441 aattgtcaac aaaaatctcg aaaaatattt tttattcttt taaaatgcta gttgtttcct
     1501 atatggaaaa gtgttattat actgttataa ataaaacgga ggtaaatttg aaatgagaac
     1561 ttcagcggaa ataggtaaat taatcaaaca actacgaaaa gagaataatg tgaatttaac
     1621 tgattttgca actaagatag gtgtcaataa atctacctta tcccgatatg aaaacggtag
     1681 cagaaaaata cctatggagg atatagctga gattgccaat gcattgaaag ttaccccaga
     1741 atatttacta ttaaaaaata gacaaacaga aaacgaagta caacatcgtg cagctcattt
     1801 agaaggagaa ttaactgatg acgagtggca aagagtttta gattatgcag attatataag
     1861 aagtaaacgt aagtaaagga tgtatcagat gggattatat gaagaaactt taatacaaca
     1921 tgattatatt gaaataagag aggctgatgt acttccagat aatttagacg gggtatggtt
     1981 aggagattta attttaataa agcgtggttt atcagataga gaaaaagcag gaattctctt
     2041 cgaagaatta gcgcataata aacttacata cggtgatata gccgattact cgaatttcaa
     2101 caatcgcaag ttcgaaaatt acgcaagacg acacggcttt atctcagcag tcccgttacg
     2161 cgaaattgtg gaagcgcaca attacggtgt acgtaacttg tatgagttgt ctgagtatct
     2221 acaattaagt gaagaataca tattagaagc aatagaacaa tataaaaaga tatatggtat
     2281 tggtactcac tacggcgaat tctcaattac atttgagccg ttgagagttt ttaaattgca
     2341 tcatattgat taacagcgcc tatgtggcgt gaggaggatg agggatggaa gagaacgcac
     2401 ctttagaaac agcagttaat aattttaaaa agattcaaaa tagcgagatt tacaaattta
     2461 aatatatgaa ttcatggtgt cttgaatatt cagagttttt attggatgaa gttagattgt
     2521 taaaagaaaa caaaagttac accagatata aaaaaggcac tataatttat gtaaagttag
     2581 gtgttaatgt tggcagagag ttttctggaa accatttttg tatggtactt aataatcacg
     2641 attcaaataa aaatccaata ttaacggtag ttccacttac atcttccaga agtaaattca
     2701 atgtgcatat cgaagaagat ttgttacctt tagtattgga aaaaatggac gtaacgggta
     2761 aggatttagc taaaaaaatc atgaacaatc ttgaaaaggt gtcaaaagca gaaaacccat
     2821 acgatcaaaa attacttgat gaaaacaaat cgctgaatga cgacttcaaa aaatattcga
     2881 aggttcgcaa aagatatgag cgattcaagt ataaaaagac ctatgctaac gttttaaata
     2941 tcactacaat cagcaaggat agaatatcga aaattaatag gtatgaccct gccggagaaa
     3001 tatcatattc aaaagaaaca gtagataaaa ttgaaaatag tataaaaatt agatttctta
     3061 gttaaatcgc ttgaactaca ctctctttga tggtatatta catatataca aaacaagccg
     3121 ctgaaatatt tgcggcaagc ttcaaattag acaagtctct gaaatatttg cgacatgaga
     3181 gggtgcatct gcgctctctc tttttttata caattttcac gggtagcccg cctaccctta
     3241 ttattttttg ccaattttga ggagggagca catgaaagta gcaatttata ctagagtgag
     3301 tacacttgaa caaaaagaaa aaggacactc tatcgaagaa caagaaagaa aattaagagc
     3361 ttacagcgac ataaacgact ggaaaattca taaagtatat actgacgctg gatactccgg
     3421 agctaaaaaa gacagacccg ctttacaaga aatgttgaat gaaatagata attttgattt
     3481 ggttttagtc tataaactag atcgattaac tcgaagtgtt aaagacttac tagagatact
     3541 agaattgttt gagaataaaa acgtgttgtt taggagcgca acagaagtat atgacacaac
     3601 ttctgctatg ggacgtttgt tcgtaacatt agtaggtgct atggcagagt gggagcgtac
     3661 tacaattcaa gagcgtactg caatgggtcg acgcgcatca gctagaaaag ggttagctaa
     3721 aactgtccct cctttctatt acgacagagt aaacgataaa tttgtgccta atgaatataa
     3781 aaaagtatta cgatttgcag tagaagaagc gaaaaaaggt actagtttaa gagaaataac
     3841 tataaaattg aacaactcta aatacaaagc acccttaggt aaaaactggc acagatcagt
     3901 tataggcaat gctctaacga gtccggtagc tagaggtcat cttgttttcg gtgacatatt
     3961 cgtcgaaaac acccacgaag ctattataag tgaagaagaa tacgaagaaa taaaattaag
     4021 gataagtgaa aaaactaact ctacaatcgt aaaacataac gctattttca gaagtaaact
     4081 attatgtcca aactgtaacc agaaattgac tttaaacaca gtcaagcata cgcctaaaaa
     4141 taaagaagtt tggtattcta aactatactt ttgttctaac tgcaaaaata ctaaaaataa
     4201 aaatgcatgt aacatcgacg aaggcgaggt tttaaaacaa ttttacaatt atctaaaaca
     4261 atttgattta acatcatata aaatcgaaaa ccaacctaaa gaaatagaag atgtcggcat
     4321 cgatattgaa aagttgcgaa aagaacgcgc tagatgtcaa acacttttta tagaaggtat
     4381 gatggataag gatgaagctt ttccaataat aagtcgtatt gacaaagaaa tacatgagta
     4441 tgaaaagcgc aaggataatg ataagggtaa gacttttaac tatgagaaga ttaaaaattt
     4501 caagtattca ttgctaaacg gctgggaatt aatggaagat gagttaaaaa ctgaattcat
     4561 aaagatggca atcaaaaaca ttcattttga atatgtaaaa ggaattaaag ggaagcgcca
     4621 gaactcattg aagattacgg gtatagagtt ttattaattg gaagttcgga ataactatgc
     4681 agttacctcg ttcgccaatt atttttcgca atataaaaag tcccacttaa aacaatcatt
     4741 ttaagcggga ctttttatat tgagtaacta aaattattta gctgctactt cttcgccatt
     4801 gtaagaacca cagtttttac atacacggtg tgataatttg tattcgccac agtttgggca
     4861 ttcagtcata cctggtactg aaattttgaa atgcgtacga cgtttgtttt ttctagtttt
     4921 agaagttctt ctttttggta ctgccatgat atatcctcct tagattataa acgaaaaata
     4981 ctaaatgtta gtttaattaa caacattata tcattaatta aactacttat tgctctttat
     5041 catataattg ttgtaatttt tgaagccttg gatcaacttg tcgtgattct gaatcatctt
     5101 gttcttgctg tttagcaagc tcatctaatt gatcctcatc gattacttcc caaccattac
     5161 ctactgtcaa catttggtca ctttgctctg aataagctct cattggtttc tcaataataa
     5221 ctatatcctc gacaatatcc tgaagattaa ccataccatc tttaataatg tgatagtgtt
     5281 catctacatc atcttgatca tcgttatact gattgtaccc ttctaaatca aatacttctg
     5341 tagtagttac atctagtggg acttttactg gtacaagagt acgtgcacaa ggcattgtat
     5401 acgttccagt aatgtgaata tccgcaacga cttctgttga cttaatggtt aactgacctt
     5461 ggattgtaat tggagataaa tcaattaaat ctaatgattc ttttaaattg tcaaaactca
     5521 ccgtttgatc aaattcaaat ggcttacctt gatatttcct taattgcgta attgaccatt
     5581 tcatatggct tcacctctaa caagcacaaa atttatttta actttctaag aacaagttgt
     5641 caagattttt tcttaacata tcatgttctg ttacaatatt aataatgaat accgaaagga
     5701 cgaattgcaa atgaaaagcg ttggcttaat cacagaatat aatccctttc ataatgggca
     5761 tcaatatcat attaatcaat ctaaaaaact tacaaatgct gacgttacta ttgcaataat
     5821 gagtggtaac tttgtcatgc gtggcgaacc agcaatctat aataagttta ctcgtgcaaa
     5881 aatggcatta tcaacagctg atttagttat cgaactacca gcaactgcca gtttatcatc
     5941 tggcgatcat tttgccgaac tagcagttaa agtcgcagat tatatgagtg tcgatacaat
     6001 tgcatttggt agtgaaaata atgatatcaa aacattaaag caattagcac acagcattaa
     6061 tgaaattgaa caatctgaat ccttttcaca aaaagtaaaa gaaggtaaaa gctaccctcg
     6121 tatcattagc gaattattag agcatcatga agcactagca agtcctaaca acatacttgg
     6181 tattagttac ctgaaagcaa ttgctaaaaa tgctaaaaac atcaatgcaa tttctatcaa
     6241 acgagaaaat gctcaacatc atgattcatt aattcaacac catcagtttg caagtggtac
     6301 atctattaga acatcaatca ttagtcaaga tgatcattgg catcatgtgg tacctaaaga
     6361 tattcaacac ttgtacgtaa cacctcatat aacattaaat caaatatttc catatttgaa
     6421 atatcaaatc atagctatga ctacagattc attaaaaaat atttatactg ttactgaagg
     6481 ttttgaaaat cgtttgaaat ctaacattta tgaagcaact gattttcatc attttgtaaa
     6541 attactaaaa acaaagcgtt atacatatac gcatatccaa agactgttaa tgaatgtatt
     6601 attaaacatt aaacctacag atgttacgag taacattcac gcagttaaag tattagcgat
     6661 gaacgaccgt ggcagacaat atttaaagca tttaaaaaca gcgttcccag aaagacaata
     6721 tataaccaat attaacaaaa gcaatgcaca ttacttcaca aatgaaatca aagcaacaca
     6781 catatacaat gcaataagcg ggcaacaaca aacagatttc aacacgcctg tcatacagca
     6841 atatcgttaa caaatgaaaa cagtatttta ggattgtaaa ccatgataaa cctaaaatac
     6901 tgttattttt attacttaaa tttcttcttc aatgcctttt caacataagg tggaacgaat
     6961 tcagaaatat ctgctcgata agctgcaact tctttaacaa tacttgaact tataaatgaa
     7021 taattagtac tagacatcat atataacgtt tcaatttcat tgttcaactt tttattcatt
     7081 gaagttaagc gtaattcata ttcaaaatca ctgactgctc ttaaaccacg tatgattgtt
     7141 ttagctccta cttgttcaca ataatcgact agtaaaccac taaattgatg aaccttgaca
     7201 ttaggtaaat gtttaacaga ttgttcaatt aaatccatac gctcttctaa actaaacgta
     7261 ccttcttttt tactattttt aagaacacag acatgaattt catcaaatct atctgtactt
     7321 ctctcaataa tgtctaaatg accataagta atggggtcaa aactacccgg aatgaccgct
     7381 attgtatgtt ccatgctatt ctcccttttc taataacaat gtgtctgtca acccataatg
     7441 gtaacgttta atcatattaa acggttgata gtctatttct tcatgattgc taaattcaca
     7501 aacgatgata ccattttctt tcaataaatt aaactctgaa attagtttta aagctttatc
     7561 aatgagacct ttattataag gtggatctaa gaaaatgaca tcaaattgaa tatcacgttt
     7621 tgacaatgct tttaaagctc tatctgcatt atttttataa acttcagatt gtgcctctaa
     7681 atccaaattc gcaagatttg atttaataac ttttacagct ttaaaatttt gatcaacaaa
     7741 gattacctta tccatacctc gagagagtgc ttctattcca agcgccccgc ttcctgcaaa
     7801 taaatctaaa cctatacctg acacatcata taaactatta aagatacctt ctttaacttt
     7861 atccatagtt ggtctcgtat tacggccttc catactttct aaagctttac ttttatgttt
     7921 acctgcaatg acgcgcatgt tgttcacact tccaattcat ttagttattt aatataattt
     7981 attgagaaaa aggagaatga taaaccaatg aaacaaacat ttattacact tggtgaaggt
     8041 ctaacagatt tgttcgaatt catgacgatg attgaatata accatcaacg tattgataaa
     8101 attatctatt ttcattcacc acaagctgaa aataaaaagt catctgtagc aatcattatg
     8161 aaccctacaa ctggcaatca tttccaagca ttttatatca tgattaacgc tattaaatat
     8221 ccatatccag attcaaataa aaagtttcaa atgattaatg attgtgctga aaaattcgac
     8281 ataccaattt taggtatcga tgtacagccc cctcaagcat ttcatgattt atcgttatat
     8341 tataattatt taattagtgt gttaaggctc caaaaatgga taccagaact tcaataatat
     8401 taattatata tttcgtgttt ctctttttcg taagttttct ttaagtattt atatggtgag
     8461 ccatcaatgt gtctaacgta tttaagttgc attagtttat gtacaatttg atcaacatcc
     8521 tgctcattca catacataat tacaaattta cgatctctat ttgaatgaac gatatgtcca
     8581 tattttcgga tttgtcgttc atgtttcata tgttttaaat aaactacaat actagttctt
     8641 gggattaaat tcatttaaac ctcactccat ttattttcag cattaatcat atcatgtctt
     8701 tattaatttt aaaatattaa gctaccttaa ttatgtctta tgtaattgct cgataaatgt
     8761 atttagatta tattaaacat cattatatta attcaattct caagagcatc actatatgat
     8821 taaccacaca tttcgctgta gtcagaacta tgattttgtt aagctataaa agtaaacgag
     8881 gaggaatttt ctatgaaaaa agtaaacaga aacattttaa atgcggtact agtcggtgct
     8941 ggatttttaa gtagtctatt aatgatcaat aaaaataaag tgattactaa aaagcaaacc
     9001 atccctgctt ttttcaaagg caatgcacca tatatatttg cgcatcgcgg tggtatggct
     9061 ttaagaccag agcaaacgca acttgcattt gactatgcta aacaattagg cgttgatggc
     9121 tttgaaacag atgtgagact cacaaaagat caacagctta tcgtttttca tgacgcaact
     9181 gttgatagaa cgacgaacgg ctctggaaaa gttagtgccc acacattagc agaattaaag
     9241 aaattagacg cagcttatca cttcaaagat atcaatggac taacaccata tcgtggtcat
     9301 gcacacacaa ctatactaac cttcgatgag ttgctgaagc aatatcctga tatgtatata
     9361 aacgtagact taaaagatgc tcctgaatcc tatgaaggct caatcgcacc acaaattatg
     9421 tttgatacaa ttgcagaaaa tcaagcattt gaccgcgttc ttgtgacaag tttttataaa
     9481 gaacaaatcg ttcgttttaa taaaattgca caaggatccg tcgcaattgg tgctagccaa
     9541 caggaagtta cagaagcatt tttaaaatat catttattag gtggtaggta ctaccaacca
     9601 ttagcacaaa cgttccaaat gcctactcat tttaaaggca ttgatttgac ttcatctcgt
     9661 tttatcaaat ggttaaatga tatgaatatc attccaggct attatggcgt aaatagtata
     9721 gatctgatga atgatttata ccaaaaaggt gcacacacga ttgtgacaga tcgaccagat
     9781 ttagcacaac aattcaaaca aacaatcccg aataaataaa aacatcgagt cagatgctag
     9841 ttagtggttt caataaccac ctttttctga ctcgatgttt tttataatga acaattacag
     9901 gatccgcccg tcgcacaacc actatgtgat gtttgaaaga atggattacc tgtttctatt
     9961 ttgacatgct ctgaaacagc gtacgcaatt ttcgtaacaa cttcatcaat taaatgttga
    10021 agtgccattt ccctagcttt gtaatgcatc acaacgtcaa gcatctcata tgctcttttg
    10081 cgttgtcttg tctctaacat gactttctta taatcaggat gatatttccc gaaacgcatt
    10141 acttcatcat atttctcttt tgattttaaa aatgattgat aaagtaaatg tgcttcgtca
    10201 ttgttttcga gcgcctgttt agcttgctca aatgatgcat aaatatctga tgcaactatc
    10261 atatcagcta gttcatcaat atcatctaat atcgctagtg aagcttcatt aatcataaat
    10321 acccctcatt gttatttttc taagaaaatt agtgaataat aatctctcat tacatctcca
    10381 cccatctcat cgtattttga atttaataga cgagatcgat gtatatctga attcatccaa
    10441 ctatggatta atgttggtac atcattaaac gcataaccaa cattttgagc agttgtttta
    10501 taagtaacgt gatttttatc taattgccct cttaatgcgt cctctgtaaa ttcaacacta
    10561 tcagaaccat tagaggtcgc ttcatataag ttattagatg caatatgtgc taaatcgcta
    10621 ttgattttca atggttttaa tccttttaat tttctcattt cattcgttac ttcataaaga
    10681 gaaattaatt gatttggatt ttgctcaact ggacgcttat tatgctcttc tgacgtagaa
    10741 ttagaattta attgataagg ttcaatatct gctaacattt cttttgttaa aaatcgtaca
    10801 cttagcacct ttttcgattg ttgatcagaa tacacttgtg catatatgtc gccatattta
    10861 atcagtgttt gtgtttttaa atcttcatct gaaagttcaa attcatattt tttaccatca
    10921 actttaaagg aaggttctgg attaatactt gtatgattaa aaatttctgc agaatgttgt
    10981 cctattttta acggactaac attgactttc tcacctgtag catacactga aacgatttct
    11041 tcacgtttag ttgaaacaat gtaataactg tttttgtctt taaacacata atttttgtaa
    11101 ccatctctaa aagggtagac acgatctgct tgtccaaatt tagaagtaag cactttaata
    11161 tctttaccta cccatgtacc aacaccttct ttaggctttg gattttcagc atggttattt
    11221 gatttattca cctgttcaga tctatttact ttattacctt tattcgggtt ctctaataca
    11281 tcaaatttta atctcggtga ataaaaaaga tatattaaaa atccaactaa aaataataca
    11341 ccgacgactc ttataattaa ctttttcatc aatcaaccac ctaaaaagta ttaatactat
    11401 tgtaaaaaac aacacattaa ttagcaaatt ttcaacactg acataactgt gtcgtttcga
    11461 taaaacaaaa tcatcttcag gcataatttt aacgtcataa agattttccc tacactctat
    11521 atcataacct atctttatgt tttcaggttg aatttcatta ttaagattaa aatatgtata
    11581 aaaaaatgga cagttaaggt atcaaatgaa taccatcaac tgtccgacta ttcttcatca
    11641 aaaaacctga taaaacaaat tgccttatca gattagtatc atttgtataa gcatattaat
    11701 gaccaaatgt tgctttaatc agtgatgtcg tttctccacc tggatataat acatataata
    11761 ataagtaaac tgctacacct gtaattgcag tacagaacca tataactgaa gcgaatggcc
    11821 cgaatttgcg gtgtacatta tatttatctt taaatgcagt aataatttga actaggccta
    11881 gaataccacc aattgttgct aaattaatgt ggaaaaataa gaaaatcgta taatatttct
    11941 taattgatgc tggtccgcca aatgctgtat taccgataaa aatcgttcta cttgcataga
    12001 ttaagaaaaa agttaaagca aaaacagctg cagctaacat aacatttttg tgtttattta
    12061 tttccctttt ccaaataagt ctccaaccaa tggcaattaa aattgcacta atgacaatac
    12121 atgtcgtact aatcgttggt aaaattggaa cgcccatatt tttcatccta acttaattaa
    12181 tctagatcaa agtaagtaat gaaacaatta cagctaacac gaaaaagatc actaaataat
    12241 ttagtgaata tataaacatt tgtgttgccc attttgtttg atctgaattt ttcttaaatg
    12301 ttgttaaacc taatgcaatc catcctaaat ttaataatgt agctaacact acgaatacga
    12361 cacctaaatt tattagtaat aaaggtactg gcaataaaat aatcaaccag ataaacatac
    12421 tgacacgtgt acgtttaaag cctttaactg atggtaacat tggaatattt gcaagtgcat
    12481 attcatcttt acgtttaata gctaaggcat aaaaatgaat tggttgccaa caaaatacaa
    12541 ctaaaaacag cgcaatcgct gttaaactaa tttgtccttc aattgcaacc catccaatta
    12601 gtggtggtac tgctccagga aaactcccaa tcactgtgtt ccatgttgta tgtcttttag
    12661 accatattga gtaataagac acataaccta caatccccat aagaccaagt acgcctgatg
    12721 gtatattcaa taaaaacaaa caaatttctc caactaacat cataccaaaa cttaatagta
    12781 ataaattttg acctgtaatt ctattattta cagttggtct attttgttta ctaggcataa
    12841 tacgatcaat atcttggtcg taataattat ttaacgcaca tgcgccaccc ataattaaag
    12901 tagatccaaa tagcattaat aaaatttgag gtattgatga taagaaggaa tgatttgtca
    12961 ttacaactgc tagccatgcg cccgcaaaag ccggaattaa gttaccttga acaagtccca
    13021 ttttaattat ctgttgcaat tctttgaagt taactctgct aatattttgt gacaaagtat
    13081 gctctttgct cataatcccc ctccttaaat ttgttcatat aagattatga tatcttagat
    13141 tgcataaaaa gactaggttt aataaaatta aaatgtgaca aattaacgac aagagaaaat
    13201 gtcaattttg tgacacaaat aacatttaat ttattgctat aatgtatatg ttagaaaatt
    13261 ttaataagta gaatcatgca tctaaaagag attaatattt aagcttcaaa tttgagtaaa
    13321 cgtggattac ataattatcc caataaaaaa atcattacga ttaagttctt tttatgtcgt
    13381 ccacatacaa tacttgtaaa attaaatcat atttcctgcg ttggatccca tcttttcata
    13441 tcctacaatc aggtcaattt atagtatcat ctcaaatccg gctattaatt ctaattctca
    13501 gtgatgcgtt tttttatgat ggggtgtata aattgtttgg caaaaagaat ttaaaatggt
    13561 taggtgtcgt agcaacgtta atgatgacat ttgtacaact tggtggagcc ttagttacca
    13621 aaaccggatc agctgatggt tgtggttctt cttggccact atgtcatggt gcgttgattc
    13681 cagaattctt tcctattgat acgattattg agttaagtca tagagccgtt tcagctttgt
    13741 ctttattaat ggtcttatgg ttagttatca ctgcatggaa acatataggc tatattaaag
    13801 aaattaaacc tttatcaatc attagtgttg gattcttatt attgcaagca ttaatcggag
    13861 ctgccgctgt tatttggcaa caaaacgatt acgttttagc attgcacttt ggtatatcat
    13921 taatcagttt ctcatctgta tttttaataa cattgattat tttctctata gatcaaaaat
    13981 atgaagctga cgaattatat atcaaaaagc cattaagacg tttaacatgg ttaatggcaa
    14041 tcatcattta ttgtggtgtt tatactggtg cactagtgag acatgcggat gcaagtttag
    14101 catatggtgg ttggccattg ccattccacg atcttgtacc acattcagaa caagattggg
    14161 ttcaactcac gcatcgtatc atggctttta tagtgtttac gattattatg attacttata
    14221 ttcacgctgt taaaaattat ccaaataatc gtactgttca ttatggttat acagctgcat
    14281 ttatacttgt tatattacaa gttatcacag gtgcattatc tattatgaca aatgttaacc
    14341 tgataatcgc acttttccat gcattattta tcacttattt atttggtatg acaacatact
    14401 ttatcatgct aatgttacga tcagtaagaa gtgacaagca ataacaaaaa agcaaaccgt
    14461 aattttaatg gcacgcccat taaaattacg gttttttata tcaatattta aaattaaacc
    14521 taagccatgt aaaaacgaga ttacacgtca attgttgtgt aatctcgttt tattttaatc
    14581 attttagtca gttgcttttt caatttcgat taataaatcg cctgtcgcta ttgtgtcacc
    14641 attatttaca gttacttgtt taatcacacc gtcaaatggt gcttgaattg ttgtttccat
    14701 tttcatagct tcagtaatta gcaacggctg attagctttc acagtttcac caacactaac
    14761 cttgacttca gttactgaac ctggcatttg agcaccgata tgacttggat tactcttatc
    14821 tgcttttggc ttaacgttcg catttgtatg cacattttca tctttaatgt aaatacgtct
    14881 cgcttgacca ttcatcgcat agtaaatcgt tctattacca ttttcatctg gttcactaat
    14941 cgtttctagt ttaataatta atcgtttacc cttatcgatt tcgatttcta ctgtttcacc
    15001 attacgcatt ccaaagaaga atgtaggcgt atcaagtaac gataagtttc cgtattgatt
    15061 tctagtttga atatattgtt catatacttt tggatataat acataactaa taatatcttg
    15121 ctccgtaaca ggaccttgtt gctcttcttc aagcaactca cggacttttt caaaatcaac
    15181 tggctctaga tattcacctg gacgagctgt tagtgcttct tggcctttta aaataaccgc
    15241 ttgtaaatct ttattaaaac catttacagg ttgtcctatt tcgcctttga agaacgacac
    15301 tactgattct gggaaatcta atttatagcc atctgtaatc acggattgtt catcaagatc
    15361 attttgtacc atataaagtg ccatatcacc aactacttta gacgatggag ttacttttac
    15421 gatatcacca aataagaaat tcactctgcg atacatatct ttgacttcat caaatctttc
    15481 gcctaaacct aaacttttag cttgttgact taaattcgaa tactgtccac caggcatttc
    15541 atgttgataa atttcagtat tcggtgattt gatatcactt tcaaagtctg aataataagt
    15601 acgtacagtt gaccaataat gactaagtga ctccatacct tcaatatcag ttctaaggtg
    15661 gcgtgggaag ccatttaatg cataatataa cgaattggcg cttggctgac ttgttaaacc
    15721 actcattgaa gcaacagcag tatcaatgat atcgacccca gcatctattg cttgtttgta
    15781 tgttaataaa ccattaccac ttgtatcatg agtgtgaaga tgaattggta aatctacagc
    15841 tgattttaac tcaccaatca attcgtaagc ggctttaggt tttaataagc ctgccatatc
    15901 tttaatcgct aaaatatgga aaccttcacg ttctaactct ttagctagtt tgacataata
    15961 ctctaaagta taaatgtttg atcgctcagg atttaaaatg tcacctgtat aacaaatagt
    16021 accttcagag attttgcccg cttcttgtac tgcttcattg gcaactttca tttgatctac
    16081 ccagtttaat gaatcgaaaa ttctaaagac atctatgcct gctttagcac tttcttgtac
    16141 gaatttatga ataacattat caggatagtt tttataacca actgcgtttg aagcacgtaa
    16201 caacatttgg aataatacat ttgggatagc tttacgtaga cgttcaagtc gttcccatgg
    16261 gttttccttc aagaaattat atgccacatc aaatgtagca ccgccccaca tttctagtga
    16321 gaaaccatct ttaaatacgt ccgctgtttt ggatgcgata ttaatcatat ccttagttct
    16381 aactcgtgta gctaataatg attggtgtgc atctctaaag gttgtatctg ttagtaagac
    16441 atcatcctgc tttttaaccc attcagctac accttttgga cctacttcat caagcaattg
    16501 tttcgtacca ctaaatgaag cgattttact tgaagataca gttggaattg atgctaattc
    16561 atagtctggt ttcggacgtt tctcaacatt tgggaaacca ttaattgtta cattacctat
    16621 atattctaat gttttagtac ctctatctag agacggctga atgtcgaaaa gttctggtgt
    16681 ttcttcaata aatttagttg tgtaatcacc acttgtgaac tttttattct tcattacatt
    16741 aattaagaat ggaatattag ttttaacacc acgaatacgc atttctcgta atgaacgtac
    16801 cattttttct tctgcttgtt taaatgatat cgcatgtgta gataatttta cgagtaatga
    16861 atcataataa ggtgatatct cagcaccttg gaaaccatct ccagcatcaa gacgtacacc
    16921 aaagccaccg cttgaacgat aagcaatgat tgttccagta tccggcatga aatcatttaa
    16981 cggatcttct gttgtaatac gacattggat ggcatagcct aatgttgtaa tatctttttg
    17041 ttgcggcata ttaatctctt caccaaataa atcggcacct gctgcaacta aaatttgtgt
    17101 cttaacaata tcaattcctg ttaccatctc tgtaattgta tgctctactt gtacacgagg
    17161 gttaacttct ataaagaaga attcgtcacc agatactaga aattcaacag tacctgcatt
    17221 gacatattta atattttcca tcaattgaat tgcagcatca caaatacgtt gacgtaatgt
    17281 tggtgataat ccaactgatg gtgcaacttc tacaactttt tgatgacgac gttgtactga
    17341 acaatcacgt tcaaataagt gtacgatatt tccatgttcg tcacctatga cttgtacttc
    17401 aatatgcttt ggattatcaa tgtatctttc tatgtaaact tcactattac caaatgattt
    17461 ttcagcttct gattttgctc tatggaaagc atcttctaat tcactttctt cacgaacgat
    17521 tctcatacct ttaccgccgc caccacttgt ggctttaatc attagcggga aaccagcttc
    17581 ttctgcaaat tcttttgcta attcatatga tttaattgga ccgtctgtac caggaataac
    17641 tggtaaatct gccttgatag ccgttgtacg agctttaact ttatctccaa acatatctaa
    17701 atgttctaaa tgaggaccaa taaatttaat tccttcttct gcacaacgac gcgcaaattg
    17761 ttcattttca cttaaaaatc catagccagg atgaatcgca tccacattcg cttgttttgc
    17821 tacatcaatg atacgctcaa tatttaaata actttcagca ggacctaaat cacttccaac
    17881 taaataggat tcatctgctt tatatctatg taatgaactt ttgtcttcat tcgaataaat
    17941 tgcaactgtg ctgatgtcta attctgccgc cgctctgaat atacgaattg caatttctcc
    18001 acggttagca acaagtaact tttttatttg tttcaatagc gatacactcc tcaaactatt
    18061 agaattttct aactaattag ataataaaat tttatcttaa agcgctctgt tttgctatag
    18121 ttatgtttca aattttcaaa atttaacatt cttgagacaa ttaaaacctc cgcttcagaa
    18181 ataataattt caaaaatgac tatgcaacaa caggtagttc acgtttttgt tgtgaaacat
    18241 tttcgatttc tacaactcta aaaaattaaa aataaaattg caaaacatca acatttatta
    18301 tcaatagcga taactttatc ttatcatcat gattctaatt tcgccaccac atttagtaat
    18361 ttttagtcat aaaatttagt tataattata cgttgttttg tttataaaat ttgataatca
    18421 tgagtaatct cgtaatatca aaacaaaaag gaagttaagc gttgtttggt tgcctaactt
    18481 ccgttattga actcatcagt ccaatttgac aaagagtata taaatagcca atgtttagca
    18541 ttgcttaatg acagaagtca tctcgtacta aatattggct agtatttttt taattaaatt
    18601 gtcttcttat atcaactttt tgttgttgtt tctttcgttg ctggtctact ttgatttgtt
    18661 tacctacaat cagaagtaat cccatagcaa tacttaaact aatcattgat gatccaccaa
    18721 agctgataaa tggcaatggc acaccagtta atggaattgt tgccgaaata ccgccaatgt
    18781 ttacaaacgt ttgacttcca aagtatgtgg caatcccaac acacacaagt ttataaaaat
    18841 atgatgatgt tttatttgca aactggaagg cacgatatac aataaagaac tctaaagtaa
    18901 taactagcaa tcctccgatt aaacctaatt cttcgcaaat aattgcaaaa ataaaatctg
    18961 tatgtggttc tggtaaatag cccaatttca ttgcactatt tcctaatcct tttccaaata
    19021 cgccaccgtt acctatcgca agcaatgaat tggaaatatg gtatccagtt cctgattcga
    19081 attggaatgg atctgttagc gtactaaatc tggcagttaa atagcttggt aaccaaccag
    19141 ccattaatgc aatgacaaat actactaaga atcctagcac tgctggtata ccaaatctta
    19201 ggactttgtt taccccaatt cctgaataaa aaataatcgc aactaaaata attaatatta
    19261 gtaatgtttg ccctacgtct ttttgtaaga aaactaaaaa cgtacaacct aatgctaata
    19321 caataggact taaaattaat tttggtttac ttaatactct aggcattttt ttactgatca
    19381 taaatgggat atataatatg attgcaattt ttaataactc agatgcctgt aagttcataa
    19441 atcctaagtt tatccaactt ttagaaccat taatatcttt acctattact aacgtcagta
    19501 ataatagtga gacgatagtt ataatcatac ctttttgcac tttaatatta ctcagtaatt
    19561 taacattcat taaaaatgca ataaaaaata caattataaa actcattatg acatatgcta
    19621 attgtcggtt gtaaaaatac gttcctggaa catcgatacc accagtcaat gtgcctttag
    19681 ttgctgtaac catacttgca ctatatacca tcactaatcc aattaaactc aatacaatat
    19741 atgtaactaa taacggataa tcaataaact ttgaggtttt accaatatac cgtaaaatac
    19801 ttctaaaatt cttcatatat tcagtcatcc aattctacaa tttatacttc aaatgatttc
    19861 gttttatact ttaattttaa aaatccatgt tacttattat atacatgaca cagtcataat
    19921 cacaaatatt aacaggtctc ttgaggtaat ttatagaata tttgtttact taatatcgtg
    19981 aattgctaaa acccaataaa agtgactgac atgtcatcaa gaagacaaca taacagccac
    20041 tttaatcagt aattaaacta taaatataaa atcggcgcag ctcaattgtc gatatctcac
    20101 gccattttaa tatgcttata tattaaacct taaacaagtg taaaagcttc atgtaatttt
    20161 gaaagttctt tctcaagacg taacataatt tgtttgccat cttcgcggtc aactaaacct
    20221 aatttaacag caaaatcaac ttctttttga agtccaaaca tttgtgtatc tagtacttct
    20281 tcatataatg ggcatgaagg taatgttaaa ttatctagtt gaactttaat cagatgcaag
    20341 atttcatcag catctttagt caattgtttc aaagctgcat ttttcattgt tgcttgtttc
    20401 gccatgacac gctccccctc tatataaatt ctcaagtctt actaaaagtt tatcttacta
    20461 aatattaaaa agcaagtaga tttaaaatgt gtcgttagca atttgtgtta aaataatgct
    20521 atatacattg atagggagtg ggaaaatgat acaaattaaa ggagccgtaa agtttcctat
    20581 aacattagat agtacgactt ggattttcga tgatagaaaa gttagcatcg aagatttaga
    20641 aaaaggtgta tttgatggtt caaaaccaat cgactttgaa gataatcatg aatggaatcg
    20701 tgctatccta gaaggacaaa ctaatccgcc tactttaaat tcagaaataa aatataaaaa
    20761 acgtgccatg ttagaaggtt catttgtcat taatatgaca ccatttttca aacattccga
    20821 accacatgac tctgcaacta ctattcgatt atcaaatgag catgatcatt tagatatacc
    20881 gatagatcta ttaccctatt tatttttcca atttgcaaaa gacggtaaac gactttacag
    20941 cgataatggt gtagatagtt ttatttacaa tcaagaagat ggttattcat atcgaatcaa
    21001 ccatgtaact catattgagg tgatttaatt tgagacaagt gcaatgcatt atctgtgatg
    21061 caaaagtatt tatagatgag cgcacaactg agtctaaacg acttaaaaac aatcctattc
    21121 gaacatttat gtgtgatgat tgtaaaagtc gattagacac acctaaacaa cgtgcgcaac
    21181 actatccgct cgattaatat ctgaataaac aagttagaaa tttgaaaatg tgaaagtaac
    21241 aggaaataat agcatttaaa cactttttca aatattatat gccaaaagag aagctaagca
    21301 actttcatcg ctcagcttct cttttattat gttaaattat tcgttttctt gcatcatttg
    21361 tttgatacgc tttgcttctt tttcacgaac atttttgttt aaaattttct ttcttaaacg
    21421 tatactttct ggtgtaacct caacaagttc atcatcatta atgaattgta acgcttcttc
    21481 caatgttaga atacgcggtc tattcattgt ttgtgtttgg tctttcgttg cagaacgtac
    21541 gttagtttga tgttttgttt tagtgatgtt aacagttaaa tcattttcac gattatgttc
    21601 accaacaatc ataccttcat aaacttcagt accaggttcc atgaagttta cacctctatc
    21661 ttcaagtccc aaaatggcat aagtacttgc agaaccttga tccattgaaa ttaatgcacc
    21721 attacgacga ccgccaattt gtgctttaat acgtggtcta aattcttcaa atgtatggtt
    21781 aataataccg taacctcttg tcattgacat aaattcagtc gtataaccaa tcataccacg
    21841 agccggtaca ttaaagatta aacgtgtaag tccattatca gttgtagtca tatcaaccat
    21901 ttcaccttta cgtgcaccta atgattcaat aacagcacct gcattttctt gtggcacttc
    21961 acattgcaca cgttcaaatg gttcacacat tacaccatct atttctttaa taattacttg
    22021 tggttttgaa acttgtaatt cataaccttc acgacgcata ttttcaataa ggattgataa
    22081 atgcaattca ccgcgaccag caactaccca tgtatctgga gaatctgtgt tagaaacttt
    22141 caaagataca tctgtttcta attgttgatt taaacgttct tgaatttgac gtgctgttac
    22201 aaagtcacct tcacggccag caaatggaga attgttaact ttaaatgtca tttcaagagt
    22261 aggctcatca atacgtagaa ctggcaatgc ttcttgatgg tcatgtggtg ttacagtttc
    22321 accaacatta atgtcttcca tacctgaaac agcaattaaa tctccagctt gtgcttcttc
    22381 aatttctaaa cgttttaatc caaagtaacc aaagatttta gttacacgga agtttttcac
    22441 tgtaccgtct aatttaatta gtgatacatt atctccgaca cgcattttac ctctgaatac
    22501 acgaccaata ccaatacgtc caacataatc attgtagtcc aacaatgcta cttggaattg
    22561 taatggctca tcactgttat caattggagc tggtacataa tcaataattg tttcatataa
    22621 tgattgtaaa ttatcatctt gtttttcagg atctaagcta gctgttccat ttactgctga
    22681 agcataaaca acagggaatt ctaattgttc atcgtttgct tctaattcaa taaataaatc
    22741 taaaacttca tctacaacac cctctggacg tgctgatggt ttatcaattt tattaacaac
    22801 aacaacaggt ttcaggtttt gttctagcgc ttttttaagt acaaaacgtg tttgaggcat
    22861 tgtaccttca tacgcatcta ctactaagac aaccccatca accattttca taatacgttc
    22921 tacttctcca ccaaagtctg catgtcctgg tgtatccaaa atattaatac gtgtaccttt
    22981 ataatcaaca gccgtatttt tggctagaat cgtaattcca cgctctcttt cgatatcgtt
    23041 agagtccatt gcacgttcat cgacatgttc attttctctg aatataccag attgttttaa
    23101 caactcatct actaaagttg ttttaccatg gtcaacgtga gcaataattg ctatattgcg
    23161 gacatcttct cttttattag tcatataaat agtttccttc tttcttaagt aaaatcccac
    23221 ttttaattac aactttttta ttatatcata taattgagaa aagataagca aaaggtgggg
    23281 ataggatgaa acaaaaaaaa tctaaaaata tcttttgggt attttctata ttagctgttg
    23341 ttttcttagt attatttagt tttgctgttg gtgcatcaaa tgtaccaatg atgattttaa
    23401 catttatatt actcgttgca acctttggaa ttggatttac tacaaagaaa aaatatcgag
    23461 aaaacgattg gctataagtt atatcgacaa taacacgcgt tgatttaaga ccacacatgt
    23521 tcattatgaa catttaaatg gttttatatt ggcgcgtgtt tttattattt aaggtataaa
    23581 agcgtaatat gttacctaat tgttaggact acatattacg cttttggtaa ttattttgat
    23641 tttcttttaa atcgttgttc atgtaattgt attaacgtat catggtaggg ctctaaataa
    23701 tcattgctaa tttcttgatg gagacctcga tttccaacta agattgaatt tggaccacta
    23761 attgttaatg gttctcctag taaatttgaa gcttgtccat ttacttcata taaaataacc
    23821 aatccgccag caaaatccca tggttgaagt cttggcgtca tatatgcttc taaattacct
    23881 gtagcaactg aaacgatttc aagcgctgca ctaccatatg cccttgcact tctagaatca
    23941 ttaacaattt ctttaaagat ttctcctaaa attggtttag ttaaccagtt cggattgatc
    24001 ccaataatgc tttgtcttag attagaatca ttcaatggtt tcaagggttg gctacctcga
    24061 tatgcgcctt cccctacttt agcatgatat aagacgtcag ccataacatc atatacaaaa
    24121 cctgcataag gtttaccatc gatataaata ccaattgaaa ttgcgaaatt ttcttgttga
    24181 tgaacaaaat tcaatgtacc gtctattggg tcaacaaccc ataccgtacc tttggaagta
    24241 tcgatgtcat gaccatgccc ttcttcacct aatacttgat gattgggata tgtttctaaa
    24301 attgtatcaa aaatgaaatc ttctgttgct ttatctacat ttgtaacaag gtcattcgga
    24361 tttgactttg tttcaattgt taaattttgc tccatcaatt gtttaattct aattcctgct
    24421 tcttgaataa gtccttgggc aaatccataa agtgccataa catcatctcc taacatcttt
    24481 attatacatc aacattttat aaaaataact tcttatgata aaaatgaaaa tactaatttt
    24541 aatgagagcg tcttaagccg caattgataa aacatatgct acaatatttt taaacactat
    24601 acaggaggta ctctatgaca aaatatacat ttaaacctaa agatttcaaa gcgttcaacg
    24661 tagaaggctt agacgcacga atggaagctt taaacgaata catacgacca caactccatg
    24721 aattaggaga atattttagt gacttcttta caagtcaaac tggtgaaaca ttttatcctc
    24781 acgtagcaaa acatgctaga agaagtgtga atcctcctaa agatacatgg gttgcttttg
    24841 ctacaagcaa aagaggctat aaaatgttac ctcatttcca aattggtatg tttgaagatc
    24901 aactgtttgt tatgtttgga atcatgcatg aagcaaaaga taaagcaaca cgtgcaaaag
    24961 tttttgaaag aaaatttaaa gctattcaac aattacctga tgattatcgt gtttgcttag
    25021 atcatatgaa acctgataaa ccatttatta aagatttaac ggatgatgat ttaaaagaag
    25081 cgatacaaag agccatcaat gtgaaaaaag gtgaattctt tatagcgcgt gcaatcacac
    25141 cacaagataa aagattaaaa agtgacaaag catttattgc atttttagaa gaaaccttcg
    25201 atcagttctt accattttat tctgcataaa taactttgtt taaataatag agcacgtaat
    25261 cacatccatg atttcgtgct cttttttctt aatattaaat cgaacgttca acataataat
    25321 tcatactttt aaaaaataaa ataaatttag gttgacctaa acattttatt aggttattat
    25381 attgtccata agaagtagag gtgagtcaaa atgaataata aacgacattc aacaaatgaa
    25441 caattaagtt tagacgaaat aaacaataca attaaattcg atcatcgcag ttcaaataaa
    25501 cagaaatttt tatcatttct tggacctggg ttattagtcg ctgttggtta catggatccc
    25561 ggaaactgga taacatcaat gcaaggtggc gcccaatatg gctatacttt gctattcgta
    25621 attcttattt caagtttatc agcaatgtta cttcaaagca tgacagtgag attaggaata
    25681 gcaacaggta tggacttagc tcaaatgaca cgacattatt tatcaagacc tattgctata
    25741 atcttttgga tcattgcaga actagcaatt atcgctacag atattgctga ggttattggt
    25801 agtgctattg ctcttaatct cctatttaac atacctttaa tcgtcggtgc actaataact
    25861 gtacttgatg tatttttact actatttata atgaaatatg gttttagaaa aattgaagct
    25921 attgttggta cattaatttt cacagtgtta ttcatcttta tatttgaagt ctatatttca
    25981 tcaccacagt tgaatgctgt gttaaatgga tttataccac atagtgaaat cattacaaat
    26041 aacggcattc tctatattgc attaggtatt attggcgcta caattatgcc tcataatttg
    26101 tacttacatt catcaattgt acaatctaga acatactcaa gacataacaa tgaagaaaag
    26161 gcgcaagcga ttaaatttgc tacgatagat tcgaacattc agttatcaat cgcatttgta
    26221 gtcaattgct tattattagt gttaggagca tcactatttt tcaactcgaa cgctgacgat
    26281 ttaggtggtt tctatgattt atatcacgcc ttaaaaactg aacctgtact aggtgcaaca
    26341 atgggtgcaa tcatgagtac attatttgca gttgcattat tagcgtcagg tcaaaattca
    26401 acgattactg gtactttagc aggacaaatt gtaatggaag gatttttaag attacacata
    26461 ccaaattggt taagacgttt aattacacgt tcccttgctg tcattcctgt tatcgtatgc
    26521 ttaatcattt ttaaaggtaa tgcagctaaa attgagcaac tacttgtatt ctctcaagta
    26581 tttttaagta ttgctctgcc attctgttta ataccattac aattagctac tagtaataaa
    26641 gacttgatgg gacctttcta taataaaaca tgggttaata tcatttcatg gacacttatt
    26701 attattctaa gtattttaaa tgtctattta atcgttcaaa cattccaaga actacaaagt
    26761 taaaaataaa accattaaaa tgttggttgt atctaataat taacaactta acattttaat
    26821 ggtttttttg ctatgaacat attaatgata aatatactca tcgtccttat gtgtagtttc
    26881 ttttgattct tttttagaaa tcaacataat catcacgata acccataaga caattgcaat
    26941 taaattaaga gccatcaaac ttacaattat cgcgataaca aaaagtataa tcgataattt
    27001 tctacgccct ttaatacaaa ttgtcgcaaa tataccataa agtgttgaaa ttaataaaat
    27061 aattgctaat gcacccattg ttgtctgaag catatctaaa gaaacattgc caccgttctg
    27121 agataattgc ttcgctaatt cttcacgttg tgatgcatta ccacttttta aagaaaaata
    27181 ggatagcccc ataactaata aataaataat actaatacta tttgcaatcc aagccatgat
    27241 taattcaggt tttctattca tcttaaaatc ctttctttgt ttaatatttt aataagtata
    27301 ctacgagcct atagatatac gcacattaaa ttacttgtat attaacatat ttttcatcta
    27361 atttttataa taaacatctg aattcagatt gatgataatt taggtgtatg gtaatgagaa
    27421 atcgtcattt aaaattttga cacctaaaca ctttaattaa acgttatcga tgattaacct
    27481 catataaaaa cccagattaa taagcaaaag acctctactt actaatctgg gtatcatcaa
    27541 tatttattct tgctcttttt tgtccttaac ttcacttgaa ttgcgttctt cagaaatatc
    27601 attgttgtaa atttgacgtc gctcttcaaa attcattcga cgttgactaa ctgcgctagg
    27661 ttgatttttc ctacgttctt tcattcgttg gttataagct ttacgttttt cttttttctt
    27721 agctttaatt tcagcttttt ctcgcttttg ttgtgctttc aattcttttg gatcaacttc
    27781 aggttctgca taataaccat catcttcaat acctagttct tcagtacttt tttgtttgta
    27841 tttagcctgt ctggataata ctgatggttc ttcctcagtg cgctcatcat gattatattc
    27901 actttcaact gcacgtttag gaaattgatc atatttatct ctttcctgtt cttgatcata
    27961 tacagtattt gatttatcca attctttttc atatttaggc acatcataat aatcatcttt
    28021 cggttggggg cgctcataca caggttcacg ataatcataa atcggtccgt tatactcttc
    28081 ataatattgt ggcgcaacca tttcaacttt atcttttctt ataaatagca tcatcgcaat
    28141 aataaagaat aatatcggaa tgattaaagt aacgataagt aaaactaaag gaatcgttac
    28201 aattgctgat attaagaata agaaacctga caagattctt atattcatag atatgagagc
    28261 taaaaatgaa atcaacaaac aaacaataaa gtaaacgata atagcccata taccattttg
    28321 taaccatatt acaaattgtg ttgtattata gccatttcca gctaataatt gctggataaa
    28381 tgcattattg tttaatgtat tttcaagatt agctatcgat gtgttattac tgaatgaaac
    28441 aagtgctata aacatcgtaa tgacagtaag cactaataac atcacccaac ataaccaacc
    28501 tagaactttt tcagttaatc tacttactgg acgtttaatt tgagtaaatt gttctccagt
    28561 cattcgttac aactccttat agtacttatc ccgttattat aactaaatat atagtaaata
    28621 actactattt atgattttat tttaatgaca ttttgaaatt caaaaagttt tcattgtatt
    28681 cacttaaaac ttcaggtcct aaatctttat aaacttcaag gcgttcttgc tctttcttag
    28741 tcggataaaa acgatggtcg tctttaatct ctttaggcaa caattgtcga gcagccttgt
    28801 ttggcgttgc atagcctacg aattctgtat tttgcttgtt atttttagca tctaataaaa
    28861 aattcataaa tttatatgca ccctctttat tttgtgccgt ttttggaatt accatattgt
    28921 cgaaccataa attcgatcct tctttaggaa taacataatt atatttatcc ccttcttgca
    28981 ctagaggtgc tgcaacacca ctccaaacaa ccgctatgtt accttcattt tgttgaagca
    29041 tcatggtaat ttcatcacct acgacacctc ttacttgtgg tgctagtttg gttaaatctc
    29101 gctctgcttc ttttaaatgg tgcgaattac ggtcattaag attataccca agtttattca
    29161 aactcatgcc tataatctct ctagcaccgt caactagtaa aatttggttt ttaaatttag
    29221 gattatacaa tgacttccaa ctatcaaatg attcatttgg atacttttct ttattatata
    29281 aaatacctac agttccaaag aaataaggta aagaatattt attgccttta tcaaatgaca
    29341 tattcatata atctgaatct aaatttttaa tattaggtac cttattatga tctattggta
    29401 acaataaatg atctcttttc aatttttgaa ctgtatattc actaggaaaa gcaacatcat
    29461 aatgtgtacc gccattgcga attttggctt ccatcgcttc atttgaatcg aaagtttcat
    29521 aaacgacttg aatgccagtt tctttttcaa atttcttaat taactctgga tcaatatatt
    29581 cgccccaatt gtatacgtaa attttttgat ttgtatgcac ttgttcttta gatttaaacc
    29641 aatgacttaa agtaagacaa agcataccca caactaatgc acctataatg agttgtaaaa
    29701 aacgtttcat tattttacac ctcgcttgat tagttttttc ttatttatca cgtattgaat
    29761 caaataatat cctagtattc ctaatacaat aacagcaaac aataatgttg aaatcgcatt
    29821 aatttccata ctaattcctt ttctcgccat agcataaact tcaactgata acacactaaa
    29881 gccattacca gtaacgaaga aacttactgt gaaatcgtct agtgaataag ttaaagccat
    29941 aaagaaacct cctataatag aaggtaaaat attaggaata ataatgttgc ttaataattg
    30001 tggttcagtc gctcctaaat ctcttgcagc atttaacata ttattattca tttcatacag
    30061 ttgtggtaag acgataatca caactatagg tatgcaaaat gcaatatgag atattagaac
    30121 tgtccaaaat cctaaaccaa gaccagtaaa atggccaatc gttgtaaaca taattaagaa
    30181 tgatgcacct atgacaacgt cggatgatac catcaagaca ttattcaatg ttagtaaagt
    30241 tactttaaac tttttatttc ttaaataata aatagcaatg gcaccaaatg taccaataac
    30301 tgtagaaatt gaggctgcta aaagtgctac agctatcgta ttaaaaatga ccgacattaa
    30361 atgatcattt tgaaataatg attgataatg ctctaatgta aaatgttcaa agtgaatcat
    30421 attaccagcc gaattgaatg aatagaacat taaaaagaat attgggatgt ataaaatcgc
    30481 taaaagtatc ccgatataca gctttccata ccatttcata tgattcaccc tctcccatta
    30541 gatgattttg taatgattaa aatgaatgcc ataaatacaa ttaagaatat agctatagtt
    30601 gatcccatac cataattttg aattgttaaa aattgttcct ctattgccgt acctatattt
    30661 atgactttat tacctgcaat taatcttgta atcataaata atgaaagtga tggaataaag
    30721 gttacttgaa tcccagtcat aacaccttct tttgttaacg gcatgattac ttttctaaaa
    30781 gtatagaaag gactggcacc taaatcactt gaggcctgca ataaattatt aggaattgct
    30841 ttcatgctat taaatatagg taaaatcata aatggtatat aaatgtaact tgccactact
    30901 aaaaacgcac cagttgtaaa taacaaattg aatgatggta aattaaataa gtggaaaaat
    30961 tgattaatca cgccatcatg acttaataaa cctataaaag catatgtctt taacaataaa
    31021 tttatccatg ttggaataat cattatcatt aataagatat tttgaaattt cgaatgagta
    31081 atataatagg cagctggata actgatagcc aacgtaataa ttgttattaa agcggcatat
    31141 aaaattgaat atgcaaacat tttcaaatat tttgtagtaa aaatttgttg ataattcgtg
    31201 aaactaaaat gtccattgat atctaaaaat gaaaaataaa tgagtaatac aactggtaca
    31261 ataataaata taaccatcca tagtaaatac gggattaaga gaaatttatt agtattacgc
    31321 attgtctact tcctcatagc tttcaatacg tttatcaaat tcttcttctg tttctccagg
    31381 aaccataata tgaatggctt caggatcaaa ataaagacca acttcactgc ctacttcagc
    31441 ttttttagtc gtttgtatta cccattcata acctttattg tctatacaac atatttcata
    31501 gtggacccct ctaaataaca tagaatcaac agttgcttta aataatcctt cttcagcttt
    31561 gattaatgat atatcttctg gtcgaataac gacttctact tttttatttt caggaatacc
    31621 catatcgaca cattcgaaat cttgcccata aatattcacg acataatctc taaccatgcg
    31681 tccttcaaca atattagatt ctccaataaa atcagctaca aatcgattca ctggttcgtc
    31741 atatatatct gttggtgtgc caaattgttg aattttccca tcttttaata caaaaagaaa
    31801 gtcacttaat gctaacgctt cttcttgatc atgtgttaca aatataaatg taatacctaa
    31861 tctagattgc aattctcgta attcatattg catttcagta cgcaatttca aatctaatgc
    31921 ggataaagat tcatctaaca ataatatttc tggttcattt acgatagcac gtgcaattgc
    31981 aacacgttgc ttttgtccgc cactcatttc attaatattt cttttttcat aacctgaaag
    32041 ttttactaat tttaatgcct cagttacttt ttgatcaatt tcggtttttg ataatttttt
    32101 taatttcaaa ccaaaagcga tattatcata tacgtttaag tgtggaaata atgcataatc
    32161 ttgaaagact gtattcactt tacgtttatt tggtggtaaa ttaccaattg gtttgttttg
    32221 ataaatcact tcaccactgt caggatattc aaaccctgca attaatttta aaattgttgt
    32281 tttaccacaa cctgaaggac ctaataatgt ataaaagtat cctgattcaa tatcaatatc
    32341 tatgtcatct aagatattaa gatcatcata gcttttacta actgatttta atgataataa
    32401 cggttccaaa taagatcccc cctataaata tgaagctgtc gctacaataa gtattcgtgt
    32461 ttcattgttt gattcgtttg acaaacgatg attatctcgt gctttaaaat acaaaacgtc
    32521 ttcttcttgt gcttgatata tctctttgcc taaattaagt gttatctgac ctgacataca
    32581 ataaataaac gtatcagact ctgatggatt aaaattttta tatgatgctc caggctttaa
    32641 agttaatatt aatggctcca tatcatattc atttgacttt gaaactaacc aatttaatat
    32701 ataaccttca tcatactcat cataaataac ttgttcttcc ttcttgtata atactttttc
    32761 attttcactg tctttaaaaa attcacttgg cgtcgttcct aacacctcta taatatttaa
    32821 gaaagtttcc atacttggtg aggcatgttc actttctatt tgtgaaatgt agcctttcga
    32881 taagtctgta cgttcagcaa gttcttcttg cgttaaattt ttaattcttc taagattttt
    32941 aattttatta cctatgttca tttatttttc cacctaaaaa agctatatta agtttacttt
    33001 tatcaaacat tttgtttaac acttgataaa ggtatcaaaa tatagcttta ttagcaatag
    33061 ttttaaagaa aaaatcctat taaattgtgt taatttcgaa cgaattattt tttagctgtt
    33121 actctttgtt cttcagagtg agtttttaca tcttgaactg ctttgtaact attatagcca
    33181 ctactttttt cgaaagtatt aaaaatttgt ttttcctctg ctttagcagg cacaatttct
    33241 ttaaatcttt tatatgcacc cataaagtcg cctgccgtca cgccggattc ataatacttc
    33301 tctacatgat taaagaaatt tatcactgaa atcatctctt cattactcca gtctaaatca
    33361 attggatact catattccat tgttgaaccc tccatttcaa ttcttttgtt agcatcgcta
    33421 gtataacatg catgtcacat gttaacgata tctcaaatca atttccttac attactttac
    33481 ctaaaacaaa aaagccgtag catatgctac agcttttaat gactgaatct ttatagataa
    33541 tcagttatta cattgtatgg attgggtatc cgatagcttt ttctgctgct tccatagtca
    33601 tctcacctaa tgttggatgt gcatggattg ttaatgcgat atcttcagca ttcataccag
    33661 cttcaattgc taaacctaat tcagagataa tatctgatgc accagtacca actacttgag
    33721 caccgattaa agtatcatct tctttaagtg taataagttt aacaaatccg ttagtatcat
    33781 ctaatgataa tgcacgacca tttgctgcat atgggaattt agaagcttta attgctaaac
    33841 cttcttcttt agcttgcgct tctgaataac caactgtagc taattctggt tcagtaaagc
    33901 atactgctgg cataccaatg taatcaactt cagcagcttg accatcaatt gcttcagcag
    33961 caactttagc ttcatagcta gctttgtgag caagtggtaa acctggaacg atatcaccaa
    34021 ttgcatagat attgctgata gacgtacggc tttgtttatc aacttctaat aatccacggt
    34081 cagcgaattt aacacctaat tcttctaggc ctaattcgtc tgtgtttgga cgacgaccta
    34141 cagttactaa tacataatca gcttcgattg ttttctcttc gcctttagct tcataagtaa
    34201 ctttaactcc gttatctgtt tcttcagctg atttagccat agcttcagta acgatttcaa
    34261 cacctttttc tttcatacct tttttaacag gttgtgtcat ttgtttttcg aagccaccta
    34321 agatatcttt agcaccttca aggatggtta cttctgaacc aaagttagca aatgctgtac
    34381 ctaattctga tccaatgtat cctccaccaa ctacaactaa tttacctggt acttcttgta
    34441 agtttaaagc acctgttgag tcgataacac gtttaccgaa tttgaaatta ggaatttcaa
    34501 ttggtcttga acctgttgca atgattgcat ttttaaagtt gtatgtttgt gcgctctttt
    34561 cgtccataac acgtaagcta ttgttatcta cgaaatatgc ttcaccttta acgatgttaa
    34621 ctttgttacc tttaagtaag ccttcaacac caccagttaa tttattaaca actgatgatt
    34681 tgaattcttg aactttttgg aagtttaaag aaacactttc agcaataaca cctaagtttt
    34741 cagaatgttg tgcttcaaca aaacggtgag aagcatgtag taatgctttt gaaggaatac
    34801 atcctacgtt taagcaaaca ccaccaagat tacctttctc aacgattgtt actttttgtc
    34861 ctaattgagc tgcacgaatt gctgcaacgt atccaccagg acctgctccg attactatag
    34921 tatctgtttc aattgggaaa tctccaacta ccatgtttta cccctccatt aataataatt
    34981 ctggattatt taataaacgt ttaatgtgat tcattgcatt ttggccagtt gcaccatcaa
    35041 tttgtctgtg gtcaaagctt aatgataatg ctaatactgg tgctgcaaca atttctccat
    35101 ctttaacgat aggtttttga gcaatacggc caattcctaa gattgctact tctgggtgat
    35161 tgataactgg agtgaaccat tgtccaccag ctgaaccgat attactgatt gtgcatgttg
    35221 cacctttcat ttcatcggct gttaatttac catcacgtgc tttaacagct aattcattaa
    35281 tttcatctga aatttggaaa atagacttac gatcagcatg tttcactaca ggtactaata
    35341 aacctctatc agtgtccgcc gcaataccga tattccaata atgtttatgc acaatttcac
    35401 cagcttcttc attgaatgaa gtgttaagtg ctgggtattt tttcaatgca gaaacaagtg
    35461 ctttaacaac ataaggtaag aatgttaact tagtaccttg ttcagctgcg atttctttaa
    35521 atttcttacg gtgatcccat aatgcttgaa catcaatttc atccattaat gttacatgag
    35581 gtgcagtatg cttagagtta accattgctt tcgcaattgc tctacgcata gcagggattt
    35641 tttcagttgt ttctgggaag tcgccttcta atgatactgc tgcaggtgct gcaggagttt
    35701 cagcaacttc ttcacttgta gctgaagcag ctgattcatt tgaagctgtt ggtgcaccac
    35761 catttaagta tgcatctaca tcttcttttg taatacgacc atttttacca gatccagaaa
    35821 ctgctttaat gttaacacct ttttcacgtg cgtatttacg tactgaaggc attgctttaa
    35881 cagttctgtt ttcatctact tcttcagttt gagtagctac aggtgcttgc tctgctggcg
    35941 cttcctcttt cgcaggttct tctttagatg atgaatcatc atcatgacct ttaaattgca
    36001 tatcttctgc atcaggtgca tcgattttaa caataacgtc accaactaca gctactgtac
    36061 cttcttctac cataacttct tctacagtac cagatactgg tgatgggatt tctactactg
    36121 atttatcgtt ttgtacctca gctaaaacat cgtcttcttc aatagtatct ccagctttaa
    36181 caaaccattt tacaatttca ccttcgtgga taccttcccc gatatcgggt aatctaaatt
    36241 caaatgccac gtttttgccc tcctaagatt tcgtaaatta aacatttcat tttaatcaat
    36301 gagactaaaa tacgctaact tcgttaactt ttaaaatgta ttaaaattct aaagtttctt
    36361 ttgctttttc gatgatgtca tttttgtttg gtaaccaaac attttcagct tgagtgaatg
    36421 gataaattgt atctgctgct gcaactcttc caataggtgc ttctaatgaa aggattgcac
    36481 gttcacttaa ttcagctaca actgctgcac caacaccagc ttgacgttgt gcttcttgaa
    36541 ctacaactgc acgaccagtt ttttcaactg aagctacaat tgtgtcaaca tcgattggtt
    36601 gaacagtacg taagtcaatt acttcaacag aataaccatc tttttcaagt gcttctgcag
    36661 ctttcattga ttcttgaacc attgcaccgt atgtgatgat tgaaatgtca ttaccttctt
    36721 ttttcacatt agccttacca atgtcaattg tatattcttc ttcaggtact tcttcacgga
    36781 atgaacgata caatttcata tgctctaagt atacgactgg gtcattactt ctaatagaag
    36841 aaattaataa acctttcgca tcgtatgggc ctgaaggaat aacaaccttt agacctggag
    36901 attgagctaa aataccttct aagttatctg cgtgtaattc tggtgtgtgt acgccaccac
    36961 caaatgggct acgaattgtt acaggtgcag ttttagtacc gcctgaacgg aaacgagtac
    37021 gtgcaatttg tccagcaatc gcatcaaata cttcgaatac gaaacctaag aattgtactt
    37081 ccataaccgg acggaatcct tcaactgcaa gacccatcgc taaaccacca atacctgatt
    37141 cagctaaagg tgtatcgaat actctatctt caccaaattc tttttgtagt ccttcagtaa
    37201 cacggaaaac accgccgtta acaccaacgt cttcaccaaa aattaaaaca tcttggtcat
    37261 ttttaagttc agttttaagc gcatcattaa tcgcttgaac cattgtcatt tgtgccatgg
    37321 cttacttcga ctccttctct ttgtaaattt catattgttc tgctaagttt tgaggcatat
    37381 cttcatacat aatttccatt agagaagtaa cagtttgttt ttcagtgtta tcagcctctt
    37441 taattgctgc tttaatatca gcttttgcac gttcaataac ttcattttct ttgtcttcat
    37501 tccataaacc tttgttttca aggaatttac ggaaacgtac taatgggtct tttttctccc
    37561 attcagcatc ttcgtctgaa gttctgtaac gagttggatc gtcaccagcc attgtatgag
    37621 gaccataacg atatgtcata gtttcaatta atgttggacc ttcacctgca actgcgcggt
    37681 cacgtgcttc tttagttgct tgatatacag ctaacgcatc cataccatca acttggatac
    37741 caggaatacc tacagcaatt gctttttgag ctaatgtttc agcagcagtt tgcttgcttc
    37801 ttggtgttga aattgcatag ttattgtttt gaataacgaa aattgcaggt gctttataag
    37861 ctgctgcaaa gttaatacct tcgtagaaat caccttgtga agaaccaccg tcaccagtgt
    37921 aagtgattgc aactgcattt ttaccacgtt ttttaagtgc aaatgcaaca ccagcagctt
    37981 gaatgtattg tgcaccgata ataatttgtg ggctcaatgc attaacgcct tcagggaatt
    38041 gatttccttt gaagtgacct cttgagaata agaaagcttc agttaatggt aaaccatgcc
    38101 aaataatttg aggaacatct ctgtatcccg gtaaaatgta atcttctttt tctaaagcgt
    38161 attgtgacgc taattgtgat gcttcttgac cagcagttgg tgcatagaaa cctaaacgtc
    38221 cttgtctgtt taatgagata gaacgttgat caaggatacg agtccatacc attctttcca
    38281 ttaattctac taattgttca tccgtaagat caggtactaa gtcttcattt acgacgttac
    38341 cattctcatc caaaatttga accatttcaa atttcgattg agtatcattt aaaactttta
    38401 ctgcatcgaa ttgggcttgt aacttaggag ccattcaatt caccatacct ttcccataat
    38461 tgtatagaaa ttcattttat ccttactaat tgtaccacaa ataaatggga ctgttaaacc
    38521 atttgaaaaa gttctgtttt aataaaaaaa gatacagata ataggaactg tattagttgt
    38581 ttcctaccat ctgtattata ttaattattt aaattgatca acgtcttgct tttctttacc
    38641 aaccttattt agtactttcg tatacttatc tgatacttct tttaactttt tatagttctg
    38701 ttctattgct tttgattttt cgttaacacc ttgttgtgtc gcgtcatttt gatttaaata
    38761 tttaaataat gttttctctg agtttacagc ctttttatat gctttcgcgt attcaccatg
    38821 caatttgtat ttttctttta atacatcatc taattgtttt acttctttac gtttaacatc
    38881 attatcaatg ttatcaacgt gactttttgc tttcttaaag tcttgttcag acttcttaat
    38941 tgcgtcttct tctttttcaa attcctttag acgatcatcg gcatttttaa ttaaatcttt
    39001 tactgcttta ccgcgaactg ctgtatcttt actattgaca tcttcagtta attttttctt
    39061 tttctcatct aattcagcaa ttttcttacc aacagtttta attggttctt catcgtcttt
    39121 aattttatcc acttgcttta aatatgcctt aatttctttt ttatccgtag tacatcctgc
    39181 aagcaagaca ctagatgcta atactactgc gattgttttt ccaaatttca ttacttgtac
    39241 ctccacttgc tatttaaatt aaatgataaa taaaatctgc ttggaaatca attttaaaca
    39301 attacattac acatcttcat tactaagtat atctgttgac agttacgtca tttataatat
    39361 aatttttaaa gtcaagatga taaataaatt tctaaagtat cattgcttgg aaccaacact
    39421 ttaatcattt tttaagcaat tagcatatct gaaaatttac atatactatc taaaataaac
    39481 attggcagta gttggttaac tttgtagata tttacacata aaaatgtatg agtatcttaa
    39541 caaccttttt actgtcattc aactaaaaca aattaaaata aggaaggtgc aatatatgtt
    39601 aacaatgaaa gacatcatta gagatggtca tccaactttg cgtcaaaaag cagctgagtt
    39661 agaattacca ttaactaaag aagaaaaaga aacattaatc gccatgagag agtttttagt
    39721 aaatagtcaa gatgaggaaa tcgcgaaacg atatggttta cgttcaggcg ttggtttggc
    39781 tgcacctcaa attaatattt ctaaacgtat gattgctgtt ttaataccag atgatggcag
    39841 tggcaaatct tatgactata tgcttgtgaa cccaaaaatt gtaagtcata gcgttcaaga
    39901 agcttattta ccaactggtg aaggttgcct tagtgtcgat gataatgttg ctggtctagt
    39961 tcaccgtcat aatagaatta caattaaagc caaagacatc gaaggtaatg atatacaatt
    40021 acgactaaaa ggatatccag caattgtttt ccaacatgaa attgaccatt taaatggtgt
    40081 aatgttctat gatcacattg acaaaaatca cccattacaa ccacatacag atgctgtaga
    40141 agtttaaagc acatttttac taattatcaa agcttaggat aaatatgatg tcctaagctt
    40201 tttcttgtac aactttttcg aataaacaac agttaaatat attcaccttt ctaccaaact
    40261 ttttatcccc tcatttaaat tttaccgttt catataaaat cctttaattc tttcttaaca
    40321 ttaatttata atctctacat ttattttaat aaatagaact gcacatttat tcgaaatact
    40381 tagatttcta gtgagataaa ctgctttatt tattatcatt catcatgtaa aataagattt
    40441 aactgaaatt ttagtgttat ttcactaatt ttttaaaatg aacgacatga tgaacctagt
    40501 tattaaccaa atcgttatta agttaaatta tagagatgat tggaatgaat ttatcgatat
    40561 atactccaat acgattttac tagggttaac aataaattaa acaaacattc ttaggaggaa
    40621 tttttaacat ggcagtattt aaagtttttt atcaacataa cagagacgag gtaattgtgc
    40681 gtgaaaatac acaatcactt tatgttgaag ctcaaacaga agaacaagta cgtcgttact
    40741 tgaaagatcg taattttaat atcgaattta tcactaaatt agagggcgca catttagatt
    40801 acgaaaaaga aaactcagaa cactttaatg tggagattgc taaataatga aacaattaca
    40861 tccaaatgaa gtaggtgtat atgcacttgg aggtctaggt gaaatcggta aaaatactta
    40921 tgcagttgag tataaagacg aaattgtcat tatcgatgca ggtatcaaat tccctgatga
    40981 taacttatta gggattgatt atgttatacc tgactacaca tatctagttc aaaaccaaga
    41041 taaaattgtt ggcctattta taacacatgg tcacgaagac catataggcg gtgtgccctt
    41101 cctattaaaa caacttaata tacctattta tggtggtcct ttagcattag gtttaatccg
    41161 taataaactt gaagaacatc atttattacg tactgctaaa ctaaatgaaa tcaatgagga
    41221 cagtgtgatt aaatctaagc actttacgat ttctttctac ttaactacgc atagtattcc
    41281 tgaaacttat ggcgtcatcg tagatacacc tgaaggaaaa gtagttcata ccggtgactt
    41341 taaatttgat tttacacctg taggcaaacc agcaaacatt gctaaaatgg ctcaattagg
    41401 cgaagaaggc gttctatgtt tactttcaga ctcaacaaat tcacttgtgc ctgattttac
    41461 tttaagcgaa cgtgaagttg gtcaaaacgt agataagatc ttccgtaatt gtaaaggtcg
    41521 tattatattt gctaccttcg cttctaatat ttaccgagtt caacaagcag ttgaagctgc
    41581 tatcaaaaat aaccgtaaaa ttgttacgtt cggtcgttcg atggaaaaca atattaaaat
    41641 cggtatggaa cttggttata ttaaagcacc acctgaaaca tttattgaac ctaataaaat
    41701 taataccgta ccgaagcatg agttattgat actatgtact ggttcacaag gtgaaccaat
    41761 ggcagcatta tctagaattg ctaatggtac tcataagcaa attaaaatta tacctgaaga
    41821 taccgttgta tttagttcat cacctatccc aggtaataca aaaagtatta acagaactat
    41881 taattccttg tataaagctg gtgcagatgt tatccatagc aagatttcta acatccatac
    41941 ttcagggcat ggttctcaag gtgatcaaca attaatgctt cgattaatca agccgaaata
    42001 tttcttacct attcatggtg aataccgtat gttaaaagca catggtgaga ctggtgttga
    42061 atgcggcgtt gaagaagata atgtcttcat ctttgatatt ggagatgtct tagctttaac
    42121 acacgattca gcacgtaaag ctggtcgcat tccatctggt aatgtacttg ttgatggtag
    42181 tggtatcggt gatatcggta atgttgtaat aagagaccgt aagctattat ctgaagaagg
    42241 tttagttatc gttgttgtta gtattgattt taatacaaat aaattacttt ctggtccaga
    42301 cattatttct cgaggatttg tatatatgag ggaatcaggt caattaattt atgatgcaca
    42361 acgcaaaatc aaaactgatg ttattagtaa gttaaatcaa aataaagata ttcaatggca
    42421 tcagattaaa tcttctatca ttgaaacatt acaaccttat ttatttgaaa aaacagctag
    42481 aaaaccaatg attttaccag tcattatgaa ggtaaacgaa caaaaagaat caaacaataa
    42541 ataatcaaaa agctactaac tttgaagtga agttttaatt aaactcacca cccattgtta
    42601 gtagcttttt ctttatatat gatgagcttg agacataaat caatgttcaa tgctctacaa
    42661 agttatattg gcagtagttg actgaacgaa aatgcgcttg taacaagctt ttttcaattc
    42721 tagtcaacct tgccggggtg ggacgacgaa ataaattttg agaaaatatc atttctgtcc
    42781 cactcccgat tatctcgtcg caatattttt ttcaaagcga tttaaatcat tatcatgtcc
    42841 aatcatgatt aaaatatcac ctatttctaa attaatattt ggatttggtg aaatgatgaa
    42901 ctctttgcct cgtttaattg caataatgtt aattccatat tgtgctctta tatctaaatc
    42961 aatgatagac tgccccgcca tcttttcagt tgctttcaat tctacaatag aatgctcgtc
    43021 tgccaactca agataatcaa gtacacttgc actcgcaaca ttatgcgcaa tacgtctacc
    43081 catatcacgc tcagggtgca caaccgtatc tgctccaatt ttatttaaaa tctttgcatg
    43141 ataatcattt tgtgctttag cagttacttt ttttacacct aactctttta aaattaaagt
    43201 cgtcaacgta cttgattgaa tattttcacc aattgccaca atgacatgat caaagttacg
    43261 gatacctaaa cttttcataa ctgcttcatc tgttgtgtct gcaacaaccg catgagtagc
    43321 gatatcacta tattcattca ctctattttc atcatggtcg atggccatta catccatgtc
    43381 taatgcattc aactcacgaa cgatactacc tccaaaacga cctagaccga tgactacata
    43441 ttctttaccc atactcgccc tccattaaat gattttcatc aattcattga aaatataaat
    43501 ttaaaattat tataaatgag taccccaact aaattatcta aatgcagtaa tgcaagtaaa
    43561 tgaaagttgg ggtatcgtct caacttatga tttctttcct tcaacatatt ctttgtcgaa
    43621 aacaaataat cttaataata atattaacga tggaagtaat aaaagtaaac ctaaaataaa
    43681 gacaatcact aatgtccagc ccatttctgg attaacatat gcatctgtaa tttttacaaa
    43741 cggatataaa aggtatggca atttactaat tccatagcca aagaacgcga acatcatttg
    43801 taaaataaca aatacaaaag ccaaaccatg ttttttctta aagaatgtta acaatgaagc
    43861 taatgcaaag aataagaaac ttatagcaaa catccaccag tagtcaaaaa cagctgaata
    43921 aaaatgttca gaattttgaa tgcgtaatga tagaaatacg aataaacaaa tgataatcat
    43981 cggtggccct aaaaatatgt gccattgtct tgttaaatta tatgctggtt cgtcatttgc
    44041 ttttttagca taatatgtca aaaatcctga tgaaatatat aaaactgaaa taattgccaa
    44101 gaatactaca gaccaagcaa atgggcttaa tagtaactgc acccaatcta gatcgataac
    44161 attgtttcga acattaatat agccaccttc tgtaatagtt aaagcagtag ataatgaagc
    44221 tggaattaat aatccactta ccccatacat gatcatccat gctaattttg tatcttgacc
    44281 ataattttca aatgcataaa aactgtttct caatgatatc ataatcagtg ctattgaacc
    44341 tggtattaac aataccgtgc ctaaatattt gattgactct ggaaagaaac ctacgaatcc
    44401 tacgaagaag aaaacaaaga atacattcgt aacttcccaa actgggttca aataacgtga
    44461 aattaagtga ttaattttct tttcatcacc agttaacttt gaatgcaatg cgaagaaacc
    44521 tgccccaaaa tctatagaag caataatgat atagcaaaat aaaaacaacc ataacactgt
    44581 tatacctata aatgcataaa tcatttttct atttctcctc cttgcttctt ggctaaacga
    44641 tttacatctt catacgccgg tttattttta aacatacgaa ttaatacgta tgcacatgta
    44701 tacattaaaa tgatgtacaa tatgccaaat aaaattgtaa cgaaggttat tccgcctgct
    44761 tgtgttgctg cttctgccac gcgcatataa ccacgaacaa tccaaggctg tctacccatc
    44821 tctgttaaga accatccaaa ttctatagct agcattgaag ctggtcctgt taataatatt
    44881 ccgtaaagca tccatttatg agtagaaaac tttctaagct ttttaaacat taaagttaaa
    44941 acataaacac ctgaaatgac aaaacataaa attcccatcg ttaccattaa atcaaagaaa
    45001 taatggacaa tcataggcgg atgtaaactt tttggaaaat catttaaccc ttgcacttta
    45061 gttttgacac tattatctgc taagaaactc aatagtccag gtaattcaat cgcaccttta
    45121 acttgctgag tcttttcatc taacacacca aataataata atttagcatg ggaagatgta
    45181 tcgaaatgcc attcataagc tgctaatttt tcaggttgga atttatgcaa aaattttgca
    45241 gataaatccc ctgccaacat agaaagtaaa gttgaaaaga atccaacaat catagacatt
    45301 ttcaaagctt tcttatggta gacagtatct ttaggttgac gattacgcaa taatttaaaa
    45361 gctgctattg atgcaataac aaatgccatc gtcataccgg ctgtagtaat tacgtgaaat
    45421 gatcgaacta taaacgatgg gttaaacatc gcttctatag gttgaacatt gaccatcttt
    45481 ccattcttca actcaaaacc tgcaggcgta ttcataaatg aattcactga agtaatgaag
    45541 aaggctgaga aagagccacc aataattact ggtatactaa ttaagaaatg tgtccattta
    45601 tttttaaaac gatcccaagt atataaatat atacttaaga aaatagcttc aaagaagaac
    45661 gcaaatgttt ccataaataa tggaagtgca ataacgtgtc cacccatttc cataaatgta
    45721 ggccaaatca atgataattg aagtcctata attgtacctg taacaactcc cactgctaca
    45781 gtaattgtat aagctttagc ccatcttttg gccatagcta tatattgaag atcatttttg
    45841 cgaataccta aaaattctgc aattgcgaac attaaaggca taccaacacc aatcgttgca
    45901 aaaatgatat gaactgctaa agtcatagct gtcaaaaacc gactgatttc aactgtatcc
    45961 atttaaaaac atcacctttt tctttttttg atgacaacac aatgaactta attataattg
    46021 ctataatgtg tatttttaaa acattatgcg ctatgaaatt gtgtataatt tatgtcagtt
    46081 cacaatgtgt tcacaaattt gaatttcaat gtataattgt gtatattaca ttagaataaa
    46141 gcacgaagga gcatgataca tgtcagaaat aatcgtttat acgcagaatg attgtccacc
    46201 ttgtacattt gtaaaaaatt atctaaatga gcatcaaatt gattttgaag agagaaatat
    46261 caacaatcaa caatatcgaa acgaaatgat agattttgat gctttttcaa ctccgtttat
    46321 tttgttgaat ggcaatccaa tgtaccatgt tgatcttgat gaaatcaaca aagtattaaa
    46381 tatccaagat taattttcat ctaaatcaac ttcatcattt atagctatca taaattaaat
    46441 atcgattttt aaattaacta acattaatta aagaacaaca ttttgttaat gacacatagt
    46501 tgtttaatta gttagcaaca acattccatt gaaattaaca taaatcataa aaaagaaccc
    46561 gaagtattca taattactca caatgaatac ttcgggttta tttataattc tgtctttcga
    46621 aagaattaat tattttacgt agttgttaac taattcaata acttcttctt gcgttgcaca
    46681 gtcgactgca cggttagcaa gttcagtcat ttcattttta cttaaaccat taatttgtct
    46741 tcttgctttc agaatagacg ttgcactcat agagaactca tctaaaccta aaccaagcaa
    46801 taatggaata gctgtttcat ctccagccat ttcaccacac atacctgtcc atttaccttc
    46861 tttatgtgac gcttcaataa cttgtttaac taaacgtaag attgaagggt tatatggttg
    46921 gtatagatat gatacacgct ctgacatacg gtcagcagct aatgtgtatt gaattaaatc
    46981 atttgtaccg atactgaaga aatctacttc tttagcaaag acatcagcta atgctgctgt
    47041 tgcaggtatc tctaccatga ttcctaattc tatatcatcc gaaatgtcat gaccttcatt
    47101 tttaaggttt tctttttctt ctaataatat agcttttgct tctctaaatt cgttaattgt
    47161 tgcaaccatt gggaacatga tatttaactt accataaact gatgcacgta ataatgcacg
    47221 tagctgtggt ctgaaaatat cttgttgcgc aaggcataaa cgaatcgcac ggtaacctaa
    47281 gaatggattc atttcttcag gcaagtttaa gtatgataat tctttatctc cacctatatc
    47341 taaagtacgt acaacaacac gtttaccgtc cattgcttct aatacttctt tataagcttc
    47401 aaattgttct tcttctgtag gcatttggtc acgacccata tataaaaact cagttctata
    47461 taagccgata ccttgtgcac cattttcaat aacacctggc aaatcattag gtgtaccaat
    47521 atttgcagca agctctgcgt gaacaccatc aactgtaaca gtatcagcat cacgtagttt
    47581 ttgtaattct ttcttgtcag caaaataaca ctcacgttta tcttgataag cgattaactc
    47641 atcttcagtt ggattaacga ttacatcacc atttaatcca tctacgataa tcatgtcgcc
    47701 ttgtttaact tcttgagtaa ttgattttgt accaacaatt gctggaattt ctaaagaacg
    47761 actcataatt gcagagtgac ttgttcttcc gccaatgttt gtagcaaaac cttgtacgaa
    47821 ttctttattt aattgagcag tatcagatgg cgttaagtca ttccctacaa taacaacgct
    47881 ttcatcaatc atactcggat tcggtaattc tacacctaaa atatgtgata acacacgttt
    47941 agaaacgtcg cgaatatcag ccgcacgttc tttcatgtat tcgttatcca tagattcaaa
    48001 aattgtaaca aattgtgttg ttacatccgt taatgctgta gcagcattag cgttttcatt
    48061 tttaatctta tcttggattg gttgaattaa ttcagggtca tctaaaacta ataaatgtgc
    48121 atcaaagata gcagctttat cagcacctag ttgaacctct gcattatttc taattttagt
    48181 taactcaact ttagaagctt cgatagcgct attgaacttt gcaacttctc cttcaacatc
    48241 agtgactttt tcatttttgt cgaatgttaa gtctggctca actaataaat aagctttagc
    48301 aattgcgaca ccatcagatg cagcaatacc tttaattaat ttagacatga ttatttagtc
    48361 aatccttctt ttgataagac gtcactgatt gcttgaatgg cgtcagattc atcactaccg
    48421 tcagcataaa ttgtaatttc agcatcttta ccaacaccaa ggctcataac acccatgatt
    48481 gattttaagt ttactttctt accgttatat tctaattgaa tatcagaatc gaattttgaa
    48541 gctgtttgta ctaacattgt tgctggtcta gcgtgaatac cagtctcgtc gatgattaca
    48601 tatgaatttt gttccataat tacatttctc cttcgtatag ttagaatctt caatattatt
    48661 acaatactaa cttagtttta tacattaact ttaccaaaac catgctttaa attcaattcg
    48721 tttaaaaccg gtttcagtaa aatttgcaaa ttgcaaaact attatagcac ctacatgaca
    48781 tttttaataa cattttcgca tttttgaatg tgatcttttc caattttatt cataaaatag
    48841 taactaatag atgcagacac agcttgtcct acaacaggaa accattttgt ttgttttgca
    48901 gcagtacgtt tagctacatc tctaataact atttttaaaa atgcacttga aattctttta
    48961 ccaataaatt gactaccttg aattgctgct gcagacataa ttctttcttt cacatcatcc
    49021 ccaaggctat taacttgctt atgatctaat ccgtatattt tatttacatc ttcgataata
    49081 tctttcatta attttaaatc aacaccaaaa tctaaacccg gaattggaac aacgctcatt
    49141 gttgatgaca ttaaagactt tctctttaca attgcttcag cacgttgtcg tctttctctc
    49201 aattcttgaa tcgtcgttgg cattgcacct tttccgtcaa cattttctat tttaaagact
    49261 gaattaccaa ttttatttgt taaatttgat gttaaattgt ttttgaatcc cataatatta
    49321 tcacccttct ttttctcaat aagttactat accccttttt atcaaattaa tgtctaatat
    49381 ttacaaaaac agcttttaaa tatttagatg gcttataatg tggatgcgtt ttaaaatctt
    49441 ttggtaaacc cataacttca gttaattcat aatcaacgcc actctcttca agcgtctttt
    49501 taatagtatt tttaaattgc tttaatggat atacacttgc atttgtacat aacaataatg
    49561 ttccttcaga tgataaaata tttaaggcgc cattaattaa tttgtcataa tctttttgca
    49621 ctgaaaatgt acgttttttg ttgcatgcaa agctaggtgg atcaatcacg atcgtgtcat
    49681 aactatgtcc atgtcgtgca gcatatttat agaaatcaaa agtgtccatg acataaatat
    49741 attgggattt aggatcaata gcatttaatc caaaattttc ttcagttaaa ctacgagaac
    49801 gattagccaa atctacactt gttgttgaag atgcctcact tgctgctatt acagaaaaag
    49861 cacctgtata actaaataag tttaaaacat ggcgttcttt ggcatattga ccccttaatt
    49921 tcttgcgcac ttctttttga tctaaaaaga tacctgtcat caaaccatct tcaaggtcta
    49981 cattataaaa tgtgaagttt tcttcgataa caattggaaa ctcaggtgca tcgccttcaa
    50041 caaaaccacc actatattcg ctgtctttaa atcttacttt ttcgtaaata gatttataat
    50101 caaatacttt tctaaccgct tcaagaatgg catatttaaa tttataaata ccttttgagt
    50161 accattgaat caacaaatga ccatcgtaat tgtcgattgt taatccccca acaccatcac
    50221 cttcagcatt aaataatcta aaagcatttg ttccatctat attaaaataa taatcacgtt
    50281 ctgctaatgc agtattaaac aatttcacaa agaaagctgt gttgatttct tgagctttat
    50341 cgtatgttag aacccaacct aatcctttat gttggcgacc aacataagcc gttgcaacat
    50401 attgtgattt atcagtcaca atttgaaaaa tatctccttc ttttaaatga tcttgtgaat
    50461 agatatcctc ttcttcaatt aaaggatatc cattaaaata ttttgtttct ttgcctttgt
    50521 tcagagttgc tattttcatc tgacaacttc ctttctgtgt ttcgttgtag ttttatatag
    50581 attaaattgt ttgccaaatt tcaatatcat ctacttctaa tcttactgtt gattttaaca
    50641 aattagtaat tcgaatgata tatgttaaat ttctacaaag gaaatactat atatcgtttc
    50701 gcaaattcca tatgtcgctt caactattta ctagttttct tgattttaca aatggataac
    50761 ttttcaacta ttttatttgc actaaaactt tgtatacaat tttcaatact taattcacat
    50821 cacctgaatc aatcaaatct agttacaaaa aaagtactat ccataaactt cattgacctg
    50881 tatctaaata agttagagat atatctaact tatagcgtac acatcaaaat gtttaataga
    50941 tagtactttt ataatgcttt taattatggt cgctctcgta attgtaacga ataagaaatg
    51001 atgattgcca ataacattaa tagtaatgtt ggcgtaatga acactgaaag tagtagtcca
    51061 tgaatcatta tatttataaa ttccgttaac aatttaaaga ataaaatgct ccccataaat
    51121 agttgtaaat aataaaactt acctttcaag tggaaagtta acgttgtagc gatatatgcg
    51181 ataataatga ataacagaat taataatgta acccattcaa taacatattg tgtctgtgat
    51241 aatttccaat caccagatac aaataatgca ttacgattat taaattctaa aaatgtgaat
    51301 aaaaagatga cgacaccaca aaatagttcg acatacattg gtttaaccca tttcggtttt
    51361 ctcatccaat caggaatatc gtcttcttga atatcgataa tatcattaac tttctttttg
    51421 aatttatctc ttttagctct aattttatct aaatcgacac ttcttcttgt cttacgtgca
    51481 tattctgtag tcttatcttg gagttgtttc aagtgaattt tagtttgatt cgtgacattc
    51541 cctttacttg ttcttgataa ttctggctcc tcttcaccta attcttgctt tgttaaaggt
    51601 aaagctcggc gcaagaacaa gaaattccaa atagccattt gaccaagtaa ccacataatt
    51661 ataaagaaag cattgacact taagatatca attgactcta tttcattagc atcaattctg
    51721 ccatacaatg caatttgtgt aattaagtaa cttataccat aactcacaat tatccacatg
    51781 aaatgatttt ttacattttc ctgattcaat tcatctttat agacgatata tcctatatga
    51841 attgtaaatg gaataatgaa aatcactgca aagaatccat aaacttgagt cattaatata
    51901 agagtaataa taaagtacat gataccgata actaagaaaa agatagaaat atcatagtca
    51961 tacttaatag ttctaagtaa tgtatgacca atcaacataa ctaaaatacc gaatataatt
    52021 atcacaattg cactaactat agggaaatta cctataaatc gactcattac tttaataatt
    52081 tcactgaaaa atgcattcag aaattcccac acattatgaa catgtgtatc aactttttta
    52141 ccaccattta attgtttaat taatggcaag ttaattaaaa taatgagacc agtgaagagt
    52201 gaaacgatac cgattaaata gctaaaaata atttcggcgt gtttcctaag aaaagacatt
    52261 atgttcacct caaaatcatt atatattaat ctaatgttgt tgtctttaga taaatgaata
    52321 aatagtgcta tagacttaga aaagtttaac gaaagtacaa ccgggtaaga tttatatata
    52381 aataattatc caatttggga ggaattaatc atgtctaatg aaaatcaaaa taaaaaagca
    52441 gcagaaaaag ctaaagaagt tgaagaaaaa ttaaaagata aaaaagaaga aaaaacagaa
    52501 gatattaatc aaacaaaaca agatatccaa gatacactaa attaatttaa atccccttac
    52561 aacttttagt tgttagggga ttttatgcat gtgctcggcg catgtgttcc tcttcttcct
    52621 tacaactttt agttgttagg ggattttatg catgtgctcg gcgcatgtat ccctctttta
    52681 ccttacaact tttagttgtt aggggatttt atgcatgtgc tcggtgcatg tatccctctt
    52741 cttccttaca acctttagtt gttaggggct tttttgcttg cgctcggtgc atgtatccct
    52801 cttttacctt acaactttta gttgttaggg gcttttttgc atgtgctcgg cgcatgtatc
    52861 cctcttttac cttacaactt ttagttgtta ggggcttttt tgcatgtgct cggcgcatgt
    52921 atccctcttt taccctacaa actataattc gtaagccatt atgcacgggt tcttcactgt
    52981 tgttaaagag gtatgattga taagtatccc tcttcattta tcagctcaat cttattacat
    53041 gtcacatatt tttatatctt taattactaa cattcctact acatcttcaa tttaaatcca
    53101 atgctaatat tataaatttt aaatcgaatt aaacgaaatt tcatgaagac aacctattga
    53161 cataagttta caaacgtctt acagtataat taattaaata aatcgcacac actaggggtg
    53221 ttttatactg agatgaggct tgccctcaaa ccctttgaac ctgatctagc ttgaactagc
    53281 gtaggaaagt gttactatac atatgtttta ctaatatata ttgtgaacgc ataactttcc
    53341 tatggatggt tgtgcgtttt tttattagga ggatgtaaaa atgtcaaaag gtttaaagct
    53401 atctgaaata ctagtaaccg tacttatttc agtagtattc gcagttattt acaatttatg
    53461 gtggtttgtt tacaatggtg tgcaagctac aggccttcac ctcgaacaat taacaaacgg
    53521 ggtttggttc atggcagcga ttgtctgcta tctaattatt ccaaaaccag gtattgcttt
    53581 actggctgaa tttgctgcag gtgccggcga aactatcatt atgggtcgtt tcgatattcc
    53641 gacaatcgtt tacgctttca tacaaggttt agcgtgtgaa cttgtctttg caatttttaa
    53701 atatcaatct cgttcagtta tggtagctat gttagcaggt ttttgtacag caatcgcggc
    53761 tttccctata gattatttct atggttattt aaatgaagtt gcaggttgga acttaacatt
    53821 attcatcgta tttagattaa ttagtggtgc agtagtcgcc ggcgtcctat cttacctttt
    53881 agtaaaagct ttagataaga caggcgtaac aaaattattt agaccagctg ctaaagaaga
    53941 ttacgacaac ttataagagg agcattcaga gtgttaaaag taagtgattt acgattaaaa
    54001 tatccaaatg gtcagcgtaa aattttcgat catttaaata tcactattca agacaaagaa
    54061 aaagtacttt tactcggtcc ttctggttgc ggtaaaagta cacttctgaa tgtattaagt
    54121 ggtattgttc ctaatttaat tgaattacct atgaaatatg atgaactaat cgttgaccca
    54181 ttaagtggcg ttattttcca agaccctgat agccagtttt gtatgccaaa agtatacgaa
    54241 gaacttgcat tcgttttaga aaatagacaa gtaccacgtg aagacatgga tgcgttaatt
    54301 atcaatgctt taaatatggt caatttaaat gttacccctg aaacgtatat caaagattta
    54361 agtggcggga tgaaacagaa attggcaatt gttgaaacca ttcttcaaca atcaaaaaca
    54421 ttgtttttag atgaaccgac agcaatgtta gatgttcaag caacagaaga tttatggact
    54481 aaactaattg aactttggga agatcaaact gttgtaatcg ttgaacataa agttaaacac
    54541 atctggaatc atgtcgaccg cgtcattttg atggattata acggaaatat cattgccgat
    54601 gaatgtcctg aaatcatatt acagaagtat gttcatttac tcagtgaata tggtgtgtgg
    54661 catccacgtg catgggaatt cgcaccaagt cgtgttgact ttccaacaac aaactcacac
    54721 ttattacaat ttaaaaatgg acgtattatt cgcggtaaat caacattgct ctcattctca
    54781 gatttagaaa ttggtctagg tgagtggatt acaattacag gggcaaatgg tagtggtaaa
    54841 acaaccttgc ttgaatcaat tatgcaattg attaaatatc aaggtgatgt ttattttgaa
    54901 aatcagcgtt taacaaaaat taaacatgca gcaaaacaca tgtacctagt ttatcaaaac
    54961 ccagaattac aatttataac aaattcggtt tatgatgaaa ttaacattca ttttaatcac
    55021 ctttctaaag atcaaagtga tgatgaaacg atacaacttt taaaactttt agatttacaa
    55081 aatgtaaaag atcaacatcc ttatgagttg tctattggtc aaaaacgacg ccttagcgta
    55141 gctaccgcac taagttctaa agctgatatt atctttttag atgaaccgac atttggactt
    55201 gatagccata atacattcca gttgatcaaa cttttccaaa agcgaattaa tttgggacaa
    55261 agtattgtca tggttacaca tgacgatgaa ataattgaac gttatccatc aagaagactt
    55321 aaaatttcag atggtgcgtt actagattgt gatggtgata cgaatgtatg agcaatggaa
    55381 agttcggcaa tcatttgttg atgatgtcaa cattataacg aaactatttc ttggaattat
    55441 actatttttc tttattatat ttgtgcataa tttcgatttt atgctttata tcactatctt
    55501 aatgttagtt ttcttattga tgtttaatgg tactcagttt aaaattacag caatttttat
    55561 aactataagt attggctttg cattactctc ttccctgttc atgattttat acgggaatgg
    55621 tagccataca attttgaaat tcggatttat ccatattaca acagaaagtt tagttcgtgg
    55681 tttacatgta tcattaagaa ccattgctat ttcatttttc ggtatcttaa tcgcacttac
    55741 atctcaggtt gtcatgatat tttatagttt aatgcaacat ttaaaggtta aatcaaaagt
    55801 tgcttatgca ttcatggctg ccattcgtat gataccttta atgattagtt ctttaataca
    55861 gcttcgcaga tctttaaaaa tgcgctatca gatgatagac gcagcaaatt atagagggtt
    55921 aaagagattt aagcatttaa ttatacctct attaagccaa aatattagaa aggcacatca
    55981 attatcagtt gcgatggagt cgaaaggatt tagagatggt cctcgtactt actattacaa
    56041 cgtacctttc tcatataaag atataatctt tattatagtt ttaattgcca ttattactat
    56101 ggcatattat tgttcaatca ccttacccat cacgggcata gatgatgttc gtcttgatcg
    56161 tgtaggttaa attttatcca taattgtata gatactaaat tagaaattca ttgtatagaa
    56221 aaagaaaacc atttattcca tactaaacaa aagaggtgcc acaaacatgt tattttgttc
    56281 atccaaacat gttgtggcgc ctcttttgta ttacatatgc ataatcacaa atttggtaca
    56341 gaaatcaatg tcctagactc tacaactaaa aaagctatga aaaaaactat cgttatagat
    56401 ttcttcatag ctaatcttag tattttttaa atatacttat ttaagttgta gtgctttatt
    56461 cgcaatgtca tgacgataga ataaatggtc actttgtatt tgagatactt tttcgtatgc
    56521 gtctcgctgt gcatcttgta cattgtcacc ttttccgatg gcaagtataa ctctaccacc
    56581 tgaagtaaca aaggtatcac cttgcttctt taatccacta acaaaatagt tttcatttaa
    56641 atcaaagcca cttactttat gccctttttc atatgcatca ggatatcctt ttgatgccaa
    56701 catgacccct acaatagatt catttttcca tttgaattca gtacgttttc cttcatctaa
    56761 atcaataata tgctgcatta aatcactttc catgcgactt aataatactt gagcttcagg
    56821 atcaccaaaa cgggcattaa attctattac ttttggacca tctttagtta aaatagcacc
    56881 aatgtataat acaccgaaga attgataacc ttcattaagc attgcctttg caatgggttg
    56941 tgcaattgtt tcatttgtaa gttttaaaac atcgtcacta atatgtggta ctggacaata
    57001 agcccccata ccaccagtat ttggtccttc atcatgatca aatgcgcgtt tatgatcttg
    57061 tgcaatacag tcgaaaggta ctgctaaatc accattaaca aatgtcatta gcgagaactc
    57121 ttcaccttct aaaaacgttt caaatacaac agtaccttct tcttcatcac catacataat
    57181 ctcaatagca cttctggctg cttcaatagt atctgcaata ataacgcctt tcccagcagc
    57241 taacccatct ttcttgacaa caacgggcaa ttcacagttt tcaatatatg ttaaagcatc
    57301 cttttttcgc tcaacttctt tataatcagc agttggaata ttatattttt tcattatctt
    57361 tttagcaaat aattttgagc cttcgatttg agctgcttgc ttatttggac caaacacttt
    57421 gaaaccattc gctcgtaaaa tgtctgctaa tccatcaatt agcggctgtt ctggacctat
    57481 aactacccaa tcaacatttt gctgtttagc aaaatctagt atcccttgat gattagattc
    57541 tgaaatttca gtgtgtactt cagctatagg tgtcattgcc tcattacctg gaatgacaaa
    57601 ctcttgttta actagattcg attgattaag tttatatgca agtgcatgtt ctcgtccacc
    57661 agcaccaatt actaatacat tcatttatgt tacgcccctt taaaattagt gtttaaaatg
    57721 tcgagtgcct gtgactacca ttgcaatacc atgtttatta gccatatcaa ttgaatcttg
    57781 atctttaatc gaaccacccg gttggataat tgcctttata ccatgttgtg ctgcaagttc
    57841 aactgtatct cccataggga aaaatccatc agatactaac gctacatgat cattgatttc
    57901 aatagctctc tctaacgcaa ttttagcagc accgacacga ttcatttgtc cagcacctat
    57961 acctacagtt tgtttattat tacttaaaat aattgcatta ctttttactg atggtacaac
    58021 tttccatcct aataacattg cttcccattg ttcatcagta ggtgctactt ctgtaacaac
    58081 tttcatttct tcttttggca cgacataatt gtctttatct tgaactaaat atccgccaga
    58141 tactgaaaca aactcttctt cgttactgtc tatagtcata tcaatttcta ataatcttac
    58201 attcttcttt tgttttaaaa tatctaatgc ttcatctgta aattttggtg caataatgac
    58261 ttccaaaaag atactatgca attgctctgc taactcaggt gttacagctc ggtttaatgc
    58321 aacaattcca ccaaatattg attgactatc cgcttcatac gcatgttgaa atgcttgttc
    58381 aatcgtgtca ccgataccaa caccacatgg attcatgtgt ttaaccgcaa ctgcagcagg
    58441 tgtatcaaac tttttaacta aagctagtgt agcatctgca tctttaatat tgttatagct
    58501 taattgtttc ccatgtaatt gtttagcacc tgcaatcgtg tgcttagcat tcgaagttct
    58561 cacaaaatac gctgattgtt gtggattttc tccatatctt aaagtttctt tatccccttt
    58621 aaagaaacgt acaatcgctt catcatattc tgcagtatgc tcaaaaactt taatcattaa
    58681 tgattgtcta tatgactcat ctaacgaatc gtttcttaat cgcgtcaata cttcatgata
    58741 atctgccgga tgtacaattg ttgttacatg tttatagttt ttagctgcag cacgtaacat
    58801 tgttggacca ccaatatcaa tattttcaat tgcttcgtcc atcgtcacat cagggtttgc
    58861 aacagtttgt tggaatggat ataaattaac tactaccata tcaattaaat ctatatgttg
    58921 ttctgataat tcatttaaat gctgcggttt atttcgatca gctaaaatgc caccatgaac
    58981 agccggatgt aatgttttaa cacggccatc cattatttct ggaaaatgtg ttaagtctga
    59041 aacagaacga actggtacat ttgcttcatc taatatacgt ttagtaccac cagttgaata
    59101 taattcataa tttaattgcg ttaacgcttt agcaaactct acaatacctg ttttatttga
    59161 tacgctcaaa atagctttct tcatcacata catactcctt attttacaat tttagcaata
    59221 acacttggat ataactcata ttccaatttt tttactttct cttctaattg ttcttttgaa
    59281 tcgtccggtc taatatcaca ttgtctctgt tcaataattt ctcccgtatc cataccacaa
    59341 tcaacataat gtactgtcga accagtaata gtatcgccac tatgatatgc ttggcctatt
    59401 gcgtcaatcc ccttatattt cggcaataga gatggatgta tattcaatat tttaccttca
    59461 aatgaagcta ataaatctgg accaattaga cgcatgtagc cagctaaaat aatccactct
    59521 accttatctt tatttaataa tgttactaaa tgttgttcat acgctgcttt tgaatcaaat
    59581 tgttttggtt cattaatata aacaggaata tcgtgctttt ttgctctatc tatacaaaac
    59641 gcattttgat gatccgtata tagcgccgta acttcaatat tttcaagttt tcctgattca
    59701 acatgctcaa ctatattttc aaagttactt cctgaacctg atgcaaaaat cgcaatttta
    59761 accattgtta tacccccaac aattcaattg cagttgactc atttttcaca atatgaccaa
    59821 tttgataagc ttccacattt tgttctgcta aaatcttcaa agcgcgtgat gcatcttttt
    59881 catcaacgat aaccgtatag ccaataccca tgttaaaaat gttatacatt tcatttgtgt
    59941 ctatattgcc ttgttgttgt aaccaatcaa atatttttgg cgttggaaat gatgtagtat
    60001 caattctagc agcatatccg gctggcaatg cacgtggaat attttcataa aaacctccac
    60061 cagtaatatg attcattgcc ttaatagaaa cttctttttt taaagcaagt acaggtttga
    60121 catataattt agttggttct aaaaagacat ctataaatgg acgattatcg aagtttgatg
    60181 ccaaatcaat gcctgattca ttaattaatt tgcgcactaa actgtatcca tttgaatgaa
    60241 tgccacttga cgcaagtcct ataacaactt gtccctcttt cacttctgaa ccatctacat
    60301 agtcatcctt ttcaactgct ccaacagcaa atccggctac atcatattca ccttcgtgat
    60361 acatttcacc catttcagca gtctctccac cgataagtgc agtattcgtt tcaacgcatg
    60421 catcactaat acctttaaca atttgttcaa taacttcagg aacaacttta tttgtagcga
    60481 tgtaatctaa aaaatacaat ggttctgcac ctgtcgttaa aatatcatta acacacattg
    60541 caactgcatc gatacctatc gaatcatgtt tcccatagtc gatagctagt tttaatttcg
    60601 tacctactcc gtctgttcca gaaactaaaa ctggcgctgt catatttaat tgtgataaat
    60661 caaatgtagc accgaatcca cctaaaccac cgataacttc tttacgcatc gtacgtttaa
    60721 catgactaga cattctttct acagcttcat aaccagcatg aatatttaca ccagattgtt
    60781 catatgcttt agacatttaa atttccctcg ctatcaaaaa agtgtttgtt tttagaaata
    60841 tattgctttt gtcgatgact taaatgtgct ttataatttg cttcataatc atataaccct
    60901 gcaggataat ctccagtgaa actttctaca cataagccac tatatggcgc gtcataatct
    60961 aaaccaattg attcaattaa cccatctaca gatagatatg ctaatgaatc agcgccaata
    61021 taatctttaa tttcttcagg tgatttgctt gcagaaatta attctgccgt agttgaaaca
    61081 tcgattccat aaaaacttgg gaacataaat tccggtgatg ctatacgcac atgcacttta
    61141 tttgcaccag aatcttttaa cattttcaca atgcgtcgaa ttgtcgtacc gcgaacaatg
    61201 gaatcatcaa caagaatgat atttttccca tctactatat cttttaccgc agataacttc
    61261 actctcacac cttgctcacg taattcttga gttggttgaa taaatgttct tgcaacatat
    61321 tgatttttaa ctagtcccat ttcatatggc aaacctattt cttcagcata accactcgca
    61381 gctgatagcg atgaattggg tacaccgatg accatatcag catttacagg gctttcttgg
    61441 gctaattttt taccagaagc tttacgtact gcatggacat ttttaccagc tattgttgag
    61501 tctggtctag caaaataaat atattccatc gtagaaattg cagttgtcgt atgatgtgta
    61561 taagatttaa ctgtaatacc tttatcgtta atcacgacat attcacctgc atgaatatct
    61621 tgaacaaatt ctgcacctaa cacatctatt gcacatgttt cacttgcaag gatgtatgta
    61681 ccatctttca ttttacctac aacaagtggt ctgatagcat ttggatctac tgcgccatat
    61741 aacgcatctt tagttaatat cgcaaatgta aaaccgcctt taacttttcg caaactttct
    61801 ttcaatgctt cctcaaaagt aggagcttta cttcgacgta tcaaatgcat aatgacttca
    61861 gtatctgaag acgaatggaa gatagcacct tgtttttcta aattctgacg caatgattta
    61921 gcattaatga ggttaccatt atgacaaata cctacactca tatcataaaa gtgatacaga
    61981 aacggttgaa tattttcaat acctttatta cctgaagtag cataacggac gtgaccaatt
    62041 gcatgttgat atccttttaa tcgttccatt tgatcatcgt taatcgcttc agttagtaag
    62101 cctaatcctc gctcgccttt taattcattt tgatcagaaa caactatacc tgcaccttct
    62161 tgaccacgat gttgcaaact atgaagtccc atatatgtta gttgcgctgc ttcaggatga
    62221 ttccaaatac caaacacgcc acattcttcg tttaatcctg agtagttaaa cattgagcaa
    62281 ttgccccttc ccatatttgt ttaatatctg aaacattttc actaatctct gtatatggtg
    62341 ttgttacttt gaaattatca ctatctgtta aaagtccaat ttctattgca ttatcaatat
    62401 ttaaagtttt acctgattta acagaaacaa catatcggcc ttgtgtctca ctaaacaatt
    62461 gtgcatttgt tatatctatt gaagatttta atcctaaacc gtaatgcgca cttagtttag
    62521 ctaaggtaat cagtaagcca cctttaccaa ctgtttgaac atgtgataat agtccttcac
    62581 gaatagcggt cttgattgat tcaccttttt caacttctga actcaaatct aatgactcaa
    62641 attcatgatt aactttgcca taaattaact tttcaagttg actaccacca aagtcgtcct
    62701 tagtatcacc gattaaatat aatttatctc caacttgagg ttcaaaatca tttaaataat
    62761 ttacattttc aatcaaacct accattccaa caactggtgt tgggaaaata gaagtacctt
    62821 tcgtttcgtt atataaagat acatttccag aaactactgg tgtcttaaga atgtcgcatg
    62881 cttctgccat acctttcgtt gaatctatca actgttgata gatttctttc ttttcaggag
    62941 aaccataatt taaacaatct gtcattgcta atggtgttgc acccacggca attaaatttc
    63001 gataagcttc agctactacc atctttccac cttcatatgg attgttatat acataacgcg
    63061 cttcaccatc aattgttgaa gcaattgcct tatttgtgcc ttccacacgt actaccgatg
    63121 cttgaagtcc tggcttaatt atcgtattgg caccaacttg ttggtcgtat tgatcatata
    63181 aatagtgttt agatgctata gtcggatgct taagtaattt aaagaaagta tctttaacat
    63241 cgatgtgtgt ataatcattt ttagaagtat tataatcttt ttcttctcct tctaaaatat
    63301 atacaggtgc ttcatcagct agtggttcaa ctggaatgtc agcataaact tcatcatcat
    63361 atgttaaaac aaaacgattt gtatctgtaa cttcacctat aacagcacta tccaattcgt
    63421 gcttatcaaa taaatctaag aatttttgtt cattaccttt ttcaacaact agtaacatac
    63481 gttcttgagt ttctgaaagc atcatttcat aaggagaaat acctggctca cgtgttggca
    63541 cttgttctaa tctcaaatgt aacccactac caccttttgc cgccatttca gacgatgaag
    63601 atgttaaacc agcagcaccc atatcttgaa taccaactaa ttcatcaaat gtaattgctt
    63661 caagtgttgc ttccattaat tttttaccta caaatggatc accgatttgt acagaaggtc
    63721 gtttactttc gctttcttcc gtcaattctt cagatgcaaa agtagcacca tgaataccat
    63781 ctcgaccagt tttcaaacca acataaatga ccgaattacc tacacctttt gctgtgcctt
    63841 tttgaatcat gtcgtgattg ataacaccaa cacacattgc attaacaagt ggattgccat
    63901 cataacgttc atcaaattcg atttcaccag cagttgttgg aataccaatg cagttaccat
    63961 aacctccgat accctttaca acccctttaa gtaatctttg gttttgttta ttatctaatt
    64021 ctccaaatct aagactgttt aacaaattaa taggtctagc cccaatagaa acaatgtcac
    64081 gaatgattcc accaacgcct gtagcagccc cttgatatgg ttcaattgct gatggatgat
    64141 tgtgagactc tactttaaat actacggctt gattatcacc tatatcgact acccctgcac
    64201 cttcacctgg acccataagc acatgctcac ctgacgtagg aaattgcttt aaaaacggtt
    64261 tagaatgttt ataagagcaa tgttcactcc acataacaga aaagatacct gtttctgtaa
    64321 agttaggttg tctgcctaaa atatcgcaaa ctttttcata ttcttgatca cttaatccca
    64381 tatcttgata tactttttca agtttaattt cttcaacgct tggttcgata aaattagaca
    64441 tgttgttccc tccaactttt taccatcgct tcaaataatt tcacaccact atcagtacct
    64501 aacaacgttt ctaaagctct ttcaggatgt ggcatcatgc cacatacatt gcctttttcg
    64561 ttaacaattc ctgcaatatc atcatatgaa ccgttcggat tattcacata tttcagaata
    64621 atttgattgt tagcttttaa ttgttgatat atttcatcag tacaataata atgaccttca
    64681 ccgtgagcta caggatatat aactttttca ccttgctcat aaagatttgt aaatgccgtt
    64741 tgattattca ctatttctaa ctcttcattt ctactaataa ataaatgtga atcgttatgc
    64801 aataatgcac caggtaataa gcctatttca gttaaaattt gaaacccatt acaaacacct
    64861 aatactggct taccttcagt tgcaagacgt ttaacttccg aaataatcgg cgctacacta
    64921 gccattgccc cagatcttaa gtaatccccg aatgaaaatc caccaggaat aagtacgcca
    64981 tcaaatccac ttagtgatgt ttctctataa tctacatatt ccgcttcaac accactttta
    65041 atagcagcat taaacatgtc tctatcacaa ttcgaacctg gaaaaacaag aaccgcaaat
    65101 ttcattttat gcattctcct tttcatcatc taacacttta tagctatatt cttcaatcac
    65161 tgtatttgca aacaattttt cacttagagt tgtaataatg ttgtgtacct tttcatcact
    65221 aacctcatcc actgtcatat ataatacttt tcctacacga atatcattca cttgtgcata
    65281 acctaagtca tgtacagctc gagtaagcgt ttgtccttgc gtatctaata cttgtggttg
    65341 taatgtgata tgtagttcaa ttgttttcat tattttaaat cctccaattt gtttaaaaat
    65401 atttgatatg tttcaatcag tgatccagtg ttatttctat atacatcttt atcaaagttt
    65461 gcattggtag ctttatccca aattcgacat gtatctggag atatttcatc cgctaacaaa
    65521 atttgaccag tctcagtctt tccaaattcg attttaaaat ctactaattt taaattcata
    65581 gcatccatta attgtttcaa cacattatta atctttaatg ctttggattt tagtatttca
    65641 atatcttcat ctgatgctat attgagcaat ttaacatggt catccgttat caacggatca
    65701 tttaacgcat catttttata gaaaaattct acaagtggtt ctctaaaaac ttcaccattt
    65761 tcaaaaccta aacgctttgt aatagatcca ctagcaatat tacgaacaac tacttctaat
    65821 ggaattattt tcacaggctt aactaattgt tctgtttcag ataattgttt aataaagtga
    65881 ctttctattc cattttcttg taaatattta aatataatag aagtaatttg attatttaat
    65941 cgccccttac ctgccattgt gtctttctta gccccgtttc cagcagtaac ttcatcttta
    66001 tattcaactc ttaattcatt ttcttgattt gttgagaaaa tgcgcttcgc ttttccttca
    66061 tataataatg tcatgcttta attactcccc tcaaatttag cgtacatatc ttgttcagtt
    66121 tggtttacat cattcgttag tacagtcata tgccccattt ttctgctatc tttacgccca
    66181 gacttaccat aaatatgtaa gtgccactct ggatgttcat taaattcatt ttccaataaa
    66241 tctaagtctt tacctagtaa gttcatcatg actgcaggct ttaataattc aattgaattt
    66301 ggtaatgatt gtccggtaac tgctaaaata tgagtatcaa attgtgaata atcacatgct
    66361 tcaattgaat aatgtccgga attgtgaggc cttggtgcaa tctcgttcac atacaattgg
    66421 ttgttactat ctataaaaaa ttccactgta aatgttccaa tgaaatgaat cgattggata
    66481 attttattaa cttgctcttt cgcctcagct gttttatcta ttctcgctgg aacaattgtt
    66541 ttgaaaagta tttgatttct atgctcattt tcttgtaatg ggaaaaaagt gatttgattg
    66601 ttgtttcctc ttgtaacagt aagagatact tctttcttga tattcaaata tttttcagct
    66661 acgcattcac tagtttcaat taatttaaaa ccttcttgta agtctttttc gttgttaatt
    66721 aaaacttgac ctttgccatc gtagccacca aatctagttt ttacaataaa aggatatcct
    66781 aatgtttcaa ttgctttgtc aatatctgta gattctttta ctgaaatgaa cgggacaact
    66841 ttggtaccag cactttttaa tgtttctttt tcagttaagc ggtcttgtaa taactgtata
    66901 gcttggtaac cttgcggaat attgtacttt tcacataata gttttaattg ttgggctgaa
    66961 atgttttcaa attcataagt aatcacatca catttttgtc ctaattgatt gagtgccttt
    67021 tcatcgtcat acttggcttg tataaattcg tgtgcaacgt atctacatgg acaatcttca
    67081 gaaggatcca atacaaccac tttataaccc attttttgag ctgattgtgc catcatcttt
    67141 ccaagctgac caccaccaat aatgccaata gtcgcaccaa actttaattt attgaagttc
    67201 attttgcatg tcctccactt tttgaattaa cgaagattca tactgattta gtttttcaac
    67261 taaagaagga ttttgaatac ttaacattct tgctgcaagt atacctgcgt ttttagcacc
    67321 tgctgcacca attgcagtcg ttgcaaccgg aatacctcct ggcatttgaa caattgataa
    67381 taaagaatct atacccttta aactttttgt ttcaatcggc acaccaataa ctggtagcgt
    67441 cgttaatgat gcaaccatac ctggtaaatg tgccgcaccg ccagcgcctg caatgataat
    67501 gtttatacct ctttctctcg cttcagaagc aaattgaacc atcatttttg gcgtacgatg
    67561 tgcggatact acttgttttt cgtacggaat ttcaaaataa tccaacatgt tacaactctc
    67621 ttgcataatt ttccaatcgg aagaactgcc cataatgact gctactttca ctttgtacac
    67681 cctttcaaaa gtttgaattg tgaattactt tagttgtata ttatagatat agcataacaa
    67741 gcaatttctg ctttttcaat ctaaaatcga actttatttt gattttttgt ttgaatttac
    67801 gtcttttgct atgtaaatta gttttataaa ctaacaaagt taggatattg acaataggag
    67861 gagaagtttt tatggttgct aaaattttag atggtaaaca aattgccaaa gactacagac
    67921 aggggttaca agatcaagtt gaagcgctaa aagaaaaggg ttttacacct aaattatccg
    67981 ttatattagt tggtaatgat ggcgctagtc aaagttatgt tagatcaaaa aagaaagcag
    68041 ctgaaaaaat tggtatgatt tcagaaatcg tacatttgga agaaacagct actgaagaag
    68101 aagtattaaa cgaactaaat agactaaata atgatgattc tgtaagtggt attttggtac
    68161 aagtaccatt accaaaacaa gttagcgaac agaaaatatt agaagcaatc aatcctgaaa
    68221 aagatgtgga cggatttcat ccaataaata tagggaaatt atatatcgat gaacaaactt
    68281 ttgtaccttg cacaccgctc ggcatcatgg aaatattaaa acatgctgat attgatttag
    68341 aagctaaaaa tgcagttgta attggacgaa gtcatattgt cggacaacca gtttctaagt
    68401 tactacttca aaaaaatgca tcagtaacaa tcttacattc tcgttcaaaa gatatggcat
    68461 catatttaaa agatgctgat gtcattgtca gtgcagttgg taagcctagt ttagtaacaa
    68521 aagatgtggt caaagaagga gcagtaatta tcgatgttgg caatacgcca gatgaaaatg
    68581 gcaaattaaa aggtgacgtt gattatgatg cggttaaaga aattgctgga gctattacac
    68641 cagttcctgg tggcgttggt ccattaacaa ttactatggt attaaataat actttgcttg
    68701 cagaaaaaat gcgtcgaggt attgattcgt aaagagcctg agacataaat caatgttcta
    68761 tgctctacaa agttataatg gcagtagttg actgaacgaa aattcgcttg taacaagctt
    68821 ttttcaattc tagtcaacct tgccggggtg ggacgacgaa ataaatttta cgaaaatatc
    68881 atttctgtcc cactccctaa taactgagtt ttaatgaact cttttaaccc acattaaata
    68941 ttattttgca attgcaatga ataacaagaa aaacctggga cattaatcga tcaaatgctc
    69001 ccttcaaagt agacattgaa taaatgaagg ctttgaaggg agcatttcac tttgttcttg
    69061 gctcaacaat tttatataga cagtagttaa ttgaatgaaa ataagcttgt aacaagcatt
    69121 tttcaattat agtccggggc cccaacacag agaatttcga aaagaaattc tacagacaat
    69181 gcaagtcagc gaggccccaa caaagaagct gtgactatga taaagtacta ctacatagtt
    69241 aatcattagt ggttctttat cattttcgcc tcccttttct tattgttttg atacacaaaa
    69301 atttaagttc aaactgtcga ataaagttat atttgatttc aaattatccc taaattatta
    69361 attttacaat tgtggcagat tttcaaaata ataattat
//
LOCUS       DAPDIM010000006        68629 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000006 DAPDIM010000000
VERSION     DAPDIM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 68629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68629
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.006"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..275
                     /locus_tag="RFE25_000418"
     CDS             <1..275
                     /locus_tag="RFE25_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TIGR01741 family protein"
                     /protein_id="HDU2815518.1"
                     /translation="DLYRLFKKLRNAFKEEDLEPWTSCEFDFTSEGKLKVSFDYIDWI
                     NTEFDQLGRENYYMYKKFGVIPEMEYEMEEVKEIEQYIKEQDEAEL"
     gene            286..771
                     /locus_tag="RFE25_000419"
     CDS             286..771
                     /locus_tag="RFE25_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01741 family protein"
                     /protein_id="HDU2815519.1"
                     /translation="MIFEEKLSQMYNEIANEISGMIPVEWEKVYTIAYVDDEGGEVVF
                     NYTKPGSDELNYYTYIPREYNVSEKVFYDLWTDLYRLFKKLRNAFKEDLEPWTSCEFD
                     FTREGNLKVSFDYIDWIKLGFGPSGKENYYMYKKFGVLPETEYEMEEIREVEKYVKDQ
                     E"
     gene            1397..1771
                     /locus_tag="RFE25_000420"
     CDS             1397..1771
                     /locus_tag="RFE25_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4467 domain-containing protein"
                     /protein_id="HDU2815520.1"
                     /translation="MKRILVVFLMLAIILAGCSNKGEKYQKDIDKVYKEQNQMNKIAS
                     KVQNTIKTDIKQEDSNTHVYKDGKVIVIGIQLYKDREKMYYFAYEIKDGKAEINREID
                     PIKYMKDHKADYEDENVEVEKD"
     gene            1921..2319
                     /locus_tag="RFE25_000421"
     CDS             1921..2319
                     /locus_tag="RFE25_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDU2815521.1"
                     /translation="MEKSIKIMTIIGIVIQGLATVFSLLLMVLAASGVMTTDVSTTVN
                     GEVDPVDAETAAAIFTVLFLSLFIFGIISIILGAIGMFKASKNKKMSGILLIIGAVIS
                     GNIITFALWLVSGIKLLTNNKPKDEISDLS"
     gene            complement(2535..3359)
                     /locus_tag="RFE25_000422"
     CDS             complement(2535..3359)
                     /locus_tag="RFE25_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDU2815522.1"
                     /translation="MKEKHIKWDKIFYGDDWVNNVVETIRTKDILQSVYLKRYLLRAM
                     MAGFIIGIITVFVLSVKATHEPDLPPGIVNMASAITFSFALVLILFTNSELLTSNFMY
                     FTVGLYYKVIKPTRVLKIFLLCFAGNILGAAILFSFMRFSNVMTPDMLNQLSAVIEHK
                     TLSTGFVSILMKAIFANFFINISLVIAMQIDDVLAKMFVMMFGVTIFAFMGYEHVVYN
                     SCLFMGGLIYQVDTLHFIPAISNITAAFIGNYIGGGLIIGLFYAYLNDHHQFYKNN"
     gene            complement(3596..4903)
                     /gene="brnQ"
                     /locus_tag="RFE25_000423"
     CDS             complement(3596..4903)
                     /gene="brnQ"
                     /locus_tag="RFE25_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDU2815523.1"
                     /translation="MKKQVIISGLMLFSLFFGAGNLIFPPILGHTAGQNMWIGMLGFA
                     LTGILLPFITVIVVAFYDEGVESVGNRIHPWFGFIFAVVIYMSIGAFYGIPRAANVAY
                     EIGTRHILPVHNQWTLIIFAAIFFAIVYWISLNPSKIVDNLGKLLTPLLLLMVALLSI
                     AVIFNPESALSAPKDKYITHPFISGSLEGYFTMDLVAALAFSVVIVNGYKFKGLTDRM
                     KILKYVCFSGLIAAILLGMIYFALAYVGASTAPGNFKDGTDILTYNSLRVFGSFGNIV
                     FGMTVILACLTTCIGLVNACATFTKKHVPKFSYKIFALIFSIIGFLFTTLGLEMILKI
                     AVPLLTLIYPVSIALVLISFANMFSTFRFSWAYRLATVITLIISILQILNSFNLLHGV
                     ILKWFMMLPLADIDLAWLVPFMLFAIIGFIIDVVIRRPKQATT"
     gene            5487..6377
                     /locus_tag="RFE25_000424"
     CDS             5487..6377
                     /locus_tag="RFE25_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HDU2815524.1"
                     /translation="MNKISKYIAIASLSVAVTVSAPQTTNSTAFAKSSAEVQQTQQAS
                     IPASQKANLGNQNIMAVAWYQNSAEAKALYLQGYNSAKTQLDKEIKKNKGKHKLAIAL
                     DLDETVLDNSPYQGYASIHNKPFPEGWHEWVQAAKAKPVYGAKEFLKYADKKGVDIYY
                     ISDRDKEKDLKATQKNLKQQGIPQAKKSHILLKGKDDKSKESRRQMVQKDHKLVMLFG
                     DNLLDFTDPKEATAESREALIEKHKDDFGKKYIIFPNPMYGSWEATIYNNNYKASDKA
                     KDKLRKNAIKQFDPKTGEVK"
     gene            6626..7675
                     /locus_tag="RFE25_000425"
     CDS             6626..7675
                     /locus_tag="RFE25_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815525.1"
                     /translation="MFLAWNEIRRNKLKFGLIIGVLTMISYLLFLLSGLANGLINMNK
                     EGIDKWQADAIVLNKDANQTVQQSVFNKKDIENKYKKQATLKQTGEIVSNGHQKDNVL
                     VFGVEKSSFLVPSLIEGHKATKDNEVLADETLKNKGFKIGDTLSLSQSDEKLHIVGFT
                     ESAKYNASPVIFTNDATIAKINPRLTGDKINAVVVRDTNWKDKKLNQELEAVSINDFI
                     ENLPGYKPQNLTLNFMISFLFVISATVIGIFLYVMTLQKTSLFGILKAQGFTNGYLAN
                     VVISQTLILALFGTAFGLLLTGVTGAFLPDAVPVKFDVLTLLVFAIVLMIVSVLGSLF
                     SILTIRKIDPLKAIG"
     gene            7688..8365
                     /locus_tag="RFE25_000426"
     CDS             7688..8365
                     /locus_tag="RFE25_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815526.1"
                     /translation="MLKFENVTKSFKDGNRNIEAVKDTNFEINKGDIIALVGPSGSGK
                     STFLTMAGALQTPTSGHILINNQDITTMKQKALAKVRMSEIGFILQATNLVPFLTVKQ
                     QFTLLKKKNKNVMSNEDYQQLMSQLGLTSLLNKLPSEISGGQKQRVAIAKALYTNPSI
                     ILADEPTAALDTENAIEVIKILRDQAKKRKKACIIVTHDERLKAYCDRSYHMKDGVLN
                     LENETVE"
     gene            8573..9604
                     /locus_tag="RFE25_000427"
     CDS             8573..9604
                     /locus_tag="RFE25_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDU2815527.1"
                     /translation="MDLMIGTLFLFLVLVIFTLFTYKAPNGMRAMGALANAAIATFLV
                     EAFNKYVGGEVFGVKFLEELGDAAGGLGGVAAAGLTALAIGVSPVYALVIAAACGGMD
                     LLPGFFAGYMIGYVMKYTEKYVPDGVDLIGSIVILAPLARLIAVLLTPVVNSTLIRIG
                     DIIQSSTNTNPIIMGIILGGIITVVGTAPLSSMALTALLGLTGVPMAIGAMAAFSSAF
                     MNGTLFHRLKLGDRKSTIAVSIEPLSQADIVSANPIPIYITNFFGGAIAGLIIAMSGL
                     INDATGTATPIAGFLVMFGFNHPMTIVIYGVVMAIVGALAGYLGSIVFKKYPIVTKQD
                     MINRGAVDA"
     gene            9947..11065
                     /locus_tag="RFE25_000428"
     CDS             9947..11065
                     /locus_tag="RFE25_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDU2815528.1"
                     /translation="MSDSEKEILKRIKDNPFISQRELAEAIGLSRPSVANIISGLIQK
                     EYVMGKAYVLNEDYPIVCIGAANVDRKFYVHKDLVAETSNPVTSTRSIGGVARNIAEN
                     LGRLGETVAFLSASGQDSEWEMIKRLSTPFMNLDHVQQFENASTGSYTALISKEGDMT
                     YGLADMEVFDYITPEFLIKRSHLLKKAKCIIVDLNLGKEALNFLCAYTTKHQIKLVIT
                     TVSSPKMKNMPDSLHAIDWIITNKDETETYLNLKIESTDDLKIAAKRWNDLGVKNVIV
                     TNGVKELIYRSGEEEIIKSVMPSNSVKDVTGAGDSFCAAVVYSWLNGMSTEDILIAGM
                     VNAKKTIETKYTVRQNLDQQQLYHDMEDYKNGKFTKVY"
     gene            11040..11963
                     /locus_tag="RFE25_000429"
     CDS             11040..11963
                     /locus_tag="RFE25_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HDU2815529.1"
                     /translation="MANLQKYIEYSREVQQARENNQPIVALESTIISHGMPYPQNVEM
                     ATTVEQIIRNNGAIPATIAIIDGKIKIGLESEDLEILATSKDVAKVSRRDLAEVVAMK
                     CVGATTVATTMICAAMAGIQFFVTGGIGGVHKGAEHTMDISADLEELSKTNVTVICAG
                     AKSILDLPKTMEYLETKGVPVIGYQTNELPAFFTRESGVKLTSSVETPERLADIHLTK
                     QQLNLEGGIVVANPIPYEHALSKAYIEAIINEAVVEAENQGIKGKDATPFLLGKIVEK
                     TNGKSLAANIKLVENNAALGAKIAVAVNKLL"
     gene            11974..13194
                     /locus_tag="RFE25_000430"
     CDS             11974..13194
                     /locus_tag="RFE25_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDU2815530.1"
                     /translation="MNILFAITGIAFALFVAFLFSFDRKNIDFKKTFIMIFIQVLIVL
                     FMMNTTIGLTILTALGSFFEGLINVSKAGINFVFGDIQNKNGFTFFLNVLLPLVFISV
                     LIGIFNYIKVLPFIIKYVGIAINKITRMGRLESYFAISTAMFGQPEVYLTIKDIIPRL
                     SRAKLYTIATSGMSAVSMAMLGSYMQMIEPKFVVTAVMLNIFSALIIASVINPYKSDD
                     SDVEIDNLTKSTETKSVNGKTGKPKKVAFFQMIGDSAMDGFKIAVVVAVMLLAFISLM
                     EAINIMFGSVGLNFKQLIGYVFAPIAFLMGIPWSEAVPAGSLMATKLITNEFVAMLDF
                     KNVLGDVSARTQGIISVYLVSFANFGTVGIIVGSIKGISDKQGEKVSSFAMRLLLGST
                     LASIISGSIIGLVL"
     gene            complement(13299..14831)
                     /locus_tag="RFE25_000431"
     CDS             complement(13299..14831)
                     /locus_tag="RFE25_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDU2815531.1"
                     /translation="MKEVGFGTLNWVAVIIYLLAMLFIGVYFTKRASQSTNSFFTASG
                     RLPSWVVGFSIYATTLSAITFMSTPEKAFLTDWSYIAGNIAIVAIIPLLIYFYVPFFK
                     KLKVTSAYEYLEARFGPSIRVIGSLLFVVYHLGRVAIVIYLPTLAITSVSDMNPYIVA
                     SLVGLLCILYTFLGGFEGVVWSDFIQGVILLGGALVIIILGVMNIKGGFGTVFADAIE
                     HKKLISADNWKLNTAAAAIPIIFLGNIFNNLYQYTASQDVVQRYQASDSLKETNKSLW
                     TNGILALISAPLFYGMGTMLYSFYTHEAVLPKGFNTSSVVPYFILTEMPPFVAGLLIA
                     AIFAAAQSTISSSLNSISACISIDIKQRFFGKDSERHEVNFARFIIIIAGIFGFGMSL
                     YLIASNSNDLWDLFLFVTGLFGVPLAGVFAVGIFTKRTNTFGVICGLILGIIFAYVYN
                     GAGKGNSPFYVSTISFTVAFVFAYILSFIVPSKHKKDITGLTIFEKDKPSTYISKTAT
                     NK"
     gene            complement(14871..15752)
                     /locus_tag="RFE25_000432"
     CDS             complement(14871..15752)
                     /locus_tag="RFE25_000432"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDU2815532.1"
                     /translation="MNKDLKGLYAALLVPFDENGQVNEQGLKQIAQNAIETEELDGLY
                     VNGSSGENFLLNTEQKKQVFKVAKEAVGDKVKLIAQVGSLDLNEAIELGKYATELGYD
                     ALSAVTPFYYPFTFEEIRDYYFDIIEATQNNMIIYAIPDLTGVNISIEQFSELFNHEK
                     IVGVKYTAPNFFLLERIRKAFPDKLILSGFDEMLVQATISGVDGAIGSTYNVNGRRAR
                     KIFDLARQGQIQEAYQLQHDSNDIIETVLSMGIYPTLKEILRHRDIDAGLPKRPFKPF
                     NEAHRQTLDQLIAKYDL"
     gene            15910..16770
                     /locus_tag="RFE25_000433"
     CDS             15910..16770
                     /locus_tag="RFE25_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDU2815533.1"
                     /translation="MYYIAIDIGGTQIKSAVIDKQLNMFDYQQISTPDNKSELITDKV
                     YEIVTGYMKQYQLIQPVIGISSAGVVDEQKGEIGYAGPTIPNYKGTNFKRLLKSLSPY
                     VKVKNDVNAALLGELKLHQYQAERIFCMTLGTGIGGAYKNNQGHIDNGELHKANEVGY
                     LLYRPTENTTFEQRAATSALKKRMIDGGFTRSTHVPVLFEAAEEGDDIAKQILNEWAE
                     DVAEGIAQIQVMYDPGLILIGGGISEQGDNLIKYIEPKVAHYLPKDYVYAPIQTTKSK
                     NDAALYGCLQ"
     gene            complement(17047..17847)
                     /locus_tag="RFE25_000434"
     CDS             complement(17047..17847)
                     /locus_tag="RFE25_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDU2815534.1"
                     /translation="MKFENRVQRYQHLFTKTDKRIVNYIRQNGYSDAFSTINSLAHAI
                     GTSPATMTRFSHKLDYENFQDLKFNIQQEMTETVIENSPIIQRIHKYHQQIIQQTGEF
                     IDNDIIQTFIDKLQSSRHILFAGLGSSGLSATEFYYRMIRMGLKGNVTTDSHLMKISA
                     SLLSHSDMFIAMSNSGNTSELISAAEVAKSHGAYVVAITNFEGSKLTDCADLVLLTTD
                     QSRNTDHQFINTQIATLFLINIVSYHLLENTNLSQTYQHTKSIILDNK"
     gene            17987..18655
                     /locus_tag="RFE25_000435"
     CDS             17987..18655
                     /locus_tag="RFE25_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDU2815535.1"
                     /translation="MLPHGLIVSCQALADEPLHSSFIMSKMALAAYEGGAVGIRANTK
                     EDILAIKETVDLPVIGIVKRDYDHSDVFITATSKEVDELIESQCEVIALDATLQQRPK
                     ETLDELVSYIRTHAPNVEIMADIATVEEAKNAARLGFDYIGTTLHGYTSYTQGQLLYQ
                     NDFQFLKDVLQSVDAKVIAEGNVITPDMYKRVMDLGVHCSVVGGAITRPKEITKRFVQ
                     VMED"
     gene            complement(18786..20099)
                     /locus_tag="RFE25_000436"
     CDS             complement(18786..20099)
                     /locus_tag="RFE25_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiH family protein"
                     /protein_id="HDU2815536.1"
                     /translation="MNQYHSNAQQPSAWRFFVYSLVGILCFFIPFTINGNNTIFVDHV
                     HLAIRSIIGPLMPYVALIMILIGTALPIVRRTFMTSITNLVITLFKVAGAMIGIMYVF
                     KIGPSILFKANYGPFLFEKLMMPLSILIPVGAIALSLLVGYGLLEFVGVYMEPIMRPI
                     FKTPGKSAVDAVASFVGSYSLGLLITNRVYKQGMYNKREATIIATGFSTVSATFMIIV
                     AKTLGLMPHWNLYFWITLVITFVVTAITAWLPPITNESTEYYNGQEGEQEVAIEGSRL
                     KTAYAEAMKQNALTPSLVKNVWDNFKDGLEMTVGILPSILSIGFLGLIVANYTPFIDW
                     LGYIFYPFIYIFPIADQAVLAKASAISIVEMFLPSLLVTKAAMSTKFVVGVVSVSAII
                     FFSALVPCILATEIKIPVWKLIIIWFLRVALSLLITIPVALLIFG"
     gene            20517..22592
                     /gene="lip2"
                     /locus_tag="RFE25_000437"
     CDS             20517..22592
                     /gene="lip2"
                     /locus_tag="RFE25_000437"
                     /EC_number="3.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK domain-containing triacylglycerol lipase
                     Lip2/Geh"
                     /protein_id="HDU2815537.1"
                     /translation="MLRGQEERKYSIRKYSIGVVSVLAATMFVVSSHEAQASEKTPTS
                     NAAAQKETLNQPGEQGNAITSHQMQSGKQLDDMHKENGKSGTVTEGKDTLQSSKHQST
                     QNSKTIRTQNDNQVKQDSERQGSKQSHQNNATNNTERQNDQVQNTHHAERNGSQSTTS
                     QSNDVDKSQPSIPAQKVLPNHDKAAPTSTTPPSNDKTAPKSTKAQDATTDKHPNQQDT
                     HQPAHQIIDAKQDDTVRQSEQKPQVGDLSKHIDGQNSPEKPTDKNTDNKQLIKDALQA
                     PKTRSTTNAAADAKKVRPLKANQVQPLNKYPVVFVHGFLGLVGDNAPALYPNYWGGNK
                     FKVIEELRKQGYNVHQASVSAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGK
                     TYKGIMPNWEPGKKVHLVGHSMGGQTIRLMEEFLRNGNKEEIAYHKAHGGEISPLFTG
                     GHNNMVASITTLATPHNGSQAADKFGNTEAVRKIMFALNRFMGNKYSNIDLGLTQWGF
                     KQLPNESYIDYIKRVSKSKIWTSDDNAAYDLTLDGSAKLNNMTSMNPNITYTTYTGVS
                     SHTGPLGYENPDLGTFFLMDTTSRIIGHDAREEWRKNDGVVPVISSLHPSNQPFINVT
                     NDEPATRRGIWQVKPIIQGWDHVDFIGVDFLDFKRKGAELANFYTGIINDLLRVEATE
                     SKGTQLKAS"
     gene            complement(22834..23661)
                     /locus_tag="RFE25_000438"
     CDS             complement(22834..23661)
                     /locus_tag="RFE25_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2815538.1"
                     /translation="MTEIKYKVITKDAFALPYTIIKAKNQPTKGVIVYIHGGGLMFGK
                     ANDLSPQYIDILTEHYDLIQLSYRLLPEVSLDCIIEDVYASFDAIQSQYSNCPIFTFG
                     RSSGAYLSLLIARDRDIDGVIDFYGYSRINTEPFKTTNSYYAKIAQSINETMIAQLTS
                     PTPVVQDQIAQRFLIYVYARGTGKWINMINIADYTDSKYNIAPDELKTLPPVFIAHCN
                     GDYDVPVEESEHIMNHVPHSTFERVNKNEHDFDRRPNDEAITIYRKVVDFLNAITMV"
     gene            complement(23734..24933)
                     /locus_tag="RFE25_000439"
     CDS             complement(23734..24933)
                     /locus_tag="RFE25_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDU2815539.1"
                     /translation="MYRYKPLLQSIHLPNGIKISNRFVLSPMTVNASTKEGYITKADL
                     AYAARRSNSAGMQVTGAAYIEPYGKLFEYGFNIDHDACIPGLTNMASTMKQHGSLAII
                     QLAHAGRFSNQAILNFGKVYGPSPMTLHSPIEHVVIAMSHEKINSIIQQYRDATLRAI
                     KAGFDGVEISIAQRLLIQTFFSTFSNRRTDHYGADSLKNRARLCLEVMRAVQEVIDKE
                     APDNFILGFRATPEETRGSDLGYTIDEFNQLIDWVMDVSNIQYLAIASWGRHIYQNTS
                     RTPGDHFGRPVNQIVYEHLAGRIPLIASGGINSPESALDALQHADMVGMSSPFVTEPD
                     FVHKLAEQRPHDINLEFSMADLEDLAIPHAAFKDIVKMMDYGEGLKKHTRDALRQLEQ
                     NYHDSSS"
     gene            25029..25121
                     /locus_tag="RFE25_000440"
     CDS             25029..25121
                     /locus_tag="RFE25_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815540.1"
                     /translation="MENIFKIELMNGICRSENMNMKKKNKGEKI"
     gene            25235..26236
                     /locus_tag="RFE25_000441"
     CDS             25235..26236
                     /locus_tag="RFE25_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDU2815541.1"
                     /translation="MVKLSVLDYALIDEGKDAQKALQDSVTLAKLADRLGFKRIWFTE
                     HHNVPAFACSSPELLMMHTLAQTNHIRVGSGGVMLPHYRPYKIAEHFRMMAALYPNRI
                     DLGIGNNPGTTMVKQALDGINPTYDSYDESISLLRDYLTIKDKPSAHTLGVQPHIDHF
                     PEMWLLSSSATSAKIAAELGIGLSVGTFLLPDINAIHAAKDNIDIYKKHFQASTIKMD
                     AKVMASVFVIVADNEAEVAALQHALDVWLLGKLQFAEFEHFPSVDTAQKYKLNDRDKE
                     MIQVHQARIIAGTQEQVKAQLDDFIATFEVDEVLVAPLIPGIEQRCKTLKLLAEIYL"
     gene            26270..26602
                     /locus_tag="RFE25_000442"
     CDS             26270..26602
                     /locus_tag="RFE25_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HDU2815542.1"
                     /translation="MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVK
                     VDDEIVSIEASKTVIDVQTPLSGTIIERNTKAEEEPTILNSEKPEENWLFKLDDVDKE
                     AFLALPEA"
     gene            26603..27403
                     /locus_tag="RFE25_000443"
     CDS             26603..27403
                     /locus_tag="RFE25_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDU2815543.1"
                     /translation="METLKSNKARLEYLINDMRRERNDNDVLVMPSSFEDLWELYRGL
                     ANVRPALPVSDEYLAVQDAMLSDLNHQHVTDLKDLKPIKGDNIFVWQGDITTLKIDAI
                     VNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEIIRQQGRNEGVGKAKKTRGYN
                     LPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQHSLNHVAFCCISTGVFAF
                     PQDEAAEIAVRTVESYLKETNSTLKVVFNVFTDKDLQLYKEALNRDAE"
     gene            27393..28337
                     /locus_tag="RFE25_000444"
     CDS             27393..28337
                     /locus_tag="RFE25_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HDU2815544.1"
                     /translation="MQSSKWNAMSLLMDEKTKQAEVLRTAIDEADAIVIGIGAGMSAS
                     DGFTYVGERFTENFPDFIEKYRFFDMLQASLHPYGSWQEYWAFESRFITLNYLDQPVG
                     QSYLALKSLVEGKQYHIITTNADNAFDAAEYDMTHVFHIQGEYILQQCSQHCHAQTYR
                     NDDLIRKMVVAQQDMLIPWEMIPRCPKCDAPMEVNKRKAEVGMVEDAEFHAQLQRYNA
                     FLEQHQDDKVLYLEIGIGYTTPQFVKHPFQRMTRKNENAIYMTMNKKAYRIPNSIQER
                     TIHLTEDISTLITTALRNDSTTQNNNIGETEDVLNRTD"
     gene            28315..29337
                     /locus_tag="RFE25_000445"
     CDS             28315..29337
                     /locus_tag="RFE25_000445"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDU2815545.1"
                     /translation="MYLIEPIRNGEYITDGAIALAMQVYVNQHIFLDEDILFPYYCDP
                     KVEIGRFQNTAIEVNQDYIDKHSIQVVRRDTGGGAVYVDKGAVNMCCILEQDTSIYGD
                     FQRFYQPAIKALHTLGATDVIQSGRNDLTLNGKKVSGAAMTLMNNRIYGGYSLLLDVN
                     YEAMDKVLKPNRKKIASKGIKSVRARVGHLREALDEKYRDITIEEFKNLMVTQILGID
                     DIKEAKRYELTDADWEAIDELADKKYKNWDWNYGKSPKYEYNRSERLSSGTVDITISV
                     EQNRIADCRIYGDFFGQGDIKDVEEALQGTKMTREDLMHQLKQLDIVYYFGNVTVESL
                     VEMILS"
     gene            29653..30678
                     /locus_tag="RFE25_000446"
     CDS             29653..30678
                     /locus_tag="RFE25_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde reductase"
                     /protein_id="HDU2815546.1"
                     /translation="MNNKVLVTGGTGFVGMRIISRLLEQGYEVQTTIRDLSKADKVIK
                     TMQDNGISTERLMFVEADLSQDEHWDEAMKDCKYVLSVASPVFFGKTDDAEVMAKPAI
                     EGIQRILRAAEHAGVKRVVMTANFGAVGFSNKDKNSITNESHWTNEDEPGLSVYEKSK
                     LLAEKAAWDFVENENTIVEFATINPVAIFGPSLDAHVSGSFHLLENLLNGSMKRVPQI
                     PLNVVDVRDVAELHILAMTNEQANGKRFIATADGQINLLEIAKLIKEKRPEIAQKVST
                     KKLPDFILSLGAKFNHQAKEGKLLLDMNRNVSNERAKTLLGWEPIATQEEAILAAIDS
                     MAKFHLI"
     gene            complement(30772..32118)
                     /locus_tag="RFE25_000447"
     CDS             complement(30772..32118)
                     /locus_tag="RFE25_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDU2815547.1"
                     /translation="MQAILNFIVDILSQPAILVALIAFIGLIVQKKPAATITSGTIKT
                     ILGFLILSAGADVVVRSLEPFGKIFQHAFGVQDIVPNNEAIVSLALKDFGTTAALIMV
                     CGMIVNILIARFTNLKYIFLTGHHTFYMAAFLAIILTVSHIKGWLTIVIGALVLGLIM
                     AVLPALLQPTMRKITGNDQVALGHFGSISYFAAGAVGQLFKGKSKSTEEIKFPKGLSF
                     LRESTISISITMALLYFIACLFAGVSYVHESISDGQNFIVFSLIQGVTFAAGVFIILT
                     GVRLILAEIVPAFKGISEKLVPNSKPALDCPIVFPYAQNAVLIGFFVSFITGVIGMFI
                     LFLFGGVVILPGVVAHFFLGATAAVFGNARGGIKGAVAGAALNGILITFLPLLFLPFL
                     GELGGAATTFSDTDFLTVGIVFGNAVKYMGLFGAILFIIIVGATAILLKGRQKPQQ"
     gene            complement(32133..32417)
                     /locus_tag="RFE25_000448"
     CDS             complement(32133..32417)
                     /locus_tag="RFE25_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDU2815548.1"
                     /translation="MKILVVCGHGLGSSFMVEMNAQEALRQLNAPSDIEVEHSDIMTA
                     SPEMADLFICGRDLAENAERLGDVLVLDNILDKAELQQKLSEKLQQLNMI"
     gene            complement(32419..32862)
                     /locus_tag="RFE25_000449"
     CDS             complement(32419..32862)
                     /locus_tag="RFE25_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDU2815549.1"
                     /translation="MSLDILSTTRIIVKEQVNDWTEAITIASQPLLQEQIIEQGYVQA
                     MIDSVNELGPYIVIAPEIAIAHARPNNDVHQVGLSLLKLNQHVAFCDEDHYASLIFVL
                     SAIDNHSHLSVLQNLATVLGDNQTVQQLLTAKNAQDIKNILKEHD"
     gene            complement(32867..34822)
                     /locus_tag="RFE25_000450"
     CDS             complement(32867..34822)
                     /locus_tag="RFE25_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDU2815550.1"
                     /translation="MLSYRQIEILYLLIHEQTFIPINTIANQLGVSPRTIQYDIAYIE
                     QYAETYHYQVSRNKAAGIKVTTAHATLLNELEHNLTNQIHFSKDERLTHIALKLFETT
                     DPVSTKQLAQDVNVSRRTIADDIKMIQAQLDQYHLKLNYVHNKGFNVIGEEDHYRKAY
                     AHFIHQYMKQAAPFIEADIFNSESIALVRRAIIKTLNSENYHLVQSAIDGLIYHILIA
                     IQRLNENFSFDIPINEIDKWRHTNQYAIASKMIENLERSCNVTFPESEIIFITLHLLG
                     SKMTEHTASSITFEYHDLSQNIHELITCVSQELGIDMSKDNKLHTSLITHIKPAIHRI
                     KYDMLQPNPLRQEVMRRYPQIIEAVSKHISPIEQDAAIRFNEDELTYITIHFASSIER
                     VATHKQSMIKVVLLCGSGIGTSQLLKSKLNHLYPEFHIWDAYSIYQLEESRLLQDNID
                     YVISTVPCEISAVPVIHVDPFINQQSRQKLNQIINDSREQRVMKMATDGKSLADLLPE
                     HRIIINEQPLSIESAIAVAVQPLINDGIVYSNYTAAILKQFEQFGSYMVISPHIALIH
                     AGTDYVQNGVGFALTYFTEGIIFGSKANDPVHLVITLATDHPNAHLKALGQLSECLSN
                     DLYRQDFLDGNIFKIKQHIALTMTKEV"
     gene            35034..35453
                     /gene="mepR"
                     /locus_tag="RFE25_000451"
     CDS             35034..35453
                     /gene="mepR"
                     /locus_tag="RFE25_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor MepR"
                     /protein_id="HDU2815551.1"
                     /translation="MEFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQ
                     QDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVE
                     AFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ"
     gene            35560..36915
                     /gene="mepA"
                     /locus_tag="RFE25_000452"
     CDS             35560..36915
                     /gene="mepA"
                     /locus_tag="RFE25_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498905.1"
                     /note="MepA (multidrug export protein A), as described
                     originally in Staphylococcus aureus, is a MATE transporter
                     shown to be over-expressed after culturing in the presence
                     of tigecycline, owing to mutation of its repressor MepR,
                     and then to be one of several factors contributing to
                     elevated tigecycline resistance; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MepA"
                     /protein_id="HDU2815552.1"
                     /translation="MKDEQLYYFEKSPVFKAMMHFSLPMMIGTLLSVIYGILNIYFIG
                     FLEDSHMISAISLTLPVFAILMGLGNLFGVGAGTYISRLLGAKDYSKSKFVSSFSIYG
                     GIALGLIVILVTLPFSDQIAAILGARGETLALTSNYLKVMFLSAPFVILFFILEQFAR
                     AIGAPMISMIGMLASVGLNIILDPILIFGFDLNVVGAALGTAISNVAAALFFIIYFMK
                     NSDVVSVNIKLAKPNKEMLSEIFKIGIPAFLMSILMGFTGLVLNLFLAHYGNFAIASY
                     GISFRLVQFPELIIMGLCEGVVPLIAYNFMANKGRMKDVIKAVIMSIGVIFVVCMIAV
                     FTIGHHMVGLFTTDQAIVEMATFILKVTMASLLLNGIGFLFTGMLQATGQGRGATIMA
                     ILQGAIIIPVLFIMNALFGLTGVIWSLLIAESLCALAAMLIVYLLRDRLTVDTSELIE
                     G"
     gene            37019..37459
                     /locus_tag="RFE25_000453"
     CDS             37019..37459
                     /locus_tag="RFE25_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MepB family protein"
                     /protein_id="HDU2815553.1"
                     /translation="MYKSKILLKYIFSEESEVKDLTEEKYNQDYEALTFSFKEETYQS
                     RLAKKTPTKAGYFVTCWTKDENNCNQPYSKEAFADYLMIIVIDEELSGYFLFPRELLV
                     EKGILTTFEHKGKMAFRVYPKWCNQLNKTAGQTQKWQCKYFFEY"
     gene            complement(37542..38900)
                     /gene="glpT"
                     /locus_tag="RFE25_000454"
     CDS             complement(37542..38900)
                     /gene="glpT"
                     /locus_tag="RFE25_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HDU2815554.1"
                     /translation="MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLR
                     KNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKFFMGTVSDRSNARIFLVLGLALT
                     AIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
                     NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDT
                     PQSQGLPPIEIYKNDFATSDKKTLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVR
                     YGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYISDKLFKGRRGPAGFF
                     FMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAA
                     GLTGLFGYLFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETV
                     HH"
     gene            39212..40138
                     /locus_tag="RFE25_000455"
     CDS             39212..40138
                     /locus_tag="RFE25_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDU2815555.1"
                     /translation="MNIVGHHHISMYTKDAKRNKDFYTNVLGLRLVEKSVNQDNPSMY
                     HLFYGDEVGTAGTILSFFEIPHAGHKQPGTETIYRFSLLVPNQAALHYFEKRLDNNGI
                     TSERLYYLGQEGVVFKDEDDLEIILLVNDSFEVPHQWQHNAYSEIPQAYQILGIGPVE
                     LRVRNAARTVEFLENVLGYRKRDNKSFDVLTLAPQGLYSDFVVIEQQGQRERPGRGYI
                     HHIAINTPQMSDLDAIYKKLQQQTQSNSGIIDRYFFKSLYYRHNSIMYEFATEAPGFT
                     IDTPLEQLGSQLNLPDFLEAEREQIESKLHEI"
     gene            40152..41213
                     /locus_tag="RFE25_000456"
     CDS             40152..41213
                     /locus_tag="RFE25_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDU2815556.1"
                     /translation="MAKLEMNKNTPLEFGLYSLGDHLLNPFKGEKVSYEQRINEIIEA
                     SKLADETGIDVFAVGESHQEHFTTQAHTVVLGAIAQATKHIKVSSSSTIISATDPVRV
                     FEDFATLDLISHGRAEIVAGRASRTGIFDLFGYDLKDYDELFEEKLGLLLELNKTERI
                     TWSGKYRPELRNMKIFPRPIDNILPIWRAVGGPPASAIKAGKQGVPMMITTLGGPAMN
                     FKGSIDAYRQAATEAGFDASHKSLPVSTASLFYTAETTQDAMREFYPHLNTGMSFIRG
                     VGYPKQQFANSSDYREALMVGSPQQIIEKILYQHELYGHQRFMAQLDFGGVPFENVMK
                     NIELIGNEIIPAIKKHLSK"
     gene            41227..41793
                     /locus_tag="RFE25_000457"
     CDS             41227..41793
                     /locus_tag="RFE25_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDU2815557.1"
                     /translation="MNIVLLSGSTVGSKTRIAMDDLKNELEVINEGHQIELMDLRELE
                     LEFSVGKNYLDTTGDVYKLTTSLMQADVIFIGFPIFQASIPGALKNVFDLLPVNAFRD
                     KVIGLVATAGSSKHYLIPEMHLKPILSYMKAHTMQTYVFIEEKDFSNQQIVNDDVVFR
                     LKALAQFTMRTAKVQQQVFEEENNQYDF"
     gene            complement(41852..42847)
                     /locus_tag="RFE25_000458"
     CDS             complement(41852..42847)
                     /locus_tag="RFE25_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HDU2815558.1"
                     /translation="MASLKNKHFMIGLSLTFIVALFSFLAAKLPILDKVGALTIAILI
                     AILYRHFRGYPEQYSSGITFSSKYLLRFAIILYGLKLNIFDIIGQGSKLLAIDVGVVI
                     FSIVMMLFVNKLLHGDKNIALLLGVGTGVCGAAAIAAVAPIFKSREKDTAISIGIIAL
                     IGTIFSLIYTAIYAIFSMTTNVYGAWSGVSLHEIAHVVLAGGFGGSDALKIALLGKLG
                     RVFLLIPLTIVLILIMRFRSSESSSKGRISIPYFLIGFVIMALVNTYVTIPSVLLNIL
                     NTISTICLLMAMVALGLNVAFKDLKNRALKPLMTIIITSICLSSLAFIVVHWLYS"
     gene            43212..43757
                     /locus_tag="RFE25_000459"
     CDS             43212..43757
                     /locus_tag="RFE25_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2815559.1"
                     /translation="MFGMKVNEQITLKILEAHDTEALFNLVNRSRNSLREWLPWVDAT
                     EQPSDTRAFIKRGLLQFADGNGFQCGIWYEGTLVGVIGLHEINHMHRKTSLGYYLDKQ
                     FEGHGIMTQAVEALIKYCFEELDLNRIEISAAVNNEKSRAIPERLGFTREGMLRDNEL
                     LNGIYSSSYIYSLLKSEYDQK"
     gene            44024..44878
                     /locus_tag="RFE25_000460"
     CDS             44024..44878
                     /locus_tag="RFE25_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815560.1"
                     /translation="MKKLTTLLLASTLLIAACGNDDSKKDDSKTSKKDDGVKAELKQA
                     TKAYDKYTDEQLNEFLKGTEKFVKAIENNDMAQAKALYPKVRMYYERSEPVAEAFGDL
                     DPKIDARLADMKEEKKEKEWSGYHKIEKALYEDKKIDDVTKKDAQQLLKDAKELHAKA
                     DTLDITPKLMLQGSVDLLNEVATSKITGEEEIYSHTDLYDFKANVEGAQKIYDLFKPI
                     LEKKDKKLSDDIQMNFDKVNQLLDKYKDNNGGYESFEKVSKKDRKAFADAVNALGEPL
                     SKMAVITE"
     gene            44875..46104
                     /gene="efeB"
                     /locus_tag="RFE25_000461"
     CDS             44875..46104
                     /gene="efeB"
                     /locus_tag="RFE25_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HDU2815561.1"
                     /translation="MTNYEQVNDSTQFSRRTFLKMLGIGGAGVAIGASGVGSMWSFKS
                     MFNTPEDPEKDAYEFYGKVQPGITTPTQKTCNFVALDLKSKDRDAIKAMFKKWTVMAD
                     RMMDGDTVGKTSNNPLMPPVDTGESIGLGASKLTITFGISKSLMKKIGLSSKIPDAFK
                     DLPHFPNDQLIDDYSDGDIMIQACSNDSQVSFHAVHNLVRPFRDIVKVRWAQSGFISA
                     KGKETPRNLMAFKDGTINPRKSNQLKDYVFIDDGWAKHGTYCVVRRIQIHIETWDRTA
                     LEEQEATFGRKRHSGAPLTGGKEFDEIDLKAKDSHGEYIIDKDAHTRLAKEANTSILR
                     RAFNYVDGTDDRTGNFETGLLFIAFQKATKQFIDIQNNLGSNDKLNEYITHRGSASFL
                     VLPGVSKGGYLGETLFD"
     gene            46085..47797
                     /locus_tag="RFE25_000462"
     CDS             46085..47797
                     /locus_tag="RFE25_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family iron permease"
                     /protein_id="HDU2815562.1"
                     /translation="MKHYLTKFVAMLITAAMVCSFGLLKSQAAEQQSISDVYSVITDA
                     KSALSNNSISNDNKQKAIEQVVSAVKKLSLEDNSEGNAVKSDVRKLEDAKANDNQKDT
                     LSQLTKSLIAYEEKLASKDAGSKIKLLQQQVDAKDAAMTKAIKDKNKAELESLNNSLN
                     QIWTSNETVIRNYDANQYGQIEVALLQLRIAIHKSPLDTAKVSHAWTTFKSNIDHVDK
                     KSDTSANDQYHVSQLNDALEKAIKAIDDNQLSDADAALTHFIEIWPYVEGQIQTKDGA
                     LYTKIEDKIPYYQSVLDEHNKSHVKDGLVDINNQIKEVVGHSYSFVDVMIIFLREGLE
                     VLLIVMTLTTMTRKVKDNKGTASVIGGAIAGLVLSIILAITFVETLGNSGILRESMEA
                     GLGIVAVILMFIVGVWMHKRSNAKRWNDMIKNMYANAISNGNLVLLATIGLISVLREG
                     VEVIIFYMGMIGELATKDFIIGIALAIVILIVFAVLFRFIVRLIPIFYIFRVLSIFIF
                     IMGFKMLGVSIQKLQLLGAMPRHVIEGFPTINWLGFYPSYEPLIAQAAYIMVVAILIF
                     KFKK"
     gene            complement(48038..48700)
                     /gene="tatC"
                     /locus_tag="RFE25_000463"
     CDS             complement(48038..48700)
                     /gene="tatC"
                     /locus_tag="RFE25_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006191819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HDU2815563.1"
                     /translation="MLLSFVVTVIVVYVSSFWWMTPFITYITRAHVSLHAFSFTEMIQ
                     IYVMIIFFIAFCFISPVMFYQLWAFIAPGLHNNERQFIYKYSFFSVLLFCAGVAFAFY
                     VGFPIIIQFALKLSLTLNISPVIGFKAYLVELIRWLFTFGILFQLPILFIGLAKFGLI
                     DITSLKHYRKYIYFACFVLASIIAPPDLTLNILLTLPLILLFEFSMFIVKFTCRGKPP
                     TH"
     gene            complement(48756..48980)
                     /locus_tag="RFE25_000464"
     CDS             complement(48756..48980)
                     /locus_tag="RFE25_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /protein_id="HDU2815564.1"
                     /translation="MIIMITNTFILGITGPTSLVVISIIALIIFGPKKLPQFGRAIGS
                     TLKEFKSATEDLDKESHDTPSKESKQQREQ"
     gene            complement(49080..49469)
                     /locus_tag="RFE25_000465"
     CDS             complement(49080..49469)
                     /locus_tag="RFE25_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HDU2815565.1"
                     /translation="MAFTLSAIQQAHQQFTGVDFPKLFKAFKDMGMTYNIVNIQDGTA
                     TYVHQSEDDIVTSSVKSNHPVAQKSNKTIVQDVLTRHQQGQTDFETFCDEMAEAGIYK
                     WHIDIQAGTCTYIDLKEQAIISELIPQ"
     gene            49709..49912
                     /locus_tag="RFE25_000466"
     CDS             49709..49912
                     /locus_tag="RFE25_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2815566.1"
                     /translation="MRNRLKELRARDGLNQTQLAKLAGVSRQTISLIERNNFMPSVLT
                     AIKIARIFNETVETVFIIEEDEA"
     gene            49909..50622
                     /locus_tag="RFE25_000467"
     CDS             49909..50622
                     /locus_tag="RFE25_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HDU2815567.1"
                     /translation="MKILRYIGYLLLGGIVGGIIGGILGNFDGLGIENLTFATYNNVV
                     VISIVATMIIILVEAIVLMNQRRALKYKRLVDEEVDIDATDQYELLANRYVLNGSILS
                     VIQTIIAFVVLLIFVVGQAEANAMLFFLIPFFASAIFNTQFTLFNRKFDDRMPKIADK
                     NYTEKRLEILDEGERHIELIALFKTYAINLSILILAIIFIGSYSIATGINQSFSLLLI
                     IAIFIYNAFSYLLKRRRFY"
     gene            50647..51489
                     /locus_tag="RFE25_000468"
     CDS             50647..51489
                     /locus_tag="RFE25_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815568.1"
                     /translation="MTTLLNVDRVNKQYKDSDFKLQDASLTISTNETVGLIGKNGSGK
                     STLINILVGNRHKDNGSIAFFGEEHAADDVEYKEHIGVVFDDLRVPNKLTIKDIDKVF
                     QSIYTTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIALSHDVKLLILDEATA
                     GMDVSGREEVMELLEDFVAQGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDIL
                     LAQYGIVTTGDKDVEIPKHLIIASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIM
                     RGEV"
     gene            51489..52118
                     /locus_tag="RFE25_000469"
     CDS             51489..52118
                     /locus_tag="RFE25_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDU2815569.1"
                     /translation="MKGMFLSSFYATRKQTYIYFIVAIIAAGYFAVFNPLMSSAMAGV
                     MLITPITDNIKHEKDSRWMYYVSTLPVKRSDYIKSYFAFYLILFGASLMIGLVVTTIV
                     TQSVMIGIMSGLMSFGIIGAYSIIFPLTFKFGAENSNVIMIVASILLLFSFVVFFFIY
                     GMVSGASALEFEKISTEGWLVVIVYAVIGIVITSVSYILSIKIFNKQEL"
     gene            complement(52510..53643)
                     /locus_tag="RFE25_000470"
     CDS             complement(52510..53643)
                     /locus_tag="RFE25_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low temperature requirement protein A"
                     /protein_id="HDU2815570.1"
                     /translation="MVNALTPKHLAEKRAGFHELFFDLIFVYAIQKIAHVILTTQNGS
                     ISADLFFKYIVMSLFLWLMWSHQTFFTNRFGQVTFKDVSFMMFNMFIMVFLSNSLYPD
                     FEKTFFPFFLCVAIMYLSIGLQYLLHIRTGLDYGDKRTCQAFASVAFVISFLSFLSLV
                     LPQSIHYIPGFLGVFIAATGLIPFQKYLVLSPVNMMHLVERFSLLTIIIFGEVLVGLA
                     SSSFSIDHFSYIYIFQFMILISLFGVYWIITENYINHKLSSIGFRLSYTHLLINIALG
                     VINAAIVFSNNNKLNDLFEINMMYISVLIFYIGLWLITPYFHNELTNAKYISSSLGIL
                     VVSYIISLIFKGHDQVMIISVSVATFCIMLIYFKNQRLRNKHE"
     gene            54182..55363
                     /locus_tag="RFE25_000471"
     CDS             54182..55363
                     /locus_tag="RFE25_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDU2815571.1"
                     /translation="MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLN
                     PSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSI
                     VTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGIT
                     AENLVEQYGISREEQDTFAVNSQHKAVCAQQNGEFDSEIVPVSIPQRKGEPILVTKDE
                     GVRENVSVEKLSRLRPAFKKDGTVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVL
                     DGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAFAAQLLAVDRELKLP
                     PEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKY
                     K"
     gene            complement(55446..56198)
                     /locus_tag="RFE25_000472"
     CDS             complement(55446..56198)
                     /locus_tag="RFE25_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDU2815572.1"
                     /translation="MTQYPLWQQLNTLKQATWVDLTHTFDPEIPRFSEFEKGEVSTLF
                     TVKDHGFYVQRWNIVTQYGTHIDAPIHFVENKRYLEDIDLKELVLPLIVLDFSTEVAN
                     NNDFIVTRAHIEAWEKEHGTIEPGTFVALRTDWSKRWPNIEKFENKDANGQQHAPGWG
                     LDALKYLIEERRVEAVGHETFDTDASVDVVKNGDLVGERYILGQDKYQVELLTNLDQL
                     PTRGAIIYAISPKPKDAPGFPVRAFAIKPSND"
     gene            complement(56241..58469)
                     /gene="metE"
                     /locus_tag="RFE25_000473"
     CDS             complement(56241..58469)
                     /gene="metE"
                     /locus_tag="RFE25_000473"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDU2815573.1"
                     /translation="MTTIKTSNLGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDL
                     HKENLLLQKYYHLDSIPVGDFSLYDHILDTSLLFNIIPERFQGRTIDDDLLFDIARGN
                     KDHVASALIKWFNTNYHYIVPEWDNVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPIT
                     FVKLSKGGHQTFEEKVKTLLPLYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITR
                     EAYDYFEKAGVAKKLVIQTYFERAHLKFLSSLPVGGLGLDFVHDNGYNLKQIEAGDFD
                     KSKTLYAGIIDGRNVWASDIEAKKVLIDKLLAHTNELVIQPSSSLLHVPVSLDDETLD
                     TSVGEGLSFATEKLDELDALRRLLNQNDSVKYDKLKARYERFQNQSFKNLDYDFESVR
                     TSRQSPFAQRIEQQQKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFL
                     KNEIARWIKIQEDIGLDVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKP
                     PIIYGDVKWTAPLTVDETVYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQI
                     ALAINEEVLALEAAGIKVIQVDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDE
                     TQIHTHMCYSQFGQIIHAIHDLDADVISIETSRSHGDLIKDFEDINYDLGIGLGVYDI
                     HSPRIPTKEEITTAINRSLQQIDRSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKR
                     QE"
     gene            complement(58466..60307)
                     /locus_tag="RFE25_000474"
     CDS             complement(58466..60307)
                     /locus_tag="RFE25_000474"
                     /EC_number="1.5.1.20"
                     /EC_number="2.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional homocysteine
                     S-methyltransferase/methylenetetrahydrofolate reductase"
                     /protein_id="HDU2815574.1"
                     /translation="MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVE
                     RIHRSYIEAGADVIQTNTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILG
                     TVGGFRGIKQEDISLQTILYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKK
                     YDIPIIAQLTASNTNYLVNGQAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIEL
                     PEHAFLSCYPNASLLDIENSEFKYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIK
                     FIKESIQTLKPVNDKKVIPIPTKALFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLD
                     TDRFFENIAKLDKANVDAVTLADNSLATVRISNIAAASLIKQYYNIEPLVHITCRDRN
                     LIGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNSKGLTELALRFNQGIN
                     TDGDALKKRTHFNIAGAFNPNVRKLDGAVKRLEKKIESGMSYFITQPVYSKEKIIEIY
                     HATKHLNKPFFIGIMPIASYKNALFLHNEVPGIKMSDEILQQFEAVKDDKAKTRELSL
                     KLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAAYSKSITAHKEAIL"
     gene            complement(60276..61436)
                     /locus_tag="RFE25_000475"
     CDS             complement(60276..61436)
                     /locus_tag="RFE25_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HDU2815575.1"
                     /translation="MTLSKETEVIFDWRRGVEYHSANPPLYDSSTFHQTSLGGDVKYD
                     YARSGNPNRELLEEKLARLEQGKFAFAFASGIAAISAVLLTFKSGDHVILPDDVYGGT
                     FRLTEQILNRFNIEFTTVDTTKLEQIEGAIQSNTKLIYIETPSNPCFKITDIKAVSKI
                     AEKHELLVAVDNTFMTPLGQSPLLLGADIVIHSATKFLSGHSDLIAGAVITNNEAISE
                     ALYLIQNGTGNMLSAQDSWTLAKHLKTFPIRFKQSVENAQKIVSFLIKQDEISEVYYP
                     GLTTAHLEQAKNGGAVIGFRLADESKAQQFVDALTLPLVSVSLGGVETILSHPATMSH
                     AALPEEVRQERGITFGLFRLSVGLEDPDELIADIKYALKEAFNESIPHTIER"
     gene            complement(61433..62536)
                     /locus_tag="RFE25_000476"
     CDS             complement(61433..62536)
                     /locus_tag="RFE25_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDU2815576.1"
                     /translation="MKDTQLAQITLTDDSTGAIANPIHLSTAYKHPKLGQSTGFDYTR
                     TKNPTRSTFETCFAKLEHGIASFATSSGMSAIQLICNLFKPHDEILVSFDLYGGTFRL
                     FEFYEQQYDIKFKYVDFTDYEQVEKEITDKTVALFIEPISNPQMIAIDVKPYYQLCKA
                     KGLLSIIDNTFLTPYLSTPLAEGADIVLHSATKYIGGHNDVLAGVVTVKDESLAQQLF
                     DFHNMTGATLSPIDSYLLLRGLKTLHLRIERAQSNARKLAKKCQSLQAIDEVLYSGQT
                     GMLSLRLNKAYSVAKLLENLDICIFAESLGGTETLVTFPYTQTHVDMPDAEKDKRGID
                     EYLIRLSLGVENYEDIERDIIQALDKAQIGEIV"
     misc_binding    complement(62600..62969)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            63198..64043
                     /locus_tag="RFE25_000477"
     CDS             63198..64043
                     /locus_tag="RFE25_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDU2815577.1"
                     /translation="MSELSKSEDQRITKTKDEQIKQIDISDIKPNPYQPRKTFDENHL
                     NDLADSIKQYGILQPIVLRKTVQGYYIVVGERRFRASKIAGLKYVSAIIKDLTDEDMM
                     ELAVIENLQREDLNAIEEAESYQRLMTDLKITQQEVAKRLSKSRPYIANMLRLLHLPK
                     KIADMVKDGRLTSAHGRTLLAIKDEQQMLRLAKRVVKEKWSVRYLENHVNELKNVSSK
                     SETDKVDITKPKFIKQQERQLREQYGTKVDISIKKSVGKISFEFDSQDDFVRIIEQLN
                     RRYGK"
     gene            64197..65078
                     /locus_tag="RFE25_000478"
     CDS             64197..65078
                     /locus_tag="RFE25_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HDU2815578.1"
                     /translation="MDQVMSIISSLFEPLTKIETYENIATKIAMIVIYIIVALIVIKI
                     LNKMIEQGFKIQNKSKKSNKKRSKTLISLVQNVVKYIVWFIVITTILSKFGISVEGVI
                     ASAGVVGLAVGFGAQTIVKDVITGFFIIFESQFDVGDYVKINNGGTTVAEGTVKSIGL
                     RSTRINTISGELTILPNSSMGEITNYSITNGTAIVKIPVSVDENIDNVEKKLNKLFTS
                     LRSKYYLFVSDPVVIGIDAFEDTRVILRVSAETIPGEGFSGARIIRKEVQKMFLQEGI
                     KTPQPIMTPFNHSENGV"
     gene            65108..65311
                     /locus_tag="RFE25_000479"
     CDS             65108..65311
                     /locus_tag="RFE25_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDU2815579.1"
                     /translation="MASKYGINDIVEMKKQHACGTNRFKIIRMGADIRIKCENCQRSI
                     MIPRQTFDKKLKKIIVSQDDTQR"
     gene            65323..66420
                     /gene="ychF"
                     /locus_tag="RFE25_000480"
     CDS             65323..66420
                     /gene="ychF"
                     /locus_tag="RFE25_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDU2815580.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGALAANYPFATIDPNVGIV
                     EVPDARLLKLEEMVQPKKTLPTTFEFTDIAGIVKGASKGEGLGNKFLSHIREVDAICQ
                     VVRAFDDDNVTHVAGRVDPIDDIEVINMELVLADLESVEKRLPRIEKLARQKDKTAEM
                     EVRILTTIKEALENGKPARSIDFNEEDQKWVNQAQLLTSKKMLYIANVGEDEIGDDDN
                     DKVKAIREYAAQEDSEVIVISAKIEEEIATLDDEDKEMFLEDLGIEEPGLDRLIRTTY
                     ELLGLSTYFTAGVQEVRAWTFKQGMTAPQCAGIIHTDFERGFIRAEVTSYDDYVQYGG
                     ESGAKEAGRQRLEGKEYIMQDGDIVHFRFNV"
     gene            complement(66506..66697)
                     /locus_tag="RFE25_000481"
     CDS             complement(66506..66697)
                     /locus_tag="RFE25_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815581.1"
                     /translation="MNLNIDWSKDFQEFQEILNSGIHPEWLYCAKANLVLEPAYTGEG
                     KQFFSTQDIIYASKIIPFF"
     gene            66941..67237
                     /locus_tag="RFE25_000482"
     CDS             66941..67237
                     /locus_tag="RFE25_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDU2815582.1"
                     /translation="MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWG
                     KRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK"
     gene            67258..67761
                     /gene="ssb"
                     /locus_tag="RFE25_000483"
     CDS             67258..67761
                     /gene="ssb"
                     /locus_tag="RFE25_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDU2815583.1"
                     /translation="MLNRVVLVGRLTKDPEYRTTPSGVSVATFTLAVNRTFTNAQGER
                     EADFINCVVFRRQADNVNNYLSKGSLAGVDGRLQSRNYENQEGRRVFVTEVVCDSVQF
                     LEPKNAQQNGGQRQQNEFQDYGQGFGGQQSGQNNSYNNSSNTKQSDNPFANANGPIDI
                     SDDDLPF"
     gene            67813..68055
                     /gene="rpsR"
                     /locus_tag="RFE25_000484"
     CDS             67813..68055
                     /gene="rpsR"
                     /locus_tag="RFE25_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002484306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDU2815584.1"
                     /translation="MAGGPRRGGRRRKKVCYFTANGITHIDYKDTELLKRFISERGKI
                     LPRRVTGTSAKYQRMLTTAIKRSRHMALLPYVKEEQ"
     gene            complement(68287..>68629)
                     /locus_tag="RFE25_000485"
     CDS             complement(68287..>68629)
                     /locus_tag="RFE25_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001800370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="growth inhibitor PemK"
                     /protein_id="HDU2815585.1"
                     /translation="IKTRFPTEREVINKSKNIVESFNLYNDPKNFSALFNYLLIDVND
                     RKSKVNNLREVINKYKKFDKNTFACTQNVVTISKLRILKINAEDPSGRMKLDFDSMKL
                     VDNEIKNKLIN"
BASE COUNT        23613 a        10349 c        13116 g        21551 t
ORIGIN      
        1 cggatttata tagattgttt aagaagttaa gaaacgcatt taaagaagaa gatttagaac
       61 catggacatc atgtgaattt gactttacaa gcgaaggtaa attaaaagtt tcatttgatt
      121 atattgattg gataaataca gagtttgatc aattaggccg tgaaaattat tatatgtata
      181 aaaaatttgg ggttatacca gaaatggaat acgaaatgga agaagttaaa gaaatcgagc
      241 aatatattaa agagcaagat gaagctgaac tataggggcg ataatatgat tttcgaagaa
      301 aaactaagtc aaatgtacaa tgaaattgca aatgaaatca gtgggatgat accagtagag
      361 tgggaaaaag tatatacaat tgcttatgta gatgatgaag gtggagaagt cgtttttaat
      421 tatactaaac caggtagtga tgaattgaat tattacacat atatccctag agagtataat
      481 gtctctgaaa aagtatttta tgatttgtgg acggatttat atagattgtt taagaagtta
      541 agaaacgcat ttaaagaaga tttagaacca tggacatcat gtgaatttga ttttacaaga
      601 gagggtaatt tgaaagtatc gtttgattat atagattgga ttaaattagg ttttggtcca
      661 tcaggaaagg aaaactacta tatgtataaa aagtttggtg ttttaccaga aacggaatat
      721 gaaatggaag aaattcgaga agtagagaag tatgttaaag accaagagta gcatatatgt
      781 tatagaaggc tgtgcaaaat caccctcgtt ttacatttga ctcaaagaag aaggtaaacg
      841 ataagattat ttgcaactta aaaagtttat tagcttctcg gtatccatac atcatatgta
      901 taaatgagtt taactaatta ataaatcacg atataaattt aaaattgcca ttaattgaaa
      961 aggttattgt agtgtatttt ataaagttga tgcacatcga cttatttttt aaaacttata
     1021 tcaaaaaaat atgagaaaag tatatactat taaaatgttt ttttactata attataaata
     1081 gttaaatatt tggttatgaa ataaatgtgt gggaggcaat ttttagagat acatagcaat
     1141 gtaaagatat caaatagtta ttgcataatt tattatgatg acataatttt cagtagatag
     1201 ttgtaaatta acactgaaat agatgtttat attaagaaga ctttaatatc ataattaatc
     1261 aaaatcttgc gtcaaacatt taaacgaatt ttaagttgat aacaattggt taaacattgt
     1321 tcaaacatca caatgataaa gcatattatc agtattgtag tgtgtggaaa atgacagcca
     1381 tctaaggaga aaaatgatga aaagaatatt ggtagtattt ttaatgttag caattatatt
     1441 ggcaggttgt tctaataaag gtgaaaagta tcaaaaagat attgataaag tgtacaaaga
     1501 acagaatcaa atgaataaaa ttgcctcgaa agtacaaaac actattaaaa cagacattaa
     1561 acaagaagac agtaatacac atgtctataa agatggtaaa gtcattgtta ttggtattca
     1621 attatataaa gatcgtgaaa aaatgtatta tttcgcatat gaaataaaag atggtaaggc
     1681 agagattaat agagaaatag acccaattaa gtatatgaaa gaccataaag cagattatga
     1741 agatgaaaat gtagaagtgg aaaaagatta acgtaggctt tctttaaaac ttttaaccag
     1801 tttcaaaaag taaatgagct ttagcgacaa taatttttaa aataaacacg atataaattt
     1861 aaacatttat atataagaac acaaacgtaa gtttgtaaat aataataaag gagtaagtca
     1921 atggaaaaat cgatcaaaat aatgacaata ataggaattg ttattcaggg tttagcaacg
     1981 gtatttagtt tactattgat ggttttagca gcatcaggtg taatgactac agatgtgtca
     2041 acaacagtta atggtgaggt tgacccagtt gatgcagaaa cagcagcagc aattttcact
     2101 gtattattct tatccctatt catatttgga atcatttcaa ttattttagg tgcaatcggt
     2161 atgtttaaag catctaaaaa caaaaaaatg agtggtatat tgttgattat tggagctgta
     2221 ataagtggta acataattac atttgcttta tggttagtca gtggtattaa actacttact
     2281 aataacaagc ctaaagatga aataagcgac ttatcataaa catcgtatat tgaaatttca
     2341 agatttctta agtaattaaa taaagtgctc tcttagaagt agattttcag tcaataactg
     2401 cttttaaaag agcattttgt atttgataat gctcatagca tcggacaaaa accattgacg
     2461 aacttaaaaa aaacacgtta gacaatgcac ttctaaatat ttaaggcatc gactaacgca
     2521 ttgttcaaat atagttaatt atttttataa aattgatgat gatcattcaa gtaagcatag
     2581 aataaaccta taatgagtcc gcctccaata tagttaccga taaaagccgc agtgatattc
     2641 gaaatagctg gtatgaagtg caatgtatca acttgataaa ttaaaccacc cataaataag
     2701 caactgttgt aaacgacgtg ttcataaccc ataaaggcga atatggtaac accgaacatc
     2761 atgacaaaca tttttgcgag tacatcgtca atttgcatgg caataactaa tgaaatattg
     2821 ataaagaaat tggcgaagat cgctttcatt aatatactta caaaaccagt agacaacgtt
     2881 ttgtgctcaa taactgctga taactgattt aacatatctg gcgtcattac atttgaaaaa
     2941 cgcatgaaac taaataaaat agcagcacct aaaatatttc ctgcaaagca taataaaaat
     3001 attttcaata ctctagtcgg tttaattact ttataataca ggcctacagt aaagtacatg
     3061 aagttactgg ttagtagttc ggagtttgta aataaaatga gtactaacgc aaagctgaat
     3121 gtaatggcgc tagccatatt cactatacct ggtggtaaat ctggttcgtg tgttgcttta
     3181 actgatagca cgaagaccgt aataataccg ataataaatc ctgccatcat cgcgcgtaat
     3241 aaataacgtt ttaaataaac gctttgtaat atatcttttg ttcttattgt ttcgactacg
     3301 ttatttaccc agtcatcccc ataaaaaatc ttatcccatt taatatgttt ctccttcaca
     3361 atgacatcct cgcttttcat ttgttaatca gagtatacta tgaatcgtct tatttgtgaa
     3421 taatttcaca aaattaattt taaaaactaa tatttttgaa taactgatag gattttttgg
     3481 taaatcaatt attttaaaat aatcaataga cagacagtat cgctgaaaat ccatgaattt
     3541 catataaaaa agcctagtaa cgagggggca atcattacta ggcagtgagc atttattaag
     3601 ttgtcgcttg tttcggacga cgtataacta catcgatgat gaaaccgata atagcaaaga
     3661 gcatgaatgg tacaagccaa gctaaatcga tatctgctaa aggtaacatc ataaaccatt
     3721 tcaaaataac accgtgtaat aagttgaaac tatttagtat ttgtaaaatt gaaataatca
     3781 atgtaataac agttgcgagt cgataggccc aactgaatct gaatgtgcta aacatgttag
     3841 caaatgatat cagtacaagt gcaatagaca cgggatatat taatgtcaac aatggtacag
     3901 caatttttaa aatcatttct aaaccaagtg ttgtaaataa gaaccctatg atagagaaaa
     3961 taagtgcgaa tattttataa gaaaacttag gtacgtgttt cttagtaaat gtggcgcaag
     4021 cattgacgag tcctatacat gttgttaaac atgcaagtat cactgtcata ccaaatacta
     4081 tgttgccaaa tgaaccaaat actcgtaatg agttgtacgt caatatatct gtaccatctt
     4141 taaagtttcc tggagctgtt gatgccccaa cgtatgcaag tgcaaagtaa atcattccaa
     4201 gtaatatggc tgcaataaga cctgaaaagc agacatattt taaaattttc atgcgatctg
     4261 tgaggccttt aaacttataa ccattgacaa tgactacgga aaaagctaac gcagcaacaa
     4321 gatccattgt aaaatagcct tccaaacttc ctgaaatgaa aggatgtgtt atatatttat
     4381 ccttaggtgc acttagtgca gattcagggt tgaaaatgac agcaatactt aatagagcga
     4441 ccattaatag taataatggt gttaataatt tacctaaatt atcaacgatt ttcgatggat
     4501 ttaaactaat ccagtaaacg atggcaaaaa agattgctgc gaatataatt aaagtccatt
     4561 ggttatgcac aggtaaaatg tgtcttgtac caatttcgta cgcgacattt gcagcacgtg
     4621 gaataccgta aaatgctccg atagacatgt aaatcacgac agcaaaaata aacccgaacc
     4681 atggatgtat acgattgcct acactttcaa caccttcatc ataaaatgca acaacaataa
     4741 cagtaataaa ggggagtaat atgcctgtaa gggcaaagcc tagcatacca atccacatat
     4801 tttgacccgc tgtatggcca agaatgggcg ggaatattaa atttccggct ccaaaaaata
     4861 gtgaaaataa catgaggccc gaaataataa cttgtttttt caatgtaatt tccttcctaa
     4921 aactagatat tcataataat ttaaaaaatc tgaaaaataa aaacgttctt actttatctt
     4981 taaatgacaa tactatgatt ctattatttt ataaaaaaga ttgcaataat aacgtcttgc
     5041 tattattgga taatgacaat taaagtgtcg tttttatgaa ttaaaatagg tgaaagtaag
     5101 ttggaaatac gttggagcgt tgtgattttt atgagaaatt gtatgagtga ggactgctat
     5161 ttataaaagg taaactatgg atgagtttat ggttgttcca ataggtaaat aagagatagc
     5221 acactgtaca cataatgata cgtggatgag tgaatatgtc tgataggaag gcctagtcac
     5281 tcaaatgaat ttaagtttat tacgtgataa atcacaaatc tctctcatgt gataggtctc
     5341 ccattaaatc atgcttatat gaaatgttca catatttgtt agcttttcaa gaaataatat
     5401 taaatatctt ttcatagtat agcaatatta aataaatgca tttataattt taactgtatt
     5461 ttaaatatta atcatgaggt gataagatga ataaaatttc aaagtatatt gcaatagcat
     5521 cattatcggt agcggttaca gtttcagcac cacaaacgac aaattctaca gcgtttgcca
     5581 aaagttctgc tgaagttcaa caaacgcaac aagcttctat accagcatca caaaaggcga
     5641 atcttggtaa tcaaaatatt atggcagtgg cttggtatca aaattcagct gaagcaaaag
     5701 cattatattt acaaggttat aacagtgcaa agacacagtt agataaagag attaaaaaga
     5761 ataaaggtaa acataagtta gctattgctt tggatttaga tgaaacagtt ttagataatt
     5821 ctccatatca aggctatgca tcaatacata ataaaccttt cccagaaggt tggcatgaat
     5881 gggtacaagc tgctaaagct aaacctgtct atggcgcaaa agaattcttg aaatatgctg
     5941 acaaaaaagg tgtcgatatc tactatattt ctgatagaga taaagaaaaa gatttaaagg
     6001 caacacaaaa gaacttaaaa caacaaggta tccctcaagc taagaagagt catattttac
     6061 taaaaggtaa agatgataag agtaaagaat cacgcagaca aatggttcaa aaggatcata
     6121 aacttgtcat gctatttgga gataatttat tagactttac agatccaaaa gaagctacag
     6181 ctgaatctcg tgaagcatta attgaaaaac ataaagacga tttcggtaag aaatatatca
     6241 ttttccctaa cccaatgtat ggtagttggg aagctacgat ttacaacaat aactataaag
     6301 caagtgacaa agcaaaagat aaattacgta aaaatgctat taagcaattc gatcctaaaa
     6361 caggcgaagt taaataatat atgaattgga cgtctacatg tacttaaagg tatatgtagg
     6421 cgtttttaaa ttgatcctta attttaaatg taccgtacaa aaataataga caattaattg
     6481 cattttccat aaatttgctt ttaatataaa aagttcgggt ataatgaagg ataagtgtat
     6541 gtataacatt acagagcgca acacgacgta cgtgcatcta agaatataaa caatgtttaa
     6601 atcatagtag tagggagaga aatgcatgtt tttagcttgg aatgaaatac ggcgcaacaa
     6661 attgaagttt ggactaatta ttggtgtgtt aacgatgatt agttacttgc tatttttatt
     6721 atctggattg gcgaatggtc ttatcaatat gaataaagaa ggcattgata agtggcaagc
     6781 agatgccatt gttctaaata aagatgccaa tcaaactgtg caacaatctg tttttaacaa
     6841 gaaagatatt gaaaataaat acaagaagca agctactttg aagcaaacag gggaaattgt
     6901 gtctaatggc catcaaaaag acaatgtttt agtgttcggt gttgaaaagt catcattttt
     6961 agttccgagt ttaatagaag ggcataaagc gactaaagat aatgaagtgt tagctgatga
     7021 aacgcttaaa aataaaggat ttaaaattgg tgacacatta tcactatctc aatcagatga
     7081 aaaattgcat atcgtaggtt ttacagaaag tgcaaaatat aatgcgtcac cagtcatttt
     7141 cacgaatgac gctaccattg ccaagatcaa tcctagattg actggagata aaattaatgc
     7201 agttgttgta cgtgatacaa attggaaaga caaaaaatta aaccaagagc ttgaagcggt
     7261 aagtattaat gactttattg aaaatttacc aggttataaa ccacagaact taacattaaa
     7321 ctttatgatt tcattcttat ttgtcatttc agctacagtt ataggcattt tcttatatgt
     7381 catgacatta caaaaaacaa gtttatttgg catattaaag gctcaaggat ttacgaatgg
     7441 ctatttagcg aacgtagtta tttcgcagac gctcatatta gcattatttg gtacggcatt
     7501 tggcttactg ttaacaggcg ttacaggtgc atttttacct gatgcagtac ctgtcaaatt
     7561 cgatgtacta acattgctcg tatttgcaat tgtgttaatg attgtctctg tattaggaag
     7621 tttattctcc attttaacaa ttagaaaaat agatccgtta aaggcgattg ggtaggaggt
     7681 gtagcaaatg ttgaaatttg aaaatgtaac aaagtcattt aaagatggga atcgtaacat
     7741 tgaagcggtt aaagatacaa attttgagat aaataaaggt gatattatag cattggttgg
     7801 accttctggc tctggtaaaa gtacatttct aactatggca ggtgctttac aaacgccgac
     7861 atctgggcac attttaatca ataaccaaga tattacgaca atgaagcaaa aagcattggc
     7921 aaaagttaga atgtctgaaa taggttttat tttacaagct acaaaccttg taccattttt
     7981 aacggtaaag caacaattta cattattgaa aaagaaaaat aagaatgtta tgtctaatga
     8041 agactatcag caacttatgt cacaattagg tctaacttca ttgcttaata agttaccttc
     8101 agaaatttca ggtggtcaga aacaacgtgt ggcgatagcc aaagcgttat atacgaatcc
     8161 gtcgattatt ttagcggatg aacctaccgc ggcgttagat actgaaaatg cgattgaagt
     8221 cattaaaatt ctacgtgatc aagccaaaaa aagaaagaaa gcatgtatta ttgttacaca
     8281 tgatgaacga cttaaagcat attgtgatcg ttcatatcat atgaaagatg gcgtccttaa
     8341 tcttgaaaat gaaacagtag aatagtttta ttaagccggt acatcatgtg ccggtatttt
     8401 tatgtttatg tattatttga ataaactttc acattcaatt aataataatt attatcgaaa
     8461 attagaaata ttccgtgaaa tataatattt tttgtagtaa aatggcctct aagtattcaa
     8521 tatttaaata tggggattga atataaaatt atcgtaatgg gggtcaatgg ttatggattt
     8581 aatgataggt actttatttt tatttttggt cttagtgatt tttacattat ttacatataa
     8641 agcacctaat ggtatgcgtg ccatgggagc attagctaat gcagcaatcg caacattttt
     8701 agtggaagca tttaataaat atgttggtgg cgaagtattc ggtgttaaat ttttagaaga
     8761 gctaggagac gctgcgggag gtctaggtgg tgtcgctgcc gctggattaa cagcattagc
     8821 tatcggtgta tcaccagtat atgcattagt tatagcagcc gcgtgcggtg gtatggattt
     8881 attaccaggt ttctttgcgg gttatatgat tggatatgtg atgaaatata cagagaaata
     8941 tgtgccggat ggtgtcgact taattggatc gattgtcatc ttagcgccat tagctcgtct
     9001 tattgcagta ttattaacgc cagtagtgaa tagtacattg attcgaattg gtgatattat
     9061 ccaaagtagt acgaatacga atccaattat catgggtatc attttaggtg gtattatcac
     9121 ggttgtcggc acagcgccat tgagttcaat ggcattgaca gcattattag gtttaacggg
     9181 tgtacctatg gctattggtg ccatggcagc atttagttcg gcatttatga atgggacgct
     9241 attccatcgc ttaaaattag gtgatcgtaa gtctacgatt gcagtaagta ttgaaccttt
     9301 atcacaagca gatattgtat cagccaatcc aattccaatc tatattacaa atttctttgg
     9361 tggtgcgatt gctggtttaa ttattgctat gtcaggttta attaacgatg cgacaggtac
     9421 agctacaccg attgcaggat ttttagtaat gtttggattt aatcatccaa tgactattgt
     9481 aatttatggt gtagtaatgg cgattgtagg tgcgcttgca ggttatcttg gttcaatcgt
     9541 atttaaaaaa tatccaattg ttactaagca agacatgatt aatcgaggtg cagttgacgc
     9601 atagcatcat catattgaat agtaaaaaca aataaaacat agtaacgtga ttcagtcgat
     9661 gaaaaaatcg ataatgagtc acgttttttt atagaaaaat ataagacata aaaatgtcat
     9721 aatttattgt cgacaaatat catactgtat aaacatttat cattttctca agtacctttt
     9781 acacgatgga atgaacttac tttttacgaa attatgcgta ttttataaac aaatatcatt
     9841 gatataacgg caaatgtaag cgtttacaac agaaataaca gcatgctacg atatttttgt
     9901 aaattcactg attcaagtat tttaagtcaa tatgaggagg gatgttatga gcgattctga
     9961 gaaagaaatt ttaaaaagaa ttaaagataa tccgtttatt tcacaacgtg aacttgctga
    10021 ggcaattgga ttatctagac ccagcgtagc aaacattatt tcaggattaa tacaaaagga
    10081 atatgttatg ggaaaggcat atgttttaaa tgaagattat cctattgttt gtattggcgc
    10141 agcgaatgta gatcgtaagt tttatgtgca taaagattta gttgcagaaa catcaaatcc
    10201 tgtaacgtca acacgctcta ttggtggcgt agcaagaaat attgctgaga acttaggtag
    10261 gcttggcgaa acggtcgctt ttttatctgc tagtggacaa gatagtgaat gggaaatgat
    10321 taaacgattg tccacaccat ttatgaattt ggatcatgtt caacaatttg aaaatgcgag
    10381 tacaggttca tatacagctt taattagtaa agaaggcgac atgacatatg gcttagcaga
    10441 tatggaagtg tttgactaca ttacgcctga atttttaatt aagcgttcac acttattgaa
    10501 aaaggctaag tgcattattg tcgatttgaa tttaggcaaa gaggcattaa acttcttatg
    10561 tgcctatacc acgaaacatc aaatcaaatt agttatcacc acggtttctt ccccaaaaat
    10621 gaaaaatatg cctgattcat tacatgctat tgattggatt atcacgaata aagatgaaac
    10681 agaaacatac ttaaatttaa aaatagaatc tactgatgat ttaaaaatag ctgctaaacg
    10741 ctggaatgat ttaggtgtta aaaatgttat tgtgacaaat ggcgtgaaag aactcattta
    10801 tcgaagtggt gaggaagaaa tcatcaagtc agttatgcca tcaaatagtg tgaaagatgt
    10861 tacaggtgca ggcgattcat tctgtgctgc agtagtatat agctggttaa atgggatgtc
    10921 tactgaagat atattaattg ctggtatggt taacgcaaag aaaacgatag aaacgaaata
    10981 tacagttagg caaaacctag atcaacagca actttatcac gatatggagg attataaaaa
    11041 tggcaaattt acaaaagtat attgagtatt ctcgagaagt tcagcaagca cgggagaaca
    11101 atcaaccgat tgtagcatta gaatcaacaa ttatttcgca tggtatgccg tacccacaaa
    11161 atgttgaaat ggcaacaaca gtagagcaaa ttatcaggaa taatggtgcc attccagcaa
    11221 ccatagccat tatagatggc aaaattaaaa ttggtttaga aagcgaagat ttagaaatac
    11281 tggcaactag taaagacgtt gctaaagtat ctagaaggga tttagcagaa gttgttgcga
    11341 tgaagtgtgt tggtgctact actgtagcga cgacgatgat atgtgctgca atggctggta
    11401 ttcaattttt tgttacagga ggtattgggg gcgtccataa aggtgcagaa catacgatgg
    11461 acatttcagc agacttagaa gaactgtcta aaacaaatgt cactgttatc tgtgcaggtg
    11521 ccaaatcaat tttagactta cctaagacga tggagtattt agaaacaaaa ggcgttccag
    11581 ttattggata tcaaacgaat gaattgccag cattcttcac tcgcgaaagc ggtgttaagt
    11641 taacaagttc ggttgaaacg ccagaacgac ttgctgacat tcatttaaca aaacagcagt
    11701 taaatcttga aggtggcatt gttgttgcta atccaattcc atatgagcat gccttatcaa
    11761 aagcatatat tgaggcaatc ataaatgaag ctgttgttga agcggaaaat caaggtatta
    11821 aaggtaagga cgccacaccg ttcttgttag ggaaaattgt agaaaaaacg aatggtaaaa
    11881 gtttagcagc aaatataaaa cttgttgaaa acaatgcggc gttgggtgct aaaattgctg
    11941 tcgctgttaa taaattattg taggtgatga tgcatgaata ttttattcgc tatcacaggg
    12001 atagcatttg cactatttgt tgcgttttta ttcagttttg atcgtaaaaa catagacttc
    12061 aaaaagacgt ttataatgat atttattcaa gtgttgattg tgttatttat gatgaacaca
    12121 acgattggtt taacaatctt aactgcatta ggctcatttt ttgaagggtt aataaatgtt
    12181 agtaaagcag gtataaactt tgtttttgga gatatacaaa ataaaaatgg ctttacgttc
    12241 tttttaaatg tgttactgcc attagtgttc atttctgtat taataggcat ttttaattat
    12301 attaaggtat taccatttat tatcaaatat gtaggtatcg ctattaataa aataacgaga
    12361 atggggcgct tagaaagtta ctttgctatt tcaacagcaa tgtttggaca accagaagta
    12421 tatttaacaa taaaagatat tattccaaga ttatctagag cgaaattata tacaattgcg
    12481 acgtctggta tgagtgctgt tagtatggca atgttgggtt catatatgca gatgattgag
    12541 cccaagttcg tagttacagc tgtaatgtta aatattttta gtgcgcttat catcgctagt
    12601 gtaatcaatc cctataaatc tgatgatagt gatgttgaga ttgataattt aactaaatca
    12661 acggaaacga aatcagtgaa tggaaaaaca ggaaaaccta agaaagttgc cttcttccaa
    12721 atgataggtg atagtgcgat ggatggattt aaaatcgctg ttgtagtagc cgtaatgttg
    12781 ttagcattta tttcattaat ggaagcaatt aatatcatgt ttggtagtgt tggtttgaac
    12841 tttaaacagc ttattggcta tgtgtttgca ccaatcgcat tcttaatggg gattccatgg
    12901 agcgaagctg ttccagctgg ctctttaatg gcgactaaat taattacaaa tgagtttgta
    12961 gcaatgcttg attttaaaaa tgtcctgggt gatgtatctg ctcgaacaca aggtatcatt
    13021 tcagtttact tagtaagctt cgctaatttt ggtacggttg gtatcatcgt aggttcaatt
    13081 aaaggcatta gtgataaaca aggagaaaaa gtttcatcct ttgcaatgag gctgttactt
    13141 ggttcaactc tagcttcaat catttcagga tcaatcattg gcttagtatt gtaaattaat
    13201 cgaagtatct aaattaaatt catggcaaag ctaaacccca tcaccaagtt ggcgcaacag
    13261 cgcatcataa cttggtgatg ggattttatc ataacaatct acttattcgt agccgttttt
    13321 gaaatgtatg ttgatggttt atctttttca aaaattgtta atcccgttat atctttttta
    13381 tgttttgaag ggacaatgaa gctaagtata taagcaaaga caaaagcaac tgtaaatgaa
    13441 atggtagata catagaaagg tgagttacct ttgccagcac cattatagac ataagcaaag
    13501 atgataccca atattaatcc acaaataaca ccgaatgtat tcgtacgttt agtgaaaata
    13561 ccaactgcaa atacaccagc taatggaaca ccgaataatc cagttacaaa caagaataaa
    13621 tcccataagt catttgaatt agaagcaatt aagtatagtg acattccaaa accgaaaata
    13681 cctgcaatga tgataatgaa acgtgcaaag ttaacttcgt gtcgctcgct atcttttccg
    13741 aagaagcgtt gcttaatgtc gattgaaata caagcagata tagaatttaa actagatgaa
    13801 atggtagact gtgcagcggc gaaaatggct gcaataagta atcctgctac aaatggtggc
    13861 atctcagtca aaatgaaata tggcactaca gatgatgtat tgaagccttt tggtaaaaca
    13921 gcttcatgtg tataaaatga atacagcatt gtacccatac cataaaataa gggtgctgaa
    13981 attaaagcta ggataccatt tgtccataac gatttatttg tttcttttaa actatcagaa
    14041 gcttgataac gctgcacgac gtcttgactc gctgtgtatt gatacaagtt gttgaaaata
    14101 tttcctagga aaataattgg aatggcagct gccgcagtat ttagtttcca attgtctgca
    14161 ctaattaatt ttttgtgctc aatcgcatct gcaaagacag tgccaaaacc gcctttaatg
    14221 ttcataacac ctagaataat aataactaaa gcgccgccta ataaaatgac gccttgaatg
    14281 aaatcactcc aaaccacacc ttcgaaacca cctaaaaatg tatataaaat acatagtaaa
    14341 cctacgagtg atgcaacgat ataagggttc atgtctgata cagatgtgat tgctaatgtt
    14401 ggtaagtaga taacaattgc aacacgccct aaatggtaaa cgacaaataa taatgagcca
    14461 atgacacgta tgctagggcc aaatctagct tctaaatatt catatgcaga tgttaccttt
    14521 aactttttaa agaaagggac atagaaataa ataagtaatg gaataattgc gacgatagca
    14581 atgttaccag cgatatatga ccaatctgtt aaaaatgctt tctctggtgt agacataaat
    14641 gtaatcgcac ttaacgtagt agcataaatt gaaaagccaa ctacccaaga tggcaagcga
    14701 ccacttgcgg taaagaaact attggtactt tggctcgcgc gcttggtaaa ataaacgcca
    14761 atgaacaaca tagctagtag ataaatgata acggcaaccc agtttagtgt gccaaatcca
    14821 acttctttca tgggcaacat cccctttaca atgtattgat tctttgatgt ctataaatcg
    14881 tattttgcaa tgagttgatc taatgtttgt cgatgtgctt cgttaaaagg tttgaaaggt
    14941 cttttcggta atcctgcatc aatgtcacga tgacgtaata tttctttcaa tgttggataa
    15001 atccccattg ataacactgt ttcgataatg tcgtttgaat catgttgtag ttggtaagct
    15061 tcttgaattt gaccttgtcg tgctaagtcg aagatttttc tagcgcggcg accattaacg
    15121 ttatatgtag aaccaattgc accatctacg ccagaaatcg tagcttgaac taacatttca
    15181 tcaaagccag ataagattaa tttgtctggg aatgcttttc taatacgttc gagtaggaag
    15241 aagttcggcg ctgtatattt aacaccaaca attttttcgt gattaaatag ctcgctgaat
    15301 tgttcaatag aaatattcac acctgttaaa tctggtattg cataaataat catattgttc
    15361 tgtgttgctt cgataatatc gaaatagtaa tctctaattt cttcaaaagt aaatggatag
    15421 tagaatggtg ttacggcaga aagtgcatca taaccgagtt ctgtggcata ttttccgagt
    15481 tcaatggctt catttaaatc taacgaacct acttgagcaa tcaatttcac tttatcccca
    15541 actgcctctt tggcaacctt gaaaacttgc ttcttctgct ctgtatttaa taaaaagttt
    15601 tcgcctgagc taccatttac ataaagaccg tctaattctt cagtttcaat ggcattttga
    15661 gcaatttgtt taagtccttg ttcatttact tgaccatttt catcaaaagg aacgagtaac
    15721 gctgcatata aaccttttaa atctttgttc attatgaagt ccctccaaaa atcatttgat
    15781 aatatagttt acagctataa ttgtaaacgc tatcataaaa tgtaacaata tctttttgaa
    15841 aattgtagtc atatttatgt ataattaatg aaaatgtttt tcaaaatcaa tagaaatgga
    15901 gtgagtaagg tgtattacat cgcaatcgat attggaggca ctcaaattaa atcggcagtt
    15961 attgataagc aattgaatat gtttgactat caacaaatat caacgccgga caacaaaagt
    16021 gagcttatta ctgacaaagt atatgagatt gtaacaggat atatgaagca atatcagttg
    16081 atccaacctg tcataggtat ttcatcagca ggcgttgttg atgaacaaaa aggcgaaatt
    16141 ggatacgcag ggccaaccat tccgaattat aaaggtacta attttaagcg attattaaaa
    16201 tcactgtctc cttatgtcaa agtaaaaaat gatgtaaacg ctgcattact aggcgaattg
    16261 aaattacatc aatatcaagc agaacggatc ttttgtatga cgcttggtac aggcattggg
    16321 ggtgcgtaca agaataatca aggtcatatt gataatggtg agcttcataa ggcaaatgaa
    16381 gttgggtatt tattgtatcg tccaactgaa aatacaacgt ttgagcaacg tgctgcaacg
    16441 agtgcattga aaaagcgcat gattgacgga ggatttacga gaagcacaca tgtgccagta
    16501 ttgtttgaag cagctgaaga aggtgatgat attgcaaaac aaatattgaa tgagtgggca
    16561 gaagatgtag cagaagggat tgcccaaata caagtcatgt atgatccagg gcttatatta
    16621 attggtggcg gtatatctga acaaggagac aatctcatta aatatatcga gccgaaagtt
    16681 gcacactatt taccaaaaga ctatgtttat gcaccaatac aaacgactaa gagtaaaaat
    16741 gatgcagcat tatatggctg tttgcaatga tagttgaaag aaggagtcat tctaaaatag
    16801 aatttgaaac cgttacgaga gatgagagct gttgttagtt ccacacatca cactctatct
    16861 aggaccaatc taaactatat caaccaacag tgtgccacgg gcatattaaa ttgaagacgg
    16921 ttgaacgtat agatctcaaa aatgtaaaaa agtatttggt attgaaatta aaaaagcacc
    16981 tagcaactcg ttaggacaat cacgatgatt gtctacagtt gcaggtggat ttgaatatac
    17041 tactagttat ttgttgtcta ggataataga tttagtatgt tgataagttt gactcagatt
    17101 tgtattttct aataaatgat aactcacgat attgattaaa aagagtgtcg caatttgtgt
    17161 gttgataaat tgatggtcgg tattacgcga ttgatccgtt gttaaaagta ctaaatctgc
    17221 acaatctgta agtttactac cttcgaaatt tgtgatggca acgacatatg caccatgaga
    17281 tttggcgact tccgctgctg aaattaattc cgaagtatta ccactatttg acatagcaat
    17341 aaacatgtcc gaatgagata gtagggatgc cgatattttc attaaatgtg aatcggtagt
    17401 aacattacct tttagcccca tacgaatcat acgataataa aattcagtcg ctgataaacc
    17461 agagctacct agtccagcaa agagtatatg tcgacttgat tggagtttgt cgataaaggt
    17521 ttggataatg tcgttatcaa taaattcacc agtttgttga atgatttgtt gatgatattt
    17581 atgaattctt tgaataattg ggctattttc aataactgtc tctgtcattt cttgttgaat
    17641 attaaatttt aaatcttgga aattctcata atctagctta tgactaaagc gtgtcatcgt
    17701 tgctggtgat gtaccaatcg catgggctaa ggagttaatc gttgaaaagg catcgctata
    17761 accattttgt cttatataat tgacgatgcg tttatcagtt tttgtaaata aatgttgata
    17821 acgttgaaca cgattctcaa atttcattgt gtcacccctt catcttaatg attactatta
    17881 tatatgaaaa atattttcaa gatagtaaaa agcattgata aaaattatct taatgatata
    17941 ttgtaaatga ctttacgtga aaaaacgact tatggagtga ggaataatgt taccacatgg
    18001 attaatagta tcttgtcagg cactagcaga tgaaccattg cattcatctt ttattatgtc
    18061 gaaaatggca ttagctgcgt atgaaggtgg tgctgttggt attcgcgcaa atactaagga
    18121 agacatttta gcaattaaag aaacggtaga tttaccagtt attggcattg tgaaacgtga
    18181 ctatgatcac tcagatgttt tcattactgc aacgtcaaaa gaagttgatg aactgataga
    18241 aagccaatgt gaagtcattg cattggatgc aacgttacag caacgtccga aagaaacgtt
    18301 agacgaatta gtatcatata ttagaacaca tgcaccgaac gttgaaatca tggctgatat
    18361 cgcgaccgtt gaagaagcta aaaatgccgc acgacttggc tttgattata ttggcacgac
    18421 gttacatggc tatactagtt atacgcaagg acaattactt tatcaaaatg acttccaatt
    18481 tctaaaagat gtactacaaa gtgttgatgc aaaagttatt gcggaaggta atgtcattac
    18541 accggatatg tataaacgcg tgatggactt aggcgttcat tgttcagtcg ttggtggtgc
    18601 gataacacga ccaaaagaaa ttacgaaacg ttttgttcaa gttatggaag attaaatgat
    18661 aacgataaaa aaacgagatg accatcatta attaaaggta cctaattatc ttaggtggct
    18721 gaatgaatgt aatgggttca tctcgttttg tttgtttacg atagtgattt tattttcaat
    18781 ttgaattatc caaaaataag taaagcgacg gggatggtga ttaatagcga caatgccacg
    18841 cgtaaaaacc aaatgatgat gagtttccag acaggtattt taatttcagt tgctagtata
    18901 catggcacta atgctgagaa aaagataatg gctgatacgc ttactacacc gacgacaaat
    18961 ttagtactca ttgcagcttt agttactaac aaagatggta gaaacatttc tacaatagaa
    19021 atcgctgacg cttttgcaag tacagcctga tcagcaattg ggaaaatata aataaatgga
    19081 tagaatatat agccaagcca atcaatgaat ggtgtatagt tcgctacaat cagtcctaaa
    19141 aaaccaatcg ataatataga aggcaaaata ccaacagtca tttctaaacc gtctttaaaa
    19201 ttgtcccaaa cgttcttcac gagagatggt gttaatgcat tttgtttcat cgcctctgca
    19261 tatgcagttt tcagtctgct tccttcaata gcaacttctt gttctccttc ttgtccgtta
    19321 taatattctg ttgattcatt ggtgattggc ggtagccatg cagtaattgc agtcacgaca
    19381 aatgtgatga ctaaagttat ccaaaagtat aaattccaat gcggcattag ccctaaagtt
    19441 ttagcaacga taatcataaa agttgctgaa actgttgaaa agccagtcgc aataatcgtg
    19501 gcttctcgtt tgttgtacat cccttgctta tagacacgat tagtaatcaa taatcctaag
    19561 gaataactgc cgacaaacga agctactgca tcgacagcgg attttcctgg tgttttaaaa
    19621 ataggtctca taataggctc catataaaca ccgacaaatt ctaataagcc atagcctact
    19681 aataaagaaa gcgcaattgc acctactgga attaagatac ttaatggcat cattaatttt
    19741 tcaaacaaga acggaccata gttagcttta aatagtattg atggaccgat tttaaataca
    19801 tacattatac caatcattgc acctgcaact ttaaataatg taatgaccaa gtttgtgatt
    19861 gaagtcataa aagtacgtct cactattggt aacgctgtac caattaaaat cataatcagt
    19921 gcaacatagg gcataagtgg acctatgatt gagcgaatgg ctagatgaac atgatcgacg
    19981 aaaatagtgt tgttaccatt aatcgtaaaa ggaataaaga aacatagtat gcccactaaa
    20041 ctatagacaa aaaaacgcca tgcacttggt tgttgtgcat tagaatgata ttgattcatt
    20101 aaagcaaccc ctttgtttaa atgaatacac aaaactgtat gatgcatctt ccccttaatg
    20161 agatgaatca ttattttaat ttagaaaaat ctgaaaactt actataattg tatagtttga
    20221 attattttca taccaataca aattaactaa ttatatatag attgaaacta tattacttaa
    20281 taaaatattt atcttaaatg ttgttgtgtt gatttaacgc cacaactaaa agtgtttata
    20341 aattatttgg aaatgcacat atttgtaaat gattagtatc gatttaatat cgtattatta
    20401 aatttttatt aattttgtag tcttaatcaa aaaataatat atgtcatgtt atattgaagg
    20461 tgcagttgtt tttcattctc aagagggggt caaaaaaata cttttgaggt gattatatgt
    20521 taagaggaca agaagaaaga aagtatagta ttagaaagta ttcaataggc gtggtgtcag
    20581 tgttagcggc tacaatgttt gttgtgtcat cacatgaagc acaagcctcg gaaaaaacac
    20641 caacgtccaa tgcagcggca caaaaagaaa cactaaatca accgggagaa caagggaacg
    20701 cgataacgtc acatcaaatg cagtcaggaa agcaattaga cgatatgcat aaagagaatg
    20761 gtaaaagtgg aacagtgaca gaaggtaaag acacgcttca atcatcgaag catcaatcaa
    20821 cacaaaatag taaaacaatc agaacgcaaa atgataatca agtaaagcaa gattctgaac
    20881 gacaaggttc taaacagtca caccaaaata atgcgactaa taatactgaa cgtcaaaatg
    20941 atcaggttca aaatacccat catgctgaac gtaatggatc acaatcgaca acgtcacaat
    21001 cgaatgatgt tgataaatca caaccatcca ttccggcaca aaaggtatta cccaatcatg
    21061 ataaagcagc accaacttca actacacccc cgtctaatga taaaactgca cctaaatcaa
    21121 caaaagcaca agatgcaacc acggacaaac atccaaatca acaagataca catcaacccg
    21181 cgcatcaaat catagatgca aagcaagatg atactgttcg ccaaagtgaa cagaaaccac
    21241 aagttggcga tttaagtaaa catatcgatg gtcaaaattc cccagagaaa ccgacagata
    21301 aaaatactga taataaacaa ctaatcaaag atgcgcttca agcgcctaaa acacgttcga
    21361 ctacaaatgc agcagcagat gctaaaaagg ttcgaccact taaagcgaat caagtacaac
    21421 cacttaacaa atatccagtt gtttttgtac atggattttt aggattagta ggcgataatg
    21481 cacctgcttt atatccaaat tattggggtg gaaataaatt taaagttatc gaggaattga
    21541 gaaagcaagg ctataatgta catcaagcaa gtgtaagtgc atttggtagt aactatgatc
    21601 gcgctgtaga actttattat tacattaaag gtggtcgcgt agattatggc gcagcacatg
    21661 cagctaaata cggacatgag cgctatggta agacttataa aggaatcatg cctaattggg
    21721 aacctggtaa aaaggtacat cttgtagggc atagtatggg tggtcaaaca attcgtttaa
    21781 tggaagagtt tttaagaaat ggtaacaaag aagaaattgc ctatcataaa gcgcatggtg
    21841 gagaaatatc accattattc actggtggtc ataacaatat ggttgcatca atcacaacat
    21901 tagcaacacc acataatggt tcacaagcag ctgataagtt tggaaataca gaagctgtta
    21961 gaaaaatcat gttcgcttta aatcgattta tgggtaacaa gtattcgaat atcgatttag
    22021 gattaacgca atggggcttt aaacaattac caaatgagag ttacattgac tatataaaac
    22081 gcgttagtaa aagcaaaatt tggacatcag acgataatgc tgcctatgat ttaacgttag
    22141 atggctctgc aaaattgaac aacatgacaa gtatgaatcc taatattacg tatacgactt
    22201 atacaggtgt gtcttcacat actggtccat taggttatga aaatcctgat ttaggtacat
    22261 ttttcttaat ggatacaacg agtagaatta ttggtcatga tgcaagagaa gaatggcgta
    22321 aaaatgatgg tgtcgtacca gtgatttcgt cgttacatcc atccaatcaa ccatttatta
    22381 atgttacgaa tgatgaacct gccacacgca gaggtatctg gcaagttaaa ccaatcatac
    22441 aaggatggga tcatgtcgat tttatcggtg tggacttcct ggatttcaaa cgtaaaggtg
    22501 cagaacttgc caacttctat acaggtatta taaatgactt gttgcgtgtg gaagcgactg
    22561 aaagtaaagg aacacaattg aaagcaagtt aaattcatct tctgaattta ataggctatg
    22621 taaatcgtgc tgttatcatg gcacatcaga tataagtagc atcacagtgt tgaatttcaa
    22681 aatagtaaag tgaaataaag cgcctgtctc attagcgaaa actaaaggga caggcgtatc
    22741 tgtttatgag cttaataaat tgtatgaata atatggttga tcgaataact gtttatcatg
    22801 atgataaatt gagtttttta aaataatgat atattacacc attgttatag cgtttaagaa
    22861 atcaacaact ttacgataaa tagtgattgc ttcgtcatta ggtctacgat caaaatcatg
    22921 ctcgttttta ttcacgcgtt caaatgttga atgtggaaca tgattcatga tatgttcgct
    22981 ttcctcaacg ggaacatcat aatcgccatt acaatgcgca atgaaaacag gtggaagtgt
    23041 tttaagttca tctggtgcaa tattatattt tgaatcagta taatcagcaa tgttaatcat
    23101 atttatccat ttacctgtgc cacgtgcata aacgtagatt aaaaaacgtt gtgcgatttg
    23161 atcttgaaca accggtgttg gtgaagtgag ttgtgcaatc attgtttcgt ttatgctttg
    23221 agctattttt gcgtaataac tattagttgt tttaaaaggt tcagtgttga tgcgactata
    23281 accataaaaa tcaataacac catcaatatc tctgtctcgt gcaattaata gacttaaata
    23341 tgcacctgat gatctgccaa aggtaaaaat agggcaatta gaatattgtg attgaatcgc
    23401 atcgaatgat gcgtagacat cctcaataat gcaatcgaga cttacttctg gtaataaacg
    23461 ataacttagt tgaattaaat cgtaatgttc cgtaaggata tcgatatact gtggggataa
    23521 atcgttagct ttaccgaaca ttaatccacc accgtggatg tagacaataa cgccttttgt
    23581 tggttgattt tttgctttaa taattgtgta aggtaatgca aatgcatctt tagtaattac
    23641 tttatattta atttcagtca cgatttaata ggctccttat ttttgatatt gatgtcatta
    23701 taacactgtc ttaaatttcc atgaaaaata gtcttaagac gatgagtcat gataattctg
    23761 ttccaattga cgtaaagcgt cacgggtatg cttctttaga ccttccccat aatccatcat
    23821 tttaacaata tctttaaaag cagcatgtgg aatggctaaa tcttctaaat ctgccataga
    23881 aaattcaaga ttgatatcat gtggtcgctg ttcagcaagt ttatgcacaa agtcaggttc
    23941 tgtgacaaaa ggcgaagaca tgccgaccat atctgcatgt tgtaaagcat ctaaagcaga
    24001 ctctggagaa ttaatcccgc cacttgcaat taaagggata cgacctgcta aatgttcata
    24061 gacaatttgg ttaactggtc gaccgaaatg atcacctggt gtacgagacg tattttgata
    24121 aatatgtcga ccccagctag cgattgctaa gtattggatg tttgaaacgt ccatgaccca
    24181 atcgattaat tggttgaact cgtcaatggt atatcctaaa tcactgcctc tggtttcttc
    24241 tggcgttgct cgaaatccta aaataaaatt gtcaggtgct tctttatcaa tcacttcttg
    24301 taccgcacgc ataacttcta aacataatct tgcacgattt tttaatgagt cggcaccgta
    24361 atggtctgta cgtctatttg aaaaagttga gaaaaatgtt tgaatcagca aacgttgtgc
    24421 aatcgaaatt tccacaccat caaaacctgc tttaatcgcg cgtaatgtag catcgcgata
    24481 ctgctgaatg atgctattga ttttctcatg agacatggcg ataacaacgt gttcaatcgg
    24541 tgaatgcaaa gtcataggac ttggtccata cacctttcca aaatttaaaa tggcttgatt
    24601 tgaaaaacga ccagcatgcg ctagctggat aatagcgagg ctaccatgtt gtttcatcgt
    24661 agatgccatg ttagttaatc cagggataca agcatcatga tcaatattaa agccatattc
    24721 aaacaattta ccataaggtt caatgtaagc agcgccggtg acttgcattc cagctgaatt
    24781 agagcgacgt gcagcataag ccaagtctgc ttttgtaata tagccttctt ttgttgatgc
    24841 gtttacggtc attggtgata atacaaagcg attcgaaatt ttgatgccat taggtaagtg
    24901 gattgattgt aaaagtggtt tgtatcggta catactatga ttccttttct attcaatatt
    24961 gttttcaaag taccatggaa agaatgaata atcaatgatg aacagtcttg atagaataga
    25021 attggtacat ggaaaacatt tttaaaattg aactaatgaa tggcatttgt aggtctgaaa
    25081 atatgaatat gaaaaagaaa aataaaggcg aaaagatata aaagttaatt gaaaaacgtt
    25141 atcatatacg tgggtatatg aagagggaat ggtattaaga acgctaaaat gttatgtcgg
    25201 tttgacatga caggataagt ttggagatga cggattggtt aaattaagcg tattagacta
    25261 tgccttaata gatgaaggta aggatgcaca aaaggcattg caagattcag tgacacttgc
    25321 aaaattagca gatcgacttg gctttaagcg aatttggttt acggaacatc ataatgtacc
    25381 agcgtttgcg tgtagtagtc cagaactttt gatgatgcat acattggcgc agacaaatca
    25441 catacgagtt ggctctggtg gtgtgatgct gccgcactat cgaccttata aaattgctga
    25501 gcattttaga atgatggcag cgttatatcc aaatcgtatt gatttaggta ttggtaataa
    25561 tccaggtact actatggtaa agcaagcttt agatggaata aatcctacat atgatagtta
    25621 cgatgaatcg atttcgttat tacgtgatta tcttacaata aaggataaac caagtgcgca
    25681 tacgttaggt gtccaaccac acattgatca ttttccagaa atgtggttat taagtagtag
    25741 cgcaacatct gccaaaatag ctgccgaact aggtataggg ctttctgttg gaacattttt
    25801 gctaccagat ataaatgcga tacatgcagc gaaggataac attgatattt acaaaaaaca
    25861 tttccaagca tcaacgatta aaatggacgc aaaggtgatg gcatctgtat ttgtcattgt
    25921 agcagataac gaagcggaag tagcagcatt gcaacatgcc ttagatgttt ggttattagg
    25981 taaattacaa tttgcagaat ttgaacattt tccttcagta gacacagcac aaaagtataa
    26041 gcttaatgat cgagacaaag agatgattca agtacatcaa gcacgcatca ttgcaggcac
    26101 acaagaacag gttaaagcac aattagatga tttcattgct acgtttgaag ttgatgaggt
    26161 gttagtagca ccgcttattc caggtattga acagcgttgt aaaacattaa aattactcgc
    26221 ggaaatttat ttgtagcatt ttaaatagaa gagaaaggat gaagataaga tgaaaaagtt
    26281 agccaattat ttatgggtag aaaaagtagg agatttgtat gtgtttagta tgacacctga
    26341 attgcaagat gatattggga cagtaggtta tgttgaattc gtaagtccag atgaagttaa
    26401 agtggatgat gaaattgtga gtatcgaagc atcgaaaacg gtcattgatg tgcaaacgcc
    26461 attgtcagga acgattattg agcgaaatac aaaagcggaa gaagaaccga caattttaaa
    26521 ctctgaaaaa ccagaagaaa attggttgtt caaattggat gatgtcgata aagaagcatt
    26581 cctagcatta ccggaggctt aaatggaaac gttaaaatca aataaagcga gacttgaata
    26641 tttaatcaat gatatgcgtc gagagagaaa tgacaatgac gtattggtaa tgccatcttc
    26701 atttgaagat ttgtgggaat tatatcgagg cttggcaaat gtcagaccgg cattacctgt
    26761 aagtgatgaa tatttagctg tacaagatgc tatgttaagt gatttgaatc atcaacatgt
    26821 tacggatttg aaggatttga agccgataaa aggtgacaat atctttgttt ggcaaggtga
    26881 tatcacgacg ttaaaaatcg atgctattgt taatgctgca aatagtcgtt ttctaggatg
    26941 tatgcaagct aatcatgact gcattgataa tattattcat acaaaagcgg gtgttcaagt
    27001 tcgacttgat tgtgcagaga tcattcgaca acaagggcgc aatgaaggtg taggtaaagc
    27061 caaaaaaaca cgtggatata atttgccagc aaagtatata attcatacgg ttggtccgca
    27121 aatacgtcga ttgcctgttt caaagatgaa tcaggacttg ttagctaaat gttatcttag
    27181 ctgtcttaaa ttggctgatc aacatagttt aaatcatgtc gctttttgct gtatatctac
    27241 aggtgtattt gcttttcctc aagatgaagc agcagaaatt gctgttcgaa cagtagaaag
    27301 ctatctcaaa gaaacaaatt caacattgaa agtcgtgttc aatgtattta cagataagga
    27361 tttacaactg tataaggagg cattgaaccg tgatgcagag tagtaaatgg aatgcaatgt
    27421 ctcttttaat ggatgaaaag acaaagcagg ctgaagtatt gcgtactgcg attgatgaag
    27481 cagatgcgat agtgattgga attggtgcag gcatgtctgc atctgacgga tttacatatg
    27541 taggagagcg ttttacggaa aatttcccag attttattga aaaatatcgc ttctttgata
    27601 tgttgcaagc gagtttacat ccttatggca gttggcaaga gtattgggca tttgagagtc
    27661 gttttattac attaaattat ttagatcaac ctgtaggtca gtcttatctc gcattaaaat
    27721 ccttagtgga aggtaaacag taccatatca taactacgaa tgcagacaat gctttcgatg
    27781 ctgctgaata tgatatgact catgtatttc atatacaagg ggagtatata ctgcaacagt
    27841 gtagtcagca ttgtcatgct caaacgtatc gcaatgatga tttaattcgt aaaatggttg
    27901 ttgcgcaaca agatatgctt ataccttggg agatgattcc aagatgtcca aaatgtgatg
    27961 ctccaatgga agtgaataaa cgtaaagcgg aagttggcat ggttgaagat gctgaatttc
    28021 atgcgcaact acaacgttat aatgcttttc tagagcaaca tcaagatgat aaagtgttgt
    28081 atttggaaat tggaattggt tatactacac cacaatttgt gaagcatcct tttcagcgta
    28141 tgacacgtaa aaatgaaaat gcaatttata tgacgatgaa taaaaaggca tatcgcattc
    28201 cgaattcaat tcaagaacgt accatacatt taactgagga tatctcaaca ttgattacaa
    28261 cagcactccg gaacgacagt acaacgcaaa ataacaacat tggagagaca gaagatgtac
    28321 ttaatagaac cgattagaaa tggagaatat attactgatg gtgcgattgc actggctatg
    28381 caagtttatg ttaaccagca tatcttttta gatgaagata ttttattccc ttattattgt
    28441 gatccaaaag tggaaattgg acgttttcaa aatactgcta tagaagtgaa tcaagattat
    28501 atagataaac acagtattca agtagttcgc cgagatactg gtggtggcgc tgtgtatgtt
    28561 gataaaggtg ccgttaatat gtgttgtatt ttagaacaag acacttcaat ttatggtgat
    28621 tttcaacgat tttatcaacc agctataaag gcattgcata cattaggtgc aacagatgtg
    28681 atacaaagcg gtagaaatga tttaacattg aacggcaaaa aagtgtcagg cgccgcaatg
    28741 acattaatga acaatcgtat ttatggcggt tattcgctat tacttgatgt taattatgaa
    28801 gcaatggata aagtgttaaa gcctaatcgc aaaaagattg catcgaaagg gattaaatct
    28861 gtgcgcgcac gtgttggtca tcttagagaa gcactggatg aaaagtatcg tgatataacc
    28921 attgaagaat ttaaaaattt aatggtgacg cagattttgg gaatcgatga cattaaagag
    28981 gcgaaacgat atgaattaac ggatgcagat tgggaagcga ttgatgaatt agctgataaa
    29041 aagtataaaa attgggattg gaattatggg aagtcaccta aatatgaata taatcgaagt
    29101 gaaagattat catcaggtac tgtagatatt accatttctg ttgaacaaaa tcgtatcgca
    29161 gattgtcgta tttatgggga tttctttgga caaggtgata taaaagatgt ggaagaagca
    29221 ttacaaggaa caaaaatgac aagagaagat ttaatgcatc agttaaagca attagacatc
    29281 gtttattatt ttggtaatgt tacggtagaa tcattggttg agatgatttt aagttaatat
    29341 tgtttaggcg ttaatgtcac accctcaatg aatatgtgta tttgctttta aaatggtgac
    29401 tatgtagtta tgtaatttga ttatacgatt gaaaatgaat ttagttaatt agcaaagaca
    29461 tcatatttat agcgtttgtg tttattagtg attgggtatt tgaaaatggt taatgatagt
    29521 ttttaaagga ataaattcat tttcatttat ataagtaaga ttaaatacta gctactaaag
    29581 tctatttata tacgtcaaaa tataatgact gctataatga gtaatcaata gacacaaaga
    29641 ggagattatg tgatgaataa taaagtatta gtaaccggtg gtacagggtt tgttggcatg
    29701 cgaattattt cacgattatt agaacaaggt tatgaggtac aaacaacgat acgtgattta
    29761 agtaaagctg ataaagtaat taaaacaatg caagacaatg gcatttccac agagcgatta
    29821 atgtttgtcg aagcggattt atcacaagat gaacattggg atgaagcaat gaaagattgt
    29881 aaatatgtct tgagtgtagc atctccggtg tttttcggta aaacagacga tgcagaagtg
    29941 atggcgaagc ctgccattga aggcatacaa cgtattttaa gagctgcaga acatgctggc
    30001 gtgaagcgtg tggtgatgac tgcaaacttt ggtgcagttg gttttagcaa taaagataaa
    30061 aattcaatca caaatgaaag tcattggaca aatgaagatg aaccaggctt atcagtatat
    30121 gaaaaatcaa aattgttagc tgaaaaggca gcgtgggatt ttgttgagaa tgaaaataca
    30181 atagtagaat ttgccacaat caatccagtt gcaatttttg gaccatcatt agatgcacac
    30241 gtttcaggaa gtttccactt gttagaaaac ttattaaatg gttcaatgaa acgtgtaccg
    30301 caaattccat tgaatgttgt tgatgtgaga gacgtagctg aactacacat tttggcaatg
    30361 acaaatgaac aggctaatgg caagcgattt attgctacag ctgatggaca aattaatttg
    30421 ttggaaattg caaaattaat taaagaaaag agacctgaaa tagctcaaaa agtttctact
    30481 aaaaaattac cagactttat tttgagtcta ggtgctaaat ttaatcatca agctaaagaa
    30541 ggtaaacttt tattagatat gaaccgcaat gtaagtaacg aacgtgcaaa aacattactt
    30601 ggttgggaac cgattgcgac acaagaagaa gcaattttag cagcaattga tagtatggct
    30661 aaatttcatt taatataata caaaaacacc gtccataagt aagtggcttt cctcttgata
    30721 aaagaggcat tcactcaata tgtgacggtg ttttatatat ttacgttaac actattgctg
    30781 tggcttttga cggcctttta ataaaattgc tgtcgcacct acgataataa taaatagaat
    30841 cgcaccaaat aatcccatat attttactgc gttaccgaac acgataccga cagttaaaaa
    30901 gtctgtatct gagaatgttg ttgcagcacc acctaattcg cctaaaaatg gcaagaataa
    30961 taatggtaaa aacgtgatta ggataccatt tagagcggcg ccagcaacag cacctttaat
    31021 accgcctctt gcattaccga atacagcagc cgttgcacct aagaagaagt gtgcaactac
    31081 gccaggtaaa atgacgacgc caccaaataa gaataagata aacataccga tgacacctgt
    31141 aataaagctg acaaagaatc caattaatac tgcattttgt gcataaggga acacaatagg
    31201 gcagtctaat gcaggtttag aatttggtac aagcttttca gaaattcctt taaatgctgg
    31261 gacgatttca gctaagatta aacgaacgcc cgttaaaata ataaatacac cagcagcaaa
    31321 tgtcacacct tgaattaaag aaaagacaat aaagttttga ccatcactaa tagattcgtg
    31381 tacataacta acgcccgcaa ataagcatgc gatgaagtaa agtaatgcca ttgtaatcga
    31441 gatactaatt gtactttctc gtaagaaact taagcctttt ggaaatttaa tctcttccgt
    31501 tgatttagac ttacctttga ataattgacc tacagcacct gcggcaaagt aactgattga
    31561 gccaaaatga cctaacgcta cttggtcatt ccctgtaatt tttcgcatcg taggttggag
    31621 taatgcaggt aatactgcca tgattaatcc taatacgagt gcgccgataa caattgttag
    31681 ccagccttta atatgactga ctgttaaaat gattgctaaa aacgcagcca tgtaaaatgt
    31741 atgatgacct gttaaaaaga tatattttaa attagtgaag cgagcaatta aaatattaac
    31801 aatcatgcca cagaccatga tgagtgcagc tgttgttcca aaatctttta aggctagtga
    31861 gacgatagct tcgttgttag gtacgatatc ttgcacacca aatgcgtgtt ggaatatttt
    31921 gccgaatggt tcaagagatc gaacgacgac atcagcacct gcacttaaaa ttaagaagcc
    31981 taatatcgtt ttaatggttc ctgaagtgat cgttgcggca ggttttttct gaacgattaa
    32041 acctataaag gcaatcagtg caacaagaat ggctggttga cttaaaatat cgactataaa
    32101 attaaggatt gcttgcatag gtcgtacctc ctttaaatca tgttaagttg ttgtaatttt
    32161 tctgagagct tttgttgtaa ttcagcttta tctaaaatat tatcaagaac taagacatcc
    32221 cctaggcgtt cggcattttc agctaaatct ctaccacaaa taaacaagtc agccatctct
    32281 ggacttgctg tcataatgtc actatgttca acttcgatat cagatggtgc attaagttgc
    32341 ctaagtgctt cttgtgcgtt catttctacc ataaaactac ttcctaaacc gtggccacat
    32401 actactaaaa ttttcatatt aatcatgctc ctttaaaatg tttttaatgt cttgtgcgtt
    32461 ttttgcagtt aatagttgct ggactgtttg gttatcgccc agtacggttg ctaaattttg
    32521 taatacagat aagtgtgaat gattgtcgat ggcactcaat acaaaaatga gagatgcgta
    32581 gtgatcttca tcacaaaatg ccacatgttg attcaacttt aatagactta aaccaacttg
    32641 atgtacgtca ttgttcggtc ttgcatgtgc aattgcaatt tcaggtgcga taacgatata
    32701 aggtccaagt tcattaacgc tatcaatcat tgcttgaaca tagccttgtt caataatttg
    32761 ttcttgtagt aatggctgag aagctatagt tatagcttca gtccaatcat ttacttgttc
    32821 ttttacaatg atgcgtgttg ttgacaaaat gtctaatgac acgttattaa acctcctttg
    32881 tcatagttaa agcaatgtgt tgtttaattt taaaaatatt cccatctaag aaatcttgtc
    32941 gatataagtc gttgcttaag cattcgctta actgtcccaa tgcctttaaa tgtgcattgg
    33001 ggtggtccgt tgctaatgta attacaaggt gaacgggatc gttagcttta ctaccaaaga
    33061 taatcccttc agtgaaatat gttagtgcga aacctacacc attctgtaca taatcagtac
    33121 cagcgtgaat aagtgcaata tgtggactaa tgaccatata tgacccgaat tgttcaaatt
    33181 gttttaaaat tgcagctgta taatttgaat agacaatgcc atcattgatt aaaggttgca
    33241 cagccactgc aattgcggat tcaattgata atggttgttc atttataatg atgcgatgtt
    33301 caggcaataa atctgcgagt gacttgccat cagttgccat tttcatgact cgttgttctc
    33361 ttgagtcatt gataatttga ttcaattttt gacgagattg ttgattgata aatggatcga
    33421 catgaataac tggtacagct gatatttcac aaggtactgt tgaaatgaca taatcaatgt
    33481 tatcttgcaa taatcgactt tcttccaatt gataaatgga ataggcatcc caaatgtgaa
    33541 actcaggata cagatgattt agttttgatt ttaaaagttg cgacgtgcct ataccagaac
    33601 cacatagtaa gacaacctta atcattgatt gtttatgtgt tgcaacacgc tctatacttg
    33661 atgcgaagtg aattgtaatg tatgttaatt catcttcgtt gaagcgaata gcagcatctt
    33721 gttcaattgg gctaatatgc ttgctaacgg cttcaatgat ttgaggatag cgacgcataa
    33781 cttcttgcct caaaggatta ggttgtagca tatcgtattt aatacgatgt atagctggtt
    33841 tgatatgtgt gatcagactg gtatgcaact tgttgtcttt tgacatatca atgcctaatt
    33901 cttggctaac acaagtgatc aattcatgta tattttgcga taaatcatgg tattcaaagg
    33961 taattgaaga tgctgtatgt tcggtcattt tagagcctag taaatgtaac gtgataaaga
    34021 taatttcaga ctctggaaat gtgacattac aactgcgttc taagttttct atcatttttg
    34081 aagcaatagc atactgatta gtatgtcgcc atttatcaat ttcattgata ggtatatcga
    34141 acgaaaaatt ttcatttaaa cgctgaatgg caatgagtat atgatagatt aagccatcga
    34201 tagccgactg aactaaatga taattttcac tatttaatgt cttaataatg gcacggcgaa
    34261 ccaatgcgat tgattctgaa ttaaagatat ccgcctctat aaaaggtgca gcttgtttca
    34321 tatattgatg tataaagtgt gcatacgctt tacgataatg atcttcctca ccaataacat
    34381 tgaatccttt attgtggaca taatttaact ttaaatggta ttgatctagt tgggcttgaa
    34441 tcattttaat atcatctgca attgtccgac gcgaaacatt aacatcttgc gcaagttgct
    34501 ttgttgaaac aggatcggtt gtttcgaata actttaaagc gatatgtgtg agtcgttcat
    34561 cttttgaaaa atgaatttga tttgttagat tgtgctctaa ttcatttaat agtgtcgcgt
    34621 gagctgttgt tactttgatg cctgcagctt tattacggct gacttggtaa tgataagttt
    34681 cagcatattg ctcaatatat gctatatcat attgaatggt acgaggtgat acaccaagtt
    34741 gattagcaat ggtattgatt ggaataaacg tttgctcatg aattaaaaga tacaaaattt
    34801 cgatttgtct ataacttaac aacgtaatat cctcctattt gtaattgtaa gcgatttctt
    34861 aaaaacgtag atatgcaatc tctttcatat tttaatccga aaaattgcat atcaaaatgt
    34921 ttatggcgca agattttata ggaactttta aaataaatta gatattcatg ttgacaattt
    34981 aaaaatgtcg cagtatattt agttagacat ctaacgaaat ggtggtgcaa taaatggaat
    35041 tcacttattc gtatttattt agaatgatta gtcatgagat gaaacaaaag gctgatcaaa
    35101 agttagagca atttgatatt acaaatgagc aaggtcatac gttaggttat ctttatgcac
    35161 atcaacaaga tggactgaca caaaatgata ttgctaaagc attacaacga acaggtccaa
    35221 ctgtcagtaa tttattaagg aaccttgaac gtaaaaagct gatctatcgc tatgtcgatg
    35281 cacaagatac gagaagaaag aatataggac tgactacctc tgggattaaa cttgtagaag
    35341 cattcacttc gatatttgat gaaatggagc aaacactcgt atcgcagtta tctgaagaag
    35401 aaaatgaaca aatgaaagca aacttaacta aaatgttatc tagtttacaa taaatggtaa
    35461 gtgtgactgg tagaaatcag tcactttatc tttaatatta tagttagata tctaattgtt
    35521 agtaagctaa ttattggaaa agacaaggag tattgaacaa tgaaagacga acaattatat
    35581 tattttgaga aatcgccagt atttaaagcg atgatgcatt tctcattgcc aatgatgata
    35641 gggactttat taagcgttat ttatggcata ttaaatattt actttatagg atttttagaa
    35701 gatagccaca tgatttctgc tatctctcta acactgccag tatttgctat cttaatgggg
    35761 ttgggtaatt tatttggcgt tggtgcagga acttatattt cacgtttatt aggtgcgaaa
    35821 gactatagta agagtaaatt tgtaagtagt ttctctattt atggtggtat tgcactagga
    35881 cttatcgtga ttttagttac tttaccattc agtgatcaaa tcgcagcaat tttaggagcg
    35941 agaggtgaaa cgttagcttt aacaagtaat tatttgaaag taatgttttt aagtgcacct
    36001 tttgtaattt tgttcttcat attagaacaa tttgcacgtg caattggggc accaatgatt
    36061 tctatgattg gtatgttagc tagtgtaggc ttaaatatta ttttagatcc aattttaatt
    36121 tttggttttg atttaaacgt tgttggtgca gctttgggta cagcaatcag taatgttgct
    36181 gctgctctgt tctttatcat ttattttatg aaaaatagtg acgttgtgtc agttaatatt
    36241 aaacttgcga aacctaataa agaaatgctt tctgaaatct ttaaaatagg tattcctgca
    36301 tttttaatga gtatcttaat gggattcaca ggattagttt taaatttatt tttagcacat
    36361 tatggaaact tcgcgattgc aagttatggt atctcattta gacttgtgca atttccagaa
    36421 cttattatca tgggattatg tgaaggtgtt gtaccactaa ttgcatataa ctttatggca
    36481 aataaaggcc gtatgaaaga cgttatcaaa gcagttatca tgtctatcgg cgttatcttt
    36541 gttgtatgta tgattgctgt atttacaatt ggacatcata tggtcggact atttactact
    36601 gatcaagcca ttgttgagat ggcgacattt attttgaaag taacaatggc atcattatta
    36661 ttaaatggta taggtttctt gtttactggt atgcttcaag cgactgggca aggtcgtggt
    36721 gctacaatta tggccatttt acaaggtgcg attatcattc cagtattatt tattatgaat
    36781 gctttgtttg gactaacagg tgtcatttgg tcattattaa ttgctgagtc actttgtgct
    36841 ttagcagcaa tgttaatcgt ttatttatta cgtgatcgtt tgacagttga tacatctgaa
    36901 ttaatagaag gttaaatatt tcgtacactt ctggctgagt atatttcggt cggaagggta
    36961 tttttcgaaa aaaataaata tatgatacga ttatgaaaaa ataaagtgag attggcatat
    37021 gtacaaatct aaaatactgt tgaaatatat ttttagtgaa gaatcagaag ttaaagattt
    37081 aactgaagaa aaatataatc aagattacga agcattaaca tttagcttta aagaggaaac
    37141 atatcaaagt aggttagcta agaaaacacc gactaaagca gggtattttg ttacatgttg
    37201 gacgaaagac gagaacaatt gtaatcaacc atactcgaaa gaggcatttg cagattactt
    37261 aatgattata gttattgatg aagaattaag cggttatttt ttatttccta gggaattatt
    37321 ggtagaaaaa ggtatcttaa ctacatttga acataaaggt aagatggctt ttagagttta
    37381 tcctaagtgg tgtaatcaat tgaataaaac agcagggcaa acacaaaagt ggcaatgtaa
    37441 atattttttt gaatactaat aaaaagtcat atggttgaac ttataagaga tgaatatatc
    37501 atctttcgat aagataacca tatgacttta ttttttatca tttaatgatg aacggtttct
    37561 tgtcctactt tattccaagt gaggataaag ctcaacattg caaacacact gattgctgtt
    37621 aataaaataa aaccgacatc ccatccgaat ttatcaacta cagcacctaa gacgatgttg
    37681 gccattacag caccaaacag ataaccaaat aatcctgtta atccagctgc tgtgccagct
    37741 gcttttttag gtacataatc taatgcttgt aaaccaatta acataactgg tccatatatt
    37801 aagaaaccaa tggcaattaa tgagacattg tctaaccaag cattgcctgg aggatttaac
    37861 caataaatta atacaaatac tgtgacacct aacataaaga agaaacctgc aggtccacga
    37921 cgacctttga ataatttatc agaaatgtaa ccacataata atgtaccagg aattccagcc
    37981 cattcgtata agaagtatgc ccaacctgat gcttttaagt cgaaatgttt ttcttcactt
    38041 aagtagactg gcgcccaatc aagtacacca taacgcacga aataaacaaa tatatttgca
    38101 aaggcaattg cccataccca tttattgttc agtacatatt taaataaaat ttcttttgta
    38161 gttaattctg tttctaatgt tttcttatcg cttgtagcaa agtcgttttt ataaatttcg
    38221 attggaggta aaccttgaga ttgaggtgtg tctctaatca atacgtatga aattgcggca
    38281 atgataagtg ctaagagtgc agggtaaatg aatacacctt cgaaaccttt taaataacca
    38341 aagttgataa atgctgttgt tgtaataccc caagcagcaa taggtgccat aatacctcca
    38401 ccaacattat gcgcaacgtt ccaaagggca gtcttacttc cgcgttcact tacactaaac
    38461 cagtgaacga gaacacggcc tgaaggtggc cagcccatac cttgaaacca tccatttaag
    38521 aataatagga caaacataat accgatacct gatgtaaaga acggtacaaa tcccattaac
    38581 aaattgacga tagcagtgag tgctaatcca agaactaaga atatccgagc attgctccga
    38641 tcacttacag tacccataaa gaacttacta aatccatatg cgatggaaac agcagaaagt
    38701 gcaaaaccta gttccgcttt tgtaaaacct tgctcttgca atgctggcat cgctaatgaa
    38761 aagtttttac gtaataaata gtacccagcg taaccgatga aaataccaag aaatacttgg
    38821 agacgtaatc gtttataggt atcatctatc tgattttctg gcaaaggctt aatatgcttt
    38881 gcaggtttaa gaaaattcat aaaatcctcc ttaatatgta tttatatgca ttttgtgcga
    38941 taaacttata ttagacatgt atgaaagcgt tgtcaatata cttttgtgaa atcttgcata
    39001 tttagttatt gaagtatttt ataaacattt agaaaaaata aattgctaca cataaattta
    39061 taattatgca attattatgt cgttatacat actagctgtg tatctacgaa tgagtacaaa
    39121 catattttta tttgcagaaa aggggtaaat ggcatataac tatctttttt atgtaagttg
    39181 gtataaaatt tatactaata ggagggatag tatgaatata gtagggcatc atcacatatc
    39241 catgtataca aaagatgcaa aacgtaataa ggatttttac acaaatgtcc ttggattacg
    39301 attagttgaa aagtctgtta atcaagacaa tccttcaatg tatcatttgt tttatgggga
    39361 cgaagtaggt acagccggaa caattttaag cttttttgaa attccccatg cgggtcataa
    39421 gcagccaggt actgaaacga tttatcgatt ttctttatta gtaccaaatc aagcggcact
    39481 tcattatttt gaaaaacgcc ttgataataa tggtattacg tctgaacgtt tgtactatct
    39541 tggacaagaa ggtgttgtct ttaaagatga agacgactta gaaatcatat tgcttgttaa
    39601 tgatagtttt gaagtaccac atcaatggca acataacgct tatagtgaaa tacctcaagc
    39661 atatcaaatt ttaggaatag ggccagtcga attaagagtt agaaatgcag cgcgtacggt
    39721 agaatttttg gaaaatgtct taggttatcg caaaagagat aataaatcat tcgatgtgct
    39781 gacattagca ccacaaggtt tatattcgga ttttgtagtt attgagcaac agggacaacg
    39841 tgaaagacct ggacgaggtt atatccatca tattgcaatt aatacaccac aaatgagtga
    39901 cttagatgca atttacaaga aattacaaca acaaacacaa agtaattcag gtataattga
    39961 tcgctatttc tttaaatcat tatactatcg ccataattca attatgtatg aatttgcgac
    40021 tgaagcgcct ggatttacta ttgatacacc tcttgaacaa ttaggaagtc aattgaactt
    40081 gcctgacttt ttagaagcag aacgtgaaca aattgaaagt aagttacacg aaatataaag
    40141 gagaatgttt aatggccaaa ttagaaatga ataaaaatac gcctcttgag tttggtttgt
    40201 attccttagg tgatcattta ttgaatccat ttaaaggtga aaaagttagt tatgagcaac
    40261 gtattaatga aattattgaa gcaagtaaat tagcagatga aacaggtatt gatgtttttg
    40321 cagttggtga aagtcaccag gagcatttta caacacaggc acatacggtt gtgttaggtg
    40381 caattgccca agcgacaaag catattaaag tttcaagttc ttcaacgatt attagtgcaa
    40441 cagatcctgt aagagtattt gaagacttcg cgacattaga tttgatttct catggtagag
    40501 ccgaaattgt agctggcaga gcatcaagaa caggtatttt tgacttgttt ggctatgatt
    40561 taaaagacta tgatgaattg tttgaagaaa aattaggttt acttttagag ttaaataaaa
    40621 ctgagcgtat tacttggtct ggaaaatatc gtccagaact tagaaatatg aaaatattcc
    40681 caagaccaat cgataatata ttgccaatat ggcgtgctgt tggtggtcca cctgcaagtg
    40741 ctattaaagc gggaaaacaa ggtgtgccaa tgatgattac aacccttggt ggcccagcaa
    40801 tgaactttaa aggttctata gatgcttatc gtcaagcagc aactgaagca ggtttcgatg
    40861 cttcgcataa gtctttacca gtaagtacag cgagtctgtt ttatacagct gaaacaactc
    40921 aggatgctat gagagaattt tatccacatt tgaatacagg gatgtcattt attcgtggtg
    40981 ttggttatcc gaaacagcaa tttgctaatt cgtcagatta tcgagaagcg ctaatggttg
    41041 gaagcccgca acaaattatt gaaaagatat tgtatcaaca cgagttgtat ggtcatcaac
    41101 gttttatggc acagcttgat tttggcggtg tgccatttga aaatgttatg aagaatattg
    41161 agttaattgg caacgaaatt ataccggcga ttaaaaagca tttatcaaaa taggaggggc
    41221 gtcatcatga atattgtatt attgtcaggt tccacagtag gttctaaaac gagaattgct
    41281 atggatgatt taaaaaatga actagaagtc atcaatgagg gacatcaaat agagttgatg
    41341 gatttacgag aacttgaatt agaatttagc gttggaaaga attatctaga tactacagga
    41401 gatgtatata aattaacgac gtcgttaatg caggctgatg tgatttttat tggttttcca
    41461 atttttcaag cttccatccc tggtgctttg aaaaatgtgt ttgatctact tccagtcaat
    41521 gcttttcgtg acaaggtaat aggacttgta gcgacagcag gttctagtaa acattattta
    41581 attcctgaaa tgcatttaaa accaatattg agttacatga aagcacatac gatgcaaacg
    41641 tatgtattta ttgaagagaa agatttttca aatcaacaaa ttgtcaatga tgatgttgta
    41701 tttcggttaa aagcgttggc acaattcaca atgcgaactg ccaaagtaca acaacaagtg
    41761 tttgaagaag aaaacaacca atacgacttt taaagtataa aaataagacg ctcggcacac
    41821 taaatttgta tgtgtttgag cgtcttttat attaactata tagccagtga acgacgataa
    41881 aggcaagtga tgacaagcat attgaggtaa taatgattgt cataagcggt ttaagtgcac
    41941 gatttttaag atctttaaat gcaacattta accctaaagc aaccatggcc attaataagc
    42001 aaattgttga tatagtattt aaaatattta acaatactga tggaatagtt acatatgtat
    42061 tcactaaggc cataatgaca aatccaatta aaaagtatgg aatgcttatt cgacccttgc
    42121 tagatgattc tgatgaacgg aaacgcataa ttaaaataag tacgatggtt aatggaatca
    42181 gtaagaatac tctaccaagt ttaccaagaa gtgcaatttt aagtgcatca ctaccaccaa
    42241 agccaccagc taagacaacg tgcgcaattt catgaagact aacaccagac caagcgccat
    42301 aaacatttgt cgtcattgaa aagatagcgt agatagctgt atatataagt gagaatatcg
    42361 taccaatcaa tgcgatgata ccgatactaa tagctgtatc cttttcacgt gatttgaata
    42421 ttggagcgac tgcggcaata gcggcagcac cacaaacgcc tgtgccgaca cctagtaata
    42481 atgcgatgtt tttgtcacca tgcaacagtt tgttgacaaa gagcatcatt acaatactga
    42541 aaataacgac acctacatcg atggctaata gtttactacc ttgaccgata atatcgaata
    42601 tattgagttt aagtccatat aggatgattg caaatcttaa taaatattta gatgaaaacg
    42661 taatacctga gctatattgt tcaggatatc ctctaaagtg acgatataga atagcgatta
    42721 atatcgcgat agttaatgcg ccaaccttat ctaagattgg caatttagct gctaaaaagc
    42781 taaataatgc gactataaat gttaatgata gtccaatcat aaaatgctta tttttcaatg
    42841 atgccatgag cagtgcctcc tttaatagca ttttagcact gttttgtcgt atttttaaat
    42901 ataaatttgg aatggttaat aaagtagtga ttaaattaag ttgtgtgata ggtatcaagg
    42961 acatcaacca aagtaatagg cactacaacg cttattggcg gggccccaac aaagaagctg
    43021 acgaaaagtc agcttacaat aatgtgcaag ttggggatgg gccccaacat agagaaattg
    43081 ggtccgtaat ttctacagac aatgcaagtt ggcggggccc caacaaattt aagatacaat
    43141 gcgtaatatt aatatgttat tattatgata atttacagaa ttatatgaaa aatgaatgag
    43201 gatgtgatgg tatgtttgga atgaaagtga atgaacaaat aacattaaaa attttagaag
    43261 ctcatgacac agaagcgctt ttcaatttag tcaatcgttc aagaaattca cttagggaat
    43321 ggttaccttg ggtagatgca actgagcaac catcagatac gcgtgcattt attaaaagag
    43381 gacttttgca atttgctgat ggtaatggat ttcagtgtgg catttggtat gaaggaacgc
    43441 tagttggtgt catcggttta catgaaatta atcacatgca cagaaaaact tcattagggt
    43501 actatttaga taaacaattt gagggtcatg ggattatgac acaagcagtt gaggcattga
    43561 taaagtattg tttcgaagag cttgacttaa accgaattga gattagtgcc gcagttaata
    43621 atgaaaaaag ccgagctatt cctgaaaggc tgggatttac tagagaaggt atgttacgtg
    43681 acaatgaatt actaaatggt atttattcat cgagttacat ctatagttta ttaaaatcag
    43741 aatacgacca aaaatgacaa attagactta caaaagagtg atgacattta aaatggcatc
    43801 gctcttttat ttaatttttg aaaataaaag gttgttgaca gtattatttt ataacaatat
    43861 aatgattttg ataattatta tcaactagat aatgttcatg ggaggatgcc ttaaaatcat
    43921 cattttaaga gccacgtatt atcttggcat ttagggagtg tgagatagta cgaatgaggg
    43981 catgtctatg gggataatag aatttctata atgaggtgtc aaaatgaaaa agttaacaac
    44041 gctattatta gcatcaacgt tattaattgc tgcatgtggg aacgacgata gtaagaagga
    44101 tgattcaaag acatcgaaaa aagatgatgg tgttaaagca gaattaaaac aagcaacaaa
    44161 agcatatgat aaatatactg atgaacagtt aaatgaattt ttaaaaggta cagaaaaatt
    44221 tgttaaagcg attgaaaata atgatatggc ccaagcaaaa gcgttatatc caaaagttcg
    44281 tatgtattat gaacgctctg aaccagttgc agaagcattt ggagatttag atcctaaaat
    44341 tgatgcacgt cttgcagata tgaaagaaga gaaaaaggaa aaagaatggt caggatatca
    44401 taagattgaa aaagcattat acgaagataa gaaaattgat gatgtgacta aaaaagatgc
    44461 acaacaatta ttgaaagatg caaaagaatt gcatgccaaa gctgatacat tagatatcac
    44521 accaaaatta atgttacaag gttctgttga cctattaaat gaagttgcaa cttctaaaat
    44581 cacaggtgaa gaagaaattt attcacatac agatttatat gattttaaag cgaacgttga
    44641 aggcgcacaa aaaatttatg acttatttaa acctatttta gagaaaaaag ataaaaaatt
    44701 aagtgatgat attcaaatga acttcgataa agtgaatcaa ttattggata aatataaaga
    44761 taacaacggc ggttatgagt catttgaaaa agtatcgaag aaagaccgta aagcatttgc
    44821 ggatgctgtt aatgcattag gagagccact aagtaaaatg gctgtgatta ctgaatgaca
    44881 aattatgaac aagttaacga tagtacgcaa ttttcaagac gtacattttt gaaaatgtta
    44941 ggtattggcg gtgccggtgt tgcaattggc gcaagtggtg ttggtagcat gtggtctttc
    45001 aaatcaatgt tcaatacacc agaagatccg gaaaaagatg cgtatgaatt ttatggtaaa
    45061 gtgcaaccag gcattaccac acccacgcaa aaaacatgca atttcgttgc gttagatttg
    45121 aagtcaaaag atagagatgc aattaaggca atgtttaaaa agtggacggt tatggctgat
    45181 cgtatgatgg atggtgatac agttggcaag acgagtaaca atcctttaat gccaccagta
    45241 gataccggtg aatcgatagg attaggtgca agcaagttaa cgattacctt tgggattagt
    45301 aagtctttga tgaagaaaat tgggttatct agtaaaattc ccgatgcctt taaagattta
    45361 ccgcattttc cgaatgatca gttaatagac gattacagcg atggtgatat tatgattcaa
    45421 gcatgctcaa atgattcgca agtatccttt catgcggttc ataatttagt tcgtccattt
    45481 cgagatattg ttaaggtacg ttgggcgcaa tctggtttta tctctgctaa aggtaaggaa
    45541 acacctagaa atttaatggc atttaaagat ggaacaatta atcctagaaa gagtaatcaa
    45601 cttaaagatt atgtgtttat tgatgacgga tgggcgaaac atggaactta ttgtgttgtc
    45661 agacgtattc aaatacacat tgaaacgtgg gatcgtactg cactggaaga acaagaggct
    45721 acatttggtc ggaaacgaca tagtggtgcg ccgttaacag gtgggaaaga gtttgatgaa
    45781 attgacttaa aagcgaaaga tagtcatggc gagtatatta ttgataaaga tgcccatacg
    45841 agactagcga aagaagcaaa tacgtcaatt ttacgtagag cctttaatta tgttgatggt
    45901 acggatgacc gcacaggtaa cttcgaaaca ggcttgttgt tcattgcttt tcaaaaagcg
    45961 acaaaacaat ttatcgatat acaaaataat ttaggtagta atgataaatt aaatgaatat
    46021 attacacata gaggttctgc ttcattttta gtattaccag gtgttagtaa gggaggatac
    46081 cttggtgaaa cattatttga ctaaatttgt agcaatgcta ataactgctg ctatggtgtg
    46141 tagctttggg ttactgaaaa gtcaggcagc agaacaacaa agtattagtg atgtatatag
    46201 tgtgataacg gatgcgaaat ctgcactttc taataattcg atatcgaatg acaataagca
    46261 gaaagcaatt gagcaagtgg taagtgcagt taagaaatta tcgcttgaag ataatagtga
    46321 aggtaatgct gtcaaatcag atgtgagaaa gcttgaagat gcaaaagcga atgataatca
    46381 aaaagataca ctttcgcaat taacgaagtc attaattgct tatgaagaga aattggctag
    46441 taaagatgcg ggttctaaaa ttaaactatt gcaacagcaa gtcgatgcca aagatgctgc
    46501 gatgacaaaa gcgattaaag ataaaaataa agcggaatta gaatctttga acaatagttt
    46561 gaatcagatt tggacaagta atgaaacagt gattcgcaat tatgacgcaa atcaatatgg
    46621 acaaattgaa gtcgcattat tacaacttag aattgcaatt cataagtcac cattagatac
    46681 ggcaaaagtg tcacatgctt ggacaacttt taaatcaaat attgatcatg tcgataaaaa
    46741 aagtgatacg tctgcaaatg atcaatacca tgtatcacaa ttaaatgatg cgttagagaa
    46801 ggcgattaaa gctatcgacg acaatcaatt gtcggatgct gatgctgcgc ttacacattt
    46861 tatagaaatt tggccgtatg ttgaaggtca aattcaaact aaagacgggg ctttgtatac
    46921 gaaaattgaa gataaaatac catattatca aagtgtatta gacgaacata ataaatcgca
    46981 tgtcaaagat ggtttagtag atataaacaa tcaaattaaa gaggttgttg gccatagtta
    47041 tagctttgtc gatgtgatga ttatcttttt acgtgaagga ctagaagtgt tattaattgt
    47101 aatgacattg actaccatga cgcgtaaagt caaagataat aaggggactg caagtgtgat
    47161 tggtggtgca attgccggac ttgtactgag tattatctta gcaattacgt ttgtagaaac
    47221 tttagggaat agtggcattc ttcgtgaaag tatggaagcg ggattaggta tcgttgcggt
    47281 catattaatg tttatcgttg gtgtttggat gcacaaacgt tcaaatgcga aacgctggaa
    47341 tgatatgatt aaaaatatgt atgccaatgc gattagtaat ggtaatttgg tattgttagc
    47401 gacgattggt ttaatatctg tgttgcgtga aggtgttgag gttatcattt tctatatggg
    47461 gatgataggt gagctagcga caaaagattt tattattggt attgccttgg ccatagtgat
    47521 attaattgtc tttgcggtat tatttagatt tatcgtcaga ttgataccta tattttatat
    47581 atttagagta ttgtcgatct ttatttttat tatgggattc aaaatgcttg gcgtaagtat
    47641 tcaaaagtta caattattag gtgcgatgcc aagacatgtt attgaaggat tcccaacgat
    47701 taactggttg ggcttctatc caagttatga accattgata gcacaagctg cttatattat
    47761 ggtagttgct atcttaatct ttaaatttaa aaaataaaaa acaggccgag tgcctgtttt
    47821 tttgttgctg tattgcggat tatcgtagca ttgttgagat gtggatatcg ctgcatggtt
    47881 ggttctcgtt gtattgcaga tatcacggtt taatccgatt ctgtattcta attaacgcaa
    47941 gtgcagtatt gatataatct gaggtgctac attgttcttt tattggctat tgtgatgttg
    48001 ctgcattgtg agtatcacag cattaattcg tataaggtta atgtgttggc ggtttgcctc
    48061 ggcatgtgaa cttaacaatg aacatactga actcaaagag caatatgagt ggcaatgtaa
    48121 gtaatatatt taatgttaaa tcgggtggtg caatgatact tgccagcaca aagcaagcga
    48181 aataaatata ttttcgataa tgcttcaatg atgtgatatc tataagaccg aattttgcaa
    48241 gtcctatgaa taatattggc aattggaata aaatgccaaa agtgaaaagc caacggataa
    48301 gttcaactaa atacgcttta aagccaatga caggcgaaat gtttaaagtt aatgataatt
    48361 ttaacgcgaa ttgaatgatt attggaaagc caacataaaa tgcaaaagcg acgccagcac
    48421 agaataataa cacgctgaaa aaactatatt tataaataaa ttgacgttca ttattatgta
    48481 atccaggtgc aatgaatgcc cacaattgat aaaacatgac tggtgaaatg aaacaaaacg
    48541 cgatgaaaaa tataatcatc acgtatattt ggatcatttc tgtgaatgaa aatgcatgta
    48601 aggacacatg tgcacgggta atatacgtta tgaatggtgt catccaccaa aatgatgaaa
    48661 catatacgac gatgactgtg acgacgaacg acaatagtat tttaactaaa cgatgacgta
    48721 gctcgctaaa atgaactagt aaggtgtggt cagtgctatt gctctcgctg ttgtttcgat
    48781 tccttactgg gtgtgtcgtg agactctttg tctaaatctt ctgttgcaga tttaaattct
    48841 tttaaagtag aaccgatagc acgaccaaat tgtggtaatt ttttcggacc aaaaataatt
    48901 aaagcgataa tgctaatgac gacaagactt gttgggcctg tgatgcctaa aataaaagtg
    48961 ttagttatca tgataatcaa cctcactcat aagtagtata tagtatttac tttataccga
    49021 acgataatga ttatcaataa aattttataa aataattaaa atgttgctgt aaatacaaat
    49081 tactgaggta ttaattctga aataatagct tgttctttca agtcgatata agtacaagta
    49141 ccagcttgaa tatcgatatg ccatttataa atgccagctt cagccatttc atcacaaaat
    49201 gtttcgaaat ctgtttgtcc ttgttgatgt ctagttaata catcttgaac tattgttttg
    49261 tttgattttt gagcaacagg atgattactt ttcacagatg acgtaacgat atcatcttct
    49321 gattgatgta cgtatgttgc agtgccatct tgaatgttga cgatattgta agtcatcccc
    49381 atatctttaa aagctttgaa tagttttgga aagtcaacac cagtaaattg ttgatgtgct
    49441 tgttgaattg cagataatgt aaatgccata atagtctcct ttgaatggtt tgatttagtg
    49501 aaaatgcgtg catcatacta aaattagaat gctgttaatt atgcaggaag gtgtaacgaa
    49561 agtaaacaat tatgacttgt aggcgttgag gtgttgtttc aaaatgtcat acataggtgg
    49621 acaatcatat ttttttgtgt agatttgaca aatatagttg tcaaaaagac aaatatcatt
    49681 tacattagga ctaaggagtt gatgcgatgt gcgtaatcga ttgaaagagt tacgagcacg
    49741 agatggctta aatcaaacgc agcttgccaa actagctggt gtttcaagac aaaccatttc
    49801 gctaattgag cgaaacaatt ttatgccatc agtattaacg gcaataaaga ttgctcgcat
    49861 tttcaatgaa acggtggaaa cggtttttat tattgaggag gatgaagcat gaaaatacta
    49921 agatatatcg gatatctttt actgggtgga attgtagggg gtatcattgg tggaatttta
    49981 ggtaactttg atggattggg tattgagaac ttgacgtttg cgacttataa caatgtcgtt
    50041 gtaatatcga ttgttgcgac tatgatcatc atattggtag aagccattgt tttgatgaat
    50101 caaagacgtg cattgaagta taagcgactt gtagatgaag aggtagatat cgatgcaaca
    50161 gatcaatatg aattgcttgc gaatcgttat gttttaaatg gaagtatatt aagcgttata
    50221 cagacaatta ttgcctttgt agtgttacta atttttgtgg tagggcaagc tgaagcaaat
    50281 gcaatgctat tctttttaat accatttttt gctagtgcta ttttcaatac acaatttaca
    50341 ctgtttaata gaaaatttga tgacagaatg ccaaaaattg cagataagaa ttacactgaa
    50401 aagcgattgg aaatattgga tgaaggtgaa cgccatatag aattaattgc attatttaaa
    50461 acatatgcga tcaacttatc aatattgata ctagccatta tttttatagg gtcttattca
    50521 attgctacag gaattaatca aagctttagt ttgctactta tcattgctat tttcatatat
    50581 aacgccttta gctatttatt gaagagaaga cgtttttatt aaaattaaac aaagaggagc
    50641 atggatatga caacattgtt aaacgtagat cgtgtgaaca aacaatacaa agattcggat
    50701 tttaaattgc aagatgcatc tttaacgatt tctactaatg agacagttgg attaattggg
    50761 aaaaatggct caggtaaatc gacattaatt aatattctag taggcaatcg acataaagat
    50821 aacggtagta ttgcattttt tggagaagaa catgctgcgg atgatgtcga atataaagaa
    50881 cacataggtg ttgtgtttga tgatctgaga gtacctaata aattgactat taaagatatt
    50941 gataaagtat ttcaatctat ttatacgact tggaatagtc aaaaattctt tgatttaatc
    51001 aaatatttcg agttaccact acaaactaaa attaaaactt tttcaagagg gatgcgaatg
    51061 aagatagctt taacgattgc gctttctcat gatgtgaagt tattaatctt agatgaagca
    51121 actgcaggta tggatgtttc tggaagagaa gaagtaatgg aactattaga agattttgtc
    51181 gctcaaggtg gaggcatctt aatatcatcg catatttctg aagatataga acaattagcg
    51241 gataaattag tgtttatgaa agatggacga atgattttaa ctgaacagaa agatatactt
    51301 ttagcacaat atggaattgt tacgacagga gataaagatg ttgaaattcc taagcattta
    51361 atcattgctt ctagattgtc aaaggggaaa tatcaaattt tagttaaaga ttatgcagaa
    51421 attgaaaatg cagagccttt aaaacacatt gatgacgcta cgaaaatcat aatgcgaggt
    51481 gaagtataat gaaaggtatg ttcctaagta gtttttatgc aacgagaaag caaacatata
    51541 tttattttat agtcgctatc atagctgcgg gatactttgc agtatttaat ccgttgatga
    51601 gttcggcaat ggctggggtt atgttaatca cacccattac tgataatatt aaacatgaaa
    51661 aagactcaag atggatgtat tatgtatcta ctttaccggt taaacgtagt gattatatta
    51721 agtcatactt tgccttttat ttaatcttat tcggtgcaag tttaatgatt ggattagttg
    51781 tgactacgat cgtgacccaa agtgtgatga ttggtattat gtcaggttta atgagttttg
    51841 gtatcatagg ggcatactct atcattttcc cattgacatt taaatttggc gctgaaaact
    51901 ctaatgtcat tatgatagtt gcatctatcc tactactttt ttctttcgtg gtctttttct
    51961 ttatatatgg tatggttagt ggtgcatcgg cattagaatt tgaaaaaatt agcactgaag
    52021 gatggttagt tgtcatagta tatgcggtca ttggtatcgt tataacaagt gtttcttata
    52081 tattgtctat taaaattttt aacaaacaag aactataatc aatattcttg gtgtgaagct
    52141 agtcattgaa ataatattta gagcaggtga taaatcaata cgattatcat ctgctctttt
    52201 tggtgttgtg gaatgaaatg cgggatgata ggttgaggtg acatctctat atcatatcat
    52261 atcatttgtt tttagaagat taggttatgt gggaattgca tccttttata gtgaggatta
    52321 acgtgtatat atcattgagt atgttgctga aatttatttg cgtgtatcat ttgatgattg
    52381 tataggctaa cgatttcctt ggaaatattt aaaaacctcg atcatgtagc ataactgaat
    52441 ccaaaagtat aatgtgaagt tcgacacttt tggattcagt tcaaatactt tgaccgaggt
    52501 gaatactatt tattcatgtt tattacgtag acgttgattt ttaaaataaa tcagcatgat
    52561 gcagaaagtc gcaacggata ccgagataat cattacttgg tcatgcccct taaagataag
    52621 gctgatgata tatgatacta caagtatgcc tagtgaagaa gaaatatatt ttgcgtttgt
    52681 cagttcatta tggaaataag gcgtgattaa ccataatcca atatagaata ttaaaacact
    52741 gatatacatc atattaattt caaacaagtc atttagttta ttgttattac taaaaacaat
    52801 tgcagcatta atcacaccta aagcgatatt gattaataga tgcgtatacg ataaacggaa
    52861 accgatagat gacaatttat gattaatgta attttcagta atgatccaat atacaccgaa
    52921 aagactaatt aaaatcataa attggaatat ataaatgtaa ctaaaatgat caatgctaaa
    52981 tgatgacgaa gctaaaccaa ccagtacctc gccaaagata ataattgtta gtaacgaaaa
    53041 acgttctact aaatgcatca tattaacagg tgataataca agatatttct gaaatggaat
    53101 aagtcctgtc gctgcaatga atacgcctaa aaatccaggg atgtaatgga tactttgtgg
    53161 tagtactaat gatagaaatg ataaaaatga aatcacaaag gctacgctcg caaaagcttg
    53221 acatgtacgc ttatcgccat aatctaaccc tgtacgtata tgtaataaat actgtaatcc
    53281 gatacttaaa tacataattg ccacgcataa gaagaatggg aagaatgtct tttcaaagtc
    53341 cggatatagg ctgttagata ggaagaccat gatgaacata ttaaacatca taaacgagac
    53401 gtctttgaat gtaacttgac caaatcgatt tgtaaaaaat gtttgatgag accacattaa
    53461 ccataagaac aaactcatga cgatgtattt gaaaaataaa tcagctgaaa tggaaccgtt
    53521 ttgtgttgtt aaaatcacat gtgcaatttt ttgaatggca tagacgaaaa ttaaatcaaa
    53581 gaacaactca tggaatcctg cacgcttttc agctaaatgt tttggtgtta atgcattaac
    53641 cataaaattt taactccttt aagatgtgta attaatttac taagtatact atttattttt
    53701 tctagtgaat aggggcagat ttggcgatga agtggaagga gaggtgactg caaggtaatt
    53761 gcggaattaa caatcatcag cgatttaata tttgattgga gacgtcatgg taataaaaaa
    53821 ttgatgagaa attgatggtg aaaccagctg tgaatagcga tgcaatgata gatagaattt
    53881 aattagagtc attacgcgaa atgattaatg ataatttgtg gtaaatcaaa gcataatttt
    53941 gtactataga tgaggatgat agagcatatt taagagtgtg aaatgttaaa gtgaaaccgt
    54001 ttacgtttcc gattgcccaa acaaattaca tcattgtata atatgatttg ttaaatgcat
    54061 aacaagaatg aaaatgtaac atacgtagca attggtttca taaattggat gttagtggcg
    54121 tattggttca ttagacgtat tagtaataaa attgtatata tcataaggag atgaatatga
    54181 catgacgaga gtcgtattag cagcagcata caggacacct attggcgttt ttggaggtgc
    54241 gtttaaagac gtgccagcct atgatttagg tgcgacttta atagaacata ttattaaaga
    54301 gacgggtttg aatccaagtg agattgatga agttatcatc ggtaacgtac tacaagcagg
    54361 acaaggacaa aatccagcac gaattgctgc tatgaaaggt ggcttgccag aaacagtacc
    54421 tgcatttaca gtgaataaag tatgtggttc tgggttaaag tcgattcaat tagcatatca
    54481 atctattgtg actggtgaaa atgacatcgt gctagctggc ggtatggaga atatgtctca
    54541 gtcaccaatg cttgtcaaca acagtcgctt cggttttaaa atgggacatc aatcaatggt
    54601 tgatagcatg gtatatgatg gtttaacaga tgtatttaat caatatcata tgggtattac
    54661 tgctgaaaat ttagtagagc aatatggtat ttcaagagaa gaacaagata catttgctgt
    54721 aaactcacaa cataaagcag tatgtgcaca gcaaaatggt gaatttgata gtgaaatagt
    54781 tccagtatcg attcctcaac gtaaaggtga accaatctta gtcactaagg atgaaggtgt
    54841 acgtgaaaat gtatcagtcg aaaaattaag tcgcttaaga ccagctttca aaaaagacgg
    54901 gacagttaca gcaggtaatg catcaggaat caatgatggt gctgcgatga tgttagtcat
    54961 gtcagaagac aaagctaaag aattaaatat cgaaccattg gcagtgcttg atggctttgg
    55021 aagtcatggc gtagatcctt ctattatggg tattgcacca gttggcgctg tagaaaaggc
    55081 tttgaaacgt agtaaaaaag aattaagcga tattgatgta tttgaattaa atgaagcatt
    55141 tgcagcacaa ttattagctg ttgatcgtga attaaaatta cctcctgaaa aggtgaatgt
    55201 taaaggtggc gctattgcat taggacaccc tattggtgca tctggtgcta gagttttagt
    55261 gacattattg catcaactga atgatgaagt tgaaactggt ttaacatcat tgtgtattgg
    55321 tggcggtcaa gctatcgctg cagttgtatc aaagtataaa taataagaaa acaggttatc
    55381 acaacagtat taattacatg ttggcataac ctgtttttat ttgtttatgg atttattggg
    55441 taatattagt catttgatgg tttaattgca aatgctctaa cagggaaccc aggtgcatct
    55501 tttggtttag ggctgatagc gtaaatgatg gcgccacgag ttggtaattg atctaaatta
    55561 gttaataact cgacttggta tttatcctga ccaagaatat aacgttcgcc aactaaatca
    55621 ccatttttta caacgtccac agatgcatcg gtatcgaatg tttcatgacc aacagcttca
    55681 acacggcgtt cttcaattaa gtacttcaaa gcatctaatc cccaacccgg tgcatgttgt
    55741 tgtccgttcg catctttgtt ttcaaacttt tcaatattag gccaacgttt tgaccaatcg
    55801 gtacgaagtg caacaaaagt gccaggttca atagtaccat gctctttttc ccatgcttct
    55861 atatgcgcac gtgttacgat gaaatcattg ttgttcgcta cttctgttga aaagtctaat
    55921 acaattaacg gcaataccaa ttcttttaaa tcaatgtctt ctaaataacg tttgttctcg
    55981 acaaagtgga ttggtgcatc aatgtgagta ccatattgcg ttacaatatt ccaacgttgc
    56041 acatagaaac catgatcttt aaccgtgaat aaagttgaaa cttcaccttt ttcaaactca
    56101 ctaaaacgtg gtatttctgg atcaaatgta tgcgttaaat caacccaagt tgcttgtttt
    56161 aaagtattta attgttgcca taaaggatat tgtgtcataa aatcacccgt ttttagttta
    56221 ttatatgata aatgctgcga ttattcttgg cgtttagctt taacagcatt cacaagtaca
    56281 gtcaatgcat ctttaacttc ttcttctttt cgcgttttca aaccacagtc agggtttacc
    56341 cagaataatg agcggtcgat ttgttgtagt gaacgattga ttgctgtagt aatttcttct
    56401 tttgttggaa tacgtggact atgaatatca tatacaccta gaccgatacc taaatcataa
    56461 ttaatatctt caaagtcttt aattaaatca ccatggctac gagatgtttc aattgaaata
    56521 acatcagcat ctaagtcatg aatagcatga atgatttgac cgaattgaga ataacacata
    56581 tgtgtatgga tttgagtttc atcacgaact gaagacgttg caagtttaaa tgataaaaca
    56641 gcatctttaa gatattgttc gtgatattca gagcgtaatg gtaagccttc acgtaatgca
    56701 ggttcgtcaa cttggataac tttgattcct gcagcttcaa gtgctaatac ttcttcgttg
    56761 attgctaaag caatttgatc ttgaacgact ttacgtggta aatcaacacg ttcaaatgac
    56821 cagtttagaa ttgttacagg tccagttaac atacctttaa ctggtttatc tgttaagctt
    56881 tgtgcataaa ctgtttcatc aacagttaaa ggcgctgtcc attttacatc accataaatg
    56941 attggtggtt ttacggcgcg tgaaccatat gattgcaccc aaccgaattt agttactaag
    57001 aaaccttgta atttttctcc gaagaattca accatgtcat tacgttcaaa ttcaccgtga
    57061 actaatacat ctaagccgat gtcttcttga attttaatcc atcgagcaat ttcatttttt
    57121 aagaatgttt catatgcttc gtctgtaatg cgtttgttct tccaatctgc acggtatttt
    57181 cgaacttctc ggctttgtgg gaatgatcca atagttgttg ttggtaaatc cggtaagttc
    57241 aaacgttttt gttgttgttc aatacgttgc gcgaatggtg attgtcttga agtacgcacg
    57301 ctttcgaaat cataatctaa gtttttgaat gattgatttt ggaaacgctc ataacgtgct
    57361 tttaatttat catatttaac actatcgttt tgattcaata ggcgacgcaa tgcatctaat
    57421 tcgtctaatt tttcagttgc aaagcttaag ccttcgccaa cacttgtatc taatgtttca
    57481 tcatctaaag atactggaac atgtaataat gaagatgatg gttgaatgac aagctcatta
    57541 gtgtgtgcta acaatttgtc gattaagact tttttagctt caatatcact tgcccataca
    57601 ttacgaccat caataattcc agcgtataat gtttttgatt tatcaaaatc tcctgcttca
    57661 atttgtttaa ggttatagcc attatcatgg acaaagtcta aacctaaacc accaacaggt
    57721 aaagaactta agaatttaag atgtgcacgt tcaaagtatg tttgaatgac taatttttta
    57781 gcaacaccag ctttttcgaa atagtcataa gcttcacgtg taatattttc atagctttcg
    57841 ctgtcgtctg taactaagat tggctcatca acttgaatgt actcagcacc tgcatcaatt
    57901 aatgattcaa acacttcttt ataaagtggt aataacgttt taactttttc ttcaaaagtt
    57961 tggtgaccgc cttttgataa tttaacaaaa gtaatcggac caacaatgac agggtgagcg
    58021 ttaacgttta aagattgggc atatttaaag cgatctaata atacattgcg actcacttta
    58081 ggctcaacat tgtcccattc aggtacgatg taatgatagt tagtgttaaa ccattttata
    58141 agtgcacttg caacatggtc tttattaccg cgagcaatat caaataataa atcatcatca
    58201 atagttcttc cttggaaacg ttcagggatg atgttgaata ataatgacgt atctaatata
    58261 tggtcatata aagagaaatc accaactggg atgctatcta agtgatagta cttttgtaat
    58321 aataaatttt ctttatgtag atcagttaat gtttgatcta attcttcttt agaaatcttc
    58381 tttgcccaat aactttcgat ggcttttttc cattctcttt ttctacctaa tcttgggaat
    58441 cctaagtttg atgttttaat tgttgtcata atattgcctc cttgtgagca gtaatagatt
    58501 ttgagtatgc tgcaagttct aatgaatctt cgacattttg aaacggtgtg ataatgtata
    58561 aaccattaaa atattcatga acagtatcga ttaaatcctt tgaaagctta agacttagtt
    58621 ctcgtgtttt ggctttatca tctttaactg cttcaaattg ttgtaaaatt tcatctgaca
    58681 tcttgattcc tggcacttca ttatgcaaaa agagtgcgtt tttgtaactt gcgataggca
    58741 taatgcctat gaaaaatggt ttgttcaagt gcttagtggc atggtaaatt tcaatgattt
    58801 tctctttgct gtacacgggt tgtgttataa aataagacat tccgctttct atctttttct
    58861 ctaatctttt gacggcacca tctaatttac gaacattagg gttaaaggcg ccagcgatgt
    58921 tgaagtgtgt acgtttcttc agcgcatcac cgtcagtgtt aataccttga ttaaatctta
    58981 gagcgagttc agttaatcct ttagaattaa catcatagac attggttgca cctggtaagt
    59041 gaccaacttt tgaaggatca ccagttatgg ctaatatttc gttaacgcca atgagcgata
    59101 atccaagtaa atgggactgc aagccgatta agtttcggtc tcgacatgta atatgtacga
    59161 gtggttcaat attgtaatat tgcttaatta agctagcagc agcaatattg ctaattctga
    59221 cagttgccaa tgaattatct gcgagtgtta ccgcatctac attagcttta tcaagtttag
    59281 cgatattttc aaaaaatcta tccgtgtcta aatgtttcgg tgtatccaat tcgataataa
    59341 cggttggacg ttcttgaacc ttagatgtta atgattgtct aactttattt tgagatggat
    59401 tgaaaagtgc tttcgttggt atcggaataa cttttttgtc attaacaggt ttaagtgtct
    59461 gaatagattc tttaataaat ttgatgtgct ctggcgttgt accacagcaa ccaccaatta
    59521 aacgaacacc ttcgcgaatt agattttgag caacttgacc gaaatattgt gcattgtcac
    59581 tatacttaaa ttcactattt tcaatatcta ataagctggc atttggataa caagataaga
    59641 atgcgtgctc tggtaattca atatgtgtga aagactcttg catatggtgc ggaccatgat
    59701 gacaattgag tcccacgatg tttgcaccac attgaacgag ttgttttaat ccttcattga
    59761 ttgcctgacc attaactaag taatttgtgt ttgaagcggt taattgagca atgattggaa
    59821 tgtcgtattt ctttctcgtt cgtgaaatga catttgttaa ctcttctagg tcgtaatacg
    59881 tttcgaaaag tagcgcgtca acgccttctt caattaaggt gtctatttga atttcagtat
    59941 gataaagaat agtttgtaag ctgatatcct cttgtttgat acctctaaac ccaccaactg
    60001 tgcctaatat atacgtatct ttatttgctg ctttttttgc gatgcgaacg gcggcttgat
    60061 gtattgcttt aactttatct tcaagaccga atcgttttaa cttttcaaaa tttgcaccat
    60121 aagtattggt ttgaatgaca tcagcaccgg cttcaatata tgaacgatgg atgcgttcaa
    60181 ctttatctgg atggctaaga ttatatgctt ctggacaggt gtctaatcct tcagagtata
    60241 aaatggttcc aatagcgcca tcagctacta aaacattatc tttcaattgt gtgaggaatt
    60301 gactcattga atgcctcctt taatgcgtat ttgatgtctg caatgagttc atcaggatct
    60361 tcgagaccaa cacttaatcg gaatagaccg aaagtgatac cacgttcttg tctcacttct
    60421 tcaggtagtg cagcgtgaga cattgttgct ggatgtgaaa ggatcgtttc aacaccaccc
    60481 agactcactg aaacgagtgg taatgtcagt gcatcgacaa attgttgtgc tttagactca
    60541 tcagctaaac gaaagccaat aacggcaccg ccatttttag cttgttctaa atgagcagta
    60601 gtgagtcccg gataataaac ttctgaaatt tcatcttgct ttattaaaaa tgacacgatt
    60661 ttttgcgcgt tttcgacaga ttgtttaaat ctgattggaa atgtttttaa atgtttagca
    60721 agtgtccagc tatcttgagc agataacata ttgcctgtac cattttgtat taaataaaga
    60781 gcttcactaa ttgcctcatt attagtaatg acagcaccag caattaaatc gctatgtcca
    60841 cttaaaaatt ttgtagcact atgaatgaca atatcagcgc caagtaataa aggtgattgg
    60901 cctaacggtg tcataaatgt attgtccaca gctaccagta gttcatgctt ttcggctatt
    60961 ttagaaacag ctttgatatc agtaatttta aaacagggat tcgatggtgt ttcgatataa
    61021 attaattttg tgtttgattg aatggcaccc tcgatttgtt cgagcttggt agtatctacg
    61081 gttgtaaatt caatattaaa tcgattcaaa atttgctcag tgaggcgaaa agtaccgcca
    61141 tatacatcat cgggtaagat gacatgatca ccagatttga aagtcaaaag tactgctgaa
    61201 atagcagcaa tacctgatgc aaaagcaaaa gcgaattttc cctgttctaa tcgtgctaac
    61261 ttctcttcta aaagttcacg gttagggttg ccacttcgtg cataatcata tttaacatcg
    61321 ccaccaagac ttgtttgatg gaatgttgaa gaatcataga gtggtgggtt agctgaatga
    61381 tattccacac ctctacgcca atcgaatatc acttctgtct cttttgaaag tgtcatacaa
    61441 tctctccaat ctgagcttta tctaatgctt ggatgatatc gcgttcgatg tcttcataat
    61501 tttcaacacc tagtgataag cggattaaat actcatcaat gccacgttta tctttttcag
    61561 catctggcat atcaacatgt gtttgggtgt aagggaaggt cactaatgtt tcagtacctc
    61621 ctaaactttc tgcaaaaata caaatgtcta aattttctaa taatttagcg acgctatagg
    61681 ccttgttaag tcttaaacta agcatgccag tttgcccgct atatagtact tcgtcaattg
    61741 cttgaagtga ctgacatttt ttagcaagtt ttctagcgtt tgattgcgca cgctcaatgc
    61801 gtaaatgcaa agttttaagt ccacgtaaca acaaataact atctattggt gaaagtgttg
    61861 cgccagtcat gttgtgaaaa tcaaacaact gttgcgcgag tgattcatct ttgacggtta
    61921 cgacacctgc tagtacatcg ttatgtccac caatatattt cgtagctgaa tgtaagacta
    61981 tatcagcacc ttctgctaat ggtgttgaaa gataaggtgt taaaaaagta ttgtcgataa
    62041 ttgacaataa gcctttagct ttacaaagtt gatagtacgg ctttacatca atagcaatca
    62101 tttgtgggtt agatattggt tcaatgaata atgcaactgt tttatcagtg atttcttttt
    62161 caacttgttc ataatctgta aaatcaacgt acttaaattt gatatcgtat tgttgctcgt
    62221 aaaattcaaa taatctaaat gtgccaccat ataaatcgaa tgaaactaaa atttcatcat
    62281 gaggtttaaa tagattacat attaattgaa tggctgacat tccacttgat gtagcgaatg
    62341 atgcaatacc atgctcaagt ttggcaaaac aggtttcaaa tgttgagcgt gtaggatttt
    62401 tagtacgtgt ataatcaaat cctgtcgatt gtcctagttt tggatgtttg taggcagtag
    62461 ataaatggat tggattcgct atagcaccgg ttgaatcatc agttaatgtg atttgggcta
    62521 actgtgtatc cttcatatta agaccctcct ataagaaaaa ataaaaagct tccgtccttc
    62581 gtacccgaat gaatcggata aaaaggacga aagcttatgt ttcgcggtac cacctttatt
    62641 tgttattcca tcgctgaaat aaccttattc agtacgcatt aaaagtaaat atgcttactg
    62701 aacaattatc acaattaaag tcagtaagta aggatatagt aatgtgctat cccatactta
    62761 ttaacaaaaa atcgtgcgta aagaatccag tacgccattt aacatcaatg ttaatactgt
    62821 atcgctataa cgggcgaacc cgtagacacc tcatattggc atcaacactc caaggccatt
    62881 ttcaaacacg ctttcaaaat cttctctcag ctactaaaga ctctctgtat aagcagggtg
    62941 tgttttactt tcctctttat tgtgtttacg tttcattaaa ctattataag atattaatta
    63001 gcttacagag taaaaaaaga tttgtcaaca attattcaga aaattttgat ttaaaagtta
    63061 atttgtttgt gaaattgtaa ttggtatctt gaagttgaaa aatgaattat tttttaaata
    63121 aagtgtggtt aatggttgtc tgactcattt agaatacata aaatatattt aactgttgtt
    63181 atcaaataaa aagtgatgtg agtgaattgt caaaaagtga agatcaacgt attactaaaa
    63241 caaaagatga acaaattaag caaatagata tatcggatat caaaccgaat ccgtatcagc
    63301 cccgaaaaac tttcgatgaa aatcatttaa atgatttggc agattcaatt aagcaatatg
    63361 gaattttgca accaattgtg cttagaaaaa cagttcaagg ttattacatt gtagttggtg
    63421 aaagaaggtt tagagcttcg aaaattgctg gtctaaaata cgtatcagcg attatcaaag
    63481 atttaacaga tgaagatatg atggaactgg cggtcatcga aaatttacaa cgagaagact
    63541 taaatgcgat tgaagaagct gaaagttatc aacgtttgat gacagatttg aaaattacac
    63601 aacaagaagt agcgaagcga ttgagtaagt cgcgcccgta tatagcgaat atgttgaggt
    63661 tattacattt gccgaaaaag attgctgaca tggtaaaaga tgggcgactg acaagtgcac
    63721 atggacgaac gttattggca attaaagatg aacaacaaat gcttaggtta gcgaaacggg
    63781 ttgttaaaga aaagtggagt gttagatatt tagaaaacca tgttaatgaa ttaaaaaatg
    63841 tttcgtcaaa gtcggaaaca gacaaagtag atataactaa gcctaaattt ataaagcaac
    63901 aagaacgaca gttgcgagaa cagtatggta ccaaagtaga tatatcaata aaaaaatcgg
    63961 ttggtaaaat ctcatttgag tttgattcac aagatgactt tgtgagaata attgaacaat
    64021 taaatcgtag gtatggtaaa tagttacaca attttatata ataactcttt gtgaatctat
    64081 agatatattg atagttatct atattctttg aagatgatgc gacttcagta ggttggaaga
    64141 atacaacaat attaataaaa ttatttgaga ctatatagaa gggagtaacg ctaattatgg
    64201 atcaagttat gagtattatt tcatcgctat tcgaaccatt aactaaaatt gaaacatatg
    64261 aaaatattgc aactaaaatc gctatgattg ttatttatat tatcgtagcc ctcatagtta
    64321 ttaaaatact gaataaaatg attgaacagg gatttaagat tcaaaataaa agtaaaaaga
    64381 gtaacaaaaa gcgctctaaa actttaatat ctcttgttca aaatgtagtg aagtatatcg
    64441 tttggtttat agttattacg acgattttaa gtaaatttgg cattagtgtt gaaggtgtta
    64501 ttgcaagtgc tggtgtcgta ggtttagcag taggttttgg tgcgcagacc attgttaaag
    64561 acgttattac tggatttttc attatatttg aaagccaatt tgatgtaggt gattatgtta
    64621 agataaacaa cggtggtaca actgtagcag agggaacagt taaatcaatt ggactccgtt
    64681 caacacgtat taatacaata tctggagaac ttacaatctt gccaaatagt agcatgggtg
    64741 aaataacgaa ttactcaatt acgaatggaa cagcaattgt taaaattcca gtatctgtag
    64801 atgaaaatat tgataatgtt gagaagaaat taaacaaatt atttacatct ctacgtagta
    64861 aatattattt atttgtaagt gatcctgttg tgattggtat tgatgccttt gaagatacta
    64921 gagtaatatt aagggtttca gcagaaacaa taccaggtga aggtttctct ggtgcgcgta
    64981 ttattcgtaa agaagtacaa aaaatgtttt tacaagaagg tatcaagaca ccacaaccaa
    65041 taatgacacc ttttaatcat agtgaaaacg gtgtttagta gtttataata catggaggtc
    65101 atatttaatg gcgtcaaaat atggaataaa tgatatagta gaaatgaaaa aacaacatgc
    65161 gtgtggaacc aatcgtttta aaattattag aatgggtgct gacattagaa ttaagtgtga
    65221 aaattgtcaa cgaagcatta tgattccacg tcaaacgttt gataaaaaac taaaaaaaat
    65281 catcgtatct caggatgata cacaaagata ggagaatgat tcatggcttt aacagcaggt
    65341 atcgttggct taccaaacgt tggtaaatca acattattta atgcaattac aaaggcgggt
    65401 gccttggcag caaactatcc gttcgcaact atagacccaa atgtgggtat tgtagaagtg
    65461 ccagatgcaa gactacttaa attagaagaa atggttcaac ctaaaaaaac attacctact
    65521 acatttgaat ttacagatat tgccggaatt gttaaaggtg cttctaaagg tgaaggttta
    65581 ggtaataaat tcttatcaca tattagagaa gtagatgcaa tttgtcaggt tgttcgtgct
    65641 tttgacgatg ataatgtaac acatgtagct ggtcgagttg atccaattga tgacatcgaa
    65701 gttatcaata tggaattagt acttgcagac ttagaatcag ttgaaaaacg cttacctaga
    65761 attgaaaaat tggcacgtca aaaagataag actgctgaaa tggaagtgcg tattttaaca
    65821 actattaaag aagctttaga aaatggtaaa cccgctcgta gtattgactt taatgaagaa
    65881 gaccaaaaat gggtgaatca agcgcaatta ctgacttcta aaaaaatgct ttatatcgct
    65941 aatgttggtg aagatgaaat tggtgatgat gataatgata aagtaaaagc gattcgtgaa
    66001 tatgcagcgc aagaagactc tgaagtgatt gttattagtg caaaaattga agaagaaatt
    66061 gctacattag atgatgaaga taaagaaatg ttcttagaag atttaggtat cgaagaacca
    66121 ggattagatc gattaattag aacaacttat gaattattag gattatcaac atattttact
    66181 gctggtgtgc aagaagtacg tgcttggaca tttaaacaag gtatgactgc acctcaatgt
    66241 gctggtatca ttcatactga ttttgaacgt ggatttatcc gtgccgaagt aacaagttat
    66301 gatgactatg tacaatatgg cggcgaaagt ggcgctaaag aagcgggcag acaacgatta
    66361 gaaggtaaag aatatattat gcaagatggc gatatcgttc atttcagatt taatgtataa
    66421 acgatagagt gaagttaatt aaatagtata tatgtagaag aggcggaatc aattgttcgc
    66481 ctcttttaat tatgcgtata atttattaaa agaatggaat gattttactc gcgtaaataa
    66541 tatcttgagt gctgaaaaat tgtttgcctt cgccagtata agcaggctct aaaacaagat
    66601 tagcctttgc acaataaagc cattcaggat gaatgccact attaagtatc tcttggaatt
    66661 cttgaaaatc tttagaccaa tcaatattta aattcattcc ttaccacctc acaaccatta
    66721 tagaacatgc gttcgctttt gtgaagtgta tttttaaaaa tatcatagaa aatttcaaat
    66781 gaattaatgt caaaaatgat atgaagagta gtttgaatta ttattgtaaa aagtaatggc
    66841 gcatgatata attctttatt gtgagtaatg aaaattattc cttgcttatc tgttttaaga
    66901 ttgataagcc gtatagacca caaggaggtg caaatataaa atgagaacat atgaagttat
    66961 gtacatcgta cgcccaaaca ttgaggaaga tgctaaaaaa gcgttagttg aacgtttcaa
    67021 cggtatctta gctactgaag gtgcagaagt tttagaagca aaagactggg gtaaacgtcg
    67081 cctagcttat gaaatcaatg atttcaaaga tggcttctac aacatcgtac gtgttaaatc
    67141 tgataacaac aaagctactg acgaattcca acgtctagct aaaatcagtg acgatatcat
    67201 tcgttacatg gttattcgtg aagacgaaga caagtaataa ttagaggggg cgtttaaatg
    67261 ctaaatagag ttgtattagt aggtcgttta acgaaagatc cggaatacag aaccactccc
    67321 tcaggtgtga gtgtagcgac attcactctt gcagtaaatc gtacgttcac gaatgctcaa
    67381 ggggagcgcg aagcagattt tattaactgt gttgttttta gaagacaagc agataatgta
    67441 aataactatt tatctaaagg tagtttagct ggtgtagatg gtcgcttaca atcccgtaat
    67501 tatgaaaatc aagaaggtcg tcgtgtgttt gttactgaag ttgtgtgtga tagcgttcaa
    67561 ttccttgaac ctaaaaatgc gcaacaaaat ggtggccaac gtcaacaaaa tgaattccaa
    67621 gattacggtc aaggattcgg tggtcaacaa tcaggacaaa acaattcgta caataattca
    67681 tcaaacacga aacaatctga taatccattt gcaaatgcaa acggaccgat tgatataagt
    67741 gatgatgact taccattcta ataaaaatta acgaaattaa agcgaaaaaa ttatcaaagg
    67801 aggcacacaa tcatggcagg tggaccaaga agaggcggac gtcgtcgtaa aaaagtatgc
    67861 tatttcacag caaatggtat tacacatatc gactacaaag acactgaatt attaaaacgt
    67921 tttatctcag aacgcggtaa aattttacca cgtcgtgtaa ctggtacttc agctaaatat
    67981 caacgtatgt tgactacagc tatcaaacgt tctcgtcata tggcattatt accatatgtt
    68041 aaagaagaac aataatatat aacgtataac aaaacccttt agcaatcagg ctagagggtt
    68101 gtttttgtgt ttatttttat aaaaatttcg caattttttc gcagagtgtg aaaagtttga
    68161 tgattaaaat taaaaaaacg gacaaataat tgtccgtctt tgcgagatat taatctcata
    68221 taatagtttg gtgaggactc gcctctatat atgtaaatga taactgatta ttatttgtac
    68281 gtcaatctaa ttgattagct tatttttaat ttcattatct actaatttca tactatcaaa
    68341 atcgagtttc attctaccag aaggatcttc agcgttaatt tttaaaattc ttaatttgct
    68401 aatagttact acattctgtg tgcaggcaaa tgtattttta tcaaattttt tatatttatt
    68461 aataacttct ctaaggttat taacttttga ttttctatcg tttacatcaa ttagcaaata
    68521 attaaacaaa gcagaaaaat ttttcgggtc attgtataaa ttaaatgatt ctactatgtt
    68581 tttactttta ttaattactt ctctttctgt agggaagcgt gttttaatt
//
LOCUS       DAPDIM010000007        59896 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000007 DAPDIM010000000
VERSION     DAPDIM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 59896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59896
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.007"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            364..855
                     /gene="lspA"
                     /locus_tag="RFE25_000486"
     CDS             364..855
                     /gene="lspA"
                     /locus_tag="RFE25_000486"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDU2815586.1"
                     /translation="MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHF
                     LNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLLFAG
                     ALGNFIDRILTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEK
                     EVK"
     gene            855..1772
                     /locus_tag="RFE25_000487"
     CDS             855..1772
                     /locus_tag="RFE25_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDU2815587.1"
                     /translation="METYEFNITDKEQTGMRVDKLLPELNNDWSRNQIQDWIKAGLVV
                     ANDKVVKSNYKVKLNDHIVVTEKEVVEADILPENLNLDIYYEDDDVAVVYKPKGMVVH
                     PSPGHYTNTLVNGLMYQIKNLSGINGEIRPGIVHRIDMDTSGLLMVAKNDIAHRGLVE
                     QLMDKSVKRKYIALVHGNIPHDYGTIDAPIGRNKNDRQSMAVVDDGKEAVTHFNVLEH
                     FKDYTLVECQLETGRTHQIRVHMKYIGFPLVGDPKYGPKKTLDIGGQALHAGLIGFEH
                     PVTGEYIERHAELPQDFEDLLDTIRKRDA"
     gene            2172..2699
                     /gene="pyrR"
                     /locus_tag="RFE25_000488"
     CDS             2172..2699
                     /gene="pyrR"
                     /locus_tag="RFE25_000488"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDU2815588.1"
                     /translation="MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEY
                     LANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIID
                     DVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVS
                     VYLEEMDQRNAVIIK"
     gene            2917..4224
                     /locus_tag="RFE25_000489"
     CDS             2917..4224
                     /locus_tag="RFE25_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDU2815589.1"
                     /translation="MQNDEMFERTVKPVLDVNEKPQPAQWAFLSLQHLFAMFGATVLV
                     PFLTGLPISAALLASGIGTLLYILITKAQIPAFLGSSFAFITPIITGLSTHSLGDMLV
                     ALFMSGVMYVIIGILIKLSGTAWLMKLLPPVVVGPVIMVIGLSLAPTAVNMAMYENPG
                     DMKGYNISFLIVAMITLLVTIVVQGFFKGFLSLIPLLVGIIVGYVVAIFMGIVKFDAI
                     MSAKWIDFPHIYLPFKDYVPSFHLGLVLVMIPIVFVTVSEHIGHQMVLNKIVGRNFFE
                     KPGLDKSIIGDGVSTMFASIIGGPPSTTYGENIGVLAITRIYSIYVIGGAAVIAIVLA
                     FIGKFTALISSIPTPVMGGVSILLFGIIAASGLRMLVESKVDFANNRNLVIASVILVV
                     GIGNLVFNLKEIGINLQIEGMALAALSGIILNLILPKEKKQNN"
     gene            4252..5133
                     /locus_tag="RFE25_000490"
     CDS             4252..5133
                     /locus_tag="RFE25_000490"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HDU2815590.1"
                     /translation="MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLF
                     FENSTRTKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIRHP
                     FNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNVLICGDIKNSR
                     VARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVIETVDIVMLLRIQHERHGL
                     AEETRFAADDYHQKHGLNEVRYNKLQEHAIVMHPAPVNRGVEIQSDLVEASKSRIFKQ
                     MENGVYLRMAVIDELLK"
     gene            5151..6425
                     /locus_tag="RFE25_000491"
     CDS             5151..6425
                     /locus_tag="RFE25_000491"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDU2815591.1"
                     /translation="MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIID
                     AKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEH
                     FEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMM
                     YEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLL
                     AEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMN
                     PPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLY
                     THFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFL
                     SKADNTPFIGYKVYGNPILTMVEGEVKFEGDK"
     gene            6427..7527
                     /gene="carA"
                     /locus_tag="RFE25_000492"
     CDS             6427..7527
                     /gene="carA"
                     /locus_tag="RFE25_000492"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDU2815592.1"
                     /translation="MQSKRYLVLEDGSFYEGYRLGSDNLTVGEIVFNTAMTGYQETIS
                     DPSYTGQIITFTYPLIGNYGINRDDFESLVPTLNGIVVKEASAHPSNFRQQKTLHDVL
                     ELHQIPGIAGVDTRSITRKIRQHGVLKAGFTDRKEDIDQLVKHLQQVELPKNEVEIVS
                     TKTPYVSTGKDLSVVLVDFGKKQNIVRELNVRGCNVTVVPYTTTAEEILAMAPDGVML
                     SNGPGNPEVVECAIPMIQGILGKIPFFGICLGHQLFALSQGASSFKMKFGHRGANHPV
                     KNLETGKVDITSQNHGYAIDIDSLKSTDLEVTHLALNDGTVEGLKHKTLPAFSVQYHP
                     EANPGPSDSNYLFDDFVAMMTNFKEKERHINA"
     gene            7520..10693
                     /gene="carB"
                     /locus_tag="RFE25_000493"
     CDS             7520..10693
                     /gene="carB"
                     /locus_tag="RFE25_000493"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDU2815593.1"
                     /translation="MPKRNDIKTILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRV
                     ILVNSNPATIMTDKEIADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAIQL
                     HESGVLQDNNVQLLGTELTSIQQAEDREMFRTLMNDLNVPVPESDIVNTVEQAFKFKE
                     QVGYPLIVRPAFTMGGTGGGICHNDEELHEIVSNGLHYSPATQCLLEKSIAGFKEIEY
                     EVMRDKNDNAIVVCNMENIDPVGIHTGDSIVVAPSQTLSDVEYQMLRDVSLKVIRALG
                     IEGGCNVQLALDPHSFDYYIIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     LNPITGTSYAAFEPTLDYVISKIPRFPFDKFEKGERELGTQMKATGEVMAIGRTYEES
                     LLKAIRSLEYGVHHLGLPNGESFDLDYIKERISHQDDERLFFIGEAIRRGTTLEEIHN
                     MTQIDYFFLHKFQNIIDIEHQLKEHQGDLEYLKYAKDYGFSDKTIAHRFNMTEEEVYQ
                     LRMENDIKPVYKMVDTCAAEFESSTPYYYGTYETENESIVTDKEKILVLGSGPIRIGQ
                     GVEFDYATVHAVWAIQKAGYEAIIVNNNPETVSTDFSISDKLYFEPLTEEDVMNIINL
                     EKPKGVVVQFGGQTAINLADKLAKHGVKILGTSLENLNRAEDRKEFEALLRKINVPQP
                     QGKSATSPEEALANAAEIGYPVVVRPSYVLGGRAMEIVDNDKELENYMTQAVKASPEH
                     PVLVDRYLTGKEIEVDAICDGETVIIPGIMEHIERAGVHSGDSIAVYPPQTLTEDELA
                     TLEDYTIKLAKGLNIIGLINIQFVIAHDGVYVLEVNPRSSRTVPFLSKITDIPMAQLA
                     MRAIIGEKLTDMGYQEGVQPYAEGVFVKAPVFSFNKLKNVDITLGPEMKSTGEVMGKD
                     TTLEKALFKGLTGSGVEVKDHGTVLMTVSDKDKEEVVKLAQRLNEVGYKILATSGTAN
                     KLAEYDIPAEVVGKIGGENDLLTRIQNGDVQIVINTMTKGKEVERDGFQIRRTTVENG
                     IPCLTSLDTANALTNVIESMTFTMRQM"
     gene            10803..11495
                     /gene="pyrF"
                     /locus_tag="RFE25_000494"
     CDS             10803..11495
                     /gene="pyrF"
                     /locus_tag="RFE25_000494"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDU2815594.1"
                     /translation="MKDLPIIALDFESKEKVNQFLDLFDESLFVKVGMELFYQEGPQL
                     INEIKERGHDVFLDLKLHDIPNTVGKAMEGLAKLNVDLVNVHAAGGVKMMSEAIKGLR
                     KHNQHTKIIAVTQLTSTTEDMLRHEQNIQTSIEEAVLNYAKLANAAGLDGVVCSPLES
                     RMLTEKLGTSFLKVTPGIRPKGASQDDQHRITTPEEARQLGSTHIVVGRPITQSDNPV
                     ESYHKIKESWLV"
     gene            11495..12106
                     /locus_tag="RFE25_000495"
     CDS             11495..12106
                     /locus_tag="RFE25_000495"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDU2815595.1"
                     /translation="MAKEIAKSLLDIEAVTLSPNDLYTWSSGIKSPIYCDNRVTLGYP
                     LVRGAIRDGLINLIKEHFPEVEVISGTATAGIPHAAFIAEKLKLPMNYVRSSNKSHGK
                     QNQIEGAKSEGKKVVVIEDLISTGGSSVTAVEALKQAGAEVLGVVAIFTYGLKKADDT
                     FSNIQLPFYTLSDYNELIEVAENEGKISSEDIQTLVEWRDNLA"
     gene            12136..12348
                     /locus_tag="RFE25_000496"
     CDS             12136..12348
                     /locus_tag="RFE25_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815596.1"
                     /translation="MNDKTSNDLYGKIKHCNEFINHSNDSNLSSSHDVDESSTKQKHI
                     KNKTTIDHNDDLFKHVKDILRKQGQI"
     gene            12785..13186
                     /locus_tag="RFE25_000497"
     CDS             12785..13186
                     /locus_tag="RFE25_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDU2815597.1"
                     /translation="MDIPKITTFLMFNNKAEEAVKLYTSLFEDSEIITMAKYGENGPG
                     DHGTVQHSIFTLNGQVFMAIDANSGTELPMNPAISLFVTVKDTIEMERLFNGLKDEGA
                     ILMPKTNMPPYREFAWVQDKFGVSFQLALPE"
     gene            complement(13449..15146)
                     /locus_tag="RFE25_000498"
     CDS             complement(13449..15146)
                     /locus_tag="RFE25_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001575279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDU2815598.1"
                     /translation="MAYDGLFTKKMVESLQFLTTGRVHKINQPDNDTILMVVRQNRQN
                     HQLLLSIHPNFSRLQLTTKKYDNPFNPPMFARVFRKHLEGGIIESIKQIGNDRRIEID
                     IKSKDEIGDTIYRTVILEIMGKHSNLILVDENRKIIEGFKHLTPNTNHYRTVMPGFNY
                     EAPPTQHKINPYDITGAEVLKYIDFNAGNIAKQLLNQFEGFSPLITNEIVSRRQFMTS
                     STLPEAFDEVMAETKLPPTPIFHKNHETGKEDFYFIKLNQFNDDTVTYDSLNDLLDRF
                     YDARGERERVKQRANDLVRFVQQQLHKYQNKLAKLIEEYEQSKNKDTEQLYGELITAN
                     IYRIKQGDKEVTALNYYTNEEVVIPLNPTKSPSANAQYYYKQYNRMKTRERELQHQIQ
                     LTKDNIDYFSTIEQQLHHISVHDIDEIRDELAEQGFMKQRKNQTKKKKAQIQLQHYVS
                     TDGDDIYVGKNNKQNDYLTNKKAKKTHTWLHTKDIPGSHVVIFNDAPSDTTIKEAAML
                     AGYFSKAGNSGQIPVDYTLIKNVHKPSGAKPGFVTYDNQKTLYATPDYELIQKMKQL"
     gene            15421..16044
                     /gene="gmk"
                     /locus_tag="RFE25_000499"
     CDS             15421..16044
                     /gene="gmk"
                     /locus_tag="RFE25_000499"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDU2815599.1"
                     /translation="MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQ
                     MREGEVDGVDYFFKTRDAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFL
                     EIEVEGAKQVRKKFPDALFIFLAPPSLDHLRERLVGRGTESNEKIQSRINEARKEVEM
                     MNLYDYVVVNDEVELAKNRIQCIVEAEHLKRERVEAKYRKMILEAKK"
     gene            16044..16262
                     /locus_tag="RFE25_000500"
     CDS             16044..16262
                     /locus_tag="RFE25_000500"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDU2815600.1"
                     /translation="MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHS
                     FKPVGRALEEIADGKIRPVISSDYYGKE"
     gene            16478..17677
                     /gene="coaBC"
                     /locus_tag="RFE25_000501"
     CDS             16478..17677
                     /gene="coaBC"
                     /locus_tag="RFE25_000501"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDU2815601.1"
                     /translation="MKKILLAVTGGIAAYKAIDLTSKLTQSGYEVRVMLTNHAQKFVT
                     PLAFQAISRNAVYTDTFIEENPSEIQHIALGDWADAIIVAPATANTIAKLSVGIADDL
                     VTSTLLATETPKFIAPAMNVHMYENKRTQQNINILKEDGYHFIEPGSGFLACGYVAKG
                     RMEEPLQIVSVIDAHFQNSNRLANSSFQDKRALVTAGPTIEVIDPVRFVSNRSSGKMG
                     YAIAEALRNRGAIVTLVAGPTTLEDPKDIEVIHVQSAEEMFEQVTSRFDEQDIVVKAA
                     AVSDYTPVDVLEHKMKKQDGDLSVSFKRTKDILKYLGEHKTSQYLIGFAAETEDIENY
                     AQQKLRKKNADVIISNNVGDMSIGFSSDDNELTMHFKNNEKVNIKKGKKVVLAAQILD
                     ELETRWQ"
     gene            17677..20085
                     /gene="priA"
                     /locus_tag="RFE25_000502"
     CDS             17677..20085
                     /gene="priA"
                     /locus_tag="RFE25_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDU2815602.1"
                     /translation="MIAKVIVDVASKSVDYKFDYIIPEQLESVIQPGVRVIVPFGPRT
                     IQGYVMEVTAEPDAQLDVSKLKKIIEVKDIQPELTSELIALSEWMGSTHVIKRISMLE
                     VMLPSAIKAKYKKAFKMKDDIELPSALLQKFDKHGYYYYKDAQKNNDIQLLMKLLKDD
                     IVEEKTILTQNITKKTKRAVRVIEGYHPDEVLAKLEKVIKQYDLYAYLSEEQHKTIFL
                     TDIEDMGFSKSSLDGLIKKGYVEKYDAVVERDPFKDRVFEQESKQQLTEDQYKAYEAI
                     KAKIVSQEQETFLLHGVTGSGKTEVYLQTIEDVLSQGKQAMMLVPEIALTPQMVLRFK
                     RRFGDDVAVLHSGLSNGERYDEWQKIRDDRARVSVGARSSVFAPFKNLGLIIIDEEHE
                     STYKQEDYPRYHAREIAQWRSEYHHCPVILGSATPCLESYARAEKDVYHLLSLPNRVN
                     QQALPEIDIVDMREELSEGNRSMFSKDLREAIQLRLDRQEQVVLFLNRRGYASFMLCR
                     DCGYVPQCPNCDISLTYHKTTDLLKCHYCGYQETPPNQCPNCESEHIRQVGTGTQKVE
                     ELLQQEFEDARIIRMDVDTTSKKGAHEKLLTEFEKGNGDILLGTQMIAKGLDYPNITL
                     VGVLNADTMLNLPDFRASERTYQLLTQVAGRAGRHEKAGQVIIQTYNPDHYSILDVQK
                     NDYLTFYRQEMEYRKLGKYPPYYYLINFTISHKEMKKVMEASQHVHKILLQHLTEKAL
                     VLGPSPAALARINNEFRFQILVKYKSEPGLLQAIQFLDDYYHEKFIKEKLALKIDIDP
                     QMMM"
     gene            20591..21544
                     /locus_tag="RFE25_000503"
     CDS             20591..21544
                     /locus_tag="RFE25_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815603.1"
                     /translation="MKKTLGCLLLIMLLVVAGCSFGGNHKLSSKKSEESKQETVKKES
                     EEEKDPDLEKYEEIEKKMKGIKDAPSLDKLDPLMTEKSFTNSKGIQGWKDYKELMGKV
                     ELADYRFTKDSKGSSIKDVDAFFKGKKGIKRKVIETHDDVKQVDYWYVDPDGKKIGNS
                     NTPVFYAEIMTKYKDGKLVYASVEPGSYVIHKDDAIKYDDYSKLKKLSQLTKLDHPKP
                     VPYSVAQIKSFGVPLTSVSFMTHGSKDTKDEVLPALAYFTFSPKNYEDKSNPDPKVLN
                     LVHMDFLNASSDFGNAHFVVLSKYIKEYESNYETASDDSLK"
     gene            complement(21707..21910)
                     /locus_tag="RFE25_000504"
     CDS             complement(21707..21910)
                     /locus_tag="RFE25_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HDU2815604.1"
                     /translation="MQVNKVIYILLALFLGSFGIHKFYAGKNMQGILHLIFCWTGIPH
                     ILAIISAVITVFKPADEQGNVTL"
     gene            22209..22697
                     /locus_tag="RFE25_000505"
     CDS             22209..22697
                     /locus_tag="RFE25_000505"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDU2815605.1"
                     /translation="MAIKKLVPASHPILTKKAQAVKTFDDSLKRLLQDLEDTMYAQEA
                     AGLCAPQINQSLQVAIIDMEMEGLLQLVNPKIISQSNETITDLEGSITLPDVYGEVTR
                     SKMIVVESYDVNGNKVELTAHEDVARMILHIIDQMNGIPFTERADRILTDKEVEAYFI
                     ND"
     gene            22690..23625
                     /locus_tag="RFE25_000506"
     CDS             22690..23625
                     /locus_tag="RFE25_000506"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDU2815606.1"
                     /translation="MTKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMT
                     PPPVKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVDLIVTAAFGQLLPESLLALPKLG
                     AINVHASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDN
                     VGTMHDKLSVLGADLLKETLPSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGR
                     QVFNQIRGLSPWPVAYTTMDDTNLKIYDAELVETNKINEPGTIIETTKKAIIVATNDN
                     EAVAIKDMQLAGKKRMLAANYLSGAQNTLVGKKLI"
     gene            23622..24929
                     /gene="rsmB"
                     /locus_tag="RFE25_000507"
     CDS             23622..24929
                     /gene="rsmB"
                     /locus_tag="RFE25_000507"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDU2815607.1"
                     /translation="MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALF
                     TEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVE
                     IAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDHWATHYG
                     LEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQP
                     IIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQV
                     DASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHK
                     PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKN
                     NKNFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN"
     gene            24932..26026
                     /gene="rlmN"
                     /locus_tag="RFE25_000508"
     CDS             24932..26026
                     /gene="rlmN"
                     /locus_tag="RFE25_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002435140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDU2815608.1"
                     /translation="MITAEKKKKNKFLPNFDKQSIYSLRFDEMQNWLVEQGQQKFRAK
                     QIFEWLYQKRVDSIDEMTNLSKDLRQLLKDNFTVTTLTTVVKQESKDGTIKFLFELQD
                     GYTIETVLMRHDYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKA
                     LDATEERVSQIVIMGIGEPFENYDEMMDFLRIVNDDNSLNIGARHITVSTSGIIPRIY
                     DFADEDIQINFAVSLHAAKDEVRSRLMPINRAYNVEKLIEAIQYYQEKTNRRVTFEYG
                     LFGGVNDQLEHARELAHLIKGLNCHVNLIPVNHVPERNYVKTAKNDIFKFEKELKRLG
                     INATIRREQGSDIDAACGQLRAKERQVETR"
     gene            26033..26776
                     /locus_tag="RFE25_000509"
     CDS             26033..26776
                     /locus_tag="RFE25_000509"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase Stp1"
                     /protein_id="HDU2815609.1"
                     /translation="MLEAQFFTDTGQHRDKNEDAGGIFYNQTNQQLLVLCDGMGGHKA
                     GEVASKFVTDELKSRFEAENLIEEHQAENWLRNNIKDINFQLYHYAQENAEYKGMGTT
                     CVCALVFEKSVVIANVGDSRAYVINSRQIEQITSDHSFVNHLVLTGQITPEEAFTHPQ
                     RNIITKVMGTDKRVSPDLFIKRLNFYDYLLLNSDGLTDYVKDNEIKRLLVKEGTIEDH
                     GDQLMQLALDNHSKDNVTFILAAIEGDKV"
     gene            26773..28767
                     /gene="pknB"
                     /locus_tag="RFE25_000510"
     CDS             26773..28767
                     /gene="pknB"
                     /locus_tag="RFE25_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase Stk1"
                     /protein_id="HDU2815610.1"
                     /translation="MIGKIINERYKIVDKLGGGGMSTVYLAEDTILNIKVAIKAIFIP
                     PREKEETLKRFEREVHNSSQLSHQNIVSMIDVDEEDDCYYLVMEYIEGPTLSEYIESH
                     GPLSVDTAINFTNQILDGIKHAHDMRIVHRDIKPQNILIDSNKTLKIFDFGIAKALSE
                     TSLTQTNHVLGTVQYFSPEQAKGEATDECTDIYSIGIVLYEMLVGEPPFNGETAVSIA
                     IKHIQDSVPNVTTDVRKDIPQSLSNVILRATEKDKANRYKTIQEMKDDLSSVLHENRA
                     NEDVYELDKMKTIAVPLKKEDLAKHISEHKSNQPKRETTQVPIVNGPAHHQQFQKPEG
                     TVYEPKPKKKSTRKIVLLSLIFSLLMIALVSFVAMAMFGNKYEETPDVIGKSVKEAEQ
                     IFNKNNLKLGKISRSYSDKYPENEIIKTTPNTGERVERGDSVDVVISKGPEKVKMPNV
                     IGLPKEEALQKLKSLGLKDVTIEKVYNNQAPKGYIANQSVTANTEIAIHDSNIKLYES
                     LGIKQVYVEDFEHKSFSKAKKALEEKGFKVESKEEYSDDIDEGDVISQSPKGKSVDEG
                     STISFVVSKGKKSDSSDVKTTTESVDVPYTGKNDKSQKVKVYIKDKDNDGSTEKGSFD
                     ITSDQRIDIPLRIEKGKTASYIVKVDGKTVAEKEVSYDDI"
     gene            28995..29870
                     /gene="rsgA"
                     /locus_tag="RFE25_000511"
     CDS             28995..29870
                     /gene="rsgA"
                     /locus_tag="RFE25_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499727.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDU2815611.1"
                     /translation="MKTGRIVKSISGVYQVDVNGERFNTKPRGLFRKKKFSPVVGDIV
                     EFEVQNINEGYIHQVFERKNELKRPPVSNIDTLVIVMSAVEPNFSTQLLDRFLVIAHS
                     YQLNARVLVTKKDKTPIEKQFEINELLKIYENIGYETEFIGNDDDRKKIVEAWPAGLI
                     VLSGQSGVGKSTFLNHYRPELNLETNDISKSLNRGKHTTRHVELFERQNGYIADTPGF
                     SALDFDHIDKDEIKDYFLELNRYGETCKFRNCNHIKEPNCNVKHQLEIGNIAQFRYDH
                     YLQLFNEISNRKVRY"
     gene            29871..30515
                     /locus_tag="RFE25_000512"
     CDS             29871..30515
                     /locus_tag="RFE25_000512"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDU2815612.1"
                     /translation="MTKLYPSLLSVDFLDLQHELKRLEEAGVDGVHFDVMDGQFVPNI
                     SIGLPILDAVRKGTTLPIDVHLMIENPEKYIASFAEHGADMISIHVESTPHIHRAIQM
                     IKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNA
                     IKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG"
     gene            30522..31163
                     /locus_tag="RFE25_000513"
     CDS             30522..31163
                     /locus_tag="RFE25_000513"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDU2815613.1"
                     /translation="MHINLLCSNRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFF
                     SVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGR
                     LDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTD
                     DVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN"
     gene            complement(31544..31732)
                     /locus_tag="RFE25_000514"
     CDS             complement(31544..31732)
                     /locus_tag="RFE25_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDU2815614.1"
                     /translation="MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKP
                     KKVWVSARALKSGKVTRV"
     gene            32175..32549
                     /locus_tag="RFE25_000515"
     CDS             32175..32549
                     /locus_tag="RFE25_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDU2815615.1"
                     /translation="MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRD
                     GIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLN
                     VSVNSINIYVQGVRVNNTGKKA"
     gene            32564..34210
                     /gene="fakA"
                     /locus_tag="RFE25_000516"
     CDS             32564..34210
                     /gene="fakA"
                     /locus_tag="RFE25_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid kinase catalytic subunit FakA"
                     /protein_id="HDU2815616.1"
                     /translation="MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTN
                     MNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESES
                     EINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYI
                     IVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKIDKDE
                     FVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDE
                     EIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETA
                     IITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNIL
                     MASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLT
                     YAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLAEDSEILTVIIGQ
                     DAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE"
     gene            34400..36460
                     /gene="recG"
                     /locus_tag="RFE25_000517"
     CDS             34400..36460
                     /gene="recG"
                     /locus_tag="RFE25_000517"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDU2815617.1"
                     /translation="MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPT
                     RYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFN
                     QPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEG
                     IKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRT
                     YAFTELFLFELRMQWLNRLEKSSDEAIEIDYDLDQVKSFIDRLPFELTEAQKSSVNEI
                     FRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLM
                     ALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITD
                     EQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPII
                     TTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGV
                     SRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGL
                     STLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGD
                     FFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLH
                     RSFD"
     gene            36663..37235
                     /gene="fapR"
                     /locus_tag="RFE25_000518"
     CDS             36663..37235
                     /gene="fapR"
                     /locus_tag="RFE25_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDU2815618.1"
                     /translation="MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIR
                     LDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSV
                     FHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQT
                     AKHYYVEVKSYVKHTLVFKGNFKMFYDKRG"
     gene            37240..38226
                     /gene="plsX"
                     /locus_tag="RFE25_000519"
     CDS             37240..38226
                     /gene="plsX"
                     /locus_tag="RFE25_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDU2815619.1"
                     /translation="MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKNLEIMLFGDEKKYN
                     LNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALM
                     SVGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQ
                     KIRGIDNPKISLLNIGTEPAKGNSLTKKSFELLNQDHSLNFVGNIEAKTLMDGDTDVV
                     VTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEY
                     GGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE"
     gene            38219..39145
                     /gene="fabD"
                     /locus_tag="RFE25_000520"
     CDS             38219..39145
                     /gene="fabD"
                     /locus_tag="RFE25_000520"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDU2815620.1"
                     /translation="MSKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAAKTLDFDI
                     LETMFTDEEGKLGETENTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVL
                     SFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANIN
                     CPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFE
                     WRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPG
                     KVLSGLIKKINRDVKLTSIQTLEDVKGWNEND"
     gene            39138..39872
                     /gene="fabG"
                     /locus_tag="RFE25_000521"
     CDS             39138..39872
                     /gene="fabG"
                     /locus_tag="RFE25_000521"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDU2815621.1"
                     /translation="MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVV
                     EEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQ
                     EWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVI
                     GLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIAN
                     TVAFLASDKAKYITGQTIHVNGGMYM"
     gene            40307..40540
                     /locus_tag="RFE25_000522"
     CDS             40307..40540
                     /locus_tag="RFE25_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002510960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDU2815622.1"
                     /translation="MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVM
                     ELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK"
     gene            40656..41387
                     /locus_tag="RFE25_000523"
     CDS             40656..41387
                     /locus_tag="RFE25_000523"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDU2815623.1"
                     /translation="MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFI
                     NDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIF
                     ANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFP
                     HVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAE
                     GKGKTKKESEQRAAESAYKQLKQIK"
     gene            41534..45100
                     /gene="smc"
                     /locus_tag="RFE25_000524"
     CDS             41534..45100
                     /gene="smc"
                     /locus_tag="RFE25_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDU2815624.1"
                     /translation="MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDA
                     IKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVT
                     RRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQ
                     IIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKT
                     LSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGK
                     RHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLE
                     NISNEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSE
                     QSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELS
                     AVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGV
                     KHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFL
                     KERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLG
                     NTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTT
                     MRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLT
                     TQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLS
                     KEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQSQQTKHQLKDVKEKIAF
                     FNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEATLQVCH
                     QDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKK
                     VKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVT
                     ERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLL
                     SGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVI
                     THRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ"
     gene            45100..46350
                     /gene="ftsY"
                     /locus_tag="RFE25_000525"
     CDS             45100..46350
                     /gene="ftsY"
                     /locus_tag="RFE25_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDU2815625.1"
                     /translation="MSFFKRLKDKFATNKENEEVKSLREEQGQDKLEDTHSEGSTQDV
                     NDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQ
                     LNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREV
                     IVEKIVEIYHQEDDNSEAMNIEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVM
                     LAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDT
                     AGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVT
                     GIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQ
                     NDEITTVENDQIVTEEKDDNHGAK"
     gene            46337..46669
                     /locus_tag="RFE25_000526"
     CDS             46337..46669
                     /locus_tag="RFE25_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDU2815626.1"
                     /translation="MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEI
                     ADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRY
                     IQQLEDLE"
     gene            46695..48062
                     /gene="ffh"
                     /locus_tag="RFE25_000527"
     CDS             46695..48062
                     /gene="ffh"
                     /locus_tag="RFE25_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002457378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDU2815627.1"
                     /translation="MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALFEADV
                     NFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPT
                     VVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPV
                     YSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKEIAKPNEI
                     MLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGM
                     SEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDF
                     LEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPD
                     TLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKG
                     MNLPF"
     gene            48497..48772
                     /gene="rpsP"
                     /locus_tag="RFE25_000528"
     CDS             48497..48772
                     /gene="rpsP"
                     /locus_tag="RFE25_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDU2815628.1"
                     /translation="MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTS
                     ANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK"
     gene            48960..49463
                     /gene="rimM"
                     /locus_tag="RFE25_000529"
     CDS             48960..49463
                     /gene="rimM"
                     /locus_tag="RFE25_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDU2815629.1"
                     /translation="MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNN
                     DLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDI
                     IGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIIT
                     PMEGLLD"
     gene            49463..50200
                     /gene="trmD"
                     /locus_tag="RFE25_000530"
     CDS             49463..50200
                     /gene="trmD"
                     /locus_tag="RFE25_000530"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDU2815630.1"
                     /translation="MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAIN
                     KHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSK
                     ADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGN
                     EQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKR
                     PDLIEKYPLTNEDKQILERYKIGLKKG"
     gene            50303..50653
                     /gene="rplS"
                     /locus_tag="RFE25_000531"
     CDS             50303..50653
                     /gene="rplS"
                     /locus_tag="RFE25_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011303276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDU2815631.1"
                     /translation="MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQV
                     FEGIVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYL
                     RSLRGKAARIQEIR"
     gene            complement(50897..53503)
                     /gene="yfhO"
                     /locus_tag="RFE25_000532"
     CDS             complement(50897..53503)
                     /gene="yfhO"
                     /locus_tag="RFE25_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoteichoic acid-specific glycosyltransferase
                     YfhO"
                     /protein_id="HDU2815632.1"
                     /translation="MLKKWLNSNVKQFFVITFISVILTLILFSTHIYDYIVNGTVFSG
                     AGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLFIK
                     IGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGM
                     STVVIYFNFTWSFYGNLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQ
                     AIIIGCYYLYRLIFTYKYDIVSRTQKFICVISATVLSVLSSVFGLFTGISAFLENDRK
                     QNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWILF
                     IGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSI
                     IALLYVLLSPTHPLALIVGIILLMVLAVILKFSLWRYKKLTVAILVLIVMIQQIVILD
                     NNKNMAIKPYQQSLSTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFI
                     YHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRV
                     NHDDNLPYRFKINSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAML
                     QGIVSNNTKDVNTHFKANKNLLSDSTIKLNSSAWQSPTKHLLQVKQNNGGLTVQLPKS
                     VSNQFKDLYFEMDLELLSPDKAHDVKVNEYTQERNKLTYKYRRFVTPVTIRIKASDRI
                     RLSLPKGKYRVNLKGIYGEDYTTLKDASNSLEAVKVSKTKQGYTITKNKNSSGYIVLP
                     TAYNQGMKATSGDQSLKVAQVNGVMTGIKAPKNITKIQLSYTPPYYYLLITITIFGII
                     CSIIFTRWARQK"
     gene            53904..54788
                     /gene="ylqF"
                     /locus_tag="RFE25_000533"
     CDS             53904..54788
                     /gene="ylqF"
                     /locus_tag="RFE25_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDU2815633.1"
                     /translation="MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMI
                     DEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIK
                     ATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQW
                     IKVSNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQNDL
                     ARLKSHYNIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNY
                     CFDIFKDMTEELANDANN"
     gene            54772..55539
                     /locus_tag="RFE25_000534"
     CDS             54772..55539
                     /locus_tag="RFE25_000534"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDU2815634.1"
                     /translation="MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKA
                     LEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNY
                     LGLDDSKKVPITKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGL
                     SVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEY
                     GFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL"
     gene            55648..56814
                     /gene="sucC"
                     /locus_tag="RFE25_000535"
     CDS             55648..56814
                     /gene="sucC"
                     /locus_tag="RFE25_000535"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HDU2815635.1"
                     /translation="MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYV
                     VKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGC
                     AIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
                     RRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINF
                     DDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTI
                     NHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVE
                     AVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA"
     gene            56836..57744
                     /gene="sucD"
                     /locus_tag="RFE25_000536"
     CDS             56836..57744
                     /gene="sucD"
                     /locus_tag="RFE25_000536"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HDU2815636.1"
                     /translation="MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKG
                     GQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPV
                     LDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYE
                     AVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEA
                     AEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAAT
                     PSEIGSTLIEAAKEAGIYESLLTVNK"
     gene            57971..59089
                     /locus_tag="RFE25_000537"
     CDS             57971..59089
                     /locus_tag="RFE25_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDU2815637.1"
                     /translation="MNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKS
                     KDFTRGYEQNVFAKSELNANKNTTKDKIKNEGAVKTSDTSLKLDNKSAISNGNEINQD
                     IKISNTPKNSSQGNNLVINNNEPTKEIKIANLEAQNSNQKKTNKVTNNYFGYYSFREA
                     PKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKP
                     KTVSSNNKSNSNSSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGA
                     KDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKF
                     QSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA"
     gene            59117..>59896
                     /gene="fmhC"
                     /locus_tag="RFE25_000538"
     CDS             59117..>59896
                     /gene="fmhC"
                     /locus_tag="RFE25_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FemA/FemB family glycyltransferase FmhC"
                     /protein_id="HDU2815638.1"
                     /translation="MKFSTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGV
                     KNDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGV
                     FILVDPYLIENLRDANGRIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVL
                     DLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHF
                     MNEDYFKRMQEIYKDKAMLKIACINLNEYQDKLKIQLLKIEN"
BASE COUNT        22010 a         8215 c        11400 g        18271 t
ORIGIN      
        1 ggacccatca tcaaaaattc tatttataga attttacagt aatgtgccag atgggcatag
       61 cgaagccatt caatacgaag tattgtataa atagagaaca gcagtaagat aatttttaat
      121 tagaaaatat cttactactg tctttttagg gatttatgtt ccagcctgct ttcctaattt
      181 ttaatgtcat cttaaatatg ataaatgaat aattaagttc atatttaatg tcaaaacata
      241 gtagtttatc aagtattgag tgagtaacat tagatttaat gtaatatgct tacttttttt
      301 attagcaggt gtaagctata atataaagag ttgtcttatg gacgattgat tggaggaacg
      361 aaaatgcaca aaaaatattt tattggcact tccattttaa tagcagtatt tgtcgttata
      421 tttgaccaag ttactaaata tattatagct actacaatga aaattggaga ttcatttgaa
      481 gtgataccgc actttttaaa cataacatca catcgaaata atggtgctgc atggggaata
      541 ttgagtggaa aaatgacatt tttctttatt attaccatta ttatattaat agccttagta
      601 tatttcttta ttaaagatgc tcaatataat ttgtttatgc aagttgctat tagtttactt
      661 tttgcaggtg cacttggaaa ctttattgat agaattttaa caggagaagt tgttgacttt
      721 attgatacaa atatttttgg ttatgatttt ccaatattta atatagcaga ttcaagttta
      781 acaattggtg taatattaat tattattgcc ttattaaagg atacttccaa taaaaaggag
      841 aaggaggtta agtaatggag acttatgaat ttaacattac agataaagaa caaacaggta
      901 tgcgtgtaga taagttgctg cctgaattaa ataatgattg gtctcgtaac cagatacaag
      961 attggattaa agcaggttta gtcgttgcaa acgataaagt tgttaaatct aattataaag
     1021 tgaaacttaa tgatcatata gttgtcactg aaaaagaagt ggttgaagct gatattctac
     1081 ctgaaaattt aaatttagat atttattatg aagatgacga tgttgcagtt gtatataaac
     1141 cgaaaggcat ggtagttcat ccatcaccag ggcattatac caatacatta gttaatggtt
     1201 taatgtatca aattaaaaat ttgtcaggta ttaatggaga aattcgtcca ggtattgttc
     1261 accgtataga tatggatact tctggtttat taatggttgc taaaaatgat attgctcatc
     1321 gtgggcttgt agaacaatta atggataaat ctgttaaaag aaaatatatc gctttagttc
     1381 acgggaatat tcctcatgat tacggtacaa tcgatgcgcc aattggtaga aacaaaaatg
     1441 atcgtcaatc tatggctgtt gttgatgatg gtaaggaagc agtgacacat tttaacgtac
     1501 tagaacattt taaagattat acgcttgttg aatgtcaact tgaaacagga cgtacgcatc
     1561 aaatccgtgt gcacatgaaa tatattggct tcccattagt tggtgatcca aagtatggac
     1621 cgaaaaagac attggatatt ggtggtcaag ctctacatgc tggacttatt ggattcgaac
     1681 atccagtaac aggtgaatat attgaaagac atgctgaatt accacaagac tttgaagatt
     1741 tattagatac aattcgaaaa agagatgcat aattgtgttg tgctataatt acgataacat
     1801 tattatgtaa actataagta tttatcgttt tcgttttttt aaaatgaaaa cacattataa
     1861 aatagattaa ggttaacatt tttactgaga tcggttaatt tttcaatata gattgacaaa
     1921 gcgcctgatt agtattatcc ttataacagt ttaagtacaa cataaagagt ctttaattga
     1981 gcgtccagag agacgtcaaa gacatgaaaa tatagatata tactaaaatg atcataacac
     2041 tttcacatat gcaagaataa gtagtaatac tacgattctt ctatgtaaat aggctgattg
     2101 tatatactaa acctcatgtc gatattaaag acatgaggtt ttttgtttct aaattttgaa
     2161 agggtgagaa tatgtctgaa cgtattataa tggatgatgc cgcaatacaa cgtacagtga
     2221 cgagaatcgc tcacgaaatt ttggagtata acaaaggtac tgataattta attcttttag
     2281 gtatcaaaac aagaggtgaa tatttagcga atcgtataca agataaaatt catcaaattg
     2341 agcaacaacg tatacctact ggaacaattg atattacata ctttagagat gatatagagc
     2401 acatgtcatc acttacgaca aaagacgcaa tagacatcga cacagatatt acagataaag
     2461 tagtcatcat tattgatgat gtgctgtata ctggtcgaac ggttcgtgct tcacttgatg
     2521 ctattttgct aaatgctaga cctattaaaa ttggtttagc tgctttggtt gatcgaggac
     2581 atcgtgagtt accaattcga gcagattttg ttggtaaaaa tatacctact tctaaagagg
     2641 aaacggtaag tgtctattta gaagaaatgg atcaaagaaa tgcagttata attaaataat
     2701 acccctttta attcagtacg agagactgaa aaaggtgggg gagttaaatg ataaataagt
     2761 tttcatatgc ttgtttatct aataataccc tcatgttcga caactataag tcaatttcta
     2821 tggacgaaaa tgacttatag caacttgtca cactttttgt ctctttacat atactgatgt
     2881 aaagagattt ttttattatc ggaggaaatg aatattatgc aaaatgatga aatgtttgaa
     2941 cgaacagtaa aaccagtact agatgtaaat gaaaaaccac aaccagcgca atgggcattt
     3001 ttaagcttac aacatttatt tgcgatgttt ggcgcaacag tactagtacc attcttaaca
     3061 ggactaccaa tatccgcagc gttactagct tcgggaatcg gtacattact ttatatctta
     3121 ataacgaagg cgcaaatacc agcattcttg ggatctagct ttgcatttat cacaccaatt
     3181 atcacgggat taagtacgca tagcttagga gacatgcttg tagcattatt catgagtggt
     3241 gttatgtacg tcatcatcgg aattctaatc aaattaagtg ggacagcatg gttaatgaaa
     3301 ttattaccac cagttgttgt tggaccagtc atcatggtaa ttggtttaag cttagcgcct
     3361 actgcagtca atatggcaat gtatgaaaat cctggagata tgaaaggtta caatatcagt
     3421 ttcttaattg ttgcaatgat aaccttgctt gtaacaatag tcgttcaagg attttttaaa
     3481 ggattcctat ctttaattcc actacttgta ggtattatcg taggttatgt ggtagcgatt
     3541 tttatgggga ttgtgaaatt tgatgcaatt atgtcagcaa aatggataga tttccctcat
     3601 atttatctgc catttaaaga ttatgtacct tcatttcact taggacttgt acttgtaatg
     3661 attccgattg tgtttgtaac agtaagtgaa catattgggc accaaatggt attgaataaa
     3721 atcgtaggta gaaacttctt tgaaaagcca ggacttgata aatcaatcat tggtgatggt
     3781 gtttctacaa tgtttgccag tattattggt ggaccaccaa gtacaacata cggtgaaaat
     3841 atcggtgtat tagcgattac aagaatatac agtatttacg tcattggtgg tgcagcagtt
     3901 atagcaattg ttttagcatt cattggtaag ttcactgcat taatttcttc tatacctaca
     3961 ccagttatgg gaggagtatc tatattactt ttcggtatta ttgcagcaag tggcttaaga
     4021 atgttagttg aaagcaaagt agattttgcg aacaatcgaa atttagttat agcttctgta
     4081 attttagttg taggtatcgg taatttagta tttaacttaa aagaaattgg tatcaacctt
     4141 caaattgagg ggatggcatt agctgcactt tcaggaatta ttttgaactt aatcttacct
     4201 aaagagaaaa aacaaaacaa ttaagattta caaattaagg agggcgcttt tatgaatcat
     4261 ttattatcaa tggaacattt atctacagat caaatataca aacttatcca aaaggcaagt
     4321 caatttaaat ctggtgaacg tcaactacca aactttgaag ggaaatatgt cgcaaattta
     4381 ttctttgaaa attctactcg aacaaaatgt agttttgaaa tggcagaact taagctaggg
     4441 ttaaaaacga ttagctttga aacatcaaca tcatctgttt caaaaggtga atctttatat
     4501 gacacatgta aaactttaga aagtattggc tgtgatttat tagtcattag acatccgttt
     4561 aataactact atgaaaaatt agcgaatatt aacatcccaa ttgcgaatgc tggtgatggt
     4621 agtggacaac atccaacaca aagtttactt gatttaatga cgatatatga agaatatgga
     4681 tattttgaag gcttgaatgt attgatttgt ggagacatta aaaattcacg tgtcgcacgt
     4741 agtaattacc atagtttaaa agcattaggt gcaaacgtaa tgtttaatag cccaaatgct
     4801 tggattgatg attctttaga agcaccttat gtaaatatag atgatgttat agaaacagta
     4861 gatatagtta tgttattaag aattcaacat gaaagacatg ggcttgcaga agaaactaga
     4921 tttgcagcag atgattatca tcaaaagcat ggcttaaatg aagtgcgcta taacaaatta
     4981 caagaacatg ctattgttat gcatccggca cctgtgaata gaggagtaga aatacaaagc
     5041 gatttagtag aagcttcaaa atcaagaatt tttaagcaaa tggaaaatgg cgtttactta
     5101 agaatggcag tcattgatga attattaaaa taggtaaggg gacgaaaatg atgaaattaa
     5161 ttaaaaacgg taaagtatta caaaatggag aattacaaca agcagatatt ttaattgatg
     5221 gtaaggtaat taaacaaatt gcacctgcaa ttgaaccaag caatggtgtt gacatcatag
     5281 atgcgaaagg tcactttgtg tcacctggat ttgtcgatgt tcatgttcat ttacgtgaac
     5341 ctggtggtga atataaagag acaattgaaa ctggtactaa agctgctgct agaggcggat
     5401 ttacaactgt atgtccaatg cctaacacaa gaccggtacc agattctgta gaacattttg
     5461 aagctttaca aaaattaatc gatgacaatg ctcaagtacg tgtattacct tatgcttcaa
     5521 ttacaacacg tcaattaggt aaagaattgg ttgatttccc agcactagta aaagaaggtg
     5581 cctttgcgtt tacagatgac ggtgtaggag tacaaactgc aagcatgatg tatgaaggca
     5641 tgattgaagc tgcaaaagta aacaaagcca tcgtagcaca ctgtgaagat aattcattaa
     5701 tctatggtgg tgcaatgcat gaagggaaac gcagtaaaga gttaggtata ccaggtattc
     5761 caaacatttg tgaatctgtt caaatcgcaa gagatgtact attagctgaa gcagcaggtt
     5821 gtcattatca tgtatgtcat gtttctacta aagaaagtgt tagagtcatt cgtgacgcta
     5881 aacgcgcagg cattcatgtt acagctgaag ttacaccaca ccatttattg ttaacagaag
     5941 atgatattcc tggtaataat gccatttata aaatgaatcc accattgaga agtactgaag
     6001 atagagaggc tttgttagaa gggttactag acggtacaat tgactgtatc gcaacagacc
     6061 atgcaccaca tgcacgtgat gaaaaagcac aaccaatgga aaaagcacca ttcggaattg
     6121 ttggtagtga aacagcattc ccattattat atacgcattt tgtaaaaaat ggtgattgga
     6181 cattacaaca attagtagat tacttaacaa ttaaaccatg tgagacattt aatttagaat
     6241 acggcacatt aaaagaaaat ggttatgcag atttaacaat cattgattta gatagtgaac
     6301 aagaaattaa aggagaagat ttcttatcaa aagcagataa tacaccattt atcggctata
     6361 aagtttatgg aaatccgatc ttaacaatgg ttgaaggcga agttaaattt gagggggata
     6421 aataatatgc aaagcaaacg ttatctagtg ttagaagacg gttcttttta cgaaggctac
     6481 cgtttaggat ctgataactt aactgtagga gaaattgtat ttaatacagc tatgacaggt
     6541 tatcaagaaa ctatttcaga tccatcatat acaggtcaga tcattacttt tacgtatcca
     6601 ttaatcggta attatggtat caatagagac gattttgaat cattagtacc tacattaaac
     6661 ggtattgtag tgaaagaagc gagtgcgcat ccaagtaatt ttagacaaca aaagacactt
     6721 catgacgttt tagaattgca tcaaattcca gggattgcag gtgttgatac aagaagtatt
     6781 acgcgtaaaa ttcgacaaca cggtgtgtta aaagctggtt ttactgatcg aaaagaagat
     6841 attgatcaac ttgtcaaaca tttacaacaa gtagaattac ctaaaaacga agtagaaatc
     6901 gtttcgacta aaacaccgta tgtttcgaca ggtaaggatc taagtgtcgt acttgtagac
     6961 tttggtaaga agcaaaatat tgttcgagaa ttaaacgtca gaggttgtaa cgtcacagtt
     7021 gtaccatata caactactgc cgaagaaatt ttagcaatgg ctccagatgg cgttatgcta
     7081 tcaaacggac caggtaatcc tgaagttgta gaatgtgcga ttccaatgat tcaaggaatt
     7141 ttagggaaaa ttccgttctt tggtatctgt ctaggacatc aactttttgc attatctcaa
     7201 ggagcaagct catttaaaat gaagtttggt catcgtggtg cgaaccatcc agttaaaaat
     7261 ttagagactg gaaaagttga tattacgagt caaaaccatg gatatgcaat agatatagat
     7321 tcgttaaaaa gtactgattt agaagttact catcttgcat taaatgatgg tactgtagaa
     7381 ggtttaaaac ataaaacatt accagcattt tctgttcaat accatcctga agcaaatcca
     7441 ggaccgtcag attcaaacta tctatttgat gattttgtag caatgatgac taattttaag
     7501 gaaaaggagc gtcatatcaa tgcctaaacg taatgatatc aaaacaattt tagtaatagg
     7561 gtctgggcca attatcatag gtcaagcagc tgaatttgat tatgctggaa cacaagcatg
     7621 tctagcttta aaagaagagg gatatcgagt tattcttgta aattcaaatc cagcgacaat
     7681 catgactgat aaggaaattg cggataaagt atatatcgaa ccgttaactc atgattttat
     7741 agcgcgaatt atacgtaaag agcaacctga cgctttactt ccaactttag gtggtcaaac
     7801 aggtttaaac atggcgattc aactacacga aagtggtgtg cttcaagata ataacgtcca
     7861 attattagga actgagctaa catcaattca acaagcagaa gaccgtgaaa tgtttagaac
     7921 attaatgaat gatttaaacg ttcctgtacc agagagtgac attgtaaata cagtagagca
     7981 agcctttaaa ttcaaagagc aagtgggata cccgctaatt gttagaccgg catttacgat
     8041 gggtggtacc ggaggcggta tttgtcataa tgatgaagaa ttacatgaaa tcgtctcaaa
     8101 tggtcttcat tatagtccag caacgcaatg tttattagaa aaatctatcg caggttttaa
     8161 agaaatcgaa tacgaagtaa tgcgtgataa aaacgataat gccatcgttg tatgtaacat
     8221 ggaaaatatt gatccagttg gtattcatac tggcgattca attgttgtgg ctcctagtca
     8281 aacattatca gatgttgagt atcaaatgtt acgtgatgtt tcattaaaag ttattcgagc
     8341 tttaggtatc gaaggtggtt gtaatgttca attagcatta gatccccatt cattcgatta
     8401 ttatattata gaagtaaatc cgcgtgtatc acgttcatca gcgttagctt caaaagcaac
     8461 aggatatcct attgcaaaat tagctgctaa aatcgcggtt ggtctaacat tagatgaaat
     8521 gttaaatcca attacaggaa catcttatgc agcgtttgaa ccaactttag actatgtgat
     8581 ttcaaaaata ccaagatttc cttttgataa atttgaaaaa ggagaacgag agcttggcac
     8641 acaaatgaaa gcaacaggtg aagttatggc cattggtcga acttacgaag aatcattgtt
     8701 aaaagcaatt cgatcacttg agtatggtgt gcatcactta ggattaccaa atggtgaaag
     8761 cttcgatctt gattatatta aagaacgtat ttcacaccaa gatgatgaac gattattttt
     8821 catcggcgaa gcaattagaa gagggacaac attagaagaa attcataata tgactcagat
     8881 tgattacttc ttcttacaca agttccaaaa cattattgat attgagcatc aattaaaaga
     8941 gcatcaaggt gatttagaat atcttaaata tgcaaaagat tatggattta gtgataaaac
     9001 aatagcgcat cgctttaata tgacggaaga agaagtatat caattgcgta tggaaaatga
     9061 tattaaacct gtttacaaga tggttgatac ttgcgcagct gaatttgaat cttcaacacc
     9121 atattattat ggtacatacg aaactgaaaa tgaatccata gttactgaca aagaaaaaat
     9181 cttagtatta ggctctggac caattcgaat cggccaaggt gtagaatttg actatgcgac
     9241 agttcacgcc gtttgggcaa ttcaaaaagc agggtacgaa gcgataattg tgaataacaa
     9301 tccagaaaca gtttcaacag acttctcaat ttctgacaaa ttatactttg aacctttaac
     9361 tgaagaagat gtgatgaata tcattaattt agaaaaacct aaaggtgtcg ttgtacaatt
     9421 tggaggacaa acagcgatta atttagcaga caaattggct aaacatggtg ttaaaatact
     9481 tggtacttca ctagaaaatc taaatcgtgc tgaagataga aaagaatttg aagcactatt
     9541 aagaaaaatt aacgtgccac agccacaagg gaaatcagct acatcacctg aggaagcatt
     9601 agcgaatgct gcagaaatcg gatatccggt tgtagtaaga ccttcttatg tattaggtgg
     9661 tcgcgcaatg gaaattgtag acaatgacaa agagttagaa aactatatga cccaggctgt
     9721 aaaagcgagt ccggaacatc cggtactagt cgatagatat ttaactggta aagaaattga
     9781 agttgatgcg atttgtgatg gagaaacggt cattattcca ggaatcatgg aacatattga
     9841 acgtgctggt gtacatagtg gtgactcaat cgctgtatat ccgccacaaa ctttgacaga
     9901 agacgagtta gcaacacttg aggactatac tataaaatta gctaaaggtt taaacatcat
     9961 tggcttaatc aacattcaat tcgttatagc tcacgatggt gtatatgttt tagaagtaaa
    10021 cccacgttct agtagaacgg taccattctt aagtaaaatt actgatattc caatggcaca
    10081 attagctatg cgagcaatca ttggggaaaa actaacagat atgggttatc aagaaggggt
    10141 tcaaccatat gctgagggtg tatttgtgaa agcaccggta tttagtttta ataaattgaa
    10201 aaatgttgat attactttag gacctgaaat gaagtctaca ggtgaagtaa tggggaaaga
    10261 tactacatta gaaaaggcgt tattcaaagg gttaacaggt agtggtgttg aagttaaaga
    10321 tcacggtaca gtattaatga ccgtcagtga caaagataaa gaggaagttg ttaaattggc
    10381 acaacgctta aatgaagttg gctataaaat tttagcaacg tctggaacag ctaataaatt
    10441 agctgagtat gacatacctg cagaagtagt aggcaaaatc ggtggcgaaa atgatttatt
    10501 aacacgtatt caaaatggtg atgttcaaat cgttataaat acaatgacta aaggtaaaga
    10561 agtagaaagg gatggcttcc aaattagacg tactacagtt gaaaatggta ttccatgttt
    10621 gacatcttta gatacagcta atgccttaac gaatgtaatt gaaagtatga catttacaat
    10681 gcgtcaaatg taaatcaatc aaactgtatc ggtggggctg taattaacca tttacttaaa
    10741 gaagtttata ttacagcctc attattttaa tgaatttctt aatataaagg gagacatata
    10801 tgatgaaaga tttaccaatt attgcattag attttgaatc aaaagaaaaa gtaaatcaat
    10861 ttttagattt atttgatgaa tcattattcg taaaagtagg tatggaactt ttttatcaag
    10921 aaggtcctca attaattaat gagataaaag aaagaggcca tgatgtattt ttagatttaa
    10981 aactgcatga tattcctaat acagttggta aggcgatgga aggactagct aaattgaatg
    11041 ttgatctggt aaatgttcat gctgctggtg gcgtaaaaat gatgtctgag gccattaaag
    11101 gattaagaaa acataatcaa catacaaaaa ttattgcagt aacacagctt acgtcaacaa
    11161 cagaagacat gttacgacac gaacaaaata tacaaacatc gattgaagag gccgttttaa
    11221 attatgccaa gttagcaaat gcagctggtt tagatggcgt tgtttgttca cctcttgaaa
    11281 gtcgtatgtt gactgaaaag ttaggtacat catttttaaa agtaacacca ggtattagac
    11341 ctaaaggtgc atctcaagat gaccaacacc gtattacgac accggaagaa gcaagacagc
    11401 ttggttcgac gcatattgta gtcggtagac cgattacaca aagtgacaat ccagtcgaaa
    11461 gttatcataa aattaaagaa agttggttag tataatggct aaagaaattg caaaatcatt
    11521 attagatatt gaagctgtaa cattatcacc aaatgattta tatacatgga gttcaggtat
    11581 taaatcaccg atttactgtg ataaccgtgt tacgttaggt tatcctttag ttcgaggcgc
    11641 aatccgcgat ggtttaatta acttaattaa agaacacttt cctgaagtag aagttatttc
    11701 tggtactgca acagctggta ttccacatgc agcttttatt gctgaaaaat taaaattacc
    11761 aatgaattat gttcgttcat caaataagag tcatggtaag caaaatcaaa tcgaaggtgc
    11821 taaaagtgaa ggtaaaaaag tagttgtgat agaagattta atttcgacag ggggatcttc
    11881 agtcacagca gttgaagcct taaaacaagc aggtgcagaa gtattaggtg ttgtagctat
    11941 ctttacttac ggtttgaaaa aagcagatga tacatttagc aatattcaac taccttttta
    12001 cactttaagt gattacaatg aattaattga agtagctgaa aatgaaggta aaatttctag
    12061 tgaagatatc caaacattag ttgaatggag agacaactta gcataatata gacactagaa
    12121 ggaggaattc aacaaatgaa tgacaaaaca tctaatgatt tatatgggaa gataaaacat
    12181 tgtaacgaat ttatcaatca ttcaaatgat tccaatctat ctagtagtca cgatgtcgac
    12241 gaaagttcaa cgaagcaaaa acatataaaa aataaaacaa ctatagatca taatgatgat
    12301 ttatttaaac atgtaaagga tatattacgt aaacaaggac aaatttaaaa acaaaaaagc
    12361 tatagtgttt aatatcaggg gctgcttaac cgcatccgaa tattacaaac actatagctt
    12421 ttattatata aaaaatttat tagcggataa ttaactttat taaaatccaa ccaattaaga
    12481 atacgagtaa taggactaat actggaatca cataatgtaa cataacgtcc ctcctttaac
    12541 ttaattttaa ttgtaatcaa atttgacaat aagtcaaaac attaatacct atgataagta
    12601 tcatttatta acatatgtat catattttta atcttgcgta atttttatcg ttaactatgt
    12661 gatttaatca acaggccaat aagacgtttg tcattcgtgc acataacggt atgacgcgct
    12721 tttgtcattt taattatgtt aagataatag tagttataga agttcgatct ataggaggca
    12781 tagcatggat attccaaaaa tcacgacatt tttaatgttt aataacaaag ctgaagaagc
    12841 tgttaaacta tacacaagct tatttgaaga tagtgagatt ataacaatgg ctaagtatgg
    12901 tgaaaatgga cctggtgatc acgggactgt acaacactca atatttacat taaatggaca
    12961 agtattcatg gcgattgatg ctaatagtgg cacagaatta ccaatgaatc ctgcgatttc
    13021 attatttgtt acagtaaaag atactattga aatggaacga ctatttaatg gattaaaaga
    13081 tgaaggtgcc attttaatgc caaaaacgaa tatgccacca tacagagagt ttgcttgggt
    13141 tcaagataag tttggagtaa gttttcaatt agcattacct gagtaaaagg attcgcacag
    13201 cgttgaatga taaagaaaca ctttttctta tgcatgcgtt ttacctatgt atttctattt
    13261 taagtacaca ttagcatttt agtttcactc atttttaaaa tcacaaagat aatttgtaac
    13321 ttaaatgatg atacgttatt taaaaacacg atacttcgtt tcaatgaacg cattaaataa
    13381 taaataaaca cctcgcaaaa gaaagtagtc ctttcttatg gtgaggtgtt tatttgtcga
    13441 caacttgatt ataattgttt cattttttga ataagttcat aatcaggtgt agcatacaaa
    13501 gttttttgat tgtcatatgt tacaaaccca ggctttgcac ctgatggttt gtgcacattt
    13561 ttaattaatg tgtaatcaac aggtatttgt ccagaattac cagcttttga aaagtatcct
    13621 gctaacatag ccgcttcctt gattgtcgta tcacttggtg catcattaaa tataacgaca
    13681 tgtgaaccag gaatatcttt tgtgtgtaac catgtgtgag tttttttagc ttttttattt
    13741 gttaaataat cattttgctt gttattcttg ccaacatata tatcgtcgcc atcagttgat
    13801 acataatgtt gtaattgaat ctgcgctttc tttttcttag tttgattttt acgctgtttc
    13861 ataaagcctt gttctgctaa ttcatctcta atttcatcaa tgtcatggac agaaatatga
    13921 tgtaattgtt gttcgattgt tgaaaaataa tctatattat ctttcgtcaa ttgaatttga
    13981 tgttgtaatt cacgttctct cgttttcata cgattatatt gtttataata atattgagca
    14041 tttgctgatg gggattttgt aggatttaaa ggaatgacaa cttcttcatt cgtataataa
    14101 ttcaatgctg tcacttcttt atcgccttgc ttaattcgat atatattagc agtgatcaat
    14161 tcaccatata actgttcggt atctttattt ttagactgct catattcttc aatcaacttc
    14221 gctaatttat tttgatattt gtgcaactgc tgttgaacaa atcgaactaa atcattcgca
    14281 cgttgtttaa cgcgttcacg ttcgccacgc gcgtcataaa aacgatcaag taaatcattt
    14341 aatgaatcgt acgtaactgt atcatcatta aattgattta actttataaa atagaaatcc
    14401 tctttacctg tttcatgatt tttatgaaaa ataggagtag gtggtaactt ggtttctgcc
    14461 attacttcgt cgaatgcttc tggtaatgtt gatgaagtca taaattgacg acgactaacg
    14521 atttcattcg taattaaagg gctaaatcct tcaaactgat tcaataattg tttagcaata
    14581 ttacctgcgt taaaatcgat atatttcaac acctctgcac ctgtaatatc atacggattt
    14641 attttgtgct gagtaggtgg tgcttcataa ttaaatcctg gcattactgt acgatagtga
    14701 ttcgtatttg gtgttaagtg tttaaatcct tcaattattt tgcgattttc atctactaaa
    14761 attaagttac tatgtttacc cataatctca aggatgacag tgcggtaaat agtatcgcca
    14821 atttcatctt tactctttat atcgatttca atgcgacgat cattaccaat ttgcttaatc
    14881 gattcgataa taccaccttc taagtgtttt ctaaaaacac gcgcaaacat gggtggatta
    14941 aatggattat catatttttt agtagtcaat tgtaatcttg aaaagtttgg atggattgac
    15001 aataacaatt gatggttttg tctattttga cgtacaacca ttagtatcgt gtcattatca
    15061 ggttgattga ttttgtgaac gcgtcctgtt gttaaaaatt gtagagactc aaccattttc
    15121 tttgtaaata atccatcata agccataatt tatcttccac cttcttcata tcattcgttt
    15181 cattttaaca tgattgtaac ttttcggtat agttattgaa ccatacatta tgccacacat
    15241 tttacattat ctaaaagttc gcaattcaat ttatttaatt aaaattaatc gtgcaatata
    15301 acgatattgt tagacttaat agaaattatg gcatgcaatt tcaaatatgc tatacaatat
    15361 aaagaacaat gtgatatcat atttaaataa tagaagatta gcttagagag gtcgtaaggc
    15421 atggataatg aaaaaggatt gttaatcgtt ttatcaggac catctggagt aggtaaaggt
    15481 actgttagaa aacgaatatt tgaagatcca agtacatcat ataagtattc tatttcaatg
    15541 acaacacgtc aaatgcgtga aggtgaagtt gatggcgtag attacttttt taaaactagg
    15601 gatgcgtttg aagctttaat taaagatgac caatttatag aatatgctga atatgtaggc
    15661 aactattatg gtacaccagt tcaatatgtt aaagatacaa tggacgaagg tcatgatgta
    15721 tttttagaaa ttgaagtaga aggtgcaaag caagttagaa agaaatttcc agatgcgtta
    15781 tttattttct tagcacctcc aagtttagat cacttgagag agcgattagt aggtagagga
    15841 acagaatcca atgagaaaat acaaagtcgt attaacgaag cgcgtaaaga agttgaaatg
    15901 atgaatttat acgattacgt tgtagttaat gatgaagtag aacttgcgaa gaatagaatt
    15961 caatgtattg tagaagctga gcacttaaaa agagagcgcg tagaagctaa gtatagaaaa
    16021 atgattttgg aggctaaaaa ataatgttaa atccaccttt aaaccaatta acgtcacaaa
    16081 ttaaatcaaa gtatttaatt gcaacaactg cagcgaaaag agcgcgtgaa attgatgaac
    16141 aacctgaaac tgaattatta agtgaatatc attcatttaa accagttggt agagcgttag
    16201 aagaaattgc tgacggtaaa attcgccctg ttatttcaag tgattattat ggtaaagaat
    16261 agtttcgacc attaaaaata tgtgaagcta gacgtacatc aaatacgtca aggcatatcc
    16321 aaatcaaacg cacctatgta ggtgtgtttt tttagtttat ccaatgattg atgttataat
    16381 aatactaaat ttgtatctat aaaaaagtaa tgagcatttg tgcgcatatg atgatgtaaa
    16441 gcgtaaatgt catagtgata tttaagggag attgaatatg aagaaaatat tattagccgt
    16501 tacaggtggc attgcggcat ataaagcaat tgatttgaca agtaagttaa cacaatctgg
    16561 gtatgaagtt cgcgttatgt taacgaatca cgcacaaaaa tttgtgacac cattagcatt
    16621 tcaagcaata agtcgaaatg ctgtttatac agatactttt atagaagaaa atccttcaga
    16681 aatacagcat attgcattag gtgattgggc agatgcaatc attgttgcac ctgcaacggc
    16741 aaatacaatt gcaaaattga gtgtaggtat tgctgatgat ttggtgacat caacgttgct
    16801 agcaacagag acaccgaaat ttattgcgcc tgctatgaat gtgcatatgt atgaaaataa
    16861 acgtacgcag caaaatatta atattttaaa agaagatggg tatcatttta tcgaaccagg
    16921 aagcggattt ctagcatgtg gttatgttgc taaaggacgt atggaagaac cgcttcaaat
    16981 cgtttctgtt attgatgctc attttcaaaa tagtaatcgt ttagctaata gttcatttca
    17041 agataaacgc gcattggtta cagcaggacc aactattgaa gttatcgatc cagtcagatt
    17101 tgtatccaat cgttcttctg gaaaaatggg ctatgcaata gctgaagcat tgcgaaatcg
    17161 aggagctatc gtgacgttag ttgctggtcc tacaacacta gaggatccaa aagatattga
    17221 agttattcat gttcaaagtg ctgaagaaat gtttgaacaa gtgacaagcc gatttgacga
    17281 acaagatatt gttgtaaaag cagcagccgt atctgactat acaccggttg atgtattaga
    17341 acataagatg aaaaagcagg atggtgattt gtcagtatct tttaaacgta ctaaagacat
    17401 tcttaaatat ttaggtgaac ataaaacatc acagtattta ataggctttg cagcagagac
    17461 tgaagatatt gaaaattatg cacaacaaaa attacgcaag aaaaatgcag atgtgattat
    17521 ttcaaataat gttggggata tgtctatcgg atttagttct gatgataatg aattgacaat
    17581 gcattttaaa aataatgaaa aggtaaatat caagaaagga aaaaaagtag tattagctgc
    17641 acaaatttta gatgaactag aaactaggtg gcaataatga tagcgaaagt catagtcgat
    17701 gtcgcgtcga agagcgttga ctataaattt gattatataa ttcccgaaca actcgaatct
    17761 gtcatccaac ctggtgtgcg tgtaattgta ccttttggac caagaacgat tcaaggttat
    17821 gtaatggaag taacagcaga acctgatgca caacttgacg tttcgaagtt aaaaaaaatc
    17881 atagaagtga aagatataca accagaatta acatcagaat taatagcttt aagtgagtgg
    17941 atgggttcaa ctcatgtcat taaacgtatt tctatgctag aagtgatgct tccaagtgct
    18001 attaaagcga agtataaaaa agcatttaag atgaaagatg acatagagct accttcagct
    18061 ttattacaaa aatttgataa gcatggttac tattattata aagatgcgca aaaaaataat
    18121 gatattcaat tgcttatgaa gttgttaaaa gatgatatcg ttgaagaaaa aacgattctc
    18181 acacaaaata taactaaaaa aaccaagcgt gctgttcgtg tcattgaagg gtatcatcct
    18241 gatgaagtat tagctaagtt ggagaaagtt attaaacaat acgatttgta tgcttacttg
    18301 tctgaagaac aacataaaac aatattttta actgatattg aggatatggg cttttcaaaa
    18361 tccagtttag atggacttat caaaaaaggt tatgttgaaa aatatgacgc ggttgttgaa
    18421 agagacccat ttaaagatcg tgttttcgaa caagaatcaa aacagcaatt aacagaagac
    18481 caatataaag catatgaagc gattaaagct aaaattgtaa gccaagagca agaaacattt
    18541 ttacttcatg gtgtgacggg atcaggtaaa acagaagtat atttacaaac gatagaagat
    18601 gttttaagcc aaggaaaaca ggcgatgatg ttagttcctg aaatcgctct aacaccgcaa
    18661 atggttttac gcttcaaacg tcgatttggt gatgacgttg ctgtattaca ttctggctta
    18721 tctaatgggg aacgttatga tgagtggcaa aaaattaggg atgatcgtgc gagagtaagt
    18781 gttggtgcaa ggtcaagtgt gttcgcacct ttcaaaaatt tagggttaat catcattgat
    18841 gaagaacatg aatctacata taaacaagaa gattatccga gatatcacgc tagagaaatt
    18901 gcccaatggc gaagtgaata tcatcactgt ccagtcattt taggaagtgc aacaccatgt
    18961 cttgaaagtt atgcacgagc tgaaaaagac gtttatcatt tgctatcatt accaaacaga
    19021 gtgaaccaac aagctttacc tgaaattgat atagtagaca tgcgtgaaga attgagtgaa
    19081 ggtaatcggt caatgttttc aaaagattta cgtgaagcca tacaattaag attagatcga
    19141 caggaacaag ttgttttatt tttaaatcga cgtggttatg catcgtttat gttatgtcgg
    19201 gattgtggat atgtaccgca atgtccaaac tgtgatattt cattaacgta tcataaaacg
    19261 acagacttat taaaatgtca ctattgtggt taccaagaga cgccaccgaa tcaatgtcca
    19321 aattgtgaga gtgaacacat tcgacaagta ggtactggta ctcagaaagt tgaagaacta
    19381 ttgcaacaag aatttgaaga tgcgcgcata attaggatgg atgtagatac aacctcaaag
    19441 aaaggtgcac atgaaaagtt attgactgaa ttcgaaaaag gtaacggtga cattttacta
    19501 ggtactcaga tgattgcgaa aggattagat tatccaaata ttactttagt tggtgtgctg
    19561 aatgcagata caatgttaaa tttacctgat tttcgggcga gcgaacgtac ttatcaacta
    19621 ttaacgcaag tggctggtag agctggtcgt catgaaaagg caggtcaagt catcattcaa
    19681 acgtataatc cagatcatta ttcaatattg gatgttcaaa aaaatgatta tttaacattt
    19741 tatcgtcagg aaatggaata tcgtaaatta ggaaagtatc caccgtatta ttatttgatt
    19801 aatttcacaa tctcacataa agaaatgaag aaggttatgg aagcatcgca gcatgttcat
    19861 aaaattttat tacagcattt aacagaaaaa gcgcttgtac taggtccatc tccggcagca
    19921 cttgcgagaa tcaacaatga atttagattc caaattttag tgaaatataa aagtgaacct
    19981 ggattattac aagccattca gtttttagat gactattacc atgaaaaatt tataaaagaa
    20041 aaattagcat tgaagattga tattgatcca cagatgatga tgtaacatta ctaattatta
    20101 gaaacaagtt cagtatgtac gagtatttga accagtgttt gaatatttac tttaagtaca
    20161 gaaaaagggc agaatataca actgttaact atttaaatta gcagtttata ttctgtcttt
    20221 ttatatggct ttataactta cgtgattttg gtttgataag gaatttatta gtattttcat
    20281 ttacgaattc tgattttaat gcaagcgcca tacttactga tgaataaaag tactaatgat
    20341 taaacaaact atttttaaat ggcaaattga aatagtgcaa attttacact tataaattaa
    20401 tggctataaa ctattttata tctatctatg ttttaactac ttaaattatt agacaaaaca
    20461 attttcttaa attatcaatt aaagtattta aaaatattga tggttaatgt aaaatatcaa
    20521 tataaataag ttttttaaat ttatgtatgt ttatttgatt caaacaaaat aacttaagag
    20581 gagaaagttt atgaaaaaga cactgggatg tttactttta attatgcttt tagtcgtagc
    20641 aggttgttct tttggtggga atcataaatt atcatcaaag aaatcagaag aatcaaaaca
    20701 agaaactgta aaaaaagaat cggaagaaga gaaagatcca gatttagaga aatatgaaga
    20761 aatagagaag aaaatgaaag gaattaaaga tgcgccatct cttgataagt tggatccatt
    20821 aatgacagaa aagtcgttta cgaatagtaa agggattcaa ggatggaaag attacaaaga
    20881 attaatgggt aaagtggaac ttgcagatta tagatttact aaagattcaa aaggatcttc
    20941 aataaaagat gttgatgcat tctttaaagg taagaaaggt ataaaaagga aagtgattga
    21001 aacacacgat gatgtaaaac aagttgatta ttggtatgta gatccagatg gaaagaaaat
    21061 tggcaattca aacacacctg ttttttacgc agaaattatg acaaaatata aagatggaaa
    21121 gttagtttat gcatcagtcg aaccaggatc ttacgtaata cataaagatg atgcaattaa
    21181 atatgacgat tattctaagt taaaaaaatt aagtcagcta actaaacttg atcatccaaa
    21241 accagttcca tatagcgtag ctcaaatcaa atctttcgga gtacctttaa caagcgtttc
    21301 atttatgaca catggatcaa aggatactaa agatgaagtg ttgccggcat tggcctattt
    21361 cactttttca ccaaaaaatt atgaagacaa gtctaatcca gatccaaaag ttttaaattt
    21421 agtacatatg gatttcttaa atgcatctag tgattttggt aacgcacatt ttgttgtttt
    21481 aagtaaatat attaaagagt atgaatcaaa ctatgaaaca gcgtcagatg attctttaaa
    21541 atagtattta ctgtgtgaaa aataaatagt gtactacatt aaataatcgc aataataatc
    21601 ccgataaaca atcagcatta ctgcttatca tatagagttc gtaataacta taactctatg
    21661 attcgcaaat aataaatgat tgtcatcggg atttattttt atcaatttat aaagtgacat
    21721 taccttgttc atcagcaggt ttgaaaacag taatcactgc actaataatt gctaaaatgt
    21781 gtgggatacc tgtccaacag aatattaagt gtagaatacc ttgcatattc ttgccggcat
    21841 aaaatttatg aataccaaaa ctacctaaga acaatgctaa taaaatataa ataactttgt
    21901 ttacttgcat ttctttccct ccagttgaat tgcttataat gtcattagct tctcttttta
    21961 ttatacccac ttttagttca aacattctag tttaagcatt cccaatcatc taaatttcag
    22021 ttattcattc cttacaataa atttaggatt acacttcagt tgcattgtat tattttacgt
    22081 gtgaaatata cgtaatgaat cacatgacaa tcttcaaatt gaaaaatata cattctatga
    22141 tgtaaggtcg catttttaat atatttacgt tataatagtt tgatgaattt tattgaggag
    22201 taagagttat ggcgattaaa aagttagtac cagcatcgca tcctatttta acgaaaaaag
    22261 cgcaagcagt taaaacattt gatgattcgt taaaaagatt attacaagat ttagaagata
    22321 caatgtatgc acaagaagct gctggcttat gtgcacctca aattaatcag tcattgcaag
    22381 tggcaattat tgatatggaa atggaaggat tattacaact tgttaatccg aaaattatta
    22441 gtcaatcaaa tgaaacaata acagacttag aaggttcaat tacattgcca gatgtttacg
    22501 gcgaagtgac aagaagtaaa atgatagttg ttgaaagtta tgacgtcaat gggaacaaag
    22561 ttgaactaac tgcacatgaa gatgtagcaa gaatgatttt gcatattata gatcaaatga
    22621 acggtatccc ttttacagaa cgtgcggacc gtattttaac agataaagaa gtggaggcat
    22681 attttataaa tgactaaaat aatatttatg ggtacaccag acttttcaac aactgtttta
    22741 gaaatgctta ttgcagaaca tgatgtcatt gcagtcgtaa cgcaaccaga tcgacctgtt
    22801 ggacgtaaac gtgttatgac accaccacca gttaaaaaag ttgcaatgaa atatgattta
    22861 cctgtatatc agcctgaaaa attaagtgga tcagaagaat tagaacaatt gcttcaatta
    22921 gatgtagatt taattgtaac tgctgctttt ggacaattat tacctgaatc attgttggca
    22981 ttaccaaaac ttggcgcaat taatgtacat gcatcattgt taccaaagta tagaggtggt
    23041 gcaccaattc atcaggcaat tatcgatggt gaacaagaaa ccggcataac aattatgtat
    23101 atggttaaaa aattagatgc gggtaatatt atttcgcaac aagcaattaa aatagaagaa
    23161 aatgataatg tcggtacgat gcatgataaa ttaagtgtat taggggcaga tttattaaaa
    23221 gaaactttac catctattat agagggcaca aatgaaagtg tacctcaaga tgatacgcaa
    23281 gcaacatttg cttccaatat tcgacgcgaa gatgagcgaa ttagctggaa taaaccagga
    23341 agacaagtgt ttaatcaaat tcgtggatta tcaccatggc cagttgctta tacaactatg
    23401 gatgacacta acttgaaaat atacgatgct gaactcgttg agactaataa gataaacgag
    23461 cctggaacca ttatagaaac gactaaaaaa gccattattg ttgctacaaa tgataatgaa
    23521 gctgttgcaa ttaaagatat gcaattagct gggaaaaaga gaatgttagc tgccaattat
    23581 ttaagtggtg cgcaaaacac actagtaggg aagaaactta tatgatcgaa aacgtgagaa
    23641 gtcttgcttt tgacacgatt caagatatat taaatgaagg tgcgtatagt aacttgcgta
    23701 tcaatgaagt gttgtcagaa aatgaattaa atgcaatgga taaggcttta tttacagaaa
    23761 ttgtctacgg aaccgttaaa agaaaatata cgttagattt ttatttaaag ccttttgtga
    23821 aaacaaagat taaggcatgg gttaggcaat tattatggat gagtatttat caatatgtat
    23881 atttagataa agttccaaat catgccatta ttaatgaagc agttgaaata gcaaaagaac
    23941 gcggtggcta tcataatggt aatgtcgtaa atggtatttt acgtacaatg atgcgtagtg
    24001 acttacctga ttttaatgaa attgcagatc ctaaaaaaag aatggcaatc gagtatagta
    24061 tgccgaagtg gattatagat cattgggcaa cacattatgg tctcgaagaa actgaaacaa
    24121 ttttacagtc atttttagaa acgacatcaa caactgtgcg tgccaacctg acgcgagcat
    24181 cattagatga tattattgaa aagttgcaag acgaaggtta tgacgttgaa aaagatcatg
    24241 acttacctta ttgtctccat ataggaggac aaccaattat tcattctcgt tcatttaaag
    24301 atggattcgt ttcaattcaa gataaaagct caatgtttgt tgcacacatt atgaatgtag
    24361 accgacatga tcacgtatta gatgcatgta gtgcacctgg cggtaaagct tgtcacattg
    24421 ctgaagtttt aatgccagaa gggcaagttg acgcttcaga tatacatgat cacaaaatag
    24481 acttaattaa ttttaatata aaaaaattac gattaacaaa tattaaggct tttcaacatg
    24541 atgcgacaaa accttatgat aaaacatacg ataagatact tgttgatgca ccatgtagcg
    24601 gattaggtgt aatgagacat aagccggaga ttaagtatac tcaaagcaaa caacatattg
    24661 agtcactagt tgaattacag cttgaaatat tggaaaatgt aaaaaacaat gtaaaaatag
    24721 gtggcgaaat catctattca acatgtacaa ttgagcaact agaaaatgaa aacgtgattt
    24781 atacgtttct gaaaaataat aaaaacttcg aatttgaacc gtttcaacat ccgataactg
    24841 gagagttggt caaaacgtta caaatcatgc cgcaagactt taattcagat ggattcttta
    24901 tcactaagat aaaaagaaag gacaattagg aatgataact gctgaaaaga aaaagaagaa
    24961 taaatttctt ccaaattttg acaagcaatc aatatattca ttgcgatttg acgaaatgca
    25021 aaactggctc gttgaacaag gtcaacaaaa atttcgagcg aaacagattt ttgaatggtt
    25081 atatcaaaaa agagtagatt cgattgatga aatgacgaac ttatcgaaag acttacgaca
    25141 gcttttaaaa gataacttta ctgttacaac tttaacaact gtagtaaaac aagaaagtaa
    25201 agacggtaca attaaattct tatttgaatt acaagatggc tatacaattg aaactgtttt
    25261 aatgagacat gattatggaa attcagtatg tgtaacgaca caagtaggtt gtcgtatcgg
    25321 atgtacgttt tgtgcttcta cacttggcgg cttaaaaaga aaccttgaag ctggcgaaat
    25381 tgtttcacaa gttttaacag ttcaaaaagc ccttgatgct acagaagagc gcgtatctca
    25441 aattgtcata atgggtatcg gtgaaccatt tgaaaattat gatgaaatga tggacttttt
    25501 aagaatcgtc aatgatgata acagtttaaa tattggtgca cgtcacatta cagtatcaac
    25561 atcaggtatc attcctagaa tatatgactt tgcggatgaa gatatccaaa ttaattttgc
    25621 tgtaagctta cacgccgcaa aagatgaagt gcgatcacgc ttgatgccaa ttaaccgtgc
    25681 atataatgtt gagaagttaa tcgaagcaat tcaatattat caagaaaaaa caaatcgtcg
    25741 tgttactttt gaatatggtc tgtttggtgg tgtgaatgac caactagaac atgcaagaga
    25801 attagcacat ttaataaaag gcttaaactg ccatgttaac ttaattcctg tcaaccatgt
    25861 tccagaaaga aattatgtga aaacggctaa aaatgatatc tttaaatttg aaaaagaatt
    25921 aaagagacta ggaattaatg ccacaatacg tcgtgaacaa ggttcggata ttgacgcagc
    25981 ttgtggtcaa ttaagagcaa aggaacgaca agtagaaacg aggtaaagac aaatgctaga
    26041 ggcacaattt tttactgata ctggacaaca tagagataag aatgaagatg cgggtggtat
    26101 tttttataat caaactaatc aacaactttt agttctgtgt gatggtatgg gcggccataa
    26161 agcaggagaa gttgcaagta aatttgttac agatgagttg aaatcccgtt ttgaagcgga
    26221 aaatcttata gaagaacatc aagctgaaaa ttggttgcgt aataatataa aagatataaa
    26281 ttttcagtta tatcactatg cacaagaaaa tgcagaatat aaaggtatgg gtacaacatg
    26341 tgtttgtgca cttgtttttg aaaaatcagt tgtgatagca aatgtcggtg attctagagc
    26401 ctatgttatt aatagtagac aaattgaaca aattactagt gatcactcat ttgttaatca
    26461 tcttgtttta acgggtcaaa ttacgccgga agaagcattt acacatccac aacgtaatat
    26521 tattacgaag gtgatgggca cagataaacg tgtgagtcca gatttgttta ttaagcgatt
    26581 aaatttttat gattatttat tattaaattc agatggatta actgattatg ttaaagacaa
    26641 tgaaattaag cgtttgttag taaaagaagg tacaatagaa gatcatggtg atcaattaat
    26701 gcaattggca ttagataacc attcgaaaga taacgttact ttcatactcg cggctattga
    26761 aggtgataaa gtatgatagg taaaataata aatgaacgat ataaaattgt agataagctt
    26821 ggcggcggtg gcatgagtac cgtttatctt gcagaagata cgatacttaa cattaaagtt
    26881 gcaattaagg cgatttttat accacctaga gaaaaagaag aaacattaaa acgttttgaa
    26941 cgagaagtac ataactcatc acagctatca catcaaaata tagtaagtat gatcgatgtt
    27001 gatgaagaag atgactgtta ctacttagta atggaatata ttgaaggtcc gactttgtct
    27061 gagtatattg aaagtcatgg gccattaagt gttgacacgg cgattaattt tacgaatcaa
    27121 atattggatg gcattaaaca tgcgcatgat atgcgtattg tacatagaga tattaagcca
    27181 caaaatatat taattgacag caataaaacg ttgaaaatat ttgattttgg aattgctaaa
    27241 gctttaagtg agacgtcttt aactcagact aatcatgtgt taggtactgt gcagtacttt
    27301 tcgccagaac aagcaaaagg tgaggcaacg gatgaatgta cagatattta ttctataggt
    27361 attgtgttat atgaaatgct tgttggtgaa ccacccttta atggagaaac tgcagttagc
    27421 attgcgatta aacatattca ggattctgtg ccaaatgtga caacagatgt acgtaaggat
    27481 attccgcaat ctttaagtaa tgtcatttta cgcgctacag aaaaagacaa agcgaatcgt
    27541 tacaaaacaa ttcaagaaat gaaagatgat ttgagtagtg ttttacatga aaatcgagcg
    27601 aatgaagatg tctatgaact cgataaaatg aaaacgatag cggtaccttt gaaaaaagaa
    27661 gatctagcaa agcatattag tgaacataag tcgaatcaac ctaaacgtga aacgacgcaa
    27721 gtacctattg taaatgggcc tgctcatcat cagcaattcc aaaagccaga aggtacggtg
    27781 tacgaaccaa aacctaaaaa gaaatcaaca cgaaagattg tgctcttatc actaatcttt
    27841 tcgttgttaa tgattgcact tgtttctttt gtggcaatgg caatgtttgg taataaatac
    27901 gaagagacac ctgatgtaat cgggaaatct gtaaaagaag cagagcaaat attcaataaa
    27961 aacaacctga aattgggtaa aatttctaga agttatagtg ataaatatcc tgaaaatgaa
    28021 attattaaga caactcctaa tactggtgaa cgtgttgaac gtggtgacag tgttgatgtt
    28081 gttatatcaa agggccctga aaaggttaaa atgccaaatg tcattggttt acctaaggag
    28141 gaagcattgc agaaattaaa atcgttaggt cttaaagatg ttacgattga aaaagtatat
    28201 aataatcaag cgccaaaagg atacattgca aatcaaagtg taaccgcaaa tactgaaatc
    28261 gctattcatg attctaatat taaactatat gaatctttag gcattaagca agtttatgta
    28321 gaagactttg agcataaatc ctttagcaaa gctaaaaaag ccttagaaga aaaagggttt
    28381 aaagttgaaa gtaaggaaga gtatagtgac gatattgatg agggtgatgt gatttctcaa
    28441 tctcctaaag gaaaatcagt agatgagggg tcaacgattt catttgttgt ttctaaaggt
    28501 aaaaaaagtg actcatcaga tgtcaaaacg acaactgaat cggtagatgt accatacact
    28561 ggtaaaaatg ataagtcaca aaaagttaaa gtttatatta aagataaaga taatgacggt
    28621 tcaactgaaa aaggtagttt cgacattact agtgatcaac gtatagacat tcctttaaga
    28681 attgaaaaag gaaaaacagc aagttatatt gttaaagttg acggtaaaac tgtagctgaa
    28741 aaagaagtca gctatgatga tatttaaata taattgaagt aaatgtaccg aggtttctat
    28801 ttggaagtct cggtattttt atgttgagat tgcggtagtt ttaaaatgct taatgtcatc
    28861 atttacagtt gagcattgtc tatcaattct gtatcactct cacaatattt atatcatttg
    28921 aaatgatcat ttatatatta attttccagt ctttgatata ataaatgcag taaaattaat
    28981 cgagaggtgc cattttgaag acaggtcgaa tagtgaaatc aattagtggg gtatatcaag
    29041 tagacgttaa tggcgaacgt ttcaatacaa aaccacgagg attatttaga aagaaaaaat
    29101 tttcaccggt agttggtgat atagtggaat ttgaagtaca aaacattaac gaaggctata
    29161 ttcatcaagt gtttgagcgg aaaaatgagt tgaaaagacc acctgtaagt aatatagata
    29221 cactagtaat tgtaatgagt gctgtcgagc caaatttttc aacgcaatta ttagatcgat
    29281 ttttagttat tgcacattcg tatcagttaa atgcgagagt tttggtgact aaaaaagata
    29341 aaacaccaat tgaaaagcag ttcgaaatta atgagttgtt gaaaatatat gaaaatattg
    29401 gctatgagac tgaatttatt ggaaatgatg atgatcgaaa aaaaattgta gaagcttggc
    29461 cagctggact tatagtactt agtggtcaat caggtgtcgg taagtccact ttcttaaatc
    29521 attatcgtcc agaacttaat cttgagacaa atgatatatc aaaatcatta aatcgaggaa
    29581 agcatactac aagacatgtc gaactattcg aacgtcaaaa cggttatatt gcagacacac
    29641 ctggattcag tgctttagat tttgatcata tagataaaga tgaaataaaa gattattttc
    29701 ttgaattaaa tcgatatggt gaaacatgta agtttaggaa ttgtaatcat atcaaagaac
    29761 ctaattgtaa tgttaagcat caattagaga tagggaatat tgcgcaattt agatacgacc
    29821 attatttaca actatttaat gaaatttcaa atagaaaggt tagatattaa atgacaaaac
    29881 tatatccatc attattatct gttgattttt tggatttaca acatgaatta aaacgacttg
    29941 aagaagcagg tgtcgacgga gttcattttg atgttatgga tggtcaattt gtgcctaata
    30001 tatctattgg tttaccaata ttagatgcag taagaaaagg cacaacatta cctatagacg
    30061 tacatttgat gattgaaaat ccagaaaagt atattgcatc atttgcagaa catggtgccg
    30121 atatgatttc aattcatgtc gaatcaacgc ctcatattca tcgtgctatt caaatgatta
    30181 aacatttaga taaaaaagct ggtgtagtaa ttaatcctgg tacaccaata tcacaaattg
    30241 aacctatttt agacattgtt gattatgtat tagtgatgac agttaaccca gggtttggtg
    30301 gtcaatcatt tattgatcaa tgcgtagaaa aaatagcggg tcttaatgct attaaaatgg
    30361 aacgtcaatt aaactttgat attgaagttg atggaggcgt aaataccgat acagcgaaag
    30421 tttgtgttga aaatggtgct acaatgctag taacaggttc atttttcttt aaacaagaag
    30481 attataaaaa agtcacacaa gcattgaaag gttgagtgta tatgcatata aatttattat
    30541 gttctaatcg acacttgccg caagatattt gggccaaaag taatgaaggt aaatggggcg
    30601 gcgttgatag aggtgctttg attttattga agcatcaaat tatccctttt ttctcagtgg
    30661 gagactttga ttcagtcagt aaagaagaac gccaacttct aacagaacag ttacaaatca
    30721 aaccagttca agctgaaaaa gctgatacgg atttagcttt agcggttgat aaagctgttg
    30781 cacttggatt tgatagtatt acaatttatg gtgcaacagg cggacgatta gatcactttt
    30841 ttggggcaat tcagttatta ttgaaaaaag catattataa acatgatgtt catatagaag
    30901 ttatcgatca acaaaataaa attgaattat tgcctaaagg tcaacataca gttgaaaaag
    30961 ataagagtta tccgtacatt tcatttatac cgatgactga tgatgtagaa ctttctctag
    31021 caggttttaa atataattta gctagacaaa tgcttaatat aggttctact ttaactattt
    31081 caaatgaaat tgagtctttg caagcgaaag taactgtaca tgatgggttg attttgcaaa
    31141 ttagaagtac agatttaaat taagtatatt caaatttgtg aggattttta ataaagtgca
    31201 tgtgttattt aataaagtga cgtttataga tagaatttat aacataataa tagatgaatc
    31261 acgctgtaat taatgaagat tatggcgtga tttattattg gaaggaaaat tgtaggtcct
    31321 agtacattga tttatgtgcc aaaatcgata ttgaacccat aagtccaatt tgacagagaa
    31381 ccattattaa acgtattaac caaattatat tgatagttcg aatttcacta tgaaccatta
    31441 tgtattgttt ggtaacaaaa aaagaactaa gaggttgagc tcttagttct taagtaaatg
    31501 tgtcctccac ataaggtcac attttttatg tgcaatatat ttattaaact ctagttactt
    31561 taccagattt taaagcacgt gcagaaaccc aaactttttt aggtttaccg tcaactagga
    31621 ttctaacttt ttgaaggtta gcgttccatc tacgtttagt agagtttaaa gcgtgtgaac
    31681 gtctgttacc agtcgaagct ttacgacctg ttacgaaaca ttgtttaccc atatgagtac
    31741 ctcctttaat aaatataaat acacataact acttatatac ttaattaaga tagcatagtt
    31801 tcatttgaaa aacaatgaat aattttcaca taaaagtcaa aaatactgag ttttgtgata
    31861 taattgtaga ctgtgaagtt atgtagtatg atattttaga gaaataagtg aatgaaacat
    31921 ttaaaatttt tatttaatga tactacatct attaaaagaa aacgcctata gataatcgtc
    31981 atgagtgtaa attcagttta ctcaaaatat aataggtgat ttaagcgtaa gtcattctga
    32041 taagttgtac cattgatatt ttataaaaat aatcaatgaa acttaaagcg tttatgacta
    32101 cactaagtgg taaaatttta aaagtgatta gggaaaacga ataataaact ttgaaattta
    32161 ggagggacaa agatatgaca ttagagattt caaatgatta cggtaaaatt gatatttcaa
    32221 acgaagtgat tgcttcggtt gtaggtggaa aggccgttga atgttatggt attgtaggta
    32281 tggcatctag acaacaagtt agagatggta ttgcggaaat actaggacat gaaaattatg
    32341 ctaaaggcat caaagtaact gaaaataatg gcgtagtgga tatagatatg tacattattg
    32401 taagttatgg tgtgaaaata tctgaagttg ccaataatgt acaatcaaca gtgaaatata
    32461 ctttggaaaa atcacttaat gtatcagtaa attcaatcaa tatatatgta caaggtgtac
    32521 gtgtgaataa tacaggcaag aaagcttagg aggacaactt gaaatgatta gcaaaattaa
    32581 tggtaaatta tttgccgata tgattataca aggggcacaa aatttatcta acaatgcaga
    32641 tttggtagat tctttgaatg tgtatccagt gccagatggt gatacaggaa caaatatgaa
    32701 tcttactatg acttcaggtc gcgaagaagt agagaataat ttgtcgaaaa atatcggcga
    32761 attaggtaaa acattctcga aaggtttact aatgggtgca agaggtaact ctggtgtcat
    32821 cttgtcacaa ttattcagag gattttgtaa aaatattgaa agtgaatctg aaattaattc
    32881 aaaattgtta gctgaaagtt ttcaagctgg tgttgaaacg gcatataaag ctgttatgaa
    32941 accagttgaa ggtacaatac ttacagttgc aaaagatgct gcgcaagctg caatagaaaa
    33001 agcaaataat actgaagatt gtatagaatt aatggagtac attattgtaa aagccaatga
    33061 atcacttgaa aacacaccaa acttattagc tgtacttaaa gaagttggtg ttgttgatag
    33121 tggcggtaaa ggtttgttat gcgtttacga aggattctta aaagcgctta aaggtgaaaa
    33181 agttgaagcc aaagttgcaa agatagataa agatgaattt gtacatgatg aacatgattt
    33241 ccatggtgta attaatactg aagatattat ttatggctat tgtactgaaa tgatggttcg
    33301 ttttggaaag aataaaaaag cctttgatga acaagaattc aggcaagata tgagtcaatt
    33361 tggtgattct ttattagtca ttaatgatga agaaattgtg aaagttcacg tgcataccga
    33421 atacccaggt aaagtgttta attatggtca acaatatggt gaattaatta aacttaaggt
    33481 tgaaaatatg agagaacagc accgtgaagt gattcgaaaa gaacagcaca cagctaaacc
    33541 gaaaatggaa acggttgaaa cagcaattat tactatttct atgggtgaag gtatttcaga
    33601 gatattcaaa tcaatgggtg ccacacatat cattagtggt ggacaaacga tgaatccttc
    33661 tacagaagat atcgttaaag tcattgaaca atcaaaatgt aaacgtgcaa ttattttacc
    33721 gaataataaa aatattttaa tggcaagtga acaagcagcg agtattgttg atgcagaagc
    33781 agttgttatt ccaacgaaat ctattcctca aggtataagc gcactattcc aatatgatgt
    33841 ggacgcaaca cttgaagaaa ataaagcgca aatggctgat tcagtaaata acgttaaatc
    33901 tggttcatta acgtacgctg ttcgtgatac gaaaattgat ggcgttgaga ttaaaaaaga
    33961 cgcgtttatg ggcttgattg aagataagat tgtaagcagc caaagtgatc aattaacaac
    34021 ggttactgag ttgttaaatg agatgttagc agaagatagt gaaatattga ctgtgattat
    34081 tggtcaagat gcagagcaag cagttacaga taacatgata aactggatcg aagagcaata
    34141 tccagatgta gaagtggaag ttcatgaagg tggacaacca atttatcaat atttcttttc
    34201 agtagaataa aaatttaaaa taaaaaacta ccaatgataa atcatcagtt ggtagttttt
    34261 tattttgcta ttttagtgtt attgcgggtt aaaagtatca ttctcgagtt gctaacaatg
    34321 tcatgttcaa cttagtcatg ataaaataaa taacatacta aatgatacgt aaaatcaaat
    34381 aaaacatagg tgatttattt tggctaaagt aaacttaata gaaagtccat attctctttt
    34441 acaattaaaa ggtataggtc ctaagaaaat agaagtattg caacaactaa atattcatac
    34501 agtggaagat cttgttcttt atttgccaac tagatatgaa gataatacag tgattgattt
    34561 gaatcaagca gaagatcaat ctaacgttac gatagaagga caagtatata cagctccagt
    34621 agttgcattt tttggaagaa ataaatcaaa attaaccgtt catttaatgg taaataatat
    34681 tgctgtcaaa tgtatttttt tcaatcaacc gtatttaaaa aagaaaatcg aattaaatca
    34741 aactataact gttaaaggta agtggaatag agttaaacag gaaattactg gtaatagggt
    34801 tttctttaat tcacaaggga cacaaactca agaaaacgca gatgttcaat tagaaccagt
    34861 ctatcgtatt aaggaaggta ttaaacaaaa gcaaatacga gaccaaatta gacaagcgtt
    34921 aaatgatgtg acaattcatg aatggttaac tgatgaacta agagaaaaat ataaattaga
    34981 gaccttggac tttactttga acacattaca tcatcctaaa agtaaagagg atttattacg
    35041 tgctcgtaga acctatgcat ttactgaact gtttttattc gaattacgta tgcaatggct
    35101 aaatagatta gaaaagtcat ctgacgaagc aattgaaatt gattatgact tagaccaagt
    35161 taaatcattt attgatcgtt taccttttga actaactgaa gcacagaaat ccagtgttaa
    35221 tgaaattttt agagatttaa aagcaccaat acgtatgcat cgattacttc aaggtgatgt
    35281 aggttcagga aaaacagtag ttgctgcaat ttgtatgtat gcgttaaaaa cggctggtta
    35341 tcaatcagca ttgatggtac caactgaaat tttagcagag caacatgctg aaagtttaat
    35401 ggctttattt ggagattcta tgaacgttgc attgttaact gggtcagtaa aaggtaagaa
    35461 acgaaagata cttttagaac aacttgaaaa tggtacgatt gattgtttaa ttggaaccca
    35521 tgctttgatt caagatgatg tgattttcca taatgttggt ttagtaatta cagatgaaca
    35581 acatcgattt ggtgtgaatc aacgccagct tttaagagaa aaaggtgcaa tgacgaatgt
    35641 gttatttatg acagcaacgc cgataccaag aacactagca atatcagttt ttggtgagat
    35701 ggatgtgtct tcaattaaac aattaccaaa aggtcgtaaa cctatcatta ctacttgggc
    35761 aaagcatgag caatacgata aagttttgat gcaaatgacc tcagagttga aaaaaggtcg
    35821 tcaagcatat gtcatttgcc cgctaataga aagttctgag catctcgaag atgttcaaaa
    35881 tgttgtcgca ttgtacgagt ctttacaaca gtattatggt gtttcccgtg tagggttatt
    35941 gcatggtaag ttatctgccg atgaaaaaga tgaggtcatg caaaagttta gtaatcatga
    36001 gatagatgtt ttagtttcta ctactgttgt tgaagtaggt gttaatgtac cgaatgcaac
    36061 ttttatgatg atttatgatg cggatcgctt tggattatca actttacatc agttacgcgg
    36121 tcgtgtaggt agaagtgacc agcaaagtta ctgtgtttta attgcatccc ctaaaacaga
    36181 aacaggaatt gaaagaatga caattatgac acaaacaacg gatggatttg aattgagtga
    36241 acgagactta gaaatgcgtg gtcctggaga tttctttggt gttaaacaaa gtgggttgcc
    36301 agatttctta gttgccaatt tagttgaaga ttatcgtatg ttagaagttg ctcgtgatga
    36361 agcagctgaa cttattcaat ctggcgtatt ctttgaaaat acgtatcaac atttacgtca
    36421 ttttgttgaa gaaaatttat tacatcgcag ttttgactaa ttaccatgct gatttgtcaa
    36481 tttgagtgca acacttcgtt aattgagtga tatgacactt gaactattta aatgtaaagt
    36541 ggtattttaa caatttataa atttccgact aaataatagc taaataatac agttatttgt
    36601 tgagtcggtt aaatagaaag tgttatgata tgtgaggaat gtttaagact aggtactaaa
    36661 aaatgagggg tgagacgttg aaactaaaga aagataaacg tagagaagca atcagacaac
    36721 aaattgatag caatcccttc atcacagacc atgaactaag cgacttattt caagtgagta
    36781 tacaaacaat tcgtttagat cgcacttatt taaacatacc agaattaagg aagcgtatta
    36841 aattagttgc tgaaaagaat tatgaccaaa taagttctat tgaagaacaa gaatttattg
    36901 gtgatttgat tcaagtcaat ccaaatgtta aagcgcaatc aattttagat attacatcgg
    36961 attctgtttt tcataaaact ggaattgcgc gtggtcatgt gctgtttgct caggcaaatt
    37021 cgttatgtgt tgcgctaatt aagcaaccaa cagttttaac tcatgagagt agcattcaat
    37081 ttattgaaaa agtaaaatta aatgatacgg taagagcaga agcacgagtt gtaaatcaaa
    37141 ctgcaaaaca ttattacgtc gaagtaaagt catatgttaa acatacatta gttttcaaag
    37201 gaaattttaa aatgttttat gataagcgag gataaaatta tggttaaatt agcaattgat
    37261 atgatgggtg gcgacaatgc gcctgatatc gtattagaag ccgtacaaaa ggctgttgaa
    37321 gactttaaaa atctagaaat tatgcttttc ggtgacgaaa aaaagtataa tctgaaccat
    37381 gaacgaatcg aatttagaca ttgttctgaa aagattgaaa tggaagatga gcctgttaga
    37441 gcgattaaac gtaaaaaaga tagctcaatg gtaaaaatgg ctgaagctgt gaaatctggt
    37501 gaagcagatg gatgtgtgtc agcaggtaat actggtgctt taatgtcagt tggtttattc
    37561 attgttggac gtattaaagg tgtagctaga ccggctttag tagtaacatt gccaacgatt
    37621 gatggaaaag gttttgtctt tttagacgtt ggtgcaaatg ctgatgctaa acctgaacac
    37681 ttattacagt atgcgcaact aggggatatt tatgctcaaa aaattagagg tattgataat
    37741 ccgaaaatct cattattaaa tataggtacc gagccagcta aaggtaatag tttaacgaaa
    37801 aaatcatttg agttattaaa tcaagatcat tcattgaatt ttgttgggaa tattgaagcg
    37861 aagacattaa tggatggcga tacagatgtt gtagttaccg atggctatac tgggaacatg
    37921 gtccttaaaa atttagaagg tactgcaaaa tcaatcggta aaatgttaaa agatacgatt
    37981 atgagtagta ctaaaaataa attagcaggt gcaatattga agaaagattt agcagaattc
    38041 gctaaaaaga tggattactc agaatacggt ggttcagtat tattaggatt ggaaggtact
    38101 gtagttaaag cacacggtag ttcaaatgct aaagcttttt attctgcaat tagacaagcg
    38161 aaaatcgcag gagaacaaaa tattgtacaa acaatgaaag agactgtagg tgaatcaaat
    38221 gagtaaaaca gcaattattt ttccgggaca aggtgcccaa aaagttggta tggcacaaga
    38281 tttgtttaat aacaatgatc aagcaactga aattttaact tcagcagcaa agacgttaga
    38341 ctttgatatt ttagagacaa tgtttactga tgaagaaggt aaattgggtg aaactgaaaa
    38401 cacgcaacca gctttattga cgcatagttc ggcattatta gcagcgctaa aaaatttgaa
    38461 tcctgatttt actatggggc atagtttagg tgaatattca agtttagttg cagctgacgt
    38521 attatcattt gaagatgcag ttaaaattgt tagaaaacgt ggtcaattaa tggcgcaagc
    38581 atttcctact ggtgtaggaa gcatggctgc agtattggga ttagattttg ataaagtcga
    38641 tgaaatttgt aagtcattat catctgatga caaaataatt gaaccagcaa acattaattg
    38701 cccaggtcaa attgttgttt caggtcacaa agctttaatt gatgagctag tagaaaaagg
    38761 taaatcatta ggtgcaaaac gtgtcatgcc tttagcagta tctggaccat tccattcatc
    38821 gctaatgaaa gtgattgaag aagatttttc aagttacatt aatcaatttg aatggcgtga
    38881 tgctaagttt cctgtagttc aaaatgtaaa tgcgcaaggt gaaactgaca aagaagtaat
    38941 taaatctaat atggtcaagc aattatattc accagtacaa ttcattaact caacagaatg
    39001 gctaatagac caaggtgttg atcattttat tgaaattggt cctggaaaag ttttatctgg
    39061 cttaattaaa aaaataaata gagatgttaa gttaacatca attcaaactt tagaagatgt
    39121 gaaaggatgg aatgaaaatg actaagagtg ctttagtaac aggtgcatca agaggaattg
    39181 gacgtagtat tgcgttacaa ttagcagaag aaggatataa tgtagcagta aactatgcag
    39241 gcagcaaaga gaaagctgaa gcagtagtcg aagaaatcaa agctaaaggt gttgacagtt
    39301 ttgcgattca agcaaatgtt gccgatgctg atgaagttaa agcaatgatt aaagaagtag
    39361 ttagccaatt tggttcttta gatgttttag taaataatgc aggtattact cgcgataatt
    39421 tattaatgcg tatgaaagaa caagagtggg atgatgttat tgacacaaac ttaaaaggtg
    39481 tatttaactg tatccaaaaa gcaacaccac aaatgttaag acaacgtagt ggtgctatca
    39541 tcaatttatc aagtgttgtt ggagcagtag gtaatccggg acaagcaaac tatgttgcaa
    39601 caaaagcagg tgttattggt ttaactaaat ctgcggcgcg tgaattagca tctcgtggta
    39661 tcactgtaaa tgcagttgca cctggtttta ttgtttctga tatgacagat gctttaagtg
    39721 atgagcttaa agaacaaatg ttgactcaaa ttccgttagc acgttttggt caagacacag
    39781 atattgctaa tacagtagcg ttcttagcat cagacaaagc aaaatatatt acaggtcaaa
    39841 caatccatgt aaatggtgga atgtacatgt aatatatttg agctaaagct cattgacgca
    39901 gtggttgact ggtcatccaa tggagaattg tctgacctag tcaactttgc gggggaaatt
    39961 ctaagcaacc tagataaggt tccagaattt ctccctaaga aacactaatc aataaattga
    40021 taagaagatt agaggaacgc ttgagctaaa gctcaagata aagacgcaga aatcaataaa
    40081 ttgataactg ggatagaggt acgcctgagc taaagctcaa gataaagacg cagtaatcaa
    40141 taaattgata actgggatag aggtacacct gagctaaagc tcatgcataa gaaacactaa
    40201 tcaataaatt gataagtgtt tctaaaattt ctacttgttt tttagaattt aaaatgggaa
    40261 aatataatag tctatgtata ggcattttta aaggaggtga atcgacgtgg aaaatttcga
    40321 taaagtaaaa gatatcatcg ttgaccgttt aggtgtagac gctgataaag taactgaaga
    40381 tgcatctttc aaagatgatt taggcgctga ctcacttgat atcgctgaat tagtaatgga
    40441 attagaagac gagtttggta ctgaaattcc tgatgaagaa gctgaaaaaa tcaacactgt
    40501 tggtgatgct gttaaattta ttaacagtct tgaaaaataa taaatcttac atctgggtcg
    40561 tcagtattgt cgactcagtt tttttcttta attatcaata gttttaacgt aaaattaaag
    40621 atgattcaag agcaacacat aaaggagata aaataatgtc taaacaaaag aaaagtgaga
    40681 tagttaatcg ttttagaaag cgctttgata ctaaaatgac agagttaggc tttacttatc
    40741 aaaatattga tttataccaa caagcatttt cgcattcgag ttttattaat gattttaata
    40801 tgaatcgttt agaccataat gagcgtttag agtttttggg tgatgcggta ttagaattga
    40861 cggtttcacg atatttattt gataaacatc ccaacttgcc agaagggaat ttaacaaaaa
    40921 tgcgtgccac tattgtatgt gagccctcac ttgtaatatt tgcgaataaa attggattga
    40981 acgaaatgat tttacttggt aaaggtgaag agaaaacagg gggacgtaca agaccatcat
    41041 taatatcaga tgcattcgaa gcatttattg gggcattgta tttggatcaa ggactagata
    41101 tagtttggaa atttgctgag aaagttattt tcccacatgt agaacaaaat gagttattag
    41161 gcgtggtaga ttttaaaaca caattccaag aatatgtgca ccagcaaaat aaaggtgatg
    41221 taacctataa tttaataaaa gaagagggac cggcacatca tcgtctattc acttcagaag
    41281 ttattctgca aggggaagca atagctgaag gtaaagggaa aacgaaaaaa gaatcagaac
    41341 aacgtgctgc tgaaagtgcc tataagcaat taaaacaaat taaatagaaa tttatatgat
    41401 acgacatata ggtgttcgat ttaggattta aggaagaatt tttaatattt tatggaacaa
    41461 cttcgaaatt taatatacaa atattaaaat atcgtataca tgtgttcttt aaaattgtga
    41521 taaggagttt aggatggttt atttaaaatc aatagatgcc attggattta agtcttttgc
    41581 agatcaaacc aatgttcaat tcgataaagg tgtaactgca attgttggtc caaatggaag
    41641 cggtaaaagt aatattacag atgctattaa atgggtgttg ggtgaacaat cggctaaatc
    41701 attacgtggc tcaaaaatgg aagatattat cttctcaggt gcagaacatc gcaaagctca
    41761 aaattatgct gaagtacagt taagattaga taatcattct aaaaagctca gtgttgatga
    41821 aaacgaagtt attgtaacaa gaagattgta tcgaagtggt gaaagtgagt actacataaa
    41881 taatgaccgt gcaagattaa aagatattgc cgatttattt ttagattctg gattgggaaa
    41941 agaagcgtat agcattatct cgcaaggtag agttgatgaa atactaaatg ctaaaccaat
    42001 tgatagacgt caaattattg aagaatcggc tggtgtactt aaatataaaa aacgtaaggc
    42061 tgaatcatta aataaacttg accaaacaga agataattta acgagagtag aagacatttt
    42121 atatgatttg gaaggtcgcg tagaacctct aaaagaggag gcagctatag ctaaagaata
    42181 taagacactt tcacatcaaa tgaaacatag tgacattgta gttacagtgc acgatattga
    42241 tcaatataca aatgacaata gacaattaga tcaacgttta aatgatttac aaggtcaaca
    42301 agcaaataaa gaagctgaca agcaacgttt aagccaacaa attcaacaat ataaaggtaa
    42361 acgacatcaa cttgataacg atgttgaatc gcttaattat caattagtaa aagctacgga
    42421 agcctttgaa aaatatacgg gacaattaaa tgttttagaa gaacgtaaga aaaatcaatc
    42481 tgaaacaaat gcacgatatg aagaagaaca agaaaattta atggagcttt tagaaaatat
    42541 atcaaatgag atttctgaag ctcaagatac ttataagtct ctgaaaagta aacaaaaaga
    42601 actcaatgct gtcattcgtg aacttgaaga acaactatat gtttcagacg aagcacatga
    42661 tgaaaaattg gaagaaatta aaaacgaata ctatacatta atgtcagagc aatcagatgt
    42721 taacaacgat attcgttttt taaagcatac tatagaagag aatgaggcta aaaaatcaag
    42781 actagattct cgattagttg aagtttttga gcaattgaaa gatattcagg gtcaaataaa
    42841 aacgacaaaa aaagaatatc aacagaccaa caaagaactt tctgctgtag ataaagaaat
    42901 taaaaatata gaaaaagatc tcactgatac aaaaaaagca caaaatgaat acgaagagaa
    42961 attgtatcaa gcatatcgat ataccgaaaa aatgaaaaca cgtattgata gtttggcaac
    43021 gcaagaggaa gaatacactt attttttcaa tggcgtcaaa catattttga aagctaaaaa
    43081 taaagaatta aagggtattc atggtgcagt tgcggaaatt attgatgtgc catctaaatt
    43141 aactcaggca attgaaacag cattaggtgc ttcattacaa catgtcattg tagattcaga
    43201 aaaagatgga cgccaggcta ttcaattttt aaaagaacgt aatttaggtc gtgcgacgtt
    43261 tttaccatta aatgttatac agagtagagt ggtagcgact gatattaaat ctattgctaa
    43321 agaggcaaac ggatttatta gtattgcttc ggaagcagtg aaagtagcac cagaatatca
    43381 aaatattatc gggaatttat taggtaatac gattatcgtt gatcatttaa agcatgcaaa
    43441 tgaattggca cgtgcgatta aatatcgaac tcgtattgtt actttggaag gtgatattgt
    43501 aaaccctggt ggttctatga ctggtggtgg cgctcgtaag tccaaaagta ttctgtctca
    43561 aaaagacgag ttgacaacaa tgagacacca attagaagat tacttgcgtc aaacagaatc
    43621 atttgaacaa caatttaaag agttgaagat aaaaagtgat caattaagtg aactgtattt
    43681 tgaaaaaagt caaaagcata atacacttaa agagcaagtg catcattttg aaatggagct
    43741 cgatagatta actacacaag aaacacaaat aaaaaatgat catgaagaat tcgaatttga
    43801 aaaaaatgat ggttatacga gtgacaaaag tcgacaaact ttgagtgaaa aagaaactca
    43861 tttagaaagt attaaagcat ctttaaaacg actagaagat gaaattgaac gctacacaaa
    43921 actttctaaa gaaggtaagg aaagcgtaac taaaacacaa caaacgttac atcagaaaca
    43981 atctgatctt gctgtggtta aagagcgtat taaaacacaa caacagacaa tagatcgatt
    44041 aaataatcaa agtcaacaaa ctaaacatca attaaaagat gttaaagaaa aaattgcatt
    44101 ctttaattcg gatgaagtga tgggcgaaca agcttttcaa aatattaaag atcaaattaa
    44161 tggtcaacaa gaaacgagaa cacgcttatc tgatgaatta gataaattga aacaacaacg
    44221 tattgagttg aatgaacaaa tcgatgcgca ggaagctaca ctacaagttt gtcaccaaga
    44281 tattttagct atcgaaaatc actaccaaga tattaaagct gaacaatcaa agttagatgt
    44341 attaattcat catgcgatag atcatttaaa tgatgaatat caattgactg ttgaacgtgc
    44401 gaaatctgaa tatacgagtg atgaatcgat tgacgcatta cgtaaaaaag ttaagttaat
    44461 gaagatgtcg attgatgaac taggtcctgt aaacttaaat gcaattgaac aatttgaaga
    44521 gttaaatgaa cgttatacat ttttaagtga acaacgtaca gatcttcgta aagctaaaga
    44581 aacattagag caaattataa gtgaaatgga tcaagaggtt actgaaagat ttaaagaaac
    44641 tttccatgct attcaaggac attttacagc tgtgttcaaa caattgtttg gtggaggcga
    44701 tgcagaattg caattaactg aagccgatta tttaacagct ggtattgata ttgtggtaca
    44761 accaccgggt aaaaagttgc aacatttatc gttactgagt ggtggtgagc gtgcattaac
    44821 tgctattgct ttactatttg caattttaaa agtaagatct gcaccttttg ttatattaga
    44881 tgaggttgaa gctgcactag atgaagcaaa tgttattaga tacgcaaaat atttaaatga
    44941 gttatcagac gaaacacaat tcattgttat tacacaccgt aaaggaacaa tggaatttgc
    45001 agataggtta tacggtgtaa caatgcaaga atcaggtgtt actaaacttg tgagtgtgaa
    45061 tttaaataca atagatgatg tgttgaagga ggagcaataa tgagcttttt taaacgctta
    45121 aaagataagt ttgcaacaaa taaagaaaat gaagaagtta aatccttaag agaagaacaa
    45181 ggtcaagaca aattagaaga tacacattct gaaggttcaa cgcaggacgt aaatgattta
    45241 gcagaaaatg ctgaagtgaa aaagaagcca cgcaagttga gtgaagcgga ttttgatgac
    45301 gatggcttaa tatcaattga agattttgaa gaaattgaag ctcaaaaaat gggtgctaaa
    45361 tttaaagcag gactcgaaaa atctcgtcaa aatttccaag aacaattaaa taatttgata
    45421 gcgagatatc gtaaagtaga tgaagacttt tttgaagctt tagaagaaat gttaatcact
    45481 gcagacgtcg gttttaatac agtgatgacg ttaactgaag aattacgtat ggaagcacaa
    45541 cgacgtaata ttcaagatac tgaagatttg cgtgaagtca ttgttgaaaa aatcgtagag
    45601 atttaccatc aagaagatga taattcagaa gctatgaaca tagaagatgg tcgtttaaat
    45661 gtcattttaa tggtcggtgt gaatggtgtt ggtaaaacaa caacaattgg aaaattagct
    45721 taccgatata aaatggaagg taaaaaagta atgttagctg cgggcgatac ttttagagcg
    45781 ggtgctattg atcaattgaa agtttggggc gaacgtgttg gtgtagatgt aattagccaa
    45841 agtgaaggtt ctgatccagc tgctgttatg tatgatgcga ttaatgccgc taaaaacaaa
    45901 ggtgttgata ttttaatctg tgataccgct ggacgtttac aaaataaaac aaatctaatg
    45961 caagaattag aaaaagttaa gcgtgtaatt aatcgagcag tgccagatgc gcctcatgaa
    46021 gcattactat gtttagatgc tacaactggt cagaatgcgt tgtcacaagc tagaaacttt
    46081 aaagaagtaa caaatgttac aggtattgta ttaacgaaat tagatggtac agccaaaggt
    46141 ggtatcgtat tagccattcg taatgaattg cacattccag ttaaatatgt aggtttaggt
    46201 gagcaattag atgacttaca accatttaac cctgaaagtt atgtctacgg cttattcgct
    46261 gatatgattg aacaaaatga cgaaataaca acagttgaaa atgatcaaat tgtaacagaa
    46321 gaaaaggacg ataatcatgg ggcaaaatga tttagttaaa acgttacgaa tgaattattt
    46381 gtttgatttt tatcaatcct tattgacgaa taaacaacgt aattatttgg aattatttta
    46441 tctcgaagat tattctttaa gtgaaatcgc agatactttt aatgtgagta gacaagcagt
    46501 ttatgataat ataagaagaa ctggcgattt agttgaagat tatgaaaaga aattggaatt
    46561 ataccagaaa tttgagcaac gccgagaaat atatgatgaa atgaaacaac atttaagtaa
    46621 tccagaacaa atacaacgtt atattcaaca attagaagac ttagaataga tataaattga
    46681 gggaggacat cgatatggca tttgaaggct tatcagaacg cctgcaagcg acgatgcaaa
    46741 aaatgcgtgg taagggtaaa cttactgaag ctgatataaa gataatgatg cgtgaagtaa
    46801 gattagcgtt atttgaggct gacgtaaact ttaaagtggt aaaagaattt attaaaacag
    46861 tatcagaacg cgcattaggt tccgatgtaa tgcaatcatt aacaccaggg caacaagtta
    46921 ttaaaatagt tcaagatgaa ttaacgaagt tgatgggtgg agaaaataca tcgattaata
    46981 tgtcaaataa accacctact gttgttatga tggttggttt acaaggtgct ggtaaaacaa
    47041 caactgcagg taaattagca ttattgatgc gtaaaaaata caacaaaaaa cctatgttag
    47101 ttgcagcaga tatttatcgt ccagcagcga taaatcaatt acaaacagta gggaaacaaa
    47161 ttgatattcc tgtatacagt gaaggagatc aagtaaagcc acaacaaatt gtaactaatg
    47221 cattaaaaca tgctaaagaa gaacatttag actttgtaat cattgataca gcaggtcgat
    47281 tacacatcga tgaagcattg atgaacgaat taaaagaagt aaaagaaatt gctaaaccaa
    47341 acgaaattat gttagttgtc gattcaatga cgggtcaaga tgctgtcaat gttgcagaat
    47401 cttttgacga tcaacttgat gtcacaggtg ttaccttaac taaattagat ggtgatacac
    47461 gtggtggtgc agctttatct attcgttcgg tgacacaaaa accaattaaa tttgttggta
    47521 tgagtgaaaa gttagatggt ttagagctat tccatcctga acgtatggca tcacgtattt
    47581 taggtatggg tgatgtgtta agtttaattg aaaaagcgca acaagatgtg gatcaagaaa
    47641 aagcaaaaga tttagagaaa aagatgcgtg agtcatcgtt tactttagat gattttttag
    47701 aacaacttga tcaggtgaaa aatctaggac cactggatga tattatgaaa atgattccag
    47761 gtatgaataa aatgaaaggg ctagataagc ttaatatgag tgaaaagcaa attgatcata
    47821 ttaaagcgat tatccagtca atgacgccgg ctgaaagaaa caatccagac acattgaatg
    47881 tatcacgtaa aaagcgtatt gctaaagggt ctggtcgttc attacaagaa gtcaatcgtt
    47941 tgatgaaaca atttaacgat atgaagaaaa tgatgaaaca attcactggt ggcggtaaag
    48001 gtaaaaaagg taaacgcaat caaatgcaaa atatgttaaa aggtatgaat ttaccgtttt
    48061 aatgtttaat ataacacgct gatttttgtt gcaatgagat gtgcatcccg aaagttatac
    48121 taaagaatat aactttatgg ggtgcatatt tttagataca caataataat taaaaactga
    48181 aattgcggat ttgctagaac atgaggttat tgttgctaat attaataagt tatattggtg
    48241 gaacatgtgc gttagaagtg gtaccattca tgtccttacg agataaatta acttaacacg
    48301 taggtggtga aggctactat gaatttttat aacctattaa cagtctaatt tagtaatcac
    48361 atagttatta ttgtaagaaa aaggttcaat aattttcctg gtaaagaaaa aactctttac
    48421 aaacattcat acacctgtta atattatttc ttgtagaaaa taaaaattaa aacatgactt
    48481 aaaggagatt ttataaatgg cagttaaaat tcgtttaaca cgtttaggtt caaaaagaaa
    48541 tccattctat cgtatcgtag tagcagatgc tcgttctcca cgtgacggac gtatcatcga
    48601 acaaatcggt acttataacc caacgagcgc taatgctcca gaaattaaag ttgacgaagc
    48661 gttagcttta aaatggttaa atgatggtgc gaaaccaact gatacagttc acaatatctt
    48721 atcaaaagaa ggtattatga aaaaatttga cgaacaaaag aaagctaagt aatttagcgt
    48781 aaaattgttc taacaataag aataactcgt ttacactgac agttattact caatgatacg
    48841 ttgggaatat cacatgttag taatatagaa cgtattgggt accataatgg tgcccttttt
    48901 ctttgaatta ttttcaatta aaatagaagt gttcaaagca tagagttgga ggtaatagaa
    48961 tgagagttga agttggtcaa attgttaaca cacatggtat taaaggtgaa attaaagtaa
    49021 aatccaattc agactttaca gacgttcgtt ttcaacccgg tcaagtgctg acagttgtgc
    49081 ataacaataa cgaccttgaa tatactgtta agtcacatag agtgcataaa gggcttcata
    49141 tgcttacatt tgaaggtatt aataatatta atgatattga gcatttaaaa gggagttcta
    49201 tttatcaaga gcgtgatcat gaagatatcg tacttgagga aaatgaattt tattattcag
    49261 atattatagg atgtacagtt tttgatgatc aagaaacacc aataggtcgt gtaattaata
    49321 tatttgaaac aggtgcgaat gatgtgtggg tgattaaagg atctaaagaa tatttgattc
    49381 cttatattgc tgatgttgta aaagaagtgg atgttgaaaa taaaaaaatt atcatcacgc
    49441 caatggaagg attgttggat taatgaaaat tgattattta actttatttc ctgaaatgtt
    49501 tgatggtgtt ttaaatcatt caattatgaa acgtgcccaa gaaaacaata aattacaaat
    49561 caatacggtt aattttagag attatgcaat taacaagcac aaccaagtag atgattatcc
    49621 gtatggtggc ggacaaggta tggtgttaaa gcctgaacct gtttttaatg cgatggaaga
    49681 cttagatgtc acagaacaaa cacgcgttat tttaatgtgt ccacaaggcg agccattttc
    49741 acatcagaaa gctgttgaat taagcaaggc tgaccacatc gttttcatat gcggacatta
    49801 tgaaggttac gatgaacgta tccgaacaca tcttgtcaca gatgaaatat caatgggtga
    49861 ctatgtgtta actggcggtg agttaccggc aatgacaatg actgatgcta ttgttagact
    49921 gattccaggt gttttaggta atgaacagtc acatcaagac gattcatttt cagatgggtt
    49981 attagagttt ccgcaatata cacgtccgcg tgaatttaag ggtctaacag ttccagatgt
    50041 tttattgtct ggaaatcatg ccaatattga tgcatggaga catgagcaaa agttgatccg
    50101 cacatataat aaaagacctg acttaattga aaaatatcca ttaactaatg aagataagca
    50161 aatattagaa agatataaaa taggattgaa aaaaggttag tattgtgcta acatattctg
    50221 agtgtggaaa cacaaaaatc actatgatcc gctgctatat atttgtcgag gcaagaacat
    50281 aggttgaaga ggagaattta taatgacaaa tcacaaatta atcgaagcag taactaaatc
    50341 acaattgcgt acagacttac caagtttccg tcctggtgat actttacgtg tacacgtacg
    50401 tatcattgag ggtactcgtg agcgtatcca agtattcgaa ggcattgtaa ttaaacgtcg
    50461 tggcggtggc gtttctgaaa cgtttacagt tcgtaaaatt tcatcaggtg ttggcgtgga
    50521 acgtacattc ccattacaca caccaaaaat tgaaaaaatc gaagttaaac gtcgtggtaa
    50581 agtacgtcgt gctaaattat attacttacg tagtttacgt ggtaaagctg ctagaatcca
    50641 agaaattcgt taatcagcat ttaaacaaag ctatgtatga gtcaaattcg actcaaacaa
    50701 taaagccatc taggtcactt ttatggagtg atatagatgg ctttttttgc tgtttagtta
    50761 atgtaaagtt gataatgtaa ttgttttttc ttatttattc ataacgtgtt tgctcaaaaa
    50821 tgcttatata aacaaaaatc tactaagtgc cattgaaaag gacttagtag atttattaaa
    50881 tatatgcgta gcaacattat ttttgtcttg cccatctcgt gaaaataata ctacatataa
    50941 tgccaaatat agtaattgtt ataagtaaat aatagtatgg tggggtatag ctcaattgaa
    51001 tctttgttat atttttaggt gctttaatgc cggtcataac accatttact tgtgcaactt
    51061 taagactttg atcacctgat gtcgctttca taccttgatt atatgctgtt ggcaaaacaa
    51121 tatacccaga tgaattttta tttttagtaa tagtataacc ttgctttgtc ttactaactt
    51181 tgacagcctc taatgaattt gaagcgtctt taagcgtggt ataatcttcg ccgtatatcc
    51241 cttttaaatt tactcgatac ttacctttag gcaatgataa tctaattcta tctgaagctt
    51301 taatgcgtat cgttacgggt gttacaaagc gtcgatattt ataagtgagt ttatttcttt
    51361 cttgtgtata ttcattcact ttaacatcat gagctttatc cggcgaaagt aattctaaat
    51421 ccatttcaaa atacaaatct ttaaattgat tagaaactga ttttggcaac tgtacagtta
    51481 gaccaccatt attttgttta acttgtaata aatgttttgt aggagattgc caggctgaac
    51541 tatttaattt aattgttgaa tctgatagta aatttttatt ggctttaaaa tgtgtattaa
    51601 catctttagt attgttagaa acaatccctt gcaacattgc ttgttcttta tctaatggag
    51661 attttaattc tttattggaa aagaccttat ttgtaatatg tgcacttgga taatggatgg
    51721 tatttttaga atgaatccaa cgaactttat tgtctttgtg ttcagagtta attttaaatc
    51781 tatatggtaa gttgtcatca tgattcactc taattcgatc attaacattc caaagtgata
    51841 gtaaattttg acgattgcca agtaatctat aagtgctgtt tttatcaatt ggcatattaa
    51901 tttggagtgt cttgtcataa tattttaaaa tgtctccatt aaaaatacta gaatataatg
    51961 aaatgccatt ataatgatat ataaatggtg aatttaatgc atagtctgac atataatcaa
    52021 tgcgattaaa tgggcctgtt gcattttgat ttatcttttt tataagctgg tttacatagt
    52081 tactatggta atcatgttgt ttcaacgttg ataatgattg ttgataaggt ttgattgcca
    52141 tatttttgtt gttatctaaa atgacgattt gttgaatcat aacgattaat actaatattg
    52201 caacggttaa ttttttataa cgccataaac taaattttaa aataacggca agcaccatta
    52261 gcaggataat acctactata agtgcaagtg ggtgtgtcgg tgatagtaat acataaagta
    52321 atgcgatgat acttactggt attgttctga ttaaataata tttcatattt aatgttgata
    52381 aatgttgaat aaacaatccg caaagagcgc ttgatgatag tgctaagata tacacccaac
    52441 gcctttctgg aaatgaaaaa ccattaaaag cactgtcgaa atactgtgat aatgaaccaa
    52501 taaataatat ccatgttact attgcgaaaa gtctataaaa gtaaaaacga tacagtttga
    52561 atgacaataa tgcaacgata gtaagaattg aaatcgtaat ataaaatcca tcgctaaaga
    52621 aaaaataatg ataatcaagt ggtgtcaaaa acggtatatc aacattggga ttttgctttc
    52681 tgtcattttc caaaaacgca gaaatgccag tgaataaacc aaatacactt gataacacac
    52741 tcaaaactgt agcagatatg acgcaaataa atttttgtgt tctagagaca atgtcatatt
    52801 tgtaagtgaa aatgagtcga tataaatagt agcaacctat aataatagct tgataataac
    52861 tgaaataaaa attgctaaat agtgttaagg ctatcgcaac aatgaaaata ccgattttgc
    52921 gttgttgaaa atatctttcc aaaccaagaa tcgataatgg caataaatat aataaatttc
    52981 cataaaatga ccaagtaaaa ttaaagtata taacgacagt tgacatgccg tataaaatcg
    53041 tagcgatcat atttgttgag cgtttaaagt gtaatatttt aaataagtag aaggtcacga
    53101 caaatgttat gatagctcgt atcatagcca taataagttg gtttgtcggc caaaaatgta
    53161 ttgttgtcgg attaaatata ccaaccgttt ctcctatttt aatgaataga aaatttagcc
    53221 acattaaagg tgacagcgaa taataatatg atagtccttt catataatcg ccacctaatc
    53281 caaacgatgc atcatataaa ctagaaaaac tacttagatg ttcatacaaa tacatttgaa
    53341 atggcatcat ttgacggaat ccatctccag ccccactaaa aacagtacca ttcacaatat
    53401 aatcatagat atgagtagaa aataaaataa gcgttaatat tacactaatg aaagttataa
    53461 caaagaattg tttgacgttt gaatttagcc acttttttaa cacaacatta tcctcaactt
    53521 tcaaatttaa aattaagttt aactgaaact aaagttaatg aggttcttga taggtaaaga
    53581 cgaagatgac tgtggaacag ataccttatc atagttactt aaactttgga tcattttcag
    53641 tttatcatta aacaaatata ttgaataata aaaatgtcat actgataaag atgaatgtca
    53701 cttaataagt aacttagatt taacaaatga tgatttttaa ttgtagaaaa cttgaaataa
    53761 tcacttttac ctaaatctaa agcattgtta agaagtgtga caatgttaaa ataaatatag
    53821 ttgaattaat gaatttgttc tataattaac aggttataga ttttaataat gagaaaagaa
    53881 ttgacgaaag taaggtgaat tgaatggtta ttcaatggta tccaggacat atggcgaaag
    53941 ccaaaagaga agtaagtgaa caattaaaaa aagtagatgt agtgtttgaa ctagtagatg
    54001 caagaattcc atatagttca agaaacccta tgatagatga agttattaac caaaaaccac
    54061 gtgttgttat attaaataaa aaagatatgt ctaatttaaa tgagatgtca aaatgggaac
    54121 aattttttat tgataaagga tattatcctg tatcagtgga tgctaagcac ggtaaaaatt
    54181 taaagaaagt ggaagctgca gcaattaagg cgactgctga aaaatttgaa cgcgaaaaag
    54241 cgaaaggact taaacctaga gcgataagag caatgatcgt tggaattcca aatgttggta
    54301 aatccacatt aataaataaa ctggcaaagc gtagtattgc gcagactggt aataaaccag
    54361 gtgtgaccaa acaacaacaa tggattaaag ttagtaatgc attacaacta ttagacacac
    54421 cagggatact ttggcctaaa tttgaagatg aagaagtcgg taagaagttg agtttaactg
    54481 gtgcgataaa agatagtatt gtgcacttag atgaagttgc catctatgga ttaaactttt
    54541 taattcaaaa tgatttagcg cgattaaagt cacattataa tattgaagtt cctgaagatg
    54601 cagaaatcat agcgtggttt gatgcgatag ggaaaaaacg tggcttaatt cgacgtggta
    54661 atgaaattga ttacgaagca gtcattgaac tgattattta tgatattcga aatgctaaaa
    54721 taggaaatta ttgttttgat atttttaaag atatgactga ggaattagca aatgacgcta
    54781 acaattaaag aagttacgca gttgattaat gcggttaata caatagaaga attagaaaat
    54841 catgaatgct ttttagatga gcgaaaaggt gttcaaaatg ccatagctag gcgcagaaaa
    54901 gcgttagaaa aagaacaagc tttaaaagaa aagtatgttg aaatgactta ctttgaaaat
    54961 gaaatattaa aagagcatcc taatgctatt atttgtggga ttgatgaagt tggaagagga
    55021 cctttagcag gtccagtcgt tgcatgcgca acaattttaa attcaaatca caattatttg
    55081 ggccttgatg actcgaaaaa agtacctatt acgaaacgtc tagaattaaa tgaagcacta
    55141 aaaaatgaag ttactgcttt tgcatatggt atcgcgacag ctgaagaaat agatgaattt
    55201 aatatttata aagctactca aatcgccatg cagcgagcta ttgatggatt atcagtacaa
    55261 ccaacgcatt tattgataga cgcgatgacg cttgataatg cactgcctca agtatcttta
    55321 atcaagggtg atgcaagaag tgtgtccatt gcagctgcaa gtatcatggc gaaggttttt
    55381 cgtgatgatt atatgacaca gttatctaaa gattatcctg aatacggttt tgaaaaaaac
    55441 gcgggttatg gtaccaaaca acatttacta gcaatcgatg atattggcat tatgaaagag
    55501 catagaaaaa gctttgaacc tataaaatcg ttactgtaaa tcgtaaaatt caattaaatg
    55561 ataaaaaagt agcatttaag tttacaatag cgcttacatt ttttataatt gtaagggaac
    55621 ttaacctaag taacaggagg atggaagatg aatatccacg agtatcaagg taaagaaata
    55681 tttcgttcaa tgggcgttgc agttccagaa ggacgagtag catttactgc tgaagaagcg
    55741 gtggagaaag caaaagaatt aaattctgat gtatatgttg taaaagcaca aattcatgct
    55801 ggaggtagag gtaaagcagg cggagtaaaa attgctaaat ctttatctga ggtagaaaca
    55861 tatgcaaaag aattattagg gaaaactttg gtgacacatc aaactggtcc agaaggtaaa
    55921 gaaattaaac gtttatatat cgaagaaggt tgtgctattc aaaaagaata ttacgttgga
    55981 ttcgttattg atcgtgcgac tgaccaagta acattgatgg cgtctgaaga agggggcact
    56041 gagattgaag aagttgctgc gaagactcct gaaaagatct tcaaagaaac tatcgatcca
    56101 gtaatcggac tttcaccatt ccaagcaaga cgaattgcgt ttaatattaa tattcctaaa
    56161 gaatctgtta acaaagctgc taaattctta ttagcacttt ataatgtatt cattgaaaaa
    56221 gattgttcaa tcgtagaaat caacccatta gttacaacag ctgatggtga tgtattggca
    56281 ttagatgcta aaattaattt tgatgataat gcattattca gacataaaga tgttgtagaa
    56341 ttacgtgatt tagaagaaga agatccgaaa gagattgaag cgtctaaaca tgatttatca
    56401 tacattgcat tagatggtga catcggatgt atggttaatg gtgcaggttt agccatggca
    56461 acaatggata cgattaatca tttcggtgga aacccagcca atttcttaga tgcaggcgga
    56521 agcgctacta gagaaaaagt aactgaagca tttaaaatca ttttaggtga tgaaaatgtt
    56581 aaaggtattt ttgtaaacat tttcggtggc attatgaaat gtgatgttat cgcagaaggt
    56641 atcgttgaag ctgtaaaaga agtagattta actttaccac tagttgtacg cttagaaggt
    56701 acaaatgttg agttaggtaa aaaaatctta aaagactcag gattagcaat tgaaccagca
    56761 gcaacaatgg ctgaaggtgc acaaaaaatt gttaaactag tcaaagaagc ataaggaaag
    56821 gatgggagca ctaagatgag tgtatttata gataagaata ctaaagtaat ggtacaaggt
    56881 attacagggt ctactgccct tttccataca aaacaaatgc ttgattatgg tacgaaaata
    56941 gtagcaggtg tgacgcctgg taaaggtggt caagttgttg aaggcgttcc tgttttcaac
    57001 actgttgaag aagctaaaaa tgaaactggg gcaacggttt cagtcattta cgttccagca
    57061 ccatttgctg cagactcaat tttagaagca gctgatgcag acttagatat ggttatttgt
    57121 atcactgaac atattcctgt attagacatg gttaaagtta aacgctactt acaaggtaga
    57181 aaaacacgtt tagttggtcc gaactgtcca ggtgtgatta cagcagatga atgtaaaatt
    57241 ggtattatgc ctggctatat tcacaaaaaa ggtcatgttg gtgtagtatc acgttcaggt
    57301 acactaacat atgaagcagt gcaccaattg actgaagaag gtattggtca aactacagct
    57361 gttggtattg gtggagaccc agtcaacgga acaaacttta ttgatgtttt aaaagcattc
    57421 aatgaagatg acgaaacgaa agcagttgtt atgattggtg aaatcggtgg tacagctgaa
    57481 gaagaagcag ctgaatggat taaagcgaat atgacaaaac cagttgtagg ctttatcggt
    57541 ggacaaacag cacctcctgg aaaacgtatg ggacatgctg gtgcaatcat ttcaggtggt
    57601 aaaggtactg ctgaagagaa aataaaaaca ttaaatagtt gtggtgtgaa aacagcggca
    57661 acaccttcag aaattggttc aacattaatt gaagctgcta aagaagcagg tatttatgaa
    57721 tcattattaa cagttaataa ataaagttaa aagatgatat aaatggctat agcccattcc
    57781 atactttata aaagtatcgg aaatgggcta tttgtcgtgc aatgaatttt agtacacttt
    57841 tcatattttg gaaagacaag ttaattattt tacctcctac aatagcttta taaaacaaag
    57901 aaaattttaa ttaaaatata tagtgcacta cgttataatg tttatatatt attgtaagga
    57961 gtgttccatc atgaataaac aacaaagtaa agtacgctat tcaattagaa aagttagtat
    58021 tggaattttg tcaatttcaa taggtatgtt tttggcattg ggtatgtcga acaaagcata
    58081 tgcagatgaa attgataaat ctaaagattt tacaagaggg tatgagcaaa atgtattcgc
    58141 gaaatcagag ttaaatgcta ataaaaatac gacaaaagac aaaataaaaa atgaaggtgc
    58201 tgttaaaaca tcggacacaa gtttaaagtt agacaacaaa tcagcaattt caaacggaaa
    58261 tgaaattaat caagatataa agatttcaaa tactccgaaa aactcaagcc aaggtaacaa
    58321 tctagttatt aataacaatg aacctactaa agaaattaaa attgcaaact tggaagctca
    58381 aaattctaat cagaagaaaa cgaataaagt tactaataat tactttggtt actacagttt
    58441 tagagaagct ccaaaaacac aaatctatac tgtaaaaaaa ggagacacac ttagtgctat
    58501 agcattaaaa tacaaaacta cagtttcaaa tattcaaaat acaaataata tagcaaatcc
    58561 taatttaata tttattggtc aaaaattaaa agtgccaatg acaccattag tagaaccaaa
    58621 accaaaaaca gtgtcttcaa ataataaaag taatagtaat agcagtacat taaattattt
    58681 gaaaacatta gagaatagag gatgggattt cgacggtagt tatggatggc aatgtttcga
    58741 tttagttaat gtatattgga atcatcttta tggtcatgga ttaaaaggat atggagctaa
    58801 agatatacca tatgcaaata attttaatag tgaagctaaa atttatcaca acacaccaac
    58861 tttcaaagct gaacctgggg acttagtggt ttttagtgga agatttggtg gaggatatgg
    58921 tcatacagct attgtcttaa atggtgatta tgatggaaaa ttaatgaagt tccaaagttt
    58981 agatcaaaac tggaataatg gtggatggcg taaagcagag gttgcacata aagttgttca
    59041 taattatgaa aatgatatga tttttattag accatttaaa aaagcataat ttaaatcgaa
    59101 ggcaggacat tgaaatatga aattttcaac tttaagtgaa gaagaattta ccaactacac
    59161 caaaaagcac ttcaaacatt atacacagtc tatagaatta tataattata gaaataaaat
    59221 aaatcatgaa gcacatattg tgggagtgaa gaatgataaa aatgaagtta tagctgcatg
    59281 tttattaaca gaggcacgaa tttttaaatt ctacaaatat ttctactctc atagaggtcc
    59341 tttacttgat tatttcgatg ctaaattagt ttgttacttt tttaaagaat tatctaaatt
    59401 catttataaa aatagaggag tatttattct tgttgatcca tatttaatag agaatttaag
    59461 agatgcaaat ggtaggataa taaagaatta taataattca gtgatagtaa agatgctagg
    59521 gaaaattggg tatctccatc aaggttatac aacaggatat tcaaataaaa gtcaaattag
    59581 gtggatttct gtattggatt taaaagataa agatgagaat caacttttaa aagaaatgga
    59641 ataccaaact agaagaaata taaaaaagac tattgagatt ggtgttaagg ttgaagattt
    59701 atctattgaa gaaacaaatc gattttataa attgtttcaa atggctgaag aaaaacatgg
    59761 ttttcatttc atgaatgaag attattttaa acgaatgcaa gaaatatata aagataaggc
    59821 aatgttaaag atagcttgta taaatcttaa tgaatatcaa gataaattaa aaatacaatt
    59881 attgaaaatc gaaaat
//
LOCUS       DAPDIM010000008        55253 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000008 DAPDIM010000000
VERSION     DAPDIM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 55253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55253
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.008"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            428..2473
                     /locus_tag="RFE25_000539"
     CDS             428..2473
                     /locus_tag="RFE25_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIABC"
                     /protein_id="HDU2815639.1"
                     /translation="MRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAIQGEALQHY
                     LPFIQNGGVQNVAKLMTAAGSIIFENLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMN
                     KTMGDFLQVTPKNVTDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPS
                     YLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGF
                     IKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQG
                     EFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPL
                     LFFIHAVLDGLSFLTLYLLDVHLGYTFSGGFIDYVLLGVLPNKTQWWLVIPVGLVYAV
                     IYYFVFRFLIVKLKYKTPGREDKQSQAVTASATELPYAVLEAMGGKANIKHLDACITR
                     LRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENP
                     TTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIK
                     PSQGEVRAPFNGKIQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQ
                     EVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK"
     gene            complement(2452..2553)
                     /locus_tag="RFE25_000540"
     CDS             complement(2452..2553)
                     /locus_tag="RFE25_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815640.1"
                     /translation="MMPQNTIAKKKQARHLMKVYAPVYSKHYLASNN"
     gene            2746..4386
                     /locus_tag="RFE25_000541"
     CDS             2746..4386
                     /locus_tag="RFE25_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-keto acid decarboxylase family protein"
                     /protein_id="HDU2815641.1"
                     /translation="MKQRIGAYLIDAFHRAGVDKIFGVPGDFNLAFLDDIISNPNVDW
                     VGNTNELNASYAADGYARLNGLAALVTTFGVGELSAVNGIAGSYAERIPVIAITGAPT
                     RAVEQAGKYVHHSLGEGTFDDYRKMFAHITVAQGYITPENATTEIPRLINTAIAERRP
                     VHLHLPIDVAISEIEIPTPFEVTATKDTDASTYIELLATKLHQAKQPIIITGHEINSF
                     HLHQELEDFVNQTQIPVAQLSLGKGAFNEENPYYMGIYDGKIAEDKIRDYVDNSDLIL
                     NIGAKLTDSATAGFSYQFNIDDVVMLNHHNIKIDDVTNDEISLPSLLKQLSNISYTNS
                     ATFPAYHRPTSPDYTVGTEPLTQQTYFKMMQNFLKPNDVIIADQGTSFFGAYDLALYK
                     NNTFIGQPLWGSIGYTLPATLGSQLADKDRRNLLLIGDGSLQLTVQAISTMIRQHIKP
                     VLFVINNDGYTVERLIHGMYEPYNEIHMWDYKALPAVFGGKNVEIHDVESSKDLQDTF
                     NAINGHPDVMHFVEVKMSVEDAPKKLIDIAKAFSQQNK"
     gene            4453..5010
                     /locus_tag="RFE25_000542"
     CDS             4453..5010
                     /locus_tag="RFE25_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family protein"
                     /protein_id="HDU2815642.1"
                     /translation="MINFNKTALVLIDLQEGILKMDYAPHTAENVVQNANKLIDVFRK
                     NNGFIAFVRVNFYDGKDVLQPNAMISLPPKEGDDYSRFHHLLDKRDDDFVIDKRHFSA
                     FVGTDLDLQLRRRGIDTIVLGGVATHIGVDTTARDAYQLNYNQFFVTDMMSAQNETLH
                     QFPIDNVFPLMGQTITTNDFLNILN"
     gene            5289..6638
                     /gene="brnQ"
                     /locus_tag="RFE25_000543"
     CDS             5289..6638
                     /gene="brnQ"
                     /locus_tag="RFE25_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDU2815643.1"
                     /translation="MKKKLTFKENMFIGSMLFGLFFGAGNLIFPIHLGQAAGSNVFIA
                     NLGFLITAIGLPFLGIIAIGISKTSGLFEIASRVNKTYAYIFTIALYLVIGPFFALPR
                     LATTSFEIAFSPFLSPKQITLYLFIFSFVFFVIAWFFARKPSRILEYIGKFLNPVFLV
                     LLAIILLFAFIHPLGGISDAPISKQYQSHALFNGFLDGYNTLDALASLAFGIIIVATI
                     KKLGIENPTDIAKETIKSGTISIIMMGIIYTLLAIMGTLSIGHFKLSENGGIALAQIT
                     QYYLGNYGIVLLSLIVMVACLKTAIGLITAFSETFEHLFPKMNYLAIATVVSFISFLF
                     ANVGLTKIIMYSVPVLMFLYPLAIALIVLTLFSSKFHHSKIIYQCTIFFTMIAALVDG
                     LKASPEFISSTSFSQTLINFSQKYLPLSDIGMGWVVLSLIGFIIGFIIYKIKHRKIP"
     gene            6897..8081
                     /gene="rocD"
                     /locus_tag="RFE25_000544"
     CDS             6897..8081
                     /gene="rocD"
                     /locus_tag="RFE25_000544"
                     /EC_number="2.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="HDU2815644.1"
                     /translation="MNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCIS
                     GFSVANQGHCHPTIVKAMTEQASKLSIISRVLYSDNLGKWEEKICHLAKKDKVLSLNS
                     GTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHP
                     LLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQI
                     LMIADEIQVGLGRTGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTP
                     GTHGSTFGGNPLAIAISTAALDVLKDEQLVERSERLGSFLLKALLQLKHPSIKEIRGR
                     GLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVF
                     KN"
     gene            8120..9151
                     /locus_tag="RFE25_000545"
     CDS             8120..9151
                     /locus_tag="RFE25_000545"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDU2815645.1"
                     /translation="MIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKL
                     TFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSKTCIPPLVEKGIHVIDLSGAFRIK
                     NREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLI
                     SEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSI
                     IAGQDVSVIFTPHLVPMTRGILSTIYVKFSSEYTTESLHKLMTSYYANQPFVRIRDIG
                     TFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQAIQNLNILYDFEVTT
                     GLNQSPVYP"
     gene            9163..10404
                     /gene="argJ"
                     /locus_tag="RFE25_000546"
     CDS             9163..10404
                     /gene="argJ"
                     /locus_tag="RFE25_000546"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDU2815646.1"
                     /translation="MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFG
                     WIYSSSLASSAAVYTLNQFKAAPLIVTEDTLQKSKGKLQALVVNSANANSCTGQQGID
                     DARQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKTGTEHIKDTNFATPGAFNEA
                     ILTTDTCTKHIAVSLKIDGKTVTIGGSAKGSGMIHPNMATMLAFITTDASIESNTLHQ
                     LLKSSTDHTFNMITVDGDTSTNDMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTF
                     LAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKSAIFGEDANFGRIIT
                     AIGYSGCEIDPKCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHEHVTIDVQLGLGNAA
                     ATAYGCDLSYDYVRINASYRT"
     gene            10420..11184
                     /gene="argB"
                     /locus_tag="RFE25_000547"
     CDS             10420..11184
                     /gene="argB"
                     /locus_tag="RFE25_000547"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDU2815647.1"
                     /translation="MKFIVIKIGGSTLSDMHPSIINNIKHLRSNNIYPIIVHGGGPFI
                     NEALSNQQIEPHFVNGLRVTDKATMTITKHTLIADVNTALVAQFNQHQCSAIGLCGLD
                     AQLFEITSFDQQYGYVGVPTALNKDALQYLCTKFVPIINSIGFNNHDGEFYNINADTL
                     AYFIASSLKAPIYVLSNIAGVLINDVVIPQLPLVDIHQYIEHGDIYGGMIPKVLDAKN
                     AIENGCPKVIIASGNKPNIIESIYNNDFVGTTILNS"
     gene            11454..11933
                     /locus_tag="RFE25_000548"
     CDS             11454..11933
                     /locus_tag="RFE25_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HDU2815648.1"
                     /translation="MGIFIYAGIIGGLLSGIVKLGWEVMFPPRTPERNATNPPQELLQ
                     QLGFSSEFTHQTYTFSNMELPWVSFIVHFSFSIVIAIIYCILVKKYAYLAIGQGAVFG
                     IAIWVLFHLIIMPIMHTVPAVWDQPYQEHLSEFFGHIVWMMTIELVRQHFVYRYKLN"
     gene            complement(12261..12905)
                     /locus_tag="RFE25_000549"
     CDS             complement(12261..12905)
                     /locus_tag="RFE25_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HDU2815649.1"
                     /translation="MTVFVMQLQSNLKSIEELISQSRWSYKKPRTVNYRYNQDKLMHR
                     LGDILVQYGIQHDTGLLPHEWHYHISPRGKADIVQHNRDGQPIYVSLSYSYPYIVCVV
                     DKEPVGIDIEKISQRLDWRTLVTCFSTNEAHQICSLNDFYQIWTQKESFTKLIGEGLI
                     KGLDIYDMTQSHFYQSREVKFKQFIFDQFMVQVCFLGEAPWGYKKVSVFQLLSS"
     gene            complement(12918..20093)
                     /locus_tag="RFE25_000550"
     CDS             complement(12918..20093)
                     /locus_tag="RFE25_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDU2815650.1"
                     /translation="MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMY
                     ALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELS
                     TYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTR
                     QHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDD
                     MTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQ
                     RFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLA
                     DIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTE
                     RDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDL
                     AHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKD
                     ATPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNP
                     KGTLIPHRGIVRLVHRNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKK
                     EQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVD
                     LLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCG
                     VGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLY
                     RKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNK
                     IKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHL
                     LCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFE
                     LAQAIAKVQEQNYEVIPEAIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSG
                     LNVAQLQQAVQHLIARHEILRTQYIVVDDEVRQRIVADVVADFEEVNTHFTDEQEIMR
                     QFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLL
                     PLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFT
                     MNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQM
                     LGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRN
                     PLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYTINIEYNTD
                     LYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGN
                     KSIISYFNEVVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFT
                     ERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVI
                     QLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLL
                     NLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPEQLQ
                     QLINKHRVTVASIPLQMCSIMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPS
                     ESTVITSYWSHHCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAI
                     GYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELD
                     EIENVILAIRGISDCVVTVSHFDTHDILNAYYVGEQQVEQDLKQYLNDQLPKYMIPKT
                     ITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVG
                     VDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMYQNQQSLVALP
                     DNLSELQKIVMSRYNLGILEDSLSHRPLGNTLLTGATGFLGAYLIEALQGYSHRIYCF
                     IRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHA
                     GARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSE
                     ADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTN
                     RFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMP
                     VKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMN
                     HISEKWPTITNNWLYHWAQYIKTIFNK"
     gene            complement(20540..21790)
                     /locus_tag="RFE25_000551"
     CDS             complement(20540..21790)
                     /locus_tag="RFE25_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2815651.1"
                     /translation="MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGI
                     YLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFC
                     VAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGY
                     SMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLV
                     LKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMIN
                     TVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGE
                     IIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMF
                     IVLTIGASMLVAGVFGGQKQVNTN"
     gene            complement(22176..23201)
                     /locus_tag="RFE25_000552"
     CDS             complement(22176..23201)
                     /locus_tag="RFE25_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent formate dehydrogenase"
                     /protein_id="HDU2815652.1"
                     /translation="MKIVALFPEAVEGQENQLLNTKKAIGLKTFLEERGHEFIILADN
                     GEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNI
                     GVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIG
                     IFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSSSDAITIHAPLT
                     PETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAP
                     ADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIA
                     SKSYTAK"
     gene            complement(23375..23734)
                     /locus_tag="RFE25_000553"
     CDS             complement(23375..23734)
                     /locus_tag="RFE25_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2294 domain-containing protein"
                     /protein_id="HDU2815653.1"
                     /translation="MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAH
                     MTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDID
                     LNDDEVISIFVFDKSIE"
     gene            complement(23951..24982)
                     /locus_tag="RFE25_000554"
     CDS             complement(23951..24982)
                     /locus_tag="RFE25_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA/acyl-ACP dehydrogenase"
                     /protein_id="HDU2815654.1"
                     /translation="MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALR
                     KNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLS
                     NPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFIL
                     RANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQ
                     IPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTS
                     HLSELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHL
                     GKLEAELKG"
     gene            complement(24995..25756)
                     /locus_tag="RFE25_000555"
     CDS             complement(24995..25756)
                     /locus_tag="RFE25_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815655.1"
                     /translation="MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVG
                     KSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNTIEPLFQLI
                     RPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLN
                     LTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLN
                     LEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE"
     gene            complement(25753..26724)
                     /locus_tag="RFE25_000556"
     CDS             complement(25753..26724)
                     /locus_tag="RFE25_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDU2815656.1"
                     /translation="MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPI
                     THSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQ
                     KGSNIKAVALGHHEGNVIMGQKGMHLNEFNNGDDYHFGIPHRYSTHYLLLEELRKQLK
                     IKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAY
                     CCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAA
                     WTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS"
     gene            complement(26738..27478)
                     /locus_tag="RFE25_000557"
     CDS             complement(26738..27478)
                     /locus_tag="RFE25_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815657.1"
                     /translation="MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLL
                     NVIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDE
                     EINAQLKLVDLEDRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY
                     KLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRN
                     DSHLLKIRNEIMETFALNHHQVEPEYYL"
     gene            complement(27820..28332)
                     /locus_tag="RFE25_000558"
     CDS             complement(27820..28332)
                     /locus_tag="RFE25_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4242 domain-containing protein"
                     /protein_id="HDU2815658.1"
                     /translation="MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENL
                     THGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIP
                     EGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAV
                     DTPIDGIEKL"
     gene            28511..28714
                     /locus_tag="RFE25_000559"
     CDS             28511..28714
                     /locus_tag="RFE25_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815659.1"
                     /translation="MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILK
                     PKDVVLDVDSIKEIDENHLNDAT"
     gene            complement(29009..29968)
                     /locus_tag="RFE25_000560"
     CDS             complement(29009..29968)
                     /locus_tag="RFE25_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDU2815660.1"
                     /translation="MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVI
                     EFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILVAF
                     LNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQED
                     NINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRN
                     AWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEG
                     DDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT"
     gene            complement(30615..32102)
                     /locus_tag="RFE25_000561"
     CDS             complement(30615..32102)
                     /locus_tag="RFE25_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDU2815661.1"
                     /translation="MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHI
                     TRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGK
                     PIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNF
                     PMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESG
                     NAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVE
                     GIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTG
                     KDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEI
                     FGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQ
                     VPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY"
     gene            32529..32912
                     /locus_tag="RFE25_000562"
     CDS             32529..32912
                     /locus_tag="RFE25_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HDU2815662.1"
                     /translation="MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDR
                     FYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRVGLII
                     MVIIQTAVLFTFVKTLPKSNHKIEE"
     gene            32919..33245
                     /gene="isdI"
                     /locus_tag="RFE25_000563"
     CDS             32919..33245
                     /gene="isdI"
                     /locus_tag="RFE25_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylobilin-forming heme oxygenase IsdI"
                     /protein_id="HDU2815663.1"
                     /translation="MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLN
                     TEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDI
                     GYHYQK"
     gene            complement(33310..34455)
                     /gene="cap8P"
                     /locus_tag="RFE25_000564"
     CDS             complement(33310..34455)
                     /gene="cap8P"
                     /locus_tag="RFE25_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8P"
                     /protein_id="HDU2815664.1"
                     /translation="MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDML
                     DSVLSIFDIQADHDLNIMQDQQTLADLTANALAKLDSIINEEQPDMILVHGDTTTTFV
                     GSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFE
                     NKDKERIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIF
                     KAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSY
                     LVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIED
                     DEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRSDKPDEFVPLRHK"
     gene            complement(34532..35794)
                     /gene="cap8O"
                     /locus_tag="RFE25_000565"
     CDS             complement(34532..35794)
                     /gene="cap8O"
                     /locus_tag="RFE25_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8O"
                     /protein_id="HDU2815665.1"
                     /translation="MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQI
                     SIEEPGLQEVYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALD
                     SILPFLEKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDICLVHCPERVLPGKILE
                     ELVHNNRIIGGVTKACIEAGKYVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALA
                     NELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKL
                     IQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLN
                     QEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVI
                     FDTKNVVKSSFEDVSYYNYGNIFNFIDK"
     gene            complement(35848..36735)
                     /gene="capN"
                     /locus_tag="RFE25_000566"
     CDS             complement(35848..36735)
                     /gene="capN"
                     /locus_tag="RFE25_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide type 5/8 biosynthesis
                     epimerase CapN"
                     /protein_id="HDU2815666.1"
                     /translation="MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSF
                     KDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYG
                     KEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCP
                     GNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTS
                     SVMYEIRRQSHRKTVLINMPSVLNKYFNKLSVFRKLFGNLTYSNTLYENNNALEVIPG
                     KMSLVIADIMDETTTKDKA"
     gene            complement(36735..37292)
                     /gene="cap8M"
                     /locus_tag="RFE25_000567"
     CDS             complement(36735..37292)
                     /gene="cap8M"
                     /locus_tag="RFE25_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8M"
                     /protein_id="HDU2815667.1"
                     /translation="MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPT
                     INNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEM
                     SIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTH
                     QSMMLDMYIIYKTIKNIVTSEGVHH"
     gene            complement(37303..38508)
                     /gene="cap8L"
                     /locus_tag="RFE25_000568"
     CDS             complement(37303..38508)
                     /gene="cap8L"
                     /locus_tag="RFE25_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8L"
                     /protein_id="HDU2815668.1"
                     /translation="MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGW
                     PYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKY
                     DQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYI
                     NRHVYKNAENVIVLGTEMKNYLLNHRISKNADNIHVIPNWYDMRQLQDNRIYNDTFKA
                     YREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDH
                     RIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKPLVLIMD
                     KQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREIN
                     TMKYYNLLK"
     gene            complement(38509..39714)
                     /locus_tag="RFE25_000569"
     CDS             complement(38509..39714)
                     /locus_tag="RFE25_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HDU2815669.1"
                     /translation="MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSI
                     LTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVSILLISILIESIALIIVFL
                     YFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLFLYY
                     LIQNWIVCFITSELFATIYTLVKLRGLTIGEYQSEDNNVVKDYVMLLSTNSLNNLNLY
                     LDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSYISVNESDNIKKQYLKT
                     NLFAIAALCLVMIICYPITLIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLN
                     TKHASITLQANYMTLHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKS
                     KFINKKDVD"
     gene            complement(39707..40873)
                     /locus_tag="RFE25_000570"
     CDS             complement(39707..40873)
                     /locus_tag="RFE25_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDU2815670.1"
                     /translation="MKFFVLCAIISMNIFIVISTFTKEVLGFPIEPVYYSTMVGIALI
                     TTVFAIYKIIVTQEIPRGLILLIAICLLYLAFYYFSPDKEEKLAKNNILFFLTWAVPA
                     AISGIYIKYINKATVERFFKLVFFIFSISFIFVILIPKLTGEIPSYINFGLMNYQNAS
                     YLSAFTAGLGIYFIMKGSVKHKWIYVLFTIIDIPIVFIPGGRGGAILLILYGLFAFIL
                     ITFKRGIPIAVKSIMYIFALSISSVLIYFLFTKGSNTRTFSYLQGGTLNLEGTSGRGP
                     IYEKGIYFIQQSPLLGYGPFNYYKLIGNIPHNIIIELILSFGLLGFFIIMICILLLVY
                     KMIRNYDPNTIDLLVMFIAIYPITLLMFSSNYLVVSEFWFVLFYFITKGRRHHG"
     gene            complement(40887..41996)
                     /locus_tag="RFE25_000571"
     CDS             complement(40887..41996)
                     /locus_tag="RFE25_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDU2815671.1"
                     /translation="MRILNIVSSNIVQDPRVLKQIETIKGVTNDYKIVGMNNSQATNR
                     RLENLDCNYRLLGSKVDPKNILSKLIKRIRFATGVIREIKAFKPDVIHANDFDVLLMV
                     YLSNYKKANIVYDAHEIYAKNAFINKVPLISKFVESIEKHIVKHRVNAFVTVSHAAKE
                     YYQSKGYKKEANVITNAPILNDSREFKEIENFKEIVYQGQIVMDRGYEEFIIASSAFK
                     QNAPSFIIRGFGPHEEVIKELISYNSENIRLDKPVEVKELVDKLAESNVGVILTKPVS
                     INFEYTVSNKIFECIHAGLPVILSPVKEHIYLNEKYKFGIVLKEVTPLEIEKAVRKLR
                     DNHDLFNHLRQNAIKASKILNWQIESERLVELYKF"
     gene            complement(42001..42627)
                     /locus_tag="RFE25_000572"
     CDS             complement(42001..42627)
                     /locus_tag="RFE25_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic acetyltransferase"
                     /protein_id="HDU2815672.1"
                     /translation="MRIAIEKIIGLLKNQSSKESNVKIHRLAYITNSKFDGNNYIDRW
                     CKIRNSHIGEYSYIGFGSDFNNVEVGRYCSISSDVKIGLGKHPTHFFSSSPIFYSNNN
                     PFNIKQKFIDFNDQPSRTTIKNDVWIGANVIIMDGLTINTGAVIAAGSVVTKNVGAYE
                     VVGGVPAKVIKKRFDNKTIEKLLESKWWEKTPDKLKGFSVEYLNKKDT"
     gene            complement(42630..43754)
                     /gene="cap8G"
                     /locus_tag="RFE25_000573"
     CDS             complement(42630..43754)
                     /gene="cap8G"
                     /locus_tag="RFE25_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8G"
                     /protein_id="HDU2815673.1"
                     /translation="MEKLKLMTIVGTRPEIIRLSSTIKACDQYFNQILVHTGQNYDYT
                     LNQIFFDDLELRQPDHYLEAVGSNLGETMGNIIAKTYDVLLREQPDALLILGDTNSCL
                     AAVSAKRLKIPVFHMEAGNRCFDQNVPEEINRKIVDHVSDVNLPYTEHSRRYLLDEGF
                     NKANIFVTGSPMTEVIEAHRDKINHSDVLNKLGLEPQQYILVSAHREENIDNEKNFKS
                     LMNAINDIAKKYKMPVIYSTHPRSWKKIEESKFEFDPLVKQLKPFGFFDYNALQKDAF
                     VVLSDSGTLSEESSILKFPGVLIRTSTERPEVLDKGTVIVGGITYNNLIQSVELAREM
                     QNNNEPMIDAIDYKDTNVSTKVVKIIQSYKDIINRNTWRK"
     gene            complement(43758..44867)
                     /gene="cap8F"
                     /locus_tag="RFE25_000574"
     CDS             complement(43758..44867)
                     /gene="cap8F"
                     /locus_tag="RFE25_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8F"
                     /protein_id="HDU2815674.1"
                     /translation="MNIVITGAKGFVGKNLKADLTSTTDHHIFEVHRQTKEEELESAL
                     LKADFIVHLAGVNRPEHDKEFSLGNVSYLDHVLDILTRNTKKPAILLSSSIQATQDNP
                     YGESKLQGEQLLREYAEEYGNTVYIYRWPNLFGKWCKPNYNSVIATFCYKIARNEEIQ
                     VNDRNVELTLNYVDDIVAEIKRAIEGTPTIENGVPTVPNVFKVTLGEIVDLLYKFKQS
                     RLDRTLPKLDNLFEKDLYSTYLSYLPSTDFSYPLLMNVDDRGSFTEFIKTPDRGQVSV
                     NISKPGITKGNHWHHTKNEKFLVVSGKGVIRFRHVNDDEIIEYYVSGDKLEVVDIPVG
                     YTHNIENLGDTDMVTIMWVNEMFDPNQPDTYFLEV"
     gene            complement(44880..45908)
                     /gene="cap8E"
                     /locus_tag="RFE25_000575"
     CDS             complement(44880..45908)
                     /gene="cap8E"
                     /locus_tag="RFE25_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8E"
                     /protein_id="HDU2815675.1"
                     /translation="MFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDD
                     IRKKYNNSKLKFYIGDVRDSQSVETAMRDVDYVFHAAALKQVPSCEFFPVEAVKTNII
                     GTENVLQSAIHQNVKKVICLSTDKAAYPINAMGISKAMMEKVFVAKSRNIRSEQTLIC
                     GTRYGNVMASRGSVIPLFIDKIKAGEPLTITDPDMTRFLMSLEDAVELVVHAFKHAET
                     GDIMVQKAPSSTVGDLATALLELFEADNAIEIIGTRHGEKKAETLLTREEYAQCEDMG
                     DYFRVPADSRDLNYSNYVETGNEKITQSYEYNSDNTHILTVEEIKEKLLTLEYVRNEL
                     NDYKASMR"
     gene            complement(45898..47721)
                     /gene="cap8D"
                     /locus_tag="RFE25_000576"
     CDS             complement(45898..47721)
                     /gene="cap8D"
                     /locus_tag="RFE25_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8D"
                     /protein_id="HDU2815676.1"
                     /translation="MAHLSVKLRLLILALIDSLIVTFSVFVSYYILEPYFKTYSVKLL
                     ILAAISLFISHHISAFIFNMYHRAWEYASVSELILIVKAVTTSIVITMVVVTIVTGNR
                     PFFRLYLITWMMHLILIGGSRLFWRIYRKYLGGKSFNKKPTLVVGAGQAGSMLIRQML
                     KSDEMKLEPVLAVDDDEHKRNITITEGVKVQGKIADIPELVRKYKIKKIIIAIPTIGQ
                     ERLKEINNICHMDGVELLKMPNIEDVMSGELEVNQLKKVEVEDLLGRDPVELDMDMIS
                     NELTNKTILVTGAGGSIGSEICRQVCNFYPERIILLGHGENSIYLINRELRNRFGKNV
                     DIVPIIADVQNRARMFEIMETYKPYAVYHAAAHKHVPLMEDNPEEAVHNNILGTKNTA
                     EAAKNAEVKKFVMISTDKAVNPPNVMGASKRIAEMIIQSLNDETHRTNFVAVRFGNVL
                     GSRGSVIPLFKSQIEEGGPVTVTHPEMTRYFMTIPEASRLVLQAGALAEGGEVFVLDM
                     GEPVKIVDLARNLIKLSGKKEDDIRITYTGIRPGEKMFEELMNKDEVHPEQVFEKIYR
                     GKVQHMKCNEVEAIIQDIVNDFSKEKIINYANGKKGDNYVR"
     gene            complement(47741..48505)
                     /gene="cap8C"
                     /locus_tag="RFE25_000577"
     CDS             complement(47741..48505)
                     /gene="cap8C"
                     /locus_tag="RFE25_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8C"
                     /protein_id="HDU2815677.1"
                     /translation="MIDIHNHILPNIDDGPTNETEMMDLLKQATTQSVTEIIVTSHHL
                     HPRYTTPIEKVKSCLNHIESLEEVQALNLKFYYGQEIRITDQILNDIDRKVITGINDS
                     RYLLIEFPSNEVPHYTDQLFFELQSKGFVPIIAHPERNKAISQNLDILYDLINKGALS
                     QVTTASLAGISGKKIRKLAIQMIENNLTHFIGSDAHNTEIRPFLMKDLFNDKKLRDYY
                     EDMNGFISNAKLVVDDKKIPKRMPQQDYKQKRWFGL"
     gene            complement(48508..49194)
                     /gene="cap8B"
                     /locus_tag="RFE25_000578"
     CDS             complement(48508..49194)
                     /gene="cap8B"
                     /locus_tag="RFE25_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8B"
                     /protein_id="HDU2815678.1"
                     /translation="MSKKENTTTTLFVYEKPKSTISEKFRGIRSNIMFSKANGEVKRL
                     LVTSEKPGAGKSTVVSNVAITYAQAGYKTLVIDGDMRKPTQNYIFNEQNNNGLSSLII
                     GRTTMSEAITSTEIENLDLLTAGPVPPNPSELIGSERFKELVDLFNKRYDIIIVDTPP
                     VNTVTDAQLYARAIKDSLLVIDSEKNDKNEVKKAKALMEKAGSNILGVILNKTKVDKS
                     SSYYHYYGDE"
     gene            complement(49210..49878)
                     /gene="capA"
                     /locus_tag="RFE25_000579"
     CDS             complement(49210..49878)
                     /gene="capA"
                     /locus_tag="RFE25_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide type 5/8 biosynthesis
                     protein CapA"
                     /protein_id="HDU2815679.1"
                     /translation="MESTLELTKIKEVLQKNLKILIILPLLFLIISAIVTFFVLSPKY
                     QANTQILVNQTKGDNPQFMAQEVQSNIQLVNTYKEIVKSPRILDEVSKDLNDKYSPSK
                     LSSMLTITNQENTQLINIQVKSGHKQDSEKIANSFAKVTSKQIPKIMSVDNVSILSKA
                     DGTAVKVAPKTVVNLIGAFFLGLVVALIYIFFKVIFDKRIKDEEDVEKELGLPVLGSI
                     QKFN"
     gene            complement(50221..52830)
                     /gene="adhE"
                     /locus_tag="RFE25_000580"
                     /gene_synonym="adhC"
     CDS             complement(50221..52830)
                     /gene="adhE"
                     /locus_tag="RFE25_000580"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDU2815680.1"
                     /translation="MLTIPEKENRGSKEQEVAIMIDALADKGKKALEALSKKSQEEID
                     HIVHQMSLAAVDQHMVLAKLAHEETGRGIYEDKAIKNLYASEYIWNSIKDNKTVGIIG
                     EDKEKGLTYVAEPIGVICGVTPTTNPTSTTIFKAMIAIKTGNPIIFAFHPSAQESSKR
                     AAEVVLEAAMKAGAPKDIIQWIEVPSIEATKQLMNHKGIALVLATGGSGMVKSAYSTG
                     KPALGVGPGNVPSYIEKTAHIKRAVNDIIGSKTFDNGMICASEQVVVIDKEIYKDVTN
                     EFKAHQAYFVKKDELQRLENAIMNEQKTGIKPDIVGKSAVEIAELAGIPVPENTKLII
                     AEISGVGSDYPLSREKLSPVLALVKAQSTKQAFQICEDTLHFGGLGHTAVIHTEDETL
                     QKDFGLRMKACRVLVNTPSAVGGIGDMYNELIPSLTLGCGSYGRNSISHNVSATDLLN
                     IKTIAKRRNNTQIFKVPAQIYFEENAIMSLTTMDKIEKVMIVCDPGMVEFGYTKTVEN
                     VLRQRTEQPQIKIFSEVEPNPSTNTVYKGLEMMVDFQPDTIIALGGGSAMDAAKAMWM
                     FFEHPETSFFGAKQKFLDIGKRTYKIGMPENATFICIPTTSGTGSEVTPFAVITDSET
                     NVKYPLADFALTPDVAIIDPQFVMSVPKSVTADTGMDVLTHAMESYVSVMASDYTRGL
                     SLQAIKLTFEYLKSSVEKGDKVSREKMHNASTLAGMAFANAFLGIAHSIAHKIGGEYG
                     IPHGRANAILLPHIIRYNAKDPQKHALFPKYEFFRADTDYADIAKFLGLKGNTTEALV
                     ESLAKAVYELGQSVGIEMNLKSQGVSEEELNESIDRMAELAFEDQCTTANPKEALISE
                     IKDIIQTSYDYKQ"
     gene            complement(53215..54390)
                     /locus_tag="RFE25_000581"
     CDS             complement(53215..54390)
                     /locus_tag="RFE25_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDU2815681.1"
                     /translation="MFIGKNLEYVRKLNALSRKELSEKINVSEQAIWQYETKNMMPEI
                     SKIYDMTSIFNVKSSYFISEQPEELLINSVDKHSIAFRAKNYKVSTKLLNKQYYQAMY
                     LSNLTSYLFSFVTIPDNIILSLINNLDELLNGNLESLNKKESIKEIAKVVRAKILQDE
                     SNEALLFMLEKAGIVIYEKRINDSIDAYSFWSKDQTPFIILGTNRGVAVRRNFDLAHE
                     LGHLVLHRHIQFDLLSPEEYKTIEHEADIFASEFLLPEEAFKKDFDQMTKKSNPDYLA
                     VLKEKWYVSIQAIAMRAYYLGLMSSTQYRYFWASLNKKGYKSKEPLDDVIEMSRPVKM
                     NSLLKLYFDRNILTPQKLLNYLKVDETFLNHLAGINLKLFKDYVNENREYNITNLYK"
     gene            complement(54396..55163)
                     /locus_tag="RFE25_000582"
     CDS             complement(54396..55163)
                     /locus_tag="RFE25_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016170495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815682.1"
                     /translation="METIKQEVRESIVKGIIAGYKDYVNERNEVKKRMVISDAYAFTK
                     SNHIESQVAKHLENFVKYIKENAGPSWKYLKFIFNKDEEKNNIMFILKNEDYFDEKNV
                     SVGKSLVADKNPKSKNYLEVLMAKNRDINFGTVGEDFEIGHQMTADSILFNIKEGSNR
                     DINSYFLIITYRIDKESKQLAAIKQWLPNPETNSAIMVDDLTELIEKVIVEREDYHID
                     EEELEVLKNDGELELIDVEHAFGISIDEGNDMIESER"
BASE COUNT        17613 a        10343 c         8226 g        19071 t
ORIGIN      
        1 ccatcaaaga ttatcctttc ttttaagtgc tgataatagc tgctactgct ggattattac
       61 aacaactttt atacatttta ttcaggatta tcttatatta tgttttaata ataatctgtg
      121 aacatttaag agatttgaaa ttgaatttaa taattgtatt gaaaacgcat acttcaccat
      181 gctaaaatag gagtcgcaaa caaataagat tcaataagat gtgatggtaa gctagataaa
      241 ctaacgtatc agttttatat actacttagt caattgcttc ttttacatta attacataca
      301 ccaacgtgtt actaagtaag attaggcatg agttaaatta agctgtgatg gttaccaaca
      361 cagtctattt gctcgtgtct tttttattga atcttaaata ttacatacaa ctttggaggt
      421 tggacaagtg aggaagaaac ttttcggtca attgcaacgt attggtaaag cgctaatgtt
      481 acctgttgca attttaccag cagcgggtct gttattagct atcggtacag ctatacaagg
      541 cgaagcatta caacactact tgccgtttat acaaaatggt ggcgttcaaa atgtcgctaa
      601 attaatgaca gctgccggta gtattatttt tgaaaactta cctatgattt tcgcattagg
      661 tgtcgcaatc ggattagctg gcggtgatgg cgtagcagct atcgcagcat tcgtcggtta
      721 cataatcatg aacaaaacaa tgggcgactt tttacaagtt acacctaaaa atgttactga
      781 tccagcgagt ggttacgcta gcattttagg tattccaaca ttacaaacag gtgtgttcgg
      841 cggtattatt atcggggccc tggcagcttg gtgttataac aagttctata acattaactt
      901 accatcttat ttaggtttct tcgctggtaa gcgtttcgta cctattatga tggctacaac
      961 atcatttatt ttagcatttc caatggcatt aatttggcca acgattcaat caggattaaa
     1021 tgcattcagt acaggattat tagattcaaa tactggtgtt gccgtattct tatttggttt
     1081 catcaagcgt ttattaattc cattcggtct acatcacatt ttccacgcac cgttctggtt
     1141 cgagtttggt tcatggaaaa atgcagctgg tgaaattatt cacggtgacc aacgtatctt
     1201 tatcgaacaa attcgtgaag gcgcacattt gacagctggt aaattcatgc aaggtgaatt
     1261 ccctgttatg atgttcggtt tacctgcagc agctttagca atttatcaca cagctaaacc
     1321 tgaaaataag aaagtagtag caggtttaat gggttctgct gctttaacat cattcttaac
     1381 tggtattaca gaacctttag aattctcatt cttattcgta gcaccattat tattctttat
     1441 tcacgcagta cttgatggtt tatcattctt aacattgtac ttattggatg ttcacttagg
     1501 ttatactttc tcaggtggtt tcatcgacta cgttttactt ggcgtactac ctaataagac
     1561 acaatggtgg ttagtcattc ctgtaggtct tgtatacgca gttatttact acttcgtatt
     1621 ccgattctta attgtaaaat taaaatacaa aacaccaggt cgtgaagata agcaatcaca
     1681 agctgttact gcttcagcaa ctgaattacc atatgcagta ttagaagcta tgggtggcaa
     1741 agcaaacatt aaacatttag acgcttgtat cacacgtcta cgtgttgaag ttaacgacaa
     1801 atctaaagtt gatgttcctg gtttgaaaga tttaggcgca tctggtgtat tagaagtcgg
     1861 caataatatg caagcaattt ttggtcctaa atctgaccaa atcaaacatg aaatgcaaca
     1921 gattatgaat ggtcaagtag tagaaaaccc tactactatg gaagacgata aagacgaaac
     1981 tgttgttgtt gcagaagata aatctgcaac aagcgaattg agccatatcg ttcatgcacc
     2041 attaactggt gaagtaacac ctttatcaga agtgcctgat caagtgttca gcgaaaaaat
     2101 gatgggtgac ggtatcgcta ttaaaccttc acaaggtgaa gttcgtgcac cattcaacgg
     2161 taaaatacaa atgattttcc caacaaaaca tgcaattggt cttgtatcag atagtggttt
     2221 agaactatta atccacatcg gtttagacac tgttaaatta aacggagaag gctttacttt
     2281 acatgttgag gaaggtcaag aagttaaaca aggtgattta ttaatcaact ttgatttaga
     2341 ctacatccgc aatcatgcaa agagtgatat tacgcctatt atcgtgacac aaggaaacat
     2401 tacaaacctt gattttaaac aaggtgaaca tggcaacatt tcatttggcg atcaattatt
     2461 tgaagctaaa taatgcttac tataaacagg tgcgtatacc ttcataaggt gacgcgcctg
     2521 ttttttcttt gctattgtat tttgcggcat cattgatagt tcgctctccc cttaaatttt
     2581 gaatattaag atcatcaatt taagcccccc ttcatactca tttcctaaaa agtattaatt
     2641 gttcactatt gttagcgttt tcacaacaaa gtcaacttcc ttgaccttac actgtattcg
     2701 aggctatcat tttaagtgta aatatagaga aaaggtggtt tttttatgaa acaacgcatt
     2761 ggagcttact taattgacgc ttttcatcga gcaggcgtcg ataaaatttt tggtgttcct
     2821 ggtgatttta atctcgcttt tctagacgat attatcagca atcccaatgt agattgggta
     2881 ggaaatacaa atgaattaaa cgcaagttac gcagcggacg gttatgcccg tcttaatgga
     2941 ctcgctgcat tagttactac atttggtgtt ggcgaattaa gtgccgtcaa cggtatcgca
     3001 ggttcatatg ctgaacgcat acctgtcatt gcgattacag gtgcgccgac acgtgctgtt
     3061 gaacaagccg gtaaatatgt acatcactca cttggtgaag gtacatttga cgactaccga
     3121 aaaatgtttg cacatataac cgttgcacaa ggttatatca cacctgaaaa tgcaacaacc
     3181 gaaataccac gtttaattaa tacagcaatc gccgaaagac gcccagttca tttacattta
     3241 ccaatcgatg tcgcaatctc tgaaattgag ataccgacac catttgaagt gacggcaact
     3301 aaagatacgg atgcatcaac atatatagag ttattagcaa ctaaactgca tcaagcgaag
     3361 cagcctatca tcattactgg acatgaaatt aacagttttc acctccatca agaattagaa
     3421 gattttgtaa atcaaacaca gataccagta gcacaacttt cattaggaaa aggtgctttt
     3481 aatgaggaaa atccatatta tatgggtatt tacgacggga aaattgccga agataaaata
     3541 cgagattatg tggacaacag cgatttaatt ttaaatattg gagccaaatt aacagattca
     3601 gcaacagcag gattttcata ccaattcaat atcgatgatg tcgttatgtt aaatcatcac
     3661 aatatcaaaa ttgatgatgt tacaaatgat gaaatatctc taccatcgtt gttaaaacag
     3721 ttatccaata tttcatatac gaacagtgca acgttccctg cgtatcatcg tccaacatca
     3781 cccgattata ctgttggcac agaaccatta acacaacaaa cttattttaa aatgatgcaa
     3841 aatttcttaa aaccaaatga tgtcattatt gctgatcaag gtacatcatt ctttggtgct
     3901 tatgatttag cattatacaa aaacaatact tttatagggc aaccgttatg gggttctatc
     3961 ggctatacat tacctgcaac attaggttca caattagcag acaaagatcg tcgtaactta
     4021 ttattaattg gtgatggctc attgcaacta actgttcaag ctatttcaac tatgattaga
     4081 cagcatatta aaccggtatt atttgtgatt aataatgacg gctatacggt agaacgactt
     4141 attcacggca tgtatgaacc ttataatgaa attcacatgt gggattataa agctttacca
     4201 gctgtatttg gtggtaaaaa tgttgaaatt catgacgttg aatcatcaaa agatttacaa
     4261 gacacgttta atgcaattaa tggtcatccc gatgtgatgc attttgtcga agtcaaaatg
     4321 tctgtcgaag acgcaccgaa gaaactgatc gatatcgcta aagctttttc acaacaaaat
     4381 aaataatttc atcgtataca gggtataagt ttaagcgaat actttattaa acgaaaagga
     4441 ctctgatata agatgattaa ttttaataaa accgctttag tgttaatcga cctgcaagaa
     4501 ggtatactta agatggatta tgcgccacat acagctgaaa atgtcgttca aaacgctaat
     4561 aaattaatag atgtttttag aaaaaacaat ggctttatcg cttttgttcg cgtgaatttc
     4621 tatgatggta aagatgtatt gcaaccaaat gcaatgatct cattaccacc aaaagaaggc
     4681 gacgactaca gtcgtttcca tcatttatta gacaagagag atgacgattt tgtcatagac
     4741 aaacgacatt ttagtgcatt tgtaggaaca gatttggact tacaattgcg acgtcgagga
     4801 attgatacga ttgttcttgg tggtgtcgca acgcatattg gcgtagatac gacagcgcga
     4861 gatgcctatc aattaaacta caatcagttt tttgttacag atatgatgag tgcacaaaac
     4921 gaaacgctac atcaatttcc aatagataat gtattcccat taatgggaca aacaataact
     4981 acaaacgact ttctaaatat attgaactaa acatacactt acccccttcg atcatgttga
     5041 agggggtatc tttattttac aaagtattaa tacgtcgggt tgtctaacct cctatctata
     5101 aacttagcct atatctatta aatcgttctt aacttacgcc cctactacat aaaaaacagt
     5161 atttattccg gaattttcaa aaaatttagt atttattaca aaattatgta tcactttagg
     5221 tttaattttt gatattatct taattaagta gatttttata agttctaaaa aggagaacaa
     5281 atacatatat gaagaagaaa ctaacattta aagaaaacat gtttataggt tctatgttat
     5341 ttggtttatt ctttggtgcc ggcaatctta tcttcccaat acacttgggt caagctgctg
     5401 gttctaacgt ttttatcgct aacttaggat ttttaattac agcaattggc ttaccatttc
     5461 taggtatcat tgctattggc atttcaaaga catctggttt atttgaaatt gcatcgcgtg
     5521 ttaataaaac atatgcttac attttcacga ttgccttata tctagttatc ggaccatttt
     5581 tcgccttacc tagactggca acgacatcat ttgaaattgc attttcgcca tttttatcac
     5641 caaagcaaat cactttatat ttatttattt ttagcttcgt cttctttgtg attgcatggt
     5701 tttttgcgag aaagccatca agaattttag aatatatcgg taaattttta aatccggtat
     5761 tcttagtatt attagcaatt attttattat ttgcttttat ccatccatta ggtggcatat
     5821 ctgatgcacc tattagtaaa caatatcaat cacatgcctt atttaacggc tttttagatg
     5881 gatacaatac cttagatgcg ctagcgtcat tggcatttgg tatcatcatt gttgcaacga
     5941 ttaaaaagtt aggtatcgaa aatccaactg atatcgctaa agaaacaatt aagtctggta
     6001 ctatcagtat cattatgatg gggattattt ataccctact agcaatcatg ggtacattaa
     6061 gtattggtca tttcaaactt agtgaaaatg gtggtattgc cttagcgcaa attacgcaat
     6121 actacttagg taactacggt atcgtcctgt tgtcacttat cgttatggtt gcttgtttaa
     6181 aaacagccat cggtttgatt acggcatttt ctgaaacatt cgaacacctt ttccctaaaa
     6241 tgaattacct agcgattgca acagttgtaa gctttatttc gttcttattc gcgaatgttg
     6301 gcttaactaa gattattatg tactcagtcc cagtgttaat gttcttatat ccattagcaa
     6361 ttgccttgat tgtactaaca ttatttagta gcaaattcca tcattcaaaa attatttatc
     6421 aatgtaccat tttctttaca atgattgctg cattagtaga tggattaaaa gctagtccag
     6481 agttcatttc aagcacatca ttctcacaaa ctttgattaa tttcagccaa aaatatttac
     6541 cattatcaga cattggtatg ggctgggttg ttctcagttt gattggtttc attatcggct
     6601 tcattattta taaaattaag catcgtaaaa ttccataagc ataatactat gccacagtca
     6661 tatgttaaac atatgcttgt ggcatttttt attcatacta cattaaactg caatcgtata
     6721 catacatatc actgattatc cacaaaaaat attagtactt tcattttaca aatcacatta
     6781 atacaaacac aaccttatct ttatattatt aaatttacat ttgacactta tattgaacaa
     6841 ctgtaatata ttaatattaa ttctttaaat tgtataaata taaaggaggg agaccgatga
     6901 attcaatcat tgaattaact gattattata gctctaataa ttatgcacca cttaagcttg
     6961 tcatttctaa aggtaaaggt gtcaaagttt gggatactga tggcaaacaa tatatagatt
     7021 gcatttcggg tttttcagtt gcaaaccaag gccattgtca tccaacaatt gttaaagcga
     7081 tgacagaaca agcttcaaag ttgtctatca tttcacgtgt cctttatagt gacaatctcg
     7141 ggaaatggga agaaaaaatt tgtcatcttg ctaagaaaga caaagtactc tcccttaact
     7201 ctggtactga agctgttgaa gcagccatta aaattgctag aaaatggggc tctgaagtta
     7261 aaggcattac tgacggacaa gttgaaatca tcgctatgaa taacaatttt cacggtcgta
     7321 cacttggctc attatcacta tctaaccacg acgcatataa agcaggattt caccccctac
     7381 ttcaaggcac tacaactgta gattttggag acattgaaca attaacacaa gctatttcac
     7441 cgaatacagc agcaattatt ttggaaccaa ttcaaggtga aggtggcgtt aatataccac
     7501 cgaaaggata tattcaagct gtgcgtcaac tatgtgataa acatcaaata ttaatgattg
     7561 cagatgaaat tcaagttggt cttggtagaa ctgggaaatg gtttgcgatg gaatgggaac
     7621 aagttgttcc agacatttat attttaggta aggcattggg tggcggctta taccctgtat
     7681 ctgctgtact tgcaaataat gatgtcatgc gtgttctaac accaggtaca catggttcaa
     7741 catttggtgg taacccttta gccattgcaa tatcgacggc agcgcttgat gtacttaaag
     7801 atgaacaact ggttgaacga tcagaacgct taggttcatt tttattaaaa gcgttgctac
     7861 aacttaaaca tcctagtatt aaagaaatta gaggtcgtgg tttatttata ggcatagagc
     7921 ttaacacaga tgctgcacct tttgtggatc aactgattca acgtggaatc ttatgcaaag
     7981 acacgcatcg tactatcatt cgattgtctc cacctctagt tattgataaa gaggaaatcc
     8041 atcaaattgt tgcagctttt caagacgttt ttaaaaatta acaattaatc atttatatat
     8101 gacataggag ggattcatga tgattaaagt aggtatcgtt ggcggtagcg gttatggcgc
     8161 aattgaatta attcgattgt tacaaacaca tcctcatgta acgattgcac acatctactc
     8221 acattcaaaa gtagatgaac cgttgaaatt aacatttcca catttacaac atattatgca
     8281 acatttcgaa gcacttacag tggacaataa tgactgtgat gtaattttct ttgcgacacc
     8341 agcacccgta agtaaaacat gtatccctcc cttagtagaa aaaggtattc atgttatcga
     8401 tttatctggc gcatttagaa ttaagaatcg tgaaatatat gaagcatatt acaaagaaac
     8461 tgctgcagca caagatgatt tgaatcatgc tatttacagc atttcagaat ggcaatcgtt
     8521 tgataacaat ggaacgaagc tcatttctaa tcctggctgt ttccctacag caacattatt
     8581 agcattacat ccacttatta gcgaaaaaat agtagatttg tcatctatta ttattgatgc
     8641 taagaccggc gtgtcaggtg ctggtcgttc attatcacaa cgtgttcatt tttcagaaat
     8701 gaatgaaaat ctaagtgctt atgcaatcgg aaaccataaa cacaaaccgg aaatcgagca
     8761 atatttatct atcattgcgg gtcaagatgt atcagtcata tttacaccac atctcgtacc
     8821 aatgacacga ggtattttat caacaattta tgtcaaattt tcatctgaat atacgactga
     8881 atcattacat aaattaatga cctcttatta tgctaatcag ccatttgtca gaattagaga
     8941 tattgggact tttccaacca caaaagaagt actcggtagt aactactgcg atatcggtat
     9001 ctatgtagat gaaacaacac aaacagcaat tttagtatca gtgattgata accttgtcaa
     9061 aggcgcaagt ggtcaagcca ttcaaaattt aaatatatta tatgattttg aagtaacgac
     9121 tggcctaaat caatcaccag tttatccata aggggtgtta gaatgaaaca tcaagaaacg
     9181 acatcacaac aatataactt ttcaattatt aaacatggcg atatcagtac acctcaaggc
     9241 ttcacggctg gtggtatgca catcggttta cgcgctaaca aaaaagactt tgggtggatt
     9301 tactcatcgt ctttggcaag ttcagctgcc gtatatactt taaatcagtt taaagctgca
     9361 ccacttattg tcactgaaga cactttacaa aagtctaaag gaaaattaca agcacttgtt
     9421 gttaattcag ctaatgcaaa ttcttgtacc ggtcaacaag gcatagatga tgcacgacaa
     9481 acacaaacat gggttgctca acaacttcaa ataccatctg agcatgttgc tgttgcttca
     9541 actggggtca ttggtgaata tttgcctatg gataaaatta agactgggac cgaacatatt
     9601 aaggatacta attttgcaac gccaggtgcg tttaacgagg caattttaac aactgatacc
     9661 tgtacaaaac atatcgctgt atcactaaaa atcgatggta aaaccgttac aattggtggt
     9721 agcgccaaag gttcaggtat gattcatcca aatatggcta ccatgcttgc ttttataaca
     9781 accgatgcat cgattgaatc gaatacactt catcaattat taaaatcttc gactgaccat
     9841 acatttaata tgattactgt tgatggcgat acaagtacaa atgacatggt attagtcatg
     9901 gcaaatcacc aagttgaaca ccaaatactt agtcaagacc atccacaatg ggaaacattt
     9961 gttgatgcat tcaattttgt ctgtacattt ttagctaaag ctatagccag agatggcgaa
    10021 ggcgcaacaa agttaatcag cgtcaatgtg tcaggcgcta aatcaatatc agatgcaaga
    10081 aaaatcggta aaactatcgt aagttcaaat ctagtaaaat cagctatttt tggcgaagat
    10141 gccaattttg gtcgaatcat tacagctatt ggctatagcg gatgtgaaat tgatcctaaa
    10201 tgcacatatg ttcaactgaa ccaaatacct gtcgtggata aaggtatggc tgtactattt
    10261 gatgagcaag ctatgtcgaa cacattaact catgaacatg tcacaattga cgttcaactt
    10321 ggtttaggta acgctgcagc gactgcatac ggttgtgatt tatcctatga ttatgtgcgt
    10381 attaacgcat catatcgaac ataaggtggt gttggttaga tgaaatttat tgtcattaaa
    10441 attggtggca gtacacttag tgacatgcat ccatcaatta ttaacaacat taagcattta
    10501 cgatcaaaca acatctaccc cattatcgtt catggcggtg gcccatttat taatgaagca
    10561 ttatcaaacc agcaaatcga gccacacttt gttaatggcc taagagtgac tgataaagca
    10621 accatgacca ttactaaaca cacgctcatt gcagacgtta acactgcatt agtagctcaa
    10681 tttaaccagc accaatgttc tgcaataggc ttatgtggtt tggatgcaca gctgtttgaa
    10741 attacatctt ttgatcaaca atatggatat gtcggtgttc cgaccgcttt aaataaggat
    10801 gctttacagt atttatgtac taaatttgta cctatcatca attcgattgg tttcaataac
    10861 catgatggag aattttacaa tattaatgct gacacgcttg cctattttat tgcatcatca
    10921 ttaaaagcgc ctatttatgt attaagtaat attgcaggtg tactcatcaa tgatgttgtt
    10981 atacctcaat tgccattagt cgatattcat caatatattg aacatggtga tatttatgga
    11041 ggtatgattc ccaaagtgct agatgccaaa aatgcgattg aaaatggctg tcctaaagtt
    11101 atcattgcat caggaaacaa gccaaatatc attgaatcta tttacaataa tgattttgtt
    11161 ggcacaacaa tccttaattc ataactatga aattaaggcc taacaagttt tgacacgcga
    11221 gatgattcca gttcgattat ccattgcgct aaaacattta tttaccgttc atctcgttaa
    11281 caattttgaa tacagtacga tacaatatga gatgtaaaaa actaataacc ttttacaaat
    11341 ttgtttatca aaatatttta agttttgcaa agctttttat tgtgattatt ttcacaaaat
    11401 actataatga ggatagtaaa tagagaggag tccttaagtt gacgaaacga caaatgggta
    11461 tattcattta tgctggaatt atcggtggct tgttatctgg aattgtaaaa ttaggttggg
    11521 aggtcatgtt tccacctcgc acaccagaac gtaatgcaac gaacccacct caagagttat
    11581 tgcaacaatt aggatttagt agtgagttta cgcatcaaac atatacattt tcaaatatgg
    11641 aattgccttg ggtaagcttt attgtccact ttagtttttc tatcgtcatt gcaattattt
    11701 actgcatatt agttaaaaaa tacgcttact tagcaattgg acaaggtgct gtttttggta
    11761 ttgctatttg ggtattattc caccttatca ttatgccaat catgcatact gtacctgctg
    11821 tgtgggatca accataccaa gagcatctgt cagaattctt tggccatatc gtctggatga
    11881 tgacaattga attagtgcga caacattttg tctatcgcta taaattaaat taatacactg
    11941 actaacatta acgtgagttt taaatcatcg tttgagtatg atgattgatg ctcacgttat
    12001 tttattaact gacatgatat gattccagcc aacttacgtg agcattaaag tctcaaatgc
    12061 gtcgtaacaa gatattattt ttggcaattt caatattgct cagtatattt tcaccttatc
    12121 acttacatta atctcgtcat gattttgaat gatgccatcg tgtattcacc tttcattttt
    12181 ccaataaaaa tacatctaac agtaaacatt taggcagtat agtttaaaat cactgcgcaa
    12241 tgatactgtc agacgtcata ttaactactc aataactgaa atacagacac ttttttataa
    12301 ccccagggtg cctctcctaa gaaacatacc tgtaccataa actgatcaaa aataaattgt
    12361 ttgaacttca cttcacgtga ttgataaaag tgtgattgtg tcatatcata aatgtccaat
    12421 cctttgatta aaccttcacc aatcaatttt gtaaaacttt ctttttgtgt ccatatttga
    12481 taaaaatcat ttaaactaca tatttgatgt gcttcgtttg tagagaaaca cgtcactaac
    12541 gtacgccagt ctaaacgttg tgatatcttt tcgatatcta taccaactgg ttctttatcg
    12601 acaacacaca cgatataagg ataactatat gataagctca catagatggg ctgtccatca
    12661 cgattgtgtt gaacaatatc tgccttacct cgtggcgaaa tgtgataatg ccattcatgt
    12721 ggtaataaac ctgtgtcatg ttgaattcca tattgcacta aaatatctcc caatctgtgc
    12781 atgagtttat cttgattgta tctatagttg actgtacgcg gttttttata tgaccaacga
    12841 ctttgtgata ttaattcttc aatacttttc aagttactct gtaattgcat tacaaatact
    12901 gtcataactt tccctactta cttattgaat attgttttga tatattgtgc ccaatgatac
    12961 agccaattgt tagttatcgt tggccatttt tcactgatgt gattcattat ttttaatgtt
    13021 aatgttgtat ctatcattgc tagttgttgt tcacggtcaa cactagttaa tccaatcgtt
    13081 tcgtacatgt cttgtttctg taaaatttca ttaaatgatt catcgctgac gagttcaatt
    13141 tctttgcgct taacgcattc taacaaagat ttcaccggca ttttattagg tgatagcaca
    13201 tggtaaatga tttgtggtgt gttgacctgt gctaatgcga caatttgtct tgcagtcgta
    13261 tccacaaaag aaaaatctac aggcatttca gccatgctaa ccccgataca atccagttgt
    13321 aacaaatcat tcattaccat tgaaaaacgg ttagtcttta tatttctcat atgccatctt
    13381 ccattgtaag gactcgtcaa attaccaaca cgtacaatcc gaccatctaa gccattattt
    13441 acagcttcta atacttttaa ttcactataa aatttgctcc gtgtatatgg tgatgttagt
    13501 agttgccctt tatagacatc cgcttctgaa aatgtcacat cttctgtgtc tatatcaaaa
    13561 taagttccca cacttatcgt agacacatat attaaccttg catgatgttg ttgtgccaaa
    13621 cgtatgacat caacagtacc ttgaacattt actttttcaa attcatcatc atcaccaaag
    13681 tgatccgtac gagcacctgc atgaataatc gtatccatgt tttcaggtaa aacaacatca
    13741 tccatacact cgaaatcacc aacaatgact tcaatgtttg ataacatcat ttcaaccgtc
    13801 tcttctgaaa aataatcatt taaattcgtc atcaacttat accatgctat ttcctcatta
    13861 tcagcacgta tgaaacaata aatgcgatga ctgtatcctt gtagtgcttc aatcagataa
    13921 gcacctaaaa aacctgtcgc gccagtcaat agtgtatttc ctagaggtcg atgacttaga
    13981 ctatcctcta aaatacccaa gttataacga gacataacaa tcttttgtaa ttccgaaaga
    14041 ttatccggta atgcaactaa tgattgttga ttttggtaca tataattaac aatctgtcgc
    14101 acggttttat attggtataa tgtctgcatt gaaatatgat ggccaaatcg ttttaaatgc
    14161 gagacaacta acatcgcctc taatgagtta ccaccaagtt caaagaaatc atcgtcaaca
    14221 ccgacatcat tttgtttcaa tacctctcca aatacatcaa caaatgtctg ctcaatttca
    14281 ttagagggtt cgctatacac tttattagac tgttgtatag gtgatggatt tggcaaacgc
    14341 gtagtatcca ccttgtcatt cgtggttaat ggcatacaat cgatatgcgt tatagtctta
    14401 ggaatcatat acttaggcag ctgatcattt aaatattgct tcaaatcctg ctccacttgt
    14461 tgctctccga cataataagc attcaatata tcatgcgtat caaagtgact tactgttaca
    14521 acacaatcag atataccacg aatagctaat attacatttt caatttcatc aagttcaata
    14581 cggtacccgt taactttcac ttgtttatct attcttccta aaaattcaat ttgaccatca
    14641 gatgtataac gtgctaaatc accactatga tacaactttc ctttaccaaa tggattattt
    14701 tgccatttat cagccattaa ttctggacgg ttaatatatc ctatcgctaa actatcacct
    14761 gcaatacaca actcgcctgg cataccaata ccgcataaca aaccatctga cataatatac
    14821 acttggatgt tagataaggg tttgccaatt ggaatcgtct caggtatcaa atcaccacaa
    14881 tgatgtgacc aatacgatgt gatgactgtt gactcagatg gtccataggc attgaaatac
    14941 gtgccacaat gcttctcaat atatttaaca aaggatgccg tactagttgc cccgcctgta
    15001 atcaactttt caatataaaa gtcttccata atactacaca tctgtaacgg aatcgacgca
    15061 accgtcacac gatgcttatt aatgagttgt tgtaactgtt ctggattaac acgttcctct
    15121 ctatctggaa tcacaagcgt atgaccattt aacaaacaac aataaatctc cataactgat
    15181 gcatcaaaaa caatatttgc atgttgcaaa aatacttcat tgtcgcctaa ttgcaattca
    15241 gttgaccatg catgcactaa attcaacaaa tttcgttgtc gtatggcaac ccctttaggc
    15301 atcccggtcg taccagatgt gtaaatagca tacatctcat tatctaacat cgctgtgttt
    15361 tcaagttgat tgccatgtaa atcatcatat tgttcatttt cctttgattc aacaaagcct
    15421 ttagcatttt ccaattgaat gactggtaat gtcgtttcaa tttcaacgcc gtaagacatg
    15481 actgcagtta ctttagcatc ctccaaaatt gcaccttgtc gtttattcgg aaaatcaata
    15541 tcgataggta tataagatgc acctacttta actgtcgcca acatcgccgc aatcatttca
    15601 aaactacgtt ctgtaaacaa ggcaacccgt tgaccattgc ccacaccatt tgataggagc
    15661 atgtgcgcaa tggcatccac atagttgcgt aatgtttcat acgtcattgt caaatcattc
    15721 atgactagcg caacatgatt accttgtcgt gagacaactt cattaaagta acttatgata
    15781 gatttatttc ccgggacatt aagcattcga tcgttaacat gcgtattgac ccaatttaga
    15841 agttcctccg taccgtttgg tatatcacaa atttgtagtg tatcttgatg cttcaaaata
    15901 taatcaatca taatcataca ttgattaccc atgtgacgaa ctgtttctga gtgatataaa
    15961 tcggtattat actcgatatt gattgtatag tcatcgcgat cttcttcaat gatgaaagat
    16021 aaatcaaatt tcgccgtcac tgatttgggt tgaatgtgtg ttaatttact atgcccaaaa
    16081 tgagcatgat tcgtttcatt gttttgtagt actaacatga catcaaataa tggattccgt
    16141 gaggcatcat gtgattgatc taagtcattt actaaacatt cgaatgggta ttcttgatgc
    16201 tcgtatgcct ccaaactcat ttccttaacc tcttgtaaaa actgtgtcca cattttatca
    16261 ggtgacggtt gccctctata taccaacgta ttagcaaaca tgcctagcat ttgctccgtg
    16321 cctttatgca tacgcgcact catcacacta ccgacaacaa catcatcttt tcgagcatat
    16381 ctgcttaaca acgtcatgac cacactcata aagaacataa aatcagtaat ttgatgcttt
    16441 tctacatact tttgaagtag ctgtctcatt tgttgattca ttgtaaatga catcattgct
    16501 ccatttgtcg ttttaatatt tggtctaaca tagtctgtcg gtaagcttaa aataggtact
    16561 tcatctttga attgagataa ccaatattgt ctatgtttcg tcatatcacg atgcgacatc
    16621 cactcactat agtctttata ttgcaattta agtggtaaca ataatttatg ttgataaagt
    16681 gcgttaagat cattcattaa ttgtatatta ctcataccgt cattaatgat atgatgtgta
    16741 tctataaaca ggtatgcatg taagggactt ctaatgtatc tcactctaat ttgacttggc
    16801 ttttccaaat taaaaggtgc cacaaattgg cgcataattt cttgttcatc cgtaaaatgc
    16861 gtgttaactt cttcaaagtc agctacaaca tctgccacaa tacgttgtcg aacctcatca
    16921 tctacaacaa tatattgtgt tcgtagaatc tcatgtcgcg ctatcaaatg ctgaactgct
    16981 tgttgcaatt gagctacatt aagtcctgat gataaccgcc ataaaaaagg tacgttatac
    17041 accgtatctt tatggtttga tttccataat aaatacatac gcttttgtgc agagctcagc
    17101 acataatcat ctttaactat agcttctgga atcacttcat agttttgttc ttgaacctta
    17161 gcaatcgctt gtgctagttc aaatacagtt ggcttttgta ataaatcacc aatttgtaat
    17221 cgtttcccag tagatgcctc tatccgattc accactaacg ttgcttttaa tgaatggcca
    17281 cctaattcaa agaaattatc atgaatacct acttgattca catgtaaaat atctgcaaaa
    17341 atttggcata gcaagtgttc ggtatctgta ctcggtgcta cataggcatc cgtatcgaca
    17401 tagtccatga taggcaatgc cttcttatct aatttcccat taatagtaat aggaatttgc
    17461 tcaatatgca tgaaattaac tggtatcatg tactccggta aggtcatacg taattgtgat
    17521 ttaatcttat tatgtgataa tgtatgcatc gcttcataat aagcaacgat atactgatct
    17581 tgatcatgat tttgaacaat aacaactgct ttattaatac cttgtatacg ctcgagcgca
    17641 tgctcaacct ctgacaactc aatcctaaac cctcgaatct taacttgttt gtcctttcga
    17701 tataaataat ctatgttgcc atcgggtaac aaacgaacga tatcaccact tctatacatc
    17761 agctgattta tatttgaatc tttgataaat ttatctgctg tcaattctgg ctgatttaaa
    17821 taacctgcag ctaacccaaa gccacttgta cataattctc caggaatacc aacgccacac
    17881 cgacgctcgc cttgcatgat ataaacatga gtacccagaa tcggtttacc aataggaata
    17941 cgatttggaa ctttgttagg tatattatac gtcgttgtaa atgttgtatt ttcagttggt
    18001 ccataaccat taataatttg aggatgcttc ggtttttgat taagcaaatc cacccactta
    18061 gcattcaata cttctccacc aattaataaa tactttaacg gtaccaatac ttctattcgt
    18121 tcactagcaa tctgattaaa taatgaggag gttaaccaca tagtattaac gtcattttca
    18181 ttgattaatt gttctaccgc tattggattt aataattgtt cttttttagc aacaatcagc
    18241 tttccaccat tgagcaatgc accatatatt tcaaatgttg cagcatcaaa ggctatagtt
    18301 cctgataaca aaattgtcgt ctcttcattt aatggtacat aatgatttcg atggaccaag
    18361 cgaacaatac ctcggtgcgg aattagtgtc cctttagggt taccagttgt ccccgacgtg
    18421 taaataacat aagcatgatc ttctaacgtg ttacatttag aaagattatc aatatttttc
    18481 cacgctatct tattcaaatc aatgtgatta atattttgtt taccattttc atataaagct
    18541 tggtacgtta ttacaacttt aggcgttgca tcttttaaaa tgtactcctg acgatcactt
    18601 ggatagttcg gatcaattgg cacgtaagcc ccaccagctt tcaacacacc tatcatcgct
    18661 attatcatct caatactttt ttcagctatg acagcgacac gatcattagg ttcaacacca
    18721 tactggtttc tcaaacggtg tgctaaatca ttcgcgcgtg cattcaatgt ttgatatgtt
    18781 ataaacactc cgtcaaattg cacagcgaca tgattcggcg ttgcttcaac ttgttgctca
    18841 aataaggtaa caactgtttg cgcatcatct atctcaggca aacttaaatt gatatcgtca
    18901 tataattgaa tatcacgttc tgtcatcaaa ttaagttcat ctacagttgt tcgtttattt
    18961 ccattttctt cagtaatttg caaataaata tttcgaacta agtcactcag cgtctcgatt
    19021 gagagcaaat catatgctgc actgttatat ataattttga acccgtgttg atgtggaaaa
    19081 atttcaatat ccgctaaaga tgtatgtgca tcatgtattt gatgtacatc ctcaataaca
    19141 tcattacaac aagacatcat atgatgataa caatgaaaaa tagtctctag tgaaagcgaa
    19201 gacttcgcgc actgtaattg cgacatattt tgcaacacac atttattaaa atctgttgta
    19261 aaacgttgac atacatcttt tgcatcgatt gttaacgtta acggcacaat atttccgtgt
    19321 aaatcatttg gtaaatgtga tggtacatgt atacctaatg tgacatcatg ttgttgactc
    19381 attatatgat tagctaaata cacactaaca gccaacgatg ccatatctat tgatgtcata
    19441 tcatcaatca aatacgtttg atataaagct tgttcaaatg gatgcttaat tggaaaataa
    19501 ctatcaatat ggatgtcaga gttattctct aaccgaaaat agtttgagtc taatgctata
    19561 tgcgatgcat cttgattgtc tttatcatca tttctattta tatgtgcatg ctgtcgagta
    19621 ttgttaataa cagtattgcc acgatatgca ttgcataaat catcaagaaa aatatcaatt
    19681 tgactatcat cgaaaatgga cacatgaaaa tctaatagta tatatgcagc atcagcgaac
    19741 tgaaacaatt taactttgaa taaaggtgaa tcattaaaat ggtaagtact taattcttgc
    19801 ttaaaaaaag cttctaaatc atagtttgcg gaagaagatg gaacttgttt tatctcaata
    19861 aaaggcagaa attcatgaag tatcattgtt aaattgtcat cggtagtaac atcaaaaaaa
    19921 tgtcttatag atgcatgttg ttgcacaatt gtcgataatg catacatcat tttagtagct
    19981 tcaacatttt tagcgagttt aacccaatac gcattacggt gtgtcgttga ttctgtatta
    20041 tttttgtata tacgaaaata ttcctgttga aatctcaaat tacccataat cataaaaagt
    20101 ccttctttca tatcataata ctcattactt actaaaattg catgatgata tgataaccga
    20161 cgaaatgtta attaactcgt tatgtaatga ttaatataaa acaccattcg caacatatga
    20221 gcgatatatt ctaccctaaa atacatcttg tatcatcgtt acaattggta tatttttcaa
    20281 tgtaaattac atacatcttc gataaatagc acactacaac tcgttaatca ctttctgttg
    20341 ttcatatctc attgcaaatt caatattgtt gttacaaaat atccatgaag caagtttata
    20401 ttaaacaaac aactcgcata aaacaattgt tatccttaaa ttttaacaaa ttcttaataa
    20461 atttatctct attttaatta cgaccaaatt aataggtttt caatataaaa agatgcataa
    20521 aataaatatt taaataaatt caatttgtat tcacttgttt ttgtcccccg aatacaccag
    20581 caacaagcat gctagcacca attgttaaaa cgataaacat atacagtccc atttgtaatg
    20641 acgttaagaa aacacccaac acaatcccta acctagctag tgtttctgaa aaatgaatac
    20701 ctaatgcatt aactgcacta tatgttcctc ttttagcttt aggaataatt ttaaagcgtt
    20761 gttctgaaac tataggcgaa taaataatct cacctacagt cgcaattatc ataaaaacaa
    20821 ctaataagcc aaactgatta agataggtta gaccactata gccaacaata taaatcagca
    20881 aaccagtgat taaagctttt ttaaaatcta ttttcaatac aactttcgag attgaatacg
    20941 tgagtaaaat gacgacgacc gtattaatca ttagcaagat tgctaacatc ttagcacctg
    21001 taatatcata tgaacctata cttattgttt caaactgatc ctttagtcta atagcaatat
    21061 atgaggagat tgaaaattca cccatcatga tgatactgaa ccccgaaatc aataacatat
    21121 aattacggtc tttcaaaact aatttataac tgcgaaatat attcattatt tgtaattttt
    21181 gataacgact tgcatgcctc ttgtcatcac tttgctttac ttgatttcgg tcttgaggta
    21241 accaaatata taaaataaag agtacaatta aaaatataca agctgctatt aagaaaagta
    21301 gtaacatact gtagccatac atcaagccac ctaacaatgc cccaatagct accgataagt
    21361 tcgtcatcca atagctaatc ttgtaaatat aatgttccac gtcttcggta attgcatcca
    21421 taattaatgt gtccataact ggaaattgta atccccaaac gattgtaaat atggcatatg
    21481 caacacaaaa accaataatt tgccacaatt gatgtgaccc aaatacgccc atgaacacaa
    21541 gcattatcac catcgtcgct tgataaataa gtactagcaa ctttttcgga aaaatctcaa
    21601 taaggtaacc agatataatg gacaatggaa attttagaac cactaaacca acaagatata
    21661 taccgacaat tgattgactt aacatatctg ttaaatatag tgctataaac ggtataaatg
    21721 ctgtcgtaat aattagctgt aaaaaattgc taatcaatcg tactttcaaa gtcgtactta
    21781 agcgtttcat taataactac acccctatcc acatatatac acactaccat ttatataaaa
    21841 tctattatta gattatacgt tgaaacaaag aatttttagt tatacaaagt tatttaacaa
    21901 acaaatgcat cgattttaca atgcatcttg catataatgc ctcaaaaaaa ttagcactat
    21961 atgactatat attattccaa atgaatgaaa tttatcaata attgcgtaag tgaacacata
    22021 tgtgcgtaaa tgttaaatca ttgtcctaac atagccgtga ctatacttag atgtaatcat
    22081 aaaaaaacta ctgccatctt tacaacagca gtagtgctta tatgattcat ttatataaaa
    22141 ttgaaagcgt taatcgctag cccagcatcc ttattctatt tagctgtata acttttacta
    22201 gcaatacgac cacttgcaac aataatatct ttatcttgga aaggttcatg attgaagaaa
    22261 cgctctaaaa tatctttaac tccatcttca atgcgttttt gtgcttctaa agtcatacct
    22321 gaatagtgaa ccgtcatagc atttctaggc attgttctcc atggatgatc agcaggtgca
    22381 ggttgtggat accaaacatc accagcatat ccttgtaaat gctcggatgc taacgcttca
    22441 actaacgcat cgcgatttac aattttacca cgtgcagtat tcactaaata actgtgtttt
    22501 ttcatacgac ttaaaacatc tttatcaaat aagttatcag tttctggtgt taatggtgca
    22561 tgaattgtaa tcgcatcact tgatgaaaca agttcatcaa agcttacaaa tttagacaat
    22621 ttatggtctt gttgattgat tggatcatag tgttgtaatg ttacattaaa tggcgctaat
    22681 ctttcagcaa caagttgtcc aattcgacca aatccaaaaa taccaattgt tttgtgttgt
    22741 aattcatgcg catgattacc tacttgagac aagttccatt caccttctac tgattgacga
    22801 tgaccttctt catagtttct aagaagtatt aataaatcca taaccgcatg ttctgccaca
    22861 ctaactgtat tacttcctgt aacttcaacg acaccaatat tgtgttcact tgctgccgct
    22921 aaatctacat ggtcagatcc tacacctgct gtaattgcta atttcaagtt cggtgctttt
    22981 tcaatacgtt cacgagtcat atatgcagga taaaatggcg cactaataat cacatccata
    23041 tctggtaaat gtttatctaa gtcttcacca ttatctgcta atataatgaa ctcatgtcct
    23101 ctttcctcta aaaatgtttt taatcctatt gcttttttag tattaagtaa ttgattttct
    23161 tgaccttcta ctgcttctgg aaataatgct acgattttca tatccatctc tcctaaatga
    23221 taaattttga cttccttaaa gtacgtgttg catgttgctt gttttaaaaa tatgacaaaa
    23281 aaaacggcac cgtttgacat accaccccct tgaattattg ttaaattcaa agcgaagtta
    23341 gcaaacagca ccgtgtacct tacaccagca acacttattc tattgactta tcgaaaacaa
    23401 atattgaaat gacttcatca tcattcaaat caatatctgt aaataatttt acaaacttag
    23461 cgcctacaag actttccatc tcatttacat ctatttcttt atacatctgt ttaatcttct
    23521 ctgtgcgtgt ataatggagc attgattcat tgcgtttgtc gtttaggtaa aaactctcaa
    23581 ctttactcaa aacacctgtc atatgtgcaa tcgcccaatt atctttaaac gacactcgaa
    23641 tactattggg tcctttaccc acgtattctt tacgataaga tcttactaga ttcgagaatt
    23701 gttgttcttt agtatgcgta tctatagtat tcaccttctt taaaataaga agttcattaa
    23761 ttgttcacat tttcattata caccttatta acactttttc aatgataacg attattatta
    23821 ttacgaaatg tatattttcc tagttaaaag gatataacaa attaacagaa aatgtttata
    23881 aactaagatt tatattattt taaaaaatgt ttcaacaaac gcatctaaac aaaaaatcag
    23941 cttatcacac ttaccccttc aactctgctt caagtttacc taaatgtctt aatgtcggcg
    24001 ttaatgctgc gaagaagaat ccttctttta acttgcgaac ttgtggcgaa tatggtgtgt
    24061 acgctcttga accaccattg acgacagaag cttgatttac atctaacaat aaatagccaa
    24121 tgtccttctt caatgatatt aattcactta aatgtgaagt taagttaccg tcatctaata
    24181 ttgcataata ttcctctcta agttgacgat aacgtttttt aaaagcttca acatcatact
    24241 ctaaatattg atttattccg ttttgcgcat ttgaaaatgc atcaattaac tctaaagaac
    24301 ttttaattga gcctaatcct attggaattt ggtaagcaat aaattgcggg cgaatagttg
    24361 ccgcaaactg cttcgcatca tgcgtgatga tttgtgattg tggcactacg acttgattca
    24421 atgtgatttg atacgttgct gacccgttga cccctaaaaa attggttttt tcaacgagag
    24481 tgataccatc ttgattggca cgtagaatga acatgacaaa ttcatctgat gattcatgtt
    24541 tcgaaatcgc accaaaataa tggtcttctt gaatattact tacagctggc atacgtccac
    24601 tgacaaccaa ttgtccatca acataagtgt gttcaaggtt caacttttct aaatcattaa
    24661 atgacttcat cggattagac aatccggtag cacctaatat ttctccagat aacaattgct
    24721 gttgtaagtc attatttaaa tgtggctgcg tggcattttc taaatacgtt gaaaaagcta
    24781 attggcacca taaacaaaat cctgttgtca aacaagactg cgatacagct tcgattactt
    24841 cagcattttt tctcaatgcc gcctcaccga aataaccatc tacaaataat tgttgaataa
    24901 atgttctcgg ataatacgtc ccttcatcaa cttctactaa atgaggatct aattgttctt
    24961 tgataagcgt ttctaaagtc atcatcatct ctccttattc accaaatctt ctaagtataa
    25021 actgctcaat ataactaatg aatcgatcaa taataaaacc aaataatccg ataaagaata
    25081 ttgctgctaa aacatcttct aagttcaaca tatttcgtgc atcaacgatt aaaaaaccta
    25141 atcccgattg tgcaccaatc atttcaccag aaactaaaaa tatccaactt gttcctaccg
    25201 ccatatgtat cccagccatg atttgtttaa atgccccggg aaataatata ttgcgataca
    25261 atgaccaccc agttaaattt aaatttgccg ctatttttaa atattgaggt tcaatgtctc
    25321 taacgccttt aatagtattg aacacaattg ggaaaaaagc agcgataaaa ataatcgcaa
    25381 tcgctggcaa actaccaata ccaaaccata gaacaacaaa tggtgcccat gctatcggag
    25441 atatcggtct aatcaattga aatagcggtt cgatagtgtt gtatagccaa cgattccttc
    25501 caagcaagaa gcccaatgga atagcaacca acaatgcgac aacaaagccc gctacaaatc
    25561 tccataaact aattgctaaa tgttggaaaa tttctccagt aacaatgaaa gtccatatac
    25621 tttttcctac aagagcagga ccaggtaaca atacaggttg gtaatgccca ataataatga
    25681 ccatttccca aatgcctaag aaaataataa atgtgataat aggtaatata aatttgttat
    25741 ttgtgggacg tgtcatgaac gcgatgcctc cttatacaat gacggttcaa caaagtcatc
    25801 atatgcaggt ggattaaaca aatgatgttg ttttaccaat gtcgtaattt cttgatagcc
    25861 ggatggctta attgttaaat caccatagga tgtccatgcc gctgactgtg ttaaaacgtc
    25921 acgactttgt ttaaaatgat gcgtcataat gtctacactt tgcttgcgat cattcatttt
    25981 aaagccagac tttttataat cttgtacaaa tgcttgcgct acatccttgt gttgatcaag
    26041 caattcccct ctcagtacta gcacacagca atacgcatca ggtataacgt catcaccatg
    26101 tttcaaagtc ttacctttgc ctaacttttc acccagtgca ccgaatggtt cggctacaga
    26161 ataccctgta attctgtgtt cactcaatgc ggctggcatt tctgctggcg acatttcatg
    26221 atagctaaaa tgccccggtt taatctttaa ttgtttacgt aattcctcaa gtaaaagata
    26281 atgtgttgaa taacgatgtg gtataccaaa atggtaatca tcgccattat taaattcatt
    26341 taagtgcata cctttttgtc ccataatgac attgccttca tgatggccca atgccacagc
    26401 ctttatattt gagcccttct gttttgattt catcgctagc tctattaaag ttgatgcacc
    26461 atcaatacga ccactgttta atgcgtccat taaatctggc caattattga atttaactaa
    26521 ttctagttta tatttcggat gattgtattg tgataataat tttttagtca tcatcaaatt
    26581 agctgaatgt gtaatcggca aatatccaat tttaatcact tgctgatttt gggcattttt
    26641 agacggttct ttagacgtcc tttgccaatc acatcctgta attataaaga ttccaatgat
    26701 gacgattatg cttaaccttt tcatcgtcac tcactcctta taaataatat tcaggttcaa
    26761 cttgatgatg attcaatgca aatgtttcca taatttcatt acgaatctta agtaggtggc
    26821 tatcattacg actgcgtgga tgtgatgctg taatttcata ttgagaaata atattgcacc
    26881 cttcacctaa cagaacaatg cggtcggaaa gataaatagc ttcatcaatg tcatgcgtca
    26941 ctaaaataat agttgattgc gttttatgtt ttagttgcac tagttgatcc tgaagtttat
    27001 aacgtgtaaa tgcatctaat gcacctaatg gctcatccat caatataacg ttaggcttat
    27061 gcacatgcgc tcgacatagt gccacacgtt gtttcatacc cccggacagt tgctcgggaa
    27121 aatgctttcc cctgtcttct aaatcaacta atttaagctg tgcgttaatc tcttcatcac
    27181 taattttctg ttgaaatcca atcctaatgt tgtcattaat cgttttccat ggcagcaaat
    27241 tatgatgttg aaatagcatt aaacaatctg gagatggctg ttgtttaatt tcgttatcaa
    27301 taatgacacg accagacgat ggatgaataa atccaccgat aacattgagt aaagtagact
    27361 ttccgcaacc acttttccct atgaaagtga ctatttctcc cttgctaatg tccaaattaa
    27421 agttatgaat tactttatgt gatccaaagt gatgttgtaa ttgttgaatt ttaatcatga
    27481 caagccccct tttaatccct actattttaa taggaattaa gtgtatatct aaagggctat
    27541 gccaaacaca gcccttatat cgtgaattgt tatatctata gatgattatg gtttggtatg
    27601 agtgctctta taacataagc gttattcaat taacgacgtt atattaattt cagctctact
    27661 aaatttcaat aaaatgattg ttttagaaaa tacttgcatt tagttcatta gtttcttcat
    27721 atcaactact tacatttata gcattgagct attctaatta actgcaatcg aaatccacgt
    27781 caaacctata tacatatatc tcatcaactt gttgtcttat taaagttttt cgatgccatc
    27841 aatcggtgta tcaactgctt ttcgcgcgcg acgtaccgct tcttcatcag gtgcgttgta
    27901 taaacaaata catttagaca tatcttcaca tacatatgtg cgtttaaatt caacttctgg
    27961 cacttcttca taatgaacag aatttttctt tttacgtgct aaatattgat ccatcgtaat
    28021 gccttccgga atgttccaag ttacaaggta atcaacatgt gcatcaccat ttttaacttc
    28081 atctaaatct ttaccaacta agcgtacttc tttgactaat tgaatactaa tatctgcttc
    28141 tgttaaaaat tgtttagctt ctgcttcgtc atttgcttcc acaataaaat aaccatgagt
    28201 taaattttca gtagcttgta cttcaattaa tgttggaatt gtcttcgtag atagtgatgc
    28261 tgcctttgct tctagttctt ctttcgttga tgcaaaatca agattgttag cttctaataa
    28321 aaataatgtc attaataaga cctcctataa caatggttga aaaaatatta ctataattct
    28381 tatcggatta caaggatatt gagcgatttt tttaaatatt tagataaaat tctgtaaaat
    28441 atattttcaa agagtataaa aatcatgtta gggtataagt aaataaacat atatataggg
    28501 ggctatcatt atggataaag aatctgtcgt agcaagttta gctagaaaca aaaagattgc
    28561 tgtagaaaca atggccggtc aaagatacat catagaacgc attttacata caaatgatga
    28621 aaaacatatt catattttga aacctaaaga tgtcgtgtta gatgtagata gcatcaaaga
    28681 aattgacgaa aatcatttaa atgatgcaac ataatccaaa acaaacgtgg gagtgggaca
    28741 gaaatgatat tttcgcaaaa tttatttcgt tgtcccaccc caacttgcat tgtctgtaga
    28801 aattgggaat ccaatttctc tttgttgggg cccacacccc aacttgcatt gcctgtagaa
    28861 tttcttttcg aaattctctg tgttggggcc cctgactaga attgaaaaaa gcttgttaca
    28921 agcgcatttt cgttcagtca actactgcca atataacttc gtagagcata gaacattgat
    28981 ttatgtccca gcctgtacaa tgttttattt atgttaattt gtcgaagtat ggctcatcta
    29041 atggattcaa ttgcaagttt tcaatttgca acgttgaatg tgcaatgcca tatttttctt
    29101 tcaacaatga tgatacttga tcaatcgctt gataatcatc accctcatat tttttatcta
    29161 acacaacatg ggcacttaat gaataatgct ctgttgtaat actccacaaa tgaaattcat
    29221 gtacatctaa tatgccatct atgtttttaa tatctgccat aatttgatca gtatccaaat
    29281 gttgaggcac actttccatt aaaattaacc acgcattacg cgtaatttta taaccaccac
    29341 gtaaaatgat gagtgaaatt acaatactaa tgattgggtc gatgatgcgc catcctgtaa
    29401 agtaaatcaa tacaactgca acgatgacac caatagagtt caataagtct cccatgaaat
    29461 gccataatgc actttgaata ttgatattgt cttcttgttt taaagacctt acaaggataa
    29521 ttgtcaaaat aatattaacg agtaaaccaa tactagcaat cataaacata atgccacttt
    29581 caattggttg cggataaata atacgtacaa tagcttcata taaaatccag attgaaatta
    29641 caattaatgc taaaccattt aaaaatgcaa ctaatatctc aaatcttaaa tatccaaatg
    29701 tgtatcgtgc agtcggcttt ttacttgcaa aataaatggc caacatagat aaaccaagtg
    29761 ctaatacatc actaagcata tgaaatgaat ctgacagtaa tgccaatgaa ttagatacta
    29821 aacctccgac aaattcaatc actgtaaata acaatgtgat gattagtgat gcccacagcg
    29881 tctttttaga actttgttga attttttgat gattgacatg atgaaaatat ttgtatctgt
    29941 ttatcgtatt tgcctttttc ccattcatac gtttgccact cctaaataaa tgcgtcgtat
    30001 ttaatattgt cgcttttaaa aataattctt tatagcttct cagattaata ttaatgcttc
    30061 cgtaattaac catgatttat acatcatcgt cctttacatg acaactcatt aatctttacc
    30121 ctttatacct ttatgtaata tcaccttgga aaaactttta cagcacattc gctctttact
    30181 ttatccctat catatagaaa attttaataa tgtacgagat tattgtgtta gttacataaa
    30241 aatgacaaaa aagtatctca aatttattgt ttagtttcat taagttcaaa aaatcacaat
    30301 aactttaatg attgttccac atattaaaac aaacgatgac tttgcatatt gaacttcata
    30361 tttctaaatc accacaattc ataaacaact ctgtccttat aatagctgca tcgcaaatta
    30421 gcataattaa aaacagcagt aagatgattt gcaattaaaa accatcctac tgctattatt
    30481 ttagtcatta tatcctaata tcatgatacg tgttcctata tattttgttt tgcttaaaat
    30541 ctaaacaacg ccgttaaatg ttaagactta ccgctagact gacctacaaa cacgcttcag
    30601 aaacgatatt tattctagta caaacctttt aaagcattgc ttgtatcaat ataaatattt
    30661 ttaacttgtt gatagttact taacgcacct ttataagttt ctcgaccgat acctgatttt
    30721 ttataaccac caaatggtgc gccttctggt acttggttgt aagtgttaat ccaaatacgt
    30781 cctgtacgta cagctttagc aatatttaat gcacgtgtga tattttgaga aaatacaccg
    30841 cctgctaaac catactcaga atcattagct atatcaattg cttcttgatc gtccttcact
    30901 ttaatcactg ttaacactgg tccaaatatt tcttcttgtg ctaatttgtg atgattgtct
    30961 ggcacagcaa ttaatgtcgg ctcaaagaag aaccctttat ctaatccatt ttcagttaag
    31021 cgatgaccac ctgctaaaat ttgtgcatct gattcttttg ctgcatcaat atatgattga
    31081 attttatcta attgatcctt accagtttga ctacccattt gtgtagcttc atcttgtgga
    31141 tctccaactt taatatttga aaatgcctct tgtaaacgtg gcaccaattg atcataaatt
    31201 ttttcatgaa ctaataatcg agaacctgca ctacatactt caccttggtt gaataaaata
    31261 cctaactgaa taccttcaac tgcaaggtct aaattagcat catctaatat gatattggcg
    31321 cttttaccac caagctctaa tgtagcgggt actagatgtt ttgctgcagc ttcggcaact
    31381 tgataaccta catcagttga gcccgtaaat gataatttat ctacaccatc atgattgaaa
    31441 attgcattac ctgattctga acctttaccc gttagtatat tgacaacacc tttaggtaat
    31501 acctcttgga aaattttagc aacttccaat aaacttaatg gtgttgaaga cgaaggttga
    31561 atcacaattg tattacctgc agcaatggct ggcgcaatct tccatgcagc taatagcatt
    31621 gggaagttcc aagcaacaac agcacctacg acgccaatcg gctcatgtcg tacgatactc
    31681 attgtgtctt tatcgatatc atttactgta ccttcttctg tttcaataac acttgcgaaa
    31741 taatggaaat gtcttgcagc aaatggaata tcaattgctg ttgtctcacg aatcggttta
    31801 ccattattta atgtttcaat cattgcaatt ttatcttttt gtgccattaa tttatcacca
    31861 atatcacgca acatttgtgc acgttctgat ttagaagtta atgaccatga ttcaaatgcc
    31921 tcttgcgcca ctttgactgc atgatcgaca tctttatctt ttgctcttgt aatatgtgat
    31981 agtgtttctc cagttgctgg attagtcact tcgattgttt cgtcactgct acctttaaca
    32041 aattccccat tgataaataa accataattc tctgcaatat aatctcgaac gtttactgcc
    32101 atattatctc tcctttgttt attggctata atataaatct cttagcatca tatttaataa
    32161 tgcttttaaa cgatatgatt cacattatat agtaagcgtt tacattttat aaaataatca
    32221 gctcacagaa gtctcatttt taaaactttt gcgtcgtttt tgcacataaa aataatctta
    32281 ttttcgaaaa catattgcac ttttcaaaaa taaaacacat aatataacta taatacttga
    32341 gaataattct cattaaatag tttggttgtt atgaaagtcg cgcttaaaat gcgttaatgg
    32401 gacaagaata attcaacaac gtttcatttt actgagtcat tgcacttatc atacacatta
    32461 tatttagcat gagttatatt actaaaacaa tattacatgc gcattagtac tagaatggag
    32521 ttttttcaat gcgacttatt ttaatcgtta ttggcttaat atttacagcg cttggtattg
    32581 caggtgccgt attaccttta ctgccaacga cccctttttt actcgtagca gttttttgtt
    32641 ttgctcgaag ttcagatcgg ttttacaatt ggcttattaa tcaaaaaatt tataaagaat
    32701 atgtagaaaa cttttattta catcgaggct acacgctaca acagaaaatt aaaattttaa
    32761 ttagcttata cattgtaata ggtttttcaa tttatatggt ggatgttctt gcagtccgtg
    32821 taggattaat cataatggtt atcatacaaa ccgctgtact ctttacattt gtaaaaacat
    32881 tacccaaatc aaatcataaa atagaggagt gattgcccat gtttatggca gaaaatagat
    32941 tacaattaca aaaaggcagt gcggaagaaa cgattgaacg tttttacaat agacaaggca
    33001 ttgaaactat tgaaggcttc caacaaatgt ttgtcactaa aacattaaat accgaggata
    33061 cagacgaagt taaaatctta actatttggg aatctgaaga tagctttaat aattggttga
    33121 attccgatgt atttaaagaa gctcataaaa atgtacgttt aaaaagtgat gacgatggac
    33181 agcaaagtcc aatattatca aataaagtat tcaaatatga tattggctac cactatcaaa
    33241 aataaatata ttaaaaaccc ctagtcaccg ctggttgtct aaaccaactt catgattagg
    33301 ggttttttat tatttgtgac gtaaaggtac gaattcatcc ggcttgtctg agcgcaatcc
    33361 aaaataatat tctattgctt cacaaatacg tcgtgatgct tgtccatcac catatggatt
    33421 attcgcttga ctcatacgtt gatacgcttc atcatcctca atcaattgtt tcacatttcg
    33481 aacaatattg tcataatctg tgccaattac tctcgatgtt cccgcctcaa cgccttcggg
    33541 acgctctgta tgattcctta ataccaacac aggttttcca aatgtaggag cctcctcttg
    33601 aataccacca gaatctgtca gcacgaggta cgattgattt gtaaaattat ggaactcaat
    33661 cgcatctaat ggctcaatta attcaatccg atttctccca gataaatatt tttcggcaat
    33721 cgctcttacc tttggattac gatgcattgg ataaatgaag acaacatctt tatattcatc
    33781 tgccaaatct cttactgctt taaaaatctg atgcatcggt tccccaatat tttcacgacg
    33841 atgcgctgtt agtaaaataa ctttcttgcc tttatgttta ttaataatcg ttgaaacaaa
    33901 atcattttga actgttgttg acaatgcgtc aataactgta tttccagtaa taaagatacg
    33961 ctctttgtct ttgttttcaa aaagtaaatt tttagctgca attactgttg gcgcaaaatt
    34021 caattcagca atattactta ccatgactcg atttaactct tcaggaaatg gtgagtattt
    34081 ctgatgtgtt cgaagtccag cttctacatg tccaaccgga atttgatgat aaaatgctgc
    34141 caaacttcct acaaaagtcg ttgtagtatc accatgtact aaaatcatat ccggctgttc
    34201 ctcattaatg atgctatcaa gtttagcaag cgcattcgcc gtaaggtccg ctaacgtttg
    34261 ttgatcttgc ataatattta aatcatgatc agcttgaata tcaaatatac ttaacacact
    34321 atctaacata tctctatgtt gtgctgtaat cacaatgttc gcttcaaagt tcccattatg
    34381 atcaatttct tttactaatg gtgccatttt tattgcttcg ggtctcgtac cgaaaataac
    34441 cataattttt ttcataacat tatcctctct gaagttcaaa cacatgacag cttatctttc
    34501 cttaatcatg tatgccctag tttgacacat tttatttgtc gataaaatta aatatattgc
    34561 cataattata atacgataca tcttcaaatg atgatttcac aacatttttt gtatcaaaaa
    34621 tcactttatg cttcatttta tcaaaatgac tgtccgataa atttttaaat tctgagtggt
    34681 cacttaaaat caatactagc gatgcgtctt tgacagcatg tgacatatca tgttccacaa
    34741 aatctaattc aacatgtgga tcataagcac atacttctat gtctggttct tgatttaata
    34801 gctcataaat atcaaatgct ggcgattctc ttatatcatc aacatcacct ttataagtta
    34861 aaccaaatac tgtgacttta ttcccgctca acgctttgat gatttgcttc gttgtatcaa
    34921 caacataggc cggcattgaa ttattaattt cacgtccagt ttgaattaac tttgcatttt
    34981 cagggtcttt agcaataata aagtacggat caacagctaa acaatgaccg cctacacctg
    35041 gaccaggttg atggatatta acacgcggat gtttgtttgc catttcaatc acatctaata
    35101 cattaatatt taagttattg caaatttttg ttaattcatt agctaaagca atattcacgt
    35161 ctctatatgt gttttccatt agcttactca tttcagcagt acgtgcatct gtttcaatca
    35221 tttctccctg aacgaatgtg cgatagacat atttacccgc ttcaatacaa gctttagtca
    35281 caccgccaat gatacgattg ttatgaacta attcttctaa aatttttcct ggcagtacac
    35341 gttctggaca atgcactaaa caaatatctt cacctattgt aaatcctaaa ttttcaatga
    35401 ctggttttac aaaatcatcc atcgttttag gcgcaattgt cgactctaca ataatagtat
    35461 tccctttttc taaaaatggt aaaatactat ctaatgcacg cataactagc gaaatgtcac
    35521 atgaccggta ctgatcatca ttattcggcg tcggaacggc aatgataaaa acatcagatg
    35581 cttctggcgt tgtagatacc ttcaattttc ccgatgacag tacctcttca taaacctctt
    35641 gtaacccagg ttcttcaata ctaatttgac cactttgtaa cttatcaatc gtttgctgat
    35701 taatatcaac accaagcaca tcgacgccat gctttgcaaa cataattgat gttggtaaac
    35761 caatataacc taagccaact actgttaact tcatactata acctccaaat aaaacgattt
    35821 gtatgttgat tttatttaat agatgactta tgccttatct ttggttgtcg tttcatccat
    35881 gatgtccgca ataacaagtg acatttttcc aggaataact tcaagtgcat tattattttc
    35941 atataacgta ttgctgtatg ttaaattgcc gaataatttt ctaaagaccg acaacttatt
    36001 aaaatactta tttaacactg aaggcatgtt gatcaatacc gttttacgat gtgattggcg
    36061 acgtatttca tacattactg acgatgtatc aaagtaaaaa ctatcttgag gatgatacac
    36121 gcctgtcact tctaatgata ttaattgatc aataaatgct gtcagatgtt taatatataa
    36181 tgcactgcgc tgattgttaa tattgggaat gattggcagt cgctttgaca attgcattaa
    36241 ccgttggaaa tttcctgggc aatgtgcacc ataaatcatt ggtggtctca caattgctac
    36301 tttaaacgaa tcactaatca actcttgtaa tgcttgttca gcgaactttt tggaaatacc
    36361 atagttggtc gtagggttca ttggtgtttg tgtatcaatt tgatctgatt taccaacctg
    36421 accttctttt ccataaactg ccatagtact cataaaaata aattgtttaa cgtcttcagc
    36481 tttagccttt tgtgccaatt gtttcgtaag caacatattc acttgcatat aatcagatag
    36541 ccttgcttga ggtgaattgt tgtgaaccaa agctgctgta tgaattaaaa catcataatc
    36601 tttgaacgag gtcgacttcc ataattgatt cctaacatta atttgatcta cttgatgtcc
    36661 ttgttcaata agcttatctt ttaaagcatt accgatatat ccatgtacgc ctgtaattaa
    36721 aatatttttt ctcattagtg atgcacacct tctgaagtaa cgatattttt aattgtttta
    36781 tatatgatat acatatcaag catcatagat tgatgtgtta agtaataatg atcatacgct
    36841 actttttgat catcagtaat atcatctctc cccatcactt gagctagtcc tgtcacacct
    36901 ggtctaatcg tatgcacgtt cgcttttgta cgtttttcga ttaattcgta ttgattataa
    36961 agcgctggtc taggacctac aattgacatt tctcctttta aaacattcaa taattgtggc
    37021 aattcatcaa tagaggtctt acgaatgacc ttccctgtct ttgttatata cgatgttgaa
    37081 tccattaaat cagttgcaac attaggtgtg tctattttca ttgatctaaa cttataaata
    37141 ttaaacaatt cattattaat cgtcggtctt ttttgtttga aaatggctgg tccaggtgat
    37201 tccattttaa ttagtaatgc tgtaattaac agaatcggac ttaaaactac taaaccatat
    37261 attgaactca ctacatcgaa taatcgcttc ataattatct cctcacttca acagattgta
    37321 atacttcata gtattaattt ctctcgtata tttatcttta aacagttgat gtgcgcgctc
    37381 acccatctcg tgcaattcct tactcgagtg agtgttgatg aagttataaa tggcatgtgc
    37441 atcgccatta tcaatttgga tacccgcatc atattgttca acatgttgaa cgatatcaga
    37501 ttgcttatcc atgatgagta ccaacggttt cttagctgca aggtagccat aattcttgct
    37561 cggaacgcct aaaccgacgc cttctttaat cagcgatgca atacatacat ccgcaatttt
    37621 taatacgtca gcatagtctg tacctgttaa aaactcaaac attttaacat tttcaatacg
    37681 atggtcttct attgccgttt tgacatctgc aaatttctta ccatgaccac aaagtattgt
    37741 taacgtttga ggctgatcct tatttaattt taaaaatgag ataagtgtct ccatatcctg
    37801 taactgcccc atattaccgc tatacaataa aattttgtcg tattgctcac ggtaagcttt
    37861 aaatgtgtca ttatagatac gattgtcttg taattgacgc atgtcatacc agttaggaat
    37921 cacatggata ttgtcagcat ttttagaaat tcgatgattt agtaagtagt ttttcatttc
    37981 cgtaccaagg acaatgacat tttcagcatt cttgtagaca tgtctattaa tgtaacgcat
    38041 cagcttatca atcatgctac ctggacgagt tgcacctgtc ttaatcgcat tatcaggtgc
    38101 tatatcatac accacaaaag aatatttttt cttaagcagt ctgtgtaaaa cgtctggtat
    38161 taatggcaag attggtggat tagagtaaac aagaatctga tcatatttca acattttagg
    38221 tatattaatc acgaattttg aaaataaact aaagaaattg atgatccttc caaccttact
    38281 tttgttatta aacctcgaat acttgagacg tcgaatgcga attccacgat gcatctcggt
    38341 tttagaaacc tgtttatgat tactatattc atatggccat ccacacatga catcgacatt
    38401 aatgtgattc gcaattaaat cttccgccaa ttgagttggt aacgtcgcag aagatacata
    38461 ttccggataa aaatactgac ataaaatcaa aatctttttt tcactcatct aatcgacgtc
    38521 ctttttatta atgaatttag actttaaacc tataatattt aaaatcacat acttaataat
    38581 gttgctgaac agcgttgtcc aaaagaatcc atttagacca aacgcaattg tcattaaaat
    38641 agttatgaat ataaatgtaa tcgtgtgaag cgtcatataa ttcgcttgta atgttattga
    38701 tgcgtgtttt gtatttaaag tttggatcat aatactcact gcattgaata aaacacctat
    38761 attacctaaa ataataaact tcgaatataa acttgaatca atgttataca gtaaagagac
    38821 aataattaat gtaattggat aacatataat catgactaaa catagtgcag ctatagcaaa
    38881 tagattagtt ttcaaatatt gcttctttat attgtcgctt tcatttacag aaatatatga
    38941 aagtactaca ttattaatcg gatacagaaa tgtagctaac attttcccaa taaatgttga
    39001 aagaaatgat atagttacag ctgttccacc tataattggt aataagatta atctatctaa
    39061 gtagagattc aaattattaa ggctatttgt actcagtagc atcacataat ctttgaccac
    39121 attattatct tcactttgat actcgcctat agttaatccc cgtaatttaa ccaatgtata
    39181 tatcgttgca aacaattcac tggtaataaa acaaacaatc cagttttgga ttaaataata
    39241 tagaaatagt cctatcagca aacctaaaaa ttgaataaga gcaatataca aaatctgatt
    39301 atattttaaa gtcatcctaa aaaatacatt cagataaatc cttaaacaca ttaaaatatt
    39361 aagtagaatt aaaaagataa tatcgatggt gttcaaatta aaaaagtaaa gaaatacaat
    39421 aattaaagct atactctcaa tcagaattga aattaaaagt atcgacacaa atttccagta
    39481 gtaatgattg gatttgtata gattcatatt aattaatcgt atattgttaa gcgtattgcc
    39541 taatacaaca ctcgtgattg ttattattgt ataaatcgtt aaaatagaac caaacgcttc
    39601 attacctact cgttgattaa taattggata agctaaaaat tgtaatccta aagctataag
    39661 caacgtacca attattgtct ttacgctatc cataataaaa actttcttaa ccatgatgac
    39721 gccgtccttt tgtaataaaa tagaacaaca caaaccaaaa ttcacttaca actaaataat
    39781 ttgaactaaa cattaataat gtgattggat agattgctat aaacataacg agtaaatcta
    39841 tagtgtttgg atcatagttc ctaatcattt tataaactag tagcaaaatg caaatcatta
    39901 tgataaaaaa ccctaataag ccaaatgata gaatcaactc aataatgatg ttatgtggta
    39961 tatttccgat tagtttataa tagttaaatg gcccatagcc taataacgga ctttgttgaa
    40021 taaagtaaat acctttttca taaatcggtc ctcttccaga agtaccttct aaattaagtg
    40081 ttccaccttg tagatatgaa aatgttctag tattcgaacc ttttgtaaaa agaaagtaaa
    40141 tcaatacact agatatgctt aatgcaaaaa tatacataat gctttttact gcaataggta
    40201 ttcctctttt aaacgtaata agtataaatg caaataagcc gtaaagaatt aataaaatag
    40261 cacctccacg ccctcctggt ataaacacaa tagggatatc aattattgta aatagaacat
    40321 atatccactt atgtttcact gaacctttca taatgaaata aatgcctaat ccggcagtaa
    40381 atgctgaaag gtacgaagcg ttttgatagt tcataagtcc aaaattgata tagctaggta
    40441 tctcacctgt aagttttggt attaaaatta caaaaataaa tgaaatagaa aatatgaaaa
    40501 atactaattt aaaaaatctt tctaccgtag ccttgtttat atatttaata taaataccac
    40561 taattgccgc tggaactgcc catgttaaaa agaatagaat attattttta gctagtttct
    40621 cttccttatc tggtgaaaaa taataaaaag ctagataaag caaacatata gcaattaata
    40681 atattaaccc tcgcggaatt tcttgcgtga caattatctt ataaatagca aacaccgtag
    40741 taattaatgc tataccaacc atggttgagt aatacaccgg ctctataggg aaccctaata
    40801 cttctttagt aaatgtagag attactataa atatgttcat gctgataatt gcacaaagta
    40861 caaaaaattt catagtttac ctctctttaa aatttatata attctactaa tcgttcactt
    40921 tctatttgcc aattcaaaat tttagacgcc ttaattgcat tttgacgtaa atgattaaac
    40981 aaatcgtgat tatctcttaa ttttctaacc gccttttcaa tttctaacgg cgtaacttcc
    41041 tttaaaacaa tgccaaattt atatttttca ttgagataaa tatgctcttt gacaggagat
    41101 aaaattactg gtaaaccagc atgtatacat tcaaaaattt tattagatac tgtatattca
    41161 aaattaatag atacaggttt cgtcaagata acaccaacat tactttctgc taacttatca
    41221 accaattctt ttacttcaac tggtttatcc aacctaatat tttccgagtt ataactaatc
    41281 agttctttta tcacttcttc atgcggacca aaccctcgaa ttatgaatga aggagcattt
    41341 tgtttaaaag ctgatgaagc aataataaac tcttcatatc ctctgtccat tacaatttga
    41401 ccttgatata cgatttcttt aaagttttcg atttctttaa attctctgct atcatttaaa
    41461 ataggtgcat tcgtaataac attcgcttcc ttcttatatc ctttagattg ataatattct
    41521 tttgctgcat gacttactgt tacgaaggca ttaacacgat gttttactat gtgtttttct
    41581 atactttcta caaactttga aataagtgga actttattaa taaaggcatt tttcgcatat
    41641 atttcatgcg catcataaac aatattagct tttttataat tgcttaaata gaccattaat
    41701 aatacgtcga aatcatttgc atgaatcacg tcaggtttaa aagctttaat ttctcggata
    41761 acacctgttg caaatcttat acgcttaatt aatttagaaa gaatattttt gggatctacc
    41821 ttgctaccta acaaacgata attacaatct aaattttcca atcgcctatt agtagcttgt
    41881 gaattattca ttccaacaat tttataatca ttcgtaacgc ctttaattgt ttctatttgt
    41941 ttaagtaccc ttgggtcttg aacaatatta ctcgatacaa tatttaaaat tctcatatca
    42001 ttaagtatcc tttttattta aatattcaac cgaaaatcct tttagtttgt caggcgtttt
    42061 ctcccaccac ttgctttcca aaagtttttc aattgtttta ttgtcaaatc gcttcttaat
    42121 cacttttgca ggaaccccac caacaacctc atatgctcct acatttttag taacaactga
    42181 gccggctgct atgactgcac cagtatttat tgttaatcca tccataataa ttacatttgc
    42241 accaatccac acatcatttt taattgttgt acggcttggt tggtcattaa agtctataaa
    42301 cttttgcttt atgttaaatg gattattatt agaataaaaa atcggtgatg agctaaaaaa
    42361 gtgtgtagga tgttttccta acccaatttt tacatccgaa gatatcgaac aatatcttcc
    42421 tacttctaca ttattaaaat cactaccaaa tccaatataa ctgtattcac caatgtgaga
    42481 attcctgatt ttacaccatc tatctatata gttattgcca tcaaattttg agtttgtaat
    42541 atacgccaag cgatgaatct taacattcga ttctttagag gactggtttt tcagcaaacc
    42601 aattatcttt tcaatcgcta tcctcatcgt catttcctcc aagtatttcg attgataata
    42661 tctttatagc tttgaataat tttaactacc tttgtcgaaa cgttagtgtc tttataatca
    42721 atagcatcaa tcatcggttc gttattgttt tgcatctctc ttgctagttc aacggattgg
    42781 attagattgt tataggtaat accacctaca ataaccgtac ctttatctag tacttccggt
    42841 ctttctgtgg aagttcgaat aaggacacca gggaacttca aaatagacga ctcttctgac
    42901 aatgttccac tatctgatag cacaacaaat gcatcttttt gcaatgcatt ataatcaaag
    42961 aaaccaaatg gctttaactg tttaactaat ggatcaaatt caaatttact ttcttcaatt
    43021 ttcttccaac ttcttggatg cgttgaataa atcacaggca ttttatactt tttggcaata
    43081 tcatttatcg cattcattaa tgatttaaaa ttcttttcat tatcgatatt ctcttctcta
    43141 tgcgcagata ctaaaatgta ttgttgcggt tctaatccta gtttatttaa aacgtcactg
    43201 tgattaattt tatctcgatg cgcttctatc acttctgtca tcggtgatcc tgtcacaaag
    43261 atattcgctt tattgaagcc ttcatctaat aaataccgtc tgctatgttc tgtataaggt
    43321 agattcacat cactgacatg gtcaacaatt ttacgattga tttcttcagg tacattctga
    43381 tcaaagcatc tattacccgc ttccatgtgg aacacaggaa tctttaatcg tttagcagat
    43441 actgctgcta aacaactatt tgtatcacca agaattaaaa gtgcatctgg ttgttcgcgt
    43501 aataaaacgt catatgtctt cgcaataata ttccccatcg tttctccaag gttacttcca
    43561 actgcctcta agtagtggtc cggttgtctt aattccaaat catcaaagaa aatttgattc
    43621 aatgtataat cataattttg accagtgtgt actaatatct gattaaaata ttgatcacat
    43681 gctttaatcg ttgatgataa acgaatgatt tcaggccttg taccaactat tgtcattaat
    43741 ttcagttttt ccatgcgcta tacctccaag aaatacgtat ctggctgatt tggatcaaac
    43801 atttcattca cccacataat agttaccata tctgtgtcgc ctaaattttc aatattatgt
    43861 gtgtatccta ctggtatgtc tacaacttct aatttatcgc cagaaacgta atattcaatg
    43921 atttcatcat cattaacatg tctaaaacga attacccctt tacctgatac gactagaaat
    43981 ttttcgtttt tagtatggtg ccagtgatta cctttagtaa tacctggttt agaaatattt
    44041 acagaaactt gaccacgatc cggtgttttt ataaattctg taaaagaacc cctatcatcc
    44101 acattcataa gtaagggata actaaagtct gtactaggta gatagcttaa atacgtacta
    44161 tacaaatctt tttcaaacaa gttatctaat ttcggcaatg ttcgatcgag acgtgactgt
    44221 ttgaacttgt ataataaatc tacaatttct cccaatgtca ctttaaatac gtttggtact
    44281 gtaggtacac cattttcaat cgttggagtt ccttcaatag cacgctttat ttcagcgacg
    44341 atatcatcca cgtagtttag cgttagttca acattccgat cattaacttg aatctcttcg
    44401 ttacgtgcaa ttttgtaaca aaatgttgct atcactgagt tataattcgg cttacaccac
    44461 ttgccgaata aatttggcca gcgataaata taaaccgtat tgccatactc ttcggcatac
    44521 tctcttaata gctgttcccc ttgcaactta ctctcaccat aaggattatc ttgtgttgct
    44581 tgtattgaag acgataataa tatcgctggc tttttcgtat ttctagttaa tatatcaagt
    44641 acatgatcta aataactcac gtttcctaag ctgaattctt tgtcatgttc aggtcgatta
    44701 acacccgcta aatgcacgat aaagtctgct ttcaacaatg ctgactctaa ttcttcctct
    44761 ttagtttgtc gatgtacttc gaaaatatga tgatctgtcg ttgatgttaa atctgctttc
    44821 aagttttttc ctacaaaacc ttttgctcct gtaattacaa tattcaacgt caatctctcc
    44881 tatctcattg aagctttata atcattcaat tcgtttctaa catattctag tgttaaaagt
    44941 ttttctttta tctcttccac cgttaaaata tgtgtattat cggagttata ttcataagat
    45001 tgcgtaatct tttcgttacc ggtttcaaca taattactat aatttaaatc tctggagtct
    45061 gccggcactc taaaataatc acccatatct tcacattgtg cgtattcttc tctcgtcaac
    45121 aatgtttctg cttttttctc tccatgtcgc gtaccaatga tttcaattgc attatcagct
    45181 tcaaacaatt ctaataatgc ggtcgcaaga tcccctaccg ttgagcttgg tgctttttga
    45241 accataatat ctcctgtctc tgcatgctta aatgcatgaa caactagttc taccgcatct
    45301 tctaagctca ttaaaaatct tgtcatatca ggatctgtaa tcgttaaagg ttctccagct
    45361 ttgattttgt cgataaacaa aggtattact gatcctcttg aagccatcac attaccgtat
    45421 cttgtaccac aaataagcgt ttgttcacta cgaatatttc ttgatttggc tacgaatact
    45481 ttttccatca ttgcttttga aatacccata gcattaatag gatacgctgc cttatctgta
    45541 gataaacata tgactttttt aacattttga tgaatagcac tttgtaagac attttctgta
    45601 ccaataatat ttgtcttcac tgcctcaact ggaaagaatt cacatgacgg cacttgtttt
    45661 aaagctgctg catggaatac gtaatcaaca tctcgcattg ctgtttctac actttgacta
    45721 tcacgcacat caccaatgta gaactttaat tttgaattat tatatttttt tcgaatgtca
    45781 tcttgttttt tctcatcgcg tgaaaaaata cgaatttctt taatattaga atctaaaaac
    45841 cgtttcataa cagcattacc gaatgatcct gtgcccccag taattaataa aattttgtca
    45901 tcgaacataa ttatctccct ttttgccatt ggcatagtta ataatttttt ctttactaaa
    45961 gtcattgacg atgtcttgaa taatcgcttc aacttcatta catttcatat gttgtacttt
    46021 gccacgataa attttttcaa atacttgttc aggatgaacc tcatctttat tcataagctc
    46081 ttcaaacatt ttttcgccgg gtctaatccc tgtataagta atgcgtatgt cgtcttcttt
    46141 tttaccactt agcttaatta aattacgtgc caaatctaca attttcactg gttctcccat
    46201 atctagcaca aatacttcgc caccttctgc taatgcccct gcctgcaaaa ctagtctaga
    46261 agcttcagga attgtcataa agtaacgtgt catttcagga tgtgtcacag taactggccc
    46321 accttcttca atttgacttt tgaaaagtgg aatcacagat cctctcgatc caagtacatt
    46381 accaaatctc actgcaacaa aatttgttcg atgcgtttca tcatttaaac tttgaataat
    46441 catttctgca attcgctttg aagctcccat gacattaggc ggattaacgg ctttatccgt
    46501 agaaatcata acgaatttct ttacctctgc atttttagca gcttcagcag tatttttcgt
    46561 acctaaaata ttattatgta ctgcttcttc agggttgtct tccattaacg gcacgtgctt
    46621 gtgtgctgct gcatgataaa ctgcgtatgg tttatacgtt tccataattt caaacatacg
    46681 cgctctattt tgcacatccg ctataatagg aacgatatca acattttttc cgaagcgatt
    46741 tcgcaattca cgattgatta aataaatact gttttcacca tggccaagta gaataatacg
    46801 ttctggatag aaattacaaa cttgtctaca aatttctgat cctattgaac cacctgcacc
    46861 cgtaactaaa atagttttat tcgtcaattc atttgatatc atatccatat ctaattcaac
    46921 aggatctctg cctagtaaat cttctacttc aacttttttc agttgattca cttctaactc
    46981 accagacatg acgtcttcta tatttggcat tttcaataac tcaacgccat ccatatggca
    47041 aatattatta atttctttca aacgctcttg accaatagtt ggaattgcaa tgatgatttt
    47101 tttaatctta tatttcctca ctagttctgg aatatccgca attttacctt ggacttttac
    47161 accctcagta attgtgatat tgcgtttatg ttcgtcatca tcgactgcta ataccggttc
    47221 aagtttcatt tcgtcacttt tcaacatttg tctaatcagc attgaacctg cttgaccagc
    47281 accaacaact aaagttggct tcttattaaa tgacttacct ccaaggtatt tccgataaat
    47341 acgccaaaat aaccttgagc cacctattaa aatcaagtgc atcatccaag taattaaata
    47401 caatctaaaa aacggtctat tgcctgtaac aattgtcacg accaccatcg taataacgat
    47461 agatgtcgtc acagctttaa caattaaaat caattcactc acactggcat attcccacgc
    47521 tcgatgatac atattaaaaa taaatgctga aatatgatgc gatatgaata gtgatatagc
    47581 tgccaatatt aataatttga cagaatatgt tttgaaatac ggttctaaaa tgtaataact
    47641 tacgaatact gaaaatgtca ctatcagtga atcgattaat gctagtatta aaagccgcaa
    47701 tttcacagat aaatgtgcca taaaacccct catttgctgt ttataaccca aaccatcttt
    47761 tctgtttata atcttgttgt ggcattcgtt taggaatttt tttatcatca acaactaact
    47821 tcgcattact aataaatccg ttcatatctt cataataatc acgtaatttc ttatcattaa
    47881 ataagtcttt cattaagaac ggtctgattt ctgtgttatg cgcatctgaa ccgatgaaat
    47941 gtgtcagatt gttttcaatc atttgaattg ctaattttct aattttttta ccggaaatac
    48001 ccgctaatga cgccgttgtc acttgactta aagcaccttt gttaattaaa tcgtatagta
    48061 tgtcaaggtt ttgacttatt gctttattcc gctctggatg tgcaataatc ggtacaaagc
    48121 ctttactctg taattcgaaa aataattgat cagtatagtg tggaacttca tttgatggaa
    48181 attctattag taaatagcgt gaatcattaa taccggtaat aacttttcga tcaatatcat
    48241 taaggatttg atcggtaatt cttatttcct gaccataata aaactttaga tttagtgctt
    48301 gtacttcctc taagctttca atatggttta aacatgattt cactttttct ataggtgtgg
    48361 tatatcgagg atgtaagtga tgtgatgtta caatgatttc tgtaacactt tgtgttgtcg
    48421 cttgttttaa aagatccatc atctctgttt catttgtcgg accgtcatcg atattaggca
    48481 atatatggtt atgaatatca atcatactta ttcatctcca taatagtgat aataactaga
    48541 agatttatcg acctttgtct tgttcaaaat gacacctaga atgttactgc ctgctttttc
    48601 cataagtgct tttgcttttt taacttcatt tttatcattt ttttcactat caattactaa
    48661 cagactatct ttaatagcac gcgcatatag ttgtgcatca gtcacagtat taactggcgg
    48721 tgtatcgaca ataataatgt cgtaacgttt attaaacaga tcaactaatt ctttgaacct
    48781 ttcagaccca attaactcag atggatttgg aggtacaggg ccagctgtta gcaaatctaa
    48841 attttcaatt tctgtcgacg taattgcttc tgacatagtc gttcgaccaa tgattaagct
    48901 tgatagtcca ttattatttt gctcattaaa aatatagttt tgtgttggct tacgcatatc
    48961 gccatcaata actaatgtct tatagcctgc ttgtgcataa gtaatcgcta cattcgatac
    49021 aactgtactt ttacctgcac caggcttttc agaagtaacc aataagcgct ttacttcacc
    49081 atttgctttt gaaaacatga tgtttgaacg tatacctcga aacttttcac taattgttga
    49141 ttttggtttt tcatatacaa atagtgttgt tgtcgtattt tccttttttg acataagtag
    49201 caaccatcct taattaaatt tttgaattga acccaataca ggcaatccta attctttctc
    49261 tacatcttct tcatctttaa ttcgcttatc gaaaattact ttgaagaaga tatatataag
    49321 cgcgacaact aatcctaaaa agaatgcacc gattagattc actacagttt ttggtgcgac
    49381 tttaactgct gtaccgtctg ctttagataa aattgatacg ttatccacac tcataatctt
    49441 cggaatttgt ttacttgtaa ctttagcgaa gctattcgca attttttccg aatcttgttt
    49501 atgaccactt ttaacttgga tgttgataag ttgcgtattt tcttggtttg taattgtcaa
    49561 catactcgac aatttagatg gtgaatactt atcatttaag tcctttgaca cctcatctaa
    49621 aattctagga cttttaacaa tttctttata cgtatttaca agttgaatat tactttgaac
    49681 ctcttgtgcc ataaactgag gattgtcacc cttagtttga ttcactaaga tttgagtatt
    49741 agcttgatat ttaggtgata agacgaaaaa tgtaacaata gcgctaataa ttaaaaataa
    49801 tagcggtaaa ataattaaaa tcttcaagtt tttttgtaat acttctttaa tttttgttaa
    49861 ttctaatgta ctttccatta tttacctccc ttaaaaattt tcattaaaat tggtattata
    49921 tatatagtat ttacatatta catatcgttt aaacaattaa ttacttttaa accgcattat
    49981 ttacgcatat tcatttatat gaaattaaaa ataattatac tctaaagtag taatagtttg
    50041 cgaaatgagt atcaatctta atattttctt tatttaaaaa aatgattgtc tagtttgtat
    50101 ctctgaagat ttggcaataa ataaaagccg ataaccgtaa aatgattatc gacttaaagt
    50161 ttatgtggca ttttttactt ttgtaatttc aggtgagtta tatgattatt atcagataga
    50221 ttattgctta taatcatatg atgtttgaat gatatctttg atttcactga ttagtgcttc
    50281 tttaggatta gcagttgtac attgatcttc aaatgcgagc tctgccattc tatcaattga
    50341 ttcatttaat tcttcttcag acacaccttg tgatttcaaa ttcatttcaa ttccgactga
    50401 ttgacctaat tcgtagacag ctttagctaa tgattctacg agtgcttctg tcgtattccc
    50461 ttttaatcct aagaatttgg caatatctgc ataatctgta tctgctctga agaactcata
    50521 tttagggaat aatgcatgtt tttgcgggtc tttggcatta taacggataa tatgcggtag
    50581 taatatcgca ttcgctctac catgcggaat accatattcg ccaccaattt tatgtgcaat
    50641 tgagtgtgca atgcctaaga atgcatttgc aaatgccata ccagccaaag ttgatgcgtt
    50701 atgcattttc tctcttgaaa ctttatcacc cttttcaaca gatgatttta aatattcgaa
    50761 cgtcaattta atcgcttgta gactcaaacc tcttgtatag tctgaagcca ttacagatac
    50821 atatgattcc attgcatgcg ttagtacatc cattcctgta tctgctgtaa cgctttttgg
    50881 cacactcatc acaaattgag ggtcaataat tgcaacgtca ggtgttaaag caaaatcagc
    50941 caacggatat tttacatttg tttcactatc tgtgataact gcaaatggtg ttacttctga
    51001 acctgtacct gatgtcgtag ggatacaaat gaacgtcgca ttttcaggca tgcctatttt
    51061 ataagtacgt ttaccgatgt ctaggaactt ttgtttagca ccgaagaatg atgtctcagg
    51121 gtgttcaaag aacatccaca ttgcttttgc agcatccatc gctgaaccac caccaagtgc
    51181 aatgattgta tctggttgga aatcaaccat catttccaga cctttatata ctgtattagt
    51241 tgatgggttc ggttcgactt cgctaaatat tttaatttga ggctgttccg ttctttgtct
    51301 taatacattc tcaactgttt ttgtataacc gaattctacc ataccagggt cacagacaat
    51361 catcactttt tcaatcttgt ccattgttgt tagactcatg attgcatttt cttcaaaata
    51421 aatttgagca ggcaccttga aaatttgagt attattacgt cgtttagcaa tcgttttaat
    51481 gtttaataaa tctgtcgcac taacattatg tgaaattgag tttctaccgt acgaaccaca
    51541 acctaatgtt aaagacggaa tcaattcgtt atacatatca ccaatacctc caaccgctga
    51601 tggtgtattt acaagtacac gacaagcttt cattcttagt ccaaaatctt tttgtaatgt
    51661 ttcatcttct gtatggataa cggctgtgtg tcctaatcca ccaaaatgta gtgtgtcttc
    51721 acaaatttga aatgcttgtt ttgtagattg ggcttttact aaggctaata ctggagataa
    51781 tttttcacga gataacggat agtctgaacc tacaccgcta atttcggcta tgataagttt
    51841 tgtattttcg gggacaggta tacctgctaa ttcagctatt tcaactgcag atttaccgac
    51901 aatatcaggc ttaatacctg ttttttgttc attcataatt gcattttcta agcgttgtaa
    51961 ttcatctttt ttaacaaagt atgcttgatg tgctttaaat tcattagtaa catctttata
    52021 aatttcttta tcaatgacta caacttgttc agaagcacaa atcataccat tatcaaatgt
    52081 ttttgaacca atgatatcat ttactgcacg tttaatgtgt gctgtttttt caatgtaaga
    52141 cggcacgtta cctggtccca cacctaatgc cggtttgcca gttgaatatg cagacttaac
    52201 catgcccgaa ccacctgttg ctagaactaa tgcaatacct ttgtgattca ttaattgttt
    52261 tgttgcttcg atagaaggca cttcaatcca ctgaataata tctttaggtg cacctgcctt
    52321 cattgccgct tctaatacaa cttctgctgc acgcttcgac gattcttgtg cacttggatg
    52381 gaatgcaaaa atgattggat ttcctgtctt aattgcaatc atcgctttaa aaatagttgt
    52441 cgacgtagga tttgttgttg gcgtaacacc acaaataaca ccaattggtt ccgctacata
    52501 cgttaatcct ttttctttat cttcaccaat aatccctact gtcttattgt cttttattga
    52561 attccatata tattcagaag cgtataaatt tttaatcgct ttatcttcgt atatacctct
    52621 tccagtttct tcatgtgcta attttgctag caccatatgt tgatcaacag ctgctaagct
    52681 catttgatga acaatatgat caatttcttc ttgtgacttt ttagataatg cttctaatgc
    52741 ttttttccct ttgtcagcta gagcatcaat cataattgcc acttcttgtt ctttcgatcc
    52801 acgattttct ttttcaggta tagttaacat atacaaccac tcctttatac tttgtgaatt
    52861 atttcacaaa cattatagta catgtctctc aggatataaa gaaaattcta tacaaaaaag
    52921 tttaatttcg aatattattt taacaaatat caaattttaa aataaatgtt ttcatgaaat
    52981 cattgttatt tcgatgtttt tagaatgatt ttataatcat aattttttca atgacataat
    53041 ttattcataa ttttatattt aattctgaat attctttaat agcctaaaaa gcttgttata
    53101 tcgcacaaaa cacaacatta aaaggtcctt gtcgctacct atcaacagat gttacacaaa
    53161 aaaactcgaa ctgaaatgat gatcttttca gctcgagttt taaatattgg tgccttattt
    53221 atatagattc gttatattat attctctatt ttcattaaca taatccttaa agagttttaa
    53281 attaatacct gctagatgat tcaaaaatgt ttcatcgact tttaaataat tcaataattt
    53341 ttgtggtgtc agtatatttc tatcaaaata caactttaat aaactattca ttttgacagg
    53401 acgtgacatt tcaatcacgt cgtctaaagg ctctttactt ttatagcctt ttttatttaa
    53461 tgatgcccaa aaatatctgt actgagtact agacattagg cctagataat aagctctcat
    53521 tgcaattgct tgtatagaaa cataccattt ttctttcaat acagctaaat aatcaggatt
    53581 tgattttttg gtcatttgat caaagtcttt tttaaacgct tcttcaggta gtaaaaattc
    53641 agaggcgaaa atatctgcct catgttcaat tgtcttatat tcttcaggag ataataagtc
    53701 gaattgaata tgacgatgta gaacgagatg tcccagctca tgtgcaagat caaaattcct
    53761 tctaactgct acccccctat ttgtacccag tataataaaa ggtgtctgat ctttactcca
    53821 aaaactatat gcgtctatgc tatcattaat tcgcttttcg tatataacta tacccgcttt
    53881 ttcaagcata aataatagtg cttcgttgct ttcatcttga agaattttag ccctcacaac
    53941 tttagcaatt tcttttatgc tttctttttt atttagtgat tctaaattgc cattcaacaa
    54001 ttcatctaaa ttatttatta aagataaaat aatattatcc ggtatcgtta caaaagaaaa
    54061 taagtagcta gttaaattag ataaatacat tgcttgataa tattgcttat ttaatagttt
    54121 cgtagatact ttataatttt ttgctctaaa agctatacta tgtttatcga cagaatttat
    54181 taggagctct tcgggctgct cgctaataaa gtagctagat ttaacattaa aaatagatgt
    54241 catatcataa attttactaa tttctggcat catatttttt gtttcatatt gccaaattgc
    54301 ttgttcactc acatttattt tttctgataa ttcttttcta cttagagcat taagctttct
    54361 cacgtattct aaattcttgc caataaacat taacttcacc tttcactttc aatcatatcg
    54421 ttaccttcat cgatactgat accaaatgca tgttccacat ctatgagttc taactctcca
    54481 tcgtttttaa gtacttctaa ctcttcttcg tcaatatgat aatcttctct ttctactatt
    54541 actttttcta ttaactctgt caaatcatca accataattg cagaatttgt ttctggattt
    54601 ggtaaccatt gtttgattgc agctaattgc tttgattctt tatcaatacg atatgtaata
    54661 attaaaaaat aagaattaat atctctatta ctgccttctt ttatattaaa taatatacta
    54721 tctgcagtca tttgatgccc aatttcaaaa tcttctccaa cagtaccaaa attaatgtcc
    54781 ctattcttag ccataagtac ctctaggtag tttttacttt ttggattttt atcagcaact
    54841 aaactcttcc ctacgcttac atttttttca tcaaagtaat cttcattttt caatataaac
    54901 atgatattat ttttctcttc atctttatta aatataaact ttaaatactt ccatgatggt
    54961 ccagcatttt ctttaatata cttaacaaaa ttttccaaat gcttagcaac ttgactttca
    55021 atatgattag atttagtaaa ggcataggca tcactaatca ccatacgttt cttgacttca
    55081 tttctctcat taacatagtc cttatatccc gcgataattc ctttaacaat agattctctt
    55141 acttcttgtt taattgtttc caaattaatc acttcataat attaagttat ataaaatata
    55201 agcctcattt tttgtaaaat caacattttt cttaaagtat attgacgttt aag
//
LOCUS       DAPDIM010000009        54834 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000009 DAPDIM010000000
VERSION     DAPDIM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 54834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54834
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.009"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            222..1163
                     /locus_tag="RFE25_000583"
     CDS             222..1163
                     /locus_tag="RFE25_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDU2815683.1"
                     /translation="MTKKVYFNHDGGVDDLVSLFLLLQMENVQLIGVSTIGADCYLEP
                     SLSASVKIINRFSNEDIQVAPSYERGKNPFPKEWRMHAFFMDALPILNEPVKHVASNV
                     SDKEAFEDIIQTLKRQSEKVTLLFTGPLTDLAKALQKDSSIVQYIEKLVWMGGTFLPK
                     GNVEEPEHDGSAEWNAYWDPEAVKIVFDSDIEIDMVALESTNQVPLTLDVRQRWANER
                     QYTGIDFLGVSYAAVPPLTHFITNSTYFLWDVLTTAYIGNKDLVHSIEKKVDVISYGP
                     SQGKTFECKDGRKINVINHVDNNAFFDYITALAKKVN"
     gene            1284..1838
                     /locus_tag="RFE25_000584"
     CDS             1284..1838
                     /locus_tag="RFE25_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDU2815684.1"
                     /translation="MTTKQLVYTALMTAIIAILGMVPVIPLPFSSVPIVLQNIGIFLA
                     GVILGRKYGTLSVIVFLLLVVAGLPLLSGGRGGIGVFAGPSAGFLLLYPVVAFMIGAI
                     RDRFINEINFWILFVGILVFGVIALDVIGTLIMGMIINIPFTKAISISLAYLPGDILK
                     AIVASLIGTALLNHSQFRQIMGLK"
     gene            1915..2685
                     /locus_tag="RFE25_000585"
     CDS             1915..2685
                     /locus_tag="RFE25_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2815685.1"
                     /translation="MASISMSDIYCNGTIFENDDEQLIYLTPSFPQRYTSNTWIYKKT
                     PTQERWLKDLERQHQLHTNQGSNHYAFSFPENEQLDNHWMAMFKDMNFELGIMELYAI
                     ESDALANLPRNSDVEIAVVDESHIDAYLKVAYQFSLPFGKDYADAHEEMVREHYQKDV
                     IKRLVAYLNNEPIGVVDVIESENYIELDGFGVLEQFRHQGIGSTIQSLIGEYAISKNH
                     KPIILVTDGEDTAKDMYAKQGYVYQSFCYQILKEDIGN"
     gene            complement(2857..3654)
                     /gene="fdhD"
                     /locus_tag="RFE25_000586"
     CDS             complement(2857..3654)
                     /gene="fdhD"
                     /locus_tag="RFE25_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDU2815686.1"
                     /translation="MNKDVSLGQPIVRYEDGKLFNTTDQYVTEFPLTIMVNGEEFATV
                     ICSPTNLEELVIGFLASEGAILKRDELKSVLIDDSKGFAHVELNKDLGDRFQYSTKRM
                     IASCCGKSREFYFQNDAAIAKTSMSKITLTPIQIINMMTRLQSASHIYQETGGLHNAA
                     ISDGLTFFVHRQDIGRHNALDKLYGFCIQRHITVRDKVLIFSGRISSEILIKAAKIGV
                     GVILSKSAPTTLAVTLANDLNITAVGFIRNGGFNIYSHPERIIDSEQ"
     gene            3943..4725
                     /gene="modA"
                     /locus_tag="RFE25_000587"
     CDS             3943..4725
                     /gene="modA"
                     /locus_tag="RFE25_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDU2815687.1"
                     /translation="MKMKRFIAIVMALFLVLAGCSNSNDNNESKKDDADNGKKQEIQV
                     AAAASLTDVTKKLASEFKKEHKNADIKFNYGGSGALRKQIESGAPVDVFMSANTKDVD
                     ALKDKNKAHDTYKYAKNSLVLIGDKDSNYTSVKDLKDNDKLALGEVKTVPAGKYAKQY
                     LDNNNLFKEVESKIVYAKDVKQVLNYVEKGNAKQGFVYKTDLYKQNKKIDTVKVIKEV
                     ELKKPITYEAGATSDSKLAKEWMEFLKSDKAKEILKEYHFAA"
     gene            4739..5410
                     /gene="modB"
                     /locus_tag="RFE25_000588"
     CDS             4739..5410
                     /gene="modB"
                     /locus_tag="RFE25_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDU2815688.1"
                     /translation="MPDLTPFWISIRVAVISTIIVTVLGIFISKWLYRRKGSWVKVLE
                     SLLILPIVLPPTVLGFILLIIFSPRGPIGQFFANVLHLPVVFTLTGAVIASVIVSFPL
                     MYQHTVQGFRGIDTKMINTARTMGASETKIFLKLILPLAKRSILAGIMMSFARALGEF
                     GATLMVAGYIPNKTNTLPLEIYFLVEQGRENEAWLWVLVLVAFSIVVISTINLLNKDK
                     YKEVD"
     gene            5411..6016
                     /locus_tag="RFE25_000589"
     CDS             5411..6016
                     /locus_tag="RFE25_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDU2815689.1"
                     /translation="MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMI
                     AGLRKADEAIIEVNGQLLTDTTKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAE
                     PSKHIDQLIQTLNINHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDT
                     TKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG"
     gene            6186..7190
                     /locus_tag="RFE25_000590"
     CDS             6186..7190
                     /locus_tag="RFE25_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HDU2815690.1"
                     /translation="MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGL
                     VRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGC
                     IAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAF
                     IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITY
                     GDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITH
                     DILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
                     "
     gene            7221..7727
                     /locus_tag="RFE25_000591"
     CDS             7221..7727
                     /locus_tag="RFE25_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein MoaB"
                     /protein_id="HDU2815691.1"
                     /translation="MGEHQNVKLNRTVKAAVLTVSDTRDFVTDKGGQCVRQLLQADDV
                     EVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEI
                     EGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELN
                     HLIHELTK"
     gene            complement(7729..8223)
                     /gene="moaC"
                     /locus_tag="RFE25_000592"
     CDS             complement(7729..8223)
                     /gene="moaC"
                     /locus_tag="RFE25_000592"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDU2815692.1"
                     /translation="MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQI
                     SNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNI
                     QTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQR
                     QSGQ"
     gene            8286..9545
                     /locus_tag="RFE25_000593"
     CDS             8286..9545
                     /locus_tag="RFE25_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDU2815693.1"
                     /translation="MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDI
                     VATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVR
                     IMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQV
                     INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALA
                     EKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAE
                     VLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQ
                     IIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPG
                     GSRGFKAGHTVDIILTESDAAEEELLL"
     gene            9542..10027
                     /gene="mobB"
                     /locus_tag="RFE25_000594"
     CDS             9542..10027
                     /gene="mobB"
                     /locus_tag="RFE25_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDU2815694.1"
                     /translation="MILQIVGYKKSGKTTLMRHIVSFLKTHGYTVATIKHHGHAKEDI
                     QLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEG
                     FKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQL
                     T"
     gene            10041..10487
                     /locus_tag="RFE25_000595"
     CDS             10041..10487
                     /locus_tag="RFE25_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein MoaE"
                     /protein_id="HDU2815695.1"
                     /translation="MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKT
                     EYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRK
                     DAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE"
     gene            10493..10726
                     /gene="moaD"
                     /locus_tag="RFE25_000596"
     CDS             10493..10726
                     /gene="moaD"
                     /locus_tag="RFE25_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin converting factor subunit 1"
                     /protein_id="HDU2815696.1"
                     /translation="MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINN
                     KKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG"
     gene            10733..11332
                     /gene="mobA"
                     /locus_tag="RFE25_000597"
     CDS             10733..11332
                     /gene="mobA"
                     /locus_tag="RFE25_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HDU2815697.1"
                     /translation="MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNE
                     IIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMIT
                     GKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFK
                     NIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL"
     gene            11352..12374
                     /gene="moaA"
                     /locus_tag="RFE25_000598"
     CDS             11352..12374
                     /gene="moaA"
                     /locus_tag="RFE25_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDU2815698.1"
                     /translation="MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFL
                     PKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLT
                     TNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGL
                     NVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLT
                     MIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFY
                     GCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKIN
                     MNYIGG"
     gene            complement(12640..12825)
                     /locus_tag="RFE25_000599"
     CDS             complement(12640..12825)
                     /locus_tag="RFE25_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001789125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815699.1"
                     /translation="MFRFISFGQLVVYSTTFIPKKDILQLNDLECDINVKEPLKINYV
                     VIFGSGTEITFSQNLFR"
     gene            12951..13301
                     /gene="sarV"
                     /locus_tag="RFE25_000600"
     CDS             12951..13301
                     /gene="sarV"
                     /locus_tag="RFE25_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarV"
                     /protein_id="HDU2815700.1"
                     /translation="MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEK
                     ISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLL
                     DKITKEIEVLSVTN"
     gene            complement(13403..14614)
                     /locus_tag="RFE25_000601"
     CDS             complement(13403..14614)
                     /locus_tag="RFE25_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2815701.1"
                     /translation="MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQ
                     AFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDG
                     SLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLG
                     MLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETDVINKPRFSIHQFIA
                     KEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRL
                     MDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKV
                     SPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLI
                     HGRHVTRNAMN"
     gene            complement(14607..15047)
                     /locus_tag="RFE25_000602"
     CDS             complement(14607..15047)
                     /locus_tag="RFE25_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix DNA-binding protein"
                     /protein_id="HDU2815702.1"
                     /translation="MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKH
                     QPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEI
                     VCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND"
     gene            15209..15973
                     /locus_tag="RFE25_000603"
     CDS             15209..15973
                     /locus_tag="RFE25_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDU2815703.1"
                     /translation="MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGY
                     INENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKN
                     KLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKK
                     LQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIE
                     DGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV"
     gene            complement(15965..16216)
                     /locus_tag="RFE25_000604"
     CDS             complement(15965..16216)
                     /locus_tag="RFE25_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815704.1"
                     /translation="MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILS
                     IFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY"
     gene            16605..17870
                     /gene="femX"
                     /locus_tag="RFE25_000605"
                     /gene_synonym="fmhB"
     CDS             16605..17870
                     /gene="femX"
                     /locus_tag="RFE25_000605"
                     /gene_synonym="fmhB"
                     /EC_number="2.3.2.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase"
                     /protein_id="HDU2815705.1"
                     /translation="MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIA
                     VGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKA
                     YAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELL
                     NSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYD
                     ALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMIND
                     AQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNH
                     HMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYIL
                     NQPLYQLIEQVKPRLTKAKIKISRKLKRK"
     gene            17987..21154
                     /locus_tag="RFE25_000606"
     CDS             17987..21154
                     /locus_tag="RFE25_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDU2815706.1"
                     /translation="MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQN
                     PVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTD
                     MDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQ
                     LIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGL
                     FQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASP
                     QQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQ
                     VAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLR
                     NIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYR
                     RLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAI
                     AFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWI
                     VIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKY
                     LKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHVDGFKH
                     PGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTY
                     DQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWS
                     EDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTT
                     RQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLA
                     PFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQ
                     GMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISS
                     TLLTLVVVPVIYEILFTLKKRFTKR"
     gene            complement(21338..21655)
                     /gene="mspA"
                     /locus_tag="RFE25_000607"
     CDS             complement(21338..21655)
                     /gene="mspA"
                     /locus_tag="RFE25_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane stabilizing protein MspA"
                     /protein_id="HDU2815707.1"
                     /translation="MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLA
                     LTTMSFPKDNWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTI
                     VLF"
     gene            complement(21900..22064)
                     /locus_tag="RFE25_000608"
     CDS             complement(21900..22064)
                     /locus_tag="RFE25_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815708.1"
                     /translation="MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENE
                     IRNVRAQMQD"
     gene            22197..23105
                     /locus_tag="RFE25_000609"
     CDS             22197..23105
                     /locus_tag="RFE25_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDU2815709.1"
                     /translation="MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSL
                     VIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGL
                     FAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQ
                     SVPLVTYIVMFILNINHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPA
                     TIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTL
                     PFIGMTTNLTIIISIIILYVYQAVFV"
     gene            23512..23643
                     /locus_tag="RFE25_000610"
     CDS             23512..23643
                     /locus_tag="RFE25_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815710.1"
                     /translation="MYGAYLINEYHQDFKSIANFKVLKRMINVMMCYCVLFLEPRIS"
     gene            complement(23760..24623)
                     /locus_tag="RFE25_000611"
     CDS             complement(23760..24623)
                     /locus_tag="RFE25_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter"
                     /protein_id="HDU2815711.1"
                     /translation="MQFLDFLIALSPALFWGSVVLINVFVGGGPYNQIRGTTLGALIV
                     GLGLLITGFAKFNNPTVIIVGLISGALWAFGQANQLKSISLIGVSNTMPVSTGMQLVG
                     TTLFSVIFLGEWSSMTQIIFGLIAMILLVTGVALTSLKAKNERQSDNPEFKKAMGILI
                     VSTVGYVGFVVLGDIFGVGGTDALFFQSVGMAIGGFILSMNHKTSLKSTALNLLPGVI
                     WGIGNLFMFYSQPKVGVATSFSLSQLLVIVSTLGGIFILGERKDRRQMTGIWAGIIII
                     VIAAIILGNLK"
     gene            complement(24804..25691)
                     /locus_tag="RFE25_000612"
     CDS             complement(24804..25691)
                     /locus_tag="RFE25_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2815712.1"
                     /translation="MSIVQLYDITQIKSFIEHSNYESASYLYKLPQQYNEIDVLITDA
                     IESPGVFSIKENDSIKAIILSFAYDKNKFKVIGPFVADNYVLSVDTFETLFKAMTSNQ
                     PDDAVFNFSFEEGIQQYKPLMKVIQASYNFTDYYIEARTRLEEDMHQPNIIPYHKGFY
                     RAFSKLHTTTFKYQAQSPQDIIDSLDDHHHLFLFVSEGLLKGYLYLEIDSQQSIAEIK
                     YFSSHVDYRLKGIAFELLAYALQYAFDNFDIRKVYFKIRNKNNKLIERFNGLGFHINY
                     EYIKFKFESRNVKDQTIPE"
     gene            25757..25840
                     /locus_tag="RFE25_000613"
     CDS             25757..25840
                     /locus_tag="RFE25_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815713.1"
                     /translation="MILTCYNTFNTIEFKSKISGIDEARSK"
     gene            25866..28001
                     /locus_tag="RFE25_000614"
     CDS             25866..28001
                     /locus_tag="RFE25_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDU2815714.1"
                     /translation="MKSLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHL
                     VTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIA
                     TDAGREGELVARLILDKVGNKKPIRRLWISSVTKKAIQQGFKNLKDGRQYNDLYYAAL
                     ARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYFTLSL
                     TVKGFDFQLESNQRYTNKETLEQMVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQ
                     DMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQATMATTYK
                     DQARPLMSKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLE
                     ALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKI
                     SKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADI
                     IDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAK
                     TFINEMKDFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPS
                     CKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKV
                     SRKEMKKYMNKNEGLDNNPFKDALKNLNL"
     gene            28114..29448
                     /locus_tag="RFE25_000615"
     CDS             28114..29448
                     /locus_tag="RFE25_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDU2815715.1"
                     /translation="MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGV
                     KGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMG
                     IPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
                     IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGL
                     IQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAV
                     ATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASI
                     VTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITII
                     MMPLSYSIATGIACGFIFYPITMLISKKQKEVHPIMYVLMVLFILYFIFVHG"
     gene            complement(29639..30028)
                     /locus_tag="RFE25_000616"
     CDS             complement(29639..30028)
                     /locus_tag="RFE25_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815716.1"
                     /translation="MKNGPKLSLALIGIFLILCEFFYGIPFLGATFILSFGWQPLLFN
                     ALLYLILTIILLVNRQNAIRPIAIIPIFGIVGSFLAIIPFLGILIHWILFFLMILFVL
                     VVLSAPTYIPNKNARVIYTQYKDGHRE"
     gene            30385..30693
                     /gene="rpsJ"
                     /locus_tag="RFE25_000617"
     CDS             30385..30693
                     /gene="rpsJ"
                     /locus_tag="RFE25_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDU2815717.1"
                     /translation="MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPT
                     EKSVYTIIRAVHKYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
                     "
     gene            30721..31383
                     /gene="rplC"
                     /locus_tag="RFE25_000618"
     CDS             30721..31383
                     /gene="rplC"
                     /locus_tag="RFE25_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDU2815718.1"
                     /translation="MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVD
                     GYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVG
                     QEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDA
                     SRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKG
                     NK"
     gene            31410..32033
                     /gene="rplD"
                     /locus_tag="RFE25_000619"
     CDS             31410..32033
                     /gene="rplD"
                     /locus_tag="RFE25_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDU2815719.1"
                     /translation="MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASL
                     RQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMP
                     KKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENED
                     VNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG"
     gene            32033..32308
                     /gene="rplW"
                     /locus_tag="RFE25_000620"
     CDS             32033..32308
                     /gene="rplW"
                     /locus_tag="RFE25_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002506966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDU2815720.1"
                     /translation="MEARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEE
                     IFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSIDLFN"
     gene            32341..33174
                     /gene="rplB"
                     /locus_tag="RFE25_000621"
     CDS             32341..33174
                     /gene="rplB"
                     /locus_tag="RFE25_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDU2815721.1"
                     /translation="MAIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRN
                     NQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKR
                     YIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGA
                     SAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKK
                     K"
     gene            33241..33519
                     /gene="rpsS"
                     /locus_tag="RFE25_000622"
     CDS             33241..33519
                     /gene="rpsS"
                     /locus_tag="RFE25_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDU2815722.1"
                     /translation="MARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNF
                     IGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHVADDKKTRR"
     gene            33548..33901
                     /gene="rplV"
                     /locus_tag="RFE25_000623"
     CDS             33548..33901
                     /gene="rplV"
                     /locus_tag="RFE25_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDU2815723.1"
                     /translation="MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASS
                     PVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSH
                     ITIVVSDGKEEAKEA"
     gene            33925..34578
                     /gene="rpsC"
                     /locus_tag="RFE25_000624"
     CDS             33925..34578
                     /gene="rpsC"
                     /locus_tag="RFE25_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDU2815724.1"
                     /translation="MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDN
                     ELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINV
                     IEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQVSGRLGGAD
                     IARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK"
     gene            34581..35015
                     /gene="rplP"
                     /locus_tag="RFE25_000625"
     CDS             34581..35015
                     /gene="rplP"
                     /locus_tag="RFE25_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDU2815725.1"
                     /translation="MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITS
                     RQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRI
                     LFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES"
     gene            35005..35214
                     /gene="rpmC"
                     /locus_tag="RFE25_000626"
     CDS             35005..35214
                     /gene="rpmC"
                     /locus_tag="RFE25_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002509269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDU2815726.1"
                     /translation="MKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIR
                     TVRKTIARLKTVAREREIEQSKANQ"
     gene            35238..35501
                     /gene="rpsQ"
                     /locus_tag="RFE25_000627"
     CDS             35238..35501
                     /gene="rpsQ"
                     /locus_tag="RFE25_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDU2815727.1"
                     /translation="MSERNDRKVYVGKVVSDKMDKTITVLVETYKTHKLYGKRVKYSK
                     KYKTHDENNSAKLGDIVKIQETRPLSATKRFRLVEIVEESVII"
     gene            35533..35901
                     /gene="rplN"
                     /locus_tag="RFE25_000628"
     CDS             35533..35901
                     /gene="rplN"
                     /locus_tag="RFE25_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDU2815728.1"
                     /translation="MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVK
                     NATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPV
                     ARELREGNFMKIVSLAPEVL"
     gene            35937..36254
                     /gene="rplX"
                     /locus_tag="RFE25_000629"
     CDS             35937..36254
                     /gene="rplX"
                     /locus_tag="RFE25_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDU2815729.1"
                     /translation="MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKH
                     QKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIK
                     SNN"
     gene            36281..36820
                     /gene="rplE"
                     /locus_tag="RFE25_000630"
     CDS             36281..36820
                     /gene="rplE"
                     /locus_tag="RFE25_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDU2815730.1"
                     /translation="MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAV
                     QNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDK
                     LISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTA
                     NTDEEARELLANFGMPFRK"
     gene            36843..37028
                     /locus_tag="RFE25_000631"
     CDS             36843..37028
                     /locus_tag="RFE25_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDU2815731.1"
                     /translation="MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICF
                     RELAYKGQIPGVRKASW"
     gene            37060..37458
                     /gene="rpsH"
                     /locus_tag="RFE25_000632"
     CDS             37060..37458
                     /gene="rpsH"
                     /locus_tag="RFE25_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDU2815732.1"
                     /translation="MTMTDPIADMLTRVRNANMVRHEKLELPASNIKKEIAEILKSEG
                     FIKNVEYVEDDKQGVLRLFLKYGQNDERVITGLKRISKPGLRVYAKASEMPKVLNGLG
                     IALVSTSEGVITDKEARKRNVGGEIIAYVW"
     gene            37483..38019
                     /gene="rplF"
                     /locus_tag="RFE25_000633"
     CDS             37483..38019
                     /gene="rplF"
                     /locus_tag="RFE25_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDU2815733.1"
                     /translation="MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFK
                     QEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKD
                     LILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGK
                     GIRYQGEYVRRKEGKTGK"
     gene            38050..38409
                     /gene="rplR"
                     /locus_tag="RFE25_000634"
     CDS             38050..38409
                     /gene="rplR"
                     /locus_tag="RFE25_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDU2815734.1"
                     /translation="MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQI
                     IDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYH
                     GRVKALAEAARESGLEF"
     gene            38430..38930
                     /gene="rpsE"
                     /locus_tag="RFE25_000635"
     CDS             38430..38930
                     /gene="rpsE"
                     /locus_tag="RFE25_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016426364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDU2815735.1"
                     /translation="MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNG
                     RVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGRYGSGSVFMKPAAPG
                     TGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATIDGLQNLKNAEDVAKLRGKT
                     VEELYN"
     gene            38947..39126
                     /gene="rpmD"
                     /locus_tag="RFE25_000636"
     CDS             38947..39126
                     /gene="rpmD"
                     /locus_tag="RFE25_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDU2815736.1"
                     /translation="MAKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIR
                     GQINKVKHLVTVEEK"
     gene            39143..39583
                     /gene="rplO"
                     /locus_tag="RFE25_000637"
     CDS             39143..39583
                     /gene="rplO"
                     /locus_tag="RFE25_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDU2815737.1"
                     /translation="MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGG
                     GVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVV
                     KNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI"
     gene            39583..40875
                     /gene="secY"
                     /locus_tag="RFE25_000638"
     CDS             39583..40875
                     /gene="secY"
                     /locus_tag="RFE25_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDU2815738.1"
                     /translation="MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAAF
                     DNPQGSQGATELLNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQ
                     GEVGRRKLNNVTRYLAISLAFIQSIGMAFQFNNYLKGALIINQSIMSYLLIALVLTAG
                     TAFLIWLGDQITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVL
                     GLLVSLILLTVGAIYVLEAVRKIPIQYAKKQTAQRLGSQATYLPLKVNSAGVIPVIFA
                     MAFFLLPRTLTLFYPDKEWAQNIANAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEK
                     MADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQ
                     SIQIGGTSLLIVIGVAIETMKSLEAQVSQKEYKGFGGR"
     gene            40892..41539
                     /locus_tag="RFE25_000639"
     CDS             40892..41539
                     /locus_tag="RFE25_000639"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDU2815739.1"
                     /translation="MNIILMGLPGAGKGTQASEIVKKFPIPHISTGDMFRKAIKEETE
                     LGKEAKSYMDRGELVPDEVTVGIVKERISEDDAKKGFLLDGFPRTIEQAEALNNIMSE
                     LDRNIDAVINIEVPEEELMNRLTGRRICESCGTTYHLVFNPPKVEGICDIDGGKLYQR
                     EDDNPETVANRLSVNIKQSKPILDFYDQKGVLKNIDGSKDISDVTKDVIDILDHL"
     gene            41732..41950
                     /gene="infA"
                     /locus_tag="RFE25_000640"
     CDS             41732..41950
                     /gene="infA"
                     /locus_tag="RFE25_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017185218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDU2815740.1"
                     /translation="MAKQDVIELEGTVLDTLPNAMFKVELENGHEILAHVSGKIRMNY
                     IRILPGDKVTVEMSPYDLTRGRITYRYK"
     gene            41982..42095
                     /gene="rpmJ"
                     /locus_tag="RFE25_000641"
     CDS             41982..42095
                     /gene="rpmJ"
                     /locus_tag="RFE25_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDU2815741.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG"
     gene            42118..42483
                     /gene="rpsM"
                     /locus_tag="RFE25_000642"
     CDS             42118..42483
                     /gene="rpsM"
                     /locus_tag="RFE25_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDU2815742.1"
                     /translation="MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTR
                     VKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKT
                     KNNARTRKGPVKTVANKKK"
     gene            42507..42896
                     /gene="rpsK"
                     /locus_tag="RFE25_000643"
     CDS             42507..42896
                     /gene="rpsK"
                     /locus_tag="RFE25_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016998822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDU2815743.1"
                     /translation="MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSW
                     SSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQS
                     AGLEVTAIRDVTPVPHNGCRPPKRRRV"
     gene            42971..43915
                     /locus_tag="RFE25_000644"
     CDS             42971..43915
                     /locus_tag="RFE25_000644"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDU2815744.1"
                     /translation="MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRIL
                     LSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVR
                     DEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLP
                     IGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMT
                     EHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQE
                     LADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED"
     gene            43932..44300
                     /gene="rplQ"
                     /locus_tag="RFE25_000645"
     CDS             43932..44300
                     /gene="rplQ"
                     /locus_tag="RFE25_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002450507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDU2815745.1"
                     /translation="MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVV
                     EKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTR
                     ILKQGPRRGDGAESVIIELV"
     gene            44838..45647
                     /locus_tag="RFE25_000646"
     CDS             44838..45647
                     /locus_tag="RFE25_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDU2815746.1"
                     /translation="MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHN
                     GSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVK
                     YDVAFGLENHAVPHDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIASVLALN
                     PSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKG
                     TVYKEGTATEIFDHAEELTRIGLDLPFPIKINQMLGHQTSFLTYEGLVDQL"
     gene            45644..46504
                     /locus_tag="RFE25_000647"
     CDS             45644..46504
                     /locus_tag="RFE25_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDU2815747.1"
                     /translation="MTIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGS
                     GKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDT
                     VEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSIL
                     AMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKAIILISHDMNEVARYADEVIV
                     MKEGSIVSQTSPKELFKDKKKLADWHIGLPEIVQLQYDFEQKYQTKLKDIALTEEAFV
                     SLYKEWQHEK"
     gene            46494..47300
                     /locus_tag="RFE25_000648"
     CDS             46494..47300
                     /locus_tag="RFE25_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDU2815748.1"
                     /translation="MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLT
                     YLWVFALILFIMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITI
                     ETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMI
                     MSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEE
                     LAVAMEVRGYDANVKRTSYRQLKWQLRDTISLTMIIPIAIILFVLKYSGV"
     gene            47305..48108
                     /gene="truA"
                     /locus_tag="RFE25_000649"
     CDS             47305..48108
                     /gene="truA"
                     /locus_tag="RFE25_000649"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDU2815749.1"
                     /translation="MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRI
                     HPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRY
                     DCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNRAAQQFIGTHDFTGFCSQKT
                     EVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEISDVPKL
                     LESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND"
     gene            48348..48785
                     /gene="rplM"
                     /locus_tag="RFE25_000650"
     CDS             48348..48785
                     /gene="rplM"
                     /locus_tag="RFE25_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019468667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDU2815750.1"
                     /translation="MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVT
                     YTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLI
                     ENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG"
     gene            48799..49197
                     /gene="rpsI"
                     /locus_tag="RFE25_000651"
     CDS             48799..49197
                     /gene="rpsI"
                     /locus_tag="RFE25_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDU2815751.1"
                     /translation="MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFE
                     SLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKR
                     AGLLTRDPRMKERKKPGLKAARRSPQFSKR"
     gene            complement(49375..50322)
                     /locus_tag="RFE25_000652"
     CDS             complement(49375..50322)
                     /locus_tag="RFE25_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016170730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815752.1"
                     /translation="MKKSIYILPLAYIVIESPLQIGNVILTPSLKVIESGHFHTDFSL
                     ISMFNKKEFLSILSTSQLKEDALVIFKDDFFEPTTVDQNYYFINKLSQKADRTLDIIR
                     INENNFGVPEQLPGIPGITSNGWQVAEQLTDHKLRTINGKVMFMIREGIGLYPIDLSS
                     NIYEDKLYNCLYVTSNEINLLFREAIHRVSESMYMNNLNTSFVYLLSTLEMLSSREYL
                     NFKKTKSKILPFISYSKHQYHKCSEYLRNISENLRTEIIHNGKSIFDLYDNYEDVYKL
                     LNWIKLIIIEYISNIVKKNIQTFDDLEKERKKIINSLGI"
     gene            complement(50604..50789)
                     /locus_tag="RFE25_000653"
     CDS             complement(50604..50789)
                     /locus_tag="RFE25_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDU2815753.1"
                     /translation="MKNKHVLQPLKKCEYQRWIDIGIQTINKLLQWKEEQNLQNEEYG
                     FSVSSDKEQHIFSTYHT"
     gene            51251..51493
                     /locus_tag="RFE25_000654"
     CDS             51251..51493
                     /locus_tag="RFE25_000654"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDU2815754.1"
                     /translation="MKGYQQMSPKGTTRIETKTGHQAQFDWKEGINFKTNDNQIVSLN
                     IGVLLLSYSRFVIMKVTMNKSSDVLFNLFTQAFELM"
     gene            51977..52695
                     /locus_tag="RFE25_000655"
                     /pseudo
     CDS             51977..52695
                     /locus_tag="RFE25_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066123.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            53440..53688
                     /locus_tag="RFE25_000656"
     CDS             53440..53688
                     /locus_tag="RFE25_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001797059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDU2815755.1"
                     /translation="MRAFTEANKKSKYQEQTNNARKSEASNCPICNTDLQYDHQTHIW
                     NYKDMVGDHIIPWSKGGKTERGNLQMLYKHHNSLKSNY"
     gene            53768..54415
                     /locus_tag="RFE25_000657"
     CDS             53768..54415
                     /locus_tag="RFE25_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815756.1"
                     /translation="MKQNVEFNQAVIKFNKRNKINKSSNDEYIKKFRNKFGKFLSQSF
                     LNSNNVIKQEIIKIIKDEYYYYDQENTKKYLIKFCQDLIEHIKEHRNQINDCHFTNIL
                     NKDAEKTNSSSILTSLFLTANNIPNNLSSNFSKAVEYYFAKNKEIYGDGYEKYLDEYF
                     RNVLGEKSYLILIDDFSGTGKSISDFIDAIKKYILTLKIEIIIFCIHITEDAEKK"
     gene            54415..>54834
                     /locus_tag="RFE25_000658"
     CDS             54415..>54834
                     /locus_tag="RFE25_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815757.1"
                     /translation="MDTSIKNGIEIKIAFVQKTEKYFINNKELEKKFYEFEKDIVNPG
                     KYYNLGYKNTQALVSNFRNTPNNTLSLFWHENDQWKPLFKRKAKNDFSNKWKEKVHII
                     RWFLAYKKVPKILVDKIIAIMYVKNHADMKSKFLEIEI"
BASE COUNT        19870 a         8075 c        10234 g        16655 t
ORIGIN      
        1 atacctgaga aaatagctca atgtatctct ttattgataa gttatatcat aattatatta
       61 gtgcatactt tatggaaggg atatcaggga atggctatca ataaaagaag aggtttaaaa
      121 ggattacaac agaatgttat gattttgtag aaagatatat aacaacgttt tataaaaaca
      181 taatattgtt aatggacaat gaaatgtaag ggggatttcg agtgactaag aaagtttatt
      241 ttaaccatga tggtggtgta gatgatttag tatctctatt tttattatta caaatggaaa
      301 acgttcaatt gataggggtc agtacaattg gtgctgattg ttatttagag ccatctttga
      361 gcgcatcagt aaaaattatt aatcgttttt caaatgaaga tattcaagtt gcgccatcat
      421 atgaacgagg aaaaaatcca tttcctaaag aatggcgtat gcatgccttt tttatggacg
      481 cattgccaat tttaaatgag ccagtcaaac atgttgcttc aaatgtgagc gacaaagaag
      541 cctttgaaga cattattcaa actttaaaga gacaatcaga aaaagtaaca ttattattta
      601 caggcccgct tacagattta gcaaaagcac tacaaaaaga ttcatctatc gttcagtata
      661 tagaaaaatt agtttggatg ggtggcacct ttttaccaaa aggaaatgtt gaagaacctg
      721 agcatgatgg ttctgcagaa tggaatgcat attgggatcc agaagcggtt aaaattgttt
      781 ttgatagcga tatagagatt gatatggttg ctttagaaag tacgaatcaa gtgccgctaa
      841 cgttagatgt tagacaaaga tgggcgaatg aacgccaata tacgggcatt gattttttag
      901 gagtaagtta tgcagcggta ccaccattaa cacactttat aacaaattct acttactttt
      961 tatgggatgt tttaacgact gcttatattg gtaacaagga cttggttcat tcaattgaga
     1021 aaaaagtcga tgtaataagt tatggaccaa gtcaaggtaa gacatttgag tgtaaagatg
     1081 ggcgcaaaat taatgtcata aatcatgtag ataacaacgc attttttgat tatataactg
     1141 cacttgctaa aaaagtaaat taacagctgt gtagaataat taaggtttta atttatatag
     1201 aacaacttat tgtaaacttt tcatttctta aagtttacaa tggtgctata ataatggtca
     1261 tgaaatacga aaggaagtaa aaaatgacaa caaaacagtt agtatataca gctttaatga
     1321 cagcgattat cgctatttta ggaatggtac cggtaattcc actaccattt tcttcagtac
     1381 caattgtact tcaaaacatt ggtattttct tagcaggtgt gattttagga cgtaaatatg
     1441 gcacattaag tgttatcgtc tttttattat tagtagttgc tggcttgcca ttgttatcag
     1501 gtggtcgcgg tggcatcggt gtattcgcag gtccttcagc agggttttta ctattatatc
     1561 cagttgtagc attcatgatt ggtgcgattc gtgatagatt catcaatgaa attaatttct
     1621 ggattttatt cgttggtatt ttagtttttg gtgttatagc attagatgtt attggtacat
     1681 tgattatggg catgattatt aacataccat ttacgaaagc tatttcaatt tcattagctt
     1741 atttgcctgg tgatatatta aaagcaattg tagcaagttt gattggtaca gctttactta
     1801 atcactcgca gtttcgtcaa attatgggat taaaataatc atatttaagt taagataata
     1861 aagtaattga ataagttgct ttgaaattta taaaagtgaa aggagtaggt gtcaatggct
     1921 agtataagta tgtcagatat atattgtaac ggcactatat ttgaaaatga cgacgagcag
     1981 ttaatttatt taacgccttc ttttccacaa cgatacacaa gcaacacatg gatatataaa
     2041 aagacgccta cccaagagcg atggctgaaa gacttagaac gtcaacatca attacataca
     2101 aatcaaggtt caaatcatta tgcgtttagt ttcccggaaa atgaacaact tgataatcat
     2161 tggatggcta tgtttaaaga tatgaatttt gaactaggta ttatggaatt gtatgccata
     2221 gaaagtgatg cgcttgctaa tttgccgcgt aactctgacg ttgaaattgc cgtcgttgac
     2281 gagtcgcata tagatgccta tttaaaagtt gcatatcagt ttagtctgcc atttggaaaa
     2341 gactatgcag atgcacatga agaaatggta agggaacatt atcaaaaaga tgtgattaaa
     2401 cgcttagtag cttatttaaa taatgaacct attggcgttg tagatgtcat tgaaagtgaa
     2461 aattacattg aattagatgg atttggtgta ttagaacaat ttcgacacca aggaattgga
     2521 tctacaattc aatcgttgat aggtgaatac gccatatcaa aaaatcacaa accaatcata
     2581 ttagttacag atggtgaaga tacagcaaaa gatatgtatg caaagcaagg ttatgtctat
     2641 caatcgtttt gttatcaaat attaaaagaa gatattggaa attaacgatt gatgataggt
     2701 ttgtattaga ataaaaaagc agtaagctgg tttcgagtag aaatcaactt actgcttttt
     2761 aaattgtttt gagctactta tacttataaa aatagtgcgt ttaaattgtt gattcatgta
     2821 gaatatcgtt cattatgaca cactataatg aatatgttat tgttcagagt cgatgatacg
     2881 ttctggatga ctatatatat taaagccacc atttcgaata aaacctactg ccgtaatatt
     2941 taggtcatta gctaaggtta cagcaagcgt tgtcggagct gatttagata aaatgacgcc
     3001 aacaccgatt ttcgcggctt taattaaaat ttctgatgaa atacgtccac taaaaattaa
     3061 tactttatct cggacagtaa tatgtcgctg gatacaaaat ccatataatt tatctagagc
     3121 gttatgtcta ccaatgtctt gtcgatgtac aaaaaatgtc aaaccatcgc ttatagcagc
     3181 attatgtaag ccacctgttt cttggtaaat atgacttgca ctttgtaatc gagtcatcat
     3241 gttaataatt tgtattggag ttaaagtgat tttagacata gaagttttag cgatagcagc
     3301 atcattttga aaataaaact cacgactctt tccacaacaa gatgcaatca ttcgttttgt
     3361 ggaatattga aagcgatcgc ctaaatcttt attaagttca acatgggcaa aacctttact
     3421 atcatcaatc agcacagatt ttaattcatc tcgctttaaa atggcacctt ccgaagccag
     3481 aaatccaatg actaactcct caaggtttgt tggactgcat ataacagtcg caaattcttc
     3541 accattcacc ataattgtaa gtggaaattc tgtcacatat tgatctgttg tattgaataa
     3601 ttttccatct tcatatctaa caattggttg acctaaagat acatctttgt tcattatcta
     3661 acccctttaa ttagcttaaa ctttatttta aagcaatttg cttaaaattt taacatattt
     3721 gcttaagttt gaaatttgat ttataaaatt aatagcgagc aatctgtttg atttaaattg
     3781 aattcgagag tatacatact aggggatcaa ttaataaata tcaatcttat gcaaatttga
     3841 caattgtttg aatcaatata taaacaggca acggttcttt tcaaatataa tagtaagtgt
     3901 ataatgaaaa tgtaaatatt attaaaaatg ggggttcact caatgaaaat gaaacgtttt
     3961 atagctattg taatggcatt atttttagta ttagctggtt gctctaattc taacgataat
     4021 aatgaaagta aaaaagatga cgcagacaat ggtaagaaac aagagattca agttgcagcg
     4081 gcagcaagtt taacagatgt aaccaagaaa ttagcttcag aatttaaaaa agagcataaa
     4141 aatgctgata ttaaatttaa ctatggtgga tcaggggcat taagaaaaca aattgaatca
     4201 ggcgcacctg ttgacgtatt tatgtctgca aatactaaag atgtagatgc attaaaagac
     4261 aagaataaag cgcatgatac atataaatat gcgaaaaata gtctagtatt aattggtgat
     4321 aaagattcaa attacacttc agtaaaagac ttaaaagaca atgataaatt agcattaggt
     4381 gaagtgaaaa ctgtaccagc aggaaaatat gcgaaacagt atttagataa caataactta
     4441 tttaaagaag tcgaaagtaa aatcgtttat gctaaagatg taaaacaagt attaaattat
     4501 gttgaaaagg gtaatgcgaa acaaggtttt gtgtataaaa ctgacttata taaacaaaac
     4561 aaaaaaattg atactgtaaa agtaattaaa gaagtagaac ttaagaaacc aatcacatac
     4621 gaagctggtg ctacatcaga tagtaaatta gcaaaagagt ggatggaatt cttaaaatca
     4681 gataaagcta aagaaatatt aaaagaatac cactttgcag cataaggagt tgtaatccat
     4741 gcctgactta acaccttttt ggatatcaat acgagttgct gtaatcagta cgattattgt
     4801 aacggtttta ggtattttta tatctaaatg gttgtatcgt cgtaagggtt cgtgggttaa
     4861 agtattggaa agtttattga tattacctat tgttttgccg ccaacggtat taggttttat
     4921 tctattaatc atcttctcgc caagaggacc aatcggtcaa ttctttgcga atgtactaca
     4981 tttacctgta gtgttcactt tgacaggtgc tgtgatagca tctgtcattg ttagttttcc
     5041 actaatgtat caacatactg tgcaaggctt cagaggtata gacacgaaaa tgattaatac
     5101 agctagaacg atgggagcaa gtgaaacgaa aattttcctc aaattaattt taccattagc
     5161 taaacgctct attttagcag gtataatgat gagttttgct cgtgcattag gtgagtttgg
     5221 tgctacatta atggttgcag gatatattcc aaataaaacg aatacactac ctttagaaat
     5281 atacttctta gtggaacaag gtagagaaaa tgaagcgtgg ttatgggtat tagtgctagt
     5341 cgcattctct attgtggtta tatctacaat taatttattg aataaagata aatataagga
     5401 ggtcgactag atgcttaaaa tcaatgtgaa atatcaatta aagaacactt taattcgcat
     5461 caatatagat gatactgaac caaaaattta tgcagttcgt ggtccatctg gcattggtaa
     5521 aactactgtt ttaaatatga ttgccggatt acgtaaagca gatgaagcta ttatcgaagt
     5581 gaatgggcaa ttgcttactg atacgacaaa aaacgtgaat gttaaaattc aacaacgacg
     5641 tattggatat ctgtttcaag actaccaatt gtttcctaat atgacggttt ataaaaatat
     5701 tacttttatg gctgaaccat ctaaacacat cgatcaatta attcaaactt taaacattaa
     5761 tcatttgatg aaacaatatc ctatgacatt gtcaggtgga gaggcacaac gtgtagcact
     5821 tgcacgtgca cttagcacga aaccagattt aattttatta gatgaacctt tttctagttt
     5881 ggatgatact acaaaagatg agagtattac attagttaaa cgtattttca acgaatggca
     5941 aataccaatc atatttgtga cacattcaaa ctatgaagca gaacaaatgg ctcatgaaat
     6001 tattacaatt gggtaatcat ttatttgcca ttaaagagtt tagaacgtat ttaaaattgt
     6061 agaagtgaat gcttctatca gcattttaat gatgttttaa actctttttt aggggcagtt
     6121 tttttgagag acattgacgc gcgtcatata atgaaagtaa tgataaaaag aaaggataac
     6181 ttaatgtgag tcaagaacgt tattcaaggc aaattttatt taaacaaata ggtgaaatag
     6241 gtcaaagcaa aataaatcaa aaatgtgcgt tgattattgg tatgggcgca ttaggtacac
     6301 atgtggccga aggacttgtt agagcaggca ttgctaaact aatcattgtt gatagagatt
     6361 atattgaatt tagtaattta caaagacaaa cattgtttac tgaagaagat gctttgaaaa
     6421 tgatgcctaa agtggttgca gctaaaaagc atttgctagc gttacgtagt gatgttgata
     6481 ttgatggttg tattgcccat gtggattatt attttttgga aacacatgga caggacgttg
     6541 acgttattat tgatgcaacc gataactttg aaacacgaca actgattaat gattttgcat
     6601 ataaacatcg tataccttgg atttatggtg gtgttgtaca gagtacatat acagaagctg
     6661 catttatacc tggtaaaaca ccttgcttta actgtttggt accacaattg ccagcattaa
     6721 atttaacatg tgatacagta ggggtcattc aacctgccgt gacgatggca acaagtttac
     6781 aattaagaga tgcgatgaaa gtattaacgg aacaaccaat tgacacaaaa ataacttatg
     6841 gcgatatttg ggaaggtagt cattattcat ttggtttcag taaaatgcaa cgttcagact
     6901 gtacaacttg tggagatgta ccaagttatc cgtatttaaa caagaatgaa caacgttatg
     6961 caacattgtg tggtagagac actgtacagt atgaaaatgc atcaattaca cacgacattc
     7021 ttgttcaatt tttaaaacaa catcaactaa attatcgcag taattcgtat atggttatgt
     7081 ttgaatttaa aggacaccgc attgttgctt ttaaaggtgg aaggttttta atacatggca
     7141 tgacacgcac atcagatgcc acacatctaa tgaatttatt gtttggataa aaaaagataa
     7201 gacaaaagga gtgtaatatt atgggcgaac atcaaaacgt taaattgaat cgtacagtta
     7261 aagcagccgt actaacggta tcagatacta gagactttgt tacagataaa ggtggtcaat
     7321 gcgtgcgcca actattacaa gcagatgacg ttgaagtgag tgacgcacat tatacaattg
     7381 tgaaagatga aaaagtagcc atcacgacgc aggtgaagaa gtggttagaa gaagatattg
     7441 atgtcatcat tacgactggt ggaacaggta ttgcacaacg tgatgtgacg attgaagcag
     7501 taaaaccact tttaactaaa gagatagaag gctttgggga attgtttaga tatttgagtt
     7561 atgttgaaga tgttggcacg cgtgcattat tgtctcgtgc tgtagcaggt acagttaata
     7621 ataaattgat attttcgatt ccaggatcaa caggcgcagt taaattagca ttagaaaagc
     7681 tcattaaacc agaattaaat catctgattc atgagcttac aaaataattt attgacctga
     7741 ttggcgttga aaatctccag atttaccgcc agacttgctt tcaaggtagg tttcgccaat
     7801 aatcatacct ttatcaactg ctttcgtcat gtcgtaaatg gttaaagccg ttgctgatgc
     7861 agcggttaaa gcttccattt caacaccggt tttgccagtt gtagagacag ttgtttgaat
     7921 gtttaaagta taaaggggtg catttgtttc atcccagctg aagtgaacat ctatgccagt
     7981 caatggtaat ggatggcaca tcggaataat tgttgatgta tttttggcag ccataatacc
     8041 agcgatttga gcagtgttca atacattgcc tttggtattg gtgttattag aaatctgctt
     8101 aaaaatagtt tcattcacag taatgcttga atgagcgaca gcagttcttt ttgtaatttg
     8161 tttgtctgat acatcgacca ttttggcgtg gccttgttga ttaatatgag taaactcagt
     8221 cattttaccc ctcctagtgc atctagtata tcatgaaaaa ataaaagttt tggagatgat
     8281 ttttaatggt agtagaaaaa agaaacccaa tcccagttaa agaagcaatt caacgtatcg
     8341 ttaatcagca gagttcaatg ccggcaatta cggtagcact tgaaaaaagt ctaaatcata
     8401 tcttagcaga agatattgta gctacttatg atataccaag gtttgataaa tcaccttatg
     8461 atggttttgc aattcgcagt gttgattcac aaggggcaag tggtcagaat cgcattgagt
     8521 ttaaagtgat tgatcatatt ggtgcaggtt cagtttctga taaattagtt ggggatcacg
     8581 aagcggtgcg tattatgact ggagcacaaa taccaaatgg cgcagatgct gttgttatgt
     8641 ttgaacaaac gattgaacta gaagatacat ttacaattcg taaaccattt tcaaaaaatg
     8701 aaaatatatc tttaaaaggt gaagaaacaa agacaggcga tgttgttcta aaaaaaggac
     8761 aagtaattaa cccaggggct atcgcggtcc ttgcaacata tggctatgca gaggttaaag
     8821 ttattaagca accgagtgtc gctgttattg caacaggaag cgaattatta gatgttaatg
     8881 atgtattaga agatggaaaa attcgtaact ctaatggccc aatgattcgt gccttagcag
     8941 aaaaattagg tcttgaagtt ggtatttaca aaacacaaaa agatgattta gatagtggca
     9001 tccaagtcgt taaagaagct atggaaaaac acgatatcgt tattacaacg ggtggagttt
     9061 ctgttggaga ctttgactat ttacctgaga tttataaggc tgtaaaggcg gaagtgttat
     9121 ttaataaagt agcaatgcgt cctggtagcg taacaacggt tgcatttgca gatggaaagt
     9181 atttgtttgg attatctgga aatccatcag cttgttttac aggatttgaa ctatttgtga
     9241 aaccagctgt taaacatatg tgtggcgcac tagaagtctt cccgcaaata attaaagcaa
     9301 cattaatgga agattttacc aaggcaaacc cattcacacg atttatacgt gctaaagcaa
     9361 cgttaacaag tgctggagct actgtagtac cttcaggatt caataaatca ggtgcggttg
     9421 tagcgattgc acatgctaac tgtatggtca tgttaccagg agggtcacgt ggttttaaag
     9481 cggggcatac agtagatatt atattgactg aatctgacgc tgctgaagag gaacttcttt
     9541 tatgatttta caaattgtag gttacaaaaa gtctggtaag acaacattga tgaggcatat
     9601 tgtctctttc ttaaagacac atggttatac agttgctact attaaacatc atgggcatgc
     9661 taaggaagat attcaattac aggattcaga cgtcgatcac atgaagcatt ttgaagcggg
     9721 ggcagatcaa agtattgtac aaggttttca atatcagcaa actgtaacac gtgtagataa
     9781 tcaaaatctt actcaaatta ttgagaaatc tgttacaatt gacaccaata tcgtattagt
     9841 tgaaggcttt aaaaatgctg attttgaaaa agtcgtagtc tatcgagatg aagaagagtt
     9901 gcaagtatta caacaattgt cgaatgtttg ttatagcatt aatgtaaggg agcatgaaga
     9961 ttttacagca tttgagcaat ggttattaaa taaaattaaa aatgattgtg atacacaatt
    10021 aacatagagg attgaaatga atgaaacaat ttgaaatcgt gatagaaccg atacaaacag
    10081 aacaatatcg tgaattcact ataaatgaat atcaaggtgc agtagttgtt tttaccggtc
    10141 atgttcgcga atggactaaa ggcgtcaaaa cggaatattt agaatatgaa gcgtatattc
    10201 caatggctga aaagaaattg gcacaaattg gagatgaaat aaatgaaaaa tggcctggaa
    10261 cgataacgag tattgttcat agaatagggc cattacaaat ttcagatatc gctgtattaa
    10321 ttgcagtttc ttcaccgcat cgtaaagatg cctatcgagc aaatgaatat gcaattgagc
    10381 gtataaaaga aattgttccg atttggaaaa aagaaatttg ggaagatggt tcaaaatggc
    10441 aagggcatca aaaagggaat tatgaagaag cgaagaggga ggaataagag agatgaaggt
    10501 actttacttc gcagaaatta aagatatatt acaaaaagca caggaagata ttgtgcttga
    10561 acaagcattg actgtacaac aatttgaaga tttattgttt gaacgttatc cgcaaatcaa
    10621 taataaaaag tttcaagttg ctgtaaatga ggaatttgta caaaaatcag atttcattca
    10681 acctaatgat actgttgcat taattccacc ggttagtgga ggttaaggga gcatgaaagc
    10741 aataattctt gcaggtggtc attcagtgcg atttggtaag cccaaagctt ttgcggaagt
    10801 gaacggtgag accttttata gtagagtaat taagacatta gaatcaacaa atatgttcaa
    10861 tgaaattatt attagtacaa atgcgcaatt ggcaacgcaa tttaaatatc caaatgttgt
    10921 tatagatgat gagaatcata atgataaagg tccattagca ggaatttata caatcatgaa
    10981 gcaacatcct gaagaagaat tgttttttgt cgtttctgtt gatacaccaa tgattactgg
    11041 taaagctgta agcacgttgt atcagttttt agtttctcat cttattgaaa atcatttaga
    11101 tgtcgcagct tttaaagaag atggacgttt tattccaaca attgcatttt atagtccgaa
    11161 tgcattaggc gctataacta aagcactaca ttctgataat tacagtttta aaaatatata
    11221 tcatgaatta tcaacggatt atttggatgt cagggatgta gatgcgccct catattggta
    11281 caaaaatata aattatcagc atgatttgga cgctttaatt caaaaattgt aagctgttag
    11341 gaggtccaca aatggtagaa caaataaaag ataaactagg acgtcccatc cgtgacttac
    11401 ggttatctgt gacagatcgg tgtaacttta ggtgtgatta ttgcatgcct aaagaggtat
    11461 ttggagatga tttcgtattt ttacctaaaa atgaactgtt aacgtttgat gaaatggcta
    11521 gaatcgctaa ggtatatgca gaattaggtg taaaaaaaat acgcattaca ggtggagaac
    11581 cattgatgcg acgcgattta gatgtactta tagctaaatt aaatcaaatc gatggtattg
    11641 aagatattgg tttgactaca aatggtttgt tattaaaaaa gcatggacaa aagttatatg
    11701 atgctgggct acgcagaatt aatgtcagtt tggatgctat tgatgatacg ctatttcaat
    11761 caatcaataa tcgtaatatt aaagcgacta cgattttaga acaaattgat tacgcgacgt
    11821 ctattggttt gaatgtaaaa gtaaatgttg ttatacaaaa aggtattaac gatgatcaaa
    11881 tcataccaat gcttgaatat tttaaagata aacatataga gattcgattt atagaattta
    11941 tggatgttgg taatgataat ggatgggatt tcagtaaagt tgtaactaaa gatgaaatgc
    12001 ttacaatgat agagcagcac tttgaaatcg atcctgtaga accaaaatat tttggggaag
    12061 tagcaaaata ttatcgccat aaggataatg gtgttcaatt tggtttgatt acaagtgttt
    12121 cacaatcatt ttgttctaca tgtacacgcg caaggctgtc atcagatggg aagttttacg
    12181 gatgtttatt tgcaactgtc gatggattta acgttaaagc gtttattcgt tctggcgtga
    12241 ccgacgaaga attaaaagaa caatttaaag ctttatggca aataagagat gatcgatatt
    12301 cagatgagag aactgctcaa acagttgcca atcgtcaacg taaaaagata aacatgaatt
    12361 atattggtgg ttaatgtgta gggaccacta catattaaat cattagagat gttttaatat
    12421 ttctgtctta ctccctaaaa tacaatatta tttattaaag taaaaacggt catatctatg
    12481 ccagatttaa tagaaatgat cgtttttaaa gtttttacaa gttggcgggg ccccaacaca
    12541 gaagctgaca gaaagtcagc ttacaataat gtgcaagttg gcggggcccc aacatagaga
    12601 atttcaaaaa gaaattctac agacaatgca agttggggat caacgaaata aattttgtga
    12661 aaatgttatt tctgtcccac tcccaaaaat cactacataa ttaatcttta agggctcttt
    12721 aacattgatg tcacactcca agtcattgag ttgtaatata tcttttttag gtataaatgt
    12781 tgtcgaataa acaacaagtt gtccaaaaga tataaatcta aacaagatat agccagcaat
    12841 ttaatatttg taatagataa aatgctaagt ttgatatata ataaatttaa gtaattgtat
    12901 aataatatga attacaaaca tctaagaaga aacataggag gcatcatatt atgagtaata
    12961 aagttcaacg ttttatagaa gcagaaaggg agttaagtca gttaaagcac tggttaaaaa
    13021 caacacataa gatttcaatt gaagaatttg tagtactttt taaagtgtat gaagctgaaa
    13081 agattagcgg taaagaattg agggatacat tacattttga aatgctatgg gatacaagta
    13141 aaatcgatgt gattatccgt aaaatctata aaaaagagct tatttctaaa ttgcgttctg
    13201 aaacggatga aagacaagta ttctatttct atagtacttc tcaaaagaaa ttgttagata
    13261 aaattactaa agaaatagaa gtgttaagcg ttacaaacta aaaacttaaa aagcatgcca
    13321 atcagtacat catatttgcg tcttggggac agacaaatga tgaatagaga ttggcatgct
    13381 ttttattttt gaatataaat atttagttca tggcatttct agttacatga cgtccatgaa
    13441 ttaagaagta aacaagcata gtaatgattg ctaaagcggc cataaagccg aagatttcac
    13501 tatatgaaaa catatgagta aataacccaa ggaatgatgg accgaagccg acacctgcat
    13561 ctagaccaac gtaaaaagta gatgtcgcga taccatattt aatcgggggt gagactttta
    13621 tcgcaataga ttgcattgca gatgataaat ttccataccc taaacctagg caagcaccag
    13681 caagtaatat taaccagctt tgatagcttg aaattaagca cacaaatgaa aggaaaagca
    13741 tgataaatgc tggatagaca ataatatttt catttttatc atccatcaat ctaccagcaa
    13801 taggtctagt aattaacgat gctatagcat agcaaataaa gaaatagctt gctgcagtga
    13861 ctaggtgtcg ctctaaagca aatgcttgta aataagttag gattgacgca taggtaacgc
    13921 caattaaaag cataattaca gcaacaggaa tggcctcttt tgcaataaat tgatgaatac
    13981 taaatcttgg tttattaatg acatcagttt cagttttatt atttgttact tcgaaatcaa
    14041 cttttataaa taatgagata atgagtccga gtatgcctaa tatgacacaa ataataaaca
    14101 gtaaatcaat tgcgtatttt gtaataagta acatgcctag aaatgggcca atcgctgtac
    14161 ctaatactaa acttaaggaa aataaactga tgccttcact ttttctatta acaggggtaa
    14221 cgtatgccgc aatagtacct gttgcagttg tcacaactgc agttgcgata ccgtttatga
    14281 gacgtacaaa gattaaaaaa gctaaagatc catcaataaa ataaagtaat tgcgtgataa
    14341 ttaaagcaat taaaccaata aataataatc gtttaggtcc gatttgattt acaaatttac
    14401 ctgtagcaaa tcgaccaatt aaagacccga caataaatag tcctacaact aatccggcta
    14461 atgaatcgga agcgtcgaaa gcttgcttac tatagccagc aataactaca agtaacaaat
    14521 acatgcatag gtatacgata aagttgacaa aaaagttgat tgtaaaactt ttggtgaaaa
    14581 taggtgattt atttaatgag ccttgattag tcattgtgtg cctcctttaa taatatttca
    14641 tgaatttgat tcatcacatt tatggtttct tgcatttgat cttgcgaaat gtttgttttg
    14701 gcaactactg cttgttggag cttttgtaca tcaagacaaa caatctcata taattcatgc
    14761 cctttaggtg ttaaagttaa aaacttttgt cgtttatcct ctaaactgtt ttctactgtt
    14821 ataaggtcat tttctattag agcttttaaa gtttttcttg cagtaggctt ttcaattgca
    14881 cgtctatgtg aaatttcaat gagagtagtg ggctgatgtt tagcgatatc gcgtaagatt
    14941 aaccattgac cataatatat attgtgtttt tccaaaatcg gctctgctaa ttttaaatag
    15001 gggcgatata ttgttataaa actattgaaa aattcttgtg atagcatagt gacatctcct
    15061 aagacaaaat agttagctta gctaaccttt ttacaacaat agtaattata aaacgggagc
    15121 aattagaaat caatatataa ttattaagag caaaaataat tatactttgt taaaataagc
    15181 gtaattacat gtaaataggg ggatactaat gatattgaaa tttgatcaca tcattcatta
    15241 tatagatcag ttagatcggt ttagttttcc aggagatgtt ataaaattac attcaggtgg
    15301 gtatcatcat aaatatggaa cattcaataa attaggttat atcaatgaaa attatattga
    15361 gctactggat gtagaaaata atgaaaagtt gaaaaagatg gcaaaaacga tagaaggtgg
    15421 agtcgctttt gctactcaaa ttgttcaaga gaagtatgag caaggcttta aaaatatttg
    15481 tttgcgtaca aatgatatag aggcagttaa aaataaacta caaagtgagc aggttgaagt
    15541 agtagggccg attcaaatgg aaagagatac acataaagat ggtaaggtaa agtggcaatt
    15601 gctttatata atgaatcagg atgatgatga aattaagcca ccatttttta ttcaatggga
    15661 agaaagtgat tccatgcgta ctaaaaaatt gcaaaaatat tttcaaaaac aattttcaat
    15721 tgaaactgtt attgtgaaaa gtaaaaaccg atcacaaaca gtatcgaatt ggttgaaatg
    15781 gtttgatatg gacattgtag aagagaatga ccattacaca gatttgattt taaaaaatga
    15841 tgatatttat tttagaattg aagatggtaa agtttcaaaa tatcattcgg ttatcataaa
    15901 agacgcacaa gcaacttcac catattcaat ttttatcaga ggtgctattt atcgctttga
    15961 accattagta taaatatacg taagtgctat gagcgagaat gcccatatga ataatgacaa
    16021 gcacaatgga aagaatcgtt aatatattat ttaatcggga tgacttaatt aaaatgaaaa
    16081 agattgataa tataaatgtg aaaaagataa gtataacccg taaactaaag taattcacgg
    16141 tgagaggttg actcaatgtc ataatgattg caacgatgtt cataattata aatagactta
    16201 aaataattgt tctcatatca aacacctcat tgttagatta ttgacattat aacaggggta
    16261 attgtatatg aacattaatg tggttgcttg aggaaaaatt tattcattga agtcaagttg
    16321 gttcatttta gaaatgaata tcgtgttaga tgatgaaagt atattgaagt ataggtaact
    16381 agttgaaaag tattaattgt acgataacat taaatttaac acgaaacata gatataaaat
    16441 gattcacaat taaaatgggt aaatttgaac ttgctaaact attaattgga gcatggacat
    16501 ttcaaaaata agagttcaaa tcttacacaa gctctgaatc gacactataa gatacaaact
    16561 gtataattaa aggtattgtt aaatagaagg agatatcata aatcatggaa aagatgcata
    16621 tcactaatca ggaacatgac gcatttgtta aatctcaccc aaatggagat ttattacaat
    16681 taacgaaatg ggcagaaaca aagaaattaa ctggatggta cgcgcgaaga atcgctgtag
    16741 gtcgtgacgg tgaagttcag ggtgttgcgc aattactttt taaaaaagta cctaaattac
    16801 cgtatacgct atgttatatt tcacgtggtt ttgttgttga ttatagtaat aaagaagcgt
    16861 taaatgcatt gttagacagt gcaaaagaaa ttgctaaagc tgagaaagcg tatgcaatta
    16921 aaatcgatcc tgatgttgaa gttgataaag gtacagatgc tttgcaaaat ttgaaagcgc
    16981 ttggttttaa acataaagga tttaaagaag gtttatcaaa agactacatc caaccacgta
    17041 tgactatgat tacaccaatt gataaaaatg atgatgagtt attaaatagt tttgaacgcc
    17101 gaaatcgttc aaaagtgcgc ttggctttaa agcgaggtac gacagtagaa cgatctgata
    17161 gagaaggttt aaaaacattt gctgaattaa tgaaaatcac tggggaacgc gatggcttct
    17221 taacgcgtga tattagttac tttgaaaata tttatgatgc gttgcatgaa gatggagatg
    17281 ctgaactatt tttagtaaag ttggacccaa aagaaaatat agcgaaagta aatcaagaat
    17341 tgaatgaact tcatgccgaa atagctaaat ggcagcagaa gatggaaaca tctgaaaagc
    17401 aagctaaaaa agcgcaaaat atgattaatg atgcgcaaaa taaaattgct aaaaatgaag
    17461 atttaaaacg agacctagaa gctttagaaa aggaacatcc tgaaggtatt tatctttctg
    17521 gtgcactatt aatgtttgct ggctcaaaat catattactt atatggtgcg tcttctaatg
    17581 aatttagaga ttttttacca aatcaccata tgcagtatac gatgatgaag tatgcacgtg
    17641 aacatggtgc aacaacttac gatttcggtg gtacagataa tgatccagat aaagactctg
    17701 aacattatgg cttatgggca tttaaaaaag tgtggggaac atacttaagt gaaaagattg
    17761 gtgaatttga ttatatattg aatcagccat tgtaccaatt aattgagcaa gttaaaccgc
    17821 gtttaacaaa agctaaaatt aaaatatctc gtaaattaaa acgaaaatag attaacgact
    17881 gaaatctgaa cgctcataag actgtcattt gcgttcagat ttttttacac aatatagaat
    17941 ggttgagtaa aatatttttg aatatagtga aagaggggga agtactgtga taaaaaagct
    18001 attacaattt tctttgggga ataagtttgc tatcttttta atggttgttt tagttgtctt
    18061 gggcggtgta tacgcgagtg ctaaattgaa attagaatta ctaccaaatg tacaaaatcc
    18121 agttatttca gttacaacaa caatgccggg tgcaacgcca caaagtaccc aagatgaaat
    18181 aagtagtaaa attgacaatc aagtaagatc gttggcatat gtgaaaaatg ttaaaacgca
    18241 atccatacaa aatgcttcaa ttgtaacagt tgaatatgaa aataatacag atatggataa
    18301 agcagaagaa cagcttaaaa aagaaatcga taaaattaaa tttaaagatg aagttggtca
    18361 accagaatta agacgtaatt cgatggacgc ttttccggtt ttagcatatt cattttcaaa
    18421 taaagagaat gacttgaaaa aagtaacgaa agtactgaat gaacaattaa taccaaaatt
    18481 acaaacggta gatggtgtgc aaaatgcgca attaaatggg cagacgaacc gtgaaatcac
    18541 ccttaaattt aagcaaaatg aacttgaaaa atatgggttg actgctgatg atgtagaaaa
    18601 ctatctaaaa acagcaacaa gaacaacacc acttggattg ttccaatttg gtgataaaga
    18661 taaatcaatt gttgttgatg gtcaatatca atctgttgat gcttttaaaa acataaatat
    18721 tccattaacg ttggcaggag ggcaagggca atctcaatcc caaagtgata ataaacaaaa
    18781 ttcagccatg tcagacgtta atcaggcatc accgcagcaa aattcaaaag cgtcagcacc
    18841 aaataatata agtggtatgc cgacagcgaa actaggagat ttagctgata ttacagttgg
    18901 tgatgtgcgt acttctattt ctaaaacgaa tggaaaggat gcggttaatc tacaaataac
    18961 taaagctcaa gatgccaata cagttcaagt agccaaagat gtacaacgta aaattgatac
    19021 attcgttgat gaaaataaag attttaatgt cacaaaaaca atggatactg caaagcctgt
    19081 tgagaaatca ctttatacga tggttgaaaa agcatcatta ggtacaatcg tggcaattat
    19141 agttattttg ctgtttttaa gaaacattcg tacgacggca atttctatta tatccattcc
    19201 gttatcactt cttatggcgc ttattgctct gaaattgagt gatgtttcat tgaatatact
    19261 aacgttaggt gcattaacag tagcgattgg acgtgtgata gacgattcga ttgtagttgt
    19321 tgaaaatatt tatcgacgct taacagattc agaagaacaa ctaaaaggtg aaaatttaat
    19381 tatcagtgcg acaactgaag tatttaaacc aataatgtca tcgacactag ttactattat
    19441 cgtcttctta ccacttgtgt ttgtatcagg ttcagtaggc gaaatgttta gaccttttgc
    19501 attggctatt gcatttagtt tattagcatc gttattagtg tcaattacac tcgttccagc
    19561 tttggcagca acactattta aaaaaggcgt taaacgtcgt aataaacaac atcaagaagg
    19621 attaggtgtt gttagtacaa cttataaaaa agtattgcat tggtcactaa atcataagtg
    19681 gattgtaatt atattaagta cattaatttt ggttgcaact attgtatttg gaggaccgag
    19741 actaggcact agctttattt cagcaggtga cgataaattt ttagctatta cttatacacc
    19801 gaagcctggt gaaacggagc aagcagtgtt gaatcatgcg aaagatgttg aaaaatattt
    19861 aaaacagaaa aagcatgtaa aaacaattca atactcagtt ggtggtagta gtccagtaga
    19921 tccaacgggt agtacaaata gtatggcaat catggttgaa tatgataatg acacgcctaa
    19981 ttttgatgta gaagcggata aggttattaa acatgtagat ggctttaaac atcctggaga
    20041 gtggaaaaat caagatttag gaacaggtgc aggtaataaa tctgtagagg ttactgtgaa
    20101 aggcccatca atggatgcca taaaatcaac tgtaaaagat attgaacaga aaatgaaaca
    20161 ggttaaagga ctagccaatg tcaaatctga tttatcgcaa acatatgatc agtatgaaat
    20221 taaagttgat caaaataaag cggcagaaaa tggtatttct gcaagtcaac ttgcaatgca
    20281 cttgaatgaa aacttaccag aaaaaacagt tacgactgtt aaagaaaatg gtaaaactgt
    20341 tgatgttaaa gtcaaacaaa ataagcaaac agactggtca gaagataagt tgaataatat
    20401 aactttgaaa aagccgactg gtggtacgat taaattggga gatatcgcta cgttagttaa
    20461 aacaacgaca ccaagtaaat tgacgcaaga acaaggtgat tatgcaacga cggtatctgc
    20521 taaagtaaca aataaagatg tgggtggcac aacacgacaa gtgatgtcta aaataaataa
    20581 tttggacaaa ccgaataatg taaaggttaa tatcggtggt gcatcagatg atattaacaa
    20641 tgcaatgaca caattagcct ttgcaatgtt agctgcaatc attatcgtat atttaatcct
    20701 agttattaca tttaaaggtg gcttagcgcc atttacaatt ttattctctt taccatttac
    20761 agttatcggt gtaattattg cactattaat cacaggagaa acaatatcag taccaagttt
    20821 aattggtatg ctaatgttaa ttggaatcgt agtaacaaat gccattgtgt taatagaccg
    20881 tgtcattaat aatgagcagc agggcatgga gatgaaagaa gcattaatcg aagcaggcgg
    20941 tactagaatt agaccgatat taatgacggc gattgcaaca atcggtgcat tagttccttt
    21001 gttatttggt caagatagct cgattcttat ttcgaaagga ttagctgcta cagttattgg
    21061 tggtttaatt tcatcaactt tattaacact tgtagttgta ccagtaatat atgaaattct
    21121 ctttacttta aaaaaacgat tcactaaacg atagataata taaaagccat aaaagcggtc
    21181 atgatattga ctacttttat ggctttttaa aatttgaaat tttagacctt atttcacgtg
    21241 cgatttaatc gatgtgttaa taaaacaata ctggcattca acatgtacga taataaaata
    21301 aaattgcaat tatgttattg catgttttgt ttattattta gaataatacg atggttaaga
    21361 tgaaatatat gacaaagata aataatgaca ttaaattcaa gatgtttaca ccttttagat
    21421 cttttttaag cattttaaat cctgtcactt cgacattgcc gactaagagt agtaagacga
    21481 taaataccca ccaattatct tttggaaaac tcatcgtcgt taatgctaag acgaacaata
    21541 acaacacacc cataataatt ctcaaaatgc gagtaaatac aacttccatt ttaaaaatac
    21601 taataaaact aacaattaga taaagtattg ctagtaaaat cagataaaat tgcatatgat
    21661 aacttcctct ccgtttcaaa gggttcatgt agtacagcag catagaaaac ataaatagca
    21721 gtgttgggat agatatgcgt gtatgttgtt aatgaaacac taaatcataa cacgacaaca
    21781 tcttgtgatt ctagatgtaa ttgagcgaaa aataaagcaa ttcatcaata taacgtattc
    21841 agagcaatgc tagtcaaatt tatgtaacga aaagcattta ttgcttgaat gatagattat
    21901 taatcttgca tttgagcgcg aacgtttcta atttcatttt caatatcttt aagttgacga
    21961 acaagtgcgg aagtatctaa attcaaagat tcccgttttt ctaagtcacc ttgaagacga
    22021 acataatcat atttaagttc ggctagttgg ttttctaaag acatactata acactccttt
    22081 gaaatataat taagtgcatt taatgtagat tatagcatga aacagtagac ttctaaaata
    22141 tctgtggagt atgttaaagt tataaattat gaagattatt gaaagaaggg ataacagtga
    22201 cagaacaatt tactatgatt attttattaa ttgcgcttgg ttactttttg aagcgcatta
    22261 attttataaa ggcaacagat agtcaagtca ttgctacatt agttcttaat gtcacactcc
    22321 catctttagt tattgtgaat ttaaacagtg cagaattaaa attgtcattc tccattttac
    22381 caattttaat gattatatat ggtattgtgg cgaaaatgat tgctgtctgg ttttttagaa
    22441 aatatgataa tcacatgcgt ggatcagtag gtatgatgac tggtgctatg aatattggat
    22501 tgtttgcata tccactaatt gaagtgatat ggcctaaaac ggggcttatt tattttggta
    22561 tggctgatat aggtggtgcc tttgtgatgt ttggaattac ttactttgta ggtagctact
    22621 ttagtgaagg tagtgatcaa ttcgatttta aatatttagg taagaaatta ttacagtcag
    22681 tgccactcgt tacatacatt gtaatgttta tattgaatat aaatcacatc catttaccac
    22741 atgtggcaat cgatttcttt agcatacttt cccatgcaaa tatgccgtta tcaatgattt
    22801 tgctaggtgt tatgttgaat tttactctgg aaagaaagta tatacctgct actattaaat
    22861 atttatgttt gcattatgga ttagcattag ttgcgggatt gttagtacat gtgttgttac
    22921 cggtatcaga tgatatgatt aagacgacat tgttggtcac ttggatgttc ccggttggtg
    22981 tcgcaattat ttcttatggt attcagttta aatatcgaac actgccattt ataggtatga
    23041 cgaccaattt gacaatcatt attagtatca ttattttgta cgtgtatcag gcagtgtttg
    23101 tctagtttac acatttgaaa ataaaatcca ttttagtatt cgtagaaaat gagagccccc
    23161 tttaccacaa catgtaaatg catattgtga aaagggggct tttatttatg acatagttgt
    23221 tcaacaggcc gggacataaa tcaatattct atgctctacg aagttatatt ggcagtagtt
    23281 tactgaacga aaatgcgctt gtaacaagct tttttcaatt ctagtcaggg gccccaacac
    23341 agaagctgac gaaaagtcag cttacaataa tgtgcaagtt ggggaggggc cccaacaaag
    23401 agaaattgga ttcccaattt ctacagacaa tgcaagttgg ggtgggacga cgaaatatat
    23461 tttgcgaaaa tatcatttct gtcccactcc ctatgcagct atccacttca tatgtatggc
    23521 gcatacttga taaatgaata tcatcaagat tttaaaagta tcgctaattt taaagtctta
    23581 aaacgcatga ttaatgtcat gatgtgttat tgcgttttgt ttttagagcc acgtatttcc
    23641 taggacatat agaggaacat tcaacgtaaa attcccgaaa attaatttta atcattctat
    23701 aagtgaatgg ttattttcag aagtgattac atttttacgt tacatgagta tttaactttc
    23761 tatttcaaat tacctagaat tatagcagct atcacgataa taataatacc tgcccaaata
    23821 cccgtcatct gacgacgatc ttttctttct cctaaaatga aaataccacc taatgttgaa
    23881 acgataacaa gtaactgtga taatgagaaa cttgtagcta caccaacttt tggttgagaa
    23941 tagaacatga acaagttacc aattccccaa atcacacctg gcaatagatt aagtgctgtt
    24001 gatttaagtg atgttttatg attcatggat aggataaagc caccaattgc cataccgaca
    24061 gattggaaga acaatgcatc agttccacca acaccaaaga tgtcaccaag tacaacgaaa
    24121 cctacatatc caactgtaga tacaattaaa atacccattg cttttttaaa ttcaggatta
    24181 tctgattgac gttcattttt ggctttaagt gaagtaagtg ctacaccagt aactaataat
    24241 atcatggcga ttaaaccaaa gataatttga gtcattgaag accattcacc taaaaagata
    24301 acgctgaata atgttgtacc aactaattgc atacctgtag aaactggcat agtatttgat
    24361 acaccgatta aactaataga tttaagctga ttcgcttgtc caaacgccca taatgcacca
    24421 gaaataagac cgacaataat tacagtagga ttattgaatt ttgcgaaacc agtaataagt
    24481 aaacctaatc caacaatgag tgcgcctagc gtcgtaccac gaatttggtt gtaaggtcca
    24541 ccgccgacga acacattaat aagaacgaca cttccccaga ataaagcagg tgaaagtgcg
    24601 attaagaaat caagaaattg caagactact cactctccta tactattttt gcaagtgctc
    24661 cccttaattg acacttgcat gttattgtaa agcattctgc cctaatagta aaaaacaact
    24721 acttataatt ttcaatattt acaaaaagta gaaaaaccca caatacatgc taatgaagta
    24781 ctgtggggta tttgcttggt attttattca gggattgttt gatcttttac gttacgtgat
    24841 tcgaatttga atttaatgta ctcatagttg atatggaaac ctagaccatt aaatcgttcg
    24901 atgagtttat tatttttatt acgaatttta aaataaactt ttctaatatc aaaattatca
    24961 aaagcatatt gcaatgcata cgcaagcaac tcgaaagcga tacctttcaa acggtaatct
    25021 acatgagaac tgaagtattt aatctcggcg attgactgtt gtgaatcaat ttcaaggtat
    25081 aaataacctt taagtaaacc ttcgctaaca aataaaaaca aatgatgatg gtcgtctaaa
    25141 ctatcaatga tatcttgcgg tgactgtgcc tgatatttaa atgtagttgt gtgtaatttg
    25201 ctgaaagcac gataaaaccc tttgtgataa ggaatgatat ttggttggtg catatcttct
    25261 tctaatcttg tacgggcttc tatgtaatag tcagtgaagt tataacttgc ttgaataact
    25321 ttcattaatg gtttgtattg ttgaatgcct tcttcaaaag aaaagttaaa gacggcatcg
    25381 tcaggttggt tcgaagtcat tgctttaaat agcgtttcaa acgtatcgac agataataca
    25441 taattgtcag ccacgaatgg gcctatgact ttgaatttat ttttatcgta tgcaaaagac
    25501 aatatgattg ctttgattga atcgttttct ttaatcgaaa atacaccagg tgattcaatc
    25561 gcatcggtta ttaatacatc tatttcattg tactgttgag gaagtttata taagtatgat
    25621 gctgattcat aattcgaatg ttcaatgaac gattttattt gtgtaatatc atataactga
    25681 actatgctca tgtcattacc tccgtacttt ttgttacttt tattatatag tatttcaact
    25741 gaaatgaaag ttaatagtga tattaacatg ttacaataca tttaacacca ttgaatttaa
    25801 atcaaagatt agtggaatag atgaagcacg ttcgaaataa aagaacgtat gagaaaggat
    25861 aatttatgaa atctttaata ttagctgaaa aaccatcagt tgcaagagat attgctgatg
    25921 ctttacaaat aaatcagaag cgtaatggtt actttgaaaa taaccaatat attgtcacgt
    25981 gggcgttagg tcatctagtg acaaatgcga cacctgaaca atacgataaa aatttaaagg
    26041 aatggcgatt agaagacctt ccaattatac ctaaatatat gaaaactgtt gttattggta
    26101 aaacaagcaa acaatttaaa acagtaaaag cgttaatttt agataataaa gtgaaagata
    26161 ttattattgc aacagatgct ggacgagaag gtgaactagt tgcaagattg attttggata
    26221 aagttggtaa caaaaagcca atccgtcgat tatggattag ctcagttact aaaaaagcta
    26281 ttcaacaagg ttttaaaaat ttaaaagacg gtcgtcaata taacgatttg tattatgcag
    26341 cgttagcgag aagcgaggca gattggattg ttgggattaa tgcaacgcgt gcactaacaa
    26401 caaagtatga tgcacagcta tccctgggac gtgttcagac accaacgatt caattagtaa
    26461 atacacgaca acaagagatt aatcagttca aaccacaaca atactttaca ttatcattaa
    26521 cggtaaaagg gtttgatttt cagctagaat caaatcagcg atataccaat aaagaaactt
    26581 tagaacagat ggttaataat ttgaaaaatg tcgatggtaa gattaaatct gttgctacta
    26641 aacataagaa gtcgtatccg caatcactgt acaatttaac agatttacaa caagatatgt
    26701 atagacgtta taaaattgga cctaaagaaa cattgaatac acttcaaagc ttatatgaga
    26761 gacataaagt cgtaacctat ccaagaacag attcaaacta tttaacaact gatatggtag
    26821 atactatgaa agaacgtatt caggcgacga tggcaacaac atataaagac caagcacgcc
    26881 cattaatgtc taaaacattt tcatcaaaaa tgtcgatatt taataatcaa aaagtatctg
    26941 atcaccatgc aattattcct acagaagtga gacctgtcat gtcagactta agtaatagag
    27001 aattaaagtt atacgatatg attgtcgagc gttttttaga agctttaatg cctccgcacg
    27061 agtatgacgc gataactgta actttagagg ttgcagggca cacatttgtt ttgaaagaga
    27121 atgtaacaac tgttttaggt tttaaatcta ttagacaagg tgaatctatt acagagatgc
    27181 aacagccttt ttcagaaggc gatgaagtga agatttcaaa aacaaacatt agagaacatg
    27241 aaacaacacc tccagaatat tttaatgaag gttcgttatt aaaagcgatg gagaaccctc
    27301 agaactttat tcaattgaag gataaaaaat atgcgcaaac tttaaaacaa acaggtggta
    27361 tcggcacagt tgcaacaagg gccgacatta tcgataaatt atttaatatg aatgccattg
    27421 aatcaagaga cggtaaaatt aaagtaacgt caaaaggtaa acaaatatta gaattagcac
    27481 cagaagaatt aacgtcgcca cttttaactg cacaatggga agaaaaatta cttttaattg
    27541 aacgtggtaa atatcaggcg aaaacattta ttaatgaaat gaaagatttt acgaaagatg
    27601 ttgtaaatgg gattaaaaat agtgatcgta aatataaaca cgataattta acaaccacag
    27661 aatgcccaac gtgtggtaaa ttcatgatta aagttaaaac taaaaatggt cagatgcttg
    27721 tgtgccaaga tccatcttgt aagacgaaaa agaatgtaca gcgcaaaaca aatgcaagat
    27781 gtccaaactg taaaaagaaa ttaacgttgt ttggtaaagg gaaagaagcg gtatatcgtt
    27841 gtgtttgtgg acattctgaa acgcaagcac atatggatca gcgtatgaag tctaaatcct
    27901 ctggtaaagt atctcgtaaa gaaatgaaaa agtatatgaa taaaaatgaa ggtttagaca
    27961 ataatccgtt taaagatgca ttaaagaact tgaatttata gataaaatcg aacaaagttg
    28021 aatcagaaaa acgaaaagtt cgcttttggt attgtttttt attaagaatg atattaaact
    28081 attaaggtat tttaaaaaaa ggagcatcca ttcgtgaaaa actatttcca gttcgataaa
    28141 tatggaacaa actttaaaag agaaatctta ggcggtatca caactttctt atctatggcc
    28201 tatattttag cagttaaccc gcaagtttta agtttagcag gtgttaaagg cgtatcagaa
    28261 gatatgaaaa tggaccaagg tgccattttt gtagcgactg cattagcagc atttgtaggc
    28321 tcgctattca tgggactaat agctaaatat ccaatcgcat tagcaccagg tatgggatta
    28381 aatgcattct ttgcatttac tgttgtgtta accatgggta ttccttggca agttggttta
    28441 acaggtgttt tattctcagg tatattcttt gcgatattaa ccgtcacagg gtttagggaa
    28501 gttattatta atgcaattcc ttatcaaatg aagatggctg tttcagcagg tataggatta
    28561 ttcattacat ttgtaggttt acaaagttcg ggtattatag ttaaaaatga atctacatta
    28621 gtaacattgg gacatttaac tgatccacca gtacttttgg cgatattcgg tatcgttatt
    28681 acagttattt tatatgcaat taaattgccg ggttctatct ttatcggtat gatcatcaca
    28741 gcaatcgttg gtatgttcac tggattgatt caaatgccat ctggtattgt aggtaagatt
    28801 ccaagtattg aaccaacgtt cggtgctgca tttgaagcgt ttaaagaccc aagtcaatta
    28861 ttaacgatac agttcttaat tgttatttta acgttcttat ttattgattt ctttgataca
    28921 gctggtacat tagtagctgt tgctactcaa gcaggtatta tgaaagataa taaattacca
    28981 agagctggta gagcattgtt ctcagattct ttagctacga ttgtaggatc agtttttgga
    29041 acaactacaa caacttctta tatcgaatca acttcaggtg ttgctgtagg tgctagaaca
    29101 ggatttgcta gtatcgtaac aggttgttgt ttcctattag cgctgttctt tagtccgtta
    29161 atcgctgttg taacaagtgc agttacgaca ccagctttag tggtggtagg tgtattaatg
    29221 gctgcaaact ttgctgagat aaactggaaa agttttgaag ttgcagtgcc agcattcatt
    29281 acaatcatta tgatgccttt atcatactca attgcaactg gtattgcgtg tggatttatt
    29341 ttctatccaa ttacaatgct tatctctaaa aaacaaaaag aagtacatcc gataatgtat
    29401 gtattaatgg tactattcat tctgtacttc atatttgttc atggttaaat ccagacacaa
    29461 aaaacgactg ccaatgattg gtagtcgttt tttctttgaa gtaaggataa aataagaagc
    29521 gaaataacat aaagcaatat tatgaatgtc tttaaatatc cgatataaat atacttcttt
    29581 taaaattgtt ggacgtgttt cttctatatt atatacctaa ttaaaaaggt tttaagaatt
    29641 attctctatg tccatctttg tattgtgtgt aaatgacacg agcattttta ttaggtatat
    29701 aggttggcgc tgataataca actaggacaa atagaatcat taggaaaaat aaaatccaat
    29761 gaatcaaaat tcctaagaag gggatgatag ctaaaaaact acctactata ccaaatattg
    29821 gaataatcgc tataggtcta atcgcatttt gtctattcac taataatata atagtaagaa
    29881 ttagataaag taatgcatta aagagtaaag gctgccatcc aaaacttaaa ataaacgttg
    29941 cacctaaaaa aggaatgcca tagaaaaact cacaaagtat taaaaagata cctataagtg
    30001 ctaaagataa ttttggtcca tttttcatat tcattcacca ccgttcttat gactaattat
    30061 atagaataat tttcaatgat aataataaaa tgattcaagg tacgaattta caataaagaa
    30121 ggaaataaaa aatatctcga aaatagttga actgactaag tatataaagt aaaatataaa
    30181 agtatgtgtt agacagatag aaaaattatg tgaaaagcct tgatttatcg atgtttttcg
    30241 tgtaatataa ctaacgttgg actttaagaa aagcgatgaa gcgaaaggtt actgacacac
    30301 ccggccgctt tgccatggcg ctgtgtaaga tagttttcgt ggagaagtct atcactaaat
    30361 gtagacgaat aaggagggaa aattatggca aaacaaaaaa tcagaatcag attaaaagct
    30421 tatgatcacc gcgtgattga tcaatcagca gagaagattg tagaaacagc gaaacgttct
    30481 ggtgcagatg tttctggacc aattccgtta ccaactgaga aatcagttta cacaatcatc
    30541 cgtgccgtgc ataagtataa agattcacgt gaacaattcg aacaacgtac acacaaacgt
    30601 ttaatcgata ttgtaaaccc aacaccaaaa acagttgacg ctttaatggg cttaaactta
    30661 ccatctggtg tagacatcga aatcaaatta taatagacaa ttttaggagg tggactttcg
    30721 atgaccaaag gaatcttagg aagaaaaatt gggatgacac aagtattcgg agaaaacggt
    30781 gaattaatcc ctgtaacagt agtagaagct aaagaaaatg ttgtattaca aaagaaaact
    30841 gtagaagttg atggatacaa cgcaatccaa gttggatttg aagacaaaaa agcatacaaa
    30901 aaagatgcaa aatctaataa atatgctaat aaaccagctg aaggtcacgc taaaaaagct
    30961 gacgcagcac ctaagcgctt cattcgtgaa ttccgcaatg tagacgtgga tgcttacgaa
    31021 gtaggtcaag aagtctcagt agatactttt gtagctggcg acgttattga cgtaacaggc
    31081 gtatcaaaag gtaaaggttt ccaaggtgca attaaacgcc acggacaatc tcgtggacct
    31141 atgtcacacg gttctcattt ccacagagca ccaggttctg taggtatggc ttcagatgct
    31201 tctagagtat ttaaaggcca aaaaatgcca ggacgtatgg gtggaaacac tgtaactgtt
    31261 caaaacttag aagtagttca agttgacaca gaaaacaaag ttatcttagt aaaaggtaac
    31321 gtacctggac ctaaaaaagg tttagtagaa atcagaactt caattaaaaa aggtaataaa
    31381 taataagaag tgaaaggagg aaatgcataa tggctaatta tgatgtttta aaattagacg
    31441 gaactaaatc aggttcaatc gaattaagcg atgcagtatt cggtattgag ccaaataata
    31501 gcgttttatt cgaagctatt aatttacaac gtgcttcatt acgtcaaggt acgcatgctg
    31561 ttaagaatcg ttcagcagta agcggtggcg gacgtaaacc atggaagcaa aaaggaacag
    31621 gtcgtgctcg tcaaggtaca atccgtgctc cacaatggcg tggcggtggt atcgtattcg
    31681 gaccaactcc aagaagttat gcatacaaaa tgcctaagaa aatgcgtcgt ttagctttac
    31741 gctcagcatt atctttcaaa gctcaagaga atggcttaac tgtagttgac gcattcaact
    31801 tcgaagctcc aaaaactaaa gaattcaaaa atgtattatc tacattagaa caacctaaaa
    31861 aagtattagt agttactgaa aacgaagatg taaatgttga attatcagca cgcaacatcc
    31921 ctggcgttca agtgacaact gctcaaggtt taaatgtttt agatatcact aatgctgaca
    31981 gcttagtaat tactgaagct gctgctaaaa aagttgagga ggtgctcgga taatggaagc
    32041 aagagatatt cttaagcgcc ccgtaatcac tgagaaatct tctgaagcaa tggctgaaga
    32101 caaatacact ttcgacgttg atactcgtgt taacaaaaca caagtaaaaa tggcagttga
    32161 agaaatcttc aacgtaaaag ttgcaagtgt taatatcatg aattacaaac ctaagaaaaa
    32221 acgtatgggc cgttaccaag gctatacaaa caaaagaaga aaagcgattg taactcttaa
    32281 agaaggatca atcgacttat ttaactaata aaacaattac cattaaggag gtaagcgaca
    32341 atggctatta aaaagtataa gccaataaca aatggtcgtc gtaatatgac ttcgttagat
    32401 ttcgcagaaa tcacgaaaac tacacctgaa aagtcattat taaaaccgct accgaaaaaa
    32461 gcgggacgta acaaccaagg taaattgact gtaagacacc atggtggtgg acacaaacgt
    32521 caataccgtg ttatcgattt taaacgtaac aaagatggta tcaatgcaaa agttgattct
    32581 attcaatatg atccaaaccg ctcagcaaac atcgctttag ttgtatatgc agacggtgaa
    32641 aaacgatata tcattgctcc taaaggatta gaagtaggtc aaatcgttga aagtggtgct
    32701 gaagctgaca tcaaagttgg taacgcatta ccattacaaa acattccagt tggtacagta
    32761 gtacacaaca tcgagcttaa acctggtaaa ggtggacaaa tcgctcgttc agctggtgca
    32821 agtgctcaag tacttggtaa agaaggtaaa tacgtattaa tcagattaag atctggtgaa
    32881 gttcgtatga tcttatctac ttgccgtgct acaatcggtc aagttggtaa cctacaacac
    32941 gaattagtta acgttggtaa agccggacgt tcaagatgga aaggtatccg tccaacagtt
    33001 cgtggttctg taatgaaccc taacgatcac ccacacggtg gtggtgaagg tcgtgctcct
    33061 atcggtagac catctccaat gtcaccatgg ggtaaaccta cgcttggtaa gaaaactcgt
    33121 cgtggtaaaa aatcatcaga caaacttatc gttcgtggac gtaagaaaaa ataatataat
    33181 caacttattt gggtgtgcgg cttaaagctg cacgcacata ataagaaggg aggcgcccaa
    33241 atggctcgta gcattaaaaa aggacctttc gtcgatgagc atttaatgaa aaaagttgaa
    33301 gctcaagaag gaagcgaaaa gaaacaagta atcaaaacat ggtcacgtcg ttctacaatt
    33361 ttccctaatt tcatcggaca tacttttgca gtatacgacg gacgtaaaca cgtacctgta
    33421 tatgtaactg aagatatggt aggtcataaa ttaggtgagt ttgctcctac tcgtacattc
    33481 aaaggacacg ttgcagacga caagaaaaca agaagataat atctattaag tagaggagga
    33541 catcctaatg gaagcaaaag cggttgctag aacaataaga atcgcacctc gtaaagtaag
    33601 actagttctt gacttaatca gaggtaaaaa tgctgctgaa gctattgcaa ttttaaaatt
    33661 aacaaacaaa gcttcatcac cagtaattga aaaagtatta atgtccgctt tagctaatgc
    33721 tgaacataac tatgacatga acacagatga attagtagtt aaagaagcat atgctaacga
    33781 aggaccaaca ttaaaacgtt tccgtccacg tgcgcaaggt cgtgcaagtg cgattaacaa
    33841 acgtacaagc cacattacaa tcgtcgtaag tgacggtaaa gaagaagcta aagaagctta
    33901 attaactttt aaggagggaa tactgtgggt caaaaaatta atccaatcgg acttcgtgtt
    33961 ggtattatcc gtgattggga agctaaatgg tatgctgaaa aagacttcgc ttcactttta
    34021 cacgaagatt taaaaatccg taaatttatt gataatgaat taaaagaagc atcagtttct
    34081 cacgtagaga ttgaacgtgc tgcaaaccgt atcaacattg caattcatac tggtaaacct
    34141 ggtatggtaa ttggtaaagg cggttcagaa atcgaaaaat tacgcaacaa attaaatgcg
    34201 ttaactgata aaaaagtaca catcaacgta attgaaatca aaaaagttga tcttgacgct
    34261 cgtttagtag ctgaaaacat cgcacgtcaa ttagaaaacc gtgcttcatt ccgtcgtgta
    34321 caaaaacaag caatcactag agctatgaaa cttggtgcta aaggtatcaa aactcaagta
    34381 tctggtcgtt taggcggagc tgacatcgct cgtgctgaac aatattcaga aggaactgtt
    34441 ccacttcata cgttacgtgc tgacatcgat tatgcacacg ctgaagctga cactacttac
    34501 ggtaaattag gcgttaaagt atggatctat cgtggagaag ttcttcctac taagaacact
    34561 agtggaggag gaaaataata atgttactac caaaacgtgt aaaatatcgt cgtcaacatc
    34621 gtcctaaaac aactggtcgt tctaaaggcg gtaactacgt aacatttggt gagtttggtt
    34681 tacaagctac aacaacgtct tggatcacat ctcgtcaaat cgaatctgct cgtatagcaa
    34741 tgacacgtta catgaaacgt ggcgggaaag tttggattaa aatcttccca catacaccat
    34801 atactaaaaa acctttagaa gtacgtatgg gtgctggtaa aggtgcggtt gaaggctgga
    34861 tcgcagttgt taaaccaggt agaattttat tcgaagttgc tggcgtttct gaagaagttg
    34921 cgcgtgaagc actacgttta gcaagtcaca aacttccagt aaaaactaag tttgtaaaac
    34981 gtgaggaatt gggtggtgaa acaaatgaaa gctaaggaaa ttagagactt aaccacttca
    35041 gaaatcgaag aacaaatcaa atcttcaaaa gaagagcttt ttaacctacg ctttcagtta
    35101 gctacaggtc aattagaaga aactgcacgt attcgtacag taagaaaaac gattgcacgt
    35161 ctaaaaactg ttgctcgtga aagagaaatt gaacaaagta aggctaatca ataattaagt
    35221 aagaggaggt tacaaaagtg agcgaaagaa acgatcgtaa agtttatgta ggtaaagttg
    35281 tttcagacaa aatggacaag actattacag tacttgttga aacttacaaa acacacaaat
    35341 tatacggtaa acgagtaaaa tactctaaaa aatacaaaac tcatgatgaa aacaattcag
    35401 ctaaattagg agacattgtt aaaattcaag aaactcgtcc tttatcagca acaaaacgtt
    35461 ttcgtttagt agagattgtt gaagagtcag taattattta atacaagttt agagataagg
    35521 gaggtttaac taatgatcca acaagaaaca cgcttgaaag tagcagacaa ctctggtgct
    35581 cgtgaagttc ttacaatcaa agtattaggt ggatctggtc gtaaaacagc aaatatcggc
    35641 gatgttatcg tatgtactgt taaaaatgca acaccaggtg gcgttgttaa aaaaggtgac
    35701 gttgtcaaag ctgtaatcgt acgtactaag tcaggtgttc gtcgtaatga cggttcatac
    35761 atcaaatttg atgaaaatgc atgtgttatc atccgtgatg acaaaggccc acgtggtact
    35821 cgtatcttcg gacctgttgc tcgtgaatta cgtgaaggta acttcatgaa aatcgtatca
    35881 ttagcaccag aagtacttta attaataaca accaatacaa ataaggaggt gcccacatgc
    35941 atatcaaaaa aggtgacaac gttaaagtta tcgcaggtaa agacaaaggt aaagaaggta
    36001 aagtaattgc tactctacct aaaaaagacc gtgtcgttgt ggaaggtgtt aacattatga
    36061 aaaaacacca aaaaccaact caattaaatc ctgaaggtgg aatcttagaa acagaggcag
    36121 caatccatgt ttctaatgta caattattgg accctaaaac aaacgaacca actcgtgtag
    36181 gttacaaatt tgttgatggt aaaaaagttc gtatcgctaa aaaatctggc gaagaaatta
    36241 aatctaataa ttaataacaa gttgaaagga ggatcccact ttgaaccgtt taaaagaaaa
    36301 gtttaacact gaagttactg aaaacttaat gaaaaaattc aattatagtt cagtaatgga
    36361 agtaccaaaa atagataaaa tcgttgtgaa catgggtgta ggtgacgcag tacaaaattc
    36421 taaagtatta gacaatgctg ttgaagaatt agaattgatc actggtcaaa aaccattagt
    36481 aactaaagct aaaaaatcaa tcgcgacttt ccgtttacgt gaaggtatgc caatcggtgc
    36541 gaaagtaaca cttcgcggtg aaagaatgta tgaattctta gacaaattaa tttcagtatc
    36601 attaccacgt gtacgtgact tccaaggtgt ttctaaaaaa gcatttgacg gacgcggtaa
    36661 ctacacttta ggtgttaaag aacaattaat tttcccagaa atcgactatg ataaagtaag
    36721 taaagttaga ggaatggata ttgttatcgt aacgactgct aacactgatg aagaagctcg
    36781 tgaattgtta gctaacttcg gtatgccatt ccgtaaataa ttatttaaag gaggctaatt
    36841 aagtggctaa aacttcaatg gttgctaagc aacaaaaaaa acaaaaatat gcagttcgtg
    36901 aatacactcg ttgtgaacgt tgtggccgtc cacattctgt atatcgtaaa tttaaattat
    36961 gccgtatttg tttccgtgaa ttagcttaca aaggccaaat ccctggtgtt cgtaaagcta
    37021 gctggtaata aaaaagagtc tgaaaggagg caacaatcaa tgacaatgac agatccaatc
    37081 gcagatatgc ttactcgtgt aagaaacgca aacatggtgc gtcacgagaa gttagaatta
    37141 cctgcatcaa atattaaaaa agaaattgct gaaatcttaa agagtgaagg tttcattaaa
    37201 aatgttgaat acgtagaaga tgataaacaa ggtgtacttc gtttattctt aaaatatggt
    37261 caaaacgatg agcgtgttat cacaggatta aaacgtattt caaaaccagg tttacgtgtt
    37321 tatgcaaaag ctagcgaaat gcctaaagta ttaaatggtt taggtattgc attagtatca
    37381 acttctgaag gtgtaatcac tgacaaagaa gcaagaaaac gtaatgttgg tggagaaatt
    37441 atcgcatacg tttggtaata aaaaataagg aggtgccata acatgagtcg tgttggtaag
    37501 aaaattattg acatccctag tgacgtaaca gtaacttttg atggaaatca tgtaactgtt
    37561 aaaggtccta aaggtgaatt atcaagaact ttaaatgaaa gaatgacatt caaacaagaa
    37621 gaaaacacaa ttgaagttgt aagaccatct gattctaaag aagatagaac aaaccatggt
    37681 acaactcgtg ctttattaaa caatatggta caaggtgttt ctcaaggata cgtaaaagta
    37741 cttgaacttg ttggtgtagg ttaccgtgct caaatgcaag gtaaagactt aatccttaac
    37801 gttggttatt ctcacccagt agaaattaaa gctgaagaaa acattacttt ctcagttgag
    37861 aaaaacacag tcgttaaagt tgaaggtatt tcaaaagaac aagttggagc attagcatct
    37921 aacatccgtt cagtaagacc tccagagcct tacaaaggta aaggtattcg ttaccaaggt
    37981 gaatacgttc gccgtaaaga aggtaaaact ggtaaataat agataaactc taaagaaagg
    38041 agtattgaaa tgatcagtaa aattgataaa aataaagtgc gtttaaaaag acatgctcgt
    38101 gttcgtacta acttatcagg tacagctgaa aagccacgtt taaacgtata tcgttcaaac
    38161 aagcatatct acgctcaaat tattgatgat aataaaggcg taacattagc tcaagcttct
    38221 tcaaaagaca gcgacattgc tactacagca actaaagttg aattagcaac taaagtcggt
    38281 gaagcaattg ctaaaaaagc tgctgacaaa ggcattaaag aaatcgtatt tgaccgtgga
    38341 ggatatttat atcacggacg tgttaaagca ttagctgaag cagcaagaga aagcggatta
    38401 gaattttaat ttaaaggagg gacaaataca tggctcgtag agaagaagag acgaaagaat
    38461 ttgaagaacg cgttgttaca atcaaccgtg tagcaaaagt tgtaaaaggt ggtcgtcgtt
    38521 tccgtttcac tgcactagtt gtagttggag acaaaaatgg tcgtgtaggt ttcggtactg
    38581 gtaaagctca agaggtacca gaagcaatca aaaaagctgt tgaagcagct aaaaaagatt
    38641 tagtagttgt tccacgtgtt gaaggtacaa ctccacacac aattactggc cgttacggtt
    38701 caggaagcgt atttatgaaa ccggctgcac ctggtacagg agttatcgct ggtggtcctg
    38761 ttcgtgccgt acttgaatta gcaggtatca ctgatatctt aagtaaatca ttaggatcaa
    38821 acacaccaat caacatggtt cgtgctacaa tcgatggttt acaaaacctt aaaaatgctg
    38881 aagatgttgc gaaattacgt ggcaaaacag tagaagaatt atacaattaa ggagggaaaa
    38941 ctagttatgg ctaaattaca aattaccctc actcgtagtg ttattggtcg tcctgaaaca
    39001 caacgtaaaa ctgttgaagc tttaggtctt aaaaagacta acagttcagt agttgttgaa
    39061 gataaccctg ctattcgtgg gcaaatcaac aaagttaagc acttagtaac agtagaagaa
    39121 aaataatcaa ggaggtgccg aaatgaaatt acatgagtta aaaccggcag aaggttcacg
    39181 taaagaacgc aatcgtgttg gacgtggtgt tgcgacaggt aatggtaaaa caagtggtcg
    39241 cggacacaaa ggtcaaaaag ctcgttcagg cggtggtgta agaccaggat ttgaaggtgg
    39301 tcaattacca ttattccgtc gtttaccaaa acgtggtttt actaacataa atcgtaaaga
    39361 atatgctatt gttaacttag accaacttaa taaatttgaa gatggtactg aagtaactcc
    39421 agctttatta gtagaatctg gtgttgttaa gaatgaaaaa tctggtatca aaatactagg
    39481 taatggttca cttgataaga aattgacagt gaaagctcat aaattctcag cttcagcagc
    39541 agaagctatt gatgctaaag gtggagcaca cgaggtgatc taatgattca aacccttgtg
    39601 aacttcttta gaacaaaaga ggttcgtaac aagattttct tcacactagc aatgttagta
    39661 atttttaaaa tagggactta tataccagct ccaggagtaa atcctgcagc ttttgataat
    39721 ccccaaggtt ctcaaggtgc cactgagtta ttaaatactt ttggtggcgg agccttgaaa
    39781 cgattttcta tttttgcaat gggtattgta ccctacatca ctgcatcaat cgtaatgcaa
    39841 ttattacaaa tggatattgt ccctaaattc tcagaatggg caaaacaagg tgaagtaggt
    39901 agaagaaagt taaataacgt tactcgttat ttagcaattt ctttagcatt tatccaatct
    39961 ataggtatgg cattccaatt taataattat ctcaaaggtg cgctgattat caatcagtca
    40021 attatgagtt atttattaat agcactagtt ttgacagcag gaactgcttt cttaatatgg
    40081 cttggtgatc aaatcactca gttcggtgtt ggtaatggta tttctattat catatttgcg
    40141 ggtattttat caacgttgcc agccagtcta attcaatttg gacaaactgc gttcgttggg
    40201 caagaagata catcattagc atggttgaaa gtattaggac ttttagtgtc actgatacta
    40261 ttaactgtag gtgctattta tgtacttgaa gccgttcgta aaattccgat tcaatatgct
    40321 aagaaacaaa ctgctcaaag attaggttca caggcaactt atctaccttt aaaagtgaac
    40381 tcagccggtg ttattcctgt aatctttgca atggcgttct tcttactgcc tagaacatta
    40441 acgttgttct atccagataa agaatgggca caaaacattg cgaatgctgc aaatccttca
    40501 agtaatgttg gtatggttgt atatattgta ctaattatac tattcacata cttctatgca
    40561 tttgtacaag ttaatccgga aaaaatggct gataacctta agaaacaagg tagctatgtt
    40621 ccaggcatta gacctggtga acaaaccaaa aaatatatta ctaaagtttt atatcgttta
    40681 acttttgtag gttctatctt cttagccgtt atttcaattc taccaatatt agcaactaag
    40741 tttatgggat taccacaatc aattcagatt ggtggtacaa gtttacttat cgttattggt
    40801 gtagcgattg aaacaatgaa atctttagaa gctcaagtat ctcaaaaaga atataaaggc
    40861 tttggtggta gataatttta ggagggcact tatgaatatc attttgatgg gtttacctgg
    40921 cgcaggtaaa ggaactcaag caagtgaaat tgtcaagaaa ttcccaatac cccacatttc
    40981 aactggtgac atgttcagaa aagctataaa agaagaaact gaattaggta aagaagctaa
    41041 gtcttatatg gaccgtggcg aattagttcc tgatgaagtg actgtaggta tcgttaagga
    41101 aagaatttct gaagacgatg caaaaaaagg ctttttatta gatggcttcc caagaacaat
    41161 cgagcaagct gaggcattaa ataatattat gtctgagctt gacagaaaca ttgatgctgt
    41221 catcaatatc gaagttccgg aagaagaatt aatgaaccgt cttacaggtc gtcgaatctg
    41281 tgagtcatgt ggtacaacgt atcatcttgt atttaatcct ccgaaggtcg aaggtatttg
    41341 tgatatcgat ggtggtaaat tgtatcaacg agaagatgat aatcctgaaa cggtagctaa
    41401 tcgtttgagt gttaatatta aacaatctaa gcctatttta gatttctatg atcaaaaagg
    41461 tgtattgaaa aatattgatg gttcaaaaga tattagcgac gttaccaaag atgtcattga
    41521 tattttagat catttgtaat agatcaactt ttagcggtct attttaagtg aggcatgatt
    41581 taatcatatt agatagatga gagtggcaat taacgataat taattcccgt aatttttgtt
    41641 taacttataa aattaatcac tgatagattc gtaacaataa agttgtctat tgacgattac
    41701 cttactattg caaaaagggg gaagttaatc aatggctaaa caagatgtaa ttgaattaga
    41761 aggtactgta ttagatactt taccgaacgc aatgtttaaa gtagaattag aaaatggtca
    41821 tgagatttta gctcacgtaa gtggtaaaat cagaatgaat tacattcgta ttctacctgg
    41881 cgacaaagta actgttgaga tgtctccgta cgatttaaca cgcggaagaa ttacttatcg
    41941 ttataaataa tcgtcactcc ataatatagg gaggtataaa aatgaaagta agaccatcag
    42001 taaaacctat ttgcgaaaaa tgtaaagtca ttaaacgtaa aggtaaagta atggtaattt
    42061 gtgaaaatcc aaaacacaaa caaagacaag gttaataaaa gagaggtgta aattaatatg
    42121 gcacgtattg caggagtaga tattccacgt gaaaaacgcg tagttatctc attaacttat
    42181 atatacggta tcggtacgtc aactgctcaa aaaattcttg aagaagctaa cgtatcagct
    42241 gatactcgtg tgaaagattt aactgatgac gaattaggtc gcatccgtga agttgtagac
    42301 ggttataaag tcgaaggtga cttacgtcgt gaaactaact taaatatcaa acgtttaatg
    42361 gaaatttcat cataccgtgg tatccgtcac cgtcgtggtt taccagttcg tggtcaaaaa
    42421 acgaaaaaca acgcgcgtac tcgtaaagga ccagttaaaa cggtagctaa caagaaaaaa
    42481 taataggtaa aggaggcaaa ttttaaatgg cacgtaaaca agtatctcgt aaacgtagag
    42541 tgaaaaagaa tattgaaaat ggtgtagcac acatccgttc aacattcaac aacactattg
    42601 taactatcac tgatgagttc ggtaatgctt tatcatggtc atcagctggt gcattaggat
    42661 tcaaaggatc taaaaaatca acaccatttg cagcacaaat ggcttctgaa actgcatcta
    42721 aatcagctat ggagcatggt ttaaaaacag ttgaagtaac agttaaagga cctggtccag
    42781 gtcgtgaatc agctattcgt gcattacaat ctgcaggttt agaagtaact gcgatcagag
    42841 acgttactcc agtacctcat aacggttgtc gtccaccaaa acgtcgtcgt gtataattta
    42901 tgatggtatt gttacaggtc actgagcaaa cattttaaat taagtcgacg tatataagga
    42961 ggatatttaa atgatagaaa tcgaaaaacc tagaattgag acaattgaaa ttagtgaaga
    43021 tgctaaattc ggtaagttcg ttgttgaacc actagaacgt ggctacggta ctacactagg
    43081 aaactcctta cgtcgtatcc tactatcttc attaccaggt gcagccgtta agtatattga
    43141 aattgaggga gttttacatg aattctcagc agtagacaat gtagttgaag atgtttctac
    43201 aattattatg aacattaaac aattagcatt gaaaatttac tctgaagaag ataaaacttt
    43261 agaaattgat gtacgtgatg aaggcgaagt aacagcaagc gacattacac atgatagtga
    43321 tgttgaaatt ttaaacccag agcttaaaat tgcaacagta tctaaaggtg gtcacttaaa
    43381 aattcgtcta gttgctaaca agggtagagg ttacgcatta gcagaacaaa ataatactag
    43441 tgatttacca attggtgtaa tccctgttga ttcattgtat tcacctgttg aacgtgtgaa
    43501 ctatactgtt gaaaatacac gtgtaggtca aagcagtgat tttgataaat taacattgga
    43561 tgtttggact aatggttcaa tcacaccaca agaatcagtt tcattagcag caaaaataat
    43621 gactgaacac ttgaatatct tcgttggtct tactgatgaa gcgcaaaacg ctgaaatcat
    43681 gattgaaaaa gaagaagatc aaaaagaaaa agtattagaa atgtctattg aagaattaga
    43741 cttatctgta cgttcatata actgcttaaa acgcgcagga atcaattctg ttcaagagtt
    43801 agctgacaaa tctgaagctg acatgatgaa agtgcgtaat ttaggtcgta aatctttaga
    43861 agaagttaaa tacaaattag aagatttagg attaggatta agaaaagaag attgataaag
    43921 gaggttaact catgggttac agaaaattag gtcgtacttc tgatcaacgt aaagctatgt
    43981 tacgtgactt agctacatca cttattatta gtgaacgtat tgaaactaca gaagctcgtg
    44041 caaaagaagt tcgcagtgtt gttgagaaat taatcacttt aggtaaaaaa ggagatttag
    44101 cttctcgtcg taatgcagct aaaactttac gtaatgttga aatcttaaac gaagatgaaa
    44161 ctacacaaac tgcacttcaa aaattatttg gtgaaatcgc agagcgttac acagaacgtc
    44221 aaggtggtta cactcgtatc cttaaacaag gccctcgtcg cggtgacggt gctgaatcag
    44281 taattatcga attagtataa gaatttatat aaatacacta actactttta tataaagcaa
    44341 atgagtgcaa cgataatgtt tgccacatac aaatattgtc tagctcagag taccccatca
    44401 actaaataaa gatttaaagc gtgaactcaa caaacttatg atggggtgcg cgctttttta
    44461 ttgaataaga tatcggactt atgaacagaa atgtttttaa gtccgatttc tttatatcta
    44521 cttttttgag tgcgaatcta aaaatatgat caagctagtt tgatcaattt cactagaact
    44581 gaatgaagtg aaagtattat cgttgaacca aacgcgacca cccctatatt agtaaatcat
    44641 ttattttatt aacgtttata cataattgtt agagaggaat aaatgtcctt atcattagtt
    44701 gttaaacaac actttaaaga ctagaaatga gttagaaaat actagtaata tatagcaaac
    44761 ccagtcaatg tcatatacag cgatttataa atattgtaaa atatgataga tacacgaatc
    44821 gtaaaggaga gagacaagtg gaggataaga attcagttat tgtatttaaa aatgtttcat
    44881 ttcaatatca aagtgatgca tccttcacat tgaaagatgt ttcttttaat atacctaaag
    44941 gtcagtggac atctattgtt ggtcataacg gttctggaaa atctacaatt gccaagttaa
    45001 tgattggcat agagaaagtt aaatctggag aaatttttta taataatcaa gctataactg
    45061 atgataattt tgaaaagtta agaaaagaca taggaattgt atttcagaat ccggataatc
    45121 aatttgttgg ttcaattgta aaatacgatg tggcatttgg actcgaaaat catgcggttc
    45181 cacatgacga aatgcataga agagtcagcg aagcacttaa acaagttgat atgttagaac
    45241 gtgcagatta tgaacctaat gcattatcgg ggggacagaa gcagcgtgtg gctatagcaa
    45301 gtgtattagc acttaacccc tctgtcatta tattagatga ggcgacttct atgttagatc
    45361 ctgatgcacg tcaaaattta ttggatttag tgagaaaagt taaatcagaa cataatatta
    45421 caatcatttc tattacgcat gatttatctg aggcgatgga agcagatcat gttatcgtta
    45481 tgaataaagg gactgtctat aaagaaggca cagcgactga aattttcgac catgcagaag
    45541 agttaacaag aataggtcta gatttgccat tcccaatcaa aataaatcaa atgctgggac
    45601 accaaacatc attcttaact tatgaagggc tggtggatca actatgacta tacggtttga
    45661 caatgtaagt tatacctatc aaaaagggac accatatcag catcaagcta ttcatgatgt
    45721 taatacagaa tttgaacaag gtaaatatta cgccatcgtt ggacaaacgg gtagtggtaa
    45781 atcaacgttg atacaaaata ttaatgcgct gttaaagccg actactggga cagttacagt
    45841 tgatgacatt actattacac ataagaccaa agataaatat attagacctg taagaaaaag
    45901 aattggaatg gtatttcaat ttcccgaatc tcaattattt gaggacacag tagagcgtga
    45961 aatgatattt ggacctaaaa actttaaaat gaatttagat gaagccaaaa actatgccca
    46021 tcgtctgttg atggatttag gcttttcaag agatgtaatg tcacaatcac catttcaaat
    46081 gtcaggtgga caaatgcgta aaatagcgat tgtatcgata ttggcaatga atcctgatat
    46141 tatcgtggtt gatgaaccta cagcaggact tgatccacaa agtaaacgac aagtaatgag
    46201 attactaaag tcactacaaa cagatgaaaa taaggcaatt atcctaattt cacatgatat
    46261 gaatgaagtc gcgcgttatg cagatgaagt catcgttatg aaagaaggta gtatagtgtc
    46321 gcaaacatca ccaaaagagc tcttcaaaga taaaaaaaaa ttggcggatt ggcatattgg
    46381 tttgccagaa attgttcagt tacaatatga ctttgaacaa aaatatcaaa caaaattaaa
    46441 agatattgcc ttaactgaag aagcatttgt aagcttgtat aaggagtggc aacatgaaaa
    46501 ataaattgat tatagggcga tatttaccaa ttaattcttt tgttcatcat cttgatccaa
    46561 gagcaaagtt aatgtttgtt tttcttttta ttatattaat atttttctgt cattcaccat
    46621 taacatatct ttgggtgttt gcacttatct tattcattat gagattagca aaaattcaat
    46681 tatggttcct aatcaaaggt ttaacaccaa tatttttctt tttaatcttc acattaatga
    46741 tgcatatatt tttaactaaa ggtggatatg tattagttga atggcatggc atcacgattg
    46801 aaactaatgg tattttagaa gggctatata tatcattgcg tttaattggg attgtgatga
    46861 ttgcaacaat tatgacacta tctacaagtc caattgattt aacagatgcg tttgaaagat
    46921 tacttgcacc actaaagatg tttaaattac cagttcatca attaagtatg ataatgtcca
    46981 ttgcgttacg attcatcccg acgttaatgg atgagttaga taaaattatt ttggcgcaaa
    47041 agtcgcgtgg ttctgaaata agttcaggga acattgcaac acgtattaaa tcatttattc
    47101 cattactagt gccactattc atctcagctt tccaacgcgc cgaagaatta gcggtcgcaa
    47161 tggaagttag gggttatgat gccaatgtta agagaacgag ctacagacag cttaaatggc
    47221 aattgagaga tacgatatct ttaaccatga ttatcccaat tgcaattatt ttattcgtat
    47281 taaaatattc aggagtgtaa attcatgcgt atattagtag aaattgcgta tcaaggaaat
    47341 aattttctag gctttcaaat tcaacagaat ggacgtacgg tacagcaaca atttgaaaag
    47401 ctattacaac gcatgcataa aagacatgtg agaatccatc cttcaagtag gactgataga
    47461 ggtgtacatg cgatacagca gtactttcat ttcgacacag agctgaatat acctatgtca
    47521 caatggcaat atgcaatgaa ccgaacgtta ccagatgata tttatgtcaa taatgtagtt
    47581 acagtcgatg acgattttca ttgtcgttac gattgtgtcg gtaaacgcta tcgatataaa
    47641 gtatatcaag cacaacaccg cgatccattt caaagtggtt tgaaaacatt tattcctgaa
    47701 acgttggatt tagacaaaat gaacagagcg gcgcaacaat tcataggtac acatgatttt
    47761 acggggtttt gttcgcaaaa aactgaagta gaaagcaaag ttagaacatt ataccaaagt
    47821 gaaatcgtaa agacagatga tggctttgat tatattgtca ctggatctgg atttttatat
    47881 aacatggtgc gtgtcttagt tgcattttta atagaagttg gaaaagggcg acatgaaatt
    47941 tctgatgtgc cgaagctact tgaatcaaag aatcgtaaga atgttccttt cactgcaccg
    48001 gctgaaggac tatatttaga gaagatttat ttagatgaaa atgagttatt aaaagacttt
    48061 ggcaacgata taaaaataca tcgcaaaaaa tcattacaaa atgactgatt gccattgaca
    48121 aaaagcttgt gaaattataa gattattaac ggtattgttt tatatccacc ccacgataag
    48181 ccccggaaac ttattgtgtt acaagatata taagcagaaa cgaacaacag ttaacaaaat
    48241 aaatgaaatt aaacgtttta aaaatgaaac aaatgaaatc atctattagg ttatgaaact
    48301 gtttatagct tgaatagaag catttatttt ttaggaggac aattattatg cgtcaaacat
    48361 ttatggcaaa tgaatcaaac attgagcgca aatggtatgt tatcgatgct gaaggccaaa
    48421 cattaggtcg tttatcatca gaagtagcat ctatcttacg cggtaaaaat aaagtaactt
    48481 acacaccaca cgttgatact ggtgattatg taatcgttat taatgcatca aaaatcgaat
    48541 ttactggtaa caaagaaact gacaaagttt actaccgtca ctcaaatcat ccaggtggta
    48601 tcaaatcaat cactgctggt gaattaagaa gaactaaccc agaacgttta attgaaaact
    48661 caattaaagg tatgttacca agcactcgtt taggcgaaaa acaaggtaaa aaattatttg
    48721 tatatggtgg cgctgaacat ccacacgctg cacaacaacc agaaaactac gaattacgtg
    48781 gttaattaga aggaggaaat gactttggca caagttgaat atagaggcac aggccgtcgt
    48841 aaaaactcag tagcacgtgt acgtttagta ccaggtgaag gtaacatcac agttaataac
    48901 cgtgacgtac gcgaatactt accattcgaa tcattaattt tagacttaaa ccaaccattt
    48961 gatgtaactg aaactaaagg taactatgat gttttagtta acgttcatgg tggtggtttc
    49021 actggacaag ctcaagctat ccgtcacgga atcgctcgtg cattattaga agcagatcct
    49081 gaatacagag gttctttaaa acgcgctgga ttacttactc gtgacccacg tatgaaagaa
    49141 cgtaaaaaac caggtcttaa agcagctcgt cgttcacctc aattctcaaa acgttaattg
    49201 tcggacgata tatacaaaac acctcgatat tatgtcgagg tgtttttttg cgtttgtgtg
    49261 ttttaaaatt atttggctct atatcaaatt ggactgatgc attcaatatc ggaagttagg
    49321 caactaaaca ttgcttaact tcctttttat tttttggagc gtaaagtttt gaacctaaat
    49381 tccaagagaa ttaataattt ttttcctttc tttttcgagg tcatcaaaag tttgtatatt
    49441 ctttttaact atgttactta tatattcaat aattattaat ttaatccaat ttaatagctt
    49501 gtacacatcc tcataattat catataaatc aaatatactt ttaccattgt gaataatttc
    49561 agttcttaga ttttcactaa tatttcttag atactcactg cacttatgat actgatgttt
    49621 agaataagaa ataaaaggaa ggattttaga tttagttttt ttaaagttta aatattcacg
    49681 acttgatagc atttctaatg tacttaaaag ataaacaaat gatgtattta aattattcat
    49741 gtacattgat tcagaaactc tgtggatagc ttctctgaaa agtaaattaa tttcatttga
    49801 agtaacataa agacaattat ataatttatc ttcataaata ttagaagata agtcaattgg
    49861 atataatcct attccttctc gaatcataaa catgactttt ccattaattg ttctaagttt
    49921 gtggtcagtc aattgttcag ctacttgcca accatttgag gtaatacctg gtatacctgg
    49981 taattgttca ggaacaccaa aattattttc gtttattctt ataatatcta gagttctgtc
    50041 ggctttttga cttaacttat taataaaata ataattttgg tctaccgtgg taggttcaaa
    50101 gaaatcgtcc ttaaaaataa ctagtgcatc ttcttttaat tgcgaagtag ataaaataga
    50161 taaaaactct tttttgttaa acattgatat tagtgaaaag tctgtatgaa aatgacctga
    50221 ttcaattact tttaaagatg gggttaagat aacattgcca atttgtaaag gtgactcaat
    50281 aactatataa gctaatggta agatataaat actctttttc attataaaat cctcctaaaa
    50341 attaatatgt ttttgaaatt catctgccaa tttttctcta gatgattttg taatgtgttt
    50401 ataaatgtcc atagtcgtct ttatatcact atgacctaat ctagttttac ttctttaagt
    50461 tgttgcacct gattcgaata atagtgaagc acgagtatgc ctgaagctat gaacgtgtat
    50521 cttatgaaga tttgaatatc atttaaagaa tacctctaat tcgtcattag gcatcgatac
    50581 acgcatgtac ttcatttagt ctactatgta tggtatgttg aaaagatatg ttgctcttta
    50641 tcactagaga ctgaaaatcc atattcttca ttttgtagat tttgttcttc tttccattgt
    50701 aaaagtttat ttatagtttg aataccaata tctatccatc tttgatactc acattttttt
    50761 agtggttgca atacatgttt atttttcact ggaaattata atttaataat gtacacttat
    50821 gattgtttaa acatgtaaaa tttttaaaaa cctagagata attttattga ggcgaacaac
    50881 aatgaaatta tctttagaca taaatatgga tttttaagtt attactctta cagatttacc
    50941 aaaattaaaa attgttaagc agaacttaat catgaaataa acaaaagtga aatagcaaga
    51001 catatggggg atgatagaag aacagttgat aaataattaa atggttttga gccgaccaag
    51061 aagaggaacc gtcagtctat tattgacaag tattatccaa tcatccaaaa gttactttca
    51121 cactagtgaa taatagttct actataatgg tgtattttga caatatttga aggttaaact
    51181 tagattaacc tgtgtctatt ctgcatttag agcttatgtc cttaagcatg ttgtatttaa
    51241 tcgttatttt atgaaaggtt atcaacagat gtcgcctaaa ggtacaacga gaatcgagac
    51301 aaaaaccggt catcaagcac agtttgactg gaaagaaggc attaacttta aaacgaatga
    51361 taatcaaata gtttcactaa atataggcgt gttactactt tcttactccc gttttgtaat
    51421 catgaaagtg acaatgaata aatcgagtga tgttttattt aatttattta cacaagcgtt
    51481 tgagctaatg tgagatgtgc ctgatgtact tgtaactgat agtattatat ttagaagagg
    51541 ttcctaagtt tatttctaat cttaaagagc gactgaacta ctcagttcat gtgagtacag
    51601 gtaaaatgcc tattattgcc ttagaaaaag aaaaagttct tacaatcact accgaatgtg
    51661 aatgtaagaa actcatataa agtgaaacat aaatatttga aagtcaaccg ctctaatatg
    51721 attacatata agtccaatca atattcagca tcagctgaat attgtgggaa aacagttgaa
    51781 gttcaagttt atgatcaaaa acaacacgtt taatataaga ctaaattgat ttgtgaacat
    51841 ctcatcacac aacgtaaatt aaattatcaa aaagaacatt atttagaatc actgccatcc
    51901 tcttttggga atagagaaaa ggatgatatt aatcagatta cgatagataa tttaaatgcg
    51961 attggatagt tttatgatga ataattcaac gaattataag cgcttaaaag caaatttaga
    52021 atatttgaaa atgaatcaga tgattaacca tcttgatgat gttatcgatt ttataaacac
    52081 aacctgtcat tcatagacac attaattaaa ttaagcgatt acaaaatcaa aattaaggag
    52141 aaaaatttga ttgaatcgat ggtaaaggtt atggcgttac cgtttaaaaa gaaatatcag
    52201 cctttgactt taattttcaa ccgagcatca atcaacaaga tgttttggat tttacggatt
    52261 tacgttttat aggaaaatat gaaaacatag tctttttaga ctcaaatgtc gttagtaaaa
    52321 atagaataag tacttacttt attaagtgtc atcatttgaa agagaattta agaaaagcaa
    52381 aacttgagaa cagcttagaa aatagattga agcactatag caagtataag ttattaatca
    52441 ttgatgagat tgggtactta cctattggaa gtgaagctgc caaaatattc ttccaaatta
    52501 atagatttaa ggtatgagaa gaaaagcaca atatttacca caaatatcaa tttcaactta
    52561 taaaatgaaa tatttgatga tcccaaaatc gcaaatgcga ttttggatag gatattgcat
    52621 cattcaagtg tagtaaaaat cacaggaaaa tcgtatagat taaaaaatca ttcacctaaa
    52681 aagaaaatta cttagcaaac aattttgtac atttctatac aatcatttat gtagatttta
    52741 atattgacat ttacatccaa ctaaatgtag acgattcaca gacaaccgat ataattaatt
    52801 tgtccatcca ttttaggtgg cattttatca tgaggagtat agttttgatt gcaaaaaaac
    52861 aaatattaga acatttatcg tgaagaaaaa atgatatact tgaagaaaag tataaatata
    52921 aaaagtgaag atatttataa gaggagaaag ctaatggcta atacaaaaca aatccattaa
    52981 atcaacaaga acttagaaat gcaatctagt caggtccatt tataacaaaa gcaaagtatg
    53041 aattttctaa ttctatgaat gctaatcagc aaaaaatggc aaagttatat taaaggaatt
    53101 ccaaatagat aagaaatatt agaagaagct ctaaatgggg gaagtaaagg tgatattaat
    53161 ggatacatgt caagacatca taatgatata aatgatttaa aaacatactt taactcagtt
    53221 atagattgga tatcgagcat ttttattaat gtagaaaaag aaatgcgggg attagaatag
    53281 agaagtttat atgaaacata tcataacaac tcttaaaatc cttcagtatt agaatataaa
    53341 cttttaagtt tatatgaaga tagtgatgtt tcaaggaagc taggaatttt tgagtattta
    53401 ttaagcggag aaaaattaga atttataaaa taactatcaa ttagagcttt cactgaagcg
    53461 aataaaaagt ctaaatatca agagcaaact aataatgctc gaaaaagtga agcttcaaat
    53521 tgtcctattt gtaatacaga tttacaatat gatcaccaaa cacatatatg gaattataaa
    53581 gatatggtag gagatcatat tataccatgg agtaaaggtg gaaaaacaga gcgtggaaac
    53641 ttacagatgc tttataaaca tcataatagt ctaaaatcca attactagta ataaattaat
    53701 tatatattat attcgaaaaa ttattttgtc atgctgttct taatataata cactgtgtgg
    53761 tgagtatttg aaacaaaatg tagaatttaa tcaagcggtt attaagttta ataaaagaaa
    53821 taaaataaat aaatcatcta atgatgagta tataaaaaaa tttagaaata aattcggaaa
    53881 atttctaagt caaagttttt tgaatagtaa taatgtaata aagcaagaga ttataaaaat
    53941 tattaaagat gaatattatt attatgatca agaaaatacg aagaaatatt taataaagtt
    54001 ttgtcaagat cttatagaac atataaaaga gcacagaaat caaatcaatg attgtcactt
    54061 tacaaatata ttaaataaag atgcagaaaa aactaatagt tcaagtatct taacttcatt
    54121 atttttaact gcaaacaata taccaaataa tctatcatct aatttttcta aagcagtgga
    54181 atattatttt gcaaaaaaca aggaaatata tggagatgga tatgaaaagt atttagacga
    54241 gtattttaga aatgttttag gcgaaaaaag ttatttaatt ttgatagatg atttttcagg
    54301 gacaggaaaa tcaatcagcg actttattga tgcaataaaa aagtatatac taacattaaa
    54361 aatagagatt attatatttt gcatacatat aaccgaagat gcagaaaaaa aataatggat
    54421 acttcaataa aaaacggtat tgagataaaa atagcttttg tacaaaaaac agagaaatat
    54481 tttataaata ataaagagct agagaaaaaa ttttatgaat ttgaaaagga tattgtaaat
    54541 ccaggtaagt actacaactt aggctataaa aatactcaag cattagtatc aaattttaga
    54601 aatactccaa ataatacact gagccttttt tggcatgaga atgatcagtg gaaaccttta
    54661 tttaaaagaa aagctaaaaa tgattttagt aataaatgga aagaaaaggt tcatattatt
    54721 agatggtttc tggcatataa aaaagttcct aaaattttgg tagataaaat tatagcaata
    54781 atgtatgtta aaaatcatgc tgatatgaaa tcgaaatttt tagaaattga gatt
//
LOCUS       DAPDIM010000010        52335 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000010 DAPDIM010000000
VERSION     DAPDIM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 52335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52335
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.010"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            219..2852
                     /gene="clfB"
                     /locus_tag="RFE25_000659"
     CDS             219..2852
                     /gene="clfB"
                     /locus_tag="RFE25_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin clumping factor ClfB"
                     /protein_id="HDU2815758.1"
                     /translation="MKKRIDYLSNKQNKYSIRRFTVGTTSVIVGATILFGIGNHQAQA
                     SEQSNDTTQSSKNNASADSEKNNMIETPQLNTTANDTSDISANTNSANVDSTTKPMST
                     QTSNTTTTEPASTNETPQPTAIKNQATAAKMQDQTVPQEANSQVDNKTTNDANSIATN
                     SELKNSQTLDLPQSSPQTISNAQGTSKPSVRTRAVRSLAVAEPVVNAADAKGTNVNDK
                     VTASNFKLEKTTFDPNQSGNTFMAANFTVTDKVKSGDYFTAKLPDSLTGNGDVDYSNS
                     NNTMPIADIKSTNGDVVAKATYDILTKTYTFVFTDYVNNKENINGQFSLPLFTDRAKA
                     PKSGTYDANINIADEMFNNKITYNYSSPIAGIDKPNGANISSQIIGVDTASGQNTYKQ
                     TVFVNPKQRVLGNTWVYIKGYQDKIEESSGKVSATDTKLRIFEVNDTSKLSDSYYADP
                     NDSNLKEVTDQFKNRIYYEHPNVASIKFGDITKTYVVLVEGHYDNTGKNLKTQVIQEN
                     VDPVTNRDYSIFGWNNENVVRYGGGSADGDSAVNPKDPTPGPPVDPEPSPDPEPEPTP
                     DPEPSPDPEPEPSPDPDPDSDSDSDSGSDSDSGSDSDSESDSDSDSDSDSDSDSDSES
                     DSDSESDSDSDSDSDSDSDSDSESDSDSDSDSDSDSDSDSESDSDSESDSESDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSRVTPPNNEQKAPSNPKGEVNHSNKVSKQHKTDALPETGDKSENTNATLFGAM
                     MALLGSLLLFRKRKQDHKEKA"
     gene            2968..3729
                     /locus_tag="RFE25_000660"
     CDS             2968..3729
                     /locus_tag="RFE25_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDU2815759.1"
                     /translation="MAYISLNYHSPTIGMHQNLTVILPEDQSFFNNDITAKPLKTLML
                     LHGLSSDETTYMRYTSIERYANEHKLGVIMPNVDHSAYANMAYGHSYYDYILEVYDYV
                     HQIFPLSKKRDDNFIAGHSMGGYGTIKFALTQGDKFAKAVPLSAVFEAQNLMDLEWND
                     FSKEAIIGNLSSVKGTEHDPYYLLDKAVAEDKQIPKLLIMCGKQDFLYQDNLDFIDYL
                     SRKNVPYQFEDGPGDHDYAYWDQAIKRAITWMVND"
     gene            3974..4429
                     /locus_tag="RFE25_000661"
     CDS             3974..4429
                     /locus_tag="RFE25_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDU2815760.1"
                     /translation="MSTNKNDYEHMLFYFAYKTFITTADEIIEKYGMSRQHHRFLFFI
                     NKLPGITIKSLLEILEISKQGSHATLQKLKEQGLIIEKVLETDRRVKKLYSTDKGDQL
                     IAELNKAQDELLQNIYQQVGSDWYDVMEALAKGRPGFDFIKHLKDEKES"
     gene            complement(4532..4642)
                     /locus_tag="RFE25_000662"
                     /pseudo
     CDS             complement(4532..4642)
                     /locus_tag="RFE25_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501411.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4712..6136)
                     /locus_tag="RFE25_000663"
     CDS             complement(4712..6136)
                     /locus_tag="RFE25_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HDU2815761.1"
                     /translation="MLSVKKATKFAVANLIIVSTVFSSVTPAIAQSDKSSKDESFAVG
                     NTKNPKNVIFLVGDGMGPSFNTAYRYYKNDSHAKEMTPTAFDSYLKGTNRTYSNDPKQ
                     NITDSAAGGTAFSSGHKTYNGAVGVDSNKQKVKTVLERAKEKGKSTGLVSTAELTDAT
                     PAAYAAHVTSRDDKNEIAKQFYKDKINGKHKVDVLLGGGAKYFGKSNGNLDKKFKKDG
                     YDLATNSKDLSKSDKDKVLGLFADKNMPLAIDASKDEPSLADMQQSALSKLERNKKGF
                     FLMVEGASIDKSAHSNDITGVMSEMEGFEKAFDDAIQYAKKHKDTLVVATADHSTGGL
                     TIGKDKGYEWNPQPIKSMKHSGSYMTEKMAKGEDPEKVINEGYGFEFSQDDMKKVKKE
                     NKKLQKLLKKEKDEKSADVEKQTKALQHAIQKPVNDKSYTGWTSDGHTGEDVNTYAYG
                     PRSESFSGNIENTESAKIIFDIFK"
     gene            6334..6534
                     /locus_tag="RFE25_000664"
     CDS             6334..6534
                     /locus_tag="RFE25_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815762.1"
                     /translation="MILVMLSPLLIIFFIVLSILEERKRTKKKQLEKEKANTLNQNTN
                     DTESSNQEPSLQQTKEQKDNKG"
     gene            6560..7225
                     /gene="nsaR"
                     /locus_tag="RFE25_000665"
     CDS             6560..7225
                     /gene="nsaR"
                     /locus_tag="RFE25_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nisin susceptibility-associated two-component
                     system response regulator NsaR"
                     /protein_id="HDU2815763.1"
                     /translation="MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQ
                     PQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSRIDNMDQIMAIQMGGDDFIEKPF
                     NLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
                     LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVG
                     YKV"
     gene            7236..8123
                     /gene="nsaS"
                     /locus_tag="RFE25_000666"
     CDS             7236..8123
                     /gene="nsaS"
                     /locus_tag="RFE25_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nisin susceptibility-associated two-component
                     system sensor histidine kinase NsaS"
                     /protein_id="HDU2815764.1"
                     /translation="MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILL
                     LLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNEQIEYKNDVESYFLTWVHQMKTP
                     ITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
                     PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFD
                     EQSNQLHVKDNGIGISEADLPKIFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPV
                     SVVSKQNEGTTFTIQFPDE"
     gene            8231..8986
                     /locus_tag="RFE25_000667"
     CDS             8231..8986
                     /locus_tag="RFE25_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815765.1"
                     /translation="MLLEVKHVKKVYGKGLNATTALNQMNLSVGAGEFVAIMGESGSG
                     KSTLLNLIASFDGLTEGDIIVDGAHLNNMKNKSKALYRQQMVGFVFQDFNLLPTMTNK
                     ENIMMPLILAGAKRKDIEQRVHQLAVQLHLEGFLNKYPSEISGGQKQRIAIARALVTK
                     PTILLADEPTGALDSKTSKALMMLFQEIHQLEQTILMVTHSNIDASYAERVIFIKDGR
                     LYHEIYRGEESQLAFQQRITDSLALVNGGSVNI"
     gene            8983..10983
                     /locus_tag="RFE25_000668"
     CDS             8983..10983
                     /locus_tag="RFE25_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815766.1"
                     /translation="MKLRLLWHIVRRQFITQRLVIIPFILAVSVLFMIEYTLVSIGLN
                     SYIKQKNDFLVPFIIIANFFMALLTFIFIFYANHFMMSQRRKEFSIFMTLGMTKKSMR
                     LIVVMETILQFVIISVVSIAGGYLLGAIFFLFIQKIMGSEVATLRYYPFDSVAMFITL
                     IIIAVLMGMLLIFNLFSINFQRPITYQHRSDSSVISRWLRYVLIVIGSAALYLGYFIA
                     LQQDTTFGAFFKIWIVIGLVIIGTYAFFVGISEIIISILQQVSKVYYHPRYFFVVVGM
                     RVRLKMNAVSLATITLLCTFLIVTLTMTLTTYRDMNHTITKLITNDYDLSFSDNSKSQ
                     IERQQTIENIKRDIQGSVNAKDFKVYETTLFRASLEKNRAYYKLKQASDDIPIDFIGN
                     EGAIFSRQSVMITAFTAQDYNRYHQNKLHLDNQSIGMITNVPIFKKQSKVGLNNEVFK
                     VKQLDAHALNLMMIQDSMVLIVKDNNQLQKVKGFYAHEQKNSTISINFNVFGKTKLTT
                     SQIQKLSKKYDASINSKSEMLMVWDRLTGGLIFVGGVVSIVLVIGIFLMMYYKQVSEA
                     YANQHNYDIMKKLGLDNGRIAKITRNQMTFLFAIPITVALIHTLISSNIVYTLLNMIG
                     INNHHIFLTSYVLAVIIISFLYMAMYKITSYIYAKVIHQQRN"
     gene            11642..11755
                     /locus_tag="RFE25_000669"
                     /pseudo
     CDS             11642..11755
                     /locus_tag="RFE25_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501402.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12137..12397
                     /locus_tag="RFE25_000670"
     CDS             12137..12397
                     /locus_tag="RFE25_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815767.1"
                     /translation="MIIMRGYNERYCSWTNTAIQCDYFNKVRQVKKDGKSDRLSNNIN
                     SNIIYRVLEKCITLYNVCSRCKRALILSEHSKKNIFNIKKAV"
     gene            12407..12904
                     /locus_tag="RFE25_000671"
     CDS             12407..12904
                     /locus_tag="RFE25_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDU2815768.1"
                     /translation="MNNRNVYDIEVSDYKGLTYKLEAFRGKVILVVNTATECIYSEQL
                     KKLETLFQKYKDRGFVVLSFPNNNFDNRQPGSNEEILKISREKFGVTFPVLAKISVNG
                     NDEHPLFTHLKNEQPGIFGSPIKWNFTKFIIDRQGNVVNRFLPMEDPLDISTNIEILL
                     QESSS"
     gene            complement(13012..13104)
                     /locus_tag="RFE25_000672"
     CDS             complement(13012..13104)
                     /locus_tag="RFE25_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815769.1"
                     /translation="MSVINAYSNASLLFFIYLLFIMYQISLSVK"
     gene            13298..15178
                     /locus_tag="RFE25_000673"
     CDS             13298..15178
                     /locus_tag="RFE25_000673"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     flavoprotein subunit"
                     /protein_id="HDU2815770.1"
                     /translation="MKLNTSNSPFTEKQVTEINNLLQTLTESQQQWLSGFLLANSNDT
                     TSDSNQQQLETEVWQQSQISEEQATSTTYMLQNKEPHIEANQRHVTVLYGSESGNAMR
                     LAEIFSERLSDIGHQVVLMSMDEYDTTNIAQLEDLFIITSTHGEGEPPDNAWDFFEFL
                     EDDNAPNLNHVRYSVLALGDQTYEFFCQAGKDVDALLENLGAERICKRVDCDIDYEED
                     AEKWMADIINMIDTTSEGIQSESVISESIKSAKEKKYSKLNPYQAEVLANINLNGTDS
                     NKETRHIEFLLDDFSESYEPGDCIVALPQNDPELVEKLISMLGWDPQSPVPINDRGDT
                     VPIVEALTSHFEFTKLTLPLLKNADIYFDNEELSERIQDESWAREYVINRDFIDLITD
                     FPTIELQPENMYQILRKLPPREYSISSSFMATPDEVHITVGTVRYQAHGRERKGVCSV
                     HFAERIKPGDIVPIYLKKNPNFKFPMKQDIPVIMIGPGTGIAPFRAYLQEREELGMTG
                     KTWLFFGDQHRSSDFLYEEEIEEWLENGNLTRVDLAFSRDQEHKEYVQHRIMEESERF
                     NEWIEQGAAIYICGDEKCMAKDVHQAIKDVLVKERHISQEEAELLLRQMKQQQRYQRD
                     VY"
     gene            15241..15846
                     /locus_tag="RFE25_000674"
     CDS             15241..15846
                     /locus_tag="RFE25_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HDU2815771.1"
                     /translation="MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTI
                     TEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATNEPRVNEAVKQALPEHALFNNVG
                     DASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
                     QKIKVLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVR"
     gene            15922..16017
                     /locus_tag="RFE25_000675"
     CDS             15922..16017
                     /locus_tag="RFE25_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815772.1"
                     /translation="MGGFVNSLIMKDLSDNDMRFKYEYYNREKDT"
     gene            16339..17709
                     /locus_tag="RFE25_000676"
     CDS             16339..17709
                     /locus_tag="RFE25_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HDU2815773.1"
                     /translation="MNSDNMWLTVMGLIIIISIVGLLIAKKINPVVGMTIIPCLGAMI
                     LGYSVTDLVGFFAKGLDQVINVVIMFIFAIIFFGIMNDSGLFKPLVKRLILMTRGNVV
                     IVCAMTALIGTIAQLDGAGAVTFLLSIPALLPLYKALNMNKYLLILLLALSAAIMNMV
                     PWGGPMARVAAVLKAKSVNELWYGLIPIQIIGFILVMLFAVYLGFKEQKRIKKAIERN
                     ELPQTQDIDVHKLVEVYERDQDVRFPVKGRARTKSWIKWVNTALTLAVILSMLINIAP
                     PEFAFMIGVSLALVINFKSVDEQMERLRAHAPNALMMAAVIIAAGMFLGVLNETGMLK
                     AIATNLIKVIPAEVGPYLHIIVGLLGVPLDLLTSTDAYYFAVLPIVEQTAGQFGVPSV
                     STAYSMVIGNIIGTFVSPFSPALWLAIGLAEANMGTYIKYAFFWIWGFAIVMLVIAML
                     MGIVTI"
     gene            17899..19749
                     /gene="nrdD"
                     /locus_tag="RFE25_000677"
     CDS             17899..19749
                     /gene="nrdD"
                     /locus_tag="RFE25_000677"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDU2815774.1"
                     /translation="MNQIEEALTGLISKDPAIVNENANKDSDTFSTMRDLTAGIVSKS
                     YALNYLLPKHVADAHQRGDIHFHDLDYHPFQPLTNCCLIDAKNMLHNGFEIGNANVTS
                     PKSIQTASAQLVQIIANVSSSQYGGCTVDRVDELLSTYARHNEEQHRNIAKQFVKESE
                     IDRYVDQQVTKDINDAIESLEYEINTLYTSNGQTPFVTLGFGLGTDHLSRKIQQAILN
                     TRIKGLGKDRTTAIFPKLVFSIKKGTNFSPQDPNYDIKQLALKCSTKRMYPDILNYDK
                     LVEILGDFKAPMGCRSFLPSWKDAEGHFENNGRCNLGVVTLNLPRMALESAGNMTKFW
                     EIFYERIDVLHDALLYRINRLKDAVPNNAPILYKSGAFNYKLKETDDVAELFKNKRAT
                     ISMGYIGLYETATVFYGPDWETSQEAKAFTLEILKEMKRYQTKWTELYDIWFSIYSTP
                     SESLTDRFCRLDQERFGDIKDITDKGYYQNSFHYDVRKDVTPFEKLDFEKDYPYYASG
                     GFIHYCEYPKLQHNLKALEAVWDYSYDKVGYLGTNIPIDHCYECDYDGDFEATEKGFK
                     CPNCGNDNPKTVDVVKRTCGYLGNPVQRPVIKGRHKEICARVKHMKAPKE"
     gene            19746..20282
                     /gene="nrdG"
                     /locus_tag="RFE25_000678"
     CDS             19746..20282
                     /gene="nrdG"
                     /locus_tag="RFE25_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDU2815775.1"
                     /translation="MTLLDIKQGQGYIAKIESNSFVDGEGVRCSVYVSGCPFNCVGCY
                     NKASQKFRYGEKYTDEILAEILDDCDHDYISGLSLLGGEPFCNLDITLNLVKAFRARF
                     GNTKTIWVWTGFLYEYLANDCTERRELLSYIDVLVDGLFIQHLFKPDLPYKGSLNQRI
                     IDVQQSLSHARMIEYIVS"
     gene            20382..20492
                     /locus_tag="RFE25_000679"
     CDS             20382..20492
                     /locus_tag="RFE25_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815776.1"
                     /translation="MIEYDLTIILIPILKVAYPFFKKVERKKWYFSGKEV"
     gene            complement(20508..20669)
                     /locus_tag="RFE25_000680"
     CDS             complement(20508..20669)
                     /locus_tag="RFE25_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815777.1"
                     /translation="MAIIEYLYNFSRNKQNFNSAKTAVLSYDLTNLTNFTRTAFKNIY
                     TFLTNIYLL"
     gene            20801..22423
                     /locus_tag="RFE25_000681"
     CDS             20801..22423
                     /locus_tag="RFE25_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501390.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HDU2815778.1"
                     /translation="MKKEKVMDWTTFIGTVAVLLFAVIPMMAFPKASEDIITGINSAI
                     SDSIGSIYLFMGLAIFCFVMYIAFGKYGNVTLGKASDKPEFNTFTWAAMLFCAGIGSD
                     ILYWGVIEWAFYYQVPPNGAKSMSDEALQYATQYGMFHWGPIAWAIYVLPALPIGYLV
                     FVKKQPVYKISQACRPILKGQTDKFVGKVVDILFIFGLLGGAATSLALGVPLISAGIE
                     RLTGLDGKNMILRSAILLTITVIFAISSYTGLKKGIQKLSDINVWLSFVLLAFIFIIG
                     PTVFIMETTVTGFGNMLRDFFHMATWLEPFGGIKGRKETNFPQDWTIFYWSWWLVYAP
                     FIGLFIARISKGRRLKEVVLGTIIYGTLGCVLFFGIFGNYAVYLQISGQFNVTQYLNT
                     HGTEATIIEVVHHLPFPSLMIVLFLVSAFLFLATTFDSGSYILAAASQKKVVGEPLRA
                     NRLFWAFALCLLPFSLMLVGGERALEVLKTASILASVPLIVIFIFMMISFLIILGRDR
                     IKLETRAEKLKEVERRSLRIVQVSEEEQDDNL"
     gene            complement(22594..23157)
                     /locus_tag="RFE25_000682"
     CDS             complement(22594..23157)
                     /locus_tag="RFE25_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="HDU2815779.1"
                     /translation="MTRSQNKQQQLEQAKDIVINSIGQTMDLYGTNRSVGNLYGTMVF
                     EGSMTLDEMRHQLQMSKPSMSAGVKKLQEFDIVKQQFTRGSRKQHFIAEKDFFIFFRN
                     FFTKKFQREIDINVEAVKDAQAIINPLLESSDLTEAETQEAQKIKAQLDHTHVYYEWL
                     EQLTEAIESGEIFKYFPIPEQPSDSEN"
     gene            complement(23246..23341)
                     /locus_tag="RFE25_000683"
     CDS             complement(23246..23341)
                     /locus_tag="RFE25_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815780.1"
                     /translation="MKNVSIYKTTQELSFVSSLDFYLTKHLTLML"
     gene            23410..24900
                     /gene="betB"
                     /locus_tag="RFE25_000684"
     CDS             23410..24900
                     /gene="betB"
                     /locus_tag="RFE25_000684"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HDU2815781.1"
                     /translation="MELLKHLSQRQYIDGEWVESTNKNTRDIINPYNQEVIFTVSEGT
                     KEDAERAILAARRAFESGEWSQETAEKRGKKVRAIADKIKEHREALARLETLDTGKTL
                     EESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPL
                     LQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGD
                     VMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQ
                     ALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVIST
                     EHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVF
                     GPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHPY
                     FAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK"
     gene            25161..26870
                     /gene="betA"
                     /locus_tag="RFE25_000685"
     CDS             25161..26870
                     /gene="betA"
                     /locus_tag="RFE25_000685"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HDU2815782.1"
                     /translation="MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDY
                     FWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQ
                     RGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPAT
                     NPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKN
                     LTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGD
                     SEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIF
                     TRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMY
                     SNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEI
                     SPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVV
                     DASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKP
                     YAK"
     gene            27148..27360
                     /locus_tag="RFE25_000686"
     CDS             27148..27360
                     /locus_tag="RFE25_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterile alpha motif-like domain-containing
                     protein"
                     /protein_id="HDU2815783.1"
                     /translation="MSFYEYIQTFKDDKTPLGELAIWIKEDDSFPKQEKLTENILSYF
                     HQMSNIDHEFLEIVKRSLSLYDQLKS"
     gene            27640..28083
                     /locus_tag="RFE25_000687"
     CDS             27640..28083
                     /locus_tag="RFE25_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDU2815784.1"
                     /translation="MNIYDEYRSYLIEELDDCLTIQKNNDTAYYDVLEAINDLSNDSL
                     CVLNHLYINEGQEETFEQKFLQRNKHLKNVDGFKALRFLRPRTAGRHYIIITLWENRQ
                     AFYHWQNSAEYKHTHKHRGTSKGADVKIINRELSYNIRIELADMV"
     gene            28277..29875
                     /locus_tag="RFE25_000688"
     CDS             28277..29875
                     /locus_tag="RFE25_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDU2815785.1"
                     /translation="MQKSALFAPEKYNIISEIEKYSHIPDKKAILYHNTEGEDISVTY
                     QQLIEQSNKVGNVLASHGLSKGDKVLIMMPRSIATYELYIAALKLGVAIIPCSEMLRT
                     KDLQYRITHGEINAVIALEPFTVEFEKIKEYDALTKFVIAGQKDGWISLEAEKENASN
                     KLEMADTTRDDMAILSYTSGTTGNPKAVTHCHGWGFAHLQMAPKHWLCINEDDLVWAT
                     AAPGWQKWVWSPFLSVLGSGATAFVFNGRFSPETYLELLQKYQINVLCCTPTEYRMMA
                     KLQNLNDYDLTHLHSAVSAGEPLNREVVEQFKKYFNLTVRDGYGQTESTLLIGFLKDT
                     PQRIGSMGKGIPGSSVTVVDDEGNSVPANTKGNIAVPLDLPALFKGYYKEPERTAKAQ
                     TGKYYITGDLAHVDDDGYFWFEGRRDDIIISSGYTIGPFEVEDALTNHPAVKECAVVA
                     KPHDIRGNIVKAFVILQDHTAGDDMLVKELQQFVKNEVAPYKYPREIEFVDDLPKTNS
                     GKIRRVELRDSEIEKWQQQKDSNQ"
     gene            complement(29935..30264)
                     /locus_tag="RFE25_000689"
     CDS             complement(29935..30264)
                     /locus_tag="RFE25_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815786.1"
                     /translation="MAYSILNLYSILIQYKCKINHKKEIQYLHPRKTLQLPLILKIIL
                     NLALIGIVIIVLTHTEFQLNAGDSNVFLLNWDIRGLTSYIFSFLILVALVSKLILIFI
                     TRRQRTS"
     gene            30560..32056
                     /gene="mqo"
                     /locus_tag="RFE25_000690"
     CDS             30560..32056
                     /gene="mqo"
                     /locus_tag="RFE25_000690"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDU2815787.1"
                     /translation="MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPA
                     IESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGS
                     IENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLM
                     MKGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNG
                     QWEVTVKNRLTGEKFKQVTDYVFIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACT
                     NPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNL
                     DLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLY
                     TAGKRVQVIKDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERN
                     FPEYKTEWAPKIKKMIPSYGESLIEDEKLMRKIRKQTSKDLELGYYEN"
     gene            complement(32250..33140)
                     /locus_tag="RFE25_000691"
     CDS             complement(32250..33140)
                     /locus_tag="RFE25_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002478556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose bisphosphate aldolase"
                     /protein_id="HDU2815788.1"
                     /translation="MNKEQLEKMKNGKGFIAALDQSGGSTPKALKEYGVNEDQYSNED
                     EMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVEGKYTADYLADKGVVPFLKV
                     DKGLAEEQNGVQLMKPIDNLDSLLDRANERHIFGTKMRSNILELNEQGIKDVVEQQFE
                     VAKQIIAKGLVPIIEPEVNINAKDKAEIEKVLKAELKKGLDSLNADQLVMLKLTIPTE
                     PNLYKELAEHPNVVRVVVLSGGYSREKANELLKDNDELIASFSRALASDLRADQSKEE
                     FDKALGDAVESIYDASVNKN"
     gene            complement(33263..33679)
                     /locus_tag="RFE25_000692"
     CDS             complement(33263..33679)
                     /locus_tag="RFE25_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815789.1"
                     /translation="MRLKVLFHFIAAIFISFMLLWMTMLFDLISNQSHLKALLLNLDF
                     LIPSDNTPYILEIICHLLIGSVIYFVFVLLFHTSKRLYYLCYIPLFFLFIALYPFLVF
                     IAQRPIFQFSVTELIGWIITHIFFMSLMALVIPRIK"
     gene            33937..35274
                     /locus_tag="RFE25_000693"
     CDS             33937..35274
                     /locus_tag="RFE25_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDU2815790.1"
                     /translation="MSKAHQLIQEDEHYFAKSGRIKYYPLVIDHGYGATLVDIEGKTY
                     IDLLSSASSQNVGHAPREVTEAIKAQVDKFIHYTPAYMYHEPLVRLAKKLCELAPGDF
                     EKRVTFGLTGSDANDGIIKFARAYTGRPYIISFTNAYHGSTFGSLSMSAISLNMRKHY
                     GPLLNGFYHIPFPDKYRGMYEQPQANSVEEYLAPLKEMFAKYVPADEVACIVIETIQG
                     DGGLLEPVPGYFEALEKICREHGILIAVDDIQQGFGRTGTWSSVSHFNFTPDLITFGK
                     SLAGGMPMSAIVGRKEIMNCLEAPAHLFTTGANPVSCEAALATIQMIEDQSLLQASAE
                     KGEYVRKRMDQWVSKYNSVGDVRGKGLSIGIDIVSDKKLKTRDASAALKICNYCFEHG
                     VVIIAVAGNVLRFQPPLVITYEQLDTALNTIEDALTALEAGNLDQYDISGQGW"
     gene            complement(35355..36803)
                     /locus_tag="RFE25_000694"
     CDS             complement(35355..36803)
                     /locus_tag="RFE25_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDU2815791.1"
                     /translation="MGSFFNKIARKEDPAIYQNKDGHLKRTLRVRDFLALGVGTIVST
                     SIFTLPGIVAAEHAGPAVALSFLLAAIVAGLVAFTYAEMAAAMPFAGSAYSWVNVLFG
                     EFFGWVAGWALLAEYFIAVAFVASGFSANLRGLVKPIGIELPAALSNPFGTNGGFIDI
                     IAAIVILLTALLLSRGMSEAARMENILVILKVLAIILFVIVGLTAINVSNYVPFIPEH
                     KVTATGDFGGWQGIYAGVSMIFLAYIGFDSIAANSAEALDPQKTMPRGILGSLSVAIV
                     LFIAVALVLVGMFHYSQYANNAEPVGWALRQSGHGVVAAIVQAISVIGMFTALIGMML
                     AGSRLLYSFGRDGLLPSWLSHLNDKHLPNRALVILTIIGVLIGSMFPFAFLAQLISAG
                     TLVAFMFVSLAMYRLRKREGKDLPIPAFKLPLYPVLPAITFVLVLLVFWGLGFEAKLY
                     TLIWFIVGIILYLSYGLRHSKKNDVAEYHPPK"
     gene            37489..38448
                     /locus_tag="RFE25_000695"
     CDS             37489..38448
                     /locus_tag="RFE25_000695"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDU2815792.1"
                     /translation="MKTFGKKVVLIGDGSVGSSYAFAMVTQGVADEFVIIDIAKDKVK
                     ADVQDLNHGTVHSPSPVDVKAGEYEDCKDADLVVITAGAPQKPGETRLQLVEKNTKIM
                     KSIVKSVMDSGFDGYFLIAANPVDILTRFVKEYTGLPAERVIGSGTVLDSARLQYLIS
                     QELGVAPSSVDASIIGEHGDTELAVWSQANVAGISVYDTLKEQTGSEAKAEEIYVNTR
                     DAAYEIIQAKGSTYYGIALALMRISKAILNNENNVLNVSIQLDGQYGGHKGVYLGVPT
                     LVNQHGAVKIYEMPLSAEEQALFDKSVKILEDTFDSIKYLLED"
     gene            38726..39430
                     /gene="budA"
                     /locus_tag="RFE25_000696"
     CDS             38726..39430
                     /gene="budA"
                     /locus_tag="RFE25_000696"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDU2815793.1"
                     /translation="MTNVLYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDG
                     EVIFLDGKAYHANEHKEFIELKGDEKVPYASITNFKASKTFPLQQLSQDDVFAQIKNE
                     MLSENLFSAVKIYGTFKHMHVRMMPAQQPPYTRLIDSARRQPEEKRQDIRGAIVGFFT
                     PELFHGVGSAGFHIHFADDERAYGGHVLEFEVDDVVVEIQNFETFQQHFPVNNETFVK
                     AKIDYKDVAEEIREAE"
     gene            complement(39516..40376)
                     /locus_tag="RFE25_000697"
     CDS             complement(39516..40376)
                     /locus_tag="RFE25_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDU2815794.1"
                     /translation="MLSVAIIGPGAVGTTIAYELQQSLPHTTLIGRHAKTITYYTVPH
                     APAQDIVVKGYEDVTNTFDVIIIAVKTHQLDAVIPHLTYLAHEDTLIILAQNGYGQLE
                     HIPFKNVCQAVVYISGQKKGDVVTHFRDYQLRIQDNALTRQFRDLVQDSQIDIVLEAN
                     IQQAIWYKLLVNLGINSITALGRQTVAIMHNPEIRILCRQLLLDGCRVAQAEGLNFSE
                     QTVDTIMTIYQGYPDEMGTSMYYDIVHQQPLEVEAIQGFIYRRAREHNLDTPYLDTIY
                     SFLRAYQQNM"
     gene            40449..41267
                     /gene="panB"
                     /locus_tag="RFE25_000698"
     CDS             40449..41267
                     /gene="panB"
                     /locus_tag="RFE25_000698"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDU2815795.1"
                     /translation="MKTVSQLIDMKQKQTKISMVTAYDFPSAKQVEAAGIDMILVGDS
                     LGMTVLGYESTVQVTLADMIHHGRAVRRGAPNTFVVVDMPIGAVGISMTQDLNHALKL
                     YQETNANAIKAEGAHITPFIEKATAIGIPVVAHLGLTPQSVGVMGYKLQGATKEAAEQ
                     LILDAKNVEQAGAVALVLEAIPNDLAEEISKHLTIPVIGIGAGKGTDGQVLVYHDMLN
                     YGVEHKAKFVKQFADFSVGVDGLKQYDQEVKSGAFPSEEYTYKKKIMNEVNNND"
     gene            41260..42111
                     /locus_tag="RFE25_000699"
     CDS             41260..42111
                     /locus_tag="RFE25_000699"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDU2815796.1"
                     /translation="MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRE
                     SVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDIYPG
                     ELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQ
                     MVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGE
                     RQSKVIIDRVTEYLESHISGRIEEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLID
                     NIIIGAE"
     gene            42113..42496
                     /locus_tag="RFE25_000700"
     CDS             42113..42496
                     /locus_tag="RFE25_000700"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015901315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HDU2815797.1"
                     /translation="MIRTMMNAKIHRARVTESNLNYVGSITIDSDILEAVDILPNEKV
                     AIVNNNNGARFETYVIAGERGSGKICLNGAASRLVEVGDVVIIMTYAQLNEEEIKNHA
                     PKVAVMNEDNVIIEMIHEKENTIVL"
     gene            42839..43915
                     /locus_tag="RFE25_000701"
     CDS             42839..43915
                     /locus_tag="RFE25_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like serine protease"
                     /protein_id="HDU2815798.1"
                     /translation="MTKIFKISFLILLVVIVSSYYGESFVLADNNPIVNSENGSDNNF
                     ESGTIERNQNELYEVGDYSTPLTERVFGKDQRTVVNNILQRPYKQTVLLNMTFSNNRV
                     YKGTGTMIGKDIVLTAAHNVYSKDDKGWAKKIDVYAGVNGQTYTIGKAFSHKFFVSKT
                     WINNAPTKEDIAIIKLNSNLGNKTGYLTLNTHISKGENIEISGFPGDKSDNRQYKGKG
                     KLESFDENEMYYTVDTFSGQSGSAIRDSKNNIIGVHAYGRYNHNSGVRINDLKLDYIN
                     YWIGKYRSHPYNKKVKVIKSKYIYWKNIEITKKGDNKLIKKDKAYTAKLYYNIPNGYK
                     YYSLYDEKNRWMGYFNSNDIKVVK"
     gene            43931..44566
                     /locus_tag="RFE25_000702"
     CDS             43931..44566
                     /locus_tag="RFE25_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002955208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDU2815799.1"
                     /translation="MKKVISLFVAILSVLIFTDNANAENNKPEGVNENSNLIPVRQPD
                     ANYPGPVSDIARVKKLDNLIDGTKDPDVIKQLKDDNEVPNNAVKAKDSKIVSDCRHLL
                     KHPDNLIDGTKDPNVINQLKNANGTSNNSAVNPSIKANDIHTKSNKQMAKQQSIHLDS
                     KSKSVHKQQLKELPKTGVNNESNTAIMALFIGLILLVVSLVTRFIKLNSHQ"
     gene            complement(44664..46346)
                     /locus_tag="RFE25_000703"
     CDS             complement(44664..46346)
                     /locus_tag="RFE25_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDU2815800.1"
                     /translation="MNQHLLGNPKLTVTHVNEVKTGINHIVVDSVQYGNQEMIMEKDV
                     TVEMRDGEKLYINIFRPNKDGKFPVVMSADTYGKDNKPKITNMGALWPTLGAIPTSSF
                     TPEESPDPGFWVPNDYVVVKVALRGSDKSKGVLSPWSKREAEDYYEVIEWAAKQPWSN
                     GNIGTNGVSYLAVTQWWVASLNPPHLKAMIPWEGLNDMYREVAFHGGIPDTGFYRFWI
                     QGIFARWTDNPNIEDMIQAQQEHPLFDDFWKQRQVPLSQIKTPLLTCASWSTQGLHNR
                     GSFEGFKQAASEEKWLYVHGRKEWESYYARENLERQKSFFDFYLKEENNDWKDTPHVI
                     YEVRDQFYKGEFKSASAFPLPNTEYTPLYLNAENHTLNHAKISSAYVAQYDSEDKRQD
                     VSFKYTFDKDTELVGNMNLKLWVSTTDSDDMDLFAGIKKLDRRGNEVNFPDFNHIENG
                     QVATGWLRVSHRELDQEKSTIAQPWHKHETELKLSQDEIVPVEIELLPSGTLFKQGET
                     LEVVVKGSEIVIGNSTPGMKTRYEHEETINNGMHMIYTGGKYDSQLIIPIVN"
     gene            46403..46511
                     /locus_tag="RFE25_000704"
                     /pseudo
     CDS             46403..46511
                     /locus_tag="RFE25_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501367.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            46489..47076
                     /locus_tag="RFE25_000705"
     CDS             46489..47076
                     /locus_tag="RFE25_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDU2815801.1"
                     /translation="MTIDRRIRKSQVAMRNAFIELLHQHQLEEITVQQIADLADVNRS
                     TFYTHYYDKYDLLEKLEDQQLEEIRDFIHDEKLNGAVKLSTDNIHQIMTVLIDMIEKD
                     IAFYQLMFRMGKDSNIHEKLYDLIMCHLQRYKNENDQINGIPFSYFMSYVSGAGLSLI
                     RHWVEDPNRIDKVDLIMHFNTIVNQGPATIIKNIQ"
     gene            complement(47157..47606)
                     /locus_tag="RFE25_000706"
     CDS             complement(47157..47606)
                     /locus_tag="RFE25_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/extradiol
                     dioxygenase family protein"
                     /protein_id="HDU2815802.1"
                     /translation="MTALFPYIAFENSKEALAYYEEVFGATDVKRLEVGEEQASHFGM
                     TKEEAQEATMHAEFEVLGVKVLCSDSFGRADKINNGISLLIDYDVNNKEDADKVEAFY
                     EKIKDHSSIEIELPFADQFWGGKMGVFTDKYGVRWMLHGQDYTAIQQ"
     gene            47960..48682
                     /locus_tag="RFE25_000707"
     CDS             47960..48682
                     /locus_tag="RFE25_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDU2815803.1"
                     /translation="MINAEPIISKMKNQKINYDKVLKKLIGQWEREAIRPKILLHSCC
                     APCSTYTLEFLTQYADIAIYFANSNIHPKNEYLRRAKVQEQFVEDFNRKTGANVKYIE
                     APYEPHKFVKMVKDKELADEKEGGLRCTACFEMRLDIVAKAAVEHGYDYFGSAITLSP
                     KKNAQLINELGMDVQKIYDVNYLPSDFKKSKGYERSIEMCNDYNIFRQCYCGCVFAAM
                     QQGIDFKTVNKEAKAFLEQYPD"
     gene            complement(48868..49143)
                     /locus_tag="RFE25_000708"
     CDS             complement(48868..49143)
                     /locus_tag="RFE25_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815804.1"
                     /translation="MTKETDNKKTVATSDNKDTQQQNQTEEDERQGLNGYRKTDLDLE
                     IEQELREMMKTGENETKNDYKKFKVFSLISTLVIVILAIIRFVHKMI"
     gene            complement(49298..50362)
                     /locus_tag="RFE25_000709"
     CDS             complement(49298..50362)
                     /locus_tag="RFE25_000709"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HDU2815805.1"
                     /translation="MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTY
                     KNPTLSQTIQGNTYDNPIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQP
                     RMFRLLEDDALINRMGFNNIGMNKALSHLRKNAYQVPVGINVGVNKMTPYEARYQDYI
                     KVIDTFKHDVSFFTVNISSPNTENLQNFHDKDEFSMLCQALTTFKKQHDVTVPIYLKL
                     TSDMDFDGLKALLPAITETFDGIILANTTRQRDGLTSANKVEEGGLSGRPLFERNLKL
                     IKYAYQQTNGEFLIIGTGGVFSTEDAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGI
                     ARYLKDHHFDNVSDIIGLDA"
     gene            50580..51446
                     /locus_tag="RFE25_000710"
     CDS             50580..51446
                     /locus_tag="RFE25_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDU2815806.1"
                     /translation="MNEQWLEHLPLKDIKEISPVSGGDVNEAYRVETDTDTFFLLVQR
                     GRKESFYAAEIAGLNEFERAGITAPRVIASGEVNGDVYLVMTYLEEGASGSQRQLGQL
                     VAQLHSQQQEEGKFGFSLPYEGGDISFDNHWQDDWRTIFVDKRLDHLKEELLNRGLWD
                     ANDIKVYDKVRSQIVEELEKHQSKPSLLHGDLWGGNYMFLKDGRPALFDPAPLYGDRE
                     FDIGITTVFGGFTSEFYDAYNKHYPLAKGASYRLEFYRLYLLMVHLLKFGEMYRDSVA
                     HSMDRILQGTTS"
     gene            complement(51820..51903)
                     /locus_tag="RFE25_000711"
                     /pseudo
     CDS             complement(51820..51903)
                     /locus_tag="RFE25_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(51904..>52335)
                     /locus_tag="RFE25_000712"
     CDS             complement(51904..>52335)
                     /locus_tag="RFE25_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815807.1"
                     /translation="LFFLALTPIIDLILLITTVVDLMNGATAEMPHAIAAVYISISLV
                     FGKSMINWADDRFRYYVMKQGSKPYKLDGLAYSKNYAKSWLKHLLSYIIGTGILHLIV
                     YLINDKSRTEAMDGVIHIWTIVIIIDLIICISYFVWPPKRN"
BASE COUNT        18346 a         7858 c         9669 g        16462 t
ORIGIN      
        1 ggtgatgaaa aatttagaac ttctaagttt ttgaaaagta aaaaatttgt aatagtgtaa
       61 aaatagtata ttgatttttg ctagttaaca gaaaatttta agttatataa ataggaagaa
      121 aacaaatttt acgtaatttt tttcgaaaag caattgatat aattcttatt tcattataca
      181 atttagacta atctagaaat tgaaatggag taatattttt gaaaaaaaga attgattatt
      241 tgtcgaataa gcagaataag tattcgatta gacgttttac agtaggtacc acatcagtaa
      301 tagtaggggc aactatacta tttgggatag gcaatcatca agcacaagct tcagaacaat
      361 cgaacgatac aacgcaatct tcgaaaaata atgcaagtgc agattccgaa aaaaacaata
      421 tgatagaaac acctcaatta aatacaacgg ctaatgatac atctgatatt agtgcaaaca
      481 caaacagtgc gaatgtagat agcacaacaa aaccaatgtc tacacaaacg agcaatacca
      541 ctacaacaga gccagcttca acaaatgaaa cacctcaacc gacggcaatt aaaaatcaag
      601 caactgctgc aaaaatgcaa gatcaaactg ttcctcaaga agcaaattct caagtagata
      661 ataaaacaac gaatgatgct aatagcatag caacaaacag tgagcttaaa aattctcaaa
      721 cattagattt accacaatca tcaccacaaa cgatttccaa tgcgcaagga actagtaaac
      781 caagtgttag aacgagagct gtacgtagtt tagctgttgc tgaaccggta gtaaatgctg
      841 ctgatgctaa aggtacaaat gtaaatgata aagttacggc aagtaatttc aagttagaaa
      901 agactacatt tgaccctaat caaagtggta acacatttat ggcggcaaat tttacagtga
      961 cagataaagt gaaatcaggg gattatttta cagcgaagtt accagatagt ttaactggta
     1021 atggagacgt ggattattct aattcaaata atacgatgcc aattgcagac attaaaagta
     1081 cgaatggcga tgttgtagct aaagcaacat atgatatctt gactaagacg tatacatttg
     1141 tctttacaga ttatgtaaat aataaagaaa atattaacgg acaattttca ttacctttat
     1201 ttacagaccg agcaaaggca cctaaatcag gaacatatga tgcgaatatt aatattgcgg
     1261 atgaaatgtt taataataaa attacttata actatagttc gccaattgca ggaattgata
     1321 aaccaaatgg cgcgaacatt tcttctcaaa ttattggtgt agatacagct tcaggtcaaa
     1381 acacatacaa gcaaacagta tttgttaacc ctaagcaacg agttttaggt aatacgtggg
     1441 tgtatattaa aggctaccaa gataaaatcg aagaaagtag cggtaaagta agtgctacag
     1501 atacaaaact gagaattttt gaagtgaatg atacatctaa attatcagat agctactatg
     1561 cagatccaaa tgactctaac cttaaagaag taacagacca atttaaaaat agaatctatt
     1621 atgagcatcc aaatgtagct agtattaaat ttggtgatat tactaaaaca tatgtagtat
     1681 tagtagaagg gcattacgac aatacaggta agaacttaaa aactcaggtt attcaagaaa
     1741 atgttgatcc tgtaacaaat agagactaca gtattttcgg ttggaataat gagaatgttg
     1801 tacgttatgg tggtggaagt gctgatggtg attcagcagt aaatccgaaa gacccaactc
     1861 cagggccgcc ggttgaccca gaaccaagtc cagacccaga accagaacca acgccagatc
     1921 cagaaccaag tccagaccca gaaccggaac caagcccaga cccggatccg gattcggatt
     1981 cagacagtga ctcaggctca gacagcgact caggttcaga tagcgactca gaatcagata
     2041 gcgattcgga ttcagacagt gattcagatt cagacagcga ctcagaatca gatagcgatt
     2101 cagaatcaga tagcgactca gattcagata gcgattcaga ttcagatagc gattcagaat
     2161 cagatagcga ttcggattca gacagtgatt cagattcaga cagcgactca gaatcagata
     2221 gcgactcaga atcagatagt gagtcagatt cagacagtga ctcggactca gacagtgatt
     2281 cagactcaga tagcgattca gactcagata gcgattcaga ctcagacagc gattcagatt
     2341 cagacagcga ctcagactca gacagcgact cagactcaga tagcgactca gactcagaca
     2401 gcgactcaga ttcagatagc gattcagact cagacagcga ctcagactca gacagcgact
     2461 cagactcaga tagcgattca gactcagaca gcgactcaga ttcagatagc gattcggact
     2521 cagacagcga ttcagattca gacagcgact cagactcgga tagcgattca gattcagaca
     2581 gcgactcaga ctcggatagc gactcggatt cagatagtga ctccgattca agagttacac
     2641 caccaaataa tgaacagaaa gcaccatcaa atcctaaagg tgaagtaaac cattctaata
     2701 aggtatcaaa acaacacaaa actgatgctt taccagaaac aggagataag agcgaaaaca
     2761 caaatgcaac tttatttggt gcaatgatgg cattattagg atcattacta ttgtttagaa
     2821 aacgcaagca agatcataaa gaaaaagcgt aaatactttt ttaggccgaa tacatttgta
     2881 ttcggttttt ttgttgaaaa tgattttaaa gtgaattgat taagcgtaaa atgttgataa
     2941 agtagaatta gaaaggggtc atgacgtatg gcttatattt cattaaacta tcattcacca
     3001 acaattggta tgcatcaaaa tttgacagtc attttaccgg aagatcaaag cttctttaat
     3061 aacgatataa ctgctaaacc attaaaaact ttaatgttgt tacatggatt atcaagtgat
     3121 gaaacgacat atatgagata tacaagcata gaaaggtatg cgaatgaaca caaattaggt
     3181 gtgattatgc ccaatgtgga tcatagcgca tatgctaaca tggcatatgg tcatagctat
     3241 tatgattata ttttggaagt atatgattat gttcatcaaa tatttccact ttccaaaaag
     3301 cgtgatgaca attttatagc aggtcactct atgggaggat atggcacaat taaatttgca
     3361 ttaacacaag gggataaatt tgccaaagct gtaccattat ctgctgtgtt tgaagcgcaa
     3421 aatttaatgg atctagagtg gaatgatttt tcaaaagagg ccataattgg caatctttca
     3481 agtgttaaag gaactgaaca tgatccgtat tatttgctag acaaagctgt agctgaagat
     3541 aaacaaattc caaaattgct cattatgtgt ggtaaacaag actttttata tcaagacaac
     3601 ttagatttta tcgattattt atcacgtaaa aatgttcctt atcaatttga agatggacca
     3661 ggagatcatg attatgcata ttgggaccaa gcgattaagc gtgctataac atggatggtg
     3721 aatgattaat tatttcctgg aaaatatgtg gttgcattaa atacacagag tgagagatac
     3781 aaactattta cgcacgacta acatttctga gtgtttaaat taaatttgta ttaatatgat
     3841 tggcgcaatt tgctgatacg caaaaatgtt tctcgtgaaa cttagattta gcttatagtt
     3901 ttatcatcat ttgtatgact tacattataa attttattat aatgaggtta acgctttgaa
     3961 aggagtcatc atcatgtcga ccaataaaaa cgattatgag catatgttgt tttattttgc
     4021 atataaaacg tttattacta ccgctgatga aattatagag aagtatggta tgagccgtca
     4081 gcatcatcgt tttttgtttt ttatcaataa attacctggt attactatta aatcattact
     4141 agaaatatta gaaatttcta aacaaggatc acatgcaaca cttcaaaaat taaaagagca
     4201 aggtctcatt attgaaaaag ttttagagac tgatcgacgt gtcaaaaaat tatattcgac
     4261 ggataaaggc gatcaactca ttgctgaatt gaacaaggcg caagatgaat tattgcaaaa
     4321 tatatatcaa caagtcggtt cggattggta tgatgtgatg gaagcattgg ctaaagggcg
     4381 acctggcttt gattttatta agcatttgaa agatgaaaaa gaaagctagc atcagaaatg
     4441 ttaaaaatct tcgcattctt aaatttaaaa aatatgtcaa aaagtgtata ataaaaacat
     4501 ataatttaat tgaactcagt ttcaacacat cttagaaagg agtttgaatg atgaaaaaat
     4561 tagcagttat tttaacatta gttggcggtt tatactacgc atttaaaaaa taccaagaac
     4621 gtgttaacca agcacctaac attgagtact aaattaaacc ataaaaaatt cccgaacacc
     4681 ttgttatagt gctcgggaat ttttttatgc tttacttgaa tatatcaaat attatttttg
     4741 cgctttctgt attttcgata ttaccactaa atgattctga tctaggtccg taagcgtagg
     4801 tattaacatc ctcgcctgta tgtccatcgg aagtccaccc tgtataagat ttatcattta
     4861 ctggcttctg aattgcgtgt tgtaaggctt ttgtttgttt ttctacatct gcagattttt
     4921 cgtctttttc ttttttaagt aatttttgca actttttatt ctctttttta acctttttca
     4981 tatcatcttg tgaaaattca aagccataac cttcattaat aactttttca gggtcttcac
     5041 ctttagccat tttttctgtc atatatgatc cagagtgttt catcgattta atcggttgag
     5101 gattccattc gtatccttta tctttaccaa ttgttagacc accagtagag tgatctgctg
     5161 ttgcaacgac aagtgtatct ttatgtttct tagcatattg aatggcgtca tcgaatgctt
     5221 tttcaaaacc ttccatttca gacataacgc ctgtaatatc gttggaatgc gctgatttat
     5281 ctatagaagc accttcgacc attaaaaaga aacctttttt attacgctca agcttactaa
     5341 gtgcactttg ttgcatatca gctaatgatg gttcgtcttt agaagcatct attgcaagtg
     5401 gcatattttt atctgcaaac aaaccaagaa ctttatcttt atcagatttt gataaatcct
     5461 tactgttcgt ggcaaggtcg taaccatctt ttttgaattt tttatctaaa ttgccattac
     5521 ttttaccgaa atatttagcg ccgccgccta ataaaacatc aactttatgc tttccgttga
     5581 ttttatcttt ataaaattgt ttagcgattt cgtttttatc atctctagaa gtcacgtgtg
     5641 cagcatatgc tgctggtgtt gcatctgtta attcagctgt tgaaacaaga ccagtcgact
     5701 tacctttttc ttttgcacgt tcaagcactg tctttacttt ctgcttgtta ctgtcaacac
     5761 cgacggcacc attatatgtc ttatggccag aactaaaggc tgttccgcca gctgcagaat
     5821 cagtaatatt ctgttttggg tcatttgaat atgtacgatt tgtgcctttt aaatatgaat
     5881 caaaagcagt aggggtcatt tctttggcat gcgaatcatt tttataataa cgataagctg
     5941 tgttaaatga tggacccatg ccatcgccaa ctaaaaagat aacatttttt ggatttttag
     6001 tattaccaac cgcgaaactt tcatctttag aacttttatc ggattgcgca attgcaggtg
     6061 tgacagaact gaaaactgtt gacacgataa taaggttagc aactgcaaat tttgtggctt
     6121 ttttaactga taacataata catcctcctg agtatatgac tatgtcttca gtgtaaaaga
     6181 ggaattttga gcaattatgt agttttagtt aaaaatatgt aaacagagtg atttagaata
     6241 acaaaaaatg aatatatatg acaatttgtt atagaaagcg ttagaataga agcgtgtgaa
     6301 aatatagaat taaatataat ttgaggtgga aaaatgatac tagtaatgtt atctccatta
     6361 ttaatcatat tctttatagt gttgtctatt ttagaggagc gtaaacgtac gaagaaaaag
     6421 caactcgaga aagaaaaagc aaatacacta aatcaaaata caaatgacac ggaaagttca
     6481 aatcaagagc cgtcattgca gcagactaaa gaacaaaaag ataacaaagg ataattcaat
     6541 tgaaggaaga agattataga tgaaaatatt aattgttgaa gatgattttg ttatagcaga
     6601 aagtttagca tctgaactta aaaaatggaa ttacggtgtt attgtcgttg aacaatttga
     6661 tgatatactg tctatcttta accaacatca acctcagctt gtattgctag atattaattt
     6721 gccaacgtta aatggttttc attggtgtca agaaatccga aaaacatcta atgtgccaat
     6781 tatatttatt agttcccgta ttgataatat ggaccaaatt atggcaatac aaatgggggg
     6841 agatgatttt atcgaaaagc catttaactt gtcattaacg attgccaaaa ttcaagcatt
     6901 attgagacga acttatgact tgtcagtagc taatgattca ttgacggtta aaggttgtac
     6961 attaatatta gatgaagcaa aagtcgtgta tcaagaacaa aacatacagc tatctttgac
     7021 tgaattacaa atattaaagt tattatttca aaatgaagat aaatatgtaa gtagaactgc
     7081 tttaattgaa aaatgttggg aatcagaaaa cttcatagat gataacacat tagctgttaa
     7141 catgacgcgc ctgcgtaaaa aattaaatac tattggcgtt aatgatttta tcattacaaa
     7201 gaaaaatgtc ggatataaag tatagggtga atgcaatgac ctttcttaaa agtattactc
     7261 aggaaatagc aatagtcata gttatttttg ctttatttgg cttaatgttt tacctgtatc
     7321 atttgccatt agaagcatat ttactagcac ttggcgttat tttattatta ttactcatat
     7381 tcataggtat taaatattta agttttgtaa aaactataag ccaacaacaa caaattgaaa
     7441 acttagaaac tgcgttgtat cagcttaaaa atgaacaaat tgaatataaa aatgatgtag
     7501 agagctactt tttaacatgg gtacatcaaa tgaaaacacc cattactgca gcacaactgt
     7561 tacttgaaag agatgagcct aatgttgtta atcgtgttcg tcaagaggtt attcaaattg
     7621 ataactatac aagtttagca cttagttatt taaagttatt aaatgaaact tctgatattt
     7681 ctgtcactaa aatttcgatt aataatatca ttcgcccaat tattatgaaa tattcaatac
     7741 agtttattga tcaaaaaaca aaaatccatt atgaaccttg tcatcacgaa gtattaactg
     7801 acgttagatg gacctcttta atgatagaac aattaataaa taatgcactt aagtatgcga
     7861 gaggtaaaga tatatggatt gaatttgatg agcaatccaa tcaattacac gtaaaagata
     7921 atggtatcgg tattagtgaa gcggacttgc ctaaaatatt tgataagggc tattcaggtt
     7981 ataatggcca gcgccaaagt aactcaagtg ggattggttt atttatcgta aaacaaattt
     8041 caacacacac aaaccatcct gtttcagtcg tatctaaaca aaatgagggt acaacattta
     8101 cgattcaatt tccagatgaa taaaaacttt caatattgta agtatactag taacattttt
     8161 ttactaattt aaatgttatt agtatttttt tgttttaata tagaactaac aaagaaatga
     8221 ggtgcatgcc atgttgctag aagtgaaaca tgtaaaaaag gtttatggta aaggtttgaa
     8281 tgctacgaca gcacttaatc aaatgaattt atcagttgga gctggtgaat ttgttgcaat
     8341 tatgggtgag tctgggtcag ggaagtctac actactaaat ttaattgctt cttttgatgg
     8401 actaactgaa ggtgacatta ttgtggatgg cgcacattta aataatatga aaaataaaag
     8461 taaagcattg tatcgtcaac aaatggtagg ttttgttttt caagatttta atcttttacc
     8521 aacaatgacg aataaagaaa atataatgat gccattaatt ttagctggtg ctaaacgaaa
     8581 agatatagaa caaagggtac atcagttggc agtacaatta catttagagg gattcttaaa
     8641 caagtatcct tctgaaatct ctgggggtca gaagcaacgc attgccattg cacgtgcatt
     8701 agttactaag ccgacgattt tactagccga tgaacctaca ggtgcacttg attcaaaaac
     8761 gtcaaaggca ttgatgatgt tatttcaaga gattcatcaa ttggaacaga caattttaat
     8821 ggtaactcat tcaaatatcg atgcgtctta tgcagagcga gtcattttta ttaaagatgg
     8881 gcgtctatat catgaaatat atcgtggtga agaaagtcaa ttagcttttc aacaacgaat
     8941 aacagatagc ttagcacttg tgaatggagg aagtgtcaat atatgaagtt aagattgtta
     9001 tggcacatag tgcgacgtca atttattacg cagcgacttg taatcattcc attcatttta
     9061 gcggtaagtg tactattcat gattgaatat acgcttgtgt caattgggtt aaatagctac
     9121 ataaaacaga agaatgactt cctagtacca tttattatca tagctaattt ttttatggcg
     9181 cttttaactt ttatttttat tttctatgca aatcacttta tgatgtcaca aagacgaaaa
     9241 gagtttagca tttttatgac attgggcatg accaagaaaa gtatgcgttt aattgtagtg
     9301 atggaaacta tcttacaatt tgtgataatt tcagtcgtta gtattgccgg cggatactta
     9361 cttggtgcga tatttttctt gtttatacag aaaataatgg gcagtgaagt tgcgacgtta
     9421 aggtattatc catttgactc tgtagcgatg tttattactt tgattatcat tgctgtatta
     9481 atgggcatgc tacttatatt caacttgttc agtattaatt ttcaacggcc gataacttat
     9541 caacatcgtt ccgattctag tgtcatatca cgatggttgc gttacgtttt aattgttata
     9601 ggaagcgcag cactatattt aggttacttt attgcattac aacaagatac gacgtttggt
     9661 gcctttttta aaatatggat tgtcatagga ttagttatta tcggtactta tgcatttttt
     9721 gtaggtataa gtgaaataat tattagtata ttgcagcagg tatcaaaagt ttactatcat
     9781 ccacggtatt tttttgtggt agttgggatg cgtgtacgtc ttaaaatgaa tgcagtcagt
     9841 cttgcaacaa tcactttgct gtgtacattt ttgattgtaa cgctcacaat gacattaaca
     9901 acctatcgtg atatgaatca taccattacg aaattgatta cgaatgatta tgatttgtca
     9961 tttagcgaca attctaagtc acaaatagaa cgtcaacaaa caattgagaa tattaaacgt
    10021 gatatacagg gttcggttaa tgcaaaagac ttcaaagtat atgaaacgac attatttaga
    10081 gcttctttag aaaagaatcg tgcttattac aagttaaaac aggctagtga tgatattcca
    10141 atagacttca ttggtaatga aggcgcgata ttttcaagac aatcagtaat gattacagct
    10201 tttactgcac aagattataa tcgatatcac caaaacaaat tacacttaga caatcaaagt
    10261 ataggtatga ttacgaatgt acctattttt aaaaagcagt ctaaggtcgg tcttaataat
    10321 gaagtcttta aagtgaaaca acttgacgca catgcgttaa atttgatgat gattcaagat
    10381 agtatggttt taattgttaa agataacaat caattacaaa aagtaaaagg attttatgca
    10441 catgaacaaa agaattcgac aatatcgata aactttaatg tatttggaaa gacgaaatta
    10501 acaacatcac aaatacaaaa gctatcgaaa aaatacgatg cgtcaataaa ttctaaatca
    10561 gaaatgctaa tggtttggga tcgtttgaca ggtggactaa tatttgtagg tggcgtagta
    10621 tcaattgtac ttgtcattgg aatatttcta atgatgtact ataaacaagt ctcagaagcc
    10681 tatgcaaatc agcacaatta tgacattatg aaaaaacttg gtttagataa tggaagaata
    10741 gcaaagataa cacgaaatca aatgactttc ttgttcgcaa taccaataac agtagcactg
    10801 attcacacat taatttctag taacattgta tatacgttac taaatatgat aggtattaat
    10861 aaccatcata tatttttaac aagttacgta ctagctgtca ttataatttc gtttctatat
    10921 atggcgatgt acaaaataac ttcctatatt tatgctaaag ttattcatca acaacgtaat
    10981 taaccatgtt tcagtgaaat cacaatcaat catgtatttt cactgaaata tattatatta
    11041 aaaagaaacc taaaaacatt acaaataaca ataccaaatt tgaaccgata agataaaatg
    11101 tcttgtcggt ttttaatata acaagtgata ttttggaaat accaaaaata tatagattgt
    11161 ttatataaaa tgatttaaaa tgttttataa caacatattt tatgcaacac ataaaatggg
    11221 taactaacat cacgaaatca ttgtatttgt tgttacactg atgaagcgat gtcacaaaga
    11281 aatgtcgtta tcaaacgaag cccgaaatac atactgatac tcgaaataat gtaacgataa
    11341 ataacaatga taacgattga ttactacgca aaaatatatg taaattgacg atttaaatgc
    11401 aattcgtata ttttgccaat gatttacaca ttaaaatgtt tgaaaattgt cacaattcag
    11461 tctaatttaa aaggaagtta attacaaaat tcaaaaatca tgcatcgtgt catttagata
    11521 ttgaaaaaga tgagtcaaat ttgtttcata tattttccaa taacaaatta ttatatctaa
    11581 atatacaatc agaaatatat gaatagaaat atcaataaga aaaataatat gattaaaaat
    11641 gatgaatggc atacttataa attgtctaaa tattggcggt caatattact tataaacacg
    11701 aatgttaagt aatgtagaca atgctgaaaa aacaataagt agaaactcta tatagaatgt
    11761 tcgtttttat ttttaataat tgaataatca ttattgatga tttaatatgt attcggtcgc
    11821 acacgataca aagtgacttg ttttaatgat atgcaataat atgacgttta tcgtcgcgtg
    11881 taacaatgta tgagtgtgtc agtttaattt taaaagggtt ataaggatat ttaataagat
    11941 aaaggagggc ttaataaaca atcacatgtg aagtttttaa ggattatatg agttgggcag
    12001 ctctttaatc catagttata acgaatttta aattgttaga tctaacgtat ggtatcagta
    12061 tgtatgagtt taacttaagt attaatctat agtttaaaga gcggtctaat tgtcttttta
    12121 aaaatagaaa ataaggatga ttataatgag gggttataac gaaagatatt gtagctggac
    12181 taatacagct atacaatgtg attattttaa taaagtaaga caggtgaaaa aagacggtaa
    12241 atcggatagg ttgagcaaca acataaactc gaacattatt tatcgtgtgc tcgaaaaatg
    12301 tatcacgcta tataatgtat gttcgcggtg taaacgcgca cttattttat cagaacattc
    12361 taaaaagaat atattcaata taaaaaaggc tgtgtagggg tgtcttatga ataatagaaa
    12421 tgtgtatgat atcgaagtaa gtgattataa aggcttaact tataaattag aagcatttag
    12481 aggtaaagtg attttagttg ttaatactgc aacagaatgt atatatagcg aacaattgaa
    12541 aaaactagag actttgtttc aaaaatataa ggatcgtggg tttgtagtgt tgagttttcc
    12601 gaataataat tttgacaatc gacaaccagg ttctaatgaa gaaatcttga aaattagtcg
    12661 tgagaaattt ggtgttacat ttccagtgct agctaaaata tctgtgaacg ggaacgatga
    12721 acatccgtta tttacgcatt taaagaatga acaaccagga atctttgggt ccccaataaa
    12781 atggaatttc acaaaattta taatcgatcg acaaggcaat gttgtaaatc gattcttgcc
    12841 aatggaagat ccattggata tatcgacaaa tatagaaata ttattgcaag aatcttcatc
    12901 ttaaatttaa aattgagcgc ttagtatgca aataacacaa gagcctctta atgatgtact
    12961 aatagtatgt cattaggagg cattttatat ttagaaaatc agtaatttga cctattttac
    13021 tgaaaggctg atttggtaca taataaatag taaataaata aaaaataaca acgatgcatt
    13081 actgtatgca ttaataactg acacgacata atcaaagttt tgtctgaatt actgataatg
    13141 tcattcaagc aacatgaaag ttgtaaatat ttgcaagtat aactatcaga cacaactcaa
    13201 gtttgtttta atttatacca tacatattaa aaaattgact aaactatcga taaaaaaaga
    13261 gtcaatcatc tatttcaagt ttattgaggt gaaacatttg aaattaaata catctaatag
    13321 tccatttaca gaaaaacaag tcacagagat taacaatctg ctgcaaacat taacagagag
    13381 ccaacaacag tggcttagtg gttttttact agctaatagt aacgatacga caagtgatag
    13441 taatcaacaa caattagaga cagaagtgtg gcaacaatca caaatatcag aagaacaagc
    13501 aacttcaaca acgtatatgt tacaaaataa agagccacat atcgaagcta atcagcggca
    13561 tgttacagtg ctatatggtt ctgaatcagg taatgccatg cgtttagctg aaattttttc
    13621 agaacgttta agtgatatcg gacatcaagt tgttttgatg tcaatggatg aatatgatac
    13681 gacaaacatc gcacagttag aagatttatt tattattacg tctactcatg gtgaaggaga
    13741 accgcctgat aatgcatggg atttctttga atttttagaa gacgataacg cacctaattt
    13801 aaatcatgtg agatattcag tactagcttt aggtgatcaa acatatgaat ttttctgtca
    13861 agctggtaaa gatgtagatg ctttactaga aaatctaggc gctgagcgta tatgtaagcg
    13921 tgtagattgt gatattgatt atgaagaaga cgcagaaaag tggatggcag acatcattaa
    13981 tatgattgat actacatcag aaggtattca aagtgaatcg gtgataagtg aatcaattaa
    14041 gtctgccaaa gaaaagaaat attctaaatt aaatccatac caagcagaag ttttagcgaa
    14101 tatcaattta aatggtaccg attcaaataa agaaacacga catatagaat ttttacttga
    14161 tgattttagt gaatcatatg aaccaggaga ttgtatagta gcattaccgc aaaacgaccc
    14221 tgaattggtt gaaaaactaa tatccatgtt aggttgggat ccgcaatctc cggtgccaat
    14281 taatgatcgt ggtgatacag ttcctattgt tgaagcacta acatcacatt ttgaatttac
    14341 taaattaaca ttgccattat tgaaaaatgc agatatctat tttgacaatg aagaattatc
    14401 tgaacgtatt caagatgagt catgggcgcg tgaatatgtt ataaatcggg actttataga
    14461 tttaataaca gattttccaa ctatagaatt acaacctgag aatatgtatc aaatccttag
    14521 aaaattacca ccaagagagt attcgatttc tagtagtttt atggcaacgc cagatgaagt
    14581 gcatattacc gttggtacgg ttcgttatca agcacatgga cgtgagagaa aaggtgtatg
    14641 ctcggttcat tttgctgagc gaattaaacc aggcgatata gtaccaattt atttgaagaa
    14701 aaatccgaac ttcaaatttc cgatgaagca agatataccg gttattatga ttggaccagg
    14761 tactggaatt gctcctttta gagcatattt acaagaacgt gaagaacttg gtatgactgg
    14821 aaaaacatgg ttgttctttg gtgatcaaca ccgtagttct gactttttat atgaagaaga
    14881 aatagaagaa tggcttgaaa atggaaactt aacacgcgta gatttagcat tttcaagaga
    14941 ccaagaacac aaagaatatg tacagcatcg tataatggaa gaaagtgaac gtttcaatga
    15001 atggattgag caaggcgcag caatctatat ttgtggcgat gaaaaatgta tggcgaaaga
    15061 tgtccatcaa gccattaaag atgtattggt aaaagaacgt catatttctc aagaagaagc
    15121 agagttatta ttgcgacaaa tgaaacaaca acaacgctat caacgtgatg tttattagcg
    15181 attggtgtta aatattttaa ggtgtaatga tgtaaaaaga tataaaggat gttgctcaac
    15241 atgaatatgc cattaatgat agatttaaca aataaaaatg tcgtcatagt tggtggaggc
    15301 gtcgttgcaa gtcgtcgggc acaaacatta aatcaatacg ttgaacatat gacggtcatc
    15361 agtccgacaa tcactgaaaa acttcaaaat atggtagata acggtgtcgt catatggaaa
    15421 gaaaaagaat ttgaaccaag cgatattgta gacgcgtatc tagttattgc agcaaccaat
    15481 gagccacgtg tcaatgaagc ggtaaaacaa gccttacctg agcatgccct ttttaataat
    15541 gttggagatg catcaaatgg caatgttgta tttccaagtg cactacaccg cgacaagcta
    15601 actatcagtg tatcaactga tggtgcgagt cctaagttga caaaatcaat tatggcagag
    15661 cttgaggcgt tatatccacc atcatacagt tcgtatatcg actttttata tacttgccga
    15721 cagaaaataa aagtacttga tataacatat aacgaaaagc aacagttact gtcacaaatt
    15781 gtgtcacaag aatatttaaa tcatgacaaa caagctcaat ttttagcgtg gttggatgta
    15841 agataataat agcggaccgt ctaaccgtct aaggtaagtc ttcttatttt aactttaacg
    15901 cttaatcatt gaaattaaga catgggtggc tttgtgaata gtctaataat gaaggattta
    15961 agcgataatg atatgcgttt taaatatgaa tattacaata gagaaaaaga tacgtagaac
    16021 aaacttaata aaatagatgg ataaattgaa atctggttga agtcgttact atcatagcga
    16081 cctttagcca gattttttgt gcaatagaaa gcaataataa aaatgataga tcaaaatgaa
    16141 atacaggaca ggatatacaa ggattagtca tgccatgtta tcaagtagga aaatcaaact
    16201 tcactattga tagttacgca aaaaagattt ttttgataaa atgagataac ttaaatataa
    16261 aaaattatat taattataat atttaagtta aagaggggga ttatgtaaat tgtattaaaa
    16321 gtggagggag aaaataatat gaatagtgat aatatgtggt taacagtaat ggggctcatt
    16381 attattattt caattgtagg tttactcatt gccaaaaaga taaatccagt tgtaggtatg
    16441 acaatcatac cttgcttagg ggcaatgatt ttaggatata gtgtgacaga tttggttgga
    16501 ttttttgcta aagggttaga tcaagtcatc aacgttgtta ttatgtttat ctttgccatt
    16561 attttctttg gcatcatgaa cgatagtggt ttattcaagc cgcttgtcaa acgcttaata
    16621 ttaatgacac gaggcaatgt cgtcattgtc tgtgcaatga cagctttaat tggcacaata
    16681 gcccaattag atggggccgg tgcggtaaca tttttgcttt ctattcctgc attattacct
    16741 ttatataaag cgttaaatat gaataaatat ttattgattt tactattagc attaagcgcg
    16801 gcgattatga acatggtacc ttggggaggt ccaatggctc gtgtagctgc agtgttaaaa
    16861 gccaaaagtg tcaatgaatt atggtatgga ttaataccta ttcaaataat aggtttcatt
    16921 cttgttatgt tgtttgcggt atatcttgga tttaaagaac agaaacgtat caaaaaagca
    16981 atagagagaa atgaattacc gcaaacacaa gatatagatg tacataaatt agttgaagta
    17041 tatgaacgag atcaagatgt aaggtttcct gtaaaaggac gtgcaagaac aaaatcatgg
    17101 ataaaatggg tgaatacagc tttaacttta gctgttattc tatcgatgtt aataaatatt
    17161 gcgccacctg aatttgcatt catgataggt gtctcattgg cgcttgttat taattttaaa
    17221 tcagtggatg aacaaatgga gcgattaaga gcgcatgcgc cgaatgcatt aatgatggct
    17281 gcagtgatta ttgcagcagg tatgttttta ggtgtactaa atgaaaccgg tatgcttaaa
    17341 gcgattgcga ccaatttaat caaagtgatt cctgcagaag taggaccata cttgcatatt
    17401 attgtaggtt tacttggcgt accattagat ttactaacta gcacagacgc ttattatttt
    17461 gctgtgttac cgattgtcga acaaacagca gggcaatttg gtgtaccgtc tgtatcaaca
    17521 gcttattcaa tggtcatagg gaatattata ggtacatttg tcagcccatt ttcaccagcc
    17581 ttatggttgg caattggttt agcagaggca aacatgggca cgtatattaa gtatgcattc
    17641 ttttggattt ggggattcgc catcgttatg ttagtaattg caatgttgat gggcattgtg
    17701 acgatttaag ttgcataaac atgtcgaaat gacagaacaa ttttaaaaat taatgaaata
    17761 attgtgtaga aatatgaatt tcactaaatg ttaataactt tgtgacgttt tagttaacag
    17821 actaataaaa atttgaaaat actatatata gtggtataac gtaatgagta gacacaatat
    17881 ataggaagaa ggggtaaaat gaatcaaatc gaagaagcat taacgggttt gatttctaaa
    17941 gatcctgcta ttgttaacga aaatgccaac aaagatagtg atacattttc aacaatgaga
    18001 gatttaacag caggtatcgt ttctaaatct tacgcattaa attatttatt accaaagcac
    18061 gttgcagatg cacatcaaag aggggacata cattttcacg acttagatta tcatccattc
    18121 caaccgttaa caaactgttg tttaatagat gctaaaaata tgctacataa tggatttgaa
    18181 ataggcaacg cgaatgtaac ttcaccaaaa tcaatacaaa ctgcatcagc gcagcttgta
    18241 caaattatag ccaatgtttc cagcagtcaa tatggtggct gtacggttga ccgcgttgac
    18301 gaattactta gtacatatgc acgacataat gaagaacaac atagaaatat cgcaaagcaa
    18361 tttgtcaaag aatctgaaat tgatcgttat gttgatcaac aagtcactaa agacatcaat
    18421 gatgcgattg aaagtctaga atatgaaatt aataccttat atacatctaa tggacagaca
    18481 ccttttgtaa cattaggatt cggcttaggt acagatcatt taagtcgcaa aattcaacaa
    18541 gctatcttaa atactcgtat caaaggctta ggaaaagacc gcacgacagc gattttccca
    18601 aaacttgtat tttcaattaa aaaaggaacc aactttagtc cgcaagatcc gaactatgac
    18661 attaaacaac tagcattaaa gtgttcaacg aaacgtatgt atccagatat tttaaattat
    18721 gacaaactcg tagaaatatt aggtgatttc aaagcgccaa tgggttgtcg ttcattttta
    18781 ccaagttgga aagatgcgga aggtcatttt gaaaataatg gtcgttgtaa tcttggtgtt
    18841 gttacactta atttacctag aatggcatta gaatctgccg gtaatatgac gaaattctgg
    18901 gaaatctttt atgaacgtat cgatgtgtta catgatgcat tactttatcg tataaatcgt
    18961 ttgaaagatg ctgtaccgaa taacgcacca attttatata aaagtggcgc ttttaactat
    19021 aaattaaaag aaacagatga tgttgctgag ttatttaaaa ataaacgtgc aacgatttca
    19081 atgggctata tagggttgta tgaaacagct actgttttct atggtccaga ctgggaaaca
    19141 tctcaagaag caaaagcatt tacgcttgaa attcttaaag aaatgaaacg ttatcaaacg
    19201 aaatggacag aattatatga catttggttc agtatttaca gtacgccgag tgaatcgcta
    19261 acggatcgtt tttgtcgttt agaccaagag agatttggag atattaaaga cattacagat
    19321 aaaggatatt atcaaaactc tttccattat gatgtacgta aagatgttac accttttgaa
    19381 aagttagatt ttgaaaaaga ttatccttat tatgcgagtg gtggtttcat tcactattgt
    19441 gagtatccga aattgcaaca caatttgaaa gcactagaag cggtatggga ctactcttat
    19501 gacaaagttg gttacttagg tacaaatatt ccgattgatc attgttatga atgtgattac
    19561 gatggagatt ttgaagcaac tgaaaaagga tttaaatgcc cgaactgtgg caatgataat
    19621 cctaaaacag ttgatgtcgt taaacgaaca tgtggttact taggcaatcc agttcaacgt
    19681 ccagtaatta aaggccgtca taaagaaatt tgcgcacgag taaaacatat gaaagcgcct
    19741 aaagaatgac acttttagac attaaacaag gacaaggtta tattgctaaa atagaatcaa
    19801 atagctttgt tgacggtgaa ggagtaagat gcagtgttta tgtatcagga tgtccattta
    19861 attgtgttgg atgttataac aaagcctcac aaaagttcag atatggcgag aaatacactg
    19921 atgaaatatt agcagaaata ttagatgatt gcgatcatga ttatatatct gggctaagtc
    19981 tattaggtgg cgaaccattt tgtaatttgg atattacatt aaatcttgtc aaagcatttc
    20041 gagcacgttt tggaaataca aagacaattt gggtatggac tggattttta tatgaatatt
    20101 tagcaaatga ttgtacagaa cgtcgagagt tattatcata cattgacgtt ttagtagatg
    20161 gtctatttat acaacactta ttcaaacctg atttaccata taaaggttct ttaaatcaac
    20221 gcattataga tgtacaacaa tcactctcgc atgcgcgtat gattgaatat atagttagtt
    20281 gaatatgtat tagaagtcaa ggtaacattc gttgccttgg cttcttttta ggttaggtac
    20341 ataattgaaa gttaataaaa gcaattcttt agaaaaatat attgatagaa tatgacctaa
    20401 caatcatttt gataccaata ctaaaagttg catatccgtt ttttaaaaaa gttgaaagaa
    20461 aaaagtggta ctttagtggg aaggaagtct aactttttgg tagcgtttta caataaataa
    20521 atattcgtta aaaacgtata aatattctta aatgccgtcc tagtaaaatt tgttaaattc
    20581 gttaaatcat aacttaacac agctgtttta gcgctattaa agttttgttt attacgagaa
    20641 aaattatata aatattcaat aattgccaag tttcaaattg tatgaaattt gcattattat
    20701 taaatattag ttattgtcaa ttttgtgaat caatataatt attacatttt gagataaatc
    20761 gaaacaggat tcataaaatt aataattagg gggagcacaa ttgaaaaaag agaaagttat
    20821 ggactggacg acctttatag ggacagtagc tgtacttctt tttgcagtta tacctatgat
    20881 ggcttttcca aaagcaagtg aagatatcat cactggtatt aatagtgcca tttctgattc
    20941 aattggttcg atatatttat ttatggggct ggcgattttt tgctttgtaa tgtatatcgc
    21001 atttggtaaa tatggtaatg tcacacttgg taaagcaagt gataaaccag aatttaatac
    21061 atttacatgg gcggcaatgc tgttttgtgc aggcataggc tctgatattt tatactgggg
    21121 cgttattgaa tgggcttttt actatcaagt tccaccaaat ggcgcgaaaa gtatgagtga
    21181 tgaagcactc caatatgcga cgcaatatgg tatgttccac tggggaccaa ttgcttgggc
    21241 tatttacgtt ttaccagcat taccaattgg ttatttagtg tttgttaaaa aacaaccggt
    21301 gtataaaatt agtcaagctt gtcgtccgat tttaaaaggt caaacagata aatttgtagg
    21361 taaagttgta gatatcttat ttatctttgg attgctaggt ggtgcggcaa catcactagc
    21421 gttaggtgtg ccattaattt ctgcaggcat agaaagatta actggtttag atggtaaaaa
    21481 tatgatttta cgttcggcta ttttattaac gattacggtc atatttgcta ttagttcata
    21541 tacaggattg aaaaaaggta ttcaaaagtt aagtgatatc aacgtttggc tatcatttgt
    21601 acttttagcc tttatattta ttattggacc gactgttttt attatggaaa cgacagtgac
    21661 agggttcgga aatatgttga gagatttttt ccatatggca acatggttag aaccattcgg
    21721 tggtattaaa ggtcgaaaag aaacgaattt cccacaagac tggacaatat tctactggtc
    21781 atggtggtta gtatatgcgc catttatcgg tttatttatc gctagaattt caaaaggtag
    21841 acgccttaaa gaagtcgtgc taggaacaat tatttatgga acgcttggat gcgtattatt
    21901 ctttggtatt tttggtaact atgctgtgta tttacaaatt tctggacagt ttaatgtaac
    21961 acaatattta aatacacatg gtacagaggc aaccattatt gaagtggtgc atcatttacc
    22021 attcccatca ttgatgattg tactattctt agtatctgct ttcttattct tagcaacaac
    22081 atttgattcg ggttcatata ttttagcggc agcatctcag aaaaaagtgg taggcgaacc
    22141 attacgtgcc aatcgtttat tctgggcatt tgcattgtgc ttattgccat tttcattgat
    22201 gctagttggt ggcgaacgtg cattagaagt attgaaaact gcttcaatac tggcaagtgt
    22261 gccattaatt gttattttta ttttcatgat gatatcattt ttaatcattt tagggcgcga
    22321 tagaattaaa cttgaaacgc gtgctgaaaa attaaaagaa gttgaacgtc gttcattgcg
    22381 aatcgttcaa gtatcagaag aagaacaaga cgataattta taattcaaat aatgatgcat
    22441 aagattttga attttataag tatataattg attgtcatat aaaacaaaaa cggtaatttc
    22501 tatttattga gatagaaatt accgtttatt tcgtggacct attgtattgt tttcatcatg
    22561 cataatcatc attgccgctg tccgaggcta attttaattt tcagaatcag aaggctgttc
    22621 tggaattggg aaatatttga aaatttcacc gctttcaatc gcttcggtta actgttctaa
    22681 ccattcgtaa taaacatgtg tatgatcaag ctgagcttta attttttgtg cctcttgtgt
    22741 ttcagcttca gttaaatcac tgctttcaag taatggattg ataatagctt gagcatcttt
    22801 tactgcttcg acattgatgt caatttcacg ctgaaatttt ttagtgaaaa agtttcggaa
    22861 aaagatgaaa aagtctttct cggcgataaa atgttgtttg cggcttcctc tcgtaaattg
    22921 ttgtttaaca atatcaaatt cctgcaattt cttaacgcca gcactcatac ttggtttgct
    22981 catttgcaat tgatgacgca tttcatcaag cgtcatactg ccttcaaaca ccatagtgcc
    23041 atataagttt cctacacttc tattagtgcc atacaaatcc attgtctgtc caattgaatt
    23101 aattacaata tcttttgctt gttctaattg ttgctgtttg ttctgagaac gagtcatcat
    23161 tgcacctccg tacatcattt tgttcacgtt aaaataaata ctaatacatt ataaaacctt
    23221 ttctaaaaaa agacattaaa aatatttaaa gcattaaagt taaatgtttc gttaaataaa
    23281 aatctaacga acttacaaaa cttaattctt gagttgtttt gtaaattgac acatttttca
    23341 tttctatgct aacataagtt tgtaaaattc gttaaataaa aatttaacaa acttaacgga
    23401 ggttgttgaa tggaactttt aaaacattta tctcagcgtc aatatattga tggtgagtgg
    23461 gttgaaagca cgaataaaaa tacaagagat attatcaatc cttacaatca agaagtgata
    23521 tttacggttt ctgaagggac aaaagaggat gcagaacgtg caatcttagc tgcaagacgt
    23581 gcgtttgagt ctggtgaatg gtcgcaagaa actgctgaaa aaagaggtaa aaaagtacgt
    23641 gccatcgcgg acaagatcaa agaacatcgc gaagcgttag cacgattaga aacattagat
    23701 actggaaaaa cgttagaaga atcatatgca gatatggatg atattcataa tgtgtttatg
    23761 tattttgctg gattagcaga taaagatggt ggcgaaatga ttgattcacc aattccagat
    23821 acagaaagca aaattgttaa agaaccagta ggtgtagtta cacaaattac accttggaat
    23881 tatccgttat tacaagcatc atggaaaatt gcgccagcgc ttgctacggg ttgttcacta
    23941 gttatgaaac caagtgaaat tacaccatta acaacaatac gtgtttttga attaatggaa
    24001 gaagttggtt tccctaaagg aacaattaat cttattctag gtgcaggttc tgaagttggt
    24061 gacgtaatgt caggtcataa agaggttgac cttgtatcat ttacaggtgg cattgagact
    24121 ggtaagcata ttatgaaaaa tgctgctaat aatgttacga atattgcctt ggaacttggc
    24181 ggtaaaaatc caaacattat ctttgatgat gctgattttg aattggcagt agaccaagcg
    24241 ttaaatggtg gatattttca tgcaggtcaa gtttgttcag caggatcaag aatattagta
    24301 caaaacagta ttaaagacaa atttgagcaa gcacttattg atcgcgtgaa aaaaatcaaa
    24361 ttaggtaatg gttttgatgc tgatactgaa atgggaccag tgatttcaac agaacatcgt
    24421 aataagatcg aatcttatat ggatgtagct aaagcagaag gcgcaacaat tgctgttggt
    24481 ggtaaacgtc cagatagaga cgatttaaaa gatggtctat tcttcgagcc aacagtcatt
    24541 acaaattgtg atacgtcaat gcgtattgta caagaagagg ttttcggacc tgtcgttact
    24601 gtagaaggct ttgaaactga acaagaagcg attcaattag cgaatgattc tatatatggt
    24661 ttagcaggtg ctgtattttc taaagatatt ggaaaagcac aacgcgttgc taacaagttg
    24721 aaacttggaa cggtgtggat taatgatttc catccatatt ttgcacaagc gccatggggt
    24781 ggatacaaac aatcaggtat cggtagagaa ttaggcaaag aaggcttaga agagtacctt
    24841 gtttcaaaac acattttaac aaatacaaat ccacaattag tgaattggtt tagcaaataa
    24901 aaattagata aggtgagtgc cattgtaaga acacaagaca ctcactttgt tttgtataag
    24961 tggcgaaatg ttgattgata atttggacta aacgcaaaat gaatcataga ttatttcatg
    25021 actgttagta acaatcgtaa aaggaaaatc gagtgttttg gttagccaag tttagcaatt
    25081 caacgataac caatcagcca ctaacaaata tttcatgcaa tactcacttt gaaatacaac
    25141 aaactttgga ggtcataacg atgagtaaca aaaataaatc atatgattat gtcatcattg
    25201 gaggaggcag tgcaggttct gtactaggta atcgtctgag tgaagataaa gataaagaag
    25261 tcttagtatt agaagcgggt cgcagtgatt atttttggga tttatttatc caaatgcctg
    25321 ctgcgttaat gttcccttca ggcaataaat tttacgattg gatttattca acagatgaag
    25381 aaccacatat gggcggtcgt aaagtagcac atgcccgagg taaagtttta ggtggatcaa
    25441 gttcgattaa tggcatgatt tatcaacgtg gtaatccaat ggactatgaa ggctgggcag
    25501 aaccagaagg tatggaaact tgggattttg cgcactgttt accgtatttt aaaaaattag
    25561 aaaaaacata cggtgcagcg ccttatgata aatttagagg ccatgatgga ccaattaagt
    25621 taaaacgagg gccagcaacg aatcctttat tccagtcatt ctttgatgca ggtgttgaag
    25681 caggttatca taaaacacct gatgtgaatg gatttagaca agaaggtttt ggaccgttcg
    25741 atagtcaagt acatcgtggt cgccgaatgt cagcttcaag agcatattta catccagcaa
    25801 tgaagcgtaa aaacttaacc gttgaaacac gtgcctttgt aactgaaatt cattatgaag
    25861 gtagaagagc aactggtgtt acgtataaga aaaatggcaa actacatacc atcgatgcta
    25921 atgaagtcat tttgtctggt ggggcattca atacgccaca attactacaa ttatctggta
    25981 tcggtgattc agagttccta aaatcaaaag gcattgagcc acgtgttcat ttaccaggtg
    26041 tgggtgaaaa ctttgaagat cacttagagg tatacattca acataaatgt aaggaacctg
    26101 tatcattaca gccaagctta gatatcaagc gcatgccatt tattggttta caatggattt
    26161 tcacacgtac aggtgcagca gcatctaacc attttgaagg tggcggattt gtacgttcaa
    26221 ataacgaagt tgattatcct aacttaatgt tccatttctt accaatagct gtaagatatg
    26281 atggtcaaaa ggcagcggtc gcacatggtt atcaagttca cgtaggacca atgtattcaa
    26341 actctcgtgg tagcttgaaa atcaaatcta aagatccatt cgaaaaacca agtatccgct
    26401 ttaattattt atcaacagaa gaagataaaa aagaatgggt agaagcaatt cgtgtagcaa
    26461 gaaatatctt atctcaaaaa gcaatggatc cattcaatgg tggagaaatt tcaccaggac
    26521 cagaagtgca aacagacgaa gaaattcttg attgggttcg tagagatggt gaaacagcat
    26581 tacacccatc ttgtagtgct aaaatgggtc ctgcttcaga tccaatggca gtagttgacc
    26641 cgttaacaat gaaagtccac ggtatggaaa atttacgtgt agttgatgca tccgctatgc
    26701 cacgtacgac aaatggcaat atacacgcac ctgttttaat gttagctgaa aaagcagcag
    26761 acattatacg tggcagaaag cctttagagc cacaatatat tgattattat aagcatggtg
    26821 ttcatgatga aaatgaaggt gcaatcgaag taaaaccata cgctaaataa atttatatag
    26881 tagactctta gtctggcatc tattgtattg gtgccagact tttttgcgtt ttatctaaat
    26941 gagaagttaa tgtgttgttt aaaaacggtg tgtgagtaag tgaactgaaa atagagttaa
    27001 ttgtacattg tgatgattaa ttgacctaat tggcagacat taaaagagtg tacaacctta
    27061 aaaagttcac taaatagaca tttaattgtg ttttcttgaa agctttcgtg gtaggattta
    27121 tataagtaaa ttgagagaag gaatactatg agcttttacg aatatataca aacatttaaa
    27181 gatgataaaa caccattagg cgaattagcg atttggatta aagaagatga ttcattccca
    27241 aaacaagaga agctaacaga aaacattttg tcttattttc atcaaatgtc caatatagat
    27301 catgagtttt tagaaattgt aaaaagatca ctttctctgt atgatcaatt aaaatcgtaa
    27361 aatcagaaat aaagttagct aaaataaaag gccggtgatt tcacagatga agttgtcggc
    27421 tattttcatg actaatgtta aataatgatc atgaaattga agacacaaaa atagtgggcg
    27481 actcctgtcc ccatttgcat gaaatattaa tactttttac aaagtcttat cttttaaaaa
    27541 gaagccaaac tatgattgta attaataaat acgggaatga attagtcata gatataaagt
    27601 aatatgacca aaaatataaa tgaaatgaag gcatttatta tgaacattta tgatgaatat
    27661 agaagttatt taatagaaga actggatgat tgtctcacaa tacaaaaaaa taatgacact
    27721 gcatattacg atgtgctaga agcgataaat gatttatcaa atgattcatt atgtgtgtta
    27781 aatcatttat atattaacga aggacaagaa gaaacattcg agcaaaaatt tttgcaacgt
    27841 aataagcatt taaaaaacgt tgatgggttt aaagcattaa ggtttttaag acctagaaca
    27901 gctggtagac actatatcat tattacgctg tgggaaaata ggcaagcatt ttatcattgg
    27961 caaaattcag ctgagtacaa gcatacacac aagcatcgtg gcacttcgaa aggtgcagat
    28021 gtaaaaataa ttaatcgtga attatcatac aatattcgta ttgaattagc tgatatggtc
    28081 tagcccgaga tatcaaccct caatcatttg aaagtccttg aatgctacgt catggcaaag
    28141 tgtagtgccg aggactttgg tatttaaccc tatttaattg aaaattctgt aaagataggc
    28201 gtatgatata tataattcat ttataaaatt acaatgttca tcacagggaa agtggatgta
    28261 tgaaaggaag ttagttatgc aaaagtcagc tctattcgcg cctgaaaaat ataacattat
    28321 ttcggaaatc gaaaaatata gccacatacc agataaaaag gcaattttat atcataatac
    28381 tgaaggcgaa gatatatcag tcacttacca acagctcatt gaacagtcta ataaagtagg
    28441 taatgtttta gcatcgcacg gtttatctaa aggcgataaa gtactcatta tgatgccacg
    28501 atctattgcg acgtatgaat tatatattgc tgctttaaaa ttaggtgttg caatcattcc
    28561 atgttctgaa atgctaagaa ctaaagattt acaataccgt atcacgcacg gtgaaataaa
    28621 tgcagttatt gcactagagc cattcacagt tgaatttgaa aaaattaaag aatatgatgc
    28681 gttaactaaa tttgttattg ccggtcaaaa agatggatgg atttcacttg aagctgaaaa
    28741 agaaaacgca agtaacaaac tagaaatggc agatacgacg cgtgatgata tggcgattct
    28801 gtcatataca tctggtacaa ctggcaatcc taaagccgtt acacattgtc atggatgggg
    28861 atttgcacat ttacaaatgg caccaaaaca ttggttatgt attaatgaag atgacttagt
    28921 ttgggcaaca gcagcaccag gttggcaaaa atgggtatgg agtcctttct tatctgtatt
    28981 aggttcaggt gcaactgctt ttgtatttaa tggaaggttc agtcctgaaa catacttaga
    29041 attgcttcaa aaatatcaaa ttaatgtttt atgttgtaca ccgacagaat atcgtatgat
    29101 ggctaaatta cagaacttaa atgattatga cttaacgcat ttacatagtg ccgtttctgc
    29161 aggtgagcca ctaaatcgag aagtagttga acaattcaag aaatacttta atttaactgt
    29221 aagagatgga tatggccaga ctgaaagtac cttgcttata ggctttttaa aagatacacc
    29281 acagaggatt ggatcaatgg gtaaaggcat tccaggtagt tcggtcactg tagtagatga
    29341 tgaggggaat agcgtacctg ctaatacgaa agggaatatt gcagtaccac ttgatttgcc
    29401 agcacttttc aaagggtatt ataaagagcc agaacgtacg gcgaaagcgc aaacaggtaa
    29461 atactacatc actggtgact tagctcatgt agatgatgat ggttatttct ggtttgaagg
    29521 acgtcgagat gacattatta ttagttcagg ctatacgatt gggccttttg aagttgaaga
    29581 tgcgttaacg aatcatccag ccgttaaaga atgtgctgta gtagcaaaac ctcatgatat
    29641 acgaggaaat attgttaaag cattcgttat tttacaggac catactgcgg gtgatgatat
    29701 gttagttaaa gaactacaac aatttgttaa aaatgaagtt gcaccatata aatatccgag
    29761 agagattgaa ttcgttgacg acttaccaaa aacaaactca ggtaaaattc gtcgtgttga
    29821 actacgagat tctgaaatag aaaaatggca acaacaaaaa gatagcaatc aataaacata
    29881 gcaaagcagt ccaatgcgta aggtatgatg atacgcactg gactgcttgt ttatttatga
    29941 tgttctttgt cgtctagtta taaatattaa aattagttta gaaacaagcg caaccagtat
    30001 taagaatgag aaaatataag atgttaaacc tcgaatatcc cagtttaata aaaacacatt
    30061 actatcaccg gcattaagtt gaaactcagt atgtgttaga acgataatta caatacctat
    30121 aagtgcaaga ttcaaaataa ttttcaatat taaaggtaat tgtaatgttt ttcttggatg
    30181 cagatattga atctcctttt tatgattgat tttacactta tattgtatca aaatagagta
    30241 taggtttaaa atgctataag ccaaatgtag attaaaacaa tcgttagcta tttgttgtca
    30301 aataattatg attgatttga tatttatctt ctatgaataa aagatttaat atattgcaaa
    30361 gttaatgaat aattataatt tacatttacc actgcttgct ttaacatata catgtaagca
    30421 ctaactatag tattttgtta cagcgtatca attaaaacag gaagttatct atggcgttga
    30481 tattttaaag aaatatgtca gttttatgta actttcatat tgatgataca catttacaat
    30541 ttttggagag gtgaaaccaa tggctaagtc taatagtaaa gacatcgttt taattggagc
    30601 cggtgtactt agcacaacat ttggttcaat gttaaaagaa attgagccag actggaatat
    30661 ccacgtttac gaacgcttgg atcgtcctgc aatcgaaagt tcaaacgaaa gaaataatgc
    30721 tggtacgggt catgcagcat tatgtgagtt gaactacaca gttttacaac ctgatggttc
    30781 tatcgacatc gaaaaagcga aagtgattaa cgaagagttt gagatttcaa aacaattctg
    30841 gggtcactta gtgaaaagcg gtagcatcga gaacccaaga gaatttatca atccattacc
    30901 acacatcagt tatgttagag gtaaaaacaa tgttaaattc ttaaaagatc gttacgaagc
    30961 gatgaaagct ttccctatgt tcgataatat cgaatatact gaagacatcg aagtaatgaa
    31021 aaaatggatt ccattgatga tgaaaggccg tgaagataac cctggtatca tggcggcaag
    31081 taaaattgac gaaggtacag atgtaaactt cggtgaatta acacgtaaaa tggctaaaag
    31141 cattgaagca catccaaatg ctacagtgca atttaaccat gaagttgttg attttgaaca
    31201 attatcaaat ggtcaatggg aagttactgt taaaaatcgc ctaactggtg agaaattcaa
    31261 acaagtaact gactatgtat tcatcggtgc tggcggtgga gcgattccat tattacaaaa
    31321 aacaggtatc cctgaaagta aacatttggg tggattccct atcagtggtc aattcttagc
    31381 ttgtacaaac ccacaagtta ttgaacaaca cgatgccaaa gtttatggta aagagccacc
    31441 tggtacacca ccaatgactg tacctcattt agatacgcgt tacattgatg gtcaaagaac
    31501 attattattt ggaccatttg ctaatgttgg acctaaattc ttgaaaaatg gttctaactt
    31561 agatttattc aagtctgtta aaacatacaa cattacaact ttattagcag cagcagttaa
    31621 aaacttacct ttaattaaat actcatttga tcaagtgatt atgacaaaag aaggttgtat
    31681 gaaccactta cgtactttct atccagaagc acgtaatgaa gattggcaat tatacactgc
    31741 tggtaaacgt gtacaagtta tcaaagatac acctgaacac ggtaaaggat tcatccaatt
    31801 cggtacagaa gtggttaact cacaagacca cactgtaatt gcattattag gtgaatcacc
    31861 aggggcttca acttcagttt cagttgcgtt agaagtatta gaacgtaact tccctgaata
    31921 caaaactgaa tgggcaccta aaatcaagaa aatgattcca tcatacggtg aatcattaat
    31981 tgaagacgaa aaattaatga gaaaaatccg taaacaaact tcaaaagact tagaattagg
    32041 ttactacgaa aactaaattc taatagctat atttaaaatc ggacaactga gaaatcttaa
    32101 agatttttca gctgtccgat ttttttacgt aatctaatac atacggcaaa ttcaacttta
    32161 atcaaaaaag actcatacac aatgccctta aagcacatgt atgagtcctt tttagtagtt
    32221 tatatcaaaa aatacgttta atgtataaat tagtttttgt ttacagatgc gtcgtagatt
    32281 gattctacag catcacctaa agctttatcg aattcttctt tagattgatc agctcttaaa
    32341 tcactagcta atgcacgtga gaaacttgcg ataagttcat cgttatcttt aagtaattca
    32401 tttgcttttt ctctgctgta accacctgat aatacaacga cacgaacaac attaggatgt
    32461 tcagctaact ctttgtataa gtttggttca gtaggaattg ttaatttcaa cattactaat
    32521 tgatcagcat ttaagctatc taaacctttt ttaagttcag cttttaatac tttttcaatt
    32581 tcagctttgt cttttgcatt aatattaact tctggttcga taattggcac taaaccttta
    32641 gcaataattt gtttagcaac ttcaaattgt tgttcaacaa cgtctttgat accttgctca
    32701 tttaattcta aaatgttaga acgcattttt gtaccaaaaa tgtgacgttc gtttgcacgg
    32761 tctaataaac tgtctaagtt gtcgattggt ttcattaatt gaacaccatt ttgctcttca
    32821 gcaagacctt tgtctacttt taagaacgga acaacacctt tatcagctaa gtaatctgca
    32881 gtgtatttgc cttctacttc gcgatccatt gtttgttcga aaagaatagc acccaaaatt
    32941 ttatctggtg agaatgaagg tgaagttacc acacgtgtac gcatatcgtg aacaagttgg
    33001 aacatttcgt cttcattgct atattgatct tcgtttacac catattcttt aagtgctttt
    33061 ggtgtactac caccactttg gtctaatgcg gcaataaagc cttttccatt tttcattttt
    33121 tctaattgct ctttattcat actttccact ccttaacttt tcaatacacc tccagtatga
    33181 taaaaatgag aacatttctc aagtcataaa ccttgaaaag tgtataaaat gtgaaaaata
    33241 attgtcagtt taattaaaaa tattatttta ttctaggtat gactaacgcc attaatgaca
    33301 taaagaaaat atgtgtaata atccaaccga ttaattctgt cacactaaat tgaaaaattg
    33361 gacgttgcgc aataaatact aaaaagggat acaatgctat aaataagaaa aataaaggga
    33421 tataacatag atagtaaagc cttttagaag tatgaaacag caacacaaat acaaaataaa
    33481 tgacgctacc aattagtaag tgacatatta tttctagaat atatggtgta ttgtcagaag
    33541 gaattagaaa atctaaattc aataataaag cttttaaatg tgattgattg cttattaagt
    33601 caaacaacat ggtcatccat agcaacatga atgatatgaa aatagcagca atgaaatgga
    33661 acaatacttt taaacgcatt cgtatcacct cagagtcaaa tggaatatag taaacaattc
    33721 cctaatcgaa caaaattatg cgcataaaca aagtagattg atataaaatt cttaattatc
    33781 agaatatatt tacaaatctg aattttatta gtatattgga tagtattcat agaggcatga
    33841 cggtatttga gcaggatttt aaatcggatt ttataatcga tttaagagag gccactttgc
    33901 ttgcacatta atactgtcaa tgggagggga atgtatatga gtaaagcaca tcaattaatt
    33961 caagaggatg aacattattt tgcgaaatca ggacgtatta aatattatcc gttagtgatt
    34021 gatcatggat atggagcaac attggttgat attgagggga agacatatat cgatttgtta
    34081 tcgagtgcaa gttctcaaaa cgtaggtcat gcacctagag aagtaacaga agcgataaag
    34141 gcacaagttg ataaatttat tcattataca ccagcatata tgtatcatga accgttggta
    34201 cgtttagcta agaagctttg tgagcttgca cctggagatt ttgaaaaaag agtgaccttc
    34261 ggattaaccg gatcagacgc aaatgatggc atcattaaat ttgccagagc atatacaggg
    34321 cgtccttata tcattagttt cactaatgca tatcatggtt caacttttgg ctcattgtct
    34381 atgtcagcta ttagtttaaa tatgcgcaaa cattatggtc cgttattgaa tggtttttat
    34441 catattccgt ttccagataa atatcgtggt atgtacgagc agccacaagc taattcagta
    34501 gaagaatatt tagcaccctt aaaagaaatg tttgcgaaat atgtacctgc tgacgaagta
    34561 gcatgtattg ttattgaaac gatacaaggc gatggtggac ttttagaacc agttccaggg
    34621 tattttgaag cgttagaaaa gatttgtcgt gaacatggta ttttaatcgc tgtcgatgat
    34681 attcaacaag gttttgggcg aacaggtaca tggagttcag tctcgcattt taattttacg
    34741 cctgatttaa tcactttcgg aaaatcctta gcaggtggta tgcccatgtc agcaattgtt
    34801 ggacgcaaag agattatgaa ttgtttagaa gcaccagcac atttatttac aacaggtgct
    34861 aatccagtta gttgtgaagc tgcattagcc acaattcaaa tgattgaaga tcagtcgctt
    34921 cttcaggcta gtgcggaaaa aggggaatat gttaggaaac gaatggatca atgggtatct
    34981 aaatacaata gtgtaggcga tgttagaggt aaaggtctga gcattggtat tgatattgtt
    35041 tccgacaaaa aactcaaaac acgtgatgcc agtgcggcac ttaaaatttg taattactgc
    35101 tttgagcatg gcgtagttat tatagctgta gcaggaaatg tgttgcgatt ccaaccgcca
    35161 ttggtgataa catatgagca attagacacg gcgttaaaca ctatagaaga tgcactgact
    35221 gctttggaag caggtaactt agatcaatat gacatatctg gacaaggttg gtaatagcga
    35281 ttatcttaat ataaaataaa aaatcatttc cacatctgga tgttaatcag atgggaaatg
    35341 atttttttga ttttttattt tggtgggtgg tattcagcta catcattttt cttagaatgt
    35401 ctaagtccat aacttaaata tagaatgata ccaacaataa accaaattaa agtgtataat
    35461 ttcgcttcga atcctaatcc ccagaatact agcaatacta aaacaaatgt aattgctggt
    35521 aacacaggat ataaaggtaa tttaaatgca ggaattggta gatctttacc ttcacgcttt
    35581 ctcaaacgat acattgctaa tgaaacgaac ataaatgcaa caagtgtacc tgctgaaatt
    35641 aattgtgcta aaaatgcgaa tgggaacata gaaccaatta aaacaccaat aatagtaagt
    35701 ataactagtg cgcgattagg taaatgtttg tcgtttaaat ggcttaacca tgaaggtaat
    35761 aagccgtcac gtccaaatga ataaagtaaa cgtgagcctg ctaacatcat accaattaat
    35821 gctgtaaaca taccgataac agagatagct tgaacaatag ctgctacaac accatgacca
    35881 ctttgacgta aagcccaacc aacaggttca gcattgtttg cgtattgtga gtaatggaac
    35941 ataccaacta acacaagtgc tacagcaata aataatacga tagcaacact taaagaacca
    36001 agaatacctc taggcattgt cttttgaggg tcaagtgctt ctgctgagtt tgctgcgata
    36061 gaatcgaaac cgatatacgc taagaaaatc attgaaacac cagcatatat gccttgccat
    36121 ccaccaaagt cacctgtagc agttactttg tgttctggaa taaatggcac atagttacta
    36181 acatttattg ctgttaaacc tacgatgaca aataaaataa tagctaatac ttttaaaata
    36241 actaaaatgt tttccatacg tgctgcttct gacataccac gtgatagtaa taatgcagtt
    36301 aataaaataa cgatagcagc aataatatcg ataaaaccgc cattcgtacc aaatggattt
    36361 gataatgctg caggtaattc gatgccaatt ggtttcacaa gtccgcgtaa attcgctgag
    36421 aatcctgatg caacaaaggc tacggcgata aaatattcag ctaatagagc ccaaccggca
    36481 acccatccaa aaaattcacc aaataataca ttgacccaag aataggctga acctgcaaat
    36541 ggcatagcgg cagccatttc tgcataagta aatgcaacta aaccagcaac aatagcagcg
    36601 agtaagaatg ataacgcaac ggccggtcct gcatgttctg cagcaacaat gccaggtagc
    36661 gtaaagatag atgtcgatac aattgttcct acacctaaag ctaagaaatc acgcacccga
    36721 agtgtacgct ttaaatgacc atctttattt tgatagatag ccggatcctc ttttcgtgct
    36781 attttattga aaaaacttcc cataaacttt cctcccaaac attcataaac aattctatac
    36841 ggtgtttttt aatatgttat atcatagcac aaataatcaa tattttgtct aaaaattctg
    36901 aaaaatcaca actttatgtt acgtattaat gacttgtctt gataacatcc atagattttt
    36961 taaatgataa aactgattat aacagatatt aaatgaataa gtactatttt tgctaatttt
    37021 ctaacaattt tgcacattat atttttaaaa tcaatttcat gtttatgtct gattggctag
    37081 tttgtatgaa atgtaattct ttgactataa aatgatgcat caaatatgat gagggtaagg
    37141 cggaaaatag gaggttatat agtaagtcat ttaagtcgaa tagccatcct ttttaaaatg
    37201 aaaaaaatag aaagctcaat agtttgttaa aggctttaaa tagcgtcatt acgcaatttt
    37261 agaatgctaa aaattgtcac aaatttcaaa ttacgtgcta aagcttgaga tatcaatatt
    37321 tattggcgat agagtgtaat ttgactccgc ttacatctca gttttatgtt tgtaatttgg
    37381 tagcataata ttataataaa ataaaattgt taatctttaa tttcagtata gatattttta
    37441 cgtgtagtca cgtgtaaaat aaattcaatt aggttaggag acataattat gaaaacattt
    37501 ggtaaaaagg ttgtattaat cggagatgga tctgtaggat caagctatgc ctttgcaatg
    37561 gttacgcaag gtgttgctga tgaatttgta attattgaca ttgcaaaaga caaagtaaaa
    37621 gcagatgttc aagatttaaa ccatggtaca gtccacagtc cttcaccagt tgatgtgaaa
    37681 gcaggtgaat acgaagactg taaagatgca gatttagttg ttattacagc tggtgcacct
    37741 caaaagccag gtgaaacacg tttacaatta gttgaaaaaa atactaagat tatgaagagc
    37801 attgttaaga gtgttatgga tagcggcttt gatggatatt tcttaatcgc ggcaaaccct
    37861 gttgacattt taacaagatt tgtaaaagaa tatactggtt taccagcaga gcgtgttatc
    37921 ggttcaggta ctgtattgga cagtgcacgt ttacaatatt taattagcca agaacttggt
    37981 gttgcacctt caagtgttga cgctagtatt attggtgagc atggtgatac tgaacttgca
    38041 gtttggtcac aagcaaatgt agcaggtatt tcagtatatg acacattaaa agaacaaact
    38101 ggtagcgaag ctaaagcgga agaaatttat gtaaatacac gtgacgctgc ttatgaaatt
    38161 atccaagcta aagggtcaac atactatgga attgcattag cattgatgcg catttcaaaa
    38221 gccattttaa ataatgaaaa taatgtctta aatgtttcta tacaattaga tggtcaatat
    38281 ggtggtcaca aaggcgttta cctaggtgta ccaacattag ttaaccaaca tggcgcagtt
    38341 aaaatttatg aaatgccatt aagtgccgaa gaacaagcgt tgttcgataa atctgttaaa
    38401 atattagaag atacatttga ttcaattaaa tatttattag aagactaagc ctattttaag
    38461 tattaattag aaatatatta atggtaagag gatctattag tgttgcagta acatgtggca
    38521 ctgatagatc cattttttta gcaagcattg atagaggcaa tacttttgcg taaaataata
    38581 attgaataaa gtattatgac tcgtgaaaat ttagtgacat gaatcgaaat gccgaggcgt
    38641 cattgagtat aaaggaaagt agttctgcat taagcacgaa gtagagcatg acaacgagga
    38701 ataactatag ggagatggtt ttggaatgac gaatgtcttg tatcaacatg gtacattagg
    38761 tacgttaatg gctggcttac tagaaggaac agctacaatt aatgaattgt tagaacatgg
    38821 gaatttaggg attgcaacgt taacagggtc tgatggcgaa gtaatatttt tagacgggaa
    38881 ggcatatcat gctaacgagc ataaagaatt tatagaatta aaaggcgatg agaaagtacc
    38941 gtatgcatcg attactaatt ttaaagcgag taagacattt ccattgcaac aattatcaca
    39001 agatgatgta ttcgcacaaa ttaaaaatga aatgttaagt gagaatttat tttcggctgt
    39061 taaaatttat ggcacattta aacatatgca tgtacgaatg atgcctgctc agcaaccgcc
    39121 atatacacgt ttgattgatt cagcacgcag acaacctgag gaaaaaagac aagatattcg
    39181 tggtgccatt gttggatttt ttacaccaga attatttcat ggcgtagggt ctgctggttt
    39241 tcatatacat tttgcggatg atgaaagagc ttatggtgga catgttcttg aatttgaagt
    39301 ggatgacgtt gtcgttgaga tacaaaactt tgaaacattc caacaacatt tcccggtaaa
    39361 taacgagacg tttgttaaag cgaaaataga ctataaagat gtggcagaag aaattagaga
    39421 agctgaatag tctaatataa ttaaaagacc ttagcgatat taggaacagg tggttctaaa
    39481 tgcatcgtta aggtcttttt atattatata tgtgcttaca tattttgttg ataagcgcgt
    39541 aaaaagctat aaatagtatc aagatatggg gtgtcaagat tgtgttcacg tgcacgtcga
    39601 taaataaagc cttgaatcgc ttcgacttca agaggttgct gatgcacaat gtcgtaatac
    39661 atgctcgttc ccatttcgtc gggataacct tgatatatag tcataatagt atcgacagtt
    39721 tgttctgaaa agtttaaccc ctctgcctgt gcaacacgac aaccatctag taataactgt
    39781 ctacacagta tacgtatttc aggattatgc atgattgcaa ctgtctgtct cccgagtgct
    39841 gtgatagaat taatgcccaa gttaactaac aatttatacc aaatagcttg ttgaatattt
    39901 gcttctaata caatgtcgat ttgactgtct tggaccaaat ctctaaattg tcgagttaat
    39961 gcattatctt gtatacgtaa ttgataatct ctgaagtgcg taacaacatc gcctttcttt
    40021 tgaccactta tatagacaac tgcttggcat acatttttaa atggaatatg ttcgagttga
    40081 ccataaccat tttgggctaa aatgatgagc gtgtcctcat gtgcaagata agttaaatga
    40141 ggaataacgg catcaagttg atgtgttttg actgcaataa taataacatc aaatgtgttt
    40201 gtgacatctt cataaccttt cacaacaata tcttgtgcag gtgcatgtgg tacagtataa
    40261 tatgttattg ttttggcgtg tctcccgata agcgttgtat gaggcaatga ttgttgtaat
    40321 tcataggcaa tagttgtacc gacagcgcct gggccgataa tcgcaactga taacatcttc
    40381 ttctttcctt tctataaaag attcattata ctatttctaa taatactgca aaaagaggtt
    40441 gaataacatt gaaaacagta agtcaattaa tagatatgaa acaaaagcaa actaaaattt
    40501 ctatggtaac agcttatgat tttccaagtg ctaaacaagt ggaagcagcg ggtattgata
    40561 tgattcttgt tggggattca cttggtatga ctgtattagg ttatgaaagt accgtacaag
    40621 tgacgttagc agatatgatt catcacggtc gtgcagtaag aagaggcgca ccaaatacat
    40681 ttgtagttgt tgatatgccg attggtgcag taggcatctc tatgacacaa gacttaaatc
    40741 atgctctaaa gctttatcag gagacgaatg caaatgcaat taaagcagaa ggagcgcata
    40801 ttacaccatt tattgaaaaa gcaacggcaa ttggtattcc tgttgttgca catttaggat
    40861 taacacctca aagtgttggc gttatggggt ataaattaca aggtgcaacg aaagaagcag
    40921 cggagcaact tattttagat gcgaaaaatg tagaacaagc tggtgcagtt gcgttagtac
    40981 ttgaagcaat tccaaatgat ttagcagagg aaattagcaa gcacttaaca attccagtca
    41041 ttggtattgg tgcaggaaaa ggtacagatg gtcaagtatt ggtttatcac gatatgttaa
    41101 attatggtgt tgaacataaa gcgaaatttg tgaagcaatt tgctgatttt agtgttggtg
    41161 tggatggttt aaaacaatac gatcaagaag ttaaatctgg tgcatttcca tcagaagaat
    41221 atacgtataa aaagaaaatt atgaatgagg ttaataacaa tgactaagct gattactacg
    41281 gtaaaagaga tgcaacacat tgttaaagca gccaaacgct caggaacaac gattggtttt
    41341 atcccaacaa tgggtgcctt acatgatgga catttaacga tggtacgcga atcagttagt
    41401 acaaatgata ttacagttgt gagtgtattt gttaatccat tacaatttgg tccaaacgaa
    41461 gatttcgatg cttatccgag acaaattgat aaagatttag aattagtatc agaagtaggg
    41521 gcggacattg tttttcatcc tgcagtagaa gatatatatc caggtgaatt aggtattgat
    41581 gtcaaagtag gtccattagc tgatgtgtta gaaggagcga agcgtccagg gcattttgat
    41641 ggggtggtaa cagtagttaa taagctattt aatattgtta tgccggatta tgcttatttt
    41701 ggtaaaaaag atgcccagca attggctatt gtcgagcaaa tggtaaaaga cttcaatcat
    41761 gccgttgaaa ttattggtat tgatatcgtt cgagaagcag atggtttggc gaaaagttca
    41821 agaaatgttt atttaacgga gcaagaacga caagaagcgg tacatttaag taaaagtttg
    41881 ctattagcac aagcgttgta tcaagacggt gaacgtcaaa gtaaagtaat tatagacagg
    41941 gttactgaat atcttgaatc acatataagt ggacgcattg aagaagttgc tgtttatagt
    42001 tatcctcaat tagtagaaca acacgaaata actggacgca tatttatctc gttagctgtc
    42061 aaattttcaa aagcgcgttt aatagataat ataataattg gagctgaata aagtgataag
    42121 aacaatgatg aatgctaaaa ttcatagagc aagagtgact gagtcaaatt taaattatgt
    42181 aggtagtatt acgattgatt cagatatttt ggaagcggta gacatcttgc caaatgaaaa
    42241 agtagccatc gtgaataata ataatggtgc acgttttgaa acatacgtaa tagctggtga
    42301 aagaggtagt ggtaaaattt gtttgaacgg tgcagcatca agacttgttg aagtaggcga
    42361 tgtagtcata atcatgactt atgcacagtt aaatgaagaa gaaattaaaa accatgctcc
    42421 taaagtagca gtaatgaatg aagacaatgt cattattgaa atgattcatg aaaaagaaaa
    42481 tacgatagtg ttataaaata gtataagtta gaaacctcta gtagataaca atgtagttat
    42541 ccattagggg tttttatttt tatgccaatt gggttagcgt aatagaagta aaggtattat
    42601 cgttgcaatt ttatcagtgt taaatgatgg acatatttat aaagaaatag ttttgcgaat
    42661 tgattatcta aaacagtatt cagaatttat ttggtagaaa atagaattct taacttaacg
    42721 agataagtta atgacatgtt gtttagtttc gtgaagtaaa aatattgaat tgatagcaat
    42781 tatataataa aattatatga aatagataaa aataatatag attaaaggag gaatgcctat
    42841 gacaaaaatt tttaaaatat catttttgat tttgttagta gtaattgttt ctagttatta
    42901 tggtgaaagt tttgtcttag ctgataataa tcctatcgtc aattcagaaa atggtagtga
    42961 taataatttt gaatcaggaa caattgaacg taatcaaaat gagctttatg aagtaggtga
    43021 ttatagtacg cccttaactg agcgagtttt cggtaaagat caaagaacgg ttgttaataa
    43081 tattttacaa agaccttata agcagactgt attattaaat atgacgtttt caaataaccg
    43141 tgtatataaa ggcaccggta ctatgattgg taaggacatt gtattgacag cggctcataa
    43201 tgtctattct aaagacgata agggttgggc taaaaagatt gatgtctatg ctggagtaaa
    43261 tgggcaaaca tatacaatag gaaaggcctt ttcgcataag ttttttgtat ctaaaacttg
    43321 gattaataat gctcctacaa aagaagatat agcaattatt aagttaaata gtaatttagg
    43381 aaataaaaca ggttacttaa ctttgaacac acacattagc aaaggtgaaa atattgaaat
    43441 ttctggattt ccaggagaca agtcagacaa cagacaatat aaaggtaaag ggaaattaga
    43501 aagttttgat gagaatgaaa tgtattatac ggtagacaca ttttcaggac aaagtggtag
    43561 tgcgataaga gattcaaaaa acaatatcat cggagtacat gcatacggca gatataatca
    43621 taattcaggc gtgagaataa atgatttaaa attagattac ataaattatt ggataggtaa
    43681 gtatagaagt catccatata ataagaaagt gaaagtaatt aaaagtaagt atatatattg
    43741 gaaaaacatt gaaattacaa aaaagggtga taataaatta attaaaaaag ataaagcgta
    43801 cacagctaaa ctctattaca atattccaaa tgggtataaa tattactctt tatacgacga
    43861 aaaaaataga tggatgggtt actttaatag caatgatatt aaggtagtaa aataggaaag
    43921 gatgaataag atgaaaaaag ttataagttt atttgttgca attttatcag tgttgatttt
    43981 tacggataat gcgaacgccg aaaataacaa acctgaaggt gtgaatgaaa acagcaattt
    44041 aataccagtt agacaaccgg atgcaaatta tccagggcca gttagtgaca tagcacgtgt
    44101 gaaaaaactt gataatttaa tagatggcac gaaagatcca gatgttatca agcagttgaa
    44161 agatgataat gaggtgccga ataatgcggt aaaggcaaaa gattctaaaa tagtatccga
    44221 ctgcagacat ttactaaaac atccagataa tttaatagat ggcacgaaag atccaaatgt
    44281 tattaatcag ttgaaaaacg caaatggaac atcgaataat agtgctgtaa atccaagtat
    44341 taaagcaaat gatattcaca caaaaagtaa taaacaaatg gctaaacaac aaagtattca
    44401 tttggatagc aagagcaagt cagtacataa gcaacaattg aaagaattgc caaaaacagg
    44461 agtaaacaac gaaagtaata cagcaataat ggctttattt attggtttaa tattgcttgt
    44521 agtaagttta gtgacaagat ttataaaatt aaatagccat caataataaa aagggccaca
    44581 ccttggttta agattccaag cgtgtggcct tctcttctat cactatgtca cttttaatca
    44641 aaatcgaccg taattcctgc atgtcaatta acgataggaa tgattaattg tgaatcatat
    44701 ttaccaccag tataaatcat gtgcatgccg ttatttatgg tttcttcatg ttcataacgt
    44761 gttttcatgc caggggtact attaccaatt acaatttcac taccttttac aacaacttcc
    44821 aatgtttcgc cttgtttaaa tagcgtgcct gaaggtaaca attcgatttc aacaggtaca
    44881 atctcatctt gtgacaactt taattctgtt tcatgtttat gccaaggttg cgcgattgtg
    44941 gatttttctt gatctaattc acgatgtgat acgcgtaacc aaccagtagc tacttgacca
    45001 ttttcaatat gattaaaatc agggaagtta acttcattac cacgacgatc taacttttta
    45061 atacctgcaa ataaatccat atcgtctgag tctgtagtgc ttacccatag ttttaagttc
    45121 atgtttccaa ctaactcagt atctttgtca aacgtatatt taaaacttac atcttgtcgt
    45181 ttatcttcag agtcatattg tgcgacatac gcgctactaa tctttgcatg attcaatgtg
    45241 tgattttcag catttaaata caatggtgta tattctgtgt taggtaaagg gaacgctgac
    45301 gctgatttga attcgccttt ataaaattga tctctaactt catatatgac atgaggcgta
    45361 tctttccaat cgttattttc ttctttaagg taaaaatcaa agaatgattt ttggcgttcg
    45421 agattttctc tagcgtagta actttcccac tctttacgtc catgcacata tagccatttt
    45481 tcttctgatg cagcttgttt aaatccttca aaagagccac ggttgtgcaa accttgtgta
    45541 gaccaactag cacatgttag tagaggtgtt ttaatttgtg ataatggcac ttgacgctgt
    45601 ttccaaaaat catcgaacaa agggtgttct tgttgtgctt gaatcatgtc ttcgatattt
    45661 ggattatctg tccatctcgc aaaaatacct tgtatccaga aacgataaaa gccagtatca
    45721 ggaatacccc cgtgaaaggc tacttctcta tacatatcat ttaatccttc ccaaggaatc
    45781 attgctttta aatgtggtgg atttaatgat gcgacccacc attgagtcac cgcaagataa
    45841 gaaacaccat ttgttccgat atttccatta ctccatggct gttttgctgc ccattcaatc
    45901 acttcgtaat aatcttccgc ttctcttttt gaccatggag ataagacgcc tttggatttg
    45961 tcactaccgc gtaatgcaac tttaactaca acataatcgt ttggtaccca aaatcctggg
    46021 tctggtgatt cttcaggtgt aaaactagat gtcggaatgg cgcctaatgt tggccaaagg
    46081 gcacccatat tggtgatttt aggcttatta tctttaccgt aagtatctgc agacataact
    46141 acagggaatt tgccatcttt atttggtctg aaaatattaa tatataattt ttcgccatcg
    46201 cgcatttcca cagtgacatc tttttccata atcatttctt gatttccata ttgaacactg
    46261 tcgacaacga tgtggttaat accggttttc acttcattga catgagttac agttaatttt
    46321 ggatttccta gtaaatgttg gttcattgtt atcacctttt tctgtttgtt tgtatcacct
    46381 atattaaaca ggtaaacatt gtgtgccaat catcaatgtt ggagatttgt gggataatga
    46441 acataacgtt tataattgtt tataatcatt ggggaggact tgatataaat gactatagat
    46501 cgacgtatta gaaaatcaca agttgcaatg agaaatgcat ttattgaact tttacatcaa
    46561 caccaattag aagagattac tgtgcaacaa attgcagatt tagctgatgt taaccgtagt
    46621 acattttata cgcattatta tgataaatat gatttgcttg aaaaattaga ggaccagcag
    46681 ttggaggaaa taagagactt cattcatgat gagaagttaa atggagcagt taagttatcc
    46741 acggataaca tacatcaaat tatgactgtt ttaatagata tgatagaaaa agacatcgca
    46801 ttttatcaat tgatgtttcg tatgggtaaa gattcaaata tacacgaaaa actatatgac
    46861 ttaattatgt gtcatttaca acgttataaa aatgaaaatg atcaaattaa tggtatacca
    46921 ttttcttatt tcatgagtta tgtttcaggt gcgggattgt ctttgataag acattgggta
    46981 gaagatccaa accgtataga caaagttgac ttaataatgc attttaatac gattgtcaat
    47041 caagggccag caacgataat taaaaatata caataaaata aggcaagcca tgaatcgaga
    47101 gtggcttgcc ttgctaaata acataagctt attaaatgat atctttatca ataacattat
    47161 tgttggattg cagtatagtc ttgaccatgt aacatccaac gaacaccgta tttatcggta
    47221 aagacgccca ttttgccacc ccagaattgg tcagcaaacg gtaattctat ttcaattgaa
    47281 gaatgatctt taattttctc atagaatgct tcaactttat cagcatcttc cttattgtta
    47341 acatcataat caattaataa tgatatgcca ttattaattt tgtcagcgcg accaaaagaa
    47401 tcagaacata gcacttttac gccaagcact tcaaattcag catgcatagt tgcttcttgc
    47461 gcttcttcct tagtcatacc aaaatgtgac gcttgttctt cgccaacttc taaacgttta
    47521 acgtcagttg caccaaatac ttcttcgtaa tatgcaaggg cttcttttga attttcaaaa
    47581 gcgatataag ggaataatgc tgtcatgtaa aacacctcaa tgtagtattt ttattactaa
    47641 caccatgtta cattaaaaaa tggcaaaagt ataactttta cgatgaattg aagtcaatct
    47701 tttgtaaaat acacgataaa ttgtaagatg aaattgattt aaatgaagta aacatatata
    47761 tgacatacaa aaaatgaaaa tgacacagag acgtatgtgt tgtttagtgt tttaaaattc
    47821 aagtttaaaa aatgctttta gatacataag ggactttcga aatataaatg cattaaaatg
    47881 aatttctaac ttttttgact gacatttaat atgaatcata tataatagaa gttaatgatt
    47941 aaatgtggga ggttaaatca tgattaatgc tgaacctatt atcagtaaaa tgaaaaatca
    48001 aaaaattaat tatgacaagg tgttgaagaa attaatcggg cagtgggaaa gagaagcaat
    48061 cagacctaaa atcttattgc atagttgttg tgcaccttgt agtacatata cattagagtt
    48121 tttaacacaa tatgcagaca ttgcaattta tttcgcgaat tcaaatattc atccgaaaaa
    48181 tgaatattta cgacgtgcta aagtgcaaga acaatttgtg gaagatttta atcgcaagac
    48241 tggtgcgaat gtgaagtata ttgaagcacc ttatgaaccg cataagtttg tgaaaatggt
    48301 gaaggataaa gaattagctg atgaaaaaga aggcggctta cgttgtaccg cttgttttga
    48361 aatgcgtttg gatattgtag cgaaagcagc tgtagaacat ggctatgatt attttggcag
    48421 tgcaatcacg ttatcaccta aaaagaacgc acaattaatc aatgaacttg gtatggatgt
    48481 ccaaaaaata tacgatgtga actatttgcc aagtgatttt aagaaaagta aaggttatga
    48541 gcgttccata gaaatgtgta atgactataa tatctttagg cagtgttatt gtggatgtgt
    48601 ctttgcagcg atgcaacaag gtattgattt taaaacagtt aataaagaag cgaaagcatt
    48661 tttagaacaa tatccagatt aatcattgga aatgagataa aaggcaggct cgtatacatg
    48721 ccatatccca ttaaaaatta tcaaatagaa acccgagatt ttagtgaaat gaatcatact
    48781 aaaatctcgg gttatttata taatcgtaaa tattgtagct atactgaata actggatcct
    48841 gagacataaa acaatgtctc actctaatta aatcatttta tgaacaaatc ttataattgc
    48901 taaaatgaca atgacaagtg ttgaaataag tgaaaacact ttaaactttt tgtagtcgtt
    48961 tttcgtttca ttttctcctg ttttcatcat ttcacgtagc tcttgctcaa tttctaaatc
    49021 aagatctgtt ttacgataac cattcaaacc ttgacgttca tcttcttcag tttgattttg
    49081 ttgctgtgtg tctttgttgt cagaagtcgc tactgttttt ttattatctg tttctttagt
    49141 cataacaaac gcctccgtta taaaacgcta tatttaatga tatgtgatat ttaagccatt
    49201 attttgaaaa atggtgataa atatatcttc ttgagttata tcataatttt aataagacga
    49261 ttcagcaagt tttaaagtgt tatttgacta cgttggatta ggcatctagt cctataatat
    49321 cactgacatt gtcaaaatga tgatctttta agtaacgtgc gatgcctttg ttcattttct
    49381 tagttaaacc tgggccttca ataacaagtg atgaataaat ttgaataagt gacgcaccgt
    49441 gacgcatcat tttgattgca tcttcagtac tgaatacgcc gcctgtacct ataattaaaa
    49501 attcaccatt tgtttgctga taagcatact taatcaattt taaattacgt tcaaataatg
    49561 gacgaccact caaaccgcct tcttcgactt tattagcaga agttaaacca tctcgttgtc
    49621 gcgttgtgtt tgctaagatg ataccgtcaa atgtctcagt aatcgctggt aatagtgctt
    49681 ttaagccatc gaaatccata tcagacgtta gttttaagta aattggcact gttacatcgt
    49741 gctgtttttt aaatgttgtc aaagcttgac ataacattga aaattcatct ttatcatgga
    49801 aattttgaag gttttcagta tttggagaac tgatattgac tgtgaaaaat gaaacgtcgt
    49861 gtttaaacgt atcaatgact tttatataat cttgataacg cgcttcataa ggtgtcattt
    49921 tattcacacc aacattgata ccaacaggta cttgataagc atttttacgc aaatgactga
    49981 gtgctttgtt cataccaata ttattgaagc ccattcgatt tatcaaggcg tcatcttcta
    50041 ataatctaaa catgcgtggt tgagggttac ccggttgagg tttaggtgtg ataccaccta
    50101 attctaaagc accgaatcca aggtgttcca atgcttttgg tacttcgcaa gatttgtcga
    50161 aaccagctgc taagccaatt ggattgtcgt acgtattacc ttgtatcgtt tgtgataacg
    50221 ttggattctt ataagtaaat agtttatcga cgactgggaa taaaaccgga aacttttgta
    50281 acgtttttaa tgcatcgata gttagtccgt gtgctttttc gggttcgatt ttgaataaga
    50341 aaggtttaat taatttgtac atgagtatgc tcctatttca ttatatttga ggcttactat
    50401 cctcaactta atatatgtga aatatattct tttaatagac tagcatttcc ctacataatt
    50461 tcctagttaa aactaaaaag ttttgaaaat tgacgcaagt ttgaataacg tttttaagat
    50521 taaatcatcc taattaggca atattatagt ataaagtaag tagattggaa ggtgtttgta
    50581 tgaatgaaca atggttagag catttacctt taaaagatat taaagagatt tcaccagtga
    50641 gtggtggtga tgtaaacgaa gcatatcgag tcgaaacaga tacggataca tttttcttac
    50701 ttgtccaacg tggacgtaaa gaatcatttt atgctgcaga aattgcaggt ttaaatgaat
    50761 ttgaacgtgc aggtatcacg gcacctagag taattgcaag tggcgaagtt aacggtgatg
    50821 tgtatttagt gatgacgtat ttagaagaag gagcttcagg gagtcaacgt caattaggtc
    50881 aactcgtagc tcaattacac agtcagcaac aagaagaagg caaatttggc ttctcattac
    50941 cttatgaagg tggcgatatt tcttttgata atcattggca agatgattgg cgtaccattt
    51001 ttgtcgataa acgtttggat catttgaaag aagagttgct aaatagaggg ctatgggatg
    51061 ccaacgatat caaagtatat gacaaagtgc gaagtcaaat tgtggaggaa ttagaaaagc
    51121 atcaaagtaa accgtcttta ttacatggtg atttatgggg cggtaattat atgtttttaa
    51181 aagatggacg tcctgcatta tttgatccag caccattata tggtgacaga gaatttgata
    51241 tcggtattac aacggtattt ggtggtttta cgagcgaatt ttacgatgcg tataataaac
    51301 attatccgct cgcaaaagga gcatcctata gacttgaatt ttatcgttta tatttattga
    51361 tggtgcattt attgaaattt ggtgagatgt accgtgatag tgttgcgcat tctatggata
    51421 ggattttaca aggtacaaca agttagttaa gacgttagat tgagataaat agataatatg
    51481 cacagatatt ttatgaagag aaggccttca gttgcctcaa taaaaatatt tgtgcttttt
    51541 tattgctgga aaataaaatt ttaatcgcta ttgttaattt ctgtaatgca aaacaaggtt
    51601 gagttgcaat aaaagtgatt ttataacttt ttgttcaata aaattctagg aatgatacat
    51661 atttattgat acaataattt tgaatataat cacaaaacaa tatttaagta ttattgaatg
    51721 tttgaatatc atattgtcac tttattcgat atatgagaat gattttacct aataaatgag
    51781 aaaagcaacg cactatatta aaatgcgttg ctttttctat tatcgaatac ctataactaa
    51841 actatctcta gctgtttcta caacttctgt acttatttta tctaaaccat ttatatccat
    51901 aatttaattt ctttttggag gccacacaaa atatgaaata caaataatta agtctataat
    51961 aataacaatt gtccaaatat gaataacacc atccatagct tctgtacgac ttttatcatt
    52021 aattaaataa acaattaaat gtaaaatccc agtacctata atgtaagaca gtaaatgttt
    52081 caaccaactt ttagcatagt ttttagagta agctaaaccg tcaagtttat aaggtttgga
    52141 accttgcttc atcacataat atctaaatct atcatctgcc caatttatca tgcttttgcc
    52201 aaagacaaga gaaattgaaa tataaactgc tgctatagca tgtggcattt cagctgttgc
    52261 accattcata aggtctacaa ccgttgttat aaggagtatt aaatctataa taggcgtaag
    52321 tgcaaggaag aataa
//
LOCUS       DAPDIM010000011        51033 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000011 DAPDIM010000000
VERSION     DAPDIM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 51033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51033
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.011"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            85..1359
                     /locus_tag="RFE25_000713"
     CDS             85..1359
                     /locus_tag="RFE25_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDU2815808.1"
                     /translation="MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALL
                     VLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSKKFGTVHEMIKSVSPTIVGVINM
                     QKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
                     QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSV
                     TSGIISASERTIDAETTGGNTKVSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAA
                     TQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIPEEEREQLHTDREDG
                     IYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKE
                     VKVKLKQQKEQPKRQSRSERQSPGQGDRDFFR"
     gene            complement(1453..2715)
                     /locus_tag="RFE25_000714"
     CDS             complement(1453..2715)
                     /locus_tag="RFE25_000714"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDU2815809.1"
                     /translation="MTNVLIEDLKWRGLIYQQTDEQGIEDLLNKEQVTLYCGADPTAD
                     SLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEG
                     ISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLRDYGKHVGVNYMLGKDSIQSRLE
                     HGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTDAYG
                     LTIPLVTKSDGKKFGKSESGAVWLDAEKTSPYEFYQFWINQSDEDVIKFLKYFTFLGK
                     EEIDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAIRISQALFSGDLKSLSAK
                     ELKDGFKDVPQVTLSNDTTNIVEVLIETGISPSKRQAREDVNNGAIYINGERQQDVNY
                     ALAPEDKIDGEFTIIRRGKKKYFMVNYQ"
     gene            3097..4002
                     /locus_tag="RFE25_000715"
     CDS             3097..4002
                     /locus_tag="RFE25_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDU2815810.1"
                     /translation="MTNQDNNHQLNHRIYHFEKIYKAIKHVIVFIFMIFIAIVAIAVI
                     AMSLYFHHLTKTSDSLSDDALIKKVRQIPGDELLDHNNKNLLYEYNHSQNSLIIGPKT
                     SSPNVIKALTSSEDTLFYKHDGILPKAILRAMIQDIFNTDQSSGGSTITQQLVKNQVL
                     TNEKTYSRKANELRLAIRLEHLLSKDEIIYTYLNIVPFGRDYNGANISGIASASYSLF
                     GIPPKDLSIAQSAYLIGLLQSPYGYTPYEKDGTLKSDKDLKYSIQRQHYVLKRMLIED
                     QITEKEYNDALKYDIKSHLLNRKKR"
     gene            complement(3982..4074)
                     /locus_tag="RFE25_000716"
     CDS             complement(3982..4074)
                     /locus_tag="RFE25_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815811.1"
                     /translation="MKIILLLFLIFGCIVVVTLKSEHQLTLFSI"
     gene            complement(4205..6880)
                     /gene="harA"
                     /locus_tag="RFE25_000717"
     CDS             complement(4205..6880)
                     /gene="harA"
                     /locus_tag="RFE25_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haptoglobin-binding heme uptake protein HarA"
                     /protein_id="HDU2815812.1"
                     /translation="MNKHHPKLRSFYSIRKSTLGVASVIVSTLFLITSQHQAQAAENT
                     NTSDKISENQNNNATTTQQPKDTNQTQPATQPVITAKNYPAADESLKDAIKDPALENK
                     EHDIGPREQVNFQLLDKNNETQYYHFFSIKDPADVYYTKKKAEVELDINTASTWKKFE
                     VYENNQKLPVRLVSYSPVPEDHAYIRFPVSDGTQELKIVSSTQIDDGEETNYDYTKLV
                     FAKPIYNDPSLVKSDTNDAVVTNDQSSSDASNQTNTNTSNQNTSTTNNANNQPQATTN
                     MSQPAQPKSSANADQASSQPAHETNSNGNTNDKTNESSNQSDVNQQYPPADESLQDAI
                     KNPAIIDKEHTADNWRPIDFQMKNDKGERQFYHYASTVEPATVIFTKTGPVIELGLKT
                     ASTWKKFEVYEGDKKLPVELVSYDSDKDYAYIRFPVSNGTRDVKIVSSIEYGENIHED
                     YDYTLMVFAQPITNNPDDYVDEETYNLQKLLAPYHKAKTLERQVYELEKLQEKLPEKY
                     KAEYKKKLDQTRVELADQVKSAVTEFENVTPTNDQLTDLQEAHFVVFESEENSESVMD
                     GFVEHPFYTATLNGQKYVVMKTKDDSYWKDLIVEGKRVTTVSKDPKNNSRTLIFPYIP
                     DKAVYNAIVKVVVANIGYEGQYHVRIINQDINTKDDDTSQNNTSEPLNVQTGQEGKVA
                     DTDVAENSSTATNPKDASDKADVIEPESDVVKDADNNIDKDVQHDVDHLSDMSDNNHF
                     DKYDLKEMDTQIAKDTDRNVDNSVGMSSNVDTDKDSNKNKDKVIQLAHIADKNNHTGK
                     AAKLDVVKQNYNNTDKVTDKKTTEHLPSDIHKTVDKTVKTKEKAGTPSKENKLSQSKM
                     LPKTGETTSSQSWWGLYALLGMLALFIPKFRKESK"
     gene            6879..6968
                     /locus_tag="RFE25_000718"
     CDS             6879..6968
                     /locus_tag="RFE25_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815813.1"
                     /translation="MLLTTPIRLYLIDNNYQYQLLVLIVAHPN"
     gene            complement(7213..8880)
                     /locus_tag="RFE25_000719"
     CDS             complement(7213..8880)
                     /locus_tag="RFE25_000719"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDU2815814.1"
                     /translation="MTHLSDLDIANQSTLQPIKDIAASVGISEDALEPYGHYKAKIDI
                     NKITPRENKGKVVLVTAMSPTPAGEGKSTVTVGLADAFHELNKNVMVALREPALGPTF
                     GIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALSAFIDNHIHQGNELGIDQRR
                     IEWKRVLDMNDRALRHVNVGLGGPTNGVPREDDFNITVASEIMAILCLSRSIKDLKDK
                     ISRITIGYTRDRKPVTVADLKVQGALAMILKDAIKPNLVQSIEGTPALVHGGPFANIA
                     HGCNSILATETARDLADIVVTEAGFGSDLGAEKFMDIKAREAGFDLAAVVVVATIRAL
                     KMHGGVAKDNLKEENVEAVKAGIVNLERHVNNIKKFGVEPVVAINAFIHDTDAEVEYV
                     KSWAKENNVRIALTEVWEKGGKGGVDLANEVLEVIDQPNSFKPLYELELPLEQKIEKI
                     VTEIYGGSKVTFSSKAQKQLKQFKENGWDNYPVCMAKTQYSFSDDQTLLGAPSGFEIT
                     IRELEAKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTDDGHAIGLF"
     gene            complement(9320..11026)
                     /gene="acsA"
                     /locus_tag="RFE25_000720"
     CDS             complement(9320..11026)
                     /gene="acsA"
                     /locus_tag="RFE25_000720"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HDU2815815.1"
                     /translation="MKVEVYKGAQGKHNLKDYEETYNTFDWKDVEQAFSWSETGKMNM
                     AYECIDRHVDQGLGDKIALNYKDEYRKESYTYKDMQRLSNKAANVLSEHAEVDKGDRV
                     FIFMSRTPELYFALLGVLKIGAIVGPLFEAFMEKAVADRLENSEAKVLITNKALLPRV
                     PVDKLPNLKKIVVVDEDVEDNYIDFISLMETASDEFDIEWLKSDDGLILHYTSGSTGQ
                     PKGVLHVQQAMLVHYISGKYVLDLQEDDVYWCTADPGWVTGTSYGIFAPWLNGATNCI
                     AGGRFSPEQWYSMIEDFKVTIWYTAPTALRMLMSAGDDIVEKYDLSSLRSILSVGEPL
                     NPEVIKWAKKVYGLTVLDTWWMTETGGHMIVNYPTMDVKLGSMGKPLPGIQAAIIDDA
                     GNELPPNRMGNLAIKKGWPSMMYRIWKNPEKYKSYFIGDWYVSGDSAYKDEDGYFWFQ
                     GRVDDVIMTAGERVGPFEVESKLVEHEAVAEAGIIGKPDPVRGEIIKAFVALRKGYEP
                     TDELKEEIRLFVKEGLSAHAAPREIEFKDKLPKTRSGKIMRRVLKAWELNLDAGDLST
                     ME"
     gene            11195..11827
                     /locus_tag="RFE25_000721"
     CDS             11195..11827
                     /locus_tag="RFE25_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDU2815816.1"
                     /translation="MNHLKTYQSEDYYIHDKQFVIEGPLTYEDLKALTLDAHLTAFRD
                     AEDQYEALLEITTLPEGRIYVARQDELIVGYVTFHYPDEIERWSTGNLPYLIELGAIE
                     VSINFKQLHLAEKLIQLSLSTPEFEDYIVITTEYYWHWDLKNSKLDVFDYKKLMQRLM
                     ATGGLEIFATDDPEITSHPANCLMARIGKNITLEQQQAFDDIRYMNRFFF"
     gene            11852..13021
                     /locus_tag="RFE25_000722"
     CDS             11852..13021
                     /locus_tag="RFE25_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoin utilization protein AcuC"
                     /protein_id="HDU2815817.1"
                     /translation="MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANL
                     LSPVQIVQPRIATGDELMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHM
                     HRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
                     KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGY
                     GHTVNVPLEPYTEDASFLECFKLTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTL
                     HSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLP
                     LEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ"
     gene            complement(13119..14108)
                     /gene="ccpA"
                     /locus_tag="RFE25_000723"
     CDS             complement(13119..14108)
                     /gene="ccpA"
                     /locus_tag="RFE25_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HDU2815818.1"
                     /translation="MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRL
                     NYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLARGLEDIATMYKYHSIISNSDNDP
                     EKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
                     FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSG
                     AESYKEGVKAFAKMKGNLPDAILCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRL
                     VEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPHRIEYRGTTK"
     gene            complement(14181..14294)
                     /locus_tag="RFE25_000724"
     CDS             complement(14181..14294)
                     /locus_tag="RFE25_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815819.1"
                     /translation="MKKVYIKLKYIVRYHLAFVFISSFSLNFSKQKYVTVN"
     gene            complement(14648..15739)
                     /locus_tag="RFE25_000725"
     CDS             complement(14648..15739)
                     /locus_tag="RFE25_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="HDU2815820.1"
                     /translation="MSNKLESYRSEIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRI
                     YDPQREKEMLNDLIDSNKGPFNDNTIKQLFKAIFKASTDLQKSENEKHLYVSRKLKPE
                     DTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSP
                     YDFQGLGVEGLKILKQIKDKYDLNVVSEIVNPNDFEVADEYLDVFQIGARNMQNFELL
                     KEAGRTKKPILLKRGLSATIEEFVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDI
                     SAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVMAEVHPDPSVALSDA
                     GQQMDLDEFQAFYDELKPLADLYNAKKLK"
     gene            complement(16194..16277)
                     /locus_tag="RFE25_000726"
     CDS             complement(16194..16277)
                     /locus_tag="RFE25_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815821.1"
                     /translation="MLFETSLDNNSYIAHFKLKMEKYSIIK"
     gene            complement(16433..17791)
                     /locus_tag="RFE25_000727"
     CDS             complement(16433..17791)
                     /locus_tag="RFE25_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815822.1"
                     /translation="MTQQQNDKRTLKNKHTYQNEPLPNRKDFVVSFITGALVGSALGL
                     YFKNKVYQKADDLKVKEQELSQKFEERKTQLEETVAYTKERVEGFLNKSKNEQAALKA
                     QQAAIKEEASANNLSDTSQEAQEIQEAKREAQAEADKSVAVSNEESKASALKVQQAAI
                     KEEASANNLSDTSQEAQEIQEAKKEAQAETDKSAAVSNEEPKAVALKAQQAAIKEEAS
                     ANNLSDTSQEAQEVQEAKKEAQAEKDSDTSTKDASAAKVEVSKPESQAERLANAAKQK
                     QAKLTPGSKESQLTEALFAEKPVAKNDLKEIPQLVTKKNDVSETETVNIDNKDTVKQK
                     EAKFENGVITRKADEKTTNNTAVDKKSGKQSKKTTPSNKRNASKASTNKTSGQKKQHN
                     KKSSQGAKKQSSSSKLTQKNNQTSNKNSKTTNAKSSNASKTPNAKVEKANSKIEKRTF
                     ND"
     gene            complement(17865..18356)
                     /locus_tag="RFE25_000728"
     CDS             complement(17865..18356)
                     /locus_tag="RFE25_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDU2815823.1"
                     /translation="MDWILPIAGIIAAIAFLILCIGIVAVLNSVKKNLDYVAKTLDGV
                     EGQVQGITRETTDLLHKVNRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNSSVDRVTN
                     SITHNISQNEDKISQVVQWSNVAMEIADKWQNRHYRRGSANYKANNVATDANHSYTSR
                     VDK"
     gene            complement(18430..19743)
                     /locus_tag="RFE25_000729"
     CDS             complement(18430..19743)
                     /locus_tag="RFE25_000729"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDU2815824.1"
                     /translation="MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALR
                     NKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYT
                     SVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLS
                     YKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPI
                     YYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISY
                     LEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHK
                     EVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEG
                     ASLINEDSINVLEQFDNAVVLFMGAGDIQKLQNAYLDKLGMKNAF"
     gene            complement(19767..23591)
                     /locus_tag="RFE25_000730"
     CDS             complement(19767..23591)
                     /locus_tag="RFE25_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDU2815825.1"
                     /translation="MSWFDKLFGEDNDSNDDLIHRKKKRRQESQNIDNDHDSLLPQNN
                     DIYSRPRGKFRFPMSVAYENENVEQSADTISDEKEQYHRDYRKQSHDSRSQKRHRRRR
                     NQTTEEQNYSEQRGNSKISQQSIKYKDHSHYHTNKPGTYVSAINGIEKETHKSKTHNM
                     YSNNTNHRAKDSTPDYHKESFKTSEVPSAIFGTMKPKKLENGRIPVSKPSEKVESDKQ
                     KYDKYVAKTQTSQNKQLEQEKQNDSVVKQGTASKSSDENVSSTTKSMPNYSKVDNTIK
                     IENIYASQIVEEIRRERERKVLQKRRFKKALQQKREEHKNEEQDAIQRAIDEMYAKQA
                     ERYVGDSSLNDDSDLTDNSTDASQLHTNGIENETVSNDENKQASIQNEDTNDTHVDES
                     PYNYEEVSLNQVSTTKQLSDDEVTVSNVTSQHQSALQHNVEVNDKDELKNQSRLIADS
                     EEDGATNKEEYSGSQIDDAEFYELNDTEVDEDTTSNIEDNTNRNASEMHVDAPKTQEH
                     AVTESQVNNIDKTVDNEIELAPRHKKDDQTNLNVNSLKTNDVNDGHVVEDSSMNEIEK
                     HNAEITENVQNEAAESEQNVEEKTIENVNPKKQTEKVSTLSKRPFNVVMTPSDKKRMM
                     DRKKHSKVNVPELKPVQSKQAVSESKPASQAAPSSRSDSQESNTNAYKTNNMTSNNVE
                     NNQLIGHAETENDYQNAQQYSEQKPSADSTQTEIFEESQDDNQLENEQVDQSTSSSVS
                     EVSDITEESEETTHPNNTSGQQDNDDQQKGLQPSFSNQNEDTANENRPRTNQQDVATN
                     QAVQTSKPMIRKGPNIKLPSVSLLEEPQVIESDEDWITDKKKELNDALFYFNVPAEVQ
                     DVTEGPSVTRFELSVEKGVKVSRITALQDDIKMALAAKDIRIEAPIPGTSRVGIEVPN
                     QNPTTVNLRSIIESPSFKNAESKLTVAMGYRINNEPLLMDIAKTPHALIAGATGSGKS
                     VCINSILMSLLYKNHPEELRLLLIDPKMVELAPYNGLPHLVAPVITDVKAATQSLKWA
                     VEEMERRYKLFAHYHVRNITAFNKKAPYDERMPKIVIVIDELADLMMMAPQEVEQSIA
                     RIAQKARACGIHMLVATQRPSVNVITGLIKANIPTRIAFMVSSSVDSRTILDSGGAER
                     LLGYGDMLYLGSGMNKPIRVQGTFVSDDEIDDVVDFIKQQREPDYLFEEKELLKKTQT
                     QSQDELFDDVCAFMVNEGHISTSLIQRHFQIGYNRAARIIDQLEQLGYVSSANGSKPR
                     DVYVTEADLNKE"
     gene            complement(23612..24208)
                     /locus_tag="RFE25_000731"
     CDS             complement(23612..24208)
                     /locus_tag="RFE25_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HDU2815826.1"
                     /translation="MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVG
                     YNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKD
                     KHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGV
                     ASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE"
     gene            complement(24237..25094)
                     /locus_tag="RFE25_000732"
     CDS             complement(24237..25094)
                     /locus_tag="RFE25_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1444 domain-containing protein"
                     /protein_id="HDU2815827.1"
                     /translation="MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIK
                     LNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQ
                     GVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSY
                     TTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRN
                     KTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEA
                     NRRKFNKDK"
     gene            complement(25194..25505)
                     /locus_tag="RFE25_000733"
     CDS             complement(25194..25505)
                     /locus_tag="RFE25_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDU2815828.1"
                     /translation="MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARY
                     PMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQY
                     V"
     gene            complement(25570..26646)
                     /locus_tag="RFE25_000734"
     CDS             complement(25570..26646)
                     /locus_tag="RFE25_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDU2815829.1"
                     /translation="MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMATYVDEFI
                     ENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQG
                     QRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGD
                     TIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGL
                     RGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPVFRDY
                     LLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYF
                     AARSLLSEAICNLDNNQIETLQYK"
     gene            26733..27044
                     /locus_tag="RFE25_000735"
     CDS             26733..27044
                     /locus_tag="RFE25_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDU2815830.1"
                     /translation="MTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKS
                     YFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVE
                     R"
     gene            complement(27169..28011)
                     /locus_tag="RFE25_000736"
     CDS             complement(27169..28011)
                     /locus_tag="RFE25_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDU2815831.1"
                     /translation="MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQI
                     NLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDID
                     YVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDY
                     SNKLILFEKHFEPVPGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLW
                     VTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDDGENIDAYILRETL
                     VDNN"
     gene            complement(28482..29126)
                     /gene="trmB"
                     /locus_tag="RFE25_000737"
     CDS             complement(28482..29126)
                     /gene="trmB"
                     /locus_tag="RFE25_000737"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDU2815832.1"
                     /translation="MRVRYKPWAEDYLKDHPELVDMEGQHAGKMTEWFDKTQPIHIEI
                     GSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEY
                     FKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAY
                     SLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK"
     gene            complement(29141..29932)
                     /locus_tag="RFE25_000738"
     CDS             complement(29141..29932)
                     /locus_tag="RFE25_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001602611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HDU2815833.1"
                     /translation="MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAAL
                     SAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSM
                     LKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDV
                     NHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNL
                     NKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI"
     gene            complement(30482..31330)
                     /gene="dat"
                     /locus_tag="RFE25_000739"
     CDS             complement(30482..31330)
                     /gene="dat"
                     /locus_tag="RFE25_000739"
                     /EC_number="2.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino-acid transaminase"
                     /protein_id="HDU2815834.1"
                     /translation="MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFT
                     VTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHS
                     FPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYA
                     VKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYN
                     IPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPINDGKVGPITRQLQEGFEKY
                     IESHSI"
     gene            complement(31334..32743)
                     /gene="sapep"
                     /locus_tag="RFE25_000740"
     CDS             complement(31334..32743)
                     /gene="sapep"
                     /locus_tag="RFE25_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mn(2+)-dependent dipeptidase Sapep"
                     /protein_id="HDU2815835.1"
                     /translation="MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRK
                     ALDYMYEIAHRDGFTTRDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPV
                     VTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYF
                     KTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMV
                     PDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIG
                     VNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGV
                     ITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPF
                     VQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQ
                     LFNATSIYLEAIYSLCVEE"
     gene            complement(33187..33609)
                     /locus_tag="RFE25_000741"
     CDS             complement(33187..33609)
                     /locus_tag="RFE25_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDU2815836.1"
                     /translation="MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQS
                     YKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFEEEKSKFTEYDNKTDE
                     SIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE"
     gene            complement(33626..34321)
                     /locus_tag="RFE25_000742"
     CDS             complement(33626..34321)
                     /locus_tag="RFE25_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDU2815837.1"
                     /translation="MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPE
                     NDKITVRGELIEYIENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLD
                     KDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVTLTDGKVK
                     PAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYR
                     LLTENDFDKLNYK"
     gene            complement(34318..35979)
                     /locus_tag="RFE25_000743"
     CDS             complement(34318..35979)
                     /locus_tag="RFE25_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDU2815838.1"
                     /translation="MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAP
                     FTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGF
                     LVLYFLAPYISELTLARNIHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYK
                     SMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLW
                     YYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHN
                     GALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEM
                     HHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAP
                     VAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIA
                     LLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLG
                     YLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR"
     gene            36386..37654
                     /locus_tag="RFE25_000744"
     CDS             36386..37654
                     /locus_tag="RFE25_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDU2815839.1"
                     /translation="MYQTIIIGGGPSGLMAAVAASEQSSSVLLIEKKKGLGRKLKISG
                     GGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMF
                     PVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQNNSYESHSLVIA
                     TGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVEL
                     SVLKKNGKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPEL
                     NHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLN
                     DLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHG
                     YTGGYNITSALVTGHVAGLYAGHYSHTSME"
     gene            complement(37771..44331)
                     /gene="sasC"
                     /locus_tag="RFE25_000745"
     CDS             complement(37771..44331)
                     /gene="sasC"
                     /locus_tag="RFE25_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored repetitive surface protein SasC"
                     /protein_id="HDU2815840.1"
                     /translation="MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNV
                     QSDTNQATPVNSQDTNVANNRGLANSAQNTPNQSATTNQSTNQALVNHNNGSIANQAT
                     PTSVQSSTPSAQNNNHTDGNTTATETVSNANNKDVVSNNTTLNVPNKTNENGSGGHLT
                     LKEIQEDVRHSSDKPELVAIAEQASNRPKKRSRRAAPADPNATPADPAAAAAGNGGAP
                     VAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPSVTVVDNLPGFTLIN
                     GGKVGVFSHAMVRTSMFDSGDAKNYQAQGNVIALGRIKGNDTNDHGDFNGIEKSLTVN
                     PNSELIFEFNTMTTKNYQGVTNLIIKNADNDTVIAEKSVAYGPIWRLFKVPENVSHLK
                     IQFVPKNDAITDARGIYQLRDGYKYYDFVDSIGLHSGSHVYVERRTMEPTATNNKEFT
                     VTTSLKNNGNFGASFNTDDFVYKVQLPEGVEYVNNSLTKDFPSSNSGVDMNDFNVTYD
                     AANRVITIKSTGGGSGNSPARLMPDKILDLKYKLRVNNVPTPRTVTFNDTLTYKTYTQ
                     DFINSPAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNDLKRRAQT
                     ILDENRNNVPLNKRVSQANIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDEL
                     TDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKK
                     AIRDKATKQREIINATPDATEDEIQDALNQLATDETDAIDNVTNATTNADVEIAKNNG
                     INTIGAVVPQVTHKQAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHAL
                     EQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDAT
                     QEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNA
                     IDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGT
                     QNIVVIQPATQVKTDARNAVNDKAREAITNINATPGATREEKQEAINRVNTLKNRALT
                     DIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATT
                     EEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQI
                     NQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAEN
                     NIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQ
                     INQNQTNDQVDTTTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDN
                     EKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKIN
                     QKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDS
                     IALVAPEHIVRAAARDAVKQQYEAKKQEIEQAEHATDEEKQVALNQLANNEKLALQNI
                     NQAVTNNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKATAENQVESIKDTPHATVDE
                     LDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEE
                     NNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNI
                     KVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQIN
                     HADKTAQVNQDSIDAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQ
                     NIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTL
                     FNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIH
                     DLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKT
                     ARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKV
                     KVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKV
                     CTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES"
     gene            complement(44657..44968)
                     /locus_tag="RFE25_000746"
     CDS             complement(44657..44968)
                     /locus_tag="RFE25_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDU2815841.1"
                     /translation="MKSITTDELKNKLFESKPVQIVDVRTDEETAMGYIPNAKLIPMD
                     TIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKS
                     I"
     gene            complement(44990..47407)
                     /locus_tag="RFE25_000747"
     CDS             complement(44990..47407)
                     /locus_tag="RFE25_000747"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDU2815842.1"
                     /translation="MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPS
                     GAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTK
                     KNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCP
                     ALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDM
                     QRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYK
                     EKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTG
                     AIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAI
                     TKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLL
                     PETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPK
                     NENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGIVPTKEPFQKLFN
                     QGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGS
                     RRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLM
                     VFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALL
                     VDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQK
                     LVNIVAK"
     gene            complement(47695..48876)
                     /locus_tag="RFE25_000748"
     CDS             complement(47695..48876)
                     /locus_tag="RFE25_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2815843.1"
                     /translation="MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAG
                     LVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLV
                     MLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYI
                     FLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICW
                     VAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPVLYLLKGNLKKQMF
                     VGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQG
                     FVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKID
                     A"
     gene            48986..49939
                     /locus_tag="RFE25_000749"
     CDS             48986..49939
                     /locus_tag="RFE25_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500380.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDU2815844.1"
                     /translation="MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRD
                     GTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTH
                     APVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIH
                     QSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDV
                     QGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGP
                     IDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ"
     gene            49936..50499
                     /locus_tag="RFE25_000750"
     CDS             49936..50499
                     /locus_tag="RFE25_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDU2815845.1"
                     /translation="MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPE
                     GHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYL
                     PKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQ
                     KHAQVLQYQFLNQRNHAPFICAIEKIS"
     gene            complement(50622..51023)
                     /locus_tag="RFE25_000751"
     CDS             complement(50622..51023)
                     /locus_tag="RFE25_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDU2815846.1"
                     /translation="MKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILL
                     TLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQ
                     QEKVELLNFISDAIASRATAMQNSLNAIIAV"
BASE COUNT        15468 a         9371 c         7410 g        18784 t
ORIGIN      
        1 aaagttgtat agtgtattac tagcaataat tataaaaaaa agacataatt aaagcatata
       61 taaatcatat aatggaggtt aagtatgtca gattttaatc atacagatca ttctacaaca
      121 aaccatagcc aaacacctag atacagaaga cctaaatttc catggtttaa aacagtcatc
      181 gttgcattga ttgctggaat tattggtgca cttctagtac ttggtatagg caaagtatta
      241 aatagtacaa ttttaaataa agatggttca actgttcaga caacaaataa taaaggtggc
      301 aatcaattag acggtcaaag caagaaattc ggtaccgttc atgaaatgat aaaatctgtc
      361 tcccctacaa ttgttggagt tattaacatg caaaaagcat caagtgtaga cgacttatta
      421 aaaggcaaat catctaaacc atctgaagct ggagtaggtt caggtgttat ctatcaaata
      481 aacaacaatt cagcttatat cgttacaaac aatcatgtta ttgatggcgc aaatgaaatt
      541 agagtccaat tacataataa aaaacaagtt aaagcgaaat tagttggtaa agatgcagta
      601 actgatattg ctgtacttaa aattgaaaat acaaaaggta ttaaagcgat tcaatttgcc
      661 aactcttcaa aagtacaaac tggcgatagc gtattcgcaa tgggtaaccc attaggatta
      721 caatttgcta actctgtaac atctggtatc atttcagcaa gcgaacgtac gattgacgct
      781 gagacaactg gtggcaatac aaaagttagc gttcttcaaa cagatgctgc tattaaccca
      841 ggtaactcag gtggcgcatt agtagatatt aatggtaatt tagttggtat taactcaatg
      901 aaaattgctg cgacacaagt tgaaggtatc gggtttgcta ttccaagtaa tgaagttaaa
      961 gtaacaattg aacaacttgt aaaacatggt aaaattgacc gcccttcgat tggtattggt
     1021 ttaattaatt tgaaagatat tcctgaagaa gagcgcgagc aacttcatac tgatagagaa
     1081 gacggtattt atgtcgccaa agctgatagt gatattgatc ttaaaaaagg tgatattatt
     1141 acagaaattg atggcaagaa aattaaagat gatgttgatt taagaagcta tttatatgaa
     1201 aataaaaaac ctggtgaatc agtcactgtt accgttatcc gtgatggtaa aacaaaagaa
     1261 gttaaagtga aattaaaaca acaaaaagaa caaccaaaac gtcaaagccg atcagaacgt
     1321 caatcacctg gccaaggcga tagagatttc tttagataat ttacagacag aaaagtacat
     1381 taagagccta ctcattacat tcttaggaat gaatatgagt aggctctaat ttatttagct
     1441 atgcaattat atttattgat agttaaccat gaagtatttt ttcttaccgc gacgaataat
     1501 cgtaaattcg ccatcaattt tatcttctgg tgctaaagca taattaacat cttgttgtct
     1561 ctcaccatta atataaatcg caccattgtt aacatcttca cgtgcttgtc gtttagaagg
     1621 agaaatgcct gtttcaataa ggacttcaac gatatttgtt gtgtcatttg ataatgtcac
     1681 ttgaggcaca tctttaaatc catcttttaa ttctttcgct gataatgatt ttaaatcacc
     1741 actaaataat gcttgtgaaa tacggattgc atcatttaat gcatcttcac catgaataaa
     1801 tttagttact tcttcagcta atgttttttg agcttcacgt aaatgcggtg cttcattttt
     1861 agattgttct aagcgatcaa tttcttcttt tcctaagaaa gtaaagtatt ttaagaattt
     1921 aattacatct tcgtctgatt gattaatcca gaattgataa aattcataag gacttgtttt
     1981 ttcagcatct aaccaaacag cacctgactc agacttacca aatttcttac catctgattt
     2041 agttacaagc ggaatagtta aaccgtatgc gtctgtttga ccatacatac gacgcattaa
     2101 ttcaatacca cttgtgatat taccccattg atctgatcca cctacttgaa tcttacaatt
     2161 caattctcta ttcaaatgac cgaaatcaat agcttgtaaa atcgtgtatg tgaattctgt
     2221 atatgaaata ccatgttcta aacgactttg gattgaatct ttacctaaca tgtaattaac
     2281 gccgacgtgt ttaccatagt cacgtaaaaa gctaattaat gagatttgtc ctaaccagtc
     2341 tctattatta acaagcactg caccatggtc tgttccaaat tcaaaaatat tgtgcatttg
     2401 cttactaata ccttcgatat ttttatctac ttgttcttct gtttgtagca cacgttcttc
     2461 tgatttacct gatggatcac caatcatacc tgtaccaccg ccaattaaaa cgataggacg
     2521 atgtccatgt tcttgaaaac gtcttaatgt taagaatggt agtaagtgac caatatgtaa
     2581 actatctgcc gttggatcgg caccgcagta taacgtcact tgttctttat ttaataaatc
     2641 ttcaatacct tgttcatcag tttgttgata aataagacct ctccatttta aatcttcaat
     2701 taatacattc gtcattatta tttcctccta tttataatta tttattgaat acttgttaaa
     2761 atactttaaa gttttttgaa cgtaaaaaaa acccttacaa caaatatgta agggcgcgat
     2821 tgcacgttac caccaaactt aaacataatc ataagataat gttcactcta ttaatgatac
     2881 gttcattaat aaacgtagga catgttagtt ataaaggtgt attcatatta ttaaaaacac
     2941 tagttcacag cgaccactag ctctctgatg atttcaaata atattacttg tccttttatc
     3001 ctattcttta tgcattttcc ctaattataa ttaacgttaa aataaaagtc aaattgctta
     3061 aatatggtat actatacgta atttaggagg ttaaagatga cgaatcaaga caacaatcat
     3121 caattgaatc atcgtatata tcattttgaa aagatatata aagctatcaa acatgtcatt
     3181 gtttttatat ttatgatttt cattgccatc gttgctatcg ctgtgattgc gatgtcttta
     3241 tattttcatc atttaactaa aacgtccgac tcattatcag atgatgcttt aataaaaaaa
     3301 gttcgacaaa tacctggcga tgaattatta gatcataata acaaaaattt attatatgag
     3361 tataaccatt ctcaaaactc actcattata ggccctaaaa catcaagtcc aaatgtcatt
     3421 aaagcattaa catcatctga agacacttta ttttataaac atgatggcat cttaccaaag
     3481 gcgattttaa gagcaatgat acaagatatt tttaatactg atcaaagttc aggtggtagc
     3541 acaattacac aacaacttgt taaaaatcaa gttcttacca acgaaaaaac atatagtaga
     3601 aaagcaaatg aacttcgcct agcaattaga ttagaacacc tactctcaaa agatgaaatt
     3661 atatatacat atttaaatat agttcccttc ggtagagatt ataatggcgc taatatttcc
     3721 ggaattgcat ccgcttcata tagtttgttt ggtattccac caaaagattt atcaattgca
     3781 caatctgcat accttatcgg tttgttgcaa agcccttatg gctatacacc ctacgaaaaa
     3841 gatggaacgt taaaatcgga taaagatttg aaatatagta ttcaaagaca acattatgta
     3901 ttaaagcgta tgttaatcga agatcaaatc actgaaaaag aatacaacga cgcattaaaa
     3961 tatgatatta aatcacattt gttaaatcga aaaaagcgtt aattgatgct cactttttaa
     4021 agtaaccaca acaatgcatc caaatattaa aaacagcagt aagattattt tcaattagaa
     4081 aatttctcac tgctgttctt tttatttact ctaaaggaaa gccattaaac caatcaatag
     4141 tttataaatt aattgctttc acattgttta caaagttaac catacatatg ctatatttag
     4201 ttaattattt agattctttt ctgaatttag gaatgaataa agctaacata cctaataacg
     4261 catataagcc ccaccatgat tggcttgaag ttgtttctcc agtttttggt agcattttag
     4321 attgactaag tttgttttct ttcgatggtg tgccggcttt ttcttttgtt ttcactgttt
     4381 tatctacagt tttatgaata tcactcggca gatgttcagt tgtttttttg tcagtaactt
     4441 tgtctgtatt attataattt tgtttcacta cgtcaagctt tgctgctttt ccagtatgat
     4501 tatttttatc ggcaatatga gcaagctgta tgactttgtc tttattttta ttagagtctt
     4561 tatcagtatc gacattcgat gacataccaa cgctattatc cacatttcta tcagtatctt
     4621 tggcaatttg agtatccatt tcttttaaat catacttatc gaagtgatta ttatccgaca
     4681 tatcggataa atgatcaaca tcatgttgca catctttatc aatattatta tcagcatctt
     4741 taaccacgtc agactctggt tctatcacat ctgctttatc agacgcatct ttaggatttg
     4801 ttgcagtgct gctattttca gctacatctg tatcagcaac cttaccttct tgtcctgttt
     4861 gtacatttag cggttcactc gtgttatttt gtgatgtatc atcatctttt gtattgatat
     4921 cctgatttat aattctgaca tgatattgac cttcataacc aatgtttgcc acaacgactt
     4981 taacaatcgc attgtaaact gctttgtcag gtatatatgg gaaaatcaac gttctagaat
     5041 tatttttagg atctttagaa acagtagtga cacgtttacc ttctacaatt aaatctttcc
     5101 agtaactgtc atcctttgtt ttcatcacta catatttttg accatttaaa gttgctgtat
     5161 agaatggatg ttcaacaaag ccgtccataa ctgactcact attttcttca ctttcaaaaa
     5221 caacaaaatg cgcttcttgt aaatctgtta attgatcatt tgtaggtgta acattttcaa
     5281 attccgtcac tgctgattta acctgatcag ctaactctac tctagtttga tctaatttct
     5341 ttttatattc cgccttatat ttttctggca atttctcttg taatttttct aattcataaa
     5401 cttgtctttc taacgtttta gctttgtgat acggagctaa taatttttgt aaattgtatg
     5461 tttcctcatc cacatagtcg tctgggttat tagtaatagg ctgtgcaaag accattagcg
     5521 tataatcata gtcttcatgg atgttctcac catattcaat agatgacaca attttaacgt
     5581 ctctcgtacc attagatact gggaaacgaa tataggcata atctttatca gaatcatatg
     5641 atactaattc gactggtaac tttttgtcac cttcataaac ttcaaatttc ttccatgttg
     5701 aagctgtctt taaacctaac tcaattactg gacctgtttt tgtaaaaatg acagttgctg
     5761 gttcaacagt actagcataa tgatagaact gtctttcacc tttatcattt ttcatttgaa
     5821 aatcaattgg tcgccaatta tcagctgtat gttctttatc gatgatagcc gggtttttaa
     5881 ttgcatcttg tagtgattca tctgctggtg gatactgttg attaacatcc gactgattac
     5941 ttgactcatt cgttttatcg ttagtattac cattagaatt tgtttcatga gctggttggc
     6001 ttgacgcttg atctgcattc gctgacgatt ttggttgtgc aggttgactc atatttgtcg
     6061 ttgcctgcgg ttgattatta gcattgttgg tcgttgatgt attttgatta gatgtattcg
     6121 tgtttgtttg attacttgcg tctgaacttg attgatcatt cgttactact gcatcatttg
     6181 tatctgattt cacaagtgaa ggatcgttat aaataggttt agcaaatact aatttagtat
     6241 aatcataatt tgtttcttct ccatcatcaa tttgagtcga agaaacaatt ttcaattctt
     6301 gtgtgccatc tgaaactggg aatcgaatat aggcatggtc ttctggtaca ggactatatg
     6361 atacaagtct cactggtaat ttttgattgt tttcatagac ttcaaacttt ttccatgttg
     6421 aagcagtatt gatgtctaat tcaacttctg ctttcttttt agtgtaatac acatctgctg
     6481 gatctttgat gctgaaaaag tgatagtact gcgtttcatt gtttttatct aataactgga
     6541 aattgacttg ttctcttgga cctatatcat gttctttatt ttctaatgca ggatctttaa
     6601 ttgcatcttt aagtgattca tccgctgcag gatagttttt cgcagtgatt actggttgcg
     6661 tagcaggttg tgtttgattt gtatccttag gttgctgagt tgtagttgca ttattatttt
     6721 gattttccga gattttatct gaagtatttg tattttctgc tgcttgcgct tgatgttgag
     6781 aagtaattaa aaatagtgta ctgacaatga ccgatgcaac gcctagagtt gattttctaa
     6841 tagaatagaa agaccttaat tttgggtgat gtttgttcat gttgttaaca actcctataa
     6901 gattatattt aattgataat aattatcaat atcaattatt agtgttaatt gtagcgcatc
     6961 ccaattaaat attgcaacct attttattaa aattttttaa tatgaatatt cattgcatcg
     7021 ctttcctatt cttcaaaccc actttttatc ttcatataca ttaattaacc accttcaaac
     7081 attgtcgtta gattcgccaa atggaatcta tttttagcac agcaaaaaac cgaactgctg
     7141 aaataatgca tctccaacag tccggtctat taaactattt acttatcttt attaaacaat
     7201 tgacatgatt tattagaata acccaattgc atgaccatca tcagtaacat ccatgtttaa
     7261 tgctgctggt tttttaggta aaccaggcat agtcatgatt gcacctgtca acgctacgat
     7321 aaatcctgca cctgttttcg cttctaattc acgaattgta atttcaaatc ctgatggtgc
     7381 acctaacaac gtttgatcat ctgagaatga atattgtgtt ttcgccatac atactgggta
     7441 attatcccaa ccattttctt taaattgttt taattgtttt tgcgctttac tgctaaacgt
     7501 tacttttgaa ccgccataga tttcagtcac aatcttttca atcttttgct ctaatggtaa
     7561 ttctaattca tataaaggtt taaatgaatt aggttgatca atgacttcta atacttcatt
     7621 tgctaagtca acgccacctt taccaccttt ttcccaaact tcagttaagg caattcgtac
     7681 gttattttct ttagcccaag attttacata ttctacttct gcatcggtat catgtataaa
     7741 tgcattaatt gcaacaaccg gttctacacc gaatttttta atattattaa catgacgctc
     7801 taaattaaca attcctgctt ttactgcttc tacattttct tcttttaaat tatctttcgc
     7861 tacaccacca tgcattttta acgcacgaat tgtcgcaaca acaacgacag ctgccagatc
     7921 aaatcctgct tcacgcgctt taatgtccat gaatttttca gcgcctaagt ctgaaccaaa
     7981 tccagcttcc gttacaacga tatcagctaa atcacgtgct gtttcagttg ctaaaattga
     8041 gttacaaccg tgtgcgatat tcgcaaatgg tccaccatga actaatgcag gtgtcccttc
     8101 aattgattgt actaagtttg gtttaattgc atcttttaaa atcattgcaa gtgcaccttg
     8161 cacttttaaa tctgcaactg taactggctt gcgatctcta gtgtaaccaa tagtaatacg
     8221 actaatttta tcttttaagt ctttaatact tctacttaaa cataaaatcg ccataatttc
     8281 agacgctact gtaatattaa agtcatcttc acgtggtaca ccatttgtag gtccacctaa
     8341 cccaacgttt acatgtctaa gtgcacgatc attcatatct aatacacgtt tccattcaat
     8401 acgtctttga tcgattccta attcattacc ttggtgaata tgattatcta taaacgcaga
     8461 caatgcatta tttgcagttg taatcgcatg gaaatctccg ttgaaatgta agttgatatc
     8521 ttccataggt aagacttgcg cataaccacc accagtcgca ccacctttga taccaaatgt
     8581 tggtcctaaa gcaggctctc ttaatgcaac cataacgttt ttatttaact catggaatgc
     8641 atcagctaaa ccaactgtaa ccgttgattt accttcacca gctggtgttg ggctcatcgc
     8701 agttactaaa acaactttcc ctttgttttc tcttggcgta attttattaa tgtcgatttt
     8761 agctttgtaa tgaccataag gttctaatgc atcctctgaa atacctactg atgcagcaat
     8821 atccttaatt ggttgtagtg ttgattgatt cgcaatatct aaatctgata aatgagtcaa
     8881 cttttttcgc ccctttttgt ttaatttatg catttataat atgtaagttg tagctaagaa
     8941 atttttactt acattcatat aataacgaac tgttaaaaac ttgtcgacta aatcgggtta
     9001 gcgctttcat ttttgcaata aattcactta ttaaagtttt gtattataaa acttttagcg
     9061 cttgatacta ttgataacta tatttttcta ttatttaaaa taatcatctt ccaaagatca
     9121 tattaaaaat aaaaagcaat ataaagatat gccataattg ttatgtcatc attttcaaat
     9181 gctttctacg aaatgatatg acacaagtta acagctcttt atattgctta tcgtaaagta
     9241 aacgattatt taaacattga catgaaatat gttgtcaccc tttattcttc gaaaaaaatc
     9301 ttcaataaca ttcatgtcat tattccattg tacttaaatc cccagcatct aaatttaatt
     9361 cccaagcttt taatacacgt ctcataattt tacctgaccg tgttttaggt aatttatctt
     9421 taaattcgat ttcacgtggt gctgcatgtg ccgacaaacc ttctttaaca aataaacgaa
     9481 tttcttcttt taattcgtct gttggttcat atccttttct cagtgcaaca aacgccttaa
     9541 ttatttcacc gcgaaccgga tcaggtttac caataattcc tgcttcggca actgcttcgt
     9601 gttcaaccaa tttagactca acctcaaatg gtccaactcg ttcaccagct gtcataatta
     9661 catcatcaac acgtccttgg aaccagaagt aaccatcttc atctttatat gccgaatcac
     9721 cagatacata ccagtctcca ataaaatatg atttatattt ttctggattc ttccagatac
     9781 gatacatcat tgatggccag ccttttttta tagcaaggtt gcccattcga tttggtggta
     9841 attcattacc tgcatcatcg ataattgcag cttgaatacc aggtaatggt ttgcccattg
     9901 agccaagctt gacgtccatc gttggatagt taacaatcat atgtccacct gtttctgtca
     9961 tccaccaagt atctaacacc gttaaaccgt atactttttt cgcccatttt ataacttcag
    10021 gatttaaagg ctcacctact gatagaatcg aacgtaacga tgacaagtca tatttctcaa
    10081 caatatcgtc accagcactc attaacattc ttaaagctgt tggtgccgta taccaaatcg
    10141 tcactttaaa atcttcaatc atactatacc actgttctgg tgaaaagcga ccaccagcta
    10201 tacaatttgt agcgccattt aaccatggtg caaaaatacc ataagatgtt cctgtaaccc
    10261 aacctggatc tgctgtacac caataaacat catcttcttg taaatctaat acatattttc
    10321 cagaaatata gtgcactaac attgcttgtt gaacatgcaa tacaccttta ggttgcccag
    10381 tagaacctga tgtataatgt aaaatcaaac catcatccga ctttaaccat tcaatgtcaa
    10441 attcatcgct agcagtttcc atcaaactaa tgaagtctat gtaattgtct tctacatcct
    10501 catctacgac aacaattttt ttcaagttcg gtaatttatc tacaggtact cgaggtaaca
    10561 atgccttatt agtaattaac actttagctt cactgttctc taatctatcc gcaactgcct
    10621 tttccataaa tgcttcaaat aacggcccaa caattgcacc aatttttaaa acacctaaca
    10681 acgcaaaata tagttcaggt gtacgcgaca taaatataaa tactctgtca cctttgtcaa
    10741 cttctgcatg ttcagacaaa acattcgctg ctttattaga taaccgttgc atatctttat
    10801 aagtatacga ttcttttctg tactcatctt tgtaatttaa cgctatttta tcccctaatc
    10861 cttgatctac atggcgatct atacattcat atgccatgtt catttttcca gtttcactcc
    10921 aagaaaatgc ttgttctacg tctttccaat caaaagtatt atatgtttct tcataatctt
    10981 taaggttatg tttaccttgc gctcctttat aaacttcgac tttcatttga aactccccct
    11041 ttgttatgtg aaaacgcttt ctttctcaat attatacata acatttctaa ttattcaaaa
    11101 tttttacttt tatccttttt ctagtattaa ttattgtaaa ttttctatat aatgaattta
    11161 atacaatcac gacgtcgatt gaggagttga aaatatgaat catttaaaga cgtatcaatc
    11221 cgaagattat tacattcatg acaagcaatt tgttattgaa ggtcctttaa catacgaaga
    11281 tttgaaagcg cttactttag atgcgcattt aaccgcattt agagatgctg aagatcagta
    11341 tgaagctttg ttagaaatta caacattacc agaaggtaga atttatgttg ctcgccaaga
    11401 tgaactcatt gtgggttatg tcactttcca ctatcctgat gaaattgagc gctggtctac
    11461 aggtaacctt ccatatttaa tcgaattggg ggcaattgaa gtcagcatca attttaagca
    11521 attacatctt gcagaaaagc taatacaact tagcctttct acaccagaat tcgaggatta
    11581 tatcgttata actactgaat attactggca ttgggattta aaaaattcaa agttagatgt
    11641 atttgactat aaaaaattaa tgcagcggtt aatggcaact ggtggacttg aaatattcgc
    11701 tacagatgat ccagaaataa caagtcatcc agctaattgt ttaatggcaa gaattggcaa
    11761 aaatattaca ttagaacagc aacaagcgtt tgatgatatt cgttatatga atcggttttt
    11821 cttttaattt ttggaatatc ggagggatta tatgcaacaa cattcatcaa aaactgcata
    11881 tgtttattca gataagttat tacaatatcg atttcatgac caacatccct tcaatcaaat
    11941 gcgtttaaaa ttaacaacag agctactttt gaatgcaaat ttattgtctc cagtacaaat
    12001 agtacaacct agaattgcaa caggtgacga attaatgtta attcataaat atgattacgt
    12061 cgaagctatt aagcatgctt cacatggcat tatcagtgaa gatgaggcta agaaatatgg
    12121 attaaatgat gaagagaatg gtcaatttaa gcatatgcac cgccatagtg ccacaattgt
    12181 tggaggcgct ttaactttag cagatcttat tatgtcaggc aaagtattaa atggttgtca
    12241 cttaggtggt ggtttgcatc acgctcaacc tggtcgagca agtggttttt gtatatacaa
    12301 tgatattgca attaccgcac aatacttagc taaagaatac aatcaacgcg ttttaatcat
    12361 agataccgat gcacatcatg gagatggtac acaatggagt ttctatgccg ataaccatgt
    12421 tactacttat tctatccatg aaaccggaaa gtttcttttc ccaggctctg gtcactatac
    12481 tgaacgcggt gaagatatcg gctatggaca cactgtaaat gtcccacttg aaccgtatac
    12541 agaagatgca tcatttttgg agtgttttaa attaacagtt gagcctgtcg taaagagttt
    12601 taaacctgat attattctaa gcgtaaatgg tgtcgatata cattatcgtg atccactaac
    12661 tcatctaaat tgtacgttac attcattata tgaaattcca tattttgtaa aatatttagc
    12721 tgattcttat acgaatggaa aggtaattat gtttggtggc ggaggctaca atatttggag
    12781 agtcgtacca cgtgcatgga gtcatgtatt cttaagttta attgatcaac caattcaaag
    12841 tggttattta ccgttagaat ggattaataa atggaaacat tattcatctg aattattacc
    12901 taaaagatgg gaagatcgtt taaatgatta tacctatgtc ccccgcacaa aagaaattag
    12961 tgaaaaaaat aaaaaattag ctttacatat agcgagttgg tacgaatcta ctcgtcaata
    13021 agtaacctaa tctgcaacga ttttaaaaga taaataaaag gcattcttcc aacacccata
    13081 taatttgggt cgttagatga atgcctaatt ttgtgaattt attttgtagt tcctcggtat
    13141 tcaattctgt gaggtaaaac tacatttggt tcttctatct tttcatcgtt catatatttt
    13201 gttaataagc gcatccctac tgcaccgata tcatataatg gttgaataac actagaaagt
    13261 tgtggtctaa ccatctcaac taatcgtgta ttattgaaac taataatttg taattcctct
    13321 ggaactttaa taccagcatc cattgcacta tgcataatac caattgcttc ttcgtcgctg
    13381 atacataaaa tggcatctgg caaattgcct ttcattttag caaaagcttt tacgccttct
    13441 ttataacttt cagcaccaga acaattcaat gtatcaccta attgaaggcc atttttattt
    13501 aacacttcag ttaaaccttc taaaacatct tcttgagctt ttttagaatg ttctccacct
    13561 actaaagcaa atgatttagc gcctttttca attaattctc ccgtaatttc tttcgcagct
    13621 tcagtaaaat caatattaac tgatgctata tgtgcatcct taccatttgt tcctgatact
    13681 actacaggta cagatgattg atttatcaat tctttcattt cttcagtaat tgtaccacca
    13741 aggaaaataa taccatcaac ctgtttactt aataagttat taaaaatttc tttttccttt
    13801 tcaggatcgt tatctgaatt tgaaataatt gagtgatatt tatacattgt tgcaatatct
    13861 tcaagtccac gagcaagttg tgaataatag atattagata tatctggaat gatcacacct
    13921 actgttgttg tctttttact agctaaacct ctagcaacag catttggacg ataattcaaa
    13981 cgcttaatga cttcgttaac tttattttta gtttctgctt taacattttg gttcccatta
    14041 acaacacgcg acactgtggc catagagaca cgcgcttctc ttgctacatc atatatagta
    14101 actgtcataa tttcctcctt gtaaacgttt tattcattat aataacatgt tttcatttca
    14161 ttttcatagt ttaccatatt ttaatttaca gtaacatatt tttgtttgga aaaatttagc
    14221 gaaaagcttg aaataaaaac aaacgctaaa tgataacgaa cgatatattt taattttata
    14281 taaacttttt tcatttttaa ttgtaatgtt ttgagaaagc cttttcaaac atcaattgca
    14341 tttgttgaaa aatgttcaca tttcagcaac aaatgtgtga atctattata ttttacagat
    14401 aattcatagt tataatttta attactgcta tcagtcataa tctttaataa ttgtgaaatt
    14461 gaacaagtgt cgaagtatta taacaatcgt taagtgcagt atacctttat ttctatacaa
    14521 aaaataatag ccactctaaa agtaatatac tcttagaatg gctgtaagtt taaaattgtc
    14581 gattcaaaga taatattcta cttcaacatg acatattagt taagtagtct atagtttcct
    14641 tggaatatta ttttaacttt ttagcgttat ataaatcagc taaaggcttt aattcatcat
    14701 aaaatgcttg gaattcatct aaatccattt gttgacccgc atcactaagt gcaacagatg
    14761 gatctggatg cacctcagcc ataactccat cagcaccaac tgctaatgct gctttcgcag
    14821 ttggtaacat gatatcttta cgacctgtac tatgcgtaac atctaccatg actggtaagt
    14881 gtgtaccttg ttttaaaatt ggtactgctg aaatatctaa agtgttacgt gtcgcctttt
    14941 cataagttcg gattccacgt tcacataaaa taatgttttg attaccttgt gaagcaatgt
    15001 attcagctgc ataaacaaac tcttcgattg tagcagataa accacgtttt aatagaatag
    15061 gctttttcgt acggccagct tcttttaata actcgaagtt ttgcatatta cgtgcaccaa
    15121 tttggaatac gtctaaatac tcatcagcca cttcaaaatc atttggattt acgatttcgc
    15181 tgacaacatt taaatcatat ttatctttaa tctgtttaag tattttaagt ccttcaacac
    15241 ctaggccttg gaaatcatat ggtgatgtac gtggtttaaa tgcaccgcca cgaataaatt
    15301 tttcaccttt agcatgtaag tttttagcaa cagcttcaac ttgttcaaat gattcaactg
    15361 aacatggccc aaatacaaat gatttattgc cgtctccaat aatgccccca ttatcaaatg
    15421 ttacaatcgt atcttcaggt ttcaacttac gtgatacgta taagtgtttt tcattttcag
    15481 atttttgtaa atctgtagag gctttaaaaa ttgctttaaa taattgctta attgtattat
    15541 cgttaaatgg tcctttgttg ctatcaatta agtcgttaag catttctttt tcgcgttgtg
    15601 gatcatagat acgtgtacct tgttttaatt tttcctcccc aattttttgt gctagttcac
    15661 cacgtttaga taataaatct aaaatttgat gattcagtga gacaatctca cttctgtatg
    15721 attctaattt attactcatc cttactcacc tctacgaatt atttcaagta tattccactt
    15781 taaagcaata aaatataatg ttaaaaaata ttctaacaat atcatatgta tagttcaacc
    15841 ctaaattgac agaaaataat caattttcta attatatgat tcgagactga catttcgatt
    15901 ttctcagtca ttattggaaa gttatattct atattgatat ttattagcaa atgttaatca
    15961 attaaataag tgtcattatt atagcttatt ttgagtcaac attactgctt ttaagaaaaa
    16021 ttttcgtttc tatcttctat tataaatcta aaattctcat acattcaacc taacgcttaa
    16081 taaaaattaa caacctttgt atattaatat aaatctatag tgaacatcac tcaccaacat
    16141 gagcggctat atttgaatta gtgaacgtca ttgtaccttc taagattcat tgtttatttg
    16201 attatcgaat atttttccat cttcagctta aaatgtgcaa tataactatt gttatctaac
    16261 gatgtttcaa acagcataaa tacatgaaat gatcgcgttg cctttcaaaa taaactgatg
    16321 atatcaaaaa aggtaagcac ctgaatgcct accttttatt ttgaaattca atttttaaaa
    16381 atataataca tagcttactg ctatgattga ttattcaacg attttagtaa tcttagtcat
    16441 tgaatgtacg tttctctatt ttactattag ctttttcaac tttagcattt ggcgtttttg
    16501 atgcattgga tgatttagca tttgttgttt ttgaattctt attactagtt tgattattct
    16561 tttgagttaa cttacttgaa ctactttgtt tctttgcacc ttgtgatgat ttcttattat
    16621 gttgcttttt ctgacctgaa gttttatttg tagatgcttt tgatgcattt cgtttatttg
    16681 aaggtgttgt ttttttagat tgtttacctg atttcttgtc aacagctgta ttattagttg
    16741 ttttttcatc agctttacgt gtaataacac cattttcaaa tttagcttct ttttgtttaa
    16801 cagtgtcttt attatctata ttaaccgtct ctgtctctga tacatcattc tttttagtaa
    16861 ctaattgagg aatttctttc aagtcatttt tagcaactgg tttttctgca aataacgctt
    16921 cagttaattg actctctttt gaacctggtg ttaatttagc ttgcttctgt tttgcagcgt
    16981 ttgctaatct ttcagcttgt gactctggtt ttgatacttc tacctttgct gcacttgcat
    17041 ctttagttga tgtgtcactg tctttctctg cttgtgcttc ttttttagct tcttgaacct
    17101 cttgtgcctc ttgtgatgta tcacttaaat tatttgcact tgcttcttct tttatcgctg
    17161 cttgttgtgc tttcaatgcc actgcttttg gttcttcatt tgatacagct gcacttttat
    17221 ctgtttctgc ttgtgcttct tttttagctt cttgaatctc ttgtgcctct tgtgacgtgt
    17281 cacttaaatt atttgcactt gcttcttctt ttattgctgc ttgttgtact tttaatgccg
    17341 atgcttttga ctcttcattt gatacagcca cacttttatc cgcttctgct tgtgcttctc
    17401 ttttagcttc ttgaatctct tgtgcttctt gtgatgtatc acttaaatta tttgcacttg
    17461 cttcttcttt tatcgctgct tgttgtgcct ttaatgccgc ttgctcattt ttagatttgt
    17521 ttaaaaatcc ttcaacacgt tcttttgtat aggcaaccgt ttcttcaagt tgcgtttttc
    17581 tttcttcaaa cttttgcgac agttcttgtt ctttgacttt taaatcatct gctttttgat
    17641 aaactttatt tttaaaatac aaacctaaag ctgaaccaac aagcgcgcca gttataaaac
    17701 taacaacaaa atctttacgg tttggtagtg gttcattttg ataagtgtgt ttatttttta
    17761 atgttctttt atcattttgt tgctgcgtca tttgtatatc ctcctataac aaatgcactt
    17821 aaataagtaa caacctcatt taagtgcatt tgtttaatta ttaattattt atctactcta
    17881 gaagtatagc tatgatttgc atcagttgct acattattag ctttgtaatt tgcacttcca
    17941 cgacggtagt gtctattttg ccatttgtct gcaatttcca ttgcaacatt tgaccattga
    18001 acaacttgtg agattttatc ttcattttga gaaatattat gtgtaattga atttgttaca
    18061 cgatctacag agctgtttaa cgtttgtact gagtcaccga tacctttaac agcatctaca
    18121 actgagttta aacgatctac tttaccttgg atatcctcag ttaaacggtt tactttatga
    18181 agtaaatctg ttgtttcacg agtaatacct tgaacttgac cttctacacc gtcaagtgtt
    18241 tttgcaacat aatctaagtt tttcttaaca gaatttaata cagctacgat accgatacat
    18301 aaaattaaga atgcaatcgc agcgataatt ccagcaattg gtaaaatcca atccattaaa
    18361 aacgcctcct aattaacatg taataatgtc attaataata aatacccata ctactctatt
    18421 ataaacatat taaaacgcat ttttcatgcc taatttatct aaatatgcat tttgtaattt
    18481 ttgaatatca cctgcaccca taaataaaac aacagcatta tcaaattgtt ctaatacatt
    18541 aatagaatct tcattaatta acgatgcacc ttcaatttta tcaattaaat cttgtatcgt
    18601 taatgcgcca gtattttctc taattgatcc aaaaatttca cataagaata cacgatctgc
    18661 tttacttaaa ctttctgcaa attcatttaa aaatgcttgt gttctagaga aagtgtgtgg
    18721 ttgaaatact gcaacaactt ctttatgtgg atatttcttt cgtgctgttt caattgtagc
    18781 actaatttct cttggatggt gtgcataatc atctacaata acttgatttg caattgtagt
    18841 ttcattgaaa cgacgtttaa caccaccaaa cgtttctaat gcttctttaa tatttgtaac
    18901 atctagcttc tctaaataac taatcgcaat tacagctaat gcatttaaaa ctgtatggtc
    18961 accatattgt ggagacagga agtgatcata aaactcacca tccacataca catcaaaagc
    19021 agtaccttta tccgtaattt gaatattttg agcataaatg tcatccgaat ctttaaatcc
    19081 ataataataa attggaacat ctgcttcaat tttacgtaga tgttcatcat caccccaagc
    19141 aataatacct tttttaacat tatgtgccat ttcttggaat gcatcaaaaa catcattaat
    19201 atctttaaaa taatcaggat gatcgaaatc aatatttgtc ataattgcgt aatcaggttt
    19261 ataacttaaa aagtgacgtc tatattcaca tgcctcaaaa gcgaaataat cactttcagg
    19321 caatcccata cctgtgccat caccaattaa aaatgaagtc tttttatcac cattcataac
    19381 atgtgataat aaacctgttg tagaagtttt accatgtgca ccagttacag ctactgaagt
    19441 atattgatca ataatctgtc ctaaaaaatc attataactt acaacatcta atttcaattg
    19501 atgtgcacgt actatttctt catggctact cgcgaatgca ttaccttgta taactaccat
    19561 atcttctttt atgttattag catcaaatgg taatattttt atccccttat ttctaagagc
    19621 aacttctgta aatacgtagt tctcaatatc cgatccttga acttcatgtc ctaaatcatg
    19681 catgatttgt gctaatgaac tcatgccaga acctttaatt ccgacaaaat gatagtgtgt
    19741 cattatataa aactccttac tcataattat tctttattta aatctgcttc cgtaacataa
    19801 acatcccttg gttttgaacc attagcactc gaaacataac cgagttgctc taattgatcg
    19861 ataattcttg ctgctctatt atagccaatt tggaaatgtc tttggattaa tgatgttgaa
    19921 atatgtcctt cattaaccat aaatgcacaa acatcatcaa ataattcatc ttgtgattgt
    19981 gtttgtgttt ttttcaacaa ttctttttct tcaaatagat agtccggttc tctttgttgt
    20041 ttgataaaat caacaacatc atcaatttcg tcatcagaaa caaatgtacc ttgaactcta
    20101 atcggtttat tcataccgct accaagatat aacatatcgc catatcctaa caagcgttct
    20161 gctccaccac tgtctaatat cgttctcgaa tctacacttg atgataccat aaatgcaatt
    20221 cttgttggta tgttggcttt aattaaacct gtaattacat tgacagatgg tctttgcgta
    20281 gctactaaca tatgaatacc acatgctctt gctttttgag caattctagc aatagactgc
    20341 tcaacttctt gcggagccat catcattaaa tcagccaact catcaattac aatgacaatt
    20401 tttggcattc tttcatcata tggtgctttt ttgttaaatg ctgttatatt acgtacatgg
    20461 taatgtgcaa ataacttata acgtcgttcc atttcttcta cggcccattt taaactctgt
    20521 gtagctgctt tgacatctgt aattaccggt gcaactaaat gtggcaaacc attataagga
    20581 gctaattcaa ccatttttgg atcgataagt aataatctta attcctcagg gtgattttta
    20641 tatagtaaag acatcaaaat actattgata caaactgatt tccctgatcc agttgcacct
    20701 gcaattagtg cgtgtggcgt tttagcaata tccataagta atggttcatt attaattcta
    20761 taccccatcg caactgttaa tttagattca gcatttttaa aacttggaga ttcaataata
    20821 gaacgtaagt tgactgtcgt tggattttgg ttcggaactt caataccaac acgactagtt
    20881 cctggaatag gcgcttctat acgaatatct ttcgctgcca atgccatttt aatgtcatct
    20941 tgtaatgccg taattcttga aactttaaca cctttttcaa ctgataattc aaatcttgta
    21001 acacttggac cttcagttac atcttgtact tctgcaggta cattaaagta aaataatgcg
    21061 tcattcagtt ctttcttttt atctgtaatc cagtcctcgt ccgactcaat aacttgtggt
    21121 tcttctagta atgaaacact tggcaattta atatttgggc ctttacgaat catcggctta
    21181 gatgtttgta cagcttgatt tgttgcaaca tcttgttggt tcgtccgagg tctattttca
    21241 ttagctgtat cttcattttg atttgaaaat gaaggctgta aacctttttg ttgatcatca
    21301 ttatcttgtt gtccactagt attgtttgga tgtgttgttt cttcgctttc ttcagttatg
    21361 tcgcttactt ctgaaactga agacgaagtt gattgatcaa cttgctcatt ttccaattga
    21421 ttatcatctt ggctttcttc aaatatttcc gtttgagttg aatcagcaga aggtttctgc
    21481 tctgaatatt gttgtgcatt ttgataatca ttttctgttt ctgcatgacc aataagttga
    21541 ttgttctcaa cattgtttga tgtcatatta tttgttttat atgcatttgt gtttgactct
    21601 tgtgaatcag atcttgatga tggtgcggct tgactcgcag gcttgctttc actcacagct
    21661 tgtttacttt gtacaggctt taattcaggc acattgactt ttgaatgctt tttacgatcc
    21721 atcatacgct ttttatcaga tggcgtcatg acaacattaa atggtctttt acttaaagtt
    21781 gaaacctttt cagtctgttt ctttggattt acgttttcaa tagttttctc ttcgacattt
    21841 tgttcacttt cagctgcttc gttttgcaca ttttctgtaa tttctgcgtt atgcttttct
    21901 atttcattca tgcttgaatc ttccacaaca tgaccatcat tcacatcatt cgttttcaat
    21961 gagttgacat ttaagtttgt ttggtcatct tttttatgac gcggtgctaa ttcaatttca
    22021 ttatcaaccg ttttatcgat attattaact tgagattcag ttactgcgtg ctcttgcgtt
    22081 ttaggagcgt ctacatgcat ttcagacgcg tttctattgg tattatcttc gatatttgaa
    22141 gtagtatcct catctacttc tgtatcattt aattcataaa attctgcatc atcgatttga
    22201 cttcctgaat attcttcttt attcgttgct ccatcttctt ctgaatcagc aattaatctg
    22261 gattgatttt ttagttcatc tttatcattt acttcaacgt tatgttgtag tgctgattga
    22321 tgttgagacg ttacattcga aaccgtaact tcatcatctg acaattgttt tgttgtcgat
    22381 acttgattca aactaacttc ctcataattg tatggacttt catctacatg agtgtcatta
    22441 gtgtcttcat tttgtattga cgcttgttta ttttcatcat ttgatacagt ttcattctct
    22501 atgccatttg tatgaagctg actagcatct gtactattat ctgttaagtc actatcatca
    22561 tttaatgaac tatcaccaac atagcgttcc gcttgtttag catacatttc atcaattgca
    22621 cgttgtattg catcttgctc ttcgttttta tgttcttcac gcttttgttg caacgctttt
    22681 ttaaatcgac gcttttgaag cactttacgt tctcgttcac gtctaatttc ttcaacaatt
    22741 tgtgaagcat aaatattttc aattttgata gtattatcaa cttttgaata attaggcatt
    22801 gattttgttg ttgatgatac attttcatca gatgatttag atgcagttcc ttgtttgaca
    22861 acactatcat tttgtttttc ttgttctaat tgtttatttt gagacgtttg cgtcttagct
    22921 acatatttat catatttttg tttatctgac tcaacttttt ctgaaggttt acttacaggg
    22981 atacgaccat tttctaactt tttaggtttc attgtgccaa aaatagctga cggtacctct
    23041 gaagtcttga aactttcttt gtgataatct ggagttgaat ctttagcacg atgatttgta
    23101 ttattagaat acatattatg tgtttttgac ttgtgcgttt ccttctcaat accattaatt
    23161 gcagaaacat atgtacctgg cttattcgta tggtaatgtg aatgatcttt atattttata
    23221 ctttgctgtg atattttaga attcccacgt tgttcactat aattttgttc ttcagttgtt
    23281 tgatttcttc tacggcgatg tcgtttttgt gaacgagaat cgtggctttg tttgcgatag
    23341 tctcgatggt attgttcttt ttcatctgaa atagtatctg cagattgttc aacattttca
    23401 ttttcataag ctacgctcat aggaaaacgg aattttcccc tcggacgact ataaatatca
    23461 ttattttgag gcagtaatga gtcatgatcg ttatctatat tttgtgattc ttgacgtctt
    23521 tttttctttc tatgaatcaa gtcatcattt gaatcattat cttcgccgaa taatttatca
    23581 aaccagctca tattttcact accttcctta attattcaaa aaatgcttgt ccaatttcat
    23641 agctgtcatt taataccata ataccttttt cttcaggtgc attaggtaaa ttcaattctt
    23701 tcattgaaca aatcataccg cttgaggcaa caccacgtaa ttcagcatct ttaattacca
    23761 taccgctagg catcactgca cctactttag caacaacaac tttctgtcca gcttcaacgt
    23821 taggcgcgcc acatacaatt tgtaatgtgt catttccaac gtttacattt agtacactta
    23881 atttatctgc atcaggatgt ttgtctttag tttcaacgta gccaactaca aatttcggtg
    23941 atagatcagc atttaattta taatcaaaac cagcttctga aatacgcttt tggaatacat
    24001 ttacaagttc atcagttaat ttaatatgac ctttttcttc aattgttata tcttttgaaa
    24061 tttcaaaaat attataacct acaacattac cttcattagt aatttcaaca acattacctt
    24121 ttttattgta gtttaattca ccttcaactg gttcaatttg taaaaatgcg acatctccta
    24181 catatttagg attgtaaaat aaattcatta tgacaaaact ccttatccaa ttatttctat
    24241 ttatctttat taaatttacg acgatttgct tctaaacgct gaatcacgtt tggatctctt
    24301 ttttgtttat tatttttacc taaaataaat atcggttcaa gatgaccctg tttatatcca
    24361 aaggataatg atgtaattgg aactagacct ttagtgaaaa attccattgt taaatgtgcc
    24421 atcacatcat atcctgtttt attgcgtata tctgcaataa ttaacacatc ttggtgtggc
    24481 actgctacga gcatttcgcc ttgacattgt gcctcaattt catttaaaaa tgcagtattt
    24541 agtatcctac ttgcatcata cccgtcattt gagttaataa aataaaaaat attacctttt
    24601 acttcatcag tcgtatatga atttgacaat tttctaacat taaacagaga catttctctt
    24661 atttgttgtt cagttaactt caaatcctct aacatgcttt cgtcaattag acgatatgat
    24721 ttccctaaat cgactgcata ataaactgct gtttctgcag tatgctcatc atagataaaa
    24781 ggaacacctt gtttagtttt tttatcaaag ctagtcgctc taatgacagg cataatttga
    24841 ctagatgata tactctcaag ggttttatct gccatttgtg caatagcttc atcaacgtaa
    24901 taaacaattt catctacaat tttttctttt ttatcttcat attttgcgac tatagcgtta
    24961 agtttaatcg tgataccttt gttattatct gttcgataaa tacgcaaagt ttcttcttca
    25021 cgattaaatt taaaatcaac gtctaaatgg cttaaacgtt cctttaattt atctctcatt
    25081 tgaaaggtat tcatatgtaa cactcctaat ttcgcacctt ataatagttt acaataaatc
    25141 aacacatagt aacagagaaa aacgagtatt accccgtttt tctctagtct aaattacaca
    25201 tattgagcta aaaatgcatc tatctgttca attgattttc gttcttttcc aatataactt
    25261 ccaagcagtt caccattttt atatactaga aaacttggaa tccccataat accattttca
    25321 atacaaatat ccataaattt gtcacggtct actgatacga agtcaaacat aggatatctc
    25381 gcttctaatt ccggtaaatc tggttctatc actctacaat ctggacacca gcctgcagtg
    25441 aattcaaata ctgtagcacc ttgttttaaa gattcaaatt gttgttctga ttcaagttgt
    25501 ttcattttta tgtctcctta attaatgatt atatataact atttagagat aatagttgtt
    25561 attacccgat tatttatatt gtaatgtttc tatttgatta ttatctaaat tacaaatggc
    25621 ttctgaaagt aaagatctag ctgcaaaata gtctcttata tcaaatactg agtctgtact
    25681 atgaatatat cgtgcacata caccaataac tgcagtcgga ataccaatat tagctttatg
    25741 aatttctcca ccatctgttc cacctggtga catatagtat tgatgttcaa tgtcatgtgc
    25801 ttctactaac tttaataaat aatctctaaa tacaggcttt aaaatcattg taccgtcttt
    25861 tatgcgaatt aacgtccctt taccaagttc accagataat ggttggtttc ctttaacgtc
    25921 attggcaggt gaacaatcga ctacaaatgc aacgtctggg tctatcatct ctgcagatgc
    25981 tttcgcacct cgtaatccaa cctcttcttg aacatttgcg ccaacataca agtctacatc
    26041 taattctata tcttttaata attctagtat ttcaattgcc aagacacaac cataacgatt
    26101 atcccatgct ttagcactat atcgatgttc agataactgt gtgaatggcg tgtgaggtac
    26161 aattgtatct cctatatcta ttccgcgctc acgcacctca tcttcatttt gagcacctat
    26221 atctaatgtt aaatctttaa tttccggtgc accttcacta ccagtacgaa aatgtttagg
    26281 tatattagaa acaacaccga taattttatc gccatttcta tttttaatta ctaagcgttg
    26341 tccttgccaa atatcatttg caacaccacc taaatttgtg aattgaatca ttccattttt
    26401 agtgatattt gtaatcataa atccgatttc atccatatgt gctgcaatca ttacacgttt
    26461 tgcatttgga tttttagatt ttttcacacc aaaaaatcca cccatacgat tttcaataaa
    26521 ttcatctaca tacgtcgcca tttgctgagt catataattt tttacttctt cttcaaaacc
    26581 tggtgcccca tgaagctcag ttaaagtttg aattcgttgt aatgttactt ttttatttat
    26641 gttcataaaa gttctcactc cttataagtt attatatcat cttcaatatg gtaaactaat
    26701 gatatgaatt tgaaatcaag ggagcataaa tgatgactaa actgaaatat ataattccaa
    26761 caataattgc agtagccatt gtaattattt ctaccatttc aatcatccaa tttattaatc
    26821 gtaaacgcta taatcccgtt aaagtactta atgaagtaaa atcatatttt atgaatgtca
    26881 aaggctcata tatcgtttat gaaccattcg ttcatcctga aactgataaa taccgtttag
    26941 tttatcaagg tggaattaca actattaaaa atggtcaaaa tattcattat gatttttatg
    27001 cagatgcata tactggtgaa gtcattaaca ttgtagagcg ttaatacgaa ttttatccat
    27061 atttgatttg gatcgtaaaa cttaaaaatg agccacaccc taattagtaa gattggatgt
    27121 ggctcatttt tttatttttg aaaatttgtt tagtaataca tctttatttt agttattatc
    27181 aactaatgtt tcacgtaaaa tatatgcatc tatgttttca ccatcatcgc tgtattttac
    27241 agcaaagtag ttttcatcat gataaaacaa gaaccaatat tgttgctgaa taaaatatgg
    27301 tatcatgcgt tctttttcac gaatcgattg cataggataa tcatcatatg ccgttaccca
    27361 tagaggattt ttatgtgcag tagttgggaa tatatcaccc atatgaactg ctttatctcc
    27421 ttgactttca atcgtaataa tcgtgtggcc aaagctatga cctccactat gttgcatctt
    27481 gatacccgga accggttcaa aatgtttttc gaataaaatc aacttgttac tataatcgcc
    27541 tttattctta tcccagtaag ttgatttact tcttatatta ggtgcaataa actcatgcca
    27601 ctcatcttgt tgcacaacat gaatcgcatt ttcaaaaatt gcatgtcccg cttgatcagt
    27661 caaaccggca gcatgatcaa aatgcatatg tgtcattagc acataatcaa tatcctttgg
    27721 cgttaaatta taatttgcca aatcagcaat tatatgactt tcttcatcta ctccaaaatt
    27781 acgtaattgc ttttcagata atttaccatt accaataccc gcatctataa tcaaattata
    27841 ttgagccgtt tgaatcaaaa ttggatgtgt cggtaaattg atttgatttc gttcatttgc
    27901 attgtattgc tttgaccaca acggcttcgg aacaacacca aacattgcac cgccatccat
    27961 ttttgtattg ccaccattta gataatgaat agatatatcc ccgatcttca taacatcacc
    28021 tattctttct gtattcgtta ttacaattag catgtattta ttacatcata tcactattca
    28081 taaatgcgaa caaaaacgaa acgccccaca ctaatacact tctaactact tataaagatt
    28141 aatgcaatca tattatatgt aaatgcatca taaccatcgg cctgtaattt taaattaata
    28201 attaaaattt acaagtaaaa tgcaagcttt attcttttaa atcaaaggta tttagtataa
    28261 cattgtttat aggcgcatta tctcctttag ttatttgttt agtcactttt aattatagag
    28321 ataattgcgc tttttttata ttcaaaatca aaaaatcgga cagatgaaaa gtaaaatact
    28381 tttttccatc agtccgattt attatagaac ctttatctat agaaccatta tagtacgaaa
    28441 aaacacttat gattgtatgt gtacataccc tcataagtgt tttatttttg tgaatggaat
    28501 ttcgcttcca tacgataaat acgtgaccct ttatccgaaa atttcttttc atattctgtt
    28561 aaaatattac tgccatcgtc ttcttgatgt aaatttagat ttatttttgt aaaatacatt
    28621 ccaaattgag acatactttc taaactgtag gcaaatagtc ctctgttatc agttttaaaa
    28681 tgtaaatctc cttcatcatt taagatttgt tgatacaacg ctaaaaacgt atgatacgtt
    28741 aaacgtcgtt ttgcatgacg attttttggc catggatctg aaaagttcaa ataaatacgc
    28801 gaaacttcgc cgtctttaaa atattcattt aattcaatgg cgtcattaca aataatcttt
    28861 aaatttgtta aacccatctc tttaacttta tccaatactt tataaacgat acttttctca
    28921 cgttccattg aaatatagtt aatatgagga ttttgagcag ctaatgttgt aataaactgc
    28981 cccatacccg aaccaatttc aatgtgtatc ggttgcgttt tatcaaacca ttcagtcatt
    29041 ttccctgcat gttgaccttc catgtcaacc aattcaggat gatcttttaa ataatcttca
    29101 gcccatggtt tgtatcgaac tctcatattt tattctcctc ttaaataaac atgttactat
    29161 tcataacttc atttaggaat ttaagccaag tgttcatatc cttatatctt ttttgctctt
    29221 cataccattg aacaagacct atagattgaa ttaccgtata ccatttcata cgtttattta
    29281 aattcaagct ctcttgaaca ccatatgttt caagccattc agaccattgt tgttgtggaa
    29341 catagttgta aagcagcatt ccgatatcaa ttgccgggtc tgcaatcatt gcaccttccc
    29401 aatcaactaa aaatagttca tctcgatcgg ataataacca attattatga ttcacatcac
    29461 catgtacaac agtgaaaaaa cgcgaatcta aactcggtat atgctcttct aaataggtta
    29521 atgattttct cacaatatga tgtgttaaaa cttctcttga taaagaggca ttaattttat
    29581 taagcataat ctcaggagta ataggttcca tttccatacg ctttaacata cttaataaag
    29641 gtctagaatt gtgtatcttc tttaataaat gtgcaactct tgtttgcttc atttcgtttg
    29701 aagatagttc acgcccattt ttccaatgtt gtgctgtaac aacctcgcct gtttctatgc
    29761 gtttcgtcca tactaatttg ggcacaatac cttctgctga taatgccgca ataaatggat
    29821 ttgaatttcg ttttaaaaac aacttttgtc catcttgttc agccatatat gcttcaccag
    29881 atgcaccacc tgctgaatca agtgtccacc ctaattgata aaactgctcc aactcgtcca
    29941 cctcactttc aattagaaaa tggctctaga aataggtttt tcaagagcca tatattctaa
    30001 tttataacac catactggta caaatattat gtccagataa ttattgtaaa tcctcaacca
    30061 atgcctacat tacacgacta attttaaatc gtaatgtctg tcattgacac catacattct
    30121 atagtcactt acttgacata taatgttacc gtgtctaaaa ctacatgttt ttgaatctct
    30181 gtaggcgata aactctagtt ttcaaaataa ttgctatccc attttcatgg ttagcataaa
    30241 tttatgaact gtaacattta cgtacttagt aaaatatgat gcacatcata tttgtaactc
    30301 atagaaaatt ttataatttt tatcattata tttcaactga aaatgagaaa caaaatggca
    30361 ctttttacta atatgtgttt tctaaacaac acttttaagc ttcgttttaa attataacat
    30421 aattcactta cgaaagttga taaatttaag taatttaatc taaaaatatg atgaaagaat
    30481 tttaaatact gtgtgactct atatactttt caaatccttc ttgtagttga cgtgtaattg
    30541 ggccaacttt accatcatta attggttcac catctaattt aataacaggt gtaacctcag
    30601 ctgaagtact tgaaacaata acttcatctg cgtttttcaa gaaatctaca gtaaacgttt
    30661 cttctttaaa tgggatgtta tagtcttcgg caattttttt aattacaatt cgtgtaatac
    30721 cattaagaat atagttgtta atcggatgtg tataaatcac accgtcttta attgcataag
    30781 cattacttga agatccttca gttacagttt cacctcgatg ttgaattgct tcaactgcat
    30841 tatatttcac agcatattct tttgctaata catttcctaa taagttcaag cttttaatgt
    30901 cgcaacgtaa ccatcggata tcttcaacgg taacaccatt cacaccattt tctaaatgat
    30961 cataaggacg atcataactc tttgtataag caacaattgc tggttctact tcaggtgtcg
    31021 ggaagctatg attcctttca gctacaccac gcgttgcttg aatataaatt gccccagttt
    31081 caatttgatt catatcaact aatttacgag atagttcaat taattcttct acagaataat
    31141 ttaaatctaa accaatctca ttggcactac gtaaaaatct ttcataatgt tctgttactg
    31201 taaataactt accattatat actcgaatgt attcataaat accatcgcca aatacgtatc
    31261 ctctgtcgtt gtatgaaacc tttgcttcac ttggacttac aaactcacca tttaaaaaaa
    31321 ttttttccat atattattcc tccacgcata atgaataaat tgcttctaag taaatactag
    31381 ttgcgttaaa taactgtttt ttagtgatat attcattttt ctgatgcatt aaatcttcag
    31441 aatcactaaa cattgcgcca aatgctacac ccttgtctaa gtttctcgca taagtaccgc
    31501 cacctatagt ataaggttca gtcatatcat ttgtttgatt tctatatgca gtaactaact
    31561 tttgtacaaa aggatcattt ttatcaacat aatgtggtgg ttggacttta cctaatttca
    31621 cttcaaagcc atattgttga atctcatttg caaaacgatc catagctttt tcaaattcaa
    31681 atccttctgg gtagcgtaag ttgataccga aaagacctgc gttttcatta tcatatgtaa
    31741 taacaccaat gttagttgtc acgtcaccca tgacatctgt atggaatttc attcccatct
    31801 tttcaccaaa atctgaatta aataagtagc gattactaaa tgctacaaac gcttgtgcat
    31861 tattatcaag atttaatgat gctaagaatt ttagtaagta aagacccgca ttcacaccga
    31921 tagatggatc cataccatga accgctttac cttcaactgt taaaactaga atgccactat
    31981 caacagtact atcaccttgt aaatgatttt gttctaaaaa gtactcaaag tcttgaataa
    32041 catctgtcat attttcttta acaagcactc ttgcttctgc atgatcaggt accatgttgt
    32101 aacgttcacc agatttaaaa gttattaatt cataatcagg ttcatcttga tcttcagtaa
    32161 gtttattttg aactaaatca aatgttgtaa tgcctttttc accatgaata catggaaatt
    32221 ctgcatctgg tgcaaaacct aatgttggca tttcttctgt tttaaaatag cgatccgtac
    32281 atttccaatc agattcttca tccgtaccaa taatcatatg aatacgtttc ttccaatcca
    32341 cattcatatc ttctaatatc ttaattgcat aataagcagc aattgttgga cctttgtcat
    32401 caagtgtacc tctagctatg atagcatctt ctgttacaac cggctcgaac ggattactat
    32461 cccatccatc accagcagga acaacgtcaa catgacataa gatacctaat acgtcatttc
    32521 ctttacctgc ctcaattctt cctgcaatat gatccacatc acgtgttgta aatccatctc
    32581 tatgtgcaat ttcatacatg tagtctaatg ccttacgagg acctggacca actggtgcgt
    32641 cttctgatgc ttttgcatca tctctcacac tttcaattgc taataatcct tttaagtcat
    32701 taatgatttg atcttcgtat tgttgaactt tttctttcca cattcgaaat cgacttcctt
    32761 ttttctataa gttaaattct attttacatg aaaagatata aaaactacaa taagatgtca
    32821 gaaaataata aaaaggaaca aaacgatgct attgatatga cacaaatcat aaatagctgc
    32881 tttgttcctt ttttaattta tatatttaaa atacacatat tcaagagctc gagatataag
    32941 tcaatgtact aggcacacaa tttaatattg acagtaatta accgaacgaa aatgcgcccc
    33001 ggggccccaa cacagagaat ttcgaaaaga taaagaaata cgttttcttt agatattagt
    33061 atttcttatg aatgagtttc acgcatgtat tcttctttct atatgcatat tagctatgac
    33121 taacgataaa gaaccactat ataataaatc atagtggttc tttatcattt ctgtcctact
    33181 cacatcttat tctttatcag ataatgcatt tttattcttt tttaaatctt cttcagtgac
    33241 gatacgtaaa ttattatttg gtgctgcgcc accttcatca tcaaatttac ctttttcaat
    33301 actttcgtca gtcttattgt catattcggt aaattttgat ttttcttctt cgaaaaatgc
    33361 ttttggatta ttttttaatc tattagcata ttctttcgga tttgttttta cttctttaat
    33421 tgtttcatta gcaattgttc ctaattgcgt cgctttatcc ttagcattat ctttatagct
    33481 ttgaggatct tgtttatatt tattatattc tgctttcagc ttgtcacgac tatctttacg
    33541 tgtaacaagt acagctgcta cagcgccacc tatacctaaa atcgctttaa ataaattacc
    33601 ttttgccata tcaatcgtct cccttttatt tataatttaa tttgtcaaaa tcattttcag
    33661 ttaataaacg atattctcct gaatctaaat tgctgtccaa ttctaaatca gcaattttga
    33721 tacgtcttaa atgtaatacc tcattttgaa tgctatgaaa cattcgttta acttgatgat
    33781 attttccttc ataaattgtt acgtgtgacg tttgattatc aatataagtt aatattgcag
    33841 gcttaacctt gccatcagtc agtgttacac cctctttaaa agcttgaatg tcgtcttcag
    33901 tgataggatt tgctgaaata acttcatatt ttttagaaac atgtttgttt ggactcatta
    33961 attcatgatt aaaatcacca tcattcgtta tcaataaaag cccttctgta tctttatcaa
    34021 gacgaccaac cggaaaaata tttagatgtt ggtattcagg tattaaatca ataacggttt
    34081 ttgaatgatg atcttcagtt gctgatatat aaccttttgg cttatttaac ataatataga
    34141 cattttcaat gtattctatt aattctccac gaactgttat cttatcgttt tctggttcta
    34201 tatgtgtttt tggtgattta attacttgtt cgttgacatt tacaaggcct tttttaagta
    34261 actgtttgac ctcattgcgt gtaccgacgc ccatatttgc taaaaattta tctattctca
    34321 tcgtaaaaac ctaactctac gtcttaattt ttcaggaatt tcacctaaga attcgtccgc
    34381 aagacgcgtt ttaattgtga ttgtaccgta aattagaata cctactgtaa cacctaaaat
    34441 aataatgatt aagtaaccaa gtttagtagg ttctaagaat agatttgcaa ggaaaaatac
    34501 taattctaca cctagcatca taataaatga atacaagaat atttttgcaa aatgaatcca
    34561 actatagctg aatttaaact tcgcatattt tttaagaata tagaaattac atccaattgc
    34621 aaataataat gcgatactag tacttaaaat tgcaccaggt gtatggaata acataattaa
    34681 tggatagttt aacgctaact tgataactac agaagctaaa ataacataaa ctgttaattt
    34741 ctgtttatct ataccttgta acattgatgc cgttacactt aatagtgaaa ttagtattgc
    34801 tacaggcgca taatagaata ataagcgact accatcatgg ttagggtcat gacctaaaac
    34861 aattggatcg taaccataga aaactgtgaa taatggttgt gccaaggcca taattccaat
    34921 actagctgga acagttataa acattaatac accaatagat gttctaattt gatgatgcat
    34981 ttcatgtaag cgaccttctg caaatgtttt tgtaatataa ggaattaaac tcactgcaaa
    35041 accagcactt aatgatgtcg gaatcattac aattttatta gttgacatat ttagcatatt
    35101 aaagaatata tcttgtaact gtgaaggtat accaactaaa gataaagcac cgttatgtgt
    35161 aaattgatct actaagttaa ataatggata attcaaactt acaataacga acggtatact
    35221 ataagcaata atttctttat acatcttgcc atatgacaca tctatatctg tgtaatcaga
    35281 ttcgaccata cgatcaatat tatgcttacg ctttctccag taataccaga gtgtgaatat
    35341 accaataatc gcaccaactg ctgctgcaaa agtagcaata ccattggcta ataaaataga
    35401 gccatcaaag acatttagta ctaaataact tccgattaat atgaaaatca cgcgtgcaat
    35461 ttgctcagtt acttctgaca ctgctgttgg ccccatagat ttataacctt ggaatatccc
    35521 tctccatgtc gctaatacag gaataaagat aacaaccata ctaatgattc ttataatcca
    35581 agtaatatca tcgactgacc aaccgttttt atcatgaatg tttctagcta atgttaattc
    35641 agaaatataa ggtgctaaga aatacagtac caagaaacct aaaacaccgg taatactcat
    35701 tacaataaaa ctcgatttat aaaatttctg acttacttta tatgccccaa tagcattata
    35761 tttcgcaaca tatttcgaag ctgctaatgg tacacctgct gtcgcaactg caattgcaat
    35821 attatatggt gcataagcgt atgtgaacgg cgccatattt tcttgtccac caattaaata
    35881 gttgaatgga atgataaaaa gtacgcccaa taccttggta attaatatac taatggtaat
    35941 taaaaaggtt ccacgcacca tttctttact ttcactcatt acgaatctcc ctatctcatg
    36001 tttattaaag ttttgtaaac taaaagctat ttctctgtaa aatcattttt cattattatg
    36061 aatatatcac aaaactttat ttcattgtcg tatattcaat gaattatcat aacaaaatta
    36121 tcaacgcatt gtcattgaat actcgatttt gattagaata ttacgaaatt tcatataaac
    36181 attatactac tatttgagat gaacatcgca taacagtaga aaaatcattc ttatcataca
    36241 catacatctt cattttttat gaagttcaca ttataaatat attcaacata attgtcatct
    36301 cataacacaa gagatatagc aaagtttaaa aaagtactat aaaatagcaa ttgaatgtcc
    36361 agtaacaaat ttggaggaag cgtatatgta tcaaacaatt attatcggag gcggacctag
    36421 cggcttaatg gcggcagtag ctgcaagcga acaaagtagc agtgtgttac tcattgaaaa
    36481 aaagaaaggt ctaggtcgta aactcaaaat atctggtggc ggtagatgta acgtaactaa
    36541 tcgattacca tatgctgaaa ttattaagaa cattcctgga aatgggaaat ttttatatag
    36601 tcccttttca atttttgata atgaatccat catagatttt tttgagtcta ggggtgttaa
    36661 attaaaagaa gaagatcacg ggcgtatgtt tccagtttcc aacaaagcac aagacgtggt
    36721 tgatacatta gtgacaacta tcgaacgcca acatgtaacg attaaagaag aagaagctgt
    36781 tagtagaatc gaagttaata cagaccaaac tttcactgta catactcaaa ataatagtta
    36841 tgaaagccat tcgctagtga ttgctacagg tggtacaagt gtccctcaaa ctggttcaac
    36901 tggtgatggt tataagttcg cacaagattt aggtcatacc attactgagt tattcccgac
    36961 cgaagttcca attacatcag ctgaaccttt catcaaatcc aatcgtctaa aaggtttaag
    37021 tttaaaagat gttgaattgt cagtacttaa gaaaaatggt aaaaaacgca tcagtcatca
    37081 aatggatatg ttatttactc attttggtat cagtggtcca gctgcattaa gatgtagtca
    37141 gtttgtttat aaagaacaaa aaaatcaaaa gacacagcac atttctatgg caatcgatgc
    37201 atttcctgaa ttaaaccatg aacaattaaa acaacacatc acatcattat tatcggacac
    37261 accagataaa atcattaaaa acagtttgca tggtctaatt gaagagcgct acttactgtt
    37321 catgctggaa caagctggaa tcgatgaaaa taccacatca catcacttat caaatcaaca
    37381 attgaacgac ttagtaaata tgtttaaagg gtttgtattt aaggtaaacg ggacattacc
    37441 tatagataag gcatttgtca caggtggtgg tgtgtcactt aaagaaattc aacctaaaac
    37501 aatgatgtct aaattagttc cgggattatt tttatgtggt gaagtattag atatacatgg
    37561 ttatactggt ggttataata ttacaagtgc actcgtaaca ggacatgtcg ctggattata
    37621 tgccggtcat tactcacata catcaatgga ataatagtat aaaatttggt tcgattctct
    37681 ttagtagatc aactttttca ttcaattaaa aatgacctta atataactga gtcactaaaa
    37741 agtgtcgtta tattaaggtc atttcgttaa ttatgattct ttttcgtttt tagtacgtct
    37801 tctagctaac aaagccgcac ctgtaatcag tgcaaattct ttcaatggta aatccattcc
    37861 ttcagaacct gtatttggaa gttctttttc aactttgcgc gattcatgtg tctcttcttt
    37921 tttaataggc gtacaaactt ttggagctgg ctgaatttct tttggtgata ctttcgtcgc
    37981 ttcagctggt aatttaattg ctaaaatttc atcaacaatg aattgcgtgt gttgtttgat
    38041 gtcatttaat gtcgcatctt catcaatcat tctattgcca tctgcaacat attgatcaat
    38101 taatactttt actttagcta attgttctgg tgttgcgatc gctttgaatt tcgcatatgt
    38161 ttgttgagca atgttatcaa ttcgcagtaa gctattttct ttttcagtaa ttactgcttc
    38221 tatatcgctt aatgcaacat taaatcgttt taaaactgca tcaacatcag cattagtgcg
    38281 tgctgttttt aattcttcat ccatttgtaa ttttaaagca gttatagctt ttaatgcatc
    38341 agccttatta cgattactta cttttcgata attttgcact aaagcagtga cgcgtgcaag
    38401 atcatcatta atcgtttttt cagcatctgg ctttttaata ggatgtacat ctaaatcatg
    38461 tattgtttgt agatttaatg atgctgtttt atcaacttgt gcattgctac gatcttgatc
    38521 aatttgtcca atagcagtgt cataaatatt ttgtaactgt gctaatatac tatttctttc
    38581 ttctaccgtt gcttgaatat tcgcttcaat tgcttgtttt ttatcgttga ataatgttgt
    38641 caattgttct cgagcagacg cctttctgtt aataacaggt tcgatttcac gaatttcgtt
    38701 tttctcatca tgcaataaat atgccacatc agcattagtc actgcactag caatttgttg
    38761 tttagcttta attaactctt tttcaacttg tgctattgca atattttgtt cttcatctgt
    38821 cgcttcgtta tttgctttaa ttaaattaat tttatttgta gcgatatttt gaatttgttg
    38881 taatgctgtt gctttaactg ttgtcgctgg tttaattttt gaaataatat tttgagcatc
    38941 tatactatct tgattaactt gggcagtctt atctgcatga ttgatctgat caatagcctg
    39001 attaagtgct tgttctacta aatgtttagc agctagtctt tcttcttcag ttgataaatc
    39061 gctttgatcg attagtgcat tttgagcttc ggcttttaca ccaacagatt gacgcgctgc
    39121 tggtttaact tgaactttag gtaaaatcac tttgatgttg tcgttgccat cagtctcagt
    39181 tcgatccact tctgcattcg ttttgttttg tgcaatgtca tttttaattg tatttacaat
    39241 tttatttaaa gtatcaatag caacatctct ttcatcttga gtagtatcca acgtatttcg
    39301 gattgcatcg agttgatttt tattattttc ttcaatgcta tcaagcgcag ctcgtttacg
    39361 tcttacttta ggttttattt gctcaattgc cttgattgtt tgatttctaa catcagtaac
    39421 agcagcatct tgatttgtat tttctatttc ttgttgcgct tgtttgagtg tgtcgctaat
    39481 taattgattc gcttcatcta attcatcaac tgttgcatgt ggtgtatctt ttattgattc
    39541 tacttgattt tctgcagttg cttttattgc ttgttgtgct tcaggcttaa ttacaatatg
    39601 aggttgtaca ccttttagtg tagcaatgcc atttgtttca acacgtttca catcattatt
    39661 cgttactgct tgattgatgt tttgtaatgc aagtttttca ttattcgcta attgatttaa
    39721 agcaacttgt ttttcttcat cagtcgcatg ttcagcttgc tctatttctt gctttttagc
    39781 ctcatattgt tgctttactg catctctagc agctgctcta acaatatgtt caggcgctac
    39841 taaagcaatg ctatcaagcg cttgacttgt tgtatcatca acttgttgat ttgttctatt
    39901 attcgtaata tctgtcatgg cttgatttac aaattcattg attttatcta gtgctacttg
    39961 tctttcttct gctgttgctt ctttatcctg attaatctta gcacgtaatt cattcgcttt
    40021 ttgattgatt ttttcacgtg cagctggttt aacttttgtt tcaggttgaa taattttaat
    40081 cgctgataca ccatttgttg ctgcttgatt cacctgacta ttcgtttgag cttggtcaat
    40141 agctgcaagt gctttttctt tttctttagc taatgcttgt gaagcaactt ctttctcatt
    40201 atctgttgaa tcaagactat tatcaatttg ctgttgcttt tctttaacag ctttttcaat
    40261 atctgcaatt gcctttggtt taattactac ttcagcttca acattatcta tagcatttac
    40321 cgcttgattt gtagttgtgt ctacctgatc atttgtttgg ttttgattaa tttgattaat
    40381 tgcttgatct ttaagttgat tgatttgatt aacagcagcc tgcttttctt cgtcagttgc
    40441 attaggtgtt tgtttaaccg cttcaatacg cttcgccact tcagcagtga ttttatctcg
    40501 cgctgcttgt ttttttacta catcaacttg aacagcatcg atattattct ctgctactgt
    40561 cgcagcttgg tctacttctg catttgtgtt agcttgttta atactttcaa tagcttgttg
    40621 tctgtcttga tttaaagtat tgatcgcagc atttttctca tcattcgttg catctggtgt
    40681 agcattgatt tcagctaatt tagcattata atgctgattg atttgtgcta atgctgcagg
    40741 ttttttaaca atatttggct gaatcgcatt aattgctttt gtacctaatt gttgcgcttg
    40801 atctacttcc gcatttgtat cagcttgatt tatattatta attgccgttg ctaactcttg
    40861 atccacttga tttaaagcca cttgcttttc ttcagttgtt gcatttgtgt tttgattaat
    40921 ttcttgcttt ttagcagttg ctaaatcatt taatacacct gtagcagttt gtttcttcgt
    40981 tacatgcggt tgaactgcgc cgatttgatt gactgcatcg tctctaatac tattgaccat
    41041 cgcagtagta gacgtcacac caatatcagt taatgctcta tttttaagtg tattgacacg
    41101 atttatcgct tcttgtttct cttctcgagt cgcgccaggt gtagcattga tatttgttat
    41161 cgcctctcga gctttatcat ttacagcatt gcgagcatcc gttttaactt gtgttgccgg
    41221 ttgaatcaca actatatttt gtgtgccctg atcttttgct tgtgcaactt cttgattcgt
    41281 atctgctgca ttaatatttt gcttcgctgt ggctacagct tgatcaagta attgttgtgc
    41341 tgcttgttgt tcttcgagcg tcgcatcatt attattaaat atcgtattat gttgcgtttc
    41401 cgcactttta tcgatggcat tttttgcatc tgtttttact tttgtagctg gtgtaattgc
    41461 ttgtattcct tgaatcgcat ttgtctttac ttgttcaaca tcagcattgg tattagcgtt
    41521 taaaatgttt gtgtttgctg cagttacagc agcattcact ttgtcaattg ctgcttgtct
    41581 ttcttcttga gtcgcatcag gattagcatt gatttctgcg atatgttgtt gtgcatcatg
    41641 tgatacagca tcccttgcag cttgcttaac aacagttaca ggagcaattg gattaatggc
    41701 atttagacca tctcctttgg cgttatcaac atcagcattt gttgttgctt gattgatttg
    41761 ttctaaagca tggttggttg cttgagttaa ttcgttcaat gctgcatttt tctcttcctg
    41821 agttgcttct ctattactat ttatttgttg tcttttcgtt gctgttgctt ggttaattgc
    41881 atctcttgca gcttgtttat gtgtcacttg aggaacaact gctccaatag tattgatgcc
    41941 attattttta gctatttcaa cgtcagcatt tgtagtagca ttcgtaacat tatcaatagc
    42001 atctgtttca tccgtagcta attgatttag tgcatcttga atctcgtctt cagtagcatc
    42061 tggtgttgca ttgataattt ccctttgttt cgttgcttta tcacgtattg cttttttagc
    42121 atttggttta acaaccggtg ttgcagtatc cccacttaag gtctgtatac cttgatcttt
    42181 gattctagta acgccatcat cagtcgtttg gtcaccaata ttaccaatta tttcattttt
    42241 atgttcctcg ataacttgta ttgctgcttg tttttcttca tctgtcaatt catcattttg
    42301 attaactaaa tcttccattt ggtcaacttt tttattaact gcattttcag catcaacact
    42361 tcgaattaac gtatgttgca tttgattagt taatgaatca atatttgctt gagaaactct
    42421 tttatttaat ggtacattgt tacgattttc atctaaaatc gtttgtgcac gtcttttaag
    42481 atcattaaag atatctaatg atgcaaatgt ataatcagct tgttgaatgc gtctatcaac
    42541 ctcggcttgt aatgcatctt tattcatgat gatatcgatt gtatatggat ttgtacttac
    42601 agtatgactt tcagcaggtg aattaataaa atcttgtgta tatgttttat atgttaatgt
    42661 atcattaaat gttactgttc ttggtgtcgg tacattatta acacgcaact tatactttaa
    42721 atccaatatt ttatcaggca ttaatcgtgc cggcgagtta cctgaacctc caccagtact
    42781 tttaattgtt atcactcgat tcgccgcatc atacgtcaca ttaaaatcat tcatatcaac
    42841 acctgaatta ctgcttggaa aatctttagt caatgagtta ttaacatatt ctaccccttc
    42901 aggtaattga actttatata caaaatcatc tgtattaaat gaagcaccga agttaccatt
    42961 attctttaat gaagttgtga ctgtaaattc tttattatta gtagctgtgg gttccattgt
    43021 tcgtctttca acatagacat gcgaaccaga atgtagacca attgagtcaa caaagtcata
    43081 gtatttataa ccgtctctta gttgataaat gccacgcgca tctgttattg catcattttt
    43141 aggtacaaat tgaattttta agtgactaac attttcaggc actttaaaca aacgccaaat
    43201 cggaccataa gctactgatt tttctgcaat aacagtatca ttatcagcat ttttaattat
    43261 taaatttgtc acaccttgat agttttttgt agtcatcgta ttaaattcga aaattaattc
    43321 agaatttgga tttactgtta aagatttttc aattccatta aaatcaccat gatcatttgt
    43381 atcatttccc ttaatacgac ctaatgcaat tacatttcct tgtgcttgat agttcttagc
    43441 atctcctgaa tcaaacatac ttgttctaac catcgcatga ctaaacacac ctactttacc
    43501 accattgata agtgtaaagc ctggtaaatt atcaacaact gttactgatg gtacagaacg
    43561 gttggtactt ggtctaatac cattgtcatc aaaagacagc acttcgttag gtgcattttg
    43621 tcctgcatta ttggcattag gatcagttgt cggcgtgtat ggcgctgtaa ttgctactgg
    43681 tgcaccaccg tttcctgccg ctgcagccgc tggatctgct ggagttgcat taggatctgc
    43741 cggtgccgca cgtctacttc tctttttcgg tctattagat gcttgttcag caattgcaac
    43801 tagctctggt ttatctgaag aatgacgaac atcttcttga atttccttta aagttagatg
    43861 tcctcctgaa ccattttcat ttgttttatt aggtacattt aatgtggtat tattcgacac
    43921 tacatcctta ttattagcgt ttgacactgt ctcagttgct gttgtattgc catctgtatg
    43981 attattgttt tgtgctgaag gcgtacttga ttgcactgat gttggcgtag cttgatttgc
    44041 tatactacca ttattatgat taaccaatgc ttgattcgtt gattgattag ttgttgcaga
    44101 ttgattaggt gtattctgag cactatttgc taaacctcta ttattagcaa catttgtatc
    44161 ttgtgaattt acaggtgtgg cttgattagt atcgctttgt acattattat ccgtagttaa
    44221 ggcttgtgca ccatttgggt ttgaaagtaa taaaactgtt ccgattaaag tagagaatat
    44281 gcctacttta tacttcctaa tactatattt atttttcttt aacaaattca tttcattttc
    44341 ctcctggttg tctgttctct gctgtgttgt ttagaattat gctaaaaata tacgctctct
    44401 catattatgt ttatagctat attattttgt acaatatttt aagttcactc aattttatca
    44461 tcatcatttt ataaaataaa gttttatttt attacaattt agtttccgtt ttgtaattaa
    44521 aatcttaata aaacataaca agaacgcttt agattgtttt gtaacagaaa gtaattcata
    44581 ccaaaaaaca ccaagcaacc gaaacgttac ttggtgtcat tacaaatgta atattatttt
    44641 aaattatgtc actactttaa atacttttta tttccaaacc ttcatcgccc catgcgtgca
    44701 tgccgccttc gacatttacg gcatcaatgc catttgcctc taaatattct acaactttag
    44761 cgcttcgaac tccaccagca catacaatat aatatatttc atttttatta aatgaattta
    44821 aattatccgg aatggtatcc attggaatca actttgcatt aggaatatat cccattgctg
    44881 tttcttcgtc agtacgaaca tcaacaattt gaactggttt agattcaaaa agtttgtttt
    44941 ttaattcatc tgtagtaatt gacttcattt caaagtcctc cttaaaacat tatttagcta
    45001 caatattgac taatttttga ggaacagcga tgactttcat gatgtcttta ccttcaatac
    45061 tcgctttaac attgtcatta gataaggcaa tttcttgcat ttcttctttt gatgtatctt
    45121 tagcaatttt aattttagct ctcaatttac catttacttg aacaacgatt tctacttcat
    45181 catctacaag tagtgcttcg tcataagttg gccaaggttg gtacgtaata gactcttcat
    45241 gtcctaattt tgaccataat tcttcaccga tatgtggtgc aataggtgct aacattttaa
    45301 cgaagccttc aatgtaaggt ttataaactt catcaacttt ataacactca ttaataaata
    45361 ccattaattg actaatagca gtattaaatc ctaatgtttc aaagtcttct gttacctttt
    45421 taacagtttg gttataaact ttatctaaag atttattatt tgtagttaca atttttgaac
    45481 tcaatgttcc atcttcattt accattaaac gccatacgcg atctaagaat cgacgagacc
    45541 catctaatcc tttttcactc catgcaattg cagcatctaa aggtcccata aacatttcgt
    45601 aaagacgtaa agtatctgca ccatgagact gtactatatc atcaggattg attacatttc
    45661 ctttagattt actcatcttc tcattacctt ctcctaaaat cataccttgg ttaaataatt
    45721 tttggaaagg ttctttagta ggtacgatac ccaaatcata aaggacttta tgccaaaatc
    45781 ttgcatataa taagtgaaga accgcatgtt ctactccacc gatatataaa tcaacaggta
    45841 accaatgttt taatttttca ggatctgcta acatattttc atttttagga tcgatgtaac
    45901 gtaaataata ccaacaacta cctgcccatt gtggcattgt atttgtttca cgacgtcctt
    45961 tcatacctgt tttttcatct acaacattta caaatgaatc aatattagct agtggagact
    46021 caccagtccc tgatggcttg atttcatctg tttcaggtaa caacaatggt agctcttctt
    46081 caggaacagt tgtcattgtt ccatcttccc aatgaatgac aggaattggt tcgccccaat
    46141 aacgctgacg actgaataac caatctctta atttgtaatt aactttcttt tcgccagcac
    46201 ctttttgctc taataattga atagctttag taattgccgc ttcattttct aaaccatcaa
    46261 gttcaccaga attaatatgt ttaccttcac cagtgtatgc tgcttcttca acatttccac
    46321 cttcgatgac ttcaatgatt ggcaaatcaa actttttagc aaattcataa tctctgtcat
    46381 catgcgctgg tactgccata attgctccag taccatatgt tgataataca taatcagcaa
    46441 tccaaatttg tactttttca ccagataaag gattaattgc atatgcacca gtaaacacac
    46501 ctgatttatc ttttgctaaa tctgtacgtt ctaaatctga ctttttagaa gcttctgttt
    46561 gataagcttt tactttttct ttatattcat cagttgtaat tgaattaact aatgcatgtt
    46621 caggacttaa gactaagaat gatgcaccat agatagtgtc tggtctagtc gtaaatactt
    46681 ctacttttcc ttccgtatta tctacatcaa atgaaacttt ggccccttca gaacgtccaa
    46741 tccaattgcg ctgcatatct tttaaagact caggccaatc taaatcatct aaatctgcta
    46801 ataattgatc tgcatattct gtgattttaa gtacccattg tttcatcggc ttacgataaa
    46861 ctggatgtcc accacgttca gagacaccat caatcacttc ttcgttagat aaaacagtgc
    46921 ctaatgctgg acaccagtta actgcaactt catcaacgta tgctaaacct ttgttatata
    46981 actgtatgaa aatccactgt gtccatttat agtattctgg atctgttgta ttaacttcac
    47041 gatcccaatc ataactgaac cctaattctt taatttgtcg tttaaaagtt tggatatttt
    47101 tctttgtaaa ttcacgtggg tcgttgccag tgtctaaagc atattgctct gctggtaatc
    47161 cgaatgcatc ccaccccatc ggatgtaata cattataacc ttgcatcctt ttatatcttg
    47221 aaatgatatc tgttgctgta tagccctcag gatgtccaac atgtaaacca gcacctgatg
    47281 gatatggaaa catgtctaaa gcataaaatt tcttttgacc taagttatca tttgttttaa
    47341 atgttttatt ttcgtcccaa tagtcttgcc atttcttttc aatttgattg tggttgtaat
    47401 tcaacacatt tcctcctatt caataaaaaa gacacctcta actattctat ttacataggg
    47461 acgacatttg ccgcgttacc accctatttc acaaaaattg tgcactcatt ttaatagtaa
    47521 gagatgtcat tcattcaatt taaaattaat acgatttaca tttagtcctt aacactagct
    47581 ctcagcatca ctagctttct gtagaaaagc tccaaacgaa attaaattat acaaattaat
    47641 attatgttat aacgacattt atttcaagtc tataacgtta attctattta ctcattatgc
    47701 atctattttt ttaggttgcg tattattctc cttgaaaacc attaataata ttaatgcaaa
    47761 tacaagtagt agcatcatac cgataaacat catgcgcata ttaaacgcat caactaatac
    47821 accaccaaga aatggaccaa atgcttttcc tactgtagca gctgaattca caaaaccttg
    47881 gtactgtcct tgcttaccat ctggcgctaa ctgattggct atagttggaa ctgctggcca
    47941 tacaaacatt tctccaaaag ttaaaataat cataccgaca acaaatattg taaagttttc
    48001 ggcaaaactc gtgacaaaga acgacaacat aaaaatgatg atgccgacaa acatttgctt
    48061 ctttaagttt ccttttaaca gatagagaac cggtttaatt aatggttgtg ctactaaaat
    48121 cattattccg ttaattgtcc ataaaacact atattgtgcc attgaaatat taatagattg
    48181 tgtaaatgat gcgattgtag actcccattg aatatacgca acccaacaaa ttgcaaacat
    48241 tgcacaaatt agtactaatg aaataaatct tgctttattc tttttaccag taatatctaa
    48301 atgagttgga tatttaactt tcgcattaat ttcaatatta aattgcgtta ccgcgacaag
    48361 cgcaaacaca acatacataa taagattggc taaaaagata tagttaaagc taaattctgc
    48421 gacaaagccg cccattgcag caccgacagc cacaccaata ttttgcgcta agtatatcgc
    48481 attaaacgtt tgtcttccgc cattcggcca cactgctcca gccatagcgt atatcgcagg
    48541 aataatcatt ccgccaccaa agcctaacat tacaagccat acagcatacc aaggccaccc
    48601 gtgaaagaaa ttaagtagcg ttgtactaca aagacaagtg aaagttccaa ttaaaatcgt
    48661 cttgtatcca cctaatttat caaatagtga accacctaat aagtttccaa taaccatgcc
    48721 aaatgaattt atcattagca ctaaaccagc aacagttaaa ctttttccaa gttcttgttt
    48781 catataaatt gtatttaaag gccacaaaaa actggaacca gtaatattta acgccatgcc
    48841 aattactagc caccagactg atttaggtat attcatattt catagttcct ctctcttttt
    48901 tgtcaaacta taataaacac tataacatta aaatatgtta aaatctgtac ttagaactct
    48961 ttttttatag aaaggaaaat gacatatggg caatcatttc caatacgctt ttgaaaacaa
    49021 acgttatcac acatggaatt accatttaaa aaataaattt ggacaaaaaa tatttaaagt
    49081 tgcattggat ggcgggtttg actgtcctaa ccgcgatggc actgtagcac atggtggatg
    49141 tacattttgt tctgctgcag gtagcgggga ctttgcaggt aatcgtgcag attcaatcgc
    49201 agtacaattt aaagaaatta aggaaaagat gcatgagaaa tggcacgaag gaaaatatat
    49261 tgcttatttt caggcattta caaatacaca tgcaccagtt gaagtattaa aagaaaaatt
    49321 cgaacctgta cttaaagaac cgggtgttgt aggattatct attggtacgc gtcctgactg
    49381 tctaccagac gatgttgtcg aatatttagc agatttgaat caacgaacat acttatgggt
    49441 tgaattagga ctacaaacaa tccatcagtc aacatctgat ttaatcaatc gtgcccatga
    49501 tatgaaaact tattatgatg gtgtggcaaa attacgtaag cataatatca atgtatgtac
    49561 acacatcatt aatggcttac ctggcgaaga ctatgacatg atgatggcta ctgccaaaga
    49621 agttgcacaa atggatgtac aaggtattaa aattcattta cttcatttgt taaaaggtac
    49681 accgatggta aaacaatacg ataaaggttt attaactttt atgactcaag aagagtacac
    49741 aaacctagtt gtggaccaat tagaagtgat tccccctgaa atgatcgttc accgaattac
    49801 cggtgatggt ccaatagata tcatggtagg tccaatgtgg agtgttaata aatgggaagt
    49861 attaaatggc atcgatgctg aattagcacg tagaaattct tatcaaggct tgcgttacaa
    49921 gtctaaggtg aagcaatgaa attagaacgt atactccctt tttcaaaaac acttattaaa
    49981 caacatataa caccagaaag tattgttgtg gacgcaactt gcggtaacgg caatgacact
    50041 ttatttttag ccgaacaagt accagaagga catgtttatg gtttcgacat tcaagattta
    50101 gctttggaaa atacacgtga taaagttaag gatttcaatc atgtttcttt aataaaagat
    50161 ggacatgaaa atattgaaca tcatataaat gatgcacata aaggtcatat tgatgcagcc
    50221 atctttaacc taggttattt gcctaaaggt gataaatcta tcgtgacaaa gcctgacacg
    50281 acaatccaag ctattaattc attgctatca ttaatgtcaa ttgaaggtat tattgtactt
    50341 gttatatatc atggtcatag cgaaggacaa attgagaagc atgcattgct tgattacttg
    50401 agtactttgg atcaaaagca tgcgcaagtt ttgcaatatc aatttttaaa ccaacgtaat
    50461 catgctccat tcatttgtgc catagaaaaa atttcttaag catttgctgc gctatactat
    50521 ttataattta ggattgagta gtcaacattt gaaaaattaa taccaacaac aacaaaaaga
    50581 ggttttcaac ttaatgaaaa cctcttttta tgctattaaa cttacacagc aataattgcg
    50641 tttaaactat tttgcattgc tgttgctcta cttgcaatgg catcactgat gaaattcaac
    50701 aactctactt tctcttgttg taacttttca ttgaaatgaa taataactgt tctttcatcg
    50761 tcaacaggac gctctttgta aatccattct aattcaacta aattattata cgttctcgta
    50821 cgcttatacg gtttaacttc aacaaatctg tccatttctt taagcgtcat agaacctttt
    50881 tgccataaag ttagtaaaat taaaatttct tctctagaca ttttgtattc gctttcaatc
    50941 tcgctgaaaa ttgagttaat gtcacccaaa agtgtttcta attgcaaaat cccaaataca
    51001 gtgtcgttat ttactttttt catgctaaac atc
//
LOCUS       DAPDIM010000012        49027 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000012 DAPDIM010000000
VERSION     DAPDIM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 49027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49027
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.012"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            93..866
                     /gene="lpl1"
                     /locus_tag="RFE25_000752"
     CDS             93..866
                     /gene="lpl1"
                     /locus_tag="RFE25_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein Lpl1"
                     /protein_id="HDU2815847.1"
                     /translation="MRYLKRLSWYISILILIVVIAGCGKGNETKEGSKEEQIKKSFAK
                     TLDMYPIKNLEDLYDKEGYRDSEFKKSDKGTWTIYTDFAKSNKPGELDDEGMVLNLDR
                     NTRTAKGHYFVTTFYRNGKLPDEKNYKIEMKNNKIILLDEVKDDKLKQKIENFKFFGQ
                     YANLKELRKYNNGDVSINENVPSYDVEYKMSNKDEIVKELRSRYNISTEKSPILKMHI
                     DGDLKGSSVGYRKLEIDFSKRENSKLSVIEFLSYKPAKK"
     gene            897..1691
                     /locus_tag="RFE25_000753"
     CDS             897..1691
                     /locus_tag="RFE25_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815848.1"
                     /translation="MGYLKKLALFISVIILGIFIIGCDSSSDTAEKAKEDSKEEQIKK
                     SFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWTLLTSFSKSNKPGEIDDEGMVL
                     YLNRNTKKATGYYFVNKIYDDISKNQNEKKYRVELKNNKIILLDNVEDEKLKQKIENF
                     KFFSQYADFKDLKNYQDGSITTNENVPRYEAEYKLNNSDTNVKKLRDIYPITTKKAPI
                     LKLHIDGDIKGSSVGYKKIEYKFSKVKDQETTLRDYLNFGPSDEDS"
     gene            1739..2524
                     /locus_tag="RFE25_000754"
     CDS             1739..2524
                     /locus_tag="RFE25_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815849.1"
                     /translation="MGYSKRFALYISVMILIFAIAGCGKSDETKEGSKEEQIKKSFAK
                     TLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWVISSVMVKQPKGEIMKSRGMYLFLNR
                     NTRTAKGYFIVDETSNDTLKKTEDKEKRYPVKMVNNKIVPIDPINDKGVKKEIENFKF
                     FSQYGDFKELKNYKNGEVSYNSEAPIYSAKYQLKNNDYNVKQLRKRYDISTEKAPKLL
                     LKGTGDLKGSSIGHKDIEFTFVENQEENIFFTDSLEFTSSENY"
     gene            2570..3331
                     /locus_tag="RFE25_000755"
     CDS             2570..3331
                     /locus_tag="RFE25_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815850.1"
                     /translation="MCVVYRTSVLILLASGCSGVFDTPEDSKETQIKKSFAKTLDMYP
                     IKNLEDLYDKEGYRDGEFKKGDKGTWVVRSEMIIQPKGKSLTSRGMILYMNRNTRTTT
                     GYFSIEEIDSRKSLDERETEKKYPVKMINNKIIPTEEIKDEKLKKEIENFKFFVQYGS
                     FKGIENYENGDISYNSEAPIYSAKYKLKNDDYNVKELRKRYNIPTEKAPKLLLKGSGD
                     LKGSSVGYKEIEFIFIENKKENIYFSDGLNLIPSD"
     gene            3392..4177
                     /locus_tag="RFE25_000756"
     CDS             3392..4177
                     /locus_tag="RFE25_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815851.1"
                     /translation="MRDSKRVVLYISIMVLSIFIIGCGKGNEIKEDAKEEQIKKSFAK
                     TLDMYPIKNLEDLYDKEGYRDGEFKKGDKGMWTIYTDFAKSNRPGVLDNEGMVLNLDR
                     NTRTAKGYYFVDTIYDNHENSYSKNYRVEMKNNKIILLDKVEDQKLKERIENFKFFGQ
                     YADFKSLKSYNHGDVSINSNVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPILKMHI
                     DGDLKGSSVGYKKLEIDFSKEENSELSIVDSLNFQPAKNKDDE"
     gene            4196..4978
                     /locus_tag="RFE25_000757"
     CDS             4196..4978
                     /locus_tag="RFE25_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815852.1"
                     /translation="MGYSKRFALYISILILIVMVAGCGKSDETKEDSKEEQIKKSFAK
                     TLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWVLYSAIVSQPKGESLKSRGMILKLDR
                     NKRTAKGSYIIRELKEDKNHDVQKNEKKYPVKLVNNRIVLVKDVKDKKLKNEIESFEL
                     FSQYGNFNHFDRNEITNISYNPNAPNYSAEYKMKKNDRNIQQLKKRFNLKTSKTPKLL
                     FKGSGDIKGSSVGYKEIEIIFSRSKEEAFIMLTALSSFQVTK"
     gene            5038..5829
                     /locus_tag="RFE25_000758"
     CDS             5038..5829
                     /locus_tag="RFE25_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001802015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815853.1"
                     /translation="MGYLKRLVLYIVIMVMSVFIIGCDKSSDTAENPKEGSKEAQIKK
                     SFSKTLDMYPIKNLENLYDKEGYRDGEFKKGDKGTWTISTDFAKSNKQGEMNSEGMVL
                     HFNRNTRTATGYYTVRTTYDEVDKLAREKKYRVEFKNNKIVLLDKVEDENLKQKIENF
                     KFFGQYADFKDLKNYKNGRISSNENVPYYEAEYKRNNSDGNVKKLREKYPITTKQSPI
                     LKLHIDGDIKGSSVGYKQIEYTFSKEKDDETFMSDFLNFGPSHSK"
     gene            5881..6681
                     /locus_tag="RFE25_000759"
     CDS             5881..6681
                     /locus_tag="RFE25_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001797296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815854.1"
                     /translation="MGYFKRVVLYIIVMVVSVFIIGCNKSSDTSEKPKEDSKETQIKK
                     SFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGMWTIYTDFAKSNKQGGLSNEGMVL
                     YLDRNTRTAKGHYFVKTFYNKGKFPDRKNYKVEMKNNKIILLDKVEDINLKKRIENFK
                     FFGQYANLKELKNYSNGDVSINENVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPVL
                     KMHIDGDLKGSSVGYKKLEIDFSKGEKSDLSVIDSLNFQPAKVDEDDE"
     gene            6700..7482
                     /locus_tag="RFE25_000760"
     CDS             6700..7482
                     /locus_tag="RFE25_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815855.1"
                     /translation="MKSIKRIGLCISLLILIIFATSCGSNKITGDSKEEQIKKSFAKS
                     LDKYPTENLEEFYDKEGYRDGEFEKDDKGTWLIRSEMKIQLKGENLESRGAVIEINRN
                     TRTAKGNYIVREVVEDSDGMTHNHTKRYPVKMENNKMIPLKSIDDEKVKKEIEEFKFF
                     VQYGNFKELENYKEDEVSYNPEVPIYSAQYQLKNSDYNVEQLRKRYNIPTQKAPKLLL
                     KGSGNLKGSSVGYKNIEFTFVENKEENIYFTDSVYFNPSEDK"
     gene            7664..8476
                     /locus_tag="RFE25_000761"
     CDS             7664..8476
                     /locus_tag="RFE25_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014936986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2815856.1"
                     /translation="MEYIKKIALYMSVLLLIIFIGGCGNMKEEQKKEANTNKTDSKEE
                     KIKKSFAKTLDMYPIKNLEELYDKEGYRDGEFEKGDKGMWTIYTDFAKSNKPGELSNE
                     GMVLYLDRNTRTAKGYYFVRTFYRKDKLPDRKNYKVEMKNNKIILLDKVEDPNLKKRI
                     ENFKFFGQYANLKELKNYSNGDVSINENVPSYDVKYKMSNKDENVKQLRSRYNIPTDK
                     SPVLKMHIDGNLKGSSVGDRKLEIDFSKRENSHLSVIDSLDYQPAKVDEDER"
     gene            8466..9791
                     /locus_tag="RFE25_000762"
     CDS             8466..9791
                     /locus_tag="RFE25_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001581953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815857.1"
                     /translation="MKDKYKIDPGIIKNNTEETTAISKISYEVENANLYGADSEDITR
                     QIEYLKAKKKFPSNLEYVDSYTDSLNGVTTSAFLNKDTGKVTLGMTGTNIQGEAFKKL
                     KEGEFSRQNVTNALETVKDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFIT
                     GHSLGGRDAVVLGMSNGIPNIVVYNPAPISINSLNPNSPDGKRLLELYKNYKGNITRF
                     VAENDALTENLKKYKHYVFFGNDKVFKNGKGHEMEGFLTEEEQKAIKKELKKLQGYAE
                     ENNKSFVKNSNNAISKLASIELLRANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQL
                     IDDEINQIKKMYNEKKKEFGKNWEDAQKAGKAVGEDLSVNGVLNALDEGQVNESSMVR
                     EPEQMISAKERQLSTIGSSVSNYIMRVRLSINEIVDKDQVLASQIGGLL"
     gene            9788..10111
                     /locus_tag="RFE25_000763"
     CDS             9788..10111
                     /locus_tag="RFE25_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815858.1"
                     /translation="MMFNQINNKNELEESYESEKKRIENELHNLNELRHRTRKENERS
                     YDVFQYLKHEMNYSEDAQRKMTRNIEAYEQEINEIIRKQEWKLEEYKEDLKKSYEKQL
                     DKLSD"
     gene            10130..10444
                     /locus_tag="RFE25_000764"
     CDS             10130..10444
                     /locus_tag="RFE25_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815859.1"
                     /translation="MTLIEPDMNLRMPDISTTVETLNLISKMEAQKENIRSVIAPEHK
                     HKYKDIENGLKGEEKVLIEQMAQHCEAFKANFKGAAQGDWVKSAMSEIDSIKDDLKKI
                     NS"
     gene            complement(10733..10933)
                     /locus_tag="RFE25_000765"
     CDS             complement(10733..10933)
                     /locus_tag="RFE25_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001790020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815860.1"
                     /translation="MNMLFVILVLYVIGIAFILLSVFGSKTEGLSTKHTLYTIGSAII
                     TIAIFISIGYAIQYLTAALYGL"
     gene            11112..12314
                     /locus_tag="RFE25_000766"
     CDS             11112..12314
                     /locus_tag="RFE25_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDU2815861.1"
                     /translation="MAKIPVTVLSGYLGSGKTTLLNHILQNREGRRIAVIVNDMSEVN
                     IDKDLVADGGGLSRTDEKLVELSNGCICCTLRDDLLKEVERLVKKGGIDQIVIESTGI
                     SEPVPVAQTFSYIDDELGIDLTAICRLDTMVTVVDANRFVHDINSEDLLMDRDQSVDE
                     TDERSIADLLIDQVEFCDVLIINKIDLISEEELAKLEKVLSALQPIAKIIKTTNSEVD
                     LKEVLNTQRFDFEKASESAGWIKELESGGHASHTPETEEYGISSFVYKRRLPFHAKRF
                     NDWLESMSNNVVRSKGIVWLAQYNHVACLLSQAGSSCNIHPVTYWVASMSEAQQTQIL
                     AERQDVAAEWDPEYGDRHTQFVIIGTELDEEKLTKELDACLVNAQEIDADWQQFEDPY
                     QWQIRPAR"
     gene            complement(12973..13035)
                     /locus_tag="RFE25_000767"
     CDS             complement(12973..13035)
                     /locus_tag="RFE25_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014532416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-4"
                     /protein_id="HDU2815862.1"
                     /translation="MAIVGTIIKIIKAIIDIFAK"
     gene            complement(13099..13167)
                     /locus_tag="RFE25_000768"
     CDS             complement(13099..13167)
                     /locus_tag="RFE25_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-3"
                     /protein_id="HDU2815863.1"
                     /translation="MEFVAKLFKFFKDLLGKFLGNN"
     gene            complement(13219..13284)
                     /locus_tag="RFE25_000769"
     CDS             complement(13219..13284)
                     /locus_tag="RFE25_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-2"
                     /protein_id="HDU2815864.1"
                     /translation="MGIIAGIIKFIKGLIEKFTGK"
     gene            complement(13316..13381)
                     /locus_tag="RFE25_000770"
     CDS             complement(13316..13381)
                     /locus_tag="RFE25_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-1"
                     /protein_id="HDU2815865.1"
                     /translation="MGIIAGIIKVIKSLIEQFTGK"
     gene            13902..15386
                     /locus_tag="RFE25_000771"
     CDS             13902..15386
                     /locus_tag="RFE25_000771"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase subunit 5"
                     /protein_id="HDU2815866.1"
                     /translation="MLSFQLLFSLFVIALIIALISGLLFLAPVMPMRYIKLHLYILVM
                     PVLFAVIGFFGIHGQHVLGPFKIDRLSWLLAGFVMALGFIIQKFSMRYLLGDHHYRHY
                     FPLFTAITSFASLAWMSEDLRLMALCWGMTLLCLTLLMNVNRFWKVPRESAKLSSMTF
                     LCGWLAFVGAIVTIYIATGEWRVPQHIVHPTWSLLTNVLLVLAVMIPAAQFPFHRWLI
                     ESVTAPTPVSAIMHAGIVNAGGVILTRFAPIFDNGFALSLLLILSSISVLLGSGISLV
                     QVDYKRQLVGSTMSQMGFMLVQCALGVYSAAIIHLILHGIFKATLFLQSGSIVKRFNI
                     PKQASAKDAYGWIVMGRVLAIIVAFLFWMSSDRSAYEVLSALILAWSLLVSWNQMVAF
                     SKGRMARLVGMILIAIVTFIYVITHNYFYDVLQNITTHATTPPTVSVIISVVILIFGS
                     LLSIWVARHRYSKGFAVLYVWLVNLGEARSKAIESHPNYLKKYL"
     gene            15399..18104
                     /locus_tag="RFE25_000772"
     CDS             15399..18104
                     /locus_tag="RFE25_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbcC family protein"
                     /protein_id="HDU2815867.1"
                     /translation="MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDV
                     AKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYID
                     NIKTLKDVPASYMNHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLS
                     EQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPN
                     DPEMTIESVLTYFSIDQEDYQAYVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAI
                     RLVVEQLLVGDEFKSVTKDCESRSENWFKQTVASLCYYSDMPSDVLLQHDVNEIQTFI
                     HFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNANQP
                     HSVLLNDTQAVDENNSELNQVGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGF
                     FGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLM
                     KNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFD
                     RTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGAC
                     GGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWVYVPDT
                     LSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEW
                     GLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTIISGPALVAQWINLQ
                     YYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRL
                     LVVIQAPDYVVARLFANNEHFARKVSNHWLRLMSVNEEGRFKSWI"
     gene            18266..18628
                     /locus_tag="RFE25_000773"
     CDS             18266..18628
                     /locus_tag="RFE25_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2294 domain-containing protein"
                     /protein_id="HDU2815868.1"
                     /translation="MKRTKGEIEAEISKAITQWEKDFLGRGSLSVKSDILRDMVIISL
                     QGILTPAEYRVCSTNEGLLNIKRTRSELVESGEQDLNDIILKITGIKVMSFHSDLSTV
                     TGERIIVFKLEDNLEKHI"
     gene            complement(18857..19273)
                     /locus_tag="RFE25_000774"
     CDS             complement(18857..19273)
                     /locus_tag="RFE25_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815869.1"
                     /translation="MLSIISMCHKFHFTDNIKIIKFILLCILQIKHCIIEITIFCYFQ
                     FSTIYIYYTEGVRRINRVIFVYIALIITLVRFFTPIHPSFSNLIYWIFVLYFIPIILC
                     VIGFKAEKLIATMVIIPNFLGILYRLYAYVTHILFM"
     gene            19311..19985
                     /locus_tag="RFE25_000775"
     CDS             19311..19985
                     /locus_tag="RFE25_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDU2815870.1"
                     /translation="MIDKKLTSPKMTVPLFLIALIVFIGMFYGVVTNQEWLKNIDMGS
                     LTWFTDYFGEPQRQYVNNLFNYYMTFSAEIGDVKGVVLISIIVTIILFIKQRHLAVWF
                     VTYLVSGVIMNKLIKDTVLRPRPYNHLAVDTGFSFPSGHSNASTLLYFALMIIIISVA
                     AKTITKVLSALVMGILWLSILFCRLYFHAHYFSDVIGGTSLAIIWVALFLMVYPYFIN
                     HRRQRV"
     gene            20022..20756
                     /locus_tag="RFE25_000776"
     CDS             20022..20756
                     /locus_tag="RFE25_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase"
                     /protein_id="HDU2815871.1"
                     /translation="MRIKTPSPSYLKGTNGHAILLLHSFTGTNRDVKHLAAELNDQGF
                     SCYAPNYPGHGLLLKDFMTYNVDDWWEEVEKAYQFLVNEGYESISATGVSLGGLMTLK
                     LAQHYPLKRIAVMSAPKEKSDDGLIEHLVYYSQRMSNILNLDQQASSAQLAAIDDYEG
                     EITKFQHFIDDIMTNLNVIKIPANILFGGKDEPSYETSAHFIYEHLGSVDKELNGLKD
                     SHHLMTHGEGRDILEENVIRFFNALT"
     gene            21128..22465
                     /locus_tag="RFE25_000777"
     CDS             21128..22465
                     /locus_tag="RFE25_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HDU2815872.1"
                     /translation="MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFL
                     AMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFG
                     FYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMII
                     VMLGVEKGLEKASKVMMPLLFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGIL
                     FALGQSFFTLSLGTTGMITYASYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHS
                     FGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALTSSISLLELNVSNFTK
                     NDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGA
                     LGTTLVIGQLLDKKLLQQYFGKDRFRLFNGWYYLIKYAMPVVIILVFIVQLFS"
     gene            22682..23587
                     /locus_tag="RFE25_000778"
     CDS             22682..23587
                     /locus_tag="RFE25_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000634108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDU2815873.1"
                     /translation="MITYDLIGNTPLVLLEHYSDDKVKIYAKLEQWNPGGSVKDRLGK
                     YLVEKAIQEGRVRAGQTIVEATAGNTGIGLAIAANRHHLKCKIFAPYGFSEEKINIMI
                     ALGADVSRTSQSEGMHGAQLAARSYAEKYGAVYMNQFESEHNPDTYFHTLGPELTSAL
                     QQIDYFVAGIGSGGTFTGTARYLKQHHVQCYAVEPEGSVLNGGPAHAHDTEGIGSEKW
                     PIFLERRLVDGIFTIKDQDAFRNVKSLAINEGLLVGSSSGAALQGALNLKAQLSEGTI
                     VVVFPDGSDRYMSKQIFNYEENDYE"
     gene            23580..24722
                     /locus_tag="RFE25_000779"
     CDS             23580..24722
                     /locus_tag="RFE25_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional cystathionine
                     gamma-lyase/homocysteine desulfhydrase"
                     /protein_id="HDU2815874.1"
                     /translation="MNKKTKLIHGGHTTDDYTGAVTTPIYQTSTYLQDDIGDLRQGYE
                     YSRTANPTRSSVESVIAALENGKHGFAFSSGVAAISAVVMLLDKGDHIILNSDVYGGT
                     YRALTKVFTRFGIEVDFVDTTHTDSIVQAIRPTTKMLFIETPSNPLLRVTDIKKSAEI
                     AKEHGLISVVDNTFMTPYYQNPLDLGIDIVLHSATKYLGGHSDVVAGLVATSDDKLAE
                     RLAFISNSTGGILGPQDSYLLVRGIKTLGLRMEQINRSVIEIIKMLQAHPAVQQVFHP
                     SIESHLNHDVHMAQADGHTGVIAFEVKNTESAKQLIKATSYYTLAESLGAVESLISVP
                     ALMTHASIPADIRAKEGITDGLVRISVGIEDTEDLVDDLKQALDTL"
     gene            25017..26042
                     /locus_tag="RFE25_000780"
                     /pseudo
     CDS             25017..26042
                     /locus_tag="RFE25_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
     gene            26046..26705
                     /locus_tag="RFE25_000781"
     CDS             26046..26705
                     /locus_tag="RFE25_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815875.1"
                     /translation="MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITR
                     KQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYV
                     APYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLI
                     GSTAMAGAVGGGGIGDLALVYGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRR
                     H"
     gene            26742..27584
                     /gene="gmpC"
                     /locus_tag="RFE25_000782"
     CDS             26742..27584
                     /gene="gmpC"
                     /locus_tag="RFE25_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter
                     glycylmethionine-binding lipoprotein"
                     /protein_id="HDU2815876.1"
                     /translation="MKRLIGLVIVALVLLAACGSNNDKKVTIGVASNDTKAWEKVKEL
                     AKKDDIDVEIKHFSDYNLPNKALNDGDIDMNAFQHFAFLDQYKKAHKGTKISALSTTV
                     LAPLGIYSDKIKDVKKVKDGAKVVIPNDVSNQARALKLLEAAGLIKLKKDFGLAGTVK
                     DITSNPKHLKITAVDAQQTARALSDVDIAVINNGVATKAGKDPKNDPIFLEKSNSDAV
                     KPYINIVAVNDKDLDNKTYAKIVELYHSKEAQKALQEDVKDGEKPVNLSKDEIKAIET
                     SLAK"
     gene            27916..28920
                     /gene="aaa"
                     /locus_tag="RFE25_000783"
     CDS             27916..28920
                     /gene="aaa"
                     /locus_tag="RFE25_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin/adhesin Aaa"
                     /protein_id="HDU2815877.1"
                     /translation="MQKKVIAAIIGTSAISAVAATQANAATTHTVKPGESVWAISNKY
                     GISIAKLKSLNNLTSNLIFPNQVLKVSGSSNSTSNSSRPSTNSGGGSYYTVQAGDSLS
                     LIASKYGTTYQNIMRLNGLNNFFIYPGQKLKVSGTASSSNAASNSSRPSTNSGGGSYY
                     TVQAGDSLSLIASKYGTTYQKIMSLNGLNNFFIYPGQKLKVTGNASTNSGSATTTNRG
                     YNTPVFSHQNLYTWGQCTYHVFNRRAEIGKGISTYWWNANNWDNAAAADGYTIDNRPT
                     VGSIAQTDVGYYGHVMFVERVNNDGSILVSEMNYSAAPGILTYRTVPAYQVNNYRYIH
                     "
     gene            complement(29105..29374)
                     /locus_tag="RFE25_000784"
     CDS             complement(29105..29374)
                     /locus_tag="RFE25_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815878.1"
                     /translation="MAKRSKSQRLSSLLNVAGFIVDGYNGYKYHAKNKKLVYLSLGLS
                     TVGTVLDFYISIKSPRKFKKAVAVVTLITNGARLFTSIRKVKHEY"
     gene            29523..29918
                     /locus_tag="RFE25_000785"
     CDS             29523..29918
                     /locus_tag="RFE25_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDU2815879.1"
                     /translation="MIKCVCLVEETADKILLVQVRNREKYYFPGGKIEEGESQVHALL
                     REVKEELNLTLTMDEIEYIGTIVGPAYPQQDMLTELNGFRALTKIDWENVTINNEITD
                     IRWIDKDNDALIAPAVKVWIETYGGKHDK"
     gene            29908..30393
                     /locus_tag="RFE25_000786"
     CDS             29908..30393
                     /locus_tag="RFE25_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2815880.1"
                     /translation="MTNNDTIMLRHYVPQDYSMLEAFQLSESDLKFVKTPEENITAAM
                     SDNERYPIVVMDGRQCVAFFTLHRGKGVAPFSDNQDAVFFRSFSVDQRYRNRGIGKVV
                     MEKLASFITSTFQDINEIVLTVNTDNPHAMALYRQQGYQYMGDSMFIGRPVHIMALTI
                     K"
     gene            complement(30562..31344)
                     /locus_tag="RFE25_000787"
     CDS             complement(30562..31344)
                     /locus_tag="RFE25_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDU2815881.1"
                     /translation="MNAVFILALLLLFLMIIFGGKKGFISYLTLFLNFAILIISIVLI
                     IFGVPIYVVTFFFCIIIGACNLFVLNSYNVKTQAAFISTIVTTILLITLIYLSVYFGH
                     LQGFSTEQQDETYVYSMNIGIDMVQFMVFTIILAVIAAVIDLTITISSPIYELHQVNP
                     TLTQYELFQSGMRVGREILATSANTIYLAFFGGQLALFIWFFKLKYSFGHIINSKIFA
                     QEFISIILGGIAVAISIPITAWITAFLIKRPSRQRKNDESIN"
     gene            complement(31341..32459)
                     /locus_tag="RFE25_000788"
     CDS             complement(31341..32459)
                     /locus_tag="RFE25_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDU2815882.1"
                     /translation="MFLKYRNLFTKPFNIILGLFCIAFIGAILFTFNNENFYNKPIGQ
                     IIDVKHVSSTPTKDAQNNRDIKYKNQLKVKILNGQFAGETTTINHQYVKSQADSEAFR
                     THEKVLLHISNKPSDAYIIEKKRDTLTVIITGLFLLTVLLVGRKVGLQSILSLILNSI
                     AILIAIYIHIQHSNINLFLLMTIAMICSTILTLLLVTGWHMRTLITIASTIIGTFLSI
                     GLTELIIYMTDGKGIKYETMNFLSLPPKDIFLASVLIGSLGAIMDVAITIASGMHEIL
                     QRTPHISMRRWALAGRNIGQDIMGTMTNILLFSYLSGALPMFLIFLKNANTVTYTISM
                     NWSLEIARALTGGIGIVLTIPITILFMEIFETLRRAKQ"
     gene            complement(32574..33458)
                     /locus_tag="RFE25_000789"
     CDS             complement(32574..33458)
                     /locus_tag="RFE25_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDU2815883.1"
                     /translation="MEIKQLRYFIEVAKREHISETALELNIAQSAISRQITLLEQELN
                     VSLFKKQGRNITLTSEGKLLFNEALRIIEHLDSTIEQFQSHGLTKNKSIYIGYDESDV
                     SHMLLPLIQTFHLQNDTHVIPSLLDHDTIINSVLNGNIDIGFTELTPEIRKHKQLHML
                     PLFEEHYHLYAPSDDPITMATHPPLIQFEHSHIYCLAPFAETVKKQLRKITKSDVYTI
                     SSQPLAQYLLRQKEGYIISSQNIHLPESKSWIDIKLDHTELKRTICAITKEPYTKSDI
                     GILLTLIQQLMTKTSTFH"
     gene            33639..38138
                     /gene="gltB"
                     /locus_tag="RFE25_000790"
     CDS             33639..38138
                     /gene="gltB"
                     /locus_tag="RFE25_000790"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HDU2815884.1"
                     /translation="MHNEKLIKGLYDYREEHDACGIGFYANMDNKRSHDIIDKSLEML
                     RRLDHRGGVGADGITGDGAGIMTEIPFAFFKQHVTDFDIPGEGEYAVGLFFSKERILG
                     SEHEAVFKKYFEGEGLSILGYRNVPVNKDAIAKHVADTMPVIQQVFIDIRGIEDVEKR
                     LFLARKQLEFYSTQCDLELYFTSLSRKTIVYKGWLRSDQIKKLYTDLSDDLYQSKLGL
                     VHSRFSTNTFPSWKRAHPNRMLMHNGEINTIKGNVNWMRARQHKLIETLFGEDQHKVF
                     QIVDEDGSDSAIVDNALEFLSLAMEPEKAAMLLIPEPWLYNEANDANVRAFYEFYSYL
                     MEPWDGPTMISFCNGDKLGALTDRNGLRPGRYTITKDNFIVFSSEVGVVDVPESNVAF
                     KGQLNPGKLLLVDFKQNKVIENNDLKGAIAGELPYKAWIDNHKVDFDFENIQYQDSQW
                     KDETLFKLQRQFAYTKEEIHKYIQELVEGKKDPIGAMGYDAPIAVLNERPESLFNYFK
                     QLFAQVTNPPIDAYREKIVTSELSYLGGEGNLLAPDETVLDRIQLKRPVLNESHLAAI
                     DQEHFKLTYLSTVYEGDLEDALEALGREAVNAVKQGAQILVLDDSGLVDSNGFAMPML
                     LAISHVHQLLIKADLRMSTSLVAKSGETREVHHVACLLAYGANAIVPYLAQRTVEQLT
                     LTEGLQGTVVDNVKTYTDVLSEGVIKVMAKMGISTVQSYQGAQIFEAIGLSHDVIDRY
                     FTGTQSKLSGISIDQIDAENKARQQSDDNYLASGSTFQWRQQGQHHAFNPESIFLLQH
                     ACKENDYAQFKAYSEAVNKNRTDHIRHLLEFKACTPIDIDQVEPVSDIVKRFNTGAMS
                     YGSISAEAHETLAQAMNQLGGKSNSGEGGEDAKRYEVQVDGSNKVSAIKQVASGRFGV
                     TSDYLQHAKEIQIKVAQGAKPGEGGQLPGTKVYPWIAKTRGSTPGIGLISPPPHHDIY
                     SIEDLAQLIHDLKNANKDADIAVKLVSKTGVGTIASGVAKAFADKIVISGYDGGTGAS
                     PKTSIQHAGVPWEIGLAETHQTLKLNDLRSRVKLETDGKLLTGKDVAYACALGAEEFG
                     FATAPLVVLGCIMMRVCHKDTCPVGVATQNKDLRALYRGKAHHVVNFMHFIAQELREI
                     LASLGLKRVEDLVGRTDLLQRSSILKANSKAASIDVEKLLCPFDGPNTKEIQQNHNLE
                     HGFDLTNLYEVTKPYIAEGRRYTGSFTVNNEQRDVGVITGSEISKQYGEAGLPENTIN
                     VYTNGHAGQSLAAYAPKGLMIHHTGDANDYVGKGLSGGTVIVKAPFEERQNEIIAGNV
                     SFYGATGGKAFINGSAGERFCIRNSGVDVVVEGIGDHGLEYMTGGHVINLGDVGKNFG
                     QGMSGGIAYVIPSDVEAFVENNQLDTLSFTKIKHQEEKAFIKQMLEEHVSHTNSTRAI
                     HVLKHFDRIEDVVVKVIPKDYQLMMQKIHLHKSLHDNEDEAMLAAFYDDSKTIDAKHK
                     PAVVY"
     gene            38156..39619
                     /locus_tag="RFE25_000791"
     CDS             38156..39619
                     /locus_tag="RFE25_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit beta"
                     /protein_id="HDU2815885.1"
                     /translation="MGEFKGFMKYDKQYLGELSLVDRLKHHKAYQQRFTKEDASIQGA
                     RCMDCGTPFCQTGQQYGRETIGCPIGNYIPEWNDLVYHQDFKTAYERLSETNNFPDFT
                     GRVCPAPCESACVMKINRESIAIKGIERTIIDEAFENGWVAPKVPSRRRDEKVAIVGS
                     GPAGLTAAEELNLLGYQVTIYERARESGGLLMYGIPNMKLDKDVVRRRIKLMEEAGIT
                     FINGVEVGVDIDKATLESEYDAIILCTGAQKGRDLPLEGRMGDGIHFAMDYLTEQTQL
                     LNGEIDDITITAKDKNVIIIGAGDTGADCVATALRENCKSIVQFNKYTKLPEAITFTE
                     NASWPLAMPVFKMDYAHQEYEAKFGKEPRAYGVQTMRYDVDDKGHIRGLYTQILEQGE
                     NGMVMKEGPERFWPADLVLLSIGFEGTEPTVPNAFNIKTDRNRIVADDTNYQTNNEKV
                     FAAGDARRGQSLVVWAIKEGRGVAKAVDQYLASKVCV"
     gene            39888..39980
                     /locus_tag="RFE25_000792"
     tRNA            39888..39980
                     /locus_tag="RFE25_000792"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39924..39926,aa:Ser,seq:tga)
     gene            40449..41876
                     /gene="treP"
                     /locus_tag="RFE25_000793"
     CDS             40449..41876
                     /gene="treP"
                     /locus_tag="RFE25_000793"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HDU2815886.1"
                     /translation="MAVKREDVKAIVSAIGGKENLEAATHCVTRLRLVLKDESKVDKD
                     ALSNNALVKGQFKADHQYQIVIGPGTVDEVYKQFIDETGAQEASKDEAKQAAAKKGNP
                     VQRLIKLLGDIFIPILPAIVTAGLLMGINNLLTMKGLFGPKALIEMYPQIADISNIIN
                     VIASTAFIFLPALIGWSSMRVFGGSPILGIVLGLILMHPQLVSQYDLAKGNIPTWNLF
                     GLEIKQLNYQGQVLPVLIAAYVLAKIEKGLNKVVHDSIKMLVVGPVALLVTGFLAFII
                     IGPVALLIGTGITSGVTFIFQHAGWLGGAIYGLLYAPLVITGLHHMFLAVDFQLMGSS
                     LGGTYLWPIVAISNICQGSAAFGAWFVYKRRKMVKEEGLALTSCISGMLGVTEPAMFG
                     VNLPLKYPFIAAISTSCVLGAIVGMNNVLGKVGVGGVPAFISIQKEFWPVYLIVTAIA
                     IVVPCILTIVMSHFSKQKAKEIVED"
     gene            41940..43580
                     /gene="treC"
                     /locus_tag="RFE25_000794"
     CDS             41940..43580
                     /gene="treC"
                     /locus_tag="RFE25_000794"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDU2815887.1"
                     /translation="MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLL
                     GVDYIWLTPVYESPMNDNGYDISNYLEINEAFGTMDDFEKLIKVAHQKDLKVMLDIVI
                     NHTSTEHEWFKEARKSKDNPYRDYYFFRSSEDGPPTNWHSKFGGNAWKYDSETDEYYL
                     HLFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKE
                     FYTDGPRVHEFLHELNRQTFGNTDMMTVGEMSSTTIENCIKYTQPERQELNSVFNFHH
                     LKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWCNHDQPRVVSRFGDD
                     TSEEMRIQSAKMLAIALHMLQGTPYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLL
                     SEGHAEADVLAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQ
                     NKESIFYTYQKLIQLRHTHDIITYGDIVPRFMDHDHLFVYERHYKNQQWLVIANFSAS
                     AVDLPEGLAREGCVVIQTGTVENNTISGFGAIVIETNA"
     gene            43605..44333
                     /gene="treR"
                     /locus_tag="RFE25_000795"
     CDS             43605..44333
                     /gene="treR"
                     /locus_tag="RFE25_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDU2815888.1"
                     /translation="MAKQKKFMKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRE
                     TVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFSELVSFKEMQEEMGVAYLTEVVV
                     NEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVA
                     SDSIYDYLEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMP
                     FQYNISKHLANEFKFNDFSRRRIK"
     gene            44395..44664
                     /gene="ffs"
                     /locus_tag="RFE25_000796"
     ncRNA           44395..44664
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RFE25_000796"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            44737..44838
                     /locus_tag="RFE25_000797"
     CDS             44737..44838
                     /locus_tag="RFE25_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815889.1"
                     /translation="MKTIQRIIRGTCLWEVAFLYVKFDSSELDVQFE"
     gene            44976..45500
                     /locus_tag="RFE25_000798"
     CDS             44976..45500
                     /locus_tag="RFE25_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDU2815890.1"
                     /translation="MQIYLSTLTELDYDKSLNSIEESFDDNPETSWQARAKVKHLRKS
                     PCYNFELEVIAKNENNDVVGHVLLIEVEINSDDKTYYGLAIASLSVHPELRGQKLGRG
                     LVQAVEERAKAQEYSTVVVDHCFDYFEKLGYQNAAEHDIKLESGDAPLLVKYLWDNLT
                     DAPHGIVKFPEHFY"
     gene            45569..47266
                     /gene="dnaX"
                     /locus_tag="RFE25_000799"
     CDS             45569..47266
                     /gene="dnaX"
                     /locus_tag="RFE25_000799"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDU2815891.1"
                     /translation="MNYQALYRMYRPQSFEDVVGQEHVTKTLRNAISKEKQSHAYIFS
                     GPRGTGKTSIAKVFAKAINCLNSTDGEPCNECHICKGITQGTNSDVIEIDAASNNGVD
                     EIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH
                     KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQQIECEDEALAFIAKASEGGMRDAL
                     SIMDQAIAFGDGTLTLQDALNVTGSVHDEALDHLFDDIVQGDVQASFKKYHQFITEGK
                     EVNRLINDMIYFVRDTIMNKTSEKDTEYRALMNLELDMLYQMIDLINDTLVSIRFSVN
                     QNVHFEVLLVKLAEQIKGQPQVIANVAEPAQIASSPNTDVLLQRMEQLEQELKTLKAQ
                     GVSVAPAQKSSEKPARGIQKSKNAFSMQQIAKVLDKANKADIKLLKDHWQEVIDHAKN
                     NDKKSLVSLLQNSEPVAASEDHVLVKFEEEIHCEIVNKDDEKRSSIESVVCNIVNKNV
                     KVVGVPSDQWQRVRTEYLQNRKNEGDDMPKQQAQQTDIAQKAKDLFGEETVHVIDEE"
     gene            47356..47673
                     /locus_tag="RFE25_000800"
     CDS             47356..47673
                     /locus_tag="RFE25_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002479279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDU2815892.1"
                     /translation="MRGGGNMQQMMKQMQKMQKKMAQEQEKLKEERIVGTAGGGMVAV
                     TVTGHKEVVDVEIKEEAVDPDDIEMLQDLVLAATNEAMNKADELTQERLGKHTQGLNI
                     PGM"
     gene            47680..48276
                     /gene="recR"
                     /locus_tag="RFE25_000801"
     CDS             47680..48276
                     /gene="recR"
                     /locus_tag="RFE25_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009383386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDU2815893.1"
                     /translation="MHYPEPISKLIDSFMKLPGIGPKTAQRLAFHTLDMKEDDVVQFA
                     KALVDVKRELTYCSVCGHITENDPCYICEDKQRDRSVICVVEDDKDVIAMEKMREYKG
                     LYHVLHGSISPMDGIGPEDINIPSLIERLKSDEVSELILAMNPNLEGESTAMYISRLV
                     KPIGIKVTRLAQGLSVGGDLEYADEVTLSKAIAGRTEM"
     gene            48481..48586
                     /locus_tag="RFE25_000802"
                     /pseudo
     CDS             48481..48586
                     /locus_tag="RFE25_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499028.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        17256 a         6748 c         9966 g        15057 t
ORIGIN      
        1 tttggtaacg taaaagagaa atatacaaaa taattaatta tttatatgaa aagagaatat
       61 aaatgaagta taaaacaaag agacgtgaaa cgatgcgata tttaaaaaga ctttcatggt
      121 acataagcat cttaatttta atagttgtta tagctggttg tggcaaaggt aatgaaacaa
      181 aagaaggttc aaaagaagaa caaatcaaaa agagctttgc gaaaacgtta gatatgtatc
      241 caatcaaaaa tctcgaggat ttatacgaca aagaaggata tcgagatagc gaatttaaaa
      301 aaagtgataa agggacatgg acgatataca cagatttcgc taaaagtaat aaaccgggtg
      361 aattggatga tgaaggtatg gttttaaatc tggataggaa tactagaacc gctaaaggcc
      421 attattttgt tactacattt taccggaatg gtaaactacc agatgaaaag aattataaaa
      481 ttgaaatgaa aaataataag attattttat tagatgaagt aaaagatgat aagctcaagc
      541 agaaaataga aaactttaaa tttttcggtc aatatgcaaa tcttaaagaa ttgagaaaat
      601 ataataatgg tgatgtttca attaatgaaa atgttcctag ttatgatgtt gaatacaaaa
      661 tgagcaataa agatgaaata gttaaggaat taagaagtcg ttataatatt tcgactgaaa
      721 aatcacctat attaaaaatg catattgatg gggacctgaa aggcagttct gtaggttata
      781 gaaagttaga aattgacttt tcaaaacgtg aaaacagcaa attatcagtc attgaatttt
      841 taagttataa accagcgaaa aaatagtatt gataaggaat attaggatgt gaaaaaatgg
      901 gatatctaaa aaagcttgca ctgttcataa gtgttattat tttgggcatt tttataatag
      961 gttgtgatag ttcaagcgat actgcggaaa aagcaaaaga agattcaaaa gaagaacaaa
     1021 tcaaaaagag ctttgcgaaa acgttagata tgtatccaat taagaatctc gaggatttat
     1081 acgacaaaga aggatataga gatggtgaat ttaaaaaggg cgataagggg acttggactt
     1141 tactcacaag tttttcaaaa agtaacaaac cgggtgaaat agatgacgaa ggcatggttt
     1201 tatatctaaa tagaaatacc aaaaaggcaa caggttatta ttttgtaaat aaaatttatg
     1261 atgatattag caaaaatcag aatgagaaaa aataccgtgt tgaacttaaa aataataaga
     1321 ttattctttt ggataatgta gaagacgaaa aacttaaaca aaaaattgaa aattttaaat
     1381 tttttagtca gtatgccgat tttaaagatt taaaaaatta tcaagatgga agtataacaa
     1441 ctaatgaaaa tgtaccgaga tatgaagcag aatacaaatt gaataatagt gatacaaatg
     1501 taaaaaaact tagagatatt tatccaatta caacgaaaaa ggctccaata ttaaagttac
     1561 atatagatgg tgatataaaa ggaagttcag ttggatacaa aaaaatagaa tataaatttt
     1621 caaaagttaa agatcaagag acaacattaa gagattattt aaattttggg ccgtctgatg
     1681 aagatagcta aagtttatta gatgtagaaa taattctaaa gcagagagac gtgaaatgat
     1741 gggatattca aaaaggtttg cattgtacat aagcgttatg attttaatat ttgcgatagc
     1801 aggttgtggc aaaagtgatg aaacaaaaga aggttccaaa gaagaacaaa ttaaaaagag
     1861 ctttgcgaaa acgttagata tgtacccaat taagaatctc gaggacttat atgacaaaga
     1921 aggatatcga gatggcgaat ttaaaaaggg tgacaaaggg acatgggtta tcagttcagt
     1981 aatggttaaa cagccaaaag gtgaaattat gaaatcaaga gggatgtatc tatttttaaa
     2041 tagaaataca agaaccgcaa aaggatattt tattgtagat gaaacaagta atgatacttt
     2101 aaaaaaaaca gaggataaag aaaaacgtta tccagtaaag atggtgaata ataaaatagt
     2161 acctattgat ccaattaatg ataaaggtgt aaaaaaagaa atagaaaatt ttaagttttt
     2221 ctcacaatat ggtgatttta aagaattaaa aaattataaa aatggagagg tttcatacaa
     2281 ttctgaagcc cctatctact cagcaaaata tcaactgaaa aataatgatt ataatgtaaa
     2341 gcaattacgt aaaagatatg atatatcaac agaaaaggct cccaaattgt tgttgaaagg
     2401 tactggagat ttaaaaggtt catcaatcgg acataaggac attgagttta cattcgtgga
     2461 gaatcaagaa gagaatatat tttttactga tagtttggag tttacctcaa gtgagaacta
     2521 ttagctatga taaaaaaagg ggatacggaa caatgaataa ttttagaaaa tgtgcgttgt
     2581 gtataggacg tcagtcttaa ttctattagc atcaggttgc agtggcgtat ttgacactcc
     2641 tgaagattca aaagaaacac aaatcaaaaa gagctttgcg aaaacgttag atatgtatcc
     2701 aattaaaaat cttgaggatt tatacgataa agaaggatat cgagatggag aatttaaaaa
     2761 gggagacaaa gggacgtggg ttgttagatc tgaaatgata attcaaccaa aaggtaaaag
     2821 tttaacttca agaggcatga tattatacat gaatagaaat actaggacca caaccggtta
     2881 tttttcaata gaagaaatag attcaagaaa aagccttgat gaaagagaaa cagaaaaaaa
     2941 gtatcctgtg aaaatgataa acaataaaat tattccaact gaggagataa aagatgaaaa
     3001 gttgaaaaag gaaattgaaa actttaagtt ttttgtgcaa tatggcagtt ttaaaggaat
     3061 agagaattat gaaaatggtg acatttccta taattctgaa gctcctattt attcagcgaa
     3121 atataaactg aaaaatgatg attataatgt taaagaatta cgaaaaagat ataatattcc
     3181 aacagaaaag gcgcctaaat tgttgttgaa aggttcgggg gatttgaaag ggtcttcagt
     3241 tggatataag gaaattgaat ttatatttat agaaaataaa aaagaaaata tatatttttc
     3301 agatggatta aacttaattc caagtgacta aaaataacac aaaggttgat agtactcaac
     3361 aaatattaac atgatagaga gaagtgaaaa aatgagggat tcaaaaagag tagtattgta
     3421 cataagcatt atggtgttga gtatttttat aattggttgt ggcaaaggta atgaaataaa
     3481 agaagacgca aaggaagaac aaatcaaaaa gagctttgcg aaaacgttag atatgtatcc
     3541 aatcaaaaat ctcgaggacc tatatgataa agaaggatat cgagatggcg aatttaaaaa
     3601 aggtgacaaa gggatgtgga cgatttacac agatttcgcc aaaagtaata gaccaggtgt
     3661 attagataat gaaggtatgg ttttaaattt ggatagaaat acacgaacgg ccaagggata
     3721 ttattttgta gatactatat atgacaatca tgaaaactct tatagtaaaa attatagagt
     3781 tgagatgaaa aacaataaaa ttattttatt agacaaggtg gaagatcaaa aacttaaaga
     3841 aagaatagaa aactttaaat ttttcggaca atatgccgat ttcaagagtt tgaaaagtta
     3901 caaccatggc gacgtttcaa ttaatagtaa tgttccaagt tatgacgcga aatttaaaat
     3961 gagtaataaa gatgaaaatg ttaagcaatt aagaagccgt tataacattc ctactgataa
     4021 agctccaata ttaaaaatgc atattgatgg ggacttaaaa ggcagttccg ttggatataa
     4081 aaagttagaa atagactttt caaaagaaga aaatagcgaa ttatcaatag tcgattcatt
     4141 aaattttcaa cctgccaaaa ataaagatga tgaatgatag ggaggatgtg aagcgatggg
     4201 atattcaaaa aggtttgcat tgtacataag tatcttgatt ttaatagtta tggtagcagg
     4261 ttgtggtaaa agtgatgaaa caaaagaaga ttccaaagaa gaacaaatta aaaagagctt
     4321 tgcgaaaacg ttagatatgt accctattaa gaatctcgag gatttatacg ataaagaagg
     4381 ataccgtgat ggcgaattta aaaagggtga taaggggacg tgggttctgt attcagctat
     4441 agtatcacaa ccaaaaggcg agagtttaaa atcacgagga atgatattaa agttagatag
     4501 aaataagaga actgctaaag gaagttatat tattagagaa ttgaaagaag ataaaaatca
     4561 tgatgttcaa aaaaatgaaa agaaatatcc agtgaaattg gtgaataata ggatagtttt
     4621 ggtaaaagat gttaaagaca aaaagttaaa aaatgaaata gagtcgtttg aattattttc
     4681 acaatatgga aactttaatc attttgatcg gaatgagatt actaatattt catataatcc
     4741 taatgctccc aattactctg cagaatataa aatgaagaaa aatgacagaa acattcaaca
     4801 gttgaaaaag agatttaatc taaaaactag caagacacca aaattattgt ttaagggatc
     4861 tggagatata aaggggtctt ctgtaggata taaggaaata gaaatcatat ttagtagaag
     4921 taaagaagaa gcatttatta tgttgacagc gttgagttcg ttccaagtaa caaaatgaca
     4981 aaaagttgat attagtcaac aaaagcaaat attgagaata aagagagttg tgaaatgatg
     5041 ggttatttaa aaagacttgt attgtacata gttattatgg ttatgagtgt ttttataata
     5101 ggttgtgata aatcaagcga tactgcagaa aatccaaaag aaggttcaaa agaagcacaa
     5161 attaaaaaga gtttttcgaa aacgttagat atgtatccaa ttaagaatct cgagaatcta
     5221 tatgacaaag aaggatatcg tgatggcgaa tttaaaaaag gtgataaagg gacttggaca
     5281 atatcaacag attttgctaa aagcaacaag caaggtgaaa tgaatagcga aggtatggta
     5341 ctacatttta atagaaatac gaggacagca acaggatatt atactgtaag aacaacttat
     5401 gatgaagtgg ataagttggc acgcgaaaaa aaatatcgtg ttgaatttaa aaacaataag
     5461 atagttctat tggacaaagt agaagatgaa aatcttaaac aaaaaataga aaattttaaa
     5521 tttttcgggc aatatgccga ttttaaagac ttgaaaaatt ataaaaatgg aagaatatct
     5581 agcaatgaaa atgttcctta ttatgaagca gagtacaaaa ggaataatag tgatggaaat
     5641 gtaaaaaaac ttagagaaaa gtacccaatt acaaccaagc agtctccaat attaaaactg
     5701 catatagacg gcgatattaa aggtagctca gttggatata aacagataga atacacattt
     5761 tctaaggaga aagatgatga gacttttatg agtgattttt tgaacttcgg tccatcacac
     5821 agtaaatagt aaataaaacc aagggcataa actaatttaa aacaagagag aagtgaaaag
     5881 atgggatatt ttaaaagagt tgtactttac ataattgtta tggttgtgag tgtttttata
     5941 ataggttgca ataaatcaag cgatacttca gaaaagccaa aagaagattc aaaagaaaca
     6001 caaatcaaaa agagctttgc gaaaacgtta gatatgtatc caattaagaa tctcgaggac
     6061 ttatatgata aagaaggata ccgtgatggc gaatttaaaa agggtgacaa aggaatgtgg
     6121 actatatata cagattttgc taaaagtaat aaacaaggtg gattgagtaa tgaaggtatg
     6181 gtcttatact tagatagaaa tacacggact gcaaagggac attattttgt taagacattc
     6241 tataataagg gcaaattccc agatagaaaa aattataaag ttgaaatgaa aaataataaa
     6301 attatcttat tagataaagt agaagatata aatctaaaaa agagaataga aaactttaaa
     6361 ttttttggac aatatgcaaa tcttaaagaa ttgaaaaatt acagcaatgg tgatgtctca
     6421 attaatgaga atgttccaag ttatgacgca aaatttaaaa tgagcaataa agatgaaaat
     6481 gttaagcaat taagaagtcg ttataatatt cctactgata aagcaccggt attaaaaatg
     6541 catattgatg gtgatttgaa aggaagttct gtgggttata aaaagttgga aattgacttt
     6601 tcaaaaggtg aaaaaagcga tttgtcagta atagattctt taaatttcca gccggcgaag
     6661 gtggatgaag atgatgaatg atgaggatgg tgtgtaacaa tgaagtctat aaaaaggatt
     6721 ggattgtgca taagtctgtt gattttaatc atttttgcaa catcttgtgg tagtaataag
     6781 attactggag actcaaaaga agaacaaatc aaaaagagtt ttgcgaaatc tttagacaag
     6841 tatcctactg aaaatctaga agagttttat gataaagaag gatatagaga tggagaattt
     6901 gaaaaagatg ataaagggac ttggctaatt agatctgaaa tgaaaatcca attaaaagga
     6961 gaaaatctgg aatctagggg agcagttata gaaattaaca gaaatactag aacggctaaa
     7021 gggaattata ttgttagaga agttgttgaa gatagcgatg gaatgacaca caatcataca
     7081 aaaaggtatc ctgtgaaaat ggaaaataat aaaatgattc cattaaaatc aattgatgat
     7141 gaaaaagtaa aaaaagaaat tgaagaattt aaattctttg tacaatacgg gaatttcaaa
     7201 gaattggaaa actataaaga ggacgaagtg tcatataacc cagaagtacc aatatactct
     7261 gcacaatatc aattgaaaaa cagtgattat aatgtagagc aattacgtaa gcgatataat
     7321 atcccgacgc aaaaagcgcc caaattatta ttgaaaggct caggtaattt aaaaggttca
     7381 tcagtcggat ataaaaatat tgaatttacc tttgttgaaa ataaggaaga aaatatttac
     7441 ttcacagata gtgtctactt taatccaagc gaggataaat aagtataatt attattataa
     7501 aaaatgacgt tagaacattt aataataaag ttaaatgaat tacatgtatt aaattgaata
     7561 agttagtttt gtttgataac ataaaagttg aataatcact attttaataa gttatatgaa
     7621 atattcaaat gtttataaaa ttaaagcaga gagatgtgaa atgatggagt atataaaaaa
     7681 aattgctttg tacatgagtg tattactttt aatcattttt attgggggat gtggaaatat
     7741 gaaagaagaa cagaaaaaag aagcaaatac aaataaaaca gattcaaaag aagaaaaaat
     7801 caaaaagagt tttgcgaaaa cgttagatat gtatccaatt aagaatctcg aggaactata
     7861 tgacaaagaa ggctatcgag atggcgaatt tgaaaaaggt gacaaaggga tgtggacgat
     7921 atatacagat ttcgccaaaa gtaataaacc gggtgaacta agtaatgaag gcatggtctt
     7981 gtacttagat agaaacacac gcacagctaa ggggtactac tttgtcagga cgttttatcg
     8041 caaggataaa ttacctgata gaaaaaatta taaagttgaa atgaaaaata ataaaattat
     8101 cttattagac aaggtagaag atccaaatct aaaaaagaga atagaaaact ttaaattttt
     8161 cggacaatat gcaaatctta aagaattgaa aaactacagc aatggtgatg tctcaattaa
     8221 tgagaatgtt ccaagttatg acgtgaaata taaaatgagt aataaagatg aaaatgttaa
     8281 gcaattaaga agtcgttata atattcctac tgataaatca ccggtattaa aaatgcatat
     8341 tgatggtaat ttgaaaggaa gttccgttgg agataggaag ttagaaattg atttttcgaa
     8401 acgtgaaaat agccatttat cagtaataga ttctttggat taccagccag cgaaggtgga
     8461 tgaagatgaa agataaatac aaaatagatc cagggattat taaaaataat acagaggaaa
     8521 ctacagctat ttctaaaatc agctacgaag ttgaaaatgc gaatttatat ggagctgata
     8581 gtgaagatat aacaagacaa atagaatatt tgaaagccaa aaaaaaattc ccttctaatc
     8641 ttgaatatgt tgatagttac actgattctc ttaatggagt aacaacttct gcttttttaa
     8701 ataaagatac aggcaaagta actcttggga tgactgggac taatatacaa ggcgaagcct
     8761 ttaaaaagtt aaaagaaggt gaattttcaa gacaaaatgt taccaatgct ttggaaacag
     8821 ttaaagatgg atatgcagat cttaaaatat tatattctcc tgcatctgat caaaactata
     8881 gatatgcgaa tacacaagaa tttataaata aaataaaaag taagtatgac attgatttta
     8941 ttactggtca ttcactaggt ggaagagatg cggtagttct tggaatgagt aatggtattc
     9001 cgaacattgt ggtttataat ccagctccta tttctataaa tagtttgaat cctaattccc
     9061 cagatggaaa acgattgtta gagttatata aaaattataa aggtaatatt actaggtttg
     9121 ttgcagaaaa tgatgcattg acagaaaatc tgaagaaata taagcattat gttttttttg
     9181 gtaatgataa agtctttaaa aatggtaaag gtcatgaaat ggaaggcttt ctgaccgaag
     9241 aagaacaaaa agctataaaa aaagaactta aaaaactaca aggttatgca gaagaaaata
     9301 ataagtcatt tgtaaagaat tcaaataatg ctatctctaa attagctagt atagaattac
     9361 ttagagcaaa tatgatgact acaaatggag gaggattatc ttcttcgcag caaaaagttt
     9421 tagaaagttt aacagcttta acaattgcgc agtcattcag tcaactgata gacgatgaaa
     9481 ttaatcaaat caaaaaaatg tataatgaaa agaaaaagga atttggaaaa aattgggaag
     9541 acgctcaaaa agctggaaaa gctgtaggtg aagatttgag tgtaaatgga gttctcaatg
     9601 ctttagatga aggtcaagtg aatgaaagta gtatggtaag agaacctgaa caaatgatat
     9661 ctgcaaaaga aagacaactt tcaacgatag ggtcttctgt atcaaattat attatgagag
     9721 ttagactcag tattaatgaa atcgttgata aagatcaagt gcttgcatca caaataggtg
     9781 gattactatg atgtttaatc aaattaataa taaaaatgaa ttagaagaat catatgaatc
     9841 tgagaaaaaa cgtatagaga atgaactgca taatttaaat gaacttaggc atagaactcg
     9901 aaaagaaaat gaacgtagtt atgatgtttt tcaatatttg aagcacgaaa tgaattatag
     9961 tgaagatgcc caaaggaaaa tgacgagaaa tatagaagcg tatgagcaag aaatcaatga
    10021 gataattaga aagcaagaat ggaaattaga agaatataaa gaagacttaa aaaagtctta
    10081 tgaaaagcag ttagataaac taagtgactg ataatttgga ggagattaaa tgactctaat
    10141 agaaccagat atgaacttaa gaatgccaga tataagtact acagtagaaa cacttaatct
    10201 catatctaaa atggaagcgc aaaaagaaaa cattcgttca gttattgcac ctgaacataa
    10261 gcataaatat aaagatattg aaaacggatt aaaaggtgaa gaaaaagtat tgattgaaca
    10321 aatggcgcag cattgcgaag cttttaaagc taattttaaa ggtgcagctc aaggagactg
    10381 ggttaaaagt gcaatgtctg agatagacag tattaaagat gatttgaaaa aaattaatag
    10441 ctaaactaca tatcatacta ctaaataaag cgaccaatgt tcagtatatt cacaactgac
    10501 actaggccgc ttctttttaa tttattttat ttccatgtaa agtaacgctc tcttaatcga
    10561 aataccacac tcacaattgt aaaaacacaa cttaaattac tgtcccgcat taaacatatc
    10621 tacattccaa acagcaacaa caaaatcctc aagtaccaaa agctatgacc actttatcaa
    10681 aatcaacgca agttaacctc tcccgaacta cccgctatag atcatcatca ccttacaaac
    10741 cataaagcgc tgcagttaag tattgaatag catagccaat tgaaatgaaa atagcaatcg
    10801 ttataatggc actaccaatt gtatataaag tatgtttcgt agataaacct tccgtcttag
    10861 aaccaaaaac acttagtaga ataaatgcaa tgccaatgac atataaaact aaaatgacaa
    10921 ataacatgtt tatacacctc gattctcttt agtgagatat atctttgtct ccattataaa
    10981 gtaaagtgct caataattta attaagtata ctattttttt attatcgaag attgcgaaag
    11041 aggaaacgct cctatataat gtaaaacgga attattccta tttacaaata aattgaagtg
    11101 agggtatata tatggctaaa attccagtta cggtattaag tggttattta ggctcgggga
    11161 aaacaacatt gttaaatcat attttacaaa atcgtgaagg tcgacgtatc gcggtaattg
    11221 taaatgatat gagtgaagtt aatatcgata aagatcttgt cgcagatggt gggggactat
    11281 cgcgtacaga tgaaaaatta gtcgaactct ctaatggttg tatctgttgt acacttagag
    11341 atgatttatt aaaagaagtt gagcgtttag tgaaaaaagg tggcatcgat caaattgtta
    11401 ttgagtcaac agggatttca gagccagtac ctgttgcaca aactttctca tatattgatg
    11461 atgaacttgg cattgatctt acagcgattt gccgtttaga tacaatggtt acagttgttg
    11521 atgctaaccg cttcgtacat gacatcaact cagaagattt attgatggat cgtgatcaaa
    11581 gcgttgatga aacagatgaa cgttcgattg ctgatttatt aattgaccaa gttgaatttt
    11641 gtgatgtatt gattattaat aaaattgatt taattagtga agaagaactt gcaaagttag
    11701 aaaaagtgtt aagcgcattg caacctattg ctaaaattat taagacaaca aattctgaag
    11761 tagatttaaa agaagtctta aatacgcagc gttttgattt tgaaaaagcg agcgagtcag
    11821 caggatggat caaagaactt gagtcgggtg gtcatgcatc gcatacgcct gaaacagaag
    11881 aatatggcat atcatcattt gtatataaac gtcgtctacc tttccatgct aaaaggttca
    11941 atgattggtt agaaagcatg tcaaataatg tcgttcgatc aaaaggtatc gtatggttag
    12001 cacaatacaa tcatgtagca tgtttattat ctcaagcagg gtcatcttgc aatattcacc
    12061 cagttacata ttgggtggct agtatgtctg aagcgcaaca aacacaaata ttagcagaac
    12121 gtcaagatgt cgcagctgaa tgggatccag aatatggcga tcgtcataca caatttgtca
    12181 ttattggtac agaattagat gaagaaaaat taacaaaaga actcgatgca tgcttagtca
    12241 atgcgcaaga aattgatgca gattggcaac aatttgaaga tccatatcaa tggcaaatta
    12301 gaccagcacg ataagttgaa tgaagtataa tcatttttga attgtggctt aattgtttgc
    12361 aatttatgac aattaataaa aagttaagat gttcttagga actttttgtt ttcaatctat
    12421 ctaaagtgtg atagttttga taaagcagaa atttgcattt tatccatagg gctaggacat
    12481 gtatgtgtct tagtcctttt tatatttgcg ttgatgaaaa atgataaaac catcgtacca
    12541 actgttaatt gaaagtacaa ttattgttta acggtcataa aaatgagtga agtaattgca
    12601 gctatcaatg tactattact gcttacagtc acacgagtgt ttcagactaa acgtgcaacg
    12661 aaattctgca cgcggccaat atatcttgcg ccagatcaag aagatcatta agatttcgca
    12721 cgccaaatca tgaatgtctt agacttcgag tatcaaacat aaaacacgcc acaaaaatat
    12781 aacgcgtcag actacaaaga tcacgaatat tccttacgta ccaccaagaa catcctatac
    12841 aaaaaatacc aagaccattt atttgcaaca aacaaacaag actcacctca catcaataaa
    12901 tcaacacaaa gcaaagccac catccctatt ggtatagtgg cctgagaatt ttaagtattc
    12961 aattcgctta aattattttg cgaaaatgtc gataattgct ttgatgattt taatgatagt
    13021 acctacaata gccatcgttt tgtcctcctg tatgttgatt taacatagtg atgagttgtt
    13081 gattgttaat gtttgagatt agttgttacc taaaaattta ccaagtaaat ctttaaagaa
    13141 tttgaataat tttgctacga attccatgtg aatggccccc ttcaaataag atgttcatat
    13201 ctatgagatt tttataactt acttaccagt gaatttctca attaatcctt taatgaattt
    13261 aatgattcct gcaatgatac ccatgtgaaa gacctccttt gtttgttatg aaatcttatt
    13321 taccagtgaa ttgttcgatt aagcttttga taactttaat gatgccagcg atgataccca
    13381 ttaagattac ctcctttgct tatgagttaa cttcattgta catagttatc ttgtgcgtaa
    13441 ttgatttttt tcctaacttg aattgttatg atcataactg cgaatttttt attttaaaag
    13501 gacgggaaat actgcctaac tgtacaggtg cgtttacaaa atctttacaa tcattggttt
    13561 aatagaggtt aagctcatga atttgacatg aagcagaaat ttaattatat tttatgttat
    13621 aagtttaaaa cgaataacac gttaggtctc gtctaggcaa agcatattta tgaagatgaa
    13681 ttgaacagac agaagtaaca ttttatatac atatgtgcat gggagcacgc ttaaagagaa
    13741 cactgcaaca aggtatatca acgtaccgtg atgcagtgtc tagttaaact gaaacctgca
    13801 atagtaaatt ttctgccatt atgtacagaa tctactattg taggttttta tttttataca
    13861 taagcaatta tgcgagagat tagaaataag gaggttatgc agtgttaagt tttcaattgc
    13921 tattttcact gtttgttatt gcgcttatca ttgcattgat aagtggcttg ttgtttttag
    13981 caccagttat gccaatgaga tatattaaat tacatttata catactagtc atgccagtat
    14041 tatttgcagt cattggcttt ttcggtattc atggtcaaca tgtcttaggt ccatttaaaa
    14101 tagatcgttt atcttggtta ttagctggct ttgtaatggc gcttggtttt attattcaaa
    14161 agttttcaat gcgatattta ctaggtgatc atcattatag acattacttt ccattgttca
    14221 ctgcgattac gtcgtttgca tctttagcat ggatgtctga agacttaaga ctgatggcac
    14281 tctgctgggg tatgacatta ttatgtttaa cactgctgat gaacgttaat cgtttttgga
    14341 aagtgccacg tgagtctgcg aaattatcaa gcatgacatt tttatgtggt tggcttgcat
    14401 tcgttggagc aattgtaact atttatattg cgactggtga gtggcgggta ccacaacata
    14461 tagtacatcc gacatggtca ttgttgacga atgtactact tgtattagct gtcatgatac
    14521 cggcagcaca atttcctttt catcgatggt tgattgaatc tgtaacggca ccaacgccag
    14581 tatcggcaat tatgcatgca ggaattgtga atgcaggtgg tgttattcta actcgttttg
    14641 cgccgatatt tgataatgga tttgcgttat cattattact tatcctttct agtatttctg
    14701 tattgttagg atcgggtatt agcttggttc aagttgacta caaaagacag ttagtgggct
    14761 ctacgatgag tcaaatgggc tttatgttag ttcaatgtgc attgggtgta tattcagcag
    14821 cgattattca tttaatattg cacggtattt ttaaagcaac attattttta caatcaggtt
    14881 ctatcgtgaa gcgattcaat attccaaaac aagcatctgc taaagacgct tatggctgga
    14941 ttgtcatggg acgtgtatta gctattatcg tggcatttct attttggatg agtagtgaca
    15001 gaagtgcata tgaagtgtta agtgcactca ttctagcatg gtcattactt gtatcttgga
    15061 atcagatggt agcctttagt aaagggcgca tggcacgtct ggttggcatg attttgattg
    15121 caattgtgac atttatctac gtcatcacac acaattattt ttacgatgta ttacaaaata
    15181 taacaacaca tgcgacaaca ccgcctacag tgagtgtcat cattagtgtt gtcattttaa
    15241 tctttggcag tttattaagt atttgggtgg cgcgtcatcg atactctaag ggttttgcgg
    15301 tattgtacgt gtggttagtt aatctaggtg aagcacgctc gaaagcgata gaaagtcatc
    15361 cgaattattt gaagaagtat ttataggagg tgaaaggtat gacaacacag ttaaatatca
    15421 attcagtcat tgaaaatgcg aaacgtgtta ttacaccatt atcaccgatt tcgatttttg
    15481 cagcacgtaa cccctgggaa ggattagaag cggatacgtt tgaagatgtc gcaaaatggt
    15541 tacgtgacgt tcgcgatgtg gatattttcc caaataaagc attaatagaa agcgctgtgg
    15601 cacgtggtga attagatgaa agtgtcttta atcaacttgt tactgatatg ttacttgaac
    15661 atcactacaa tatcccgcaa cactacatca atctttatat tgataacatt aaaacattaa
    15721 aagacgtacc tgcatcatat atgaatcatt caaatgttga tgttgttgct gatctactat
    15781 tagaaaaatc aaaacgtgat atggctgaat catatcatca ctatgatgta cgtccgatga
    15841 gtgatgcaat aatagatgaa caaggtgagc cacttagcga acaagtgaat cgtcaaatga
    15901 ttaaatggac gaaactttat atcgatcaat ttctatcgag ttggacaatg ccgaagcgtg
    15961 agcaaagttt ttaccatgca tggttgcatt tagcgcaaca tgaccatagt tttactaaag
    16021 cacagcgcca agtgattaaa ggcttaccca atgatcctga aatgacgata gagtcagtat
    16081 taacttattt ttcaatagat caggaagact accaagctta tgttgaagga catcttttgg
    16141 cgttaccggg ttgggcaggt atgttgtatt accgttcaca acagcatcac tttgaacaac
    16201 atttgttaac ggattatttg gcaattcggt tagttgtcga acaattgcta gttggtgatg
    16261 agtttaagtc agtcactaaa gattgtgaaa gtagatcgga aaattggttt aagcaaactg
    16321 ttgcatcatt gtgttactac agtgatatgc ctagcgatgt attactacaa catgacgtca
    16381 atgaaattca aacgtttatt cattttgcag caactatgaa taaaaatgta tttaaaaatt
    16441 tatggctaat tgcctgggaa atgacatacg aatctcagtt aaaacaaaaa attaaagcag
    16501 gtcatgaaag tgtggcgggc gcattagatg taaaccaagt aaatgtctca gaaaatgata
    16561 acgctaatca gccacattca gtattgttaa atgacacaca agcagttgat gaaaataata
    16621 gcgagctaaa tcaggtgggc acatcaacga aagcgcaaat tgcattttgt atagatgttc
    16681 gttcagaacc atttcgtaga catatcgaag cagcagggcc ctttgaaacg attggtattg
    16741 caggtttctt tggattacct attcaaaaag atgccgtaga cgaacaattc aaacatgatt
    16801 cattacctgt catggtaccg ccggcatatc gcattaaaga atttgcagac cgctacgata
    16861 tgaatgttta tcgacaacag caacagacaa tgtcatcgat gttttacaca tttaaattga
    16921 tgaaaaataa tgttatgcct agtctgttat tgcctgaatt aagtgggcca tttttaagct
    16981 tgagtaccat tgtcaattcg attatgccta gaaaaagtcg cgcgtcttta caaaaaataa
    17041 aacaaaaatg gttgaaaaag cctgaaacaa agttaacgat tgatcgtgag tttgaccgaa
    17101 catcagactt acctgttgga tttactgagc aagagcaaat tgatttcgcg ttacaagcgt
    17161 tgaaattgat ggatttaacc gaagcatttg cgccgttcgt tgtgttagca ggtcatgcta
    17221 gtcattctca caataatcca catcatgcat cacttgaatg tggggcttgt ggtggcgcat
    17281 caagcggttt taatgctaag ttattagcga tgatatgtaa tcgtccaaat gtcagacaag
    17341 gattaaaaca atcaggtgtg tatattccag agacaactgt ttttgcggca gcagaacatc
    17401 atacgtctac tgatacgttg gcatgggtat atgtgccaga cacattatca gctttagctc
    17461 tagatgcata tgaatcattg aatgacgcga tgccgatgat ttctgaacaa gcgaatcgcg
    17521 aacgtttgga caaactgcca acgattggtc gtgtgaatca tccagtggaa gaagcacagc
    17581 ggtttgcaag tgattggagt gaggtacgtc cagaatgggg cttggctaaa aatgcatcat
    17641 ttataattgg acgacgccaa ttaacaaaag gcattgattt agaagggcgg acatttttac
    17701 acaattatga ttggcgtaaa gataaagatg gcaaattgtt aaataccatc atttctggtc
    17761 cggcgcttgt ggcacaatgg attaatttac aatattatgc gtcgacagtt gcgccgcatt
    17821 tttacggaag tgggaataaa gcgacacaaa ccgtcacgtc aggtgttggt gtcatgcaag
    17881 gtaatgcgag tgatctgatg tatggcttat catggcaatc tgttatggct gctgatcgga
    17941 cgatgtatca ttcgccaatt cgtttacttg tcgttattca ggcacccgac tatgttgtag
    18001 ctagactatt cgcgaataat gagcatttcg ctaggaaggt gtctaatcat tggctgcgtt
    18061 taatgagcgt taatgaggaa gggcgtttta aaagttggat ttaacgatga tatgttgcga
    18121 tgctaagtaa ttaatatatc atcatatcta caatgttcta gcttcttaaa atatactaaa
    18181 aatgataaac ttaatgtaat agttgatgtc gtgataacga tacaaagatg aagtaatcaa
    18241 ttttaatatt attggagtta gtgatatgaa aagaacgaaa ggtgaaatcg aagctgaaat
    18301 cagtaaagcc attacgcaat gggaaaaaga tttccttggc agaggttcct tgtcagttaa
    18361 atcagacatt ttaagagata tggtgattat tagtttacaa ggtatcttaa cgccagcaga
    18421 atatcgtgtg tgtagtacga atgaaggatt actaaatatt aaacgaacac gttctgaatt
    18481 agttgaatcc ggtgagcaag atttgaatga tatcattctt aaaattacag gtatcaaagt
    18541 gatgagcttc cacagtgatt taagtacagt tacaggtgaa cgtattatcg tattcaaact
    18601 tgaggataat ttggaaaagc atatttaaga aggttaggta tgcttctgct ggcttattaa
    18661 agctatagaa gtatgcttgg ttaaacagcg caacgccata tatttgggtg tgctgttttt
    18721 ctattacatg atgtgtttat tacgtggatg aatgcgtggg tctgaatata gcccgtgaaa
    18781 ggcgtatgtc ataaaatttg cgaatggtga caagtcaacg caagcatatt tgttgcgaga
    18841 catgcccact atccttttac ataaagagta tatgtgtgac gtaggcatat aatcgataaa
    18901 gtatacctaa aaaattaggt ataatgacca ttgttgcaat aagtttttcg gccttgaaac
    18961 cgataacgca tagtataata ggaataaaat ataatacaaa tatccagtaa atcaaatttg
    19021 aaaacgatgg atgaataggg gtaaagaatc taactaatgt aatgattaac gctatataga
    19081 caaaaataac tctattgata cgccttaccc cctctgtata ataaatatag atcgtactaa
    19141 attgaaaata gcaaaatatt gttatttcaa ttatacaatg ttttatttgc aatatacata
    19201 acaatatgaa ctttataatt ttgatattgt cggtaaagtg aaatttgtgg cacattgata
    19261 ttatggataa catttgtaaa atgaaaatga tgatacgagg agattgtaag atgatagata
    19321 aaaaattaac atcaccgaaa atgacagtgc ctttattttt aatcgcgctg attgtattta
    19381 taggtatgtt ttacggtgta gtgacaaatc aagaatggct taaaaatata gatatgggat
    19441 cattaacatg gtttacagat tatttcggtg agccacaacg tcagtatgtt aacaatttgt
    19501 ttaattatta tatgacgttt agtgcggaaa ttggagatgt caaaggtgtc gtgttgattt
    19561 caattatcgt cacaatcata ctgtttatta aacagaggca tttagcggtt tggtttgtga
    19621 catatttggt ttcaggtgtc atcatgaaca aattaattaa agatactgtt ttacgtccaa
    19681 gaccatataa tcatttagcc gttgatacag gcttttcatt tccaagtgga cattccaacg
    19741 ccagcacatt attatatttc gccttaatga tcattattat ttcagttgct gctaagacaa
    19801 taacaaaagt gttgagtgcg ctagttatgg gaatattatg gcttagcata ttattttgtc
    19861 gcctttattt tcatgcacat tacttttcag atgtcattgg cggcacgtca ctagcaatca
    19921 tttgggtagc gttattctta atggtatacc catactttat taatcatcga cgacaacgcg
    19981 tttagcaaac atctttagac atagtggagg tatatagaaa aatgagaatt aaaacaccga
    20041 gtccatctta tttaaaaggc acaaatggac atgcgatatt attattacat tcatttacag
    20101 gtacaaatcg ggatgtgaag catcttgcag ctgagttaaa tgaccaagga tttagttgtt
    20161 atgcaccgaa ttatccaggt catggtttac tgttgaaaga tttcatgaca tataatgtag
    20221 atgattggtg ggaagaagtt gagaaagctt accaattttt agtcaatgaa ggttatgaat
    20281 ctatcagtgc aacgggtgtg tctttaggtg gattaatgac attaaaattg gcgcagcact
    20341 acccgttgaa acgtatcgct gtcatgtcag caccaaagga aaaaagtgat gatggcttaa
    20401 tagaacattt agtttattat agtcaacgca tgtcgaatat tttaaattta gatcagcaag
    20461 catcgagtgc gcaattagca gcaattgatg attatgaagg tgaaattacg aagtttcagc
    20521 attttattga tgatatcatg acaaatttaa atgttattaa aattccagct aatatattat
    20581 ttggtggtaa agatgagcca tcctatgaaa caagtgcaca ttttatttat gaacatttag
    20641 gatcagtaga caaagaatta aatggtctga aggattcgca tcatttaatg acacatggag
    20701 aaggcagaga tattttagaa gaaaatgtta ttcgcttttt caatgcttta acataattga
    20761 agattttaaa tattaacact tgagtgacga tgttattata tttgtcattt gagtgttttt
    20821 tgtggcgtga tagtataggg aacttagaca aagttaattt gtagtgtgat gtcgtggaaa
    20881 tattatgggc attgtacctg aagttgttat gtggcgagat attggcgcac gtatacagcg
    20941 ttgaaccaga aattttaatg tagcgtaatg acaacacatt acaagagttg actatattat
    21001 gataaataca ggcgctaccg tattaatgaa acaattttga tgcaggtgta ttgcatgtta
    21061 tttacataca tgttagagtg ttacttaaac acgtagacgc tttaacgctt taaaggagat
    21121 gtgaatgatg aaaagacaac aatcacaatg gaagtcatca actggattta ttttagctag
    21181 tgcgggttct gcaatcggtc ttggtgccat gtggaaattc ccatatatgg cagggattta
    21241 tggcggcggt gcctttctag ctatgttctt aatattcacc atttttgttg ggttgccatt
    21301 actcattatg gaattcactg ttgggaaaat gggacggaca tatacaacac aaatatatag
    21361 taaattaact ggtaaaaaat ggctcaatat cattggctgg aacggtaatt tggccgtgtt
    21421 tattttattt ggcttctata gtgttatcgg tggttggatt gtcatttaca tcggacaagt
    21481 attatggcaa ttagttatat ttcaacgcat caatcatctc caagaaatga attttgaagc
    21541 ggtaatatca aatccttggt taactgttct agggcaaggt atattcatat tcgctacgat
    21601 gattattgtc atgttaggtg ttgaaaaagg attagaaaag gcatcgaaag ttatgatgcc
    21661 attgctgttt gtctttttaa tcatcattgt gattaagtct ttaacattag atggtgcctt
    21721 agaaggtgtg aaatttattt tacaaccaag agtatcagag attactgctg atggcatctt
    21781 gtttgcgcta ggtcaatcat tctttacgtt atcattagga actacaggta tgattactta
    21841 tgcgagttat gcctctaaag acatgacgat taagtcatca gctatttcta tcgttgttat
    21901 gaatatcttt gtatctgtat tggcaggcct agctatattt ccggcgttac atagttttgg
    21961 ctatgaacca caagaagggc ctggattatt atttaaagta ctgccaatgg tctttagtca
    22021 aatgcatcta ggcacattat tctatttggg attcttagtg ctgttcttat ttgcggcttt
    22081 aacgtcatct atttctttat tagaattaaa tgtttctaac ttcacgaaga atgacaatac
    22141 aaaacgtaaa aaagtcgcag tgatcggtag tattttagta tttatcatta gtattccagc
    22201 aaccttatct tttggtatct taaaagatgt aagattcggt gcgggaacga tttttgataa
    22261 tatggatttc atcgtttcga atgtattgat gccattaggc gcattaggta ctacgcttgt
    22321 cataggacaa ttattagata aaaaattatt acaacaatat tttggtaaag atcgatttag
    22381 attattcaat ggttggtatt acttaattaa gtatgcgatg cctgtcgtta ttattttagt
    22441 ctttatcgtg caattattta gttaatatat agaagcatct gacacacaag tatttgtgtt
    22501 gctcaggtgt ttttttgttt ggaattgaaa agttagtact ggttctgaat taatcgaaac
    22561 ttagataatt gcaaaataac aaaatgtcgt ttataattct tatctgaaaa gtaagaatta
    22621 aaattgagac atgaagaaag gtttcattca tttgatcggc atgtcagatg agggtgcatc
    22681 tatgattact tatgatttaa ttggcaatac accattagta ctgttagaac attatagtga
    22741 tgataaagtt aaaatttatg ccaagcttga acaatggaat cctggaggca gtgttaaaga
    22801 cagactcggg aaatatttag tagagaaggc aattcaagaa gggcgtgtgc gtgcaggtca
    22861 aactattgtt gaagcgactg ctggtaatac aggcataggg ttagctattg cagcgaatag
    22921 acatcatttg aaatgtaaga tctttgcgcc gtatggtttt tcagaagaaa agattaatat
    22981 tatgatagcg cttggtgcag atgtttcaag gacgagtcag tctgaaggta tgcatggggc
    23041 acaattagct gcacgttcct atgctgaaaa atatggtgcc gtttatatga atcaatttga
    23101 atccgaacat aatccggata catattttca tacattggga cccgaattga cttcagcatt
    23161 acagcaaatt gattattttg tggctggtat tggctctggc ggtacattta caggtaccgc
    23221 acgttattta aagcaacatc acgtgcaatg ttatgccgtt gagccagaag ggtccgtgtt
    23281 aaatggaggg ccagctcatg cacatgacac tgaaggtatc ggttctgaga aatggccgat
    23341 atttttagag agacgtcttg tagatgggat atttacgatt aaagatcaag atgcctttcg
    23401 aaatgtcaaa agtttggcta taaatgaagg gttgttagta ggcagttctt caggtgcagc
    23461 attacaaggt gcattgaatt taaaagcgca attatctgaa ggtacgattg ttgtcgtatt
    23521 tccagatggt agcgatcgat atatgtctaa gcaaatattt aattatgagg agaatgatta
    23581 tgaataagaa aactaaatta attcacggtg gacacacaac ggacgactat acaggtgcag
    23641 ttactacacc aatttatcaa acaagtacat atttacaaga tgatattggt gatttacgtc
    23701 aaggatatga atattctcgt actgcgaatc caacaagaag ttctgtagaa agcgttattg
    23761 cggcattaga aaatggcaaa catggctttg cgtttagttc aggtgttgca gctatcagtg
    23821 cagttgttat gctgttggac aaaggtgatc atattatttt aaattcagat gtatacggcg
    23881 gtacttatcg cgcattgaca aaagtattta cacgatttgg cattgaagtg gattttgtag
    23941 atacaacgca tacagattca attgtacaag cgatacgccc aacaacaaag atgttgttta
    24001 ttgaaacacc ttctaatcca ttattacgtg ttactgacat taaaaagtct gctgaaattg
    24061 cgaaagaaca cggtttgatt tcagtcgttg ataacacatt tatgacacct tattatcaga
    24121 atccattaga tttaggcatc gatattgtct tgcattctgc aacgaaatat ttaggtggac
    24181 atagtgatgt cgttgctggt ttagttgcaa catcggatga caagcttgca gaacgtttag
    24241 catttatttc aaattcaaca ggtggcattt taggacctca agatagctat ttacttgtga
    24301 ggggtattaa aacattaggt ttacgtatgg aacaaattaa tcgcagtgtt attgaaatta
    24361 ttaaaatgtt acaagcacat ccagctgtgc aacaagtgtt ccatccaagt attgaaagtc
    24421 atttaaatca tgatgtccat atggctcaag cggatggcca tacaggtgtg attgcatttg
    24481 aagtgaaaaa tacagaaagt gccaaacaat tgattaaagc aacatcgtat tacacattag
    24541 ctgaaagttt aggtgcagtg gaaagtttaa tttcagtacc tgcattgatg acacatgcat
    24601 ccattccagc agatattcga gctaaagaag gtattacaga cggacttgta agaatttctg
    24661 taggtattga agatactgaa gatttagtcg atgatttaaa acaagcacta gatacgctat
    24721 aaataatagc agcactagca tatattttaa gatcaactta aattgatttt gaaaatgcta
    24781 gtgctttttt gtgcgatgtt aatcattcgt gattgagtta tggaggtttg gtggacattt
    24841 gtatggattt aatttgataa atgtcatagt agtctcacaa ttcatcattg tcacatgaat
    24901 taattatttt tttaattttt tagaaaattc ggcaaattgt attgacgata tatgcaattt
    24961 tacatataat gctcttattc ctagtggatt aataagaatt tgtaggaggg gcgatgatga
    25021 ttgagtttcg acaagttagt aaatcatttc ataagaaaaa gcaaacaata gatgctttgt
    25081 aggacgtatc atttacggtc aatcgcaatg atatttttgg tgtgattgga tatagtggtg
    25141 caggaaaaag tacgttggta agactcgtga atcatcttga agctgcctcg aatggacaag
    25201 tgattgtaga tggacatgat attacgaatt atagcgaaaa aggcatgcga gaaattaaga
    25261 aagatatcgg tatgatattt cagcatttca atttattaaa ttcagctacg gtatttaaaa
    25321 atgtagcaat gccactcatt ttaagtaaga aaagcaaaac agaaattaag caacgagtaa
    25381 cggaaatgct tgaatttgta ggattgagtg ataaaaaaga ccaatttcct gatgaattat
    25441 ctggtgggca gaagcaaagg gtggctattg caagagcgct tgttactaat ccgaaaatac
    25501 tcctatgcga tgaagcaaca agcgcattgg atccagcaac gactgcttcg atattgacgt
    25561 tattaaagaa tgtcaatcaa acctttggca ttacaattat gatgattaca catgaaatgc
    25621 gcgttattaa agacatttgt aatcgtgttg ctgtaatgga aaaggggcaa gtggttgaaa
    25681 caggaactgt taaagaggtg tttagtcatc ctaaaacgac gattgctcaa aattttgtgt
    25741 ctacagttat acagactgag ccaagtacat cattgattcg tcgattgaat gacgaacaag
    25801 ttggcggttt taaagattat aaaatcttcg tcgaggaaac tcaggtgaca caaccgatta
    25861 taaatgactt gattcaaatt tgtggcagag aggttaaaat tttattttca tctatgtcag
    25921 aaatacaagg taacaccgta tgttatatgt ggcttcgatt taatatagat caacaatttg
    25981 atgacacggc aataaatcaa tatttcaaag agaaaaatat tcaatttgag gaggtgcatt
    26041 aacatatgtt tggttctgat ttagacagtg cacagttatt acaagcattg tacgaaacgt
    26101 tatatatggt atctattgct ttatttttag gagcagtgat tggtattcca ttaggtgtct
    26161 tattggtaat tactcgaaaa caaggcatat ggcccaatat agtgatacat caagttttaa
    26221 atcctttaat caatatttta aggtcactac catttattat tttgttaatt gcgattgtgc
    26281 cattcacaaa attagtagta ggtacttcaa ttggtacgac tgctgccatc gtgcctttaa
    26341 ctgtatatgt ggcaccttac attgcaagac ttgttgaaaa ctcattattg gaagtagacg
    26401 aggggattat tgaagcggcg aaagcgatgg gcgcttcacc actacaaatc attagatatt
    26461 ttttaattcc tgaagcgtta ggttcattag tattagcaat taccactgcg attattggac
    26521 ttattggaag tacggcgatg gcaggagctg ttggcggtgg tggtatagga gacttagctt
    26581 tagtgtatgg ttatcaaaga tttgatacga cggtcattat tattaccgtt attgtattag
    26641 tcattattgt ccaagtgatt caaacgctag ggaatgtcct agctagattc atacgtagac
    26701 attaatgata tatagtgaag attttgaaag gaattgatag aatgaaaaga ttgattgggt
    26761 tagttatcgt agcacttgta ttattagcag cgtgtggtag taacaatgat aaaaaagtaa
    26821 caattggtgt cgcatcaaat gacactaagg cttgggagaa ggttaaagaa ttagctaaaa
    26881 aagatgatat tgatgtggag attaagcact tctccgatta caatttaccg aataaagcat
    26941 taaacgatgg tgatattgat atgaatgcat tccaacattt tgcattttta gatcagtata
    27001 agaaggcaca taaaggaaca aagatttcag cattgagtac aacagtttta gcaccgttgg
    27061 gcatttactc agataaaatt aaagatgtca aaaaggttaa agatggtgct aaagttgtca
    27121 ttccaaatga tgtatcaaac caagcacgtg cacttaaact attagaagca gctggtttaa
    27181 taaaactgaa aaaagatttc ggattagcag gtacagtgaa agatataacg tcaaatccaa
    27241 aacatttaaa aattactgca gtagatgcac aacaaactgc gcgtgcttta tctgatgtcg
    27301 atattgcagt tattaataat ggtgtagcaa ctaaagcggg taaagatcct aaaaatgatc
    27361 cgatattttt agaaaaatca aattcagatg ctgtaaagcc atatattaat attgttgcag
    27421 ttaatgacaa agacttggat aacaaaacat atgctaaaat cgtagaattg tatcattcaa
    27481 aagaagctca aaaagcgttg caggaagatg tcaaagatgg agagaaacct gttaatttat
    27541 ctaaagatga gattaaggca atagaaacgt cattagcaaa ataaattata ttgcgtccta
    27601 caagcaaagt tcatgcttat gtttgtaggg cgttattgtt tgacaataaa attatttcca
    27661 atagagaaag ggaatgtaat cattttatag tgaaatatta tgaaattgta ataatttaga
    27721 tattgtaaaa tctaataagt tgtaataatt ttaaggggta attataaaat ttgatgatac
    27781 agtatatgat ttttttgtaa tcataatgtc atcaaacatc aacctattat acataataaa
    27841 atcgtataat gatgtagtat tcataaattc ggataaaaga atgttaggaa agttaagcaa
    27901 gaggaggatt ttaaagtgca aaaaaaagta attgcagcta ttattgggac aagcgcgatt
    27961 agcgctgttg cggcaactca agcaaatgcg gctacaactc acacagtaaa accgggtgaa
    28021 tcagtgtggg caatttcaaa taagtatggg atttcgattg ctaaattaaa gtcattaaac
    28081 aatttaacat ctaatctaat tttcccaaac caagtactaa aagtatctgg ctcaagtaat
    28141 tctacgagta atagtagccg tccatcaacg aactcaggtg gcggatcata ctacacagta
    28201 caagcaggcg actcattatc attaatcgca tcaaaatatg gtacaactta ccaaaacatt
    28261 atgcgactta atggtttaaa taatttcttt atttatccag gtcaaaaatt aaaagtatca
    28321 ggtactgcta gctcaagtaa cgctgcgagc aatagtagcc gtccatcaac gaactcaggc
    28381 ggtggatcat actacacagt acaagcaggt gactcattgt cattaatcgc atcaaaatat
    28441 ggtacaactt atcaaaaaat tatgagctta aatggcttaa ataatttctt tatttatccg
    28501 ggtcaaaaat tgaaagtaac tggtaatgca tctacgaact caggatctgc aacaactacg
    28561 aatagaggtt acaatacacc agtattcagt caccaaaact tatatacatg gggtcaatgt
    28621 acatatcatg tatttaatcg tcgtgctgaa attggtaaag gtattagtac ttattggtgg
    28681 aatgctaata actgggataa cgcagcggca gcagatggtt acactatcga caatagacct
    28741 actgtaggtt ctatcgctca aacagatgta ggttattatg gtcatgttat gtttgtagaa
    28801 cgtgtaaata acgatggtag tattttagtt tcagaaatga actattcagc tgcaccaggt
    28861 attttaactt acagaacggt accagcttac caagtaaata attatagata tattcactaa
    28921 agtcttacgt atataaatat ataatgaatt cctattacat ttcacaagct gaaaagttgg
    28981 attgaatcct aaactttatg gcggggctat caaagtcgtg attgttgtaa taggaatttt
    29041 tgtataagaa aaaggattgg tcgaatgaac ttcatgttct atgttcgacc aatccttttc
    29101 tgaattagta ttcatgcttt actttgcgaa tgcttgtaaa taatctagca ccgtttgtta
    29161 ttaaagtaac aactgccact gcttttttga acttacgtgg tgacttaatt gaaatgtaaa
    29221 agtctaacac ggttcctaca gtgcttaaac ctaatgaaag atatactaat tttttatttt
    29281 tagcatgata tttatagcca ttgtagccgt cgactatgaa acctgcgaca tttagtaaac
    29341 ttgataaacg ttgtgatttg gaacgttttg ccataataat aattccccct agtatcttct
    29401 gtttatatga aaagttgggt gcgctgaatt gctaacgttt tgcgctataa ctactcatat
    29461 atgataacat aattgtacag tataatttga aaaattgatt tcacaaagtt ggggtgtcaa
    29521 agatgattaa atgtgtctgt ttagttgaag aaacagctga taaaatattg cttgttcaag
    29581 taaggaatcg cgaaaagtat tatttcccag gtggtaaaat agaagaagga gaatcacaag
    29641 tacacgcgct gttaagagaa gtaaaagaag aattaaattt aacattaaca atggatgaaa
    29701 ttgaatatat cgggacaatt gtaggtcctg catatccaca acaggatatg ttaactgagt
    29761 taaatggatt tcgcgcatta accaaaatcg attgggaaaa cgtaactatc aataatgaaa
    29821 ttacggatat acgctggatt gataaagata atgatgcgtt gattgcgcct gctgtcaaag
    29881 tttggattga aacgtatggt ggtaaacatg acaaataatg acaccatcat gttacgacat
    29941 tatgtcccac aagattattc gatgttagaa gcttttcaat taagtgaaag tgatttgaag
    30001 tttgttaaaa cgccagagga aaatattaca gctgcaatgt ctgataatga aaggtatccc
    30061 atcgttgtaa tggatggcag gcaatgtgtg gcctttttta cattacatcg tggaaaaggg
    30121 gtcgcaccat ttagcgataa ccaagatgca gtatttttca ggtcatttag tgttgatcaa
    30181 cgttatcgta atagaggaat aggtaaagtg gtaatggaaa aattggcgtc atttatcact
    30241 tcaacatttc aggatattaa tgagattgtg ttaacggtta atactgacaa tccacatgcc
    30301 atggcacttt atcgccaaca aggatatcaa tatatgggag atagtatgtt catcggaaga
    30361 cctgttcata ttatggcgtt aactataaaa taaattaaat ttaaaagcat ctttactcat
    30421 cgtcgaccac aacaattaat gatgaataaa ggtgcttttt gttatagatc accggacaat
    30481 ttaatatagt aaaaagcgac ctagtgaaca attgacatat atccacaggt cgcttaactt
    30541 aagttatatt gctagttgcg attaattgat agactcatca tttttgcgct gtcgagatgg
    30601 tctttttatt aaaaatgccg taatccaagc cgtaatcgga atactgattg caacggcaat
    30661 accgcctaaa ataatagaaa taaattcctg ggcaaatatt ttcgagttta taatatgacc
    30721 aaatgaatat ttaagtttga aaaaccaaat aaataaagca agttggccac caaaaaaggc
    30781 aaggtaaatc gtgttcgcag atgtcgctaa aatttctcta ccaacacgca tgccagattg
    30841 gaataattcg tattgcgtaa gtgttggatt tacttgatgc aattcataaa tgggtgaact
    30901 aatggtaatc gttaaatcta tcacagctgc aataacagca agaataatag tgaacaccat
    30961 aaattgaacc atatcaatgc caatattcat tgaatacaca tatgtttcat cttgttgttc
    31021 ggttgaaaag ccttgtagat gaccgaagta gacagataaa taaatgagtg taatcaacaa
    31081 tattgttgta acgatagtgc tgataaatgc agcttgtgtt ttaacattgt aactattgag
    31141 tacgaataaa ttacaagcgc caataataat gcagaaaaag aatgtgacga cataaatcgg
    31201 tacgccaaaa ataatcaata caatactaat aattaaaata gcgaaattta aaaatagggt
    31261 taaataagag atgaatccct ttttacctcc gaaaattatc atcagaaaga ggagcaataa
    31321 cgccaatata aatacagcat tcattgtttc gccctcctta atgtttcaaa tatttccata
    31381 aacaatattg tgataggaat tgtaagtacg atacctatac cgcctgttag tgcgcgcgca
    31441 atttctaacg accaattcat cgaaatagta taagtcacag tatttgcatt ttttaaaaag
    31501 attaaaaaca taggtagtgc accggataaa tatgagaata ataagatgtt agtcattgtt
    31561 cccataatat cttggccgat gtttcgccca gcaagcgccc atctcctcat tgaaatgtgt
    31621 ggcgtacgct gtaaaatttc atgcatacca ctagcaattg taattgcaac atccataata
    31681 gcgccaagtg aacctattaa cactgaggct aggaagatat ctttcggtgg taatgataaa
    31741 aagttcatcg tttcatattt aatgccttta ccatctgtca tatatatgat taattctgtt
    31801 aaacctatac tcaaaaaagt tccgataatt gtactggcta tggtaatgag tgtacgcata
    31861 tgccagcctg taacgagcaa taaagtgagt attgttgaac agatcatggc aatggtcatg
    31921 agtaagaata aattaatatt gctatgttga atatgaatgt aaattgcgat taatatggca
    31981 atagaattca agattaacga taaaatcgat tgcagtccga ctttgcgacc aaccaataat
    32041 acagttaata agaacaaacc agtgatgata accgttaagg tatcacgctt cttttctata
    32101 atataagcat cactcggctt gttagaaata tgtaataata ctttttcgtg tgtgcgaaat
    32161 gcctcagaat ctgcttgcga tttgacgtac tgatgattaa tcgtcgtcgt ttctccagca
    32221 aattgaccat ttaatatttt gacttttaat tgatttttat atttaatatc acgattattt
    32281 tgtgcatctt ttgtaggtgt cgaagaaaca tgtttgacat ctataatttg accaattggt
    32341 ttgttgtaaa agttctcatt attgaatgta aataaaatag caccaatgaa tgcgatgcag
    32401 aacaaaccta aaattatatt aaatggcttt gtaaataaat ttctatattt caaaaacaaa
    32461 accccaattc tatgaatgaa ttaatatggt gattatacgc ccttaatttt ttattttcaa
    32521 agatattact gctaagtgta aaacgaaaat catcattgat agcatcgaat tacttaatgg
    32581 aatgtagacg ttttagtcat taattgctga ataagtgtta ataatatgcc aatatcactc
    32641 tttgtataag gctcctttgt aatagcacat atcgttcttt ttaattcagt atgatctaat
    32701 tttatatcta tccatgattt agattctggt aaatgtatat tttgtgatga aatgatgtaa
    32761 ccttcttttt gacgaaggag atactgcgca agtggttggc tactgattgt gtatacatct
    32821 gatttagtaa tcttgcgcaa ttgttttttt acagtttcgg caaatggtgc caagcaataa
    32881 atatgactat gctcaaactg aattaatggt gggtgtgtcg ccatcgtaat tggatcgtct
    32941 gaaggcgcat ataaatgata gtgctcttcg aataaaggta gcatatgtaa ttgtttgtgt
    33001 ttacgtattt ctggtgtaag ttccgtgaaa ccaatgtcta tattcccatt taatacgcta
    33061 tttataatcg tgtcatgatc taataagctc ggtatgacat gtgtatcatt ttgtaaatga
    33121 aacgtttgga taagtggtag taacatgtgg gatacgtcac tctcatcata gccaatgtag
    33181 atacttttat ttttagttaa tccatggctt tgaaattgtt caatcgtgct atctaaatgt
    33241 tcaataatac gcagagcttc attaaataat aatttccctt cagatgtgag cgtaatattg
    33301 cgtccttgct ttttaaataa agacacatta agttcttgtt ctaataatgt aatttgacgg
    33361 cttatcgctg attgagcaat gtttagttca agtgctgttt cggagatatg ttctctttta
    33421 gcgacctcga taaaatatct taattgttta atttccatag cgatataggc acctccgaaa
    33481 atgagtgttt tgtaactatt atagcaatat tattgataaa tgttctattt tttagatgaa
    33541 tatcttctat tttatatatt gaacagataa attttttaga ttatagtaat tatcattaat
    33601 aactaatatc agaatattct aaaaaagggg tgtgcatcat gcacaatgag aaattaatta
    33661 aaggcttata tgactatcgt gaggaacatg atgcgtgtgg tattggtttt tatgcgaata
    33721 tggataataa aaggtctcac gacatcattg ataaatcgct tgaaatgttg cgacgcttag
    33781 atcacagggg cggggtcggc gcagatggca tcactggtga tggcgcaggt attatgactg
    33841 aaataccttt tgcatttttc aaacaacatg taacggactt tgatatccca ggtgaaggtg
    33901 aatatgccgt ggggttattt ttttccaaag aacgcatttt aggttctgaa catgaagcag
    33961 tttttaaaaa atattttgaa ggcgaagggt tatcaattct tggttatcgt aatgtaccag
    34021 ttaataaaga tgccattgct aaacatgtag cagatacgat gccagtcatt caacaagtgt
    34081 ttattgatat taggggcatt gaagatgttg aaaagcgttt gtttttagcg agaaaacaat
    34141 tagagttcta ttcgactcag tgcgatttag aattgtattt tacgagctta tcacgcaaaa
    34201 caattgtata taaaggttgg ttacgatcag accaaattaa aaaactatat acagatttat
    34261 cggatgattt atatcaatca aagctagggt tagtgcattc gagatttagt acgaatacat
    34321 tcccgagttg gaaaagggca catcctaacc gtatgttaat gcataatggt gagattaaca
    34381 cgattaaagg taatgtaaac tggatgcgag cacgccaaca taaattaatc gaaacattat
    34441 ttggcgagga tcaacataaa gtgtttcaaa ttgtcgatga ggatggtagt gactctgcta
    34501 ttgtagataa tgcgctagag ttcttatcgt tagccatgga gccagaaaag gcagcgatgc
    34561 tactcatacc tgaaccttgg ttatacaatg aagcgaatga tgcaaatgta cgtgcgtttt
    34621 atgaatttta tagttattta atggaaccgt gggatggtcc tacaatgatt tcgttctgta
    34681 acggtgacaa acttggcgcg cttacagata gaaatggatt acgtccaggt cgttatacga
    34741 ttactaaaga taactttatt gtcttttcat ctgaagtggg tgttgtggac gtacctgaaa
    34801 gtaatgttgc ttttaaaggt caattgaatc ctggaaagtt attgcttgtt gattttaaac
    34861 agaataaagt cattgaaaat aatgatttaa aaggtgcgat tgctggagaa ttaccatata
    34921 aagcgtggat tgataaccat aaagttgact ttgattttga aaatatacaa tatcaagatt
    34981 cgcaatggaa agatgagacg ttatttaaat tacaacgtca gtttgcatac acgaaagaag
    35041 agattcataa gtatattcag gaacttgtag aaggtaagaa ggatcctatc ggtgcaatgg
    35101 gatatgatgc gccaattgca gtgttgaacg agcgaccaga atcactattt aattacttta
    35161 aacagctgtt tgcacaagtt acgaatccac caattgatgc gtatcgtgaa aaaatcgtaa
    35221 cgagtgaact ttcttattta ggtggcgaag gtaacttact agcacctgac gaaacggttt
    35281 tagatcgtat tcaattgaaa aggccggtat tgaatgaatc acacttagca gcgattgatc
    35341 aggaacattt taaattaact tatttatcaa cggtatatga aggggatttg gaagatgcgt
    35401 tagaagcatt aggccgagaa gcagtgaatg ctgtaaagca aggcgctcaa attctagtgt
    35461 tagatgacag tggattagtt gatagcaatg gctttgcaat gccgatgtta ctcgcaataa
    35521 gtcatgtgca tcaattactt attaaagcag atttacgtat gtctacaagt ttagtcgcta
    35581 aatctggtga gacacgagaa gtgcatcatg ttgcttgttt actcgcatat ggcgcgaatg
    35641 caattgtgcc atacctagcg caacgtacag ttgaacaact gacattgaca gaagggttac
    35701 aaggcaccgt tgtcgataat gttaagacat atacggatgt attgtcagaa ggtgtcatta
    35761 aagtaatggc taagatggga atttcgacag tgcaaagtta tcaaggtgca caaatatttg
    35821 aagcgattgg cttgtctcat gatgtgattg atcgttattt tactgggaca cagtctaagt
    35881 tatcgggtat ttcgattgat caaattgatg ctgaaaataa agcacgtcaa caaagtgatg
    35941 ataattatct tgcatcaggt agtacatttc aatggagaca acaaggtcaa catcatgctt
    36001 ttaatccgga atctattttc ttattgcagc acgcatgtaa agaaaatgac tatgcgcaat
    36061 ttaaagcata ctctgaagcg gtgaacaaaa atagaacaga tcacattaga catttacttg
    36121 aatttaaagc atgtacaccg attgacatcg accaagttga accggtaagt gacattgtca
    36181 aacgctttaa tacaggggcg atgagttatg gatcgatttc agcggaagca catgaaacgt
    36241 tagcacaagc catgaaccaa ttaggtggaa agagtaatag tggtgaaggt ggcgaagatg
    36301 caaaacgtta tgaagtacaa gttgatggaa gcaacaaagt aagtgcgatt aaacaagttg
    36361 cttctgggcg ttttggtgta actagtgatt atttacaaca tgccaaagaa attcaaatta
    36421 aagttgcgca aggtgcaaag cctggtgaag gtggtcaatt acctggtact aaggtatatc
    36481 cgtggattgc aaagacaaga gggtcaacgc caggtatcgg tctgatttca ccaccgccac
    36541 atcatgatat ttattcaata gaagatttag cgcaactgat acatgatttg aaaaatgcga
    36601 ataaagatgc agatatcgcg gtaaaattag tttcgaaaac aggtgttggt accattgcat
    36661 ctggggtggc aaaagcattt gcagataaaa ttgtcatcag tggttacgat ggtggtacag
    36721 gggcttcacc taaaacgagt attcagcatg ccggtgttcc ttgggagatt ggtttagcag
    36781 aaacacatca aacattaaaa ctaaatgact taagaagtcg tgttaagtta gaaacagacg
    36841 gtaagttatt aactggtaaa gatgtagcgt acgcatgtgc gcttggagcg gaagaatttg
    36901 gatttgcaac tgcaccatta gtggtgttgg gctgtattat gatgcgtgta tgccataaag
    36961 atacatgtcc agtaggagtt gcaactcaaa acaaagattt acgtgcttta tatagaggta
    37021 aagcacatca tgttgttaat tttatgcatt ttattgcaca agaattaaga gaaattttag
    37081 catctttagg tttgaaacgt gtagaagact tagttggaag aactgattta ttacaacgat
    37141 catcaatatt aaaagcgaat agcaaagcgg ctagtattga tgttgaaaaa ctgttatgtc
    37201 ctttcgatgg gccaaacaca aaagaaattc aacaaaatca taatcttgag catggatttg
    37261 atttaacaaa tttatatgaa gtaacgaagc catatattgc tgaaggacgt cgctatacag
    37321 gtagctttac agtaaataat gaacaacgtg atgtaggagt tattacaggt agtgagattt
    37381 cgaaacaata tggagaagca ggacttcctg aaaatacaat taatgtttat acgaatggtc
    37441 atgctggtca aagtcttgca gcatatgcac cgaaaggctt aatgattcat catactggag
    37501 atgcgaatga ctatgttggt aaaggattat ctggtggtac ggtcattgtc aaagcacctt
    37561 ttgaagaacg acaaaatgaa attattgctg gtaacgtctc attctatggt gcgacaggtg
    37621 gtaaggcatt tattaacggt agtgcaggag aaagattctg tattagaaat agtggtgtag
    37681 atgttgtcgt tgaaggtatc ggtgaccatg gattagagta catgactggt ggacatgtca
    37741 ttaatttagg tgatgtaggt aagaacttcg gtcaaggtat gagtggtggt attgcttacg
    37801 ttatcccgtc tgatgtagaa gcttttgttg aaaataatca actagatacg ctttcgttta
    37861 caaagattaa acaccaagaa gaaaaagcat tcattaagca aatgctggaa gaacatgtgt
    37921 cacacacgaa tagtacgaga gcgattcatg tgttaaaaca ttttgatcgc attgaagatg
    37981 tcgtcgttaa agttattcct aaagattatc aattaatgat gcaaaaaatt catttgcaca
    38041 aatcattaca tgacaatgaa gatgaagcga tgttagctgc attttacgat gacagtaaaa
    38101 caatcgacgc taaacataaa ccagccgttg tgtattaagg aaagggggag atacgatggg
    38161 tgaatttaaa ggatttatga agtatgacaa acagtactta ggtgaattat cactggtaga
    38221 ccgtttgaag catcataaag catatcaaca acgatttact aaagaagatg cctctatcca
    38281 aggtgcgcga tgtatggatt gtggaacgcc gttttgtcaa accggacaac agtatggtag
    38341 ggaaacaata ggttgtccaa ttggaaacta cattcctgaa tggaacgact tagtgtatca
    38401 tcaagatttt aaaactgctt atgaacgctt aagcgaaaca aataactttc ctgactttac
    38461 agggcgtgta tgtcctgcac catgcgaaag tgcttgtgtg atgaagatta atagagaatc
    38521 gattgcgatt aaaggtattg aacgcacaat tattgatgaa gcttttgaaa atggttgggt
    38581 agcgccgaaa gttccgagtc gccgtagaga tgaaaaagtg gcaatcgttg gaagcggtcc
    38641 agcaggatta actgctgctg aagaacttaa tctactagga tatcaagtga ctatttatga
    38701 acgtgctaga gaatcaggcg gtttattaat gtatggtatt ccaaatatga agcttgataa
    38761 agatgtggtt cgacgtcgta ttaagttaat ggaagaagcg ggcattactt tcattaatgg
    38821 tgttgaagta ggcgttgata ttgataaagc aacgttagaa tctgagtatg atgccattat
    38881 attatgtact ggtgcacaaa aaggtagaga tttaccttta gaaggacgca tgggtgatgg
    38941 tatacatttc gctatggatt atttaactga acaaacgcag ctgttaaatg gagaaattga
    39001 tgatattaca ataactgcaa aagataagaa tgtcattatc attggtgctg gtgatacagg
    39061 ggcagactgt gtagcgacag cattaagaga aaattgtaaa tcgattgttc aatttaataa
    39121 atatacgaaa ttgccagaag caattacatt tacagaaaat gcatcatggc ctttagcaat
    39181 gccggtgttt aaaatggact atgcgcacca agagtacgaa gctaagtttg gtaaggaacc
    39241 acgtgcatat ggtgttcaaa caatgcgtta cgatgttgac gataaaggac acatacgtgg
    39301 tttgtatact caaattttag agcaaggcga aaatggtatg gtcatgaaag aaggacctga
    39361 aagattttgg cctgctgacc ttgtattatt atcaatcggc ttcgaaggta cagaaccaac
    39421 agtaccgaat gcttttaaca ttaaaacgga tagaaatcga atcgtggcgg atgatacaaa
    39481 ctatcaaact aataatgaaa aggtatttgc tgctggagat gctagacgtg gtcaaagttt
    39541 agttgtatgg gcaattaaag aaggtagagg cgtagcgaaa gcagtagatc agtatttagc
    39601 gagtaaagtt tgtgtataat ctttgtatgg aaatggtggt tacgttgacg ttgtgtcatg
    39661 ctgaatcgag tttgaaataa tctagtatct atcaacgtca catgccatct ttgtaaccta
    39721 aaaacaaagg tttgtaagac aacaaatcga ttaattataa gtagtgattt tttacattcg
    39781 tttataggtc aactgtagtg gaagacaatg atttgtggta atcatgtaat gcttaaaaac
    39841 aatattgact tttacagaac gttcatatat gataaatatt gtgtttagga ggaataccca
    39901 agtccggctg aagggatcgg tcttgaaaac cgacaggggc ttaacggctc gcgggggttc
    39961 gaatccctct tcctccgcca tcaatattta tattaaatac tatatataat gaaggtaagt
    40021 gctcaaattt tgagtatttg ccttttttat ttgtctttga atggctcgtt tttttagcta
    40081 tagaaatgat agggcattga gattggaagg gcatttggct tgtgcaatat acatagctaa
    40141 atgtcttttt tgttttgtga aatatgatgg atggcttgtg tgggcaagtt tgctatttat
    40201 agatatgcat ttttcaattt aggagttggc catgcatcta cactttataa tggtgagagc
    40261 gtggtgaggt attgttaatc acgcaattgt agcgaggagt tattgctaca tatgtcgtta
    40321 tggcctattg attttctaaa atagctgtat cagatcatgt gacaaaataa aaataatttg
    40381 ttgaaagcct ttacataact tgtctagaca agttatactc gttttaagac attaagggag
    40441 tgaaatatat ggctgtaaaa agagaagatg taaaagccat cgtaagcgct attgggggaa
    40501 aagaaaatct tgaagctgca acgcattgtg taacacgatt acgtttagtg cttaaagatg
    40561 aaagcaaagt tgataaagac gcattaagta ataacgcgtt ggtcaagggg cagttcaaag
    40621 cagaccatca atatcaaatt gtcattggtc caggaacagt cgatgaagtg tataagcagt
    40681 ttattgatga aacaggtgct caagaagctt cgaaagatga agcgaaacaa gcagctgcga
    40741 aaaaagggaa tccagtacaa cgtttgatca aattgttagg ggatattttt ataccaatat
    40801 tacctgcgat tgtgacagct ggtttgttaa tggggatcaa taatttactt acaatgaaag
    40861 gtttatttgg tccaaaagca cttattgaga tgtatccgca aattgctgat atttcaaaca
    40921 tcattaatgt gattgcgagt acggcattta ttttcttacc agcattaatt ggttggagta
    40981 gtatgcgtgt atttggtggt agtccgattc taggcatagt cttaggtttg attttaatgc
    41041 atccgcaatt agtatctcag tatgatttgg caaaagggaa tattccgacg tggaacttat
    41101 ttggcttaga gattaagcag ttgaattacc aaggtcaagt gttgcctgtt ttaattgcag
    41161 cttatgttct agctaaaatt gaaaaaggat taaataaagt cgttcacgat tcgataaaaa
    41221 tgttggtcgt tggacccgta gcgcttttag ttactggatt tttagcattt attatcattg
    41281 gaccagttgc attattgatt ggtacaggta ttacatctgg tgttacattt atattccaac
    41341 atgcaggatg gcttggcgga gcaatatatg gattgttata tgcaccactt gtaattacag
    41401 gactacacca tatgttttta gcagtagatt tccaattgat gggtagcagc ttaggtggta
    41461 cgtatttatg gccaattgtt gcgatttcca atatttgtca gggctctgca gcatttggag
    41521 catggtttgt ctataaacgt cgtaaaatgg ttaaagaaga aggcttggca ttaacatctt
    41581 gtatttctgg tatgttaggt gttactgaac cagctatgtt tggtgtgaac ttacctttga
    41641 aatatccatt tatcgctgcg atatcaacgt cttgtgtatt gggggcaatc gttggtatga
    41701 ataacgtact tggaaaagtt ggtgttggtg gcgtgccagc attcatttca attcaaaaag
    41761 aattttggcc agtatatctt attgtgacag ctattgctat tgttgtacca tgtatactaa
    41821 caattgtgat gtctcatttt agtaaacaaa aagcgaaaga aattgttgaa gattaataaa
    41881 ataaaaaagg ggcgttcgtt atttggacgt cctttattac gttataaggt ggtaattgtg
    41941 tgtcgaaaga aatagattgg agaaaatccg ttgtatatca aatttatcct aagtcgttta
    42001 atgatacgac ggggaatggt ataggagata tcaacggaat tatagaaaaa ttggattata
    42061 tcaagttatt gggtgttgat tatatttggt taacaccagt gtatgaatca cctatgaatg
    42121 ataatggcta tgatatcagc aattatttag aaatcaatga agcctttgga acgatggatg
    42181 attttgaaaa gttaatcaaa gttgctcatc aaaaagactt gaaagtgatg ttagatattg
    42241 ttattaatca tacgtcgacg gagcatgaat ggtttaaaga agcccgtaaa tctaaagata
    42301 acccttatag agattattac tttttcagat catctgaaga cgggccgcca acaaattggc
    42361 attctaaatt cggtggtaat gcatggaagt atgattctga gacagatgaa tattatttac
    42421 atttatttga tgtcagtcaa gctgatttaa attgggataa tccggaagta cgtcaatcgt
    42481 tatatcgcat agtcaatcat tggatagact tcggcgttga tggttttcga tttgatgtca
    42541 ttaacttaat ttctaaaggt gaatttaagg actctgacaa aataggtaaa gaattttata
    42601 cggatggtcc tagagtgcat gagtttctgc atgaattaaa tcgtcaaacg tttggtaaca
    42661 ctgacatgat gactgtagga gaaatgtctt cgacgacgat tgaaaattgt attaagtata
    42721 cacaaccaga acgccaagaa ttgaatagtg tttttaattt tcatcatcta aaggttgatt
    42781 atgttgatgg tgaaaagtgg acaaatgcga agcttgattt tcataagtta aaggaaattc
    42841 tgatgcaatg gcaacgaggt atttatgacg gtggcggatg gaacgcgatt ttctggtgta
    42901 atcatgatca gccacgggta gtgtctagat ttggtgatga tacgtcggaa gagatgagga
    42961 tacaaagtgc taaaatgtta gctatcgcac tgcatatgtt gcaagggacg ccatatattt
    43021 accaaggtga agaaattggt atgacggacc cacattttac atcaatagca caatatcgtg
    43081 atgttgaatc gattaatgcc taccatcagt tgctaagtga agggcatgct gaagcggatg
    43141 tattagcgat tttaggacag aagtcacgag acaattcgag aacgcctatg caatggagtg
    43201 atgatgttaa tgctggattt acagctggta agccttggat tgatatttcg gaaaattatc
    43261 atcaggtcaa cgttagacaa gcacttcaga ataaagagtc tattttctat acgtatcaaa
    43321 aattaataca attaagacat acgcatgata ttattacgta tggagacatt gtgccacgtt
    43381 ttatggatca tgatcattta tttgtttatg aacgtcatta taagaatcaa caatggctag
    43441 taattgcgaa tttctcagca tcggctgttg atttgccaga aggattggct agagaaggtt
    43501 gtgttgtgat tcaaacaggc acagtggaaa ataatacgat aagcgggttt ggtgcaattg
    43561 taatcgaaac aaacgcgtaa aataaattga gtggatgcgt ttatatggcg aaacaaaaaa
    43621 agtttatgaa gatttatgag gcgttgaaag aagatatatt aaacgggcag attcaatatg
    43681 gtgaacaaat tccgtctgaa catgatttgg tgcaattgta ccagtcatct cgagagaccg
    43741 tgcgtaaggc attagatttg ttggcattag acggcatgat tcaaaagatt catggtaaag
    43801 ggtcacttgt catttatcag gaggttacag agtttccatt ttctgaactt gttagtttta
    43861 aagaaatgca agaagaaatg ggcgtcgcat atttaactga agttgttgtg aatgaggttg
    43921 ttgaagcgca tgaagttcca gaagttcaac atgctttaaa catcaattct agtgaatcgc
    43981 tcattcatat tgttagaact cgtcggctta accaacatgt gaagattgtt gatgaagatt
    44041 attttctaaa gtcgattgtt tcagatatag gtaatgatgt tgcgagtgat tctatttatg
    44101 attatttgga aaaggtatta aatcttaata ttagttattc aagtaagtct attacttttg
    44161 aaccgtttga tgaacaagca tatcaattgt ttggtgatgt atcggtggct tattcagcaa
    44221 cagttcgaag tattgtgtat ttagaaaata caatgccgtt tcaatataat atttcaaaac
    44281 atcttgcaaa tgaatttaaa tttaacgact tctcaagacg tcgtataaag taaacaatga
    44341 tataaatgat ttatacttgc aattaactat taaaatatag taatatatat cttgccgtgc
    44401 taggtgggga ggtagcggtt ccctgtactc gaaatccgct ttatgcgagg cttaattcct
    44461 ttgttgaggc cgtatttttg cgaagtctgc ccaaagcacg tagtgtttga agatttcggt
    44521 cctatgcaat atgaacccat gaaccatgtc aggtcctgac ggaagcagca ttaagtggat
    44581 catcatatgt gccgtagggt agccgagatt tagctaacga ctttggttac gttcgtgaat
    44641 tacgttcgat gcttaggtgc acggtttttt attttttaaa tattaaaccg attattaaga
    44701 gttgaaaata tatatttatt tatagaagct actttcttga agacaattca gcgtattata
    44761 cgtggaacat gtttgtggga agtagctttt ttatatgtga agtttgattc aagtgaactc
    44821 gatgtgcagt ttgaatgatt tttgtgtcaa tgaaaagtaa gaagttataa tttgatgata
    44881 aagaaatgat ggtgaaatga gggggagtat cttacaatag aattattaat gagatacgtt
    44941 atgattattg acaatcaaat gcctacggag gacatatgca aatatattta agtactttaa
    45001 cagagttaga ttatgataaa tctttaaata gtattgaaga aagttttgat gataatcctg
    45061 aaacgagttg gcaagcacgt gcgaaagtaa aacatttaag aaaatctcct tgctataatt
    45121 ttgaattaga agtaatagcg aaaaatgaaa ataacgatgt cgttggacac gttttattaa
    45181 ttgaagtaga aattaatagt gatgataaga cgtattatgg tttggcgatt gcctctttat
    45241 cagttcatcc tgaattacgt ggacaaaaat taggtcgtgg cttggttcaa gcagtagaag
    45301 agcgtgccaa agcacaagag tatagtacgg ttgttgtaga ccattgtttt gactactttg
    45361 aaaagttggg ttatcaaaat gctgctgagc atgacattaa attagaatct ggtgatgcac
    45421 cgttacttgt aaaatattta tgggataatt tgacggatgc accacacgga atcgtaaaat
    45481 ttccagaaca tttttattaa ttgttcaatt aagaagtaaa ggtattatca tgctataatg
    45541 agaggtaatt gtttatggag gtgctaactt gaattatcaa gccttatatc gtatgtacag
    45601 accccaaagt ttcgaggatg tcgtcggaca agaacatgtc acgaagacat tgcgcaatgc
    45661 gatttcgaaa gaaaaacagt cgcatgctta tatttttagt ggtccgagag gtacggggaa
    45721 aacgagtatt gccaaagtgt ttgctaaagc aatcaactgt ctaaatagca ctgatggaga
    45781 accttgtaat gaatgtcata tttgtaaagg cattacgcag gggactaatt cagatgtgat
    45841 agaaattgat gctgctagta ataatggcgt tgatgaaata agaaatatta gagacaaagt
    45901 taaatatgca ccaagtgaat cgaaatataa agtttatatt atagatgagg tgcacatgct
    45961 aacaacaggt gcttttaatg cccttttaaa gacgttagaa gaacctccag cacacgctat
    46021 ttttatattg gcaacgacag aaccacataa aatccctcca acaatcattt ctagggcaca
    46081 acgttttgat tttaaagcaa ttagcctaga tcaaattgtt gaacgtttaa aatttgtagc
    46141 agatgcacaa caaattgaat gtgaagatga agccttggca tttatcgcta aagcgtctga
    46201 agggggtatg cgtgatgcat taagtattat ggatcaggct attgcatttg gtgatggtac
    46261 gttaacattg caagatgcgt tgaatgtcac aggtagcgta catgatgaag cgttggatca
    46321 cttgtttgat gatattgtac aaggtgacgt acaagcatct tttaaaaaat accatcagtt
    46381 tataacagag ggtaaagaag tgaatcgcct aataaatgat atgatttatt ttgtcagaga
    46441 tacgattatg aataaaacat ctgagaaaga tactgagtat cgagcactga tgaacttaga
    46501 attagatatg ttatatcaaa tgattgatct tattaatgat acattagtgt cgattcgttt
    46561 tagtgtgaat caaaacgttc attttgaagt gttgttagta aaattagctg agcagattaa
    46621 gggtcaacca caagtgattg cgaatgtagc tgaaccagca caaattgctt catcgccaaa
    46681 cacagatgta ttgttgcaac gtatggaaca gttagagcaa gaattaaaaa cactaaaagc
    46741 acaaggagtg agtgtcgctc ctgctcaaaa atcttcggaa aagcctgcga gaggcataca
    46801 aaaatctaaa aatgcatttt caatgcaaca aattgcaaaa gtgctagata aagcgaataa
    46861 ggcagatatc aaattgttga aagatcattg gcaagaagtg attgatcatg ccaaaaacaa
    46921 tgataaaaaa tcactcgtta gtttattgca aaattcggaa cctgtggcgg caagtgaaga
    46981 tcacgtactt gtgaaatttg aggaagagat ccattgtgaa atcgtcaata aagacgacga
    47041 gaaacgtagt agtatagaaa gtgttgtatg taatatcgtt aataaaaacg ttaaagttgt
    47101 tggtgtacca tcagatcaat ggcaaagagt tcgaacggag tatttacaaa atcgtaaaaa
    47161 cgaaggcgat gatatgccaa agcaacaagc acaacaaaca gatattgctc aaaaagcaaa
    47221 agatcttttc ggtgaagaaa ctgtacatgt gatagatgaa gagtgataca tgacaagcga
    47281 tataatcgta tgtataatga aagaaacatc attttattga taaatattta ttgattttca
    47341 aggaggaaat ggaatatgcg cggtggcgga aacatgcaac aaatgatgaa acaaatgcaa
    47401 aaaatgcaaa agaaaatggc tcaagaacaa gaaaaactta aagaagagcg tattgtagga
    47461 acagctggcg gtggcatggt tgcagttact gtaactggtc ataaagaagt tgtcgacgtt
    47521 gaaatcaaag aagaagctgt agacccagac gatattgaaa tgctacaaga cttagtgtta
    47581 gcagctacta atgaagcgat gaataaagct gatgagctta ctcaagaacg tttaggtaaa
    47641 catactcaag gcttaaacat ccctggaatg tgatcataga tgcattatcc agaacctata
    47701 tcaaagctta ttgatagctt tatgaaattg ccaggcattg gtccaaagac agcccaacgt
    47761 ctggcttttc ataccttaga tatgaaagaa gacgatgttg ttcagtttgc caaagcatta
    47821 gtagatgtta agagagaatt aacatattgt agcgtatgtg gtcacattac tgaaaatgat
    47881 ccatgttata tttgtgaaga taaacaaaga gatcgttcag ttatttgtgt tgtggaagat
    47941 gacaaagatg tcatagctat ggaaaaaatg agagaataca aaggtttata tcacgtttta
    48001 catgggtcta tttcacctat ggatggcatt ggaccagaag atattaatat tccttcattg
    48061 attgaacgct tgaaaagcga tgaagttagc gaattaatct tagctatgaa cccgaactta
    48121 gagggggaat ctacagccat gtatatttct agattagtta agcctatagg tatcaaagtg
    48181 acgagattag cacaagggtt atcggtaggt ggcgatttag agtatgctga cgaagtaaca
    48241 ttatctaaag caatcgcagg tagaacagaa atgtaatgtc ttctattaaa catttttgaa
    48301 tttaatacta tagtaagaaa agtcacagtg taatcattgt ggcttttttt atggtgtggt
    48361 gtgatgtact actttatttg cggtgtggcg gtggtatggt ttacctagtt ttactgaggg
    48421 atgggtaatc tttaggaagc aagccgttgg ttgtgatttg ttacttctaa tagtaatgat
    48481 gtgaattgga ttatcgaatt agatttacgg ttatggtgtg ttggtgctat taatttgata
    48541 aatgcggttg atggttaatg actatgcaaa tgaaattctt ttgtaattga aatgatagat
    48601 gctggcttag tagttgtact tctttggtct aaagcttatt aaatcagcct gtatagcggt
    48661 gttttgagag attatttaaa acttgtaaat ttatttttaa tttctggtaa aaaaataacg
    48721 ttctgttttg cggttttttt gattgatatg gttagagaaa aatctgtttc ttgttctaaa
    48781 aaacgtacta tttataagtg gggatttttt aagttcgatt tttaggataa gggcgttcag
    48841 tacagatgac aaaggtgtaa tttttactgt tgttaagcag tttgaaagcc tgtatagtat
    48901 ttatttgttg aggcaaacaa aacaactcaa cttaagaaat aacttgaatt actaacgaaa
    48961 attaatttta aaaagttgtt gacttaaatg ttaataaaat gtataattaa ttcttgtcgg
    49021 taagaaa
//
LOCUS       DAPDIM010000013        47266 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000013 DAPDIM010000000
VERSION     DAPDIM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 47266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47266
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.013"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            161..307
                     /locus_tag="RFE25_000803"
     CDS             161..307
                     /locus_tag="RFE25_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815894.1"
                     /translation="MMLTAIYFSIFTFYISQYSLKLKTLYNIETDYNYKIVLLLKEGE
                     THES"
     gene            297..821
                     /locus_tag="RFE25_000804"
     CDS             297..821
                     /locus_tag="RFE25_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDU2815895.1"
                     /translation="MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKY
                     KLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIW
                     LDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRILRYNEIAFKKFDSHLLSISEI
                     YYELLNLIKASDQY"
     regulatory      808..905
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            980..2071
                     /gene="gcvT"
                     /locus_tag="RFE25_000805"
     CDS             980..2071
                     /gene="gcvT"
                     /locus_tag="RFE25_000805"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HDU2815896.1"
                     /translation="MSSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAVR
                     YEIGLFDVSHMGEIEVTGKDASQFVQYLLSNDTDNLTTSKALYTALCNEEGGIIDDLV
                     IYKLADDNYLLVVNAANTEKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLIN
                     QLVDEDVTEMKMFEFKQGVKLFGANVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEY
                     NVMPCGLGARDTLRLEAGLPLHGQDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQ
                     KENGAPRRTVGLELLEKGIARTGYEVMDLDGNIIGEVTSGTQSPSSGKSIALAMIKRD
                     EFEMGRELLVQVRKRQLKAKIVKKNQIDK"
     gene            2091..3437
                     /gene="gcvPA"
                     /locus_tag="RFE25_000806"
     CDS             2091..3437
                     /gene="gcvPA"
                     /locus_tag="RFE25_000806"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDU2815897.1"
                     /translation="MSHRYIPLTEKDKQEMLQTIGAKSIGELFGDVPSDILLNRDLNI
                     AEGEAETTLLRRLNRIASKNITKETHTSFLGAGVYDHYAPSVVDAMISRSEFYTAYTP
                     YQPEISQGELQAIFEFQTLICELTDMDVANSSMYDGMTSFAEACILAFSQTKKNKIVV
                     SKGLHYQALQVLHTYAKTRKEFEVVEIDLDGTVTDLKKLEAAVDDETAAVAVQYPNFY
                     GSIEDLEKIQSFIEDKKALFIVYANPLALGLLTPPGSFGADIVVGDTQPFGIPAQFGG
                     PHCGYFATTKKLMRKVPGRLVGQTQDDEGNRGFVLTLQAREQHIRRDKATSNICSNQA
                     LNALASSIAMSALGKQGIYDIAVQNIEHANYAKQQFIKKGFEVLDGTSFNEFVVKFDK
                     PIQQVNEELVKYNIIGGFDLGVVSDDFKNHMLIAVTELRTKDEIDTFVEKAGELND"
     gene            3430..4902
                     /gene="gcvPB"
                     /locus_tag="RFE25_000807"
     CDS             3430..4902
                     /gene="gcvPB"
                     /locus_tag="RFE25_000807"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDU2815898.1"
                     /translation="MTSKSSPLIFERSREGRYAYSLPKSDIKTNSVESLLDDKFIRKN
                     KAEFPEVAELDLVRHYTELSNKNFGVDNGFYPLGSCTMKYNPKINEKVARIPGFSESH
                     PLQDEDQVQGSLEIIYSLQEELKEITGMDEVTLQPAAGAHGEWTALMIFKAYHENNGE
                     GHRDEVIVPDSAHGTNPASASFAGFKSVTVKSNERGEVDIDDLKRVVNENTAAIMLTN
                     PNTLGIFEKNIMEIREIVHNAGGLLYYDGANLNAIMDKVRPGDMGFDAVHLNLHKTFT
                     GPHGGGGPGSGPVGVVKELASYLPKPMVIKDGDKFKYDNDIKNSIGRVKPFYGNFGIY
                     LRAYTYIRTMGATGLKEVSEAAVLNANYIKARLSEHFEIPYKQYCKHEFVLSGVRQKE
                     FGVRTLDMAKRLLDFGVHPPTIYFPLNVEEGMMIEPTETESKETLDYFIDTLISIAEE
                     AKNDPDKVLEAPHTTVIDRLDEATAARKPILKFENLKQEK"
     gene            complement(5267..5653)
                     /locus_tag="RFE25_000808"
     CDS             complement(5267..5653)
                     /locus_tag="RFE25_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDU2815899.1"
                     /translation="MSASLYIAIILVIAIIAYMIVQQILNKRAVKELDQNEFHNGIRK
                     AQVIDVREKVDYDYGHINGSRNIPMTMFRQRFQGLRKDQPVYLCDANGIASYRAARIL
                     KKNGYTDIYMLKGGYKKWTGKIKSKK"
     gene            5811..6641
                     /locus_tag="RFE25_000809"
     CDS             5811..6641
                     /locus_tag="RFE25_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDU2815900.1"
                     /translation="MTETWNFINTGSKDPYYNMAMDEALLNFVSRGEIDPVIRFYTWN
                     PATLSIGYFQRLQKEIDIDKVKEKGFGLVRRQTGGRGVLHDKELTYSVIVPESHPNMP
                     STVTEAYRVISQGLLEGFKNLGFDTYFAVPKTPEERQKLKQPRSSVCFDAPSWYELVV
                     EGRKIAGSAQTRQKGVILQHGSILQDIDIDELFDMFIYKNERLKLKMKEAFVEKAVAI
                     NDISDEHITISQMEEAFEKGFKKGLNIELKPLELTEAQLAEVEELTEKYRSDEWMFRK
                     "
     gene            complement(6705..6923)
                     /locus_tag="RFE25_000810"
     CDS             complement(6705..6923)
                     /locus_tag="RFE25_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815901.1"
                     /translation="MRNIIFYLVLIIAAIGLVMNLDAFIFSIVRMLISFAVIAGIIYL
                     IYYFFILTEDQRKYRKAMRKYKRNQRRK"
     gene            complement(6937..7518)
                     /locus_tag="RFE25_000811"
     CDS             complement(6937..7518)
                     /locus_tag="RFE25_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815902.1"
                     /translation="MKKLVSIVGATLLLAGCGSQNLAPLEEKTTDLREDNHQLKLDIQ
                     ELNQQISDSKSKIKGLEKDKENSKKTASNNTKIKLMNVTSTYYDKVAKALKSYNDIEK
                     DVSKNKGDKNVQSKLNQISNDIQSAHTSYKDAIDGLSLSDDDKKTSKNIDKLNSDLNH
                     AFDDIKNGYQNKDKKQLTKGQQALSKLNLNAKS"
     gene            7623..8684
                     /locus_tag="RFE25_000812"
     CDS             7623..8684
                     /locus_tag="RFE25_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDU2815903.1"
                     /translation="MSRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISK
                     DKQYLITDFRYIDQATKQAPNYEIINRKSTIIGEIKELLHQENFENIGFEGHHVSYDT
                     YLELNKSRISLISISNTVDKIRDVKDVDEIALIQKAANIVDETYEYILTVVKAGMTEK
                     ELKAILESKMLELGADGPSFDTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNG
                     YCSDITRTFAIGEPDPKLKEIYQIVLESQMKAINEIRPGMTGAEADAISRNYLESKGY
                     GKEFGHSLGHGIGLEIHEGPMLARTIQDKLQVNNCVTVEPGVYIEGLGGIRIEDDILI
                     TENGCQVFTKCTKDLIVLT"
     gene            8710..9267
                     /gene="efp"
                     /locus_tag="RFE25_000813"
     CDS             8710..9267
                     /gene="efp"
                     /locus_tag="RFE25_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDU2815904.1"
                     /translation="MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNL
                     RTGAIQEKTFRAGEKVEPAMIENRRMQYLYADEDNHVFMDNESFEQTELSSDYLKEEL
                     NYLKEGMEVQIQTYEGETIGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTL
                     NVPLFVNEGDVLIINTGDGSYISRG"
     gene            9741..10205
                     /gene="accB"
                     /locus_tag="RFE25_000814"
     CDS             9741..10205
                     /gene="accB"
                     /locus_tag="RFE25_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDU2815905.1"
                     /translation="MNFKEIKELIEILDKSTLTEINIEDTKGKVTLKKEKETEIITPQ
                     ISQMPVEAAAMPMPQAQSTDSNKTEAPKPTSDNHKTINAPMVGTFYKSPSPDEEAYVQ
                     VGDTVSNETTVCILEAMKLFNEIQAEISGEIVEILVEDGQMVEYGQPLFKVK"
     gene            10205..11560
                     /gene="accC"
                     /locus_tag="RFE25_000815"
     CDS             10205..11560
                     /gene="accC"
                     /locus_tag="RFE25_000815"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDU2815906.1"
                     /translation="MKKVLIANRGEIAVRIIRACRDLGIQTVAIYSEGDKDALHTQIA
                     DEAYCVGPTLSKDSYLNIPNILSIATSTGCDGVHPGYGFLAENADFAELCEACQLKFI
                     GPSYQSIQKMGIKDVAKAEMIKANVPVVPGSDGLMKDVSEAKKIAKKIGYPVIIKATA
                     GGGGKGIRVARDEKELETGFRMTEQEAQTAFGNGGLYMEKFIENFRHIEIQIVGDSYG
                     NVIHLGERDCTIQRRMQKLVEEAPSPILDDETRREMGNAAVRAAKAVNYENAGTIEFI
                     YDLNDNKFYFMEMNTRIQVEHPVTEMVTGIDLVKLQLQVAMGDVLPYKQEDIKLTGHA
                     IEFRINAENPYKNFMPSPGKIEQYLAPGGYGVRIESACYTNYTIPPYYDSMVAKLIIH
                     EPTRDEAIMAGIRALSEFVVLGIDTTIPFHIKLLNNDIFRSGKFNTNFLEQNSIMNDE
                     G"
     gene            11575..11937
                     /locus_tag="RFE25_000816"
     CDS             11575..11937
                     /locus_tag="RFE25_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDU2815907.1"
                     /translation="MVKVTDYSNSKLGKVEIAPEVLSVIASIATSEVEGITGHFAELK
                     ETNLEKVSRKNLSRDLKIESKEDGIYIDVYCALKHGVNISKTANKIQTSIFNSISNMT
                     AIEPKQINIHITQIVIEK"
     gene            11997..12386
                     /gene="nusB"
                     /locus_tag="RFE25_000817"
     CDS             11997..12386
                     /gene="nusB"
                     /locus_tag="RFE25_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDU2815908.1"
                     /translation="MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDDNPDLDFEF
                     IHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMN
                     EAVELTKQFSDDDHYKFINGVLSNIKK"
     gene            12403..13740
                     /locus_tag="RFE25_000818"
     CDS             12403..13740
                     /locus_tag="RFE25_000818"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDU2815909.1"
                     /translation="MSDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHL
                     YFNVKDKESVISAMMFKGSASKLNFEPKEGDEVLLEARVSVFERRGNYQIYVNKMQLD
                     GIGNLYQKLEALKKKLTEEGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSR
                     FPLAEQIQISTLVQGEKAKDDIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVV
                     RAIYNCKTPIISAVGHETDFTLSDFAADIRAATPTQAAVIATPDQYELLQQIQQYQFT
                     LTRFIKKHLEQQRKHVEHLSSYYKFKQPTLLYDQQIQRRDDLEKRLKQQIQATFEQQR
                     HRLMLLQQRYNLKALLSSVNQEQQNNLQLTNQLVKLLNSKILSYKNDLKNKVENLNNL
                     SPTNTMLRGYAIVNKKDEVITSTKDLTENDQLTLTMKDGLVDAKVTKVRCNND"
     gene            13733..13963
                     /locus_tag="RFE25_000819"
     CDS             13733..13963
                     /locus_tag="RFE25_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDU2815910.1"
                     /translation="MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSA
                     ACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE"
     gene            13941..14822
                     /locus_tag="RFE25_000820"
     CDS             13941..14822
                     /locus_tag="RFE25_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDU2815911.1"
                     /translation="MTNLPMNKLIDEVNNELSVAINKSVMDTQLEESMLYSLNAGGKR
                     IRPVLLLLTLDSLNTEYELGVKSAIALEMIHTYSLIHDDLPAMDNDDYRRGKLTNHKV
                     YGEWTAILAGDALLTKAFELISSDDRLTDEVKIKVLQRLSIASGHVGMVGGQMLDMQS
                     EGQPIDLETLEMIHKTKTGALLTFAVMSAADIANVDDATKEHLESYSYHLGMMFQIKD
                     DLLDCYGDEAKLGKKVGSDLENNKSTYVSLLGKDGAEDKLTYHRDAAVDELTQIDEQF
                     NTKHLLEIVDLFYSRDH"
     gene            15254..15706
                     /gene="argR"
                     /locus_tag="RFE25_000821"
     CDS             15254..15706
                     /gene="argR"
                     /locus_tag="RFE25_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HDU2815912.1"
                     /translation="MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSR
                     DIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPG
                     NAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL"
     gene            15722..17401
                     /gene="recN"
                     /locus_tag="RFE25_000822"
     CDS             15722..17401
                     /gene="recN"
                     /locus_tag="RFE25_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDU2815913.1"
                     /translation="MLQTLSIKQFAIIEELEIQFSDGLTVLSGETGSGKSIIIDAIGQ
                     LIGMRASSDFVRHGEKKAVIEGIFDIDESKDAIHILKNMDIDVDEDFLLVKREIFSSG
                     KSLCKINNQTVTLQDLRKVMQELLDIHGQHETQSLLKQKYHLTLLDNYAESRYQDLLD
                     KYHQTFQNYKAKKQELEDLESADQALLQRLDLMKFQLEELSEAHLKEGEIEQLEIDIK
                     RIQNSEKLSLALNNAHMTLTDENAITDRLYELSNHLLTINDIVPNKYDKLKEDIDQFY
                     YILEDAKHELYDEMANTEFDEQVLNEYESRMNLLNNLKRKYGKDISELIAYQEKLNNE
                     INKIENYEQSTSQLREEINALYNQVIEVGQALSKQRRIVARELRDHIVSEIQNLQMKD
                     ANLEISFKKLEEPNIDGIEFVEFLISPNKGEPLKSLNKIASGGELSRIMLALKSIFVK
                     SRGQTAILFDEVDSGVSGQAAQKMAEKMRDIAEYIQVICISHLPQVASMSDHHLLISK
                     SSKDDRTTTQVQELIGDDKVDEIARMISGASVTDLTRENAREMIQHNQRRR"
     gene            17552..18973
                     /gene="lpdA"
                     /locus_tag="RFE25_000823"
     CDS             17552..18973
                     /gene="lpdA"
                     /locus_tag="RFE25_000823"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDU2815914.1"
                     /translation="MSEKQYDLVVLGGGTAGYVAAIRASQLGKKVAIVERQLLGGTCL
                     HKGCIPTKSLLKSAEVFQTVKQAAMFGVDVKDANVNFENMLARKEDIINQMYQGVKHL
                     MQHNHIDIYNGTGRILGTSIFSPQSGTISVEYEDGESDLLPNQFVLIATGSSPAELPF
                     LSFDHDKILSSDDILSLKTLPSSIGIIGGGVIGMEFASLMIDLGVDVTVIEAGERILP
                     TESKQASQLLKKSLSARGVKFYEGIKLSENDINVNEDGVTFEISSDIIKVDKVLLSIG
                     RKPNTSDIGLNNTKIKLSTSGHILTNEFQQTEDKHIYAAGDCIGKLQLAHVGSKEGVV
                     AVDHMFEGNPIPVNYNMMPKCIYSQPEIASIGLNIEQAKAEGMKVKSFKVPFKAIGKA
                     VIDSHDANEGYSEMVIDQSTEEIVGINMIGPHVTELINEASLLQFMNGSALELGLTTH
                     AHPSISEVLMELGLKAESRAIHV"
     gene            18989..19981
                     /locus_tag="RFE25_000824"
     CDS             18989..19981
                     /locus_tag="RFE25_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDU2815915.1"
                     /translation="MIDYKSLGLSEEDLKVIYKWMDLGRKIDERLWLLNRAGKIPFVV
                     SGQGQEATQIGMAYALEEGDITAPYYRDLAFVTYMGISAYDTFLSAFGKKDDVNSGGK
                     QMPSHFSSRAKNILSQSSPVATQIPHAVGAALALKMDGKKKIATATVGEGSSNQGDFH
                     EGLNFAGVHKLPFVCVIINNKYAISVPDSLQYAAEKLSDRALGYGIHGEQVDGNDPLA
                     MYKAMKEARDRAISGQGSTLIEAVTSRMTAHSSDDDDQYRTKEEREALKKADCNEKFK
                     KELLSAGIIDDAWLAEIEAEHKDIINKATKAAEDAPYPSVEEAYAFVYEEGSLN"
     gene            19981..20964
                     /locus_tag="RFE25_000825"
     CDS             19981..20964
                     /locus_tag="RFE25_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDU2815916.1"
                     /translation="MAKLSYLEAIRQAQDLALQQNKDVFILGEDVGKKGGVFGTTQGL
                     QQQYGEDRVIDTPLAESNIVGTAIGAAMVGKRPIAEIQFADFILPATNQIISEAAKMR
                     YRSNNDWQCPLTIRAPFGGGVHGGLYHSQSIESIFASSPGLTIVIPSTPYDAKGLLLS
                     SIESNDPVLYFEHKKAYRFLKEEVPEEYYTVPLGKADVKREGEDLTVFCYGLMVNYCL
                     QAADILAADGINVEVVDLRTVYPLDKETIIDRAKNTGKVLLVTEDNLEGSIMSEVSAI
                     IAEHCLFDLDAPIMRLAAPDVPSMPFSPVLENEIMMNPEKILNKMRELAEF"
     gene            20977..22251
                     /locus_tag="RFE25_000826"
     CDS             20977..22251
                     /locus_tag="RFE25_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDU2815917.1"
                     /translation="MEITMPKLGESVHEGTIEQWLVSVGDHIDEYEPLCEVITDKVTA
                     EVPSTISGTITEILVEAGQTVAIDTFICKIETADEKTNETTEEIQAKVDEHTQKSTKK
                     ASATVEQTFTAKQNQPRNNGRFSPVVFKLASEHDIDLSQVVGSGFEGRVTKKDIMSVI
                     ENGGTTAQSDKQVQTKSTSVDTSSNQSSEDNSENSTIPVNGVRKAIAQNMVNSVTEIP
                     HAWMMIEVDATNLVNTRNHYKNSFKNKEGYNLTFFAFFVKAVADALKAYPLLNSSWQG
                     NEIVLHKDINISIAVADENKLYVPVIKHADEKSIKGIAREINTLATKARNKQLTTEDM
                     QGGTFTVNNTGTFGSVSSMGIINHPQAAILQVESIVKKPVVINDMIAIRSMVNLCISI
                     DHRILDGLQTGKFMNHIKQRIEQYTLENTNIY"
     gene            22602..23039
                     /locus_tag="RFE25_000827"
     CDS             22602..23039
                     /locus_tag="RFE25_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrxA/BrxB family bacilliredoxin"
                     /protein_id="HDU2815918.1"
                     /translation="MDMNFDLYMNGVVEQARNEIESAGYEQLTTAEDVDKVLKQDGTT
                     LVMINSVCGCAGGIARPAASHALHYDVLPDRLVTVFAGQDKEATQRAREYFEGYAPSS
                     PSFALVKDGKITEMIERHQIEGHDVMNVINQLQTLFNKYCEER"
     gene            23053..24033
                     /locus_tag="RFE25_000828"
     CDS             23053..24033
                     /locus_tag="RFE25_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDU2815919.1"
                     /translation="MLKLNPYKIGFRTIKTAVGMTLGVIISKLLGLDNYASSAILVVL
                     CIKHTKVHSLQAIISRLVSCFLVLFLGSAIFSLLGQSPIVLGIIVLLFIPLTVVLKVQ
                     EGVITSCVILLHVFNAKSIDAHLIVNETLLLLIGLSIAFTMNLMMPSLDKQLDEYKCK
                     IEQQIADIFSKYSYICEKYEDTIAIEFEVLLLNIKKAKSIAFRDVKNHFVRNENSYYH
                     YFDMREEQVELLMRMKPLIESICHKDPLLNDVSSLLKEIGLNVNSNDYTAMRLHNLYE
                     TRLKLDELPLPTTHKALNSRASIIQILNELEEYLQIKSQFGSLKMHSEVA"
     gene            complement(24160..24339)
                     /gene="prli42"
                     /locus_tag="RFE25_000829"
     CDS             complement(24160..24339)
                     /gene="prli42"
                     /locus_tag="RFE25_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stressosome-associated protein Prli42"
                     /protein_id="HDU2815920.1"
                     /translation="MLVISSQVKSFISYVVIINTKVIHLEAHKMQNKVLRIIIIVMLV
                     SVVLALLLTSIIPIL"
     gene            24602..25735
                     /locus_tag="RFE25_000830"
     CDS             24602..25735
                     /locus_tag="RFE25_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDU2815921.1"
                     /translation="MINEQRLLNTFLELVQIDSETGNESTIQPILKEKFIALGLDVKE
                     DEAAKHPKLGANNLVCTMNSTIEEGEVPKLYLTSHMDTVVPAINVKPIVKDDGYIYSD
                     GTTILGADDKAGLAAMLEVLQVIKEQQIPHGQIQFVITVGEESGLIGAKELNSELLDA
                     DFGYAIDASADVGTTVVGAPTQMLISAKIIGKTAHASTPKEGVSAINIAAKAISRMKL
                     GQVDEITTANIGKFHGGSATNIVADEVILEAEARSHDPERIKTQVKHMTDVFETTASE
                     LGGKAEVTVEQSYPGFKINDNEAVVKIAQESARNLGLSANTIISGGGSDGSIINTFGI
                     PSVILGVGYEKIHTTNERMPIKSLNLLASQVLEIIKIVARQSK"
     gene            25803..27209
                     /gene="gndA"
                     /locus_tag="RFE25_000831"
     CDS             25803..27209
                     /gene="gndA"
                     /locus_tag="RFE25_000831"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDU2815922.1"
                     /translation="MTQQIGVIGLAVMGKNLAWNIESRGYSVSVFNRSSEKTDLMVEE
                     SKGKNIHPTYSLEEFVNSLEKPRKILLMVQAGKATDATIDSLLPLLDDGDILIDGGNT
                     NYQDTIRRNKALAQSAINFIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAA
                     KAKDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTF
                     KDWNAGELESYLIEITGDIFMKLDENKEALVEKILDTAGQKGTGKWTSINALELGIPL
                     TIITESVFARFISSIKEERVNASKELNGPKASFDGDKKDFLEKIRKALYMSKICSYAQ
                     GFAQMRKASEDNEWNLKLGDLAMIWREGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYF
                     KNIVTEYQDALRDVVATGVQNGVPTPGFSSSINYYDSYRAADLPANLIQAQRDYFGAH
                     TYERKDKEGVFHTQWIEE"
     gene            27525..28742
                     /locus_tag="RFE25_000832"
     CDS             27525..28742
                     /locus_tag="RFE25_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2815923.1"
                     /translation="MSYTSVLFNKNFTFYLIGIAFSNMGSAFTTFVFPLMILKLTGSA
                     FQVGIVSALSFIPYAILGLPAGALIDRLNKKTIMKCADIIRFVSYLSIPVLSFFNMLS
                     IFQIYVVAIISGIGLVFHSISEVSIIPSIVKEEDLASANSYIYATQNVSEFLGPIIGG
                     LLYTYMGYSILIFIDSMTFLLSFFSLILIKIETKSIFNQEKLSGKNFLSDVKVGFDYL
                     LSNSTIRVMAVVVSLSNLIISPYYIYIVMFVKEDMNQSSQALGLVLGISSLGALIGSL
                     SASFLLKLFNFGKLIVIILFLDTIFRLMLPFSTYIFILIPLLGLTYMTQSILNIAIIT
                     LRQKKCSENMLGRVNSVFKTMVFAFRPIGLFLGGILLENKGGFYALTISAVLFIPLVL
                     YILKNRFYQVEEY"
     gene            29209..29580
                     /locus_tag="RFE25_000833"
     CDS             29209..29580
                     /locus_tag="RFE25_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDU2815924.1"
                     /translation="MEKLNQVMLYVDDVEKAKAFWTETLEFVVVSETPLAEDYVAVEV
                     SPTKDAETSLTIMAKEFIEKHSPEVNLGTPSLMFKEKNFDALYSKLNDLGLTGHDIVE
                     MDGQRVFNFQDGQGNYFAVSD"
     gene            29519..29773
                     /locus_tag="RFE25_000834"
     CDS             29519..29773
                     /locus_tag="RFE25_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815925.1"
                     /translation="MVNVYLISKMDKVIILQLVTKQSILIFIQTFILIFGLNFSMKVL
                     FLSFYAIVCTNLLTFLERVTKLLLYRGWKRFPMQKLTGGD"
     gene            29774..30793
                     /locus_tag="RFE25_000835"
     CDS             29774..30793
                     /locus_tag="RFE25_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDU2815926.1"
                     /translation="MVTIKDVALKAGVSPSTVSRVIKGNKRISEATISKVKKVMEELN
                     YFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVS
                     NNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
                     THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETVASQFNLDYQI
                     IETSNEREVILNYMQNLHTRLKDPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMT
                     ATFNDSYLTEIASPPQTCIDIKPRMLGQQAGSAILNILKNKAQDVIELVIIDTELKIR
                     KSTQR"
     gene            30809..32458
                     /locus_tag="RFE25_000836"
     CDS             30809..32458
                     /locus_tag="RFE25_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDU2815927.1"
                     /translation="MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDLG
                     IDVIWLSPMFKSPNDDNGYDISDYQEIMDEFGTMEDFDCLLKGIHDRGMKLILDLVVN
                     HTSDEHPWFIESKSSKDNPKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYY
                     FHLFSKKQPDLNWGNPEVRDAVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPE
                     GKTYAPAFDVDMNQPGIQTWLQEMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGK
                     FNMIFQFEHLGLWNSGDSHFDVNSYKSVLNRWQKQLENKGWNALFIENHDQPRRVSTW
                     GDDDKYWYESATSHAAVYFLQQGTPFIYQGQEIGMTNYPFESIETFNDVAVKNDYQIV
                     KAQGGDVDALLAKYKDENRDNSRTPMQWDDTLNGGFTNGEPWFPVNLNYKTINVAQQL
                     EDEHSVLQFYKDLIQLRKSNDVYVYGQFDLVDAENSQVFAYTRTLNEKQVLIVGNLTN
                     HEAELTVPFDLSHGEVKLFNYDAKVNLKQLRPYEACVIELN"
     gene            complement(32540..33406)
                     /locus_tag="RFE25_000837"
     CDS             complement(32540..33406)
                     /locus_tag="RFE25_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDU2815928.1"
                     /translation="MDVIKQIQQAIVYIEDRLLEPFNLQELSDYVGLSPYHLDQSFKM
                     IVGLSPEAYARARKMTLAANDVINGATRLVDIAKKYHYANSNDFANDFSDFHGVSPIQ
                     ASTKKDELQIQERLYIKLSTTERAPYPYRLEETDDISLVGYARFIDTKYLSHPFNVPD
                     FLEDLLIDGKIKELRRYNDVSPFELFVISCPLENGLEIFVGVPSERYPAHLESRFLPG
                     KHCAKFNLQGEIDYATNEAWYYIESSLQLTLPYERNDLYVEVYPLDISFNDPFTKIQL
                     WIPVKQSPYDED"
     gene            complement(33636..35120)
                     /locus_tag="RFE25_000838"
     CDS             complement(33636..35120)
                     /locus_tag="RFE25_000838"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDU2815929.1"
                     /translation="MSTKNKHIPCLITIFGATGDLSHRKLFPSIFHLYQQDNLDEHIA
                     IIGIGRRDITNDDFRNQVKSSIQKHVKDTNKIDAFMEHVFYHRHDVSNEESYQELLDF
                     SNELDSQFELKGNRLFYLAMAPQFFGVISDYLKSSGLTDTKGFKRLVIEKPFGSDLKS
                     AEALNNQIRKSFKEEEIYRIDHYLGKDMVQNIEVLRFANAMFEPLWNNKYISNIQVTS
                     SEILGVEDRGGYYESSGALKDMVQNHMLQMVALLAMEAPISLNSEDIRAEKVKVLKSL
                     RHFQSEDVKKNFVRGQYGEGYIDGKQVKAYRDEDRVADDSNTPTFVSGKLTIDNFRWA
                     GVPFYIRTGKRMKSKTIQVVVEFKEVPMNLYYETDKLLDSNLLVINIQPNEGVSLHLN
                     AKKNTQGIETEPVQLSYSMSAQDKMNTVDAYENLLFDCLKGDATNFTHWEELKSTWKF
                     VDAIQDEWNMVDPEFPNYESGTNGPLESDLLLARDGNHWWDDIQ"
     gene            35433..36353
                     /gene="rnz"
                     /locus_tag="RFE25_000839"
     CDS             35433..36353
                     /gene="rnz"
                     /locus_tag="RFE25_000839"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDU2815930.1"
                     /translation="MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQH
                     QILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVE
                     MSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
                     VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNE
                     RVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNT
                     EDINEIYQILIQNEDTPNFNFVKDFDSFKV"
     gene            complement(36456..37271)
                     /gene="proC"
                     /locus_tag="RFE25_000840"
     CDS             complement(36456..37271)
                     /gene="proC"
                     /locus_tag="RFE25_000840"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDU2815931.1"
                     /translation="MKLVFYGAGNMAQAIFTGIINSSNLDANDIYLTNKSNEQALKAF
                     AEKLGVNYSYDDATLLKDADYVFLGTKPHDFDALATRIKPHITKDNCFISIMAGIPID
                     YIKQQLECQNPVARIMPNTNAQVGHSVTGISFSNNFDPKSKDEINDLVKAFGSVIEVS
                     EDHLHQVTAITGSGPAFLYHVFEQYVKAGTKLGLEKEQVEESIRNLIIGTSKMIERSD
                     LSMAQLRKNITSKGGTTQAGLDTLSQYDLVSIFEDCLNAAVDRSIELSNVEDQ"
     gene            37413..38168
                     /locus_tag="RFE25_000841"
     CDS             37413..38168
                     /locus_tag="RFE25_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDU2815932.1"
                     /translation="MKGQHFIVTGGTSGLGLSIVRKLLENKVHVTLLVRDVDKATRIF
                     EQELGKTINVIPCDLNDLKSIQALQFEDNTSFDGFIYSAGLGYFKSISDHSFSEMIET
                     YQLNLISFNVLYTVLRPYLTSNAHIVGISSQAAFSTQANAAHYGASKAGFYALMNALR
                     LESPNLHIMTVNVGPIDTPFHQKADPSMKYAKKMGEIMLDANQLAEDIIYGIKTKQLE
                     INRPKWMHHALKMYQIAPRFFERCFPKLFKNKA"
     gene            38184..38432
                     /locus_tag="RFE25_000842"
     CDS             38184..38432
                     /locus_tag="RFE25_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815933.1"
                     /translation="MNCQSESVVRLCVRYAEQLSVFEEFTVLDILGDISVDQISDGTL
                     YYTCEKFKLLVLQGNVLGVQIITNNDESTCEVKYRKMF"
     gene            complement(38648..39577)
                     /locus_tag="RFE25_000843"
     CDS             complement(38648..39577)
                     /locus_tag="RFE25_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDU2815934.1"
                     /translation="MYRKENRHAKNILKSGIALSELGLGCMSLGTDLKKAEQIIDCAV
                     ENGITYFDTADMYDKGINESVVGKALLKYQQRDDIFIGTKVGNRLTKDGSTTWDPSKS
                     YIKEAVKGSLKRLGIDHIDLYQLHGGTIDDPLDETISAFDELKQEGIIRAYGISSIRP
                     NVIDYYLKHSQIETIMSQFNLIDNRPESLLDAIHNNDVKVLARGPVSKGLLTSNSVNV
                     LDNKFKDGIFDYSHDELGETIASIKEIESNLSALTFSYLTSHDVLGSIIVGASSVDQL
                     KENIENYHTKVGLDQIKTARARVKDLEYTNHLV"
     gene            39637..40179
                     /locus_tag="RFE25_000844"
     CDS             39637..40179
                     /locus_tag="RFE25_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDU2815935.1"
                     /translation="MDLNEKTIDRTVIYNGKIVDVEIHTVTLPNGETSTRELVYHNGA
                     VAVCALTPKKEVVLVKQYRKPVEKPLLEIPAGKLEDDENRVEAAKRELEEETGYIAKE
                     LTHVVDMYGSPGFCDEQLSIYFTDNLEEGTVHLDEDEFVEVIKVPIENVKSMLMNKEI
                     EDAKTIIALQHLLLNYNHSK"
     gene            40284..40733
                     /locus_tag="RFE25_000845"
     CDS             40284..40733
                     /locus_tag="RFE25_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDU2815936.1"
                     /translation="MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVY
                     LKVKDKAPEIGLATVYRTLELLAELKVVDKINFGDGVARFDLRKEGAKHFHHHLVCME
                     CGRVDEIDEDLLPEVENRVENEFNFKILDHRLTFHGVCETCQAKGKG"
     gene            40782..41669
                     /gene="xerD"
                     /locus_tag="RFE25_000846"
     CDS             40782..41669
                     /gene="xerD"
                     /locus_tag="RFE25_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDU2815937.1"
                     /translation="METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISH
                     IDFIDRQLIQECLGHLIDQGQSAKSIARFISTIRSFHQFAIREKYAAKDPTVLLDSPK
                     YDKKLPDVLNVDEVLALLETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNL
                     IMGFVRVFGKGDKERIVPLGDAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSR
                     QAIWKMIKQNGVKANIKKTLTPHTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLY
                     THVSKSQIRKMYNQFHPRA"
     gene            complement(41747..42253)
                     /locus_tag="RFE25_000847"
     CDS             complement(41747..42253)
                     /locus_tag="RFE25_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF309 domain-containing protein"
                     /protein_id="HDU2815938.1"
                     /translation="MQQALINFYYQFHTKQHYFLCHDILEDAWKAENNYSKQDAVVSL
                     ILFATACYHYRRNNLKGAYKSFNKSKEIIQNAKDRDALYLNLNDYQLLIEQQIAKLNA
                     AKPFSSVILPITPVFERIIKANYPDYDYNQETATDPFIVDHHMRRDRSEVIAAKEEAI
                     QLRKHRRN"
     gene            42345..43076
                     /locus_tag="RFE25_000848"
     CDS             42345..43076
                     /locus_tag="RFE25_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDU2815939.1"
                     /translation="MYEVKLDAFNGPLDLLLHLIQKFEIDIYDIPMQALTEQYMQYVH
                     AMKQLEINIASEYLVLASELLMIKSKMLLPQSTSDMDVDDDPREDLVGRLIEYQNYKE
                     YTAILNDMKEERDFYFTKRPTDLSHLETDESWDPNHTIDLTELIVAYQRVKNRVELNT
                     PKSVEIRKETFTIQQATEQVTSRLKDKDHFNFFSLFTFSEPIEQVVTHFLAILEMSKA
                     GIINIEQQRNFEDINIIRGVNYHFG"
     gene            43069..43611
                     /gene="scpB"
                     /locus_tag="RFE25_000849"
     CDS             43069..43611
                     /gene="scpB"
                     /locus_tag="RFE25_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDU2815940.1"
                     /translation="MDNHGILESLLFTAGDEGLDEKQLLEILDMSKDQLVELIENYSS
                     HGLMIQRFGTTYVLTTKKEAATYIEQLIEQKSQMKLSQAAMEVLSIIAYNQPLSRSDI
                     ELIRSINSDGAVKTLIAKGLVEAKVVNEQRSQQLITTDLFLNVFGISNIEDLPTTEED
                     DEEMDAFFSNLVNQKGENND"
     gene            43604..44341
                     /locus_tag="RFE25_000850"
     CDS             43604..44341
                     /locus_tag="RFE25_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDU2815941.1"
                     /translation="MTKELERLQKRIANSGYTSRRKAETLISEGKVKVNGTTVTELGT
                     KVKPSDTIEVEGIKIELEDKIYILFHKPTQVITSVSDDRGRTVVTDYFKDIEARIYPV
                     GRLDYDTSGLLLLTNDGEFTNLMTHPRYQIKKKYVAKLKGYLMREEVKALEKGIELED
                     GMTQPAEVKVKKQDKDKNTTLVEITITEGRNRQVRRMFEHFGHQVTKLSRIEYGPLNV
                     VGLNAGEGRVLTPHEVKVMRHLAEHGK"
     gene            44474..45199
                     /gene="srrA"
                     /locus_tag="RFE25_000851"
     CDS             44474..45199
                     /gene="srrA"
                     /locus_tag="RFE25_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator SrrA"
                     /protein_id="HDU2815942.1"
                     /translation="MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAME
                     NNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVK
                     PFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLT
                     PKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAA
                     HMIQTVWGVGYKFEVKSNDEPAK"
     gene            45180..46931
                     /gene="srrB"
                     /locus_tag="RFE25_000852"
     CDS             45180..46931
                     /gene="srrB"
                     /locus_tag="RFE25_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     SrrB"
                     /protein_id="HDU2815943.1"
                     /translation="MMSRLNSVVIKLWLTIILIVTTVLILLSIALITFMQYYFTQETE
                     NAIREDARRISSLVEQSHNKEEAIKYSQTLIENPGGLMIINNKHRQSTASLSNIKKQM
                     LNEVVNNDHFDDVFDKGKSVTRNVTIKEKGSSQTYILLGYPTKAQKNSHSKYSGVFIY
                     KDLKSIEDTNNAITIITIITAVIFLTITTVFAFFLSSRITKPLRRLRDQATRVSEGDY
                     SYKPSVTTKDEIGQLSQAFNQMSTEIEEHVDALSTSKNIRDSLINSMVEGVLGINESR
                     QIILSNKMANDIMDNIDEDAKAFLLRQIEDTFKSKQTEMRDLEMNARFFVVTTSYIDK
                     IEQGGKSGVVVTVRDMTNEHNLDQMKKDFIANVSHELRTPISLLQGYTESIVDGIVTE
                     PDEIKESLAVVLDESKRLNRLVNELLNVARMDAEGLSVNKEVQPIAALLDKMKIKYRQ
                     QADDLGLNMTFNYCKKRVWSYDMDRMDQVLTNLIDNASRYTKPGDEIAITCDENESED
                     ILYIKDTGTGIAPEHLQQVFDRFYKVDAARTRGKQGTGLGLFICKMIIEEHGGSIDVK
                     SELGKGTTFIIKLPKPE"
BASE COUNT        16995 a         6543 c         8690 g        15038 t
ORIGIN      
        1 tattaaaata acgataacag ttaaagtcgg tacaaatctg cagactaaaa ctatttatgt
       61 ataacttact agaatttaaa tgagtactat taaaaaggat gtgaaataat ttattaattt
      121 tgatttatat aaagaaaaag gatatgtaac tccgttctta ttgatgctaa cagcaattta
      181 tttttccatt ttcacttttt atatcagtca atatagttta aaattaaaga cattatataa
      241 tattgaaact gactataact ataagattgt tttgttattg aaagaagggg aaacgcatga
      301 atcatgataa atcaccaata attttaattg gtttcatggg taccggtaaa tctacgattg
      361 gtaaatacgt tgcagatgag caaaatttat catttattga tatagattca tatatcgaag
      421 agaagtataa gttaacaata ccagaaatat ttagtaaaca tggtgaacaa tatttcagga
      481 atttagagtt cacatgtttg caagaatgta ttaacactgc agatataatt gctactggtg
      541 gtggtattat tgaaagtgaa gaggcattta attttttgaa aaatcaaaaa aacattattt
      601 ggttagattg taatattgat attatatata gtcgaatcaa tgatgaccca catcgaccta
      661 atgcaaataa taagacaatc aagcagttaa atgacttgta ttgctcgcgg attttaagat
      721 ataatgaaat cgcattcaag aaatttgata gtcatttgct atcaatttca gaaatatatt
      781 atgaattgct aaatttaata aaagcgagtg atcagtatta gagagaatag agcgttaaga
      841 ctctatcgcc gaaggtgcaa gtaatttatt acgaaactct caggcaaaag gataatactg
      901 taacgcgttc ctgaattggt gatttataaa cagggtagcg attgctatcc tgtttttata
      961 attttaaggg ggtatttcaa tgtcaagtga tttaaaacaa acacctttat atcaaaatta
     1021 tgttgataga ggtgcaaaaa ttgtggaatt cggaggatgg gcgatgcctg ttcaattttc
     1081 aagtattaaa gaggagcata atgctgttcg atacgaaatt ggcctgtttg atgttagtca
     1141 tatgggtgaa attgaagtaa caggtaaaga tgctagtcag tttgtgcaat atttattatc
     1201 aaatgatact gataatttaa ctacttcaaa agcattatat actgctttat gtaatgaaga
     1261 aggcggtatt attgatgatt tagtaatata taaattagct gacgacaatt atttattagt
     1321 tgttaatgct gctaatactg aaaaagattt taattggatt ttaaaacaca aagagaaatt
     1381 tgatgttgaa gtacaaaatg tatcaaacca atatggtcaa ttagcaatac aaggaccaaa
     1441 agctagagat ttaattaatc aattagttga tgaagatgta actgaaatga aaatgtttga
     1501 atttaaacag ggtgtcaaat tatttggagc aaacgtcatt ttatctcagt caggttacac
     1561 aggtgaagat gggtttgaaa tttattgtaa tatcgatgat actgaaaaaa tttgggatgg
     1621 tttattagag tataatgtta tgccatgtgg gttaggcgct cgtgatacat taagattaga
     1681 ggctggattg ccattacatg gacaagattt aactgaatca attacaccat atgaaggtgg
     1741 tatcgctttt gcaagtaaac cattaattga tgctgatttt attggtaaat ctgtattaaa
     1801 agatcaaaaa gaaaatggtg caccaagaag aacagtggga ttagaattac ttgaaaaagg
     1861 aattgcaaga actggttatg aagttatgga tttagatgga aatattattg gagaagtaac
     1921 ttcaggaaca cagtctccat catcaggaaa atcaattgca cttgcaatga taaaaagaga
     1981 tgagtttgaa atgggtagag agttgcttgt tcaagttcgt aagcgtcaat taaaagcgaa
     2041 aattgttaag aaaaatcaaa ttgataaata attaaaaagg ggtgtgcatt gtgagtcatc
     2101 gttatatacc tttaactgaa aaagacaagc aagaaatgtt acaaacaatt ggtgcaaaat
     2161 ctataggaga attattcggt gatgtaccaa gtgacatttt attaaataga gatttaaata
     2221 ttgctgaagg cgaagcggaa acaacgttac ttagaagatt aaatcgcatt gcaagcaaga
     2281 atatcactaa agaaacgcat acatcatttt tgggtgctgg tgtttatgat cattacgcgc
     2341 catcagttgt ggatgctatg atttcaagat cagaatttta cacagcatat acgccatatc
     2401 aaccggaaat ttctcaaggt gaattacaag ccatttttga gttccaaact ttaatttgtg
     2461 aattaacaga tatggatgta gcaaattctt ctatgtatga tgggatgact agctttgctg
     2521 aagcatgtat cttagcattt agtcaaacaa agaaaaataa aattgtagtc tcaaaaggtt
     2581 tacattatca agcattacaa gtacttcata cttatgctaa gacgcgtaag gaattcgaag
     2641 tagtggaaat cgatttagat ggcactgtta cagatttgaa aaaattagaa gcagcagtgg
     2701 atgatgaaac agcagctgtt gcagtacaat atccaaactt ttacggttca attgaagatc
     2761 ttgaaaagat tcaaagcttt attgaagata aaaaagcatt atttatcgta tatgcaaatc
     2821 cattagcatt gggattactt acacctccag gttcatttgg tgcagatatt gttgtaggtg
     2881 atactcagcc attcggaatt cctgctcaat tcggtgggcc acattgtgga tattttgcaa
     2941 cgacgaaaaa gttaatgcgt aaagtgccag gtagattagt cggtcaaaca caagatgatg
     3001 aaggtaatcg tggctttgta ttaacattac aagcacgtga acaacatatt cgacgcgata
     3061 aagcgacatc taatatttgt tctaaccaag cattaaatgc tttagcgtca tcaattgcaa
     3121 tgtcagcact tggtaaacaa ggtatctatg atattgcagt tcaaaatata gaacatgcta
     3181 actatgctaa acaacaattt attaaaaaag gttttgaagt attagatggt acatctttca
     3241 atgagtttgt agtcaaattt gacaaaccaa ttcaacaagt taacgaggaa ttagtgaagt
     3301 acaatattat cggtggtttt gatttaggtg ttgtttcaga cgactttaaa aatcacatgt
     3361 taatagctgt aactgaatta agaacaaaag atgaaatcga tacatttgta gaaaaggctg
     3421 gtgagttaaa tgactagtaa atcaagtcca ttaatttttg aaagatctcg tgaaggcaga
     3481 tatgcatatt cattaccaaa aagtgatatt aaaacaaatt ctgttgagtc attgttagat
     3541 gataaattta ttcgtaaaaa caaagcggag tttcctgaag ttgctgaact agacttagta
     3601 cgtcattata ctgaactttc aaataaaaat ttcggtgtag acaacggatt ttatccattg
     3661 ggttcatgta cgatgaagta taatcctaaa attaatgaaa aggttgctag aataccagga
     3721 ttcagtgaat cacatccatt acaagatgaa gaccaagttc aaggttcatt agaaattatt
     3781 tatagtttgc aagaagaatt aaaagaaatt actggtatgg atgaggtaac attacaacca
     3841 gctgctggtg cacatggtga atggactgca ttgatgatat ttaaagctta tcatgagaat
     3901 aatggtgaag gtcatcgtga tgaagtcatt gtgccagatt ctgcgcatgg tacgaatcca
     3961 gcctcagctt catttgcagg atttaaatca gttactgtaa aatcaaacga acgtggcgaa
     4021 gttgatattg atgacttgaa acgtgttgta aatgaaaata cagcagctat tatgttaact
     4081 aatccaaata ctttaggtat tttcgaaaaa aacattatgg aaatccgtga aatcgtccat
     4141 aatgctggtg gtctattata ttatgatggt gcgaatttaa acgctattat ggacaaagtt
     4201 cgcccaggag atatgggatt tgatgctgtt catttaaact tgcataaaac atttactggt
     4261 ccacatggtg gcggcggtcc tggttcaggt ccagtcggtg tagtaaaaga actagcaagt
     4321 tacttaccaa agccaatggt tattaaagat ggcgacaaat ttaaatatga taatgacatt
     4381 aaaaattcta tcggacgtgt aaaaccattt tatggtaact ttggtattta cttaagagct
     4441 tatacgtata ttcgaactat gggagcaact ggacttaaag aggtttcgga agcagcggtt
     4501 cttaatgcga attatattaa agcacgttta tctgaacact ttgaaatacc ttataaacaa
     4561 tattgtaaac atgagtttgt gttaagtggt gtgcgtcaaa aagaatttgg tgtacgtact
     4621 ttagacatgg ctaagcgatt attagatttc ggtgtacatc caccaacaat atacttccca
     4681 ttaaatgttg aagaaggtat gatgattgaa ccgactgaga cagagtctaa agaaacactt
     4741 gattatttta tcgatacatt aattagtatt gctgaagaag ctaaaaatga tcctgataaa
     4801 gtgctagaag caccacatac aactgtgatt gatcgattag acgaagctac agctgctcgt
     4861 aaaccaatat taaagtttga aaatcttaaa caggaaaaat aaagtattaa acacatattc
     4921 cgagaattat tattctaact ttgtatgaag atttaaggat aatggtttca aaatcaattg
     4981 aaaaagacaa tttctatttg aacaagaaaa ataaaccgaa gtaataactc ttagggtttg
     5041 gtattattct ttcatagaaa ttgtcttttc attttttaga ttgcggtaat tgaatcgtat
     5101 tgaaaatgag ctgaactttc tttattatgc tgaaactaag tttaatgatc agtgaagcta
     5161 gagaaatata gtaacaggct ttgttaaaaa attaaaatct gagtattgtt attgatgatc
     5221 aattaacact cagattttat taaatcgtat attaaattta caaaaactat tttttagact
     5281 ttatttttcc agtccatttt ttatagccgc cttttaacat atagatatct gtatatccat
     5341 tctttttcaa aatacgagcg gctctatagc tagcaatccc attggcatca cataagtata
     5401 ccggttgatc ttttcttaat ccttggaatc gttgcctgaa cattgtcata ggaatattgc
     5461 gagacccatt aatgtgaccg tagtcatagt caactttctc tctaacatcg atgacttgag
     5521 cttttctaat cccattatgg aattcatttt gatctaattc tttaacagct cgcttgttaa
     5581 gaatttgttg aacaatcata taagcaataa ttgctataac taaaattatt gcgatgtaca
     5641 aactagcact catcttgcat cctccctaat taaacgataa tataattata agactgttag
     5701 gtcaaattat caaaatattt cactaaagaa ttgcaattat tattcattta gttaaattga
     5761 ttaattagcg aatcaaatat tatacatttt gctgatagga gttcttgaat atgactgaaa
     5821 cttggaattt tattaataca ggaagtaaag acccatatta taatatggca atggatgaag
     5881 cgttattaaa ttttgtctct agaggtgaaa ttgatccagt tatacgtttt tacacatgga
     5941 atcctgcaac attatcaata gggtatttcc aaaggctaca aaaagaaatt gatattgata
     6001 aggttaaaga gaaaggtttt ggtctcgtaa ggcgtcaaac tggtggccgt ggggtgctac
     6061 atgataaaga gttaacttac agtgtgattg tgcctgaatc gcatccgaat atgccttcta
     6121 cagttacaga agcgtacaga gtgatttcac aaggattatt agaaggattt aaaaacttag
     6181 gatttgatac ttattttgcg gtacctaaaa cgcctgaaga gcgtcaaaaa ttaaaacaac
     6241 ctcgaagttc agtgtgtttt gatgcaccaa gttggtatga gctagttgtt gaaggccgta
     6301 agattgctgg gagtgctcaa acgagacaaa agggcgtaat cctccaacac ggttcgattt
     6361 tacaagatat tgatattgat gaactgtttg atatgtttat ttataaaaat gaaagattaa
     6421 aattaaaaat gaaagaggca ttcgttgaaa aagcagttgc catcaatgat atttcagatg
     6481 aacacattac tattagtcaa atggaagaag ctttcgagaa aggttttaag aaaggtttaa
     6541 atatagaatt aaagccactt gaattaacag aagctcaatt ggcagaagtg gaagaattaa
     6601 ctgaaaaata tcgttcagat gaatggatgt ttagaaagta gtttttagaa taaaaaatgg
     6661 aagcacgtag actattttac ctacaagtgc ttccgttttt ttatctattt tcttctttga
     6721 tttcttttat acttacgcat tgctttgcga tatttgcgtt ggtcttcagt taagatgaag
     6781 aaataataaa tcagataaat aataccagct attacagcaa agctgattaa cattctgacg
     6841 attgaaaaaa taaaggcatc tagattcatt actaatccaa tcgcagcaat aataagtaca
     6901 agataaaata ttatattacg cattaaaaga ctcctatcat gattttgcat ttaagtttaa
     6961 ttttgacaac gcttgttgtc cttttgtaag ttgtttttta tctttatttt gatagccatt
     7021 tttaatatca tcaaatgcat gattcaaatc agagtttaat ttatcgatat ttttagacgt
     7081 ttttttatca tcatcactaa gtgataaacc atcgatagca tctttgtatg aagtgtgagc
     7141 actttgaata tcattagaaa tttgatttaa tttcgattga acattcttat cgcctttgtt
     7201 tttacttaca tctttctcaa tatcgttata ggatttcaaa gctttagcaa ctttgtcgta
     7261 gtatgttgat gtaacattca tcaatttaat tttcgtatta ttagatgcag tttttttact
     7321 gttttcttta tccttttcaa gccctttaat tttagattta gaatcactaa tttgttgatt
     7381 aagttcttga atatctagtt tgagttgatg attatcttct cttaaatctg ttgttttttc
     7441 ttctaatggt gctaaatttt gtgatccaca tccagctaac aataatgttg cgccaacaat
     7501 tgaaaccaat tttttcatta ctatctccct aaaatcaata tctattattt tttatcctta
     7561 ttatgatatt attttaatgt ataaagttga aatgcacaaa cgtttcacta ggaggtaata
     7621 agatgagcag aataacacaa gtgcatcgta ttttagaaca aaaacattta gatgcgatta
     7681 tcattctttc ggattacaat agaagatatt tatcaggttt tactggtacc agtggagcac
     7741 ttatcatatc taaagataaa caatatttga taacagactt tagatatatt gatcaagcaa
     7801 ctaagcaggc gccaaattat gaaattatta atcgtaaatc tactattatt ggtgagatta
     7861 aagaattgct acaccaagaa aattttgaaa atataggttt tgaggggcat catgtaagtt
     7921 atgatacata ccttgaatta aataaaagcc gtatatcatt aataagcatt tctaatactg
     7981 tagataaaat tagagacgtc aaagatgttg acgaaattgc tttaattcaa aaagcagcta
     8041 atattgttga tgaaacatat gaatatattt taactgttgt aaaagcaggt atgactgaaa
     8101 aagaattaaa ggcaatatta gaaagtaaaa tgctagaatt aggagcagat ggaccatcat
     8161 ttgatacgat tgtagcatct ggtcatagag gtgcattacc acatggtgtt gcaagtgata
     8221 aaattattga aaaaggcgac atgattacat tagattttgg cgcgtattat aacggctatt
     8281 gttcagatat tactagaaca tttgctattg gagaaccaga tcctaaactg aaagaaatat
     8341 atcaaatagt acttgaatct caaatgaaag caattaatga gattagacct ggcatgactg
     8401 gtgcagaagc tgatgccatt tcaagaaact atttagagtc aaaagggtat ggaaaagaat
     8461 ttggacattc actaggacat ggtattggtt tagaaatcca tgaagggcca atgctggctc
     8521 gtacgataca agataaactt caagttaaca actgtgttac agtagaacct ggtgtttata
     8581 tagaaggttt gggcggtata agaatagaag atgatatttt aattacagaa aatggttgtc
     8641 aagtctttac taaatgcaca aaagacctta tagttttaac ataagcgtgt aaaatgagga
     8701 ggaaactgaa tgatttcggt taatgatttt aaaacaggtt taacaatttc tgttgataac
     8761 gctatttgga aagttataga cttccaacat gtaaagcctg gtaaaggttc agcattcgtt
     8821 cgttcaaaat tacgtaattt aagaactggt gcaattcaag agaaaacgtt tagagctggt
     8881 gaaaaagttg aaccagcaat gattgaaaat cgtcgcatgc aatatttata tgctgacgaa
     8941 gataatcatg tatttatgga taatgaaagc tttgaacaaa cagaactttc aagtgattac
     9001 ttaaaagaag aattgaatta cttaaaagaa ggtatggaag tacaaattca aacatacgaa
     9061 ggtgaaacta tcggtgttga attacctaaa actgttgaat taacagtaac tgaaacagaa
     9121 cctggtatta aaggtgatac tgcaactggt gccactaaat cggcaactgt tgaaactggt
     9181 tatacattaa atgtaccttt atttgtaaac gaaggtgacg ttttaattat caacactggt
     9241 gatggaagct acatttcaag aggataatct ctaatttgtt aacaaatagc ttgtattcac
     9301 tatactgatt taacgtaaga tattctaaat aagtctcata aagctattgc ctaaaatgat
     9361 tataggttat atgctgatat gaggcttttt atttttaaaa taatttttaa aatataaaac
     9421 gaatcgtcta attggtagtg aaaaaacata gacatgagta aaggtatata tctacatatc
     9481 atattgttga ggataaaaca taatagctaa taaaaataac attgatatgt ttaactgaat
     9541 gcataaaatt tttaatcaag agttaagatg agtcaatgtt aagtaataaa tacacaagtg
     9601 tttttaattt aaaatgtggt tttattataa ctttgggata gacttataat gtcgccagca
     9661 atatgaacat gcttgaattg aagagttgtc tcaagtaaaa tagacgggta gatgaaaaca
     9721 aactgaagga gtcagtaata atgaacttta aagaaatcaa agaattaatt gaaattctgg
     9781 ataaatcaac tttaacggaa atcaatattg aagatactaa aggcaaagtg acgcttaaga
     9841 aagaaaaaga aactgagatt atcacgccac aaatctcaca aatgccagtt gaagctgcgg
     9901 caatgcctat gcctcaagca caatcaactg atagcaataa aactgaagct ccaaagccaa
     9961 cttcagataa tcacaaaaca attaatgcac ctatggtagg tacattttac aaatcgccat
    10021 ctccagacga agaagcatat gtgcaagttg gggacactgt ttcaaatgaa acaacagtgt
    10081 gtattttaga ggcaatgaaa ctatttaatg aaattcaagc agaaatttca ggtgaaattg
    10141 ttgaaatctt agtagaagac ggacaaatgg tagagtatgg ccaaccgtta tttaaggtga
    10201 aataatgaaa aaggttttaa ttgcaaaccg cggtgaaatc gcagttagga ttattcgcgc
    10261 ttgtcgtgat ttaggcatcc aaactgttgc aatctattct gaaggggata aagatgcgct
    10321 acatactcaa attgctgatg aagcatattg cgtaggtccc actttgtcta aagattcata
    10381 tttaaatatt ccgaacatct tatctattgc aacttctaca ggttgtgatg gcgttcatcc
    10441 gggttatggc tttttagctg aaaatgctga ctttgcagaa ttatgcgaag catgccaatt
    10501 gaagttcatt ggaccaagtt atcaatctat ccaaaaaatg ggtatcaaag atgttgctaa
    10561 ggcagaaatg atcaaagcca atgttccagt tgttcctggt agtgacggtt taatgaaaga
    10621 cgtctcagaa gctaagaaaa tcgctaagaa aattggctat ccggtcatca ttaaagctac
    10681 tgctggtggt ggcggaaaag gtatccgtgt tgctcgtgat gaaaaagaac ttgaaactgg
    10741 cttccgaatg acagaacaag aagctcaaac tgcatttggt aatggtggac tttatatgga
    10801 gaaattcatc gaaaacttcc gccatattga aatccaaatt gttggggaca gctatggtaa
    10861 tgtaattcat ttaggagaac gtgattgtac aattcaaaga cgtatgcaga aattagtgga
    10921 agaagcacct tccccaattt tagatgatga aacacgtcgt gaaatgggaa atgccgcagt
    10981 tcgtgcagcg aaagctgtaa attatgaaaa tgcgggaaca attgagttta tatatgattt
    11041 aaatgataat aaattttatt ttatggaaat gaatacacgt attcaagtag aacatcctgt
    11101 aactgaaatg gtaacaggaa ttgatttagt taaattacaa ttacaagttg ctatgggtga
    11161 cgtgttaccg tataaacaag aagatattaa attaacagga cacgcaattg aatttagaat
    11221 taatgctgaa aatccttaca agaactttat gccatcacca ggtaaaattg agcaatatct
    11281 tgcaccaggt ggatatggtg ttcgaataga gtcagcatgt tatactaatt atacgatacc
    11341 gccatattat gattcgatgg tagcgaaatt aatcatacat gaaccgacac gagatgaagc
    11401 gattatggct ggcattcgtg cattaagtga atttgtggtt cttggtattg atacaactat
    11461 tccattccat attaaattat tgaataacga tatatttaga agcggtaaat ttaatacaaa
    11521 ctttttagag caaaatagca ttatgaatga tgaaggttaa taggaggtca atccatggtc
    11581 aaagtaactg attattcaaa ttcaaaatta ggtaaagtag aaatagcgcc agaagtgcta
    11641 tctgttattg caagtatagc tacttcggaa gtcgaaggca tcactggcca ttttgctgaa
    11701 ttaaaagaaa caaatttaga aaaagttagt cgtaaaaatt taagccgtga tttaaaaatc
    11761 gagagtaaag aagatggcat atatatagat gtatattgtg cattaaaaca tggtgttaat
    11821 atttcaaaaa ctgcaaacaa aattcaaacg tcaattttta attcaatttc taatatgaca
    11881 gcgatagaac ctaagcaaat taatattcac attacacaaa tcgttattga aaagtaatgt
    11941 catacctaat tcagtaatta aataaagaaa aatacaaacg tttgaaggag ttaaaaatga
    12001 gtcgtaaaga atcccgagtg caagcttttc aaactttatt tcaattagaa atgaaggaca
    12061 gtgatttaac gataaatgaa gcgataagtt ttattaaaga cgataatcca gatttagact
    12121 ttgaatttat tcattggcta gtttctggcg ttaaagatca cgaacctgta ttagacgaga
    12181 caattagtcc ttatttaaaa gattggacta ttgcacgttt attaaaaacg gatcgtatta
    12241 ttttaagaat ggcaacatat gaaatattac acagtgatac acctgctaaa gtcgtaatga
    12301 atgaagcagt tgaattaaca aaacaattca gtgatgatga tcattataaa tttataaatg
    12361 gtgtattgag taatataaaa aaataaaatt gagtgatgtt atatgtcaga ttatttaagt
    12421 gtttcagctt taacgaaata tattaaatat aaatttgatc aagatccaca tctccaatct
    12481 gtattgatta aaggtgagct ttcaaatttc aaaaagcatt caagtggtca tttatacttt
    12541 aatgtgaaag ataaagagag cgttataagt gccatgatgt tcaaaggtag tgcttctaaa
    12601 ttaaacttcg aacctaaaga aggagatgaa gtcttattag aagcacgtgt ttctgttttt
    12661 gaacgtcgtg gaaactatca aatttatgta aataaaatgc aattagatgg tatagggaac
    12721 ttatatcaaa aattagaagc attaaagaaa aaattaactg aagaaggttg ttttgataaa
    12781 gcgaataaga aatcaatacc taagtttcct aaaaaaattg cagttttaac agcgagtaca
    12841 ggtgccgcaa ttcgagatat ccattcaacg ataaatagtc gttttccatt agctgaacaa
    12901 atacaaatta gtactttggt tcaaggtgaa aaagcaaaag acgacattat tgaaaaaatt
    12961 gaatatgcag atagtttagg tgtagatacc attattgtag gtcgaggtgg tggatccata
    13021 gaagatttat ggaatttcaa cgaagaagct gtcgtccgtg caatatataa ttgtaagaca
    13081 ccgattatat cagcagtagg tcatgaaaca gactttacat taagtgattt tgctgcagac
    13141 atcagagctg cgactccaac tcaagctgct gttattgcaa caccagacca atatgaattg
    13201 ctgcaacaaa tacagcaata tcagtttaca ttgactcgtt tcatcaagaa acatttagaa
    13261 caacaacgta aacatgttga acatttgtca tcgtattaca agtttaaaca accaacttta
    13321 ttgtatgatc aacagataca acgtcgagat gatttagaaa agagactgaa acaacaaatt
    13381 caggcaactt ttgaacaaca gagacatcga ttaatgctat tgcaacaacg ttataattta
    13441 aaagcattac taagtagtgt taatcaagaa caacaaaata atcttcaatt gacaaaccaa
    13501 cttgttaaat tattgaattc taagatatta agttataaaa atgatttgaa aaataaagta
    13561 gaaaacttaa acaatttaag tccaactaat acaatgttgc gtggatatgc aattgttaat
    13621 aaaaaagacg aagtcattac gagtactaaa gatttaacag aaaatgatca attgacgtta
    13681 acaatgaaag atggcttagt agatgcaaaa gttacgaaag taaggtgtaa taatgactaa
    13741 agaaacgcaa agttttgaag aaatgatgca agaattagag caaattgttc aaaaattaga
    13801 taatgaaaca gtatctttag aggaatcatt agatttatat caacgtggta tgaaactatc
    13861 agcagcttgt gacacaactt taaaaaatgc cgaaaaaaag gtgaatgact taataaaaga
    13921 agaagctgag gatgtaaaaa atgacgaatc taccgatgaa taaattaata gatgaagtca
    13981 ataatgaatt atcggttgcg ataaataaat cagtaatgga tactcagcta gaagaaagca
    14041 tgttgtattc attaaatgct ggaggtaaac gcatccgacc agttctgtta ttactcactt
    14101 tagattcact aaataccgag tatgagttag gtgtgaagag cgcaattgca ctagaaatga
    14161 ttcatacata ttcacttatt catgatgacc taccagcgat ggataatgat gattatcgac
    14221 gagggaaatt aacaaatcat aaagtatatg gtgagtggac tgcgatatta gcaggtgatg
    14281 ctttattaac taaagcattt gaacttattt caagtgatga tagattaact gatgaagtaa
    14341 aaataaaagt tctacaacgg ctgtcaatag caagtggtca tgttggaatg gtcggcggtc
    14401 aaatgttaga tatgcaaagc gaaggccaac caattgatct tgaaactttg gaaatgatac
    14461 acaaaacaaa aacaggagca ttattaactt ttgcggttat gagtgcagca gatatcgcta
    14521 atgtcgatga tgcaactaaa gaacatttag aaagttatag ttatcattta ggtatgatgt
    14581 tccagattaa agatgattta ttagactgct atggtgatga agcaaagtta ggtaaaaaag
    14641 tgggcagcga tcttgaaaat aataaaagta cgtacgtgag tttattaggg aaagatggcg
    14701 cagaagataa attgacttat catagagacg cagcagtgga tgaactaacg caaattgatg
    14761 aacaattcaa tacaaaacac ttattagaaa tcgttgattt attttatagc agggatcact
    14821 aaaagcaaat atatcgatta gcaacaattg taaagtttga aatgtctcaa aaggcatatt
    14881 caactgacgt tgtttgttaa tcgatttttc tcatgttgaa acttaaaatt atgttgaaga
    14941 ctttcattta aaaaatagaa ttttcaattt ctatacgaca atattcgtat ctgtgacatc
    15001 aatgtgattt taattaaata tgttcaaaca attgacgctt attaaatcta ataattagca
    15061 agtttattac acatatattc atttttatac atattttaag caattgttat gcgtaatatg
    15121 aaaaatattt ataaatagat aaccaagata gataaaccat gtttaccctt tttacgtaaa
    15181 ggtgtttagt agtcgtaaat cagtgcatgt gttaaaataa atgtataaat attcgtaatc
    15241 agaggtgttt actgtgccca aaaaatcggt taggcatata aaaattagag aaattatttc
    15301 aaatgaacag atagagacac aagatgaatt agttaaacga ttaaacgatt atgatttaaa
    15361 tgtcactcaa gcaactgttt ctcgtgatat taaagaacta caacttatta aagtacctat
    15421 accttcaggt caatatgttt atagtttacc aaatgataga aaattccatc ctttagaaaa
    15481 attgggacgt tatttaatgg attcctttgt taatatagat ggtactgata atttacttgt
    15541 tctaaaaaca ttacctggta atgcacaatc tattggagct atattagacc aaatcaattg
    15601 ggaagaagta ctaggcacaa tttgtggtga tgatacttgt ttaattattt gtcgaagcaa
    15661 agaggcaagt gatgaaatca agtcaagaat tttcaatttg ttataaggat gcgatgagtt
    15721 tatgttacaa accttatcaa tcaagcaatt tgctattatt gaagaattag aaattcaatt
    15781 ttctgatggt ttaactgttt taagtggtga aacgggttca ggtaagtcaa ttattataga
    15841 tgcaattgga caattaattg gaatgagagc ttcatctgat tttgtaagac atggtgaaaa
    15901 aaaggctgtc atcgaaggta tatttgatat tgacgagagt aaagatgcta tacatatatt
    15961 gaaaaatatg gatattgatg tagatgaaga ttttttatta gttaaacggg aaatttttag
    16021 ctctggtaaa agtctttgta aaattaataa tcaaacagtt actttacaag atttacgaaa
    16081 agttatgcaa gaattattag atattcatgg ccaacatgaa acgcagtctt tgttgaaaca
    16141 aaaataccat ttaacattat tggataatta cgcagaatca cgttatcaag atttgttgga
    16201 taaatatcac caaacttttc aaaattataa agccaaaaag caagagttag aagatttaga
    16261 atcagcagac caagcattgc tgcagcgttt agatttaatg aaattccaat tagaagaatt
    16321 gtctgaagca catctaaaag aaggcgaaat agagcaactt gaaatagata ttaaacgcat
    16381 tcaaaactct gaaaaattaa gcttagcgct taataacgca catatgacat taacggatga
    16441 aaatgctatc actgatcgtt tgtatgaact aagcaaccat ttgttaacaa taaacgatat
    16501 agttccaaat aaatatgaca aattaaaaga agatattgat caattttatt acattttaga
    16561 agatgcaaaa catgagttat atgatgaaat ggctaataca gaattcgacg aacaagtgtt
    16621 aaacgagtat gaatctcgta tgaatttgct gaataattta aaacgtaaat atggaaaaga
    16681 tatttcagaa ttaatcgcat atcaagaaaa gcttaataat gaaatcaata aaattgaaaa
    16741 ctatgaacaa agtacatcgc agttacgaga agaaataaat gcattgtata atcaagttat
    16801 agaggttgga caagcgttat caaagcagcg tcgtatagtc gctagggagt taagagacca
    16861 cattgtatcg gaaattcaaa acttacaaat gaaagacgca aatcttgaga tttcatttaa
    16921 aaaattagaa gaaccgaata ttgatggaat cgaatttgta gaatttttaa tcagtccaaa
    16981 taaaggggaa ccattaaaaa gtttaaataa aattgcatca ggtggagaac tttctagaat
    17041 tatgttagcg ttaaaaagta tttttgttaa atcgagaggt caaactgcaa ttttattcga
    17101 tgaggttgac tcaggtgtat ctggacaagc cgcacaaaaa atggcagaga aaatgcgaga
    17161 tatagcagaa tatatacaag ttatttgtat ttctcacttg ccacaagttg catcgatgag
    17221 cgaccatcat ttattaattt cgaagtcatc aaaagatgat cgtacaacaa cacaagttca
    17281 agagttaatt ggcgatgata aagtagatga aattgcacga atgatttcag gtgcaagtgt
    17341 tactgattta actcgagaaa atgcaagaga aatgatacaa cacaatcaaa gacgtagata
    17401 atttccaaag tgtgttgaat actcatttat ggatttattt atgtgcattc aaactaaata
    17461 gacaatcatg taaaataggt aattaatgga catgaaaact atgtattaat aaattttcaa
    17521 tggatatata tcattagtta ggagtaagaa catgtcagag aaacaatatg atttagtcgt
    17581 tctcggtgga ggtactgcag gatatgttgc tgcgatacgt gcgtctcaat taggtaagaa
    17641 agtggcaata gtagaacgac aactattagg aggtacttgt ctccataaag gttgtattcc
    17701 tactaaatcg ctgcttaaat ctgctgaagt atttcaaaca gtaaaacagg cagcaatgtt
    17761 tggcgttgat gtcaaagatg ctaatgttaa ttttgaaaat atgttggcac gaaaagaaga
    17821 cattattaat caaatgtatc aaggtgtaaa gcatttaatg caacacaatc acattgacat
    17881 ttataatggc acgggacgta ttctaggtac atctatattt tcacctcaaa gtggcacaat
    17941 ttctgtcgaa tatgaagatg gtgaatcaga cttattaccc aaccaatttg tattaattgc
    18001 aactggttct tcgcctgcag agttgccatt cttatcattt gatcatgata aaattttatc
    18061 tagcgatgat atattatcat taaagacgtt accatcaagt attggtatta ttggtggtgg
    18121 tgttatcgga atggaatttg catcattgat gatagattta ggtgttgacg taacagttat
    18181 agaagcaggt gaaagaattt taccaactga aagtaaacaa gcttcacaac tattaaaaaa
    18241 atcattgtca gcacgtggtg ttaaattcta tgagggaata aaactttctg aaaatgatat
    18301 aaatgttaac gaagatggtg ttacgtttga aatttcttca gacataatta aagtagataa
    18361 agtgttgcta tcgattggta gaaaacctaa cacatcagat attggtttaa acaacactaa
    18421 aataaaactt tctacatcag gacatatttt aacgaacgaa tttcaacaaa ctgaagataa
    18481 acatatttat gcagctggtg attgtatagg aaaattacaa ttggcacatg ttggatcaaa
    18541 agaaggtgtt gtggctgttg atcatatgtt tgaggggaac ccaatcccag taaactataa
    18601 catgatgcct aagtgtattt attcacaacc tgaaattgct tctatcggtt taaacattga
    18661 acaagcaaag gcagagggaa tgaaagttaa aagttttaaa gtaccattta aagcaattgg
    18721 taaagcagtg attgatagcc atgacgcaaa cgaagggtat agcgaaatgg tgattgatca
    18781 atcaactgaa gaaattgtgg gtattaatat gattggtcca catgtaacag aattgattaa
    18841 tgaggcatca ctgttacagt tcatgaatgg ctcggcatta gaattaggac taacaacaca
    18901 cgcacatcct tccatctctg aagtgttgat ggaattagga ttgaaagcag aaagtagagc
    18961 tattcacgta taaataggag gatttaacat gattgattat aaatcattag gccttagcga
    19021 agaagaccta aaagtaatat ataaatggat ggatttaggt agaaaaatag atgaaagact
    19081 gtggttattg aaccgtgcag gtaaaattcc atttgttgta agtggtcaag gacaagaagc
    19141 aactcagatt gggatggcat acgcattaga agaaggtgat attacagcgc cttattatag
    19201 agatctagct ttcgttactt atatgggtat ctcagcgtat gatacgtttt tatcagcgtt
    19261 tggaaagaaa gacgatgtta actctggtgg aaaacaaatg ccatcacact ttagtagtag
    19321 agctaagaat attttgtctc aaagttcacc ggtagcaact caaatacccc atgctgttgg
    19381 tgctgcttta gctttaaaaa tggatggtaa gaagaaaatt gcaacagcaa ctgttggtga
    19441 aggtagctca aaccaaggtg acttccatga aggtttaaac ttcgcgggtg tacacaaact
    19501 tccttttgta tgtgtcatta taaataataa atatgcaatt tcagtacctg attcattaca
    19561 atacgcagct gaaaaattat cggatagagc acttggttac ggtatacatg gtgaacaagt
    19621 agatggtaat gatccattag caatgtataa agcgatgaaa gaagcaagag atcgagctat
    19681 ttctggtcaa ggttcaactt tgattgaagc agtaacaagt cgtatgacag ctcattcatc
    19741 agatgatgac gaccaatatc gtacgaaaga agagcgtgaa gcgcttaaaa aagctgactg
    19801 caatgaaaag ttcaaaaaag agttgctttc agctggcatt atcgatgatg cttggttggc
    19861 agaaatagaa gcggagcata aagacatcat caataaagcg acaaaggctg ctgaagacgc
    19921 gccatatcca agtgtcgaag aagcctatgc atttgtgtac gaagaaggga gtcttaacta
    19981 atggctaaat tatcttattt agaggcgata cgccaggcac aagacttagc attacaacaa
    20041 aataaagatg tgtttattct tggtgaagat gttggtaaaa aaggtggcgt atttggtact
    20101 actcaaggac tacaacaaca atatggtgaa gacagagtta tcgatacgcc attagctgag
    20161 tcaaatattg ttggaactgc cattggtgca gctatggtag gtaaaagacc aattgcagaa
    20221 attcaatttg cagattttat tttacctgcg acaaatcaaa ttattagtga agctgcgaaa
    20281 atgcgttatc gttcaaataa tgattggcaa tgcccattaa cgattcgtgc accatttggt
    20341 ggcggtgttc acggaggact atatcattca caaagtattg aaagtatatt tgcttcatca
    20401 ccaggtttaa caattgttat tccttccaca ccgtatgatg ctaaagggct tttattatca
    20461 tctatcgaat caaatgatcc agtattgtac tttgagcata aaaaagctta tcgtttctta
    20521 aaggaagaag tgccagaaga atattacact gtacctttag gaaaagcaga tgttaaacgt
    20581 gaaggtgaag atttaacagt attttgttat ggattaatgg tcaattattg tttacaagca
    20641 gcggatattt tagctgcaga cggtatcaac gttgaagtcg ttgatttacg aactgtttat
    20701 ccattagata aagaaacaat tattgatcgt gctaaaaata caggtaaagt tttacttgta
    20761 actgaagata atttagaagg tagtattatg tcagaagtgt cagcgattat tgcagagcat
    20821 tgcttgttcg atttagatgc accaatcatg cgtttagctg ctccagatgt accatctatg
    20881 ccattttctc ctgtattaga aaatgaaatt atgatgaatc cagaaaaaat cttaaataaa
    20941 atgcgtgaat tagcagaatt ctagggaggg aaagtcatgg aaataacaat gcctaagtta
    21001 ggtgagagtg ttcatgaagg taccattgaa caatggttag tttctgttgg tgatcatatt
    21061 gatgaatatg aaccattatg tgaagttatt acagataaag tgacagctga agtcccttcc
    21121 acgatatcag gaacaattac agaaatttta gttgaagcgg ggcagacagt agctattgat
    21181 acatttatct gtaaaattga aactgctgat gaaaagacaa atgaaacaac tgaagagata
    21241 caagcaaaag tggatgagca tactcagaaa tctactaaaa aagctagtgc aacagtggaa
    21301 cagacattta ctgctaaaca aaatcaacct cgtaataatg gtcgcttttc acctgttgta
    21361 tttaaactcg cttcagagca tgacattgat ttatcacaag ttgtaggtag tggatttgaa
    21421 ggtcgtgtaa ctaagaagga tataatgtca gttattgaaa atggtggtac cacagctcaa
    21481 tctgacaaac aagttcaaac aaaatcaaca tcagtagata catcaagtaa ccaatcatct
    21541 gaagacaata gtgaaaacag cacaatacca gtaaatggtg tgcgtaaagc aattgcgcaa
    21601 aatatggtta atagtgtaac agagattcca catgcatgga tgatgattga agtagatgct
    21661 acaaatcttg tgaatacgag aaatcattat aaaaacagct ttaaaaataa agaaggatat
    21721 aatctaacgt tctttgcttt ctttgtaaaa gctgtagcag atgctttaaa agcatatcct
    21781 ttattaaata gtagctggca aggaaatgaa attgtcttac ataaagacat taatatttca
    21841 attgctgttg ctgatgaaaa taaattatac gtacctgtga ttaagcatgc agacgaaaag
    21901 tcaatcaaag gtatagctag agaaattaat actttagcaa caaaagcgcg taataagcaa
    21961 ttgacaactg aagatatgca aggtggaaca tttacagtta ataatactgg tacatttggt
    22021 tcagtatcat caatggggat tataaatcac cctcaagcag cgatattaca agtagaatca
    22081 atcgttaaaa agccagtagt aattaatgat atgattgcaa ttcgaagtat ggtaaattta
    22141 tgtatttcaa tagatcatcg cattttagat ggtttacaaa ctggtaaatt tatgaatcat
    22201 attaaacagc gtatcgaaca gtatacttta gaaaatacaa atatatatta gtgataacat
    22261 ggatacatct atcgacaact tgttttatct tgttcttgtc gatggatgta tttttttggg
    22321 caataaaata tgtgcaataa attcaaaaaa agataaagaa caataatcaa catggttgaa
    22381 tgcatttttg cagtaaagtc aaaataatac atcatactgg aaacatatta atgaaaacag
    22441 gtgaacaaat tagtttccat gatattaagc acaataatgt ttggtatatt gttaaaattg
    22501 tgtctaaata ttggtgtgat tcagattagt ttattgaaca atatgttatt aattagtaga
    22561 atgaggatag tttaaatata aagggatagg tgattgaact tatggacatg aatttcgatt
    22621 tatacatgaa cggtgttgta gaacaagcaa ggaatgaaat tgaatctgcg ggatatgagc
    22681 aattaactac tgcagaagat gttgacaaag ttcttaaaca agatggtaca acactagtta
    22741 tgatcaattc tgtatgtggt tgtgcaggtg gtatcgcaag accagcagca tcacatgctt
    22801 tacattatga cgtattacct gatcgtctag tgacagtatt tgctggacaa gataaagaag
    22861 cgacacaaag agcgcgtgaa tacttcgaag gttatgcgcc ttcaagtccg tcatttgcat
    22921 tagtaaaaga tggaaagatt acagaaatga ttgaaagaca tcaaatcgaa ggtcatgatg
    22981 tgatgaacgt aattaatcaa ttacaaacat tattcaataa atattgtgaa gaaagataag
    23041 aggcgctaac ccatgttaaa gttaaatcct tacaagattg gatttagaac aataaaaaca
    23101 gcagtgggta tgactttagg tgtaattatt agtaagctgt taggtttaga taattatgct
    23161 tcaagcgcca tattagtcgt attatgtatt aaacatacaa aagtacattc gctacaagcg
    23221 attatttcaa gattagtatc atgtttttta gtattgtttt taggttcagc aatatttagt
    23281 ttattaggtc agagtccaat tgtactcggt attatcgtat tgttatttat accattaact
    23341 gtcgtattaa aagtacaaga aggtgtcatt acgagttgcg ttatattact tcatgttttt
    23401 aatgcaaaat caattgatgc acatttaatt gttaatgaaa cattattact gttaattgga
    23461 ctgagcattg catttacaat gaatttaatg atgccaagtt tagacaaaca actagacgaa
    23521 tacaaatgta aaattgagca acaaattgct gatattttta gtaaatatag ttatatttgt
    23581 gaaaaatatg aagataccat tgcgattgaa tttgaagtgt tacttttaaa tattaaaaag
    23641 gcgaagtcta tcgcgttccg agatgttaaa aatcattttg ttagaaacga aaattcatac
    23701 tatcattatt ttgatatgcg agaagagcaa gtggaattgt taatgagaat gaaaccgctc
    23761 atcgaaagta tctgtcataa agatccactt ttaaatgatg tttcgtcact gctgaaagaa
    23821 attggtctaa atgtgaatag taatgactat acagcaatgc gtttacacaa tttgtatgag
    23881 acgcgtttga aattggatga actgccattg ccaacaacac acaaagcgct taactcgaga
    23941 gcaagtatta ttcaaatatt aaatgaatta gaagaatatt tacaaatcaa atcgcaattt
    24001 ggttcattga aaatgcatag tgaagtagct taaaaaataa tccatccgta tgacccatgt
    24061 ttgaaagtaa tcgttgcaat acgataactt attaatacat gcgtttataa cggatggatt
    24121 tttaattgta tgattttgta taggtagttg agatatagtt tataaaattg gaatgatact
    24181 cgttaataac aatgctaata caactgatac aagcataacg ataatgataa ttcttaaaac
    24241 tttattttgc attttgtgtg cctccaaatg aataaccttt gtattaataa ttacgacata
    24301 agatataaaa cttttaactt gagacgatat aactagcaat catcattaag gaatataata
    24361 aaaaacatga gtaagtttgc ttatgtcatt ttcctcatta tacgatatct ttgaaaaatc
    24421 aatcaatata tttttgacaa agcttagttt gagttacaat aaatatatat aataaattga
    24481 aaataatatg acacaattta caagcctgat aaatctgtgt aacgtcaatt actgtaacat
    24541 tttatttcat caatttttac cgtttggcgt acttgaaaat tttgataaaa ggggttccat
    24601 tatgattaat gagcaaagat tacttaatac gtttttagaa cttgtacaaa tcgattctga
    24661 gacagggaat gaatcaacaa tccaacctat tttaaaagaa aaattcatag cattagggtt
    24721 agatgttaaa gaagatgaag cggctaaaca tcctaaatta ggtgccaata atctagtgtg
    24781 tacaatgaat agtactatcg aagaaggcga agtacctaaa ttatatttga cgagccatat
    24841 ggatactgtt gtacccgcaa ttaatgtaaa gccaattgta aaagatgacg gctacatata
    24901 ctctgatggt acgactattc taggtgcaga tgataaagca ggattagcag cgatgcttga
    24961 agttttgcaa gtgataaagg aacaacaaat cccacatgga caaattcaat ttgtgattac
    25021 tgttggggaa gaatcaggtt taattggtgc taaagaatta aattcagagt tgttggacgc
    25081 ggactttggt tatgctattg atgcaagtgc tgatgtcggt actacggttg taggtgcacc
    25141 gacgcaaatg ttaatttcag ctaaaattat tggcaaaaca gctcatgcaa gtacgccaaa
    25201 agagggtgtt agtgctatta atattgcggc taaagcaatt agtcgaatga aattaggaca
    25261 agttgatgaa ataactactg ccaatattgg taagtttcat ggcggttcag ctacgaatat
    25321 tgttgcagat gaagtcattt tagaagcaga ggcacgttct cacgatccag aaagaataaa
    25381 aacacaagtc aaacatatga ctgatgtgtt tgaaactact gcatcagaat taggtgggaa
    25441 agcagaagtt acagtggagc aaagttatcc aggatttaaa attaatgata atgaagcggt
    25501 tgttaaaatt gcacaagaaa gtgctcgtaa tttaggatta tctgcaaata caattatttc
    25561 tggtggcggt tcagacggca gtattattaa tacatttggt attccttcag tcattttagg
    25621 agtgggttat gaaaaaatcc atacaacaaa tgagagaatg ccgattaaat cattgaactt
    25681 gcttgcaagt caagtgttag aaataatcaa aatagttgcg cgacaatcga aatgatttag
    25741 tgtagtgtat gtctattttg tgatacaata ctaatgaaaa atcaacaagt gaggtaagta
    25801 atatgacaca acaaattgga gttattggtt tagccgttat gggtaaaaac ctagcttgga
    25861 atattgaatc acgcggatat agtgtatctg tatttaaccg ctcaagtgaa aaaactgatt
    25921 taatggttga agaatcaaaa gggaaaaata ttcatccaac gtattcattg gaagaatttg
    25981 ttaattcttt agaaaaacca cgtaaaattt tattaatggt tcaagcaggt aaagctacgg
    26041 atgcaacaat tgatagtttg ttacctttat tagatgatgg agatatttta attgatggtg
    26101 gtaatacaaa ctatcaagat actatcagac gtaataaagc attagcacaa agtgcaatca
    26161 actttattgg tatgggcgtt tctggtggtg aaattggagc gttaactggt ccgtcattaa
    26221 tgccgggtgg acaagaagaa gcttataaca aagttgcaga tattcttgat gcaattgctg
    26281 ctaaggcaaa agacggtgct tcatgtgtta cttatattgg accaaatggt gctggacact
    26341 atgtgaaaat ggtacataat ggtattgaat atgctgacat gcaattaatt gcagaaagtt
    26401 atgctatgat gaaagaatta ttaggtatgt ctcatgaaga cattgctcaa acgttcaaag
    26461 actggaatgc tggtgaatta gaaagttatt taattgaaat cactggtgat attttcatga
    26521 aattagatga aaataaagaa gcattagttg aaaaaattct tgatactgca ggtcaaaaag
    26581 gtacaggaaa atggacttca attaatgcat tagaattagg tattccatta acaatcatta
    26641 ctgaatctgt atttgcacgt tttatctctt caatcaaaga agagcgcgta aatgcttcta
    26701 aagaattaaa tggtccaaaa gcatcatttg atggtgacaa gaaagacttt ttagaaaaaa
    26761 ttcgtaaagc attatatatg agtaaaattt gttcttatgc acaaggtttc gcgcaaatgc
    26821 gtaaagcaag tgaagataat gaatggaatt taaaacttgg tgatttagct atgatttgga
    26881 gagaaggttg cattatacgt gcacaattct tacaaaagat caaagatgct tacgataata
    26941 atccaggatt acaaaactta ttgctagatc cttactttaa aaacatcgtt actgaatatc
    27001 aagatgcgtt acgtgatgtt gtcgcaactg gtgttcaaaa tggtgtacca acacctggtt
    27061 tctcatcaag tattaattac tatgatagtt accgtgcagc tgatttacct gcaaacttaa
    27121 ttcaagcaca acgtgactac ttcggtgctc acacgtacga aagaaaagat aaagaaggcg
    27181 tattccatac acaatggatt gaagaataat attgaccatt gagcctgaga ccttatgaat
    27241 ttaggtaatg ttaaagagac aatttctatt atttatttga tagaaattgt ctctttcctt
    27301 atgtatttat cgaaattttc tacgcatgat atattcaatg attttctttc tcttgtcaaa
    27361 ttaaaatttt caacttttat aaattaacga tatctatcct catagaattt gtccgtttaa
    27421 gtgtagacgt tttacttaca tactattaag atagcattag taaataattt taatatttcg
    27481 ataaatagat tacgttttat tatttgatga ataagaggga tagaatgtca tatacttctg
    27541 tattgtttaa taagaacttt actttttatt taatagggat agctttttct aacatgggca
    27601 gtgcttttac tacgtttgtt tttccattaa tgattttaaa gcttactgga tctgcatttc
    27661 aagttggcat agtttctgca ctaagtttta taccttatgc aattttagga ttgccagctg
    27721 gtgctttaat tgacagattg aataagaaga ccataatgaa atgtgctgat ataattaggt
    27781 tcgtttcata tttaagtata ccagtattaa gttttttcaa tatgttaagc atctttcaaa
    27841 tttatgtagt tgcaatcatt tcaggtattg gattagtatt tcacagtatt tctgaggttt
    27901 cgataatccc aagtattgta aaagaagaag atttggcgag cgcaaacagt tatatatacg
    27961 ctactcaaaa tgtttcggaa tttttgggcc ctataattgg aggtttactt tatacatata
    28021 tgggatattc aatattgatt tttatagatt ctatgacttt tttactctca tttttcagtt
    28081 tgatattaat taaaattgaa acaaagagta tattcaatca agaaaagttg agtggaaaaa
    28141 attttttgag cgatgttaaa gttggatttg attatctatt atctaattca actattagag
    28201 taatggctgt tgttgtaagt ttatccaatc taattatctc accttattat atttatatag
    28261 taatgtttgt aaaggaagac atgaatcaat catctcaagc attggggtta gttttaggta
    28321 tctcatcatt aggtgcgcta atcggttcat tatctgcaag ttttctcttg aaattattta
    28381 atttcggaaa actaattgta attatattat ttttagatac aatttttaga ttaatgttac
    28441 catttagtac ttatattttt atactcatcc cacttttagg gttgacatat atgacacaat
    28501 ccattttaaa tatagcgata atcacactga ggcaaaagaa atgttcagaa aatatgttag
    28561 gacgtgttaa tagtgttttt aaaacaatgg tttttgcatt cagacctata ggcctttttt
    28621 taggcggtat attacttgaa aataaaggtg gattttatgc acttacgatc agtgctgtgt
    28681 tatttatacc attagtgtta tatatactga aaaatagatt ttatcaagtt gaagaatatt
    28741 aagaagaaaa ttaataaaaa tggctgctat gtcaaattgg actgatgaat tcaatatagg
    28801 aagttaggca actaaacatt gtataacttt ctttttagtt attggagctt aaagttttga
    28861 acataataat attcgattgc gcaaatgatt gtaacttcca taatcaaatg atgtacgttt
    28921 aattaatttt attatgttag ttatacattc taatggacaa tgtgagctac acccagttaa
    28981 gttgacatag aaaatacgaa aactttgaac gaagtatttc attgatatat gtcccagacg
    29041 acatgtttga ttaatgaagt tctatgtggc tacaaaattt taaaaattac acaagcaata
    29101 tctattacct taaaagcatc ccgccatatt tttaagcatt ttgtgaagta ataaaatatt
    29161 tactgtgtta tgatagcatg tactatagag aaatagaggt actattttat ggaaaagtta
    29221 aatcaagtta tgttatatgt tgatgatgtt gaaaaagcga aagcattttg gacagaaact
    29281 ttagaatttg ttgttgtaag tgaaacaccg ttagctgagg actatgttgc agttgaagta
    29341 tcacctacca aagatgctga aacgtcattg acgattatgg caaaagaatt tattgaaaag
    29401 catagtccag aggtgaacct aggaacacca tctttaatgt ttaaagagaa aaactttgat
    29461 gcattatact caaaattaaa tgatttaggt ttaactgggc atgatatagt agaaatggat
    29521 ggtcaacgtg tatttaattt ccaagatgga caaggtaatt attttgcagt tagtgactaa
    29581 acaatcgatt ttaatattta tacaaacctt tatattgatt ttcggattga atttcagtat
    29641 gaaggtttta tttttatcgt tttatgcaat cgtttgcaca aatcttttga cttttttaga
    29701 aagagtaact aaactgttat tatatagagg ttggaagcgt tttccaatgc agaaattaac
    29761 aggaggtgat taaatggtta cgattaaaga tgttgcacta aaagccggtg tttctccttc
    29821 gacagtttca agagttataa aaggaaataa acgtattagc gaagcgacaa tttcaaaagt
    29881 gaagaaagtt atggaagaat tgaattattt tcctaatacc gctgctagaa ctttaattac
    29941 aaaccaaaca tataaaattg gtttagtgtt aaaagggtct gaggagccta ttcgactgaa
    30001 tccattctac atcaatgtat tgctaggaat ttctgaaacg tgtaaccagc atggctatgg
    30061 tacacaaacg acagtctcaa ataatatgaa tgatttaatg gatgaagttt ataaaatgat
    30121 taaacaacga atggttgatg cgtttatact gctttattca aaagaaaatg atccaattaa
    30181 acaaatgtta attgatgaaa gcatgccatt tattgtgatt ggtaagccta catcggatat
    30241 agatcatcaa tttacacaca tagataatga taatatatta gcttctgaaa atttgacacg
    30301 acatgttatt gaacaaggtg tagatgaatt aatatttatt acagaaaaag gaaattttga
    30361 agtttcaaaa gatagaattc aaggatttga aacggttgca tcacaattta atctggatta
    30421 tcaaattatt gagactagta atgaaagaga agttatttta aattacatgc aaaatctaca
    30481 tacgcgtttg aaggacccaa atattaaaca ggcaatcatt tcgttagatg ctatgttaca
    30541 tttagcgatt ttaagtgtcc tatatgaact taatattgaa attccgaaag atgtaatgac
    30601 agcaacgttc aatgattctt atttaaccga aattgcgtca ccacctcaaa cctgtattga
    30661 catcaagcct cgaatgttag gtcaacaggc tggttcagca attttaaata tattgaaaaa
    30721 caaagcacag gatgttattg aactcgtcat tatagataca gaattaaaaa taagaaaatc
    30781 aacacagcga tagcaaagga gttttaaaat gaataagcaa tggtggaaag aagcagtagc
    30841 atatcaagta tatccaagaa gttttaatga tagtaatcac gatggtattg gggatttacc
    30901 tggaatgatt gataaattgg actacttaaa agatttaggt atcgatgtca tttggctcag
    30961 tccaatgttt aaatcaccta atgatgacaa tggttatgat attagtgact atcaagaaat
    31021 tatggatgaa tttggaacga tggaagactt tgattgttta ttaaaaggta ttcatgatag
    31081 aggcatgaag cttattttag atttagttgt aaatcataca tctgatgaac atccttggtt
    31141 tatagaatct aaatctagta aagacaatcc caaacgtgat tggtatattt ggcaagatcc
    31201 aaagccagat ggctctgaac ctaacaactg ggaaagtatc tttaatggat ctacatggga
    31261 atatgatgct aatactgagc aatattattt ccatttattc agtaaaaaac aacctgattt
    31321 gaattggggt aatccagaag ttagagatgc tgtatttgaa atgatgaact ggtggtttga
    31381 taaaggcatt gatggattta gagtagatgc aattacgcat attaagaaga cgtttgaagc
    31441 gggtgactta cctgtacctg agggtaaaac atatgcccca gcatttgatg tagatatgaa
    31501 tcagccaggt atacaaactt ggttacaaga gatgaaagat cgctcattaa gtaagtatga
    31561 cattatgact gtcggtgaag cgaatggtgt aagccctgat gatgctgatg actgggtcgg
    31621 ggaagaaaat ggtaaattta atatgatatt ccaatttgaa catttgggac tgtggaatag
    31681 tggtgattct cactttgatg taaattcgta taaatctgta ttaaatagat ggcaaaaaca
    31741 acttgaaaat aaaggttgga atgcgttgtt tattgaaaat cacgaccaac cacgacgtgt
    31801 atcgacgtgg ggtgacgatg acaagtattg gtatgaatca gcaacaagtc atgcagctgt
    31861 ttatttcttg caacaaggta cgccattcat ttatcaaggt caagaaattg gtatgacgaa
    31921 ttatccattt gaaagtattg aaacgtttaa cgatgttgct gtaaaaaatg actatcaaat
    31981 agtgaaagct caaggtggag atgtagacgc tttacttgcg aaatataaag atgagaaccg
    32041 agataattct cgcacaccaa tgcaatggga tgatacgtta aatggaggat ttacaaatgg
    32101 tgaaccgtgg ttcccagtga atctgaatta taaaactatc aatgttgcac aacaattaga
    32161 agatgagcat tcagtattac aattttataa agatttaatt caattaagaa agtctaatga
    32221 tgtatacgta tatggtcaat ttgatttagt agatgctgaa aattcacaag tttttgcgta
    32281 cacgagaaca ttaaatgaaa agcaagttct tattgtaggt aatcttacta accacgaagc
    32341 agaattaact gtaccatttg atttaagcca tggagaagta aagctattta attatgatgc
    32401 caaagttaat ttaaaacagt tacgtccata tgaagcatgt gttatcgaac taaattaaca
    32461 tattaatatg ccccctaata gaatctaagg ccatttgtag acctatagat ttattagggg
    32521 gcttctttgt ttttaatttt taatcttcgt cataaggact ctgtttaaca ggaatccaaa
    32581 gctgaatttt agtgaatggg tcattaaatg aaatatcgag agggtacact tcaacatata
    32641 aatcatttcg ttcatatggc aatgttaact gcaaacttga ttcaatatag taccaagctt
    32701 cattagttgc ataatcaatt tcaccttgta aattgaattt cgcacaatgt ttgccaggta
    32761 aaaatcggct ttctaagtgt gcaggataac gttcacttgg tacacctaca aatatttcta
    32821 aaccattttc aagaggacaa ctaataacaa atagttcaaa tggactaacg tcattatatc
    32881 gtcgtaactc tttaatttta ccatcaatga gcaagtcttc taaaaaatcc ggaacattaa
    32941 aaggatgtga caaatactta gtgtctataa atcgtgcata tccaaccaat gaaatatcat
    33001 ctgtctcttc taatctgtat ggatagggtg ctctctcagt agttgataat ttgatatata
    33061 atcgctcttg aatttgtaat tcatcttttt tagtagaagc ttgaataggt gatacgccgt
    33121 gaaaatcact aaaatcattt gcaaaatcat ttgaatttgc atagtgatat tttttagcga
    33181 tatctacaag tcgtgtagca ccattaatca catcatttgc agcgagtgtc attttacgcg
    33241 cgcgtgcata agcttctgga gataagccga caatcatttt aaatgattga tcaagatggt
    33301 atggcgaaag accaacgtaa tcacttaatt cttgcaaatt gaaaggctct aataaacgat
    33361 cttcaatata aacaattgcc tgttgtattt gcttgataac gtccaaaact ttcactccaa
    33421 ttaattcaat catttatttt tattctacat tatttctata aattatacac ccatttgttc
    33481 aatgattatt aaaatagttt tgggcattgt aaaatataat ttcataatat agtctagaaa
    33541 aaaagcgaat gatagaacaa ttgatttact tgattcgtaa tcaatccttg tcattcgctc
    33601 atttattttt gtttaacatg tgcgttttaa ttcaattatt gaatatcgtc ccaccaatgg
    33661 ttaccatcac gagcaagtag taaatcactt tctaatggac cattagtacc tgattcatag
    33721 ttagggaatt ctggatcaac catattccat tcatcttgaa ttgcatcaac aaatttccat
    33781 gttgatttta attcttccca gtgcgtgaag ttagtggcat cacctttaag acaatcgaat
    33841 aatagatttt catatgcatc tacagtattc attttatctt gagcgctcat tgaataagac
    33901 aattgaacag gttcagtttc gataccttgt gtatttttct tagcatttag atgtaaagat
    33961 acaccttcat taggttggat attgattact aataggtttg aatctaatag tttatcagtt
    34021 tcatagtata agttcattgg tacttcttta aattcaacga caacttgaat tgttttagat
    34081 ttcatacgtt taccagtacg aatatagaat ggtacaccag cccatctaaa gttatcaatt
    34141 gttaatttac ctgaaacaaa ggtaggtgtg ttagagtcat ctgcaacgcg atcttcatca
    34201 cggtatgctt taacttgttt accatcgata tagccttcgc catattgacc acgaacaaag
    34261 ttctttttaa catcttcaga ttggaaatga cgcagtgatt taagtacttt tactttctca
    34321 gcacggatat cttcactgtt taaactaata ggtgcttcca tagctaataa tgcaaccatt
    34381 tgtaacatgt ggttttgcac catatctttt agcgcgccac ttgattcata ataaccacca
    34441 cgatcttcaa cacctagtat ttcagaagat gtaacttgga tgtttgaaat atatttgtta
    34501 ttccataatg gttcaaacat cgcattcgca aaacgtaata cctcgatatt ttgaaccatg
    34561 tcttttccta aatagtggtc aatacgataa atttcttctt ctttaaatga tttacgaatt
    34621 tgattgttta atgcttcggc tgattttaaa tcactaccga atggtttttc gataacaagg
    34681 cgtttaaatc cttttgtatc agtaagacca gaagatttta gataatcaga aataacgcca
    34741 aagaattgtg gtgccattgc taaatagaat agtcgattac cttttaattc aaattggcta
    34801 tctaattcat tactaaaatc tagtaattct tgatagcttt cttcattact aacatcatgt
    34861 ctatgataga agacatgttc cataaacgcg tcaattttgt ttgtatcttt tacgtgcttt
    34921 tgaattgatg attttacttg attacggaaa tcatcattag taatgtcacg acgtccaata
    34981 ccgatgatgg caatatgttc atctaaattg tcttgttggt agagatggaa tattgatgga
    35041 aacaacttac gatggcttaa gtcaccagtt gcaccaaaga ttgtgattaa acaagggatg
    35101 tgtttgtttt tagtactcaa gattaaaacc tcaattctta attagatata tgatttatta
    35161 ttataagata atccattcag caggtcattc aatatgctcg acagtatgca gtgtcttaaa
    35221 tgaaatatcg attcatgtat catgtttaat gtgatactta ttaatgataa gtataacgta
    35281 attgtcaaaa tttatatagt tatgtctacg ttaaagttag aaaaattaac tagcaaagac
    35341 gaatttttaa cagattttga ttcaagtata aattaaaact aaattgatac aaattttatg
    35401 ataaaatgaa ttgaagaaaa ggaggggcat atatggaagt tacatttttt ggaacgagtg
    35461 caggtttgcc tacaaaagag agaaatacac aagcaatcgc cttaaattta gaaccatatt
    35521 ccaattccat atggcttttc gacgttggtg aaggtacaca gcaccaaatt ttacatcatg
    35581 caatcaaatt aggaaaagtg acacatatat ttattactca tatgcatggc gatcatattt
    35641 ttggtttgcc aggattactt tctagtcgtt cttttcaggg cggtgaacag aagccgctta
    35701 cattggttgg accaaaagga attaaagcat atgtggaaat gtctatgaat ttatcagagt
    35761 cacatttaaa ctatccaatt acatatattg aaatcgatga tcatctgaca tatcatcatg
    35821 atggttttac tgtagaggcg catttactta atcatggtat tccatcatat ggatatagag
    35881 taatggcacc tgaaactaca ggtacaatca atgttgaagc gttaaaaaac attggtcttg
    35941 aaccaggtcc taaatatcaa gaagtaaaat ctcatgatac atttgaacat aatggtcaag
    36001 tttatcaatc aaaagatttt agaggtgagt ccaaacaggg tccagttgta gcaatttttg
    36061 gtgatacaaa accatgttct aatgaacgtg tgatttctag agatgctgat gtgatggtac
    36121 atgaagcgac ctatatagat ggtgaaaagc atttagccaa caattatcat catagccata
    36181 ttgaagacgt atttgcattg ataaaagaag ccaatgttaa acgtacgttg attacacatt
    36241 tgagcaatcg ctataataca gaagatataa atgaaattta tcaaatattg atacaaaatg
    36301 aagatacacc taattttaat tttgtaaaag attttgatag ttttaaagtc taatgacaaa
    36361 gtaataaaca atgcttgcca aatagtaata atttataaaa ataacccgtc caactatgta
    36421 tgtgatgatg catacatgtg ttggcgggtt tgtttttatt ggtcttctac attagaaagt
    36481 tcaatactac ggtcgacggc agcatttaga caatcttcga aaatagatac taaatcatat
    36541 tgtgacaatg tatcaaggcc agcttgtgtc gtaccacctt tagaggtaat attttttctt
    36601 aattgagcca tgctcaaatc tgaacgttca atcatcttac ttgtacctat aataaggttg
    36661 cgtatagatt cttcaacttg ttctttttct agaccaagtt tcgtaccagc tttaacgtat
    36721 tgctcgaata catgatataa aaatgctggg ccgcttccgg tgatagctgt tacttgatgt
    36781 aaatgatcct ctgatacttc aattacagaa ccaaatgctt taactaaatc gttaatttca
    36841 tctttagatt tagggtcaaa gttgtttgaa aaactaatgc cagtaactga gtgtccaact
    36901 tgcgcatttg tgtttggcat aattctagca actggatttt ggcattctaa ttgttgttta
    36961 atataatcaa tcggaatacc tgccataatt gaaatgaagc aattgtcttt tgtgatatgt
    37021 ggtttgatgc gtgttgctag agcatcaaag tcatgcggtt tggtacctaa aaaaacataa
    37081 tctgcatctt ttaataatgt cgcatcatca taactatagt taacacctag tttttcagcg
    37141 aatgctttta aagcttgttc attagattta tttgttaaat atatatcatt ggcatctaag
    37201 ttgcttgagt taataattcc tgtaaatata gcttgtgcca tattaccagc tccataaaat
    37261 acgagtttca ttaacgtcac atccctttag tttttgattt gtatgttata ttttcttatt
    37321 attgtatata tattaggaaa gataatcaac ttgtctcaat tatacagaga cgataaattg
    37381 cattctatat aattgaaaag gaaggttaat tgatgaaagg acaacatttt atagtgactg
    37441 gtggtacgag tggtttaggt ttatcgattg tccgaaagtt actagaaaat aaagtgcatg
    37501 taacgttgtt ggtgcgtgat gttgataaag caactagaat ctttgaacaa gaattgggga
    37561 aaactataaa tgttattcct tgtgacttaa atgatttgaa gtcgatacag gcactgcaat
    37621 ttgaagacaa tacatcattc gatggattca tttatagtgc aggtttaggt tatttcaaat
    37681 ctatttcaga ccatagtttt tcagaaatga ttgaaacgta tcagcttaat ttaattagtt
    37741 ttaatgtttt atatactgtg ttgagaccat atttaacatc taacgcacat attgtaggta
    37801 tttcaagtca agctgcattt tccacacaag caaatgctgc acattatggg gcatcgaaag
    37861 cagggtttta tgcattaatg aatgctttaa gactagagtc accaaactta catatcatga
    37921 cagttaatgt tggcccgatt gatacacctt ttcatcaaaa agccgaccca tcaatgaagt
    37981 atgctaaaaa gatgggggaa attatgcttg atgctaatca gcttgcagaa gatatcattt
    38041 atggcattaa aacaaaacaa ttggaaatta atcggcctaa atggatgcat catgcgttga
    38101 aaatgtatca aattgcgcct agattttttg aacgatgttt ccctaaatta tttaaaaata
    38161 aagcataaat aggtgggatg gcaatgaact gtcaatcgga gagtgtggta agactttgtg
    38221 tacgatatgc ggaacaacta tcagtatttg aagaatttac agtgctggat attttaggcg
    38281 atatttctgt agaccaaatt tcagacggta cattatatta tacttgtgaa aaattcaaac
    38341 tacttgtgtt gcaaggaaat gtgctgggtg tacaaataat aactaataat gatgaatcaa
    38401 catgcgaagt gaaatataga aagatgtttt aataaaatta ttaagagatg aagtggcaga
    38461 agtttgctta aggcaatgcc gcaaggcgaa attactaaat actgatgcgt gaggacaacg
    38521 ctttaatttc tatcataagt gagtaatcat aatcataaat tatagcgaat tgtacataaa
    38581 caacagcagt aaggcatttt tataatgaaa cgcctcatgc tgctgttttt attactgaaa
    38641 atgacttcta cactaaatga ttggtatatt ccaaatcctt tacacgagct cttgctgttt
    38701 taatctgatc taaaccaact ttagtatgat agttttcaat attttctttt aattggtcga
    38761 cgctacttgc acctacaatg atggaaccaa gcacgtcatg tgatgttaaa taactaaatg
    38821 tcaatgcaga taaattactt tcaatttctt taatagaggc tattgtttca cccaattcat
    38881 catgagaata atcaaaaata ccatctttaa atttattgtc gagcacatta acactgtttg
    38941 aagttaataa tcctttagac acaggtcctc ttgccaatac tttaacatca ttgttgtgaa
    39001 ttgcatctaa taatgattct ggacgattat caatcaaatt gaattgagac attatcgttt
    39061 cgatttgact atgttttaaa taataatcaa ttacatttgg gcgaatagaa gaaataccgt
    39121 aagcacgtat aattccttct tgtttcaatt catcaaatgc gcttattgtt tcgtctaatg
    39181 ggtcatcaat ggttccgcca tgaagttgat ataaatcgat atgatcgata cctaaacgct
    39241 ttagtgaacc tttaactgcc tctttaatat aggatttact cggatcccat gttgtactgc
    39301 catcttttgt taaacgattg cctacttttg taccaatgaa aatatcatcg cgttgttgat
    39361 atttaagaag tgccttacca acaactgatt catttatacc tttatcgtac atgtctgctg
    39421 tatcaaaata agtgatacca ttttcaacag cacaatctat aatttgttcg gcttttttta
    39481 aatctgtacc taaactcatg caacctagac ctaattcaga taatgcaata ccacttttta
    39541 atatattttt tgcatgtctg ttctcctttc gatacacttt agctaacaag catagtgtat
    39601 caatatataa tatgaattta aaggaacgtg attataatgg atttaaatga aaaaacaatt
    39661 gatcgaacag ttatttataa tggcaaaatt gtagatgtag aaattcatac agtgacatta
    39721 ccaaacggtg aaacgtcaac aagagaatta gtttatcata atggtgcagt tgctgtttgt
    39781 gcattgacac ctaaaaaaga agtcgtatta gtgaaacagt atcgtaaacc agtagaaaaa
    39841 ccattgctag aaattccagc tggtaaatta gaagatgatg aaaatagagt cgaagcggct
    39901 aagcgtgaat tagaagaaga aacaggatat attgccaaag agttaacaca tgttgtagat
    39961 atgtatggtt caccaggttt ttgcgatgaa caattatcaa tttattttac tgataattta
    40021 gaagaaggta cagttcactt agatgaagat gaatttgtcg aagtcattaa agttccgatt
    40081 gagaatgtta aatcgatgct aatgaataaa gaaatagaag atgcgaagac tatcattgca
    40141 ttgcaacacc tattattaaa ttataatcat tctaaataac aaatgagaaa agcttgcatt
    40201 ttattgagaa aactgttagt tttaattgtg aagtttgaaa taatttgtaa tgattttaat
    40261 tattagtagg ggagtggaca tcgttggaag aacgattaaa tcgcgttaag caacaattac
    40321 aacaatcatc atataagcta acgccacaac gcgaagctac tgttagagtt ctaattgaaa
    40381 atgaaaaaga tcatctaagt gctgaagacg tatatctgaa agtaaaagac aaagcgcctg
    40441 aaattggctt ggcgacagta tacagaacgt tagagttgtt agctgaacta aaagttgtcg
    40501 acaaaattaa ctttggtgat ggcgtcgctc gttttgattt aagaaaagaa ggcgcaaaac
    40561 atttccacca tcatttagta tgtatggaat gtggtcgtgt agatgaaatc gatgaagatt
    40621 tgttaccaga agttgaaaat cgagttgaaa atgagttcaa ttttaaaatt ttagatcatc
    40681 gtttaacttt ccatggtgtg tgtgaaacat gccaagctaa aggtaaagga tagtaaattg
    40741 cgtaggttaa attaaccttc gcttttttta gaggtgtggt tatggaaaca attattgaag
    40801 aatatttgcg ttttatacaa attgaaaaag gactaagttc taacacaatt ggtgcttata
    40861 gacgtgattt gaaaaagtat caagattata tgactgaaca tcatatctcg catattgatt
    40921 ttatagatcg acaattaatt caagagtgtt tggggcattt aatagaccaa gggcaatctg
    40981 ctaaatctat tgcgcgattt atttcaacaa tccgtagttt tcatcaattt gctataagag
    41041 aaaaatatgc ggcgaaagat ccaacggtat tattagattc accaaaatat gacaaaaaat
    41101 tgcctgacgt tttaaatgtt gacgaagtat tggctttatt agaaacgcca gatttaaata
    41161 aaattaatgg atatcgtgat cgtacgatgt tagaacttct gtacgcaacg ggaatgcgtg
    41221 tatctgaatt gatacattta gagttagaaa acgtgaactt aataatggga tttgtacgcg
    41281 tatttggtaa aggcgataaa gaaagaattg taccattagg cgacgcagtc attgagtact
    41341 taactactta tattgaaacg attagaccgc aacttttaaa aaagactgtt actgaagtct
    41401 tatttttaaa tatgcatggt aaacctttat cacgacaagc aatatggaaa atgattaaac
    41461 aaaatggcgt aaaggcaaac attaaaaaga cgttaacgcc acatacgtta cgccactctt
    41521 ttgcgacaca tttattggaa aatggcgcag atttaagagc agtgcaagag atgttaggtc
    41581 actctgacat atctactacc caactctata cacatgtttc gaaatctcaa attagaaaaa
    41641 tgtataacca atttcatcct agagcataaa gtgaaccata acttaaaagt cacaatacac
    41701 atgactaaaa atgtctgtgc tattgtggct tttttaaatt ggttgattaa ttacgtctat
    41761 gttttcttaa ttgaatcgct tcttcttttg ctgcaatcac ttctgaacga tcacgccgca
    41821 tgtgatggtc tacaataaaa ggatctgttg ctgtttcctg attataatca tagtctggat
    41881 agttggcctt gatgatgcgt tcaaagactg gagttattgg taatataaca gatgaaaaag
    41941 gctttgctgc attcaatttt gcaatctgtt gctcaattaa caattgataa tcatttaaat
    42001 taaggtataa cgcatctcta tctttagcat tttgtattat ttctttagat ttattaaaag
    42061 acttataggc gccttttaaa ttattgcggc gataatggta acaagcagtt gcaaacaaga
    42121 ttaaactaac aactgcatct tgcttactgt agttattttc agctttccat gcatcttcta
    42181 aaatgtcatg acataggaaa taatgttgct tagtatgaaa ttgataatag aaatttatca
    42241 gtgcctgttg cattttgtta tcaccccaat ttaaaagtaa gttattttca tgctataata
    42301 ttttagagaa ttatgcacat atgacgcaat acgaggtaga tattatgtat gaagttaaat
    42361 tagatgcttt caatggacca ttagatttat tgctgcatct tatccaaaaa tttgaaatag
    42421 atatttatga tattcctatg caagcattaa cagagcagta tatgcagtac gttcatgcaa
    42481 tgaaacagct tgaaattaat attgcaagtg aatacctagt attagcgtca gaactcttaa
    42541 tgattaaaag taagatgcta ttaccacaat caacatcaga tatggatgtt gatgatgacc
    42601 cacgggaaga tttagttggg cgtttaatag aatatcaaaa ttataaagaa tatactgcta
    42661 ttttaaatga catgaaagaa gaaagagatt tttattttac aaaaagaccg acagatttat
    42721 ctcatttgga aacagatgaa tcttgggatc caaatcatac gattgattta actgaattaa
    42781 ttgtagctta tcaaagagtt aaaaatagag ttgagttaaa tacacctaaa tctgttgaaa
    42841 tccgaaaaga gacatttacc attcaacaag ctacagaaca agtgacatcg agattgaaag
    42901 ataaagatca ttttaacttc tttagtctgt ttacgttttc tgagccaatt gaacaagtag
    42961 tcactcactt tttagctatt ttagagatgt caaaagcagg aataattaat attgagcaac
    43021 aacgtaattt tgaagatatt aacattatta gaggagtgaa ctaccatttt ggataatcat
    43081 ggtatattag agtcgctttt atttacagct ggcgatgaag gtttagatga aaaacaacta
    43141 ttagaaatat tagatatgtc gaaagaccaa ctcgttgaat taattgaaaa ttattcatca
    43201 catggattaa tgatacaacg atttggaacg acgtatgttt taacgactaa aaaagaagcg
    43261 gcaacgtata ttgaacaatt aattgaacaa aagtcacaaa tgaaattatc acaagcagca
    43321 atggaagtac tatcaattat tgcttataac cagccattat caagaagtga tattgaatta
    43381 attcgtagta tcaattcaga tggtgcagtt aagacattga ttgccaaagg actagttgag
    43441 gctaaagtgg ttaatgaaca gcgtagccaa cagttaatta ctactgattt atttttaaat
    43501 gtatttggta tttccaatat agaagatttg ccgacaactg aagaagacga tgaagaaatg
    43561 gatgcttttt tcagtaatct agtcaatcaa aaaggagaaa ataatgacta aagaattaga
    43621 acgattacaa aaacgtatag ctaatagcgg ttatacttca agacgtaagg cagaaacttt
    43681 aatttctgaa ggaaaagtga aagtgaatgg tacgactgtc actgaattag gaacaaaagt
    43741 gaagccatca gatacgattg aagttgaagg tattaaaata gaactagaag acaaaattta
    43801 cattttattc cataaaccaa ctcaagtgat aacaagtgta tctgatgata gaggacgtac
    43861 agtggttaca gattacttta aagatataga agcacgtatt tatcctgttg gtcgtttaga
    43921 ctatgatact tctggattgt tattacttac aaatgatggt gaatttacta atttaatgac
    43981 acatccaaga tatcaaatta agaagaaata tgtagcaaaa ttaaaaggtt acttaatgag
    44041 agaagaagtg aaagccctag aaaaaggtat tgaattagaa gatggtatga cgcaaccggc
    44101 tgaagtgaaa gttaagaaac aagataaaga taaaaacaca acattggttg aaattacaat
    44161 tacagaaggt cgtaatcgcc aagtcagaag aatgttcgaa cattttggtc atcaagtgac
    44221 gaaactgtct cgtattgaat atgggccttt aaatgttgtc ggtttgaatg ctggtgaagg
    44281 acgtgtattg acgcctcatg aagtaaaagt gatgcgtcat ttagcagaac atgggaaata
    44341 attaaataaa atatgtattt atcacaaagt ttgagaattt tttcacaaaa ttttaggttt
    44401 ttaataactg tatgcgcttt cctgtgatat aatacttttg taaagaaaag catgtgtggg
    44461 aggtatgacc tgtatgtcga acgaaatact tatcgtagat gatgaggata gaatcagaag
    44521 attacttaaa atgtatttag aaagagaatc ttttgaaatc catgaagcaa gtaatggcca
    44581 agaggcttat gaacttgcaa tggagaataa ttatgcttgc atactactag atttaatgtt
    44641 gcctgaaatg gatggtatcc aggtggcaac taaattgcgt gaacataaac aaacaccgat
    44701 tattatgttg actgctaaag gtgaagaaac aaaccgtgtt gaaggttttg aatctggtgc
    44761 agatgattat atcgtcaaac cattttcacc aagagaagta gtcttaagag ttaaagcact
    44821 tctaagaaga acgcaatcta caactgtaga acaaagcgaa cctcacgcac gtgatgtgat
    44881 tgaatttaaa catttagaaa tagataatga tgcacatcgc gtacttgctg ataatcaaga
    44941 agttaatttg actcctaaag agtacgaatt attaatatat ttagctaaaa caccaaataa
    45001 agtatttgac cgtgaacaat tattaaaaga agtttggcat tatgaattct atggtgattt
    45061 aagaacagtt gatactcatg ttaaacgact tagagaaaag ttaaatcgtg tgtctagcga
    45121 agctgcgcat atgattcaaa cagtctgggg cgttgggtat aaatttgagg ttaaatctaa
    45181 tgatgagccg gctaaatagt gtcgtaatta aactgtggtt aactattatt ttaatagtga
    45241 cgacagtttt aattttatta agtattgctt taattacctt tatgcaatac tatttcacac
    45301 aagaaaccga aaatgccata agagaagatg ctagacgtat aagttcactg gtcgaacaat
    45361 cacataataa agaagaagca ataaaatata gtcaaacatt aattgaaaat cctggtgggt
    45421 tgatgattat aaataataaa catcgtcaat caacggcttc actttctaat attaaaaagc
    45481 aaatgttgaa tgaagtagtc aacaacgacc attttgacga tgtgtttgat aaaggtaaat
    45541 ctgttactcg aaatgtaacg attaaagaaa agggttcatc tcaaacatat attttgttag
    45601 gctatccaac aaaagcacag aagaatagtc atagcaaata tagtggagtc tttatatata
    45661 aagacttgaa atcaatcgaa gatacaaata atgctattac gattatcact ataattacgg
    45721 ctgttatttt cttaacaatt acaacagtct ttgcgttttt cttatcgtca agaattacaa
    45781 aacctttaag acgtttaaga gaccaagcta cacgtgtatc tgaaggggat tactcttata
    45841 aaccttctgt cacaacgaaa gatgaaattg gtcaattatc gcaggcattt aatcagatga
    45901 gtacagaaat cgaagagcat gtcgacgcat tatccacatc taaaaatatt agagacagct
    45961 taattaactc tatggtagaa ggtgtcctag gtattaatga gagtcgacaa attatcttat
    46021 ctaataagat ggcgaatgat attatggaca atattgatga agatgctaaa gctttcttat
    46081 taagacaaat tgaagatact tttaaatcaa aacaaacgga aatgcgtgat ttagaaatga
    46141 atgcacgatt ctttgttgtg accacaagct atatcgataa gattgaacag ggaggtaaaa
    46201 gtggtgttgt tgtgacagtt cgtgatatga ctaatgagca caatctagat caaatgaaga
    46261 aagatttcat tgctaatgta tcacatgaat tacgaacacc tatatcatta ctacaaggtt
    46321 atactgaatc aattgtagat ggtattgtta cagaaccgga tgaaataaaa gaatcgctcg
    46381 ccgttgtcct tgatgaatcg aaacgtttaa atcgattagt taatgaattg ttaaatgtcg
    46441 cacgcatgga tgctgaaggg ttatccgtaa ataaagaagt tcagcctatt gcagcgttac
    46501 tagataagat gaaaattaag tatcgccaac aagctgatga tttaggtcta aatatgactt
    46561 ttaattattg taagaagcgt gtttggagtt atgatatgga tcgcatggac caagtactaa
    46621 cgaacttaat tgataatgca tcacgttata cgaaacctgg agatgaaatt gcaattactt
    46681 gtgatgaaaa tgaaagcgaa gatattttat acattaaaga tacaggcaca ggcattgcac
    46741 cagaacattt acaacaagta tttgatcgtt tttataaagt tgatgcagcg agaacgcgag
    46801 gtaaacaagg taccggttta ggtttgttca tttgtaaaat gattatcgaa gagcatggtg
    46861 gttccattga tgttaaaagc gaattaggaa aaggcacaac atttattatt aaactaccaa
    46921 aaccagaata aaactgaata tagttattta agaacgcatg ttattgatta gagactctaa
    46981 tttatagcat gcgttttttg attgatgtcg aaagttttgt aagtggatta ggattagggt
    47041 ttttgcgaat atcaactatt aaatatatta ctaatttata taaaaatata aagtttgata
    47101 aagttattta tttgattata aaaatagggt aaaatataga tatattgtaa taattaaatt
    47161 attcgaggtg tcatatgaaa aaattcattg gatcagtttt agctacgaca ttaattttag
    47221 ggggatgttc catgatggaa aatgaatcaa gtaaagacac gaatac
//
LOCUS       DAPDIM010000014        46395 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000014 DAPDIM010000000
VERSION     DAPDIM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 46395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46395
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.014"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..227
                     /gene="sarU"
                     /locus_tag="RFE25_000853"
     CDS             <1..227
                     /gene="sarU"
                     /locus_tag="RFE25_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarU"
                     /protein_id="HDU2815944.1"
                     /translation="EILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIV
                     LIKINKIQYNTIKSIFTDTSKILKPRKFFF"
     gene            complement(438..1304)
                     /gene="galU"
                     /locus_tag="RFE25_000854"
     CDS             complement(438..1304)
                     /gene="galU"
                     /locus_tag="RFE25_000854"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDU2815945.1"
                     /translation="MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEE
                     AARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYV
                     RQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQ
                     EVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLK
                     TQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMR
                     EELTRFIKALGL"
     gene            complement(1485..4601)
                     /gene="fnbA"
                     /locus_tag="RFE25_000855"
     CDS             complement(1485..4601)
                     /gene="fnbA"
                     /locus_tag="RFE25_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein FnbA"
                     /protein_id="HDU2815946.1"
                     /translation="MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTT
                     VEENGNSATDNKTSETQTTATNVNHIEETQSYNATVTEQPSNATQVTTEEAPKAVQAP
                     QTAQPANVETVKEEEKPQVKETTQPQDNSGNQRQVDLTPKKVTQNQGTETQVEVAQPR
                     TASESKPRVTRSADVAEAKEASDVSEVKGTDVTSKVTVESGSIEAPQGNKVEPHAGQR
                     VVLKYKLKFADGLKRGDYFDFTLSNNVNTYGVSTARKVPEIKNGSVVMATGEILGNGN
                     IRYTFTNEIEHKVEVTANLEINLFIDPKTVQSNGEQKITSKLNGEETEKTIPVVYNPG
                     VSNSYTNVNGSIETFNKESNKFTHIAYIKPMNGNQSNTVSVTGTLTEGSNLAGGQPTV
                     KVYEYLGKKDELPQSVYANTSDTNKFKDVTKEMNGKLSVQDNGSYSLNLDKLDKTYVI
                     HYTGEYLQGSDQVNFRTELYGYPERAYKSYYVYGGYRLTWDNGLVLYSNKADGNGKNG
                     QIIQDNDFEYKEDTAKGTMSGQYDAKQIIETEENQDNTPLDIDYHTAIDGEGGYVDGY
                     IETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHHADVVE
                     YEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDE
                     LPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEG
                     GQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNKGDQSFEEDTEKDKPKY
                     EHGGNIIDIDFDSVPQIHGFNKHNEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPKVSG
                     QNEGQQTIEEDTTPPTPPTPEVPSEPETPMPPTPEVPSEPETPTPPTPEVPSEPETPT
                     PPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQ
                     GKVVTPVIEINEKVKAVAPTKKAQSKKSELPETGGEESTNKGMLFGGLFSILGLALLR
                     RNKKNNKA"
     gene            complement(4585..4687)
                     /locus_tag="RFE25_000856"
                     /pseudo
     CDS             complement(4585..4687)
                     /locus_tag="RFE25_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501263.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5070..6428)
                     /locus_tag="RFE25_000857"
     CDS             complement(5070..6428)
                     /locus_tag="RFE25_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease"
                     /protein_id="HDU2815947.1"
                     /translation="MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALML
                     GIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHV
                     QWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLP
                     PHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISA
                     LGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTA
                     GTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGG
                     VGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVAL
                     VVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISL
                     FV"
     gene            complement(6545..8098)
                     /gene="gntK"
                     /locus_tag="RFE25_000858"
     CDS             complement(6545..8098)
                     /gene="gntK"
                     /locus_tag="RFE25_000858"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDU2815948.1"
                     /translation="MKYMIGVDIGTTSTKSVLYDENGAFIMKHQIGYDLHTPNVDVSE
                     ENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWAD
                     NRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKT
                     YIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMFPELVPTTYVMKGM
                     KERYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTD
                     YKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIA
                     KRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYT
                     VYLALIEVMNETPNMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGL
                     KAVGDIEDFSIVSSMVGATNNHTPFEENVAVYQELVSIFINLSRSLTENYEQIADFQR
                     QHMAENKTQ"
     gene            complement(8122..8802)
                     /locus_tag="RFE25_000859"
     CDS             complement(8122..8802)
                     /locus_tag="RFE25_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDU2815949.1"
                     /translation="MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMA
                     KQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRV
                     KNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHL
                     KPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGK
                     DIEGFWLN"
     gene            complement(8955..9719)
                     /locus_tag="RFE25_000860"
     CDS             complement(8955..9719)
                     /locus_tag="RFE25_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDU2815950.1"
                     /translation="MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTE
                     QQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLN
                     KIKNVQYYVNEASTSPITHLKDIEHVMSKSAEMKSIRRNIWISAGIIGIIQYSSIMSS
                     ILMKNKWPFLIALPFMNCYGIGVTFYYQQKVAYLCPNCQHIFSPSLWAVIKAKHTATT
                     RRFECPNCHETHYCIEVPKAHMSTEQLEISHIQHNN"
     gene            complement(9884..10576)
                     /locus_tag="RFE25_000861"
     CDS             complement(9884..10576)
                     /locus_tag="RFE25_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDU2815951.1"
                     /translation="MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHI
                     YSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAK
                     EHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSI
                     PVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVE
                     DKLQQIHSEITE"
     gene            complement(10807..11223)
                     /locus_tag="RFE25_000862"
     CDS             complement(10807..11223)
                     /locus_tag="RFE25_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDU2815952.1"
                     /translation="MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIA
                     AKKAKDWYRALSKEEIKALEEENFVQFHTATMEKAEVDSEYATTDNEEHIQEQSNQDK
                     SYFDSESIGNQSGGVRQREPLMDGAHPKVVESFKDV"
     gene            complement(11362..13185)
                     /locus_tag="RFE25_000863"
     CDS             complement(11362..13185)
                     /locus_tag="RFE25_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDU2815953.1"
                     /translation="MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVII
                     CNLAFAICMMLGTLTAKTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPI
                     NLPIAPEEALYRGFAILVGGILATMMVLITIVFSKNKAEEQAIQNDFKLISKLLHTYN
                     DKAAFLQVAKTAVDSFKASDKLLITSTSSNDKLSRRFQKLLLLHTSAQGIYSELLELN
                     AKQIRPLPDELIEMMDHIIAQLDNSDENVRYWRKEVTVTEEFQNLFNHILKIDEMVHA
                     NEARIAYEADMRKPLYSKRIYQNLTLDSIVFRNTLRYTAIMMIAIFIALMFDFEKAYW
                     IPLSAHTILLGTSTIHAIERGMARGLGTILGVLVLSVILLFSIPTPVAVILMGIAALF
                     TEALVGANYAIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAIGIVIAIIGLFVLG
                     QRTASVLLPNVMAEVVRKEATLFHYLFSENQYKDNVYQKNTAMNLSVKLNNMTQVYNA
                     ANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANEDRLTINEQLMGEYLATFENIAK
                     HLELNTELEIKILPDLPQYNYIQSAMMNIQHNGFRERDKNV"
     gene            complement(13662..14939)
                     /locus_tag="RFE25_000864"
     CDS             complement(13662..14939)
                     /locus_tag="RFE25_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002463344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2815954.1"
                     /translation="MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMT
                     KPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLI
                     YLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
                     AFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSP
                     PWNNFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMF
                     FLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLG
                     LGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTF
                     QLLIVPAVIAVIMWFYVKPDQPLIVSDDKAIEK"
     gene            15486..16097
                     /locus_tag="RFE25_000865"
     CDS             15486..16097
                     /locus_tag="RFE25_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDU2815955.1"
                     /translation="MEQIITEFISRFGYAAIFILILLENVLPIVPSEIILTFAGLMSV
                     KSHLSILTLFIIATIASFIGLLILYYICRLISEERLYRFIDRHGKWIKLKSKDLKRAN
                     DWFKKYGVWAVFICRFIPVLRVLITIPAGVNRMNVVTFTVISLIGTTIWNFGLILLGR
                     TLSDSFGMLMTGLHTYSRIMYVVIIIAVIYFAIRYIGKRKRVK"
     gene            complement(16106..16205)
                     /locus_tag="RFE25_000866"
                     /pseudo
     CDS             complement(16106..16205)
                     /locus_tag="RFE25_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501275.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16615..17310
                     /locus_tag="RFE25_000867"
     CDS             16615..17310
                     /locus_tag="RFE25_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDU2815956.1"
                     /translation="MGVLTIEHLTKKIGNKTILEDVSFKLKRGQIVGLVGANGAGKTT
                     LMKVILGYSSFQSGNFNVINSKDSKSNIGALIENPGIYPFMSGYENLKLLNESKNTQD
                     IDKIVSQLHMDEYIHKKAKTYSLGMKQKLGIAIAFLNEPQFIILDEPMNGLDPKAVRD
                     VRELIVQKSQEGVTFLISSHILSELVKITNSILIINKGKIVTETSEEELKQFKDNDLE
                     NVLLEIIEREDQA"
     gene            17312..18082
                     /locus_tag="RFE25_000868"
     CDS             17312..18082
                     /locus_tag="RFE25_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815957.1"
                     /translation="MGTLIKQECFKLFKKKSTFIAPIVFILLMVAQGYIATKYNEIFT
                     PQESFTSAYNGFSWFAFLLIIQASTIISMEFHYGTIKNLLYREYSRTTMIVSKIITLF
                     IISLIYFVITIIASIVIGSLFFNDLNIFESSGNQLSLLNQLLLVSLGTFVGVWLVLSL
                     TLLLSSATNSTGVAIAVGIVFYFASSILAVIQTALLEKIDWLKWNPINMMNIMLQTVE
                     KGFSKSTKLELHELFIGNIAYISIFLILVVFIFKKKNI"
     gene            18455..20419
                     /locus_tag="RFE25_000869"
     CDS             18455..20419
                     /locus_tag="RFE25_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HDU2815958.1"
                     /translation="MTQITEKELKKKYLDLLSQNFDTPEKLATEIINLESILELPKGT
                     EHFVSDLHGEYEAFQHVLRNGSGNVRAKINDIFKERLSTKELNDLTALVYYPEDKLKL
                     IKSDFQSCGQLNVWYITTIEHLIELIKYCSSKYTRSKLRKALPKQYVYIIEELLYKSN
                     EYQNKKSYYETLVNQVIELKQADDLIIGLAYSVQRLVVDHLHVVGDIYDRGPQPDKIM
                     DTLINYHSLDIQWGNHDVLWVGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPL
                     LTLAEKYYDADNPAFKPKKRPDKHERLTQREESQITKIHQAIAMIQFKLEIPIIKRRP
                     NFEMEERLVLEKVNYDTNEITVYGNTYPLKDTCFQTINRNNPAELLPEEEEVMNKLLL
                     SFQQSEKLRRHMSFLMRKGSLYLPYNGNLLIHGCIPVDENGEMESFEIDGHTYSGQEL
                     LDVFEYHVRKSFDEKENTDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIADKASHK
                     EEKNPYYHLREDVNMVRKMLSDFGLNPDEGRIINGHTPVKEINGEDPIKADGKMLVID
                     GGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQQFNAKEKILSEGIDELSIKRVVDKELQ
                     RKKIRDTNIGKELQAQIDILKMLMHDRYLD"
     gene            20761..21840
                     /locus_tag="RFE25_000870"
     CDS             20761..21840
                     /locus_tag="RFE25_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815959.1"
                     /translation="MRILKESIIVAFAFVGVVVGAGFATGQEIFQFFTSHGAYSISGI
                     IVTGLLITLGGMVVMHTGHHLKSRNHSDSINYFLYPSIARGFDIILTMFMLSLAIIMT
                     AGGASTIHQSFNLPYWLSALILVAFILATLFLKFDRLIAVLGGVTPFLIAIVIMIAVY
                     YFTTSHLDFTAANNDAQIHKQKSLSPGWWFDAINYASLQIAAAFSFLSVMGSKVKYRD
                     STLYGGLIGGLIITFLLMMINLGLISQFDKIKHVDLPTLKLATQMSPSIGIIMSVIMI
                     LVIYNTVVGLMYAFASRFSVPFSRRYFIIIITMAVITYISTFIGFISLIGKVFPIMGL
                     FGFILLIPVLYKGLIKRITGKSHID"
     gene            complement(21945..22538)
                     /locus_tag="RFE25_000871"
     CDS             complement(21945..22538)
                     /locus_tag="RFE25_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2815960.1"
                     /translation="MEHIFREGQKGAPTLILLHGTGGDEFDLLPLGEALNENYHLLSI
                     RGQVSENGMNRYFKRLGEGVYDEEDLEFRGQELLAFIKEAAERYEFDIEKAVLVGFSN
                     GSNIAINLMLRSEAPFKKALLYAPLYPVEVTSTKDLSDVSVLLSMGKHDPIVPLAASE
                     QVINLFKTRGAVVEEVWVNGHEITETGLTAGQQILGK"
     gene            complement(22569..23528)
                     /locus_tag="RFE25_000872"
     CDS             complement(22569..23528)
                     /locus_tag="RFE25_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001628197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HDU2815961.1"
                     /translation="MINNHELLGIHHVTAMTDDAERNYKFFTEVLGMRLVKKTVNQDD
                     IYTYHTFFADDVGSAGTDMTFFDFPNITKGQAGTNSITRPSFRVPNDDALMYYEQRFD
                     EFGVKHEGIQELFGKKVLPFEEVDGQVYQLISDELNDGVAPGVPWKNGPVPVDKAIYG
                     LGPIEIKVSYFDDFKNILETVYGMTTIAHEDNVALLEVGEGGNGGQVILIKDDKGPAA
                     RQGYGEVHHVSFRVKDHDAIEAWATKYKEVGINNSGIVNRFYFEALYARVGHILIEIS
                     TDGPGFMEDEPYETLGEGLSLPPFLENKREYIESEIRPFNTKR"
     gene            complement(23606..24040)
                     /locus_tag="RFE25_000873"
     CDS             complement(23606..24040)
                     /locus_tag="RFE25_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDU2815962.1"
                     /translation="MDRTKQSLNVFVGMNRALDTLEQITKEDVKRYGLNITEFAVLEL
                     LYNKGPQPIQRIRDRVLIASSSISYVVSQLEDKGWITREKDKDDKRVYMACLTEKGQS
                     QMADIFPKHAETLTKAFDVLTKDELTILQQAFKKLSAQSTEV"
     gene            24266..24550
                     /locus_tag="RFE25_000874"
     CDS             24266..24550
                     /locus_tag="RFE25_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDU2815963.1"
                     /translation="MSNLEIKQGENKFYIGDDENNALAEITYRFVDNNEINIDHTGVS
                     DELGGQGVGKKLVKAVVEHARENHLKIIASCSFAKHMLEKEDSYQDVYLG"
     gene            24721..25527
                     /locus_tag="RFE25_000875"
     CDS             24721..25527
                     /locus_tag="RFE25_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDU2815964.1"
                     /translation="MAFHDKTATQVTNIELNVRDLDLMTTFYKNILGLSVKSSDDNTT
                     VLSVGTGGHTLTLHLLEDGRQTSPREAGLFHIAFLLPTTEDLANFLYFVAQKNMGIGA
                     GDHLVSEALYFNDPEGNGIEVYRDRPSSSWEWQNGKVKMDTLEVDSQTLLTHRTDEGW
                     QGMPAKGMIGHLHLKTHDLDAAYQCYIEQLGFQHVSDFPRALFMSTNHYHHHIAANTW
                     QSNQARQNNAQSYGLTHVDIYQPDASTHTFTAPEGFDITVHSNTDLVPEK"
     gene            complement(25648..26319)
                     /locus_tag="RFE25_000876"
     CDS             complement(25648..26319)
                     /locus_tag="RFE25_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDU2815965.1"
                     /translation="MSNMNQTIMDAFHFRHATKQFDPQKKVSKEDFETILESGRLSPS
                     SLGLEPWKFVVIQDQALRDELKAHSWGAAKQLDTASHFVLIFARKNVTSRSPYVQHML
                     RDIKKYEAQTIPAVEQKFDAFQADFHISDNDQALYDWSSKQTYIALGNMMTTAALLGI
                     DSCPMEGFSLDTVTDILANKGILDTEQFGLSVMVAFGYRQQDPPKNKTRQAYEDVIEW
                     VGPKE"
     gene            26589..27581
                     /locus_tag="RFE25_000877"
     CDS             26589..27581
                     /locus_tag="RFE25_000877"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDU2815966.1"
                     /translation="MTKIMFFGTRDYEKEMALNWGKKNNVEVTTSKELLSSATVDQLK
                     DYDGVTTMQFGKLENDVYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYS
                     PETIAEYSVSIALQLVRRFPDIERRVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAA
                     TAKIYAGFGATITAYDAYPNKDLDFLTYKDSVKEAIKDADIISLHVPANKESYHLFDK
                     AMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFTNDWTNKD
                     IDDKTLLELIEHERILVTPHIAFFSDEAVQNLVEGGLNAALSVINTGTCETRLN"
     gene            complement(27828..28628)
                     /locus_tag="RFE25_000878"
     CDS             complement(27828..28628)
                     /locus_tag="RFE25_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDU2815967.1"
                     /translation="MVKAIAVDMDGTFLDSKKTYDKPRFEAIFTELRNRDITFIAASG
                     NQYAKLKSIFGDRDMYFISENGAVIYKGNELYNYKSFNRQVFQQVVDYLNMNQSIDQL
                     VICGLKSAYILKHTTEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
                     DEEVATQFSNDIKLVSSGHDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANND
                     KDMLAFAKHSYVMENSHDEELFNIASAVAPSNDKQGVLTIIEQEVLNK"
     gene            28948..29583
                     /locus_tag="RFE25_000879"
     CDS             28948..29583
                     /locus_tag="RFE25_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDU2815968.1"
                     /translation="MKLNNYSLKVKNKQLVDNCDLNFYLGQINHIVGKNGVGKSLLAK
                     DFLLNNSGNIPKSISQNVTLISSSSNIPNDITKDFLLSLLKSKFENNRQTFDKIYNIL
                     NIEAIPSNVLLKNLSDGQKQKLKLLSFLLEDHDLIILDEVTNALDKKTVNEIYEFLND
                     FIQSHQTKTIINITHNLSDLSALPGKYFIFKDLQIEEYQSKEEVINDYINL"
     gene            29589..30320
                     /locus_tag="RFE25_000880"
     CDS             29589..30320
                     /locus_tag="RFE25_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease"
                     /protein_id="HDU2815969.1"
                     /translation="MSTLKLEFKKSISNKIIYTLGVLFIFLFLLGYFLPIGIDKVKNL
                     SYGQFFFSSYTVATEFGFLLFSFVIAYFINKEYSNKNILFYKLIGDNIFTFFYKKVAV
                     LFIECLIYIILGITIISIIYSDFSHYLLLIILFSLVILQYILVVGTISMVSPNILISL
                     GISIVYWIGSVILVAINKNIFGIVAPFEASNTMYRAVEKILNNESTFICPTEIINTVS
                     FFVLLFIVNTIVLLLSRKRWLKIGM"
     gene            complement(30482..31102)
                     /gene="srtA"
                     /locus_tag="RFE25_000881"
     CDS             complement(30482..31102)
                     /gene="srtA"
                     /locus_tag="RFE25_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase SrtA"
                     /protein_id="HDU2815970.1"
                     /translation="MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQ
                     YDKNVKEQASKDNKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVS
                     FAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRD
                     VKPTDVEVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK"
     gene            31296..31787
                     /locus_tag="RFE25_000882"
     CDS             31296..31787
                     /locus_tag="RFE25_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDU2815971.1"
                     /translation="MIRCAKKEDLNAILAIYNDAIINTTAVYTYKPQTIDERIAWFET
                     KQRNHEPIFVFEENGSVLGFATFGSFRPWPAYQYTIEHSIYVDASARGKGIASQLLQR
                     LIVEAKAKGYRTLVAGIDASNEASIKLHQKFNFKHAGTLTNVGYKFDYWLDLAFYELD
                     LKD"
     gene            complement(31931..32101)
                     /locus_tag="RFE25_000883"
     CDS             complement(31931..32101)
                     /locus_tag="RFE25_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815972.1"
                     /translation="MLRLSIIFIAFIINTTITYGYTTEGTWVNLLFKSLSLSMIIVFM
                     FYYIRFVIEKKR"
     gene            complement(32158..32256)
                     /locus_tag="RFE25_000884"
     CDS             complement(32158..32256)
                     /locus_tag="RFE25_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815973.1"
                     /translation="MIKKKHLSGSLVPDRCFLIIFHKVEKIMGNTC"
     gene            complement(32275..33174)
                     /gene="sdaAA"
                     /locus_tag="RFE25_000885"
     CDS             complement(32275..33174)
                     /gene="sdaAA"
                     /locus_tag="RFE25_000885"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HDU2815974.1"
                     /translation="MFDSIRETIDYAVENNMSFADIMVKEEMELSGKSRDEVRAQMKQ
                     NLDVMRDAVIKGTTGDGVESVTGYTGHDAAKLRDYNETHHALSGYEMIDAVKGAIATN
                     EVNAAMGIICATPTAGSSGTIPGALFKLEKTHDLTEEQMIDFLFTSALFGRVVANNAS
                     VAGATGGCQAEVGSASAMAAAAAVAIFGGSPEASGHAMALAISNLLGLVCDPVAGLVE
                     IPCVMRNAIGSGNALISADLALAGIESRIPVDEVIEAMDKVGRNLPASLRETGLGGLA
                     GTPTGEAIKRKIFGTAEDMVKNN"
     gene            complement(33188..33868)
                     /gene="sdaAB"
                     /locus_tag="RFE25_000886"
     CDS             complement(33188..33868)
                     /gene="sdaAB"
                     /locus_tag="RFE25_000886"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HDU2815975.1"
                     /translation="MAKSYDYQSAFDIIGPVMMGPSSSHTAGAVKIGNSARAILGDIP
                     KNIEIHYYESFAQTHQGHGTDVAIVGGAMGYSTFDNRIKSSLEIAADDGIKIDIIEEE
                     GDSIGQHPNCAYIKSSRNDGRYIEIIGISIGGGTIKIKGIHINGLEVDLNHGLPILVV
                     DGNMTKAQVNHFINDINDMKLDCKDEFIKIDEDKCLVVIPLNKAISESTLNTIKEKYS
                     DVNVSYIN"
     gene            complement(33871..34914)
                     /locus_tag="RFE25_000887"
     CDS             complement(33871..34914)
                     /locus_tag="RFE25_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDU2815976.1"
                     /translation="MDILLGVGTLVLVLVIMTLFLKYAPYGKQGLQALSGAACATFLP
                     QAFLSYAIGGVFDIKFLQDIGDLAGSLSGIAVGILTCLNLGVAPVFAVIVGLVLHDFK
                     LLPAFIAAYCVAFLIKWIEKKVPEGLDLIVVILFAPAIAFGLASIITPGVLATLKQIG
                     SAVTAVGDNNPYALAVILGLVIPVTGMTPLSSMVLTSLLGLTGVPMAIGALTCTGSSF
                     VNLILFRKLNIGGPSKAFAVCIEPLTQIDLIAQYPVQLYGTNALIGVVNACIVTFSGL
                     VIGVKGMATPIAGAIVLFGFNNAVTSIVTIATVIIVSIVLAYIIGTLINKFNLMNINF
                     KMPSKKNHIKESV"
     gene            35464..35667
                     /locus_tag="RFE25_000888"
     CDS             35464..35667
                     /locus_tag="RFE25_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815977.1"
                     /translation="MQLSHSVKVAISIYLALIFITFTSYLVIILYTSMTGHDVSHFVL
                     DSQHSHHGSLTQKHLSLPEISFK"
     gene            35850..36785
                     /locus_tag="RFE25_000889"
     CDS             35850..36785
                     /locus_tag="RFE25_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDU2815978.1"
                     /translation="MRYLANNHSALRLKGIILAIVGACLWGLGGTVSDFLFKYKNINV
                     DWYVTARLVVSGVFLLIMYKMMQPKRSIFSVFQDRRMLGKLLIFSILGMLVVQYAYMA
                     SINTGNAAIATLLQYIAPVYIIIWFVIRGVAKLTLFDVLAIIMTLLGTFLLLTNGSFS
                     NLVVNPASLFWGILAGVALAFYTIYPSDLLNRFGSILIVGWAMLISGVAMNLRHPIWH
                     IDITKWDISIILFLIFGIIGGTALAFYFFIDSLQYISAKETTLFGTVEPVVAVIASSL
                     WLHVAFKPFQIVGIILIMILILLLSLKRQPEALDE"
     gene            complement(36866..37834)
                     /locus_tag="RFE25_000890"
     CDS             complement(36866..37834)
                     /locus_tag="RFE25_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2815979.1"
                     /translation="MRKKWSTLAFGFLVAAYAHIRIKEKRSVKSYMLEQGIRLSRAKR
                     RFMYKEEAMKALEKMAPQTAGEYEGTNYQFKMPVTVDKHYGSTVYNVNDKQDKHQRVV
                     LYAHGGAWFQDPLKIHFEFIDELAETLNAKVIMPVYPKIPHQDYQATYVLFEKLYHDL
                     LNQVADSKQIVVMGDSAGGQIALSFAQLLKEKHIVQPGHIVLISPVLDATMQHPEIPD
                     YLKKDPMVGVDGSVFLAEQWAGDTPLDNYKVSPINGDLDGLGRITLTVGTKEVLYPDA
                     LNLSQLLSAKGIEHDFIPGYYQFHIYPVFPIPERRRFLYQVKNIIN"
     gene            complement(37955..38311)
                     /locus_tag="RFE25_000891"
     CDS             complement(37955..38311)
                     /locus_tag="RFE25_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDU2815980.1"
                     /translation="MVKQLNSVEAFREFIHQYPLAVVHVMRDQCSVCHAVLPQIEDLM
                     QSYPNVPLAVINQSQVEAIAGELNIFTVPVDLIFMNGKEMHRQGRFIDMQRFEHHLKQ
                     MNDSVNNDVDEHEYRK"
     gene            complement(38353..38763)
                     /locus_tag="RFE25_000892"
     CDS             complement(38353..38763)
                     /locus_tag="RFE25_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDU2815981.1"
                     /translation="MTTEGLLVAEKEIEVNGYDIDAMGVVSNIVYIRWFEDLRTAFIN
                     QHMNYSTMINQGISPILMKTEAEYKVPVTIHDKPVGRIYLVKASKMKWVFQFEIVSAH
                     CVHCIGTQTGGFYRLSDKKITSVPQVFQDILATK"
     gene            complement(39143..41209)
                     /locus_tag="RFE25_000893"
     CDS             complement(39143..41209)
                     /locus_tag="RFE25_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIABC"
                     /protein_id="HDU2815982.1"
                     /translation="MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEI
                     APWLKNDIIVMISSVMEAAGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMN
                     ATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAW
                     CYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVLLSFAWPPIQDGLNSLSNFLLN
                     KNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLKD
                     GVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLMLSAGLTAFLTGITE
                     PLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSH
                     ALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGG
                     KENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHD
                     MAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPDQVFAGK
                     MMGDGIGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESESGVEVLIHIGIDTVKLNGEG
                     FESLINVDEKVTQGQPLMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGK
                     LIMTVK"
     gene            complement(41510..43249)
                     /locus_tag="RFE25_000894"
     CDS             complement(41510..43249)
                     /locus_tag="RFE25_000894"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HDU2815983.1"
                     /translation="MAKIKANEALVKALQAWDIDHLYGIPGDSIDAVVDSLRTVRDQF
                     KFYHVRHEEVASLAAAGYTKLTGKIGVALSIGGPGLIHLLNGMYDAKMDNVPQLILSG
                     QTNSTALGTKAFQETNLQKLCEDVAVYNHQIEKGDNVFEIVNEAIRTAYEQKGVAVVI
                     CPNDLLTEKIKDTTNKPVDTSRPTVVSPKYKDIKKAVKLINKSKKPVMLIGVGAKHAK
                     DELREFIEMAKIPVIHSLPAKTILPDDHPYSIGNLGKIGTKTSYQTMQEADLLIMVGT
                     NYPYVDYLPKKNIKAIQIDTNPKNIGHRFNINVGIVGDSKIALHQLTENIKHVAERPF
                     LNKTLERKAVWDKWMEQDKNNNSKPLRPERLMASINKFIKDDAVISADVGTATVWSTR
                     YLNLGVNNKFIISSWLGTMGCGLPGAMASKIAYPNRQAIAIAGDGAFQMVMQDFATAV
                     QYDLPLTVFVLNNKQLAFIKYEQQAAGELEYAVDFSDMDHAKFAEAAGGKGYTIKSAS
                     EVDAIVEEALAQDVPTIVDVYVDPNAAPLPGKIVNEEALGYGKWAFRSITEDKYLDLD
                     QIPPISVAAKRFL"
     gene            complement(43300..43989)
                     /locus_tag="RFE25_000895"
     CDS             complement(43300..43989)
                     /locus_tag="RFE25_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDU2815984.1"
                     /translation="MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGII
                     FVLLIFGISYNGYMKGGSWINHILNATVVCLAYPLYKNREKIKDNVSIIFASVLTGVM
                     LNFMLVFLTLKAFGYSKDVIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIG
                     SILGSMLLRFGRFESSIAKGLTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISS
                     VLIPVLILLFY"
     gene            complement(43982..44377)
                     /gene="cidA"
                     /locus_tag="RFE25_000896"
     CDS             complement(43982..44377)
                     /gene="cidA"
                     /locus_tag="RFE25_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like murein hydrolase modulator CidA"
                     /protein_id="HDU2815985.1"
                     /translation="MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFL
                     FYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIG
                     TCIVALSSGYIAEKMSVKHKHRKGVDAYE"
     gene            complement(44590..45468)
                     /locus_tag="RFE25_000897"
     CDS             complement(44590..45468)
                     /locus_tag="RFE25_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDU2815986.1"
                     /translation="MDIKHMKYFIEVVKQGGMTNASKSLYIAQPTISKAIKDIENEMG
                     TPLFDRSKRHLILTDAGQIFYEKSKEIVALYDYLPSEMERLNGLETGHINMGMSAVMN
                     MKILINILGAFHQQYPNVTYNLIENGGKTIEQQIINDEVDIGVTTLPVDHHIFDYTTL
                     DKEDLRLIVSREHRLAKYETVKLEDLAGEDFILFNKDFYLNDKIIENAKNVGFVPNTV
                     AQISQWHVIEDLVTNELGISILPTSISEQLNGDVKLLRIEDAHVHWELGVVWKKDKQL
                     SHATTKWIEFLKDRLG"
     gene            45635..45853
                     /locus_tag="RFE25_000898"
     CDS             45635..45853
                     /locus_tag="RFE25_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterile alpha motif-like domain-containing
                     protein"
                     /protein_id="HDU2815987.1"
                     /translation="MSFYEFMQSFLGDDTPLGELVDWINQDSNFPREVKSHSEILSYF
                     RTNPCPESISVPVIKRALSVFNQFTNVQ"
     gene            46243..>46395
                     /locus_tag="RFE25_000899"
     CDS             46243..>46395
                     /locus_tag="RFE25_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2815988.1"
                     /translation="MEYKKILIRLLIAFAVLFSADFTYQSVEQTHQSHAAVNYYSKNQ
                     CTWWAFK"
BASE COUNT        14448 a         8641 c         6950 g        16356 t
ORIGIN      
        1 atgagatact aaatttaaaa gatttgtttg aaagtattag atttatgtat cctcaaattg
       61 ttaggtcagt taatagatta aataataaag gtatgctaat caaagaacga tcccttgcag
      121 atgaaaggat tgtgttaatc aaaataaata aaatacaata taacactatt aaaagcatat
      181 tcacagatac ttccaagatt ctcaaaccaa gaaaattttt cttttaaatt taaacagatt
      241 tacctcttga taaaataaat aagcaatcat aatacttctc aatttagtat aaataaaaat
      301 acataattaa ctttcttttg tttttatatt atttcaatac cctactatat atcacaacac
      361 ataaattaag catgacactc attcaattta gttcaccatt tcgtgttcca attttattga
      421 gtatcatgct tttaatatta taaacctaat gctttaataa atcgtgttaa ttcttctcgc
      481 atactgtcat ctttcaacgc atattctatt gttgttttga caaatcctaa tttttctcca
      541 acgtcataac gttcgccttc gaagtcatat gcatacactt gattatcatt gttcatacgc
      601 tcaatcgcat ctgttaactg aatttcgtta cctgcgcctt ctttttgcgt ttttaaataa
      661 tcgaaaattt caggcgttaa tacatatcgg cccataatag ctaggtttga tggtgccgta
      721 ccttgtgctg gcttttcaac aaactttttc acttcatact gacgtccatt tttagttaat
      781 ggatcaataa ttccataacg atgagtatct gcttccggaa cttcttggac acctataact
      841 gagtgccccg tttcttcata aacgtcaatc aactgtttca ctgctggcac ttcagattca
      901 acaatatcgt cacctaataa taccgcaaat ggttcattgc cgataaattg acgcgcagaa
      961 ctaatcgcat gccctaaacc tttttgttct ttctgtctta cataaaaaat attcgcaagt
     1021 tctgtcgagt attgaacttt ttctagtaat tcagatttac ctttttcttt taacaccatt
     1081 tctaattctt tttgactatc aaaatgatct tcaatcgcgc gtttgtggcg acctgtcact
     1141 ataataatat cttcaattcc agctcttgca gcttcttcaa cgatatattg tattgtgggt
     1201 ttatctaaga taggaagcat ttcctttggc atcgctttag ttgctggtaa aaatctagtc
     1261 cctaaaccag cagcgggaat gattgccttt tttatttttt tcaaagttaa tgtgctcctt
     1321 ttcctaagta ttaaatctat gtatcaacgt cattttaaca ctaattagaa cgccttcata
     1381 gtgtcattga gtatgtaatt atttcttggg aaatttgatt taattttaaa aaaacaggtt
     1441 tacttcatat aatttatgaa ataaacccgt caatttttgt ttaattatgc tttgttattc
     1501 tttttatttc tgcgtaataa tgctaaacct agaatgctga ataatccgcc gaacaacata
     1561 cctttgtttg ttgattcttc tccacctgtt tcaggtagtt cagatttctt agattgtgct
     1621 tttttagttg gtgccactgc tttaaccttt tcattgattt caataacagg tgttactact
     1681 ttaccttgtt ccactggttt agaaggcttt ttaggttctt cttttgcggg tggtactggt
     1741 ttaccaggtt cagctggtac ctctggtgtt ggcggtgttg gtgtttctgg ctcactcggc
     1801 acttctggtg tcggtggtgt tggtgtttcc ggctcacttg gtacttccgg agtcggtggt
     1861 gttggtgttt ccggctcact tggtacctct ggtgttggtg gcgttggtgt ttccggctca
     1921 ctcggtactt ctggtgtcgg tggcattggt gtttccggct cactcggtac ttctggtgtc
     1981 ggtggcgttg gcggcgttgt atcttcttca atcgtttgtt gaccttcatt ttggccgctt
     2041 acttttggaa gtgtatcttc ttcaaagtca acactattgt gtccaccgaa ttgataatta
     2101 ggtttatctt tgtttgtatc ttcttcaata atttcattat gcttattgaa tccatgaatt
     2161 tgtggcacac tgtcgaagtc gatatcaatg atattaccgc catgttcata tttaggcttg
     2221 tctttctctg tatcttcttc gaatgactgg tcacctttat tttgaccatg aatttgaggt
     2281 acactgtcga aatcgatatc tacgatattg ccaccttgtt catatttagg tttgtcttct
     2341 tctgtgtctt cctcgaatga ctggttaccg ctattttggc caccttcgta acctaattca
     2401 ctcttaatat caacgtggct attttcttcg atttcttcaa tcacgccata attaccgtga
     2461 ccattttcag ttcctaaacc agaatgagaa atatgatgat tgttttcagt aatttcctcg
     2521 attggtcctt gtgcttgacc atgttcttca ggtagttcat ctactagttc aatcagatta
     2581 ctttcagtcg tatattcttt cgtatcttca attgttgtat ggtcgctcac tgcgccagtt
     2641 acaatacctt ttgtagactc ttcgtcaaat tcaactaagt tagactcagt tgttacttgg
     2701 ccaccacctg gatttgtatc ctcttcatat tcaacaacat cagcgtgatg ttttgaattt
     2761 tcatgtgtcg attcttcaaa gtcaattgga tttgattcct cagaggactc agtgtatcct
     2821 ccaacgtgac ccgcttcact atccacagca gtatggtaat cgatatcaat agctgatgaa
     2881 tccgtttctt ctattgtttc aatataccca tcaacataac caccctcacc atctatagct
     2941 gtgtggtaat caatgtcaag cggtgtattg tcttgatttt cttctgtttc aataatttgc
     3001 ttggcatcgt actgcccgct catagttcct tttgcagtat cttctttata ttcaaaatca
     3061 ttatcttgaa taatttgtcc atttttacca ttgccgtcag ctttattgct atataaaact
     3121 aaaccattat cccaagttaa acgatatccc ccataaacat agtaagattt atatgctcgt
     3181 tctggatacc catataattc agttctaaaa ttaacctgat ctgacccttg caaatattca
     3241 cctgtataat gaatgacata cgttttatcc aacttatcta aattcaatga gtaactacca
     3301 ttgtcttgca cactcaattt tccattcatt tcctttgtta catctttgaa tttgttagta
     3361 tctgatgtat ttgcataaac actttgtggc aattcatctt ttttccctag atattcatat
     3421 actttaacag taggttgtcc accagctaaa ttactacctt cagtcaacgt ccctgttact
     3481 gatacagtgt ttgactggtt tccattcatt ggcttaatat aagctatatg tgtaaattta
     3541 ttagattctt tattaaatgt ttcaattgat ccatttacat ttgtataact attgctaaca
     3601 cctggattat aaacaactgg tattgttttt tctgtttctt caccatttaa tttagaagta
     3661 atcttttgtt ctccattgct ttgtacagtt ttagggtcaa taaataagtt gatttctaaa
     3721 ttagctgtta cctctacctt gtgttcaatt tcgttagtaa atgtatatct tatgttacca
     3781 ttccctaaga tctcacctgt agccattaca actgagccat ttttaatctc tggtaccttt
     3841 ctagctgttg aaaccccata agtatttaca ttatttgata atgtaaaatc aaaataatct
     3901 cctcttttta atccatctgc gaatttcaat ttgtatttca atacgacacg ttgaccagca
     3961 tgtggctcta ctttatttcc ttgaggtgcc tcaatagaac cactttctac tgtaacttta
     4021 cttgtaacat ctgtgccttt aacttctgaa acgtcactag cttccttagc ttccgctaca
     4081 tctgctgatc ttgtcacacg tggcttactt tctgatgccg ttcttggctg tgccacttca
     4141 acttgtgttt ctgtcccttg attttgtgta acctttttag gtgttaaatc tacttgtctt
     4201 tgatttccgc tattgtcttg aggttgtgtc gtttccttaa cttgaggttt ctcttcttct
     4261 ttaactgttt ctacatttgc tggttgtgca gtttgtggtg cttgtactgc ttttggtgct
     4321 tcttcagttg ttacttgtgt tgcgtttgac ggttgttctg ttactgttgc gttatatgat
     4381 tgagtttctt ctatatgatt aacgttagta gcagttgttt gtgtttcact tgttttatta
     4441 tcagtagctg aattcccatt ttcttctact gtagttgtct tttgttctga tgctgcagct
     4501 tctttatctt gtcccatccc aacaacgatc attgttccta agaatactga tgctgctccc
     4561 aatttatgtt ttctaatgcc gtacctaaga ttgtttttca ctataatatc tccctttaaa
     4621 tgcaaaattc attaattttt ttaaacttaa taaatgcaag tctatattgt tcggttttta
     4681 aaagcaatac aaaaaagcga gttaatgaaa agttaagatt gtcattaatt ttatgttaat
     4741 tgataatttt attatttgaa atatacctat aaattgtatt caagtcatca taaacccttg
     4801 tcacacaagg cttgtatttt ttatacttat ttttcaaatt aaattcatca ttatctaatt
     4861 taaaacaata tactaagtgt ttcataatta tcgcctgtac aatacgcaca aaaacatgtc
     4921 ttgaaacgcc tttcattaca ctaaaatccc caatatactt tttatatcgt tcggattctg
     4981 actatttcag acgattttct gcataaaaat aaacgtgttt caaggcaata tattgcaatt
     5041 acctaaaaac acgtttactt aatatttagt taaacaaata agctgatgaa tagaatgaag
     5101 atgatacctg aaacggaaat aatcgtttct aataatgacc atgttaagaa tgtttctttt
     5161 acagttaaac caaaatattc tttaaacatc caaaatcctg cgtcatttac atgagacaaa
     5221 atcacactac ctgcacctat cgcaagtaca actaatgcaa catttacatc tgatgattgt
     5281 aataatggta agacaatacc tgtagttgaa atcgcagcta ctgtagccga acctaatgcg
     5341 atacgtagca cagctgcaac aatccatgct agtaaaattg gagacatctc tgtaccttca
     5401 aacattttag caattgtatt tccgacacca ccgtcaatta atacttgttt aaatgtaccg
     5461 ccaccgccaa taatcaataa catcattccg attggataaa tcgcattcgt cactgattcc
     5521 ataatatgat tcatcttacg ttttctcatt aatcccatcg taacgattgc aaataatact
     5581 gctattagca tggctgtccc tgctgttcct atcatataaa tgatagattc aaatagattt
     5641 gtaggtttgt cgtgcccagt tacaagttgc gttatcgtag acactaacat taatatgact
     5701 ggtaatgttg cagttaataa actcatacca aatcctggca tctcttgatc cgtaaattct
     5761 ttttgtgcac ctaacgctga aatatcgcct tctcgtgtat acgcagacgg aatcattttt
     5821 tgtgcaactt tgttaaatat aggtcctgca atgagtgtaa ctggaatggc aataatcata
     5881 ccgtacagta atacatctcc aacatttgcc tttaattctt ttgcgatgac taccggtcct
     5941 ggatgtggtg gtaaaaagcc atgtgtcaca gataaagctg ttaccatagg tagtcctagt
     6001 tttaacactg aaacatttgc gcgttttgct actgtaaata ctaatggaat cagtaagact
     6061 aaacctactt caaagaacaa tgcaataccg acgataaatg ctgcaacaag cattgcccat
     6121 tgtacatgtt tttgaccaaa tttttgaatc aacgtgtctg caattcgagt tgcaccacca
     6181 ccatcagcaa gtaatttccc aagtatggca cctaaaccga atattagtgc aatgtggccg
     6241 agcgtactgc ccatcccttt ctcaatcgtc tccataattt tagtcaatgg tatacctagc
     6301 attaacgctg taatcatcga tgtgataatt aatgaaataa atgtatttaa tttaaaccca
     6361 ataattaata ctaataaaat aacgatacct aaaacaacac tgattaacgg ccatatttcg
     6421 ttaaacatga cattcccctc tttctctttt caatagaatg taacaccgtc gtcgcgcacg
     6481 tattccagat aatatatagt agtcatggca caacaacttt atctaagatg cttgagtgac
     6541 gtatttattg tgttttattt tcagccatat gttggcgttg aaaatctgca atttgttcat
     6601 aattctctgt taaagaacga cttaaattga taaaaatgga tacgagctct tggtaaacag
     6661 cgacattttc ttcaaacggc gtatgattat ttgtagcacc gaccatcgat gaaacgattg
     6721 aaaaatcttc aatgtcacct acagctttaa gtccaagcac gcaggcacct aagcatgaac
     6781 tttcataact ttcaggaacc actaactctg tgtcaaatat atctgacatc atttgacgcc
     6841 atacttcact tttcgcaaaa ccacctgttg cttttatcat attaggcgtt tcattcatta
     6901 cttcaatgag tgcaaggtag acggtataca aattgtaaag aacaccttct aatgcagcgc
     6961 gaatcatatg ttctttttta tgagataaag ttaaaccgaa gaatgaacct cttgcatttg
     7021 cgttccaaag cggcgcacgt tctccagcta aatagggatg gaatattaaa ccatctgcac
     7081 ctggtttaac acgctttgca atttgagtta agacatcata aggatcaaca ccgagacgtt
     7141 tcgcagtttc gacttcactc gctagcaact cgtcgcgcaa ccatctcaat acgacaccac
     7201 cattatttac aggacctccg atgacgtagt ggtcctctgt taagacataa caaaatattc
     7261 tacctttgta atcagtacgt ggtttatcta tcacagtacg aatcgcgcca gatgtaccga
     7321 ttgtgacagc aacttctcct ttaccaacac tattgacacc caaattagaa aggaccccat
     7381 cactcgcacc aataacaaac ggtgtatctt cattaagccc cattaatgtt gcataacgtt
     7441 ctttcatgcc tttcattacg tacgttgttg gcactaattc cgggaacatt tccttggaaa
     7501 taccaagcaa ttctaatgcc ccaacatccc aatctaatgt ttctaaatta aacatccctg
     7561 ttgcggaagc cattgaataa tcaatgatat atgtatcaaa taaatgatag aaaatgtatg
     7621 ttttaatatc tgcaaactta gcagtacgtt gaaatacatc ttgccattca tgtttcatcc
     7681 aaaaaatttt cactaaaggc gacataggat gaataggcgt acctgttcgc tgataaatcg
     7741 cattgccatc atgcacttca tttattactg ttgcatattt tgcagcgcgg ttatctgccc
     7801 aagtaatatt atttgttaat ctttgatgtt gctgatccat cgcaatcaag ctatgcattt
     7861 gcgcactaaa tgacacaaat ttaatatcat cttgattaac tttcgattcc ctcattatgt
     7921 atttaattgt cattaatacc gcatcaaata attcatctgg gttttcttct gagacatcaa
     7981 cgtttggtgt gtgtaaatca tagccgattt gatgtttcat gataaaagct ccattttcat
     8041 catataagac tgacttggta ctcgtcgttc caatgtcgac accaatcata tatttcatga
     8101 taaatccttc tttctttcat tttaattcaa ccaaaatcct tcaatatctt taccaacatc
     8161 gtcaaaattt aaatgaaacg cttccttcaa aatttgactg tcgtattgtt ccactgcatc
     8221 aataaacact tgatgattat gatgtatgcg ttcaaaatct tgcgggttct gttgcatacg
     8281 ttgtcgcatg gatgttaaaa cgagtgccat cattactggt tttaaatgac tccaaaatga
     8341 gtttaaatat tggtggttag atgctttgat taatgtttca tgaaattcaa agtcatgctt
     8401 cgtaaatgat tctgcatctt caaattttac tgccactttc atcatttcaa gttgtttctt
     8461 catttctttt acgataggta gtctctcttg atttttaact cttgaaaatg caaatgactc
     8521 tagcatcagt cgcaaatcgt acatttcttt cttttcttgt tccccaaacg gcaacacatg
     8581 tgcacccatt ctttctaatt ggatgagttg attttgttgc aataatttaa atgcatctcg
     8641 aattggcgaa cgactcacat taaattgctt tgccatttga ttttcagtga gtaacgtacc
     8701 ttcagctatg tgaccattca caatacctaa gcgtaattct gccgcgatac cttctccagt
     8761 tgtcatacct tccaaccatt tctctggata tccatacatc atcaaagcac tccttcatta
     8821 catgacatac ttgtatacaa gtatgttaat atagttctta agtgtttgca agcgctttct
     8881 ttatgcgaac taaaatagtg accacccctc ttcgatgtaa atttaaaggg aatgatcact
     8941 atcacacgaa tgatttaatt gttatgttgt atgtgggata tttctaattg ttctgtactc
     9001 atatgcgctt taggtacttc aatgcaataa tgcgtttcat gacagttcgg acattcgaat
     9061 cgacgtgttg tcgctgtatg tttcgctttg ataactgccc acaaagatgg tgagaatata
     9121 tgctggcagt taggacataa ataggcaacc ttttgttggt aataaaaagt aacaccaatg
     9181 ccgtaacaat tcataaatgg taaagcaatt aaaaacggcc atttgttttt catcaagatt
     9241 gaactcataa tgctagaata ttgaattatt cctataatac cagcactaat ccaaatgtta
     9301 cgacgaatac ttttcatttc agctgattta ctcatgacat gctctatgtc ttttaagtgt
     9361 gtgattggag acgtcgacgc ttcatttacg taatattgaa catttttaat tttgtttaat
     9421 accgcttgtt gctgtttgac ttgttggtta atttcttgtt gtttcatggt tagtaaggta
     9481 ttgagtgtct tcaaagtacc ttcacctttt agcaacatat ctatatcgct taacgcacaa
     9541 cctaaatctt taagcaataa gattaactct aatgtttgtc gctgttgttc tgtatacaca
     9601 cgacgctttc cttctgtaaa tccttgtggt ttcaaaatac ctttgcgatc ataatattga
     9661 atcgttcgtg ttgtcacatt gcataatttt gcgagttctc cagtcgaata gttagacata
     9721 gattccacct cctacaatca ccatagttga tgacccgacg tcacgagcaa gtacaatttc
     9781 catattttta agaaatttat tatacttggc gtcttatttt tatgatttcg taccatgttg
     9841 atttacaaaa tcactcaaat taagcaacac tcctactaaa cgtctactct gttatttcag
     9901 aatgaatttg ttgtaattta tcttcaactt cagtaatctc tgtcgcacat tctttcagta
     9961 aatctcgata cttttccgtc tctgcattgt ttttataacg tattttatgt tctaaacttg
    10021 cccacatatc catacctatc gttctaattt gaatttcaac aggcaatacc tcaacgcgtt
    10081 ctgctaaaaa gactggaatg gatacaacga tatgtaaact gcggtaacca ttttctttag
    10141 ggtgctgaat ataatcttta cgttttatca attgtacgtc ttcttgttta agcaacatct
    10201 cttcaatcaa ataaatatca tctaagtaat tacatactac gcgaattccc gcaatatcca
    10261 gtatgtgttc tttggcagtt tctgcactaa tctgtaatcc tttacgatta agcttttcta
    10321 ttaaactacg catttctttc acacgtcgct ccatatgatg tataggattg tgtttataaa
    10381 tgtgattgaa attgtcatct aaaatactca gtttagtgct tatttccttt agtgctgacg
    10441 aataaatatg atctaactct acgaaaccta ataacgtatc aaatgcttca tcaccatttt
    10501 caaatttact taaactattt ttaaaatcat gtcgcaaatc ctctaaatat agtgatggtt
    10561 ttcgatctac atacattttt atactaacct ccgatatata atcatcttta ttgtacctaa
    10621 cattttatta agataatact aatacactat cgaactttgg gctgatactg aaacagcaca
    10681 aagaaactca aacaatccga attatgtatc aaaaccttca attacaggaa gtaattttaa
    10741 aatgatttaa cgcaaaaaaa cacctgttac cgttatatag gtacaagtgc ttaattgata
    10801 gagatgttat acgtctttaa atgattccac aacttttgga tgtgcaccat ccataagcgg
    10861 ttctctttgt cgaacgccac cactttggtt gccaattgat tcgctatcaa agtacgattt
    10921 atcttgattt gattgttctt gaatatgttc ttcattatca gttgttgcat attcactatc
    10981 cacctctgct ttttccattg ttgctgtatg gaattgtacg aagttctctt cttctaatgc
    11041 tttgatttct tctttcgata acgctcgata ccaatctttc gcttttttcg ccgcaatagg
    11101 aacaacatct ttttcaagat atccttcttt taacattgca ttcgcaattt ctatcgcttt
    11161 ttgccgttta attacttcaa attctttcca tttttcgggg taacctttca ttgtaaaggg
    11221 catttcctta acctccaata tgttataatt catgttatat accaccataa ttataaaatg
    11281 aaacatatta aacacaattt tttagactcc cgtcataata acttcagaca aacgttagtc
    11341 tgacctgata aatattttat tttaaacgtt cttgtctctc tcacgaaaac cattgtgttg
    11401 aatattcatc attgctgatt gaatataatt atactgtggt aaatctggta atatctttat
    11461 ttctaattct gtatttaatt ctaaatgctt agcgatgttt tcaaatgttg ctaaatactc
    11521 gcccattaat tgttcattta ttgtaagtct atcttcatta gccatggctc tatttaacat
    11581 aaagctaatt tcttctaatg cgaataagct aggataataa ttttgaatca atgtcttatc
    11641 actaaataat tcaccattag ctgcattata aacttgcgtc atgttattta atttcacaga
    11701 taggttcatg gccgtgtttt tctgatacac attatcttta tattggtttt cagaaaacaa
    11761 ataatggaag agcgttgctt ctttacgaac aacttcagcc attacattag gaagcaatac
    11821 ggatgcggta cgttgtccaa ggacaaataa acctatgatt gcaatcacaa tacctattgc
    11881 aacgtcaata actcttggaa acgcaatgtt aattgttaaa ttctgtgatg ctaatccatt
    11941 cattaaaata acttgtattg taataaaaac tactgcaatc gcataatttg ctcccaccaa
    12001 tgcttcagta aacaatgctg caatgcccat taaaattact gcaacaggtg ttggtattga
    12061 aaacaacaat atgactgaaa gtactaacac acctaaaata gtacctaaac ctcgtgccat
    12121 acctctctcg attgcatgta tagttgatgt tcctagtaat attgtatgtg cagataacgg
    12181 tatccagtat gctttttcaa aatcaaacat taacgcaata aatatcgcta tcatcataat
    12241 cgctgtatat ctcaatgtat ttctaaaaac aatagagtct aatgttaaat tttgataaat
    12301 gcgtttacta tataaaggtt ttcgcatgtc tgcttcatac gcaatacgcg cttcatttgc
    12361 atgcaccatt tcatcaattt tcaatatatg gttgaataaa ttttgaaatt cctctgttac
    12421 tgtcacttct tttcgccaat atcttacatt ttcatcacta ttatctagtt gtgcaatgat
    12481 atgatccatc atttcaatta actcatctgg caatggtcga atttgtttag cgttcaactc
    12541 taacagttca gaataaatcc cttgggcaga tgtgtgtaat aataataatt tttggaaacg
    12601 tctacttaat ttatcgttac ttgaagtaga agtgattaat aatttatcag atgctttaaa
    12661 actatccacc gctgtttttg ctacttgtaa aaaagcagct ttatcattat aagtgtgtaa
    12721 caacttagat atgagtttaa aatcattttg aattgcttgt tcttcagctt tgtttttaga
    12781 aaatacgatc gtgattaaca ccatcatagt ggcaagtata ccgcctacta aaatcgcaaa
    12841 gcctctatat aatgcttctt cgggagctat aggtaagtta atgggtagac tgaatgtcac
    12901 aatgaagaat gtcgatgacg gtccagctat ttttaaggca gtaaatatat aaaatggtat
    12961 aaccgtaaca attaataatg tcattccaaa aacgagtggc gttttggctg ttagcgtacc
    13021 aagcatcata catattgcaa acgctaaatt acaaattatt acagttcgca gcttagatcg
    13081 cgacggacct ttaaaaacat aaatatgggc tagtgttccg gttgcaacta ataatccaaa
    13141 ttggaaatta ccacataagt aaccgattat tgcaggaata atcattaaca gtccctgtct
    13201 tacaccttta taaaagtcta agttaagtcg attgattttt ataagtgatg tcaaaaagat
    13261 gtcatttcga cttctccttt ccttgtcaaa atatttccat aatcttttta ttagcatagt
    13321 taaaatgaat ttgttgctat aaattttaat tacgcaacat atgtgattat aacaccttat
    13381 gctcaattat ctaaatttaa aaacttttaa agtccaatta aaattaattt ctaatgttat
    13441 ttaacatcgt tgaacctttg gtcgcccacc tttgggctag ttaaaattta tatgtacttt
    13501 tacaagcgtt acctgactaa tgttttaaaa ctttatttct ttacatatat cattttaata
    13561 acttcccgtt catcttaaac catatctgtt ttaaaaagtt tcaatttcaa cgtaaaaaag
    13621 caataagccc caacaatgtg aaagcttact gcttgtttaa attatttttc tattgcttta
    13681 tcatcactaa caattaaagg ttgatctggt ttcacataga accacataat cacagcgatt
    13741 actgctggaa cgattaacaa ttggaatgtc attgtccaac ctaaatgttc tacgaataga
    13801 cctgctaata gcggactgat taatgcacct atattacccc ataagttcat ccaccctgat
    13861 actgtaccag agaagttacg tcctaagtca gttgctgcag cccaactcat acccattgaa
    13921 ataccgatac caccaagacc tagtgataac cagaaaatac ttacatataa atttcctgta
    13981 cgtacagcaa agataattga aactgcaaac acaataaatc ctgcgattgc aattacacct
    14041 ctagctacga attttgaacg acctaatcct aatacacggt cagaaattgc acctgctgat
    14101 aagattaaga agaacattaa taaccaaggt aatgaactaa tgctcatttc tttaaagtta
    14161 acgtggaata cttctgttaa atacgtcggt aaccaaatta agaataatgt aatgataaat
    14221 tgtacaacaa agtattgaat tgcaattgca tagaagctaa aacgtttaaa gaaattattc
    14281 catggtggtg atgacttttc agtagctacg atatcacgat tttccataat gaaacgtttc
    14341 tccgcttcat taaccattct atgttgctca ggtaagtctt tggcaataat cgcccataat
    14401 acagccatta aaatacctac tgcaccaaaa atgtaaaata ctgcttgcca gttaaatgcg
    14461 ttaacaatag caattgtaac tattggtgct aatacaggtc cgaaatatga tcctgctaat
    14521 aatgcacttg atgctctacc tttttcattt ttagagaacc aaaatgagtt aaacacagca
    14581 ttagaaggat acattggcgc ctcacccaca ccaaataaga atctcactaa ataaattaaa
    14641 ccgtggttct taatcatacc cgttaagatt gtaaatgcac tccaccaaac taatgcaatt
    14701 gtaatcatct tacgtggacc gaatttttca gccaacatcc ccgatggtac ttgcattaat
    14761 gcataaccta gagagaagaa tgatgccaat aaaccaaatt gtggtttggt catccctaaa
    14821 tcatccatca tttgtttagc gatatatgaa atgtttgctc tatccatata cgcaataacc
    14881 ccaataaaga agaacgcaag cgcgaacatc caccttacgt tagttcgttt ttccttcata
    14941 actattccta cttccctaat taatttttta aaacttaccc tgaaacgtta aaattttcgg
    15001 acatctggca tgtccacccc tactttgtca caaaattgta ccaaagttat tttttataat
    15061 attatcagac atggaaagcg tttacaatag aatctataaa aattttatta aattccgctt
    15121 aacttttgct attaaaacga tataaaggaa cttttagtta catagtagcc tatcatttgt
    15181 taattaaaaa tactgcaatc ctagtgtttt aaaacgtata ttgcaggctt tcttacatat
    15241 tcgacattca ttttaaattg cataaaacta cattgctcat tcattgtgca gcgcctgtta
    15301 tttagatgat catttgttga cttttcgtac ttatagcaag caattttttg atttattgct
    15361 tataatacat tttaagacaa atgcttgttt caacatcgca tacgacatca ttcattattc
    15421 atttgaattt atccagtttc tatttgtctg caattgctga aaattaaagg agcttatttt
    15481 taataatgga acaaattatc actgaattta ttagtcgttt tgggtatgca gccattttta
    15541 tattaatttt attagaaaat gttttaccta tcgtaccatc ggaaattatt ctgacatttg
    15601 ctggccttat gtctgttaaa tcacatttat caattttaac cttatttatt attgcaacca
    15661 tcgcatcgtt tatagggctg ttaattttat attatatctg ccgtttgatt tcagaagaac
    15721 gtctatatcg ttttattgat cgacacggta agtggattaa attgaaaagt aaggatttaa
    15781 agcgagcaaa tgattggttt aaaaagtatg gcgtatgggc tgtatttatc tgtcgtttca
    15841 tacctgtatt acgtgtattg attaccattc cagccggtgt aaaccgcatg aatgttgtga
    15901 catttaccgt tatttcatta ataggtacaa caatttggaa tttcggttta attttactag
    15961 gacgcacgtt gagcgatagc tttggtatgt tgatgactgg tcttcataca tattcacgta
    16021 ttatgtatgt tgtcatcatt atcgcagtca tttactttgc tatacgttac attggcaaac
    16081 gtaagagagt aaaataatat tgttgttagt ataaaggcat gaattttaaa tttctataca
    16141 caaaaagcag taaaatcatt ccatctattg aaatgattca ctgctttttt aagtttattt
    16201 ggcatacttt agctgaaagt cacctaaaat cctttacgtt aagagatata atgaagtttc
    16261 ccatcaaagt tcagttccct cagtatgtat acattccgca aacttatctc acaaatccat
    16321 ctataataca aactatcatc ttaaataaac agaatttacc ctgtcctcca cacaaattgt
    16381 tttcgacact ttaatgtgcc tactatccaa aaaagttact cataacaaat tgcgcatttt
    16441 aataaatgta gcaataccat ttgcacgcta caaaaatact cgtgttcata tttatatttt
    16501 atattattaa agttttttaa atccatattt ttataacact tgctatgtga taaaattaat
    16561 tttatatata aaatcttaag attcagatta tttaatagca aaggagatag tgatatgggt
    16621 gttttaacaa tagaacattt aacaaagaag ataggcaaca aaacgattct cgaagatgta
    16681 tcatttaagc tgaaacgcgg acaaatagtt ggtctcgttg gagcgaatgg tgcaggtaaa
    16741 acaactttaa tgaaagttat attaggttac tctagtttcc aaagcggaaa ttttaatgtt
    16801 attaacagca aagacagcaa aagcaatatc ggtgcattga ttgaaaatcc aggaatatat
    16861 ccttttatgt ctggatatga aaacttgaag ttattgaatg aatcaaaaaa cactcaagat
    16921 atcgataaaa ttgtctcaca acttcatatg gatgaataca ttcataaaaa agctaaaacg
    16981 tattctcttg gtatgaaaca aaaattagga attgctatag catttttaaa tgaacctcaa
    17041 ttcattatct tagatgaacc aatgaacggc ttagatccaa aagctgtgcg agatgtacgt
    17101 gaattgattg tccaaaagtc gcaagaaggt gttactttct taatttcgag tcatatttta
    17161 agtgagttag ttaaaatcac aaactctatc cttattatta acaaaggtaa aattgttaca
    17221 gaaacatcgg aagaagaact taaacaattt aaagataatg atttagaaaa tgtattacta
    17281 gaaatcatag aaagggagga ccaagcataa aatgggaact ttaattaaac aagaatgttt
    17341 caaattattt aaaaagaaat caacttttat cgcacctatt gtcttcattc tactaatggt
    17401 tgctcaaggt tatatcgcta caaaatacaa tgaaattttt acgccacagg aatctttcac
    17461 atctgcttat aatggttttt catggtttgc atttttatta attattcaag caagtacaat
    17521 catttcaatg gaatttcatt acggtacgat taaaaattta ctctatcgtg aatattcaag
    17581 aacaactatg attgttagca aaatcatcac attatttatt atttctttaa tttattttgt
    17641 tattacaatt attgcttcaa ttgttattgg gtctttattc tttaatgatt taaatatatt
    17701 tgaaagtagc ggtaatcaat tatctttatt gaatcaatta ttattagtta gtttaggtac
    17761 atttgttggc gtttggttag ttttaagctt aacgttgcta ttatcatctg caactaattc
    17821 aacgggtgta gccattgctg taggtattgt tttttatttt gcaagttcta ttttagcagt
    17881 tattcaaacg gcacttttag aaaaaataga ctggctaaag tggaatccta ttaatatgat
    17941 gaatattatg cttcaaacag ttgaaaaagg ctttagtaag tcgacgaaat tagaacttca
    18001 tgaattgttt attggtaata ttgcttatat ttctattttc ttaatacttg tagtatttat
    18061 tttcaagaag aaaaatattt agtaacttaa agtattagat gaataaatac acacatattc
    18121 catcgtaatt caaaatcatt ttcaaatccc ttcacccaaa taatggtgcg gggatttttt
    18181 tatccaaatt ttggcaattc cacattttac atatcgtaat tttttaggaa actagtgaat
    18241 ataacaaatt cctcctctca tttttaaaat aaatatatca ctttcccact tttacttaac
    18301 taaactgcaa cgactcctaa taccaaaatc ctgccctcta tttttatcaa tccaagcata
    18361 cttattgaaa aatgttaacg ttttcttgat aatcattgta agcgcattta ttttataaac
    18421 taacgtttga aatatactac aggagtgaca cgtaatgact caaattactg aaaaagaatt
    18481 aaaaaagaag tatttagatt tactatccca aaattttgat actccagaaa aacttgcaac
    18541 tgaaattatc aatttagaat caattttaga attacctaaa ggtacggaac atttcgtcag
    18601 cgatttacat ggtgaatacg aagctttcca acacgtatta cgcaacggtt ctgggaatgt
    18661 gcgagcgaaa atcaatgata ttttcaaaga gagactttca actaaggagc ttaatgattt
    18721 aactgctctt gtctactatc cagaagacaa attaaaattg attaaaagtg atttccaaag
    18781 ttgcggtcaa cttaatgtct ggtatatcac aacaatcgaa catttaattg agttgattaa
    18841 atattgttct tcaaaatata cgcgttcaaa actgcgtaaa gcattgccaa aacaatacgt
    18901 ttatattatt gaggaactac tgtataaaag taatgaatat caaaataaaa aatcatatta
    18961 cgaaacactt gttaaccaag taattgaact taaacaggca gatgatttaa ttattggact
    19021 cgcttattcc gtacaacgct tagtcgtcga tcatttacac gttgtcggtg atatttatga
    19081 tcgtggacca caaccagata aaattatgga tacactgatt aattatcatt ccctagatat
    19141 tcaatggggt aatcatgatg tgctttgggt tggagcctat gctgggtcaa aagtatgctt
    19201 agcaaactta cttcgaattt gcgcacgcta tgataattta gatattatcg aagacgctta
    19261 tggcattaat ttaagaccac tgcttacttt agctgaaaaa tactatgacg cagataatcc
    19321 tgcttttaag cctaaaaaaa gacctgacaa acacgaacgt ttaactcaac gtgaagaaag
    19381 tcaaattact aaaattcatc aagctattgc gatgattcaa ttcaagttag aaataccaat
    19441 tattaaacgt cgtccaaatt tcgaaatgga agaacgtctt gtgcttgaaa aggttaatta
    19501 tgatacaaat gaaattacag tttatggtaa tacatacccg ttgaaagaca catgtttcca
    19561 aactatcaat cgtaataatc cagcagaatt actacctgaa gaagaagaag tcatgaataa
    19621 actattattg tcattccaac aatctgaaaa attacgtcgt catatgtctt tcttgatgcg
    19681 taaaggttcg ctttacttac catataatgg taatttactc attcatggtt gtattccagt
    19741 tgatgaaaat ggtgagatgg aatcatttga aattgatggt catacttaca gcggccaaga
    19801 attattagat gtgtttgagt atcatgtccg taaatcattt gatgaaaaag aaaatactga
    19861 tgacttatcg acggatttag tttggtattt atggactggg aaatattcgt cattatttgg
    19921 taaacgcgcg atgactacgt ttgagcgata ttttattgca gataaagctt ctcataaaga
    19981 agaaaaaaat ccatactatc atttacgtga agatgtgaat atggttcgta aaatgctcag
    20041 tgatttcgga ttaaatccag atgaaggacg cattattaat ggtcacacac cagtgaaaga
    20101 aatcaatggc gaagatccta tcaaggctga tggaaagatg cttgtcattg atggtggttt
    20161 ttcaaaagct tatcagtcaa caactggcat tgcaggctat acattgttgt ataattcatt
    20221 cggaatgcaa ctcgttgcac accaacaatt taacgctaaa gaaaaaatac tttccgaagg
    20281 tatcgatgaa ctttctataa agcgcgttgt agacaaagaa ttacaacgta agaagattcg
    20341 tgataccaat attggtaaag agcttcaagc tcaaatagat attttgaaaa tgttaatgca
    20401 tgatcgttac ttagactaaa gacgacattt tatgcatgta ttgtatactg ttgtattgat
    20461 gcggtttacg cattggctac gcaaacgcga tgataaatag gcgacctagc tacaccgaaa
    20521 aaaatcccct cactattgcg agtagtgagg ggattggtgt atctatgcta attcctgtta
    20581 actgtattat aacaacttta cagcaaaaaa atgcaaaatc aactaataaa ttaatgaaat
    20641 gaccgacgcc ctcgcttcta cttcaattta acaaaatact atattagtac tatatttttc
    20701 attaacatgt atgttacatt ttctatatta cttaaaatta cgaagggaca tttttaaatc
    20761 atgcgtatct taaaagagtc cattattgtg gcatttgcct ttgttggtgt tgtcgttggt
    20821 gccggctttg ctactggtca agaaattttc cagtttttca caagtcatgg cgcatatagc
    20881 atttcaggca ttattgtaac aggactattg attactttag gtggaatggt tgtcatgcat
    20941 acaggtcatc atctaaagtc cagaaatcat tctgattcaa ttaactattt cttatacccc
    21001 tctattgcaa gaggttttga tattatttta acaatgttta tgttgtcttt agctattatt
    21061 atgactgcag gtggtgcgtc aaccattcat caaagtttca acttaccgta ttggctgagc
    21121 gcactcatat tagtcgcctt tattttagca acactgtttc taaaattcga tcgtttaatt
    21181 gctgtgcttg gtggagttac tccattttta attgcaattg tcattatgat tgcggtctac
    21241 tatttcacaa cgagtcatct tgattttact gccgctaata atgatgctca gattcataag
    21301 cagaaatcat tatcacctgg atggtggttt gatgcgatta actatgcaag cttgcaaatt
    21361 gctgctgcct tcagcttctt atcagtgatg ggtagcaaag ttaaatatcg tgactcaacg
    21421 ttatacgggg gcttgattgg cggtttaatc attacatttt tactcatgat gattaaccta
    21481 ggtttaattt ctcaattcga taaaattaaa cacgtcgatt tacctacatt aaaattagcg
    21541 acacaaatgt ctccgtcaat tggtattatt atgtctgtca ttatgatact tgtcatctac
    21601 aatactgttg ttggattaat gtatgcattt gcgtcacgtt tcagcgttcc attcagcaga
    21661 cgttacttca tcattattat tacaatggct gtcatcactt atattagtac atttatcggt
    21721 ttcatttcat taattggaaa agtattccct attatgggat tgttcggttt catcttactc
    21781 atacctgtac tctataaagg tttaattaag cgtattaccg gcaaatctca tatcgattaa
    21841 aacatctata ctattgtaaa atttattaca gcacttcaaa atcaaaaaag cgggcagatg
    21901 aaaagtaaaa atcttttcca tctgtccgct tcttaataga actgttattt cccaagtatt
    21961 tgttgaccag ccgttaatcc agtttctgta atttcatgac cattcaccca aacttcttcg
    22021 actactgccc cacgtgtctt aaacaagtta atgacttgtt cacttgcagc taatggcaca
    22081 attggatcat gtttccccat agaaagcaac acacttacat ctgataaatc ctttgttgac
    22141 gttacttcaa ctgggtataa cggtgcatat aacaatgctt ttttaaatgg tgcttccgaa
    22201 cgcaacatta agttaatcgc tatatttgat ccatttgaaa atccaacaag tactgctttt
    22261 tcaatatcaa attcataacg ttcagcagct tctttaatga acgctaacaa ttcttgtcca
    22321 cgaaattcca aatcttcttc atcataaaca ccttcaccaa gacgtttgaa ataccggttc
    22381 atcccatttt ctgaaacttg tcctctaata cttaacaagt gataattttc attcaatgct
    22441 tcgcctaatg gcaataaatc gaattcatcg ccacctgtac catgcaacaa tattagcgtt
    22501 ggtgcacctt tttgtccttc acgaaaaata tgttccatca caaatcctcc tcattccaat
    22561 taatcatgtt aacgcttagt attaaatggt cttatttctg attctatata ctctctttta
    22621 ttttctaaaa atggtggcaa tgataaacct tcacctaatg tttcatacgg ttcatcttcc
    22681 ataaatcctg gtccatctgt tgaaatttct attaaaatat gccccacacg tgcatataat
    22741 gcttcaaaat agaaacgatt aacgatgcct gagttgttaa tacctacctc tttatatttc
    22801 gttgcccacg cttctattgc atcatgatct ttcacacgaa atgacacatg atgtacctca
    22861 ccataacctt gacgtgctgc tggcccttta tcatctttta ttaagattac ctggccacca
    22921 ttgccgcctt cgccaacttc aagtaatgcg acattatctt catgcgcaat agttgtcata
    22981 ccgtaaacag tctctaaaat atttttaaag tcgtcaaaat aacttacttt aatttcaatg
    23041 ggtcctaatc cataaatcgc tttatctact ggaaccggtc cattcttcca aggtacacca
    23101 ggtgctaccc catcatttaa ctcatctgaa attaattgat acacttggcc atcgacttct
    23161 tcaaatggca acactttttt accaaataat tcttgaatac cttcgtgttt aacaccaaat
    23221 tcatcaaagc gctgttcata atacattaat gcgtcatcgt taggcactct aaaagacggt
    23281 cttgtaatgg aatttgttcc tgcctgccct tttgtaatat ttggaaaatc aaagaatgtc
    23341 atatctgtac ctgctgaacc tacatcatct gcaaaaaatg tatgatacgt ataaatatca
    23401 tcttgattga ctgtcttttt aactaaacgc atgcctaata cttctgtaaa aaatttataa
    23461 ttacgttctg catcatctgt cattgctgtg acatggtgaa tacctagtaa ttcatgatta
    23521 tttatcattt tatataccct ctttatattt ttagtgtatt tatctcgaaa tcgagatatt
    23581 ttaatgtaaa tttttagtgc acgccttaca cttctgtaga ttgtgcactt agtttcttaa
    23641 acgcttgttg taagattgtt aattcatcct ttgttaacac atcaaacgct tttgttaatg
    23701 tctcagcatg cttagggaaa atatctgcca tttgactttg acctttttca gttaaacaag
    23761 ccatatatac acgtttatca tctttatcct tttcacgtgt aatccaacct ttgtcctcta
    23821 attgacttac aacatatgaa atgctgctac ttgcaattaa tacgcggtct ctaatacgtt
    23881 gaattggttg cggaccttta ttataaagca actcgagcac tgcaaattca gtaatattta
    23941 agccatatcg ctttacgtct tcttttgtaa tttgctctaa tgtgtctaac gccctattca
    24001 ttccgacaaa gacattgagc gattgtttcg ttcgatccat atcatcacca actttttaat
    24061 ttatttcgat ttcgagataa attatatagc tgaatggatt taatgtcaag atacgtgttt
    24121 tcatctttat ttcaaattgc gcttaataaa aacgactaca taaatgcggc aatgtcgtca
    24181 catgactgtc atgcaccttt tacttcgttt aagttaaaat agaataggga aatattataa
    24241 tcaaacatga taggagttga tatgtatgag taaccttgaa atcaaacaag gcgagaacaa
    24301 attctatatt ggtgatgatg aaaataatgc tttagctgaa atcacatacc gttttgtgga
    24361 taataatgaa attaacattg atcatacagg cgtatctgat gaacttggtg gtcaaggtgt
    24421 tggcaaaaaa ctagttaaag cagttgttga acacgctcga gaaaatcatt taaaaattat
    24481 tgcctcatgt tcatttgcca aacatatgtt agaaaaagaa gattcatatc aagatgtata
    24541 tcttggttaa ataaattttg cgatggtgca actgtaccat cgcttttttg ttcgcatcaa
    24601 tataaaattg caaaacgact agttattttg catttcaaac tttatgctat caattcattt
    24661 tcttttctgg tatacttttt atactaactt atagaaaaat agaaaacgag gcgatgcata
    24721 atggcatttc acgataaaac agcaacacaa gtgacaaaca ttgaactgaa cgtaagagac
    24781 ttagacttaa tgacaacatt ttacaaaaac attttaggac tatccgttaa aagttctgac
    24841 gataacacaa ccgtattatc tgttgggact ggtggccata ctctaacgtt acatttatta
    24901 gaagacggcc gtcagacttc cccacgtgaa gcaggacttt ttcatatagc atttttatta
    24961 ccaactactg aggatctagc taacttctta tatttcgtgg cacaaaaaaa tatgggcatt
    25021 ggcgctggtg atcatttagt aagtgaagct ttatatttca acgaccccga aggtaatggt
    25081 attgaagtct atcgcgatag accttcatct tcatgggaat ggcaaaatgg caaagttaaa
    25141 atggatactt tagaagttga tagccaaacc ttattaacac atcgtactga tgaaggttgg
    25201 caaggaatgc cagcaaaagg catgattgga cacttacatt taaaaacaca tgatttagac
    25261 gcagcatatc aatgttacat tgaacaatta ggattccaac atgtgtctga ttttccacgt
    25321 gcgctattta tgtcaacgaa tcattatcac catcatattg ctgctaatac ttggcaatcc
    25381 aatcaagcaa gacaaaacaa tgcacaaagt tatggattaa cacatgttga tatttatcaa
    25441 cccgacgcct caacacatac atttacggca ccagaagggt ttgacatcac agttcattca
    25501 aatactgacc ttgttccaga aaaataatca tccatacttt attaatacaa ttttttcacg
    25561 caaaaacctg cgattcattt atgtaatcgc aggctttttt tattgctaac tttttaattt
    25621 tatatattta gacatactgt attctattta ttcttttggt ccaacccatt caataacatc
    25681 ttcatatgct tggcgtgttt tatttttcgg tggatcttgt tgtctgtagc caaatgcaac
    25741 catcactgat aaaccaaatt gctcagtatc taagatacct ttatttgcta aaatgtctgt
    25801 cactgtatcc agactaaaac cttccatcgg acatgaatca atacctaaca atgcggctgt
    25861 cgtcatcata ttgcctaatg cgatatacgt ttgtttactt gaccagtcat acaaggcttg
    25921 atcattatca gaaatatgga aatctgcttg gaatgcatcg aatttttgtt caacagctgg
    25981 gatcgtttgt gcctcatatt ttttaatatc tcttaacata tgttgtacat acggtgatct
    26041 tgacgttaca tttttacgcg caaaaattag cacaaaatgg ctcgctgtat ctaattgttt
    26101 tgctgcgccc caactgtgcg cttttaattc atcacgtaac gcttgatctt gaatcacgac
    26161 aaacttccaa ggttctaacc caagagaact tggagacaat ctacctgact ctaatattgt
    26221 ttcaaaatct tctttcgaaa ctttcttttg tggatcgaat tgcttagtcg catgtctgaa
    26281 atgaaatgca tccataattg tttgattcat attgctcatt gaacatagcc tccaattttt
    26341 atatttatta ctatacaaat tatacttcat gttttaaaaa gactaaagta atccgtttgc
    26401 aattcgctat aacttgtgca catgttataa gttttctgca ataaaacaca cttttgaatt
    26461 ttggaaaatt tagtgttata atatatttgt gatatttttc acaattaaat tgtggcgtga
    26521 ttttaatgta cataatcttt aatttcactc atttactttt caatctttta aaagcgaggt
    26581 ttttaataat gacaaaaatt atgttctttg gtacgcgtga ttatgagaaa gagatggcat
    26641 taaattgggg gaaaaagaat aatgtcgaag taactacttc taaagagcta ttatcaagtg
    26701 ctacagtcga tcaattaaaa gattacgatg gcgtaactac aatgcaattt ggtaagttag
    26761 aaaatgacgt ttatcctaaa ttagaatctt acggtattaa acaaattgca caacgtactg
    26821 ctggatttga tatgtatgat ttagatttag ctaaaaaaca caacattgtg atatctaacg
    26881 ttcctagtta ttcacctgaa acaattgcag agtattctgt ttctatcgcc ctacaattag
    26941 tgcgtcgctt cccagatatt gaacgccgtg tacaaacaca tgattttact tggcaagcag
    27001 aaatcatgtc taaaccagtt aaaaatatga ctgttgcaat tatcggtacg ggtcgtatcg
    27061 gtgctgctac agctaaaata tatgcaggat ttggtgctac aattacagct tatgacgctt
    27121 atcctaataa agatttagac tttttaactt ataaagatag tgttaaagaa gctattaaag
    27181 atgccgatat tatttcttta catgttccag cgaacaaaga aagctatcat ttattcgata
    27241 aagcaatgtt tgatcatgtg aaaaaaggtg caatcttagt taacgcagca cgtggtgcag
    27301 tcatcaatac acctgattta atcgctgcag tgaacgatgg tactttgtta ggtgctgcga
    27361 ttgatactta tgaaaatgaa gctgcatact tcacaaatga ctggactaat aaagacattg
    27421 acgataaaac attattagag ttaatcgaac atgaaagaat tttagtaaca ccacatattg
    27481 ctttcttctc tgatgaagca gtacaaaacc ttgttgaagg tggtttaaac gcagcattat
    27541 ctgtcattaa cactggtaca tgtgaaacac gtttaaatta atatatattt aaaagcaaag
    27601 gcgcaccatg tgcctttgct ttttattttg tttatctgta tcaaaatcgg tttgattaaa
    27661 atctgcttta ttttatcatc tattcaactg attgtagtgc gcttatttta ctatggcatt
    27721 attgcctaac ctgtttgaga tatattaatg tttgatgatt cgtattcaaa gttttcattt
    27781 aacatgtatt tagtatcatg atagccgctt cattgatgat gtgctaccta cttgttcaat
    27841 acttcttgtt cgataatcgt taaaacaccc tgcttatcat tacttggagc gacagccgag
    27901 gcaatattga acaattcttc atcatgacta ttttccatca cataactatg cttagcgaac
    27961 gctagcatat ctttatcatt attcgcatct ccaaaggcca tgagctctga aggagacatt
    28021 tcccatttat ctaacaatcg ttttaatgcc tgccctttag tcatgtttgg cataataata
    28081 tcaatgctat cgtgcccact tgagacaagt ttaatatcat tgctgaattg cgttgctact
    28141 tcttcgtcaa catttggatg cgtctcacga ttaatattaa atgctatttt gacataatca
    28201 tcctcaggta attgttgtag actgtcaatt tcttttaact gatgataata aaatctcgta
    28261 tcttctttaa atgcttcagt agtatgtttt aaaatatacg cgcttttcaa accacagatg
    28321 acgagttgat caatactttg gttcatattt aagtaatcga cgacctgttg aaacacctga
    28381 cgattaaagc ttttataatt atataactca ttgcctttat aaataactgc accattttca
    28441 gaaataaaat acatatctct atccccgaaa atagacttca acttcgcata ttgattgcca
    28501 ctcgcagcaa taaatgtaat atctctattt ctaagttcag taaaaatcgc ttcaaatctc
    28561 ggtttatcgt atgtcttttt cgaatctaaa aacgtcccgt ccatatctac cgcaatagcc
    28621 ttaaccatga ttatcctcct cattgctctt ttagtcgtct tcattatatc catctcatga
    28681 caagcaatga agtttgtcat accacaatga aactatattc acattttgaa attgctttca
    28741 tatatgcaaa acacattaca ctggatatag cattcggagg cgaacataaa tttcagaata
    28801 ttgtaaaaat ataacgatat atttatcatt tggacaaaat atagtgtgat atactaattt
    28861 ataacatcta tacataatgt gaaaaaattt ttaaaataca attaaatatc ggtgtaataa
    28921 atccctttat acataggagt tgtatacatg aaactaaata actattcttt aaaagttaaa
    28981 aacaaacaac tagttgacaa ttgtgattta aatttctatc ttggtcagat caatcacatt
    29041 gttggtaaaa atggtgtagg aaaatcttta ttagctaaag atttcttact aaataatagt
    29101 ggaaatatcc ctaagtccat ttctcaaaat gtaaccttaa tatcaagttc atcaaatatt
    29161 cctaatgata taacaaaaga ttttttatta tcattgttaa aatcaaaatt tgaaaacaat
    29221 cgacaaacat tcgataagat ttataacata ctaaacatcg aagcaatacc gtctaacgta
    29281 ctactaaaaa acttgagtga tggtcaaaaa caaaagctta aattattaag tttcttattg
    29341 gaagatcatg atttaatcat attagatgaa gttacaaacg ctttagacaa gaaaacagtt
    29401 aatgaaattt atgaattttt aaatgatttt attcaaagcc atcaaactaa aactattatc
    29461 aatattacac ataatttatc cgatttaagt gctttgccgg gtaaatactt tatttttaaa
    29521 gaccttcaaa tagaagagta ccaatcaaaa gaagaagtca taaatgatta cattaattta
    29581 taattgaggt gtccactttg aaattagaat ttaaaaaaag tatttccaat aaaattattt
    29641 acacgcttgg tgtgctattc atattccttt tcttacttgg gtatttttta ccaataggaa
    29701 tagacaaagt taaaaattta agctatggtc agtttttctt tagttcttat acagttgcca
    29761 ctgaatttgg ctttttatta ttttcatttg ttattgcata ttttattaat aaagagtatt
    29821 cgaataaaaa tatattattt tacaagctga ttggcgataa tatatttacc ttcttctata
    29881 aaaaagtagc agttctattc attgaatgtt taatttatat tattttaggc atcacaatta
    29941 tttcaataat atattcggat ttctcacatt acttactatt aataatctta ttttcactcg
    30001 ttatcttaca atatatctta gttgttggaa cgattagtat ggtttcacct aacattttaa
    30061 tcagcttagg tatcagcatt gtatattgga ttggttcagt catcttagtt gccattaata
    30121 aaaatatatt tggtatcgtt gctccgtttg aggcgagcaa cacgatgtat cgtgccgtag
    30181 aaaaaatatt gaataacgag tcaacattta tatgtcctac tgaaattata aatacagtat
    30241 cattcttcgt tcttctattt atagttaata ctattgtctt attactaagt agaaagagat
    30301 ggttgaaaat cggtatgtag tacataaaaa agagcggcat ccattgtcgc tcctttttat
    30361 tatgtatttt tacaatctcc accaatgaca cgtcgtcatt ggtgcctcac accaaacaaa
    30421 aaaacagtct cgcaatcaag actgttttcc actcaatata ttcatccatt agcgtaatgg
    30481 attatttgac ttctgtagct acaaagattt tacgtttttc ccaaacgcct gtcttttcat
    30541 tgtaatcatc acaagtaatt aatgttaatt gtttatcttt acctttttgt tcatctagaa
    30601 cttctacatc tgttggctta acatctctta tacttgtcat tttatactta cgtgtttcat
    30661 taccaacttt aaagtacacc atactacctt ttttggctgc tttaagattt gtaaattgat
    30721 agttcggacg gtcaatgaaa gtgtgtcctg caattgaaat attttgatca tctagtgatt
    30781 cattttcttc tgcaaagctt acacctctat ttaattgttc aggtgttgct ggtcctggat
    30841 atactggttc tttaatatca gcatctggaa tttcaatata gcctgccact tttgatttat
    30901 ctttcggaat ttgaggttta gcttgctgct tattgtcttt actcgcctgt tcttttacat
    30961 ttttatcata ttgttcaatc ttttcatctt tatctttatc gtgaagataa ttatcgatat
    31021 gtggtttagc aaacaaatat gctgccacta ggataagtac tacaccagcg attgtcatta
    31081 atcgatttgt ccattttttc atacgttaag gctcctttta tacatttcac aatgcctatt
    31141 aacatttcat atagtatacc attaattata aaatgactca tagcaattca ttttatatta
    31201 taaaatttgc acatatattg tcacgttaga tttcattaca catatttgca ttcaaataac
    31261 gaaacgtttt taataattac taagggggaa ttattatgat tcgatgtgct aaaaaagaag
    31321 atttaaacgc tatattagcg atatacaacg atgccattat taatacaaca gctgtttata
    31381 cttataaacc gcaaaccata gacgaacgta tcgcatggtt tgaaacgaaa caacgtaatc
    31441 atgagcctat ctttgtattt gaggaaaatg gaagtgtatt agggtttgcg acgttcggtt
    31501 cgtttagacc ttggccagca tatcaatata ctatcgagca ttctatttat gtcgatgctt
    31561 cagctagagg aaaaggtatc gctagtcaat tattacagcg tttaattgta gaggcaaaag
    31621 ctaaaggtta tcgtacactt gttgctggta ttgatgcttc taatgaagcg agtattaaat
    31681 tacatcaaaa attcaatttc aagcatgccg gcacactgac caatgtaggc tataaatttg
    31741 attactggtt agatttagct ttttatgaat tagatttaaa agactagtag tgtttaaatc
    31801 acataatata aacaagacaa ccatgttaat tcacttaaca taacatgcta acatataaaa
    31861 ctataaacct cttagggaca atttacatcg tccctttttt catttcaaat actatcccca
    31921 tagctttgat ttaacgcttt ttctcaataa caaaacgaat atagtagaac atgaaaacga
    31981 taatcatgct gagcgataaa gatttaaata atagattgac ccacgttccc tcagtcgtat
    32041 atccatatgt aatcgttgtg ttaatgatga atgctataaa gatgattgat agtcttagca
    32101 tatcatcttt taagttattt tagatatacg ggggcgcttt tgcaatcact attttgatta
    32161 gcatgtattt cccataattt tttcaacttt atgaaagata attaagaagc atctatctgg
    32221 tactaatgat ccagacagat gcttcttttt tatcaatatc ttattgttat ctcattaatt
    32281 atttttaacc atatcttcag ctgtgccaaa gattttacgt ttaattgctt cgccagttgg
    32341 tgtgcctgct agtccaccca atccagtttc acgtaatgat gcaggaaggt tacgaccaac
    32401 cttatccatt gcttcaataa cttcatcaac aggtattcta ctttcaatac ctgctaatgc
    32461 taaatctgct gaaattaaag cgttacccga accaattgca tttctcataa cacaaggaat
    32521 ttcaacaagt ccggctactg ggtcacaaac taaacctaat aaattactta tcgctaatgc
    32581 catagcgtgc ccggatgctt ctggtgatcc tccgaatata gctactgctg cagctgcggc
    32641 cattgcagat gctgaaccaa cttcagcttg gcagccacct gttgcaccag ctacacttgc
    32701 attgtttgct acgacacgcc caaacaatgc tgaagtgaat aagaaatcaa tcatttgctc
    32761 ttctgttaaa tcatgtgttt tttctaattt aaaaagtgca ccgggaatgg tacccgagga
    32821 accagctgtt ggcgttgcac aaataatacc catcgcagca ttgacttcat ttgttgcaat
    32881 ggcacctttg actgcatcaa tcatttcata tccagacaaa gcatgatgtg tttcattata
    32941 atcacgtagt ttagcagcgt catgaccagt gtagcccgtt acactttcaa cgccatcacc
    33001 tgtcgtccct ttgattactg cgtctcgcat gacatctaaa ttttgtttca tttgcgctcg
    33061 cacttcatca cgtgatttac cgcttaattc catttcttct ttaaccatga tatccgcaaa
    33121 tgacatatta ttttctacgg cataatctat agtctctcta attgaatcaa acatgtttat
    33181 tccccctcta atttatatag gaaacgttta cgtcactgta tttctcttta attgtattta
    33241 atgtcgattc tgagattgct ttatttaatg gtattacaac caagcattta tcttcatcta
    33301 tcttaataaa ttcatcttta cagtctaatt tcatatcgtt gatatcatta atgaaatgat
    33361 ttacttgtgc tttagtcata tttccgtcaa caactaaaat tggtaatcca tgatttaaat
    33421 ctacttctag tccatttata tgaatacctt taattttaat tgtaccacca ccgattgaaa
    33481 taccgataat ttcaatatag cgaccatcat tacgagatga tttaatataa gcacagtttg
    33541 gatgttgacc aatactatcg ccttcttctt cgatgatatc tattttaata ccatcatcag
    33601 ctgcaatttc taatgaagat ttaattcggt tatcaaatgt tgaatatccc attgctccac
    33661 ccacaatagc gacatctgta ccatgtcctt ggtgtgtttg agcaaatgat tcataataat
    33721 gtatttcaat atttttagga atatctccca atattgcgcg tgctgaattc ccaatcttta
    33781 ctgcaccagc cgtatgagaa cttgaagggc ccatcataac tggtccgata atatcgaaag
    33841 cactttgata atcatagctc tttgccataa ttaaacactc tccttaatat gattcttttt
    33901 gctcggcatt ttaaagttga tattcattaa attaaactta ttaattagtg ttccaataat
    33961 ataggctaag acaatgctga caataatcac tgttgcgatt gttacaattg atgtcactgc
    34021 attattaaag ccaaacaata cgatggcacc tgcaattggt gttgccatac ctttgacacc
    34081 tattactagt ccgctaaatg tcacgataca tgcgttgacg accccaatca gtgcatttgt
    34141 accatatagt tgtactggat attgcgctat taaatcaatt tgcgtcaatg gctcaataca
    34201 aactgcaaat gcttttgacg gtccaccaat gtttaatttt cggaataaaa taaggttaac
    34261 aaatgagcta cctgtacatg ttagtgctcc aatagccata ggaacacctg tcagtcctaa
    34321 taaacttgtt aataccattg aacttagcgg tgtcatacct gtaacaggaa tcactagtcc
    34381 taaaatgacc gctaatgcat atggattgtt atcacctacc gcagtgacag cactacctat
    34441 ttgttttaat gttgctagca caccaggtgt aatgattgat gcaagtccga aagcaattgc
    34501 tggtgcaaat aagatcacca caattaagtc caagccttct ggaactttct tttcaatcca
    34561 tttaattaaa aaagctacgc aataagctgc gatgaatgct ggtaataatt taaagtcatg
    34621 taatactaaa ccaacaataa ccgcaaatac tggtgcaacg cctaagttta agcacgttag
    34681 aatacctact gcgataccgc ttaaacttcc tgctaaatcc ccaatatctt gtagaaattt
    34741 aatatcaaat acgccaccaa tagcgtaact taagaatgct tgtggtagaa atgtcgcaca
    34801 agctgcaccg gataatgctt gtagtccttg tttaccgtac ggtgcatact ttaaaaatag
    34861 cgtcatgatc actaaaacca agactaatgt gcctacacct aacagaatat ccatttccca
    34921 aaaacctctc tctatgttta ttttattttc agaccataaa catcgtacac ccttaagaaa
    34981 acgttttcaa cttttatctg ttatcaaatc aaatatttaa gtgaaatatt tcatatttgt
    35041 gaaagatttt taaaatggat tgtttcaaaa actacttatg ttgtcattaa tatttactaa
    35101 ttaacttttt actctatatt tcaaacagtt gtgtgacagt tttttgataa cttttttaca
    35161 tctgaaagtg agtaatattt ctaaaaatct ttaatattta tacactttat ctttcgagct
    35221 atttattttt tgtttttgtg ctgtgtttat aaaaccgcac actatattca aaaataactt
    35281 attacacata tatttgcaat aagataatta aagtaggata ttatttttag ttttctgata
    35341 ggaatgatga tagtctatag gttgaatctt tacttttttt aaagctaaat ttacatcaac
    35401 ttaacaatgg ctggttatac tgaagatgaa aatatttagt ataacttagt ggaggcgata
    35461 aaggtgcaat tgagtcattc cgttaaagtt gcaatttcta tctatttagc acttatcttt
    35521 ataacgttca cttcttattt agtcattatt ttatatacga gtatgactgg acatgatgta
    35581 tcacatttcg tgttagatag tcagcattct catcatggat ctcttacgca aaaacatttg
    35641 agtcttcctg aaatctcatt taaatagttt atcctctgtg tttcaacatt catttcccat
    35701 atcgattcat ttatctatca tctagaccac tacatcttag atgatttttt tattttctca
    35761 tttcactctt tcttaaaagt cgatataatg aattaaatca ttatcataca ccgacatatt
    35821 ttatgttgtt ggtgttaagt tttaaagggg tgagatactt ggcgaataat cattcagctt
    35881 tgcgtttaaa aggaattata cttgccattg tcggtgcttg tttatgggga ttaggtggta
    35941 ctgtttctga tttcttgttc aaatataaga atattaatgt cgattggtac gtcactgctc
    36001 gacttgtagt cagtggtgtt ttcttactta ttatgtacaa aatgatgcaa cccaaacgtt
    36061 caatatttag cgtattccaa gatcgacgta tgttaggcaa attacttatc ttcagtatac
    36121 tgggcatgtt agttgtacaa tatgcttata tggcatctat taatacaggt aatgctgcga
    36181 ttgcaacatt actacaatac attgcgccag tttatattat tatttggttt gtcataagag
    36241 gcgttgcaaa actaacatta tttgatgtgc ttgctattat catgacacta ttaggaacat
    36301 ttttattatt aacgaatggt tcattttcta atttagtcgt caatcctgca agtttattct
    36361 ggggtatttt agctggtgta gcactcgctt tttacacaat ttatccttca gacctactta
    36421 accgcttcgg ttcgattcta attgtcgggt gggcaatgct tatttctggt gttgcgatga
    36481 atttacgcca tccaatttgg cacattgata tcactaaatg ggacatatca attatattat
    36541 ttttaatctt tggtattatc ggtggtaccg cactcgcatt ttatttcttt atcgacagtt
    36601 tacaatacat atcagcgaaa gaaacaacat tattcggaac tgttgaacct gtcgtagccg
    36661 ttatcgcaag cagtctatgg ttacatgtgg cattcaaacc atttcaaatc gtaggcatca
    36721 ttcttattat gattttaatt ttattactat cacttaaaag acaacctgaa gcattagatg
    36781 aataagaaaa ctctgataat cactttagca agtaactatt tttaacaacg tagctacctt
    36841 gtatgtgata tcagagtttt ttattttaat taataatatt tttcacttgg tataaaaagc
    36901 gtcggcgctc tggtatcgga aatactggat aaatatggaa ttggtaatat ccaggtataa
    36961 agtcatgttc gatacctttt gcactcaaca attgcgataa gttcaaagca tctgggtaca
    37021 gtacttcttt tgtgccaaca gttaatgtaa tacgacctaa accatctaag tcaccattaa
    37081 ttggtgatac tttgtagtta tctaaaggtg tgtcccctgc ccattgttca gctaagaaca
    37141 cactgccatc cacacctacc attgggtctt tctttaagta gtcaggaatt tcaggatgct
    37201 gcatcgttgc atctaaaact ggtgaaatta atacaatatg tcctggttgc acaatatgtt
    37261 tttcttttaa caattgagca aatgataaag caatttgacc gcccgcagag tcacccatta
    37321 caacgatttg tttagaatct gctacttgat tcaataaatc atggtataac ttttcaaaaa
    37381 gcacatacgt cgcttgataa tcttgatgcg gaatcttcgg atatactggc atgatgactt
    37441 tagcattgag tgtttctgca agttcatcaa taaattcgaa atgaattttg agtgggtctt
    37501 ggaaccatgc gcctccatgt gcgtataata caacgcgttg atgcttatct tgtttatcat
    37561 taacgttata aacggttgaa ccgtagtgct tatccactgt tactggcatc ttaaactgat
    37621 aattggtgcc ctcatattca cctgctgtct gtggcgccat tttttctaat gctttcatcg
    37681 cttcttcttt atacataaaa cgacgcttag ctctagataa tcgtatacct tgttctaaca
    37741 tataactttt cacactgcgt ttttctttaa ttctaatatg tgcgtatgct gctactaaaa
    37801 atccaaacgc aagtgtagac cattttttac gcatttgtcg tcactcctct ttgatgattt
    37861 ctactatagt tctactgtac catgctgatt cttattacta ccaatattta ctgggaaata
    37921 agttatgatg tctacataat cttagcaatg ctaatcattt gcgatattca tgctcatcga
    37981 catcgttatt cacactatca ttcatttgct taagatgatg ttcaaaacgt tgcatatcga
    38041 taaaacgccc ttgacgatgc atttcttttc cattcataaa aattaaatcc acaggtacag
    38101 tgaaaatatt taattctcca gcaatagctt caacttgact ttgattaatc acagctaatg
    38161 gcacattggg atatgattgc atcaagtctt caatttgtgg taaaacggca tgacacacgc
    38221 tacactgatc gcgcatgaca tgtacaactg ctaacggata ttgatgaata aattcacgga
    38281 atgcttcgac actatttaat tgcttaacca tttcgaacac cttcttactt tttatatttt
    38341 aaaatgaagt cattattttg ttgctaaaat gtcttgaaac acttgtggca cagaggttat
    38401 cttcttatca ctcaatctgt aaaaaccgcc tgtctgtgta ccaatacaat gcacgcaatg
    38461 tgcggacaca atttcaaact gaaacaccca tttcatcttg cttgctttaa ctaagtaaat
    38521 acgacctact ggtttgtcat gtattgtgac aggtacttta tactctgctt ccgttttcat
    38581 aagtataggt gaaatgcctt gattgatcat tgttgagtaa ttcatgtgct gattaataaa
    38641 cgctgttctc aaatcttcga accatctaat ataaacgata ttactaacga cacccatcgc
    38701 atcaatgtcg taaccattca cttcgatttc tttctctgca actaatagac cttctgttgt
    38761 cataatgaca aatctcctta tcttacaaat agatttaaaa tcatgttaat ttatttttat
    38821 tactttcatg ataaaaatac aagcaattga actttattac ggaaaatcaa acttttcaat
    38881 gagactatta atttggctag tcgcgaagat gcatttttct aaaatgtgac aaaaacataa
    38941 gcaatgtttt ctatatctaa cactaatatt taacttatta tcatcaacac acctgctata
    39001 catcattgcg cactaaaaag gcagtagctt cattttaagc tactgccttt tgtaacgtat
    39061 tctctttcaa ctcgctactt cgcatacgca ctacgaatga ctaaaagttc attcatttga
    39121 tatgctgttt catttttaat cattatttga ctgtcataat tagcttacct ggatcagcat
    39181 cttgtacatc ttcaatgaca agttctttat tttcaagatt tgtaataatc attggtgtaa
    39241 cgatgcttgg tgcgtgtgct ttcaagtatg ctaaattcac tttcattaat ggttggcctt
    39301 gtgttacttt ttcatcaacg ttaatcagac tttcgaatcc ttcaccattc agtttcactg
    39361 tatcgatacc aatatgaata agtacttcga cgccactttc agattctaat cctatcgcat
    39421 gtttcgtagg gaagattgtt ttcactgtac catcaaacgg tgctacaatt tcaccttttt
    39481 cagggataaa gccaatacca tcacccatca ttttaccagc gaatacttga tcaggtactt
    39541 ctgataatgg aatgatttga ccgacacctg gtgcatagat gtctgttgtt ccaagtgctt
    39601 ctacgtgaac tggttcatct gacatttctt cagtcactgt cgtttcactt ggtttcgtaa
    39661 tttcaccact cataatcttg gccatatcat gtttaatttg atctgatttt ggaccaaaga
    39721 tagcttgcat attgtttcca acttctaata cacctgatgc gcctaaagct ttaatacctg
    39781 ctacatctac ttttgattta tcaaccactt ctacgcgcag acgtgtaata catgcatcta
    39841 aatgtttaat gttttctttt ccacccattg catctaagac atcaaatggt aattttgcga
    39901 cactagagtt acgaatttca gtttcttcat cttcacgacc tggtgttttc aatttaaact
    39961 tacgaattgc aaagtcgaat aagaagtaat acacgatagc atatacaata ccgactggaa
    40021 taactaataa tgcgtgtgaa cgatcccagt ttaataaacc atataaaata taatctatga
    40081 aaccacctga gaatgtcata ccaattttaa cgcctaataa atgcattact aagaatgatg
    40141 taccagctaa taatacgtga attccataaa gtactggtgc tacaaataag aatgaaaatt
    40201 ctaatggctc agtgatacca gttaaaaatg cagttaatcc tgctgataac attaaaccac
    40261 ccacgacttt tttgcgttct ggtcgtgcat ttttataaat agcaaatgcc gccgctggta
    40321 aaccaaacat cataaatgga tatttaccag tagtaaatgc accagcagta aatggtacgc
    40381 catctttcaa ttgtgccatc caaatacgtt ggtcaccacg aactaattca cctgcgtgat
    40441 ttgtataact tccgaattca aaccagaacg gtgaatagaa aatatgatgt aaaccaaatg
    40501 gaattaatga gcgttcaata ataccgaata taaacgttgt taatgttaaa tttttattta
    40561 ataagaaatt cgataaacta tttaatccat cttgaattgg tggccacgca aagcttaaaa
    40621 gcacacctgt tgcgattgct acgaccgatg tcacaatcgg tacaaatcgt ttacctgcaa
    40681 agaatcctaa aaatggtggt agtgtaatat tataaaattt gttgtaacac catgcggcta
    40741 aagcacccat gataatacca ccaaacacac ccgtttgtaa cgttggaata cctaatacta
    40801 aagcatgtgc tggttctttc gctgcttgac ttaattcttt tgcccctttg gcatatgaga
    40861 aaatgtcatc aattgtaatg tgcaacactt tccccattgt tgcattcata attaagtaac
    40921 ctactagcgc tgctaatgct gcaacaccgt ctcctcctgc taatccaagt gctgtaccaa
    40981 ctgcaaataa taatggcaag ttatcaaata caacttgtcc tgctgcttcc atgaccgacg
    41041 aaatcattac aatgatatcg ttttttaacc atggtgcaat ttctactaat tgttcgttgt
    41101 gcattgcgtt accaaacgct aataaaatac cagctgctgg taaaatcgca acaggtaaca
    41161 ttaatgcttt accgatacgt tgcaattgtc caaacaattt cttaaacata taaacatccc
    41221 ctatctcaat ttccgcttcc atgtacaaaa aaagcaggca tgaacaaaca agactattct
    41281 catagtacgg ttgtttgctc atgcctgcat taccagtaac acgcaagtga tatgtaattc
    41341 atagctatta tacatatttg taaaagcgtt ttcaacaact ttttcacaat tttatcatca
    41401 attcagtacg atcatttgtg ataaataaac aaaacggcaa ttcccatttt gttgaaatag
    41461 aaattaccgt ttttatagtt caattcaatt gtgataacct ttcaatcagt tataagaaac
    41521 gttttgctgc aactgaaata ggtggaattt gatctaaatc taaatattta tcttcagtaa
    41581 tagatctaaa tgcccattta ccataaccaa gcgcttcttc atttacaatt ttacctggta
    41641 atggcgcagc attaggatca acatatacat ctacaatcgt tggtacatct tgtgctaatg
    41701 cctcttcgac tatagcatct acttcgctag cactcttaat tgtataacct ttaccacctg
    41761 ctgcctcagc aaattttgca tgatccatat cagaaaaatc aactgcatat tctaattcac
    41821 cagctgcttg ttgttcatat ttaataaatg ctaactgttt gttattaagt acaaatacag
    41881 ttaaaggtaa atcatattgt actgctgtag cgaagtcttg cattaccatt tggaatgcac
    41941 cgtcaccagc aatggcaatc gcttgtctat ttggatatgc aatttttgat gccatagctc
    42001 ctggaagacc gcaacccatt gtacctaacc aacttgaaat gatgaacttg ttgttcacac
    42061 caagatttaa ataacgtgta gaccaaactg ttgcagtacc aacatctgct gaaattactg
    42121 catcatcttt aataaatttg ttaattgatg ccattaaacg ttctggacgt aatggtttgc
    42181 tattattatt tttatcttgt tccatccatt tatcccaaac cgctttacgt tctaacgttt
    42241 tgtttaaaaa tggtctttcc gcaacatgtt taatattttc agttaactga tgcaatgcaa
    42301 ttttactgtc tccaacaatt cctacattaa tattaaaacg atgtccgata tttttaggat
    42361 ttgtgtcgat ttggattgct ttaatatttt tcttaggtaa gtaatccaca tatggatagt
    42421 ttgtaccaac cataattaat aaatccgctt cctgcattgt ttgataagat gttttggtac
    42481 caattttacc taagttaccg atactatatg gatgatcatc cggcaagatt gttttagctg
    42541 gtaatgaatg aatgacagga attttagcca tttcaataaa ttcacgtagc tcatctttcg
    42601 catgttttgc acctacacca attaacatga caggcttttt acttttatta attagtttaa
    42661 ccgctttttt gatgtcttta tattttggtg atacaactgt tggtcttgat gtatctactg
    42721 gtttattcgt tgtatcttta attttttcag ttaataagtc gttaggacaa ataacaacag
    42781 cgacaccttt ttgttcatat gccgtacgaa ttgcttcgtt aacgatttca aacacattgt
    42841 cacctttttc aatttggtga ttataaacgg ctacatcttc acataatttt tgtaaatttg
    42901 tttcttgaaa tgctttcgtt ccaagtgctg tactattcgt ttgtccagat aatattaatt
    42961 gcggtacatt atccattttg gcatcgtaca taccatttaa taaatgaatt aaaccagggc
    43021 caccgatact taatgccaca ccgattttac cagttaattt tgtgtaacca gcagccgcta
    43081 agcttgctac ttcttcatga cgtacatgat aaaatttaaa ttgatctctc actgtacgta
    43141 aactatcgac aactgcgtcg attgagtctc ctggaatacc atacaagtga tctatatccc
    43201 atgcttgtaa tgctttaact aatgcttcat ttgcttttat ttttgccatt attactaata
    43261 gcctcccttt cttagtgtct atcattttaa atatctaaat taatagaata ataaaattag
    43321 aacaggtatt aacactgaac taataactgc agttaaaatc atcccaattg aactaaatgc
    43381 accggattca atatccattt ctagtgcttt agctgtgcca aatgcatgtg acgcattccc
    43441 atacgttaaa cctttggcga tagaagattc aaatcttcca aatcttaata acatcgaacc
    43501 taaaatacta ccgattaaac ccgttgtgat aataaaaagt acggtcatcg tatctgtacc
    43561 acctagttca tgtgacactt cgatacctac tgcggctgtt atagatcggg gcaataacgt
    43621 tacaatgacg tctttagaat agccaaatgc tttaagtgtt aagaacacta acatgaaatt
    43681 cagcatgacg ccagttaata cacttgcaaa aatgatagag acattgtctt taattttctc
    43741 tctattttta taaagtgggt acgctaaaca tacgaccgtt gcgtttaaaa tatggttgat
    43801 ccaactgcca cctttcatat acccgttata actaattcca aagataagta agacaaaaat
    43861 aattcctaaa gatgcaatta atgctggatt caaaaatggg ttcggatatt tttgttgtaa
    43921 ccttttagcg aaataatata aaacgacagt caacaaaatc attaataagg cttgcacgta
    43981 atcattcata agcgtctaca cctttacgat gtttatgttt aacagacatt ttttcagcaa
    44041 tataacctga agataatgca acgatacatg ttcctataat aatgactgcg aaaaagagta
    44101 tataatttag cgtaatttcg gaagcaacat ccataatacc tacaactgac ggtatgaaga
    44161 aaaagaccat cgtctttaat aaaaagtttg caccgtcttc tacccaagtt agcggtacaa
    44221 tcttaaattg taatagtaaa taaaataaaa atagaccaac aatactgccg gctaagggaa
    44281 gatgaaaaat cttttgaatt tctgtgccaa tataagtaat cacaatgatg attcctagtt
    44341 gtagtagtag tttgattatt aattggactt tgtgcatggc gccatccctt tctaaatatg
    44401 tctaaaatgt tacaataact attataaaga tggcgtgcac aatataaaaa tactcttttt
    44461 ttatagtttg tattactatt ttctatggaa acgctctctc aatttcactt cattttcaca
    44521 aaaaaacact catcatttca atgacccacg taatgatgcg ccttaaataa tgagtgcttt
    44581 attaatatgt tagcctaaac gatctttcaa aaattctatc catttcgttg tggcatgact
    44641 taattgttta tccttcttcc aaacaacacc taattcccaa tgtacatgcg catcttcaat
    44701 gcgtagcagc ttcacatctc catttagttg ctctgaaatt gatgttggta aaatactaat
    44761 acctaattca ttcgtaacta aatcttctat aacatgccat tgtgaaattt gcgctacagt
    44821 attcggaaca aagccaacgt ttttagcatt ttcaataatt ttatcattca agtaaaagtc
    44881 tttattaaat aaaatgaagt cttcacctgc taaatcttcg agtttaacag tttcatattt
    44941 tgcgagtcga tgctctctgc tcacgataag tcgcaaatct tccttatcta gggtagtata
    45001 atcgaaaata tgatgatcga ctggcaaagt ggtcacgcct atatctactt catcattgat
    45061 aatttgctgc tcaatcgttt tgccgccatt ttctattaaa ttatatgtaa catttggata
    45121 ttgctgatgg aatgcaccaa gaatattgat aagaatcttc atattcatga ctgccgacat
    45181 gcccatgttt atatgccctg tttccagtcc attcaagcgt tccatttcag atggtaaata
    45241 atcatacagt gcaacaattt ctttactttt ctcataaaaa atttgacctg catcggtaag
    45301 tattaaatgt cttttacttc tatcaaataa gggcgtgccc atttcatttt caatatcttt
    45361 aattgcttta ctaattgtag gttgtgcaat atataatgat ttggaggcat tagtcatgcc
    45421 tccttgctta acgacttcaa taaaatattt catatgtttg atatccacta acatcatcct
    45481 aactatttca acacgtttat ttcattatac acaacttctt aaacattcaa taaatttaga
    45541 tttataaaat tgctttataa aaagttttat gtaaaataca cattctttta tggtattata
    45601 ttaatggctc aagtttgtta ttcgaggtga ggtattgagc ttttacgaat ttatgcaaag
    45661 ttttcttggt gatgacacac cattaggtga attggttgat tggattaatc aagatagcaa
    45721 tttccctaga gaagtgaaga gccatagtga aatattgtca tattttcgaa caaatccatg
    45781 tcctgaaagc atctcagtac ctgtaattaa acgggcacta tcagttttca accaattcac
    45841 aaatgtacaa tgatacatga atacatggag tcacatcatc tcatgttagc gctctgattg
    45901 cagggcgcta tttttaatgt tatcgctaca tttagtatat tgtgattgct attttctttc
    45961 agttatagaa ccacgtacct tttcttttaa atcattttat attttcccac taatatccgc
    46021 tgttaatcaa ttctgacatc cttgtatcac tatgacaatt aattgttaaa tacatgaatt
    46081 tctacatttt atgaaaaaat ccatttttat tacaattcaa cactttatat gacaacttca
    46141 ttacagttac ttttattgtt gattgcttgc attgttttct aaaaaaattt tgttatcata
    46201 attaacgttg aataaagaaa aaaattaact tgggagataa aaatggaata taaaaagata
    46261 ctaattcgtt tattaattgc ttttgcagta cttttctcag cagatttcac ttatcaatcc
    46321 gtcgaacaaa cgcatcaatc gcatgccgca gttaattatt atagtaaaaa ccaatgtaca
    46381 tggtgggcat ttaaa
//
LOCUS       DAPDIM010000015        43181 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000015 DAPDIM010000000
VERSION     DAPDIM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 43181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43181
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.015"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(82..1101)
                     /locus_tag="RFE25_000900"
     CDS             complement(82..1101)
                     /locus_tag="RFE25_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDU2815989.1"
                     /translation="MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIV
                     LGNVVEADEFYHSNPFKFGASIGRYSGRIDNAKFKLKGKEYQLEKNNGEHHLHGGCHG
                     LDNKLFDYEIRNEIAQIKVIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVA
                     SEDTLFSPMNHVYFNLNRDNNVVDNHRISSNQLDMYVLDERNIVTGDILDLHEVFEDN
                     KIKLSDIFTSQHAQLSQQMTRFGGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFT
                     FNQPDEWDSPFNIYKPHSGFTLETQFLPNDINLYGEKAPSILKAGEVFNSKTSFRIEE
                     KVEND"
     gene            complement(1131..1457)
                     /locus_tag="RFE25_000901"
     CDS             complement(1131..1457)
                     /locus_tag="RFE25_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HDU2815990.1"
                     /translation="MLYPIFIFILAGLCEIGGGYLIWLWLREGQSSLVGLIGGAILML
                     YGVIATFQSFPSFGRVYAAYGGVFIIMSLIFAMVVDKQMPDKYDVIGAIICIVGVLVM
                     LLPSRA"
     gene            complement(1506..1691)
                     /locus_tag="RFE25_000902"
     CDS             complement(1506..1691)
                     /locus_tag="RFE25_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2815991.1"
                     /translation="MYLKNKIDESDTHLSYKMMMKACYSYFFIFSYRIMSKKVYNMNV
                     KTNFLKWECEVRRNVNK"
     gene            complement(1675..2907)
                     /locus_tag="RFE25_000903"
     CDS             complement(1675..2907)
                     /locus_tag="RFE25_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2815992.1"
                     /translation="MHKFWATFTLTYIKKIKAKSFVIFMIIIAALMIGLSNIDKIINM
                     FDDGPDKIGVAAPNEQIYKVFKQQANTFHSDAKFTKVSIEDAEKEVKKHKLDKAYIIK
                     VNQNRTLQGTIISEKRVSHEDSQKVQALLTAIQTNMVAGELNINKEDLQKLQAQSKVD
                     NKVISNDEVDKVSEGQKIFNYALAYGIIFLMFFIVLNYASQIAMEIASEKTSRVIEMI
                     ITSISPIQHIFAKILGVIAVAVTQIILIVLMAVICIFAFDLKDLLQGFNVEMNQLSWQ
                     IIIVGIISSIVGIMAYVLLAAILGSLTSRIEDLNQSLMPLTLLGMIAFYIAIFTINNP
                     DGQLALITSYIPFLAPFQLVVRAQTSGLQIYEVILSSLISIVMVAVLIWIAIKTYKDS
                     VLTFERGLFNSMKRVFKK"
     gene            complement(2900..3799)
                     /locus_tag="RFE25_000904"
     CDS             complement(2900..3799)
                     /locus_tag="RFE25_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2815993.1"
                     /translation="MGLVIEHVTKRFGKMTAVNDISLELESGKMLGFLGRNGAGKTTT
                     FRMILGLSEPTEGHITYNGKKLDKTMYNRIGYLPEERGLHGKLTVEEELKYLATLKGM
                     SKTEIQQQISYWLERFDITENRKKRIDSLSKGNQQKIQLLASMLHKPELLILDEPFSG
                     LDPVNVELLKEAVKDLNDWGSTIVYSSHRMEHVEELCDDVCILDKGQLVVSGDINHVR
                     ASNGNKKVVIESETTLPDLTNIRGIIHSENMKQGLQLTIENEDVAKDIYQVVAHQGYV
                     KRFQVVEPSLQDIFIEKVGGKDA"
     gene            complement(4030..4650)
                     /locus_tag="RFE25_000905"
     CDS             complement(4030..4650)
                     /locus_tag="RFE25_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDU2815994.1"
                     /translation="MEQLPQVGFMKSFVLFWKNYVNFKGRSRRSEYWYMALWHLILMV
                     PAVCVLIINLFLVFISIAADNETLIVMSILMIILTSVYTFVYSLATFIPNLALCVRRF
                     HDISRTMLFPMIMTVFSIIFYIVLQIIDSYYDSDFTLMPMGLNILLVLLYFVYLGLTI
                     VMIVFLCFDSKPANKYGESPKYPSTIKNQPVTSETPKTPEETDNQL"
     gene            5049..5657
                     /locus_tag="RFE25_000906"
     CDS             5049..5657
                     /locus_tag="RFE25_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDU2815995.1"
                     /translation="MDFVNNDTRQIAKNLLGVKVIYQDTTQTYTGYIVETEAYLGLND
                     RAAHGYGGKITPKVTSLYKRGGTIYAHVMHTHLLINFVTKSEGIPEGVLIRAIEPEEG
                     LSAMFRNRGKKGYEVTNGPGKWTKAFNIPRAIDGATLNDCRLSIDTKNRKYPKDIIAS
                     PRIGIPNKGDWTHKSLRYTVKGNPFVSRMRKSDCMFPEDTWK"
     gene            5990..7198
                     /gene="gltS"
                     /locus_tag="RFE25_000907"
     CDS             5990..7198
                     /gene="gltS"
                     /locus_tag="RFE25_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDU2815996.1"
                     /translation="MIELNAITTLCLACILYLLGTAIVNHVNFLKRICIPAPVIGGLI
                     FAILVAALDSFGMVKIKLDASFIQDFFMLAFFTTIGLGASLKLFKLGGKVLLLYFMFC
                     AIISVIQNIVGVSLAKVLNIKPLLGLTAGSMSMEGGHGNAAAYGKTIQDLGIDSALTA
                     ALAAATLGLVFGGLIGGPVVKYLIKRYNLKPQHSDDTFKDYSQVAYNEHLHSKFNATE
                     VFFIQFTIVVFCMAVGSYFSHLFTAQTGINVPIYVGSLFVAVIVRNISESFNFNIVDL
                     KITNQIGDVALGIFLSLALMSIQLIEIYKLAIPLIIIVLVQVVVMILFAVLILFRGLG
                     KDYDAAVMVGGFIGHGLGATPNAMANLDVITKKYGNSPKAYLVVPIVGAFLIDLIGVI
                     VIMGFIQWFS"
     gene            complement(7246..8295)
                     /locus_tag="RFE25_000908"
     CDS             complement(7246..8295)
                     /locus_tag="RFE25_000908"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDU2815997.1"
                     /translation="MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVN
                     DIDLTSQTPDLTMAYPIYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRN
                     PRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPE
                     GNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNF
                     VDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALG
                     AKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPE
                     IMSWIEQRSLNIHRG"
     gene            complement(8326..9273)
                     /gene="corA"
                     /locus_tag="RFE25_000909"
     CDS             complement(8326..9273)
                     /gene="corA"
                     /locus_tag="RFE25_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HDU2815998.1"
                     /translation="MALKIRYQTTYEPFKVVDDIKEIPKDATIVWYDFDEPNEQENEW
                     FKAHFNFNDLEVDDAINGMPRAKYKSYKDYQYLVFHSIMGSNYSPIALNIFIQDNVLV
                     TYHHQTLESLNKVVYKYMNTLDAELDCADVVILILDMMVDKYFNFVYALEDSVYHFED
                     RHVDDRFNKMVMDSVFKLRSDLIKVKRVLFPMQELIDTMKQNGDLIIDNKHSLYIQHI
                     DDHLIKQRNIIRTAQEMTNEIRENFESYTSFRMNSIMQVLTLVSVIFSPLTFIAGIYG
                     MNFVNMPALHLHYGYYICLAVMFVIAVVLIIFFRRKKWF"
     gene            9370..9861
                     /locus_tag="RFE25_000910"
     CDS             9370..9861
                     /locus_tag="RFE25_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HDU2815999.1"
                     /translation="MVIIKQLFTHTQTVTSEFIDHNNHMHDANYNIIFSDVVNRFNYS
                     HGLSLKERENLAYTLFTLEEHTTYLSELSLGDVFTVTLYIYDYDYKRLHLFLTLTKED
                     GTLASTNEVMMMGINQHTRRSDAFPESFSTQIAHYYKNQPTITWPEQLGHKIAIPHKG
                     ALK"
     gene            9858..10277
                     /locus_tag="RFE25_000911"
     CDS             9858..10277
                     /locus_tag="RFE25_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816000.1"
                     /translation="MTDALQQKIHIELLDLLDDVKFELTELNAQKGLYINGPANQLLK
                     RGVHMAYVQGQKQAIDNIMTIVEQQLEDQHFLEDYDKFQNEVTHRNYDKTANFAELSD
                     IPRQFDNFLDQFYQIKGQYFIITHINTLIGDFHSEAH"
     gene            complement(10385..11305)
                     /locus_tag="RFE25_000912"
     CDS             complement(10385..11305)
                     /locus_tag="RFE25_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2816001.1"
                     /translation="MIRNRVMNSVVNKYLLHNRSIMFKNDQDVERFFYKREIENRKKH
                     KQPSTLNVKANLEKLSLDDMQVFRFNFRHQIDKKILYIHGGFNALQPSPFHWRLLDKI
                     TLSTLYEVVLPIYPKTPEFHIDDTFQAIQRVYDQLVSEVGHQNVVVMGDGSGGALALS
                     FVQSLLDNQQPLPNKLYLISPILDATLSNKDISDALIEQDAVLSQFGVNEIMKKWANG
                     LPLTDKRISPINGTIEGLPPVYMFGGGREMTHPDMKLFEQMMLQHHQYIEFYDYPKMV
                     HDFPIYPIRQSHKAIKQIAKSIDEDVTQNN"
     gene            11513..12151
                     /locus_tag="RFE25_000913"
     CDS             11513..12151
                     /locus_tag="RFE25_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816002.1"
                     /translation="MTNPNQRLEPFDETFQQPNIHRGKRYGKKKRSLVSMIIQIIVVI
                     LTAIAGYSMWKQPIFNIVFTKESVDFDGIKNFNETIGKMHQLNINLGNINDLQQGIDR
                     LILVFNGFFILCIVSLVITILTIVFNRTVLKVVNILVLTIMLVITLYFSYIIKTLAQE
                     IADALKKYYLNVPPDQVITEADAIHNGIILLGCSIGLLVISLFFRNRMPRLK"
     gene            complement(12397..14328)
                     /locus_tag="RFE25_000914"
     CDS             complement(12397..14328)
                     /locus_tag="RFE25_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="HDU2816003.1"
                     /translation="MTTTFIISYIILALIIVGVINLFLIRSRKKGKRQQKEQQFTTRQ
                     SNQSKFKASDLDKTTDQSTQRMTHEELRVDNQDDHSQVSLNGYTKGSEKDQEAFTNNN
                     GEEAVAAKNPESEEYKVNEKIKKEHKNFIFGEGVSRGKILAALLFGMFIAILNQTLLN
                     VALPKINTEFNISASTGQWLMTGFMLVNGILIPITAYLFNKYSYRKLFLVALVLFTIG
                     SLICAISMNFPIMMVGRVLQAIGAGVLMPLGSIVIITIYPPEKRGAAMGTMGIAMILA
                     PAIGPTLSGYIVQNYHWNVMFYGMFIIGIIAILVGFVWFKLYQYTTNPKADIPGIIFS
                     TIGFGALLYGFSEAGNKGWGSVEIETMFAIGIIFIILFVIRELRMKSPMLNLEVLKFP
                     TFTLTTIINMVVMLSLYGGMILLPIYLQNLRGFSALDSGLLLLPGSLIMGLLGPFAGK
                     LLDTIGLKPLAIFGIAVMTYATWELTKLNMDTPYMTIMGIYVLRSFGMAFIMMPMVTA
                     AINALPGRLASHGNAFLNTMRQLAGSIGTAILVTVMTTQTTQHLSAFGEELDKTNPVV
                     QDHMRELASQYGGQEGAMKVLLQFVNKLATVEGINDAFIVATIFSIIALILCLFLQSN
                     KKAKATAQKLEASSNNNHE"
     gene            complement(14341..14988)
                     /locus_tag="RFE25_000915"
     CDS             complement(14341..14988)
                     /locus_tag="RFE25_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDU2816004.1"
                     /translation="MKKMILINVITVVVLLAIGIAGFYFWNKTTSYVTTDNAKVNGDQ
                     IKIASPASGQIKSLNVKQGDKLDKGDKVATVTVQGQDGETKDMDLKMPQKGTIAKLDG
                     MEGSMVQAGNPIAYAYNLDDLYVTANIDEKDIKDVEVGKDVDVTIDGQKASIKGKVDS
                     IGKATAASFSLMPSSNSDGNYTKVSQVIPVKITLESEPSKQVVPGMNAEVKIHKN"
     gene            15109..15663
                     /locus_tag="RFE25_000916"
     CDS             15109..15663
                     /locus_tag="RFE25_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001661235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDU2816005.1"
                     /translation="MKRQAKIEIQNALVDLMAEYPFQEISTKMICAYCNINRSTFYDY
                     YKDKFDLLDTINSKHKEKFQFLLSALHHNFENIKQDKLKLYKFFIIIAKYIKHNEQFF
                     KDILVTYPMKTLFIDYINLARDYYQQIMNDYSTTVTNKQLYVTYIIGGQAGVFINWLS
                     NGCNESPEEVADILLANTIKLQIQ"
     gene            complement(15890..17098)
                     /locus_tag="RFE25_000917"
     CDS             complement(15890..17098)
                     /locus_tag="RFE25_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HDU2816006.1"
                     /translation="MNDLTHFNKRSPIFIIILGSLTAIGALSIDMFLPGLPDIRHDFQ
                     TTTSNAQLTLSMFMIGLAFGNLFAGPISDSTGRRKPLIIAMIIFTLASLGIVFVHNIW
                     LMVALRFLQGVTGGAAAVISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGII
                     LNYSVWRMVFVILTIFGFVMVIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPR
                     FVLPMLIQGMTFVILFTYISASPFIIQKIYGMTAIQFSWMFAGIGITLIISSQLTGYL
                     VDFIDSQKLMRGMTMIQIIGVILVTIVLLNHWNFWILAIGFIILIAPVTGVATIGFTI
                     AMDESSSGRGSSSSLLGLVQFLFGGVASPLVGVKGEDNPIPYIIIIIATAVILIILQI
                     YNMKVFKTNR"
     gene            complement(17208..17336)
                     /locus_tag="RFE25_000918"
     CDS             complement(17208..17336)
                     /locus_tag="RFE25_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816007.1"
                     /translation="MEYKQHPFKVFTISVNYFEGIVFCEKIYGVLRFISFYTFYKL"
     gene            complement(17367..18749)
                     /locus_tag="RFE25_000919"
     CDS             complement(17367..18749)
                     /locus_tag="RFE25_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDU2816008.1"
                     /translation="MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNN
                     IKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTK
                     DNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRV
                     SKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFIP
                     GTYRIPAMKSTENGDFAGYLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSK
                     KVTINDREMAFSSSKTYGPYPQNKDITISASGKAKGKTFTTQTKTIKASDLKYNTEIT
                     LNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSS
                     FYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQD
                     RLQLIKTSEK"
     gene            complement(18989..19444)
                     /locus_tag="RFE25_000920"
     CDS             complement(18989..19444)
                     /locus_tag="RFE25_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDU2816009.1"
                     /translation="MVKHLQDHIQFLEQFINNVNALTAKMLKDLQNEYEISLEQSNVL
                     GMLNKEPLTISEITQRQGVNKAAVSRRIKKLIDAKLVKLDKPNLNIDQRLKFITLTDK
                     GRAYLKERNAIMTDIAQDITNDLNSEDIENVRQVLEVINHRIKTYSNHK"
     gene            19639..20607
                     /locus_tag="RFE25_000921"
     CDS             19639..20607
                     /locus_tag="RFE25_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDU2816010.1"
                     /translation="MLLNLLLIFILIVICPLIFNYTLTLNLTCYILVVISIFLSLIYS
                     IMTYTFPWSMFVTFIIISIIMLFKHRYLFSHTSSRLFIKKLLSFSYKFVLYTSALLFI
                     STIQSPIVKGLSMWLAILCLSLLLTFICYLVWTVSYRHRSYNKEVDIIIVLGAGIFTE
                     FVTPMLAARLDRALDIYQQQASATKIIVSGGQGPDEPISEALAMQRYLIAHGVDKTDI
                     LMESHSINTYTNFLYSKQIINNLYHEAVKIVCVTSQFHVLRALRLAQKLGLSIDGVGS
                     HTPYHFFLHVLIKDYLGVMYQYRLLLTLYCSSSWFICLYAAFIYNS"
     gene            complement(20838..21503)
                     /locus_tag="RFE25_000922"
     CDS             complement(20838..21503)
                     /locus_tag="RFE25_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816011.1"
                     /translation="MALVVKDIVKNFGEGLSETKVLKGINFEVEQGEFVILNGASGSG
                     KTTLLTILGGLLSQTSGTVLYNDAPLFDKQHRPSDLRLEDIGFIFQSSHLVPYLKVIE
                     QLTLVGQEAGMTKQQSSTRAIQLLKNIGLEDRLNVYPHQLSGGEKQRVAIMRAFMNNP
                     KIILADEPTASLDADRATKVVEMIRQQIKEQQMIGIMITHDRRLFEYADRVIELEDGK
                     ITD"
     gene            complement(21503..22558)
                     /locus_tag="RFE25_000923"
     CDS             complement(21503..22558)
                     /locus_tag="RFE25_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2816012.1"
                     /translation="MKLAIKEIMFYKFRYILITLIILLLSIMVLFISGLAQGLGRENI
                     SLFEHFDNDEYVVQKMKEPQIEKSQLSDTQQNQIKKVIHQEPYKMNIQTLKLSNKEQD
                     VITMNDVKQQRIQLKKGDYPKNAHEVAINDKLAADNIRVGDRLHFKNNSTSYRVSGIL
                     NDTMYAHSSIVLLNDNGFNALNKVNTAFYPVKNLTQQQRDELNKINDVQVVSEKDLTG
                     NIASYQAEQAPLNMMIVSLFAITAIVLSAFFYVMTIQKISQIGILKAIGIKTRHLLSA
                     LVLQILTLTIIGVGIAVIIIVGLSFMMPVTMPFYLTTQNILLMVGIFILVAILGASLS
                     FIKLFKVDPIEAIGGAE"
     gene            22694..23368
                     /gene="hssR"
                     /locus_tag="RFE25_000924"
     CDS             22694..23368
                     /gene="hssR"
                     /locus_tag="RFE25_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding heme response regulator HssR"
                     /protein_id="HDU2816013.1"
                     /translation="MVQCLVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQ
                     RVDIAVVDIMMDGMDGFQLCNTLKNDYDIPVIMLTARDALSDKERAFISGTDDYVTKP
                     FEVKELIFRIRAVLRRYNINSNSEMTIGNLTLNQSYLELQVSNKTMTLPNKEFQLLFM
                     LAARPKQIFTREQIIEKIWGYDYEGDERTVDVHIKRLRQRLKKLNATLTIETVRGQGY
                     KVENHV"
     gene            23361..24734
                     /gene="hssS"
                     /locus_tag="RFE25_000925"
     CDS             23361..24734
                     /gene="hssS"
                     /locus_tag="RFE25_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme sensor histidine kinase HssS"
                     /protein_id="HDU2816014.1"
                     /translation="MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKI
                     MKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTVDQKGHKTFYGEPFREDTLSQNA
                     INNVLNNKDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFS
                     EFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDE
                     IGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQQ
                     YINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVDQLIKDIIRHEQFAADEKS
                     LIILADLESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISND
                     GSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTI
                     TLPNNSH"
     gene            24897..25340
                     /locus_tag="RFE25_000926"
     CDS             24897..25340
                     /locus_tag="RFE25_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2816015.1"
                     /translation="MMKLNLFINANETESYIDIHAPKMNDHVQSIINAVNDLDKSHTL
                     VGYIDKEIHIINVSDVITFQVINKNVTAITSNQKFKLKLRLYELEKQLPQHFIRISKS
                     EIVNKYYIEKLLLEPNGLIRMYLKDAHYTYSSRRYLKSIKERLSI"
     gene            25337..25792
                     /locus_tag="RFE25_000927"
     CDS             25337..25792
                     /locus_tag="RFE25_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HDU2816016.1"
                     /translation="MKNLKNSLFISLIIGLSLSLFFSMLFADGKYYPLNPQSTIGILY
                     YNHFTETTVMLISIILWLLIGVVFFLGDFIFKYTDWSITKATIMHFITTYVGFLPLAM
                     LAGWFPLTVHYLIIFTIIFIVIYVLIWIIQFFKNKNYVDTINEQLKQLK"
     gene            complement(25858..27336)
                     /gene="mqo"
                     /locus_tag="RFE25_000928"
     CDS             complement(25858..27336)
                     /gene="mqo"
                     /locus_tag="RFE25_000928"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDU2816017.1"
                     /translation="MTTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQP
                     GEESSNVWNNAGTGHSALCELNYTKEGKDGTVDCSKAIKINEQYQISKQFWAYLVKTG
                     QLDNPDRFIQAVPHMSFVIGEDNVAFIKSRVATLKKSVLFEKMKLSQDEEEMKSWVPL
                     MIEGRKSDEPIALTYDETGTDVNFGALTAKLFENLEQRGVGIQYKQNVLDIKKQKSGA
                     WLVKVKDLETNETTTYESDFVFIGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTN
                     QEVIDRHHAKVYGKAAVGAPPMSVPHLDTRFVDGKRSLLFGPFAGFSPKFLKTGSHMD
                     LIKSVKPNNIVTMLSAGIKEMSLTKYLVSQLMLSNDERMDDLRVFFPNAKNEDWEVIT
                     AGQRVQVIKDTEDSKGNLQFGTEVITSDDGTLAALLGASPGASTAVDIMFDVLQRCYR
                     DEFKGWEPKIKEMVPSFGYRLTDHEDLYHKINEEVTKYLQVK"
     gene            complement(27717..29315)
                     /locus_tag="RFE25_000929"
     CDS             complement(27717..29315)
                     /locus_tag="RFE25_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDU2816018.1"
                     /translation="MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITT
                     LVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQ
                     DSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLV
                     ANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGF
                     RGVKETLPAILVVSITYTLTQGLLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIY
                     RVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKF
                     NLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAVRLFGVTFKEL
                     WLPVLTICFILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNN
                     NSLFAPIQASVAQQIGTSGSLLVSANTVGGVAAKLISPQSIAIATAAVKQVGKESELL
                     KMTLKYSVCLLIFICIWTFILSLL"
     gene            29632..31305
                     /locus_tag="RFE25_000930"
     CDS             29632..31305
                     /locus_tag="RFE25_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDU2816019.1"
                     /translation="MIKQINVSNMQKFESQLMKAQSEGYTHVVPYANEIMIYQSMLDA
                     VQLYPKSIVVDYTVDGQYKNDCHYFGQSSINIADWAQNNNYYPNLIYAIQQTLDLIHY
                     YSVETIFDLALLTLLKGDLSIDGHVVFDFKAPIATSASIWETIKTIEDFDMMSQFYLN
                     KMAYIDHHPIPFRNLFIEDSEQLNSPDNWLYSTKFMLPKWLYKIAKQRADNKQLQNFG
                     LYTKQPNVLKDHIVFIGDHHQYIGNSKYLFTYFVKHNPMTACYFVTDDRRGPHFISPK
                     SEKADELINSARVVIVENDIPETLQPNGTLIQLHQGTPIMQLFLDSKEPIKNIETPFY
                     RAKRYNRWLQFDYVIHSADDISHFYQTAFPSHQANVLAYGNPKHQYLLQKRNESTTQQ
                     QYKKSFKINDQKPVLLYAPIGLVSAQQLPLSDALFKAYHVVVQGVDEAILPEEALVAP
                     KYLSAQDLILMSDVVITDYSNIIFDAMAIDKTVALYTPNHSQYIESQGVNEDIWRHLS
                     KIWYTDRQLLINNLISQAIPVIKYPQIQHKEQPLESISQLILSKMTSNQ"
     gene            complement(31459..32073)
                     /locus_tag="RFE25_000931"
     CDS             complement(31459..32073)
                     /locus_tag="RFE25_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816020.1"
                     /translation="MKRLVTGLLALSLFLAACGQDSDQQKDSNKEKDDKAKTEQQDKK
                     TNDSSKDKKDNKDDSKDVNKDNKDNSANDNQQQSNSNATNNDQNQTNNNQSSNNQKSS
                     YVAPYYGQNAAPVARQIYPFNGNKTQALQQLPNFQTALNAANNEANKFGSNNKVYNDY
                     SIEEHNGNYKYVFSFKDPNANGKYSIVTVDYTGQAMVTDPNYQQ"
     gene            complement(32387..32902)
                     /locus_tag="RFE25_000932"
     CDS             complement(32387..32902)
                     /locus_tag="RFE25_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2816021.1"
                     /translation="MAGIIKEISEQNASELVELATRTFYDTFGSYYDDKDFDQFFKDN
                     YTVEKFTQEINHVDSFHYFYQEDGANVGYIKMNINSAQTEEMGETYLEVQRIYFLKDF
                     QGGGRGSQLIELAEKIAQEHNKHKIWLGVWEHNPRAQAFYKRHGFKVVGEHHFQTGDV
                     TDTDLIMEKEL"
     gene            33093..34097
                     /locus_tag="RFE25_000933"
     CDS             33093..34097
                     /locus_tag="RFE25_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDU2816022.1"
                     /translation="MIETFKAFVIDKDESGKVTPTFKQLSPTDLPKGDVLIKVHYSGI
                     NYKDALATQDHNAVVKSYPMIPGIDLAGTIVESEAPGFEKGEQVIVTSYDLGVSHYGG
                     FSEYARVKSEWIIKLPDTLTLEESMIYGTAGYTAGLAIERLEKVGMNIEDGPVLVRGA
                     SGGVGTLAVLMLNELGYKVIASTGKQDVSDQLLELGAKEVIDRLPVEDDHKKPLASST
                     WQACVDPVGGEGINYVTKRLNHSGSIAVIGMTAGNTYTNSVFPHILRGVNILGIDSVF
                     TAMKLRQRVWRRLAKDLKPENLHEIKQVITFDELPEQLNKVINHENKGRIVIDFGVDK
                     "
     gene            complement(34143..34544)
                     /locus_tag="RFE25_000934"
     CDS             complement(34143..34544)
                     /locus_tag="RFE25_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2816023.1"
                     /translation="MVKVTYDIPTCEDYCALRINAGMSPKTREAAEKGLPNALFTVTL
                     YDKDRLIGMGRVIGDGGTVFQIVDIAVSKSYQGQDYGSLIMEHIMKYIKNVSVESAYV
                     SLIADYPADKLYAKFGFMPTEPDSGGMYIKY"
     gene            complement(34580..35614)
                     /locus_tag="RFE25_000935"
     CDS             complement(34580..35614)
                     /locus_tag="RFE25_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDU2816024.1"
                     /translation="MKDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYP
                     EKIIWDIGGIAPKPCHEILKDTIKQGLYFKPEVHLNERVVDIRKKAERHFEVETEAGE
                     IYTSKAVIIAIGAGIINPKQLDVKGVERYQLTNLHYVVQSYRRFKDKDVLISGGGNTA
                     LDWAHDIAKIAKSVTVVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHI
                     SEVVLEHVESGDRHTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGFGNTTTS
                     IPGIYACGDIVYHDAKSHLIASAFSDGANAANLAKTYIQPDANAEGYVSSHHEVFKEA
                     NKTIVNKHLY"
     gene            complement(35625..35741)
                     /locus_tag="RFE25_000936"
     CDS             complement(35625..35741)
                     /locus_tag="RFE25_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816025.1"
                     /translation="MINYAIYFNNININSIMALNDNNYQFEHVNERNEYRES"
     gene            complement(35846..36277)
                     /locus_tag="RFE25_000937"
     CDS             complement(35846..36277)
                     /locus_tag="RFE25_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2871 domain-containing protein"
                     /protein_id="HDU2816026.1"
                     /translation="MRRLLYSFLFYMIIGLFSGFFYRELTKAYDFTGTTQLSLVHTHT
                     LILGMFMFLILLPLEKLFKLSSYYLFNWFFYVYNIGVIVTIGMMVTKGFFQVTGKSYS
                     PEAFAGFAGIGHTGMLAGLLLLFFLLRQAILKEPRDESFKK"
     gene            complement(36484..37761)
                     /locus_tag="RFE25_000938"
     CDS             complement(36484..37761)
                     /locus_tag="RFE25_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDU2816027.1"
                     /translation="MNIFKNKLLWIAPIATMIILVIFSLAFYPAYNPKPKDLPIGILN
                     EDKGTTIQDKNVNIGKKLEDKLLDSDSNKIKWVKVDSEKDLEKDLKDQKIFGVAIIDK
                     DFSKDAMSKTQKVVMDSKKEEMQQKVASGEIPPQVVQQMKQKMGNQQVEVKQAKFKTI
                     VSEGSSLQGSQIASAVLTGMGDNINAQITKQSLETLTSQNVKVNAADINGLTNPVKVD
                     NEKLNKVKDHQAGGNAPFLMFMPIWIGSIVTSILLFFAFRTSNNIVVQHRIIASIGQM
                     IFAVVAAFAGSFVYIYFMQGVQGFDFDHPNRIAIFVAFAILGFVGLILGVMVWLGMKS
                     VPIFFILMFFSMQLVTLPKQMLPESYQKYVYDWNPFTHYATSVRELLYLNHHIELNST
                     MWMFIGFMIFGAVSSLVSAIVRKHSTKRTEVPS"
     gene            37922..38545
                     /locus_tag="RFE25_000939"
     CDS             37922..38545
                     /locus_tag="RFE25_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDU2816028.1"
                     /translation="MKEDRRIRKTKSSIKQAFTKLLQEKDLEKITIRDITTRADINRG
                     TFYLHYEDKYMLLADMEDEYISELTTYTQFDLLRGSSIEDIANTFVNNILKNIFQHIH
                     DNLEFYHTILQLERTSQLELKINEHIKNNMQRYISINHSIGGVPEMYFYSYVSGATIS
                     IIKYWVMDKQPISVDELAKHVHNIIFNGPLRIMAENRLHKSNLDSLT"
     gene            38591..39535
                     /locus_tag="RFE25_000940"
     CDS             38591..39535
                     /locus_tag="RFE25_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDU2816029.1"
                     /translation="MITSFRHSEDIDKHIIKTPLDHTASWINVVEPDREEIENLMEQY
                     NIPEDFIRDPLDSEESSRIEYDEDTGYSLIIIDLPIVNSTNRSVLSFVTIPLGIIIGN
                     GIIVTVCDAENEFLENLPKRDINLKFHSRFALEILTTIADHYNRNLRLLNKSRIRIEK
                     ELKNNITNKQLFKLMEVEKSLVYFLAALKGNDTIIKKLFRLPAIKRFEEDEELLEDLI
                     IENNQAIETTELHQRILESITTSYASLLSNDMNTIMKTLTLFTVLLTLPTLVFSFFGM
                     NVPLPIDDHSYISWIIVVGISLILVVIVSIFLWRKQKL"
     gene            complement(39620..41062)
                     /locus_tag="RFE25_000941"
     CDS             complement(39620..41062)
                     /locus_tag="RFE25_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sucrose transporter subunit IIBC"
                     /protein_id="HDU2816030.1"
                     /translation="MNYKQSAEDILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEA
                     LNIMDVVKGTFSTGGQYQIIIGSGTVNKVFSELEKLTGKEASTTSEVKAQSAKNMNPL
                     QRFVKMLSDIFVPIIPAIVAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMIN
                     VFANAPFTLLPILIGFSAAKRFGGNPFLGAVLGMILVHPSLMSAYDFPKAVEAGKAIP
                     YWDVFGLHINQVGYQGQVLPMLVAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAF
                     LTFSFVGPITRQLGYWLSDGLTWLYEFGGAIGGLIFGLLYAPIVITGMHHSFIAVETT
                     LIADATKTGGSFIFPIATMSNVAQGGAAIAAFFIIKQNKKLKGVASAAGISALLGITE
                     PAMFGVNLKLRYPFIGAIVGSGIGSAYIAFFKVKAIALGTAGLPGFISINPVHAGWLH
                     YFVGMTISFIIAITVTLILSKRKANKEVVE"
     gene            41245..41628
                     /locus_tag="RFE25_000942"
     CDS             41245..41628
                     /locus_tag="RFE25_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HDU2816031.1"
                     /translation="MKERGHIEQLWREEKYHVLLHSQQSYQMIRNALKTDLSLHQVQQ
                     MIDDALLIEPSIGSVCNAFDHMWGYFKKCANEEERKQSKLLKADFINGKIDTQTLLDF
                     LAELANKYDVQYLLQSRVLNTKRKR"
BASE COUNT        14347 a         7626 c         6095 g        15113 t
ORIGIN      
        1 gtcacttcat ttgatacgat tcttgataac ctattcaaaa ttccgccaaa taatataaat
       61 attatataaa tgccgatact tttaatcatt ttctactttt tcttcgatac ggaaacttgt
      121 tttcgaattg aacacttcac cagcttttaa aattgacggt gctttttcac catataaatt
      181 aatatcattt ggtaaaaatt gtgtttctaa tgtaaagcca gaatgtggtt tataaatatt
      241 aaatggacta tcccactcat caggctggtt aaaagtaaag aacacaacat gaggcatatc
      301 tgtatcgacc tctaacataa attcatgatt ttcaacatac attttatgtt caccaactgt
      361 aaatgggtga tcgagaccac caaaacgtgt catttgttgg cttaattgcg catgttgtga
      421 tgtaaaaata tcactcaatt ttatcttgtt atcttcaaac acttcatgta aatctagaat
      481 atcacctgta acaatatttc gctcatctaa tacatacata tctaattgat tacttgaaat
      541 gcgatgatta tcaacgacat tattatctcg attcaaattg aagtacacat gattcatagg
      601 actaaacaat gtgtcttctg atgcaactgc ttcgtattca atcgaccatt ggtgatccgc
      661 atcataaata tgtgtaatcg tcacatcgat atcacccggg aaatgatcat cagctgattt
      721 caacaccgtc ttaaatataa ctttaatttg agcaatttca tttctaattt cataatcaaa
      781 taacttattg tccaaaccat gacatccacc atgtaaatga tgttcaccgt tgtttttttc
      841 taactgatat tctttacctt tcaacttaaa tttagcatta tcaattctac cgctatatct
      901 tcctatagaa gcaccaaatt taaaaggatt actatgataa aactcatccg cttcaacaac
      961 atttccaaga acaatattat tatcatgata tttccaagac actactcttg ctccataatt
     1021 cgtaaaaata attttagttt catcattatc aattttgatt aaatctacac cttgtctttg
     1081 gtgctcaact tcaactatca tttttacttc tcccttctaa ccacaagtgt tcaagctctg
     1141 ctgggtagca acattactaa aacacctaca atacaaatga ttgcaccgat aacatcatat
     1201 ttatctggca tttgtttatc tacgaccatc gcaaaaatca aactcatgat gataaatacg
     1261 ccaccatatg ctgcatatac tcttccgaat gatggaaatg attgaaatgt cgcaatgaca
     1321 ccatataaca tgagtatcgc accgcctatt agcccaacaa gtgaagactg tccttcccta
     1381 agccacagcc aaatcaggta tcccccacct atttcacata agccagctaa tataaatata
     1441 aaaatcggat ataacatgaa atcactccat cacacatttg ctatcaataa tctatcggct
     1501 acatatcatt tgtttacatt tcttcttact tcacattccc attttaaaaa gttcgttttc
     1561 acattcatat tgtacacttt tttagacatt attctatagc taaatataaa aaaataagag
     1621 taacacgctt tcatcatcat tttatatgat aaatgtgtgt cactctcatc aattttattt
     1681 tttaaataca cgtttcattg aattaaataa gccacgttca aatgtaagta ctgaatcttt
     1741 atatgtttta attgcaatcc atatcaagac agctaccatt acaattgaga ttaaagaact
     1801 taagatgacc tcatatattt gaagccctga agtttgagcg cgtacaacta attgaaatgg
     1861 cgctaaaaac ggaatataac ttgtgattaa agcaagttgt ccatcaggat tatttatcgt
     1921 gaatatcgcg atataaaatg caatcatacc aagtaatgtc agtggcatca aagattgatt
     1981 taaatcttct attctagatg ttaatgatcc gaggatggct gcaagtaata catacgccat
     2041 aattccaaca atactactta taattccgac aataataatt tgccaagaca attgattcat
     2101 ttccacgtta aaaccttgta gcaagtcttt taagtcaaag gcaaaaatgc atataactgc
     2161 catcaataca attaaaataa tctgagtcac ggcaactgct ataacgccta aaattttagc
     2221 aaaaatatgt tggattggtg aaatacttgt aataatcatt tcaatgacac gcgatgtttt
     2281 ctcactagca atttccatag ctatttgaga tgcataattt aaaacaatga agaacattag
     2341 aaagataatg ccataagcta aagcatagtt gaaaatcttt tgtccttctg atactttatc
     2401 gacttcatca ttagaaatca ccttattatc aactttactt tgtgcttgta atttttgtaa
     2461 gtcttctttg ttgatattta attccccggc taccatattt gtttgaatag ctgtaagcag
     2521 tgcttgtact ttttgtgaat cttcatgact tactcgcttc tcactaatga ttgtcccttg
     2581 taacgtgcga ttttgattca ccttgataat ataagcttta tcaagtttat gtttttttac
     2641 ttctttttca gcatcttcta tagaaacttt agtaaactta gcatcactat ggaatgtatt
     2701 cgcctgttgc ttgaaaacct tatagatttg ttcattcggt gctgctacac caattttatc
     2761 tggaccatca tcaaacatgt taataatctt atcaatgtta gataggccaa tcattaaggc
     2821 agcaataata atcataaaaa ttacaaatga tttagcttta atttttttga tatatgtcaa
     2881 agtaaatgtc gcccaaaact tatgcatcct tgccaccaac cttctcaatg aatatatctt
     2941 gtaatgatgg ttctacaact tggaatcgtt taacataacc ttgatgtgcc acaacttgat
     3001 aaatatcttt ggctacgtct tcattctcaa tcgtcaactg aagaccttgc ttcatgtttt
     3061 cactatgaat gatgcctcta atgtttgtta aatctggtag tgttgtttct gattcaatga
     3121 caactttctt gttaccatta gatgcacgta catgattgat atcaccagaa acaacaagtt
     3181 gacctttatc taaaatacaa acatcatcac ataattcttc aacatgctcc atacggtgag
     3241 aactataaac gattgtactg ccccaatcat ttaagtcttt aactgcttct tttaataact
     3301 caacattaac tgggtctaga ccactgaaag gctcatctaa tattagtaat tctggtttat
     3361 gtaacatact tgctaacagc tgaatttttt gttgattccc ttttgataga ctatcaattc
     3421 gttttttgcg gttttcagta atatcaaaac gctcaagcca atacgatatt tgctgttgta
     3481 tttctgtttt tgacattccc tttaaagttg ccaaatattt caattcttct tcaactgtca
     3541 atttcccatg taaaccgcgt tcttccggta aataaccaat acgattgtac attgttttat
     3601 ctagtttttt accgttatac gtaatgtgtc cttcagttgg ttcacttaag cctaaaatca
     3661 tacgaaatgt cgttgtttta cctgcaccat ttcttcctag aaaacctaac attttgcctg
     3721 attctaactc taatgaaata tcatttactg ccgtcatctt gccaaaacgt ttcgtaacat
     3781 gttcaattac aagtcccata ctttgcctcc taaaaaaata tgtatttatc ttaatataac
     3841 atttctattc tctataaatg caatattttt aaagtgaatt tatttttaaa atttctgaaa
     3901 ttgaaatatt taaatagtat cttctttgca tgttaagtat cattagcgct agatacgcat
     3961 ttcccatacc tttattgcct tatttgtaaa aaaatatccc agcatcattg tgccgagata
     4021 tttatatcat tacaattgat tatctgtttc ttccggtgtt ttcggtgttt cagatgtcac
     4081 tggttgattt ttaattgtag acgggtattt tgggctttcg ccatatttat ttgccggctt
     4141 actgtcaaag cataggaata ctatcataac aattgttagg cctaaataaa caaaataaag
     4201 aagtactaac aaaatattaa gacccatcgg cattaatgta aaatcactgt cataataact
     4261 atcgataatc tgtaatacta tataaaatat aatactgaat actgtcataa tcattggaaa
     4321 taacattgtt cttgatatat cgtgaaatct tcgaacgcac aacgctaaat ttggaataaa
     4381 cgttgccaaa ctatagacaa aagtatacac agatgtaagg ataatcatca atatactcat
     4441 aactattaat gtttcgttat ctgccgctat agaaataaag actagaaata ggtttattat
     4501 tagcacacac acagctggaa ccataagtat caaatgccat agtgccatat accaatattc
     4561 actacgtctt gatctcccct taaaatttac ataatttttc caaaataata cgaatgattt
     4621 cataaaacct acttgaggta attgttccat tgtaatctcc ctttcgttaa tcatatttat
     4681 atttttaatt attgttaccg ttataattta caagattcat tatcaagcca cttcatttca
     4741 atcgtcattc actttggaaa atggacttta tatttcatca ctagtaaaat gaaaacccgc
     4801 tacaagtaca catctatatg gagactcatt tgaaagtcaa cgcttcgtta actatactaa
     4861 aaatatgtca tactgcaatg ttcacgttta aaagagtctc aatctctgca aataaaatat
     4921 tccataacaa agtatatact ttacattttt ataattctta acaatactat tttatcaaat
     4981 atttaccaca ataaaaatat ctttttcatt tttatttaat ttaatcatat aattgcgagg
     5041 agaatattat ggatttcgtt aataatgata caagacaaat tgctaaaaac ttattaggtg
     5101 tcaaagtgat ttatcaggat accactcaaa cgtatacagg ctacatcgtg gaaacggaag
     5161 cttacttagg tttgaatgat cgtgcggctc atggctatgg cggtaaaata acacctaaag
     5221 tcacgtcatt atataaacgt ggtggtacaa tttatgcaca tgtcatgcat acgcatttac
     5281 tcattaattt tgtaacaaaa tctgaaggta tacctgaagg cgtacttata cgcgcaattg
     5341 aaccagaaga aggtttatcc gctatgttcc gtaacagagg taagaaaggc tacgaggtaa
     5401 cgaatggccc aggaaaatgg actaaggcat ttaacattcc acgggctatc gatggcgcta
     5461 cgttaaatga ctgtagattg tctattgata ctaagaatcg taaatatcct aaagatatta
     5521 ttgctagtcc acgaatcggt attccaaata aaggtgattg gacacataaa tctttacgtt
     5581 acacagtgaa aggtaatcca tttgtgtctc gcatgcgtaa atcagattgt atgtttcccg
     5641 aagatacttg gaaataaatg ccatctttca ttgattacta tcatgaaaat gaaatctatc
     5701 tccttataag tcaatcaatc gtgccgccaa catgcggatg ggttgattgt ttttttgtcc
     5761 atcatatttt ttgattcatc tcctcttttt gaacttgttc ttaattataa aatataacaa
     5821 tagaattatt tataattatt aaatttagat gcattaatat tattgatatt attttcaaaa
     5881 actagaaata ttgatttgtt gcatgtataa tgttaaaagt gcccttttat aacgcttaca
     5941 tataaaagct tatttaggga gagggatatt caacaagggg gatttgaaaa tgatagaact
     6001 taatgcaatt acaacattat gtttagcctg tatactttac ttacttggta cagctatcgt
     6061 taatcacgtt aattttttga aacgcatttg tataccagca ccagtgattg gcggcttaat
     6121 ctttgctatt ttagttgcgg ctttggattc atttggcatg gttaagatta aattagatgc
     6181 ttcattcatt caagatttct tcatgttagc attctttacg acaatcggtc ttggtgcatc
     6241 attgaaatta tttaaattag gtggcaaagt cttgctatta tactttatgt tttgtgctat
     6301 catttcagtc attcaaaaca tagttggtgt atcactagca aaagtattaa atattaaacc
     6361 gttactagga ttaacagcag gttccatgtc tatggaaggc ggtcatggta atgctgctgc
     6421 ttatggtaag acaattcaag atttaggtat tgattcggca ctgacagcgg ctcttgcagc
     6481 tgcaacttta ggtcttgtat ttggagggct tatcggtggt ccagttgtaa aatatttaat
     6541 caaacgttat aacttaaagc ctcaacatag tgacgataca tttaaagatt atagccaagt
     6601 agcatataac gaacatttac atagtaaatt taatgccact gaagtattct tcattcaatt
     6661 tacaatcgtt gtattctgta tggcagttgg aagttatttc agtcatttgt ttacagctca
     6721 aacagggatt aatgttccaa tttacgttgg ctcattattt gtagctgtta tcgtccgaaa
     6781 tatctctgaa agttttaatt ttaatattgt agatttaaaa attactaatc aaattggcga
     6841 tgtcgcatta ggtattttct tatctcttgc gctaatgagc attcaattaa tcgaaattta
     6901 taaacttgct atacctctta ttattatcgt tttagttcaa gttgtcgtta tgattttatt
     6961 tgctgtttta attttattta gaggtttagg aaaagattat gatgctgcag taatggtagg
     7021 tggttttatc gggcatgggc ttggtgcaac gccaaatgcc atggcaaatt tagatgttat
     7081 tactaaaaaa tatggaaact cacctaaagc atatttagtt gtacctattg ttggtgcatt
     7141 cttaatcgat ttaattggtg ttatagtcat tatgggattc attcaatggt ttagttaaac
     7201 accaaactca taaataaaag aggaggcctc cgcctcctct tttatttatc ctcgatgtat
     7261 attcaagcta cgttgttcta tccatgacat tatttccgga ctaaatacga tttgtttttg
     7321 tgttaagtcg tcaatatttt tagcatctaa catcgtcatt attgatttca tgtgttcaat
     7381 aaatgattct acataagcta ctgtatgtgc aatgccatta ttttcaactt gatttaaaaa
     7441 cggacgtgac ataccagttg cctttgcacc aagtgctaaa cttttaattg catcgagtgg
     7501 tgtacgtaaa ccaccactcg cgaaaactga aatttcgctt tgataagccg ttgtttcaag
     7561 taatgactca actgtagact gtccccatga tgataagtaa tccatatctt tatttgcacg
     7621 acgttcattt tcaatatcta caaagttagt accacctttg ccactaacat cgacatactt
     7681 gacgcctatt tgttgtaagt catgcattaa ttctttgctc ataccaaatc caacttcttt
     7741 tataatgact ggaacagaca ctcgtgatac aatcgacgct atattatcta accaagtcac
     7801 aaattcacga ttcccttcag gcataactaa ttcttgagga gaattaacat ggatttgtaa
     7861 cgcttgtgcc tcaagtaatt caactgcttc caaagccttt tctactggta cgtccgcacc
     7921 aacattgcta aaaatcatgc cttcaggatt catttttcgc gcaatcgtaa acgtctcagc
     7981 catgcgtgga tttctcaatg ccgcatgtgt tgatccaact gccatcgcta agccagtttc
     8041 tcttgcaact acagctagct tttcattgat gtttttcgtc cactcgctac cacccgtcat
     8101 tgcattaata taaatcggat atgccatcgt taagtcaggc gtctgtgatg tcaaatcgat
     8161 atcatttaca ttaattgatg ggatagaatg atgcacaaaa cgcatcttat caaaatctga
     8221 atgcattgcg tcagattggg ccattgctat ttcaacatgt tcattttttc tctgttctct
     8281 ttgaaaatca ctcatgatta aacctacctt ttcgtcattt ctaatttaaa accatttttt
     8341 acgtctgaaa aagatgatta atacgacagc tataacaaac attacagcta agcaaatata
     8401 atatccataa tgtaaatgta atgccggcat atttacaaag ttcataccat aaatcccagc
     8461 tatgaatgtt aacggtgaaa atataactga tactaacgtt aatacttgca taatactatt
     8521 cattctaaat gacgtgtatg actcaaaatt ttctcgtatt tcgtttgtca tttcttgagc
     8581 agtacgaatg atattacgtt gcttaatcaa gtggtcatcg atatgttgaa tgtatagcga
     8641 atgtttatta tctataatca aatcaccatt ttgtttcatt gtatcaatta gctcttgcat
     8701 aggaaacagt acacgtttta ctttaatcaa atccgaacgt aacttaaaga cactatccat
     8761 gaccatttta ttaaagcgat catctacatg gcggtcttca aaatgataaa cactatcttc
     8821 aagtgcatat acaaagttga aatatttatc aaccatcata tctaaaatta atatgacgac
     8881 atctgcacaa tctaattctg catctaatgt attcatatac ttatagacta ctttatttaa
     8941 tgattccaac gtttgatgat gatatgttac taatacattg tcttgtataa aaatatttag
     9001 tgctattggt gaatagtttg accccataat actatgaaat actaagtatt gataatcttt
     9061 ataagattta tatttagctc gtggcatacc gttaattgca tcatccactt ctaaatcatt
     9121 aaaattaaaa tgtgctttaa accattcatt ttcttgttca ttcggttcat caaaatcata
     9181 ccaaacaata gtcgcatctt ttggtatctc tttgatatca tcaactactt taaacggttc
     9241 atatgtagtt tgataccgta tctttaaagc catcgatact ccccctaaat aacgaattct
     9301 ctattatttt atcatgaatt aaataacgtg tatgtcttaa tttattttag tatgatagtc
     9361 actaaggaga tggttattat caaacaactt tttacacata ctcaaaccgt aacatctgaa
     9421 ttcattgacc ataacaatca tatgcatgat gcaaattata atatcatttt tagtgacgtc
     9481 gtgaatcgtt ttaattacag ccacggtctt tctttaaaag aacgcgaaaa tttagcatat
     9541 acactattta cactagaaga acatacgaca tacctctcag aattgtctct tggcgatgta
     9601 tttactgtta ctttatatat ttatgattac gattataagc ggttgcattt atttttaaca
     9661 ttaactaaag aagatggtac actagcatca acaaatgaag taatgatgat gggaattaat
     9721 cagcacacac gtcgttctga tgcttttcct gaatcattct caacacaaat agcacactat
     9781 tataaaaatc aaccaactat cacttggcct gaacaattag gacataaaat agcaattcca
     9841 cacaaaggag cattaaaatg acagatgcat tacaacaaaa gattcatatt gaattactag
     9901 atttattaga tgatgttaag tttgaattaa cagaattaaa tgcacaaaaa gggttataca
     9961 ttaacggacc agcaaatcag ctacttaagc gtggcgttca tatggcttat gttcaaggac
    10021 aaaagcaagc catcgataat attatgacta ttgtggaaca gcagcttgaa gatcaacatt
    10081 tcctagaaga ttatgataaa tttcaaaatg aggttactca tcgcaattat gataaaacag
    10141 ctaactttgc agaacttagt gatattccac gtcaattcga taatttttta gatcaatttt
    10201 atcaaattaa agggcaatac tttatcatca cacatatcaa tacacttatt ggtgattttc
    10261 actcagaagc tcattaacaa ttagtctata taacccttgc tatattttca aaaacaaaac
    10321 ccaattacgt tttcatgtca aatatcatct tgcatgaaat cgtaactggg tcaattgtat
    10381 gttattagtt attttgtgtt acatcctcat ctatcgattt ggcaatttgt ttaatagctt
    10441 tatgtgattg tctaattgga taaattggaa aatcatgtac catcttagga taatcataaa
    10501 actcaatgta ttgatgatgt tgcaacatca tttgttcgaa tagcttcata tcaggatgtg
    10561 tcatttcacg tccaccacca aacatataaa ctggtggcaa tccttctatt gtgccattaa
    10621 ttggcgatat gcgcttatct gttaatggta ggccattcgc ccattttttc ataatctcat
    10681 tgacaccaaa ctgacttaga accgcatctt gttcgattaa ggcgtccgaa atatctttat
    10741 tagatagtgt tgcatctaaa attggtgaga ttaaatacaa tttattcggt aatggctgtt
    10801 gattatctaa aagagattgt acaaaggata atgccagtgc accacctgaa ccatcaccca
    10861 tgactacgac attttgatgt cctacttcag atactaattg atcataaaca cgttgtatcg
    10921 cttggaaagt atcgtcaata tgaaactctg gtgtctttgg atagataggc agtacaacct
    10981 catataatgt acttaaagtg attttatcca acaatctcca atggaacggt gatggttgta
    11041 gtgcattgaa tccaccgtga atatataaaa ttttcttatc aatttgatgt ctgaaattaa
    11101 agcgaaagac ttgcatatca tctaatgata atttttctaa atttgcttta acatttaatg
    11161 ttgaaggctg cttatgtttt tttctatttt caatttctct tttataaaaa aatctttcaa
    11221 catcttgatc atttttaaac ataatcgagc gattgtgaag caaatattta ttgacaacgc
    11281 tattcataac acggtttcta atcaatgtct taacctacct ttatatattt tatgtatcca
    11341 atgattgtct atcccctaca ttctttgcca aaaaaagtat ataatgtaga agatattttc
    11401 tttttcactt tcaaatttaa gactacaatt gaacagtgat ttttcatcat tataacagac
    11461 aactagacat attgataagt aaagaaaaga actttatacg gaggtgcctt gcatgacaaa
    11521 tccaaatcaa cgattagaac catttgatga gacatttcaa caaccgaata ttcatcgtgg
    11581 taagcgatat ggtaagaaaa aacgttcatt ggtaagcatg attattcaaa tcattgttgt
    11641 tatattaacc gcaatcgctg gatacagcat gtggaaacaa cccattttta atattgtctt
    11701 caccaaagaa tctgtagatt ttgatggcat taaaaatttt aacgagacaa ttggaaaaat
    11761 gcatcaatta aatattaatt tgggtaatat caatgattta caacaaggaa tcgatcgctt
    11821 aattttagtc tttaacggtt tctttattct atgtatcgtt agcctagtca taacaatact
    11881 gacaattgta tttaatcgca cagttctaaa agtagtaaat attttagtgt taacaattat
    11941 gttagtcatt actttgtatt tcagttatat tattaaaaca ctcgcacaag aaattgcaga
    12001 tgctttaaaa aaatattatt taaatgtacc accagatcaa gtgattacag aagctgacgc
    12061 tattcataac ggcatcattt tactgggctg tagcatcggt ttacttgtta taagcttatt
    12121 cttccgtaat cgcatgcctc gtttaaaata atgttatata gtagggattg ggacagaaat
    12181 gttattttca caaaattcat ttcgttgacc cacttcctgc tttttcttta ttaatgacct
    12241 actacgtcaa tgccaaattt taatataatt cctcttttat tttataaatc aacaaataaa
    12301 aaaagtatcg ataaccatat ttggcaccga tactttaaaa atcatgtccc cacaacataa
    12361 tttttgatta gtcacacttc aattaattta ttttatttat tcatgattgt tatttgagct
    12421 tgcttctaac ttttgagctg tagcttttgc ttttttatta ctttgtaaaa ataaacataa
    12481 aattaaagcg atgatgctaa atatcgttgc aactataaat gcatcattaa taccttcaac
    12541 tgttgctagt ttatttacaa attgtaataa cactttcatt gcgccttctt gaccaccata
    12601 ttgcgatgct aattcacgca tatgatcttg tacaacagga ttcgttttat ctaactcttc
    12661 cccaaaagct gataaatgtt gtgttgtttg tgttgtcata acagtaacta agattgctgt
    12721 acctatagag cctgctaatt gacgcatcgt atttaagaaa gcattaccat gagaggcaag
    12781 tcgtcccggt aacgcattaa tagctgcagt taccattggc atcattataa atgccatacc
    12841 aaatgaacga agtacataga tacccatgat tgtcatatat ggtgtatcca tatttaattt
    12901 agttaattcc catgttgcat aagtcatgac agcaatacca aagatagcta atggttttaa
    12961 accaatagta tctaacaatt tacctgcaaa tggtccaagt agacccataa ttagagaacc
    13021 aggtaataat aacaatccgg aatctaatgc tgagaatccg cgtaaatttt gtaaataaat
    13081 cggtaataaa atcataccac catataaact taacattaca accatattaa taattgttgt
    13141 taatgtaaat gttgggaatt ttaatacttc taaattcaac attggtgatt tcattcttaa
    13201 ttctcttatt acaaatagaa taataaagat aataccaatc gcaaacattg tttctatctc
    13261 aacagaaccc catcctttgt tccccgcttc tgaaaagccg tataacaaag caccaaaacc
    13321 aatcgtacta aaaatgatac ctgggatatc agctttaggg tttgttgtat attgatataa
    13381 cttaaaccat acaaaaccaa ctaagattgc aataataccg ataatgaaca taccgtaaaa
    13441 catcacattc caatggtaat tttgtacaat ataacctgat aatgttggac caattgcagg
    13501 tgctaaaatc attgcgatac ccattgtacc catggcagca ccacgttttt caggtggata
    13561 aattgtaata ataacaattg aacctaatgg cattagtaca cctgcaccaa tggcttgtaa
    13621 tacacgtcca accatcatga ttgggaaatt cattgaaatc gcacagatta atgaaccaat
    13681 tgtaaagagt actaacgcaa ctaaaaataa ttttcgatat gaatatttat taaatagata
    13741 cgccgtaatt ggtattaaaa taccgtttac taacatgaat cccgtcatca accattgccc
    13801 tgttgacgca gaaatattaa attccgtatt aatttttggc aaagcaacat ttaataatgt
    13861 ttggtttaaa atcgcaataa acataccgaa taataatgcc gctaatattt taccgcgtga
    13921 aacaccttca ccaaaaataa agtttttatg ttcttttttt attttttcat tcactttata
    13981 ttcttctgat tcaggatttt tagcagcaac tgcttcctca ccattattat tagtgaatgc
    14041 ttcttgatct ttctcagacc cctttgtgta accatttaga ctaacttggc tatgatcatc
    14101 ttgattgtca acacgcaact cttcatgcgt catacgttgt gtcgattgat cagttgtttt
    14161 gtctaaatca ctagctttaa atttagattg atttgattga cgtgtcgtaa attgttgttc
    14221 cttttgttgg cgtttgcctt tttttcttga tcttattaaa aataaattga taaccccaac
    14281 aataatgagc gctaaaataa tgtagctaat aatgaaggtc gtagtcattt aatgaccccc
    14341 ttaattttta tggattttta cttcagcgtt cattccagga acaacttgtt tagacggttc
    14401 tgattctaga gtgattttaa caggtattac ttgagaaact ttagtgtagt taccatcact
    14461 atttgatgat ggcattaatg aaaagcttgc agcagttgct tttccaatac tatcaacttt
    14521 acctttaata gaagcttttt gaccgtcaat agtcacatca acatctttac ctacttcaac
    14581 atctttaata tctttttcgt caatatttgc tgttacatat aaatcatcta aattgtatgc
    14641 ataagcgatt gggttaccag cttgcaccat tgaaccttcc ataccatcta atttggcaat
    14701 tgtacctttt tgaggcattt taagatccat atctttcgtt tcgccatctt gaccttgtac
    14761 agtaacagtt gctactttgt cacctttatc gagtttgtca ccttgtttaa cattaagtga
    14821 tttaatttgt ccagatgcag gacttgctat tttaatttga tcgccattta cttttgcatt
    14881 atcagttgtt acatagcttg ttgttttatt ccagaaataa aagccagcaa tcccaattgc
    14941 taacagtaca acaaccgtaa tgacattaat taatatcatc tttttcatga aacatttcct
    15001 cctatttgct tttaaaattc actttattta ttatagagac atgataacta aaaaaacacc
    15061 aacaattttt ataagagtgt tggttaaaat tcacaaaggt gtaacaatat gaaacgacaa
    15121 gccaaaatag aaattcaaaa cgcacttgtt gatttgatgg ctgaatatcc ttttcaagaa
    15181 atatccacta aaatgatttg cgcgtattgt aatattaatc gttctacttt ttatgattat
    15241 tacaaagata aatttgattt attggatacc atcaactcaa agcataaaga aaaattccaa
    15301 tttcttctaa gcgcgctaca tcataatttc gaaaatatta aacaggataa gcttaaactt
    15361 tataaattct tcattattat tgctaagtat atcaagcaca atgagcagtt tttcaaagac
    15421 attttagtta cctatccaat gaaaacatta ttcatagact atataaattt agcgagagat
    15481 tactatcaac aaattatgaa tgactatagt actacagtaa ccaataaaca gctttatgtt
    15541 acatatatca taggcggtca agctggggtg tttattaatt ggctttcgaa tggttgtaat
    15601 gaatcacctg aagaagttgc tgacatttta ttggctaata cgattaaact tcaaatccaa
    15661 taatacggtt tcattctaat aaagaaatgc tataaaacaa ctagataaag ttaaaccaaa
    15721 tggatagata atagtacata tgttacggtg ctatcaatat aaaaatgccg agatttccac
    15781 ataataatct cggcattttt atttttgatg ctaaattcat aggtctatga atagctcaag
    15841 ttttgttttt taatttttca attcaatata atagaagaaa ctatgtttat catcgatttg
    15901 ttttaaatac cttcatatta taaatctgta aaataattaa tataactgct gtagctataa
    15961 taataattat gtaaggtata ggattatctt caccttttac ccccactaat ggcgatgcaa
    16021 caccaccaaa taaaaactgc actaaaccta ataaacttga tgaactccct ctaccactac
    16081 tactttcatc catagctatt gtaaaaccaa ttgtcgcaac acctgtcact ggtgctatta
    16141 aaatgataaa tcctatcgct aaaatccaaa agttccaatg attaagcaat acaatcgtca
    16201 ctaaaattac accgataatc tgaatcatcg tcatgcctct catcaatttt tgtgagtcta
    16261 taaaatcaac aaggtaccca gtaagttgac ttgatataat gagcgtaata ccaattcctg
    16321 caaacatcca actaaattgt attgcagtca tgccataaat tttttgaata ataaacggag
    16381 acgcagaaat ataagtaaat aatattacaa atgtcatacc ttgaatgagc attggtaata
    16441 caaaacgtgg cgtcttcaat aatattttga agtttttaaa cattgttttt aatccactac
    16501 ttgactcacg atttgtcact gttaatgatt caggtacttt taataaagaa cctatgacca
    16561 tgacgaaacc aaagatagtc agaatgacaa agaccatacg ccagacagaa taatttaaaa
    16621 ttatgccccc tattgttggc gcaacaactg gtgcaatacc attaacaagc atcaataatg
    16681 ccataaactt agttagttca ttaccactat acatatcact tgctatagct cttgaaataa
    16741 ctgctgctgc gccacctgtc actccttgaa gaaatcttaa tgcaaccatc agccaaatat
    16801 tatgtacaaa aacaatacct aaacttgcta atgtaaaaat aatcatagct ataataagcg
    16861 gctttctgcg cccagttgaa tctgaaattg gaccagcaaa caaattacca aacgctaaac
    16921 caatcataaa catcgataat gttaattgtg cgttagacgt cgttgtttga aaatcatgtc
    16981 taatatctgg taatccaggt aaaaacatat ctatcgataa tgctccaatg gccgtcaaag
    17041 atcctaaaat aataataaat atcggtgaac gcttgttaaa atgcgttaaa tcattcatat
    17101 gactatctcc tttatataat gattagttta taactatcac gaacagaaac taaatttaaa
    17161 tatgctcttt tatatattag cattactcac aagtttcatg aacatcatta caacttataa
    17221 aaggtataaa atgatataaa cctcagcact ccataaattt tttcacaaaa aacaatccct
    17281 tcaaagtaat tcacactaat tgtaaatact ttgaaaggat gttgtttgta ttccatgaca
    17341 catgcatctt atttaagttt tatactctat ttttctgatg tcttgattaa ttgcaagcgg
    17401 tcttgcgagc cttgttcaag ctcatattct ttatctactt gcttaccgtt ttcatttatt
    17461 aatcttacgg ttgcggtaat cttatcacca tgtttttcag catctataat ttgtggtgaa
    17521 ctaatcatca ttaaacttcc tttagataca cgcttcttta catcatcata aaaagatgat
    17581 ccttttttta tatatgacga tacaaaatca aaatctgact gattaaacgc agcattattc
    17641 gctaaagaat atccagcaaa gaattctatc aatttgttct tcaagctgtt ttcttctttt
    17701 tctttctttt caacatagtc ttcgatatct tcactgtcaa aattcaaagt tatctctgta
    17761 ttgtatttta aatcgctggc tttaatcgtc ttcgtctgtg ttgtaaatgt tttacctttc
    17821 gctttacctg aagctgaaat ggtaatatct ttattttgtg gatatggacc atacgttttg
    17881 gaacttgaaa atgccatttc acggtcattt atagttactt ttttagaact atcatttaat
    17941 tttgtatcgc cttttaaagt tacagttata tttgcttctt caaaatcttc agtaacatct
    18001 accgtttcag aattactttg tctaaaatca aattttaaat agcctgcaaa atcaccgttc
    18061 tcagttgatt tcatagctgg aattctatat gtccccggta taaaattacc tattggcgtc
    18121 actttatttg cttcagctat aaccatcttt ttcttaccac cagatttaaa ctcatatttt
    18181 gttttttctt tcggcttaac aattggttgc ttggtaggtg cagtaaagct catattatcg
    18241 aaaaagatat aacgcgtgcc atttttactt acacgtaata tattttgacc agatctggtt
    18301 tgaatataag aagctacgct ggtcttactc ttattcaatt tatgtaccgt atttttaagg
    18361 tcgctgacaa attgcttaag cccaacttca tctttgatat agttaatgta tactttcgct
    18421 tcttcagaat ctactttatt atctttagta cttaataatg ttgctacttt ttgtttatca
    18481 ttattctcaa tcgcattcac taatatttta gtttgcgctt caggtgaatt gaagtttctt
    18541 agtaaaaaga acaatataat aattaagatt aaaatgaaaa aaccaattgc ccaaggcacc
    18601 atttttctca tcttgatgtt attagtttgt atatcttcat cggttgactt tctatataat
    18661 gcttgacgac tatcaaattt atgtccacat tgtgtacata tctgtacatc atcttgtgct
    18721 tgttgtccgc acttcgggca agatttcata ctttcacctc aattctgttc ctcttcaatt
    18781 gttatatgta tatcacaaaa attatttcat tattttacca ttattatttt acaaatatta
    18841 tcccaagaat acaattcaag aaatgattaa ctttacttta gaattgtacc ttattacatt
    18901 atttatgaaa gtactctctc aattataact aaaaagaagg tgttcaatac atacatattt
    18961 agtcttatat ttgaacacct tcaaaaacct atttatgatt gctatatgtt ttaatgcgat
    19021 gattgatgac ttctaatact tgccttacat tttcaatatc ttcagaattt aaatcattag
    19081 taatatcttg cgcaatatct gtcataatcg cattacgttc tttcaaatat gctctacctt
    19141 tgtcagttaa ggttatgaat ttcaaacgtt gatcaatatt taaatttggt ttatctaact
    19201 taactaattt agcatcgatt aactttttaa ttcgtcggct tactgcggcc ttatttactc
    19261 cttgtctttg cgtgatttca ctaattgtca aaggttcttt atttaacata cctaatacgt
    19321 tagactgctc taatgaaatt tcatattcat tttgtaaatc tttcaacatt tttgcagtta
    19381 atgcgttaac gttatttata aactgctcta aaaattgaat atggtcttgt aaatgtttta
    19441 ccataattat ttctccctaa ttactatttt tataaagtat cctcagcaat cattgtatcg
    19501 cacatctaaa aaacacaaaa atattgaccc atatataata taacaaatta agacttacat
    19561 gttgctgcgt tctccttgct ttaataaatt aaatcatcta catttatatt taatatttat
    19621 tataagcgag gtgtcagtat gttattgaat ttattattaa tatttatact tatcgttatt
    19681 tgtccgttaa ttttcaacta tactctgacg ttaaatttaa catgctacat cttagttgtc
    19741 atatcgatat ttttgtcact catctatagc atcatgacct atactttccc ttggtctatg
    19801 tttgtaacat ttataataat cagtattatc atgctattca aacatagata tttattttct
    19861 catacttcta gtcgcttatt tattaaaaaa ttattatctt tttcatataa atttgtactc
    19921 tacacatcag cacttctatt tataagtacg attcagtcac ctattgtgaa aggtttgtct
    19981 atgtggttag ctatattatg tctttccctg ttactaacct ttatttgtta tctcgtttgg
    20041 acagtatcat atagacatag atcatacaac aaagaagttg atatcataat tgtgttaggt
    20101 gctggtattt ttaccgaatt tgtcacacca atgcttgcag cgcgtttaga ccgtgcactt
    20161 gatatctatc aacaacaagc atcagcaaca aagattattg tatctggcgg acaaggacca
    20221 gacgaaccaa tttctgaagc tttagctatg caacgttatt tgattgcaca tggtgttgat
    20281 aaaacagata tactaatgga atctcactct ataaatacat acacaaactt tttatattct
    20341 aaacaaatca tcaacaattt gtatcatgaa gcagttaaaa ttgtttgtgt aacaagtcag
    20401 tttcatgtat tgcgcgcctt acgactagcc caaaaattag gtttatctat cgatggtgtc
    20461 ggaagtcata caccatatca ctttttctta catgtgctca ttaaagatta tctaggcgta
    20521 atgtatcagt atagattgtt attaacgtta tattgttcaa gtagttggtt tatatgtctt
    20581 tacgccgctt ttatttataa tagttaatcc acaaacaaac tattattata ggttgtttct
    20641 aatattgcgt caaactatct ttaaatattc gttaatcctt gattagacaa ttgttatatt
    20701 gaaaataaat aaactaaagc acgtcatcat tttatataat agtgacgcgc ttttttgtaa
    20761 acccaaatcg tattctgtta tctaactttt atactactat gtcttaaatc attaacattt
    20821 agcgtcttta caagccacta atcagttatt ttgccatctt ctaattcaat cactcgatct
    20881 gcatattcaa ataatcttcg atcgtgtgta atcataatac caatcatttg ttgttcttta
    20941 atttgttgac gtatcatctc aacaactttt gttgctctat cggcatctaa acttgctgtg
    21001 ggctcatctg ctaaaatgat tttcggatta ttcataaatg ctctcataat cgcaacacgt
    21061 tgcttttcac cgccagataa ctgatgcgga tatacattca agcgatcttc taacccaata
    21121 tttttcaaaa gttgtattgc tcttgttgaa ctttgttgtt tggtcattcc cgcttcttgg
    21181 cctacgagtg tcaattgctc tatcactttt aaataaggaa ctaaatgtga agattgaaaa
    21241 ataaaaccaa tatcttccaa tcgcaaatca ctaggacgat gctgtttatc aaacaatggt
    21301 gcatcattgt aaagcactgt accactcgtt tgacttaaca atccgcctaa tatcgttagc
    21361 aatgttgttt tcccagaacc agaggcacca tttaaaatga caaattcccc ttgttccact
    21421 tcaaaattaa taccttttaa aacttttgtt tcagacaaac cttctccgaa atttttgacg
    21481 atatctttaa cgactaatgc cattattctg cacctccaat tgcttcgata ggatccactt
    21541 taaataattt gataaatgat agtgaggcac ctaaaatcgc tactaatata aatatcccca
    21601 ccattaataa aatattttgc gttgttaagt aaaaaggcat cgttaccggc atcataaatg
    21661 atagtcctac tatgatgatc acagcaatac ctaccccaat tattgttagt gttaaaattt
    21721 gtaaaactaa cgcactcaat aaatgtcttg tcttaatacc aattgctttc aaaatgccaa
    21781 tttgtgatat tttttgaatc gtcataacat agaaaaatgc acttagaacg attgctgtaa
    21841 tagcaaacaa actaacaatc atcatattta acggtgcttg ctctgcttga taactcgcaa
    21901 tattacctgt taaatctttt tcactcacaa cttgaacgtc atttatttta ttaagctcat
    21961 cacgttgttg ttgtgttaaa tttttcactg gataaaatgc cgtattaacc ttattcaatg
    22021 cattaaatcc gttatcgttc aatagcacaa tggaactatg cgcatacatt gtgtcgttta
    22081 aaataccaga aactctataa ctagttgaat tatttttaaa atgtaatcta tccccgactc
    22141 taatgttgtc tgcagctaac ttatcattaa tagcgacctc atgagcattt ttaggataat
    22201 cacctttttt aagttgtatg cgttgttgtt taacgtcatt cattgtaatc acatcttgtt
    22261 ctttattaga taatttcaat gtttgaatat tcattttata tggttcttga tgaattacct
    22321 ttttaatttg attctgttgc gtatcactaa gttgcgattt ctcaatttgc ggctctttca
    22381 ttttttgaac aacatattca tcattatcaa agtgttcaaa taacgaaata ttctccctac
    22441 caagcccttg agctaaacca ctaataaata acaccataat acttaataaa agaatgatta
    22501 atgtgattaa aatataacga aatttgtaaa acataatctc ttttatcgct aatttcatat
    22561 cgattcactt ctccctattt cttctttagc gtcagtataa ggttgaaata tgaactcaat
    22621 atgaacaatt gtttttttac gcaaaaatat tttacatgta taataaatga aaaagataag
    22681 ggagtttata gctatggtgc aatgtcttgt tgtcgatgac gatcctcgaa tcctaaatta
    22741 tatagctagc catttacaaa cagagcacat tgatgcatac acacaaccaa gtggtgaagc
    22801 tgcattaaaa cttttagaaa aacagcgtgt cgatattgca gtggtagata ttatgatgga
    22861 tggtatggac ggctttcaat tatgtaatac attaaaaaat gattatgata taccagttat
    22921 tatgttaaca gcgcgggatg cacttagtga caaagagcgt gcgtttataa gtggtactga
    22981 cgattatgta accaaaccct ttgaggttaa ggaacttatt tttagaattc gtgcggtatt
    23041 acgtcgatat aatatcaatt caaattcaga aatgactatt ggcaacttaa cgctaaacca
    23101 atcctatttg gaactccaag tatctaataa aacgatgacg ttaccgaaca aggaatttca
    23161 attattattt atgcttgcag cacgtcctaa gcaaatcttt actcgtgaac aaataataga
    23221 aaaaatttgg ggctatgatt atgaaggaga tgaacgaaca gttgacgttc atattaagcg
    23281 actacgccaa agattaaaaa aattaaatgc cacacttaca attgaaacag taagaggaca
    23341 aggctataag gtggagaatc atgtttaaaa cactctatgc tagaattgcg atttattcca
    23401 ttacggttat tttatttagt gcattaataa gttttgtatt aacaaatgtt tactatcatt
    23461 ataatttaaa agcatctaat gacgcgaaaa tcatgaagac acttaaagaa gcaagacaat
    23521 atgaacaatc agctaaacca acgcacattc aacaatattt caaacattta gggcaaatga
    23581 attaccaaat aatgaccgtt gatcaaaaag gtcataagac attttatggg gagccattta
    23641 gagaagatac tttatcacaa aatgctatta acaacgtatt aaataataaa gattaccatg
    23701 gtattaaaga taaaccattc gcattattcg taactggatt tttcgacaat gtaacagata
    23761 atactgttgg tattaacttt aagacaaaag acggttcaat agcagtattc atgcgtccag
    23821 atattggaga aacatttagc gagtttagaa cattcttagc cgtcttgtta atgttgttat
    23881 tatttatctc gatttcatta gttatcgcat caacctattc aatcattcgt ccagtaaaaa
    23941 agttaaagct agcgaccgaa cgcttaattg atggtgattt tgaaacacct atcaaacaaa
    24001 cacgcaaaga tgaaattgga acattacagt atcactttaa taagatgaga gagtcattgg
    24061 gacaagttga tcaaatgagg cagcattttg tacaaaatgt atctcatgaa atcaaaacac
    24121 cattaacaca tattcatcat ttattaagcg agttacaaca aacttctgat aaaacattaa
    24181 gacaacaata tataaatgat atttatacca ttacaacgca gctgagcgga ttaacaactg
    24241 aattgttact cttatccgaa ttagataatc accaacattt attattcgat gataagattc
    24301 aagtcgatca actcattaaa gatatcattc gacatgaaca atttgctgct gatgaaaagt
    24361 cgttaatcat tttagctgac ctagaatcaa tcaatttcct aggaaatcaa cgtttgttac
    24421 atcaagcatt gagtaattta ttaataaatg ctattaagta tacagatgtt ggtggtgcca
    24481 ttgacatcgc tttgcaacat agtcacaaca atatcatttt cacaataagt aatgatggtt
    24541 caccaattag tccacaagct gaagcacgtt tatttgaacg tttttataaa gtgagcaaac
    24601 atgataatag caatggttta ggtcttgcaa ttacaaaatc catcattgaa ttgcatcatg
    24661 gtacaatcca attcacacaa agtaacgagt atgtaaccac ctttactatt acactgccaa
    24721 ataattcaca ttaatctcta cctcctgaaa aaacatttct gtttttattt caggaggtat
    24781 cttttatatt gattagcgct ttctagccac ttaacattta atttctacca ttcaacaaaa
    24841 tttaaatata tcgatggtca tttatggttt aataattttg aaggaggcat taacctatga
    24901 tgaaactcaa tttatttatc aatgcaaatg agacggaatc ttatattgat atacatgcac
    24961 ctaaaatgaa tgatcacgtt caaagtatta ttaatgcagt caatgattta gacaaatcac
    25021 atacattagt cggatacata gacaaagaaa tccatatcat taatgtatca gatgttataa
    25081 cattccaagt tattaataaa aatgtaacag ccattacaag caatcaaaaa ttcaaactaa
    25141 aattacgact ttatgaacta gaaaaacagt taccacaaca tttcattcgc atttccaaat
    25201 cagaaatcgt caacaagtat tacattgaaa aattattatt agagccaaat ggacttatac
    25261 gtatgtatct taaagatgca cactacacct attcttctag acgttattta aaatctataa
    25321 aggagcgctt atcaatatga aaaatttgaa aaactcatta tttattagct taatcattgg
    25381 tttgtccctt tcactgttct ttagtatgtt atttgcagac ggcaaatatt atccactgaa
    25441 cccacaatca actattggca ttttgtatta taatcatttc acagaaacta ccgtaatgtt
    25501 gatttctatc attttatggt tactcatagg cgtcgtcttt ttccttggag attttatctt
    25561 taaatacaca gattggagca ttactaaagc aactataatg catttcataa caacgtatgt
    25621 cggattcttg cctttagcaa tgcttgccgg ttggtttcca ctaacagtgc attatctaat
    25681 catattcaca attatcttca ttgtgattta tgtattaatt tggataattc aattctttaa
    25741 aaacaagaac tacgtagaca ctattaacga gcaactgaaa caattaaaat gatttttatt
    25801 aaccactaaa aaacggtaat gtctatcaca ttaaaaaaga cattaccgtt tcgtttatta
    25861 tttaacttgt aaatacttag ttacttcttc attaattttg tgatataaat cctcatgatc
    25921 tgttaagcga taaccaaatg acggcaccat ttctttaatc tttggttccc accctttgaa
    25981 ttcatcacga tagcatcgct gtaaaacatc aaacataata tctacagctg ttgacgcacc
    26041 aggtgatgca ccaagtaatg cagctaatgt gccatcatct gacgtaatga cttcggtacc
    26101 aaattgtaag ttacctttag aatcctcagt atccttgatt acttggacac gttgccctgc
    26161 tgtaatcact tcccaatctt catttttagc atttgggaaa aagactctta aatcatccat
    26221 acgctcatca ttagataaca tcaattgtga cactaaatac ttcgtaagac tcatttcttt
    26281 gatacctgca gataacatcg tcacgatatt atttggttta accgatttaa ttaaatccat
    26341 atgtgaacct gtttttaaaa atttaggtga gaaacctgca aatggaccaa ataacaatga
    26401 acgcttgccg tctacaaaac gtgtatctaa gtgcggcact gacattggtg gcgcacccac
    26461 tgctgctttt ccgtacactt tagcatgatg acgatcaatc acttcttgat ttgtacagcg
    26521 caggaataat ccacttactg ggaaaccacc aatatgtttt gattgtttaa tcccagtctt
    26581 ttggagtaat ggtaaactcg caccgccagc accaataaat acaaaatcag attcatatgt
    26641 tgtcgtttca ttagtttcta aatctttaac tttaactagc catgccccag atttctgttt
    26701 cttgatgtct aatacattct gcttatattg aattcccaca ccacgttgct ctaaattttc
    26761 aaataacttt gcagttaacg caccaaagtt aacatctgta ccagtttcat cataagttaa
    26821 agcaattggt tcatcagact tacgaccttc aatcattaac ggtacccaag atttcatttc
    26881 ttcttcatct tgcgataatt tcattttttc gaataaaaca cttttcttta acgttgcaac
    26941 acgacttttt ataaaagcta cattatcttc gccaatgaca aaactcatgt gtggcaccgc
    27001 ttgaataaag cgatctgggt tatctaattg tcctgtttta actaaatatg cccaaaactg
    27061 ttttgaaatt tggtactgct catttatctt aattgcttta ctacaatcaa ctgtgccatc
    27121 cttaccttct tttgtatagt tcaactcgca aagtgctgaa tgccctgtac cggcattatt
    27181 ccatacattt gaactctctt cgccaggttg tgctaatttt tcaaacactt taatattttt
    27241 ctcaggtgat aattctttaa gtaatgttcc taatgttgca ctcataatac cgccaccaat
    27301 taagatgaca tctgttttgc tatgttgtgt tgtcataaca aatacagtcc ccctttttaa
    27361 aatgaataat ggaacgttcg agaaatacga catattaata ccactttaaa tcaataagtg
    27421 tctcaatagg ttcccatggt gatgctctat tactatctac tatgtatatt aatattttat
    27481 aataacgaaa ctactttaat tatatacttt atgtgcgata gcacaaagac aaaaccacaa
    27541 accttaacag ctatcaacca atttaatttg attgctgatt actcactatt cattttaaca
    27601 taaagcgcta ccattattat aatgtcaaac ttctttcatt aatgatccat aaaaaaaaga
    27661 tgagatgtta gaaaacatct caccttctgt atatttatat tttgaaatac gtttttttat
    27721 aataatgaca agatgaaagt ccaaatacag atgaatatta gtaaacatac actgtatttc
    27781 aatgtcattt ttaataattc tgattcctta ccaacttgtt ttactgctgc agttgcaatt
    27841 gcaattgatt gtggtgaaat caattttgcc gctacaccac caactgtatt agcagataca
    27901 agaagtgaac cacttgttcc aatttgttgt gcaacagaag cttgaattgg tgcaaataat
    27961 gaattgttat ttacaactga tcctgtcata aacacaccta tccaacctaa gattggtgat
    28021 agaactggga agacattacc tgctttagct ataccttgac ccattgctgc acttaaacca
    28081 ccataagttg tgattttaga aattgctaag atgaaacaaa ttgtaagaac tggtaaccac
    28141 aactctttaa atgtaacgcc gaataatcta acagcatctt taaagttaac ctttttagac
    28201 attaaaattg taataataat agttaataaa atagctgtac ctgtttgtcc aataatattt
    28261 aaagtcaata ctaatggttt atgcgtaact tcgctgattg ttccaggtaa gttgaattta
    28321 aatactaatg atgataaagc accatttggt aagaataagt ttttaaagaa tggcgcactc
    28381 caaatcatta caatgactgt taatacaatg aatgggctcc atgcatgtaa tactgctttt
    28441 gcagaatgtg cttttgcagg ttcaatttct tcatctttat taacacgata aatgtgtttt
    28501 ggttggaatt ttttagaaaa tactgctaat gctaacattg ttaataacgg tggaataata
    28561 tctgctaatt caggtccact gaatacagtt aataatcctt gagtaagtgt ataagtgatt
    28621 gaaactacta aaattgctgg taatgtttct ttaacacctc taaaaccatc aataataaag
    28681 ataagtaaga atggaataat gaaatttatg attgccaatg ttaaagttgc tgattgagaa
    28741 acacctaata ctgaaacatc tccaggtaat ttcaacgttt ctacaacacc tacagggata
    28801 ccaatcgcac caaaagcacc agacgctgca tttgcgacta aacataacat cgcagctttt
    28861 aatggattaa atcctaattg tgttaataaa agtgcacaaa ttgcaattgg tacaccaaat
    28921 cctgctgcac cttctaaaaa tgcgttgaat gcaaatccaa taagtaaaac ttgaatacgt
    28981 tggtcttgtg aaatatttgt aatactatct tgaattgtta aaaattgtcc agattcaaca
    29041 gtaattttgt ataacaatac tgccatcata acgatatagc caatcggaat gataccttgg
    29101 aagaaacctt cgactactgc accagaagcg ataccaactg gcaatttgaa aaatggtatt
    29161 gcaattagta atgttacaac aagtgttgta atagctgcat aaataccttt cattttaaaa
    29221 acagttaaac atagtaaaaa cagtacaatc ggtattgctg caattaaaga cgataataat
    29281 aaattatcaa atgggttaaa cgtatttact aacataggct gactcttctt tccataaagt
    29341 agtagtgtaa ttgcttcatt aaaatcatgc tctggctata gcattttgtt atcgataaca
    29401 ttttacagaa cagtgagatt aatgtgattt ttttcacaat taaaatatac cattttttca
    29461 gactattaac aatatcactt tcctatttaa ttgttttatt tttcatttta aatctgttca
    29521 tcaaaatgaa ttgtacttaa tgtaatgaag taacttatac tattcatgaa ttttacataa
    29581 gaccgtgcta aaataaggaa gatactacga tgagaaatgg aagttatagc aatgattaaa
    29641 cagataaatg tttctaatat gcaaaagttt gaatctcaat taatgaaagc tcagtctgaa
    29701 ggttatacac atgtcgttcc atatgcaaat gagataatga tttatcaatc gatgttagat
    29761 gcggttcaat tatatcctaa gtctatcgtg gttgattata ctgtggatgg acaatacaaa
    29821 aatgattgtc actatttcgg tcaatcatcg atcaacattg ccgattgggc tcaaaacaat
    29881 aattattatc ctaacctgat atatgcgatt caacagactc ttgatttaat acattattac
    29941 tctgtagaaa cgattttcga tttagcttta ttgacacttc tgaaaggtga tttatcaatc
    30001 gatggtcatg tcgtttttga ttttaaagcc cctatagcaa caagtgcttc aatatgggaa
    30061 actattaaaa ctattgaaga ttttgatatg atgtctcagt tttatttgaa taaaatggct
    30121 tatattgatc atcatcctat accttttcgc aaccttttta tcgaggattc agaacaactt
    30181 aattcgccag ataattggtt gtattctacc aagtttatgc tacctaaatg gttatataaa
    30241 atagcaaagc aacgtgctga taacaaacaa ttacaaaact tcggcctgta tacgaagcaa
    30301 ccaaacgttt taaaagatca catcgttttt atcggtgatc atcatcaata tataggtaat
    30361 tcaaaatatt tatttactta cttcgttaaa cataatccaa tgactgcctg ttattttgtt
    30421 actgacgatc gtcgcggacc acatttcata tcacctaagt ctgaaaaagc tgacgaattg
    30481 attaacagcg cacgcgtagt tatagttgaa aatgatatac ctgaaacgtt acaaccaaac
    30541 ggtactttaa ttcaattaca tcaaggcaca ccaataatgc aattattttt agatagtaaa
    30601 gagcctatta aaaatataga aacacctttt tatcgtgcta aaaggtataa tcgctggttg
    30661 caattcgatt atgttataca ttctgctgat gatattagcc acttttatca aacggctttt
    30721 cctagtcacc aagcaaatgt attggcttat ggtaatccta aacaccaata tttactacaa
    30781 aagcgtaacg aaagtactac tcaacaacag tataagaaat cgtttaaaat aaatgatcaa
    30841 aaaccagttt tattatacgc acctattgga ttagtgagtg cgcaacaatt accactatca
    30901 gatgctttat tcaaagccta tcatgttgtg gttcagggtg ttgatgaagc gatcttacca
    30961 gaagaggcgc ttgttgcacc aaagtatctt agtgctcaag acttaattct aatgtctgat
    31021 gtcgttatca ctgattactc aaatataata tttgatgcga tggctataga caaaacagta
    31081 gcattataca ctccaaatca cagtcaatac attgagtctc aaggtgttaa cgaagatatt
    31141 tggcgtcatc tatcaaaaat ttggtataca gaccgacaat tattaattaa taatttaatt
    31201 tcccaggcaa taccagtgat taaatatcca caaatacaac ataaagaaca accattagaa
    31261 tctatttcac aacttatatt gtctaagatg acatctaatc aatagtgttt aaatttctca
    31321 gtggctgtga atgaggttta aaagtgctat aaaacgtaaa cttttatact ttaaaatacg
    31381 caaaaaacgg taaaccctaa ttcatattat agagtttacc gttttatttt tttaacttgc
    31441 atcatagtta tattaacatt attgttggta gtttggatca gtaaccattg cttgtccagt
    31501 ataatcaacc gttacaattg aatattttcc atttgcattt gggtctttaa aactaaacac
    31561 atacttatag ttgccattat gttcttcaat agaataatca ttatacactt tattattact
    31621 accaaattta tttgcttcat tattagccgc atttaaagct gtttggaaat ttggcaattg
    31681 ctgtaaagct tgagttttat ttccattaaa cggataaatt tgacgtgcaa ccggcgcggc
    31741 attttgtcca taatatggtg caacgtaact tgatttttga ttattacttg attggttatt
    31801 atttgtttgg ttttggtcat tgtttgttgc atttgaatta gattgttgct ggttatcgtt
    31861 tgcactatta tctttattat ctttgtttac gtctttacta tcatctttat tgtctttctt
    31921 atctttagat gaatcatttg tttttttatc ttgttgttca gttttcgctt tatcatcttt
    31981 ttctttatta ctgtcttttt gttggtcact atcttgacca catgcagcta aaaataatga
    32041 taatgctagt aaccctgtaa ctaatctttt catacatatc tcctcctata attcgatatt
    32101 cattgaataa gcttgaaata catatctacc atgtgtatca tttcatggct tgttaccaaa
    32161 gacgtcaaca ttaatatgat ttgaattatc acaataccca taactacaat ctaaggttct
    32221 ttttattata ccctaatttt tgttcattat tatttaattt ttgtgaattt tatgttttct
    32281 ataaatttaa ttattttact ttaacaattc attacgcatt tagcatttca aggcatacac
    32341 aatatttatt actatgattt cattttatct gctgcaaaaa caatcattat aactcttttt
    32401 ccataattaa atctgtatcc gttacatcac ctgtttgaaa atgatgttca ccaaccactt
    32461 taaatccatg acgtttataa aatgcttgag cacgaggatt atgctcccaa actcctagcc
    32521 aaattttatg tttattatgt tcttgagcaa ttttttcggc caattctatc aattgtgaac
    32581 ctcttccgcc accttgaaag tctttcaaaa aatatatgcg ctgcacttct aaataggtct
    32641 cccccatttc ttcagtttga gcactattaa tattcatctt tatataacca acattcgcac
    32701 catcttcttg ataaaaataa tgaaatgaat ctacatggtt aatctcttgt gtaaattttt
    32761 ctacagtata attgtcttta aaaaattgat caaaatcttt gtcatcatag taagaaccaa
    32821 acgtgtcata aaatgttcta gttgctaatt caactaattc actagcattt tgttctgaaa
    32881 tttctttgat tatcccagcc atataaatcc tccaataaac agtgatcgaa tcaaaatatt
    32941 acttatgtta tttttcagcc aaaactattt aaaaatacat taacacaaat caattacaaa
    33001 ttgtattgat tgtgtgtaac atcaataaat gatacattta ttccagtaaa atggccgtat
    33061 tttcaaaaga gaaaaagaga ggatgtatcg ttgtgataga aacatttaaa gcgtttgtaa
    33121 ttgataaaga tgagagcggt aaagtgacac caactttcaa acaattatcg cctactgatt
    33181 tacctaaagg agatgtgctg attaaagtac attactctgg tataaattat aaagatgctt
    33241 tagcgactca agatcataat gcagtcgtaa aatcgtatcc tatgattcca ggaatagatt
    33301 tagctggaac aattgttgaa tccgaagcac caggctttga aaaaggagaa caagtaattg
    33361 taacgagtta tgacctaggt gttagccatt atggcggttt tagtgaatat gcgcgtgtaa
    33421 aatcagaatg gattatcaag cttcctgata ctttaacatt agaagaatca atgatatatg
    33481 gcacagctgg ttatactgcc ggtttagcaa ttgaaagact tgaaaaagtt ggaatgaata
    33541 ttgaagatgg tcctgtactc gttcgcggtg cttcaggtgg tgtcggtact ttagcagtac
    33601 tcatgcttaa tgaacttggt tataaagtta tcgcaagtac aggtaaacaa gatgttagcg
    33661 atcaattact tgaacttggt gccaaagaag ttatcgatcg acttcctgtt gaagatgatc
    33721 ataaaaagcc actcgcatca tcaacttggc aagcttgtgt agaccctgtt ggtggcgaag
    33781 gtattaatta tgttacaaaa cgtttaaatc atagtggatc aattgcagtt attggtatga
    33841 ctgccggcaa tacttatact aattctgtat tccctcacat tttaagaggc gtaaacattt
    33901 taggaattga ctcagtattt actgctatga aattaagaca gcgcgtttgg cgtcgtctcg
    33961 caaaagattt aaagcctgaa aatttacatg agatcaagca agttattaca tttgatgaac
    34021 ttccagaaca acttaacaaa gtaattaatc atgaaaataa aggccgcatt gttatcgatt
    34081 tcggtgtaga taaatagtat tcatgaaaaa gacatcccgt tatgcgagat gtctttttta
    34141 atttagtatt tgatatacat accgcctgaa tctggttcgg taggcataaa tccaaatttt
    34201 gcatataatt tatccgctgg gtagtctgcg atcagactaa cgtatgcact ttcgacagat
    34261 acatttttaa tatacttcat aatatgttcc ataattagac tgccgtaatc ttgaccttga
    34321 taacttttcg aaacagcaat atcaacaatt tgaaaaacag ttccgccatc gccaatcact
    34381 ctacccatac caattaaccg atctttatca tacaaggtta ctgtaaataa ggcattaggt
    34441 aatccttttt cagctgcttc gcgcgtcttt ggactcatac ctgcgttaat ccttaatgcg
    34501 caataatcct cgcaagtcgg aatatcatat gtcactttaa ccattattta ccccactttt
    34561 catcacacaa tatatcaacc tagtataaat gtttatttac aatagtctta ttcgcttctt
    34621 taaacacttc atgatgactt gaaacataac cctctgcatt cgcatctggt tggatatatg
    34681 ttttagcaag gttcgctgca tttgcaccat cactaaatgc acttgcaatt agatgtgatt
    34741 ttgcatcatg ataaacaata tctccacacg catagatacc aggtatacta gttgtcgtat
    34801 taccaaatcc tttaacacga caatcatcat gcatatctag ctttgaagat gtttcactca
    34861 ataatgtatt acaacgatca aacccatgac taataatgac atcgtcaaat ttaactgtat
    34921 gcctatcgcc actttcaaca tgttccaaaa caacttcact tatatgcgtt tcatcatcat
    34981 tgccgaccaa gtatttaata cgtgtttttg ggcatagttt cacatttaaa tctgtcacca
    35041 acgttttcat cgcttcatga ccacttacat cttcttttcg ataaacaact gtcacgcttt
    35101 tagcaatctt ggcaatatca tgcgcccaat ctaatgctgt atttcctcca cctgatatta
    35161 atacatcttt atctttgaaa cgtctgtaac tttgtacaac ataatgtaaa ttagttaatt
    35221 gatatctctc tacaccttta acatctaatt gttttggatt aataataccc gcaccaattg
    35281 caatgataac tgctttcgat gtatatattt ctcccgcttc tgtttcaact tcgaaatgac
    35341 gttctgcctt tttcctaata tctaccacac gttcattcaa atgaacttcc ggtttaaaat
    35401 ataatccttg cttaattgta tcttttaaaa tttcatgaca aggttttggc gcaatgccgc
    35461 caatatccca aataattttt tcagggtaaa ttctcatctt accccctaat tcagattgaa
    35521 catctatcaa tcttacagac atatctcgca atccagcata aaagcttgca tacaaaccag
    35581 acggaccgcc accaatgatt gtaacatctt tcattatgtg cctcctatga ctctctatat
    35641 tcatttcttt cattaacgtg ctcaaattga taattattat catttaaagc cattatacta
    35701 ttaatattta tattgttaaa ataaatcgca tagttaatca tgaattatca ataactatcc
    35761 catcacaata taaaaacaca cctttcaaag taagaaacaa caatgttcct ttgaaagatg
    35821 tgtatatttt ttagttctag ttatattatt ttttaaaaga ctcatcacgt ggttctttaa
    35881 gaattgcttg tcttaaaagg aaaaatagca acaataaacc tgcaagcata cctgtgtgcc
    35941 caatacctgc aaagcctgca aatgcttctg gagagtatga tttaccagtg acttggaaga
    36001 atccttttgt caccatcata cctatagtaa cgataacacc tatgttatat acatagaaga
    36061 accagttaaa taagtagtaa cttgataatt taaataactt ctccaatggt aataatatta
    36121 aaaacataaa catacctaaa ataagtgtat gtgtgtgtac aagtgataat tgtgttgtac
    36181 cagtaaaatc atatgctttt gttagctctc tatagaaaaa gccactaaat aaacctatga
    36241 tcatataaaa aagaaatgaa tataataacc tacgcatttt gaatcctccc tcaccttttc
    36301 attatatccg attataccta ttataacagt gacaaaaaag cgaagatatg acacaactga
    36361 atttggttta gcacatagta tgacagctaa aataacttta catcaagcgc tatacaaata
    36421 aaatagctat accatgacgc tcgctacaaa cgtcttgtat agctattatt tctatttatt
    36481 aaattatgac ggcacttcag tacgttttgt gctatgtttt ctaacaatag ctgaaactaa
    36541 acttgataca gcgccaaaaa tcataaaccc tataaacatc cacattgtac tatttaattc
    36601 aatatgatga ttcaagtata atagttctct tacacttgtt gcatagtgtg tgaatggatt
    36661 ccaatcatat acatattttt gataactttc aggcaacatt tgtttaggta acgttacaag
    36721 ttgcatacta aagaacatta aaatgaagaa aattggaact gacttcatac ctagccatac
    36781 cataacacct aaaataaggc ccacgaaacc aagaatcgca aatgctacaa aaattgcgat
    36841 acgatttgga tggtcaaaat caaatccttg aacgccttgc atgaaataaa tataaacaaa
    36901 gctacctgca aatgctgcaa caactgcaaa tatcatctgt ccaattgaag caatgatacg
    36961 atgttgcacg acgatattgt tactagttct aaatgcaaag aacaataaga tagacgttac
    37021 gattgaacct atccaaattg gcataaacat taggaatggt gcattaccac ctgcttggtg
    37081 atctttaact ttattaagtt tttcattatc cacttttact ggattcgtca aaccattgat
    37141 gtccgcggca ttgactttaa cattttgact cgttaatgtt tccaaacttt gcttcgtaat
    37201 ttgagcatta atattatcac ccataccagt taacacagct gatgcaattt gtgaaccttg
    37261 taagcttgat ccttcactta caatcgtttt aaatttagcc tgcttaacct ctacttgttg
    37321 attccccatt ttttgtttca tttgttgaac cacttgtggc ggaatttcac ctgaagcaac
    37381 tttttgttgc atttcttctt ttttactatc cataactact ttttgtgttt tactcatagc
    37441 atcttttgaa aagtctttat caataatagc tactccaaag attttttgat ctttcaaatc
    37501 tttttcaagg tctttttcac tatcaacctt aacccattta attttattag aatcactatc
    37561 taataattta tcctctaatt ttttaccaat gttaacattt ttatcttgaa tcgttgtacc
    37621 tttatcctcg tttaatatac caattggtaa atcttttggt ttaggattat atgcaggata
    37681 aaaagctaaa gaaaagatta ccaagataat catagttgct attggcgcaa tccataataa
    37741 tttattttta aatatattca ttttattaat tacctcctta ttagacaatg tgttgaatat
    37801 ttcgcatgtt gtctattata atatgtaagt gggaataaac aatacacaat gttcatcaat
    37861 acgttcatta atagacaaat acacccacat tgttcaataa cacaaggagg ttgatttatt
    37921 tttgaaagaa gataggcgaa ttagaaagac aaagtcctcc attaaacaag cgttcactaa
    37981 attactacaa gaaaaagatt tagaaaagat taccattcgc gacataacaa cacgcgctga
    38041 tatcaataga gggacatttt acttacatta cgaggataaa tatatgttac tcgcagatat
    38101 ggaagatgag tatatttcag aactaacgac atatactcaa tttgatttgt tacgcggttc
    38161 ttcaattgaa gacattgcga atacttttgt aaataatata ctcaaaaata ttttccaaca
    38221 tattcatgat aatttagagt tttatcatac tattttacaa ttggaacgca cgagtcaatt
    38281 agaattgaaa atcaacgaac atatcaaaaa taatatgcaa cgttatatta gtatcaatca
    38341 ttctatcgga ggcgttccag agatgtattt ttacagttac gtttccggag caacaatttc
    38401 aattattaaa tactgggtaa tggacaaaca gcccatttca gttgatgaat tagctaaaca
    38461 tgtgcataat attattttta atggtccatt aagaataatg gcagaaaacc gtttgcataa
    38521 atcaaacctt gattcactaa cttaagtaat actcgctttt cctaaatcct ttagaaagga
    38581 actatatatc atgattactt cattcagaca ttctgaagat atagataaac atattataaa
    38641 aacaccatta gatcatacag cgtcatggat taatgtagta gaaccagacc gagaagaaat
    38701 tgaaaatctt atggaacaat ataatatacc tgaagacttt atacgtgacc ctttggactc
    38761 agaagaaagt tcccgtattg aatatgacga agatactggt tactcattaa tcattattga
    38821 tttacctatc gtcaattcaa ctaatcgtag cgttctatct tttgtaacga ttccattagg
    38881 cattattatt ggcaacggta ttatcgtaac agtttgtgac gctgaaaatg aatttttaga
    38941 aaatttacct aagcgtgata ttaatttaaa atttcacagc agatttgcat tagaaatttt
    39001 aactactatt gccgaccatt ataatcgtaa cttacgatta cttaataaaa gtagaattcg
    39061 tattgagaaa gaactaaaaa ataacattac taacaaacaa cttttcaaat taatggaagt
    39121 tgaaaaaagt ttagtatact ttttagctgc cttaaaaggt aacgatacaa ttattaaaaa
    39181 gttattccgt ttacctgcaa ttaaacgttt tgaagaagat gaagaattac tagaagattt
    39241 aatcattgaa aataaccaag ccatcgaaac aacagaatta catcaacgta tcttagaaag
    39301 tatcacaaca tcatacgctt ccttattatc taatgatatg aatacgatta tgaagacatt
    39361 aacacttttc acggtactat taacgttacc aacgctcgta tttagtttct tcggtatgaa
    39421 tgtgccgttg ccaattgatg accatagtta tatatcttgg attattgtgg taggtatttc
    39481 attaattctt gtcgtaattg ttagtatttt cttatggcgt aaacagaaat tataactaaa
    39541 ttaaaaggta tgacagctta aagtttcatc ctattgcatt tgcaatgact gatactttga
    39601 ttactgtcat acctcttttt tattctacaa cttctttatt tgcttttctt ttagataaaa
    39661 ttaaagtaac tgttatagca atgatgaatg atattgtcat accaacaaag tagtgtaacc
    39721 atcctgcatg tactggattg attgaaataa atcctggcaa tccagcagtt cctaatgcga
    39781 ttgctttaac cttgaagaaa gcaatatatg ctgaaccaat acctgatcca acgatagcgc
    39841 caataaatgg atatcttagt tttaagttaa caccaaacat agccggttct gtaataccaa
    39901 gtaatgctga aatacctgcg gcagatgcca caccttttaa cttcttattt tgtttaataa
    39961 taaagaacgc tgcaattgct gcaccacctt gtgcaacatt agacattgtc gcaatcggga
    40021 atataaatga tccacccgtt ttagtggcat ctgcaattaa tgtcgtttct acagctataa
    40081 agctatgatg catacctgta ataacaatcg gagcatacaa taatccgaat attaatccac
    40141 caattgcacc accaaattca taaagccatg ttaaaccatc tgataaccag taacctaatt
    40201 gtcgagtgat tggacctaca aatgaaaatg ttagaaatgc tgttataaaa atagataaca
    40261 atggtgttaa caaattatct aacaccgttg gaataacttt gcgtaaccct ttttcaattg
    40321 aggctaagat ataagctgct acaagcatag gtaacacttg tccttgataa cctacttgat
    40381 taatatgcaa accaaaaaca tcccaatatg gaatagcctt acctgcttca actgcttttg
    40441 ggaaatcgta tgcgctcatt agcgatggat gaactagtat catacctaat acagcaccta
    40501 aaaatggatt gccaccaaag cgttttgctg cactaaatcc aattaaaatt ggtaataatg
    40561 taaatggtgc attcgcaaaa acatttatca tttcagctaa tccagcaaat tgactatata
    40621 catctatcaa tgatttacct gaaaagaata aatctttcgc agtcaaaatg ttatttaacc
    40681 ccattaataa accaccagca acgatggctg gtataatcgg aacaaagata tctgaaagca
    40741 tttttacaaa tcgctgtaac ggattcatat ttttagcaga ttgtgctttg acttccgaag
    40801 tggttgatgc ttcttttcca gttaattttt ccagttcact aaatacttta ttgactgtac
    40861 cagacccaat aataatttgg tattgtcccc cagtagaaaa cgtcccttta actacatcca
    40921 taatgtttag cgcctcttca tttactaaac tttcatcatt taaaactaat cgtagtctcg
    40981 ttgcacaatg cgccattgca tctaaattct cttctccgcc tatcgcgttc aaaatatctt
    41041 ctgcggattg cttataattc atatatttag cctcctaatt agaaccggtt ccatttattc
    41101 cactttattg taaccggttc caaaaatatt tgcaacactc tattatcatt ttatataaac
    41161 acctacacca tttttgatag cgcattcatt tttattgcta tactatatgc atgtatatta
    41221 acattaatta tcggaggtaa ttttatgaaa gaacgtggcc atatcgaaca gctttggcgt
    41281 gaggaaaaat atcatgtatt gttacacagt caacagtctt accaaatgat aaggaatgct
    41341 ttaaaaacgg atttatcact tcatcaagtc caacaaatga ttgatgatgc tttgttaatt
    41401 gaaccgagta taggaagtgt atgtaatgct tttgatcata tgtggggata ttttaaaaaa
    41461 tgtgcgaatg aagaagaaag aaaacaatca aaactactta aagctgattt tattaatggt
    41521 aaaatcgaca cccaaacttt attagatttt ttagcagaac ttgctaataa atatgatgtt
    41581 caatatttac tacaaagtcg tgttttaaac acaaaaagaa agagatagat tgaaacttta
    41641 gttgtaacgg acaaatagta gtcattggag ttcagcaatt catactttgt actaaagttt
    41701 actataatct atctctcaag gtttaaatgt acatatctat attaagatgc gtttcatgat
    41761 gttagaagat accatacaca tttaattagt tacagcataa atcaatttat acccttaatt
    41821 attacattgt ttatatttta aattcggggg agtaatttta agtaatatct tgttgctgct
    41881 aattctattg ttaataaatt gatattagat gtagaaattg agtgtgaaag ttaataatag
    41941 atgatttagc tagtaacata attaattcat atatagtcaa aaagttctgt tagatactgt
    42001 tcttgatgaa tattctttga tgttaggtgt tagctattct agatgagttt cttagatgtg
    42061 gatgcctgtc ttgatgaagt tatctatgat gttaatataa tacttgatgt tgattcttag
    42121 atgttagtgc gatttcaaga tgctgattct ttgttgttgc actatcttgg tgacgtttct
    42181 agttgtttat agttatcgca tctcttgatg taaaatctaa gatgtttatg catttctaga
    42241 tgttaattct tcgctgctta agaattatct tgatggtaaa tctagttgtg ccatgcattt
    42301 tctcatgatg aatctaaggt gttaattcat tgatgtgtgc tgtttcttgt tgcttcatta
    42361 tcttgatggt gaatttcgtt gtctaatgca ctttttcaaa tgattattct aattgttacg
    42421 gcaataacta gatggatttt cttagatgtt cacttttcta gatgtttata cttatcttga
    42481 tgttttctaa acagaacttt taaacgcttt attttttagt agattgttta aaatttctta
    42541 gttgatggtt attgttgttg atttgaataa tttgtagcga atattttgta acagggctac
    42601 taagaatttt tataacaaga agtgatttca atcgtactaa ttttcagcgt ttgatgacaa
    42661 aagtgtatgt ccaaacttaa ataatggcga taaaatttaa gtcatgggta catttaatgt
    42721 tttttgattc aaacttccat tttggtcaat ttgctttttt tataacatag ttgaatatca
    42781 ataaaagatt agcaagttag ttcaaaatgg ctatgtattg ttttttgaaa tacataggtt
    42841 tgaaatctat attaattatg caccaaataa tttaattaga ctctatcgaa aatttccaaa
    42901 ttttgcttac tatctttcta attttacttt tatattgtgc acaatgcata aaaacaagcg
    42961 ttttcctagg agttttcatt aatttctttt atttttcact attacctttt caaaaatatt
    43021 caactataat aggtatacta tccatgattt taaaaatttc catgttttac atttaaatga
    43081 tagatttcaa tatatattag gcaggagaga gaaatatgac attccaactt aaaatacatc
    43141 atacattatc gacaatacca agtcgtaata ttaataatat t
//
LOCUS       DAPDIM010000016        42583 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000016 DAPDIM010000000
VERSION     DAPDIM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 42583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42583
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.016"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            52..1425
                     /locus_tag="RFE25_000943"
     CDS             52..1425
                     /locus_tag="RFE25_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HDU2816032.1"
                     /translation="MAIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSA
                     SDLKAQFYRGTLQRFYQSLHAEKLTPYVMSYDDIISFCKENNISEVVIAGDIMSYHLE
                     EYDILHQRSLFNEARIAVTLIRGNHYFKASKTMNQQGEPYKVFTSFYRKWRPYLRHRD
                     VYHYDLKSFEDFVIASPDDLVFDDIAFGSSQVIEQNKWQHFLDQDIQNYESGRDYLPE
                     VLTSQLSVALAYGLLDIIEIFNDLLARYDEDEANHEAFIRELIFREFYYVLMTQYPET
                     SYQAFKPKYRQIKWSQNEANFNAWCEGQTGFPIIDAAIMELTQTGFMHNRMRMVVSQF
                     LTKDLFIDWTWGEKFFRKHLIDYDAASNIHGWQWSASTGTDAVPYFRMFNPIRQSERF
                     DAKALYIKTYLPIFNQIDAKYLHDTQRNESNLFEQGIELGSHYPRQMVDHQEKRTQVL
                     ATFKALD"
     gene            complement(1580..1864)
                     /locus_tag="RFE25_000944"
     CDS             complement(1580..1864)
                     /locus_tag="RFE25_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816033.1"
                     /translation="MTINIIVLIVSIIVFQLIIGHIWHDIGLSYLRSILLMMLPFGLG
                     VFIQQVSYYERQYPKWQVPQNIKVRLKYIYLATFLEYVVLYLTLFTDILR"
     gene            complement(1861..2478)
                     /locus_tag="RFE25_000945"
     CDS             complement(1861..2478)
                     /locus_tag="RFE25_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1361 domain-containing protein"
                     /protein_id="HDU2816034.1"
                     /translation="MQSRYIARIYFLILFIVSLFETKIFQFMTLNLFLAYIPFELSLL
                     LRLFKPNKKYEWPLFIIYSFIFVLLLPNTFYMVTDLIHLNQFQFNFYAGLNLSEWKYF
                     TYLLLGVFLAVYVMILIYFEILTLTSHRWLNRLIVVVLMFLNGFGIYIGRFLRLHSVY
                     FFNEPLHVLNHILESLTLKTAMFVCFMVVMQAAILLFGKGVRLNK"
     gene            complement(2664..3086)
                     /locus_tag="RFE25_000946"
     CDS             complement(2664..3086)
                     /locus_tag="RFE25_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDU2816035.1"
                     /translation="MKLQKSNHTILLVLEKGEDIVECITTFADDQDLTFTSVSGIGAC
                     DDVVLKFFNLTTKQYEEKHITEPLELTSLLGNISRLDNGHFAHLHATFGTQSYETFSG
                     HLAKAIVSATAEIILTVTDLDIQRSFKDAVGLNLLDPQ"
     gene            3295..4461
                     /gene="norA"
                     /locus_tag="RFE25_000947"
     CDS             3295..4461
                     /gene="norA"
                     /locus_tag="RFE25_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter NorA"
                     /protein_id="HDU2816036.1"
                     /translation="MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLV
                     AAFALSQMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGG
                     MSAGMVMPGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIGGFMAEVSHRMPFY
                     FAGALGILAFIMSIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGL
                     SAFETLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSL
                     LYSVVVLILLVFANGYWSIMLISFVVFIGFDMIRPAITNYFSNIAGERQGFAGGLNST
                     FTSMGNFIGPLIAGALFDVHIEAPIYMAIGVSLAGVVIVLIEKQHRAKLKEQNM"
     gene            4754..5206
                     /locus_tag="RFE25_000948"
     CDS             4754..5206
                     /locus_tag="RFE25_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816037.1"
                     /translation="MTVKNLFLGFVAVILTVCLIGLLILATNEDALAKVHKTINTLNA
                     INVSTEDTYKKKMDILNIHTAKASEVNENVEKQNHFKHRVNANKSNSFNEQECQVIAD
                     RYADKHINDNYGLERISKTNHGYNYVYSNDNSTSKQHVSISNQGIITK"
     gene            5380..5775
                     /locus_tag="RFE25_000949"
     CDS             5380..5775
                     /locus_tag="RFE25_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDU2816038.1"
                     /translation="MAKNKKTNAMRMLDRAKIKYEVHSFEVPEEHLSGAEVAELIQAN
                     VKTVFKTLVLENTKHEHFVFVIPVSETLDMKKAAALVGEKKLQLMPLDNLKNVTGYIR
                     GGLRTMQITIAVEDLITITKGKIGAVIHE"
     gene            6025..6789
                     /locus_tag="RFE25_000950"
     CDS             6025..6789
                     /locus_tag="RFE25_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDU2816039.1"
                     /translation="MMIITEKRHELILEELSHKDFLTLQELIDRTGCSASTIRRDLSK
                     LQQLGKLQRVHGGAMLKENRMIEANLTEKLATNLDEKKMIAKIAANQINDNECLFIDA
                     GSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEI
                     LRRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTAMSLANQSFVLIDHSKFNKVYFA
                     RVPLLESTTIITSEKALNQESLKEYQQKYHFIGGTL"
     gene            6786..7706
                     /gene="pfkB"
                     /locus_tag="RFE25_000951"
     CDS             6786..7706
                     /gene="pfkB"
                     /locus_tag="RFE25_000951"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDU2816040.1"
                     /translation="MIYTVTFNPSIDYVIFTNDFKIDGLNRATATYKFAGGKGINVSR
                     VLKTLDVESTALGFAGGFPGKFIIDTLNNSAIQSNFIEVDEDTRINVKLKTGQETEIN
                     APGPHITSTQFEQLLQQIKNTTSEDIVIVAGSVPSSIPSDAYAQIAQITAQTGAKLVV
                     DAEKELAESVLPFHPLFIKPNKDELEVMFNTTVNSDTDVIKYGRLLVDKGAQSVIVSL
                     GGDGAIYIDKEISIKAVNPQGKVVNTVGSGDSTVAGMVAGIASGLTIEKAFQQAVACG
                     TATAFDEDLATRDAIEKIKSQVTISVLDGE"
     gene            7712..9670
                     /locus_tag="RFE25_000952"
     CDS             7712..9670
                     /locus_tag="RFE25_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDU2816041.1"
                     /translation="MRVTELLTKDTIAMDLMANDKNGVIDELVNQLDKAGKLSDVASF
                     KEAIHNRESQSTTGIGEGIAIPHAKVAAVKSPAIAFGKSKEGVDYQSLDMQPAHLFFM
                     IAAPEGGAQTHLDALAKLSGILMDENVREKLLHASSPEEVLAIIDEADDEVTKEEEAE
                     AEAQQVATAEQSSKQSNEPYVLAVTACPTGIAHTYMARDALKKQADKMGIKIKVETNG
                     SSGIKNHLTEQDIENATGIIVAADVHVETDRFDGKNVVEVPVADGIKRPEELINKALD
                     TSRKPFVARDGQRKGNSNDSQEKLSPGKAFYKHLMNGVSNMLPLVISGGILMAIVFLF
                     GANSFNPKSSEYNAFAEQLWNIGSKSAFALIIPILSGFIARSIADKPGFASGLVGGML
                     AISGGSGFIGGIIAGFLAGYLTQGVKAMTRKLPQALEGLKPTLIYPLLTVTATGLLMI
                     YVFNPPASWLNHLLLDGLNNLSGSNIVLLGLVIGAMMAIDMGGPFNKAAYVFATGALI
                     EGNAAPITAAMIGGMIPPLAIATAMLIFRRKFTKEQRGSIIPNYVMGMSFITEGAIPF
                     AAADPLRVIPSMMIGSGIGGAIALGLGSRITAPHGGIIVIVGTDGAHLLQTLIALLVG
                     TLVSALIYGLIKPKLTETEIEASKSMDE"
     gene            9978..11159
                     /gene="nagA"
                     /locus_tag="RFE25_000953"
     CDS             9978..11159
                     /gene="nagA"
                     /locus_tag="RFE25_000953"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDU2816042.1"
                     /translation="MSELIIYNGKVYTEDGKIDNGYIHVKDGQIVAIGEGDDKAAIDN
                     DTTNKIQVIDAKGHHVLPGFIDIHIHGGYGQDAMDGSYDGLKYLSENLLSEGTTSYLA
                     TTMTQSTDKIDKALTNIAKYEAEQDVHNAAEIVGIHLEGPFISENKVGAQHPQYVVRP
                     FIDKIKHFQETANRLIKIMTFAPEVEGAKEALETYKDDIIFSIGHTVATYEEAVEAVE
                     RGAKHVTHLYNAATPFQHREPGVFGAAWLNDALHTEMIVDGTHSHPASVAIAYRMKGN
                     ERFYLITDAMRAKGMPEGEYDLGGQKVTVQSQQARLANGALAGSILKMNHGLRNLISF
                     TGDTLDHLWRVTSLNQAIALGIDDRKGSIKVNKDADLVILDDDMNVKSTIKQGKVHTF
                     S"
     gene            11380..12729
                     /locus_tag="RFE25_000954"
     CDS             11380..12729
                     /locus_tag="RFE25_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDU2816043.1"
                     /translation="METSTIISLIIFILLIALTTVFVGSEFALVKIRATRIEQLADEG
                     NKPAKIVKKMIANLDYYLSACQLGITVTSLGLGWLGEPTFEKLLHPIFEAINLPTALT
                     TTISFAVSFIIVTYLHVVLGELAPKSIAIQHTEKLALVYARPLFYFGNIMKPLIWLMN
                     GSARVIIRMFGVNPDAQTDAMSEEEIKIIINNSYNGGEINQTELAYMQNIFSFDERHA
                     KDIMVPRTQMITLNEPFNVDELLETIKEHQFTRYPITDDGDKDHIKGFINVKEFLTEY
                     ASGKTIKIANYIHELPMISETTRISDALIRMQREHVHMSLIIDEYGGTAGILTMEDIL
                     EEIVGEIRDEFDDDEVNDIVKIDNKTFQVNGRVLLDDLTEEFGIEFDDSEDIDTIGGW
                     LQSRNTNLQKDDYVDTTYDRWVVSEIDNHQIIWVILNYEFNEARPTIGQSDEDEKSE"
     gene            12951..13790
                     /locus_tag="RFE25_000955"
     CDS             12951..13790
                     /locus_tag="RFE25_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDU2816044.1"
                     /translation="MLNEIQILNNGYPMPSVGLGVYKISDEDMTKVVNAAIDAGYRAF
                     DTAYFYDNEASLGRALKDNGVDREDLFITTKLWNDYQGYEKTFEYFNKSIENLQTDYL
                     DLFLIHWPCEADGLFLETYKAMEELYEQGKVKAIGVCNFNVHHLEKLMAQSSIKPMVN
                     QIEVHPYFNQQELQEFCDRHDIKVTAWMPLMRNRGLLDNPVIVKIAEKYHKTPAQVVL
                     RWHLAHNRIIIPKSQTPKRIQENIDILDFNLELTEVAEIDALDRNARQGKNPDDVKIG
                     DLK"
     gene            13922..14905
                     /gene="csbB"
                     /locus_tag="RFE25_000956"
     CDS             13922..14905
                     /gene="csbB"
                     /locus_tag="RFE25_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoteichoic acid-specific glycosylation protein
                     CsbB"
                     /protein_id="HDU2816045.1"
                     /translation="MKIRVVIPCFNEGEVITQTHQQLTEILSQDSSVKGYDYNMLFID
                     DGSTDTTIDEMQHLATIDRHVSFISFSRNFGKEAAMIAGYQHSTEFDAVIMIDCDLQH
                     PPEYIPKMVEGFMEGYDQVIAKRDRSGENFSRKTLSHLYYKLVNCFVEEVQFDDGVGD
                     FRLLSQRAVKSIASLEEYNRFSKGLFEWIGYNTKVFTYQNVERQKGESKWSFKKLFNY
                     GIDGLISFNSKPLRMMIYLGLFIFSISVLYIIYLFINIMISGVNIPGYFSTIAAILLL
                     GGIQLISIGVVGEYIGRIYYEVKARPKYIIQATNLSSIENDEKDTHKVYSK"
     gene            complement(14977..16032)
                     /gene="saeS"
                     /locus_tag="RFE25_000957"
     CDS             complement(14977..16032)
                     /gene="saeS"
                     /locus_tag="RFE25_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     SaeS"
                     /protein_id="HDU2816046.1"
                     /translation="MVLSIRSQIIIGVVSSILLTSTILAIAYILMWFNGHMTLTLTLT
                     TIITSCLTLLICSIFINPLIQKIKQFNIKTKQFANGNYASNDKTFNSPKEIYELNQSF
                     NKMASEITQQMNQIKSEQQEKTELIQNLAHDLKTPLASIISYSEGLRDGIITKDHEIK
                     ESYDILIKQANRLSTLFDDMTHIITLNTGKTYPPELIQLDQLLVSILQPYEQRIKHEN
                     RTLEVNFCSEIDAFYQYRTPLERILTNLLDNALKFSNVGSRIDINISENKDQDTIDIA
                     ISDEGIGIIPELQERIFERTFRVENSRNTKTGGSGLGLYIANELAQQNNAKISVSSDI
                     DVGTTMTVTLHKLDITS"
     gene            complement(16032..16718)
                     /locus_tag="RFE25_000958"
     CDS             complement(16032..16718)
                     /locus_tag="RFE25_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2816047.1"
                     /translation="MTHLLIVDDEQDIVDICQTYFEYEGYKVTTTTSGKEAISLLSND
                     IDIMVLDIMMPEVNGYDIVKEMKRQKLDIPFIYLTAKTQEHDTIYALTLGADDYVKKP
                     FSPRELVLRINNLLTRMKKYHHQPVEQLSFDELTLINLSKVVTVNGHEVPMRIKEFEL
                     LWYLASRENEVISKSELLEKVWGYDYYEDANTVNVHIHRIREKLEKESFTTYTITTVW
                     GLGYKFERSR"
     gene            complement(16693..17166)
                     /locus_tag="RFE25_000959"
     CDS             complement(16693..17166)
                     /locus_tag="RFE25_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDU2816048.1"
                     /translation="MNKLLLLVTFIIRVGSGIVMLMQGYEKLTGGFTLKGLVPVIANN
                     TDSPEWYKWFFANIVAHTTSLFDIVVPLGEIAIGLGLIFGVFAYAASFFGAFVMINYI
                     LADMIFTYPLQLTFFILLLMSHSLLKQISLKEIINYFRGRKNRGEKIDDPLTDRG"
     gene            complement(17509..17949)
                     /locus_tag="RFE25_000960"
     CDS             complement(17509..17949)
                     /locus_tag="RFE25_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DM13 domain-containing protein"
                     /protein_id="HDU2816049.1"
                     /translation="MNTKYFLAVGAVASVLTLGACGNSNSQDQGNKTEQKTKSEDSNV
                     KTDKTKHLTGTFSSKNGETVEGKAEIKNGKLMLTNYKSSKGPDLYVYLTKNGDIKNGK
                     EIAMVDYDKEKQTFDLKNVDLSKYDEVTIYCKKAHVIFGGAKLK"
     gene            complement(18229..18813)
                     /locus_tag="RFE25_000961"
     CDS             complement(18229..18813)
                     /locus_tag="RFE25_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816050.1"
                     /translation="MILYILINIAIVVLITGFNLYRHQMQHLSLSAMLLSITINAFIN
                     TFIIDKYNFITLCTITMFIIWTILQFYIDKKLKPVYITDQKFIAIILTIVVSLTQRVT
                     DFSSTQSIYMSIPFLAPAIFIIGGIMLFISTFNSLDETAENNNKIKKLMIKGLIIINI
                     SFIVMMVLTPYWYLYLIVYLIFLLFLLWQKVYKF"
     gene            complement(18912..19625)
                     /gene="queE"
                     /locus_tag="RFE25_000962"
     CDS             complement(18912..19625)
                     /gene="queE"
                     /locus_tag="RFE25_000962"
                     /EC_number="4.3.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HDU2816051.1"
                     /translation="MAKIPVLEIFGPTIQGEGRVIGRKTMFVRTAGCDYRCSWCDSAF
                     TWDGSAKGDIKLMTAEEIYDELKRIGGDLFNHVTISGGNPALIKGIQELVDLFQDKGI
                     FSALETQGSKFQPWMTQIDDLTISPKPPSSTMTPDLKKLDEVITQCVPSSLNLKVVVF
                     DDKDYDFAKMIHHRYPDIPFYLQVGNPYLSDSVDNHTEKLLERYEQLVDLVMQSNDMN
                     HVYVLPQLHTLLWSNKKGV"
     gene            complement(19629..20048)
                     /gene="queD"
                     /locus_tag="RFE25_000963"
     CDS             complement(19629..20048)
                     /gene="queD"
                     /locus_tag="RFE25_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HDU2816052.1"
                     /translation="MLQQIYPSTTHPYQFELNKDFNFSAAHHIPCEEAGICQNVHGHT
                     YFVNLTIVGDKLDDTGFLVNFSHLKKMIHGKFDHQLLNNLPAFKNKIPSTEIVAETIY
                     QIVKENLASLEHQPKCIQVFVRETPTSYVVFRPKEQV"
     gene            complement(20050..20718)
                     /gene="queC"
                     /locus_tag="RFE25_000964"
     CDS             complement(20050..20718)
                     /gene="queC"
                     /locus_tag="RFE25_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HDU2816053.1"
                     /translation="MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQR
                     HDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARN
                     LLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHT
                     PLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLES
                     KGAL"
     gene            21069..21662
                     /locus_tag="RFE25_000965"
     CDS             21069..21662
                     /locus_tag="RFE25_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDU2816054.1"
                     /translation="MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMK
                     PKAIVISPGPGNPDDYPILNEVLEQFYQRVPILGVCLGFQCIVSYFGGNIIHGYHPVH
                     GHTTQLRHTNEGIFQGLPQNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHIR
                     FPVFGVQYHPESILSEYGYRQVELFLSKVGDYCENRI"
     gene            21646..22797
                     /locus_tag="RFE25_000966"
     CDS             21646..22797
                     /locus_tag="RFE25_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I family
                     protein"
                     /protein_id="HDU2816055.1"
                     /translation="MRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHF
                     AQAQQRQGRYVSLYLSYEAAKYFNHVMCTHSLAKDDIYAVAYSFEKAESINSTYEHQT
                     SYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLT
                     QFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQ
                     QYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVS
                     GTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQFESSPRGIYCGAIGLLLPTEDD
                     KMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML"
     gene            22797..23405
                     /locus_tag="RFE25_000967"
     CDS             22797..23405
                     /locus_tag="RFE25_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HDU2816056.1"
                     /translation="MQLFETMKIDNGYIPRLTYHTNRIKCSSERLNFKFDEHAWRNEL
                     NDVTTKYHSGQYRLKIVLNAESKFETIVSPLPEKSSFTAKFQVLPKVVNPTFIKNKTT
                     ERKHLAHNHETDLILLTSEDGKVLEFDIGNIVIEEDGKWYTPSYKDDFLKGCMRDYLI
                     DSDKLVEKDFNKNELIYKYHNNEIRLFLINSLREVADVHLCL"
     gene            23471..23677
                     /locus_tag="RFE25_000968"
     CDS             23471..23677
                     /locus_tag="RFE25_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816057.1"
                     /translation="MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIVTITTVISF
                     ILVYALIHELMPFVVRAMDLMYHQ"
     gene            23765..24475
                     /locus_tag="RFE25_000969"
     CDS             23765..24475
                     /locus_tag="RFE25_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allophanate hydrolase subunit 1"
                     /protein_id="HDU2816058.1"
                     /translation="MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIE
                     IVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYG
                     SKYGPDIESLLKHYKIKLETFIELHSKTQYFVSMMGYSPGFPYLTGLNKKLYINHTSK
                     QKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFR
                     PINENELEVGAFKDVNHN"
     gene            24459..25463
                     /locus_tag="RFE25_000970"
     CDS             24459..25463
                     /locus_tag="RFE25_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HDU2816059.1"
                     /translation="MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRL
                     VANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLK
                     FRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTAR
                     HHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKV
                     TSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQI
                     GTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
                     "
     gene            25937..27877
                     /gene="ltaS"
                     /locus_tag="RFE25_000971"
     CDS             25937..27877
                     /gene="ltaS"
                     /locus_tag="RFE25_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyglycerol-phosphate lipoteichoic acid
                     synthase LtaS"
                     /protein_id="HDU2816060.1"
                     /translation="MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNL
                     ILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFST
                     LNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMA
                     ASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALAS
                     EDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLN
                     KLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAI
                     LDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFF
                     KDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDE
                     ALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGF
                     WIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGD
                     FITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNP
                     DFKKVNPSKYKYETGPKANSKK"
     gene            28147..30030
                     /locus_tag="RFE25_000972"
     CDS             28147..30030
                     /locus_tag="RFE25_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDU2816061.1"
                     /translation="MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGK
                     STLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQ
                     YEQAVQAYADDQSDKLFKRMIDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKEL
                     SGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYF
                     LNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAG
                     AKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKV
                     LFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTD
                     ETLDRDIRMIDYLREESEVAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKR
                     LYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQS
                     YWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSYTTVRKKNGLSYKEKLEYE
                     QLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIK
                     EQQ"
     gene            30042..31823
                     /gene="recQ"
                     /locus_tag="RFE25_000973"
     CDS             30042..31823
                     /gene="recQ"
                     /locus_tag="RFE25_000973"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDU2816062.1"
                     /translation="MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSI
                     CYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSN
                     GEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFT
                     LPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFIL
                     DYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDR
                     VKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERD
                     INLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQC
                     SNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTH
                     GLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATE
                     KVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMIN
                     IDGVGSYKLKHYCPAFLETIQNYKAKV"
     gene            32045..33022
                     /locus_tag="RFE25_000974"
     CDS             32045..33022
                     /locus_tag="RFE25_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816063.1"
                     /translation="MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTL
                     KMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQM
                     KKWKEKDIDKRVDELLDMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMD
                     EPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQID
                     TPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYD
                     NQPIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD"
     gene            33015..34529
                     /locus_tag="RFE25_000975"
     CDS             33015..34529
                     /locus_tag="RFE25_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HDU2816064.1"
                     /translation="MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILL
                     TKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYT
                     GIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIG
                     AGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVM
                     IIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAF
                     LFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMK
                     YNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNL
                     DNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKE
                     SFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK"
     gene            34769..35827
                     /gene="hisC"
                     /locus_tag="RFE25_000976"
     CDS             34769..35827
                     /gene="hisC"
                     /locus_tag="RFE25_000976"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDU2816065.1"
                     /translation="MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSP
                     KVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLT
                     PGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPN
                     NPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRT
                     FSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHK
                     NSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIG
                     FKEQNDKMLEVLSNFKYE"
     gene            36166..36708
                     /locus_tag="RFE25_000977"
     CDS             36166..36708
                     /locus_tag="RFE25_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'(3')-deoxyribonucleotidase"
                     /protein_id="HDU2816066.1"
                     /translation="MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLK
                     HVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDK
                     YEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDR
                     FERVNSWKDVEQYFLDNIEK"
     gene            complement(37587..38504)
                     /locus_tag="RFE25_000978"
     CDS             complement(37587..38504)
                     /locus_tag="RFE25_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDU2816067.1"
                     /translation="MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLS
                     ENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTF
                     NDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGS
                     KDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTD
                     LSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKV
                     DIDGEISLETPIDIEVIPNAIQLLTVNDL"
     gene            38595..38696
                     /locus_tag="RFE25_000979"
     CDS             38595..38696
                     /locus_tag="RFE25_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816068.1"
                     /translation="MVITDIDVYRVGRENIVIAVYNEHIKLLFILIS"
     gene            complement(38774..40279)
                     /locus_tag="RFE25_000980"
     CDS             complement(38774..40279)
                     /locus_tag="RFE25_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDU2816069.1"
                     /translation="MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMR
                     ALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLG
                     AVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFV
                     IFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMK
                     PTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYF
                     TLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGW
                     KTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGI
                     VGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNA
                     SAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR"
     gene            complement(40620..41120)
                     /gene="queF"
                     /locus_tag="RFE25_000981"
     CDS             complement(40620..41120)
                     /gene="queF"
                     /locus_tag="RFE25_000981"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HDU2816070.1"
                     /translation="MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDY
                     FVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCM
                     NIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYP
                     EKIDNR"
     gene            complement(41140..42006)
                     /locus_tag="RFE25_000982"
     CDS             complement(41140..42006)
                     /locus_tag="RFE25_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001594836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDU2816071.1"
                     /translation="MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVA
                     MFIPLFFLYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLN
                     PFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAAS
                     AYTCVRALSSREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVG
                     QIGVTLAYSFAAAKDISIFTYASIIFTAILGFVLFGESPDFYATLGYVVIIGASYYMF
                     EKARRDAKIIKK"
BASE COUNT        15150 a         6059 c         7557 g        13817 t
ORIGIN      
        1 agtgacaaaa agcttaataa aataaaaaga taattgaagg gtgttttgtt tatggcaatt
       61 gctgtgttat taaatcgaat gtttcgaatg gaacacaatc cattatttga atatatttat
      121 caacaaaaag aagacattga tgcatgttat tttatcattc cggaagagga catgtcttca
      181 gcttctgatt tgaaagcaca gttttatcgc ggtactttgc agcgctttta ccaatcgttg
      241 cacgcagaaa agcttacacc ttatgttatg tcttatgacg atatcatttc attttgtaaa
      301 gagaacaata tctctgaagt agtgattgcg ggtgatatta tgagttatca tcttgaagaa
      361 tatgatattt tacatcaacg ttctttattc aatgaagcac gtattgccgt tactttaatt
      421 cgtgggaatc attactttaa agcgagtaaa acaatgaatc aacaagggga gccatacaaa
      481 gtttttacta gtttctatag aaaatggcga ccttacttga ggcatagaga cgtatatcac
      541 tatgatttaa aatcattcga agactttgtc attgcatcac ctgatgattt agtgtttgat
      601 gacatagcgt ttggatcctc acaagtaatt gaacagaata aatggcaaca ttttttagat
      661 caagatatac agaattacga aagcggaaga gactatttac ctgaagtgtt aacaagtcag
      721 ctaagtgttg ctttagcata tggattatta gatattattg aaatttttaa tgatttattg
      781 gcgcgttatg atgaagatga ggcaaaccat gaagcattta tacgtgaact catttttaga
      841 gaattttatt atgtgttaat gacacagtat ccagaaacct cataccaagc tttcaaacct
      901 aaatatcgac agataaaatg gtcgcaaaat gaagcgaatt ttaatgcatg gtgcgaaggg
      961 caaacaggat ttccaatcat tgatgcagca ataatggaat tgacacaaac tggttttatg
     1021 cataatcgaa tgagaatggt tgtgtcgcaa tttttaacca aagatttatt tatagattgg
     1081 acatggggag aaaaattctt tagaaagcac cttattgact atgatgcagc atcaaatatt
     1141 catggatggc aatggtctgc ttctacaggt acggatgcag tgccgtattt tagaatgttt
     1201 aatccaataa gacagagtga acgctttgat gctaaagctt tgtatatcaa aacatatctt
     1261 ccgattttta atcaaattga tgcaaaatat ttgcatgata cacaacgcaa tgagtccaac
     1321 ctttttgaac aggggattga attaggtagt cattatccaa gacaaatggt agatcatcaa
     1381 gaaaaacgta cacaagtttt agctacattt aaagcgctag actaattcgg ctcaattgat
     1441 agatctggca tgagtaaaat ctggagcaga atataaagtt cttaagcaat ataaataagc
     1501 caatttctat tattgatgtg atagaaattg gctttcctca aatatataag ttgtatttag
     1561 ttttcttatt aaattgatgt tatcttagta tgtccgtaaa taaagtgagg tatagtacga
     1621 catactctaa aaacgtagcg agataaatat atttcaatct aacttttatg ttttgaggca
     1681 cttgccattt aggatattgt cgttcgtaat acgacacttg ttgtataaat acacctagtc
     1741 caaatggcag catcatgagt aagatacttc ttaaataact taaaccaata tcatgccata
     1801 tgtgtccaat aatcaattga aagacaatga tagatactat taaaacgatt atatttattg
     1861 tcacttgttc aaacgcactc cttttccaaa taatagaatt gctgcttgca tgacaaccat
     1921 aaaacataca aacatagcag ttttaagcgt tagactttct agaatgtgat ttagaacatg
     1981 taagggctca ttaaagaaat aaacggaatg taagcgtaag aaacgaccaa tataaattcc
     2041 gaatccattt aaaaacatta gcacgacaac aattaatcta ttaagccaac ggtgagaagt
     2101 caatgttagt atttcaaaat agattaaaat catcacataa accgctaaga agacaccaag
     2161 cagtaaatag gtaaagtatt tccactcact taaatttagt cctgcgtaaa agttgaattg
     2221 aaattggttc aaatggatta aatcagttac catataaaat gtatttggta aaagtaacac
     2281 aaatataaaa ctatatatga taaagagtgg ccattcatac tttttattcg gtttgaataa
     2341 tcgtaataat agactaagct caaaaggtat atatgctaaa aacaaattta aagtcataaa
     2401 ttgaaaaatt ttagtctcaa aaagggagac gataaataaa attaaaaagt aaattctagc
     2461 gatgtatcga gattgcatca ataataaaca ctactttcta atgaaaaagt tattcattca
     2521 aatgtgatag ttataaacgc attcaattcc taattaaaaa tttaatttaa ctcgttgaag
     2581 tatattaata aacgagaatg catttatgat taagcactta tgataacttg taataaaatt
     2641 tgattcaact aaaaagtaaa gtgctattga ggatcaagta aatttaaacc gactgcatct
     2701 ttgaatgaac gttgaatgtc caaatcagtt acagtaagaa tgatttcagc agttgcagaa
     2761 acaattgctt tagcgagatg tccgctaaaa gtttcatatg attgagtacc gaaagtagca
     2821 tgcaaatgtg caaaatgacc attgtctaga cgagaaatat tacctaataa gctcgtcaat
     2881 tccagtggct cagtaatatg tttttcttcg tattgtttcg ttgttaaatt gaaaaatttt
     2941 aatacaacgt catcacatgc accaatgccg ctgacagatg taaatgttaa gtcttggtca
     3001 tctgcaaagg ttgttataca ttcaacgata tcttctcctt tttccaacac tagtagtata
     3061 gtatgattac ttttttgcaa tttcatatga tcaatcccct ttattttaat atgtcattaa
     3121 ttatacaatt aaatggaaaa tagtgataat tacaaagaaa aaatattgtc aaatgtagca
     3181 atgttgtaat acaatataga aactttttac gaatatttag catgaattgc aatctgtcgt
     3241 ggaaaagaag aataacagct ttaagcatga catggagaaa aaagaggtga gcatatgaat
     3301 aaacagattt ttgtcttata ttttaatatt ttcttgattt ttttaggtat cggtttagta
     3361 ataccagtct tgcctgttta tttaaaagat ttgggattaa ctggtagtga tttaggatta
     3421 ctagttgctg cttttgcgtt atctcaaatg attatatcgc cgtttggtgg tacgctagct
     3481 gacaaattag ggaagaaatt aattatatgt ataggattaa ttttgttttc agtgtcagaa
     3541 tttatgtttg cagttggcca caatttttcg gtattgatgt tatcgagagt gattggtggt
     3601 atgagtgctg gtatggtaat gcctggtgtg acaggtttaa tagctgacat ttcaccaagc
     3661 catcaaaaag caaaaaactt tggctacatg tcagcgatta tcaattctgg attcatttta
     3721 ggaccaggga ttggtggatt tatggcagaa gtttcacatc gtatgccatt ttactttgca
     3781 ggagcattag gtattctagc atttataatg tcaattgtat tgattcacga tccgaaaaag
     3841 tctacgacaa gtggtttcca aaagttagag ccacaattgc taacgaaaat taactggaaa
     3901 gtgtttatta caccagttat tttaacactt gtattatcgt ttggtttatc tgcatttgaa
     3961 acattgtatt cactatacac agctgacaag gtaaattatt cacctaaaga tatttcgatt
     4021 gctattacgg gtggcggtat atttggggca cttttccaaa tctatttctt cgataaattt
     4081 atgaagtatt tctcagagtt aacatttata gcttggtcat tattatattc agttgttgtc
     4141 ttaatattat tagtttttgc taatggctat tggtcaataa tgttaatcag ttttgttgtc
     4201 ttcataggtt ttgatatgat acgaccagcc attacaaatt atttttctaa tattgctgga
     4261 gaaaggcaag gctttgcagg cggattgaac tcgacattca ctagtatggg taatttcata
     4321 ggtcctttaa tcgcaggtgc gttatttgat gtacacattg aagcaccaat ttatatggct
     4381 ataggtgttt cattagcagg tgttgttatt gttttaattg aaaagcaaca tagagcaaaa
     4441 ttgaaagaac aaaatatgta gcataagtat tttggtgtat attgatataa agtaaagcgt
     4501 aatattatga atgattagca tcgtttttct tatgaatttt attaagaaaa ttcgatgctt
     4561 tacatttaaa aagattcgat tgactaaatg ttttactctt tatatttaaa tgttatatgt
     4621 aacaaaaaat gattttgagt aataaacatg ttacaaatat tacattcttt ttaaattgca
     4681 atccacatac ctaattcatt aacgttaatg tgttaagatg ataaaaaatg agtaaggaaa
     4741 tgtgggtaag gggatgacag taaaaaattt atttttaggc tttgttgctg taatattaac
     4801 cgtttgttta attggtttat taatattagc aacaaatgaa gatgcgcttg ctaaggtaca
     4861 taaaacaatt aatacgctta acgcgataaa tgtatcaact gaagatactt ataaaaagaa
     4921 aatggatatt ctcaatattc atactgctaa agcatctgaa gtgaatgaaa atgtggaaaa
     4981 gcaaaatcat tttaaacatc gtgtgaatgc aaataaatca aattctttta acgaacaaga
     5041 gtgccaagtt attgctgatc gttatgcaga taagcatatc aatgataatt atggtttaga
     5101 aagaatttct aagacaaatc atggatataa ttatgtttat tccaatgata attcaactag
     5161 taagcaacat gtaagtattt caaatcaagg cataataacg aaataataga tggaacagtg
     5221 tattctaatt ggatatactg tttttatttt gcaataattt aatttaaaaa ggtgaaatca
     5281 acttataaaa tgatgtaaat gttatgtcaa aatcaaccaa tccgtaatgt attttaaaat
     5341 gttaatatag ttctgaagaa gtataaatga ggtgttgaaa tggctaaaaa taagaaaacg
     5401 aacgcgatgc gtatgcttga tcgtgcaaaa attaaatacg aagttcatag ctttgaggta
     5461 ccagaagaac atttatcggg tgcagaagtc gcagaactta tacaagcaaa tgttaaaaca
     5521 gtatttaaaa cgcttgttct agaaaataca aaacatgaac attttgtatt tgttatccca
     5581 gtaagtgaaa ctttagatat gaaaaaggca gctgctttgg ttggagagaa gaaattgcag
     5641 cttatgcctt tagataattt gaaaaatgta acgggataca ttcgtggtgg gcttcgaaca
     5701 atgcaaatca caatagctgt tgaggatttg attacaataa ctaaaggcaa aattggagca
     5761 gttatccatg aatgattaat aacaacaaaa agtatggggc aagattagga gtgtggcaga
     5821 gatgaaattt ttataaaatt catttctgcc acactccttt ttgattgaat tagcatttta
     5881 cgatcataaa cagtcattat aattgagtat ttgaacataa aaatgtaatt ttatcgtcac
     5941 aatttgggtg tttgtgattg tttttggtaa tttatgattg aaaagtgaaa gcgtactcat
     6001 tataatacaa agtgagatgg ggtgatgatg ataattactg aaaaaagaca cgagttaata
     6061 ttagaagaac tttcgcacaa agattttttg actttacaag aattaataga tcgaactggt
     6121 tgcagtgctt caacaatacg aagagattta tctaaactac aacaattagg gaaattgcaa
     6181 cgtgtgcatg gtggtgcaat gttaaaagaa aatcgtatga ttgaggcgaa tttaactgaa
     6241 aaattagcaa cgaatcttga tgaaaagaaa atgattgcta aaatagcagc taatcaaatc
     6301 aacgataatg aatgcttatt tatcgatgct ggttcatcta cattggagct aattaaatat
     6361 attcaagcga aagatatcat tgtggtaacc aatggtttaa cacatgtaga agctttactt
     6421 aaaaaaggta ttaaaacaat tatgctaggt ggtcaagtta aagaaaatac acttgctacg
     6481 attggttcta gtgctatgga gatattaaga cgatattgtt tcgataaagc ttttatcggg
     6541 atgaatggat tagatattga acttggatta actactcccg atgagcaaga ggcattagtt
     6601 aaacaaacag caatgtcatt agccaatcaa tcatttgtac ttatagatca ttctaagttt
     6661 aataaagtat attttgctcg tgtacctttg ctagaaagta cgacaatcat cacatctgaa
     6721 aaagcattaa atcaagaatc gttaaaagaa taccaacaaa agtatcactt tataggaggg
     6781 actttatgat ttatacagtg actttcaatc cttcaattga ctatgtcatt tttacgaatg
     6841 attttaaaat tgatggtttg aacagagcaa cagcaacata taaattcgct ggggggaaag
     6901 gtattaatgt ctcgcgcgtc ttaaagacat tagatgttga gtcaactgcc ttgggatttg
     6961 caggtggatt tcctgggaaa ttcattatag atacattaaa taacagtgca attcaatcga
     7021 attttattga agttgatgaa gatacacgta ttaatgtgaa attaaaaaca ggacaagaaa
     7081 cagaaatcaa tgcaccgggt cctcatataa cgtcaacaca atttgaacaa ctgttacaac
     7141 aaattaaaaa tacaacaagc gaagatatag ttattgttgc tggaagtgta ccaagtagta
     7201 ttccaagcga tgcgtatgcg caaattgcac aaattacagc acagacaggt gctaaattag
     7261 tagtcgacgc tgaaaaagaa ttggctgaaa gcgttttacc atttcatcca ctatttatta
     7321 aacctaataa agatgaatta gaagtgatgt ttaatacaac agtgaactca gacacagatg
     7381 ttattaaata tggtcgtttg ttagttgata aaggtgcgca atctgttatt gtctcgcttg
     7441 gcggtgatgg tgctatttat attgataaag aaatcagtat taaagcagtt aatccacaag
     7501 ggaaagtggt taatacagtt ggctctggtg atagtacagt tgcaggcatg gtggctggaa
     7561 ttgcttcagg tttaacgatt gaaaaagcat tccaacaagc agtcgcatgc ggtactgcca
     7621 cggcatttga tgaggactta gcaacacggg acgctataga aaaaataaaa tcacaagtta
     7681 cgattagcgt acttgatggg gagtgaaaat aatgagagta acagagttat taacaaaaga
     7741 tacgatagca atggatttaa tggcaaatga caaaaatggt gttattgatg agttagtaaa
     7801 tcaattagac aaagcaggta aattaagtga tgtcgcgtca tttaaggaag cgattcacaa
     7861 tcgagaatca caaagtacaa ctggtatcgg cgaaggtatt gctattccac atgcgaaagt
     7921 agccgcagtt aagtctccag ctatcgcatt cggtaaatct aaagaaggtg tagattacca
     7981 aagtttagat atgcaaccag ctcatttatt ctttatgatt gcagcgccag aaggtggcgc
     8041 ccaaacacat ctagatgctt tagctaagtt gtctggtatt ttaatggatg aaaatgtacg
     8101 cgagaaatta ttacatgctt catcacctga agaagtacta gcgattatag atgaggctga
     8161 tgatgaagtg acaaaagaag aagaggcaga agctgaagca caacaagttg caactgcaga
     8221 acaatcatct aaacaatcta acgagccata tgtgttagca gtaactgctt gtccaacagg
     8281 tattgcacat acgtacatgg cacgtgacgc attgaaaaaa caagcggata agatgggtat
     8341 taaaattaaa gtagaaacga acggttcaag cggcattaaa aaccatttaa ctgaacaaga
     8401 tattgaaaat gcaacaggta tcattgttgc tgctgatgtt catgttgaga cggatcgctt
     8461 cgatggtaaa aatgtcgtag aagtaccagt agcagatggt attaaacgcc cagaagaatt
     8521 aattaataaa gcattagata caagtcgtaa accttttgtt gcccgtgatg gtcaaagaaa
     8581 aggtaactca aatgacagtc aagaaaaatt aagcccaggt aaagcattct ataaacactt
     8641 aatgaacggt gtttctaaca tgttgccact tgtaatatct ggtggtattt taatggcaat
     8701 tgtattttta tttggagcaa attcatttaa tccaaaaagc tcagagtaca atgcgtttgc
     8761 agagcagctt tggaacattg gtagtaaaag tgcattcgcg ttaatcattc caattttatc
     8821 tggattcatt gcacgtagta ttgcggataa acctggtttc gcttcaggtc ttgtaggtgg
     8881 tatgttagca atttcaggtg gttcaggatt tattggtggt attattgcag gtttcttagc
     8941 aggttactta acacaaggtg ttaaagccat gacacgtaag ttaccacaag cattagaggg
     9001 attaaagcca acattaattt atccactatt aacagtgaca gctacaggct tattgatgat
     9061 ttatgtcttt aatccaccag catcttggtt aaatcatttg ttattagatg gattaaacaa
     9121 tttatcaggt tctaatattg tattattagg tttagttatt ggcgctatga tggcgattga
     9181 tatgggcggt ccattcaaca aagcggcata tgtttttgca acaggtgcgt tgattgaagg
     9241 taatgcagca ccaattacag ctgcaatgat tggtggtatg attccaccgt tagcaattgc
     9301 gacagcgatg ttaattttca gacgtaaatt tacaaaagaa caacgtggtt caattatccc
     9361 taactatgtg atgggtatgt cctttattac agaaggtgcg attccatttg cagctgccga
     9421 tccattacgt gttattcctt caatgatgat tggttcaggt ataggtggcg caattgcttt
     9481 aggcttaggt tctcgaatta ctgcgccaca tggtggtatt attgtaattg ttggtactga
     9541 tggtgcacac ttacttcaaa ctcttattgc acttctagtt ggtacattag tttcagcatt
     9601 aatttatgga cttattaaac caaagttaac tgaaacagaa atcgaagctt caaaatcaat
     9661 ggacgagtag ttttaatgat gtaaaatgat tgttagcaaa gagcttcata ttaagttgta
     9721 agttcaatga atatatgtta gttttataca tcgtgttaac ggtagcttat acaaagctgt
     9781 aaaaacactt tctattaatt cagtttttat gaattgatat gaaggtgttt ttatttttag
     9841 ataaatgaat gaagaaatag acaccacaaa tgtatagact tttttaatat tttgcaaaaa
     9901 gttatgccaa acgaagcaga tatagtaaaa tatgagtgtc ttaaagtgaa aatttataaa
     9961 taaagaaggg tttatacgtg tcagaattaa ttatatataa cggcaaagtt tatactgaag
    10021 atggcaaaat cgataatggt tacattcatg tgaaagatgg acagattgtt gcaattggag
    10081 aaggggatga taaagcagca attgataatg atacgacaaa taaaattcaa gtgattgatg
    10141 ctaaaggtca tcatgtatta ccaggtttta ttgatataca tattcatggt ggttatggtc
    10201 aagatgcaat ggatgggtca tacgatggct taaaatatct atccgaaaat ttgttatctg
    10261 aagggacgac atcatacttg gccactacaa tgacgcaatc tactgataaa atagataaag
    10321 cacttacaaa tattgctaaa tatgaagcgg agcaagatgt tcacaatgca gcggaaattg
    10381 taggtataca tttagaagga ccatttatat ctgaaaataa agttggtgct caacatccgc
    10441 aatacgttgt acgcccattt atcgataaaa ttaaacattt tcaagagact gctaacagat
    10501 taataaagat tatgacgttt gcacctgaag ttgaaggtgc aaaagaagcg cttgaaacgt
    10561 ataaagatga cattattttt tcaattggtc atacagtggc aacatacgaa gaagcagtcg
    10621 aagctgttga gcgaggagct aaacatgtca cgcatttata taatgcagcg acgccattcc
    10681 aacatagaga accaggtgtt tttggagcag catggttgaa tgatgctcta cataccgaaa
    10741 tgattgttga tggcacacat tctcatccgg catcggttgc aattgcttac cgtatgaaag
    10801 gtaatgaacg tttttattta attaccgatg caatgcgtgc aaaaggtatg cctgaaggag
    10861 aatatgattt gggtggacaa aaagtaactg ttcaatcgca acaagcacgt cttgcaaatg
    10921 gtgcgcttgc tggtagtatt ttaaaaatga atcatgggtt acgtaactta atatcattta
    10981 caggtgatac attagatcat ttatggcgag taacaagttt aaatcaagcc attgcattag
    11041 gtatcgatga tagaaaaggt agtattaaag taaataagga tgcagatctt gttattctag
    11101 atgatgatat gaatgtaaaa tctacaataa aacaaggcaa ggttcacaca tttagctaat
    11161 aaataatcat aattaaatgt atgcaataga tttaatctgt taacataagc actttatatt
    11221 atgataaaat agaagcaata acattttttt ctgggggtgt ctaaatggga aggcgataac
    11281 atgtagttgt aatttaagtc atagtgataa atttgaatgc gtgttaccca tgagtgacac
    11341 atataacatg gaggtgaatc cctagaaata gggaattaat tggaaacttc gaccataatt
    11401 agtttgatta tatttattct attaattgca ttaaccactg tatttgttgg ttcagaattt
    11461 gcattagtaa aaattagagc aacaagaatt gaacagctag cagatgaagg aaataaacct
    11521 gctaaaatag taaaaaagat gattgctaat ctagattatt atctttctgc ttgtcagtta
    11581 ggtataacag taacatcttt agggttaggt tggcttggtg aaccaacgtt tgaaaagcta
    11641 ttacacccga tatttgaagc aatcaattta ccaactgcat taacgacgac gatttcgttt
    11701 gcagtgtcat ttataatcgt tacgtatttg catgtagtac ttggtgaatt agcgcctaaa
    11761 tctatagcga ttcaacatac tgaaaagctt gctttagtat atgcaagacc attgttctat
    11821 ttcggtaaca ttatgaaacc attgatttgg ctgatgaatg gttctgcacg tgttattatt
    11881 agaatgtttg gtgtaaatcc tgatgcccaa actgatgcaa tgtcagaaga agaaatcaaa
    11941 attattatta acaatagtta taatggtgga gaaatcaacc aaactgaatt ggcatatatg
    12001 caaaatatct tttcattcga tgaaagacat gcaaaagata taatggtacc tagaactcaa
    12061 atgattacac taaatgaacc ttttaatgta gacgaattac tagaaacaat aaaagaacat
    12121 caatttacgc gttatccaat tactgatgat ggtgataaag accacattaa aggatttatt
    12181 aacgtcaaag aatttttaac tgaatacgct tctggaaaaa cgattaaaat agcaaactat
    12241 atacatgagt tgccaatgat ttcagagaca acacgtatca gtgatgcatt aattagaatg
    12301 caacgtgaac atgtacatat gagtcttatt atagatgaat atggtggaac ggcaggtatt
    12361 ttaacgatgg aagatatttt agaagaaatc gttggagaaa ttcgtgatga atttgatgat
    12421 gatgaagtga atgatatcgt taaaattgat aataagacat tccaagtaaa tggcagagta
    12481 ctattggatg atttaactga agagttcggt atagaatttg atgactctga ggatattgat
    12541 acgataggtg gatggttaca atctcgtaat accaatttac aaaaagatga ttacgtggat
    12601 acaacttatg atcgctgggt tgtttcagaa atcgataacc accaaattat ttgggtgata
    12661 ttaaactatg aatttaatga agcgagacct actatcggac agtctgatga agatgaaaaa
    12721 tcagaataga tattaatata taaaccaact aagaatgatt taattcattt ttggttggtt
    12781 atttttttga ctaaaattaa tgaaaagtga aaatagtatt ggaactcaat atctttaatg
    12841 atttaatgaa tattttttat tgaaagcgat aattcgcatt aattgagttt gttgaaaaat
    12901 ttagggtaat gtaaagatat aaaagataca tagattggag agatataaag atgttgaatg
    12961 agatacaaat attaaataat ggatacccga tgccttcagt tgggttaggt gtttataaaa
    13021 tctctgacga agatatgact aaagttgtaa atgctgcaat tgacgcaggc tatagagcgt
    13081 ttgatacagc atacttttat gataatgagg cttcactagg acgagcatta aaggataatg
    13141 gcgtcgatag agaagatttg tttataacaa cgaagttatg gaatgactat caaggttatg
    13201 agaaaacatt cgaatatttc aacaaatcga ttgaaaattt acaaactgat tatcttgatt
    13261 tatttctaat acattggcct tgtgaagcag atggtctatt tttagaaaca tataaagcta
    13321 tggaagaact ttacgagcaa ggtaaggtaa aagcaatagg tgtatgtaat tttaatgttc
    13381 atcatctaga aaaattaatg gctcaatcaa gtatcaaacc aatggtgaat caaattgagg
    13441 tacatccata ttttaaccaa caagaattac aagaattttg tgatcgtcac gatattaaag
    13501 tgactgcatg gatgcctttg atgagaaata gaggactact agacaaccct gtcattgtta
    13561 aaattgctga aaaatatcat aaaacaccag cacaagttgt attacgttgg catttagcac
    13621 acaatagaat tattattcca aaatctcaga cacctaaacg cattcaagaa aatatagata
    13681 ttttagattt taatttagaa ttaacagaag tagctgaaat tgatgcttta gatagaaatg
    13741 caagacaagg taaaaatcca gatgatgtga aaattgggga tttaaaataa ctggatgtta
    13801 aattttacgt ttatgaatgc cttttaatgt gtacattaaa ataaatgagt tggtttttac
    13861 tatttgataa aacaatactc aggtacattc aaaatctttt aaataaaaag gatggacata
    13921 gatgaaaatt agagtcgtca ttccttgttt taatgaaggg gaagtcatta cacaaacaca
    13981 tcaacaatta actgaaatac tttcacaaga tagtagtgtg aaaggctatg attataatat
    14041 gcttttcata gatgatggaa gtacggatac cactatagat gaaatgcaac atcttgccac
    14101 aatagatagg catgtcagct ttatttcttt tagtagaaat tttggaaaag aagcagctat
    14161 gattgcaggt taccagcata gtactgaatt tgatgcagtc atcatgatag attgtgattt
    14221 gcaacatcca cctgaatata ttccgaaaat ggttgaaggt tttatggaag gctatgatca
    14281 agtgattgca aagcgtgata gaagtggtga aaattttagt cgcaaaacat taagccattt
    14341 gtattataag ttagttaatt gctttgtaga agaagtacaa tttgatgatg gtgttggtga
    14401 ttttagactt ttaagccaaa gagctgttaa atccattgca tcacttgaag aatataatcg
    14461 attttcaaaa gggttatttg aatggatagg ctataatact aaagtgttta cgtatcaaaa
    14521 tgttgagaga caaaaagggg aatctaagtg gtcctttaaa aagttattta attatggtat
    14581 tgatggattg atttccttta atagtaaacc tttgagaatg atgatttatc ttggcttgtt
    14641 tatcttttca ataagcgtgc tatatattat ctatttattc atcaatatta tgatatctgg
    14701 tgttaatatt ccaggatatt tttcaacgat tgcagctatt ttattattag gcggcataca
    14761 gttaatttca attggtgttg taggtgaata tattggcagg atatattatg aagttaaggc
    14821 acgtcctaaa tatattattc aagctacaaa tctttcaagt attgaaaatg atgagaagga
    14881 tacccataaa gtttattcta aataaacaaa aaaagaagcc ctcattaatg ggagcttctt
    14941 tttagtcttt gcattttatt ttataaataa atcggattat gacgtaatgt ctaatttgtg
    15001 taatgttaca gtcatcgtag ttcctacatc tatatcactg cttacactga tttttgcgtt
    15061 attttgttgc gcgagttcat tagctatata taagcctaat ccagaaccac ccgtttttgt
    15121 attacgagag ttttctactc tgaatgtacg ttcgaatata cgttcttgta gttctggtat
    15181 aatgccaata ccttcatcgc taatagcaat gtcgatagta tcttgatctt tgttttcact
    15241 aatattaata tcaatgcgac taccaacatt tgaaaatttt agcgcattat caagtaagtt
    15301 tgttaaaata cgctcaagtg gcgttcgata ttgataaaat gcatcaattt cgctacagaa
    15361 attcacttct aatgtgcggt tttcatgttt gatacgttgc tcatatggtt gcaatattga
    15421 tacaagtaat tggtctagtt gtattaattc tgggggatat gttttacctg tatttaaagt
    15481 gataatatga gtcatatcat caaataatgt tgataatctg tttgcttgtt taattaatat
    15541 gtcgtatgac tctttaatct catgatcctt tgtgattata ccatcacgta gtccttcaga
    15601 atatgaaata atgcttgcta aaggtgtttt taaatcatgg gctaagtttt gaatcagttc
    15661 tgttttttct tgttgttcgg atttaatttg attcatttgt tgcgtaattt cagaagccat
    15721 tttattaaaa gattgattta attcataaat ttcttttggt gaattaaacg ttttatcatt
    15781 gcttgcgtaa tttccgttag caaattgctt agtttttata ttaaactgct taattttttg
    15841 tataagtgga ttaataaaaa tactacatat taataaggtt aaacagcttg taattattgt
    15901 cgttaaggtc aaagttagtg tcatatggcc gttaaaccac attaaaatat atgcaattgc
    15961 taaaatagtt gaagttaata gtatactcga tacgacgcca ataatgattt gacttctaat
    16021 tgataacacc attatcggct cctttcaaat ttatatccta atccccatac agttgtgatg
    16081 gtatatgttg taaagctctc tttttctaat ttttctctaa tacggtgtat atggacattc
    16141 acggtattag catcttcgta atagtcatat ccccaaactt tttcaagtaa ttctgattta
    16201 gaaataactt cattttctct agaagctaaa taccacaata actcaaattc cttaatacgc
    16261 atagggactt cgtgaccatt tacagtcaca actttactta agttaataag tgttaattca
    16321 tcaaacgaca gttgttcaac tggttgatga tggtatttct tcattcttgt aagtaaatta
    16381 ttaatacgta aaacgagttc ccttggacta aatggttttt tgacatagtc atctgcacct
    16441 aaagttaagg cgtaaatggt atcatgttct tgtgttttgg cagttaaata gataaagggg
    16501 atatctaatt tttgcctttt catttctttg acaatgtcgt aaccattaac ttctggcatc
    16561 atgatatcaa gtaccatgat atcaatatca tttgatagta aagaaattgc ttctttaccg
    16621 ctagttgtcg ttgttacttt gtaaccttca tattcaaaat aggtttgaca aatgtctaca
    16681 atgtcttgtt catcatccac gatcagtaag tgggtcatct attttttcac ctctgttctt
    16741 acgacctcta aagtaattaa tgatttcttt aagtgaaatc tgttttaaca atgagtgact
    16801 cattagtaaa aggataaaga aagttaattg aagaggatac gtaaatatca tatctgctaa
    16861 gatataattt atcataacaa aggctccaaa gaaactagca gcatatgcaa aaactccaaa
    16921 aattaaacct aatccaattg caatctctcc gagtgggaca acaatatcaa ataatgacgt
    16981 cgtatgtgca actatatttg cgaaaaacca cttataccac tctggtgaat cagtattgtt
    17041 agcgatgact ggtactaaac ctttcagcgt aaatccgccc gttaattttt cgtagccttg
    17101 cattaacata acaatacctg aacccacacg aatgataaat gtaacgagta gcaataattt
    17161 attcatgatg ttcacattct ttctatttat tgtgtgtaat ttatataaac ataagattaa
    17221 gcaacataat gcgatttgta gtgttatgtg aacaggaagt gtttgagctc atgggttgct
    17281 taagctaaac aaacctcaag ctctaaaaaa attttactta tgtgctctac aatcttatgg
    17341 gatttaatag ttgtatatat attgaaaaaa ggaaagtatg atttctacaa gctagggggg
    17401 ctgtgaaatc atacgctttc cattgagtaa tgagtgtaat gtatattttt aaaatttgta
    17461 atgtatagta atagtatgtt gtatataaaa gtttaactca gaaattgatt attttaattt
    17521 agcgccgccg aagatgacgt gagctttttt acaatagatt gttacttcat catatttgct
    17581 taaatctaca tttttaagat caaatgtttg tttttcttta tcgtagtcaa ccattgcgat
    17641 ttctttaccg tttttaatgt cgccattttt tgttaggtag acgtataaat ctggaccttt
    17701 tgatgatttg tagttagtaa gcattaattt accattttta atctcagctt taccttcaac
    17761 agtttcaccg tttttagaac tgaatgtacc tgttaggtgt tttgttttat cagttttaac
    17821 attgctatct tctgactttg ttttttgttc agttttgtta ccttgatctt gtgaattaga
    17881 attaccacaa gcgcctaaag ttaatacaga ggcaacagca ccaactgcta aaaaatattt
    17941 tgtattcatg ctaactcctc atttcttcaa tttgataagt taagtttaaa atgaaggcaa
    18001 ataatatgcc attaactaat tcttaacttc gtttaaatat cgcttaacta atattgaaga
    18061 aagaataatt tgaaaatgaa aataattgtc tgatttaaat aaataggagt caaaataaga
    18121 ggagggcatt tttttaggtg agaaaatatt tatctgaact agataacact ataaaacact
    18181 tctgatattt tgaactaaga atatcagaag tgttttatag ttttggtatt aaaatttata
    18241 aaccttttgc cacaataaaa acaacaagaa aataagatag acgattaaat acaagtacca
    18301 atatggtgtt aaaaccatca taacgataaa tgaaatgtta ataatgataa gtcctttaat
    18361 cattagtttc tttattttgt tattattttc agcagtttca tctaagctat taaatgttga
    18421 aataaacaac ataataccac caatgatgaa aattgcaggg gctaaaaatg gaatagacat
    18481 atatattgat tgtgtacttg aaaagtcggt aacacgttgc gttaaactga caacaatcgt
    18541 taatatgata gcaataaatt tttggtctgt aatgtataca ggttttaatt ttttatcaat
    18601 gtaaaactgt agtatcgtcc aaatgataaa catcgttata gtacacagag taataaagtt
    18661 atatttatca attatgaatg tatttataaa ggcgtttatc gtaatagata acaacattgc
    18721 acttaatgat aaatgttgca tttgatgcct atataaattg aatccagtta taagtacgac
    18781 gatagcaata ttaattaata tatataaaat catgatggac tcctgttcgt tatacttcaa
    18841 tcaactatta tatcaattaa tatattgtta ttcattagat atgacttgta aaaagtaaaa
    18901 taagttatcc tttatacacc ttttttatta ctccaaagta atgtatgaag ttgtggtaac
    18961 acataaacgt gattcatatc attactttgc ataactaaat ccaccaactg ctcgtagcgt
    19021 tctaacaact tttcggtatg attatctacg ctgtctgata aatatgggtt accaacttgt
    19081 aaatagaagg gaatatctgg ataacggtgg tgtatcattt tggcaaaatc ataatcttta
    19141 tcgtcgaata caactacttt taagtttaat gaggaaggta cgcattgtgt aatcacttca
    19201 tctaactttt ttaaatcagg tgtcatagtt gaacttggtg gttttggact aatcgttaaa
    19261 tcatcaattt gtgtcatcca aggttggaat ttactgcctt gtgtctccag tgcgctgaaa
    19321 atacctttat cttgaaataa gtcaactaac tcttggatac ctttaattaa tgctgggtta
    19381 ccaccagaaa ttgtaacgtg attaaataaa tcgccaccaa ttcgttttaa ttcatcataa
    19441 atttcttcag cggtcatgag ttttatatcg cctttagcac taccatccca agtaaatgca
    19501 gaatcacacc agctacagcg ataatcacat ccagctgttc tcacaaacat cgtttttcta
    19561 ccgattactc gaccttcacc ctgaatggtt ggaccgaata tttcgagtac aggaatttta
    19621 gccattagtt acacctgttc ctttggtcta aatacaacat aacttgttgg tgtttctctt
    19681 acaaatactt gaatacattt tggttggtgt tcgagcgatg ccaaattttc tttaacaatt
    19741 tgataaattg tttccgctac gatttcagtt gaagggattt tgtttttaaa agcaggtaag
    19801 ttatttaaca gttgatggtc aaatttaccg tgtatcatct ttttcaaatg gctaaagttc
    19861 actaagaagc cagtgtcatc tagtttatca ccgacaattg ttaaattaac aaagtaagta
    19921 tgaccatgga cattttgaca aatacctgct tcttcacaag gaatgtgatg tgcagccgaa
    19981 aaattaaaat ctttatttaa ttcgaattga tatggatgcg ttgtactagg atagatttgt
    20041 tgtaacattt taaagcgctc ctttactttc aagatattga tttagtccac gttgacgtaa
    20101 atgacaagct ggacattcac cacagccatc cccaatgata ccgttatagc atgttaatgt
    20161 ttttgtacga atataatcta aaacttcgag ttcatcactt aatttccacg tttctgcttt
    20221 gtttaaccac attaaaggag tatgaatgac aaaatctttg tccatagcta ggcttaatgt
    20281 tacgttcatt gattttataa aactatcgcg acagtctggg tagcctgaaa agtctgtttc
    20341 acatacgcct gtaataatat gcttagcccc aatttgataa gctagagcgc ctgcaaacga
    20401 caagaaaagt aaatttctag ctggaacaaa tgtattaggt ataccatctt cattattagt
    20461 aatttccata tcatgttgtg ttaatgcgtt tggagtaagt tgtgataata atgacatatc
    20521 taaaacgtga tgtttcattc cttgatcttg tgcaatttgt tttgcgactt caatttcagt
    20581 atcatgtctt tggccataat taaacgttac gagttcaact tctttgaaat gtttttttgc
    20641 ataaaagaga catgttgtac tgtcttgacc accactaaag acaacgatgg ctttttcatt
    20701 atttaataca ctttccattt tgtaattgct cctatcatta ataatattaa taaagaggtt
    20761 aatggcattg ataagcccgt ttttaattta taaaataaaa aaagcctatc tccataaaag
    20821 atagacgaaa gaaatgggtt gctcctataa tatatattaa aggtttacca acgaatgttt
    20881 gaaatttcaa tgtctagttt tttatagagg gtttcagcta gaaacctctg atattcattt
    20941 atgtacgatg aatagaatat accatatatt agttaaaatc aaggtcagga taatgacaat
    21001 gcttttaaag ttttagctac atccaataca tattataaaa ataaaacaca tttagaacgg
    21061 agtatacaat gattctagtc atagataata atgattcatt tacatataat ttaatagact
    21121 atattaagac tcaaacgaaa ctaacagttc aagttgttgg tattgataat ctgctgatag
    21181 aagacgtcat taatatgaag ccaaaagcaa ttgttatttc gcctgggccg ggtaatccgg
    21241 atgattatcc tatcttgaat gaagtgttag aacaatttta tcagcgtgta cctatactag
    21301 gtgtatgttt aggatttcaa tgtatcgtgt cttattttgg tggaaatatc attcacggct
    21361 atcatcctgt acacggacat actacacagt tacgccatac caatgaaggt atttttcaag
    21421 gactgcctca aaatttcaat gtaatgcgtt atcattcatt aattgctgac ggagcgactt
    21481 ttccaaattg cttaaagatt acagcaaaaa acgatgaagc gattattatg gcatttgagc
    21541 atattagatt tccggttttt ggtgtgcaat atcatcctga atctattttg agtgaatacg
    21601 gttatcgaca agttgaatta tttttatcga aggtaggtga ttactgtgag aatagaatat
    21661 aattatcgct actatttaac tgaaaatgaa tataagcaat accatattca attaaaggga
    21721 tttataaaga agtatgttgc tactaagttg gctgatgtgg gagaagtgat acactttgca
    21781 caagcgcagc aacgacaagg tagatatgtc tcgttatatt taagttacga agcggcaaag
    21841 tattttaatc atgttatgtg tacacattca ttagctaaag atgatattta tgcagtagct
    21901 tatagttttg aaaaagcgga aagcataaat tcaacatatg aacatcaaac ttcttatgta
    21961 tcaaagcatc atttttcatt tgttgaatct tctgaggtta tgatgactaa tattaaacgt
    22021 gtccaacaag caattgttga aggtgaaacg tatcaagtga actatacggc gcgcttaacg
    22081 gataacattt attatcctat tagtacttta tatgaacgat taactcaatt tagtaatggt
    22141 aattatactg cgttattaca aactgatgaa atccaagtag cgtctatctc accagaatta
    22201 ttttttcaaa aaggacaatt taacaatgtc gataacgtta tcataagcaa accgatgaaa
    22261 gggacaatgc ctagaggtaa aacggaagct gaagatcaac agtattataa aacattgcaa
    22321 acttcttcga aagatcgtgc agaaaatgtc atgattgttg atttgctaag aaacgatata
    22381 gggagaatat cacagagtgg ctcaattaag gtgtataaac tattttttat tgaggcatat
    22441 aaaactgtat ttcaaatgac ttcgatggta agtggaactt taaaaactaa tacagactta
    22501 actcaaattt taacatcgtt atttccttgt ggttcgatta caggtgcacc gaaactgaat
    22561 acaatgaaat atattaaaca atttgaaagt tcacctcgtg gtatatactg cggagcaatt
    22621 ggactattac ttccaactga agatgataaa atgattttta atattccgat tcgtactatt
    22681 gagtataaat atggacaagc gatttatgga gtcggagcag gtattacaat tgattctaag
    22741 ccaaaagatg aagtaaatga attttacgca aaaaccaaga ttttggagat gttataatgc
    22801 aattatttga aacaatgaaa attgataatg gatatatccc tagacttact tatcatacta
    22861 atcgcataaa atgttcttct gagcgattaa actttaaatt tgatgaacat gcatggcgaa
    22921 atgaattaaa cgatgtaaca acaaagtatc acagtggtca atatagactt aaaatcgtat
    22981 taaatgctga aagcaaattt gaaacgatag tgtcaccttt acctgagaaa agtagtttta
    23041 cagcaaaatt tcaagtgttg cccaaagtag ttaatccaac ttttataaaa aataaaacga
    23101 cagaacgaaa gcatttagca cacaatcatg aaacagattt aatattgcta acttcagagg
    23161 acggcaaggt ccttgaattt gatattggca acattgtcat tgaagaggat ggaaaatggt
    23221 acacaccaag ttataaagat gatttcttaa aaggatgcat gcgtgattat ttaatagata
    23281 gtgacaaact tgttgaaaaa gactttaata aaaacgaatt gatttataaa tatcataaca
    23341 atgagatacg tttatttttg ataaatagtt tacgagaggt tgccgatgtc cacctttgcc
    23401 tttaaaatta gtatgataat aaagtagaaa atgatgtgaa aacaaattta aaaattaaat
    23461 ggggccaaat atgattattg tttatattgt gctgttgtta attcttgtat acgtaaatta
    23521 tcgattagtg aatcgattgc tatctgaaaa tagaatatat gttgttcgtt tgatagtaac
    23581 aattactact gttataagct ttatccttgt atacgcatta attcacgaac ttatgccttt
    23641 tgttgtgcgg gcaatggatt taatgtacca ccagtaaatt tagtgagtag gtaaaacgaa
    23701 ctattcaatc gattctataa ttaaaaatga aagtaaagta accaaatatt gaagaggtgt
    23761 acaaatgaaa atatatagtc aaggtgacca agccattgta gtcgcaattg aaaaagaagt
    23821 atctaaaagt ttaaccgaag atttattaac acttcgctca tatttaattg aacaaaatta
    23881 tccatttatt atagaaattg tgccatcaga atcagacatg atgattgtct atgacgcaag
    23941 ggatatgatt aaacaccata atatacaatc acctttttta tacatgaaag cactaataga
    24001 atcgattcat ttaaacataa aacatgattt taaccagcaa gatttgattg aaataccaat
    24061 tgtgtatggt tcgaaatatg gtccggatat agaatcactt ttaaaacatt acaaaatcaa
    24121 gctagaaact tttattgaat tacattctaa gacgcaatat tttgtttcga tgatgggata
    24181 ttcacctggg tttccttatt taactggatt aaataagaaa ttgtatatta atcacacgag
    24241 taaacagaaa aaattcattc cagctggttc tgtagtactt gaagggaaaa aatgcggtat
    24301 tgtaacaacg gatacaatta atgattggtt agttattggt tatacaccat tatcactttt
    24361 taatccgaaa gaatcagatt tcgcacgctt aaagttaggc gataatatta aatttagacc
    24421 tatcaatgaa aatgaattag aagtaggagc gtttaaagat gtcaatcata attgaaaaaa
    24481 gtggcttatt cagtagcttt caggactttg gtagaagggg atatgaacat gatggtgtaa
    24541 ttccatgtgg tgcacttgat actttagcac atgaaattgc taatcgatta gttgctaatg
    24601 acaagaatga agcaactttg gaaatgacta ataaaatggc aacgattcgt tttacagaac
    24661 ctacgctgat tgcattagca gggggtaatg tcaaagctta cactgagcat atgactatat
    24721 ctccatataa attgtatttg ttagataaag gcgatgtttt aaagtttaga gaaacaagtt
    24781 atacatcgcg agtgtattta gctgtgggag gcggatttga attagatgca tggttaggat
    24841 ctaactcaac cgactttaat gtaaaaattg gtggttttaa aggtagaaca ttacaagatg
    24901 gcgatgaaat aaagcttaag agagattata cagctcgtca tcataagtta tttgaaaacc
    24961 ttgctcacac gaaacaaaca gattggggta ttgatggata cgccttgtca tttaattata
    25021 tgtctgatgt atttcatgtc gttaaaaata aaggtacgga agattttaaa gaagatgcca
    25081 ttcaaagatt tgtgaaacat gattataaag taacgagcaa agcaaatcgc atgggaatga
    25141 tgcttgaagg tgaaaaaatc aaagcttttt atgaagatat gccgccgtat cagactgtca
    25201 aaaaaggaac gatacaaatt aagcgtgatg gcacacctat tatcttatta aatgatcatt
    25261 atacgttagg tagctacccg caaatcggta caatcgcaag ttatcattta acgaaattag
    25321 cacaaaaacc gcaaggatca cgtttgaaat ttcaatttat agatatttta acggctgaaa
    25381 agaaccttgt taagtatagt aactggttaa accaattatt ccatggaata gaatatagaa
    25441 tgcaattaga aatgatgaaa taatatttgg tacgtagctc atactcgagt ccgatgcaaa
    25501 taatttcctc ctaatgtata atgaaataat actgtgtttt atctgcgaaa tgtatcattt
    25561 tctaattcgt ttcacagtaa aatgaaaaga taaagtgtgt ttttacttga attttgacta
    25621 aaattactct atatttatta attgagctat gcttattatt acaatttgat tacaaatttt
    25681 aaatttgtta attgaatgat aatattaaat aaagaaactt acacaagcaa atatgagttg
    25741 tagcccaaaa tacttgttaa atcaaagttg aaagctacaa gtaatgaaaa ttataaactt
    25801 gaatctgaaa gtaattacta taattatgac aatgttaact tttaaacgca cttattaatt
    25861 aactacataa tgttaatatc taatttattc aagtactttc gcaagattta ttatctaaat
    25921 aacgggggaa agaatcatga gttcacaaaa aaagaaaatt agtctttttg cgttcttctt
    25981 attaaccgta ataacgatta ccttgaagac gtatttttct tattatgttg atttttcttt
    26041 aggtgttaaa ggtttagtac aaaacttaat attattgatg aatccttata gtttagtagc
    26101 actggtttta agtgtgttcc tattctttaa aggcaaaaaa gcattttggt tcatgttcat
    26161 aggcggcttc ttattgacgt tcctattata tgccaatgtt gtgtacttta gattcttctc
    26221 tgatttttta acgtttagta ctttaaacca agtaggtaac gtagaatcta tgggtggtgc
    26281 ggttagtgca tcattcaaat ggtatgactt tgtttatttc attgatacgt tagtttactt
    26341 attcatttta atatttaaaa caaaatggtt agacacaaaa gcatttagta agaaatttgt
    26401 tcctgtcgta atggcagctt cagtagcatt attcttctta aacttagctt ttgctgaaac
    26461 tgacagacca gaattattaa cacgtacatt tgaccataaa tatttagtga aatatttagg
    26521 accttataac tttacagtat acgatggtgt taaaactatc gaaaataatc aacaaaaagc
    26581 gttagcatct gaagatgact taacaaaagt attaaattat acgaaacaac gtcaaacaga
    26641 gcctaaccca gaatattatg gggtggcaaa gaagaaaaat attattaaga ttcatttaga
    26701 aagtttccaa accttcttaa ttaataaaaa ggttaatggt aaagaagtaa caccgttttt
    26761 aaacaaatta tcaagtggga aagagcaatt cacatacttc cctaactttt tccatcaaac
    26821 aggtcaaggt aaaacatctg actctgaatt tacaatggat aacagtttat acggtttacc
    26881 gcaaggttct gccttttcat taaaaggaga taatacgtat cagtcattac cagcaatttt
    26941 agatcaaaag caaggctaca aatctgatgt catgcacggt gactataaaa cattctggaa
    27001 cagagaccaa gtatataaac actttggtat cgataaattc tatgatgcaa catactatga
    27061 catgtcagat aaaaacgttg taaacttagg cttgaaagac aaaattttct ttaaagattc
    27121 tgctaattat caagctaaga tgaaatcacc attctattct catttaatta cattgactaa
    27181 ccactatcca ttcacattag atgaaaagga tgcgactatt gagaagtcaa acacaggtga
    27241 tgcaacagtt gatggttata ttcaaacagc gcgttattta gacgaagcat tagaagaata
    27301 tattaatgac ttgaagaaaa aaggattata tgacaattca gtgattatga tttatggtga
    27361 ccactatggt atctctgaaa accataacaa tgccatggaa aaactattag gtgaaaaaat
    27421 cacaccagct aaatttacag atttaaacag aactggtttc tggattaaaa tccctggtaa
    27481 atctggtggt atcaataatg aatatgctgg tcaagtcgat gtaatgccaa caattttaca
    27541 tttggctggt atagatacga agaattattt aatgttcggt actgatttat tctctaaagg
    27601 tcataatcaa gtagttccat tcagaaatgg tgactttata acaaaagatt ataaatatgt
    27661 taatggtaag atttattcta ataaaaataa tgaactcata actactcaac cagctgattt
    27721 cgaaaagaat aaaaagcaag ttgaaaagga tctcgaaatg agtgacaacg tgcttaatgg
    27781 tgatttgttt agattctaca aaaatccaga cttcaaaaag gtaaatcctt cgaagtataa
    27841 atatgaaaca ggacctaaag caaactctaa aaaataatat ttaaacacga actcggattg
    27901 ataaaatatc aatccgggtt ttattatgtt cttttatatt atgttttaca gtatatgtgt
    27961 tgataaaaag gtatattata aaaatcatta gcatagtcat caaagcctta tcaagtttta
    28021 tttatagttg aagcaacaat atattaaatt atgacactta acggtatcga tttcttttga
    28081 tttcaaaaag gtgtataatg tatagaactg atttaagtac gtagagattt caacagaaga
    28141 aggaagatgg gtatggaagc atataaaatt gaacatttaa ataaatctta tgccgataag
    28201 actatattcg ataacctaga tttatcaatt tcagaaggtg aaaaaatagg tttggtgggc
    28261 ataaatggta cagggaaaag tacgttgtta aaagtaattg gtggtattga tgatgatttt
    28321 acagccaatg ttatgcatcc aaatcaatat cgaattcgat attcgtctca gaaacaggac
    28381 cttaatgaag atatgacagt ttttgatgca gtattaagtt ctgatacaac aactttacgc
    28441 atcatcaagc aatatgagca ggcagtacaa gcttatgcgg atgaccaaag tgataaattg
    28501 ttcaagcgaa tgatagatgc gcaagatgct atggatcaac atgatgcttg ggactataac
    28561 gctgaaatta aaacaatcct ctcaaaacta ggtatacatg atactactaa atacattaaa
    28621 gaattatccg gcggacaaca aaaacgtgtt gtacttgcta aaacattaat agaacaacca
    28681 gatttattgt tattagatga acctacgaac catttagact tcgaatcaat cagctggttg
    28741 atcaattatg tgaagcaata tcctcataca gttttattcg taacccatga tcgatatttt
    28801 ttaaatgaag tttccactag aattattgaa ctaaacagag gtaagttagc gtcatatcct
    28861 ggtaactatg aatcttatat tgaaatgcgc gctgaaagag aagtaacact tcaaaagcaa
    28921 caacaaaagc aacgagcttt atataaggaa gaacttgctt ggatgagggc tggagctaag
    28981 gctcgtacta caaagcaaca agctagaatt aatcgattta atgacctaga aaatgaagtt
    29041 aaccagcaat ataaagacga taaaggtgaa ttgaatcttg cttattcaag attaggtaag
    29101 caagtgttcg aattagaaga cttatcaaag gctattaatg ataaagtatt atttgaacat
    29161 ctgacggaaa ttattcaaaa aggtgagcgt attggtgttg ttgggccaaa tggagctggt
    29221 aaaacaacac tcttaaatat tttgagtgga gaagaccaac aattcgaagg taaattgaag
    29281 actgggcaga cggttaaagt agcttatttt aagcaaacag atgagaccct ggatagagat
    29341 attcgtatga ttgattattt aagagaagaa agtgaggtcg caaaagaaaa agatggaacc
    29401 tcggtatcta ttacacaact tcttgaacga tttttatttc caagtgcaac tcatggtaaa
    29461 aaagtttata aattatctgg tggagagcaa aagcgtttgt atttattacg tctactcgta
    29521 caccagccaa atgttctgtt gttagatgaa ccgacaaatg atttagatac tgagacttta
    29581 acaatacttg aagattatat tcatactttc ggtggtacag tgattaccgt aagccatgat
    29641 cgctacttct taaataaagt tgcacagtca tattggttta ttcatgatgg tcagatggaa
    29701 aagattatcg gaacttttga agattatgaa agttataaaa aatcattaga taaaaataaa
    29761 tccacattga agcaacaatc taaatcttat acaactgtac gtaagaaaaa tggtttatca
    29821 tataaagaaa aattagaata tgaacaattg atgaaacgca tagaacaagc ggaagtaaga
    29881 atggaagaaa ttgatgtgct catgattgag gcaagtgcag attatgggaa aattaaagaa
    29941 ctaaacgaag aaaaagaaca acttgaaatt caatatgatt tagacatcac aagatggagt
    30001 gagttagaag aaattaaaga acaacaataa ggggtcaatt tatgatgcaa caaacattat
    30061 cgcattactt tgggtatgaa acatttcgac caggacaaga agaaattatt agcaaagtat
    30121 tagaccatcg taatgtgctt ggtgtcttac caactggtgg aggtaagtct atatgctatc
    30181 aagtaccagg tttattgtta ggtggtacaa caattgtaat aagtccacta atatcattaa
    30241 tgaaagatca agtggatcaa ttaaaagcga tgggaattca agctgctttt ttaaatagta
    30301 gtttgactca aaaagagcaa caacgtattg aaaaagcatt atcaaatgga gaaattcaat
    30361 ttttgtatgt tgcaccagaa cgatttgaaa accgatattt tttaaatatg cttcagcgta
    30421 taaagattca cttagtcgcg tttgatgaag cgcattgtat ttctaaatgg ggtcatgatt
    30481 tcaggccgag ttaccaaaat gttatttcaa aagtatttac gttacctcaa gattttacaa
    30541 taatagcgtt gacagcaact gccacggttg aagtacagca agatattaga gaaaagttaa
    30601 atatcgctca aactgatcaa attaaaacga gtactaagcg tagaaactta atttttaaag
    30661 taaatcctac ttatcaacgt caaaaattta tattggatta tattaaaaca catgatgaag
    30721 atgcaggtat tatttattgt tctacacgta agcaagttga agagcttcaa gaagccttag
    30781 aaagtcagaa aattgaaagt gttatatatc atgcaggttt gagcaataaa gaaagagaag
    30841 aagcgcagaa tgatttctta tttgatcgtg ttaaagtagt cgttgctaca aatgcttttg
    30901 gtatgggtat tgataaatcc aatgtacgtt ttgttattca ttataatatg cctggagatt
    30961 tagaatctta ttatcaagaa gcgggtcgtg caggtcgtga cgggttgaaa agtgaatgta
    31021 ttttgttatt tagcgaacgc gatatcaatt tacacgagta ttttataaca gtctctcaag
    31081 ctgatgatga ctataaagat aaaatgggcg aaaagttaac taaaatgatt caatatacaa
    31141 aaacaaaaaa atgtctagaa gcaacaattg tccattattt tgaaccgaat gaaaaattag
    31201 aagaatgtga acaatgtagt aattgtgttc aacaagataa atcatataat atgacacaag
    31261 aagctaagat gattattagt tgcatcgctc gtatgaaaca acaagagagt tatagtgtta
    31321 tcattcaagt gttaagagga gagtcaacag attatattaa gtataaaggt tatgaccaaa
    31381 tttcaaccca tggtttaatg aaaggttaca caacatcaga attaagtcac ttaatagatg
    31441 aattaagatt caaagggttc ttaaatgaaa atgacgaaat attaatgtgt gatacttcaa
    31501 ttaaaaaatt actcagtaat gaagtagaag tattcacaac accatttaag caaaaagcga
    31561 ctgaaaaagt atttataaat acggttgaag gggttgaccg agtattattc agtcagttgg
    31621 tagaagttcg taaaaagtta agtgacaaat taacgatagc acctgtaagt atattttctg
    31681 attacacgtt ggaggaattt gctaaacgta agcctgcttc gaaacaagat atgattaata
    31741 ttgatggcgt aggtagttac aaattaaaac attattgtcc agcattttta gaaacgattc
    31801 aaaattataa agccaaagta tagtgaaggc acctagtaag cattccttgt tttactgggt
    31861 gtttttttga attcaaggta aaataacact atttcttaac tggagattac ctattattca
    31921 ttattttgtt aaaaaagttc aaggataaat catttaaatt tgaaaattgt aataaacgtg
    31981 gttaaatagg gaatacatac atataatctc ggttttatgc tatgagaaaa aaagaggtgg
    32041 caaagtgatt aagtttaaaa atgtaactaa gcgttatggc aaacatgttg ctgtcgataa
    32101 cattagtttc aatattaatg agggtgaatt ttttgtgcta attggacctt caggttgtgg
    32161 aaaaactacg acattaaaaa tgattaatcg actcattcac ttaagtgaag gttatattta
    32221 ttttaaagat aaaccaataa gtgattatcc agtatacgaa atgcgttggg atattggata
    32281 cgtattgcag cagattgcat tattcccaca tatgacgatc aaagaaaata ttgcacaagt
    32341 gccacaaatg aaaaagtgga aagaaaaaga tatagataaa agagtagatg aattacttga
    32401 tatggttgga ttagaacctg aaaaatataa aaacagaaaa cctgatgaat tgtcaggggg
    32461 gcaacgacaa cgtgtaggag ttatacgtgc gttagcagct gatccaccag ttattttaat
    32521 ggatgaaccg tttagtgcat tagacccaat cagccgagaa aaacttcaag atgatttaat
    32581 tgaattacaa actaaaatta agaagacaat catatttgtt acacatgata ttcaagaggc
    32641 gatgaaactt ggtgataaga tttgtctttt gaatgaaggg catattgaac aaattgacac
    32701 accagaagga tttaaaaata atcctcaaag tgaatttgtt aaacaattta tgggtagtca
    32761 tttagaagat gatgcgccat gtgttgaaga gaacgcaatt attcgtgact tggatattat
    32821 gaaaccaatc gatgaggtta catctatgag cgcttatcca attgtttatg acaatcaacc
    32881 aattgaagta ttgtatcaac atttatcaga gagcgagcgt gtcattgtca tgcaagaaga
    32941 tagcgtaggt caatatgtta ttgataggaa agatatcttc aaatatttgt cccagaaaaa
    33001 ggaggtagct caacatgact aactttttcg acatattgag tgaacgtaag gggcaactct
    33061 tttcgacaat gatagaacat attcaaatat catttattgc attattgatt gcaactgcta
    33121 ttgcggtacc attaggtatt ttattaacga agactaaaac gatatctgaa atcgtaatga
    33181 atattgcggc aattcttcaa accataccat cgttggcatt attaggttta atgattcctt
    33241 tatttggtat cggtcgtgtg ccagcaatta ttgcacttgt agtgtatgcg ttgttaccaa
    33301 ttttaaggaa tacgtatact ggaattaaag aagttgatcc atcactcatt gaagcggcta
    33361 aaggtatagg tatgaaacca tttagacgtt taactaaagt cgaacttccg atagcaatgc
    33421 ctgttataat ggctggtgta agaacggcta tggtattaat tataggtaca gcgacactag
    33481 cagcattaat tggtgcaggc ggactaggag atttaatttt attaggtata gaccgtaaca
    33541 atgcgtcatt gatattatta ggtgcaattc cagcagcctt attggcaatt atatttgatt
    33601 taattttaag atttatggct aaattatctt ataaaaagtt attgatgacg ttaggtgtta
    33661 tagtgatgat tattatactg gccatcgcta ttcctatgtt tgcacaaaaa ggtgataaaa
    33721 ttacgttagc tggaaagctt ggctccgagc cttcgattat tacaaatatg tataaaattt
    33781 taatagaaga agagaccaaa aatactgtag aagtgaaaga tggtatgggg aaaacagcat
    33841 ttttatttaa tgctttaaaa tctgatgata tagatgggta tttagagttt actggaacag
    33901 ttttaggtga attaacaaaa gaaccattga agtcaaaaga agagaaaaaa gtttatgaac
    33961 aagctaagca aagtcttgaa aagaaatatc aaatgactat gttaaaacca atgaagtata
    34021 acaatacgta tgctttagct gtaaaacgtg attttgctaa acaacataat atacgtacaa
    34081 ttggtgattt aaataaggtt aaagatcaac ttaaaccagg atttacattg gaatttaatg
    34141 atcgtccaga tggttacaaa gctgttcaaa aggcttataa tttaaattta gataacatac
    34201 gtacaatgga acctaagttg agatatcaag cgatcaataa aggtaatatt aatttaatag
    34261 atgcatattc aactgacgct gaattaaaac aatatgatat ggttgtgtta aaagatgata
    34321 agcacgtatt tccaccatat caaggagcac cattatttaa agaaagcttt ttaaagaaac
    34381 atccagaaat taagaaaccg ttaaacaaac tagaaaacaa aatatctgat gaagatatgc
    34441 aaatgatgaa ctataaagta acagttaaaa atgaagaccc atatacagtt gcgaaagatt
    34501 atttaaaagc aaaagggtta atcaaataac gaccaacgcc acataagatg cgtaacacca
    34561 aattatatct tatgtggcgt tgttatattt aaatctataa ttatgttcaa tttaaacatg
    34621 caataatgat taaaaaatat gacatgttaa acacaatgta agctattatg atgtgaaaat
    34681 agtagcattg cattttagaa acatagagcg atataatgaa tataagtttt ttaaaatttc
    34741 agttaattct aaggaggttg tttttattat gaaagaacaa cttaatcaac tatcagcata
    34801 tcagcctggt ttatctccaa gggcattgaa agaaaagtat ggcattgaag gagatttata
    34861 taaacttgca tcaaatgaaa atttgtatgg accatcgcct aaagttaaag aagcgatatc
    34921 agcacattta gatgagttat attattatcc tgaaacagga tcaccgacat taaaagcggc
    34981 gattagtaaa catttaaatg tagatcaatc acgcatttta tttggtgcgg gattagatga
    35041 agttatatta atgatttcta gagcagtatt aacgccaggg gatactattg ttacaagtga
    35101 agcgacattc ggtcaatatt atcacaatgc gattgttgaa tcagctaatg tgatacaagt
    35161 acctttaaaa gatggtggct tcgatttaga aggtatttta aaagaagtta atgaagatac
    35221 gtcattggta tggttatgta atccaaataa tcctacaggt acatatttta atcatgagag
    35281 cttagattcg tttttatctc aagtacctcc acatgtacca gtaattatag atgaagctta
    35341 ttttgaattt gtgacagcag aggactaccc ggatacactt gctttgcaac aaaaatatga
    35401 caatgctttc ttattacgta cattttcaaa ggcgtatgga ttagcgggtt tacgtgtagg
    35461 atatgtggta gcaagtgaac atgcgattga aaaatggaac atcattagac caccatttaa
    35521 tgtgacacgt atatctgaat acgcagcagt tgcagcactt gaagatcaac aatatttaaa
    35581 agaggtaaca cataaaaata gtgttgaacg cgaaagattt tatcaattac ctcaaagtga
    35641 gtatttcttg ccaagtcaaa cgaattttat atttgtaaaa acaaagcggg taaatgaact
    35701 ttatgaagca cttttaaatg tagggtgtat tacgcgacca tttccaactg gtgttagaat
    35761 tacaattggt tttaaagaac aaaatgataa aatgttagaa gttttatcaa attttaaata
    35821 cgaatagtaa gtggggagtg ggacagaaat gatattttct caaaatttat ttcgtcgtcc
    35881 caccccaact tgcattgcct gtagaatttc ttttcgaaat tctctgtgtt ggggcccctg
    35941 actagaattg aaaaaagctt gttacaagcg cattttcgtt cagtcaacta ctgccaatat
    36001 aactttgtag agcattgaac attgatttat gtctcaagct caatgcagtg tgaatgatga
    36061 ggtgagagta ttcagtgtaa aaagcaacaa tagatgatat tgttttgtat caattgcttt
    36121 tttgctatac tgaatcaata ctgatatttt gaggagaaga ttaaaatgac ccgtaaatca
    36181 atcgcgattg atatggatga agtattggca gatacattag gagaaatcat tgatgctgtc
    36241 aattttagag cggatttagg tattaaaatg gaagctttga atggtcaaaa acttaaacat
    36301 gttattcctg aacatgatgg attaattaca gaagtattga gagaaccagg cttcttcaga
    36361 catcttaaag tgatgccaca tgcacaagaa gttgtgaaaa aattaactga acattatgat
    36421 gtatatattg ctacagcagc aatggatgta ccaacatcat ttagtgataa atatgaatgg
    36481 ttactagagt tctttccatt tttagatcct cagcattttg ttttttgtgg tagaaaaaac
    36541 atcgttaaag ctgattattt aatagatgac aatcctagac agcttgaaat ttttactggt
    36601 acaccgatta tgtttacagc agtgcataat attaatgatg atcgatttga acgcgtaaat
    36661 agctggaaag atgtagaaca gtatttttta gataatattg agaaataaaa tatatcactt
    36721 gaaaaatttc atgtagaaaa gatgatggat aggctataaa gtaattgtga ctgagatgaa
    36781 cttttatgtc ttagacacta caacactata ttggcagtag ttgactgcgg ggccccaaca
    36841 tagagaaatt ggattcccaa tttctacaga caatgcaagt tggcggggcc ccaacataga
    36901 gaaattggaa cgccaatttc tacagacaat gcaagttggg gtgggcccca acataaagaa
    36961 atactttttc tttagaaatt agtatttctt atgggagtgg gacataaatc aatgttctat
    37021 gctctacgaa gttatattgg cagtagttga ctgaacgaaa atgcgcttgt aacaagcttt
    37081 tttcaattct agtcaacctt gccggcgggg ccccaacaca gagaaattgg attcccaatt
    37141 tctacagaca atgcaagttg gggtgggacg acgaaataaa ttttgcgaaa atatcatttc
    37201 tgtcccactc cctcctattt ttaagtacac attagctttg actaatgata aagaatcgct
    37261 acataatcaa tcattagtcg ttctttatca tttccgtccc gctctcaata aatgttagtc
    37321 tatctcatta ttataaatcg gatgaatgtg ttaatctatg gcagattaca cgtcatccga
    37381 ttttttatag aatttgaaaa agacgcataa accactatga tttaaaatac aacatcaatc
    37441 attttagtgg catgcgccaa aattatatgt ctgtttttga aacagggtaa tagcttaaag
    37501 ctaataaaaa cgaatataag gtgcgttgaa tcttatgatt acactccaaa cctaatataa
    37561 tatcgggtca agatcattcc ggatgcttac aaatcattga cagtaagtaa ctgaatagca
    37621 tttggtataa cctcaatatc aataggtgtt tctaatgaaa tttcgccatc aatatcaact
    37681 ttcattgctg gatctgttgt aagtgaaatc tttttaccag gtatatgctc aataccttga
    37741 gtaatttcat tccaattcat gctatcacgc tttttaaaaa tatcatttaa aatactgaaa
    37801 ctttgttcat taaaaatgaa agtgttcagt tcaccatctt gaggagacaa atcagtcaat
    37861 ggtatacgac taccaccaat gaatggacca tttgctgtta gtatcatggt cgtttcgcca
    37921 gaatatgtct tatcatctat tgataattga taattaaatt gtgttggatt tagcagtgtt
    37981 ttgacagttg atccaatata actcaattta ccaaatatat cttttgaacc atcttgtacg
    38041 ttttcagcgt tttgaacaat gagacctaag ccaacaaagt tgagtgcata ttgattattt
    38101 attttaatta catcgtatgt accaacttgt gcagaaatca tttgttcact agcttgttta
    38161 tgattaggtg ctatatttag cgtttttgta aaatcattaa aagtaccgcc tggtaaaatg
    38221 ccaataggga gttgaaggtc atgtgacata acaccattta taagttcgtt aaccgtgcca
    38281 tcaccgccaa gaataaataa tatatctaca tcttttgcat agtttttagt tttgatttct
    38341 tggcaatatt taataatgtc accttcgttt tcactcaatt gaatagaaag atgcttacaa
    38401 attgaactta atgctgttgt aacttcccca ataccttgat taatattttt taatccactg
    38461 tgttcatggt aaaagaggac accatgtgta tatttatttt ccatagttta gcctactttc
    38521 taaaaattgg ttcattaaat atatataccc acttttaatt gttaatacca aaaatatgtt
    38581 tttaaataga gaaaatggta ataactgaca ttgatgtcta tagagtggga cgagaaaata
    38641 tagttatagc tgtctataac gagcatatta agcttttatt tatactgata tcttgaattt
    38701 aattaataga aacctataaa aaaacagtaa gccatttaaa tgacttactg ttttttgaat
    38761 taggccaaca atattaacgt atacctttca tcgctttgat gattaaaggt gagaatgcta
    38821 atacaattgt tgtaacaata attgcaacaa cacctaggaa aataaagtaa tttgtttgac
    38881 ctagtggttc tattaactta actaaagtac cattgattgc ttgtgcagaa gcgttagtta
    38941 agtaccaaat actcatcatt tgggcattaa atgctttagg tgctaactta acagcagcac
    39001 tattacccgt tggtgataag catagctcac cgataacaca aataatgtac gataaaataa
    39061 cccagttaac tgagaagttt gatgaacctg atgcataacc tacaatacca attagtatgt
    39121 atgacgcacc tgctaagaac gtaccaattg caaattttac tggcaggcta ggttgtttag
    39181 ttccaagctt ttgccataaa agtgaaataa ttggagctaa taataaaata aataatgggt
    39241 taattgattg gaagatcgct tcaccaaagt ttgttttcca accaaataag tttaatttca
    39301 tatctgaatg ttcaattcca tatatgttta atacattaga cccttgttct tgaatagccc
    39361 agaacaccat tccaagaata aataatggaa taaatgcttt aacacgagaa cgttcagtat
    39421 cagtgacatc tttacttcta ataattaaag tgaagtaaat gattggtaat gcaataccta
    39481 atactaaaac agtattacta actaagttaa atgataatga gttagttaat gcaccaataa
    39541 cgataattaa tacaattgct aagacaacac ttccgataat aagaccatac tttttctttt
    39601 cagctggtgt caatgggtta gtaggtttca taccaacgct acctaagttt ttgcggttga
    39661 aaagtacata ccatactaaa cctaatgcca taccaactgc tgcaatcaag aatccgccgt
    39721 ggaagttttt aacattaaca aagtgttgca aaataatagg tgataataat gcacccatat
    39781 taactgacat atagaaaata acaaaacctg catccatacg tctatcattt tcaggatata
    39841 aacggccaac gatatttgaa atgtttggct tcattaaacc tgaaccaata atgatgaaga
    39901 acattgatgt gaataagccg attaatgcaa atggtaagct taaacaaata tgtccgataa
    39961 taataaagac tgcacctaat aaagtagcgc ctctagtgcc tgtaattctg tcagcaatcc
    40021 atccgcctgg tattgatgtc atatagatta atgaaccata aactgacata attgacatag
    40081 ctgttgtttt atcaattcca aggccattat ctgttacggc aaagtacatg tagaaaatga
    40141 gtagggcacg catgccataa taactaaacc tttcccagaa ctctacaaag aagagtacgc
    40201 ctagtcctcg aggatgcccg aaaaatcctg tttgaggtat gtcttgaatt tgatttccat
    40261 gggagttttg ttgtgtcatg tatacatccc atcctttctt cccctaatac aatagtttaa
    40321 gtaaatttga ttgtgcctta tcaactaaat attccaacaa atcacaaaaa aataaaaata
    40381 ttgagaatat tctgttatta agcgcgcaca attaattaga gataatataa aaatatactt
    40441 attgacgtta aagtgcaata ggtttctata aaaatgttgt ttaattcgtg tactaatatt
    40501 cttttggtgt actttggtat aaaatgttat tttaatgtaa cctattatgt atgctaaatg
    40561 aaaaacacac caataagtta ggaaaatcaa cttattggtg tgtttattaa atgatacatt
    40621 taacgattat ctattttttc gggatataaa tcatgattca tcaaacgatg ctcagccatt
    40681 ttttcatatt tagaatttgg acgtccatag tttgtataag gatcaataga aattccacca
    40741 cgtggtgtga acttgcccca gacttcaata taatgtgggt ccataagctc tatcaaatca
    40801 ttcataataa tattcataca atcttcgtga aaatcaccgt gatttctgaa actaaataag
    40861 tataatttca aagattttga ttcaaccatt ttaacatttg gaatatatga aatatagata
    40921 gttgcaaaat ctggttgccc agtaattgga cataatgatg taaattctgg acagttgaat
    40981 tttacgaaat agtcacgacc ttgatgctta ttatcaaacg attctaatac atcaggacga
    41041 tagtcaaaat tgtaagtatt gtcttgattt cctaataaag ttatatcttg taattcatct
    41101 tgttgacggc catgtgccat ataaagcgct cctttaaatt tattttttta ttattttggc
    41161 gtctcggcgt gctttttcaa acatgtaata acttgcaccg ataataacga cgtaacctaa
    41221 tgttgcatag aaatctggag attctccgaa tagaacaaat ccaagtattg ctgtgaaaat
    41281 tatagatgca tacgtaaaaa tagaaatatc ttttgctgct gcaaaactat atgctaaagt
    41341 aacaccaatt tgacccacag cggcagctaa gccagcccct aatagataaa gtatttgcat
    41401 ctgactcatt ggttcataag tatatgcagt gaaaggtatt aaaacgatga cagaaaataa
    41461 ggagaagtaa aatactatag tatatggtgc ttctcttgaa ctaagtgctc gaacacatgt
    41521 atatgctgat gctgcaaaaa tacctgagaa taagccagct aatgatggaa tcatagatga
    41581 tgaaaattca ggtttcacta ttaaaagcat acctaaaata gcaattatca ttgctgtaat
    41641 ttgatacttc cttacctttt catgtaagaa aacaatgctt aataaaatcg tccagaaagg
    41701 attgagtttc attaatgaat cggcatcact aagtaccata tgatcaatgg cataaatatt
    41761 taacaataca ccaataagtc caagtgttga tcgtgttatt aataagggtt gacttgaaag
    41821 tctgccaaac attggctgat ggtatttata taaaaaaaat aatggaataa acattgctac
    41881 taagtttcgt gctaatgatt tttgaaaaac aggaaggtca cctgcaagtc tgaaaaacac
    41941 tgacataaaa ctgaaaccaa tagccgaaat taaaatggca atgatacctt ttactttagg
    42001 attcaatttt atcgcctctt ttatataaaa ttaacgtatt tatattagca taaaacaaca
    42061 tgttgtgcat aaatagttga aatttactat aaaaagacta taatagactg taccgaacaa
    42121 acgttctgtg tttatttgtc ggaataatag ggcattacac ttttatgaat gtttgtgtta
    42181 ttacataaaa caaatatcaa ttcagtatca agctaataag ctttttcttg atttctgttg
    42241 atacaattga gattgacaca gatttaaaaa aatcaagtga tatctactaa aaaatttttt
    42301 taaatttgtt caagtttttc taatttagta ttggtgccta gttggaacgt tttacgaaca
    42361 ttcgattaga aaatggcact ttaaatcata gtgtgtctta tgtataatga aacacataat
    42421 atagtgttgg tgaaacgaaa aagacacaat atcttgtgtt ttgtatgcaa atgctttatt
    42481 tatgaagaaa ttacatttaa aagtaattta acacagaaat ttaatagtta ttatcaatta
    42541 atagtcatat ttttagaaaa tgtactgagc aaatggaaga tat
//
LOCUS       DAPDIM010000017        41496 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000017 DAPDIM010000000
VERSION     DAPDIM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 41496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41496
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.017"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            139..441
                     /gene="gatC"
                     /locus_tag="RFE25_000983"
     CDS             139..441
                     /gene="gatC"
                     /locus_tag="RFE25_000983"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HDU2816072.1"
                     /translation="MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDS
                     ADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA"
     gene            443..1900
                     /gene="gatA"
                     /locus_tag="RFE25_000984"
     CDS             443..1900
                     /gene="gatA"
                     /locus_tag="RFE25_000984"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HDU2816073.1"
                     /translation="MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFL
                     ALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPI
                     YESTVMEKLHKENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAA
                     AVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTR
                     NVKDNAIVLEAISGADVNDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDV
                     KEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSK
                     EAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKV
                     FENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRP
                     IGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL"
     gene            1913..3340
                     /gene="gatB"
                     /locus_tag="RFE25_000985"
     CDS             1913..3340
                     /gene="gatB"
                     /locus_tag="RFE25_000985"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HDU2816074.1"
                     /translation="MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAY
                     PGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGEN
                     GYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSP
                     KEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFN
                     YVRKGLEYEEKRQEEELLNGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIV
                     PLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHG
                     ADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPE
                     LAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQ
                     IMKASKGQANPQLVNQLLKQELDKR"
     gene            3380..3526
                     /locus_tag="RFE25_000986"
     CDS             3380..3526
                     /locus_tag="RFE25_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816075.1"
                     /translation="MIADLDAIEGLFISIEVILLLTLFIVHVNGKNINFINALALIIL
                     RQTV"
     gene            4164..5111
                     /locus_tag="RFE25_000987"
     CDS             4164..5111
                     /locus_tag="RFE25_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDU2816076.1"
                     /translation="MRKRARIIYNPTSGKELFKRELPDALIKLEKAGYETSAYATEKI
                     GDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRAL
                     HIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPF
                     AYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGY
                     FTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGG
                     KLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE"
     gene            5192..6553
                     /gene="rlmD"
                     /locus_tag="RFE25_000988"
     CDS             5192..6553
                     /gene="rlmD"
                     /locus_tag="RFE25_000988"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDU2816077.1"
                     /translation="MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIE
                     YKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVI
                     NLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
                     SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTN
                     GKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDST
                     FKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYG
                     VEVVPSSIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDE
                     TFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALF
                     NLK"
     gene            6723..7253
                     /locus_tag="RFE25_000989"
     CDS             6723..7253
                     /locus_tag="RFE25_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3267 domain-containing protein"
                     /protein_id="HDU2816078.1"
                     /translation="MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQ
                     NIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKW
                     QFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYV
                     QQDEDSIYLYHQKPTQ"
     gene            7500..8570
                     /gene="dinB"
                     /locus_tag="RFE25_000990"
     CDS             7500..8570
                     /gene="dinB"
                     /locus_tag="RFE25_000990"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDU2816079.1"
                     /translation="MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVS
                     TASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPM
                     SLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKP
                     DGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFG
                     KRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERL
                     NKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRL
                     IGVTVGNLEQSTYKNMTIYDFI"
     gene            complement(8638..9192)
                     /locus_tag="RFE25_000991"
     CDS             complement(8638..9192)
                     /locus_tag="RFE25_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDU2816080.1"
                     /translation="MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNP
                     QDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQ
                     NIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITF
                     RLLKNYENLTYVTNIYGKNLKDKG"
     gene            9408..9500
                     /locus_tag="RFE25_000992"
     CDS             9408..9500
                     /locus_tag="RFE25_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816081.1"
                     /translation="MTKNTIISLENEKTQINDSENESSDLRKAK"
     gene            complement(9582..10082)
                     /gene="ftnA"
                     /locus_tag="RFE25_000993"
     CDS             complement(9582..10082)
                     /gene="ftnA"
                     /locus_tag="RFE25_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-type ferritin FtnA"
                     /protein_id="HDU2816082.1"
                     /translation="MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFI
                     QQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFY
                     NLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGA
                     RTFDEE"
     gene            10374..11687
                     /gene="murT"
                     /locus_tag="RFE25_000994"
     CDS             10374..11687
                     /gene="murT"
                     /locus_tag="RFE25_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HDU2816083.1"
                     /translation="MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDVLRKLA
                     EQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKT
                     KIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKL
                     LLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQ
                     IGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLR
                     ELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEK
                     VYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPI
                     IVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS"
     gene            11689..12420
                     /locus_tag="RFE25_000995"
     CDS             11689..12420
                     /locus_tag="RFE25_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDU2816084.1"
                     /translation="MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINE
                     TEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGK
                     KYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTL
                     GHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPK
                     EIDNEAEIQAKQVLIDRANRQKKSR"
     gene            12506..12616
                     /locus_tag="RFE25_000996"
     CDS             12506..12616
                     /locus_tag="RFE25_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816085.1"
                     /translation="MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT"
     gene            12645..13058
                     /locus_tag="RFE25_000997"
     CDS             12645..13058
                     /locus_tag="RFE25_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816086.1"
                     /translation="MKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATF
                     EDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDS
                     GLRHSNMATESGISLRINIAKSDFTKFINELASLY"
     gene            complement(13489..14475)
                     /locus_tag="RFE25_000998"
     CDS             complement(13489..14475)
                     /locus_tag="RFE25_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDU2816087.1"
                     /translation="MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVV
                     TIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKL
                     QVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEE
                     KLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYH
                     KKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKD
                     IFYDGTFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA"
     gene            15006..15764
                     /gene="map"
                     /locus_tag="RFE25_000999"
     CDS             15006..15764
                     /gene="map"
                     /locus_tag="RFE25_000999"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDU2816088.1"
                     /translation="MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAK
                     ELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYY
                     ADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLK
                     VIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNE
                     WAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE"
     gene            15981..16367
                     /locus_tag="RFE25_001000"
     CDS             15981..16367
                     /locus_tag="RFE25_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816089.1"
                     /translation="MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITK
                     KEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIET
                     QIQQTSTEKIATEKTSYLINYMNAVA"
     gene            16382..17083
                     /locus_tag="RFE25_001001"
     CDS             16382..17083
                     /locus_tag="RFE25_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HDU2816090.1"
                     /translation="MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLV
                     YVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKV
                     VATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTI
                     VVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVN
                     IYVSTFIGDVEVIYR"
     gene            17080..18123
                     /locus_tag="RFE25_001002"
     CDS             17080..18123
                     /locus_tag="RFE25_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDU2816091.1"
                     /translation="MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIF
                     GIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYS
                     ETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
                     QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLG
                     EGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVE
                     LFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIE
                     VKAPLNKEDSYDD"
     gene            18113..18742
                     /gene="vraR"
                     /locus_tag="RFE25_001003"
     CDS             18113..18742
                     /gene="vraR"
                     /locus_tag="RFE25_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator VraR"
                     /protein_id="HDU2816092.1"
                     /translation="MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKA
                     HELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSY
                     ILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
                     KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ"
     gene            complement(18855..20072)
                     /locus_tag="RFE25_001004"
     CDS             complement(18855..20072)
                     /locus_tag="RFE25_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDU2816093.1"
                     /translation="MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQF
                     QSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMF
                     PMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILA
                     IWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVI
                     SHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFT
                     SIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQR
                     SVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDK
                     NIKDKIVDKLKKD"
     gene            complement(20350..20625)
                     /locus_tag="RFE25_001005"
     CDS             complement(20350..20625)
                     /locus_tag="RFE25_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDU2816094.1"
                     /translation="MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTR
                     KPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR"
     gene            complement(20632..21096)
                     /locus_tag="RFE25_001006"
     CDS             complement(20632..21096)
                     /locus_tag="RFE25_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HDU2816095.1"
                     /translation="MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSW
                     NLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKG
                     QLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG"
     gene            21243..21443
                     /locus_tag="RFE25_001007"
     CDS             21243..21443
                     /locus_tag="RFE25_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1128 family protein"
                     /protein_id="HDU2816096.1"
                     /translation="MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQS
                     RERLSPSEVTAIADALGQLRHG"
     gene            21446..22702
                     /locus_tag="RFE25_001008"
     CDS             21446..22702
                     /locus_tag="RFE25_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDU2816097.1"
                     /translation="MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTH
                     LIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAA
                     NLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKR
                     VYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYV
                     SEGTDLTVGLAKNHIWEDATSYVNGEEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPL
                     SYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISN
                     RNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSS
                     DLTIYGIFEDGSKELVFENGNWASTF"
     gene            22792..23322
                     /locus_tag="RFE25_001009"
     CDS             22792..23322
                     /locus_tag="RFE25_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDU2816098.1"
                     /translation="MTNQDRPMKSMSESKCYKNRQVFPQDTNHHHTMFGGTLMANIDE
                     IAAITAMKHAGAQVVTASTDSVDFLKPIKTGDILQYVAMVSYAGTSSMEVVVQIRIDD
                     VFNNKHDLAALSYLTFVALDDEGKPKHVPGVYPEDDVEKWFYDTAPQRVERRKARRIE
                     SKQTIEYLAQVQHIRD"
     gene            complement(23582..24733)
                     /gene="yfkAB"
                     /locus_tag="RFE25_001010"
     CDS             complement(23582..24733)
                     /gene="yfkAB"
                     /locus_tag="RFE25_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM/CxCxxxxC motif protein YfkAB"
                     /protein_id="HDU2816099.1"
                     /translation="MNSVKLKQPVSIYNDPWESYNDVKEHGQLTLSNIEFTTTNLCNM
                     RCSHCAVGYTLQTVDPEPLDMDLIYRRLDEIPNLRTMSITGGEPMFSKKSIRNVVKPL
                     LKYAHHRGIYTQMNSNLTLPQDRYLDIAEYIDVMHISHNWGTTDEFANVGFGAMKKQP
                     PLKAKLKLYEQMISNARTLSEQGMFVSAETMLNQSTLPHLRKIHQEVVHDMKCSRHEI
                     HPMYPADFASQLNVLTLAEMKKTIHDILDFRDEDIWMLFGTLPVFPCLKDDEDQKLLS
                     RLRNANNVTTRNDPDGRSRLNVNVFTGNVIVTDFGDETGTISNIQKDKLTDVFDKWLS
                     SDLAKSLNCHCSEFSCLGPNVLVKNMYYPNMDFKDNERHMHKQPQIIQF"
     gene            24957..25118
                     /locus_tag="RFE25_001011"
     CDS             24957..25118
                     /locus_tag="RFE25_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816100.1"
                     /translation="MNEQQTIEQIKARLNKFIEDIDHVNPDEVRVEDIDEWIGLLDQL
                     EEKVKLVSK"
     gene            25249..25764
                     /locus_tag="RFE25_001012"
     CDS             25249..25764
                     /locus_tag="RFE25_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDU2816101.1"
                     /translation="MTKKVAIILANEFEDIEYSSPKEALENAGFNTVVIGDTANSEVV
                     GKHGEKVTVDVGIAEAKPEDYDALLIPGGFSPDHLRGDTEGRYGTFAKYFTKNDVPTF
                     AICHGPQILIDTDDLKGRTLTAVLNVRKDLSNAGAHVVDESVVVDNNIVTSRVPDDLD
                     DFNREIVKQLQ"
     gene            26104..26913
                     /gene="sgtB"
                     /locus_tag="RFE25_001013"
     CDS             26104..26913
                     /gene="sgtB"
                     /locus_tag="RFE25_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional peptidoglycan glycosyltransferase
                     SgtB"
                     /protein_id="HDU2816102.1"
                     /translation="MKRSDRYSNSNEHFEHMKHEPHYNTYYQPVGKPPKKKKSKRILL
                     KILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPEYVKGAFISMEDE
                     RFYNHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNDRSFTRKVKELFVA
                     HRVEKQYNKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSTTMSHITVLQSAI
                     LASKVNAPSVYNINNMSENFTQRVSTNLEKMKQQNYINETQYQQAMSQLNR"
     gene            27173..27991
                     /gene="recX"
                     /locus_tag="RFE25_001014"
     CDS             27173..27991
                     /gene="recX"
                     /locus_tag="RFE25_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDU2816103.1"
                     /translation="MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQ
                     LEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCY
                     REKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDD
                     IIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQ
                     RDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE"
     gene            27969..28283
                     /locus_tag="RFE25_001015"
     CDS             27969..28283
                     /locus_tag="RFE25_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhH family protein"
                     /protein_id="HDU2816104.1"
                     /translation="MEQKKLSEMSEPELRHEIQLYKEKMRKAEMNGILNEYDVYQSKV
                     IVAESYLVDRKKIEIGKIYKLTDGSNQYFKVERLKGIFAWGFRFNSDEPEEGLPIALL
                     QL"
     gene            28298..29815
                     /locus_tag="RFE25_001016"
     CDS             28298..29815
                     /locus_tag="RFE25_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816105.1"
                     /translation="MGSSIVLKLLKVTHYYRNKQNKKWYLPFGYDAEDIDLNNISLHI
                     YQGEALGIIGEPESSKALVGQLLAGAIKPDKGKVVCTEDLFYGYIEDQSLIHQTVEAY
                     TAQLVQLFPYEINDHKAEQIIQYAHLGDYKTKPVNHISKAAYAQLLLSIARSSKSNII
                     ILNHVIDYLTPQFMERAIELTNDYIENNLTIVSIGDDIDKISQVSNYIAWFSHGQLRM
                     EGSLKQVIPSFKEHERDRLSLNSKEEIENFDLDWKKNRTRIPEMTYNFKRVERYNHAK
                     PPKFLVRFWTLASGTILGLALMMLLIFNNIGIISITDFTNRATMQNENKDPYGEKLAY
                     GIAFNGSVDMQGDKQVTIPKYSVVTITGENSKNYRVTADNKTYYVSKDKLEYFNPAGL
                     YQTHSFKKLAPYMKSNYSNYYAYFNSQLHKKHSSVIKTLVPDDDNRFVASVTQQPIQL
                     LFNDNNQLYGFVYPIVDKKELKDKFNINNNIWITKVGNGYCIANLKEDKWIYIEL"
     gene            29824..30660
                     /locus_tag="RFE25_001017"
     CDS             29824..30660
                     /locus_tag="RFE25_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816106.1"
                     /translation="MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIAS
                     ETLFSFSHLTDVKEVRWLFRIIALIVFAVLMFTIYISYHHYMNDFLVTKLFNISAATP
                     VVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLL
                     TEKINIIFYGVCVLCILLLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISS
                     MENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSNDSTDEADT
                     SS"
     gene            complement(30921..31898)
                     /locus_tag="RFE25_001018"
     CDS             complement(30921..31898)
                     /locus_tag="RFE25_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDU2816107.1"
                     /translation="MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGD
                     TVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTNPFHVWMWAQLAVFL
                     HVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVIGLHPFAVFFP
                     IIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDY
                     VGKAYGRNVVFSDKVERQTLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTE
                     IRLIDLRYLKNDHYSFVAIAHVTNDNVIDHSYIGWVFTEDKLQRKLYAK"
     gene            32050..33087
                     /gene="mutY"
                     /locus_tag="RFE25_001019"
     CDS             32050..33087
                     /gene="mutY"
                     /locus_tag="RFE25_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDU2816108.1"
                     /translation="MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQ
                     VKTVIDYYLRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVYDKYEG
                     LVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQST
                     RKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKL
                     PVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFESEHARRKMTEKI
                     GHDIQPVETPIFELKHQFTHLTWKIKVYAASGAINIETLPDDMIWFNLSDRDQYTFPV
                     PMSKIYQFING"
     gene            33390..33932
                     /locus_tag="RFE25_001020"
     CDS             33390..33932
                     /locus_tag="RFE25_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDU2816109.1"
                     /translation="MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGG
                     NDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEAL
                     KYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKG
                     PFAPDFIKVWKERYKKIRQY"
     gene            34223..35959
                     /locus_tag="RFE25_001021"
     CDS             34223..35959
                     /locus_tag="RFE25_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAV1866 family putative multidrug efflux ABC
                     transporter"
                     /protein_id="HDU2816110.1"
                     /translation="MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGV
                     VNNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYN
                     HLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLD
                     VKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAI
                     EDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSIT
                     VGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIE
                     IKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYD
                     VTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEA
                     AKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSAL
                     DLKNESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQ
                     GAYEHLYSIQNL"
     gene            35968..36059
                     /locus_tag="RFE25_001022"
                     /pseudo
     CDS             35968..36059
                     /locus_tag="RFE25_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500499.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36149..37243)
                     /locus_tag="RFE25_001023"
     CDS             complement(36149..37243)
                     /locus_tag="RFE25_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014667727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDU2816111.1"
                     /translation="MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQP
                     SIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVAT
                     LASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNI
                     SSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNR
                     KKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASL
                     SKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHH
                     LEHLDRIRISFFTYHRSDADIEIVEEDFDL"
     gene            complement(37536..38825)
                     /locus_tag="RFE25_001024"
     CDS             complement(37536..38825)
                     /locus_tag="RFE25_001024"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500497.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDU2816112.1"
                     /translation="MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHG
                     AYLYDVDGNKFIDYLQAYGPIIAGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKL
                     RDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGP
                     SQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMP
                     QPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPI
                     GGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQL
                     EEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQG
                     INLAPSKFEAWFLTTEHTEEDIQQTLKAADYAFSQMK"
     gene            38906..39361
                     /gene="bcp"
                     /locus_tag="RFE25_001025"
     CDS             38906..39361
                     /gene="bcp"
                     /locus_tag="RFE25_001025"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDU2816113.1"
                     /translation="MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTC
                     TTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETG
                     VYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG"
     gene            39367..40317
                     /locus_tag="RFE25_001026"
     CDS             39367..40317
                     /locus_tag="RFE25_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDU2816114.1"
                     /translation="MKVVGLNRMREVETELQQRFSDLDFKFYKKASEIPESDLADLDI
                     LVGYDGGINEAFLQRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEY
                     ILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFN
                     MNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIIINALPETQETIHLLKKKHFELMK
                     DEALFINIGRGSIVKEALLIEVLKSKVIRHAYLDVFENEPLKPNHELYELENVTITAH
                     ITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY"
     gene            40414..40860
                     /gene="perR"
                     /locus_tag="RFE25_001027"
     CDS             40414..40860
                     /gene="perR"
                     /locus_tag="RFE25_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HDU2816115.1"
                     /translation="MSVEIESIEHELEESIASLRQAGIRITPQRQAILRYLISSHTHP
                     TADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIIC
                     EQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK"
BASE COUNT        14985 a         5872 c         7299 g        13340 t
ORIGIN      
        1 taaaaaatga tttgataaac gaatgataat gtttatacag tttatatgaa attaaagtag
       61 cacctcataa atacttagat ttttaattgg aaatttgata caatttagtg atgaatgact
      121 taaaggaggc ttttattaat gacaaaagta acacgtgaag aagttgagca tatcgcgaat
      181 cttgcaagac ttcaaatttc tcctgaagaa acggaagaaa tggccaacac attagaaagc
      241 attttagatt ttgcaaaaca aaatgatagc gctgatacag aaggcgttga acctacatat
      301 cacgttttag atttacaaaa cgttttacgt gaagataaag caattaaagg tattccgcaa
      361 gaattagctt tgaaaaatgc caaagaaaca gaagatggac aatttaaagt gcctacaatc
      421 atgaatgagg aggacgcgta agatgagcat tcgctacgaa tcggttgaga atttattaac
      481 tttaataaaa gacaaaaaaa tcaaaccatc tgatgttgtt aaagatatat atgatgcaat
      541 tgaagagact gatccaacaa ttaagtcttt tctagcgctg gataaagaaa atgcaatcaa
      601 aaaagcgcaa gaattggatg aattacaagc aaaagatcaa atggatggca aattatttgg
      661 tattccaatg ggtataaaag ataacattat tacaaacgga ttagaaacaa catgtgcaag
      721 taaaatgtta gaaggttttg tgccaattta cgaatctact gtaatggaaa aactacataa
      781 agagaatgcc gttttaatcg gtaaattaaa tatggatgag tttgcaatgg gtggttcaac
      841 agaaacatct tatttcaaaa aaacagttaa cccatttgac cataaagcag taccaggtgg
      901 ttcatcaggt ggatctgcag cagcagttgc agctggctta gtaccattta gcttaggttc
      961 agacacaggt ggttcaatta gacaaccggc tgcatattgt ggcgttgtcg gtatgaaacc
     1021 aacatacggt cgtgtatctc gatttggatt agttgctttt gcatcttcat tagaccaaat
     1081 tggtccattg actcgaaatg taaaagataa tgcaatcgta ttagaagcta tttctggtgc
     1141 agatgttaat gactctacaa gtgcaccagt tgatgatgta gactttacat ctgaaattgg
     1201 taaagatatt aaaggattaa aagttgcatt acctaaagaa tacttaggtg aaggtgtagc
     1261 tgatgacgta aaagaagcag ttcaaaacgc tgtagaaact ttaaaatctt taggtgctgt
     1321 cgttgaggaa gtatcattgc caaatactaa atttggtatt ccatcatatt acgtgattgc
     1381 atcatcagaa gcttcgtcaa acctttctcg ttttgacgga attcgttatg gttatcattc
     1441 taaagaagct cattcattag aagaattata taaaatgtca agatctgaag gtttcggtaa
     1501 agaagtaaaa cgtcgtattt tcttaggtac atttgcatta agttcaggtt actacgatgc
     1561 ttactataaa aaatctcaaa aagttagaac attgattaaa aatgactttg ataaagtatt
     1621 cgaaaattat gatgtagtag ttggtccaac agcgcctaca actgcgttta atttaggtga
     1681 agaaattgat gatccattaa caatgtatgc caatgattta ttaacaacac cagtaaactt
     1741 agctggatta cctggtattt ctgttccttg tggacaatca aatggccgac caatcggttt
     1801 acagttcatt ggtaaaccat tcgatgaaaa aacgttatat cgtgtcgctt atcaatatga
     1861 aacacaatac aatttacatg acgtttatga aaaattataa ggagtggaaa tcatgcattt
     1921 tgaaacagtt ataggacttg aagttcacgt agagttaaaa acggactcaa aaatgttttc
     1981 tccatcacca gcgcattttg gagcagaacc taactcaaat acaaatgtta tcgacttagc
     2041 atatccaggt gtcttaccag ttgttaataa gcgtgcagta gactgggcaa tgcgtgctgc
     2101 aatggcacta aatatggaaa tcgcaacaga atctaagttt gaccgtaaga actatttcta
     2161 tccagataat ccaaaagcat atcaaatttc tcaatttgat caaccaattg gtgaaaatgg
     2221 atatatcgat atcgaagtcg acggtgaaac aaaacgaatc ggtattactc gtcttcacat
     2281 ggaagaagat gctggtaagt caacacataa aggtgagtat tcattagttg acttgaaccg
     2341 tcaaggtaca ccgctaattg aaatcgtatc tgaaccagat attcgttcac ctaaagaagc
     2401 atatgcatat ttagaaaaat tacgttcaat tattcaatac actggtgtat cagacgttaa
     2461 gatggaagag ggatctttac gttgtgatgc taacatctct ttgcgtccat atggtcaaga
     2521 aaaatttggt actaaagccg aattgaaaaa cttaaactca tttaactatg tacgtaaagg
     2581 tttagaatat gaagaaaaac gccaagaaga agaattgtta aatggtggag aaatcggaca
     2641 agaaacacgt cgatttgatg aatctacagg taaaacaatt ttaatgcgtg ttaaagaagg
     2701 ttctgatgat taccgttact tcccagagcc tgacattgta cctttatata ttgatgatgc
     2761 ttggaaagag cgtgttcgtc agacaattcc tgaattacca gatgagcgta aggctaagta
     2821 tgtaaatgaa ttaggtttac ctgcatacga tgcacacgta ttaacattga ctaaagaaat
     2881 gtcagatttc tttgaatcaa caattgaaca cggtgcagat gttaaattaa catctaactg
     2941 gttaatgggt ggcgtaaacg aatatttaaa taaaaatcaa gtagaattat tagatactaa
     3001 attaacacca gaaaatttag caggtatgat taaacttatc gaagacggaa caatgagcag
     3061 taaaattgcg aagaaagtct tcccagagtt agcagctaaa ggtggtaatg ctaaacagat
     3121 tatggaagat aatggcttag ttcaaatttc tgatgaagca acacttctaa aatttgtaaa
     3181 tgaagcatta gacaataacg aacaatcagt tgaagattac aaaaatggta aaggcaaagc
     3241 tatgggcttc ttagttggtc aaattatgaa agcgtctaaa ggtcaagcta atccacaatt
     3301 agtaaatcaa ctattaaaac aagaattaga taaaagataa tttaaatcat caaactatga
     3361 agatttaaaa aataaaccct tgattgctga cttagatgca atcgagggtt tatttatatc
     3421 tatagaagtc atattacttt taactttatt cattgtacat gttaatggta aaaatattaa
     3481 ttttattaat gcgttagctt taattatatt aaggcaaact gtataataaa aaggtataaa
     3541 acatttttgt ataaagacaa cattatattt acaacatcat tttaaaggta aaatagcata
     3601 actgacgaag tctatataat gaagaacggc aaaaaatgct gaataaataa caagctttgt
     3661 acatattgag atagtatttg tttaagatac aagttggtct ttaacgatat taagaatgat
     3721 gaaataagac tgagcctggg tcataaattc aatgtcctag gcactacaat gttatattgg
     3781 cagtagttga ctgaaagaaa atacgcttgt aacaagcttt tttcaattct agtggggccc
     3841 caacatagaa gctgactttc tgtcagctta caataatgtg caagttggcg gtgccccaac
     3901 atagaagctg actttctgtc agcttacaat aatgtgcaag ttggcggtgc cccaacatag
     3961 aagctgactt tctgtcagct tacaataatg tgcaagttgg ggtggggccc caaacaaaga
     4021 gaatttcgaa aggaaattct acagacaatg caagttgggg tagaacgaaa taaattttgt
     4081 taaatattat ttctgtccca ctccctatta gacgaaacaa agatgaagtt aaaatatatg
     4141 aattttaagt agagggataa gatatgagga aacgtgctag aatcatttat aacccgacat
     4201 caggtaaaga gctatttaaa agagaattac ctgatgcctt aataaaatta gaaaaagcgg
     4261 gatatgaaac gagtgcatat gcaaccgaga aaataggtga tgccacactt gaagcagaaa
     4321 gagctatgca tgaaaattat gatgtattaa tcgctgcagg tggtgatgga acattaaatg
     4381 aagtagttaa tggtatcgca gaaaagccta atcgtcctaa gctaggtgtc attcctatgg
     4441 gtactgttaa tgactttgga cgtgcattgc atatacctaa tgacatcatg ggggcacttg
     4501 atgtcatcat tgaaggtcat tctactaaag tagatattgg taaaatgaat aatcgatact
     4561 ttattaattt agctgcaggc ggacaattga cgcaagtctc ttatgaaaca ccgagtaaat
     4621 tgaaatctat tgttggtcca tttgcttatt acatcaaagg tttcgaaatg ttacctcaaa
     4681 tgaaagctgt agatttaaga attgaatatg atggtaatgt tttccaagga gaagcattat
     4741 tattcttttt aggtttaaca aattcaatgg caggatttga aaaattagtg ccggacgcta
     4801 agttagatga cggctatttt acgttaatta tagttgaaaa atcaaacctt gcagaacttg
     4861 gtcatattat gactttagct tcaagaggag aacatactaa gcatcctaaa gttatttatg
     4921 aaaaagcaaa ggcaattaat atttcatcat tcacagactt acaactaaat gtagatggag
     4981 aatatggtgg taaattacca gcgaatttct taaatctaga acgtcatata gatgtctttg
     5041 cacctaatga tattgtaaat gaagagttaa taaataatga tcatgttgat gacaatttaa
     5101 tcgaagaata aacagaaata gtgaaatata taatggcagg ttaggaagcg cataattttg
     5161 ttcctaacct gttcattttg gaggtaaaat tttgcaagca atagctaaaa atgacataaa
     5221 aacgggaaca gttgttgatt taacgcatga aggccatggt gttgtaaaaa tagatcgctt
     5281 tcctattttc ataccacaag ctttaattaa tgaacaaatt gaatataaaa ttatcaaagt
     5341 aaaaaagaac tttgcgatag gtaagttgct taatataaat acgagaagtg agaatcgtgt
     5401 tgcaccgcca tgtatatatt atgaacgttg tggtgggtgc caacttcaac acttatcata
     5461 cgaagcacaa cttgaaatga aaaaggaaca agtgattaat ttgtttcagc gaaaagcgca
     5521 ttttgataat tctaagatta acgatacagt tggcatgaca gatccttgga gatatcgaaa
     5581 caagtcccag attccagttg gtaagaatga acagaatgaa gttattatgg gcttttatcg
     5641 tcaaagaagc catgacatta ttgacatgga aagttgttta atacaagatt cacaacatca
     5701 agaagtgatg aatgaagtta aatctatttt aaaagattta aatgtaagta tttatcaaga
     5761 acaattgaaa aaaggtttaa tgagacattt ggttgtaaga acaggatatc atacagacga
     5821 aatgatgatt atttttgtaa ctaatggtaa aaagtggcca caaaaaaatg ctgttgttga
     5881 gaagatatta gatgcatttc ctaatgtgac aagcattaaa caaaacatta atgatagcca
     5941 ctctaatgtt attatgggac gtcaatctat aacgctatat ggtaaagata caattattga
     6001 tcaattaaca gatagtacat ttaaaataag tgatcagtca ttctaccaaa ttaattctga
     6061 acaaacagag aaattatata ataaagcaat tgagtatgcg caattgacag gtaatgaagt
     6121 tgtattagat acctattgtg gtattggaac aatagggcta tatatggcac cacatgcaaa
     6181 acatgtatac ggtgttgaag tagtaccttc ttcaattgaa gacgcacaac aaaatgcgac
     6241 tataaaccaa tgcaataata caacttttgt ctgtgggaaa gctgaagaag ttattttaca
     6301 atggaaagca caagggatta aaccagatgt tgtaatggtt gatccgccaa gaaagggctg
     6361 tgacgaaacg tttattcaga ctttgcttac attagaacct aagcgtattg tctatatttc
     6421 atgtaatccc gcaacacagc aacgtgatgc attattatta gctgaaaaat atcaacttga
     6481 agaggtaaca ccggtagata tgtttccaca aacaacacat gttgagacag tggcattatt
     6541 caatttgaaa tagcgcacat gatttgagat aaaatttcgc cttaataagt gaagaaagaa
     6601 gtcgtatatt aaaattttat tacagccaat ttactttctt gatatgaact ttttaaatta
     6661 aatgtgacat tgtatactat atttaaagaa gaataagaat gtcatgatcg ggagggttgg
     6721 taatgcataa aattgattta acgacaaata attttcaaat gcgaaggttt attatcttgc
     6781 aacttgttat tgcgttattc gtgattttat ttacgtataa gtgggcgtta ggtgtcacag
     6841 cggttgtcga tcaaaatatc atcatcaatc ttgtatatgg gtttgctgga ttcattattt
     6901 tattgatttt acatgaactt atccatagag cattatttct tttatttaaa aaagatagca
     6961 aacctatgtt taatataaaa aaagacagaa tcttattcca aacagcagat gcttgcttca
     7021 acaaatggca attctcaatt attatgctgt caccactaat cttattaagt actggcttgc
     7081 ttattttaat taaggtattt ggttattcat cacttatttt tatgtttagt atgcataccg
     7141 cttattgctt tatagatatt ctgcttgttg cattaacaat atctagtagt tttaaatatg
     7201 ttcaacaaga tgaagatagt atttatttgt atcatcaaaa gccgactcaa taataaattt
     7261 taatatgata ataccaacaa aatgaatttg cttgaattat ttcagattac ctatgttttc
     7321 ttactcaatc gtcttcatca tcatgcttaa atagcaattg attttataac aacttgtagt
     7381 tatctcaata tagttatcgc taagtgcaag atttatgtaa aaaaatcgta cacagcgtat
     7441 aattatgttg agatattttt gtgcgttata aaagtaaaaa ttagtaggga ggtgagcact
     7501 tgactgagag acgaattatt catatagata tggactattt ttttgcacaa gtcgaaatga
     7561 gagataaccc caaattgaaa gggaaaccag tcattgttgg tggtaaagca agcagtaggg
     7621 gtgttgtctc tacggcatcc tatgaagcac gaaaatacgg cgtccattca gcaatgccta
     7681 tgtcacaagc gcataaatta tgtccaaatg gatactttgt cacaagtaat tttggtgctt
     7741 accgagaaac atctgcgcag attatgtcta ttttccgaag ttatacagat aaggtagaac
     7801 cgatgtcatt ggatgaagcg tatttagata ttacagaatt agtgagacca gaccttcctg
     7861 cttcgaaaat tgctcagtat attagaaaag atattctaga gcagacacat ttaacagcat
     7921 ctgcaggtgt ttcttataac aaatttttag ctaaattagc gagtggtatg aataaacctg
     7981 atggtttgac tgtgattgat tatcaaaatg tccatgatat tttgatgaca ttggatattg
     8041 gagattttcc aggcgtaggt aaagcttcca aaaaagtaat gcatgataat ggtattttta
     8101 acggtagaga tttatatgag aaaacggaat ttgaattaat acgtttgttt ggaaaaagag
     8161 gtcggggttt atataacaag gcacgcggta ttgaccatag tgaagtgaaa tcatcaagag
     8221 taagaaaatc agtagggact gaacgcacat ttgcaacaga cgtgaatgat gatgaagaga
     8281 ttttaagaaa agtatgggaa ttgtcaggta aaacagctga acgtctaaat aaattacaga
     8341 agtcagctaa aactgtaacg gttaaaatta aaacttatca atttgaaacg ctatctaaac
     8401 agatgagttt aagagattcg gttagttctg aagaagatat ttataatatt gcatatttac
     8461 tttataacga tttaaaagac ccagatgtac caattcgact tattggtgtc actgtaggta
     8521 atttagaaca atcaacttat aaaaatatga cgatatatga ctttatataa aataaagctc
     8581 cctgcaaagt ttacattttt acaatgctta cttttgaagg gagtatttta tttagtccta
     8641 gcctttatct tttagatttt taccataaat attagttaca tatgttaaat tttcataatt
     8701 tttcagtagc ctaaaagtaa tcattgcgca tgctttggca tcattcaatg catcatgatg
     8761 accatgaaaa tctaattgat aaaactccat catatgtttt aaaccgtatc gatacgaatc
     8821 aacggttctt ttagcaagtt gataactaca aaagtaagtt aaatttggag ttggtaaacc
     8881 aatattttga atgctttgat gtaagacgtt catatcaaat gccgcgttat gtgcgacaac
     8941 aggtaaatct gcaataaatt gcatcatata tggaaatacg tagtcaaacg taggtgcatt
     9001 ttcaacatct tctggttgta tgccatgaac tttaatattt tgttgtgaaa aatagtcttg
     9061 cggattcaca agagtatgaa atgtttctgt tatttgacta tcaatgactt taaccattcc
     9121 gacagaacaa atacttgtac gtttaccatt tgctgtttca aaatcaagtg caacaaacgc
     9181 atcttgtatc atgtagtcaa tcctttcaat taattaaatg tatatattaa tagactttta
     9241 gtcatttgct tacaaacgat acataatatt atacgtgaag gtataacgtg aaatctatca
     9301 tttggatgta actctgatta aaaagtaaat gatgatatgc tttaaaatcg gtcaaattaa
     9361 ttcaacatca aatttagagt tattaacatt agtagtttaa aaaataaatg actaaaaata
     9421 caataattag ccttgaaaat gaaaaaacgc agatcaatga ttcagaaaat gaatctagtg
     9481 atctccgtaa agcaaaataa tatagacatt gggttattgt aagtgaccca aatgcctatc
     9541 atgtcgtatg atatttatct gtctattgta gtgatgttta attattcttc gtcgaatgta
     9601 cgagcgccaa gttctttttc gtaaagatat aatgcattgc tgtcatcgcc gatacgagtt
     9661 aaataattga tgtgagtttc aaacattgat tcttcttcga cttgttcatc taagaaccag
     9721 tttaagaatg agatagttgc ataatcttta tcttgacgag cgatttcaga taagttatag
     9781 aaacgtcttg ttacttcttg ttcttgagat aagctgtctt tgaaagtttc tagtatgctt
     9841 gaaaagtcaa tttttggtgc tgaaactgct ctgaattctg catgtgcacc tctgtcgtta
     9901 atatagttat aaatcttttg tccatggaaa cgttcttctt tagcttgttg aatgaagaag
     9961 tttgcaaatc cttcgtacga ttctttatca cagtatgctg ccattgccat atatgcgtgt
    10021 gctgcaaagt actcatggtt catttgatca tttaatgctt ctaataaatt tttacttaac
    10081 attttgatac acctcttatt tgtaaattaa aattactatg aattaaactt agtataacaa
    10141 actcattctc aattgtaaat aataataatt ataatttaat accttatttt agcactctaa
    10201 ttgagaaaat gtatcattta gcgatattta attgagaata aatatcattt ttaattatct
    10261 aaatgagaat gattataatt tagaaacact gtatcaattt gtgattgaga aacttttttg
    10321 aagttgcctt gtcatgttat aatgatgcga gtggaaattt gaggaggaaa cacatgagac
    10381 agtggacggc aatccatcta gcgaaattgg cgcgtaaagc aagtagagca gtaggtaaaa
    10441 gaggaacaga tttacctgga caaatcgcta gaaaagtgga tacagatgta ttaagaaaat
    10501 tagcagagca agttgatgat attgtattta tcagtggaac aaatggtaaa acaacgactt
    10561 caaacttaat tggacatact ttaaaagcaa ataatattca aattatacac aataatgaag
    10621 gtgctaatat ggctgcaggt ataacttctg cattcatcat gcaatcaaca cctaagacta
    10681 aaattgcggt aatcgaaatt gatgaaggtt cgattccacg tgtgttaaaa gaagttacac
    10741 cttcaatgat ggtatttact aatttcttta gagatcaaat ggatcgcttc ggtgaaattg
    10801 atattatggt taataacatt gcagagacaa ttagtaataa aggcatcaaa ttattgctaa
    10861 atgctgatga tccatttgtg agtcgtttga aaatcgcaag tgatacgatt gtgtactatg
    10921 gtatgaaagc acatgcccat gaatttgaac aaagtacgat gaatgaaagt agatattgtc
    10981 caaactgtgg tcgcttattg caatacgatt atattcatta taatcaaatt ggtcattatc
    11041 actgtcagtg tggtttcaaa cgagagcaag caaaatatga aatatcaagt tttgatgtgg
    11101 caccgttttt atatttaaat atcaatgatg aaaaatatga tatgaaaatt gcaggtgact
    11161 ttaacgctta taacgcgtta gcagcatata ctgttttaag agagctaggg ttaaatgaac
    11221 aaacaattaa aaatggcttt gaaacgtata catcagacaa tggtcgtatg cagtacttta
    11281 aaaaagaacg aaaagaagcg atgatcaatt tagctaaaaa tcctgcagga atgaatgcaa
    11341 gtttatcagt tggtgaacaa ttagaaggcg aaaaagtgta tgttatttcg ctaaatgata
    11401 acgctgcaga tggtcgagat acttcatgga tttatgatgc agattttgaa aaattatcta
    11461 agcaacaaat tgaagctatc atcgtgacag gtacacgagc agaagaactt caattgcgat
    11521 tgaagttagc agaggttgaa gtaccaatta tagttgagcg tgatatttat aaagcaacgg
    11581 caaagactat ggattataaa ggtttcacag ttgcaatacc aaactataca tcattagcgc
    11641 ctatgcttga acaattaaac cgttcgtttg aaggaggtca atcataatat gcatgaattg
    11701 actatttatc attttatgtc agataaattg aatttataca gtgatatagg aaatattatt
    11761 gctttaagac aacgtgctaa aaaacgaaat attaaagtta atgtcgtaga aatcaatgaa
    11821 acagaaggta ttacctttga tgaatgtgat attttcttta tcggtggtgg aagtgataga
    11881 gaacaagcat tagcaacaaa agaattaagt aaaattaaga caccacttaa agaagcgatt
    11941 gaagatggta tgccgggatt aacaatttgt ggaggctatc aatttttagg aaaaaaatat
    12001 atcacgcctg atggtacaga attagaaggg ttaggtattt tagattttta tactgaatca
    12061 aagacaaacc gattaacagg agatattgtt atcgaaagtg atacttttgg aactattgta
    12121 ggttttgaaa atcacggtgg tagaacatat catgatttcg gtacacttgg tcatgttact
    12181 tttggttatg gtaataatga tgaagataaa aaagaaggca ttcattataa aaatttatta
    12241 ggtacttatt tacacggacc aattttacct aaaaattacg aaatcactga ttatctgtta
    12301 gaaaaagctt gtgaacgtaa ggggattccg tttgagccta aagaaataga taatgaagcg
    12361 gaaatacaag cgaaacaagt attaatagac agagcaaata gacagaagaa atctcgttaa
    12421 ctctgaacat cgcatcaatg gatttaatat tgataaacga tgaagtttag taataaatca
    12481 tatatgtata aacacacaca ttattttgga tggaaacaac caaattgatg tgtgtttttt
    12541 tgttctagtg aataattatt atacaatgag tatctatcct agaattatca atagtaatgg
    12601 tgattatgca acatgaaaaa atgaatgatg aaaggaattt gacgatgaag cccactaaag
    12661 tgattttaag agatgcatct tatttacata gcaaaacatc gataacattt attttaaaag
    12721 atgtagttat cgaagaagat aataaaattt attatttcga cactagtgca actttcgaag
    12781 atcaagaagt taaatttgaa tttgcacttt ttgatagtga catggacaat ttgaaacata
    12841 tggattacga caatcctgtt actgaaatat attttataga acctgattta cattttacaa
    12901 ttattgattt taatcaagaa ctgctttgta tttatattga ttttgattct ggtttaaggc
    12961 attcaaacat ggcaacagaa tctggtattt cattaaggat aaatattgct aaatcagatt
    13021 ttactaaatt tattaatgaa ttagcctctt tatattaatg atttaaatct gatacataat
    13081 tacaatcaaa aaagacagcc acatccctcc gtagtttagg cgtgtggcta tatttgagtc
    13141 tgaatattta tgcttgtaat tttaaaaagg gacatgctat atacgataaa aagaggcggg
    13201 gacataaatc aatgttctat gctctacgaa gttatattgg cagtagttga ctgaacgaaa
    13261 atgcgcttgt aacaagcttt tttcaattct agtcaggggc cccaacaaag agaaattgga
    13321 ttcccaattt ctacagacaa tgcaagttgg ggtgtgggtc ccaacacaga gaatttcgaa
    13381 aagaaattct acaggcaatg cgagttgggg tgggacgacg aaataaattt tacgaaaata
    13441 tcatttctgt cccactccca tggtgccaat tagcataagg tacttaaatt aagcatatct
    13501 gctgtctagc agtcgataaa tcattagaac ttcgtatagt atatgacttt taatttgatt
    13561 ttcaccacta atttcaagtg cttttatagt cgaacgtaaa gtttctacag aatcatcttc
    13621 tctcttaaaa gtaccatcat aaaatatatc tttgatgcta ctactaattt ttagcaatgc
    13681 cattttttcg tcacctgaaa agttaacacg agtattttta ggcaagtaaa tgatatttga
    13741 taaatgagtg ataaacaaac gattcgtata tgcacgttta gttaattgat tgagtaattt
    13801 ccaatcacat tcttttttct tatgatagct taattcatca cgttgataac ttattaacgt
    13861 ttcaacttga ttgtttaaat tgaaaatatt tttatatgct ttttcgcttt tatcagattg
    13921 cagtcttgat aagataagtt cttggcagcg attgtaaaat aatttataca tcaaggcatc
    13981 tgtcttactt aatttttctt cgacctgacc ataatactta ggtggaaaca ccatgaagtt
    14041 aattaaacct gatgtcacga gtccaataat tgctgtcaat gttcgagaca aaaagttgaa
    14101 tatgtaggca tcatgaatac ctggaatcat agctaatgat gttagtacag cgacattcgt
    14161 accaacttgc aatttgagtt ttgtacagaa taaaatcgtg aacgttgcac tcaatgcata
    14221 tgtaaaaggt gattgatcgc cgaataaata tgtaaataat actgcaaagc ctgcaccaat
    14281 taccgtagca ggtaatctac gataaccttt aataagtgat gccttggcag ttggttcaat
    14341 tgtgactaca gctgttaaaa tggcatagat gggtgttaaa tctagtgcca tacaaaagac
    14401 agctgttaaa aaaatggcaa taccagtttt aattgttctg gcaccaatta aatgtttata
    14461 ccattgatcg ttcatttttt aacctctaat catcgtaaaa tcttagcgag cgctttataa
    14521 taatagtatc gtacattgga aaagttcatg tatgtaaaat atttgaaata atcatactta
    14581 agcattactt tgattttcat atacattaat caaagttctg ggctccacaa tgttatattg
    14641 ttagtagttg actgaaataa aatgcacttg taacaagcat ttttcaatta tagtccgggg
    14701 ccccaacaca gaagctgacg aaaagtcagc ttacaataat gtgcaagttg gggtgtgggc
    14761 cccaacacag aagctgacga aaagtcagct tacgataatg tgcaggttgg cggggcccca
    14821 acatagagaa attggatcta caatttctac aggcaatgca agttggggta caacgataaa
    14881 gaaatatttt ttctttatca cactatgtct cactcacttt ccaaaatact aaagtaacat
    14941 ctttagtata tcaaagaatt tttgctataa taagttataa ttatataaaa aaggaacggg
    15001 ataaaatgat tgtaaaaaca gaagaagaat tacaagcgtt aaaagaaatt ggatacatat
    15061 gcgctaaagt gcgcaataca atgcaagctg caaccaaacc aggtatcact acgaaagagc
    15121 ttgataatat tgcgaaagag ttatttgaag aatacggtgc tatttctgcg ccaattcatg
    15181 atgaaaattt tcctggtcaa acgtgtatta gtgtcaatga agaggtggca catgggattc
    15241 caagtaagcg tgtcattcgt gaaggagatt tagtaaatat tgatgtatcg gctttgaaga
    15301 atggctatta tgcagataca ggcatttcat ttgtcgttgg agaatcagat gatccaatga
    15361 aacaaaaagt atgtgacgta gcaacgatgg catttgagaa tgcaattgca aaagtaaaac
    15421 cgggtactaa gttaagtaac attggtaaag cggtgcataa tacagctaga caaaatgatt
    15481 tgaaagtcat taaaaactta acaggtcatg gtgttggttt atcattacat gaagcaccag
    15541 cacatgtact taattacttt gatccaaaag acaaaacatt attaactgaa ggtatggtat
    15601 tagctattga accgtttatc tcatcaaatg catcatttgt tacagaaggt aaaaatgaat
    15661 gggcttttga aacgagcgat aaaagttttg ttgctcaaat tgagcatacg gttatcgtga
    15721 ctaaggatgg tccgatttta acgacaaaaa ttgaagaaga atagttcaac atatactaag
    15781 actaaagtat gaacatcatt tagttccgga gcctattcat attggtttcg gaactgtttt
    15841 ataataatta agaacacaat caatgcgtca tttcaaaaat atgttgtaat aaagtagttt
    15901 ttaagcaaac atatcatcga catcaacgaa gatacatagc gcatttggta ttttaaaact
    15961 tattataaaa ggtgatagtt atgaactatg ttgaacgtta tattgaacag tttttgagag
    16021 caacagtaag aaataatatc aagcactacc ttttaatgct agatgaaaaa atgaaaaatt
    16081 tagatgatta tatgcgttat ttaattacta aaaaagaaca acttagcaag ttaattgaca
    16141 gtctaatgct aacattagaa aataaatata ttgatattgc tgaagcattt caaattcaat
    16201 gtgcaagaga aatcaataat caagaaattg aaaatattaa atcagagttg aataaagttg
    16261 aagcatatta tgcacaaatt gaaactcaaa ttcaacaaac ttcaactgaa aaaatagcaa
    16321 cagaaaaaac atcgtatcta ataaattata tgaacgctgt ggcatagaaa ggcggcgaaa
    16381 catgacacac aaatatatat caacgcaaat gttgatcatt tttactgcat taatgattat
    16441 tgccaatttt tactacatat tttttgaaaa aattggcttt ttactcgttc tattattggg
    16501 atgtgtatta gtttatgtag gatatcttta ttttcataaa atacgtggcc ttttagcgtt
    16561 ttggataggc gcgctattaa ttgcattcac attattgtct aataagtata caatcatcat
    16621 cttgttcgtc tttttattac tacttattgt gcgttattta atacataaat ttaaaccaaa
    16681 aaaagtagtt gcgacggatg aggttatgac ttcaccatct tttattaaac aaaagtggtt
    16741 tggtgagcaa cgtacaccag tttatgtata taagtgggaa gatgtccaaa ttcaacatgg
    16801 aattggcgac ctacatattg acttaacaaa agctgcaaat attaaggaaa ataataccat
    16861 tgttgttaga cacattttag gtaaagtgca ggttatattg ccggttaatt acaatattaa
    16921 tttacatgta gctgcttttt atggaagtac ttacgtgaat gaaaaatcat ataaagttga
    16981 aaataacaat attcatattg aagaaatgat gaaaccggat aactatacag ttaatatcta
    17041 cgtatcaacg tttatcggag acgtagaggt gatttatcga tgaaccacta cattagaaca
    17101 attggttcaa tgctcatctt agtatatagc atgctagctg catttctatt catcgataaa
    17161 gtttttgtaa atatcatcta ttttcaaggt atgttttata cacaaatatt cggaatacca
    17221 gtctttttat ttttaaatct catcatcata ttattgtgta ttattgttgg ttcggtactc
    17281 gcatacaaaa tcaatcagca aaatgattgg attaagacgc aaattgagcg ttcaatggaa
    17341 ggcgaaacag ttggcattaa tgatcaaaat atagaaatat atagtgaaac gttagattta
    17401 taccatacac tcgtaccttt aaatcaagaa ttgcataagt tgcgacttaa aactcaaaac
    17461 ttaaccaatg aaaattataa tattaatgat gtgaaagtta aaaagattat tgaagatgaa
    17521 cgtcaaagac tagctcgaga acttcacgat tctgttagtc agcaactttt tgcggcaagt
    17581 atgatgcttt ctgctatcaa agaaacgaag ttagaaccac cattagacca acaaattccg
    17641 attttagaga aaatggttca agattcgcag ttagaaatgc gtgctttgct gttacattta
    17701 agaccgcttg gtttaaaaga caaatcttta ggtgagggta ttaaagattt agttattgat
    17761 ttacaaaaaa aagtgccaat gaaagttgtg catgaaatac aagattttaa agtgcctaaa
    17821 ggtattgaag atcatttgtt cagaattaca caggaagcaa tttcgaatac attgcgtcat
    17881 tcaaacggta caaaagtgac agtagaattg tttaataaag acgattattt attgttgaga
    17941 attcaagata atggtaaagg ttttaatgtt gatgaaaaat tagaacaaag ttatggactt
    18001 aaaaatatgc gtgaaagagc tttggaaatt ggtgcaacgt tccatattgt atcattgcca
    18061 gattcaggta cacgtatcga ggtgaaagca cctttaaata aggaggattc gtatgacgat
    18121 taaagtattg tttgtggatg atcatgaaat ggtacgtata ggaatttcaa gttatctatc
    18181 aacgcaaagt gatattgaag tagttggtga aggcgcttct ggtaaagaag caattgccaa
    18241 agcccatgag ttgaagccag atttaatttt aatggattta cttatggaag acatggatgg
    18301 tgtagaagcg acgactcaga ttaaaaaaga tttaccgcaa attaaagtat taatgttaac
    18361 tagttttatt gaagataaag aggtatatcg tgcattagat gcaggtgtcg atagttacat
    18421 tttaaaaaca acaagtgcaa aagatatcgc cgatgcagtt cgtaaaactt ctagaggaga
    18481 atctgttttt gaaccggaag ttttagtgaa aatgcgtaac cgtatgaaaa agcgcgcaga
    18541 gttatatgaa atgcttacag aacgagaaat ggaaatatta ttattgattg cgaaaggtta
    18601 ctcaaatcaa gaaattgcta gtgcatcgca tattactatt aaaacggtta agacacatgt
    18661 gagtaacatt ttaagtaagt tagaagtgca agatagaaca caagctgtca tctatgcatt
    18721 ccaacataat ttaattcaat agttcgtatc gaattaagaa aagttactta cgccaatcac
    18781 aatataacat caaatagaca ccaaaaaaca gaggtcttcg caatcattag cgaaaacctc
    18841 tgttttgttg gtgtttagtc ttttttaagc ttatcaacga ttttgtcttt tatattttta
    18901 tcatcttctg gataggtatc actaggatgt tcatcaacat gatacgtacg ttgatgtgtt
    18961 gcattactat cttcatcata ttcgtatcta gtgttctcat tataatgatt tttattattg
    19021 tcatcatgtt ctaatgctgc ttcttcaggt gttttacctt taattacact acgctgatga
    19081 atgattgcat tgatttcagc accgacaatt ataataaaac ttgtgatata taaccatagt
    19141 aataaaatga tgatacccgc gatactgcca tatgttttag aatagttacc aaaatttgaa
    19201 atataccaac caaaaccaaa tgaaccagct aaccaaataa ttgaagtaaa tactgcacct
    19261 ggtaatactg acttaagctt cgttttaacg ttaggtgcaa ccgaatataa cacgataaat
    19321 atgataaata taataatgat tggtaacaca attctaataa ggttaaaaat ccatttcact
    19381 tgttcgtcaa atccaagtgg accgaatagg aaatgactaa ttacagaacc aagcgttggt
    19441 aatgctagag caactacaaa cacaacgccc ataactacag tgaagacaac acttagtagt
    19501 tttaaaacga ttccattacg gctatcttct acatcgtaag caacattgaa agaattcata
    19561 attgcagtca ttccatttga agctgaccaa attgctaaaa tcaaaccgat agataataag
    19621 ccaccactgg agttttgagt tatatcacca attacactct taattagagt agatgtttca
    19681 gcgggtgcat tgcttaacat attagtaatt tgactctgct taatattgaa aaatggtaat
    19741 aatgttaata ggaaaagcaa catagggaac atagcaagta cgaaatggta agtcatttgc
    19801 gctgctagtc ctgaggcatc atcttttcct atgcgataga tgagatatga taagaaatta
    19861 gagtctttct tatattttgc aggtttattt aatcttgata agaagaaaac ctgatcatct
    19921 tttttaggtt tcttagattg gaattgttga ggttcaatat atgtacgatc aacatcaatt
    19981 ttgggattac ttttattttt cttttttgac tcctcttgcg cttccttaac agaattaagg
    20041 tattttgaag aagagtgatc ctttttcgac atgtgcactc cttaaccttt ctctatgtaa
    20101 tgttttataa agtaactatt agtatttatc caattataaa aaaactaaac aatgatatgc
    20161 tttaaaaatg ataatattat agaaattaat tgatttaaat ctttcatagg ctattttgat
    20221 ttaaaattaa aacaaaggca atactgaaac aatgtagttt ggccaatcat tgtattatca
    20281 tttaataatg ataactatga aaggcgtaca ccaaattgtt aagtattgcc ttataaaaac
    20341 aaaatcatct tagcgttgat tttttctatt aacaaatgtt tctttcgcat cctttaatga
    20401 acgttctaat tcaggattat tacgacgaat ttcttcaaca acatctttcc agtataaaac
    20461 ttcgtcttta atcttgctga ctttagaagg cttacgagtg cggttaccat tttttgcatc
    20521 tttaactgat tgaactaaag cttgacgtgt agatttatca gctaaactaa ttgcaccacc
    20581 aattacggca ccaattaaaa taccaggaac aaatttattt tccataaaaa actacccctc
    20641 tttcaaattt gcatctttta cgatgtagtc tattaaatta tcacaagatg ataataccat
    20701 gtcgtataca ccttcaaaat tattcgtgta gtatggatct ggtacatcac tctcttccat
    20761 attactaaat tctaacagtt tgaacaattg tcccttaaga ttaggattga tagatttaat
    20821 attatcaacg ttactttgat ccatagccac aatgtaatca aaatcatctg tcgcttcgaa
    20881 taattcacta atcatgccat caaatggaat attgtgtttg ttgagaattt tttgtgtacc
    20941 ttcatgaggc ggctctccta aattccagct accagtacct cttgaatgta ctttaatatc
    21001 atgaatattt ctgtctttaa gtctttgtcg catgattgct tctgccattg gagaacgaca
    21061 tatattgcca agacagacaa atgctacatc taccattttg attcctccaa actatgtagt
    21121 tatatcccca ttttatagcg actttaaaca ataagaaagc agattatata aaattctatt
    21181 aaagtttatt aaattgtgat actttgataa cataactatt attagaggtg aacattgtgg
    21241 ctatgacaaa tgaagagaaa gtattagcta ttagagagaa gttaaatatt gttaatcaag
    21301 gattattaga tcctgaaaaa tataaaaatg caaatgaaga agaattaaca gatatatatg
    21361 attttgttca atcaagagaa agattgtcgc caagtgaagt gacagctatt gctgacgctt
    21421 taggacaatt gcgacacggc taggagtggg aattttgact aattacaaag aaaagttaca
    21481 acaatacgct gaactattag ttaaggttgg tatgaatgtt caaccaaaac agccagtatt
    21541 tattagatca tcagtagaaa cattagaatt aacgcattta attgtagaag aagcatatca
    21601 ttgtggcgct tcagatgtac gtgttgtata tagcgatcca accttaaaac gcttaaaatt
    21661 tgaaaatgaa tctgtggaac attttgctaa tcatgagata aaatcatatg atgttgaagc
    21721 gagaatggat tacgttaaac gtggcgctgc taatttagca cttattagtg aagatcctga
    21781 tttaatggat ggtatcgata gccaaaaatt acaagcattt caacaacaaa acgcacgcgc
    21841 atttaaagga tatatggaaa gtgtacaaaa aaatcaattt ccatgggtcg tagctgcttt
    21901 tccatctaaa gcttgggcga agagagtata tcctgaacta tctgtagaag aagcatatat
    21961 taagtttatt gacgaggtat ttgatattgt gcgaattgat ggtaacgatc cagttgaaaa
    22021 ttggcgtcaa cacatcgcta atttaagtgt ttacgctcaa aagttacaac aaaaaaatta
    22081 ccatgcgttg cattatgtat ctgaaggtac tgatttaaca gtaggtttag cgaaaaatca
    22141 tatctgggaa gatgctacaa gttatgttaa cggcgaggaa caagctttta ttgctaatat
    22201 accaactgaa gaagtattta cagcaccaga tcgaaataga gtagatggat atgttactaa
    22261 taaattgcct ttaagttata atggaacgat tatcgatcaa tttaaattga tgtttaaaga
    22321 tggagaaatt attgattttt cagctgaaaa aggtgaagcg gtattgaaag atttaatcaa
    22381 taccgatgaa ggttcaagaa gattaggtga agtagcgtta gtacctgatg attcaccgat
    22441 atcaaatcgt aataccattt tttacaatac tttatttgat gaaaatgcag catgtcattt
    22501 agcgattgga tctgcttacg cctttaatat tcaaggtgga acggaaatga ctgttgagga
    22561 aaagattgca agcggattaa atgattcaaa cgtacatgtc gatttcatga ttggtagtag
    22621 tgatttgact atttatggca tattcgaaga tggttcaaaa gaactagtat ttgaaaatgg
    22681 aaattgggca tcaacatttt aataaatgtt attttgaggt gctgagtagg aaatgaaaca
    22741 tgtatttaaa ggtcaaatac gtgattaaag tatagattgg gagataaaat aatgacaaat
    22801 caggacagac caatgaaatc tatgtcagaa tcaaaatgtt ataaaaatag acaagttttc
    22861 cctcaagata cgaatcacca tcatacaatg tttggtggta cattgatggc taatattgat
    22921 gaaattgcag caatcacagc tatgaaacat gctggtgcgc aagtagttac cgcatctaca
    22981 gactcagtag atttcttaaa gccgattaaa acaggggaca tattacaata cgtagcgatg
    23041 gtttcatacg ctgggactag ttcaatggaa gtggtcgttc aaattagaat tgacgatgta
    23101 tttaataaca agcatgattt agctgcatta agttacttaa catttgttgc gttagatgat
    23161 gaaggcaaac ctaaacatgt acctggtgta tatccagaag atgatgttga aaaatggttt
    23221 tatgatacag caccacaacg tgttgaacga agaaaagcac gtcgcattga aagtaaacaa
    23281 acaattgaat atttagctca agtgcaacat attagagact aaaaatataa agacagattg
    23341 ttaaggatga attgaactgt tatgttcgaa tattccacct acaatctgtc tttttgatta
    23401 tgcacgttta tgcttttagt taaaatttaa cctttttatt atagactatt agtcctatta
    23461 aatgaccttt attattaaag tagagtactg ccagcaatta attgtttttt attttataat
    23521 agcattaaaa tatgcggaga ctacttatcg ataaagtgct tctccgcata attaagagtt
    23581 tttaaaattg tataatttgt ggttgtttgt gcatatgacg ctcattatct ttaaaatcca
    23641 tattcggata gtacatattt ttaacaagaa catttggtcc taaacaacta aactcggaac
    23701 aatgacaatt taatgattta gcaagatcag aggataacca tttatcaaat acatctgtta
    23761 atttatcttt ttgtatattc gaaattgtac ctgtttcatc tccgaaatca gttacgatta
    23821 cattacctgt aaatacattg acatttaaac gactacggcc atccgggtca tttctagtcg
    23881 ttacattgtt agcatttctt aaacgtgata gtaacttttg atcttcatca tcctttaagc
    23941 atggaaacac aggcaaagta ccaaataaca tccaaatatc ttcatctctg aaatccaata
    24001 tatcatgaat tgtctttttc atttccgcta gagttaacac atttaattga cttgcaaagt
    24061 cagctggata catagggtga atctcgtgtc tgctacattt catatcatga acgacttctt
    24121 gatgtatttt tcgtaaatgt ggtagcgtac tttgattgag cattgtttcc gcagatacaa
    24181 acattccttg ttctgataat gtacgtgcat tcgaaatcat ttgttcatat aattttaact
    24241 tagcttttaa cggtggttgc ttcttcattg cgccaaagcc aacatttgcg aattcatcag
    24301 ttgttcccca gttatgtgag atatgcataa catcgatata ttcagcaata tctaaataac
    24361 gatcttgagg caatgttagg tttgaattca tttgtgtata tatacctcga tgatgtgcat
    24421 actttaatag aggtttaaca acatttctaa tagacttttt agaaaacatt ggttcgccac
    24481 ctgtaattga catcgttcgc agatttggaa tttcatcaag tctacgataa attaagtcca
    24541 tatctaaagg ctcggggtcg acagtttgta aagtataacc aactgcacag tggctacaac
    24601 gcatattaca aagatttgta gttgtaaatt cgatgttact taaagttaat tggccatgtt
    24661 ctttaacatc gttatatgat tcccatggat cattgtaaat gctaacaggt tgcttcaatt
    24721 tgacgctatt catcgtctta aacttccttc tttctatttg gttcatatcg gtatgatacc
    24781 acttcgtatt atcactcgta acaaattatc tcttaatttt agttaattga aaaggggatt
    24841 tttaaaagtc aaaataattt gaatgtcata aatatagcta agattatatc gctttaacgc
    24901 aatttctgtt aggataataa tgaaaaagaa aacaaaataa aaggagttaa ctttttatga
    24961 atgaacagca aacaatcgaa cagataaaag cacgtttaaa taagtttatt gaggatatcg
    25021 atcatgtaaa tcctgatgaa gtacgtgttg aagatataga tgaatggatt ggattgttag
    25081 atcagcttga agaaaaggtt aaattagtat ctaagtaaat gccacataag atgtgttaga
    25141 gttagatatc gcgatagtcg cttaatattt tttatatctt gtatgtttaa tcactgattt
    25201 acttgtctat agtaattata tcaatgatat atagaaatgt gattttcaat gactaaaaaa
    25261 gtagcaatta ttctagcaaa cgaatttgaa gatatagaat attcaagtcc taaagaggca
    25321 ttagagaatg ctggatttaa tactgtagtg attggggata ctgcaaatag tgaagttgtt
    25381 ggtaaacacg gtgaaaaagt tactgtcgat gtaggcattg cagaagctaa accagaagat
    25441 tatgatgcat tattaattcc tggaggattt tcaccagatc atttacgtgg agatacagaa
    25501 ggtcgatatg gcacatttgc taaatacttt actaaaaatg atgtaccaac atttgccatt
    25561 tgtcatgggc cacaaatact aatagataca gatgatttaa aaggtcgtac gttaacagca
    25621 gtattgaacg tgcgcaaaga tttatcaaat gcaggcgcac atgtagttga tgagtcagta
    25681 gttgtagaca acaatattgt aacaagtcga gtaccagacg atttagatga ttttaatcga
    25741 gaaatcgtta aacaattaca atagaagtat tgtggttatc gattgttaaa atttatatat
    25801 tttcgtttga aatgaaatat ggattttagt tttaataaat gaataacaaa taaaaggtcg
    25861 tctctattgg catttaatag ggatggtctt ttattttaca aaatataaca atatttggca
    25921 tgattaatat ttaaaattgt aatgatttat ctataatctt ttcaaaaaac aaaaaagtaa
    25981 gtatgatggc gtatacgatt gtaagccctt ggactgattt tcccaaaaag tgtagcctat
    26041 ttgtgatagt actggtaaac tcaaggtata tactaagtga gttttaaaag aaggagcaaa
    26101 cgcatgaaaa gaagcgatag gtactcaaac tcaaatgaac attttgagca tatgaaacac
    26161 gaacctcact ataatacgta ttatcaacca gttggcaaac cgccgaaaaa gaaaaaaagt
    26221 aaacgaatac tattaaaaat attattaacc attctaatca ttatcgcatt gtttattggt
    26281 atcatgtatt ttttatctac acgcgataat gtggatgaac taagaaaaat tgaaaataaa
    26341 agtagttttg tgtcagctga taacatgcca gagtatgtta aaggtgcctt tatttcaatg
    26401 gaagatgaac gattctacaa tcatcatgga ttcgatttga aaggtacaac tagagcttta
    26461 ttttcaacga ttagcgacag agatgtgcaa ggtggtagta ccattacaca acaagttgtc
    26521 aaaaattatt tttatgataa tgatcgttca tttactagaa aagtaaaaga attatttgta
    26581 gctcatcgag ttgaaaaaca atataataag aacgaaattt taagctttta tttaaataat
    26641 atttactttg gggataatca atatacgctt gagggcgcag caaaccatta ctttggaaca
    26701 accgtgaata aaaatagtac aacaatgtct cacataacag ttttacaaag cgctatttta
    26761 gctagtaaag tcaatgcacc tagcgtatat aatatcaata atatgtcaga gaattttacg
    26821 caacgtgtaa gcacgaactt agaaaaaatg aagcaacaaa attatatcaa tgaaacacaa
    26881 tatcaacagg ctatgtcaca attaaatcgt taaatacttg cattcatgtg taagatgctt
    26941 ggaactataa tgtagaaggt ttaattgaaa tgtcataatg ataaagttga attgtttctg
    27001 cttaataaat tttacagatt tgcttgtaat cacactttca ttttaaaaga tgatagtgtg
    27061 attttttgtt agcatcgaaa aatatttaaa gttaaacatt tgctatagga agtggcttat
    27121 tgaataataa aagagtattg tataaaactt gagaaagtaa cggggtgatc cagtgccgaa
    27181 gattactaaa atagaagttc aaaagaaaaa caaagaacgt tttaatcttt ttttagacga
    27241 acaatttgaa atgggtatag atatcgatac attagtcaaa tttaatttaa aaaaagggca
    27301 acaacttgaa gctgctgaca tggcagagat tcaaaagtat gatcattatc gcataggttt
    27361 aaacaaagca atccaatatt tatcatataa aaagagaact gaaaaagaag ttattcaata
    27421 tttacaaaaa gaagagatat cagagcaagc gatttctgaa gtgattgaat attgttatcg
    27481 cgaaaagtta atcgaccatc aagattatgc ggaaagttta aaaaatacaa tgattcgcac
    27541 gacagataaa ggacctaaaa tttatcaaca aaaactttat caacttggta tagaaccaaa
    27601 tatcattgaa atgtttacag aactttatag agaacaacag gaacttgatg atattatcca
    27661 aattgctgaa aaaatatcta aaacaaaaaa aggaccacaa aataaggtta aagaaaaagt
    27721 aatgcaatct ttaattcaaa aagggtttga aatggaaacc attcatgctg tattgaatga
    27781 aatggatttt acacaagatg aagcggtttt agacgattta ttacaacgag atttagaaaa
    27841 aatttataat aaaaatcgaa agaagtacac gcaacagaaa ttaatttcaa aaactatcga
    27901 aggccttatg agaaaaggat ataaatatga taaaattaaa gctaaattag aagaaagtgg
    27961 tattgccgat ggaacagaag aaattgagtg agatgtctga gccagaatta agacacgaaa
    28021 tacaacttta taaagagaaa atgagaaaag ctgagatgaa tggtatttta aatgaatatg
    28081 acgtttatca aagtaaagta attgttgccg aaagttactt agtagacaga aaaaagatag
    28141 aaattggtaa aatttataaa ctgactgatg gcagtaatca atattttaaa gtagaaagat
    28201 taaaaggtat ttttgcgtgg gggtttagat ttaatagcga tgaacccgaa gaaggcttac
    28261 ctatagcgtt attacaatta tagaaggatg aaaatagatg ggaagttcaa ttgttttaaa
    28321 gttactaaaa gtaacacact actataggaa taaacagaat aagaaatggt atttaccttt
    28381 tggatatgat gctgaagata tcgatttaaa caatattagt ttacatattt atcaaggaga
    28441 agcattaggt ataattggtg aacctgaatc ttccaaagcg ttggtaggtc aattgttggc
    28501 aggtgcaatt aaacctgata aaggtaaagt agtttgtact gaagatttgt tctacggata
    28561 tattgaagat caatcgttaa ttcatcaaac tgttgaagct tacacagcgc agttagttca
    28621 actatttcca tatgaaatta atgatcataa agctgaacag attattcaat atgcacattt
    28681 aggcgattat aaaacgaagc cggttaacca tatttcgaaa gcggcatacg ctcaattact
    28741 attaagtatt gcacgctcat caaaatcaaa tattattatt ttaaatcatg ttattgacta
    28801 tttaacacca caatttatgg aacgtgcgat tgaattaaca aatgattata ttgaaaataa
    28861 tttaacgatt gtgtcaattg gtgatgatat tgataaaatt tcacaagtga gtaactatat
    28921 agcttggttt tcacatggtc aattaagaat ggaagggtca cttaaacaag ttattccatc
    28981 ttttaaagaa catgaacgtg atcgattaag tttaaactca aaagaagaaa ttgaaaactt
    29041 tgatttagat tggaaaaaga atcgtacaag aataccagag atgacctata atttcaaacg
    29101 cgttgagcgc tataatcatg caaaaccgcc taagttttta gtgcgttttt ggactttagc
    29161 ctcaggtact attttaggct tagcattgat gatgttgctc attttcaata atataggaat
    29221 tatttcgata acagatttta cgaatcgtgc tacgatgcaa aatgaaaata aagatccata
    29281 tggcgaaaag ttagcttatg gaattgcttt taatggcagt gtggatatgc aaggggataa
    29341 acaagtcaca attccaaaat atagtgtagt tacaattact ggcgaaaata gtaaaaatta
    29401 tcgtgttacc gccgataata agacttacta tgttagtaaa gataaattag aatattttaa
    29461 cccggcaggt ttatatcaaa cgcatagttt taaaaaatta gcgccatata tgaaatcaaa
    29521 ttatagtaat tactatgcat actttaacag tcaattacat aaaaagcata gttcagttat
    29581 aaaaacttta gttcctgatg atgataaccg tttcgttgca tccgttacac aacaaccgat
    29641 acaattactt ttcaatgata ataatcagtt atacggtttt gtttatccaa ttgtagataa
    29701 aaaagaatta aaagataagt ttaatattaa caataacatt tggattacta aagttgggaa
    29761 tggatattgt attgccaatt tgaaagaaga caaatggatt tatattgaat tgtaggtgta
    29821 aagatgctag ataatattat tttatatttt aaaaacttac cgcatactaa aaggtatgta
    29881 acagaacgtt taaaacaaag ttggaaaagt tttctaatcg tattagctgc atgtttaata
    29941 cttattattg caagtgaaac gctattttcc tttagtcatt tgaccgatgt taaagaggtg
    30001 cgatggttat ttagaattat tgcattgatt gtttttgcgg tattgatgtt cacaatttat
    30061 atctcttatc atcattatat gaatgacttt ttagtgacta agttatttaa tatttccgca
    30121 gcgacgccag tagttattat gtctatttta agttttatta tgctagtcat tttgacgatg
    30181 attagtgcat tggttaaacc agtaaacttc gaaacatcat atatagcgct attctatttt
    30241 attgtgatgg caactatttt tgtaggatta atatccgtta cttttggtct tattcgactg
    30301 ttaactgaaa aaataaatat catattttat ggggtttgtg tattgtgtat cttattgtta
    30361 ccaattattt tcataccaaa tccaaatcat gtatttatca atcacatcct aatgctgaat
    30421 ccaatgtatt acattgttaa tggtatagca caatctatca tatttggtat atcaagtatg
    30481 gaaaacattc catatcattt ttactttatt ttattcttat gtttaatagc tgcagtaaat
    30541 ttcgtattag caaggtatac gacacacgca atttataata aaacatctaa agtgacacaa
    30601 actgataatc aacaagatgt ttcaaatgat agtacagacg aggcggatac ttcttcatga
    30661 tgtttagctg acctgttgtg taaattaatc tgtgagaatc agaaacaatt agaatatcat
    30721 ctagatattg ttttcctata ctgattttga tatttcgagt cattaaaggt agtttgttag
    30781 caacaatata aattttagat tttgtaaaag cattcatagt tttacattaa aaaaccggac
    30841 agagtaaaaa tcgttttgat tttcattctg cccggttgtt cattttttat agattaactt
    30901 tagtgaataa taacttgaaa ttatttagca tacagtttac gttgtaactt atcttctgta
    30961 aatacccagc caatataaga gtggtctatg acattatcgt ttgttacatg tgcaattgcc
    31021 acaaatgaat aatgatcatt ttttaaataa cgcaaatcaa tcaaacgaat ttcagtagaa
    31081 ccatctgcta acgttgttgt ttgccaacga tagattgatg aaaagtttaa aaaagtacgt
    31141 atatctttat tacctttgac tttccataaa atggagtctg ttgataatgt ttgacgttcc
    31201 actttatcac taaacaccac attcctacca tatgcttttc caacatagtc atgtgcatca
    31261 gtttgtatcg cgacacgcca ttccataaat tttattgttg gcgcaacaaa tactttaaca
    31321 gggtgatgct cttgttgaat tgcttttaaa gcttgttgct taattacggc tctcatttta
    31381 aaacgaatca tgtaataaat gattagtaaa gcgattatag gaaagaagac tgcaaatgga
    31441 tgcaagccta taacccataa tacaatacca atacaaagaa ctgtgaaaat aatagggtca
    31501 aatgtgttaa tcacacttaa ttgaatccat ttgtttgtga taggtctaag cgcttgtgta
    31561 ccataagaat tgaatatatc tacaaagaca tgtaaaaata ctgcgagctg agcccacatc
    31621 catacatgaa atgggttggt tccactaaag aacgtgaata ttaaaaatgt aattaaaatt
    31681 ggccatagta ttgtgaaagg gatggaatgc gtgatacctc tatgatgcga aatatatgtt
    31741 gcattgtcct ttaatttaag aacagtatcc ccatcaggaa ttaatgaacc aacgataagg
    31801 gttgtagctg ttgcaccaaa cgtagaagcc attgctggat cttgagttgc aagtgctgta
    31861 aggcccaccc caattgcgat atgtgttgca gtgtccatat cagttcactc atttcataat
    31921 attatatata ctattataat ccaatttcgc aaataactaa attaacttac atactaacca
    31981 tgattttaat gtacaataaa aacattatga gtaaagacaa ttaattttgg tgaggaaagg
    32041 gttttataaa tgtatcagca gtctagtttt aaagaaaatt tgatacactg gtttgatgaa
    32101 aatcaaagag aaatgccatg gcgacaaacg accaatccgt actatatttg gttaagtgag
    32161 gtcatgttac aacagacaca agttaaaaca gttattgact attatcttcg ttttgttgaa
    32221 cgatttccaa ctgtggaagt tttgagtcaa gcttcggaag atgaagtgtt aaagtattgg
    32281 gaaggcttag gatattatag tagagctcga aattttcata cggcgattaa agaagtttat
    32341 gataaatatg aaggcttagt tcccaaagat cctgatcaat ttaaagcgtt aaaaggtgtt
    32401 ggcccataca cacaagctgc agtaatgagc attgcatata atgtaccact agcaactgta
    32461 gacggaaatg tttttcgagt atggtctaga ttgaatgatg actatcgaga tattaaatta
    32521 caatcgacga ggaaatcgta cgaacaagaa ttgttaccgt atgttactac agaagctgga
    32581 acgtttaatc aagctatgat ggaattaggg gcattaattt gtacaccaaa aaatccatta
    32641 tgcttatttt gtccagttca agaaaactgt gaggcatttg ataaaggtac atttgaaaag
    32701 ttacctgtta aatctaaaaa tgtaagtaaa aaagtaattg agcaatccgt ctttttaatt
    32761 agaaataatc aaggtcaata tctgttgcaa aagcgtagcg aaaaattatt gcatggtatg
    32821 tggcaatttc ctatgtttga aagtgagcat gctagacgta aaatgactga aaaaatcggt
    32881 catgacattc aaccagtaga aacacctatt tttgagttga agcatcaatt tactcattta
    32941 acatggaaga ttaaagtata cgccgcttca ggagcaatta acattgaaac attaccagat
    33001 gacatgattt ggtttaattt aagtgatcga gaccaatata cattccctgt acctatgtca
    33061 aagatttatc aatttataaa tgggtaacat tcgatgattg gtaatattat cggaaaacat
    33121 agtgacatta attttaaaaa tgtataaatg atatctttaa atctcatagg ataacaatgt
    33181 caaaaagtta aagtgttgat ttataaaagt gatgatttta catactttaa atgggacatg
    33241 taaatctctg ttgtagtact tagcaatatt accgagttta atcattaagt agtaaaatct
    33301 tatttcgtaa aaatatgtat ttatataata ctatttctga aatatgctat aatttataat
    33361 ggttaaatta acagaaggtg gtgtggagta tggtcagaga atccatacct aaagaagggg
    33421 aaaacattaa aattcagagt tataaacatg atggtaagat tcatcgcgtt tggtctgaaa
    33481 caacaatatt aaagggtact gatcatgttg tcattggtgg caatgatcat acgttagtga
    33541 ctgaaagtga cggaagaact tggataacac gtgaaccggc aattgtttac tttcactcag
    33601 aatattggtt taatgttatc tgcatgttta gagaagatgg aatttattac tattgcaatt
    33661 tgtcatcacc atttgtttgt gatgaagagg cattaaaata tatagactat gatttagata
    33721 ttaaagtata tccaaacgga aagtatcatt tattagatga agatgaatat gagcaacata
    33781 tgaatcaaat gaattatccg catgatattg atattatttt aagacgcaac gtggacattc
    33841 ttcaacaatg gatagaacag aagaagggcc cattcgcgcc agattttatc aaagtttgga
    33901 aagaacgtta caaaaaaatt agacagtatt aagcaaataa agtgtaaata ctgattaaat
    33961 catttatatt gacttagtga tgtaaagaag tatgataact tttgctgtcg tgtggggaca
    34021 cagtatccat agattaaatt gaatagaata taacatacga ataagacaac gtatttaatc
    34081 acatgaatat gacagaggtt gagatatctt aattttaaaa atgtaaattg taagaagaat
    34141 ttacatctac aaattatgta tccaacctct attcattttt atgcttatga ataggatagg
    34201 gcaatagatt aggggggatt gtatgattaa acgatatttg caatttgtta agccatataa
    34261 atatcgtatt tttgcaacga ttattgttgg gataattaag tttggtatac caatgcttat
    34321 accactttta attaaatatg caatagatgg cgtggttaat aaccacgcac taacgactga
    34381 tgaaaaagtt catcatttaa ctattgccat tggtatcgca ttatttattt ttgtaatagt
    34441 gagaccacca attgaattta tacgtcaata tttggcgcaa tggacaagta ataaaatatt
    34501 gtatgatata cgtaaaaagt tatataacca tttacaagct ttaagtgcga gattttatgc
    34561 taataatcaa gtaggtcaag taatatctag agtgattaat gatgttgaac aaacaaaaga
    34621 tttcatttta accgggttaa tgaatatttg gttagattgt ataacaatta ttattgcact
    34681 atccataatg ttctttttag atgtgaaatt gactttagca gcactgttta tcttcccatt
    34741 ttacatttta acggtgtacg ttttctttgg aagattaaga aaattgacgc gtgagagatc
    34801 gcaagcatta gctgaggttc aaggattctt gcatgaacgt gttcaaggta tttcagtcgt
    34861 taaaagtttt gcgattgaag acaatgaagc gaaaaacttt gataaaaaga atactaattt
    34921 cttaacacgt gcgttgaaac atacaagatg gaatgcctat tcctttgccg caattaatac
    34981 agttacagat attggaccaa ttattgtcat cggtgttggt gcatatcttg ctatttctgg
    35041 atcaatcaca gtaggtacac ttgcagcatt tgttggatac ttagagttat tgttcgggcc
    35101 tttacgtcgt ttagtcgcat catttacaac tttaacgcaa agttttgctt caatggaccg
    35161 tgtattccaa ttaattgacg aagattatga cattaaaaat ggtgttggtg ctcaacctat
    35221 tgaaattaaa caaggtcgta ttgatattga tcatgttagt tttcaatata acgataacga
    35281 agctccaatt ttaaaagata ttaatttgag tattgaaaaa ggagaaacag ttgctttcgt
    35341 aggtatgagt ggtggtggta aatcaacatt aattaactta ataccgagat tttacgatgt
    35401 aacttctggg caaattttaa tagatggtca caatattaaa gattttttaa cgggaagttt
    35461 aagaaatcaa ataggattgg tgcaacagga taatatttta ttctctgata cagttaagga
    35521 aaatatttta cttggtcgtc caacagcaac agatgaagaa gtagttgaag cggcgaaaat
    35581 ggctaatgca catgacttta ttatgaactt gccacaggga tatgacactg aagtaggtga
    35641 acgaggtgtt aaattatcag gtggtcaaaa acaaagatta tcgattgcta gaatattttt
    35701 aaataatccg ccaattctta tcttggatga agcaacaagt gcacttgatt taaaaaatga
    35761 atccattatt caagaagcat tagatgtgtt gagtaaagat cgaacgacac ttatcgtagc
    35821 gcatcgcttg tccactatta cacatgctga caaaattgtc gtaattgaaa atggacatat
    35881 tgttgaaaca ggtacgcatc gtgaattgat tgcaaaacaa ggtgcttacg agcatttata
    35941 tagcattcaa aacttataaa gtattagttg tttgacttca gtacaatctt gtagggaaga
    36001 tttgtaacag gatggtgggg tcataacata gaaaagcagt aagagatttt cttcattgaa
    36061 aataatctta ctgctttttt aaatttaatt tcgagattca atattacttt atctcattgt
    36121 ggtattaatt acaggaattg ctttaaactt ataaatcaaa gtcttcttca acaatttcaa
    36181 tgtctgcatc agacctatga tatgtgaaaa agctaattct tatgcggtct aaatgctcta
    36241 aatggtgtcg atactcttcg atggctgcaa caatttgcat aacattggca aacgaatatt
    36301 ccgtttgata aggatgattt attaactcat gctgaaatgt agacaataaa tcttttttct
    36361 gcggattatc taactcataa tcaacatgtg tcacattata acgtgctttt ttagaaaggc
    36421 tagctaaaat ttgctcgtga aaagcagtta atgaatctaa atctaatttg atttgtaata
    36481 ggaaattgtt attaagtaaa tataagtcgt tttgataacg cgacaatttg tttaatactt
    36541 cataagcttg tctagtcgtc tgaactactt ctctgaaaag tattttcttt ctattctgtt
    36601 ggtgaatatg tttttttgta ataggacgtt cttcgctata gtaatcataa attttctcta
    36661 acttttcgac acgttgtttt aaattatgac tatcttgttt aatattatta aactccgtcg
    36721 tatcatttaa tactaattta aaccacataa aaatatctga ggatatattt aatgaattat
    36781 agtaaatttt tgtttcaaat ttaggtggta gaaacacaaa gttaactaga gatgaactta
    36841 tgacaccaat cattacaagt acaaacctgt aaaaggcggt aatatagaaa gaaccggtat
    36901 gttgtcccat aatgattaat gctgttacac tcgccaaagt agcaacatgt gctaaattaa
    36961 atttaaataa aatagcaata agtactatga cggtaacacc cataatgata aaattatcac
    37021 taaaaattgt taccattgta acagataata tggcacctat aatgttaccc aatgcttgat
    37081 cagaaactgt tttaaatgaa cgataaatac taggttgcat tgcaacaaca gcactgacac
    37141 cagctaaggc tttcagacca acatcatccg gtagtaaaga agcgatagac atagctaaaa
    37201 taatggctat accagtttta aaaatccgag ctcctagtct caaaaataat gacgcccctt
    37261 ttaagtttat tgaatatcta atattcgtat tcattactgt tatacactta ctagttataa
    37321 aattcaagct tatttatagt tgttaaaata aatcatacat aatactgata gcgatgtaaa
    37381 actttagtca gagattaaaa gagtataaat ttgtaaaata aaaactcaca tagtgacata
    37441 tcaagttaaa cgttaatagt taacgatata aaatgaatct actatgtgag catttgtttt
    37501 attttaattc aattaaaaat atacttcctt aaaagttatt tcatttgact aaaagcatag
    37561 tctgcagctt ttaaagtttg ttgaatatct tcttctgtat gttcagttgt taagaaccaa
    37621 gcttcaaact tagaaggtgc taaattgata ccttgattta acattaattt gaaaaattta
    37681 ccgaacgctt cgccgtcaga atgttcaact tgatcataat gtgtgacttt ttcatctgta
    37741 aagtacaatg ttaaagatcc ataaatacga ttaattgtag ctgtgatatt atgtttttcg
    37801 attaatttaa gtaaaccttc ttctagttgt tggcctaagc tgtctaattt ttcataaaca
    37861 ccgtcttgtt ctagtacttc gagtaatgca atacctgctt tcatagataa cgggttacca
    37921 gccattgtac cagcttgata tgcaggtcct agaggtgcta cttgttccat aatatcttga
    37981 cgtccaccat agcctccaat tggtaaacca ccgccaacaa ttttaccaaa tgcagttaaa
    38041 tcagggataa cacctaataa atcttgagcg gcaccgtaat ggaaacggaa tgcagtaatt
    38101 acttcatcat aaatcactag tgtcccattg ttatgcgaaa tttcattaac ctcttctaaa
    38161 aatccaggtt gaggcattac cattccaaag ttaccaacaa ttggttctac taatactgcg
    38221 gcaatttcat caccccaaaa ttcaattgct tctttatatg cgttaatatc attgaaaggt
    38281 acagtaatga cttcacgtgc gacgctttct ggaacaccag ctgagtctgg agaaccgagc
    38341 tgagatgggc cactacctgc tgcaaccaat actaaatcag aatggccatg ataagatcca
    38401 gcaaatttta taattttatt tcttttagta tatgcacgtg caacacgaat tgttgtcatg
    38461 actgcttctg ttccagaatt tacaaagcga attttctcaa gagatggaat tgcatcacgt
    38521 aattttttgc tgaattcaat ttctagttca gtcggtgtac caaataaaac acctttggct
    38581 gcttgttctt gaattgcttt agtaatatga ggatgtgcat gccccgcaat aattggaccg
    38641 tatgcttgaa ggtaatcaat aaatttattg ccatcgacat catataaata tgcaccgtgt
    38701 ccttctttca taacaacagg tgcaccgcct cctacagctt tataagaacg agaaggggaa
    38761 ttgacaccgc ctagaatata ttcgtttgaa agttgttgta aacgttcact ttcactaaaa
    38821 ttcatttata tcaacctctt ttaatttaat attttcatct aatatcgtat cataaaatta
    38881 ttataatgaa gaaaaaggtg attatatgtt gcaaaaagga gaacaatttc caatatttaa
    38941 attagaaaat caagacggaa ctgtcattac aaatgataca ttaaaaggta aaaaggcgat
    39001 tatatatttt tatcctagag ataatacacc tacttgtacc acagaagctt gtgactttag
    39061 agacaattta gaaatgttca atgatttaga tgttgcagta tatggtataa gcggtgattc
    39121 aaagaaaaaa caccaaaatt ttattgagaa acacggattg aatttcgatt tattagtaga
    39181 tgaagatttt aaattagcta aagaaacagg cgtatatcag ttaaaaaaat catttggcaa
    39241 agaaagtatg ggtattgtaa gaacaacttt tataatagat gaacaaggta aagtattaga
    39301 tgttatcgag aaggttaagg ttaaaacaca aatagaagaa cttaaaaaca ttttggggtg
    39361 acatatatga aagttgttgg gttaaatcgt atgcgtgaag ttgaaactga attacaacaa
    39421 cgcttttcag atttagattt taaattttat aaaaaagcat cagaaatacc tgagagtgac
    39481 ttggctgatt tagatatatt agttggttat gatggcggta tcaatgaggc atttttacaa
    39541 cgttgcccga atttaaaatg gattgcatgg tttgcaacgg gtgtaaatac attaccgtta
    39601 gattatattg cagatcacgg catactttta actaatggaa aaggtgttca agctaaacaa
    39661 ttatctgaat acattttagc tttcatttta gatgattata aaaagatgaa actatcatat
    39721 gataaccaaa gacaacatat atatgattcg aaaataactg gtaaacgcct atcaggacaa
    39781 acagttttat ttttaggtac aggtgcaatt gctactagaa ctgcgaagtt agcaaaggct
    39841 tttaatatga atttaattgg tctgagcaag tcaggtcaga acaaagatga gtttgacgag
    39901 atatatacta tcgaatcact tgaaagcaca ttaccaaatg ctgacattat tataaatgct
    39961 ttaccagaaa cgcaagaaac gattcattta ctaaagaaaa aacattttga attaatgaaa
    40021 gatgaagcac tttttataaa tataggacga ggtagcatag ttaaagaagc gctcttaata
    40081 gaagtattaa aaagtaaagt tattcgacat gcatatttag atgtgtttga aaatgaacct
    40141 ttgaaaccta atcatgaatt atatgaattg gaaaatgtaa ctataacagc gcatataact
    40201 ggtaatgatt atgaggcaaa gtatgactta ttagatattt ttaaaaacaa tctagttaat
    40261 tttctcaata agaatggtct aattgagaat gaagttgatg ctaaaaaagg ctattaaatg
    40321 aaatcatcat gtaaatattg acacgcgcgc aatactacag ttatatttat agtaagtaat
    40381 aataattatt atataagaaa gatggtgata tagatgagtg ttgaaataga atcaattgaa
    40441 catgaactag aagaatcaat tgcatcattg cgacaagcag gcataagaat tacacctcaa
    40501 agacaagcaa tattacgtta tttaatttct tcacatactc atccaacagc tgatgaaatt
    40561 tatcaagcac tttcacctga ttttccaaat ataagtgttg cgacaatata taataactta
    40621 agagtgttta aagatattgg aattgtaaaa gaattaacat atggagactc atcaagtcga
    40681 ttcgacttta atacacataa tcattatcat attatatgtg aacaatgtgg taagattgtt
    40741 gattttcaat atccacagtt aaatgaaatt gaaagattag ctcagcatat gactgacttt
    40801 gacgtaacac atcatcgaat ggaaatttat ggagtttgta aagaatgcca agataaataa
    40861 tttaactttg gtagtatgac aaattaaaaa agcgttagct tacttcatat aagtaagtgt
    40921 aatatttaag aagttaaacg acatgaaagt tgtttaactt cttttttatg cttattctga
    40981 aaaatattta aattgaagaa aagaatattc taactacgga agtggtatta actaataact
    41041 agtacccttt ataaataaac ataaaaatat tcaaacgaag gtctactaaa taactatcca
    41101 taaagtgagt ataagtttgt ttgtaaaact gaagtaaaaa gcgtaaggaa ttacacttta
    41161 aatacatata gtacttacga atagaaaata atcccttcaa cagtaatttt taaacaaaaa
    41221 taagtgttgt tttatgttga ctctactaga ataacttgat attatataaa agtcgtcaaa
    41281 cggcactaat atttaaaaaa caaatgtttt aagttgttga tttaaaatat taataaagtg
    41341 taaatttgac tattgaaatt cgaacaaata cataataaaa taatatttgt tgaattaatt
    41401 gagttaggaa atttattttt tagaaataaa ataattaaaa ataattcttg acttacaaaa
    41461 acttacgagt tataattaaa tgttgtaagt gacaaa
//
LOCUS       DAPDIM010000018        41309 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000018 DAPDIM010000000
VERSION     DAPDIM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 41309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41309
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.018"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..846
                     /locus_tag="RFE25_001028"
     CDS             <1..846
                     /locus_tag="RFE25_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDU2816116.1"
                     /translation="PMLSLFFFYSAFAVPFTFKNNVKKTATNLFILTMIICTIITYLL
                     YNNYFVAMMVYYVVISLIMLDNFKKMKNREYQKEIAEKNRHINTLIAEQERHRIGQDL
                     HDTLGHVFASLSLKSELAYKLIDTDVEKVKAELLAINKLSRESLNKVREIIDDVKLPS
                     FIEEIDSIRKVLKDADIDFTFENKELAQVLSPTKQSMLVMITREAINNVIKHANASKV
                     HGKLKTVNNHKLLLMIEDDGKGIDSDCEVKSISQRVQHLNGTLAVDSTNGTKIIIEIS
                     TGGIA"
     gene            843..1445
                     /locus_tag="RFE25_001029"
     CDS             843..1445
                     /locus_tag="RFE25_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2816117.1"
                     /translation="MTSLIIAEDQNMLRQAMVQLIKLHGDFEILADTDNGLDAMKLIE
                     EYNPNVVILDIEMPGMTGLEVLAEIRKKHLNIKVIIVTTFKRPGYFEKAVVNDVDAYV
                     LKERSIEELVETINKVNNGEKEYSATLMTSFFVDKNPLTPKEQIVLREIGNGLSSKEI
                     SEKLFLTDGTVRNYTSVIIDKLFADNRFDAWKKANEKGWI"
     gene            complement(1558..1746)
                     /locus_tag="RFE25_001030"
     CDS             complement(1558..1746)
                     /locus_tag="RFE25_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LapA family protein"
                     /protein_id="HDU2816118.1"
                     /translation="MNISNENTVTLIAVIIAIIIGIFLQIFFKLPLIVTAVLSILLGI
                     FVGFIVYLIVSFYNKRKN"
     gene            1885..2418
                     /locus_tag="RFE25_001031"
     CDS             1885..2418
                     /locus_tag="RFE25_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDU2816119.1"
                     /translation="MKSNKSLAMIVVAIIIVGVLAFQFMNHTGPFKKGTNHETVQDLN
                     GKDKVHVQRVVDGDTFIANQNGKEIKVRLIGVDTPETVKPNTPVQPFGKEASNYSKKT
                     LTNQDVYLEYDKEKQDRYGRTLAYVWISKDRMYNKELVEKGLAREKYFSPNGKYRNVF
                     IEAQNKAKQQKLNIWSK"
     gene            complement(2563..3417)
                     /locus_tag="RFE25_001032"
     CDS             complement(2563..3417)
                     /locus_tag="RFE25_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816120.1"
                     /translation="MSFYVVLIIIIVALIGILVLNQRYSNSKIDTEVYARKQLIKKNK
                     ALSAENAELRSQMLSSNNDVGHHAYKNAKRELRKILDSYLENGKLKYYDIIVTSNLAT
                     KHPFFEYARSFDFIIVSDIGLINVDVKSWGEKTFYHFDVPDEHDTEMSNSNIEKVVGH
                     YISQQYHDQFNSSRKSIYTFTETVQPNRVIYDFYDYDPYQLAANNAKALKDHIEQNFN
                     FKVQSTGVIYFSDGTVNIIQGSEERDKYVDTVSTKSSLRRIISEAIELSKHPLNKEQV
                     DQITAIFK"
     gene            3748..4323
                     /locus_tag="RFE25_001033"
     CDS             3748..4323
                     /locus_tag="RFE25_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816121.1"
                     /translation="MNAKEQLVDNLMKTSSQLFKFHGEVAMQLFLNDELKLPSIVEIC
                     VERKRLSDIVKVIPQSYALLYIDKQDQAIAKEDLSLSKIAKVYVQYDDTTIMSIFVYD
                     VVNDEWIFRLDPNIRIPKSNIYFHSLNWDVDYIKPEIVLMYDLMQHHQYHHYSNYKRV
                     IDALSYYQFFILKFVVGEQRIKDAIQRTINN"
     gene            complement(4377..5759)
                     /locus_tag="RFE25_001034"
     CDS             complement(4377..5759)
                     /locus_tag="RFE25_001034"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDU2816122.1"
                     /translation="MKVSKFGGSSVSNATQIKKVLNIVNSDPERKIVIVSAPGKRHDN
                     DIKTTDLLIRLYEKVINHLDYHDKKREIIQRYDDIVKELQMDESILRTIDVTLEHYIN
                     QLKNEPKRLLDALLSCGEDFNAQLIALYNNSQGIPTKYISPKEAGIFVTDVPQEAQIL
                     DSAYSEIKKLRDYDEKLIIPGFFGVSHEGYIVTFPRGGSDITGAIISSGVRATIYENF
                     TDVSGIYKANPNIIKDPELIEEITYREMRELSYAGFSVFHDEALQPLYKDRIPVVIKN
                     TNRPQDKGTFIVHDREINAKNVISGISCDKDFTVINIKKYLMNRQVGFTRKILGVLED
                     NNISFDHMPSGIDTISIVMRSKQIQNKETKVLNEIRQKCDVDELSIEHDLAILMIVGE
                     GMNKVIGTANKITHALAESKINLKMINQGASEISMMFGIHVDDAEKAVLSTYEFCYHG
                     VALKNLCDKN"
     gene            5950..7230
                     /locus_tag="RFE25_001035"
     CDS             5950..7230
                     /locus_tag="RFE25_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDU2816123.1"
                     /translation="MKKLNIALLGLGTVGSGVVKIIEENRQQIQDTLNKDIVIKHILV
                     RDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVMGGIEPTVDWLRTALKNKKHVIT
                     ANKDLLAVHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG
                     TSNFILSKMTKEQTTFEEALDEAKRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVI
                     KLNDVKRRGISGVTLTDINVADQLGYKIKLIGKGIYENGKVNASVEPTLIDKKHQLAA
                     VEDEYNAIYVIGDAVGDTMFYGKGAGSLATGSAVVSDLLNVALFFESDLHTLPPHFEL
                     KTDKTREMMDSDAEINIKEKSNFFVVVNHVKGSIENFENELKAILPFHRSLRVANYDN
                     QSYAAVIVGLESSPEELITKHGYEVDKVYPVEGV"
     gene            7236..8297
                     /locus_tag="RFE25_001036"
     CDS             7236..8297
                     /locus_tag="RFE25_001036"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDU2816124.1"
                     /translation="MRRWQGLVEEFKAHLPVNENTPKLTLNEGNTPLIHCENMSKILG
                     IDLYVKYEGANPTGSFKDRGMVMAVTKAKEQGKKIVICASTGNTSASAAAYAARAGLK
                     AIVVIPEGKIALGKLSQAVMYGAEIVSIEGNFDEALEIVKEIAKSGEIELVNSVNPFR
                     IEGQKTGSFEIVQQLDGEAPDILAIPVGNAGNITAYWKGFKEYHEAKGSQLPKMFGFQ
                     AEGASPIVQNKVIKNPETIATAIRIGNPASWDKATNALKESNGLIDSVTDDEILEAYQ
                     LMTTKEGVFSEPASNASIAGLIKLHRQGKLPQGKKVVAILTGNGLKDPDTAISLLDNP
                     IKPLQNDKDSIIDYIKGAL"
     gene            8299..9213
                     /locus_tag="RFE25_001037"
     CDS             8299..9213
                     /locus_tag="RFE25_001037"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDU2816125.1"
                     /translation="MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWE
                     YIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPILCIEMRSDIPLARGLGSSASAL
                     VGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGFYNDVSKETSVAH
                     IDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAG
                     KLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVR
                     SLNSQVVSCHSELVDINISGVKERIVYQ"
     gene            9271..10074
                     /locus_tag="RFE25_001038"
     CDS             9271..10074
                     /locus_tag="RFE25_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDU2816126.1"
                     /translation="MTNYKVVVLDMDDTLLNSDNVISEETANYLTAIQDEGYYVVLAS
                     GRPTEGMIPTARDLKLPEHHSYIISYNGSKTINMTNEEVEVSKSIGKQDFDEIVDYCR
                     DRGFFVLTYHDGQIIYDSEHEYMNIEAELTGLPMKRVDDIKAYIQGDVPKVMGVDYVA
                     NITEARIDLNGVFNDNVDATTSKPFFLEFMAKDVSKGNAIKALCHKLGYSVDQVIAFG
                     DSMNDKSMFEVAGLAIAMGNASDELKQYADEVTLDHNENGIPHALKKLL"
     gene            complement(10367..10681)
                     /locus_tag="RFE25_001039"
     CDS             complement(10367..10681)
                     /locus_tag="RFE25_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816127.1"
                     /translation="MIGQTNLFDDVLKQDERFVIVVQALEEKNGQLLKRTLREYPGLN
                     HKQMNDLFTHLKELFSEESFAENQSAFSITVYTNLDYTADQIYAHVKRFRGKHDWTQT
                     AK"
     gene            complement(10656..10760)
                     /locus_tag="RFE25_001040"
     CDS             complement(10656..10760)
                     /locus_tag="RFE25_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816128.1"
                     /translation="MLPFFILEILHIVYNIDNNNFSGVKFNDWTNKFI"
     gene            complement(10899..12353)
                     /locus_tag="RFE25_001041"
     CDS             complement(10899..12353)
                     /locus_tag="RFE25_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDU2816129.1"
                     /translation="MEDNKMNRSLNSRHISMIAIGGAIGTGLFVATGNIISQAGPGGA
                     ILAYLVIGVMLYFLMSSIGELATFYPVSGSFSSYSTRFIDSSLGFTMGWLYWALWSLV
                     TSVDVIVASNVLYFWDTFKFFHPITWSLIFITILLLLNIFSVKSFGETEFWLSLIKVL
                     TIIVFVIFGFLMIFGILGGHTYGFENYTKGQAPFVGGISGFLGVLLVAGFSVGGTEVV
                     AVTAGESDDPKKSMPKAIKQVFWRILLFYVLSIAVIGVIIPYTDPSLLRASSSISQSP
                     FTIVFDRVGIAFAASVINAVILTSLLSAANSGVYTTGRMLYSLSSDKKAPQFLSKLNK
                     TTKLPLRALLTTYAVVVIVIIYANFNSNAVFNLLEIIGSMIIVVWGSSIWSQIRLRQA
                     IKKQGQDPNKVLPYKAPFYPLGPIIVITTLLFLLFGGSVEYILKDQWLNAFKNFLPLI
                     ILALIYFIHKIIHKTKFVKLETINLKPHDYDNQK"
     gene            12557..14074
                     /locus_tag="RFE25_001042"
     CDS             12557..14074
                     /locus_tag="RFE25_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase"
                     /protein_id="HDU2816130.1"
                     /translation="MSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQ
                     FDREVIPERRMHAKGSGAFGTFTVTKDITKYTNAKIFSEIGKQTEMFARFSTVAGERG
                     AADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRDA
                     QNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFR
                     TQQGIENLTDEEAAEIIATDRDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDN
                     PFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPTNIIPGLDFSPDKMLQG
                     RLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPN
                     NHGKFDSQPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTA
                     NAMEGVTDDVKRRHIRHCYKADPEYGKGVAKALGIDINSIDLETENDETYENFEK"
     gene            14165..14314
                     /gene="rpmG"
                     /locus_tag="RFE25_001043"
     CDS             14165..14314
                     /gene="rpmG"
                     /locus_tag="RFE25_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDU2816131.1"
                     /translation="MRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTL
                     HRETK"
     gene            14768..15037
                     /gene="rpsN"
                     /locus_tag="RFE25_001044"
     CDS             14768..15037
                     /gene="rpsN"
                     /locus_tag="RFE25_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDU2816132.1"
                     /translation="MAKKSKIAKERKREELVNKYYELRKELKAKGDYEALRKLPRDSS
                     PTRLTRRCKVTGRPRGVLRKFEMSRIAFREHAHKGQIPGVKKSSW"
     gene            15194..16171
                     /gene="guaC"
                     /locus_tag="RFE25_001045"
     CDS             15194..16171
                     /gene="guaC"
                     /locus_tag="RFE25_001045"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDU2816133.1"
                     /translation="MKIFDYEDIQLIPNKCIVESRSECDTTIQFGPKKFKLPVVPANM
                     QTVMNEKLAKWFAENDYFYIMHRFDEEARIPFIKHMQNSGLFASISVGVKKAEFDFIE
                     KLAQEKLIPEYITIDIAHGHSDSVINMIKHIKNHIPDSFVIAGNVGTPEGVRELENAG
                     ADATKVGIGPGRVCITKIKTGFGTGGWQLAALNICSKAARKPLIADGGIRTHGDIAKS
                     IRFGASMVMIGSLFAAHEESPGETVELDGKQYKEYFGSASEFQKGEHKNVEGKKMFVE
                     HKGSLMDTLKEMQQDLQSSISYAGGKDLKSLRTVDYVIVRNSIFNGDRD"
     gene            16193..17209
                     /locus_tag="RFE25_001046"
     CDS             16193..17209
                     /locus_tag="RFE25_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001789887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HDU2816134.1"
                     /translation="MKKFIVTVVAFLSIIIIAPITEFKPFIHLQNEVRQYIDIHINKE
                     TISAENKLDTPKKQQFAFNNIQMNMSKSDVEKTLNKPKRVTFNEYGTKWYTYYDDDYN
                     NFIMISYMKDKVNALYTNQNIITSKSKIKYNTPKSVVRQRLGEPETEIVKGRVRYEQN
                     NKEYDVFHKNHIYTTVFYDKHRRNNVTAVLQVSDAMENRLKEQYGAPSKSLADSFELQ
                     NFDLVNAERKQHQLSTLKYSKQNSETARKHSKDMAKNHYFDHTNLKGQSPFDRLKKDG
                     ITFNSAGENLAYGQVSSIYAHQGLMNSIGHRKNILNDTFKILGVGVDFNDEKQPFWTE
                     NYTG"
     gene            complement(17589..18212)
                     /gene="lexA"
                     /locus_tag="RFE25_001047"
     CDS             complement(17589..18212)
                     /gene="lexA"
                     /locus_tag="RFE25_001047"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDU2816135.1"
                     /translation="MRELTKRQSEIYNYIKQVVQMKGYPPSVREIGEAVGLASSSTVH
                     GHLSRLEEKGYIRRDPTKPRAIEIVSDQTNDNINMEETIHVPVIGKVTAGVPITAVEN
                     IEEYFPLPEHLTSTHNSDIFILNVVGDSMIEAGILDGDKVIVRSQTIAENGDIIVAMT
                     EEDEATVKRFYKEKNRYRLQPENSTMEPIYLDNVAVIGKVIGLYREM"
     gene            18355..18588
                     /locus_tag="RFE25_001048"
     CDS             18355..18588
                     /locus_tag="RFE25_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816136.1"
                     /translation="MFYNKYKNVSTYIIIFLVSSAAFAIFLLSANVSAHSEQVYEMTD
                     HQIKNNTINKAYEHKDPTNNGEQRDGKVFALIN"
     gene            18725..18964
                     /locus_tag="RFE25_001049"
     CDS             18725..18964
                     /locus_tag="RFE25_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDU2816137.1"
                     /translation="MSNSDLNIERINELAKKKKEVGLTQEEAKEQTALRKAYLESFRK
                     GFKQQIENTKVIDPEGNDVTPEKIKEIQQKRDNKN"
     gene            19085..21073
                     /gene="tkt"
                     /locus_tag="RFE25_001050"
     CDS             19085..21073
                     /gene="tkt"
                     /locus_tag="RFE25_001050"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001661967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDU2816138.1"
                     /translation="MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWT
                     RHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVSGSLELEELKQFRQWGSKTPGHP
                     EYRHTDGVEVTTGPLGQGFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLM
                     EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKD
                     GNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFEN
                     YGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAETYPELAEEFKLAISG
                     KLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDAT
                     DYSSETPEGKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIM
                     GLNATFIFTHDSIAVGEDGPTHEPIEQLAGLRAIPNMNVIRPADGNETRVAWEVALES
                     ESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSEVSLAVE
                     AAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVG
                     TAGKVIAIDGFGASAPGDLVVEKYGFTKENILNQVMSL"
     gene            21351..21593
                     /locus_tag="RFE25_001051"
     CDS             21351..21593
                     /locus_tag="RFE25_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HDU2816139.1"
                     /translation="MATWLAIIFIVAALILGLIGGFLLARKYMMDYLKKNPPINEEML
                     RMMMMQMGQKPSQKKINQMMTMMNKNMDQNMKSAKK"
     gene            21580..21678
                     /locus_tag="RFE25_001052"
     CDS             21580..21678
                     /locus_tag="RFE25_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816140.1"
                     /translation="MRKSKFAIDRGYFPDMEMASFYNQINKNKYVY"
     gene            21772..22239
                     /locus_tag="RFE25_001053"
     CDS             21772..22239
                     /locus_tag="RFE25_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdC family protein"
                     /protein_id="HDU2816141.1"
                     /translation="MLYLIFSIIVALFMGTIVIVIRMKAQNYPVNEKKIVLPPFFMAT
                     GALMYVVPYFRLTGSEMLEAFIIGLLFSTVLIWTSRFEVKGTEIYMKRSKAFPVILIS
                     LLIIRTVMKIFISNEIDPGELGGMFFLLAFCMIVPWRAAMLYKYKKLKKTLIN"
     gene            22363..23484
                     /locus_tag="RFE25_001054"
     CDS             22363..23484
                     /locus_tag="RFE25_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDU2816142.1"
                     /translation="MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIV
                     IAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIMISGNHDGKERLNYGASWFEHNQ
                     LFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPE
                     IDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIE
                     DDKIKYSGSLLQYSFSEAGQAKGYRRLTINDGIINDVFIPLKPLRQLEIISGEYNDVI
                     NEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNETFNYNEENNAIEISE
                     KDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED"
     gene            23488..26517
                     /locus_tag="RFE25_001055"
     CDS             23488..26517
                     /locus_tag="RFE25_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDU2816143.1"
                     /translation="MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIF
                     DAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNHRIYKVHRQGPYIKEGN
                     TTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFL
                     ISNSREKQGILRTLFDSEKFEAIREILKEELKKEKAQIENRYQQIDLLWQEIESFDDD
                     KIKGLLELATQQIDKLIENIPLLQARSKEILAFVNESKETAIKEYEIIEKKTLENNIL
                     KDNINQLNKNKIDFVQLKEQQPEIDEIEAKLKLLQDITNLLNYIENREKIETKIANSK
                     KDISKTNNKILNLDCDKRNIDKEKKMLEENGDLIESKTSFIDKTRVLFNDINKYQQSY
                     LNIECLITEGEQLGDELNNLIKGLEKVEDSIGNNESDYEKIIELNNAITNINNEINII
                     KENEKAKAELDKLLGSKQELENQINEETTIMKNLEIKLDHYDKSKLDLNDKESFISEI
                     KSAVKIGDQCPICGNEIQDLGHHIDFDSIAKRQNEIKEIEANIHAIKSNIAVHNSEIK
                     FVNEKISNINIKTQSDFSLEVLNKRLLENENALNNQRDLNKFIEQMKEEKDNLTLQIH
                     NKQLRLNKNESELKLCRDLITEFETLSKYNNITNFEVDYKKYVQDVNQHQELSKEIED
                     KLMQLSQRKLIEQNNLNHYENQLETYNNDLELNEQSIEMEMSRLNLTDDNDINEIIAW
                     RGEQEELEQKRDTYKKRYHEFEMEIARLESLTKDKELLDSDKLKDEYEQKKEKMNTLI
                     DEYSAVHYQCQNNINKTQSIVSHINYLNQELKDQQEIFQLAEIVSGKNNKNLTLENFV
                     LIYYLDQIIAQANLRLATMSDNRYQLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLS
                     GGETFQSSLALALGLSEIVQQQSGGISLESIFIDEGFGTLDQETLETALDTLLNLKST
                     GRMVGIISHVSELKNRIPLVLEVKSDQYQSSTRFKRN"
     gene            complement(26588..26950)
                     /gene="mscL"
                     /locus_tag="RFE25_001056"
     CDS             complement(26588..26950)
                     /gene="mscL"
                     /locus_tag="RFE25_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDU2816144.1"
                     /translation="MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIG
                     KIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEAVV
                     EENVVLLTEIRDLLREKK"
     gene            27154..28800
                     /locus_tag="RFE25_001057"
     CDS             27154..28800
                     /locus_tag="RFE25_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HDU2816145.1"
                     /translation="MNSSSPENPNGKKYSPVFIYSAIVVAIVVLLGAFLPEQFNYVTN
                     NIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISWFAMLFS
                     AGMGIGLVFYGAAEPMAHFATPPTADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALA
                     LAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQIN
                     GGLHYLFNVPNNTFVQAIIIIVVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAAL
                     IVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPQKREWMSSWTLYYWGWWLSWSPF
                     VGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGIETGKKHKEIFDMTPETQ
                     LFGVFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTTFGSLNPSSMVKVVWGI
                     SQALIAFVLLLAGGGNGAEALNAIQSAAIISAFPFSFVVILMMVSFYKDANQERKFLG
                     LTLTPNKHRLQEYIKSQQEDYESDILEKRQSRRNIEKKDN"
     gene            29747..32452
                     /gene="acnA"
                     /locus_tag="RFE25_001058"
     CDS             29747..32452
                     /gene="acnA"
                     /locus_tag="RFE25_001058"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HDU2816146.1"
                     /translation="MAANFKEQSKKHFDLNGQSYTYYDLKAVEEQGITKVSNLPYSIR
                     VLLESLLRQEDDFVITDDHIKALSQFGKDGNEGEVPFKPSRVILQDFTGVPAVVDLAS
                     LRKAMDDVGGDITKINPEVPVDLVIDHSVQVDSYANPEALERNMKLEFERNYERYQFL
                     NWATKAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMI
                     NGIGVLGWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELR
                     KKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKYMKLTGRSD
                     EHIALVKEYLKQNHMFFDVEKEDPNYTDVIELDLSTVEASLSGPKRPQDLIFLSDMKS
                     SFENSVTAPAGNQGHGLDKSEFDKKAEINFKDGSKATMKTGDIAIAAITSCTNTSNPY
                     VMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQPYLDDLGFNLVGYG
                     CTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKANYLASPQLVVAY
                     ALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPELFIEEYNNVYN
                     NNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEPGTIVPLNGLRVMGKFGDSVT
                     TDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIRIKNQLA
                     PGTEGGFTTYWPTNEVMPIFDAAMKYKEDGTGLVVLAGNDYGMGSSRDWAAKGTNLLG
                     VKTVIAQSYERIHRSNLVMMGVLPLEFKKGESADSLGLDGTEEISVNIDENVQPHDYV
                     KVTAKKQDGDLVEFDAMVRFDSLVEMDYYRHGGILQMVLRNKLAQ"
     gene            32632..33099
                     /locus_tag="RFE25_001059"
     CDS             32632..33099
                     /locus_tag="RFE25_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDU2816147.1"
                     /translation="MIYSITEIEARYAETDKMGVIYHGNYATWFEVARLDYISKLGFS
                     YADMEKQGIISPVTDLNVNYKKSIFYPEKVKVKTWVEKYSRLRSVYKYEIFNEKGELA
                     TTGSTELICIKEDTFKPIRLDRYFPDWHEAYSKVQTLNNEGKTVEIMDGIDSL"
     gene            complement(33306..33602)
                     /locus_tag="RFE25_001060"
     CDS             complement(33306..33602)
                     /locus_tag="RFE25_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HDU2816148.1"
                     /translation="MQIELTDAAVTWFKNELELPENNKVLVFFVRYGGEFQLKQGFSP
                     AFTVEPKEDVDIGYEQQYDDLNVVVAEKDLWYFEDDHIIVNVVDHEDEISYSTK"
     gene            complement(33978..34586)
                     /gene="plsY"
                     /locus_tag="RFE25_001061"
     CDS             complement(33978..34586)
                     /gene="plsY"
                     /locus_tag="RFE25_001061"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDU2816149.1"
                     /translation="MMIIVMLLLSYLIGAFPSGFVIGKLFFKKDIRQFGSGNTGATNS
                     FRVLGRPAGFLVTFLDIFKGFITVFFPLWLPVHADGPISTFFTNGLIVGLFAILGHVY
                     PVYLKFQGGKAVATSAGVVLGVNPILLLILAIIFFIVLKIFKYVSLASIVAAICCVIG
                     SLIIQDYILLVVSFLVSIILIIRHRSNIARIFRGEEPKIKWM"
     gene            34792..36783
                     /gene="parE"
                     /locus_tag="RFE25_001062"
     CDS             34792..36783
                     /gene="parE"
                     /locus_tag="RFE25_001062"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDU2816150.1"
                     /translation="MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEI
                     VDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMPTGIHKSGKPTVEVIFTVLHAGG
                     KFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGSIYHQSFKNGGSPSSGLVKKGK
                     TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEH
                     YHYEEGIKEFVSYVNEGKEVLHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVR
                     TKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREGLTAVVSVRIPEELL
                     QFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKA
                     REDARSGKKNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAIL
                     PLRGKVINTEKARLEDIFKNEEINTIIHTIGAGVGTDFKIEDSNYNRVIIMTDADTDG
                     AHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTDEELNKLQK
                     ELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQ
                     PRREWIEKHVEFGMQEDQSILDNSEVQVLENDQFDEEEI"
     gene            36783..39185
                     /gene="parC"
                     /locus_tag="RFE25_001063"
     CDS             36783..39185
                     /gene="parC"
                     /locus_tag="RFE25_001063"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDU2816151.1"
                     /translation="MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRR
                     ILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDFSVYGAMVRLSQDWKLRHVLIEM
                     HGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRF
                     PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGG
                     IIQGIDGIKKAYESGKGRIIVRSKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDEL
                     RADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNSDLQISYNFNMVAIS
                     DGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIEL
                     IRSSKNKRDAKENLIEVFEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQL
                     RHILDNHDALLNVIKEELNEIKKKFKSERLSLIEAEIEEIKIDKEVMVPSEEVILSMT
                     RHGYIKRTSIRSFNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLFIPVHKL
                     ADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKT
                     TRFNKPLIATKVKENDDLISVMRFEKDQLITVITNKGMSLTYNTSELSDTGLRAAGVK
                     SINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKILQVAKRAQRGITLLKELKKN
                     PHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMY
                     IS"
     gene            39435..40895
                     /locus_tag="RFE25_001064"
     CDS             39435..40895
                     /locus_tag="RFE25_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDU2816152.1"
                     /translation="MKDFDSLIPGWFKEFVHVGTDLIWSQYLIGLLLTAGFFFTISSK
                     FVQLRMLPEMFRALVERPETLEDGKKGISPFQAFAISAGSRVGTGNIAGVATAIVLGG
                     PGAVFWMWVIAFIGAASAFIEATLAQVYKVHDKDGGFRGGPAYYITKGLNQKWLGIVF
                     AILITITFAFVFNTVQSNTIAESLNTQYNISPVITGIILAIVTAIIIFGGVRSIATLS
                     SLIVPIMAIIYIGMVLVILLFNLDQIVPMIGTIIKSAFGIEQVTGGAVGAAVLQGIKR
                     GLFSNEAGMGSAPNAAATAAVPHPVKQGLIQSLGVFFDTMLVCTATAIMILLYSGLKF
                     GDNAPQGVAVTQSALNEHLGSAGGIFLTIAVTLFAFSSVVGNYYYGQSNIEFLSTNRV
                     ILFIFRCLVVVLVFVGAVVKTETVWNTADLFMGLMAIVNIISIIGLSNVAFALMKDYQ
                     KQKKEGKNPVFKPENLEINLFGISAWGANKYKNSDK"
BASE COUNT        14936 a         5740 c         7461 g        13172 t
ORIGIN      
        1 ccaatgctaa gtttgttttt cttttatagt gcttttgccg ttccatttac ttttaaaaat
       61 aatgttaaaa aaacggcaac taatcttttc atactaacaa tgattatatg tacaataata
      121 acgtacttat tgtataacaa ctattttgtt gcaatgatgg tttattatgt cgttatatcg
      181 ttaataatgc tagataattt taaaaaaatg aaaaaccgtg aatatcaaaa agaaatagca
      241 gaaaaaaata gacatattaa tacattaatt gctgaacaag agcgacatag aattggtcaa
      301 gacttacatg atacgttagg gcatgtgttt gcaagtttat cattaaaatc agaattagct
      361 tataaactaa tagatactga tgtagaaaaa gtaaaagctg aattattagc aattaataaa
      421 ttatctcgtg aatcattgaa caaagttcga gaaattattg atgatgtaaa attaccatca
      481 tttattgaag agattgatag tatacgtaaa gttttaaaag atgctgatat tgattttaca
      541 tttgaaaata aagaattagc gcaagtatta agtcctacta aacaatctat gttagttatg
      601 attacgcgtg aagcgataaa taatgttatt aaacatgcaa atgcttcaaa agttcatggt
      661 aaattaaaaa ctgtaaacaa tcataaatta ctgcttatga ttgaagatga tggcaaaggt
      721 atcgatagtg attgtgaggt gaaaagtatt tcacagcgtg tacaacattt aaatggaact
      781 ttagcagtcg actcaacaaa tggaactaaa ataatcattg aaatctcaac aggaggaata
      841 gcatgacatc tttaattatt gcagaagatc aaaatatgtt acgacaggca atggttcaat
      901 taattaaact acatggtgat tttgaaattt tagcagatac tgataatggt ctcgatgcaa
      961 tgaaacttat tgaagaatat aatcctaacg ttgttatttt agatatagaa atgccaggca
     1021 tgactggact tgaagtttta gcggaaatta gaaaaaagca tttgaatatt aaagtgatta
     1081 ttgtaacaac ttttaaaaga ccgggatact ttgaaaaagc agttgtgaat gatgtggatg
     1141 catatgtttt aaaagaacgt tctatagaag aattggtgga aaccattaat aaagtaaata
     1201 acggagagaa agaatatagc gccacattga tgacttcatt ttttgtagat aaaaacccat
     1261 taacgcccaa agaacaaatt gtattaaggg aaattggcaa tggtttaagt agtaaagaaa
     1321 taagtgaaaa attatttttg acagatggaa cagttagaaa ttatacatct gttataattg
     1381 ataaattatt tgcagataat cgttttgatg cttggaaaaa ggcaaatgaa aaaggctgga
     1441 tctaaataca aacaaaaaag tattgagtgt tttgatttaa gagacttgga aagtgagtca
     1501 ataatcaaaa tcttactcaa tacttttatt ttggtactcg caatttagat ttgttaacta
     1561 attttttcgc ttattataaa acgaaacaat caagtaaacg ataaagccta caaagatacc
     1621 caataaaata gatagtactg ccgtcactat taatggtaat ttgaaaaata tttgtaggaa
     1681 aataccaatg ataattgcga taattactgc aattaatgtg actgtatttt catttgaaat
     1741 gttcatttat tttcactcct taacaataac attatatcat gctatagctt tccaaaatat
     1801 tgaaatatgt agatatggct attgacgata tttcttaact tttatatgat taatcggaat
     1861 gaaaaaagag aagtaggtgg caatatgaag tcaaataaat cgcttgctat gattgtggta
     1921 gccatcatta ttgtaggtgt attagcattt caatttatga atcatacggg tcctttcaaa
     1981 aaggggacga atcatgaaac tgtacaagat ttaaatggta aagataaagt acatgttcaa
     2041 agagttgtgg atggtgatac atttattgca aatcaaaatg gtaaagaaat taaagttagg
     2101 cttatagggg ttgatacgcc agaaacggtg aaaccgaata cgcctgtaca accatttggc
     2161 aaagaagcat caaattatag taagaagaca ttaacaaatc aagatgttta tttagaatat
     2221 gataaagaaa aacaagatcg ctatggtaga acattggcgt atgtatggat aagtaaagat
     2281 cgtatgtaca ataaggaatt agtggaaaag ggacttgcta gagagaagta tttttcacca
     2341 aatggcaaat atagaaatgt atttatagaa gcacaaaata aagctaaaca acagaaatta
     2401 aatatttgga gtaaataatt aaataggtga ttatatatat taaagtaaaa tatacttgaa
     2461 gcatcgattt attattacca taactttata tataaagaaa taatttaaag gcataataac
     2521 catagtgcgt atcgagcgta atggattatt atgcctttga ttttacttga atatagctgt
     2581 gatttgatca acctgttctt tatttaaagg gtgtttagat agctctatgg cttcgctaat
     2641 aatacgtcgt aatgaagatt ttgttgaaac ggtatcaaca tatttatctc tttcttcaga
     2701 accttgaatg atattaactg taccatcact aaagtaaata acaccggtac tttggacttt
     2761 aaagttaaag ttttgttcaa tatgatcctt taatgcttta gcattatttg ctgctaattg
     2821 atatggatca taatcataaa aatcataaat aacacgattt ggttgaactg tttctgtaaa
     2881 agtatagata gactttcttg atgaattaaa ctgatcatga tattgctggc taatgtaatg
     2941 accgacaact ttttcaatat tactattgct catttctgta tcatgctcat caggtacatc
     3001 aaagtgataa aatgtttttt caccccaact ttttacatca acgtttatta aaccgatatc
     3061 tgaaacaatg ataaaatcaa atgaacgtgc atactcgaaa aacggatgtt tagtagctaa
     3121 attgcttgta acgataatat cgtaatattt taatttacca ttttcgagat agctatctaa
     3181 aatcttgcgt aattctcttt tagcattttt gtatgcatgg tgtccaacat cattattaga
     3241 actcagcatt tgacttctta attcagcatt ttctgcactt aatgctttat tctttttaat
     3301 aagttgcttt cttgcataaa cttcggtatc tattttacta ttactatacc tttgatttaa
     3361 aactaatata ccaattaatg ctacaatgat aatgataagt acaacataaa aagacatttt
     3421 ttcaccaatc ctttttgact tctttaactt tgtatacaat aataattaat aaagattaat
     3481 tgttattcaa tttcccacat ttttattagt tgattttagt tcatcattgt tataatcaaa
     3541 ttataaactg acagatattg atgttcaatg aatatgacgt gaaagattcg tgaattcaag
     3601 tttatgtcga atttatgtta taacggtcat ttaaatgaca gaattaggtc actcatagta
     3661 ttttgaagat tgaattcatt aattttaaaa tgtataatga tatttgtgaa agcgcttgct
     3721 taggaggtgt atttgagagt gaatgaaatg aatgctaaag aacaattagt ggacaattta
     3781 atgaaaacat catcgcaatt atttaaattt cacggtgaag ttgccatgca gcttttctta
     3841 aatgatgaat taaaattacc ttctattgtt gaaatatgcg tggaacgtaa gcgtttaagt
     3901 gatattgtga aagttattcc gcaatcatat gcgttactat acatagataa gcaagatcaa
     3961 gcaatagcta aagaagattt atcactttca aaaattgcaa aagtttatgt gcaatatgat
     4021 gatacaacaa taatgagtat tttcgtttat gatgtagtaa acgatgaatg gatttttaga
     4081 ttggatccga atatacgtat acctaagagt aacatatact tccatagttt aaattgggat
     4141 gtggattata ttaaaccgga gatcgttcta atgtatgatc taatgcaaca ccatcagtat
     4201 catcattatt ccaattataa acgagtcata gatgcattaa gctactatca attttttatt
     4261 ttaaaatttg tagtaggtga gcaacgtatt aaggatgcaa tccagagaac aataaataat
     4321 taagaaaaag caattcataa cgcagttgaa tacatgtgtt acgaattgct tttatattag
     4381 tttttatcac acaagttttt taatgcaacc ccgtgatagc aaaactcata tgtagataat
     4441 acagcttttt cagcatcatc tacatgaatt ccaaacatca tcgagatttc cgaagcacct
     4501 tggttaatca tttttaagtt aatttttgat tcagctaagg catgtgtaat tttatttgca
     4561 gtaccgatga ctttattcat accttcgccg acaatcatta atattgctaa atcatgctca
     4621 atacttagct catcaacatc acatttttga cgaatttcat ttaatacttt tgtttcttta
     4681 ttttgaattt gttttgaacg cataacgata ctgatagtat caatacctga aggcatatga
     4741 tcaaatgaaa tattattatc ctctaagaca cctaatatct ttctagtaaa gccgacttgt
     4801 ctattcatta aatacttttt gatattaatg acagtaaaat ctttatcaca acttataccg
     4861 ctaatcacat ttttcgcatt tatttctcta tcatgcacta taaatgtacc cttatcttga
     4921 gggcggttcg tatttttaat caccacaggg atgcgatctt tataaagtgg ttgtaaggct
     4981 tcatcatgga aaacactaaa accagcataa gataattcac gcatttctcg ataagtgatt
     5041 tcttcgatta attcaggatc tttgatgata tttggattag ctttataaat accagacaca
     5101 tcggtgaaat tttcataaat tgtggctcta acaccacttg atatgatggc gccagttata
     5161 tctgatccgc cacgtggaaa tgtaactata tatccttcat gagatacgcc aaaaaatcct
     5221 gggataatta gtttttcatc ataatctctt aattttttaa tttcagagta agcactatct
     5281 aatatttgtg cttcttgtgg gacgtcagta acaaaaatac ccgcttcctt cggtgatata
     5341 tattttgttg gtataccttg actattatta tataaagcta tcaattgcgc attaaaatct
     5401 tcaccacaag aaagtaatgc atctaatagt ctctttggtt cgttttttaa ttgattaata
     5461 taatgttcca aagtcacatc tatcgtccgt aaaatacttt catccatttg caattctttt
     5521 acaatatcat cataacgctg aataatttct ctttttttat catgataatc aagatgatta
     5581 atgacctttt catataatct gattaacaaa tcagttgttt taatatcatt atcatgtctt
     5641 ttacctggag cagaaacgat aacaatcttt cgctctggat cagaattaac aatatttaaa
     5701 acctttttaa tttgagtagc attggagacg gagctaccac cgaatttgga aactttcata
     5761 gtgcatgcca acctttctaa aaaatcagaa aattgtattc agttttgtaa gtaagaatga
     5821 tattatgtat ttatattttg aatattacga actttacaaa aataaagaat aattctatac
     5881 tatactatca tctagtgttt ttcaataata catttgtttt tctcaaaagc acaaacggag
     5941 gtacataaaa tgaaaaaatt aaatatagca ttattaggat taggtactgt cggatctggt
     6001 gttgttaaaa tcatcgaaga gaaccgacag caaattcaag atacattaaa taaagatatt
     6061 gtcataaagc atattcttgt tcgagataaa tctaaaaaga gaccgctaaa tattagccaa
     6121 tatcatttaa ctgaagatgt taatgaaatt ttaaatgatg attcattaga tattatcgtt
     6181 gaagtcatgg gaggaattga accaactgta gattggttaa gaacagcact taaaaataaa
     6241 aaacatgtta ttaccgcaaa taaagattta ttagcagtac atcttaaact tttagaagat
     6301 ttagcagaag aaaatggtgt agctttaaag tttgaagcga gtgtagcagg tggtattccg
     6361 atcgtaaatg ccataaataa tggtttgaat gcgaataata tttcaaaatt tatgggaatt
     6421 ttaaatggta cctctaattt tattttatct aaaatgacta aagagcaaac gacatttgag
     6481 gaagcacttg atgaagcgaa aagacttggt tttgctgaag cggatccaac tgatgatgta
     6541 gaaggggtag atgcagcgcg taaagttgtc attacatcat atttatcatt taaccaagtc
     6601 attaaattaa acgacgttaa acgaagagga attagtggcg taactttaac tgatattaat
     6661 gtagccgatc aactggggta taaaattaaa ttgattggta agggaatata tgaaaatggc
     6721 aaagttaatg catcggtaga accaacgtta attgataaaa agcatcaatt agcagctgta
     6781 gaggatgaat ataacgcgat ttatgttatt ggtgatgccg ttggtgacac gatgttttat
     6841 ggaaaaggag caggcagttt agcaacaggt agtgccgttg tcagtgattt attgaatgta
     6901 gcattattct ttgaatcaga tttacacaca ttgccaccac attttgaatt aaagacagat
     6961 aaaacaaggg aaatgatgga ttcagatgca gaaattaata ttaaagaaaa atccaatttc
     7021 tttgtagtag tgaatcatgt caaaggttca attgaaaatt ttgaaaatga gttaaaggca
     7081 atattaccat ttcaccgatc attaagagtt gcaaattacg ataatcaatc atatgccgct
     7141 gttatagttg gattggaatc atcaccggaa gaattaatca ctaagcatgg atacgaagtt
     7201 gacaaagtat acccagtaga aggagtttaa ttataatgag aagatggcaa ggattagtag
     7261 aagagtttaa agcacattta ccagtaaatg aaaatacacc aaaattaaca ttgaacgagg
     7321 gaaatacacc actcattcat tgtgaaaata tgtctaaaat actaggtata gatttatatg
     7381 tgaagtatga aggtgccaat ccgacaggtt catttaaaga tcgcggtatg gtaatggctg
     7441 tgacaaaagc aaaagagcaa ggtaagaaaa ttgtaatatg cgcttcgact ggaaatacat
     7501 cagcgtctgc agcagcatat gcagcgagag caggtttaaa agctatcgtc gtaataccag
     7561 aaggtaaaat tgcattaggt aaattgtcgc aagcagtaat gtatggtgca gaaatcgttt
     7621 ctattgaagg aaactttgat gaagctttag aaattgtaaa agaaattgca aaaagtggcg
     7681 aaatagagct tgtaaactct gtcaatccat ttagaatcga agggcaaaag acaggctcat
     7741 ttgaaattgt acaacaatta gacggtgaag cacctgatat tttagcgatt cctgtaggta
     7801 atgcaggtaa tattactgca tattggaaag gctttaaaga atatcatgaa gctaaaggat
     7861 cacaattgcc gaaaatgttt ggcttccaag ctgaaggcgc atcaccaatt gttcaaaata
     7921 aagtcattaa aaatcctgaa acgattgcaa ctgctattcg aattggtaat cctgctagtt
     7981 gggataaggc gactaatgct cttaaagaat caaatggatt aatagatagt gttactgatg
     8041 atgaaattct agaagcatat cagttaatga caactaaaga aggtgtcttt agtgaaccag
     8101 caagtaatgc ttctattgca ggtttaatta aattgcatag acaaggtaaa ttacctcaag
     8161 gtaaaaaagt agttgctatt ttaactggta atggattaaa agatcctgat actgctattt
     8221 cactactaga taatccgata aagccattgc aaaatgataa agatagcatt atcgattata
     8281 ttaaaggagc tttataacat gtcgaatgtt ttggagttaa caattcctgc atcaacagcc
     8341 aaccttggag ttggctttga ttctataggt atggctttag ataaattttt gcatctgtct
     8401 gtaaaggaaa catcagggac aaaatgggaa tatattttcc atgatgatgc atctaagcaa
     8461 ttgcctactg acgaaacaaa ctttatttat catgtagcac aacaagttgc ttctaaatat
     8521 agtgttgact tgcctatttt atgtatcgaa atgagaagtg atattccatt ggcaagaggg
     8581 ttaggttcgt cagcttctgc tttagtagga gctatatata tcgcaaatta ttttggtgat
     8641 atccaactgt ctaaacatga ggtattacaa ttagcgactg aaatcgaagg acatcctgat
     8701 aatgttgcgc cgaccattta tggtggttta atcgctggat tttataatga tgtctcgaaa
     8761 gaaacgtcag ttgcacatat cgacatacca gacgtggatg tgattgtaac gataccaact
     8821 tatgaactaa aaacagaagc atcaagacgt gctttaccac aaaaattaac acatagtgaa
     8881 gcggtaaaaa gtagtgcaat tagtaataca atgatttgtg cattagcaca gcacaattat
     8941 gaattagcag gtaaactcat gcaacaagat ggctttcatg aaccgtatcg tcagcattta
     9001 attgctgaat ttgatgaagt gaaaacaatt gctagtcaac ataatgccta tgcaactgta
     9061 attagtggtg ctggaccaac tattttaata tttagtcgta aagaaaatag tggggaattg
     9121 gttcgctctt taaatagtca ggtagtatca tgccattctg aattggtcga tattaatatc
     9181 agtggtgtta aagaacgaat tgtataccaa tagacgcttt atattgtaaa atagtattaa
     9241 atgcagaata gagaggagat ttaatgcgat atgacaaatt ataaagttgt cgttttagat
     9301 atggatgaca cattgctaaa ttcagataat gtgatatcag aagaaactgc aaattattta
     9361 acagcaattc aagatgaagg ttattatgtt gttttagcat ctggtagacc tactgaaggt
     9421 atgattccaa ctgctagaga tttaaaatta cctgaacatc atagctatat tattagttat
     9481 aacggtagta aaacgattaa catgactaat gaagaagtag aagtaagtaa atcgattggt
     9541 aagcaagatt tcgatgaaat tgtagattat tgtcgagaca gaggcttttt cgttcttaca
     9601 tatcatgatg gtcaaattat ttacgacagc gaacatgagt atatgaatat tgaagcagaa
     9661 ttaacaggtt taccgatgaa acgtgttgat gatatcaaag cgtatattca aggcgatgta
     9721 cccaaggtca tgggtgtaga ttatgtagcg aatattacag aagctagaat tgatttgaat
     9781 ggtgtgttca atgataatgt agatgctacg acaagtaagc cattcttctt agaatttatg
     9841 gccaaagatg tttcaaaagg taatgcaatt aaagcgttat gtcacaaatt gggatattcg
     9901 gtggatcaag tcattgcttt tggtgatagt atgaatgata aatcaatgtt tgaagtcgca
     9961 ggtctagcta ttgctatggg gaatgcatca gatgaactta agcaatatgc agatgaagtt
    10021 acgttggacc ataatgaaaa tggtattcca catgcgctca aaaaattgtt ataaatttta
    10081 aaataagcct taacacatga tatttgaata agatatcttg tggttaaggc tttttattta
    10141 tgtgaaaatg acttcagtta tactatggag gatttgaaat acatatttta gattagtaat
    10201 gatatcaaac gaatagagta aatgtatatt ttttgaataa atcaagtatt aactagtcac
    10261 ggaaggtagg taaataaatt tgatcattct gaataataac gaatgcatta aaaaatgcag
    10321 tgacaatcta acattaattg ttaaaatcac tgcaagcatc ttgattttat ttagctgttt
    10381 gtgtccagtc atgcttacct ctgaaacgtt ttacatgagc atatatttgg tcagcagtat
    10441 aatctaaatt tgtataaact gtaatactga acgctgattg gttttcagca aatgattctt
    10501 cggaaaataa ttcctttaag tgcgtaaata aatcattcat ttgtttatgg tttaaaccgg
    10561 gatattccct taaagttctc tttaataatt gtccgttctt ttcttctaat gcttgaacta
    10621 caataacaaa tctttcatct tgctttagta catcatcaaa taaatttgtt tgtccaatca
    10681 ttgaatttca cccctgaaaa gttattgtta tctatattat acacgatatg caaaatttct
    10741 aaaataaaga atggtaacat ggtaataata aaatataaaa agaatactag ttaatacact
    10801 ttatactaga aaaagatatt aaagtatatc tgctttacac cattaaaaag cggcaaatgc
    10861 tatagataat ctaaagcatc tgccgtgtaa gaatttattt atttttgatt gtcataatcg
    10921 tgtggtttta aattaattgt ttctagcttt acaaattttg ttttgtgaat gattttatga
    10981 ataaagtaaa tcaacgctag aatgattaaa ggtaaaaagt ttttaaaagc atttaaccat
    11041 tgatctttta aaatatattc aactgagcca ccaaatagca agaataatag tgtagtgatg
    11101 acaatgattg gtcctaatgg ataaaaaggt gctttatatg gtaggacctt attagggtct
    11161 tgaccttgtt ttttaatagc ttgtcgcaat cgtatttgtg accaaatgct tgatccccaa
    11221 acaactataa tcattgaacc aataatttca agtaaattaa aaacggcatt tgaattaaag
    11281 tttgcataaa taataacaat aacaacgact gcataagtag ttaataatgc tcttaaaggt
    11341 aacttagttg tcttgtttaa tttacttaaa aattggggtg cttttttgtc tgaacttaag
    11401 gaatacaaca ttctgcctgt tgtataaaca cctgaatttg cagcggataa taatgaagtt
    11461 aaaataaccg cgttgattac tgatgctgca aaggctatgc ctactctatc gaatacaatt
    11521 gtaaatgggc tttgacttat tgaactactt gctcttaata atgatggatc tgtgtacgga
    11581 ataattacac caattactgc aattgataag acatagaata aaagaatacg ccaaaatact
    11641 tgtttaattg ccttaggcat agacttttta gggtcatctg attcaccagc agttactgct
    11701 actacttctg taccaccaac cgaaaatccg gcgactaata atacgcctaa gaaaccagag
    11761 ataccaccaa caaacggtgc ttggcctttt gtatagtttt caaatccata tgtatgacca
    11821 cctaagatac cgaaaatcat taaaaagcca aaaataacga atacgataat tgttaacact
    11881 ttaatcaatg ataaccaaaa ctcagtttct ccaaatgatt ttacagaaaa aatgtttaat
    11941 aatagtaaaa ttgtaataaa gattaagctc caagtaatgg ggtggaaaaa tttaaatgtg
    12001 tcccagaaat aaagcacatt tgacgctact atgacatcaa cacttgtaac taatgaccac
    12061 aatgcccaat acaaccatcc catggtaaag ccaagagatg agtcaataaa gcgtgttgaa
    12121 taagagctga atgaacctga tactggataa aatgttgcca actctccaat tgatgacatt
    12181 aagaaatata gcatgacacc aataacaaga taagcgagta tagcgcctcc aggaccagct
    12241 tgagaaatga tattaccagt agctacaaat agaccagtcc caattgcacc acctatagca
    12301 atcatggaaa tgtgtcttga gttaagacta cggttcattt tattatcttc catatttagt
    12361 ctcccatcta tttaaatata cccattattg taagcttttt aagtgtacta ttcaataact
    12421 atttagtact gtaaagcgaa aaaattaaaa ttttctgatt ttttaatcat cttgagcatg
    12481 tttaattgta attttgatgg ggttaaatta taatatgtat taaattataa ttattataaa
    12541 ttgtggaggg atgactatgt cacaacaaga caaaaagtta actggtgttt ttgggcatcc
    12601 agtatcagac cgagaaaata gtatgacagc agggcctagg ggacctcttt taatgcaaga
    12661 tatttacttt ttagagcaaa tgtctcaatt tgatagagaa gtaataccag aacgtcgaat
    12721 gcatgccaaa ggttctggtg catttgggac atttactgta actaaagata taacaaaata
    12781 tacgaatgct aaaatattct ctgaaatagg taagcaaacc gaaatgtttg cccgtttctc
    12841 tactgtagca ggagaacgtg gtgctgctga tgcggagcgt gacattcgag gatttgcgtt
    12901 aaagttctac actgaagaag ggaactggga tttagtaggg aataacacac cagtattctt
    12961 ctttagagat ccaaagttat ttgttagttt aaatcgtgcg gtgaaacgag atcctagaac
    13021 aaatatgaga gatgcacaaa ataactggga tttctggacg ggtcttccag aagcattgca
    13081 ccaagtaacg atcttaatgt cagatagagg gattcctaaa gatttacgtc atatgcatgg
    13141 gttcggttct cacacatact ctatgtataa tgattctggt gaacgtgttt gggttaaatt
    13201 ccattttaga acgcaacaag gtattgaaaa cttaactgat gaagaagctg ctgaaattat
    13261 agctacagat cgtgattcat ctcaacgcga tttattcgaa gccattgaaa aaggtgatta
    13321 tccaaaatgg acaatgtata ttcaagtaat gactgaggaa caagctaaaa accataaaga
    13381 taatccattt gatttaacaa aagtatggta tcacgatgag tatcctctaa ttgaagttgg
    13441 agagtttgaa ttaaatagaa atccagataa ttactttatg gatgttgaac aagctgcgtt
    13501 tgcaccaact aatattattc caggattaga tttttctcca gacaaaatgt tgcaagggcg
    13561 tttattctca tatggcgatg cgcaaagata tcgattagga gttaatcatt ggcagattcc
    13621 tgtaaaccaa cctaaaggtg ttggtattga aaatatttgt ccttttagta gagatggtca
    13681 aatgcgcgta gttgacaata accaaggtgg aggaacacat tattatccaa ataaccatgg
    13741 taaatttgat tctcaacctg aatataaaaa gccaccattc ccaactgatg gatacggcta
    13801 tgaatataat caacgtcaag atgatgataa ttattttgaa caaccaggta aattgtttag
    13861 attacaatca gaggacgcta aagaaagaat ttttacaaat acagcaaatg caatggaagg
    13921 cgtaacggat gatgttaaac gacgtcatat tcgtcattgt tacaaagctg acccagaata
    13981 tggtaaaggt gttgcaaaag cattaggtat tgatataaat tctattgatc ttgaaactga
    14041 aaatgatgaa acatacgaaa actttgaaaa ataaatttga tatgtagttt ctatattgcg
    14101 tagttgagca gtttatgata tcataataaa tcgtaaagat tcctaacaag agagggtgtt
    14161 taacgtgcgc gtaaacgtaa cattagcatg cacagaatgt ggcgatcgta actatatcac
    14221 tactaaaaat aaacgtaata atcctgagcg tattgaaatg aaaaaatatt gcccaagatt
    14281 aaacaaatat acgttacatc gtgaaactaa gtaattctta tcattcaaat acgacgattt
    14341 gaaaataaag cgggcttacc tattatattg gggagctcgc ttttttatga aatttttgtg
    14401 aagagtgatt aatggattga gtttcatcgg tagaacaata tatgattgta ttagttgtta
    14461 ctttattaaa atttgagaat atttatagaa ggaaatagat tactgatttt ataaagtcac
    14521 tttgttagcg aatgcttgaa agagtattta atatagtaga atttaaaatt tcaaagcgga
    14581 atttaataag tacgaagtaa ttctgggtat gttttataaa tgttcgataa tacactttaa
    14641 tcttaaatat gatggtttag aaaatgattt aacaaagaaa tgaaacttta ctgttgaatt
    14701 atgtgaggat tgtgttatta tataaatcgt aataattacg atttgataaa aagtgaggta
    14761 actatatatg gctaagaaat ctaaaatagc aaaagagaga aaaagagaag agttagtaaa
    14821 taaatattac gaattacgta aagagttaaa agcaaaaggt gattacgaag cgttaagaaa
    14881 attaccaaga gattcatcac ctacacgttt aactagaaga tgtaaagtaa ctggaagacc
    14941 tagaggtgta ttacgtaaat ttgaaatgtc tcgtattgcg tttagagaac atgcgcacaa
    15001 aggacaaatt ccaggtgtta aaaaatcaag ttggtaaaat caaatttcgc actttagccc
    15061 atttacaata tcaataaaac aatgtacagt atatacgaat gctataaact gaatgttttc
    15121 tcatattaat aaggaaacat tcggttttta atttgcattt aaaaataatt agtttttaaa
    15181 ggggctattt aaagtgaaaa tatttgatta cgaagatatt caattaatac ctaataaatg
    15241 catagttgaa agtaggtctg aatgtgatac aactatccaa tttggtccga aaaaattcaa
    15301 gctacctgta gttcctgcaa atatgcaaac agttatgaat gagaaattag cgaaatggtt
    15361 tgctgaaaat gattactttt atatcatgca tcgttttgat gaagaagcaa gaataccttt
    15421 tataaaacat atgcaaaatt caggcttatt tgcatctatt tcagttggtg taaagaaagc
    15481 ggaatttgat tttattgaaa agttagctca agaaaaatta atccccgaat atattacaat
    15541 agatattgcg catggtcact cagattcagt gataaacatg attaaacata taaaaaacca
    15601 tatacctgat agttttgtta ttgctggtaa tgttggtacg ccagaaggtg ttagagaatt
    15661 agaaaatgct ggtgctgatg ctaccaaagt cggtataggt cctggtagag tttgtattac
    15721 aaagattaaa acaggttttg gtactggtgg ttggcagtta gcggcattaa acatatgtag
    15781 taaagcagct cgtaaacctt tgattgccga tggtggtata agaacgcatg gcgacatcgc
    15841 taaatcaatt agatttggtg catcaatggt catgattggt tcattatttg cggcacacga
    15901 agaatcacct ggtgaaactg tagaacttga tggtaaacag tataaagaat attttggtag
    15961 tgcatctgaa tttcaaaaag gcgaacataa aaatgtagaa ggtaaaaaaa tgtttgtaga
    16021 acataagggt tcattaatgg ataccttaaa agaaatgcaa caagatttac aaagctcaat
    16081 ttcatatgcc ggtggaaaag acttgaaatc attacgtact gtagattatg ttattgttag
    16141 aaactctatt ttcaacggtg atagagatta atatttatag taggtgatgt aaattaaaaa
    16201 attcatagta actgttgttg cgtttttatc aattattatc attgcgccaa taacagaatt
    16261 taaaccattc attcatttac aaaatgaagt aagacaatat attgacattc acatcaataa
    16321 agaaacaatt tctgcggaaa ataaattgga tacaccgaag aaacaacaat ttgcctttaa
    16381 taatatacaa atgaacatgt cgaaatcaga tgttgagaaa acattaaata aaccaaaaag
    16441 agtgacattt aatgaatatg gtacgaagtg gtatacgtat tatgatgacg attacaataa
    16501 ttttataatg ataagttaca tgaaagataa agttaatgcg ttatatacaa atcaaaatat
    16561 aatcacttca aaatcaaaaa ttaaatacaa tacacctaaa tcggttgtaa ggcaaagatt
    16621 aggcgaacca gaaacagaga ttgttaaagg tagagtgcgt tacgaacaaa ataataaaga
    16681 atatgatgtt ttccataaaa atcacattta tacgacggta ttttatgata agcatcgacg
    16741 taataatgta acagctgttt tacaagtaag tgatgctatg gaaaatagat taaaagaaca
    16801 atatggagca ccttcgaaat cgcttgcaga tagttttgaa ctacaaaatt ttgatttagt
    16861 taatgctgaa agaaaacaac atcaattatc tacattgaag tattctaaac agaattctga
    16921 aactgctcgt aagcatagta aagatatggc caaaaatcat tattttgatc atacaaattt
    16981 aaaaggtcaa tcaccatttg atcgattgaa aaaagatggt attacattta actcagccgg
    17041 agagaattta gcatatggtc aagttagtag tatctatgca catcaaggat taatgaattc
    17101 tattggtcac agaaaaaata ttttaaatga tacgtttaaa atattaggtg ttggtgttga
    17161 ttttaatgat gaaaaacaac ctttttggac agaaaattat actggttaat gtttttggta
    17221 tgagtttaaa gggtaatgtt tgtctgtaag gaagtagata aacatgatga caacagataa
    17281 accaaaagat gcggatatac ttgaacgcgt caaagatata cttaataaaa aagaaagaaa
    17341 aaaataataa tggctcgctc ctgtaaatta ttacgggggc gagttttaat ttgtgtaaca
    17401 ttttgcagga atctgtaatt caaaatttat attaaagaat gagattatct aacaattcgc
    17461 aatttctgtt tgaactgaat ttagattaga ataaataaaa cctcttgaaa acgaaacttt
    17521 ttcaagaggt ccaaaattta taaaaatgag ggtttaacaa ttacgataat atataacggt
    17581 ttaaaatatt acatttcgcg gtacaaacca attactttcc caattacagc aacattgtcg
    17641 aggtaaattg gctccattgt actattttca ggttgtaatc gataacgatt tttttcttta
    17701 tagaagcgtt tgacagttgc ttcatcttcc tcagtcatag caacaataat gtctccattt
    17761 tctgctatgg tttgactgcg aacaattact ttgtctccgt ctaatatacc agcctcaatc
    17821 atactgtcgc ctacgacgtt taatatgaat atgtcgctat tatgtgtcga tgttaagtgt
    17881 tcaggtaatg gaaaatactc ttcaatattt tctacagcgg taataggaac acctgctgtg
    17941 actttaccaa taactggcac atgaatcgtt tcttccatat taatattatc atttgtttga
    18001 tcacttacaa tttctatagc acgtggtttc gttggatctc ttcttatata tcctttttct
    18061 tcaagacgtg aaagatgacc atgaacagtt gaactggatg ctaagccaac tgcttcacca
    18121 atttcgcgaa cactaggcgg ataacctttc atttgaacaa cttgtttaat atagttatat
    18181 atttcgcttt gtcgttttgt taattctctc atatataggc actccctaaa ttaatttaaa
    18241 tacagtatat cattaattca caaccaaaac aaacatttgt tcgttaaaat attgacacag
    18301 aacataagtt ctgataaatt acttatacaa acaaatgttc taggagtgga aatgatgttt
    18361 tacaataaat ataaaaacgt atcaacatat atcatcatat ttttagtttc aagtgcagct
    18421 tttgcaatat tcttgttaag tgcgaacgtt agtgctcact cggaacaagt gtacgaaatg
    18481 actgaccatc aaattaagaa caatacgata aataaagcat acgaacataa agaccctaca
    18541 aacaatggcg aacaaagaga tgggaaagtg ttcgctttaa taaattgata cattgtcaca
    18601 acgttatttt gcctattttt gcgaaatagc gtttttttat tacttttttg ctggtcttaa
    18661 atttgttata ttttgttaaa gtattataat gattgaataa acaaattgaa ggtaggtttt
    18721 ttaattgagt aattctgatt tgaatatcga aagaattaac gagttagcta aaaagaaaaa
    18781 agaagtagga ttaactcaag aagaagcaaa ggagcaaaca gccttaagaa aagcttatct
    18841 tgagagtttt agaaaagggt ttaaacaaca aattgaaaat actaaagtaa ttgatccaga
    18901 aggtaatgat gtaacacctg aaaaaattaa agagatacaa caaaaaagag ataataaaaa
    18961 ttaaatcaca aatctgtaaa gaattttctg acattataac ttgaaataag tattttactt
    19021 atctttttat tttaaaataa gttataatgt attttataaa attgaagaag ggaagataca
    19081 caagatgttt aatgaaaaag atcaattagc tgttgatacg ctacgtgcac taagtatcga
    19141 cacaatcgaa aaagcgaatt ctggtcatcc aggattacct atgggagctg ccccaatggc
    19201 ttacactttg tggacacgtc atctgaattt taatccacaa tctaaagatt acttcaatag
    19261 agaccgtttc gtattatcgg cagggcatgg ttcagcatta ttgtatagct tgttacatgt
    19321 ttctggtagt ttagaattag aagaattaaa gcaatttaga caatggggtt ctaaaacacc
    19381 aggccatcct gaatacagac atactgatgg tgtagaagtt actactggac cacttggaca
    19441 aggttttgct atgtcagtag gattagcttt agcagaagat cacctagcag ggaaatttaa
    19501 taaagaagga tataatgttg tagatcatta cacatatgta ttagcttctg acggtgattt
    19561 aatggaaggt atatcgcatg aagcagcttc atttgctgga cataataaat taagtaaatt
    19621 agttgtttta tacgattcaa atgatatttc attagatggc gaattaaaca aagctttttc
    19681 tgaaaacaca aaagctcgtt ttgaagcata tggttggaat tacttactag ttaaagatgg
    19741 taatgattta gaagaaattg ataaagcgat tactacagct aaatctcaag aaggaccaac
    19801 gattattgaa gttaaaacaa caatcggatt tggttcaccg aataaagcag gaactaatgg
    19861 tgttcatggg gcacctttag gtgaagttga aagaaaatta acattcgaaa attacggttt
    19921 agatcctgaa aaacgtttta atgtttcaga agaggtatac gaaattttcc aaaatactat
    19981 gttaaaacgt gctaatgaag atgaatctca atggaattca ttattagaaa aatatgcaga
    20041 aacatatcct gaattagcag aagaatttaa attagcgatt agtggtaaat tgcctaaaaa
    20101 ttataaggat gaattaccac gttttgaact gggtcataat ggtgcatctc gtgctgattc
    20161 tggtactgtt attcaagcaa tcagtaaaac tgtcccttca ttctttggtg gatcagcaga
    20221 ccttgctggt tcaaacaaat ccaatgtaaa tgatgcaaca gattatagtt ctgaaacacc
    20281 tgaaggtaaa aatgtgtggt ttggtgtacg tgaatttgct atgggtgctg ctgtaaatgg
    20341 tatggctgca catggaggtt tacatccata tggtgcaaca ttcttcgtat ttagtgatta
    20401 tttaaaacca gcgttacgtt tatcatcaat tatgggatta aatgcaacgt tcatcttcac
    20461 acatgattca attgcagtag gtgaagatgg tcctactcat gaaccaattg aacaattagc
    20521 tggattaaga gctattccaa atatgaatgt tatccgtcct gctgatggta atgaaacaag
    20581 agtagcatgg gaagttgcct tagaatctga atctacacct acttcattag tattgacacg
    20641 tcaaaactta ccggttttag atgtaccaga agatgtagtt gaagaaggcg ttcgaaaagg
    20701 tgcctataca gtttatggct ctgaagagac accagaattc ctattattag cttcaggttc
    20761 agaagttagt cttgcagttg aagctgctaa agatcttgaa aaacaaggta aatcagtgcg
    20821 tgttgtttca atgcctaact ggaatgcatt tgaacaacaa tctgaagaat ataaagaatc
    20881 agttattcca tcaagcgtaa caaaacgtgt tgcgattgaa atggcttcac cgcttggatg
    20941 gcataaatat gtaggtactg caggtaaagt tattgctatt gacggctttg gcgcaagtgc
    21001 acctggcgat ttagtagttg aaaaatatgg atttactaaa gaaaatatct taaaccaagt
    21061 tatgagctta taagaataat ttataaagcg agtatgttta gaagtctagg atgcataatc
    21121 ttaggcttct tttaaagtgt tgaaatttag agtatagcac ttaaactaca tcataagtga
    21181 taagttatga aagtatacta tttcagatta atctttaaaa gctctgttat aacagcatga
    21241 tttttgatat tatttttagt atcgatatta aaatacttga ataaactagt tcttgaaata
    21301 atgtgatgaa tttagtaaaa ttcagtagga taaagaaagc gggtgaaaca atggcaactt
    21361 ggttagcaat tatttttata gtagctgcat taattttagg tttaattgga ggtttccttt
    21421 tagctagaaa atatatgatg gactacttga agaaaaaccc accaatcaac gaagaaatgc
    21481 ttcgtatgat gatgatgcaa atgggtcaaa aaccttctca gaagaaaatt aatcaaatga
    21541 tgacgatgat gaataaaaat atggatcaaa atatgaagag tgcgaaaaag taaattcgca
    21601 attgatagag gctattttcc agatatggaa atggcctctt tttataatca aattaataaa
    21661 aacaaatatg tttattaaaa ttaaagttaa caaaatgacg aatagactga gaaatgctat
    21721 aattcatttt gtatgattta cagagagttt atttaacgag aaggtgtctg cgtgctctat
    21781 ttaatatttt caatcattgt agctttattt atgggaacta tagttatagt tattcgtatg
    21841 aaagctcaaa attatccggt aaatgagaaa aaaatagttt tgccaccgtt ttttatggcg
    21901 accggtgcat tgatgtacgt cgttccatat tttaggctaa caggatcgga aatgctagaa
    21961 gcctttataa ttggtttgct tttttctaca gttctaattt ggacttctcg atttgaagtc
    22021 aaaggtacag aaatttatat gaaacgatct aaagcatttc cagttatttt gatttcatta
    22081 cttatcattc gtactgtgat gaaaatattc attagtaatg aaatagatcc tggagaatta
    22141 ggcggcatgt tctttttatt agcattctgt atgattgttc cttggagagc agcaatgcta
    22201 tataaataca aaaaactaaa gaaaacatta atcaattaat tacttttaaa accacttgtg
    22261 atcgacttct aaatcagtca atgagtggtt ttaattttac ttgaaaaggt gaaatgatta
    22321 tattaaaata aaagcgaaca aatgttctat atggaggcag taatgaaaat tatacataca
    22381 gcagactggc acttagggaa aatattaaat ggcaaacagc ttttagaaga tcaagcgtat
    22441 attttagata tgttcgtaga aaaaatgaaa gaagaagaac ctgatatcat tgtgatagct
    22501 ggagatttat atgacacaac atatccaagt aaagatgcaa tcatgttatt agaacaagcg
    22561 attggaaagt taaatttaga actgcgtata ccaataatta tgattagtgg aaatcacgat
    22621 ggtaaagaga ggttaaacta tggggcgagt tggtttgaac ataatcagtt atttataaga
    22681 acagatttta catcgattaa ttcaccaata gagataaatg gggttaattt ttatacactc
    22741 ccttatgcta ctgtgagcga aatgaaacac tactttgaag atgacaccat tgaaacacat
    22801 caacagggaa ttacgcgctg tattgaaaca atagcaccgg aaattgatga agatgccgtc
    22861 aatattttaa ttagtcatct gactgttcaa ggtggaaaga catctgattc tgaaagacca
    22921 ttaactattg gaacggttga atcagttcag aaaggtgttt ttgatatatt tgattatgtc
    22981 atgctaggtc acttgcatca tccatttagt atagaagacg acaaaattaa atatagtggc
    23041 tccttattgc agtattcatt ttcggaagcg ggtcaagcta aagggtatag acgtttaaca
    23101 attaatgatg gcattattaa cgatgtattt attcctctta agccacttag acaattggaa
    23161 attatctcag gcgaatataa tgatgttatt aatgaaaaag ttcatgtgaa aaataaagat
    23221 aattatttac attttaaact taaaaatatg tctcatatta ctgatccaat gatgagttta
    23281 aaacaaattt atcctaatac tttagcgctg acgaatgaaa cttttaatta taatgaagaa
    23341 aataatgcta tagaaataag tgaaaaagat gacatgtcaa ttatcgaaat gttttataaa
    23401 catataactg ataaagaatt atcggatatc caatctaaaa agataaaaaa tattttagaa
    23461 aacgaattga gaaaggagga ttaatgaatg aaaccattac atttaaagtt gaataatttc
    23521 ggcccctttt taaaagaaga aattgatttt tctaaaattg ataataatga attgttttta
    23581 ataagtggta agactggatc gggtaaaaca atgatttttg atgcaatgac ttatgccttg
    23641 tttggtaaag catcaactga acaaagagaa gaaaatgatt tgagaagtca tttcgctgat
    23701 ggtaaacagc cgatgtcagt aacatttgaa tttcaattaa atcatcgaat ttataaagtg
    23761 catagacaag gcccttatat caaagaaggt aatacaacaa aaacgaacgc taaatttgat
    23821 gtatttgaga tggtggatgg caagtatgaa attagagaaa gtaaagtaat ttcaggtacc
    23881 caattcatta ttgaattatt aggagtaaat gcagatcaat tccgacaatt gtttattttg
    23941 cctcaaggtg aattcaaacg ctttttaata tcaaacagtc gtgaaaagca agggatatta
    24001 agaacactgt ttgacagtga aaaatttgaa gctatacgag aaatattaaa agaagaacta
    24061 aaaaaagaaa aagctcaaat cgagaataga tatcaacaaa ttgacctttt atggcaagaa
    24121 attgaatcat ttgatgatga caaaataaaa ggcttattag agcttgccac tcagcagata
    24181 gacaaattga ttgaaaatat accactttta caagctaggt cgaaagaaat actagcattt
    24241 gtaaatgaaa gtaaagaaac tgctattaaa gaatatgaaa taatagaaaa gaaaacacta
    24301 gaaaataata tattaaaaga taatattaac caactcaaca aaaataaaat tgatttcgtt
    24361 caattgaaag agcaacaacc tgaaatagac gaaattgaag ctaagttaaa gttgttacaa
    24421 gatattacca acctattgaa ttatattgaa aatagagaaa aaattgaaac taaaattgct
    24481 aatagcaaaa aagatatttc taaaaccaat aataaaatat tgaatcttga ttgtgataag
    24541 cgaaacatag acaaagagaa aaaaatgtta gaagaaaacg gagatttaat tgaaagtaaa
    24601 acctctttta ttgataaaac tagagtatta tttaacgata ttaataagta tcaacaaagt
    24661 tatctcaata ttgaatgctt gataactgag ggtgaacaat taggtgatga attaaataat
    24721 ctaattaaag gtttagaaaa ggtcgaagat tcaataggta ataacgaaag tgattacgag
    24781 aaaattatcg aactaaataa tgcgataact aacataaata atgaaattaa tataattaaa
    24841 gaaaatgaaa aagctaaagc tgaattagat aaactattag gtagtaagca agagttagag
    24901 aatcaaatta atgaagaaac aactataatg aagaatctcg aaataaaatt agatcactac
    24961 gataaatcaa aattggactt aaatgataaa gaaagcttta taagtgaaat taaatctgct
    25021 gtaaagattg gagatcaatg tccgatatgt ggtaatgaaa ttcaggattt agggcatcat
    25081 attgattttg acagtattgc taaacgtcaa aatgaaatta aagaaattga agcaaatatc
    25141 cacgcaataa aatcgaatat tgctgtgcat aattctgaaa ttaaatttgt taatgaaaaa
    25201 atatcgaata ttaatattaa aacgcaaagt gatttttcac tcgaagtatt gaataagcgt
    25261 ctgctagaaa atgaaaatgc attgaataat caaagagatc ttaataaatt tatagaacaa
    25321 atgaaagaag aaaaagataa tctaacgttg caaattcata ataaacaatt gcgtctaaat
    25381 aaaaatgaat ctgagttgaa attatgtcga gatctcatca ctgaatttga aacactctcg
    25441 aaatataata atatcactaa ttttgaggtg gattataaga agtatgttca agatgtgaat
    25501 cagcatcaag aactctcaaa ggagattgaa gataagttaa tgcaattgtc tcaaagaaag
    25561 ttaattgagc aaaataatct aaatcactat gaaaatcaac tagaaactta caataatgac
    25621 ttagaattga atgaacaatc tattgaaatg gaaatgtcga ggctgaattt aactgacgac
    25681 aatgatataa atgaaataat agcctggagg ggcgagcaag aggaattaga gcagaaaagg
    25741 gatacttata aaaaacgtta tcatgaattt gaaatggaaa tagctaggtt agaatcatta
    25801 accaaggata aagagttatt ggactctgat aaattaaaag atgaatatga gcaaaaaaaa
    25861 gaaaagatga atacactgat agatgaatac tctgctgttc attatcaatg tcaaaataat
    25921 attaataaaa cacaatctat agtttcgcat attaattact taaatcaaga attaaaggat
    25981 caacaagaaa tttttcaatt ggctgaaatt gtcagtggta agaataacaa aaatcttaca
    26041 ttggaaaact ttgtcttaat ttactattta gatcaaatta ttgcccaagc aaatctgaga
    26101 ttagcaacaa tgtcagataa tcgataccaa ctaattaggc gagaagcggt ttctcatggt
    26161 cttagtggcc tagaaattga tgtatttgat ttgcattcaa ataagtctag acatattagc
    26221 tcgttatcag gtggagaaac tttccaatcg tcgcttgcat tagctttagg gttaagcgaa
    26281 attgtacagc agcaatcagg aggtatttca ctagaatcaa tatttattga tgaaggattc
    26341 ggtacattag atcaagaaac gcttgaaaca gcgttagaca ctttattaaa tcttaaatca
    26401 actggtagaa tggttgggat tatttcacat gtgagcgaat tgaaaaatag aataccttta
    26461 gttttagaag tgaaatcaga tcaatatcag agttcaacaa gattcaaaag aaattaaaac
    26521 ataaaaaata gagatggtac tttggaatgt atagaacaac cttagcccat ctctttttat
    26581 ttaaaaatta ttttttctca cgcaataaat ctctgatttc agttaataac acaacatttt
    26641 cttccacaac tgcttcttct tcggcttctt ctttcttcat taatgtattt gcaatcttaa
    26701 caaagatgaa taaagcaaac gcgatgataa taaagtcgat aacagattgg ataaataaac
    26761 cgtatttaat accccagaat gaccattctt tagcaaaatc aactgatccg aaaattttac
    26821 caattaatgg catgatgata ttttctacta atgaagatat aatcttgttg aaagctgcac
    26881 ccatcacaac agcaattgct aaatctaaga cgttaccttt taaggcgaac tctttgaatt
    26941 cttttaacat tacactcaac ctctcttttt taaatgtaac ctcaattata caacaaataa
    27001 aaaaattaga aaatagatta ttcaagaaaa tttgattatc gcaaagacct ttgttatcct
    27061 ataaaggtgc gtgagttatt gaataaaatg tttagataat ctttttattc tactacataa
    27121 aattaaatat agaattgaag ggagtaatta attatgaatt cttcttcacc agagaatcca
    27181 aatggaaaga agtattcacc agtcttcatc tatagtgcaa ttgttgttgc tatagtcgta
    27241 ttacttggtg catttttacc tgaacaattc aactatgtta ccaataatat taaaatgtgg
    27301 attacagaaa agttaggttg gtattatctt attcttacta cgattatcgt gttcttctgt
    27361 atattcctta tttttagtcc tattggaaaa cttaaactag gtaaaccaaa tgacaaacct
    27421 gagtttaata caatttcatg gtttgctatg ttgtttagtg ctggtatggg gataggtttg
    27481 gtgttttatg gtgcagctga accgatggcg cactttgcta cgccacctac agcagatccc
    27541 aaaactactg aagcttatac tgaagctcta cgttcaacat ttttccattg gggattccat
    27601 gcttgggctg tttatggtgt tgttgcgtta gcgttggcat attcgcaatt ccgtaaaggt
    27661 gaaccaggtt tattatctag aactttacgt cctcttttag gtgataaagt agaaggtcct
    27721 attgggattt ttattgacgt tttatctgta tttgcgacaa tcgttggggt agccgtttcg
    27781 ttaggtatgg gtgctctaca aattaatggt ggtttacatt acttgttcaa tgttccaaac
    27841 aatacgtttg tacaagcgat tatcatcatt gttgttacta tcttatttat agcaagtgca
    27901 tggtctggat taagtaaagg tattcaatac ttaagtaact tgaacattgg tttaggtact
    27961 attttaatgg tagctgcttt aattgttgga ccaactgttc ttattttaaa tatgttaact
    28021 agctctacgg gtagtttact aaacacattc ttgtttaata gttttgatac agctgcttta
    28081 aatcctcaaa aacgtgaatg gatgtcttca tggacacttt attactgggg ttggtggtta
    28141 agttggagcc cattcgttgg agtgtttatt gcacgagttt caaaaggacg ttcaattaga
    28201 gagttcattt ctggtgtctt gctagttcca gcaattgtta gttttgtttg gtttagtgtc
    28261 tttggtgtat taggcatcga gacaggtaag aaacacaaag aaatttttga tatgactcct
    28321 gaaacacagc tatttggagt gtttaatcat gtgccatttg gcatagtttt atcgttgatt
    28381 gcattattat taattgcatc attctttatt acatctgctg actcagcaac atttgtatta
    28441 ggaatgcaaa caacatttgg ttcattaaat ccatctagta tggtaaaagt tgtttgggga
    28501 atttcacagg ccttaatagc atttgtactt ttattagctg gtggcggtaa tggcgctgaa
    28561 gctttaaatg cgattcaaag tgctgcaatt ataagtgcat tcccattctc ctttgtcgtc
    28621 atactcatga tggtaagttt ctacaaggat gcgaaccagg aacgtaaatt cctaggttta
    28681 acattgactc cgaataaaca tcgcttacaa gaatatatca agagtcaaca agaagattat
    28741 gaatctgaca ttcttgaaaa gcgtcagtca cgtagaaata tagagaaaaa agataactaa
    28801 taaaatttag ttaagtattt aaataacaag tagtatgtca ttctagtagc tagaacagat
    28861 atactacttg tttgtttttg tggaaaattg agtatattca aaaggataag aacgagaatt
    28921 tcgttattaa actacgaatt ctcgattttt ttatatttta agataggttt atttctgaca
    28981 acttaataga aagaggtttg acaaagctaa agtgaagtac gacggtataa aaaaattaac
    29041 tatactttta tagaaaatta actcagactg ggacatagat caatattcta tgctctacga
    29101 agttatattg gcagtagttg actgaacgaa aatgcgcttg taacaagctt ttttcaattc
    29161 tagtcagggg ccccaacaca gagaatttcg aaaagaaatt ctacaggcaa tgcgagttgg
    29221 ggtgagggcc ccaacacaga agctgacgaa aagtcagctt acaataatgt gcaagttggg
    29281 gatgggcccc aacaaagaga aattggattc ccaatttcta cagacaatgc aagttggcgg
    29341 ggccccaaca tagaagctgg cggaaagtca gtttacaata atgtgcaagt tggggtggga
    29401 cgacgaaata aattttgcga aaatatcatt tctgtcccac tcccatcaaa agaatgacat
    29461 tgaaaagaaa tattaaagtt tggcgccaca attttctttc tgctcaatga aataatacgt
    29521 ttgaaaattg aattgaatca ttcacgaaat tgataattat tctcaattaa taaaaaatac
    29581 ttattacacc ttacctgtat gataagtttt gcttatatac tctgattaaa aagtcaaaac
    29641 ctaaattaag cgttttctaa gcatgatgag ttgtttatca ataaatataa taatacaatt
    29701 taatcaaggc atataaatat aaaaatgtat caagggggat cattaaatgg ctgcaaattt
    29761 taaagagcaa tcaaaaaaac attttgactt gaatggccaa agttatactt actatgattt
    29821 aaaagctgta gaagagcaag gtattactaa agtttccaat ttaccttatt caattcgtgt
    29881 tttgttagaa tctttacttc gtcaagaaga tgattttgta attacagacg atcatattaa
    29941 agctttaagt cagtttggaa aagatggaaa tgaaggcgag gtaccattta aaccttctcg
    30001 tgttatttta caagatttca caggtgtacc agccgtagtt gatttagctt ctttacgtaa
    30061 agcaatggat gacgttgggg gagatattac taaaattaat ccagaagtac cggtggattt
    30121 agttattgac cactcagttc aagtggatag ctatgcaaat ccagaagctc ttgaacgtaa
    30181 tatgaaatta gaatttgaac gtaactatga acgttatcag tttttaaatt gggcaacgaa
    30241 agcatttgat aattacaatg cagttcctcc tgcaactgga atagttcacc aagttaactt
    30301 agaatattta gcaagtgttg tacatgttcg tgatgtagat ggtgaaaaaa ctgcatttcc
    30361 agatacatta gttggtactg attcacatac aacaatgata aatggtattg gcgtactagg
    30421 atggggtgtt ggtggtattg aagctgaagc tggaatgctt ggacaacctt cttatttccc
    30481 aattccagag gttattggtg tacgactagt aaattcatta ccacaaggcg caacagcaac
    30541 tgatttagcg ttaagagtaa ctcaagagct acgtaaaaaa ggtgttgttg gtaaatttgt
    30601 ggagttcttt ggtccaggtg tacaacattt accactagca gaccgtgcta caattgcaaa
    30661 catggcacca gagtatggag caacttgcgg attcttccca gttgatgatg aatctcttaa
    30721 atatatgaag ttaactggta gatcagacga acatatcgcg ctagtaaaag aatatttgaa
    30781 acaaaaccat atgttctttg atgttgagaa agaagatcct aattatacag atgttatcga
    30841 attggattta tcaacagttg aagcatcgct ttcaggacca aaacgtcctc aagatttaat
    30901 tttcttaagt gatatgaaat catcatttga aaattctgta acagctccag caggcaacca
    30961 aggacacggt ttagataaaa gtgaatttga taagaaagct gaaattaact ttaaagatgg
    31021 atcaaaagct acaatgaaaa caggtgatat tgcaatagca gcaattacat catgtacaaa
    31081 tacatctaac ccttatgtaa tgttaggtgc aggtttagtt gctaaaaaag cagttgaaaa
    31141 aggcttgaaa gttcctgaat acgttaaaac ttctctagca ccaggatcaa aagttgttac
    31201 cggatattta agagatgctg gcttacaacc ttatttagat gatttaggct tcaacttggt
    31261 tggttatgga tgtacaactt gtatcggtaa ttcaggtcct ttattaccag aaattgaaaa
    31321 agcgattgct gatgaggacc tattagtgac atctgtatta tctggtaacc gtaactttga
    31381 aggtcgtatc catcctcttg ttaaagccaa ttacctagct tcaccacagt tagttgttgc
    31441 ttatgcatta gctggaacgg ttgatattga tttacagaat gaacctattg gtaaaggtaa
    31501 tgacggtgaa gatgtatatt tgaaagatat ttggccatca attaaagaag tttcagatac
    31561 cgttgatagt gttgtaacac ctgaattatt tattgaagaa tataataacg tatacaataa
    31621 caacgaatta tggaatgaga ttgatgtaac tgatcaacct ctatatgact ttgatcctaa
    31681 ttcaacatac attcaaaatc catcattctt ccaaggatta tctaaagaac cgggtacgat
    31741 tgttccatta aatggtttac gtgttatggg taaattcggt gattctgtga caactgacca
    31801 catctctcca gcaggtgcaa ttggtaaaga tacgccagct ggtaaatatt tacaagatca
    31861 tcaagtgcct attcgtgaat ttaattcata tggttcaaga cgtggtaatc acgaagtaat
    31921 ggttcgaggt acgtttgcta atatacgtat taaaaaccaa ttagcgccag gtactgaagg
    31981 tggttttaca acttattggc caacaaatga agtaatgcct atctttgatg ctgcaatgaa
    32041 atataaagaa gatggtacag gtttagttgt attagctggt aacgattatg gtatgggttc
    32101 atctcgtgac tgggcagcaa aaggtacaaa cttattaggt gttaaaacag ttattgcaca
    32161 aagttatgaa cgtatccatc gttcaaattt agttatgatg ggtgtattac cattagagtt
    32221 taaaaaaggt gaatcagctg attctcttgg tctagatggt acagaagaaa tttctgttaa
    32281 tattgatgaa aatgttcaac cacatgacta cgtcaaagtt actgctaaga agcaagatgg
    32341 tgatttggta gaatttgacg ctatggttcg ttttgactca cttgttgaaa tggattacta
    32401 tcgtcacggt ggaattttac aaatggtttt aagaaataaa ttagcgcaat aaaaaataga
    32461 tatcacagta aaatttcaat cggtatttga ggcactttga tagtgctcaa aaatacttct
    32521 ataaacttta tgatataata ggtcggttca aaacctttgt gttcttggcc ggcctcttct
    32581 tgtattttat gttagaatga gatataaagt taaactgaaa gaaggcttaa aatgatatat
    32641 agtattacag aaatagaagc gcgttatgct gaaactgata agatgggtgt aatttatcac
    32701 gggaattatg caacttggtt tgaagttgcg cggttggatt atatatcgaa gttaggtttt
    32761 agttatgctg atatggaaaa acaaggaatc atttcacctg tgactgacct caatgtcaat
    32821 tataaaaagt ctatttttta tccagaaaaa gttaaagtta aaacttgggt tgaaaaatat
    32881 tcgagattac gttcagtgta taaatatgag atttttaatg aaaaaggtga acttgcaact
    32941 acaggttcca cagaattgat ttgcattaaa gaagatactt ttaagcctat acggttggat
    33001 cgttatttcc cagattggca tgaagcttat agtaaagtgc aaacgctcaa taatgaaggg
    33061 aaaacagtag agataatgga tggtattgat tctttataag ttactgtaaa tgtttggaga
    33121 ggcaatatta acaattaatc tataagaaat agccaatacg ttaacattaa tgtaattagc
    33181 gtgaagataa gctaatatat agcaaaaacg aacttgttca tacaacatca gatgtgctaa
    33241 accaaagtac aacttccgag gttcaggaca catcagaatg tgtaaacaag ttcgttttat
    33301 tttagttatt ttgtggaata agaaatttca tcttcgtgat caactacatt tacaataatg
    33361 tggtcatctt caaagtacca caaatctttt tccgctacga caacatttaa atcgtcatat
    33421 tgttgttcat agccaatatc aacatcttcc tttggttcaa ctgtaaaagc aggactaaat
    33481 ccttgcttga gttggaattc gccaccatat cttacaaaaa acacgagcac tttattattt
    33541 tcaggcaact caagttcatt tttaaaccaa gttactgctg catcagtaag ttctatttgc
    33601 ataacaatga cctcctatat ttattacaga atgggagtgg gccaacttgt attatttgtg
    33661 gaatttctta tcgaaattct ctgtgttgga gcccacccca acctgctcat tattgtaagc
    33721 tgaatttcca taagcttcta tgttgggacc cccgaccaga attgaaaaaa cctagttata
    33781 agcgcatttc gttcggttaa ctacagctaa tataacattg tgaagcctat gacattgatt
    33841 tatgtctcgg tctcaaatgt tcttgtaaaa aaactaagta tagttgagtt ttaagttaaa
    33901 aaaattgttt ttgcaaaaat aaaataatcc atcaactgca aaaaaatatg caatgatgga
    33961 ctaatgtcaa aaaattgtta catccatttt attttaggtt cttcgcctct aaaaatcctt
    34021 gcgatattag agcgatgtct aattatcaat atgattgaaa ctaagaaact aacgactaat
    34081 aaaatatagt cttgaatgat aagcgagcca atcacacagc aaattgctgc aacgatactt
    34141 gctaaagaaa catatttaaa aatcttcaat acaataaaga agataattgc aagtattagt
    34201 aaaagtatcg gattgactcc caagacgaca cctgcactag ttgcaacagc tttgccacct
    34261 tggaatttta aataaacagg ataaacgtgt ccaagtatag cgaataagcc aacaattaaa
    34321 ccatttgtaa aaaaagtact aatagggcca tctgcgtgaa ctggtaacca taaagggaag
    34381 aaaacagtta tgaacccttt gaaaatatct agaaatgtta ccaagaatcc tgcaggacga
    34441 cctaatactc taaagctatt agtagcgcca gtattaccac taccaaattg tctaatatct
    34501 tttttgaaaa ataattttcc aattacgaat ccacttggga aagcgccgat aagataactt
    34561 agtagtaaca tgacgattat catcataaat attacacatc ctttaatatc ttaggactat
    34621 tttatcatat tcatttaaat tacggctaaa aattttaaaa acggggatta atatatggaa
    34681 ttaagctatg aaagttaatt gatacttgca ttttacgctg atttatataa gaataactat
    34741 tgtatagttt taaaaacgaa cgtacgtttg caggaggcga aatcattggc aatgaataaa
    34801 caaaataatt attcagatga ttcaatacag gttttagagg ggttagaagc agttcgtaaa
    34861 agacctggta tgtatattgg atcaactgat aaacggggat tacatcatct agtatatgaa
    34921 attgtcgata actccgtcga tgaagtattg aatggttacg gtaacgaaat agatgtaaca
    34981 attaataaag atggtagtat ttctatagaa gataatggac gtggtatgcc aacaggtata
    35041 cataaatcag gtaaaccgac agtcgaagtt atctttactg ttttacatgc aggaggtaaa
    35101 tttggacaag gcggctataa aacttcaggt ggtcttcacg gtgttggtgc ttcagttgta
    35161 aatgcattga gtgaatggct tgaagttgaa atccatcgag atggtagtat atatcatcaa
    35221 agttttaaaa acggtggttc gccatcttct ggtttagtga aaaaaggtaa aactaagaaa
    35281 acaggtacca aagtaacatt taaacctgat gacacaattt ttaaagcatc tacatcattt
    35341 aattttgatg ttttaagcga acgactacaa gagtctgcgt tcttattgaa aaatttaaaa
    35401 ataacgctta atgatttacg cagtggtaaa gagcgtcaag agcattacca ttatgaagaa
    35461 ggaatcaaag agtttgttag ttatgtcaat gaaggaaaag aagttttgca tgacgtggct
    35521 acattttcag gtgaagcaaa tggtatagag gtagacgtag ctttccaata taatgatcaa
    35581 tattcagaaa gtattttaag ttttgtaaat aatgtacgta ctaaagatgg tggtacacat
    35641 gaagttggtt ttaaaacagc aatgacacgt gtatttaatg attatgcacg tcgtattaat
    35701 gaacttaaaa caaaagataa aaacttagat ggtaatgata ttcgtgaagg tttaacagct
    35761 gttgtgtctg ttcgtattcc agaagaatta ttacaatttg aaggacaaac gaaatctaaa
    35821 ttgggtactt ctgaagctag aagtgctgtt gattcagttg ttgcagacaa attgccattc
    35881 tatttagaag aaaaaggaca attgtctaaa tcacttgtga aaaaagcgat taaagcacaa
    35941 caagcaaggg aagctgcacg taaagctcgt gaagatgctc gttcaggtaa gaaaaacaag
    36001 cgtaaagaca ctttgctatc tggtaaatta acacctgcac aaagtaaaaa cactgaaaaa
    36061 aatgaattgt atttagtcga aggtgattct gcgggaggtt cagcaaaact tggacgagac
    36121 cgcaaattcc aagcgatatt accattacgt ggtaaggtaa ttaatacaga gaaagcacgt
    36181 ctagaagata tttttaaaaa tgaagaaatt aatacaatta tccacacaat cggggcaggc
    36241 gttggtactg actttaaaat tgaagatagt aattataatc gtgtaattat tatgactgat
    36301 gctgatactg atggtgcgca tattcaagtg ctattgttaa cattcttctt caaatatatg
    36361 aaaccgcttg ttcaagcagg tcgtgtattt attgctttac ctccacttta taaattggaa
    36421 aaaggtaaag gcaaaacaaa gcgagttgaa tacgcttgga cagacgaaga gcttaataaa
    36481 ttgcaaaaag aacttggtaa aggcttcacg ttacaacgtt acaaaggttt gggtgagatg
    36541 aaccctgaac aattatggga aacgacgatg aacccagaaa cacgaacttt aattcgtgta
    36601 caagttgaag atgaagtgcg ttcatctaaa cgtgtaacaa cattaatggg tgacaaagta
    36661 caacctagac gtgaatggat tgaaaagcat gttgagtttg gtatgcaaga ggaccaaagt
    36721 attttagata attctgaagt acaagtgctt gaaaatgatc aatttgatga ggaggaaatc
    36781 tagtgagtga aataattcaa gatttatcac ttgaagatgt tttaggtgat cgctttggaa
    36841 gatatagtaa atatattatt caagagcgtg cattgccaga tgttcgtgat ggtttaaaac
    36901 cagtacaacg tcgtatttta tatgcaatgt attcaagtgg taatacacac gataaaaatt
    36961 tccgtaaaag tgcgaaaaca gtcggtgatg ttattggtca atatcatcca catggagact
    37021 tctcagtgta cggagcaatg gtccgtttaa gtcaagactg gaagttacga catgtcttaa
    37081 tagaaatgca tggtaataat ggtagtatcg ataatgatcc gccagcggca atgcgttaca
    37141 ctgaagctaa gttaagctta ctagctgaag agttattacg tgatattaat aaagagacag
    37201 tttctttcat tccaaactat gatgatacga cactcgaacc aatggtattg ccatcaagat
    37261 ttcctaactt actagtgaat ggttctacag gtatatctgc aggttacgcg acagatatac
    37321 caccacataa tttagctgaa gtgattcaag caacacttaa atatattgat aatccggata
    37381 ttacagtcaa tcaattaatg aaatatatta aaggtcctga ttttccaact ggtggtatta
    37441 ttcaaggtat tgatggtatt aaaaaagctt atgaatcagg taaaggtaga attatagttc
    37501 gttctaaagt tgaagaagaa actttacgca atggacgtaa acagttaatt attactgaaa
    37561 ttccatatga agtgaacaaa agtagcttag taaaacgtat cgatgaatta cgtgctgaca
    37621 aaaaagtcga tggtatcgtt gaagtacgtg atgaaactga tagaactggt ttacgaatag
    37681 caattgaatt gaaaaaagat gtgaacagtg aatcaatcaa aaattatctt tataaaaact
    37741 ctgatttaca gatttcatat aatttcaaca tggtcgctat tagtgatggt cgtccaaaat
    37801 tgatgggtat tcgtcaaatt atagatagtt atttgaatca tcaaattgag gttgttgcaa
    37861 atagaacgaa gtttgaatta gataatgctg aaaaacgtat gcatatcgtt gaaggtttga
    37921 ttaaagcgtt gtcaatttta gataaagtaa ttgaattgat tcgtagctct aaaaacaagc
    37981 gtgacgctaa agaaaacctt atcgaagtat tcgagttcac agaagaacag gctgaagcaa
    38041 ttgtaatgtt acagttatat cgtttaacaa acactgacat agttgcgctt gaaggtgaac
    38101 ataaagaact tgaagcatta atcaaacaat tacgtcatat tcttgataac catgatgcat
    38161 tattgaatgt cataaaagaa gaattgaatg aaattaaaaa gaaattcaaa tctgaacgac
    38221 tgtctttaat tgaagcagaa attgaagaaa ttaaaattga caaagaagtt atggtgccta
    38281 gtgaagaagt tattttaagt atgacacgtc atggatatat taaacgtact tctattcgta
    38341 gctttaatgc tagcggtgtt gaggatattg gtttaaaaga tggtgacagt ttacttaaac
    38401 atcaagaagt aaatacgcaa gataccgtac tagtatttac aaataaaggt cgttatctat
    38461 ttataccggt tcataaatta gcagatattc gttggaaaga attggggcaa catgtatcac
    38521 aaatagttcc tatcgaagaa gatgaagtgg ttattaatgt ctttaatgaa aaggacttta
    38581 atacagatgc attttatgtt tttgcgactc aaaatggcat gattaagaaa agtacagtgc
    38641 ctctatttaa aacaacgcgt tttaataaac ctttaattgc tactaaagtt aaagaaaatg
    38701 atgatttgat tagtgttatg cgctttgaaa aagatcaatt aattaccgtc attactaata
    38761 aaggtatgtc attaacgtat aatacaagtg aactatcaga taccggatta agggcagctg
    38821 gtgttaaatc aataaatctt aaagctgaag atttcgttgt tatgacagaa ggtgtttctg
    38881 aaaatgatac tatattgatg gccacacaac gcggctcgtt aaaacgtatt agttttaaaa
    38941 tcttacaagt tgctaaaaga gcacaacgtg gaataacttt attaaaagaa ttaaagaaaa
    39001 atccacatcg tattgtagct gcacatgtag tgacaggtga acatagtcaa tatacattat
    39061 attcaaaatc aaatgaagaa catggtttaa ttaatgatat tcataaatct gaacaatata
    39121 caaatggctc attcattgta gatacagatg attttggtga agtaatagac atgtatatta
    39181 gctaaaaact atatgcaatc acgaaattaa atgataaaat acagtaatgt taaattttga
    39241 ctaaattcaa gggatttata ttaaatgctg accaagtact tatcgttaaa ttagcgatag
    39301 actttgacca aactaatata aatctcttgt attgtataag aaatgatgat gtatctctat
    39361 atttactgaa gtttcaattc ggtctaattt tatagaaggt gcatgattca tgtagaggat
    39421 gcgaggggtt tattttgaaa gatttcgata gtttaattcc tggatggttt aaagaatttg
    39481 tccatgttgg taccgattta atatggtctc aatatttaat tggtctatta ttgacagctg
    39541 gattcttctt tacaattagt tctaaattcg ttcaattacg aatgttacct gaaatgttta
    39601 gagctttagt agaacgtcca gaaactttag aagatggtaa gaagggtatt tcgccattcc
    39661 aagcatttgc gattagtgct ggttcgagag ttggtactgg taatattgct ggtgttgcga
    39721 ctgcgattgt tttaggcggt ccaggtgcag tgttttggat gtgggttatt gcatttatag
    39781 gtgcagcgag tgcatttata gaagcgactt tggctcaggt ttataaagta catgataaag
    39841 atggtggatt ccgtggtggt ccagcttact atattactaa aggtttaaat caaaaatggc
    39901 taggtatcgt atttgcgatt ttaattacaa ttacatttgc atttgtattt aacacagtgc
    39961 aatctaatac aattgcggag tcgttaaata cgcaatataa tattagtcca gtaatcacag
    40021 gtattatttt agcaatcgta acagctatta ttatatttgg tggtgtacgt agtattgcta
    40081 cgttatcttc gttaattgta ccgattatgg ctatcattta cattggtatg gttttagtaa
    40141 tattgctatt taatttagat caaattgttc ctatgatagg tacgattatt aaaagtgcat
    40201 ttggtatcga acaagtaact ggtggcgctg taggtgctgc ggttcttcaa ggtatcaaac
    40261 gtggtttatt ctctaacgaa gctggtatgg gttctgcgcc gaatgcagcg gcaactgctg
    40321 ccgtaccaca ccctgttaag caaggtttaa tccaatcatt aggtgtgttc tttgatacaa
    40381 tgttggtttg tacagcaact gcaatcatga ttttactata ttcaggattg aaatttggtg
    40441 ataacgcacc tcaaggtgtt gcagttactc aatcagcact taatgagcat ttaggttctg
    40501 ctggaggtat tttcttaaca atagcagtta cactgtttgc attttcatct gttgtaggta
    40561 attactatta cggtcaatct aatattgaat ttttatcaac aaatcgtgtg atattattta
    40621 tctttagatg tcttgttgta gtacttgtct ttgtcggtgc agttgtaaaa acagaaacag
    40681 tatggaatac ggcagactta tttatgggct taatggcaat tgtaaacatt atttccatta
    40741 taggactgtc caatgtagct tttgcattga tgaaagatta tcaaaagcag aaaaaagaag
    40801 gcaagaaccc tgtctttaaa cctgaaaact tagaaattaa cttatttgga attagtgctt
    40861 ggggcgctaa caaatataag aactctgata aataaatatt tttaatgtaa cgattcatta
    40921 tataaaaatc aaataaaccc tgaggttttc aaattaaagc gaaaatctca gggttttaaa
    40981 tttgtactca ataatcatct gtatcattac actagttaat ctaagatttg attatatatt
    41041 aatatagtaa ggttgagatt tatttcctcc attggtgtgc aaagactata ccatttataa
    41101 gacatattgt tggatagatg aatataaatt tattttagtt ttgcacaatt taatagtgcg
    41161 ttttagtttg tattgagtat taattcagat aatatataaa taaatagaat tatttgtaaa
    41221 tatgggagtc agattttttt attatagtta ttccactttg agagacatcg aaattaaatt
    41281 aagatatatc atataggata ggcgtgtaa
//
LOCUS       DAPDIM010000019        38866 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000019 DAPDIM010000000
VERSION     DAPDIM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 38866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38866
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.019"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..1443
                     /locus_tag="RFE25_001065"
     CDS             <1..1443
                     /locus_tag="RFE25_001065"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019142.1,HMM:NF028351.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="E domain-containing protein"
                     /protein_id="HDU2816153.1"
                     /translation="PYETKRVLDPTMEPGSPDKVAQKGENGEKTTTTPTTINPLTGEK
                     VGEGEPTTEVTKEPIDEIVNYAPEIIPHGTREEIDPNLPEGETKVIPGKDGLKDPETG
                     EIIEEPQDEVIIHGAKDDSDADSDSDSDSDSDADSDSDADSDSDADSDSDSDADSDSD
                     SDSDSDADSDSDSDSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDADSD
                     SDADSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDSDADSDSDSDSDSDSDSDSD
                     SDSDSDSDSDSDADSDSDADSDSDADSDSDADSDSDADSDSDSDSDSDSDADSDSDAD
                     SDSDADSDSDADSDSDSDSDSDADSDSDSDADSDSDSDSDSDADSDSDADSDSDADSD
                     SDADSDSDSDSDSDSDSDSDADSDSDADSDSDADRDHNDKTDKPNNKELPDTGNDAQN
                     NGTLFGSLFAALGGLFLVGRRRKNKNNEEK"
     gene            1567..3183
                     /locus_tag="RFE25_001066"
     CDS             1567..3183
                     /locus_tag="RFE25_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002448877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly(glycerol-phosphate)
                     alpha-glucosyltransferase"
                     /protein_id="HDU2816154.1"
                     /translation="MEFEHKLEKLISEVNNKTEINNYVFFSLGKSSVKAQVKLLKKTN
                     YLKQDISKLALKFKKKSGEFPEWIKLDIVTSTEKILFKELKKTLINTRRNYVDFGIAF
                     DSQWNFAVLPEEINANAFVRPDNTTKELFLSEKNINNYLRKYTTNKKAFSSEFYNEKE
                     VIKFYTQGFFIGDEEVHELYSEGYKKGLRKVNDLNNEIDQLIESSTNFLQNMLLDNGK
                     YIYGYFPHFDNEIGFYNVLRHSSSTYALIEGLSYLGKSLQPVEKAIDYIILNQLFEIG
                     DKAYIFDDTEEANEIKLGQNASFIFAVCEYLKHEDNPKFLESAQKVAKGILSMIDEDT
                     YETTHLLNYPDLSVKEKFRIIYYDGEAALALLRLYQKDENELWLKTVENLMDRFIEKK
                     YWQYHDHWLGYCTNELVQINPQDKYFEFGIKNVNNYLDYIKNRETTFPTFLEMLMATY
                     RLVQKAKDTGREELVNNLIDEQYLIDVINIRADYQRVGFFYPEIAMYFKNPSRILGSF
                     FIKHHGYRVRIDDIEHYLSGYVQYQLAFNR"
     gene            complement(3343..4854)
                     /locus_tag="RFE25_001067"
     CDS             complement(3343..4854)
                     /locus_tag="RFE25_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDU2816155.1"
                     /translation="MIYSVGNRLGNKLTGIEKAMINRHNLFKNHSITSKLIFASWSPR
                     LHFNASLFQIEDDDILSLYDVLQDSINIKSIHKDWITHWTKECNYTLKFIENTNDIKI
                     YEKSNYRMYVHFNDSNYQHLDYINHFDVNQRKIRRDLYDSRGFLSCSRTLTTNQKVVC
                     EHYYTPEGTIKFQKFFNPELENSQSQLIIYNTDSQLKYFNNDQELLAFAIEKLYKNGD
                     IFLSDKNINTAPIFNNTSETIPVLAVLHSTHVKNIDMVYESDIKNTYKHVFNNLNRYS
                     GIIVSTKQQQLDISARINNEIPVHTIPVGYIDEHFTNLKRNNHSINNNKIISVARYSP
                     EKQLNHQIELVSKLIKEFPNIQLHLYGFGKEEEKYKQLITEYNLENNVFLRGFRRNLS
                     AEIQDAYMSLITSNMEGFNLGLLETITEGIPPVGYNSKYGPSELILNNENGYLINKND
                     KDELYNRVRNLLLDKTLRDTFSQECIKHSKAFSSKIVMKLWEDRFSTINSSYE"
     gene            complement(4877..6557)
                     /locus_tag="RFE25_001068"
                     /pseudo
     CDS             complement(4877..6557)
                     /locus_tag="RFE25_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001621813.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate ligase"
     gene            complement(7894..8028)
                     /locus_tag="RFE25_001069"
     CDS             complement(7894..8028)
                     /locus_tag="RFE25_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816156.1"
                     /translation="MKLHWYIYYFLSISVILFMIIYHYLATSMTVDYEITVSIAKLLL
                     "
     gene            7992..8084
                     /locus_tag="RFE25_001070"
     CDS             7992..8084
                     /locus_tag="RFE25_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816157.1"
                     /translation="MTKNSKYTNEVSKEQFQEIENVNNKVKEFY"
     gene            8231..9975
                     /locus_tag="RFE25_001071"
                     /pseudo
     CDS             8231..9975
                     /locus_tag="RFE25_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04141 family sporadically distributed
                     protein"
     gene            complement(10073..10428)
                     /locus_tag="RFE25_001072"
                     /pseudo
     CDS             complement(10073..10428)
                     /locus_tag="RFE25_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662030.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
     gene            complement(10733..10821)
                     /locus_tag="RFE25_001073"
                     /pseudo
     CDS             complement(10733..10821)
                     /locus_tag="RFE25_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10919..11674)
                     /locus_tag="RFE25_001074"
     CDS             complement(10919..11674)
                     /locus_tag="RFE25_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDU2816158.1"
                     /translation="MDIVNIVIMLLIGVFGGFISGLVGVGGAIIIYPAILLLPPLFGA
                     PAYSAYIASGLTSSQVFFSTLSGSLKARKKTEFSPQLVLYMGGGMIIGSMLGAFLANL
                     FDATFVNTVYIIIALLALTLMFIKVKPSSEKSSFNKYLLVIIGLFIGIISGIVGAGGA
                     FIIIPILLVLFKLPMNTVVANSIVIAFISSIGAFVIKLIQGYIPLYDALFLIIGSIIF
                     APIGLKLSKKVPNIIQKWIISILIVFAIVQLIL"
     gene            complement(11674..11934)
                     /gene="cstR"
                     /locus_tag="RFE25_001075"
     CDS             complement(11674..11934)
                     /gene="cstR"
                     /locus_tag="RFE25_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="persulfide-sensing transcriptional repressor
                     CstR"
                     /protein_id="HDU2816159.1"
                     /translation="MNYDKKMINRINRIQGQLNGIIKMMEEGKDCKDVITQISASKSS
                     LQRLMGIIISENLIECVKVAADDEESSQELINEAVNLLVKSK"
     gene            12071..13135
                     /gene="cstA"
                     /locus_tag="RFE25_001076"
     CDS             12071..13135
                     /gene="cstA"
                     /locus_tag="RFE25_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="persulfide response sulfurtransferase CstA"
                     /protein_id="HDU2816160.1"
                     /translation="MKQYGEKFIDEFSKAELEKLAKQGQLIDVRTEEEYALGHINGSI
                     LHPVDEIESFNKEKNKTYYVICRSGNRSANASKYLAKQGYNVINLDGGYKAYEENDSY
                     DTQEEYKSIEIKADRKQFNYRGFQCPGPIVKISQEMKNIEVGDQIEVKVTDPGFPSDI
                     KSWVKQTRHTLVKLDENNNGINAIIQKEKAKDLDINYSAKGTTIVLFSGELDKAVAAL
                     IIANGARAAGKDVTIFFTFWGLNALKKVQTVNVKKQGIAKMFDLMLPQKNIRMPLSKM
                     NMFGLGNMMMRYVMKKKNVDSLPTLINQAIEQNIKLIACTMSMDVMGIQKEELRDEVE
                     YGGVGTYIGATENANHNLFI"
     gene            13166..14500
                     /gene="cstB"
                     /locus_tag="RFE25_001077"
     CDS             13166..14500
                     /gene="cstB"
                     /locus_tag="RFE25_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="persulfide dioxygenase-sulfurtransferase CstB"
                     /protein_id="HDU2816161.1"
                     /translation="MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADS
                     EGLTITQATETHIHADFASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGD
                     IIQVGNVKLEVLHTPGHTPESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEK
                     SVQIKGSTEISAKQMYESVQNIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKI
                     NNWAFNEIDETKFIESLTSNQPAPPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAF
                     DLRSKEAFHGGHTKGTINIPYNKNFINQIGWYLDFEKDIDLIGDKSTVEKAKHTLQLI
                     GFDKVAGYRLPKSGISTQSVHSADMTGKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLL
                     NENIPFNKEDKIYVHCQSGVRSSIAVGILESKGFENVVNIREGYQDFPESLK"
     gene            14519..15712
                     /gene="sqr"
                     /locus_tag="RFE25_001078"
     CDS             14519..15712
                     /gene="sqr"
                     /locus_tag="RFE25_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II sulfide:quinone oxidoreductase Sqr"
                     /protein_id="HDU2816162.1"
                     /translation="MNKHYQIVIIGGGTAGVTVASRLLRKNQNLKEKIAIIDPADHHY
                     YQPLWTLVGAGVSSLKSSRKDMESVIPEGANWIKQAVSSFQPENNSVILGDNTVVYYD
                     FLVVAPGLQINWSSIKGLKENIGKNGVCSNYSPDYVNETWNQISNFKQGNAIFTHPNT
                     PIKCGGAPMKIMYLAEDYFRKHKIRSNANVIYATPKDALFDVGKYNKELERIVEERNI
                     TVNYNYNLVEIDGDKKVATFEHIKAYDRKTISYDMLHVTPPMGPLDVVKESTLSDSEG
                     WVDVNPTTLQHKSYSNVFALGDASNVPTSKTGAAIRKQAPIVANNLLQVMNNQMLTHH
                     YDGYTSCPIVTGYNRLILAEFDYNKNTKETMPFNQAKERRSMYIFKKDLLPKMYWYGM
                     LKGLI"
     gene            complement(16379..17365)
                     /locus_tag="RFE25_001079"
     CDS             complement(16379..17365)
                     /locus_tag="RFE25_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HDU2816163.1"
                     /translation="MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEF
                     TNTESFCHPEGIHSVRGRLTFSEDEHPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLN
                     MGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKH
                     VFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGL
                     ELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQF
                     KSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL"
     gene            17674..17877
                     /locus_tag="RFE25_001080"
     CDS             17674..17877
                     /locus_tag="RFE25_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816164.1"
                     /translation="MEDLKESLKSLGWWDLFFAIPMFLLFAYLPNYNFITIFLNIVII
                     IFFSIGLILTTHIIIDKIKSNTK"
     gene            17926..18222
                     /locus_tag="RFE25_001081"
     CDS             17926..18222
                     /locus_tag="RFE25_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
                     /protein_id="HDU2816165.1"
                     /translation="MATKKDVHDLFLNHVNSNAVKTRKMMGEYIIYYDSVVIGGLYDN
                     RLLVKATKSVRHQLQDNTLVSPYPGAKEMILIPDITEAINLTNLFELIKNDLKN"
     gene            18430..19032
                     /locus_tag="RFE25_001082"
     CDS             18430..19032
                     /locus_tag="RFE25_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816166.1"
                     /translation="MLISLVIPVFALLVIGGIIWVIIEGIVHISKKNKAIDNFLNQVN
                     KVSETYKFATAFLFLILATAGISQFYLYYIVSAFLFWLVILTFGIAGIIFLMPYGLCF
                     LPLYKQKKKKQTFKKYMVYTTIGLSICLGLSLVLVHTTKIYMDEGGVRYYYGSFVMKQ
                     AGGYAYLALAVLSTLLIVAKKATNKNKEIETVDNTNITER"
     gene            19299..22451
                     /locus_tag="RFE25_001083"
     CDS             19299..22451
                     /locus_tag="RFE25_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA2/NAM7 family helicase"
                     /protein_id="HDU2816167.1"
                     /translation="MSQLLNDTLSAWLLIESLSPGEVNFTAEDILSAEHFKNGAKQAQ
                     LQSFDEYFEIWNSERFIISEEKSETGELIFKFYRHCFRYNEINLKIQDIFDDYSDIHN
                     PNGTHCYGYTFNTDKHGKVIVDSIHIPMIMSALKEIEKNKNANIEEKFNDSVEKFFQK
                     VKEILADEPINEFKLKKMDKAYDEYFSVLNSKKDGLFGHYVAIEYVKDSDLPQPEFNS
                     FFISDIEKARKSPNQTLIDYIEGVEESQRIEVDENKEMFDKFLHPSRLPDGRWPSQTE
                     FRLSLMQQLAVNQITSGNERISSVNGPPGTGKTTLLKDIFAHLVVERGKELAKLNNPK
                     DAFVKTKIHETDDKYVYLLKESIAKYKMVVASSNNGAVENISKDLPKIEEIIRNPEKC
                     KFPKYEQNYANLAHELKDFAEIAEDLIGESAWGLFSGVFGKSTNINQVLSHMLKQDAN
                     DIGFAKLLQNENNRMSYNELMSEWQSHQRAFLEELRHVEMLKEESIRAYDVYKNCESF
                     SKIEQVINSEKTSIEEQVYHLDNETLRDNKEIEDLDNRINYIVKQIETLNELIKSIKE
                     SNKGFINKLKAMFNSEEDESYKDHNKEKQQLLTQQLELEKCKKNKHEDLVSKLKEKEK
                     LIKQLTKVQLQLDELNSQLQELEAYRIESKITIPEKDFWSDNNYDERQVTNLWTSDEL
                     QYRRAMLFLRAMILHKLLLIANNTTIYYAINDFKDRRKLIDANPDKVHNAWNVMHLIF
                     PVVSTTFASFKSMYGGIPKDFIDYLFIDEAGQAIPQAAVGALYRSKKVVAVGDPIQIE
                     PVVTLESHLIDNIRKNYHVPEYLVSKEASVQSVADNANQYGFWKSDATDSNQKTWIGI
                     PLWVHRRCLKPMFTIANQIAYNNKMVLPSNITKVGKTGWYDVKGNAVQKQFVKEHGEK
                     VVGLLADDWIEAIKEGKNEPSSFVISPFSAVQQQIKRMLKQQLPTRIDIERTKINQWV
                     DKSIGTVHTFQGKEAQKVYFVIGTDNTQDGAVNWSCEKPNLLNVAVTRAKKEFYVIGD
                     MQRIQMKPFYETIFKERNVK"
     gene            22508..22990
                     /locus_tag="RFE25_001084"
     CDS             22508..22990
                     /locus_tag="RFE25_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816168.1"
                     /translation="MEKFNNWILNAISGSQTDKNETTEELKGAKFIILYAYSMLVLLA
                     LVISNIFIHILEPKLSITTQIIIVLILIEALIGLRFLKAYDVKRGKDKENKKNSKDFV
                     KLKSILVAILFTSLALTAGTVADIYGFTDLGNTRSDLIVWSIGGIIFGLVCYTMEDKK
                     "
     gene            23196..24182
                     /locus_tag="RFE25_001085"
     CDS             23196..24182
                     /locus_tag="RFE25_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylinositol-specific phospholipase C"
                     /protein_id="HDU2816169.1"
                     /translation="MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDES
                     KHLTEINMPGSHDSGSFTLTDPVKSVWAKTQGKDYLTQMKSGVRFFDIRGRASADNMI
                     SVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYY
                     YNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFE
                     TKINNGSLNLKVQDEYKDYYDKKVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFN
                     STYNYASHINPEIAKTIKENGKARTGWLIVDYAGYPWPGYDDIVSEIIDSNK"
     gene            24403..25173
                     /locus_tag="RFE25_001086"
     CDS             24403..25173
                     /locus_tag="RFE25_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2816170.1"
                     /translation="MMKRLNKLVLGIIFLFLVISITAGCGIGKEAEVKKSFEKTLSMY
                     PIKNLEDLYDKEGYRDDQFDKNDKGTWIINSEMVIQPNNEDMVAKGMVLYMNRNTKTT
                     NGYYYVDVTKDEDEGKPHDNEKRYPVKMVDNKIIPTKEIKDKNIKKEIENFKFFVQYG
                     NFKDLSKYKDGDISYNPEVPSYSAKYQVTNDDYNVKQLRKRYDIPTNKAPKLLLKGTG
                     NLKGSSVGYKDIEFTFVEKKGENIYFSDSLHLEPSEDK"
     gene            25225..25995
                     /locus_tag="RFE25_001087"
     CDS             25225..25995
                     /locus_tag="RFE25_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2816171.1"
                     /translation="MIKRVNKLVLGISFLFLIISIFAGCGTGKEAEIKKSFEKTLSMY
                     PIKNLEDLYDKEGYRDDQFDKNDKGTWIVRSSMSIQSNGKDMNIKGMVLYMNRNTRTT
                     NGYYYVDVIEREDKGIHRDNEKRYPVKMVDNKIIPTKEIKDEKIKKEIENFKFFVQYG
                     DFKDLSKYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYNIPTNKAPKLLLKGIG
                     NLKGSSIGYKKIEFTFVEKKGENIYFSDGLHFNPSEDK"
     gene            26060..26830
                     /locus_tag="RFE25_001088"
     CDS             26060..26830
                     /locus_tag="RFE25_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2816172.1"
                     /translation="MMKRLNTLVLYISFLILIISIVAGCGTGKEAEIKKSFEKTLSMY
                     PIKNLEDLYDKEGYRDDEFDKNDKGTWTISSEMAIQKKGEALNIKGMVLKLNRNTRSA
                     KGFYYVNAIKKDENGRPQDKQIEYPVKMIDNKIIPTKDIKDEKIKKEIENFKFFAQYG
                     NFKDLTKYKGGDISYNPEAPIYSAKYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGSG
                     NLDGSSIGYKKIEFTFVEKKGENTYFTANLHFKPSNDE"
     gene            26895..27665
                     /locus_tag="RFE25_001089"
     CDS             26895..27665
                     /locus_tag="RFE25_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2816173.1"
                     /translation="MMKRLNKLVLGISFLFLVISITAGCGMGKEAEIKKSFEKTMSMY
                     PIKNLEDLYDKEGYRDDQFDKNDKGTWIVNSQMAIQNKGEPMKSKGMVLYMNRNTRTT
                     NGYYYVNVIKGEDKGKHQDNEKRYPVKMVDNKIILTKEIKDENIKIEIENFKFFVQYG
                     NFKDLENYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGTG
                     NLKGSSVGYKDIEFTFVEKKEENIYFSDGLIFKPSEDK"
     gene            27732..28499
                     /locus_tag="RFE25_001090"
     CDS             27732..28499
                     /locus_tag="RFE25_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2816174.1"
                     /translation="MKRLNKLVLYISFLILVISFTAGCGMGKEAEIKKSFEKTLSMYP
                     IKNLEDLYDKEGYRDDQFDKNDKGTWIINSEMVVQPKGERMKSKGMVLYMNRNTKTTT
                     GKYIVSETLHDEDGRPKSKDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGS
                     FKDLSKYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGD
                     LKGSSVGYKDIEFTFVEKKGENTFFTDSLHLEPSEDK"
     gene            28596..30833
                     /locus_tag="RFE25_001091"
     CDS             28596..30833
                     /locus_tag="RFE25_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020808042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2816175.1"
                     /translation="MQRDYLIRVETESMPDFKRLNGLMIGFVIKGEAHIYDENNMTQC
                     NSGDIFIINHRDLYRFQLQQDGIICYIQFQMKYLADKFDDAHCLYFHLTDATTTKNIH
                     QLRNIMARLVSTHIRHNELSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQV
                     CDYIELHFHEDLSLSELSEYVGWSESHLSKKFTESLGVGFQHFLNTTRIEHAKLDLTY
                     TDETITDIALQNGFSSAASFARTFKHFTHQTPKQYRGDRPAITENQQSAQHNYHDREL
                     ILLLNDYIEEMNHFIEDIEKMNYKEIAFKPTNQQLNQFNHIIQVGYLRNLLNTQYQSQ
                     LLTCHHDFQVNEVLAYDVMPYIMKKLNAPFTYDAEISNIFYDIDLCLDFLLDHNFSLT
                     MHLNQYDSRDYIDAFKVFIHHVALHVSHRKDLKFNLYVTTLHTSLIEMIDYFKALFPN
                     GGLYIHLDQATERHLPLLKRLEPHINHFVFDANSNDAVDFNKMNDDEFKTASQMIINK
                     TNYLIDLMHRHNLKRPLILLNWNTLTGDTFITNGEYFRGGIIIEQLLKLSTKVEGIGY
                     WLNYDLHVSHCRNERDYMNSIELFHQYNGKRPVYFTALLFNKLTSNILYSDDTCIVTG
                     TDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLNINALEDGMYKIKHFTLDKENGA
                     LFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDITDTLALNIKMITNGIHLIEVK
                     RYPSS"
     gene            30984..32162
                     /locus_tag="RFE25_001092"
     CDS             30984..32162
                     /locus_tag="RFE25_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDU2816176.1"
                     /translation="MNQQLIEALKSKEDKMIEIRRYLHQHPELSFHEDETAKYIAEFY
                     KGKDVEVETNVGPRGIKVTIDSGKPGKTLAIRADFDALPITEDTGLSFASQNKGVMHA
                     CGHDAHTAYMLVLAETLAEMKDSFTGKVVVIHQPAEEVPPGGAKAMIENGVLDGVDHV
                     LGVHVMSTMKTGNVYYRPGYVQTGRAFFKLKVQGKGGHGSSPHMANDAIVAGSYFVTA
                     LQTVVSRRLSPFETGVVTIGSFDGKGQFNVIKDVVEIEGDVRGLTDATKATIEKEIKR
                     LSKGLEDMYGVTCTLEYNDDYPALYNDPEFTEYVAKTLKEANLDFGVEMCEPQPPSED
                     FAYYAKERPSAFIYTGAAVEDGEIYPHHHPKFNISEKSLLISAEAVGTVVLDYLKGDN
                     "
     gene            32164..33552
                     /locus_tag="RFE25_001093"
     CDS             32164..33552
                     /locus_tag="RFE25_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2816177.1"
                     /translation="MNETYRGGNKLILGIVLGVITFWLFAQSLVNVVPNLQQSFGADM
                     GTISIAVSLTALFSGMFVVGAGGLADKIGRVKMTNIGLLLSIIGSALIIITNLPALLI
                     LGRVIQGVSAACIMPSTLAIMKTYYQGAERQRALSYWSIGSWGGSGICSLFGGAVATT
                     MGWRWIFIFSIIVAVLSMLLIKGTPETKSEITNTHKFDVAGLIVLVVMLLSLNVVITK
                     GAALGYTSLWFFGLIAIVIVAFFIFLNVEKKVDNPLIDFKLFENKPYTGATISNFLLN
                     GVAGTLIVANTFVQQGLGYTALQAGYLSITYLIMVLLMIRVGEKLLQKMGSKRPMLLG
                     TFIVVIGIALISLVFLPGIFYVISCVVGYLCFGLGLGIYATPSTDTAISNAPLDKVGV
                     ASGIYKMASSLGGAFGVAISGAVYVGAVAATSIHTGAMIALWVNVLMGIMAFIAILFA
                     IPNDDKRVKDAK"
     gene            complement(34036..35697)
                     /locus_tag="RFE25_001094"
     CDS             complement(34036..35697)
                     /locus_tag="RFE25_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDU2816178.1"
                     /translation="MSVTEVIFSFLGGLGIFLYGLKIMGDGLQASAGDRLRDILNKFT
                     SNPVLGVIAGIVVTILIQSSSGTTVITIGLVTAGFMTLKQAIGVIMGANIGTTVTAFI
                     IGIDLGEYAMPILALGAFLIFFFKRSKINNIGRILFGFGSLFFGLEFMGDAVKPLASL
                     DGFKQLMLDMSSNPILAVIVGAGLTALVQSSSATIGILQEFYQQDLISLNAAIPVLLG
                     DNIGTTITAILASLAGSIAAKRAALVHVIFNLIGVIIFTIFLPVVIHLISLLQDVWHL
                     KPAMTIAVSHGTFNITNTLIQLPFVAGLAWIVTKLVPGKDIADDYKPQHLNKDLVYHA
                     PGVALQETQKELQNVGQIVLSMFEDIREITKDDKKLIKKLEQKHQAVETINDSIRNYL
                     VRISTKAITKADVERLAVMFDVNRSILKVAELTEEYVAQLKRQHDEDIRITEDAQRGM
                     DKLFNHVAESFDKAIDMLDVYDKTKKDEIVERSRESFNIEHKLRKGHIKRLNRGECTT
                     KGGLLYIDMIGVLERIGYHSRNVSEALVGLNDDVPTDEEIATTEI"
     gene            complement(36022..37797)
                     /locus_tag="RFE25_001095"
     CDS             complement(36022..37797)
                     /locus_tag="RFE25_001095"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HDU2816179.1"
                     /translation="MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRD
                     GQMEGSKIHILEELPKAGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEI
                     DNASVLDEFYWLNKEDPNYSRCRVIEKQGQRLVTDGDFTLTKTAIKEILDLCLTNEED
                     LDDVKITDVFSDDFFNSNFWIYWKTMFAFEPWHSAMEMRRYLMRFVHHIGGLADFSAL
                     KFTKYNQYESLVLPMVEYLKSHGVQFEYDVKVEDIKVDVTTSQKIAREILIHRHGKAE
                     SIKLTVDDLVFVTNGSITESSTYGDNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDK
                     FCQNIPKKSWFVSATSTTNNKEIIDTIESICKRDPLAGKTVTGGIITINDSAWQMSFT
                     INRQQQFKDQPENEISTWIYALYSDVNGDYIKKPITECSGNEICQEWLYHLGVSTDKI
                     EDLAKHVSNTIPVYMPYITSYFMTRAIGDRPLVVPHQSQNLSFIGNFAETERDTVFTT
                     EYSVRTAMEAVYQLLNIDRGIPEVINSTFDLRVLMDAVYELNDHQDLREITKDSKMQK
                     LALAGFLKKIKGTYIETLLKEHKLL"
     gene            complement(37971..38843)
                     /locus_tag="RFE25_001096"
     CDS             complement(37971..38843)
                     /locus_tag="RFE25_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDU2816180.1"
                     /translation="MNKLRDTTFLSYLFTIILWGSAFPMIKIALNDFSAESLSAFRLI
                     LATIILLPFVIIKKLPTPELRDIPVIFILGFCGFVIYHTALNFGETLISAGISGILVS
                     TTPIFSSALAYIFLKEHFSKWNWLSSLVAFIGISIISISKDDYTTINVLGVFIILLAS
                     FSESLYFTFQKKYIEKYGFIAFTLYTIMASSPFMLIFIPEIINDIHGATFTSIVSVLY
                     LAIFPTIIPYVLLAYIVKSVGVSDATMSLYLTPIVSLLLSYLLLDELPTTLAIIGGII
                     TLLGVSLSNFFQNT"
BASE COUNT        14100 a         5538 c         6739 g        12489 t
ORIGIN      
        1 ccatatgaaa ctaaacgcgt attagatcca acaatggaac caggtagtcc tgataaagta
       61 gctcaaaaag gtgaaaatgg tgaaaaaaca acaacaacac caactacaat taatccatta
      121 acgggagaaa aagtaggcga aggcgaacca acaacggaag taacgaaaga accaatagac
      181 gaaattgtta actatgcacc tgaaattatt cctcatggta cacgtgaaga aattgatcca
      241 aacttaccag aaggtgaaac taaagttatc ccaggtaaag atggcttgaa agatcctgaa
      301 actggagaaa tcattgaaga accacaagat gaagtaatca tccatggtgc taaagatgat
      361 tcagatgcgg acagcgattc agacagcgat agcgattcag acgcagatag cgattctgat
      421 gcagacagcg actcagacgc agatagcgac tcagattcag acgcagatag cgactcagat
      481 tcagacagcg actcagacgc agacagcgac tcagattcag acagcgattc agacgcagac
      541 agcgactcag acgcagatag cgactcagat tcagacagcg attcagacgc agatagcgat
      601 tcagattcag atagtgactc tgatgcggac agcgactcag acgcagatag cgactctgat
      661 gcggacagcg attcagacgc agatagcgat tcagattcag atagcgactc tgatgcggac
      721 agcgactcag attcagacag cgattcagac gcagatagcg actcagattc agacgcagat
      781 agcgattctg attcagacag cgactcagac agcgatagcg attctgattc agacagcgac
      841 tcagacagcg atagcgattc agacgcagat agtgactctg atgcggacag cgactcagac
      901 gcagatagcg actctgatgc ggacagcgac tcagacgcag atagcgactc agattcagac
      961 agcgatagcg attctgatgc agacagcgac tcagacgcag atagcgactc tgatgcggac
     1021 agcgattcag acgcagatag cgactcagat tcagacagcg attcagacgc agatagcgac
     1081 tcagattcag acgcagatag cgattctgat tcagacagcg actcagacgc agatagcgac
     1141 tctgatgcgg acagcgactc agacgcagat agcgattctg atgcagacag cgactcagac
     1201 agcgatagcg attctgattc agacagcgat tcagacgcag atagcgactc tgatgcggac
     1261 agcgattcag acgcagatag agatcataat gacaaaacag ataaaccaaa taataaagag
     1321 ttaccagata ctggtaatga tgctcaaaat aatggcacat tatttggttc actattcgct
     1381 gcgcttggag gattattctt agttggcaga cgtcgtaaaa acaaaaataa tgaagaaaaa
     1441 taatatttaa acttcataat tttgggtaaa atttaaaacc aggccttaca tggcctggtt
     1501 ttattttaaa tactatgata taaattaatg gaaataggac aaatatataa aaataaggag
     1561 gaaacaatgg aatttgaaca taaattagag aaattaatat ctgaagtaaa taataagact
     1621 gaaattaata attatgtttt ttttagttta ggtaagtcaa gtgttaaagc acaggttaag
     1681 ttattaaaaa aaactaatta tctcaaacaa gatatttcaa aattggcact taaatttaaa
     1741 aagaaatctg gggaatttcc tgagtggatt aaattagata ttgtaacctc gactgaaaaa
     1801 atattattta aagaattaaa aaaaacactg atcaatacaa gaagaaatta tgtagatttt
     1861 ggtatagcat ttgatagtca atggaatttt gcagtattac ctgaagaaat taacgcgaat
     1921 gcttttgttc gaccagataa tactactaaa gagttatttc tttcggaaaa aaacatcaat
     1981 aattatttac gcaaatatac tacaaataaa aaggcatttt ctagtgagtt ctataatgaa
     2041 aaagaagtta ttaaattcta tacacaaggt ttctttatag gtgatgaaga agtacatgaa
     2101 ctatatagcg aaggctataa aaaaggttta agaaaagtaa atgatttaaa taatgaaatt
     2161 gatcaattaa ttgaaagtag tactaatttc ttacaaaata tgttgttaga taatggtaaa
     2221 tatatttatg gatattttcc tcattttgat aatgaaattg gattctacaa tgttttaaga
     2281 cactcttctt ctacttatgc cttaattgag ggtctgtcct atttaggtaa aagcttacaa
     2341 cctgttgaaa aagcaattga ttatatcatt ttaaatcaac tgtttgagat tggtgataaa
     2401 gcctatatct ttgatgatac agaggaagca aatgaaatca aattaggaca aaatgcttca
     2461 tttatattcg cagtttgtga atatttaaag catgaagata atcctaaatt tcttgagtca
     2521 gctcagaaag tggctaaagg tattctttca atgatagatg aagatacata tgagacaact
     2581 cacttattga attatcctga tttaagcgta aaagagaagt ttagaattat ttattacgat
     2641 ggtgaagcag cgcttgcttt attgagattg tatcaaaagg atgaaaatga actatggcta
     2701 aaaactgtag aaaatttgat ggaccgtttc attgagaaga aatattggca atatcatgat
     2761 cattggttag gatattgtac gaatgaatta gttcaaatta atccacaaga caaatatttt
     2821 gaatttggaa tcaaaaatgt gaataattac ttagattata ttaaaaatcg tgaaacaaca
     2881 tttccaacat tcttagaaat gttaatggcc acatatagat tagttcaaaa agcgaaagat
     2941 acgggtcgcg aggaattggt aaacaattta atagatgaac aatatttgat agatgtaatt
     3001 aatattagag cagattatca aagagttgga ttcttttatc ctgaaattgc tatgtatttt
     3061 aaaaacccat caagaatact aggaagtttc tttattaaac accacggtta tcgtgttcga
     3121 attgatgata tcgaacatta tttatctgga tatgtacaat atcagcttgc atttaatagg
     3181 taaaataagt atttgaaatt taaattaatg acttacaaaa aatggttgat ttacataaaa
     3241 acgaaatcaa ccatttttaa tttgctcttt aataattatt tttcatataa ctaaaattct
     3301 aatttcataa agaataactg aaaaaactaa acaacatgtg agctattcat aacttgaatt
     3361 aattgtagaa aatctatctt cccataactt cataacaatt ttacttgaaa aagctttaga
     3421 gtgcttgata cattcttgag aaaaagtatc tcttaaagtc ttatctaata ataggtttcg
     3481 cactcgatta tataattcat ctttatcatt tttgttaatt aaataaccat tttcattatt
     3541 taatattaat tcggaaggac catacttcga attatagcca actggaggta tgccttcagt
     3601 tatagtttct aataaaccta aattaaatcc ttccatatta ctagtaatta gagacatata
     3661 agcatcttga atctcagcac ttaaatttct tctaaaccct cgtaaaaaca cattgttttc
     3721 taaattatat tcagtgatta gttgcttgta tttttcttct tctttaccaa acccatacaa
     3781 atgtagttgg atgttaggaa attctttaat taatttagaa actaattcaa tttgatgatt
     3841 caactgtttt tcaggagaat aacgtgcaac ggaaataatt ttattattat ttatactatg
     3901 attatttctt tttaaattag taaaatgttc atcaatatat cctactggta tagtatgaac
     3961 agggatttca ttatttattc gagctgatat atccaattgt tgctgtttag tcgatacaat
     4021 tatcccagag tatctattta gattgttaaa aacatgttta taagtatttt tgatgtccga
     4081 ttcatatacc atgtcaatat tcttgacatg agtactatgc aaaacagcta aaacaggtat
     4141 tgtttcacta gtattattga atattggtgc agtatttata tttttatcac tcaggaaaat
     4201 atctccattt ttatacaatt tttcaattgc aaatgctagt aattcctgat cattattaaa
     4261 atacttaagt tgagaatcgg tgttataaat aataagttgt gattgtgaat tttcaagttc
     4321 tggattaaaa aatttttgga actttatagt accttcagga gtgtaataat gttcacaaac
     4381 tactttttga tttgttgtta aagttcttga acaacttaaa aagcctcttg aatcatatag
     4441 atctcgacgt attttacgtt gatttacatc aaaatgattt atgtaatcca aatgttggta
     4501 attactatca ttaaaatgga catacattct atagttgctt ttttcatata tctttatatc
     4561 attggtattt tcaataaatt ttagtgtata attacactct ttagtccaat gagtgatcca
     4621 gtccttatgg atgcttttta tatttatact gtcttgtagc acatcatata agcttaatat
     4681 atcgtcatct tcaatttgaa atagacttgc attaaaatgt aaacgaggtg accacgatgc
     4741 aaaaatcaat ttactagtta tcgagtgatt tttaaataag ttgtgtctat taatcatcgc
     4801 tttttcaatt ccggttaatt tatttcctaa cctattccct actgaatata tcattttaat
     4861 tcaacctcat tttttgttat ttattattta gtttattttt aatttcattt aagtttgggt
     4921 aagaggtaaa tataataaat ttatctttat cttttataat accgctatta tatttcctgc
     4981 caataattat ttcgttagta aatttaaata gggtattttt atatgctttt aaaattttaa
     5041 ataagtcgtc aacagtgaag ttttgtcgtt ctctcatagt atgacgtcca gttaaattta
     5101 ttgctacaga atttgaaaga cttaaatgtt ctatttttga attgatatat tcatcgcgct
     5161 ttggaccgtt ttcaaataaa tacttagata attcataaga aggtgtatac ataggtgaat
     5221 taagcatggc tttcatcaat tcgtaagttg tcgtttcttt tccttcataa taaagtttgt
     5281 tatttgttgc ccagttagca ataaaaatag tatcttctga tacattatca tctatagctt
     5341 ttaaataatt aaagataggg cctaagcctt caattgtacc tgaatgttct ctgttatgag
     5401 attcaatgac attataattt tcatcaataa tcatataact gcgaccgttc aaggattgac
     5461 catcaaataa agaagtgttc gaattattaa tattatattt atttaatttc tcaggtaatt
     5521 cttttgctaa ttttggaaat tctgtaccac ctgctgatga ttttaataga gttaatgaat
     5581 ctggtttatt taggtacaat aaatcttttt ctaatagatg tctattagaa taccatgtta
     5641 tatttttgct ttttactcct gtaacgacac tctttaaagc atcatccata catagaatat
     5701 aatctgcatt actattttct agaacatcaa ctaattgcaa atgcaatgat ttagagtgct
     5761 tacctaagtc actaatttgc ccaatcgcaa taattttatt acctttaaaa aattttgttt
     5821 gagtattaaa tgcttttata gcattaatca ttgctggtaa tgaagcgttg tgtgtatcat
     5881 ctatgtaagt taactttata gttaggtgtt tcaacttctt ttaggtttaa aactttttca
     5941 aatggtttaa atgtacttaa gttctctaag gctctttcta gtggtatatc taaatgcgat
     6001 aatgtagcaa atgtggctag agagttttca accataccgt cacttattga attaattcta
     6061 taagtatatt tttgtccgtt aaaatcaatt gttataactg tatagccttt actatattga
     6121 atagatttag gacaaattgt tgcgctagag tcatgtgtac tataagtaat aacattactt
     6181 gtattttgtt tggcgcgttc gattaatata tctgaatgta atgtatcttt attaattatt
     6241 gctactccct caggagttaa accatcaaaa atacttgctt tcacttctac aatatttaga
     6301 atatctttaa atgtagacat atgagcagca cctataccag taactatagc aatatttggt
     6361 tttattaaat atgatgaatt accaactgca tttaatgcgt ttaatgatac ttctaaaaca
     6421 gcaaaatttg gttgtctaat cattttgcat aataataaat atactgcgga tcttatgtta
     6481 ttattaaatc tattttgaag aggataataa tctttaagac cagcacttat cagcattcta
     6541 gttgaacttt ttcccattga tcctgttata gcaacaacag ggtgtttata ctgtagtctc
     6601 atttcttcag ctaatttagt tagtgtgttt gcagaatcat tgataactaa ttgaggagtt
     6661 ttaaacttca tgtcaggaac ataggtttca gtaataatta atcctaaatc ttccttatcc
     6721 ttctttatat attcattacc ttcttttgcg tttgcatctc taccaaaacg tctccatgta
     6781 tgcttattgg gcgatatgta ggctgtgctt ttattatgaa taaaggggaa ccaattctca
     6841 aaattattta taacattgtc ctctttacct tcagcatcaa ggagattacc tcctaaaata
     6901 ttatgaagtt ctttaattgt taatgacatt ttgtactcct ttataaaatg taaaattgtg
     6961 tttaatttct aaatatatat atagtatagc atgttgatat actgaaatga tttgaaaaat
     7021 ttttgaaact taatgactta tatattcata ttagtttaaa attcgatact attccataat
     7081 gatggaatgt gatgtatatg attaatcaat atacatcaca tttcatttaa tgcaactatt
     7141 gcacaagtta atagtatatt taaaaatagg ttagtgagat tgattaatta ttgattatgt
     7201 tggtatcaat gaaagcttgg aagaagggct taaaaatata aaaacttgga taaatcacaa
     7261 tacaatcata gacacagata agttcgtcaa tctgttaatg aattatgatg tgatagagtt
     7321 aagtgaggat aaatgttaac gttttattaa aacagtcaca gaattagata gagcatttgc
     7381 aatttgtgct actgaactta taatctaaga gctcaatagt gaaattgtct tttttaaagt
     7441 tgttaaagca taaatttgtt gaattattac agaaaaagat cgaaatttag ttactgctaa
     7501 tggaacggca gcattagagt ttgccgaact cattttaaaa ggacttgaat ttgatagtaa
     7561 agaaaatatt gaaaggcaaa tctatatgta tcaaagaggc ttctatgagt attgtaataa
     7621 gtatggcaat ccttatcaat aattaaaaac cgcatcatta tctgatacgc agaggcgtat
     7681 cataagtaaa actaaaaaat tctgtatgag gagataataa tttggagggt gttaaatggt
     7741 ggacattaaa tccacgttca ttcaatatat aagatatatc acgataattg cgcatataac
     7801 ttaagtagta gctaacagtt gaaattaggc cctatcaaat tggtttatat ctaaaatgat
     7861 taatatagaa tgcttctttt tgtccttatt aaattataaa agtaactttg caatagaaac
     7921 agttatttca taatcaacag tcattgacgt agctaagtaa tgataaataa tcataaataa
     7981 aattacagat attgacaaaa aatagtaaat ataccaatga agtttcaaaa gaacaattcc
     8041 aagaaattga gaatgtaaat aataaggtca aagaatttta ttaagatttg aaagagtatc
     8101 aatcaagaaa gatgtagttt tttaataaac tatttggaaa ataattatca taatttaaaa
     8161 actgacaatt tgcgagactc ataaaatgta ataatggaaa tagatgtaaa atataattaa
     8221 ggggtgtaat atgaagatta atatttataa atctatttat aattttcagg aaacaaatac
     8281 aaatttttta gagaatctag aatctttaaa tgatgacaat tatgaactgc ttaatgataa
     8341 agaacttgtt agtgattcaa atgaattaaa attaattagt aaagtttata tacgtaaaaa
     8401 agacaaaaaa ctattagatt ggcaattatt aataaagaat gtatacctag atactgaaga
     8461 agatgacaat ttattttcag aatccggtca tcattttgat gcaatattat ttctcaaaga
     8521 agatactaca ttacaaaata atgtatatat tatacctttt ggacaagcat atcatgatat
     8581 aaataatttg attgattatg acttcggaat tgattttgca gaaagagcaa tcaaaaatga
     8641 agacatagtt aataaaaatg ttaatttttt tcaacaaaac aggcttaaag agattgttaa
     8701 ttatagaagg aatagtgtag attacgttag accttcagaa tcttatatat cagtccaagg
     8761 acatccacag aatcctcaaa tttttggaaa aacgatgact tgtggtacaa gtatttcatt
     8821 gcgtgtaccg aatagaaagc agcaattcat agataaaatt agtgtgataa tcaaagaaat
     8881 aaacgctatt attaatcttc ctcaaaaaat tagtgaattt cctagaatag taactttaaa
     8941 agacttgaat aaaatagaag tattagatac tttattgcta aaaaaactat cgaattcttc
     9001 aactacagaa aatatatcta tagatatatc aagattttta gaactaagta atatgatact
     9061 cttgttagat gatatgctcg acgtcaatat atatataaat tcttttaaaa ataatacatt
     9121 agagacattt gatgcgactg atcctgaagt tgattacatc actgaaatag gagattactt
     9181 attaaaatat gacgttaatt ctataaatga tgtcagaatt gaagtgatag ataatttggg
     9241 gcattcaaat aatatgctac taaaaacgat actacatgca gaagttgaaa tggaagatgg
     9301 aaagaaatat ttattacaaa atgggaaatg gggttatttt aatagagaat tttttgacct
     9361 tttgaatgat catttgaatg agatagaaat taggtataac acactaactc ctacaggttt
     9421 agtatttaaa gaaggagaag aaggatatat aaaagaaata gtaggaagat tgccagaaga
     9481 atatttaatg ttacataaaa aattcataaa accaataaat aagaatttta tagtaaaagg
     9541 aaatggaata gagttggcag acttatacaa tattaaaaac aaagagcttt tcacgattaa
     9601 aagaggaatt aatacatctt tatctcttta tagtctagaa cagaatataa tagcaattaa
     9661 cgccttaaaa tatccagaat catataattt tgaagaatta atagaagcta ttcctgataa
     9721 ctcggaaaat atatttaatg atatacaacg gagtacaaat tttagtatag tatggatttt
     9781 accgatatca tctattgata atatgcccat aaagatatgg ttcatactag taacgtaata
     9841 aataaaaact ttcaattaac taatttaggt tcagtattac ttaaaaataa attagtagag
     9901 tggtctctct atttaaaaga tcaaagaatt aatccaatta tttatatgga aacgccaact
     9961 gaagatagaa attaaacttt tattttaaat caccctagtt catacctaaa agactttcac
    10021 acaaacaaac aaaggaggaa acttaaattc ctcctttccc ttattactca tactataatt
    10081 caattttaac gtcttcgtcc atttgggctt caaattcatc tagtaatgct cgtgcttctg
    10141 caattgattg tgtgttcatc aattgatgtc gaagttcgct agcgctctta tgccacgcac
    10201 atagatttta aagaatctac gcaaactctt gaattgtcgt atttcatctt tttcatattt
    10261 gttaaacaat gataaatgca atctcaacag atctaatagt tccttgcttg tgtgttcgcg
    10321 tggttctttt tcaaaagcga atggattatg gaaaatgccg ctaccaatca tgacgccatc
    10381 aatgccatat ttttctgcaa gttcaagtcc tgtttttcta tcgggaatat gggagtggga
    10441 cagaaatgat attttcccaa aatttatttc gtcgtcccac tccaacttgc acattattgt
    10501 aagctgactt tccgccagct actatgttgg ggcccctgac tagaattgaa aaaacttgtt
    10561 acaagtgcat tttcgttcag tcaactactg ccaatataac tttgtagagc atagaacatt
    10621 gatttatgtc ccaacctgca atttcgtcac gtaaattttt aatagcttcg attaattccc
    10681 actgtgcatc tactttacta atgtgtttga taaaaactta aataatttta attcagtcat
    10741 cagtggcatt aaatcttcta tcatttttag ttatagttga taaatttata tttataagca
    10801 tatatatgga tatttcatca agaattttta atcatataaa tccgaactgc atacatattt
    10861 gttgaaataa gaggtattat ttttcgggaa attgctgtct gagttataag tattagtttt
    10921 ataaaatgag ttgaactata gcaaaaacga ttaaaatact gataatccat ttttgtatta
    10981 tgttagggac ttttttactt aattttaacc ctattggagc aaatataata ctccctatta
    11041 taaggaataa ggcgtcatat aaagggatat aaccttgaat aagtttgatg acaaaagcac
    11101 caattgaaga tataaaagca attactatac tattagcgac tacagtattc attggtaatt
    11161 tgaataaaac caataatata ggaataataa tgaaggcacc acctgcacct actatacctg
    11221 aaataatacc aatgaaaagg ccaatgataa ctaataaata tttattaaat gaagactttt
    11281 cggaactagg tttcacttta ataaacatta atgttaatgc aagtaaagca ataatgatat
    11341 ataccgtatt tacaaatgta gcatcaaata aatttgctag aaatgcacct aacatactcc
    11401 ctataatcat gccgccaccc atataaagaa ctaattgtgg tgagaactct gttttttttc
    11461 gagcttttaa tgagccactt aatgtactga aaaagacttg gctagaagta agacctgatg
    11521 cgatatatgc gctatatgca ggggctccga ataatggtgg taataataaa atagctggat
    11581 aaataatgat agcaccacct acgcctacta gaccagatat gaacccaccg aataccccaa
    11641 tgagtaacat gataactata ttaacaatat ccattactta cttttcacca ataagtttac
    11701 agcttcatta attaactctt gggagctttc ttcatcatcc gcagctactt ttacacattc
    11761 tattaaattc tcactaataa tgatacccat caagcgttgg agtgaactct ttgatgcact
    11821 tatttgtgta atgacatctt tacagtcttt tccttcctcc atcattttaa taattccatt
    11881 tagttgccct tgtattctat taatacgatt aatcattttt ttatcataat tcatagtcat
    11941 acctccactt ttaattgaat aaaaatatat taatagataa acacaaatgt gtcaaatacc
    12001 cctagaggta tttgacaagt tccattcaac cgtttagaat acccctacag gtatttttag
    12061 ggaggttatt atgaaacaat acggagaaaa gtttatcgat gaatttagta aagcagaatt
    12121 ggaaaaacta gccaagcaag ggcaattaat tgatgttaga acagaagagg agtatgcatt
    12181 aggacatatc aatggttcca tacttcatcc tgttgatgag attgagtcat tcaataaaga
    12241 aaaaaataaa acctattatg taatctgtag aagtggtaac agaagtgcta atgctagtaa
    12301 atatttagct aaacaaggtt ataacgttat aaatcttgat ggtggttata aagcttatga
    12361 agaaaacgat agttatgata cacaagaaga atataaaagt atagaaatta aagcagatcg
    12421 taaacaattt aactatcgtg gttttcaatg tccagggcca attgtaaaaa ttagtcaaga
    12481 aatgaagaat attgaagtag gtgaccaaat tgaagtcaaa gtcacagacc ctggattccc
    12541 tagtgatatt aaaagttggg tgaaacaaac aaggcatact ttagttaagc ttgatgaaaa
    12601 taacaatgga attaatgcga ttattcaaaa agaaaaagca aaagatttag atataaatta
    12661 ttctgctaaa ggtactacaa ttgtattatt tagtggagaa ttagacaaag ctgtagcagc
    12721 attgattatt gcaaatggcg ctagagctgc tggaaaagat gtaactatct tctttacttt
    12781 ttgggggctt aatgcattaa aaaaagtgca aacagttaat gttaaaaagc aaggtattgc
    12841 aaaaatgttt gatttaatgt tgccccaaaa gaatatacga atgcctcttt ccaaaatgaa
    12901 tatgtttggt ttaggaaata tgatgatgcg ctacgtaatg aaaaagaaaa atgttgattc
    12961 attaccaaca cttatcaatc aagctattga gcaaaatatc aaattaatcg cttgtacgat
    13021 gagtatggat gtcatgggta ttcagaaaga agaacttaga gatgaagttg agtacggtgg
    13081 tgtaggcact tatattggtg ctactgaaaa tgcgaatcat aatttattta tctaattaaa
    13141 tctattaata aaaggagttg ttatcatgtt ttttaaacag ttttacgata atcatttatc
    13201 tcaagcatca tatttagtgg gttgtcaacg tacaggagag gcaataataa tagaccctgt
    13261 tcgtgattta tcgaaatata tagaagttgc agattctgaa ggtttaacaa ttacacaagc
    13321 tacagaaaca catattcatg ctgattttgc ttcaggaatt cgtgatgtgg ctaaacgctt
    13381 aaatgcaaat atatatgtgt ctggcgaagg tgaagatgca ttagggtata aaaatatgcc
    13441 atcaaaaaca caatttgtta aacatggaga tatcattcaa gtaggcaatg ttaaattaga
    13501 agttctgcat actccaggac acacgcctga aagtattagc tttttactca ctgatttagg
    13561 tggtggttca agtgttccga tgggattatt tagtggtgac tttatttttg ttggtgatat
    13621 aggtagacct gatttattag aaaaatctgt tcaaataaag ggttctacag aaattagcgc
    13681 gaaacaaatg tatgagtccg ttcaaaatat taaaaattta ccagactatg ttcaaatctg
    13741 gccgggtcat ggtgctggaa gcccttgtgg taaagcatta ggtgccatac ctatatctac
    13801 aataggttat gagaaaatta ataactgggc atttaatgaa attgatgaga ctaaatttat
    13861 tgaatcatta acatcaaatc aaccagcacc accgcatcat tttgcacaaa tgaaacaagt
    13921 taatcagttt ggtatgaatt tatatcaatc atatgatgtt tatcctagtt tagataataa
    13981 gagagtagca tttgatcttc gtagcaaaga ggcctttcac ggtggccaca caaaaggaac
    14041 aatcaatata ccatacaaca aaaactttat taatcaaatt ggttggtact tagattttga
    14101 aaaagatata gatttaattg gagataaatc tactgttgag aaagcgaaac acactttaca
    14161 attaattggg tttgataagg tagcaggcta tcgtttgcca aaatcaggca tttcaaccca
    14221 gtccgttcat agcgctgata tgacaggtaa agaagaacat gtattagacg tacgtaatga
    14281 tgaagagtgg aataatggac acttagatca agcagttaat attccacatg gtaaattatt
    14341 aaatgaaaat attcctttta ataaagagga taaaatatat gtacattgtc agtcaggtgt
    14401 tagaagttca attgcagtgg gtatattgga aagcaaaggt tttgaaaatg tggtgaatat
    14461 tagagaaggc tatcaagatt ttccagaatc attaaaataa tttaaggatg tggaaaaaat
    14521 gaataagcat tatcaaattg ttattattgg tggcggtaca gcaggtgtta ccgtagcatc
    14581 aagactatta agaaaaaatc aaaacttaaa agagaaaata gcaattatag acccagcaga
    14641 ccatcattac tatcaaccat tatggacgtt ggttggtgca ggggtatcta gtttgaaaag
    14701 ttctcgtaaa gatatggaaa gtgttatacc tgaaggtgct aactggataa aacaggctgt
    14761 ttcaagtttt caacctgaaa ataatagcgt tattttagga gataatacag tcgtttatta
    14821 tgatttttta gtagtagctc caggattaca gattaattgg tcttcaatta aaggactaaa
    14881 agaaaatata ggtaaaaatg gtgtttgctc taactattca cctgactatg ttaacgaaac
    14941 ttggaaccaa atttctaatt ttaaacaagg aaatgccatt tttacgcatc caaacactcc
    15001 tataaagtgt ggaggtgcgc ctatgaaaat tatgtattta gctgaagatt attttaggaa
    15061 acataaaatc cgttctaacg ctaatgtgat atatgcaacg ccaaaagatg ctttatttga
    15121 cgtaggaaaa tataataaag aattagaaag gattgttgaa gaaagaaata taacagtcaa
    15181 ttataattat aaccttgttg aaatcgacgg tgacaaaaaa gtggctacat tcgaacatat
    15241 caaagcatac gatagaaaaa caataagtta tgatatgtta catgtaacac cacctatggg
    15301 tcccttagat gtagtaaaag aaagtacact ttcagatagt gagggttggg tagatgttaa
    15361 cccaaccaca ttacagcata aaagctactc taatgtattt gcacttggtg atgcttcaaa
    15421 tgtacctact tcaaaaacag gcgcagctat tcgtaagcaa gcacctatcg tcgctaataa
    15481 tttattgcaa gtgatgaata atcaaatgtt aacgcatcat tatgatggtt atacttcatg
    15541 ccctattgtt actggatata ataggttaat acttgcagag tttgattata ataaaaatac
    15601 taaagaaaca atgccgttta atcaggccaa agaacgtaga agtatgtata tatttaagaa
    15661 agatttatta cctaaaatgt attggtacgg catgctaaaa ggattaatat aataaagtac
    15721 agaaaacaat aaatttttaa tgaaaaatct tttactataa aagattaagt atttaaatga
    15781 cgtgtcagtg ttgtgtttat atgtcgtgaa tttttagctc taaatagtat aagattgaaa
    15841 aagttgttac tgttttaaat gatcacgatg aagtcattca ataagaatga ttatgaaaat
    15901 agaaacagca gtaagatatt ttctaattga aaatcatctc actgctgttt tttaaaggtt
    15961 tatacctcat cctctaaatt atttaaaaat aattaatggt atttgagcac gtttagcgac
    16021 tttatgactg acattaccaa tttccatttc ttgccagata ttcaaaccac gtgtactcaa
    16081 aatgatagct tggtatgtac ctccaatagt aatttcaata actttgtctg ttgaacacta
    16141 agagcaattt taatttcata atgtgttgta aacatttttt ttgattggag tttttttctg
    16201 agttaaacga tatcctgatg tatttttaat tttgcaccat ttccaaaagg ataagtgaca
    16261 taagtaaaaa ggcatcatcg ggagttatcc tatcaggaaa accaagataa tacctaagta
    16321 gaaagtgttc aatccgtgtt aaattgggaa atatcatcca taaactttat tactcatact
    16381 ataattctat tttaacgtct tcgtccattt gggcttcaaa ttcatctaga agtgctcgtg
    16441 cttctgcaat tgattgtgtg ttcatcaatt gatggcgaag ttcgctagcg cctcttatgc
    16501 cacgcacata gattttaaag aatctacgca agctcttgaa ttgtcgtatt tcatcttttt
    16561 catatttgtt aaacaatgat aaatgcaatc tcaatagatc taatagttcc ttgcttgtgt
    16621 gttcgcgtgg ttctttttca aaagcgaatg gattatggaa aatgcctcta ccaatcatga
    16681 caccatcgat gccatatttt tctgccagtt caagtcctgt ttttctatcg ggaatatcac
    16741 cgttaattgt taacaatgta tttggtgcaa tttcgtcacg taaattttta atagcttcga
    16801 ttaattccca atgtgcatct actttactca tttctttacg tgtacgaaga tgaatagata
    16861 aattggcaat atcttgttcg aagacgtgct tcaaccaatc tttccattca tcgatttcat
    16921 agtagccaag gcgtgtttta acacttaccg gaagcccacc tgctttagtt gcttgaataa
    16981 tttcggcagc gacatccggt cttaagatta agccggaacc cttacccttt ttagcaacat
    17041 ttgctacagg acatcccata tttaagtcaa tgcctttaaa gcccatttta gctagttgaa
    17101 tactcgtttc acggaactgt tctggcttat ctccccatat atgagcgacc atcgggtgtt
    17161 catcttcgct aaaagttaag cgtccgcgca cactatgtat gccttcaggg tggcaaaagc
    17221 tttcagtatt tgtaaattca gtgaaaaaca catccggtct agctgcttca cttacaacgt
    17281 gtcgaaagac gatatctgta acgtcttcca ttggcgccaa aataaaaaat ggacgtggta
    17341 attcactcca aaaattttct ttcataatat atttataccc tctttataat tagtatctcg
    17401 attttttatg catgatgata ttaccacaaa agcctaactt atacaaaagg aatttcaata
    17461 gttgcaacca tttgaaaggg aagtctaaga gtagtctaaa ataaatgttg tggtaagttg
    17521 atcaatacaa agatcaagga ttatagtatt aaattgttca ttattaatga tacactactt
    17581 atgaatatga ttcagaattt tctttggcta cttttacagt aaagcgattt tttagttatc
    17641 ttataacaaa gacaaattta taaaggtgat attatggaag atttaaagga atctttaaaa
    17701 agtttaggtt ggtgggattt attttttgcg atacctatgt ttctgctatt cgcatacctt
    17761 ccaaactata attttataac gatatttctt aacattgtta tcattatttt cttttccata
    17821 ggtttgattt taactacgca tataattata gataaaatta agagcaacac gaaatgaatc
    17881 attaatacga atgtgattaa acataaaact gaaggagcga ttacaatggc gactaagaaa
    17941 gatgtacatg atttattttt aaatcatgtg aattcaaacg cggttaagac aagaaagatg
    18001 atgggagaat atattattta ttatgatagt gtggttatag gtggtttgta tgataataga
    18061 ttattggtta aggcgactaa aagtgtacgt catcaattgc aagataatac attagtttcg
    18121 ccatatccag gtgccaaaga aatgatatta attccagaca ttaccgaagc aataaatctc
    18181 actaatttat ttgagctcat aaaaaatgat ttgaaaaact aatcataaat tgccatactc
    18241 aactattttg aaaagtatca atttcatatt atcaaattat tgagtatctc gatttattgt
    18301 tatacacaaa cagtattttt gctatgatag agttaataaa tataataaat tgaataagta
    18361 actttacaaa actagaatga ttcaattcaa tcacaattat ttgaaaatag aggtgagcag
    18421 gtgaacgata tgttaattag tctcgtaatc ccagtttttg ctttgttagt tattggtggt
    18481 attatttggg tgattataga aggtatagta catatttcaa aaaagaataa agcaatcgat
    18541 aactttttaa accaagttaa taaagtaagt gagacatata aattcgctac tgctttttta
    18601 tttctaatct tggctacggc tggtatttct caattttatc tatattatat agtatcagcg
    18661 tttctttttt ggcttgtcat acttaccttt ggtattgcag gtatcatttt tttaatgcca
    18721 tatggattat gtttcctacc actttataag caaaaaaaga aaaaacagac atttaaaaaa
    18781 tacatggttt acactacgat tggtttgtca atttgtctag gcttatctct agttttggtt
    18841 cacactacga aaatttatat ggacgaaggt ggcgtaagat actattacgg tagttttgta
    18901 atgaaacaag cgggcggtta tgcttattta gctttagcgg tactttcaac gttgttaatt
    18961 gttgcgaaaa aagctacaaa taaaaataaa gaaatcgaaa ccgtcgacaa tacaaatata
    19021 acggaaagat aattaaggga gtgctcattc aggagtgctc ttttttgatg tccaaattta
    19081 gttgcaaatg aaggcataga agaaattttt atagtcattt attggataat aaattatggt
    19141 catatcgatt aattttatta gtgaggattt tacaaacatt tgttgaataa atatggtaat
    19201 gataatatat gaatattttt gaaaaaacac taatatgatt aaattatttg ttaaaatagc
    19261 attaagtaaa aaacaaatag ggaacaaggt gggatttcat gagtcaattg ctaaatgata
    19321 cgttatcggc ttggttgtta attgaatctt taagtccagg agaagtaaat tttacagcgg
    19381 aagatatact ctcagctgaa cattttaaaa atggtgcaaa gcaagcacaa cttcaaagtt
    19441 ttgatgaata ttttgaaata tggaattctg aacgctttat tatatcagaa gaaaaatcag
    19501 agactgggga acttatattt aaattttata gacattgctt ccgctataat gaaattaatt
    19561 tgaaaattca ggatattttt gatgattatt ctgatattca taatccaaat gggacacact
    19621 gttatggtta cacatttaac acagataaac acggcaaagt gatagttgat tctatacata
    19681 ttccgatgat tatgagtgca ttaaaagaaa ttgaaaagaa caaaaatgcc aatatagaag
    19741 aaaaatttaa tgattctgtt gaaaaatttt ttcaaaaagt aaaagaaatt ttagcagatg
    19801 aaccaattaa tgaatttaaa ttgaagaaga tggacaaagc ttatgatgag tacttttctg
    19861 tattaaattc aaagaaagat ggattatttg gacattatgt agcaatagaa tatgtgaaag
    19921 atagtgattt accacagccg gaatttaaca gtttcttcat aagtgatatt gagaaagcaa
    19981 gaaaatctcc caaccaaact ttaattgatt acattgaagg tgtagaagaa agtcagcgca
    20041 tagaagtaga tgaaaataaa gaaatgtttg acaaattttt acatccttca cgtttgcctg
    20101 atggacgatg gccatcacag actgagttta gattgtcttt aatgcaacaa cttgctgtaa
    20161 accaaattac gagtggtaat gaaagaataa gttcagttaa tgggccacca gggacaggta
    20221 agactacttt attaaaagat atatttgctc atctagtagt tgaaagaggt aaagagttag
    20281 ctaaactaaa taatcctaaa gatgcatttg tcaaaacaaa aattcatgaa acggatgata
    20341 aatacgtata cttactaaag gaatctattg ccaaatataa gatggtagtc gcatctagta
    20401 ataatggagc tgttgaaaat atatctaaag atttaccgaa aattgaagaa attataagaa
    20461 atcccgaaaa atgtaaattc cctaaatatg aacagaatta tgcaaattta gcacatgaat
    20521 taaaagattt tgctgaaata gctgaagatt tgattggtga aagtgcctgg ggcttatttt
    20581 ctggagtttt tggtaaaagt actaatatta accaagtatt gagtcatatg ttaaaacaag
    20641 atgcgaatga tattggcttt gctaaattac tacaaaatga gaataatcgt atgagttata
    20701 acgagttaat gagtgaatgg caatcacatc aacgtgcatt tttagaagag ttgaggcatg
    20761 ttgaaatgtt aaaagaagaa tctattagag catatgatgt ttataaaaat tgtgagtctt
    20821 tctctaagat tgaacaggtt attaatagtg aaaaaacaag tattgaagaa caggtatatc
    20881 atttagataa tgaaacgtta cgagacaata aagaaataga agatttggat aatcgaatta
    20941 attatattgt taagcaaata gaaactttaa atgagttaat taaatccatc aaagaaagca
    21001 acaaaggttt tattaacaaa ctgaaagcga tgtttaattc agaagaagat gaaagctata
    21061 aagatcataa taaagagaag caacaattat taacacaaca gttagagtta gagaaatgta
    21121 aaaaaaacaa acatgaagac cttgttagca aactaaaaga aaaagagaaa ttaattaaac
    21181 aattaactaa agtacagttg caattagacg agttaaattc acagttacaa gagttagaag
    21241 catatcgtat tgagtcaaaa attacaattc cagaaaaaga tttttggagt gacaacaatt
    21301 atgatgagcg ccaagttact aatctgtgga cgagtgacga acttcaatac agacgtgcca
    21361 tgctcttttt aagagcaatg atattgcata aattattatt gattgctaat aatacaacta
    21421 tttattatgc gattaatgat tttaaagata gaaggaaatt aattgatgca aatccagata
    21481 aagtacacaa cgcatggaat gtgatgcatt taatatttcc agtagttagt acgacgtttg
    21541 caagctttaa atctatgtat gggggcatac caaaagattt catagactac ttatttattg
    21601 atgaagcagg acaagcaata cctcaagcag ctgtgggagc attatatcgt tcaaaaaaag
    21661 ttgtagctgt aggtgatccg attcaaatag aaccggttgt gactttagaa agtcatttaa
    21721 ttgataacat tcgtaaaaat tatcatgttc cggaatatct agtttctaaa gaagcttctg
    21781 tgcagtctgt tgcagacaac gccaatcaat atggtttttg gaaatctgat gctactgata
    21841 gtaatcaaaa aacctggata ggcatacctt tatgggtgca cagacgatgt ttaaaaccta
    21901 tgttcacgat agctaaccaa atcgcttata ataataaaat ggtgttgcca agtaatatta
    21961 caaaagtagg taaaacaggt tggtatgacg ttaaaggaaa cgcagttcaa aaacaatttg
    22021 tgaaagagca tggtgaaaaa gtagtgggat tattagctga tgattggatt gaagcaatta
    22081 aggaaggtaa aaatgaaccg agctcatttg taatatcgcc tttttcagca gtacagcaac
    22141 agattaaacg tatgttaaag caacaactac cgactagaat tgatattgaa cgtacaaaaa
    22201 ttaatcaatg ggtcgataaa tccattggta ctgttcatac ttttcaaggt aaagaggctc
    22261 agaaggtgta ttttgtaata ggtactgata atacccaaga tggtgctgtg aactggtcat
    22321 gcgaaaaacc aaacttgtta aacgttgcag tgacaagagc taagaaagag ttttatgtaa
    22381 ttggcgacat gcaaagaata cagatgaaac cattttatga gacgattttt aaagaaagaa
    22441 atgtaaaata acatacaaaa aagtatatag aggaagttat acattttaaa aggagcaaaa
    22501 ttgaataatg gagaaattta acaactggat attaaatgca ataagtggat ctcaaacaga
    22561 caagaatgaa acaactgaag aattaaaagg ggcaaaattt atcattttat atgcatattc
    22621 aatgctcgtt ttgcttgcgt tagtaatttc taacatattc attcacattt tggagcctaa
    22681 actatcaatc accactcaaa tcatcatcgt tttgatttta attgaagcac taattggact
    22741 gcgtttcttg aaagcgtacg atgttaagcg tggcaaagat aaagaaaata agaaaaatag
    22801 taaggatttc gttaaactaa aatcaatttt agtagcaatt ttatttacat cattggcgct
    22861 gacagcaggt actgtagctg atatatacgg tttcactgac ttaggaaata ctagaagtga
    22921 tttaatcgtt tggagcatag gtggtattat atttggcctc gtatgttaca caatggaaga
    22981 taaaaaataa cgataaggag ctggcgatta taaagctagc tcctttttta acttatatat
    23041 gtaaagcact atcctaaggg tctttaatca tatgtcaata attcctataa ttaatactct
    23101 taaatattgt ttaaataagt tttaaaattt tacacatatt tttatttaaa aaagatgtat
    23161 aattaatgta ttaaatatag aaagaagttg atattatgaa aaagtgtatt aagactttgt
    23221 ttttaagtat cattttagta gtgatgggtg gttggtatca ttcagcacat gcgtcagatt
    23281 cgttgagtaa aagtccagaa aattggatga gtaaacttga tgaaagcaaa catttaactg
    23341 agattaatat gccaggctca catgatagtg gctcattcac tttaactgat ccggtaaaat
    23401 cggtttgggc aaagactcaa ggcaaagatt accttactca aatgaagtcg ggagtcaggt
    23461 tttttgatat tagaggtaga gcaagtgctg ataatatgat ttcagttcat cacggcatgg
    23521 tttatttgca tcatgaacta ggaaaatttt tagatgatgc taaatattac ttgagtgctt
    23581 atccaaacga aacaattgtg atgtctatga aaaaggacta cgatagcgat tctaaagtta
    23641 cgaagacatt tgaagagatt tttagagaat attattataa taacccgcaa tatcagaatc
    23701 ttttttacac aggaagtaat gcgaatccta ctttaaaaga aacgaaaggt aaaattgtcc
    23761 tattcaatag aatggggggt acatacataa agagtggtta tggtgctgac acgtcaggta
    23821 ttcaatgggc agacaatgcg acatttgaaa cgaaaattaa taatggtagc ttaaatttaa
    23881 aagtacaaga tgagtataaa gattactatg ataaaaaagt tgaagctgtt aaaaatttat
    23941 tggctaaagc taaaacggat agtaacaaag acaatgtata tgtgaatttc ttgagtgtag
    24001 cgtctggagg tagcgcattt aatagtactt ataactatgc atcacatata aatcctgaaa
    24061 ttgcaaaaac gattaaagaa aacgggaaag ctagaactgg ttggctgatt gttgactatg
    24121 caggatatcc gtggcctgga tatgatgata tcgtaagtga aattatagat agtaataaat
    24181 aaggattcaa taatgatatt aagacgagta tgaaaatagt tagattctaa ttattttcac
    24241 tactcgtttt tattttgaaa ataagtaata attcaacaat attataaatt gaacagattg
    24301 tttgtgaaat ttttgataat attaaagtga aaaagtgtta taaattgata aatatatgta
    24361 attaacaaaa acaaatcatt ttaaaaagaa gagagttgta agatgatgaa acgattaaac
    24421 aaattagtgt taggcattat ttttctgttt ttagtcatta gtatcactgc tggttgtggc
    24481 ataggtaaag aagcggaagt taagaaaagc tttgaaaaaa cattgagtat gtaccctatt
    24541 aaaaatctag aggatttata cgataaggaa ggctatcgtg atgatcagtt tgataaaaat
    24601 gataaaggta catggattat aaattctgaa atggttattc aacctaataa tgaagatatg
    24661 gtagctaaag gcatggttct atatatgaat agaaatacca aaacaacaaa tggttactac
    24721 tatgtcgatg tgactaagga cgaggatgaa ggaaaaccgc acgacaatga aaaaagatat
    24781 ccggttaaaa tggtcgataa taaaatcatt ccaacaaaag aaattaaaga taaaaacata
    24841 aaaaaagaaa tcgaaaactt taagttcttt gttcaatatg gaaactttaa agatttgtcg
    24901 aagtacaaag atggagatat ttcatacaat ccagaggtgc caagttattc agcaaaatat
    24961 caagtaacta atgatgatta taatgtaaaa caattacgta aaagatatga tataccgacg
    25021 aataaagcac caaagttatt gttgaaaggt acaggtaatt taaaaggctc atcagttgga
    25081 tataaagata ttgaatttac tttcgtggag aaaaaaggtg aaaatatata ctttagtgat
    25141 agtctacatc ttgaaccaag tgaggataaa taaacgtgac caataaagag tatgaaatcg
    25201 aacccggaaa aagagagtga tgaaatgata aaacgtgtaa ataaattagt gctaggtatt
    25261 agttttctgt ttttaatcat cagtatcttt gctggttgtg gtacagggaa agaagcggaa
    25321 ataaagaaaa gttttgaaaa aacgttgagt atgtatccga ttaaaaatct agaggattta
    25381 tacgataaag aaggatatcg tgatgatcaa tttgataaaa atgataaggg aacatggatt
    25441 gttcgttcgt caatgtcgat tcaatctaat ggaaaagata tgaatataaa aggcatggtt
    25501 ttatatatga atagaaatac aagaacaaca aatggctatt actatgttga tgttatagaa
    25561 agagaagata aaggtataca tcgtgataac gaaaaaagat atccggttaa aatggtcgat
    25621 aataaaatca ttccaactaa agaaattaaa gatgaaaaaa taaaaaaaga aatcgaaaac
    25681 tttaagttct ttgttcaata tggcgacttt aaagatttgt cgaagtacaa agacggcgat
    25741 atatcataca atccagaggt gccgagttat tcagcaaaat atcaattaac taatgatgac
    25801 tataatgtaa aacaattacg aaaaagatat aatataccaa cgaataaagc accaaagcta
    25861 ttgttgaaag gtatagggaa tttaaaaggt tcatcaattg gctacaaaaa aattgaattt
    25921 actttcgtag agaaaaaggg agaaaatata tactttagtg atgggctaca ttttaatcca
    25981 agtgaggata aataatcatg attcgatcaa attatgaaat cgatccagga aaaacaataa
    26041 aaagaaatag gattgtgaaa ttatgaaacg attaaataca ttggtattgt acatcagttt
    26101 tttgatatta atcatcagta tcgttgctgg ttgtggtaca gggaaagaag cggaaataaa
    26161 gaaaagtttt gaaaaaacat tgagtatgta tccaattaaa aatctagagg atttatacga
    26221 taaagaaggc tatcgtgatg acgaatttga taaaaatgat aaaggaacgt ggactattag
    26281 ttctgaaatg gcaattcaga aaaagggaga agccttaaat ataaaaggta tggttttgaa
    26341 gttaaataga aatacaagga gtgcaaaagg attttactat gttaatgcga taaagaagga
    26401 tgaaaatggc agacctcagg ataagcaaat agaatatccc gttaaaatga ttgacaataa
    26461 aatcattcca actaaagata tcaaagatga aaaaataaaa aaagaaatcg aaaactttaa
    26521 gtttttcgcg cagtatggca attttaaaga tttgacgaag tataaaggtg gagatatttc
    26581 atataatcca gaagccccga tttattcagc aaaatatcaa ctaaccaatg atgattataa
    26641 tgtaaagcaa ttacgtaaaa gatatgatat accgacgaat aaagctccaa agttattgtt
    26701 aaaaggttca ggaaatttag atggttcatc aattggatac aaaaaaattg aatttacttt
    26761 cgtagagaaa aaaggagaaa acacttactt tacagctaac ctacatttta aaccgagtaa
    26821 tgatgaataa tcgtgactaa taaagagtat gaaatcgatt caaggaaaca aaataaaaag
    26881 aagagagttg taaggtgatg aaacgtttaa ataaattagt gttaggtatt agtttcttat
    26941 ttttagtcat tagtattact gctggttgtg gcatgggtaa agaagcggaa attaagaaaa
    27001 gttttgaaaa gacaatgagt atgtatccga ttaaaaacct agaggattta tatgacaaag
    27061 agggctatcg agatgatcaa tttgataaaa atgataaggg aacatggatt gtaaattctc
    27121 aaatggcaat tcaaaataaa ggagaaccta tgaaatcaaa aggcatggtt ctgtatatga
    27181 atagaaatac aagaacaaca aatggctatt attatgttaa tgtgattaag ggcgaggata
    27241 aaggtaaaca tcaagacaat gaaaaaagat accctgttaa aatggtcgac aataaaataa
    27301 tccttactaa agaaattaaa gatgaaaaca taaaaataga aatcgaaaac tttaagtttt
    27361 ttgttcaata tggaaacttt aaagatttgg aaaattataa agatggagat atatcatata
    27421 atccagaggt gccaagttat tcagctaaat atcaattaac taatgatgat tacaatgtaa
    27481 agcaattacg taaaagatat gacataccaa caaataaagc accgaagttg ttgttgaagg
    27541 gtacagggaa tttaaaaggt tcatcagttg gatataaaga cattgaattt acgtttgtag
    27601 agaaaaaaga agagaacatt tactttagtg atgggttaat ttttaaacca agtgaggata
    27661 aataatcatg actcgattaa aatatgaaat caatccagga aagataataa taagaatagg
    27721 attgtgaaat tatgaaacga ttaaacaaat tggtattgta tattagtttt ttgatattag
    27781 tcattagttt cactgctggt tgtggcatgg gtaaagaagc ggaaataaag aaaagttttg
    27841 aaaaaacatt gagtatgtat ccgattaaaa atctagagga tttatacgat aaagaaggct
    27901 atcgtgatga tcaatttgat aaaaacgata aaggcacatg gattattaat tctgaaatgg
    27961 ttgttcaacc taaaggggaa cgtatgaaat caaaaggtat ggttctatat atgaatagaa
    28021 acactaagac tacaaccggg aagtatatag tgagtgaaac acttcatgat gaagatggta
    28081 gacctaagag taaagataaa gaatatccgg ttaaaatggt agacaataaa atcattccaa
    28141 ctaaaggtat caaagacgaa aatataaaaa aagaaatcga gaattttaag ttcttcgcgc
    28201 aatatggcag ctttaaagat ttgtcgaagt acaaagacgg cgatatatca tataatccag
    28261 aggtaccgag ttattcagca aaatatcaat taactaatga tgactataat gtaaaacaat
    28321 tacgaaaaag atataaaata ccaacgaata aagcaccaaa gttattgttg aaaggttcgg
    28381 gagacttaaa aggttcatca gttggatata aagacattga atttactttt gtggagaaaa
    28441 aaggtgaaaa tacttttttt actgatagtc tacatcttga accaagtgag gataaataat
    28501 ctcctgcctc ccacacgatt caacacgaat ttcaaatatg ttgctgtaaa ataatgtaaa
    28561 ataaacgtat tcatattact gaattgaggg atagtatgca acgtgattat ttaattcgag
    28621 tagaaactga aagcatgcca gatttcaaaa ggctcaatgg tttaatgatt ggttttgtta
    28681 ttaaaggtga ggcacatatt tatgatgaaa ataacatgac gcaatgcaac agtggcgaca
    28741 ttttcatcat taaccaccgt gacttgtatc gatttcaact tcaacaagat ggcatcatat
    28801 gttatatcca attccaaatg aaatatttgg cagacaagtt tgatgatgcg cattgtctat
    28861 attttcactt aacagatgcg accacaacca agaatataca tcaactgaga aatataatgg
    28921 caagactggt ttcaacacac attcgacata atgagttgtc taaattgact gagcaacaac
    28981 ttgtgattca gttgcttatg catatgattc attatgtccc gcgtacatat cattcgaacc
    29041 aaagtatctt aaatgatgat aaagtgaatc aagtatgcga ctatatcgag ttacattttc
    29101 atgaagattt aagcctttca gaattaagcg aatacgttgg gtggtcagag agccatctgt
    29161 ctaaaaagtt tacagaatcg ctaggtgtag gattccaaca tttcttaaat acgacgcgaa
    29221 ttgagcatgc gaaactcgat ttaacataca cagatgaaac gattactgat attgcattgc
    29281 aaaatggctt ttcaagtgca gcgagctttg cgagaacatt taaacacttt acgcatcaaa
    29341 cgcctaaaca atatcgaggt gatcgtccag caatcactga aaatcaacaa tcggcacaac
    29401 ataattatca cgaccgtgaa ttgatattac ttttaaatga ctacattgaa gaaatgaatc
    29461 atttcattga agatattgaa aagatgaact ataaagagat tgcctttaaa ccaactaatc
    29521 aacaactaaa tcaatttaat catattattc aagtgggcta tttgaggaat ttgctcaata
    29581 cacagtatca atcacagttg cttacatgtc atcatgattt tcaagtcaat gaagtattag
    29641 catatgatgt gatgccatat attatgaaaa agctcaatgc gccattcacg tatgatgcag
    29701 agatttcgaa tatattttat gatatcgatt tgtgtttaga ctttttatta gatcataact
    29761 ttagtctaac catgcatttg aatcagtatg actcacgaga ttatatcgat gcattcaaag
    29821 tatttatcca tcacgttgcc ctgcatgtca gtcatagaaa agatttgaag ttcaacttgt
    29881 atgtgacgac attgcacacg tctttaattg aaatgattga ttattttaaa gcattattcc
    29941 ctaatggtgg cttgtacatt cacttagatc aagctacgga aagacatcta ccattgttga
    30001 aacgacttga gccacacatc aaccattttg tatttgatgc caattcaaat gatgctgttg
    30061 attttaataa aatgaatgat gatgaattta aaaccgcgag tcaaatgatt attaataaaa
    30121 cgaattacct tatcgactta atgcatcgcc ataacctaaa gcgtccactc attttactca
    30181 attggaatac attgacgggt gatacattta ttacaaacgg cgaatatttt agaggtggta
    30241 tcatcattga gcaattatta aaattaagta ctaaagtaga gggtatcggg tattggttga
    30301 attatgattt gcacgtcagt cattgtagaa atgaacggga ttatatgaat tctattgaac
    30361 tgtttcatca atataatgga aaacgtccgg tctatttcac ggcattgcta tttaataaat
    30421 taacaagcaa tattttgtat tctgatgata catgtattgt cacgggaact gattcaaatt
    30481 ttcaaatatt gttatatgat gcaaagcatt ttaatccgta cttagcgttg gacaatcaaa
    30541 tgaatatgcg tgcaacggaa atgatccatt tgaacattaa tgccctagaa gacggtatgt
    30601 ataagattaa acattttacc ttagataaag aaaatggtgc gttatttaat ctttggcgca
    30661 aacatcatac gatacatggc atggacaagg actctataga ttacgttaat cgaatgagtt
    30721 ttccgaaatt agaagtatat gatatagata tcacggacac actggcatta aacattaaaa
    30781 tgattacgaa tgggattcac ttaattgaag taaaacgtta cccaagttca taaaatgatc
    30841 acaaatcaca aattttgata tacataattt gtgatttttt atattcaaag ctaaaattgc
    30901 aaaaaattaa tggttaacat ctctgttgtt ggcaatataa ataatgatta atcatttatg
    30961 atgtaactaa ggagatgaag gatatgaatc aacaattaat tgaagcttta aaatctaaag
    31021 aagacaaaat gattgagatc agacgttatt tacatcagca tccagaatta tcttttcatg
    31081 aagatgaaac ggcgaaatac atcgctgaat tttacaaagg taaagatgtg gaagtagaaa
    31141 cgaatgtcgg accacgtgga attaaagtaa cgattgattc agggaaacct ggtaaaacat
    31201 tagcaatccg tgcagacttt gacgcattac ccattactga agatacagga ttatcttttg
    31261 catcacaaaa taaaggtgtt atgcacgcat gtggtcacga tgcacataca gcttacatgc
    31321 ttgtattagc agagacgctt gctgaaatga aagatagttt tacaggaaaa gtcgttgtga
    31381 tacatcaacc agctgaagaa gtaccaccag gtggtgctaa agcaatgatt gaaaatggtg
    31441 tattagacgg tgttgatcat gtattaggtg tacacgtcat gagcacaatg aaaacaggta
    31501 atgtgtatta cagacctggt tatgttcaaa caggacgcgc attcttcaaa ttgaaagttc
    31561 aaggtaaagg tggtcatggt tcatcaccac atatggccaa tgatgccatt gttgcaggta
    31621 gctacttcgt cacagcgtta caaacagttg tatctagacg actaagtcca tttgaaaccg
    31681 gtgttgtcac aatcggttca tttgacggta aaggtcaatt caatgtcatt aaagatgttg
    31741 ttgaaattga aggtgatgta cgtggattaa cagatgctac aaaagcaaca attgaaaaag
    31801 aaattaaacg tttatcaaaa ggattagagg atatgtatgg tgtaacttgc accttagaat
    31861 ataacgatga ttatccagca ttatataatg atccagagtt tactgagtac gtggctaaga
    31921 cgttgaaaga agcaaacctt gattttggtg ttgaaatgtg tgaaccacaa ccaccttcag
    31981 aagactttgc atattatgct aaagaacgtc caagtgcctt tatttataca ggtgcagctg
    32041 tggaagatgg tgaaatttac ccacatcatc atcctaaatt taacatttca gaaaaatcat
    32101 tacttatttc ggcagaagct gtagggacag ttgttttaga ttaccttaaa ggagataact
    32161 aacatgaatg aaacgtatcg cgggggcaac aagttaatct taggtattgt attaggtgtt
    32221 attacatttt ggttgtttgc acaatcactt gtaaatgttg taccaaattt acaacaaagt
    32281 tttggtgcag acatggggac aattagtata gcggtcagtc taactgcact attttcaggt
    32341 atgtttgtcg ttggagcagg tggtctagca gataaaattg ggcgcgtgaa aatgacgaat
    32401 atcggtttat tgttaagtat tattggttca gcattaatta ttattacgaa tttaccggca
    32461 ttattaattt taggtcgtgt tatacaaggt gtatcagcag cgtgtattat gccttccaca
    32521 ttggccatta tgaaaactta ttatcagggt gctgaacgtc agcgtgcctt aagttattgg
    32581 tctatcggtt cttggggtgg cagtggtatc tgttcactct tcggtggtgc agttgcgaca
    32641 actatgggtt ggagatggat tttcatcttc tcaattatcg ttgccgtact ttcaatgtta
    32701 ctcatcaaag ggacgcctga aacgaaatca gaaattacca atacacataa atttgacgtt
    32761 gcagggctaa ttgttctagt agttatgttg ctaagtttaa acgttgtcat tactaaaggt
    32821 gcagcacttg gttacacatc attatggttc tttggtttga ttgcaatcgt aattgtagca
    32881 ttctttattt tcttaaatgt tgagaaaaaa gtagataatc cacttattga ttttaaatta
    32941 tttgaaaata aaccatatac aggtgcaacg atttcgaact tcttattaaa cggtgttgca
    33001 ggtacattaa ttgtagcgaa tacattcgtg caacaaggtt taggttatac agcattgcag
    33061 gcaggatact tatcaattac ttatttaatc atggtgttat tgatgattcg agttggtgaa
    33121 aaattattac aaaaaatggg ttctaagcga ccaatgttat taggtacatt cattgtggtc
    33181 attggtattg cacttatttc attagtattc ttaccaggca tattttatgt tatcagttgt
    33241 gtcgtaggat atttatgttt cggactaggc ttaggtattt atgcaacacc ttctacagat
    33301 acagctattt cgaatgcacc gttagataaa gttggcgttg cttcaggtat ttataaaatg
    33361 gcttcatcac ttggtggcgc attcggtgtc gcaattagtg gtgctgtata tgttggtgca
    33421 gttgctgcaa cgagcattca tacaggtgcg atgattgcac tttgggttaa cgtattaatg
    33481 ggaatcatgg catttatcgc aattttattc gcgattccta atgatgataa acgtgtcaaa
    33541 gatgcgaaat aataacgatg acacgccaag tgttttgata atgatataaa tgaaagtaaa
    33601 gcaaattaaa tgaggaaatg tatagagcag tgcatataga taaatctatg attggattaa
    33661 cactaatata aatataaatg aaaaaccatc cacttaaact tttgataagt taggtggatg
    33721 gttatttatt gcgttgttct aaaaatttgg acatttatat agaaggaact atatataatg
    33781 tgaaggttat ggcaattcgc ttcaatgaag gcgacgtgaa agtgaatact aaatgattcg
    33841 aggtcagact ccgagaacag tgtccgtcat gcttaccgca tactaatgaa gcattattat
    33901 atcagtgttt atagccgatt taagataata aagtttgcta aacaaaaaag ccaatccatt
    33961 gatgttggat tgaccttgta tatgcctctg aatctctaat tttaaaaaat atgaatataa
    34021 ataagacatt aaaaattaaa tttcagttgt tgcaatttct tcatctgtag gtacatcatc
    34081 gttaagacca acaagtgctt cagaaacatt tcgtgaatga taaccgatac gttcaagaac
    34141 accaatcata tcgatatata gtaatccgcc ttttgttgta cattcgccac gattaaggcg
    34201 tttaatatga cctttgcgta gtttatgttc aatattaaat gattctctac tacgttctac
    34261 aatttcatct tttttcgttt tgtcataaac atctaacatg tcgatggctt tatcaaatga
    34321 ctcagcaaca tggttgaata atttatccat accgcgttgt gcatcttctg taatgcgaat
    34381 atcttcatca tgttggcgtt ttaattgagc gacatactct tctgttagct ctgctacttt
    34441 taaaatagag cgattgacat caaacataac tgctaaacgc tcaacgtctg ccttcgtaat
    34501 ggcttttgta gaaattctaa ctaaataatt tcgaatgcta tcattgattg tttcaacagc
    34561 ttggtgcttt tgttcaagct tcttgatcaa ttttttatcg tcttttgtaa tttcgcgaat
    34621 gtcttcaaac attgataaga caatctgacc cacattttgt aattcttttt gagtttcttg
    34681 taatgcaaca ccaggtgcgt gataaacaag atctttgttt aagtgctgag gtttatagtc
    34741 atcagcaata tctttacctg ggacaagctt tgtaactatc catgctaaac ctgctacaaa
    34801 tggtaattga atcaaagtat ttgttatgtt gaaggtacca tgtgatactg caatcgtcat
    34861 cgctggtttt aagtgccata catcttgtaa caaactaatc aaatgaatca caactggcaa
    34921 gaaaattgtg aagataatta ccccgattaa attaaagatg acgtgtacaa gcgccgcacg
    34981 ttttgcagcg attgagccgg ctaaactagc taagatagct gtaattgttg taccaatgtt
    35041 atcacctagt aacacaggga ttgctgcgtt taagctgatt aaatcttgtt gataaaattc
    35101 ttgtaaaata ccaatcgtcg cacttgaact ttgaactagt gctgttaacc ctgcgccgac
    35161 aatgacagca agtattggat ttgatgacat atcaagcatt aattgcttaa atccatctaa
    35221 tgatgctaaa ggtttaacgg catcacccat aaattctaga ccgaagaata gagaaccgaa
    35281 accgaatagt atgcggccaa tgttattgat tttagagcgt ttaaagaaaa agattaaaaa
    35341 tgcacctaat gctaaaattg gcattgcata ttcgcctaaa tctataccga taataaatgc
    35401 agttaccgtt gttccgatat tggcacccat tatcactcca atagcttgtt ttaacgtcat
    35461 aaatccagct gttaccagtc cgattgtgat aacggtcgta cctgaactac tttgtattaa
    35521 aatagttaca acgatacctg caataacacc taatactgga tttgatgtaa atttgtttaa
    35581 aatatctcgt agcctgtctc ctgctgatgc ttgaagcccg tctcccatga tttttaagcc
    35641 gtaaaggaaa atacctaaac cacctaaaaa ggagaaaatg acttctgtaa ccgacatttc
    35701 cattatttca cctcaaataa gctttatatt tagattatcg cttataattg taaatttaat
    35761 gttaagatta ggtaaaatta tttaacaata tatgttattt gtatatgact tgtaaaatat
    35821 cgtcacttat tatgtaaatt ttcagtgtga aatggcaggt ttgcaataaa ttgtttaaca
    35881 aaatgatgca atcaatcatg taattatgtt tcatcaaaaa aatcatgtga gtgggataac
    35941 gaaataaagt ttgtgaacat atcatttcta tcccactcca tgatttgaaa tcaccaaata
    36001 aaaatctatt aatggttttc gttataacaa tttgtgttct tttaataatg tctcaatgta
    36061 cgtacctttt atctttttaa ggaatcctgc taatgcgagt ttctgcattt tcgaatcttt
    36121 agtaatctcg cgcaaatctt gatggtcatt cagttcgtat acggcatcca ttaagacgcg
    36181 aagatcaaat gtactattga tgacctctgg aataccacga tctatattta gtaattgata
    36241 aacagcttcc atggcagtac gaaccgaata ttctgttgta aatacagtat ctcgctctgt
    36301 ttctgcaaag ttaccaataa atgataaatt ttgtgattga tgcgggacga ctaaaggtct
    36361 gtcgccgata gcacgcgtca tgaaataaga ggtgatatat ggcatataaa caggaatcgt
    36421 attagataca tgttttgcta agtcttcaat tttgtcagtt gatacaccta agtgatacag
    36481 ccattcttgg catatttcat taccactaca ttctgtaatt ggctttttaa tataatcgcc
    36541 gtttacatct gaatataagg cataaatcca tgtagatatt tcattttcag gttggtcttt
    36601 aaactgttgc tgacgattga ttgtaaaact catttgccat gcagaatcat tgattgtaat
    36661 aataccgcct gtaactgttt tgcctgcaag tgggtcacgt ttacaaatac tttctattgt
    36721 atcgataatc tctttattgt ttgttgtaga agttgctgaa acaaaccaac tttttttagg
    36781 aatattttgg caaaacttat caggattacc aaattcagga ctttgtcgcg ctaaattttt
    36841 ccatagtgtc caactaccac ctaattcgtc agttggtggt gctggtgtat cattatcacc
    36901 atacgtagag ctttccgtaa tactaccgtt tgtcacaaag acaagatcat ctacagtcag
    36961 tttaattgac tctgctttgc catgtcggtg aattaatatt tctcgggcaa ttttttgact
    37021 tgtcgtaaca tctactttaa tatcttctac ttttacatcg tattcaaatt gaaccccatg
    37081 cgattttaaa tattcaacca taggtaatac taaagattca tattgattat atttagtgaa
    37141 ttttaaagct gaaaagtctg cgagaccacc aatatgatga acgaatcgca ttagataacg
    37201 acgcatttcc atagcagaat gccacggttc aaatgcaaac atcgttttcc agtaaatcca
    37261 aaagtttgaa ttaaagaagt catcggaaaa tacatctgtt attttgacat catctaaatc
    37321 ttcttcattc gttaagcata aatctaaaat ttctttaatc gccgttttag tcaaagtgaa
    37381 gtctccgtct gtgactaaac gttgaccctg tttttcaata acacgacagc gagaatagtt
    37441 agggtcttct ttgtttagcc aatagaactc atctaataca gacgcgttat cgatttctaa
    37501 tgaagggata gatctgaata agtcccacaa acattcaaag tggttctcca tttcacgacc
    37561 accgcggaca acatagcctt ttaaaggcat attttcacca tcaagactac cacctgcttt
    37621 aggtaactct tctaaaatat gaatcttcga accttccatt tgaccatccc taattaagaa
    37681 acaagctgcc gcaagtgaag ctaacccaga cccgattaag taagcagatt tgttttctac
    37741 attttcaggt tttttagggc gcgcaaatgc ttcataattt ccataactgt aatacatatc
    37801 caccaagtcc tttcgtatta gaatacactc agactatacc cctttgtgaa ttgtaaatat
    37861 tagtatttat attggtaaat ttgacgaaat tagatcattt ttatattttt gatttttaaa
    37921 attttatcac tcgaatgttt ttggattctg aggtgcggga cttggaataa ttatgtattt
    37981 tgaaagaagt tacttaaact aacgcctagt agagtgataa ttccgcctat aatagcaagg
    38041 gttgttggta gctcgtctaa taacagataa gataataata aagaaacgat aggtgttaaa
    38101 taaagagaca ttgttgcatc agagacacca actgacttca caatataagc aagcaaaacg
    38161 tatggaatta tagtagggaa tatagctaaa taaagtaccg atactattga tgtaaaagtg
    38221 gcgccgtgta tatcgttgat gatttcagga ataaaaataa gcataaatgg tgagcttgcc
    38281 attattgtat atagtgtgaa agcgatgaag ccgtattttt ctatgtattt tttctggaaa
    38341 gtaaaataca aactttcact aaaagatgca agtaaaataa taaaaacacc taatacatta
    38401 atagttgtgt aatcatcttt acttattgaa ataatggata ttcctataaa tgcgacgagt
    38461 gaacttaacc aattccattt tgaaaaatgc tcttttaaaa atatataagc taaagcacta
    38521 gaaaaaatag gcgttgtaga gactagaatt ccagatatac ctgcactaat caaagtttca
    38581 ccaaaattta aagctgtgtg atatatcaca aatccacaaa atcctaaaat aaaaataaca
    38641 gggatatctc ttagttcagg ggtaggcaat ttctttataa ttacgaacgg caagagaatt
    38701 attgttgcta aaattaaacg aaatgccgac aatgattctg cactaaaatc atttaacgca
    38761 atctttatca ttggaaatgc agatccccac aatatgatag taaataaata tgatagaaaa
    38821 gtagtgtctc gaagtttatt cattaatatc atcactcctt taatta
//
LOCUS       DAPDIM010000020        38587 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000020 DAPDIM010000000
VERSION     DAPDIM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 38587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38587
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.020"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            80..1417
                     /locus_tag="RFE25_001097"
     CDS             80..1417
                     /locus_tag="RFE25_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDU2816181.1"
                     /translation="MKQPILNKLESLNQEEAISLHVPGHKNMTIGHLSQLSMTMDKTE
                     IPGLDDLHHPEEVILESMKQVEKHSDYDAYFLVNGTTSGILSVIQSFSQKKGDILMAR
                     NVHKSVLHALDISQQEGHFIETHQSPLTNHYNKVNLSRLNNDGHKLAVLTYPNYYGET
                     FNVEEVIKSLHQLNIPVLIDEAHGAHFGLQGFPDSTLNYQADYVVQSFHKTLPALTMG
                     SVLYIHKNAPYRETIIEYLSYFQTSSPSYLIMASLESAAEFYKTYDSTVFFDKRAQLI
                     ECLEKKGFEMLQVDDPLKLLIKYEGFTGHDIQNWFMNAHIYLELADDYQALAILPLWH
                     HDDTYLFDLLLRKIEDMILPKKSVSKVKQTQLLTTEGNYKPKRFEYVTWCDLKKAKGK
                     VLARHIVPYPPGIPIIFKGETITENMIELVNEYLETGMIVEGIKNNKILVEDE"
     gene            1419..2036
                     /locus_tag="RFE25_001098"
     CDS             1419..2036
                     /locus_tag="RFE25_001098"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDU2816182.1"
                     /translation="MSAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTG
                     EEIRKIVLEGNDMDIRTEAMLFAASRREHLVLKVIPALKEGKVVLCDRYIDSSLAYQG
                     YARGIGVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIKNSRDQNRLDQEDLKFH
                     EKVIEGYQEIIHNESQRFKSVNADQPLENVVEDTYQTIIKYLEKI"
     gene            2064..2393
                     /locus_tag="RFE25_001099"
     CDS             2064..2393
                     /locus_tag="RFE25_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HDU2816183.1"
                     /translation="MKMIIAIVQDQDSQELADQLVKNNFRATKLATTGGFLRAGNTTF
                     LCGVNDDRVDEILSVINQTCGNREQLVSPITPMGGSADSYIPYPVEVEVGGATVFVMP
                     VDAFHQF"
     gene            2607..3533
                     /locus_tag="RFE25_001100"
     CDS             2607..3533
                     /locus_tag="RFE25_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDU2816184.1"
                     /translation="MDEQQQLTNAYHSNKLSHAYLFEGDDAQTMKQVAINFAKLILCQ
                     TDSQCETKVSTYNHPDFMYISTTENAIKKEQVEQLVRHMNQLPIESTNKVYIIEDFEK
                     LTVQGENSILKFLEEPPDNTIAILLSTKPEQILDTIHSRCQHVYFKPIDKEKFINRLV
                     EQNMSKPVAEMISTYTTQIDNAIALNEEFDLLALRKSVIRWCELLLTNKPMALIGIID
                     LLKQAKNKKLQSLTIAAVNGFFEDIIHTKVNVEDKQIYSDLKNDIDQYAQKLSFNQLI
                     LMFDQLTEAHKKLNQNVNPTLVFEQIVIKGVS"
     gene            3534..4337
                     /locus_tag="RFE25_001101"
     CDS             3534..4337
                     /locus_tag="RFE25_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDU2816185.1"
                     /translation="MPNVIGVQFQKAGKLEYYTPNDIQVDIEGWVVVESKRGIEIGIV
                     KNPLMDIAEEDVVLPLKNIIRIADDKDIDKFNCNERDAENALILCKDIVREQGLDMRL
                     VNCEYTLDKSKVIFNFTADDRIDFRKLVKILAQHLKTRIELRQIGVRDEAKLLGGIGP
                     CGRSLCCSTFLGDFEPVSIKMAKDQNLSLNPTKISGACGRLMCCLKYENDYYEEVRAQ
                     LPDIGEAIETPDGNGKVVALNILDISMQVKLEGHEQPLEYKLEEIETMH"
     gene            4354..4701
                     /gene="yabA"
                     /locus_tag="RFE25_001102"
     CDS             4354..4701
                     /gene="yabA"
                     /locus_tag="RFE25_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499035.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HDU2816186.1"
                     /translation="MDRNEIFEKIMRLEMNVNQLSKETSELKAHAVELVEENVALQLE
                     NDNLKKVLGNDEPTTIDTANSKPAKAVKKPLPSKDNLAILYGEGFHICKGELFGKHRH
                     GEDCLFCLEVLSD"
     gene            4975..5700
                     /locus_tag="RFE25_001103"
     CDS             4975..5700
                     /locus_tag="RFE25_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDU2816187.1"
                     /translation="MLKENERFDQLIKEDFSIIQNDDVFSFSTDALLLGHFTKPRTKD
                     IVLDLCSGNGVIPLLLFAKHPRHIEGVEIQKTLVDMARRTFQFNDVDEYLTMHHMDLK
                     NVTKVFKPSQYTLVTCNPPYFKENQQHQHQKEAHKIARHEIMCTLEDCMIAARHLLKE
                     GGRLNMVHRADRLMDVLFEMRKVNIEPKKVVFIYSKVGKSAQTIVVEGRKGGNQGLEI
                     MPPFYIYNEDGNYSEEMKDVYYG"
     gene            5693..5941
                     /locus_tag="RFE25_001104"
     CDS             5693..5941
                     /locus_tag="RFE25_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDU2816188.1"
                     /translation="MDSHFVYIVKCSDGSLYTGYAKDVNARVEKHNRGQGAKYTKVRR
                     PVHLVYQEMYETKSEALKREYEIKTYTRQKKLRLIKER"
     gene            5943..6782
                     /gene="rsmI"
                     /locus_tag="RFE25_001105"
     CDS             5943..6782
                     /gene="rsmI"
                     /locus_tag="RFE25_001105"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDU2816189.1"
                     /translation="MAVLYLVGTPIGNLADITYRAVDVLKRVDMIACEDTRVTSKLCN
                     HYDIPTPLKSYHEHNKDKQTAFIIEQLELGLDVALVSDAGLPLISDPGYELVVAAREA
                     NIKVETVPGPNAGLTALMASGLPSYVYTFLGFLPRKEKEKSAVLEQRMHENSTLIIYE
                     SPHRVTDTLKTIAKIDATRQVSLGRELTKKFEQIVTDDVTQLQALIQQGDVPLKGEFV
                     ILIEGAKANNEISWFDDLSINEHVDHYIQTSQMKPKQAIKKVAEERQLKTNEVYNIYH
                     QIS"
     gene            7067..9040
                     /gene="metG"
                     /locus_tag="RFE25_001106"
     CDS             7067..9040
                     /gene="metG"
                     /locus_tag="RFE25_001106"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDU2816190.1"
                     /translation="MAKETFYITTPIYYPSGNLHIGHAYSTVAGDVIARYKRMQGYDV
                     RYLTGTDEHGQKIQEKAQKAGKTEIEYLDEMIAGIKQLWAKLEISNDDFIRTTEERHK
                     HVVEQVFERLLKQGDIYLGEYEGWYSVPDETYYTESQLVDPQYENGKIIGGKSPDSGH
                     EVELVKEESYFFNISKYTDRLLEFYDQNPDFIQPPSRKNEMINNFIKPGLADLAVSRT
                     SFNWGVHVPSNPKHVVYVWIDALVNYISALGYLSDDESLFNKYWPADIHLMAKEIVRF
                     HSIIWPILLMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPNILIDRYGLDATRYY
                     LMRELPFGSDGVFTPEAFVERTNFDLANDLGNLVNRTISMVNKYFDGELPAYQGPLHE
                     LDEEMEAMALETVKSYTESMESLQFSVALSTVWKFISRTNKYIDETTPWVLAKDDSQK
                     DMLGNVMAHLVENIRYAAVLLRPFLTHAPKEIFEQLNINNPQFMEFSSLEQYGVLTES
                     IMVTGQPKPIFPRLDSEAEIAYIKESMQPPATEEEKEEIPSKPQIDIKDFDKVEIKAA
                     TIIDAEHVKKSDKLLKIQVDLDSEQRQIVSGIAKFYTPDDIIGKKVAVVTNLKPAKLM
                     GQKSEGMILSAEKDGVLTLVSLPSAIPNGAVIK"
     gene            9071..9844
                     /locus_tag="RFE25_001107"
     CDS             9071..9844
                     /locus_tag="RFE25_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDU2816191.1"
                     /translation="MLIDTHVHLNDEQYDDDLSEVITRAREAGVDRMFVVGFNKSTIE
                     RAMKLIDEYDFLYGIIGWHPVDAIDFTEEHLEWIESLAQHPKVIGIGEMGLDYHWDKS
                     PADVQKEVFRKQIALAKRLKLPIIIHNREATQDCIDILLEEHAEEVGGIMHSFSGSPE
                     IADIVTNKLNFYISLGGPVTFKNAKQPKEVAKHVSMERLLVETDAPYLSPHPYRGKRN
                     EPARVTLVAEQIAELKGLSYEEVCEQTTKNAEKLFNLNS"
     gene            10011..10547
                     /gene="rnmV"
                     /locus_tag="RFE25_001108"
     CDS             10011..10547
                     /gene="rnmV"
                     /locus_tag="RFE25_001108"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDU2816192.1"
                     /translation="MKINEFIVVEGRDDTERVKRAVECDTIETNGSAINEQTLEVIRN
                     AQQSRGVIVLTDPDFPGDKIRSTITEHVKGVKHAYIDREKAKNKKGKIGVEHADLIDI
                     KEALMHVSSPFDEAYESIDKSVLIELGLIVGKDARRRREILSRKLRIGHSNGKQLLKK
                     LNAFGYTEADVRQALEDE"
     gene            10558..11451
                     /gene="rsmA"
                     /locus_tag="RFE25_001109"
     CDS             10558..11451
                     /gene="rsmA"
                     /locus_tag="RFE25_001109"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDU2816193.1"
                     /translation="MLDNKDIATPSRTRALLDKYGFNFKKSLGQNFLIDVNIINNIID
                     ASDIDAQTGVIEIGPGMGSLTEQLARHAKRVLAFEIDQRLIPVLNDTLSPYDNVTVIN
                     EDILKANIKEAVENHLQDCEKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEV
                     GERLNAEVGSKAYGSLSIVVQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRTEPLV
                     TVDNEEAFFKLAKAAFAQRRKTINNNYQNYFKDGKQHKEVILQWLEQAGIDPRRRGET
                     LSIQDFAKLYEEKKKFPQLEN"
     gene            11551..11814
                     /locus_tag="RFE25_001110"
     CDS             11551..11814
                     /locus_tag="RFE25_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDU2816194.1"
                     /translation="MPKSILDIKNSIDCHVGNRIVLKANGGRKKTIKRSGILKETYPS
                     VFIVELDQDKHNFERVSYTYTDVLTENVQVSFEEDNHHESIAH"
     gene            12124..12972
                     /locus_tag="RFE25_001111"
     CDS             12124..12972
                     /locus_tag="RFE25_001111"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDU2816195.1"
                     /translation="MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHK
                     RKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGS
                     ADAAATLRGLNRLFDIGASLEELALLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKP
                     PSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEP
                     ISVSKHPQIDKLKNNMLKSGADGALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVY
                     LVRLLG"
     gene            12986..13810
                     /gene="purR"
                     /locus_tag="RFE25_001112"
     CDS             12986..13810
                     /gene="purR"
                     /locus_tag="RFE25_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDU2816196.1"
                     /translation="MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDV
                     QIIKNTFQKEKLGTVITTAGASGGVTYKPMMSKEEATEVVNEVITLLEEKERLLPGGY
                     LFLSDLVGNPSLLNKVGKLIASIYMEEKLDAVVTIATKGISLANAVANILNLPVVVIR
                     KDNKVTEGSTVSINYVSGSSRKIETMVLSKRTLAENSNVLVVDDFMRAGGSINGVMNL
                     MNEFKAHVKGVSVLVESKEVKQRLIEDYTSLVKLSDVDEYNQEFNVEPGNSLSKFS"
     gene            13827..14207
                     /locus_tag="RFE25_001113"
     CDS             13827..14207
                     /locus_tag="RFE25_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDU2816197.1"
                     /translation="MKIINTTRLPEALGPYSHATVVNGMVYTSGQIPLNVDGKIVSAD
                     VQAQTKQVLENLKVVLEEAGSDLNSVAKATIFIKDMNDFQKINEVYGQYFNEHKPARS
                     CVEVARLPKDVKVEIELVSKIKEL"
     gene            14279..14581
                     /gene="spoVG"
                     /locus_tag="RFE25_001114"
     CDS             14279..14581
                     /gene="spoVG"
                     /locus_tag="RFE25_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDU2816198.1"
                     /translation="MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLF
                     VAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA"
     gene            14834..14965
                     /locus_tag="RFE25_001115"
     CDS             14834..14965
                     /locus_tag="RFE25_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816199.1"
                     /translation="MRLNDARIFEVRKKLFLKLQRIKNNAFYMLKEYCRLNYNNDEV"
     gene            14988..16340
                     /gene="glmU"
                     /locus_tag="RFE25_001116"
     CDS             14988..16340
                     /gene="glmU"
                     /locus_tag="RFE25_001116"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDU2816200.1"
                     /translation="MRRHAIILAAGKGTRMKSKKYKVLHEVAGKPMVEHVLESVKGSG
                     VDQVVTIVGHGAESVKGHLGERSLYSFQEKQLGTAHAVQMAKSHLEDKEGTTIVVCGD
                     TPLITKETLETLIAHHEDANAQATVLSASIQQPYGYGRIVRNASGRLERIVEEKDATQ
                     AEKDINEISSGIFAFNNKTLFEKLTQVKNDNAQGEYYLPDVLSLILNDGGIVEVYRTN
                     DVEEIMGVNDRVMLSQAEKAMQRRTNHYHMLNGVTIIDPDSTFIGPDVTIGSDTVIEP
                     GVRINGRTEIGEDVVIGQYSEINNSTIENGACIQQSVVNDASVGANTKVGPFAQLRPG
                     AQLGADVKVGNFVEIKKADLKDGAKVSHLSYIGDAVIGERTNIGCGTITVNYDGENKF
                     KTIVGKDSFVGCNVNLVAPVTIGDDVLVAAGSTITDDVPNDSLAVARARQTTKEGYRK
                     "
     gene            16487..17452
                     /locus_tag="RFE25_001117"
     CDS             16487..17452
                     /locus_tag="RFE25_001117"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDU2816201.1"
                     /translation="MLNNEYKNSSLKIFSLKGNEALAQEVADQVGIELGKCSVKRFSD
                     GEIQINIEESIRGCDVFIIQPTSYPVNLHLMELLIMIDACKRASAATINIVVPYYGYA
                     RQDRKARSREPITAKLVANLIETAGATRMIALDLHAPQIQGFFDIPIDHLMGVPILAK
                     HFKDDPNINPEECVVVSPDHGGVTRARKLADILKTPIAIIDKRRPRPNVAEVMNIVGE
                     IEGRTAIIIDDIIDTAGTITLAAQALKDKGAKEVYACCTHPVLSGPAKERIENSAIKE
                     LIVTNSIHLDEDRKPSNTKELSVAGLIAQAIIRVYERESVSVLFD"
     gene            17602..18255
                     /locus_tag="RFE25_001118"
     CDS             17602..18255
                     /locus_tag="RFE25_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HDU2816202.1"
                     /translation="MASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVD
                     EVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTV
                     EVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVK
                     VTGDFKIENDSAESVVTVVAPTEEPTEEEIEAMEGEQQTEEPEVVGESKEDEEKTEE"
     gene            18566..19138
                     /locus_tag="RFE25_001119"
     CDS             18566..19138
                     /locus_tag="RFE25_001119"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDU2816203.1"
                     /translation="MKCIVGLGNIGKRFELTRHNIGFEVVDYILEKNNFSLDKQKFKG
                     AYTIERMNGDKVLFIEPMTMMNLSGEAVAPIMDYYNVNPEDLIVLYDDLDLEQGQVRL
                     RQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMTVPDYVLQRFSNDEMVTMEK
                     VIEHAARAIEKFVETSRFDHVMNEFNGEVK"
     gene            19138..22644
                     /gene="mfd"
                     /locus_tag="RFE25_001120"
     CDS             19138..22644
                     /gene="mfd"
                     /locus_tag="RFE25_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDU2816204.1"
                     /translation="MTILTTLIKEDNHFQDLNQVFGQANTLVTGLSPSAKVTMIAEKY
                     AQSNQQLLLITNNLYQADKLETDLLQFIDAEELYKYPVQDIMTEEFSTQSPQLMSERI
                     RTLTALAQGKKGLFIVPLNGLKKWLTPVEMWQNHQMTLRVGEDIDVDQFLNKLVNMGY
                     KRESVVSHIGEFSLRGGIIDIFPLIGEPIRIELFDTEIDSIRDFDVETQRSKDNIEEV
                     DITTASDYIITEEVIRHLKEELKTAYENTRPKIDKSVRNDLKETYESFKLFESTYFDH
                     QILRRLVAFMYETPSTIIEYFQKDAIIAVDEFNRIKETEESLTVESDSFISNIIESGN
                     GFIGQSFIKYDDFETLIEGYPVTYFSLFATTMPIKLNHIIKFSCKPVQQFYGQYDIMR
                     SEFQRYVNQNYHIVVLVETETKVERMQAMLSEMHIPSITKLHRSMSSGQAVIIEGSLS
                     EGFELPDMGLVVITERELFKSKQKKQRKRTKAISNAEKIKSYQDLNVGDYIVHVHHGV
                     GRYLGVETLEVGQTHRDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKTPKLNKLGGS
                     EWKKTKAKVQQSVEDIAEELIDLYKEREMAEGYQYGEDTAEQTTFELDFPYELTPDQA
                     KSIDEIKDDMQKSRPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQ
                     HYETLIERMQDFPVEIQLMSRFRTPKEIKQTKEGLKTGFVDIVVGTHKLLSKDIQYKD
                     LGLLIVDEEQRFGVRHKERIKTLKHNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPP
                     ENRFPVQTYVLEQNMSFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANI
                     AVAHGQMTERDLEETMLSFINNEYDILVTTTIIETGVDVPNANTLIIEDADRFGLSQL
                     YQLRGRVGRSSRIGYAYFLHPANKVLTETAEDRLQAIKEFTELGSGFKIAMRDLNIRG
                     AGNLLGKQQHGFIDTVGFDLYSQMLEEAVNEKRGIKEPESEVPEVEVDLNLDAYLPTE
                     YIANEQAKIEIYKKLRKTETFDQIIDIKDELIDRFNDYPVEVARLLDIVEIKVHALHS
                     GITLIKDKGKIIGIHLSVKATENIDGEVLFKATQPLGRTMKVGVQNNAMTITLTKQNQ
                     WLDSLKFLVKCIEESMRISDEA"
     gene            22634..24160
                     /locus_tag="RFE25_001121"
     CDS             22634..24160
                     /locus_tag="RFE25_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDU2816205.1"
                     /translation="MKHKEAFNGVVVLTAALIVIKILSAVYRIPYQNILGDTGLYAYQ
                     QVYPIVALGMILSMNAIPSAITQNIGKYHSDEAYAKAVAYIQLVGILLFIAIFVFANN
                     IAHMMGDSHLTPMIQAASLSFIFIGMLGVLRGYYQSANNMTVPAISQVIEQVIRVGII
                     IVTIVIFVDRGWTIYEAGTIAILASTIGFLGSSIYLVAHRPFKFKMVNNTAKIVWKQF
                     ALSVLIFAISQLIVILWQVIDSVTIIKSLQAIRVPFDVAITEKGVYDRGASFIQMGLI
                     VTTTFSFALIPLLSDAIKMNNQVLMNRYANASLKITILISTAAGIGLINLLPLMNGVF
                     FKTNDLTLTLSVYMITVICVSLIMMDMALLQAQHAVRPIFVGMTAGLVIKFILNIILI
                     RLSGIIGASISTVVSLIIFGTIIHIAVTRKYHLHAMRRFFINVVLGMVFMSIVVQCVL
                     NIVTTHGRFTGLIELLCAAVLGIIALFFYIFRFNVLTYKELTYLPFGSKLYQIKKGRR
                     "
     gene            24160..25353
                     /locus_tag="RFE25_001122"
     CDS             24160..25353
                     /locus_tag="RFE25_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDU2816206.1"
                     /translation="MAHTITIVGLGNYGIDDLPLGIYKFLKTQDKVYARTLDHPVIES
                     LQDELTFQSFDHVYEAHDQFEDVYNDIVAQLVEAANEKDIVYAVPGHPRVAETTTVKL
                     LALAKDNTDIDVKVLGGKSFIDDVFEAVNVDPNDGFTLLDATSLQEVILNVRTHTLIT
                     QVYSAMVAANLKITLMERYPDDYPVQIVTGARSDGADNVVTCPLYELDHDENAFNNLT
                     SVFVPKIITSTYLYHDFDFATEVIDTLVDEDKGCPWDKVQTHETLKRYLLEETFELFE
                     AIDNEDDWHMIEELGDILLQVLLHTSIGKKEGYIDIKEVITSLNAKMIRRHPHIFGDA
                     NAETIDDLKEIWSKAKDAEGKQPRVKFEKVFAEHFLNLYEKTKDKSFDEASLKQWLEK
                     GESNT"
     gene            25350..25613
                     /locus_tag="RFE25_001123"
     CDS             25350..25613
                     /locus_tag="RFE25_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDU2816207.1"
                     /translation="MRLDKYLKVSRLIKRRTLAKEVSDQGRITINGNVAKAGSDVKVE
                     DVLTIRFGQKLVTVKVTALNEHASKDNAKGMYEIIEERRLEEA"
     gene            25631..26023
                     /locus_tag="RFE25_001124"
     CDS             25631..26023
                     /locus_tag="RFE25_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDU2816208.1"
                     /translation="MKNKVEHIENQYTSQENKKKQRQKMKMRVVRRRITVFAGVLLAI
                     IVVLSILLVVQKHRNDIDAQERKAKEAQFQKQQNEEIALKEKLNNLNDKDYIEKIARD
                     DYYLSNKGEVIFRLPEDKDSSSSKSSKK"
     gene            26128..26529
                     /locus_tag="RFE25_001125"
     CDS             26128..26529
                     /locus_tag="RFE25_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HDU2816209.1"
                     /translation="MSIEVGNKLKGKVTGIKKFGAFVELPEGKSGLVHISEVADNYVE
                     NVEEHLSVGDEVDVKVLSIADDGKISLSIKKAKDRPRRQHTSKPSHQKPVQKAEDFEK
                     KLSNFLKDSEDKLTSIKRQTESRRGGKGSRR"
     gene            26709..28004
                     /gene="tilS"
                     /locus_tag="RFE25_001126"
     CDS             26709..28004
                     /gene="tilS"
                     /locus_tag="RFE25_001126"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDU2816210.1"
                     /translation="MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTC
                     LHVNHGVRSASIEEARFLEAYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWF
                     DEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLA
                     VSKKEIKQFQERYHIPYFEDESNKDNKYIRNDIRNRIIPAIDENNQLKVSHLLKLKQW
                     HDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYEL
                     FNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIKK
                     PGNYFFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVPQW
                     VRDQMPIVLDKQQRIIAVGDLYQQQTIKKWIIISKNGDE"
     gene            28009..28548
                     /gene="hpt"
                     /locus_tag="RFE25_001127"
     CDS             28009..28548
                     /gene="hpt"
                     /locus_tag="RFE25_001127"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDU2816211.1"
                     /translation="MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGS
                     AMFMSDLIKRIDTHLSIDFMDVSSYHGGTESTGEVQIIKDLGSSIENKDVLIIEDILE
                     TGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYR
                     ELYRNLPYIGTLKPEVYSN"
     gene            28805..30898
                     /gene="ftsH"
                     /locus_tag="RFE25_001128"
     CDS             28805..30898
                     /gene="ftsH"
                     /locus_tag="RFE25_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDU2816212.1"
                     /translation="MQKAFRNVLVIVIIGVIIFGLFSYLNGNGNMPKQLTYNQFTEKL
                     EKGDLKTLEIQPQQNVYMVSGKTKNDEDYSSTILYNNEKELQKITDAAKKQNGVKLTI
                     KEEEKQSVFVSILSTLIPVVVIALLFIFFLSQAQGGGSGGRMMNFGKSKAKMYDNNKR
                     RVRFSDVAGADEEKQELIEIVDFLKDNKKFKEMGSRIPKGVLLVGPPGTGKTLLARAV
                     AGEAGAPFFSISGSDFVEMFVGVGASRVRDLFDNAKKNAPCIIFIDEIDAVGRQRGAG
                     VGGGHDEREQTLNQLLVEMDGFGENEGIIMIAATNRPDILDPALLRPGRFDRQIQVGR
                     PDVKGREAILHVHAKNKPLDETVDLKAISQRTPGFSGADLENLLNEASLIAVREGKKK
                     IDMRDIEEATDRVIAGPAKKSRVISKKERNIVAHHEAGHTIIGMVLDEAEVVHKVTIV
                     PRGQAGGYAMMLPKQDRFLMTEQELLDKICGLLGGRVSEDINFNEVSTGASNDFERAT
                     QIARSMVTQYGMSKKLGPLQFGHSNGQVFLGKDMQGEPNYSSQIAYEIDKEVQRIVKE
                     QYERCKQILLEHKEQLILIAETLLTEETLVAEQIQSLFYEGKLPEIDYDAAKVVKDED
                     SEFNDGKFGKSYEEIRKEQLEDGQRDESEDRKEEKDIAEDKKEADKSDEKDEPAHRQA
                     PNIEKPYDPNHPDNK"
     gene            31126..32007
                     /gene="hslO"
                     /locus_tag="RFE25_001129"
     CDS             31126..32007
                     /gene="hslO"
                     /locus_tag="RFE25_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDU2816213.1"
                     /translation="MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAM
                     GRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNE
                     QGKLDVRRAVGTNGSIIVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVG
                     LGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLN
                     EILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGN
                     KYKYTEEELNVLLESLA"
     gene            32186..33118
                     /gene="cysK"
                     /locus_tag="RFE25_001130"
     CDS             32186..33118
                     /gene="cysK"
                     /locus_tag="RFE25_001130"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDU2816214.1"
                     /translation="MAQKPVDNITQIIGGTPVVKLRNVVDDNAADVYVKLEYQNPGGS
                     VKDRIALAMIEKAEREGKIKPGDTIVEPTSGNTGIGLAFVCAAKGYKAVFTMPETMSQ
                     ERRNLLKAYGAELVLTPGSEAMKGAIKKAKELKEEHGYFEPQQFENPANPEVHELTTG
                     PELLQQFEGKTIDAFLAGVGTGGTLSGVGKVLKKEYPNIEIVAIEPEASPVLSGGEPG
                     PHKLQGLGAGFIPGTLNTEIYDSIIKVGNDTAMEMSRRVAKEEGILAGISSGAAIYAA
                     IQKAKELGKGKTVVTVLPSNGERYLSTPLYSFDD"
     gene            33334..34140
                     /gene="folP"
                     /locus_tag="RFE25_001131"
     CDS             33334..34140
                     /gene="folP"
                     /locus_tag="RFE25_001131"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDU2816215.1"
                     /translation="MTKTKIMGILNVTPDSFSDGGKFNNVETAINRVKAMIDEGADII
                     DVGGVSTRPGHEMVTLEEEELNRVLPVVEAIVGFDVKISVDTFRSEVAEACLKLGVDM
                     INDQWAGLYDHRMFQIVAKYDAEIILMHNGNGNRDEPVVEEMLTSLLAQAHQAKIAGI
                     PSNKIWLDPGIGFAKTRNEEAEVMARLDELVATEYPVLLATSRKRFTKEMMGYDTTPV
                     ERDEVTAATTAYGIMKGVRAVRVHNVELNAKLAKGIDFLKENENARHNLS"
     gene            34118..34483
                     /gene="folB"
                     /locus_tag="RFE25_001132"
     CDS             34118..34483
                     /gene="folB"
                     /locus_tag="RFE25_001132"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDU2816216.1"
                     /translation="MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLAEAGR
                     TDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKEN
                     PPIPGHYDGVGIEIVRENK"
     gene            34480..34956
                     /gene="folK"
                     /locus_tag="RFE25_001133"
     CDS             34480..34956
                     /gene="folK"
                     /locus_tag="RFE25_001133"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDU2816217.1"
                     /translation="MIQAYLGLGSNIGDRESQLNDAIKILNEYDGISVSNISPIYETA
                     PVGYTEQPNFLNLCVEIQTTLTVLQLLECCLKTEECLHRIRKERWGPRTLDVDILLYG
                     EEMIDLPKLSVPHPRMNERAFVLIPLNDIAANVVEPRSKLKVKDLVFVDDSVKRYK"
     gene            35350..35442
                     /locus_tag="RFE25_001134"
     CDS             35350..35442
                     /locus_tag="RFE25_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816218.1"
                     /translation="MVNDKVLETSKEMYVEQKCLIFYKTLKENV"
     gene            35495..36982
                     /gene="lysS"
                     /locus_tag="RFE25_001135"
     CDS             35495..36982
                     /gene="lysS"
                     /locus_tag="RFE25_001135"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDU2816219.1"
                     /translation="MSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEW
                     DQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEF
                     DLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYR
                     QRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTH
                     HNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAY
                     ADYHDIMDLTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFY
                     EVKSDEEAKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPLA
                     KKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDE
                     DYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK"
     gene            37540..37654
                     /gene="rrf"
                     /locus_tag="RFE25_001136"
     rRNA            37540..37654
                     /gene="rrf"
                     /locus_tag="RFE25_001136"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            37667..37742
                     /locus_tag="RFE25_001137"
     tRNA            37667..37742
                     /locus_tag="RFE25_001137"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37700..37702,aa:Val,seq:tac)
     gene            37759..37834
                     /locus_tag="RFE25_001138"
     tRNA            37759..37834
                     /locus_tag="RFE25_001138"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37792..37794,aa:Thr,seq:tgt)
     gene            37841..37913
                     /locus_tag="RFE25_001139"
     tRNA            37841..37913
                     /locus_tag="RFE25_001139"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37874..37876,aa:Lys,seq:ttt)
     gene            37947..38021
                     /locus_tag="RFE25_001140"
     tRNA            37947..38021
                     /locus_tag="RFE25_001140"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37979..37981,aa:Gly,seq:gcc)
     gene            38029..38117
                     /locus_tag="RFE25_001141"
     tRNA            38029..38117
                     /locus_tag="RFE25_001141"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38063..38065,aa:Leu,seq:taa)
     gene            38123..38199
                     /locus_tag="RFE25_001142"
     tRNA            38123..38199
                     /locus_tag="RFE25_001142"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38157..38159,aa:Arg,seq:acg)
     gene            38220..38293
                     /locus_tag="RFE25_001143"
     tRNA            38220..38293
                     /locus_tag="RFE25_001143"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38254..38256,aa:Pro,seq:tgg)
     gene            38317..38392
                     /locus_tag="RFE25_001144"
     tRNA            38317..38392
                     /locus_tag="RFE25_001144"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38350..38352,aa:Ala,seq:tgc)
     gene            38514..>38587
                     /locus_tag="RFE25_001145"
     rRNA            38514..>38587
                     /locus_tag="RFE25_001145"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT        13815 a         5220 c         7818 g        11734 t
ORIGIN      
        1 tcaaagaagt gttactatat aattaatact tttgaaagta actaattcca aaacagtgta
       61 aataaaggaa gcgtatatca tgaagcaacc tattttaaat aaattagaaa gtttaaatca
      121 agaagaagcg atttctttgc atgttccggg tcataaaaat atgactatcg gtcatttatc
      181 tcaattatca atgacaatgg ataaaactga aatacctgga ttagatgatt tacatcatcc
      241 tgaagaagtc attttggaaa gtatgaagca ggtggagaaa cattcagatt atgatgctta
      301 tttcttagtg aatggcacca cttcaggaat attatctgtc atccagtctt tttcacagaa
      361 aaaaggcgat atcttaatgg caagaaatgt acataaatct gtgttacatg cgctcgatat
      421 tagccaacaa gaagggcatt ttattgaaac gcatcaaagt ccgttaacga atcattataa
      481 taaagttaat ttaagccgtt tgaataatga cggtcacaaa cttgctgtgt tgacttatcc
      541 taactattac ggtgaaacat ttaatgtaga agaggttatc aaatctttgc accaattaaa
      601 tattcctgta ctcattgacg aagcacacgg cgcgcacttt ggattgcaag gatttccaga
      661 ttctacatta aattatcaag ctgactatgt tgttcaatct tttcataaaa cgttaccagc
      721 tttaacgatg ggctcggtac tttatattca taaaaatgca ccttatagag aaactattat
      781 agaatatcta agctacttcc aaacatctag tccttcgtat ttgattatgg ctagtttaga
      841 gtcagctgcc gagttctata aaacatatga tagtaccgtg ttttttgata agagagcgca
      901 attaatcgaa tgtttggaga agaagggttt tgaaatgctt caagttgatg atccgttgaa
      961 gttgctgata aaatatgaag gttttacagg tcatgatatt caaaattggt ttatgaatgc
     1021 acatatctat ttagaattag cggacgacta tcaagcatta gcgatattgc cgttatggca
     1081 tcatgatgat acgtatttat ttgatttgct tttacgtaaa attgaagata tgattttacc
     1141 gaaaaaatca gtttctaaag ttaaacaaac acaactttta acaactgaag gtaactataa
     1201 accaaaacgc tttgaatatg ttacttggtg tgatttgaaa aaggcaaaag gtaaagttct
     1261 ggcgcgacat attgtcccgt atccgccagg gattcctatt attttcaaag gagaaacaat
     1321 aactgaaaat atgatagaat tggtaaatga atatctggaa actggaatga tagttgaagg
     1381 aattaaaaat aataaaattt tagttgagga tgaataaaat gtcagctttt ataacttttg
     1441 agggcccaga aggctctgga aaaacaactg taattaatga agtttaccat agattagtaa
     1501 aagattatga tgtcattatg actagagaac caggtggtgt tcctactggt gaagaaatac
     1561 gtaaaattgt attagaaggc aatgatatgg acattagaac tgaagcaatg ttatttgctg
     1621 catctagaag agaacatctt gtattaaagg tcataccagc tttaaaagaa ggtaaggttg
     1681 tgttgtgtga tcgctatatc gatagttcat tagcttatca aggttatgct agagggattg
     1741 gcgttgaaga agtaagagca ttaaacgaat ttgcaataaa tggattatat ccagacttga
     1801 cgatttattt aaatgttagt gctgaagtag gtcgcgaacg tattattaaa aattcaagag
     1861 atcaaaatag attagatcaa gaagatttaa agtttcacga aaaagtaatt gaaggttacc
     1921 aagaaatcat tcataatgaa tcacaacggt tcaaaagcgt taatgcagat caacctcttg
     1981 aaaatgttgt tgaagacacg tatcaaacta tcatcaaata tttagaaaag atatgatata
     2041 attgttagaa gaggtgttat aaaatgaaaa tgattatagc gatcgtacaa gatcaagata
     2101 gtcaggaact tgcagatcaa cttgttaaaa ataactttag agcaacaaaa ttggcaacaa
     2161 caggtgggtt tttaagagcg ggtaatacaa cattcttatg tggtgtcaat gatgaccgtg
     2221 tagatgaaat attgtctgtg attaatcaaa cgtgtggtaa tagagaacag ttggtttcac
     2281 ctattacacc tatgggaggc agtgcggatt cgtacattcc atatccagtt gaagttgaag
     2341 ttggcggtgc tactgtattt gttatgccag ttgatgcatt ccatcaattt taattctata
     2401 atacaatcat caattagaga tacttaaaat agtgtattaa taagttatta acaattttgg
     2461 gttgcttgac tgcgactagt tcagatgcca atagatttga tttttgtggt tctaaaaata
     2521 atcacaaatc atggtcgcta ttgttgcagt aattagttgc tctttggcaa cctttttata
     2581 taaaagcaaa agggagtttg taatgaatgg atgaacagca acaattgacg aatgcatatc
     2641 attcaaataa attatcgcat gcctatttat ttgaaggtga tgatgcacaa acgatgaaac
     2701 aagttgcgat taattttgca aagcttattt tatgtcaaac agatagtcaa tgtgaaacaa
     2761 aggttagtac atataatcat ccagacttta tgtatatatc aacaactgag aatgcaatta
     2821 agaaagaaca agttgaacaa cttgtgcgtc atatgaatca acttcctata gaaagcacaa
     2881 ataaagtgta catcattgaa gactttgaaa agttaactgt tcaaggggaa aacagtatct
     2941 tgaaatttct tgaagaacca ccggacaata cgattgctat tttattgtct acaaaacctg
     3001 agcaaatttt agacacaatc cattcaaggt gtcagcatgt gtatttcaag cctattgata
     3061 aagaaaagtt tataaataga ttagttgaac aaaacatgtc taagccagta gctgaaatga
     3121 ttagtactta tactacgcaa atagataatg caatagcttt aaatgaagaa tttgatttat
     3181 tagcattaag gaaatcagtt atacgttggt gtgaattgtt gcttactaac aagccaatgg
     3241 cacttatagg tattattgat ttattgaaac aggctaaaaa taaaaaactg caatctttaa
     3301 ctattgcagc tgtgaatggt ttcttcgaag atatcataca tacaaaggta aatgtagagg
     3361 ataaacaaat atatagtgat ttaaaaaatg atattgatca atatgcgcaa aagttgtcgt
     3421 ttaatcaatt aattttgatg tttgatcaac tgacggaagc acataagaaa ttgaatcaaa
     3481 atgtaaatcc aacgcttgta tttgaacaaa tcgtaattaa gggtgtgagt tagatgccaa
     3541 atgtaatagg tgttcagttt caaaaagcgg gaaaattaga atattataca cctaatgata
     3601 tacaagtaga tatagaaggc tgggtagttg tcgaatctaa aagaggcata gagataggta
     3661 ttgttaaaaa tccattaatg gatattgctg aagaggatgt tgtgttacct cttaaaaata
     3721 ttattcgcat tgctgatgac aaagatattg ataaatttaa ttgtaatgaa cgagatgctg
     3781 aaaatgcatt aatactatgt aaagacattg taagagaaca aggtttggac atgcgtttag
     3841 tcaattgcga atatacatta gataaatcga aagttatttt taattttacg gcggatgatc
     3901 gtattgattt tagaaaatta gtaaaaatat tagcgcaaca tttaaaaaca cgtatcgagt
     3961 tgagacaaat tggtgtaagg gatgaagcca aattgcttgg cggtatcgga ccttgtggta
     4021 ggtcgttatg ttgttctaca tttttagggg attttgaacc agtatcgatt aagatggcta
     4081 aggatcaaaa tttatcatta aatccaacta aaatttctgg tgcatgtggt cgtttgatgt
     4141 gttgtttaaa atatgaaaat gactattatg aggaagtacg tgcacaatta cctgatattg
     4201 gtgaagcaat tgaaacgcct gatggtaacg ggaaagtagt tgctttaaat atattagaca
     4261 tttctatgca ggtgaagctt gagggacatg aacagccact tgaatataaa ttagaagaaa
     4321 tagaaactat gcattaagga ggcattatta catttggatc gcaatgaaat atttgaaaaa
     4381 ataatgcgtt tagaaatgaa tgtcaatcaa ctttcaaagg aaacttcaga attaaaggca
     4441 catgcagttg aattagtaga agaaaatgta gcgcttcaac ttgaaaatga taatttgaaa
     4501 aaggtgttgg gcaatgatga accaactact attgatactg cgaattcaaa accagcaaaa
     4561 gctgtgaaaa agccattacc aagtaaagat aatttggcta tattgtatgg agaaggattt
     4621 catatttgta aaggcgaatt atttggaaaa catcgacatg gtgaagattg tctgttctgt
     4681 ttagaagttt taagtgatta atcaagcaca ctcaaatagt gttataatta taaatgaata
     4741 tggtttggat aagtctgaga caatgcatgt ttcaggcttt aattgtgtat aaagttttgg
     4801 tgattgcata agagatggcg gtactaaatg ttattattaa gtgtgcacgc agtatcatta
     4861 gttataaaat gtagctgtta aaagtcaaaa atacatcgaa tgtagttagg catataatat
     4921 aaaaagagat ttcaattact caatagaaaa aggttgtctt cataggagtt aaaaatgtta
     4981 aaagagaatg aacgatttga tcaactaatc aaagaagatt ttagtattat tcaaaatgat
     5041 gatgtttttt cgttttcaac ggatgctttg ttgttagggc attttacaaa acctagaaca
     5101 aaagatattg tgttggactt atgttcaggc aatggggtga tacccttgtt attgtttgcg
     5161 aaacatccac gacatataga aggtgttgag attcaaaaaa cacttgtcga tatggcgcga
     5221 cgcacatttc aattcaatga tgttgatgaa tatttaacaa tgcatcacat ggatttgaaa
     5281 aacgttacta aagtatttaa accttcacaa tatactttag taacgtgtaa tccgccttat
     5341 tttaaagaga atcagcaaca ccaacatcaa aaagaagcac ataagatagc gagacatgag
     5401 attatgtgta cacttgaaga ttgcatgatt gcagcccgtc atttattaaa agaaggtggc
     5461 aggctaaata tggtacatcg tgcagataga ctaatggatg tcttgtttga aatgagaaaa
     5521 gtgaatattg aacctaagaa agtcgttttt atatatagta aggtagggaa atcagcacaa
     5581 acgatagtag tagaaggtcg aaaaggtgga aatcaaggtt tagaaatcat gcccccattt
     5641 tatatttata atgaagatgg taattatagc gaagaaatga aggacgtata ttatggatag
     5701 tcattttgta tatattgtaa aatgtagtga tggaagttta tatacaggat acgctaaaga
     5761 cgttaatgca cgtgttgaaa aacataaccg aggtcaagga gccaaatata cgaaagtaag
     5821 acgtccggtg catttagttt atcaagaaat gtatgagaca aagtctgaag cattgaagcg
     5881 tgaatatgaa attaaaactt ataccagaca aaagaaattg cgattaatta aggagcgata
     5941 gtatggctgt attatattta gtgggcacac caattggtaa tttagcagat attacttata
     6001 gagcagttga tgtattgaaa cgtgttgata tgattgcttg tgaagacact agagtaacta
     6061 gtaagctgtg taatcattat gatattccaa ctccattaaa gtcatatcac gaacataaca
     6121 aggataagca gactgctttt atcattgaac agttagaatt aggtcttgac gttgcgctcg
     6181 tatctgatgc tggattgccc ttaattagtg atcctggata cgaattagta gtggcagcca
     6241 gagaagctaa tattaaagta gagactgtgc ctggacctaa tgctgggctg acggctttga
     6301 tggctagtgg attaccttca tatgtatata catttttagg atttttgcca cgaaaagaga
     6361 aagaaaaaag tgctgtatta gagcaacgta tgcatgaaaa tagcacatta attatatacg
     6421 aatcaccgca tcgtgtgaca gatacattaa aaacaattgc aaagatagat gcaacacgac
     6481 aagtatcact agggcgtgaa ttaactaaga agttcgaaca aattgtaact gatgatgtaa
     6541 cacaattaca agcattgatt cagcaaggcg atgtaccatt gaaaggcgaa ttcgttatct
     6601 taattgaagg tgctaaagcg aacaatgaga tatcgtggtt tgatgattta tctatcaatg
     6661 agcatgttga tcattatatt caaacttcac agatgaaacc aaaacaagct attaaaaaag
     6721 ttgctgaaga acgacaactt aaaacgaatg aagtatataa tatttatcat caaataagtt
     6781 aatcacttta tcgattatat gaaattttaa acgattttat aaacgcaagc tgtaatttta
     6841 aatggtaagt tatcattttg cattgatact gataaaatga tgttgactat gataaaaaaa
     6901 tgatgacatc gacgtttttt aatgtaaaat aaatacattg aaagtaataa ataccttaac
     6961 attgaataag atgaaaatga gatgacgaga taaatgttcg cgtccgttga aatgcataga
     7021 aatcttagat attatttgaa gtgagacatt acgaggagga acagttatgg ctaaagaaac
     7081 attttatata acaaccccaa tatactatcc tagtgggaat ttacatatag gacatgcata
     7141 ttctacagtg gctggagatg ttattgcaag atataagaga atgcaaggat atgatgttcg
     7201 ttatttgact ggaacggatg aacacggtca aaaaattcaa gaaaaagctc aaaaagctgg
     7261 taagacagaa attgaatatt tggatgagat gattgctgga attaaacaat tgtgggctaa
     7321 gcttgaaatt tcaaatgatg attttatcag aacaactgaa gaacgtcata aacatgtcgt
     7381 tgagcaagtg tttgaacgtt tattaaagca aggtgatatc tatttaggtg aatatgaagg
     7441 ttggtattct gttccggatg aaacatacta tacagagtca caattagtag acccacaata
     7501 cgaaaacggt aaaattattg gtggcaaaag tccagattct ggacacgaag ttgaactagt
     7561 taaagaagaa agttatttct ttaatattag taaatataca gaccgtttat tagagttcta
     7621 tgaccaaaat ccagatttta tacaaccacc atcaagaaaa aatgaaatga ttaacaactt
     7681 cattaaacca ggacttgctg atttagctgt ttctcgtaca tcatttaact ggggtgtcca
     7741 tgttccgtct aatccaaaac atgttgttta tgtttggatt gatgcgttag ttaactatat
     7801 ttcagcatta ggctatttat cagatgatga gtcactattt aacaaatact ggccagcaga
     7861 tattcattta atggctaagg aaattgtgcg attccactca attatttggc ctattttatt
     7921 gatggcatta gacttaccgt tacctaaaaa agtctttgca catggttgga ttttgatgaa
     7981 agatggaaaa atgagtaaat ctaaaggtaa tgttgtagac cctaatattt taattgatcg
     8041 ctatggttta gatgctacac gttattatct aatgcgtgaa ttaccatttg gttcagatgg
     8101 cgtatttaca cctgaagcat ttgttgagcg tacaaatttc gatctagcaa atgacttagg
     8161 taacttagta aaccgtacga tttctatggt taataagtac tttgatggcg aattaccagc
     8221 gtatcaaggt ccacttcatg aattagatga agaaatggaa gctatggctt tagaaacagt
     8281 gaaaagctac actgaaagca tggaaagttt gcaattttct gtggcattat ctacggtatg
     8341 gaagtttata agtagaacga ataagtatat tgacgaaaca acgccttggg tattagctaa
     8401 ggacgatagc caaaaagata tgttaggcaa tgtaatggct cacttagttg aaaatattcg
     8461 ttatgcagct gtattattac gtccattctt aacacatgcg ccgaaagaga tttttgaaca
     8521 attgaacata aacaatcctc aatttatgga atttagtagt ttagagcaat atggtgtgct
     8581 tactgagtca attatggtta ctgggcaacc taaacctatt ttcccaagat tggatagcga
     8641 agcggaaatt gcatatatca aagaatcaat gcaaccgcct gctactgaag aggaaaaaga
     8701 agagattcct agcaaacctc aaattgatat taaagacttt gataaagttg aaattaaggc
     8761 agcaacgatt attgatgctg aacatgttaa gaagtcagat aagcttttaa aaattcaagt
     8821 agacttagat tctgaacaaa gacaaattgt atcaggaatt gccaaattct atacaccaga
     8881 tgatattatt ggtaaaaaag tagcagttgt tactaacctg aaaccagcta aattaatggg
     8941 acaaaaatct gaaggtatga tattatctgc tgaaaaagat ggtgtattaa ccttagtaag
     9001 tttaccaagt gcaattccaa atggtgcagt gattaaataa ctgtattttt aaaaattagg
     9061 agagataatt atgttaatcg atacacatgt ccatttaaat gatgagcaat acgatgatga
     9121 tttgagtgaa gtgattacac gtgctagaga agcaggtgtt gatcgtatgt ttgtagttgg
     9181 ttttaacaaa tcgacaattg aacgcgcgat gaaattaatc gatgagtatg attttttata
     9241 tggcattatc ggttggcatc cagttgacgc aattgatttt acagaagaac acctggaatg
     9301 gattgaatct ttagctcagc atccaaaagt gattggtatt ggtgaaatgg gattagatta
     9361 tcactgggat aaatctcctg cagatgttca aaaggaagtt tttagaaagc aaattgcttt
     9421 agctaagcgt ttgaagttac caattatcat tcataaccgt gaagcaactc aagactgtat
     9481 cgatatctta ttggaggagc atgctgaaga ggtaggcggg attatgcata gctttagtgg
     9541 ttctccagaa attgcagata ttgtaactaa taagctgaat ttttatattt cattaggtgg
     9601 acctgtgaca tttaaaaatg ctaaacagcc taaagaagtt gctaagcatg tgtcaatgga
     9661 gcgtttgcta gttgaaaccg atgcaccgta tctctcgcca catccgtata gagggaagcg
     9721 aaatgaaccg gcgagagtaa ctttagtagc tgaacaaatt gctgaattaa aaggcttatc
     9781 ttatgaagaa gtgtgcgaac aaacaactaa aaatgcagag aaattgttta atttaaattc
     9841 ataaagttaa aagtgagaaa gatcaccgcc ataaatgtaa acgatgctat attcgtttaa
     9901 tatgctatgg ttctttctca cttttttaaa ttaaaatatc gtacatgtgc aatacgtacg
     9961 atagagatgg ttagagcttt gaaattaaga attgtaggaa ggcgttttaa atgaaaatca
    10021 atgagtttat agttgtagaa ggacgagatg atactgagcg tgttaaacga gctgttgaat
    10081 gtgatacgat tgaaacgaat ggtagtgcca tcaacgaaca aactttagaa gtaattagaa
    10141 atgctcaaca aagtcgaggc gttattgtat taacagatcc agatttccca ggagataaaa
    10201 ttagaagtac aattactgaa catgtcaaag gtgttaaaca tgcgtatatt gatagagaaa
    10261 aagctaaaaa taaaaaaggg aaaattggtg ttgaacatgc cgacttaatt gatattaaag
    10321 aagcgttaat gcatgttagt tcaccctttg atgaagctta tgaatcaatt gataaatctg
    10381 tgctaataga gttggggtta atcgttggga aagatgcaag gcgccgtaga gaaattttaa
    10441 gtagaaaatt gcgaatcggc cattccaatg gtaagcagtt attgaaaaag ttaaatgcat
    10501 ttggttatac cgaagcggat gtaaggcaag ctttagaaga tgaatgagga agtgaaaatg
    10561 ttggataata aagatattgc aacaccatca agaacgcgag cgttgttaga taaatatggc
    10621 tttaatttta aaaaaagttt aggacagaac tttttgatag atgtgaatat cattaataat
    10681 atcattgatg caagtgatat tgatgcacaa actggggtga ttgaaattgg tccaggtatg
    10741 gggtcgttga cagaacaatt ggccagacat gctaaaagag tattggcatt tgaaattgat
    10801 caacgtttaa tacctgtatt aaatgatact ctatcacctt atgataatgt gacggtgatt
    10861 aatgaagata ttttaaaagc gaatattaaa gaagctgttg aaaatcattt acaagattgc
    10921 gaaaaaataa tggttgttgc aaacctgccg tactatatta cgacgccaat tttattaaat
    10981 ttaatgcaac aagatatacc aattgatggc tacgtggtga tgatgcaaaa agaagtgggc
    11041 gaacgcttaa atgctgaagt aggttcaaaa gcatatggtt cattatcaat tgtcgtacaa
    11101 tactatacag agactagtaa agtattaacg gtacctaaat ctgtatttat gccaccacct
    11161 aatgttgatt caatagttgt aaaactgatg cagagaactg aaccgttagt aacagtagat
    11221 aacgaggaag cattctttaa gttagcaaaa gcagcatttg cacaaagaag aaagacaatt
    11281 aacaataact atcaaaatta ttttaaagat ggtaaacaac acaaagaagt gattttacaa
    11341 tggttggaac aagcaggtat tgatccaaga cgtcgcggtg aaacgctatc tattcaagat
    11401 tttgctaaat tgtatgaaga aaagaaaaaa ttccctcaat tagaaaatta aatgattgac
    11461 aaagcaaagc actattgtta aaatttaaat tttgtttgac gaaaacgctg caaatatggt
    11521 attatgtaac ttgtagcgag gtggagcaat atgccaaaat caattttgga catcaaaaat
    11581 tctattgatt gtcatgtagg aaatcgtatt gtactgaaag ccaatggagg ccgtaagaaa
    11641 acaataaaac gttctggaat tttaaaagaa acatatccgt cagttttcat tgttgagtta
    11701 gatcaagaca aacacaactt tgagagagta tcttatacat acactgatgt gttaactgaa
    11761 aatgttcaag tttcatttga agaggataat catcacgaat caattgcaca ctaaataaga
    11821 catatagaga tgttaggcgt ttcttagtat aagaagtaaa tattatgata attatttgag
    11881 tgttgggcat tatgttcaat actcttttta tttacaaaat gtttaacact gatgtttcgc
    11941 ttatagattt ttcagtaaat ggataattgt atttataaac acaaatacaa gtaaatacta
    12001 agtaattaga tggagaaaat tactttttta ttaaaaaaac actaaaaaac aaattaaaat
    12061 gtcaaatatt aattctcttt atgttaaaat catcatatta agataacgaa aagagggcgg
    12121 aaaatgatat atgaaacggc accagccaaa attaatttta cgctcgatac actttttaaa
    12181 agaaatgatg gctatcatga gattgaaatg ataatgacaa cagttgattt aaatgatcgt
    12241 ttaacttttc ataaaagaaa agatcgaaag atagttgttg agattgaaca taattatgtg
    12301 ccttctaatc ataaaaatct cgcatatcgt gcagcgcaac tatttattga gcaatatcaa
    12361 ctaaagcaag gtgtaacaat ttctatcgat aaagaaatac ctgtttctgc tggcttagct
    12421 ggaggttcgg ctgatgcagc agcaacgtta agaggattga atcgactttt tgatataggg
    12481 gcgagtttgg aagaattggc tctactaggc agtaaaattg ggacagatat tccgttttgt
    12541 atttataata aaactgcact atgtactgga agaggagaga aaatcgagtt tttaaataaa
    12601 ccaccttcag cttgggtgat tcttgctaaa ccaaacttag gcatatcatc accagatata
    12661 tttaagttga tcaatttaga taagcgttac gacgtacata cgaaaatgtg ttatgaggcc
    12721 ttagaaaatc gagattatca acaattatgt caaagtttgt ctaatcgatt agagccaatt
    12781 tctgtttcaa aacacccaca aatcgataaa ttaaaaaata atatgttgaa aagtggtgca
    12841 gatggtgcgt taatgagtgg aagcggaccg actgtgtatg ggctagcacg aaaagaaagc
    12901 caagcaaaaa atatttataa tgcagttaac ggttgttgta atgaagtgta cttagttaga
    12961 ctattaggat agaagggttg aaaagatgag atataaacga agcgagagaa ttgtttttat
    13021 gacgcaatat ttgatgaacc atccgaataa attgattcca ttaacttttt ttgtgaaaaa
    13081 atttaaacag gcgaaatctt caataagtga agatgtccaa attataaaaa atacattcca
    13141 aaaagaaaag ttaggtacag taattactac tgctggcgca agtggtggtg ttacgtataa
    13201 accaatgatg agtaaagaag aggcgactga agttgttaat gaggtcatta ctctattaga
    13261 agagaaagaa cgtttgttac ctggcgggta tttattttta tcagatttgg taggtaatcc
    13321 atcgctacta aacaaagttg gtaagttaat tgccagtatt tacatggaag aaaaattaga
    13381 tgctgttgtt accattgcga caaaaggtat ttcattggca aatgcggttg ctaatatttt
    13441 aaatttacca gtagtagtga ttagaaaaga caacaaggtg actgaaggtt ctacagtttc
    13501 aattaattac gtttcaggat cttcaagaaa aatagagaca atggtacttt cgaagagaac
    13561 tttagcagaa aattcaaatg ttttagttgt cgatgatttt atgagggctg gtggctctat
    13621 taatggtgtt atgaatttaa tgaatgagtt taaagcccat gtaaaagggg tatcagtact
    13681 tgtagaatca aaagaagtta aacaaagatt gattgaagat tatacttcct tagtgaaatt
    13741 atctgatgta gatgaatata atcaagagtt taacgtagaa cctggcaaca gtttatctaa
    13801 gttttcataa aaggagtttt agtattatga aaatcattaa cacaacaaga ttaccggaag
    13861 cacttggacc atattcgcat gcaacagttg tgaatggtat ggtttatact tctggtcaga
    13921 ttccattgaa tgttgatggg aaaatcgtaa gcgctgatgt tcaagcacag acaaaacaag
    13981 ttttagaaaa tttaaaggtt gttttggaag aagcaggatc tgatttgaat tctgttgcga
    14041 aagcgaccat tttcattaaa gatatgaatg atttccaaaa aataaatgaa gtgtatggtc
    14101 aatattttaa tgaacacaag ccagcgcgta gttgtgtaga ggttgcgcgt ttgccaaaag
    14161 atgtgaaagt agaaattgaa ttagtaagta aaattaagga attataattt tcgattaata
    14221 tgtttaatca agcttctaaa taaaacagag agatatatac tatagggggg ctcactacat
    14281 gaaagtgaca gatgtaagac ttagaaaaat acaaacagat ggacgaatga aagcactcgt
    14341 ttccattaca ttagatgaag ctttcgtaat tcatgattta cgtgtaattg aaggaaactc
    14401 tggcttgttc gttgcaatgc caagtaaacg tacaccagat ggtgaattcc gcgacatcgc
    14461 gcatcctatt aattcagata tgagacaaga aattcaagat gcagtgatga aagtatatga
    14521 tgaaacagat gaagtagtac cagataaaaa cgctacatca gaagattcag aagaagctta
    14581 atcaatttta tatttagcga tgtaatacat ttgcaataag ttgatttgat actgtcgata
    14641 aagcataaag ctttgtcggc agttttttta gtttgtatta atgttttttt agtttgtatt
    14701 aatgtttttt tagtttgtat taatgttttt ttagtttgta ttaatgtttt tttattttta
    14761 atgaaaggct aataaatata tacgttaaca gattatgatg atatgaaaat tattgattca
    14821 ttgctgataa aaattgcgtt tgaatgatgc tcgtattttt gaagtaagaa aaaagttgtt
    14881 tttaaaatta caacgaatta aaaacaatgc cttttatatg ttgaaagagt attgcagatt
    14941 aaattataat aatgacgaag tgtaaaattt aatgggggtt aatgttcatg cgaagacacg
    15001 cgataatttt ggcagcaggt aaaggcacaa gaatgaaatc taaaaagtat aaagtgctac
    15061 acgaggttgc tgggaaacct atggtcgaac atgtattgga aagtgtgaaa ggctctggtg
    15121 tcgatcaagt tgtaaccatc gtaggacatg gtgctgaaag tgtaaaagga catttaggcg
    15181 agcgttcttt atacagtttt caagagaaac aactcggtac tgcgcatgca gtgcaaatgg
    15241 cgaaatcaca cttagaagac aaggaaggta cgacaatcgt tgtatgtggt gacacaccgc
    15301 tcatcacaaa ggaaacatta gaaacattga ttgcgcatca tgaggatgct aatgctcaag
    15361 caactgtatt atctgcatcg attcaacaac catatggata cggaagaatc gttcgaaatg
    15421 cgtcaggtcg tttagaacgc atagttgaag agaaagatgc aacgcaagct gaaaaggata
    15481 ttaatgaaat tagttcaggt atttttgcgt ttaataataa aacgttgttt gaaaaattaa
    15541 cacaagtgaa aaatgataat gcgcaaggtg aatattacct ccctgatgta ttgtcgttaa
    15601 ttttaaatga tggcggcatc gtagaagtgt atcgtaccaa tgatgttgaa gaaatcatgg
    15661 gtgtaaatga tcgtgtaatg cttagtcagg ctgagaaggc gatgcaacgt cgtacgaatc
    15721 attatcacat gctaaatggt gtgacaatca tcgatcctga cagcactttt attggtccag
    15781 acgttacaat tggtagtgat acagtcattg aaccaggcgt acgaattaat ggtcgtacag
    15841 aaattggcga agatgttgtt attggtcagt actctgaaat taacaatagt acgattgaaa
    15901 atggtgcatg tattcaacag tctgttgtta atgatgctag cgtaggagct aatactaagg
    15961 tcggaccgtt tgcgcaattg agaccaggcg cgcaattagg tgcagatgtt aaggttggaa
    16021 attttgtaga aattaaaaaa gcagatctta aagatggtgc caaggtttca catttaagtt
    16081 atattggcga tgctgtaatt ggcgaacgta ctaatattgg ttgcggaacg attacagtta
    16141 actatgatgg tgaaaataaa tttaaaacta tcgtcggcaa agattcattt gtaggttgca
    16201 atgttaattt agtagcacct gtaacaattg gtgatgatgt attggtggca gctggttcca
    16261 caatcacaga tgacgtacca aatgacagtt tagctgtggc aagagcaaga caaacaacaa
    16321 aagaaggata taggaaataa tcatttacgt atttaaaatg gctaggataa aaggataatc
    16381 ctatgtaata ttaatgtaat ctttatgatt taatgattcg catagtaatg gagttacatt
    16441 ttatatataa tagtaattgc gtaagtaaat aattggagga ctataaatgt taaataatga
    16501 atataagaat tcgtcattaa agattttttc attgaaagga aacgaagcat tagcgcaaga
    16561 agttgctgac caagtaggaa ttgaactagg taaatgttca gttaaacgtt ttagtgatgg
    16621 agaaattcaa attaatatcg aagagagtat tcgtggttgt gacgtattta ttattcaacc
    16681 aacatcatat cctgtgaatc tacatttaat ggaattatta attatgattg atgcttgtaa
    16741 acgtgcttct gcagcaacaa tcaatattgt agtgccatat tatggatatg caagacaaga
    16801 tagaaaagcc cgtagccgtg agccaatcac tgctaaatta gttgcaaact taatcgaaac
    16861 agctggcgca actcgtatga ttgcgttaga cttacatgca ccacaaattc aaggattctt
    16921 tgatattcca attgaccact taatgggtgt gccaattctt gctaaacatt tcaaagatga
    16981 tccgaatatt aacccagaag aatgtgtcgt tgtttcacca gaccatggcg gtgttacacg
    17041 tgcacgtaaa ttagctgaca ttttaaaaac tccaattgca attatagata aacgtcgtcc
    17101 tagaccaaat gttgctgaag tgatgaacat tgttggtgag attgaaggac gtacggcaat
    17161 tattattgac gatattattg atacagcagg tacaatcact ttagctgcac aagcattaaa
    17221 agataaaggt gctaaagaag tatatgcttg ttgtacacac cctgttttat caggaccggc
    17281 taaagaacgt atcgaaaatt ctgctataaa agaattaatc gtaacaaact caattcattt
    17341 agatgaagat cgcaaaccat ctaacactaa agaattatct gttgctggtt taatcgcaca
    17401 agctatcatt cgtgtatacg aaagagaatc agttagcgta ttatttgact aatatttaaa
    17461 aggcgtttga cgaacatatt ccaaacgtgt ataatagttt cgttcgtgat tatacgaata
    17521 aataaacact tgcaagcaac gatgatgttg atgggtaagt gaggtgctcg ttttgagcaa
    17581 aaatgaaagg tggaaatgag aatggcttca ttaaagtcaa tcatccgtca aggtaaacaa
    17641 acacgttcag atcttaaaca attaagaaaa tctggtaaag taccagcagt agtatacggt
    17701 tacggtacta aaaacgtgtc agttaaagtt gatgaagtag aattcatcaa agttatccgt
    17761 gaagtaggtc gtaacggtgt tatcgaatta ggcgttggtt ctaaaactat caaagttatg
    17821 gttgcagact accaattcga tccacttaaa aaccaaatta ctcacattga cttcttagca
    17881 atcaatatga gtgaagaacg tactgttgaa gtaccagttc aattagttgg tgaagcagta
    17941 ggcgctaaag aaggcggcgt agttgaacaa ccattattca acttagaagt aactgctact
    18001 ccagacaata ttccagaagc aatcgaagta gacattactg aattaaacat taacgacagt
    18061 ttaactgttg ctgatgttaa agtaactggc gacttcaaaa tcgaaaacga ttcagctgaa
    18121 tcagttgtaa cagtagttgc tccaactgaa gaaccaactg aagaagaaat cgaagctatg
    18181 gaaggcgaac aacaaactga agaaccagaa gttgttggcg aaagcaaaga agacgaagaa
    18241 aaaactgaag agtaatttta atctgttaca ttaaagtttt tatactttgt ttaacaagca
    18301 ctgtgcttat tttaatataa gcatggtgct ttttgtgtta ttataaagct taattaaact
    18361 ttattacttt gtactaaagt ttaattaatt ttagtgagta aaagatatta aactcaacaa
    18421 tgatacatca taaaaatttt aatgtactcg attttaaaat acatacttac taagctaaag
    18481 aataatgata attgatggca atggcggaaa atagatgttg tcattataat aataaatgaa
    18541 acaattatgt tggaggtaaa cacgcatgaa atgtattgta ggtctaggta atataggtaa
    18601 acgttttgaa cttacaagac ataatatcgg ctttgaagtc gttgattata ttttagagaa
    18661 aaataatttt tcattagata aacaaaagtt taaaggtgca tatacaattg aacgaatgaa
    18721 cggagataaa gtgttattta tcgaaccaat gacaatgatg aatttgtcag gagaagcagt
    18781 tgcaccgatt atggattatt acaatgttaa tccagaagat ttaattgtct tatatgatga
    18841 tttagattta gaacaaggac aagttcgctt aagacaaaaa ggaagtgcgg gcggtcacaa
    18901 tggtatgaaa tcaattatta aaatgcttgg tacagaccaa tttaaacgta ttcgtattgg
    18961 tgtgggaaga ccaacgaatg gtatgacggt acctgattat gttttacaac gcttttcaaa
    19021 tgatgaaatg gtaacgatgg aaaaagttat cgaacacgca gcacgcgcaa ttgaaaagtt
    19081 tgttgaaaca tcacgatttg accatgttat gaatgaattt aatggtgaag tgaaataatg
    19141 acaatattga caacgcttat aaaagaagat aatcattttc aagaccttaa tcaggtattt
    19201 ggacaagcaa acacactagt aactggtctt tccccgtcag ctaaagtgac gatgattgct
    19261 gaaaaatatg cacaaagtaa tcaacagtta ttattaatta ccaataattt ataccaagca
    19321 gataaattag aaacagattt acttcaattt atagatgctg aagaattgta taagtatcct
    19381 gtgcaagata ttatgaccga agagttttca acacaaagcc ctcaactgat gagtgaacgt
    19441 attagaactt taactgcgtt agctcaaggt aagaaagggt tatttatcgt tcctttaaat
    19501 ggtttgaaaa agtggttaac tcctgttgaa atgtggcaaa atcaccaaat gacattgcgt
    19561 gttggtgagg atatcgatgt ggaccaattt cttaacaaat tagttaatat ggggtacaaa
    19621 cgggaatccg tggtatcgca tattggtgaa ttctcattgc gaggaggtat tatcgatatc
    19681 tttccgctaa ttggggaacc aatcagaatt gagctatttg ataccgaaat tgattctatt
    19741 cgcgattttg atgttgaaac gcagcgttcc aaagataata ttgaagaagt cgatatcaca
    19801 actgcaagtg attatatcat tactgaagaa gtgattagac atcttaaaga agagttgaaa
    19861 actgcatatg aaaatacaag acccaaaata gataaatcag tgcgcaatga tctgaaagaa
    19921 acgtatgaaa gctttaaatt attcgaaagt acatactttg atcatcaaat actacgtcgt
    19981 ttagtagcgt ttatgtatga aacaccttcg acaattattg agtatttcca aaaagatgca
    20041 atcattgcag ttgatgaatt taatcgtatt aaagaaactg aagaaagttt aacagtagag
    20101 tctgattcgt ttattagcaa tattattgaa agtggtaatg gatttatagg acaaagtttt
    20161 ataaaatatg atgattttga aacattgatt gaaggctatc ctgtcactta tttttcatta
    20221 ttcgctacaa caatgccgat aaaactaaat catattatta aattttcatg taaacctgtc
    20281 caacaatttt atgggcaata tgacattatg cgttctgaat ttcaacgata tgtcaatcaa
    20341 aattatcata tcgtggtttt ggtcgaaact gaaactaaag ttgaacgtat gcaagcgatg
    20401 ttaagtgaaa tgcatattcc atcaataaca aaattgcatc gctcaatgtc atcggggcaa
    20461 gcagtgatta ttgaaggcag tttatctgaa ggatttgaac tacctgatat gggattagtt
    20521 gtcattactg agcgtgagct ttttaaatca aaacagaaaa agcaacgaaa acgtacgaaa
    20581 gctatctcaa atgctgaaaa aattaagtct taccaagatt taaatgtggg agattatatt
    20641 gttcatgtgc atcatggtgt tggtagatat ttaggtgttg agacgctcga agtggggcaa
    20701 acgcatcgtg attatattaa attgcaatat aaaggtacgg atcaactatt tgttccagta
    20761 gatcaaatgg atcaagttca aaaatatgta gcttcggaag ataagacgcc aaaattaaat
    20821 aaactcggtg gcagtgaatg gaaaaaaaca aaagcaaaag ttcaacaaag tgttgaagat
    20881 attgctgaag agttgattga tttatataaa gaaagagaaa tggcagaagg ttatcaatat
    20941 ggggaagaca cagctgagca aacaacattt gaattagatt ttccatatga acttacgcct
    21001 gaccaagcta aatctatcga tgaaattaaa gatgacatgc aaaaatcgcg tccaatggat
    21061 cgcttgctat gtggtgatgt tggttatggt aaaactgaag ttgcagtgag agcagcattc
    21121 aaagctgtaa tggaaggaaa gcaagttgca tttttagttc ctacaactat tttagctcag
    21181 caacattatg agacgttaat tgagcgtatg caagattttc ctgttgaaat tcaattaatg
    21241 agtcgtttta gaacgccgaa agagataaaa caaactaagg aaggacttaa aactgggttt
    21301 gttgacatag ttgttggtac acacaaatta cttagtaaag atatacagta taaagattta
    21361 gggctgttga ttgtagatga agaacaacga tttggtgtac gccataaaga gcgtattaaa
    21421 acattaaaac ataatgtaga tgtactaaca ttgactgcaa ccccaatacc tagaacattg
    21481 catatgagta tgctaggtgt gcgcgatttg tcagtgattg aaacgccgcc agaaaatcgt
    21541 ttcccagttc aaacatatgt attagaacag aacatgagtt ttatcaaaga agctttagaa
    21601 agagaactat cccgtgatgg ccaagtgttt tatctttata ataaagtgca atccatttat
    21661 gaaaaacgag aacaactcca gatgttaatg ccagatgcta acattgcagt tgctcatgga
    21721 caaatgacag agcgcgattt agaagaaacg atgttaagtt ttatcaataa tgaatatgat
    21781 attttagtaa cgacgacgat tattgaaaca ggtgtcgatg tcccaaatgc aaatactttg
    21841 atcattgaag atgcagatcg ctttggattg agtcagttgt atcaattaag aggtcgtgtt
    21901 ggtcgttcaa gtcgtattgg ttatgcatac ttcttacatc cagcaaataa ggtactaact
    21961 gagactgcag aagatcgatt acaagcgatt aaagaattta cggagttagg ctcaggattt
    22021 aagattgcga tgcgtgattt gaacattcgt ggtgctggta atttgttagg taaacaacag
    22081 cacggcttta ttgatacagt tggatttgat ttgtacagtc aaatgttaga agaagctgta
    22141 aatgaaaaac gtggtattaa ggaaccagaa tctgaggtgc cagaagtcga agttgattta
    22201 aacttggatg catatttgcc aacagaatat attgcaaatg aacaagctaa aattgaaatt
    22261 tataaaaagc tacgaaaaac tgaaacattt gatcaaatta tcgacattaa agatgaatta
    22321 attgatcgtt ttaatgatta tcctgttgaa gtagcacgtt tgcttgatat agtggaaata
    22381 aaagtacacg cattacattc aggtatcacg ttgattaaag ataaagggaa aataattggt
    22441 attcatttat ctgtaaaagc cactgaaaat attgatggcg aagtgctgtt caaagcaaca
    22501 caacctttag gtagaacaat gaaggttggt gttcaaaata atgcaatgac aattacttta
    22561 acgaaacaaa atcaatggct tgatagtttg aagtttttag ttaagtgcat tgaagaaagc
    22621 atgagaatca gtgatgaagc ataaagaagc atttaatggc gttgtcgtgt taactgctgc
    22681 attaattgtc attaaaattc tgagtgctgt atatcgaatt ccatatcaaa atatattagg
    22741 tgatacaggt ttgtatgcat atcaacaagt gtatccaatt gtagcattag gaatgatatt
    22801 atcgatgaat gccattccta gtgcaattac acaaaatata gggaagtatc atagtgacga
    22861 agcatatgca aaagcggtcg cttatataca attagttggt atattattat ttattgctat
    22921 ttttgtgttt gcgaacaata ttgcacatat gatgggtgat agccatttaa caccaatgat
    22981 tcaagcagca agtttaagct ttatatttat aggtatgctt ggcgtgttaa gaggttatta
    23041 tcaatctgca aataatatga cagttccggc tatttcccag gttatagaac aagttatacg
    23101 agtaggtatt atcattgtta ctattgttat ttttgtagac agaggttgga cgatatatga
    23161 agcgggaaca attgctattt tagcatcaac gataggtttt ttaggttctt caatttattt
    23221 agtagcgcac cgacctttta agtttaaaat ggtaaataac actgcaaaga ttgtttggaa
    23281 acagttcgca ctttcggttt tgattttcgc tatcagtcaa ttaatcgtaa ttttatggca
    23341 agtgattgat agtgttacta ttattaagtc acttcaagcg atacgcgtgc cattcgatgt
    23401 tgccataact gaaaaaggag tctatgaccg tggtgcatca tttattcaga tgggattgat
    23461 tgtaactaca acatttagtt ttgcgctcat tcctctgtta agtgacgcaa tcaaaatgaa
    23521 taatcaggta cttatgaatc gttatgcaaa tgcgtcatta aagattacga ttttaataag
    23581 tacagcagcg ggaataggat taattaattt attgccttta atgaacggtg tgttttttaa
    23641 gacgaatgat ttaaccttaa cgttaagtgt ttatatgatt acggtcattt gtgtatcgtt
    23701 aattatgatg gatatggctt tattacaagc gcaacatgct gtgagaccta tttttgttgg
    23761 tatgacggca ggattggtta ttaaatttat acttaatatc attttgattc gtttaagtgg
    23821 cattattggt gcgagcatta gtactgttgt atcattaatt atattcggta cgattatcca
    23881 tattgctgtc acgagaaaat accacttaca tgcgatgaga cgatttttta tcaatgttgt
    23941 tttaggtatg gtatttatgt cgattgttgt tcaatgcgtg ttaaacatag tgacaacaca
    24001 cggtagattc actggactca ttgaattatt atgtgcagca gtattaggta tcattgcatt
    24061 gtttttctat atttttagat ttaatgtttt gacatataaa gagttaactt atttaccatt
    24121 tggttcaaag ttgtatcaaa ttaagaaagg aagacgttga tggcacatac cattacgatt
    24181 gttggcttag gaaactatgg cattgatgat ttgccgctag ggatatataa atttttaaag
    24241 acacaagata aagtttatgc aagaacgtta gatcatccag ttatagaatc attgcaagat
    24301 gaattaacat ttcagagttt tgaccatgtt tatgaagcac atgaccaatt tgaagatgtc
    24361 tataacgata ttgtggcgca attggttgaa gctgctaatg aaaaagatat tgtctatgcg
    24421 gttccgggtc atcctagagt tgctgagaca actacagtga aattactggc tttagcaaag
    24481 gacaatactg atatagatgt gaaagtttta ggtggtaaaa gctttattga tgatgtgttt
    24541 gaagcagtta atgtagatcc aaatgatggc ttcacactgt tagatgcgac atcattacaa
    24601 gaagtaatac ttaatgttag aacgcataca ttgattacgc aagtttatag tgcaatggtt
    24661 gctgctaatt tgaaaatcac tttaatggaa cgatatcctg atgattaccc tgttcaaatt
    24721 gtcactggtg cacgaagcga tggtgcggat aacgttgtga catgcccatt atatgaattg
    24781 gatcatgatg aaaatgcatt caataatttg acgagtgtat tcgtaccaaa aatcataaca
    24841 tcgacatatt tgtatcatga ctttgatttt gcaacggaag tgattgatac tttagttgat
    24901 gaagataaag gttgtccatg ggataaagtg caaacgcatg aaacgcttaa gcgttattta
    24961 cttgaagaaa catttgaatt gttcgaagct attgacaatg aagatgattg gcatatgatt
    25021 gaagaactag gagatatttt attacaagtg ttattgcata ctagtattgg taaaaaagaa
    25081 gggtatatcg acattaaaga agtgattaca agtcttaatg ctaaaatgat tcgtagacac
    25141 ccacacatat ttggtgatgc caatgctgaa actatcgatg acttaaaaga aatttggtct
    25201 aaggcgaaag atgctgaagg taaacagcca agagttaaat ttgaaaaagt atttgcagag
    25261 cattttttaa atttatatga gaagacgaag gataagtcat ttgatgaggc ctcgttaaag
    25321 cagtggctag aaaaagggga gagtaataca tgagattaga taaatattta aaagtatcac
    25381 ggttaataaa gcgacgtacg ctagcaaaag aagtaagtga tcaaggtaga attacaataa
    25441 atggtaatgt tgctaaagct ggatcggatg ttaaagttga agatgtgctg acgattcgct
    25501 ttggtcaaaa attagtaaca gttaaagtaa ctgcattaaa tgaacatgca tctaaagata
    25561 acgcgaaggg catgtatgaa atcattgaag agcgtcgact tgaagaagcg taaattggag
    25621 gtgacaagca atgaaaaata aagtagaaca tatagaaaat cagtacacgt cgcaagagaa
    25681 caagaaaaaa caacgtcaaa aaatgaaaat gcgtgttgtt cgtaggcgta ttacagtatt
    25741 tgcgggcgta ttacttgcga taattgttgt tttatcaatc ttgcttgttg tccaaaaaca
    25801 tcgcaatgat attgatgcac aggagcgaaa agcgaaagaa gcacagtttc aaaagcaaca
    25861 aaatgaagaa attgcgttaa aagaaaagtt gaataatctg aatgacaaag attacattga
    25921 aaaaattgcg cgtgatgatt attacttaag caacaaaggt gaagtgattt ttaggttgcc
    25981 agaagacaaa gattcgtcta gctcaaaatc ttcgaaaaaa taaatccaaa ttgattcaaa
    26041 attatccgag tatagacatt gtgaaaaaat ccaaacaagg atataataag ggaaaatcga
    26101 atcaaatcgg gaggatttat ttaacatatg tcaatcgaag ttggaaataa gcttaaaggt
    26161 aaagtcactg gtattaaaaa gtttggtgca ttcgtagaat tacctgaagg aaaaagtggt
    26221 ttagttcaca ttagtgaagt cgcagataat tatgttgaaa acgtagaaga gcacctttct
    26281 gttggtgatg aagtagacgt gaaagtatta tctattgctg atgatggaaa aattagtctt
    26341 tcaattaaga aagctaaaga ccgtccacgt agacaacata cgagtaaacc aagtcatcaa
    26401 aaaccagtgc aaaaagccga agattttgaa aagaaattaa gcaatttctt aaaagatagt
    26461 gaagataaat taacttcaat caaacgtcaa acagaatcta gacgcggtgg caaaggttct
    26521 agacgttaat taaaataaat aaagactgtt tcgataagga atatatttag aatgatgcgt
    26581 atcgaataat cgattgcagc gttagacaat ctaagactgt ttcttaaata aggagcagtc
    26641 tcttttattt gtaatgatat aactaagact tataccattt ttgaaaattg taaaagtgag
    26701 gtgatgttat gcagttaaat agtaatggtt ggcatgttga tgaccatatt gttgtcgctg
    26761 tttctacagg tattgatagt atgtgtttat tgtatcaact actaaatgat tataaagata
    26821 gttatagaaa actaacatgc ttacatgtca atcatggcgt taggtcagct tcaattgagg
    26881 aagccagatt tttagaagca tactgcgaac gtcatcacat tgatttacat atcaaaaagt
    26941 tagatttgtc gcatagtctc gaccgaaata acagcattca gaatgaagct cgaattaaac
    27001 gttacgaatg gtttgatgaa atgatgaatg tattagaagc ggatgtattg ctaacggcgc
    27061 atcatttgga cgatcaatta gaaactatta tgtatcgtat ttttaatggg aaatcaacgc
    27121 gtaataaact aggatttgat gagttatcga agcgaaaagg ttatcagatt tatcgaccac
    27181 ttttagctgt ctctaaaaaa gaaataaaac aattccaaga gagatatcat attccatatt
    27241 ttgaagatga atctaataaa gataacaaat atattagaaa tgatattcgt aatagaatta
    27301 ttccagctat tgatgaaaat aatcaactta aagtatcgca tttattaaaa ttaaaacaat
    27361 ggcatgatga acaatatgat attttgcaat attcagctaa acaatttatt caagaatttg
    27421 tgaagtttga tgaacagtca aaatatttag aggtttctag acaagctttt aataacttac
    27481 caaactcatt aaagatggtt gtgttggact gcctattatc aaagtattat gagttgttta
    27541 atattagtgc taaaacatac gaagagtggt ttaaacaatt tagtagtaag aaagcacaat
    27601 tcagtattaa tctcacggat aaatggataa ttcaaatcgc atatggtaaa ttaataataa
    27661 tggctaaaaa taatggcgat acatatttta gagttcaaac aattaaaaag ccaggtaatt
    27721 atttttttaa caaatatcga ttagagatac attctaattt accaaaatgt ttatttccgc
    27781 ttacagtgag aacacgacaa agtggcgata catttaaact gaatgggcgc gatggttata
    27841 agaaagtgaa tcgcctgttt atagattgta aagtgccaca gtgggttcgg gatcaaatgc
    27901 caatcgtatt ggataaacaa cagcgcatta ttgcggtagg agatttatat caacaacaaa
    27961 caataaaaaa atggattata attagtaaaa atggagatga atagcgttat gcataatgat
    28021 ttgaaagaag tattgttaac tgaagaagat attcaaaata tctgtaagga attgggagca
    28081 caattaacaa aggattatca aggtaaacca ttagtatgcg tgggtatctt aaaaggctca
    28141 gcaatgttta tgtcagattt aattaaacga attgataccc atttatcaat tgatttcatg
    28201 gatgtttcta gttatcacgg aggcactgag tcaactggtg aagttcaaat cattaaagat
    28261 ttaggttctt ctattgaaaa taaagacgta ttaattattg aagatatctt agagactggt
    28321 actacactta agtcaattac tgaattatta caatctagaa aagttaattc attagaaata
    28381 gttactttat tagataaacc aaaccgtcgt aaagcggaca ttgaagctaa gtatgtaggt
    28441 aaaaaaatac cagatgaatt tgttgttggt tacggtttag attatcgtga attataccga
    28501 aacttaccat atatcggtac gttaaaacct gaagtgtatt caaattaatt ttttaatcaa
    28561 tttcagttat tattactatg cgtttgagaa ataatagtgt agactcaaaa atatgaaaaa
    28621 tgtatttcat atatatttaa ttttagacaa gacatatgtc ttgaaaagtt gaaaaatata
    28681 gagattgata aaactaatac gggtgtgaat gacattgatg ttaagctcaa ttactagctt
    28741 ataaaacatg tcatatgtta caatttttgt tagttttatt atgggaagta ggaggaaatg
    28801 acgcatgcag aaagcttttc gcaatgtgct agttatcgta ataataggcg ttattatttt
    28861 tggtctattt tcatatttaa acggtaatgg aaatatgccg aaacagctta catataatca
    28921 atttactgag aagttggaaa aaggtgacct taaaacttta gaaatccaac cacaacaaaa
    28981 tgtctatatg gtaagtggta aaacgaaaaa tgatgaagac tattcatcaa ctattttata
    29041 taacaacgaa aaagaattac aaaaaattac tgatgctgct aaaaagcaaa acggtgtaaa
    29101 attaacgatt aaagaagaag aaaaacaaag tgtctttgtg agtatacttt caacattaat
    29161 tccagttgta gtcatagcgt tattatttat tttcttccta agccaagcac aaggtggcgg
    29221 tagtggcggt cgtatgatga actttggtaa atctaaagca aaaatgtacg ataataataa
    29281 acgtcgtgtt cgtttctctg atgtagcagg ggcagatgaa gaaaaacaag aattaattga
    29341 aattgttgat ttcttgaaag ataataaaaa attcaaagaa atgggatcta ggattcctaa
    29401 aggtgtctta cttgttggac ctccaggtac tggtaaaaca ttacttgcta gagcggttgc
    29461 aggtgaagct ggcgcaccat tcttctctat tagtggttca gactttgtag agatgtttgt
    29521 tggtgttggt gcgagccgtg ttcgtgactt attcgataat gctaagaaaa acgcgccttg
    29581 tatcatcttt atcgatgaga ttgatgctgt tggtcgtcaa cgtggtgcag gtgttggtgg
    29641 cggtcatgat gaacgtgaac aaaccctaaa ccaattatta gttgaaatgg atggtttcgg
    29701 tgaaaatgaa ggtatcatta tgatagctgc tacaaaccgt cctgatatcc ttgacccagc
    29761 cttattacgt ccaggtcgtt ttgatagaca aattcaagtt ggtcgtccag atgtgaaagg
    29821 ccgtgaagca attcttcatg ttcatgctaa aaacaaacca cttgatgaaa cggttgattt
    29881 aaaagcaatt tcacaacgta cacctggttt ctcaggtgct gatttagaga acttattaaa
    29941 tgaagcatct ttaattgctg tacgtgaagg taaaaagaaa attgacatga gagatatcga
    30001 agaggcaacg gatagagtta tagccggacc tgctaagaaa tctcgagtta tttctaagaa
    30061 agaacgtaat attgttgctc atcacgaagc tggtcataca attatcggta tggtacttga
    30121 tgaggcagaa gtagtgcata aagttactat tgttccacgt ggacaagcag gtggttatgc
    30181 aatgatgcta cctaaacaag atcgtttctt aatgactgaa caagagttat tagataaaat
    30241 ctgtggttta cttggtggac gtgtatcaga agatattaac tttaacgaag tatcaacagg
    30301 tgcttcaaat gacttcgaac gtgcaacaca aatcgcacgc tcaatggtta cgcaatatgg
    30361 tatgagtaaa aaattaggac cattacagtt cggtcatagc aatggtcaag tattcttagg
    30421 taaagatatg caaggtgagc ctaattattc aagccaaatc gcatatgaaa ttgataaaga
    30481 agttcaacga atcgttaaag aacaatacga acgttgtaaa caaattttat tagagcacaa
    30541 agaacaatta attttaattg ctgaaacatt attaacagaa gaaacattag ttgctgaaca
    30601 aattcaatca ttattctacg aaggtaaatt acctgaaatt gattatgatg cagctaaagt
    30661 tgttaaagat gaagattctg aatttaatga tggtaaattc ggtaaatctt atgaagagat
    30721 tcgtaaagag caattagaag atggacaacg tgacgaaagt gaagatcgta aagaagaaaa
    30781 agatattgct gaggataaaa aagaagctga taaatctgat gaaaaagatg aaccagcaca
    30841 tcgacaagcc ccaaatatcg aaaaacctta cgatccaaat cacccagaca ataaataatc
    30901 gattatattc agtacctctt tctatgataa agttatagaa agaggtactt ttatcgtttt
    30961 taaaaatacg tattagattt taagtcattg aattgttata gcagaaaata attgtaaaac
    31021 aagttacttc attatttaga atgatgggtg tagaataagt acaattgttg cattttatga
    31081 agtaaagtaa ttttaaaata tagagtaata gaggagattg aaataatgac acacgattat
    31141 attgttaaag cattagcatt tgatggggag attagggctt atgctgcttt gacaactgaa
    31201 actgttcaag aagcacaaac gagacattat acatggccga cagcatctgc tgcaatggga
    31261 agaacaatga cagcaacagc tatgatgggc gcaatgttga aaggtgatca aaaattaact
    31321 gtcactgtag atggccaagg acctattgga cgaattattg ccgatgcaaa tgctaaaggc
    31381 gaggtgcgtg cttatgtaga ccatccacaa actcattttc cattaaatga gcaaggtaaa
    31441 cttgatgtaa gacgagcagt agggacaaat ggatctatta tagttgttaa agacgttgga
    31501 atgaaagact atttctctgg agcaagtcca attgtttcag gagaacttgg tgaagatttt
    31561 acttattatt atgctacaag tgaacaaaca ccttcatcgg taggtcttgg tgtattggta
    31621 aatcctgata atacgattaa agcagcagga ggatttatca ttcaagttat gccaggtgcc
    31681 aaagatgaaa caatttcaaa attagaaaaa gcaattagtg aaatgacacc agtttctaaa
    31741 ttaattgaac aaggattaac gccagaagga ttactaaacg aaatcttagg tgaagaccat
    31801 gtgcaaattt tagagaaaat gcctgttcaa tttgaatgta attgtagtca tgagaaattt
    31861 ttaaatgcta ttaaaggatt gggcgaggct gagattcaaa atatgattaa agaagatcat
    31921 ggtgctgaag cagtatgtca tttctgtgga aataaatata aatatactga agaagaatta
    31981 aacgtgttgc tagaaagttt agcgtaattt aatttaaatc aatacgctaa aatgtttatt
    32041 tttagcggtt tagtgaaatg tagaactaaa tagttgtata atccttagtg attttgtttg
    32101 ctttctagaa tttatttgat aaaataattc tatatccgat aaataaacta agatttcaac
    32161 aactaactaa aaaggagtgt tcttaatggc acaaaaacca gtagataata ttactcaaat
    32221 tattggcggt acaccggtag tcaaattgag aaatgtagta gatgacaatg cagcagatgt
    32281 ttatgtaaaa ttggaatatc aaaatccagg tggttctgta aaggatagaa ttgctttagc
    32341 aatgattgaa aaagcagagc gagaaggcaa aattaaacct ggcgacacaa ttgtagaacc
    32401 aacaagtggt aatacaggta tcggtttagc atttgtatgt gctgctaaag gatataaagc
    32461 agtatttact atgcccgaaa caatgagcca agagcgtcgt aatttattaa aagcatacgg
    32521 tgcggaatta gttttaacgc ctggatcaga agcgatgaaa ggtgcaatta aaaaagctaa
    32581 agaattaaaa gaagaacatg gttacttcga gccacaacaa tttgaaaacc ctgcgaaccc
    32641 tgaagttcat gagttaacta caggtcctga gttattacaa caatttgaag ggaaaactat
    32701 cgatgcgttc ctagctggtg ttggtactgg tggtacgtta tctggtgtag gtaaagttct
    32761 gaaaaaagaa taccctaaca tcgaaattgt tgctatagag cctgaggctt ctccagtatt
    32821 gagcggtggt gagccaggtc cacataaatt acaaggttta ggtgctggat ttattccagg
    32881 cactttgaat acagaaatct atgacagtat tattaaagta ggaaatgata cagcgatgga
    32941 aatgtctcgt cgagttgcta aagaggaagg tattttagca ggtatttcat caggtgctgc
    33001 gatttatgct gccattcaaa aagcaaaaga attaggaaaa ggtaaaacag tagtaacagt
    33061 attgccgagt aatggtgaac gctacttatc aacaccttta tattcattcg atgactaatt
    33121 aatgtcattt aaaagagtga gttatctttt tgagataact tgctcttttt ttctaccatg
    33181 tataatttta aaaatatgag cgttaaatta aacatttttc tgataaaaac atccagtgaa
    33241 tgataagata ataaacgtac atattaataa ctagtaaatc gcaggagtaa attttattag
    33301 agttaaacaa tacataatta aagggtggtt aacatgacta aaacaaaaat tatgggcata
    33361 ttaaacgtca cacctgattc attctcagat ggtggaaaat ttaataatgt tgaaacagct
    33421 ataaatagag tgaaagccat gatagatgaa ggtgctgaca ttatagatgt tggaggtgtt
    33481 tcaacgagac ccggtcatga aatggttaca ttagaagaag aagagctgaa cagagtatta
    33541 cctgttgttg aagctattgt cggttttgat gtaaaaattt cagtcgatac atttcgaagt
    33601 gaggttgctg aagcatgttt aaaattaggc gttgatatga ttaatgatca atgggcgggt
    33661 ctgtatgatc atcgtatgtt ccaaattgta gctaaatatg acgcggaaat tattttaatg
    33721 cataatggaa atggtaatcg tgatgaaccg gttgtcgaag aaatgttaac atctttgtta
    33781 gcacaagcac atcaagctaa aatagctggt ataccttcaa ataaaatttg gctagatcca
    33841 ggtataggtt tcgctaaaac tagaaatgaa gaagccgaag ttatggcaag actggatgaa
    33901 cttgttgcaa cagaatatcc agttttatta gcgacaagcc ggaaacgttt cactaaagag
    33961 atgatgggtt atgatacaac accggttgaa agagatgaag taactgcagc tacgactgca
    34021 tatggtatta tgaaaggcgt tagagcagta cgcgttcata atgtcgagtt gaatgctaaa
    34081 ttagctaaag gtatagattt tttaaaggag aatgaaaatg caagacacaa tctttcttaa
    34141 aggtatgcgc ttttatggat atcatggtgc tttatcagct gaaaatgaaa tagggcaaat
    34201 tttcaaagtg gatgtaactt tgaaagtaga cttagctgaa gctgggcgta ctgataatgt
    34261 tattgataca gttcattatg gtgaagtgtt cgaagaggtt aaatcaatta tggaaggtaa
    34321 ggccgttaat ttacttgagc atctagctga acgtattgca aatcgtataa attcacaata
    34381 taatcgtgta atggaaacaa aagtgagaat cactaaagaa aacccaccga ttccgggtca
    34441 ttatgatgga gtaggtatcg aaatagtgag ggagaataaa tgattcaagc atacttagga
    34501 ttaggtagta atattggtga tagagaaagc cagttaaacg atgctataaa gattttgaat
    34561 gaatatgatg gtattagcgt atctaatatt tctccgattt atgaaacagc accagttggg
    34621 tatactgagc aacctaactt tttaaatttg tgtgttgaaa ttcaaacaac actcacagta
    34681 ttacaactgt tggaatgttg tttgaagaca gaagaatgtt tacaccgtat tagaaaggaa
    34741 cgatggggtc ctagaacttt agatgtggat attttgttgt atggagaaga aatgatagat
    34801 ttaccaaaac tgtcggtgcc acatccgaga atgaatgaac gtgcatttgt tttaatccca
    34861 ttaaatgata tagcagcaaa tgtcgtagaa ccacgttcga aattgaaagt gaaagattta
    34921 gtttttgtcg atgacagtgt aaagagatat aaataatgta ttgttgagaa cattcatatt
    34981 tattgggaat agatgattga ttattggaga tgtttccgca ttttgattat ctctaaatgc
    35041 atttgattac gaattagtat atgatgattt agtatgtgtt agaattaagt tatttcataa
    35101 aatcaaagta agcaatattt gataaattgc tgtaatttat ttgggctttt gttgaagttt
    35161 gtggaagata atttttatac atttacttag ggttgtatta atgataatcg tattttaaat
    35221 gaataagtaa ttcataaacg aaaacagaaa ttgctttatt acatttacaa gctcttgtaa
    35281 aattaaaaaa gtgataaaat tgatgttatg aatataagaa aacatgccac atcataactt
    35341 taaggtgtaa tggttaatga taaagtatta gaaacatcga aagagatgta tgttgagcaa
    35401 aaatgtctga tattttataa aactttaaag gaaaatgttt gagtgtacca gttggaatac
    35461 taaaggatta caacaagtta aaggagagaa agttatgtca gaagaaatga atgaccaaat
    35521 gttggttcga cgtcaaaaat tacaagaatt atatgatctt ggtatagacc cgtttggttc
    35581 taaatttgac cgttcaggtt tatctagtga tttgaaagaa gagtgggacc agtattctaa
    35641 agaagaattg gtagaaaaag aagcggatag tcatgtcgct atagctggac gattaatgac
    35701 taagcgtggt aaaggtaaag caggatttgc acacgttcag gacttagctg gacaaattca
    35761 aatttacgtt cgtaaagatc aagttggcga tgacgaattt gatttatgga aaaatgctga
    35821 tttaggcgat atcgttggtg ttgaaggtgt aatgttcaaa acaaatactg gcgaattatc
    35881 ggttaaagcg aagaaattca cgctactaac taaatcattg cgaccattac cggataaatt
    35941 ccacggttta caggatattg aacagagata tcgtcaaaga tatttagatt taattacgaa
    36001 cgaagatagc actcgtacat ttattaatcg tagtaaaatc attcaagaaa tgcgtaatta
    36061 tttaaataat aaaggtttct tggaagtaga aacacctatg atgcaccaaa ttgctggtgg
    36121 cgcagctgct agaccatttg taacacatca taatgcatta gatgcaacgt tatacatgcg
    36181 tattgctatt gagttgcatt taaaacgttt aattgtcggt ggacttgaaa aagtatatga
    36241 aattggtaga gtattccgta atgaaggtgt atcaactaga cataaccctg aattcacaat
    36301 gattgaatta tatgaagcat atgcagatta tcatgacatt atggatttaa cagaatctat
    36361 ggtgagacat attgccaatg aagtattagg ttctgcaaaa gtacaataca atggggaaac
    36421 gattgattta gaatctgctt ggactcgttt gcatattgtt gatgctgtaa aagaagctac
    36481 tggtgtggat ttttatgaag ttaaaagtga tgaagaagct aaagctttag ctaaagaaca
    36541 tggtattgaa attaaagata caatgaaata tggtcatatt ttaaatgaat tctttgagca
    36601 aaaagttgaa gaaacactta ttcagccaac gtttatctat ggtcatccga ctgaaatttc
    36661 acctttagcg aagaaaaatc ctgaagatcc tagatttact gatcgtttcg aattgttcat
    36721 tgtaggtaga gagcatgcaa atgcatttac tgaattaaat gatcctattg atcaaaaagg
    36781 tcgttttgaa gcgcaacttg ttgaaaaggc gcaaggtaat gatgaagcgc atgaaatgga
    36841 tgaagattac attgaagcgt tagaatatgg tatgcctccg acaggtggtc ttggtatcgg
    36901 tattgacaga ttggttatgt tattaactga ttctccatca atcagagacg tgttattatt
    36961 cccttatatg agacaaaaat aaatgacgtt gattgttagt aagagctctc gtgtatacaa
    37021 catgtgtatg cgagggtttt cttaattatg gtaattagtt cgtgtttgaa tgtttttgat
    37081 agtaatagtt aacgatagtg gtactatttt tgactgttaa acaaggtagt tggctgatag
    37141 atgaaaatga cgatacgtat atagagtagt tcggatgaga aatgttaacg atagacattg
    37201 agatatctta taacaaaaat tgctatatta gtataattta tcttaatcag ctataaaagt
    37261 actttaaaat tgtatagaat gtgtatggtt ttgtacatat gtgtatgata gaatactaaa
    37321 agtgttatga attagagagc acgagaaatg tcagttttga agaataaaaa agttgattaa
    37381 aagtgttgac tttatcaatt gaatgaagta atatataaaa gtcgtcaaaa acagacgaaa
    37441 cacactaaaa gctgatgtga caaagttcac aacaaagtgt aaaattaact attgcacctt
    37501 attaattaag cgtgtatcat aaataagtaa gttattttgt ctggtggcta tagcaaggag
    37561 gtcacacctg ttcccatgcc gaacacagaa gttaagctcc ttagcgtcga tggtagtcga
    37621 acttacgttc cgctagagta gaacgttgcc aggcaaatga caaatcggag aattagctca
    37681 gctgggagag catctgcctt acaagcagag ggtcggcggt tcgaacccgt cattctccac
    37741 catttattct tagatatagc cggcctagct caattggtag agcaactgac ttgtaatcag
    37801 taggttgggg gttcaagtcc tctggccggc accatctttt gagccattag ctcagctggg
    37861 agagcatctg acttttaatc agagggtcag aggttcgaat cctctatggc tcattacgat
    37921 ttaattttta tatttagcaa aataatgcag aagtagttca gcggtagaat acaaccttgc
    37981 caaggttggg gtcgcgggtt cgaatcccgt cttctgctcc attattttgc cggggtggcg
    38041 gaactggcag acgcacagga cttaaaatcc tgcggtgaga gatcaccgta ccggttcgat
    38101 tccggtcctc ggcaccattt tagcgcccgt agctcaattg gatagagcgt ttgactacgg
    38161 atcaagaggt tatgggttcg actcctatcg ggcgcgccat ttttaaatta attgaataac
    38221 gggaagtagc tcagcttggt agagcacttg gtttgggacc aaggggtcgc aggttcgaat
    38281 cctgtcttcc cgattacttc ttaaatttca ttttatgggg gcttagctca gctgggagag
    38341 cgcctgcttt gcacgcagga ggtcagcggt tcgatcccgc tagtctccac catttatttt
    38401 tacacgatga acattgaaaa ctgaatgaca atatgtcaac gttaattcca aaaaacgtaa
    38461 ctataagtta caaacattat ttagtattta tgagctaatc aaacatcata atttttatgg
    38521 agagtttgat cctggctcag gatgaacgct ggcggcgtgc ctaatacatg caagtcgagc
    38581 gaacgga
//
LOCUS       DAPDIM010000021        38510 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000021 DAPDIM010000000
VERSION     DAPDIM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 38510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38510
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.021"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            165..563
                     /gene="nrdI"
                     /locus_tag="RFE25_001146"
     CDS             165..563
                     /gene="nrdI"
                     /locus_tag="RFE25_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDU2816220.1"
                     /translation="MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVT
                     GTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFE
                     LHGKNKDVIEFKNKVGNFNENHGREKVQSY"
     gene            526..2631
                     /gene="nrdE"
                     /locus_tag="RFE25_001147"
     CDS             526..2631
                     /gene="nrdE"
                     /locus_tag="RFE25_001147"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDU2816221.1"
                     /translation="MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVK
                     DKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFF
                     KDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNA
                     GRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIK
                     GVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRL
                     STISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVE
                     KKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQET
                     SIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAP
                     GVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIA
                     KERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDV
                     EQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTM
                     WYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKS
                     LYYTRNKLLSVEECTSCSI"
     gene            2749..3720
                     /gene="nrdF"
                     /locus_tag="RFE25_001148"
     CDS             2749..3720
                     /gene="nrdF"
                     /locus_tag="RFE25_001148"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDU2816222.1"
                     /translation="MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSE
                     AEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHI
                     FTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFL
                     ETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEK
                     QKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEE
                     REFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK"
     gene            3901..4056
                     /locus_tag="RFE25_001149"
     CDS             3901..4056
                     /locus_tag="RFE25_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816223.1"
                     /translation="MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNAT
                     INEKYYQ"
     gene            4095..5066
                     /locus_tag="RFE25_001150"
     CDS             4095..5066
                     /locus_tag="RFE25_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2816224.1"
                     /translation="MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNI
                     LFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFP
                     TGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLR
                     TNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGL
                     SYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGA
                     IFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ"
     gene            5053..6009
                     /locus_tag="RFE25_001151"
     CDS             5053..6009
                     /locus_tag="RFE25_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDU2816225.1"
                     /translation="MRNNNKKIMLLIAVTLLISMLYLFVGIDFEIFEYQFSSRLRKFI
                     LIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVY
                     LNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPES
                     FLAIQSSMFANFNASNSNLVTFSAVLLVILLVITILLLPYLDVLLLGRAEAINLGISY
                     EKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWI
                     SLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ"
     gene            6006..6767
                     /locus_tag="RFE25_001152"
     CDS             6006..6767
                     /locus_tag="RFE25_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816226.1"
                     /translation="MIQVENLTKTINNQMILEDISIDIEKGKLTSLIGPNGAGKSTLL
                     SAICRLIRFDNGEVKIDGQLMSDYKNNDLSKKISILKQTNHTEMNITVEQLVNFGRFP
                     YSKGRLTKEDHDIVNDALDLLQLQDIRNRNIKSLSGGQRQRAYIAMTIAQDTEYILLD
                     EPLNNLDMKHAVQIMQTLKMLAHKMNKAIVIVLHDINFASCYSDQIVALKNGQLVKSD
                     LKDNVIQSSVLSDLYDMNIQIEHIRNQRICLYFKD"
     gene            6886..7914
                     /locus_tag="RFE25_001153"
     CDS             6886..7914
                     /locus_tag="RFE25_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDU2816227.1"
                     /translation="MKKTVLYLVLAVMFLLAACGNNSDKEQSKSETKGSKDTVKIENN
                     YKMRGEKKDGSDAKKVKETVEVPKNPKNAVVLDYGALDVMKEMGLSDKVKALPKGEGG
                     KSLPNFLESFKDDKYTNVGNLKEVNFDKIAATKPEVIFISGRTANQKNLDEFKKAAPK
                     AKIVYVGADEKNLIGSMKQNTENIGKIYDKEDKAKELNKDLDNKIASMKDKTKNFNKT
                     VMYLLVNEGELSTFGPKGRFGGLVYDTLGFNAVDKKVSNSNHGQNVSNEYVNKENPDV
                     ILAMDRGQAISGKSTAKQALNNPVLKNVKAIKEDKVYNLDPKLWYFAAGSTTTTIKQI
                     EELDKVVK"
     gene            complement(8231..8545)
                     /locus_tag="RFE25_001154"
     CDS             complement(8231..8545)
                     /locus_tag="RFE25_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816228.1"
                     /translation="MPKVYGSLIDTETRCRHYFTEEDIIAIKFKCCNKYYPCYKCHNE
                     FEKHAIKRWSEPSFNEKAILCGVCKHELTINEYMMVERCPNCQSRFNNRCKYHYHIYF
                     EI"
     gene            complement(8563..9486)
                     /locus_tag="RFE25_001155"
     CDS             complement(8563..9486)
                     /locus_tag="RFE25_001155"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDU2816229.1"
                     /translation="MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPT
                     KNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIDVSDDAIIAG
                     SGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQ
                     GSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQP
                     LEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYEN
                     LIHYVQKTVKEKFGIELNREVRIIGEHPKES"
     gene            complement(9613..10131)
                     /locus_tag="RFE25_001156"
     CDS             complement(9613..10131)
                     /locus_tag="RFE25_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDU2816230.1"
                     /translation="MYSNVQPFINSDLTNCFQSQYTEIESLLFNLLDSPVKYTKHIGG
                     THHFKYSTEPILDILVGVENLHDITSLDEKRLNYVGFYRLHHKYTKKVMMAKFNNFHE
                     LKQQVRLHIIQMNTQTFESYLALDYLLSTNDDIALQFNTKKHQILQHSLTIRQYEMQK
                     QQYFEKLCKKYL"
     gene            10251..11129
                     /locus_tag="RFE25_001157"
     CDS             10251..11129
                     /locus_tag="RFE25_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EMYY motif lipoprotein"
                     /protein_id="HDU2816231.1"
                     /translation="MKKIVIIAVLAILFVVISACGNKEKEAQHQFTKQFKDVEQKQKE
                     LQHVMDNIHLKEIDHLSKTDTTDKNSKEFKALQEDVKNHLIPKFEAYYKSAKNLPDDT
                     MKVKKLKKEYMTLANEKKDAIYQLKKFIGLCNQSIKYNEDILDYTKQFEKNRYKVESE
                     IKLADNKSEATNLTTKLEHNNKALRDTAKKNLDDSKENEVKGAIKNHIMPMIEKQITD
                     INQTNISDKHVNNARKNAIEMYYSLQNYYNTRIETIKVSEKLSKVDVDKLPKKGIDIT
                     HGDKAFEKKLEKLEEK"
     gene            11283..11603
                     /gene="ytxJ"
                     /locus_tag="RFE25_001158"
     CDS             11283..11603
                     /gene="ytxJ"
                     /locus_tag="RFE25_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol system redox-active protein YtxJ"
                     /protein_id="HDU2816232.1"
                     /translation="MAIKLSSIDQFEQVIEENKYVFVLKHSETCPISANAYDQFNKFL
                     YERDMDGYYLIVQQERDLSDYIAKKTNVKHESPQAFYFVNGEMVWNRDHGDINVSSLA
                     QAEE"
     gene            12027..13151
                     /locus_tag="RFE25_001159"
     CDS             12027..13151
                     /locus_tag="RFE25_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDU2816233.1"
                     /translation="MKVLVAMDEFHGIISSYQANRYVEEAVASQIETADVVQVPLFNG
                     RHELLDSVFLWQSGQKYRIPVHDADMNEVEGVYGQTDTGMTVIEGNLFLKGKKPIVER
                     TSYGLGEMIKHALDNDAKHVVISLGGIDSFDAGAGMLQALGAQFYDDEGRVVDMRQGA
                     GVIKYIRRMDMSNLHPKMETARIQVMSDFSSRLYGKQSEIMQTYDAHQLHHNQAAEID
                     NLIWYFSELFKSELKIAIGPVERGGAGGGIAAVLNGLYQAEILTSHALVDQLTHLENL
                     VEQADLIIFGEGLNENDQLLETTTLRIAELCHKHQKVAIAICATAEKFDLFESQGVTA
                     MFNTFIDMPETYTDFKMGLQIRHYTVQSLKLLKTHFNVEV"
     gene            complement(13338..14564)
                     /gene="pepT"
                     /locus_tag="RFE25_001160"
     CDS             complement(13338..14564)
                     /gene="pepT"
                     /locus_tag="RFE25_001160"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDU2816234.1"
                     /translation="MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQ
                     QLGLPTDLDENGYLFATLESNIDADVPTVGFLAHVDTSPDFNASNVKPQIIENYDGKP
                     YKLGNTKRVLDPKVFPELNSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPE
                     IKHGTIRIGFTPDEEIGRGPHKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAVITC
                     HGVNVHPGSAKNAMVNAIRLGEQFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATL
                     QYIIRDHDKKQFELRKKRILEIRDDINAHFENYPVKVDISDQYFNMAEKILPLPHIID
                     IPKRVFAKLDIPANTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPYEYASIDVMEK
                     AVQVIIGIVEDIAENH"
     gene            complement(14578..15072)
                     /locus_tag="RFE25_001161"
     CDS             complement(14578..15072)
                     /locus_tag="RFE25_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDU2816235.1"
                     /translation="MLFYLFHFTISFISTVLFSIIFNAPKRLLVACGFVGAIAWTIYQ
                     LTVDLEFGKVGASFLGSLILGLMSHTMSRRYKRPVIIFIVPGIIPLVPGGAAYQATRF
                     LVSNDYTSAVNTFLEVTLISGAIAFGILVSEILYYLYTRIKQLYGKIKGKTYKKSYNM
                     NNRV"
     gene            complement(15090..15851)
                     /locus_tag="RFE25_001162"
     CDS             complement(15090..15851)
                     /locus_tag="RFE25_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDU2816236.1"
                     /translation="MPDSITIIDENKVIDVVLIAGRILLESGAETYRVEDTMNRIAHS
                     YGLHNTYSFVSSTAIIFSLNDRTSTRLIRVQERTTDLEKIALTNSLSRKISNKELTID
                     EAKSEFIHLQHASLQYSFLTNFFAAAIACGFFLFMFGGVASDCWIAVIAGGSAFLTFS
                     FVQRYIQIKFFSEFVAAAVVISIAATFTKLGIATNQDIITIASVMPLVPGILITNAIR
                     DLLAGELLAGMSRGVEAALTAFAIGAGVAIVLLII"
     gene            complement(16047..17117)
                     /locus_tag="RFE25_001163"
     CDS             complement(16047..17117)
                     /locus_tag="RFE25_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDU2816237.1"
                     /translation="MFEAFIYNISVIVAGIYLFHRLQYSENKRMVFSKAYVTVLMTIV
                     SLLLSVYPIPYREDYLIHLTFVPLLFLGRFTNMVYTLSATVIVAIVEIVVFNNSIMYG
                     VTLIVIAAVTSAIGPFLKQNDVLSLLILNVVTIIILFGVALVSPIYTLSEVIILIPIS
                     LIITLASAITFVDIWHFFSLVNRYENEDKYDYLTGLGNVKEFDRHLNEISRKAEKEHQ
                     SIALLLIDIDGFKDVNDTYSHKSGDAVLKQMSQLLKNYVPNQFKIFRNGGEEFSVVIH
                     NYSLDQSVKLAENIRSGVEKSSFHLPNKEVIKLSVSIGVGYLTDDDPKSQRKVFKDAD
                     DMVHVAKNQGRNKVMFNPIINL"
     gene            17435..18490
                     /locus_tag="RFE25_001164"
     CDS             17435..18490
                     /locus_tag="RFE25_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HDU2816238.1"
                     /translation="MVTLLLVAVTMIVSLTITPIVIAISKRLNLVDKPNFRKVHTKPI
                     SVMGGTVILFSFLIGIWIGHPIETEIKPLIIGAIIMYVLGLVDDIYDLKPYIKLAGQI
                     AAALVVAFYGVTIDFISLPMGTTIHFGFLSIPITVIWIVAITNAINLIDGLDGLASGV
                     SAIGLITIGFIAILQANIFITMICCVLLGSLIGFLFYNFHPAKIFLGDSGALMIGFII
                     GFLSLLGFKNITIIALFFPIVILAVPFIDTLFAMIRRVKKGQHIMQADKSHLHHKLLA
                     LGYTHRQTVLLIYSISILFSLSSIILYVSPPLGVVLMFVLIIFSIELIVEFTGLIDNN
                     YRPILNLISRKSSHKED"
     gene            complement(18655..19296)
                     /locus_tag="RFE25_001165"
     CDS             complement(18655..19296)
                     /locus_tag="RFE25_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDU2816239.1"
                     /translation="MTQNIITVKKEHIIENVISKSRFIAHIKPVQNEDEAKAFIAAIK
                     KEHKDATHNCSAYTIGPEMNIQKANDDGEPTGTAGVPMLDILKKLDVHNACVVVTRYF
                     GGIKLGGGGLIRAYSGAVRDVIYDVGRVELREAVPCIVTLNYDQTGKFEYELASTHFM
                     LRNQTYTDKVSYYIDVVKSDYEAFINFLNQMTAGNFDLTEETPKQLPFDIPTE"
     gene            19440..20306
                     /gene="fakB1"
                     /locus_tag="RFE25_001166"
     CDS             19440..20306
                     /gene="fakB1"
                     /locus_tag="RFE25_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid kinase binding subunit FakB1"
                     /protein_id="HDU2816240.1"
                     /translation="MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEI
                     AIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSY
                     QAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYL
                     IVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKV
                     LDIVKDFEEVTLFVINGDHFEDGQALYKKLQEDCPSGYQVAYSEFGPVVAAHLGSGGL
                     GLGYVGRKIRLT"
     gene            20670..21752
                     /locus_tag="RFE25_001167"
     CDS             20670..21752
                     /locus_tag="RFE25_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011382223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDU2816241.1"
                     /translation="MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRM
                     RQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVSPRVDVVVEISKRMKDAFLNEDI
                     DILHQQSSQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKSLQQALKSSSK
                     VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNNKIQKMLYR
                     ILQDQINNQRYTLVFFNNIETMIKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHF
                     DVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPAGKVLFFHEGV
                     SMNMIQAKKEIQRMNKLALKRGWIDE"
     gene            21745..22419
                     /locus_tag="RFE25_001168"
     CDS             21745..22419
                     /locus_tag="RFE25_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDU2816242.1"
                     /translation="MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKA
                     RRCSRCLKHLNQDEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYL
                     CELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPK
                     QSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFK
                     VFAFAR"
     gene            22480..23052
                     /gene="raiA"
                     /locus_tag="RFE25_001169"
     CDS             22480..23052
                     /gene="raiA"
                     /locus_tag="RFE25_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDU2816243.1"
                     /translation="MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKV
                     KTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRD
                     RGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDF
                     FVFTDRETDGTSIVYRRKDGKYGLIQTSEQ"
     gene            23466..25997
                     /gene="secA"
                     /locus_tag="RFE25_001170"
     CDS             23466..25997
                     /gene="secA"
                     /locus_tag="RFE25_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDU2816244.1"
                     /translation="MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKT
                     KQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGD
                     IAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGL
                     NLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSI
                     LIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAE
                     RMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRR
                     FSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYN
                     MTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEY
                     ISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEEL
                     GGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSR
                     LGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSII
                     DEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKG
                     KDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQG
                     IHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFG
                     EAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK"
     gene            26039..26143
                     /locus_tag="RFE25_001171"
     CDS             26039..26143
                     /locus_tag="RFE25_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816245.1"
                     /translation="MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV"
     gene            26312..27422
                     /gene="prfB"
                     /locus_tag="RFE25_001172"
     CDS             join(26312..26383,26385..27422)
                     /gene="prfB"
                     /locus_tag="RFE25_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014667688.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDU2816246.1"
                     /translation="MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPN
                     FWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEV
                     INFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGF
                     KVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFAS
                     CDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQN
                     ERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMV
                     KDHRTNEETGKVDAVMDGDIGPFIEAYLRQTMSHD"
     gene            27576..27683
                     /locus_tag="RFE25_001173"
     CDS             27576..27683
                     /locus_tag="RFE25_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816247.1"
                     /translation="MCLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV"
     gene            27831..28670
                     /locus_tag="RFE25_001174"
     CDS             27831..28670
                     /locus_tag="RFE25_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2816248.1"
                     /translation="MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQ
                     AQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQ
                     TKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPT
                     VPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFK
                     VDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYN
                     YIH"
     gene            28844..29494
                     /locus_tag="RFE25_001175"
     CDS             28844..29494
                     /locus_tag="RFE25_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDU2816249.1"
                     /translation="MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYL
                     ATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVET
                     FIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFE
                     IYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE"
     gene            29491..29727
                     /locus_tag="RFE25_001176"
     CDS             29491..29727
                     /locus_tag="RFE25_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbA family protein"
                     /protein_id="HDU2816250.1"
                     /translation="MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEY
                     FHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR"
     gene            29996..31981
                     /gene="uvrB"
                     /locus_tag="RFE25_001177"
     CDS             29996..31981
                     /gene="uvrB"
                     /locus_tag="RFE25_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002473941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDU2816251.1"
                     /translation="MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATG
                     TGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEA
                     YVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
                     VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEF
                     FGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKEL
                     RDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDD
                     WLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLV
                     YVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERV
                     LVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLR
                     EGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAI
                     DETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKER
                     QKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG"
     gene            31989..34835
                     /gene="uvrA"
                     /locus_tag="RFE25_001178"
     CDS             31989..34835
                     /gene="uvrA"
                     /locus_tag="RFE25_001178"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDU2816252.1"
                     /translation="MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAF
                     DTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVAT
                     VTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR
                     KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETR
                     LADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGAC
                     PTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDK
                     PFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEY
                     TREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSE
                     QDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGV
                     LYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGE
                     HGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKG
                     IDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDK
                     IIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEA
                     CKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFF
                     ENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDE
                     PTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIV
                     ATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK"
     gene            35499..36431
                     /locus_tag="RFE25_001179"
     CDS             35499..36431
                     /locus_tag="RFE25_001179"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDU2816253.1"
                     /translation="MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSH
                     YASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKE
                     LNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSET
                     ALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSI
                     LTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVA
                     AMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE"
     gene            36437..37276
                     /locus_tag="RFE25_001180"
     CDS             36437..37276
                     /locus_tag="RFE25_001180"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDU2816254.1"
                     /translation="MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVK
                     AGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIG
                     GFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLH
                     LPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGR
                     FFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTK
                     KVK"
     gene            37284..37769
                     /locus_tag="RFE25_001181"
     CDS             37284..37769
                     /locus_tag="RFE25_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDU2816255.1"
                     /translation="MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMV
                     LKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEF
                     RYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIR
                     R"
     gene            37777..>38510
                     /locus_tag="RFE25_001182"
     CDS             37777..>38510
                     /locus_tag="RFE25_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDU2816256.1"
                     /translation="MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLEL
                     SPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKA
                     FLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKD
                     AKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTL
                     LLYNTKENEQYQKYLKILNKVVPMND"
BASE COUNT        13826 a         5429 c         7029 g        12226 t
ORIGIN      
        1 ttttctcaaa tataaatcta tgcaattggt ttacatttga gaaaataagt agcttcatta
       61 tagttaatac aatgctgaga taaccatagt aaccatgttg ttaaagcatt ttttaattgg
      121 aatgactact ttatttaaaa gggttgaaga aagaaggtga tccaatgaaa ataatatatt
      181 tttcatttac tggaaatgtc cgtcgtttta ttaagagaac agaacttgaa aatacgcttg
      241 agattacagc agaaaattgt atggaaccag ttcatgaacc gtttattatc gttactggca
      301 ctattggatt tggagaagta ccagaacccg ttcaatcttt tttagaagtt aatcatcaat
      361 acatcagagg tgtggcagct agcggtaatc gaaattgggg actaaatttc gcaaaagcgg
      421 gtcgcacgat atcagaagag tataatgtcc ctttattaat gaagtttgag ttacatggaa
      481 aaaacaaaga cgttattgaa tttaagaaca aggtgggtaa ttttaatgaa aaccatggaa
      541 gagaaaaagt acaatcatat tgaattaaat aatgaggtca ctaaacgaag agaagatgga
      601 ttctttagtt tagaaaaaga ccaagaagct ttagtagctt atttagaaga agtaaaagac
      661 aaaacaatct tcttcgatac tgaaatcgag cgtttacgtt atttagtaga caacgatttt
      721 tatttcaatg tgtttgatat ttatagtgaa gcggatctaa ttgaaatcac tgattatgca
      781 aaatcaatct cgtttaattt tgcaagttat atgtcagcta gtaaattttt caaagattac
      841 gctttgaaaa caaatgataa aagtcaatac ttagaagact ataatcaaca cgttgccatt
      901 gttgctttat acctagcaaa tggtaataaa gcacaagcta aacaatttat ttctgctatg
      961 gttgaacaaa gatatcaacc agcgacacca acatttttaa acgcaggccg tgcgcgtcgt
     1021 ggtgagctag tgtcatgttt cttattagaa gtggatgaca gcttaaattc aattaacttt
     1081 attgattcaa ctgcaaaaca attaagtaaa attgggggcg gcgttgcaat taacttatct
     1141 aaattgcgtg cacgtggtga agcaattaaa ggaattaaag gcgtagcgaa aggcgtttta
     1201 cctattgcta agtcacttga aggtggcttt agctatgcag atcaacttgg tcaacgccct
     1261 ggtgctggtg ctgtgtactt aaatatcttc cattatgatg tagaagaatt tttagatact
     1321 aaaaaagtaa atgcggatga agatttacgt ttatctacaa tatcaactgg tttaattgtt
     1381 ccatctaaat tcttcgattt agctaaagaa ggtaaggact tttatatgtt tgcacctcat
     1441 acagttaaag aagaatatgg tgtgacatta gacgatatcg atttagaaaa atattatgat
     1501 gacatggttg caaacccaaa tgttgagaaa aagaaaaaga atgcgcgtga aatgttgaat
     1561 ttaattgcgc aaacacaatt acaatcaggt tatccatatt taatgtttaa agataatgct
     1621 aacagagtgc atccgaattc aaacattgga caaattaaaa tgagtaactt atgtacggaa
     1681 attttccaac tacaagaaac ttcaattatt aatgactatg gtattgaaga cgaaattaaa
     1741 cgtgatattt cttgtaactt gggctcatta aatattgtta atgtaatgga aagcggaaaa
     1801 ttcagagatt cagttcactc tggtatggac gcattaactg ttgtgagtga tgtagcaaat
     1861 attcaaaatg caccaggagt tagaaaagct aacagtgaat tacattcagt tggtcttggt
     1921 gtgatgaatt tacacggtta cctagcaaaa aataaaattg gttatgagtc agaagaagca
     1981 aaagattttg caaatatctt ctttatgatg atgaatttct actcaatcga acgttcaatg
     2041 gaaatcgcta aagagcgtgg tatcaaatat caagactttg aaaagtctga ttatgctaat
     2101 ggcaaatatt tcgagttcta tacaactcaa gaatttgaac ctcaattcga aaaagtacgt
     2161 gaattattcg atggtatggc tattcctact tctgaggatt ggaagaaact acaacaagat
     2221 gttgaacaat atggtttata tcatgcatat agattagcaa ttgctccaac acaaagtatt
     2281 tcttatgttc aaaatgcaac aagttctgta atgccaatcg ttgaccaaat tgaacgtcgt
     2341 acttatggta atgcggaaac attttaccct atgccattct tatcaccaca aacaatgtgg
     2401 tactacaaat cagcattcaa tactgatcag atgaaattaa tcgatttaat tgcgacaatt
     2461 caaacgcata ttgaccaagg tatctcaacg atcctttatg ttaattctga aatttctaca
     2521 cgtgagttag caagattata tgtatatgcg cactataaag gattaaaatc actttactat
     2581 actagaaata aattattaag tgtagaagaa tgtacaagtt gttctatcta acaattaaat
     2641 gttgaaaatg acaaacagct aatcatctgg tctgaattat cagatgatta gactgctatg
     2701 tctgtatttg tcaattattg agtaacatta caggaggaaa ttatattcat gatagctgtt
     2761 aattggaaca cacaagaaga tatgacgaat atgttttgga gacaaaatat atctcaaatg
     2821 tgggttgaaa cagaatttaa agtatcaaaa gacattgcaa gttggaagac tttatctgaa
     2881 gctgaacaag acacatttaa aaaagcatta gctggtttaa caggcttaga tacacatcaa
     2941 gcagatgatg gcatgccttt agttatgcta catacgactg acttaaggaa aaaagcagtt
     3001 tattcattta tggcgatgat ggagcaaata cacgcgaaaa gctattcaca tattttcaca
     3061 acactattac catctagtga aacaaactac ctattagatg aatgggtttt agaggaaccc
     3121 catttaaaat ataaatctga taaaattgtt gctaattatc acaaactttg gggtaaagaa
     3181 gcttcgatat acgaccaata tatggccaga gttacgagtg tatttttaga aacattctta
     3241 ttcttctcag gtttctatta tccactatat cttgctggtc aagggaaaat gacgacatca
     3301 ggtgaaatca ttcgtaaaat tcttttagat gaatctattc atggtgtatt taccggttta
     3361 gatgcacagc atttacgaaa tgaactatct gaaagtgaga aacaaaaagc agatcaagaa
     3421 atgtataaat tgctaaatga cttgtattta aatgaagagt catacacaaa aatgttatac
     3481 gatgatcttg gaatcactga agatgtgcta aactatgtta aatataatgg aaacaaagca
     3541 ctttcaaact taggctttga accttatttt gaggaacgtg aatttaaccc aatcattgag
     3601 aatgccttag atacaacaac taaaaaccat gacttcttct cagtaaaagg tgatggttat
     3661 gtattagcat taaacgtaga agcattacaa gatgatgact ttgtatttga caacaaataa
     3721 caattaaatt aaaagacctt cacatgtaaa gggaaatagc gattcgtttc gtcttgtctc
     3781 ctacatgttg aaggtctttt ctctatgctt aaaagcgtat gcatattttg aaaaagtaaa
     3841 aattgtattt aatgatgtca atgaggctag aaagtataca agatattgca ttacaaaagg
     3901 gtgttctatt ttactttaag caaacaaaat acacattccg aaaaattaaa tttcagttta
     3961 attgcaaata tcaataaaat tgacactaaa ttatttgaaa ggctattgaa attatggtca
     4021 aaaaacgcta ctattaatga gaaatattat caatgataat gattatcatt aatttaaagg
     4081 gagaaaaatt tgtaatgaag tatttattaa agggaaatat tttgcttcta ttactaatat
     4141 tgttgacaat tatttcgttg ttcataggtg tgagtgaact atcaattaaa gatttactac
     4201 atttaactga atcacagcgg aatattttat tctcaagccg aataccaagg acgatgagta
     4261 ttttaattgc tggaagttcg ttggctttag caggcttgat aatgcaacaa atgatgcaaa
     4321 ataagtttgt tagtccgact acagctggaa cgatggaatg ggctaaacta ggtattttaa
     4381 ttgctttatt gttctttcca accggtcata ttttattaaa actagtattt gctgttattt
     4441 gcagtatttg cggtacgttt ttatttgtta aaatcattga ttttataaaa gtgaaagatg
     4501 tcatttttgt accgctttta ggaattatga tgggtgggat tgttgcaagt ttcacaacct
     4561 tcatctcatt gcgcacgaat gctgttcaaa gcattggtaa ctggcttaac gggaactttg
     4621 ccattatcac aagtggacgc tatgaaattt tatatttaag tattcctctt ttagcattga
     4681 catatctttt tgctaatcat ttcacgattg taggaatggg taaagacttt actaataatt
     4741 taggtttgag ttacgaaaaa ttaattaaca tcgcattgtt tattactgca actattacag
     4801 cattggtagt ggtgactgtt ggaacattac cgttcttagg actagtaata ccaaatatta
     4861 tttcaattta tcgaggtgat catttgaaaa atgctatccc tcatacgatg atgttaggtg
     4921 ccatctttgt attattttct gatatagttg gcagaattgt tgtttatcca tatgaaataa
     4981 atattggttt aacaataggt gtatttggaa caatcatttt ccttatcttg cttatgaaag
     5041 gtaggaaaaa ttatgcgcaa caataataaa aaaataatgc ttttaattgc agtaacgtta
     5101 ttaattagta tgctgtactt atttgtaggt attgattttg aaatatttga atatcaattt
     5161 tcaagtcgtt taagaaagtt catattaatt attttagtag gtgctgccat tgcaacttca
     5221 gtggtgattt ttcaagcgat tacaaataac cgtctattga caccatcaat aatggggtta
     5281 gatgcagttt atttatttat caaagtattg ccagtctttt tatttggaat tcaatcggta
     5341 tgggttacta atgtatattt gaactttata ttaacactta taacgatggt gttattcgca
     5401 ctaatcctat tccaaggtat ctttaaaatt ggacattttt caatttattt tatcttactt
     5461 attggtgtcc ttttaggaac attttttaga agcataacag gttttattca actgattatg
     5521 gatcctgagt catttttagc aatacaaagt agtatgtttg ctaattttaa tgcttctaat
     5581 tcgaatttag ttactttctc agcagtgcta ttagtaatct tattagtcat tacaatttta
     5641 ctattgcctt atttagatgt attgctttta ggtcgtgctg aagcaattaa tcttgggata
     5701 tcgtatgaaa aattaacgcg aattctactt gtaatagtct cagttttagt ttctgtgtca
     5761 actgcattag taggaccaat tacattttta ggtttattaa ctgtaaatct agcgcatgaa
     5821 ctaatgaaga cgtatgaaca taagtatatt ttaattgcga caatttgctt gagttggatt
     5881 agtttattta gtgcgcaatg ggtagttgaa aatgtgtttg aagctacgac agaaatgagt
     5941 atacttattg atttgattgg tggaagttat ttcatttatc tattagttag aaggagaaat
     6001 gcgcaatgat tcaagttgaa aatttaacta aaactataaa taatcaaatg atattggaag
     6061 atattagcat agatatcgaa aaaggtaaat tgacttcttt aattggacct aatggtgcgg
     6121 gtaagagtac tttactttca gcgatatgta ggttaattcg ttttgataac ggtgaagtga
     6181 aaatagatgg acagctcatg tctgattata aaaataatga cttgtcgaaa aaaatatcta
     6241 tattaaaaca aacaaaccat actgaaatga atattacggt agagcagttg gtaaactttg
     6301 gacgattccc ttattctaaa ggtcgtttga cgaaagagga tcatgatatt gtcaatgatg
     6361 cgctagattt gttgcaacta caagatatca gaaatcgtaa tattaagtca ttatctggtg
     6421 gacaacgtca gcgtgcatac attgcaatga caatagcaca agatactgaa tatattttgc
     6481 tagatgaacc attaaataat ttagatatga agcatgctgt tcaaattatg caaacgttaa
     6541 aaatgttagc gcataaaatg aataaagcga ttgtcattgt gttacatgat attaactttg
     6601 cgtcctgtta ttcagatcag attgtagcat tgaaaaacgg acaactagtt aagtcagatt
     6661 tgaaagataa tgtcattcaa agtagtgttt taagtgattt atatgacatg aatattcaaa
     6721 ttgaacatat aagaaatcaa aggatttgtt tatattttaa ggattgataa tttggagaca
     6781 ctttaaaggg gtgatgcgcc aattaaagaa gggttaaacg taaagcattt atttatattt
     6841 cacatcaagc acacagatta agccaaaaga ggagaatatt atattatgaa gaaaacagtc
     6901 ttatatttag tattagcagt aatgttttta ttagcggcat gcggtaacaa ttctgataaa
     6961 gaacaatcaa aatcagaaac taaaggttct aaagatacag taaaaattga aaataactat
     7021 aaaatgcgtg gcgagaaaaa agatggtagt gacgctaaaa aagttaaaga aactgttgaa
     7081 gtaccaaaaa atcctaaaaa tgcagttgtg ttagactatg gcgcattaga tgtaatgaaa
     7141 gaaatgggct tatcagataa agtaaaagca ttacctaaag gggaaggcgg taagtcatta
     7201 ccgaatttct tagaatcatt taaagatgat aaatatacaa acgttggtaa tttaaaagaa
     7261 gtgaattttg ataaaattgc tgcgacgaaa cccgaagtaa tctttatctc tggacgtaca
     7321 gctaatcaaa agaatttaga tgaattcaaa aaagctgcac ctaaagcgaa aattgtttat
     7381 gttggtgcag atgaaaagaa cttaattggt tcaatgaaac aaaacactga aaatatcggt
     7441 aaaatttacg ataaagaaga taaagctaaa gaattaaata aagatttaga taacaaaatt
     7501 gcttcaatga aagataaaac gaaaaacttc aataaaactg ttatgtattt actagttaac
     7561 gaaggtgaat tatcaacatt tggacctaaa ggtcgttttg gtggattagt ttacgataca
     7621 ttaggattca atgcagttga taaaaaagta agtaatagca atcatggaca aaatgtttct
     7681 aacgaatatg ttaataaaga aaatccagat gttattttag cgatggatag aggtcaagcg
     7741 ataagtggta aatcaactgc gaaacaagca ttaaataatc ctgtattaaa aaatgttaaa
     7801 gcaattaaag aagacaaagt atataattta gatcctaaat tatggtactt tgcagctgga
     7861 tcaactacaa ctacaattaa acaaattgag gaacttgata aagttgtaaa ataattttaa
     7921 aagaggggaa caatggttaa aggtcttaat cattgctccc ctcttttctt taaaaaagga
     7981 aatctgggac gtcaatcaat gtcctagact ctaaaatgtt ctgttgtcag tcgttggttg
     8041 aatgaacatg tacttgtaac aagttcattt caataccagt gggctccaaa catagagaaa
     8101 tttgattttc aatttctact gacaatgcaa gttggcgggg cccaaacata gagaatttca
     8161 aaaaggaatt ctacagaagt ggtgctttat catgtctgac ccactcccta taatgttttg
     8221 actatgttgt ttaaatttca aaataaatat gatagtgata tttacagcga ttgttaaacc
     8281 gagattggca atttggacaa cgctctacca tcatatattc attgattgtt aattcgtgtt
     8341 tgcatacacc gcataagatt gctttttcgt taaatgaagg ctcagaccaa cgcttaatgg
     8401 cgtgcttttc aaactcatta tggcacttat agcatggata gtatttatta caacatttaa
     8461 atttaatagc aataatatct tcttcggtaa aataatggcg acagcgtgtt tcagtatcga
     8521 ttaatgaacc ataaacttta ggcatagaca aagctcctta acttacgatt cctttggatg
     8581 ttcaccaata atgcgaactt cacgatttaa ttcaatgcca aatttttctt tgacggtctt
     8641 ttgtacataa tgaataaggt tttcataatc tgtagcagtt ccattgtcta catttaccat
     8701 aaaaccagcg tgtttggttg aaacttcaac gccgccaata cggtgacctt gcaaattaga
     8761 atcttgtatc aatttacctg caaaatgacc aggcggtctt tggaatacac taccacatga
     8821 aggatactct aaaggttgtt tagattctct acgttctgtt aaatcatcca ttttagcttg
     8881 tatttcagtc attttaccag gagctaaagt aaatgcagct tctaatacaa ctaagtgttc
     8941 tttttgaata atgctattac gataatctaa ctctaattct tttgttgtaa gtttaattaa
     9001 cgagccttgt tcgtttacgc aaagcgcata gtctatacaa tctttaactt cgccaccata
     9061 agcgccagca ttcatataca ctgcaccacc aattgaacct ggaataccac atgcaaattc
     9121 aaggccagta agtgcgtaat cacgagcaac acgtgagaca tcaataattg cagcgccgct
     9181 accggctatt atcgcatcat cagatacatc gatatgatct agtgataata aactaattac
     9241 aatgccgcga ataccacctt cacggataat aatatttgag ccatttccta aatatgtaac
     9301 aggaatctca ttttgatagg catatttaac aactgcttgt acttcttcat ttttagtagg
     9361 ggtaatataa aagtcggcat taccacctgt tttagtataa gtgtatcgtt ttaaaggttc
     9421 atcaacttta attttttcat ttgggataag ttgttgtaaa gcttgataga tgtctttatt
     9481 tatcacttct cagtacatcc tttctcatgt ctttaatatc atatagtatt ataccaattt
     9541 taaaattcat ttgcgaaaat tgaaaagaaa gtattagaat tagtataatt ataaaatacg
     9601 gcattattgt cgttataagt attttttaca tagtttttca aagtattgtt gcttttgcat
     9661 ctcatattgt ctaattgtta agctatgttg caatatttgg tgcttttttg tattgaattg
     9721 caaagcaata tcatcattag ttgataagag gtaatcaagt gcaagataag attcaaatgt
     9781 ttgggtattc atttgaatga tatgtagacg cacctgttgt tttagttcat gaaaattgtt
     9841 aaacttcgcc atcataactt tcttagtata tttatgatgc aaacgataaa accctacata
     9901 atttaagcgt ttttcatcta aggatgtaat atcatgcaaa ttttctacac ctactaaaat
     9961 atctaaaatt ggctctgttg aatatttaaa atgatgcgta ccgccaatat gttttgtata
    10021 ttttactggg ctgtctaaga ggttgaataa taatgattca atttcagtgt attgtgattg
    10081 aaaacaatta gttaaatcac tattaatgaa tggttgaaca tttgaataca tgataaactc
    10141 ctttgatatt gaaaattaat ttaatcacga taaagtctgg aatactataa cataattcat
    10201 tttcataata aacatgtttt tgtataatga atctgttaag gagtgcaatc atgaaaaaaa
    10261 ttgttattat cgctgtttta gcgattttat ttgtagtaat aagtgcttgt ggtaataaag
    10321 aaaaagaggc acaacatcaa tttactaagc aatttaaaga tgttgagcaa aaacaaaaag
    10381 aattacaaca tgtcatggat aatatacatt tgaaagaaat tgatcatcta agtaaaactg
    10441 atacaactga taaaaatagt aaagaattta aggcactaca agaagatgtt aaaaaccatc
    10501 tcatacctaa atttgaagca tattataagt cagcaaaaaa tttgcctgat gatacaatga
    10561 aagttaagaa attaaaaaaa gaatatatga cgcttgcaaa tgagaagaag gatgcgatat
    10621 atcaattaaa aaaattcata ggtttatgta atcaatctat caagtataac gaagacattt
    10681 tagattatac gaaacaattt gaaaaaaata gatacaaagt tgaatcagaa attaaattag
    10741 ctgataataa aagtgaagca actaatctta cgacaaaatt agaacataat aataaagcgt
    10801 taagagatac tgcgaagaag aacctagatg atagtaaaga aaatgaagta aaaggcgcga
    10861 ttaaaaatca cattatgcca atgattgaaa aacaaattac cgatattaac caaactaata
    10921 ttagtgataa gcatgttaat aatgcaagga aaaacgcaat agaaatgtat tacagtctgc
    10981 agaactatta taatacacgt attgaaacaa taaaggttag tgagaagtta tcaaaagtcg
    11041 atgtagataa gttgccgaaa aagggtatag atataactca cggcgataaa gcctttgaaa
    11101 aaaagcttga aaaattagaa gaaaaataac tataatcatt tttcaaagtt aaaaattttg
    11161 aatttatggt taacatgtca acttactatg tgtataatgg taaacattga tattaactat
    11221 atgtataaaa atgtcacgca gatgctattt aaatgtgata aatattttta gaggtgaata
    11281 gagtggctat aaagctaagt tcaattgacc aatttgaaca ggttattgag gaaaataaat
    11341 atgtttttgt attaaaacat agtgaaactt gtccaatatc ggcaaatgcg tacgatcaat
    11401 ttaataaatt tttatatgaa cgcgatatgg acggttatta tttgattgtc caacaagaac
    11461 gcgatttgtc agattatatt gctaaaaaaa cgaacgttaa acatgaatca cctcaagcat
    11521 tttattttgt aaatggtgaa atggtttgga atcgagacca cggtgatatc aatgtgtcgt
    11581 cattagcaca agcagaagaa taatgaaact ataggttgga acattttgcc ttacactact
    11641 agacgtgaat agcacaactt aaattcgtgt gaatcagagt agtttggcta taatgatgtt
    11701 ctgacctttt attttatgtc acctttagaa gcagttaagt tagtactttt ttacaaacat
    11761 atgtataatg tattcgagta tttttattga aaatattttg gaaaacgacg aatccaataa
    11821 gaaaatttaa acatgatttg taagttagtt taataggaaa tatatgataa accaaaagaa
    11881 gcatactgtt atttactgga ataattaata atcatgtcat gttaaatgtt cgcatataat
    11941 cacgagataa aatctaaaat ttaagattaa tcttttatga ataaaaaacg tatcacaaca
    12001 aataataaag taaggtggtc aaggttatga aagtattagt agccatggat gagtttcatg
    12061 gaattatttc gagttatcaa gctaatagat atgttgaaga ggcagttgca agccaaattg
    12121 aaactgcaga tgtagttcaa gtaccattgt ttaatggaag acatgaatta ttagattctg
    12181 tatttttatg gcaatctggg caaaagtatc gtataccagt acatgatgca gatatgaatg
    12241 aagttgaagg tgtttacgga caaactgata cagggatgac cgttatcgag gggaatttat
    12301 ttttaaaagg taaaaaacca attgttgaac gaacaagtta tggtttagga gaaatgatta
    12361 aacatgcatt agataatgac gcaaaacatg ttgtaatttc actaggtggg attgatagtt
    12421 ttgatgctgg tgcaggtatg ttacaagcat taggtgctca attctatgat gacgaagggc
    12481 gtgtcgtaga tatgagacaa ggtgctggtg taattaaata tattcgtcgt atggatatgt
    12541 cgaacttaca ccctaaaatg gaaacagcaa gaattcaagt aatgtcggat ttttcaagtc
    12601 gattatatgg taagcaaagt gaaatcatgc aaacttatga tgcgcatcag ttgcatcata
    12661 atcaagcagc agaaatcgat aatttaattt ggtattttag tgagttattt aaaagtgaat
    12721 tgaaaattgc aattggtcca gttgaacgtg gtggtgctgg tggtggaatt gcagcagtct
    12781 tgaatggact gtatcaagct gaaatattaa ccagtcatgc attagtagac caactaacac
    12841 atttagaaaa tttagttgaa caagcggatt taattatttt tggagaagga ttaaatgaaa
    12901 atgatcagtt gctagaaacg acaacattgc gtattgcaga actttgtcat aaacatcaaa
    12961 aggttgccat tgcaatttgt gcaactgctg aaaagtttga tttatttgaa tcacaagggg
    13021 ttacagcaat gtttaataca tttatcgata tgccagaaac ttatactgac tttaaaatgg
    13081 gattacaaat taggcattat acggttcagt ctttaaaact gttgaaaaca cattttaatg
    13141 ttgaggttta gtaaagaagg actaaattga tgatgctgtc atgatggtta ataacattta
    13201 tgatggttag caaaacgaat tagaagatcg aaagtatacg taaaaaatat gaaaaatcac
    13261 gctatcattg cactgaatgt tagcgtgatt tttttattaa ttaagcctga gttgaactag
    13321 tatataatcg tttgttttta gtgattttca gcgatatctt ctacaattcc aatgattact
    13381 tgtactgctt tttccataac atcaatggat gcatattcat atgggccgtg gaagttaccg
    13441 caacctgtaa agatgtttgg agttggtaac cccataaatg acaattgtga accatctgta
    13501 ccaccacgaa taggttcagt gtttgctgga atatctaatt tggcaaagac acgtttaggt
    13561 atatcaataa tatgaggcaa tggtaatatt ttttctgcca tattgaaata ttgatccgat
    13621 atatcaactt taactggata attttcaaaa tgggcattga tatcgtcacg tatttctaaa
    13681 atacgtttct tacgcaattc gaattgtttt ttatcatgat cacgaataat gtattgcaaa
    13741 gttgcttttt caacagttcc ttcaaagttc attaagtgat aaaagccttc gtatccttct
    13801 gttcgctccg gaacttcact atcaggtagc aaactatcga attgttcacc taaacgtatt
    13861 gcgtttacca ttgcattttt agctgaacca ggatgaacat ttacaccgtg gcatgtaata
    13921 accgcttcag cagcgttaaa gctttcatat tgtaattctc catattgact accatccata
    13981 gtataagcaa aatcagcatt gaagcggtca acatcaaatt tatgtggacc acgaccgatt
    14041 tcttcgtctg gtgtaaatcc aatgcgaatg gtaccatgtt taatttctgg atgttcttgt
    14101 aaataacaaa tagcttccat aatttccaca atacccgctt tatcgtctgc acctagtaac
    14161 gatgtaccat cagttaccat taatgtatga ccaactaaac tgttaagttc tggaaatact
    14221 ttaggatcta agacacgttt agtattgcct agtttgtatg gcttaccatc atagttttca
    14281 ataatttgcg gtttaacatt tgaagcattg aaatcaggtg atgtatcaac atgcgccaaa
    14341 aatccaactg ttgggacgtc ggcatcgatg ttactttcta atgtagcaaa taagtagcca
    14401 ttttcatcta aatcagttgg caatcctaat tgttgtaatt ctttttctaa taaatgtaac
    14461 aaatcccatt gcttttcagt tgaaggtgtt gttgtagatt ttggatcaga ttgcgtatca
    14521 attgtcgtat atcttgttaa tctatctatc aattggttct tcattatatt cgacccctta
    14581 aactctatta ttcatgttgt aagatttttt atatgtctta cctttgattt taccatacag
    14641 ttgtttgata cgtgtgtata ggtaatatag aatttcagaa actaatatac cgaaagcaat
    14701 cgcacctgaa atcagtgtaa cttctaaaaa tgtatttaca gcacttgtat aatcattcga
    14761 tactaaaaaa cgagtcgctt gataagctgc accaccaggt actaatggta taatgcctgg
    14821 tactatgaat ataattaccg gtcgtttata tctgcgactc atagtatgac tcattaagcc
    14881 taaaattaag cttcccaaaa atgaagcgcc aacttttcca aactctaaat ctaccgttaa
    14941 ttggtaaatc gtccatgcaa tggcacctac aaatccacat gctactaaga ggcgtttggg
    15001 tgcattgaaa atgatagaga aaagtactgt tgatataaag ctgattgtaa aatgaaataa
    15061 ataaaatagc atgctttaac agtccttcct taaatgatta ataaaacgat tgcgacacca
    15121 gcaccgattg cgaatgctgt taatgcagct tcaacacctc gagacatacc tgcaagtaat
    15181 tcacccgcta ataaatctcg aatggcattg gtaattaata taccagggac aagtggcatg
    15241 acactggcta tagtaatgat atcttgattg gttgcaatgc ctaatttagt aaatgtggct
    15301 gcaatggata tgaccacagc agctgcaaca aactctgaga aaaatttaat ttgtatatag
    15361 cgttgcacaa agctgaatgt taaaaatgcg gatccaccag caatgactgc aatccaacaa
    15421 tctgatgcga caccaccaaa cataaatagg aagaagccac atgcaatggc agctgcaaag
    15481 aaattcgtta aaaaagaata ttgtaatgat gcatgctgta aatgaataaa ttcagattta
    15541 gcttcatcaa ttgtgagttc tttatttgat attttacgtg aaagactatt cgttaaagcg
    15601 attttctcta aatctgttgt acgctcttgt acacgaatta atcttgtact tgttcgatcg
    15661 tttaatgaaa aaataattgc agttgaactg acaaaactat atgtattatg aagaccataa
    15721 ctatgtgcga tacggttcat tgtatcttca actcgatatg tttcagcacc tgattcaagt
    15781 aaaattctac ctgcaattaa tacaacatca atcactttgt tttcatctat aattgtgatt
    15841 gaatctggca tatcaattca cctccaatga tatgtgttat ttatttgaac aattgaagtt
    15901 tacaacttgt tgttacaact ttcaatagtg agactttgtg ttagtatgat gaacttgtat
    15961 ggttcaaatt taaataagaa aaactgttaa tctttgctat tatactatga tttaataata
    16021 gcaaaggatt aacagttttg tcgttgttat aaattgataa tagggttaaa cattactttg
    16081 tttcgccctt gatttttggc tacatgcacc atatcgtctg catctttaaa cactttacgc
    16141 tgtgattttg gatcgtcatc tgttaaataa ccaacaccga tagacactga caatttaata
    16201 acttctttgt ttggtaaatg gaatgatgat ttttcaacac ccgaacgaat attttcagct
    16261 aatttaacac tttgatcaag tgaataattg tgaatgacaa ctgagaactc ttcgccacca
    16321 tttctaaaaa ttttaaattg attcggcaca tagtttttaa gtaattgaga catttgtttt
    16381 aatacagcat cacctgattt gtgtgagtag gtatcattga catctttaaa tccatcgata
    16441 tcgattaata ataaagcgat actttgatgt tctttttcag cttttcgtga aatttcattt
    16501 aaatgtctat caaattcttt tacattacct aagcctgtta agtaatcata tttatcttcg
    16561 ttttcataac gatttacgag tgagaagaaa tgccaaatat cgacaaatgt tatcgctgaa
    16621 gctaaagtga taattaatga aattggtatt aaaatgataa cttccgatag tgtataaata
    16681 ggactcacta acgcgacacc aaataaaatg attattgtaa caacattaag tattaataat
    16741 gatagcacat cattttgttt taaaaatggt ccaatagcac ttgttactgc agcaataaca
    16801 atcaacgtaa caccgtacat aatcgagttg ttaaatacta caatttcaac aattgctaca
    16861 attactgtgg cagataatgt atagaccata tttgtaaatc tacctaaaaa caataaagga
    16921 acgaatgtta agtgaattaa ataatcttca cgataaggga tagggtagac agataataat
    16981 aatgatacga ttgtcattaa aacagtgaca taagccttag aaaaaaccat acgtttgttt
    17041 tctgaatact gtaagcgatg gaataaatag attccagcga ctataacaga tatattgtat
    17101 ataaatgctt cgaacatgtc tgaatcgact cctttaattg accactagct attgtaagtg
    17161 aaaacttaca atttgtcatt agtttacata taaaattaat gtatgatata gactttgatg
    17221 ttaaaatgtt gccttaaatg atatgatgaa aaaatgaata ataggcgata tataagaaat
    17281 gaatcgtata gttgtaaata tgatatcatt gattgagcga attaatttat aataaagcta
    17341 taagatatac gtagaaaata gatatatcat tctataaaga caatattaaa taaatataac
    17401 gttaaaaaca attaatatcg atgaaggtga ataaatggtt acattattac tagttgcagt
    17461 aacaatgatt gtcagtttga cgataacacc aattgttatt gcaatatcga aaagattaaa
    17521 tttagttgat aaaccaaatt ttagaaaagt acacactaaa cctatttcag ttatgggtgg
    17581 tacagtgatt ctcttttcat ttttaatagg tatttggatt ggtcatccta ttgaaacaga
    17641 aatcaaacca cttattattg gtgcgattat tatgtacgta cttgggcttg tagatgatat
    17701 ctacgatttg aaaccgtata taaaattggc tggtcaaatt gccgctgcct tagtagttgc
    17761 tttttatggt gtgactattg attttatttc gttgccaatg ggtacaacga ttcattttgg
    17821 atttcttagt attccaatta ctgtgatttg gattgttgct attacaaatg caattaactt
    17881 aattgatgga ctcgatggtt tggcgtcggg tgtttctgca atcggactca ttacaatagg
    17941 attcattgca attttacaag ctaatatttt cataacgatg atttgttgtg ttttattagg
    18001 ctctttaatt gggtttttat tttacaattt ccatcctgcc aaaatatttt taggtgatag
    18061 tggggcttta atgattggat ttatcatcgg attcctttct ttactcggat tcaaaaatat
    18121 tacaattatt gcattgttct tcccaattgt tatcttagca gttccattca ttgatacttt
    18181 gttcgcaatg attcgacgtg tgaaaaaagg gcagcatata atgcaagctg ataaatcgca
    18241 tttgcatcat aaactattag ctttaggcta cacacataga caaacagtat tattaatcta
    18301 ttcaatctct attttattta gtctttcgag cattattttg tatgtatcgc caccattagg
    18361 tgttgtatta atgtttgtat taatcatatt tagtattgaa ttaattgttg aatttacagg
    18421 attaatagat aacaactacc gaccaatatt aaatttaatt agtcggaaat cgtcacacaa
    18481 agaagattag attttaaaac agtaagtaat aaaataaaaa aatgatgtct gtacttttat
    18541 gttgttataa aggaagacat actcacaaaa aacactagca tggaacgtgc tttccaaatt
    18601 gcaaagtaac aatacgcaat tagagttagc cctcctaagc tagtgttttt atttttattc
    18661 agttggtata tcgaaaggta actgctttgg agtttcttca gtcaaatcga aatttccagc
    18721 agtcatttga tttaaaaagt taataaacgc ttcatagtca cttttaacga catcgatata
    18781 gtagcttacc ttatcagtgt aagtttggtt tcttaacata aaatgagttg aagctaattc
    18841 atattcaaat ttaccagttt gatcataatt cagtgttact atacatggta ctgcttctcg
    18901 tagttcgaca cgcccgacat cataaatgac gtctctaaca gcaccgctat aggcgcgaat
    18961 taaaccgcca ccacctaatt taataccacc aaaatatctt gttactacga cacacgcatt
    19021 atgaacatcg agctttttta atatgtctaa cattgggaca ccggcagttc ctgtcggttc
    19081 accatcatca ttcgcttttt gaatattcat ttcaggtcca atagtatatg cagaacaatt
    19141 atgagtggca tctttatgtt ctttttttat tgcagcaata aatgctttag cttcatcttc
    19201 attttgaaca ggtttgatat gagcaatgaa tcttgattta ctaatcacat tttcaataat
    19261 gtgttctttt ttaacagtaa tgatattttg tgtcataata actccttaat tcataagctt
    19321 aagattattt aatcttcatt atacactgaa aatgacatga ctataaatcg tttgattgcc
    19381 attttctttt taactgaaat attgtatcat tgctatgagt atattttagg aggacgacta
    19441 tgaaaattgc tgtgatgacc gattctacaa gttatctgtc gcaggactta atcgataaat
    19501 ataatattca aatagcgcca ttaagtgtga cttttgatga tggaaagaac tttacagaaa
    19561 gtaatgaaat agcaattgaa gaattttata ataaaatggc atcgtctcaa acgattccga
    19621 caacaagcca accagcaatt ggcgaatgga ttactaaata tgaaatgcta agagatcagg
    19681 gttacacaga tatcattgtc atttgcttat ccagtgggat tagtggaagt tatcaatcta
    19741 gttatcaagc aggggaaatg gttgaaggtg ttaatgtaca tgcatttgat agtaagcttg
    19801 cagcaatgat tgaaggatgt tatgtattac gtgctattga aatggttgaa gaaggatacg
    19861 aaccacagca aattattgat gatttaacta atatgcgtga gcacacaggt gcatatttaa
    19921 ttgttgatga cttaaagaat ttacaaaaaa gtggtcgaat tactggtgct caagcatggg
    19981 ttggaacatt attgaaaatg aagccagttc ttaagtttga agatggcaag attataccag
    20041 aagaaaaagt tcgtactaaa aagcgtgcca ttcaaacatt agaaaagaaa gtattagata
    20101 ttgtaaaaga ctttgaagaa gtaactttat ttgtcataaa tggagatcat tttgaagatg
    20161 gtcaagcgtt atacaaaaag ttacaagaag attgtccttc aggttatcaa gtagcatact
    20221 ctgagtttgg tccagttgtt gcagcacatt taggttctgg tggattaggt ttaggctatg
    20281 ttggcagaaa aataagatta acataattat aaaattttaa taaaagagtc tatattgtaa
    20341 ttggaaatta tctctcgtat acatggcttt aaatgttcat catttgaaag tcaaaatgct
    20401 aaagatataa gaaaatcatt ataatattag gctctttttt acgttgaaat gaggttttaa
    20461 gcattaaaca ttacgggaaa ttaattcatc ctcatacttc acttactaat gaaaaaataa
    20521 aaaaagaagt aacaggtgtc atcaaacaaa attcaaacta ttattgtgtt caatgtgaaa
    20581 gtacaaatcc aaagcatttt tatcagtatg attcctcagt acattccaag aaaattgtat
    20641 attgcagaaa ttgtatatca ctgggtcgaa tggataatgt aacaagatat aaaataacag
    20701 agagttcgca aagttcatca caagcatatt atcatctctc atttgaattg tcggaacagc
    20761 agtcttatgc ctcagaacat attgttcgag ccattagaat gagacaaacg attttgttat
    20821 atgccgtaac aggtgcaggt aagacagaaa tgatgtttca aggcattcaa tatgcaagac
    20881 gacagggaga taatatagct attgtgtcac cgcgtgtaga tgttgttgta gaaattagta
    20941 aacgtatgaa agacgcattt cttaatgaag atatagacat actacaccag caatcaagtc
    21001 aacaatttga agggcatttt gttgtatgca cagtacatca actttaccga ttcaaacagc
    21061 actttgatac tatttttatt gatgaagtcg atgcctttcc tttatcaatg gataaaagtt
    21121 tacaacaagc attgaagtca tcttctaaag ttgaacatgc aacgatttat atgacagcaa
    21181 caccaccgaa acaacttctg tcagagattc cccacgaaaa tataattaaa ttgccagctc
    21241 gctttcataa aaaatcactt ccagttccta aatatcgtta tttcaaactt aataataata
    21301 agattcagaa aatgttatac cgaattttac aagatcaaat taataatcaa cgttatacac
    21361 tggtgttttt taacaatata gaaacaatga ttaaaacatt ttcggtttat aagcagaaaa
    21421 ttactaaatt aacatacgtc catagcgagg atgtttttcg ctttgaaaaa gttgaacaat
    21481 taaggaatgg acatttcgat gtcattttta ctacgacaat attagaacgt ggatttacaa
    21541 tggcaaattt ggatgttgtt gttatcgatg cacatcaata tactcaagag gctttaatac
    21601 aaattgctgg acgtgttgga cgaaaattag aatgtcctgc tggaaaagta ttgttttttc
    21661 atgaaggagt aagtatgaat atgattcaag ctaaaaaaga gattcaaagg atgaacaaat
    21721 tagcattaaa aagaggttgg attgatgaat aattgtttga gttgtggtgc taagttatat
    21781 gaaaatataa ccatttataa tttgttcaag aaacctaata gattatgtga cagatgcaaa
    21841 gagaattggg acaatattaa acttgatatt aaagcaaggc gatgttcaag gtgcttaaaa
    21901 cacttaaatc aagatgaagc gtattgttta gactgcaagt ttctatcggc acactttaat
    21961 ttaatggaac aattatattg tcaatttcaa tatgacggtt taatgaaaga gatgatacat
    22021 cagtataaat ttttgaaaga ctattattta tgtgaattat tggcacattt gattgaaata
    22081 ccacaaacat cttatgacta tattgtgcca attccttctt cgccggcaca tgatttatct
    22141 agaacattta acccggtaga agcagtacta aaagctaaag ggattcgctt tgataagatt
    22201 ttaaagatgt caaatagacc aaaacagtct catttaacta agaaagagcg tctggcagat
    22261 gaaaatccat ttattattga tacggaatta gatttaaatg gcaaggaaat attactcgtt
    22321 gacgatattt atacaactgg attaacaatt catcgtgcag ggtgtaaatt atatgctaaa
    22381 aatatcagaa aattcaaagt gtttgcgttt gcacgatagc gtaaaaatgt taaaatataa
    22441 taaagagtta ccaataaaga ggtttaagga gagattacta tgattagatt tgaaattcat
    22501 ggagataacc tcactatcac agatgctatt cgcaactata ttgaggaaaa aattggtaag
    22561 ttggaacgtt attttaatga cgtaccaaat gcagtggcgc atgttaaagt taaaacttat
    22621 tcaaattcag ctactaaaat tgaagtaaca attccattga aaaatgttac gttaagagct
    22681 gaagagcgaa acgatgattt atacgcaggt attgatttaa ttaataataa acttgaaaga
    22741 caagttcgaa aatataaaac acgtattaat cgtaagagcc gtgatcgagg agatcaagaa
    22801 gtgtttgttg ccgaattaca agaaatgcaa gaaacacaag ttgataatga cgcttacgat
    22861 gataacgaga tagaaattat tcgttcaaaa gaattcagct taaaaccaat ggattcagaa
    22921 gaagcggtat tacaaatgaa tctattaggt catgacttct ttgtattcac agacagagaa
    22981 actgatggaa caagtatcgt ttaccgacgt aaagacggta aatatggctt gattcaaact
    23041 agtgaacaat aaattaagtt taaagcactt gtgtttttgc acaagtgctt ttttatactc
    23101 caaaagcaaa ttatgactat ttcatagttc gataatgtaa tttgttgaat gaaacatagt
    23161 gactatgcta atgttaatgg atgtatatat ttgaatgtta agttaataat agtatgtcag
    23221 tctattgtat agtccgagtc gaaaatcgta aaatatttat aatataattt attaggaagt
    23281 ataattgcgt attgagaata tatttattag tgataaactt gttgacaaca gaatgtgaat
    23341 gaagtatgtc ataaatatat ttatattgat tccacaaatg agtaaataag tataattttc
    23401 taactataaa tgataagata tattgttgta ggccaaacag ttttttagct aaaggagcga
    23461 acgaaatggg atttttatca aaaattcttg atggcaataa taaagaaatt aaacagttag
    23521 gtaaacttgc tgataaagta atcgctttag aagaaaaaac ggcaatttta actgatgaag
    23581 aaattcgtaa taaaacgaaa caattccaaa cagaattagc tgacattgat aatgtcaaaa
    23641 agcaaaatga ttatttagat aaaattttac cagaagcata tgcacttgtt agagaaggct
    23701 ctaaacgtgt attcaatatg acaccatata aagttcaaat tatgggtggt attgcaattc
    23761 ataaaggtga tatcgctgag atgagaacag gtgaaggtaa aacattaaca gcgacaatgc
    23821 caacatactt aaatgcatta gctggtagag gtgttcacgt tattacagtc aatgaatact
    23881 tatcaagtgt tcaaagtgaa gaaatggctg agttatataa cttcttaggt ttgactgtcg
    23941 gattaaactt aaacagtaag acgacagaag aaaaacgtga agcatacgca caagacatta
    24001 cttacagtac taataatgag ctaggttttg attacttacg agataacatg gtgaattatt
    24061 ctgaagatag agtaatgcgt ccattacatt ttgcaatcat tgatgaggtt gactcaattt
    24121 taatcgacga ggcacgtacg ccattaatta tttctggtga agctgaaaag tcaacgtcac
    24181 tttatacaca agcaaatgtt tttgcgaaaa tgttaaaaca ggacgaagat tataaatacg
    24241 atgaaaaaac gaaagccgta catttaacag aacaaggtgc ggataaagct gaacgtatgt
    24301 tcaaagttga aaacttatat gatgtacaaa atgttgatgt tattagtcat atcaacacag
    24361 ctttacgtgc gcacgttaca ttacaacgtg acgtagacta tatggttgtt gatggcgaag
    24421 tactaattgt cgatcaattt acaggacgta caatgccagg ccgtcgtttc tcagaaggtt
    24481 tacaccaagc tattgaagcg aaggaaggcg ttcaaattca aaatgaatct aaaactatgg
    24541 cgtctattac attccaaaac tatttcagaa tgtacaataa acttgcgggt atgacaggta
    24601 cagctaaaac tgaagaagaa gaatttagaa atatttataa catgacagta actcaaattc
    24661 cgacaaataa acctgtgcaa cgtaacgata agtctgattt aatttacatt agccaaaaag
    24721 gtaaatttga tgcagtagta gaagatgttg ttgaaaaaca caaggcaggg caaccagtgc
    24781 tattaggtac tgttgcagtt gagacttctg aatatatttc aaatttactt aaaaaacgtg
    24841 gtatccgtca tgatgtgtta aatgcgaaaa atcatgaacg tgaagctgaa attgttgcag
    24901 gcgctggaca aaaaggtgcc gttactattg ccactaacat ggctggtcgt ggtacagata
    24961 tcaaattagg tgaaggcgta gaggaattag gcggtttagc agtaataggt acagaacgac
    25021 atgaatctcg tcgtattgat gaccagttac gtggtcgttc tggacgtcaa ggtgataaag
    25081 gggatagtcg cttctattta tcattacaag atgaattaat gattcgtttt ggttctgaac
    25141 gtttacagaa aatgatgagc cgactaggtt tagatgactc tacaccaatt gaatcaaaaa
    25201 tggtatcaag agctgtagaa tcagcacaaa aacgtgtaga aggtaataac ttcgacgcgc
    25261 gtaaacgtat cttagaatac gatgaagtat tacgtaaaca acgtgaaatt atctataacg
    25321 aaagaaatag tattattgat gaagaagaca gctctcaagt tgtagatgca atgctacgtt
    25381 caacgttaca acgtagtatc aattactata ttaatacagc agatgacgag cctgaatatc
    25441 aaccattcat cgactacatt aatgacattt tcttacaaga aggtgacatt acagaggatg
    25501 atatcaaagg taaagatgct gaagatattt tcgaagtcgt ttgggctaag attgaagcag
    25561 catatcaaag tcaaaaagat atcttagaag aacaaatgaa tgagtttgag cgtatgattt
    25621 tacttcgttc tattgatagc cattggactg atcatatcga cacaatggat caattacgtc
    25681 aaggtattca cttacgttct tatgcacagc aaaatccatt acgtgactat caaaatgaag
    25741 gtcatgaatt atttgatatc atgatgcaaa atatcgaaga agatacttgt aaattcattt
    25801 taaaatctgt agtacaagtt gaagataata ttgaacgtga aaaaacaaca gagtttggtg
    25861 aagcgaagca cgtttcagct gaagatggta aagaaaaagt gaaaccgaaa ccaatcgtta
    25921 aaggcgatca agttggtcgt aacgatgatt gtccatgtgg tagtggtaaa aaattcaaaa
    25981 attgccatgg aaaataaatg atataaaata actccttcca attaaacacc tatagtttgt
    26041 gttatgggag gagtcttttt attttacaag cgttaaatac tttaaaaaat gtgaagaagt
    26101 tgttaaacgt tgttatgtac ttagttttaa aaaatcggtt taggcatatg tcgatgataa
    26161 atgtactgat ttttaacaat aaaagcataa actaattgtc agtgtgctta tatttcttaa
    26221 cattgttatt taacaaaatt atgttaaaat ttagcattat aaaagataca aatcaatgac
    26281 ttgaattgaa atttaaatag gagcgaaggc tatggaatta tcagaaatca aacgaaatat
    26341 agataagtat aatcaagatt taacacaaat tagggggtct ctttgactta gagaacaaag
    26401 aaactaatat ccaagaatat gaagaaatga tggcagaacc taatttttgg gataaccaaa
    26461 cgaaagcgca agatattata gataaaaata atgcgttaaa agcaatagtt aatggttata
    26521 aaacactaca agcagaagta gatgacatgg atgctacttg ggatttatta caagaagaat
    26581 ttgatgaaga aatgaaagaa gacttagagc aagaggtcat taattttaag gctaaagtgg
    26641 atgaatacga attgcaatta ttattagatg ggcctcacga tgccaataac gcaattctag
    26701 agttacatcc tggtgcaggt ggcacggagt ctcaagattg ggctaatatg ctatttagaa
    26761 tgtatcaacg ttattgtgag aagaaaggct ttaaagttga aactgttgat tatctacctg
    26821 gggatgaagc ggggattaaa agtgtaacat tgctcatcaa agggcataat gcttatggtt
    26881 atttaaaagc tgaaaaaggt gtacaccgac tagtacgaat ttctccattt gattcatcag
    26941 gacgtcgtca tacatcattt gcatcatgcg acgttattcc agattttaat aatgatgaaa
    27001 tagagattga aatcaatccg gatgatatta cagttgatac attcagagct tctggtgcag
    27061 gtggtcagca tattaacaaa actgaatcgg caatacgaat tacccaccac ccctcaggta
    27121 tagttgttaa taaccaaaat gaacgttctc aaattaaaaa ccgtgaagca gctatgaaaa
    27181 tgttaaagtc taaattatat caattaaaat tggaagagca ggcacgtgaa atggctgaaa
    27241 ttcgtggcga acaaaaagaa atcggctggg gaagccaaat tagatcatat gttttccatc
    27301 catactcaat ggtgaaagat catcgtacga acgaagaaac aggtaaggtt gatgcagtga
    27361 tggatggaga cattggacca tttatcgaag catatttaag acagacaatg tcgcacgatt
    27421 aatatatatt ttaaaaccga ggctctaaaa gggcgtcggt ttttggtttt tttaaaggta
    27481 gctaaataaa ttgtaaatta gattttggaa tatgatttgt ttatgaatat ttaagtacaa
    27541 ttcggtagat agagttagaa tatatttttt aaaagttgtg tttgttaaaa caacatatgc
    27601 agtgtgcatt tagtaatatt acctatggcg attttcaagg tattgaatta atcgttgaaa
    27661 acgttctcaa ttacatggta tgaatacatt ttacactatg ataaaaggtt gtattctttt
    27721 tatattgtta accatttgat tacatcgtta taacaatagc ttttgacaaa atgtattgtg
    27781 ctatagtatt tgcatactta aaatactaac agcaaaggaa tgacagcaag atgaaaaaaa
    27841 ctcttacagt gacggtttcg tcagtgttag cttttttagc tttaaataat gcagcacatg
    27901 cacaacaaca tggcacacaa gtaaaaacac ctgttcaaca taactatgta tcaaatgttc
    27961 aagcacaaac gcaatcaccg acaacttata cagtagttgc tggcgattca ttatataaga
    28021 ttgctttaga gcatcactta acgttgaatc aattatattc atacaatcct ggtgtaacac
    28081 ctttaatttt tcctggtgac gtgatttcac ttgtgcctca aaataaagtg aaacaaacta
    28141 aagcggttaa atcaccagta agaaaagcaa gccaagctaa aaaggtagta aaacaacctg
    28201 tacaacaagc gtctaaaaaa gtagtagtta agcaagcacc taagcaagca gtagctaaga
    28261 cagttaatgt agcatataaa cctgctcaag tacaaaaatc agtaccaact gtacctgttg
    28321 cacataacta caataaatca gttgctaaca gaggaaactt atatgcttat ggaaactgca
    28381 catattatgc cttcgatcgt cgtgcacaat taggtagaag tataggaagt ttatggggca
    28441 atgcaaataa ctggaattac gcagcaaaag ttgcaggatt taaagtagat aaaacaccag
    28501 aagttggcgc tattttccaa acagctgctg gcccatatgg acatgttggt gttgttgaat
    28561 ctgtaaaccc taatggaaca attactgttt cggaaatgaa ctatgctgga tttaatgtta
    28621 aatcttcaag aacaatttta aatccaggaa aatataatta catccactaa gtaatatatc
    28681 aagacaagac tatcctctta gcctgtttaa gtaacaggtt gagaggattt tttggtatca
    28741 tttaatcaga gttatataaa gaagatattt aaatgatatt taattgattg atatgtaaaa
    28801 agaaagtata atttatgatt aattaatgga ggaggtaatt gaaatgggtg tacatcaata
    28861 ttttaaaaga ttatcagata tggaaagact tataagatta cctggaaaat ttaaatattt
    28921 tgaacacaat gttgcagcac actcctttaa agtaactaaa attgctcaat atctagcaac
    28981 agttgaagaa tatcatggtc gaaagattaa ttggaaaagc ttatatgaaa aagcattaaa
    29041 tcatgatttc gctgaagtgt ttactggtga tataaaaaca cctgttaaat atgcgagtag
    29101 tgaattaaaa aaattatttt cgcaagttga agaagaaatg gtagagacct ttattgaaga
    29161 agaaattcca ttacaatata gagatgttta taagcaacga ctgcaagaag gtaaagatga
    29221 ttcattagaa ggccaaatac tttcagttgc tgataaaatt gatttgcttt atgaaacatt
    29281 tggagaaata caaaaacgta atcccgaaga attatttttc gaaatttatg aaatgagtct
    29341 agaaacaatt attcaatttg accatttagc atctgtacaa gattttatta ataatatcat
    29401 tccagaaatg ttgactgaaa actttatacc tagaacagaa ttaagagaaa caaccatgaa
    29461 cattttaaat aaaagaaaag aggaaaatga atgatatggt attttagcgc agcattcttt
    29521 ccatgtgtct tggtagtatt atttagtgta ataacaagaa gtaaatgggt cggtactatt
    29581 ctgacattaa ttttaattgg tgcctcaatc tataaagagt atttccataa cgagtggatt
    29641 atttttattg atgtagtgtc attattagct ggttatttaa ttatagatca actcgaattt
    29701 cataaacatc aagatgaaga tcgctaagat taactttaaa ataatgtttc aaacaaattt
    29761 gttgaaacaa aacgatgatt aatataatgt gtatttacat actaaaaata acaagataaa
    29821 cgatttgatt taaggcaagc atagttagca caactatgtt tgtttttctt tgttcgacat
    29881 ttttacgaac aaacgtttgc tttttgtgtg gctactttgc taaaatatgt aatgagaaag
    29941 cgaagagttg agcggaaata taaataatac gttgaaagag gaggcatatg tgacaatggt
    30001 tgaacattat ccttttaaaa tacattctga ttttgagcct caaggtgacc aaccgcaagc
    30061 aattaaggaa atcgtggatg gtattaaagc ggggaaaaga catcaaactt tattaggtgc
    30121 aactggcaca gggaaaacat ttacgatgag taatgttatt aaagaagttg ggaaaccaac
    30181 gttaattatc gcacataaca aaacattagc agggcaatta tatagtgagt ttaaagaatt
    30241 ttttcctgaa aacagggtgg aatactttgt aagttactat gattattatc aacctgaggc
    30301 atacgtaccg tctactgaca cttttattga aaaagatgcc tcaatcaatg atgaaattga
    30361 tcaactacga cattctgcta caagtgcatt atttgaacgc gatgatgtaa ttattattgc
    30421 tagtgtaagt tgtatatatg gtttaggtaa tcctgaagaa tataaagatt tagtagtaag
    30481 tgttcgagtt ggtatggaaa tggatagaag tgaattactt agaaaacttg tagatgtgca
    30541 atatacacga aatgacatcg atttccaacg aggaacgttt cgagtgcgtg gtgatgtagt
    30601 tgaaatattc ccagcctcta aagaagaact ttgtataagg gttgagtttt tcggcgatga
    30661 gattgaccgt atccgagaag ttaactacct aacaggtgaa gtgttgaaag aaagagaaca
    30721 ttttgcgata ttcccagctt ctcacttcgt aacacgtgaa gaaaagttga aagttgcgat
    30781 tgaacgtatt gaaaaagaat tggaagaacg attgaaagaa ttacgagatg agaataaatt
    30841 actagaagcg caaaggttag aacagcgtac caactatgat ttagaaatga tgcgagagat
    30901 gggattctgt tcaggaattg aaaactattc cgtacattta actttgcgac cactgggttc
    30961 gacaccgtat actttattgg attactttgg cgatgattgg ttagtaatga ttgatgaatc
    31021 acatgtgaca ttaccacaag ttcgaggcat gtataacgga gacagagcgc gtaaacaagt
    31081 tttggtggat catggattta gattaccgag tgcattagat aaccgtccac ttaaatttga
    31141 agaatttgaa gaaaagacaa aacaacttgt gtatgtatct gcaacgcctg gaccatacga
    31201 aattgaacat acggataaga tggttgaaca aattattcgt cctactggtt tactggatcc
    31261 taaaattgag gttagaccta ctgaaaatca aattgacgat ttattaagtg aaattcaaac
    31321 aagggttgag cgtaatgaac gcgtacttgt tacaacgctc actaaaaaga tgagtgaaga
    31381 tttaaccaca tacatgaaag aagcgggtat taaagttaat tatctgcatt cagaaatcaa
    31441 gacattagaa cgaatcgaaa taattagaga cttacgaatg ggtacatatg atgttatcgt
    31501 aggtattaat ttattaagag agggtattga tataccagaa gtttctctag ttgtcatatt
    31561 agatgcagat aaagaaggat ttttacgttc taaccgctca ttaattcaaa caataggtag
    31621 agctgcgcgt aacgataaag gtgaagtcat tatgtatgcc gataaaatga ctgattcgat
    31681 gaagtatgca attgatgaga cacaacgtcg tcgagaaata cagatgaaac ataatgaaaa
    31741 acatggtatt acacctaaaa caattaataa aaaaatacat gatttaatta gtgctactgt
    31801 tgaaaatgac gaaaataatg acaaagcaca aactgtgata cctaagaaga tgacgaaaaa
    31861 agaacgtcaa aagacaatcg acaatataga aaaagaaatg aaacaagcag cgaaagattt
    31921 agatttcgag aaagctacag aattaagaga tatgttattt gaattaaaag cagaagggtg
    31981 acaagtaaat gaaagaacca tccatagtag taaaaggtgc tcgtgcgcat aacttgaaag
    32041 atattgatat cgaactacct aaaaataaat taattgttat gacaggttta tctgggtcag
    32101 gtaaatcgtc attagcattc gatactatat atgctgaagg acaacgacgt tatgttgaat
    32161 cattaagtgc ctatgcgcgt caatttttag gccaaatgga caaaccagat gttgatacaa
    32221 ttgaaggatt atcgccagca atttcaatag atcaaaaaac aacaagtaaa aatccaagat
    32281 caactgtagc aacagtaaca gaaatatatg attatatacg tttgttatat gcacgtgttg
    32341 gtaaacctta ctgtccaaat cacaatatag aaattgaatc gcaaacagta caacaaatgg
    32401 ttgaccgcat tatggaatta gaggcacgta caaagattca attattagca cctgtcatcg
    32461 ctcatcgtaa aggtagtcat gaaaagctaa tcgaagatat tggtaaaaaa ggttatgtac
    32521 gtttaagaat cgatggcgaa attgttgatg taaatgatgt acctacttta gataagaaca
    32581 agaatcatac aatagaagtt gttgtagacc gattagttgt taaagatgga attgaaacac
    32641 gactagctga ctctatagaa actgcgttag agctttcaga aggacaatta acagttgatg
    32701 tcattgacgg ggaagacctt aagttttcag aaagccatgc ttgtcctata tgtggatttt
    32761 caatcggaga gttagaacca agaatgttta gctttaacag tccttttggt gcttgtccga
    32821 catgtgatgg cttaggccaa aagttaacag tcgatgtaga cttggttgtt cccgacaaag
    32881 ataagacgct aaacgaaggt gcaatagaac cttggatacc gacgagttct gatttttatc
    32941 caacattgtt aaaacgtgtt tgtgaagttt ataaaatcaa tatggataaa ccttttaaaa
    33001 agttaacaga acgtcaacgt gatattttat tgtatggttc tggtgacaaa gaaattgaat
    33061 ttacatttac acaacgtcaa ggtggtacta gaaaacgaac aatggttttc gagggtgtag
    33121 ttcctaatat aagtagacga ttccatgaat ctccttcaga atatacacgt gaaatgatga
    33181 gtaaatatat gaccgaacta ccttgtgaaa cttgtcatgg aaagcgattg agtcgtgaag
    33241 cgttatctgt ttatgtaggt ggtttaaata ttggtgaagt agtcgaatat tcaatcagtc
    33301 aagcgctgaa ctattataaa aacattgatt tgtcagaaca agatcaagcg attgcaaatc
    33361 aaatattgaa agaaattatt tcccgactca cttttttaaa taatgtggga cttgaatatt
    33421 taacgctaaa cagagcttca ggtacacttt caggtggtga agcacaacgt attcgattgg
    33481 caacgcaaat tgggtcgcgt ttgactggtg tcttatatgt attagatgag ccatcaattg
    33541 gactgcatca aagagataat gatcgattaa ttaatacact taaagaaatg agagatttag
    33601 gaaatacttt aattgtagtt gaacacgatg atgatacaat gcgtgcggct gattacttag
    33661 tggatatagg gcctggtgct ggtgaacatg gaggacaaat tgtgtctagt gggacacctc
    33721 aaaaggtaat gaaagataaa aaatcattaa caggacaata cttgagtggt aagaaacgta
    33781 ttgacgtacc tgaatatcgc agaccggctt cagatcgtaa aatttctata cgtggagcta
    33841 gaagcaacaa tcttaaaggg attgatgtgg acataccact atcaatcatg acggttgtta
    33901 caggtgtatc aggttctggt aaaagctcat tagtaaatga agtattatac aaatcattag
    33961 ctcaaaaaat taataaatct aaagtaaagc caggattgta cgataagatt gaaggtattg
    34021 atcaacttga taaaattatt gatattgatc aatcaccgat aggtagaacg ccacgctcta
    34081 atccagcaac atatactggt gtgtttgatg atatacgtga tgtgtttgcg caaacaaatg
    34141 aagctaaaat tcgaggatat caaaaagggc gttttagttt taatgtaaaa ggtggacgct
    34201 gtgaagcttg taaaggtgac ggtattatta aaattgaaat gcatttttta cctgatgttt
    34261 atgttccttg tgaagtgtgt gatggtaaac gatataatcg tgagacacta gaggttactt
    34321 acaaaggtaa aaatattgct gacattttag aaatgactgt tgaagaagca acacaatttt
    34381 ttgaaaatat tcctaagatt aagcgcaagt tacaaacact agttgatgtt ggtcttggat
    34441 acgtcacatt aggtcaacaa gctacaacgt tatcaggtgg tgaggctcaa cgtgtgaaac
    34501 ttgcatctga acttcataaa cgttcaactg gtaaatctat ttatatccta gacgaaccaa
    34561 caacagggtt acatgttgac gatattagca gattattaaa agtattaaat cgattagttg
    34621 aaaatggtga cactgttgta attattgaac ataacctaga tgttatcaaa acagcagact
    34681 atattatcga cttaggtcct gaaggtggta gtggcggtgg tactattgtt gcgactggca
    34741 cacccgaaga tattgctcag acaaagtcat catatacagg aaagtattta aaagaagtac
    34801 ttgaacgaga taaacaaaat actgaagata aataagatta aaagaagtga agggtgttgt
    34861 aaatttaccc ttcacttctt tttattaatt tagtaatgaa tagtagaaag aaaagatgcg
    34921 taaaaagaat tatgttaaga tagggtcaat ctagagttgc taaacataaa tcgaaactga
    34981 gagtgggaca gaaatgataa agaatcacta atgatttatt atgtagtggt tctttgtcat
    35041 tagccacagc tattgtgtac ttaaaaatag gaatgcatga gtgcaactca tgcataagaa
    35101 atactaattt ctaaagaaaa agtatttctt tatgttgggg cccaccccaa cttgcattgt
    35161 ttgtagaatt tcttttcgaa attctctgtg ttggggcccc gccaacttgc attgcctgta
    35221 gaatttcttt tcgaaattct ttatgttggg gccccgccaa ctaattacaa tatatcattg
    35281 tagagcttag gtcattgatt tatggctcgg acttttatgg cgatatgaac catgtaaatt
    35341 aagcaagcaa taaattaatg attgatattg acttgtaaaa taataacaat aatgaacaat
    35401 taatatttat tttagctttt caatgtagat tggtgttata tttttgatat gataagaaga
    35461 gatgtaagag tagggataaa tacaattgag gtgaacccat gttaacgaca gaaaaactag
    35521 ttgaaacatt aaagttagat ttaatcgctg gtgaagaagg actatcgaag ccaattaaaa
    35581 atgctgatat atcaagacca ggcttagaga tggcaggtta tttttcacat tatgcgtcag
    35641 atagaataca actattagga acaacggaac tatcgtttta caatttatta ccagataagg
    35701 atcgcgcagg tcgtatgcgt aaactatgca gaccagaaac gcctgcaatt attgtgacac
    35761 gtggattgca gccaccagaa gaattagttg aagctgcaaa agaattaaat accccactta
    35821 tagttgctaa agatgcgact acaagtttaa tgagtcgctt aacaacgttt ttagagcatg
    35881 cacttgcaaa gacgacatct ttacatggtg ttttagtaga tgtttacggt gttggtgtac
    35941 taattaccgg tgattcagga ataggtaaaa gtgagactgc gttggaatta gttaaacgtg
    36001 ggcatagatt agtagcagat gataatgtag aaatacgtca aattaataaa gatgaactaa
    36061 tagggaaacc accaaagtta atagaacatc tattagaaat acgtggacta ggtattatca
    36121 atgttatgac tttatttggc gcgggttcaa tattaactga aaaacgaatt agattaaata
    36181 ttaatttgga aaactggaac aagcaaaagt tatatgaccg cgtaggtctt aatgaagaga
    36241 cgctaagtat tttagatact gaaatcacta aaaaaacaat acctgtaaga cctggtagaa
    36301 atgttgcggt aattattgag gtcgctgcaa tgaactatcg attaaatatc atgggcatta
    36361 acactgccga agaatttagt gaaagattaa atgaagaaat tatcaagaac agtcataaga
    36421 gtgaggagta ggttgaatgg gtattgtatt taactatata gatcctgtgg catttaactt
    36481 aggaccactg agtgtacgat ggtatggaat tatcattgct gtcggaatat tacttggtta
    36541 ctttgttgca caacgtgcac tagttaaagc aggattacat aaagatactt tagtagatat
    36601 tattttttat agtgcactat ttggatttat cgcggcacga atctattttg tgattttcca
    36661 atggccatat tacgcggaaa atccaagtga aattattaaa atatggcatg gtggaatagc
    36721 aatacatggt ggtttaatag gtggctttat tgctggtgtt attgtatgta aagtgaaaaa
    36781 tttaaaccca tttcaaattg gtgatatcgt tgcgccaagt ataattttag cgcaaggaat
    36841 tggacgctgg ggtaacttta tgaatcacga ggcacatggt ggaccggtgt cacgcgcttt
    36901 tttagaacaa ttacatttgc ctaattttat aatagaaaat atgtatatta acggccaata
    36961 ttatcatcca acattcttat atgaatccat ttgggatgtc gctggattta ttatcttagt
    37021 taatattcgt aaacatttaa aattaggaga aacattcttt ttatatttaa cttggtattc
    37081 aattggtcga ttctttatag aaggattacg tacagatagc ttaatgctca caagtaatat
    37141 tagagttgca caattagtat caattctttt aattttaata agtataagtt taattgtata
    37201 tagaaggatt aagtataatc caccgttgta tagcaaagtt ggggcgcttc catggccaac
    37261 aaaaaaagtg aagtagtgat attttgagaa aatttttatc aaaaacacat catcatacaa
    37321 accctttatg gcgtgtatac cgtcttgtta aattttcgaa agtttttaag aatgtaatta
    37381 tcattgaatt ttcgaaattt attccaagta tggtactgaa aagacatata tataaacaac
    37441 ttttaaatat taatatcggt aatcaatcat cgatagctta taaagtaatg ttagatattt
    37501 tttacccaga actgattacg attggtagta acagtgttat tggttacaat gtaacaattt
    37561 tgacgcatga agcattagtt gatgaatttc gttatggacc agtgacgata ggatctaaca
    37621 ctttgattgg tgcaaatgct accattttac ccggtataac gattggtgac aatgtaaaag
    37681 ttgcagctgg tacggttgtt tcaaaagata taccggataa tggatttgca tatggcaacc
    37741 ctatgtatat aaaaatgatt aggaggtgac aattttatgg cgcaaaagaa taataatgta
    37801 attccaatga cttttgatga tgcattttat cgtaaaatgg ctaaacagaa gtttaaacaa
    37861 agagaatata aacgagctgc tgaatacttt gaaaaagtgt tagaattgtc acctgatgat
    37921 ctggaaattc aaattgatta tgcacaatgt ctagtgcaac ttggtattgc taaaaaagca
    37981 gaacatttat tttatgacaa tattatttat aataggcatc tagaagatag cttttatgaa
    38041 ttgagtcagc tcaacattga agttaacgaa ccaaacaagg cattcttgtt tggtattaat
    38101 tatgttattg ttagcgacga ccaagattat agagatgaat tagatcaaat gtttgatgtg
    38161 aaatatcaaa gcgaagaaca aattgaactt gaagctcaat tgtttgtagt tcaaatacta
    38221 ttccaatatc ttttttctca aggtcgatta aaagatgcaa agaattatgt cttacatcaa
    38281 ccacaagaag ttcaagatca tcgtgtcgta cgtaatttat tggcaatgtg ttatttatat
    38341 ctcggtgaat atgatacggc taaagcattg tacgaagcac tattacaaga ggatagtaca
    38401 gatatatatg cattatgcca ttatactttg ctactttata acactaagga aaatgaacaa
    38461 tatcaaaaat atttaaaaat attaaacaaa gttgtaccta tgaatgacga
//
LOCUS       DAPDIM010000022        38153 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000022 DAPDIM010000000
VERSION     DAPDIM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 38153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38153
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.022"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            86..1654
                     /locus_tag="RFE25_001183"
     CDS             86..1654
                     /locus_tag="RFE25_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDU2816257.1"
                     /translation="MIEKLVTFLNEVVWSKPLVYGLLITGVLFTLRMRFFQVRHFKEM
                     IRLMFQGEKSPNGISSFQAIAMSLAGRVGTGNIVGVSTAIFIGGPGAVFWMWITAFLG
                     ASSAFIESTLGQIFKRVENNEYRGGPAYYIEYGIGGKFGKIYGIIFAIVTIISVGLLL
                     PGVQSNAIASSMHNAIHVPQWLMGAIVVVILGLIIFGGVRSIANVATAVVPFMAIIYI
                     LMAVIIICINIQEVPALFALIFKSAFGLQSAFGGIVGAMIEIGVKRGLYSNEAGQGTG
                     PHAAAAAEVSHPSKQGLVQAFSVYIDTLFVCTATALIILISGTYNVTDGTVNANGTPH
                     LIKDGGIYVENATGKDYSGTAMYAQAGIDKAFHGSGYQFDPTFSGVGSYFIAFALFFF
                     AFTTILSYYYITETNVAYLTRNQNNQVSSIFINIARVIILFATFYGAVKTADVAWAFG
                     DLGVGLMAWLNIIAIWILHKPAVNALKDYEIQKKRLGNGYNAVYQPDPNKLPNAVFWL
                     KTYPERLKQARAKK"
     gene            1799..2557
                     /locus_tag="RFE25_001184"
     CDS             1799..2557
                     /locus_tag="RFE25_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDU2816258.1"
                     /translation="MSEFKTGKINKHVLYSNILNRDVTISIYLPESYNQLVKYNVILC
                     FDGLDFLRFGRIQRTYESLIKEARIDDAIIVGFHYEDVDKRREEFHPQGSRSHLTIQS
                     VGKEILPFIDSTFSTLKVGNARLLVGDSLAGSIALLTALTYPTIFSRVAMLSPHSDDK
                     VLDKLNQCANKEQLTIWHVIGLDEKDFTLPTNGKRADFLTPNRELAEQIKKYNITYYY
                     DEFEGGHQWKDWKPLLSDILLYFLRKNTDDQHYE"
     gene            2751..3260
                     /locus_tag="RFE25_001185"
     CDS             2751..3260
                     /locus_tag="RFE25_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcG family protein"
                     /protein_id="HDU2816259.1"
                     /translation="MILGLALIPSKSFQEAVDSYRKRYDKQYSRIKPHVTIKAPFEIE
                     DGDLDSVIEQVRARINGIPAVEVHATKASSFKPTNNVIYFKVAKTDDLEELFNRFNGE
                     DFYGEAEHVFVPHFTIAQGLSSQEFEDIFGQVALAGVDHKEIIDELTLLRFDDDEDKW
                     KVIETFKLA"
     gene            complement(3373..4563)
                     /locus_tag="RFE25_001186"
     CDS             complement(3373..4563)
                     /locus_tag="RFE25_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2816260.1"
                     /translation="MQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVT
                     SIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPAS
                     PFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIK
                     VHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGIL
                     LQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFM
                     YGVILSGFILYMILIFTLSMIVNIHIVWIIALAIGLMYGILLPAWNTFMARFIKSDEQ
                     EETWGVFNSIQGFGSMIGPLFGGLITQFTNDLNNTFYFSALIFLVLAVFYGSYFIANR
                     EKAK"
     gene            complement(4541..5716)
                     /locus_tag="RFE25_001187"
     CDS             complement(4541..5716)
                     /locus_tag="RFE25_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diglucosyl diacylglycerol synthase"
                     /protein_id="HDU2816261.1"
                     /translation="MVTQNKKILIITGSFGNGHMQVTQSIVNQLNDMNLDHLSVIEHD
                     LFMEAHPILTSICKKWYINSFKYFRNMYKGFYYSRPDKLDKCFYKYYGLNKLINLLIK
                     EKPDLILLTFPTPVMSVLTEQFNINIPVATVMTDYRLHKNWITPYSTRYYVATKETKQ
                     DFIDVGIDPSTVKVTGIPIDNKFETPINQKQWLIDNNLDPDKQTILMSAGAFGVSKGF
                     DTMITDILAKSANAQVVMICGKSKELKRSLIAKFKSNENVLILGYTKHMNEWMASSQL
                     MITKPGGITITEGFARCIPMIFLNPAPGQELENALYFEEKGFGKIADTPEEAIKIVAS
                     LTNGNEQLTNMISTMEQDKIKYATQTICRDLLDLIGHSSQPQEIYGKVPLYARFFVK"
     gene            6149..7633
                     /locus_tag="RFE25_001188"
     CDS             6149..7633
                     /locus_tag="RFE25_001188"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HDU2816262.1"
                     /translation="MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVG
                     YTVDSHKFCQNVADQGCKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQ
                     LVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLT
                     KKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHA
                     KSLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESL
                     QGVSFDFVTPFGTYPVKSPYVGKFNISNIMAAMIAVWSKGTSLETIIKAVENLEPVEG
                     RLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQPFVKQKLIFLVGMAGERDLTKTPEMG
                     RVACRADYVIFTPDNPANDDPKMLTAELAKGATHQNYIEFDDRAEGIKHAIDIAEPGD
                     TVVLASKGREPYQIMPGHIKVPHRDDLIGLEAAYKKFGGGPVDQ"
     gene            7614..7874
                     /locus_tag="RFE25_001189"
     CDS             7614..7874
                     /locus_tag="RFE25_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueH family protein"
                     /protein_id="HDU2816263.1"
                     /translation="MALLINKRFIDEGKTIDVYLFEALNNQIIIAIPDWFWSYQMAMT
                     LDEETCFEAILMQLFVFKEEEEAESIASQLTDWIETYKKEKD"
     gene            7874..9436
                     /locus_tag="RFE25_001190"
     CDS             7874..9436
                     /locus_tag="RFE25_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDU2816264.1"
                     /translation="MNLKQEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVK
                     GKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMA
                     VDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLN
                     IETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEENILHLNDDFELEEDHAITNDSAFE
                     QAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSALANFGVQNFLNAYVDFAPMPNARQ
                     TKEDVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQ
                     KITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQTYSFQDLPQFTPEI
                     FMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKN
                     EYNVDVVMEPVGRKIARWIENEDQITDKMNTSRSILVKDRYDDLVFLFENEFATRWFE
                     EKFLEIKLYSLL"
     gene            9738..10541
                     /locus_tag="RFE25_001191"
     CDS             9738..10541
                     /locus_tag="RFE25_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDU2816265.1"
                     /translation="MLMDPSLILPYLWVLVVLVFLEGLLAADNAIVMAVMVKHLPPEQ
                     RKKALFYGLLGAFVFRFLALFLISIIANFWFIQAAGAVYLIYMSIKNLWQFFKHPEIE
                     SPEAGDDHHYDESGEEIKASNKSFWGTVLKIEFADIAFAIDSMLAALAIAVTLPKVGI
                     HFGGMDLGQFVVMFLGGMIGVILMRYAATWFVELLNKYPGLEGAAFAIVGWVGVKLVV
                     MVLAHPDIAVLPEHFPHGVLWQSIFWTVLIGLVIIGWLGSVVKNKKSHK"
     gene            10760..13084
                     /locus_tag="RFE25_001192"
     CDS             10760..13084
                     /locus_tag="RFE25_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDU2816266.1"
                     /translation="MEWTLVDIGKKHVIPKSQYRRKRREFFHNEDREENLNQHQDKQN
                     IDNTTSKKADKQIHKDSIDKHERFKNSLSSHLEQRNRDVNENKAEESKSNQDSKSAYN
                     RDHYLTDDVSKKQNSLDSVDQDTEKSKYYEQNSEATLSTKSTDKVESTEMRKLSSDKN
                     KVGHEEQHVLSKPSEHDKETRIDSESSRTDSDSSMQTEKIKKDSSDGNKSSNLKSEVI
                     SDKSNTVPKLSESDDEVNNQKPLTLPEEQKLKRQQSQNEQTKTYTYGDSEQNDKSNHE
                     NDLSHHTPSISDDKDNVMRENHIVDDNPDNDINTLSLSKIDDDRKLDEKIHVEDKHKQ
                     NADSSETVGYQSQSTASHRSTEKRNISINDHDKLNGQKTNTKTSANNNQKKATSKLNK
                     GRATNNNYSDILKKFWMMYWPKLVILMGIIILIVILNAIFNNVNKNDRMNDNNDADAQ
                     KYTTTMKNANNTVKSVVTVENETSKDSSLPKDKASQDEVGSGVVYKKSGDTLYIVTNA
                     HVVGDKENQKITFSNNKSVVGKVLGKDKWSDLAVVKATSSDSSVKEIAIGDSNNLVLG
                     EPILVVGNPLGVDFKGTVTEGIISGLNRNVPIDFDKDNKYDMLMKAFQIDASVNPGNS
                     GGAVVNREGKLIGVVAAKISMPNVENMSFAIPVNEVQKIVKDLETKGKIDYPDVGVKM
                     KNIASLNSFERQAVKLPGKVKNGVVVDQVDNNGLADQSGLKKGDVITELDGKLLEDDL
                     RFRQIIFSHKDDLKSITAKIYRDGKEKEINIKLK"
     gene            13101..14459
                     /locus_tag="RFE25_001193"
     CDS             13101..14459
                     /locus_tag="RFE25_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDU2816267.1"
                     /translation="MSIFSQFLKRSSPQQGIVLYYIVAIVIAFLLLNLPYVHKPGVEV
                     NPIDTLFVAVSGISVTGLSPISIVDTYSTFGQLIILVILNIGGIGVMAIGTMLWVVLG
                     KHIGIRERQLIMLDNNKNTMSGTVKLIIDIVKSIFVIELVGAMLLAFYFYRDNPDLKY
                     AIMQGVFVSISATTNGGLDITGKSLIPYAHDYFVQAIVIFLIILGSIGFPVLLEVKAY
                     IQNRVTNFRFSLFTKITTSTYLFLFIVGVLAILLFEHNHAFKGLSWHQSLFYSLFQSA
                     TTRSAGLQTIDVTTLSDPTNIIMGILMFIGSSPSSVGGGIRTTTFAILILFLINFSNN
                     ADKTSIKVYNREVHIMDIQRSFAVFTMATILTFLGMLIISATENGKLTFLQVFFEVMS
                     AFGTCGLSLGVTSDISDISKVVLMVLMFIGRVGLISFIIMIAGRREPDKFHYPKERIQ
                     IG"
     gene            14598..16109
                     /locus_tag="RFE25_001194"
     CDS             14598..16109
                     /locus_tag="RFE25_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDU2816268.1"
                     /translation="MEKNENINVEILTTSDMHSHFLNGDYGSNIYRAGTYVNQIRAQN
                     HRVILLDSGGSLAGSLAAYYYAIVAPYKRHPMIKLMNRMHYDASGVSPSEFKFGLSFL
                     TRSIALARFPWLSANIEYNVTKEPYFSTPYCIKHFGDLKIAIVGVTADGLMENEYSEM
                     EQDVSIEKTLVASKRWIRYIHEVEEPDFLIVIYHGGLNKISNSTKNKKASSNEAEKLM
                     EELGVIDLMITAHQHQTIVGQDHETYYVQAGQDAKELVHLSINFKKRTTTYDVESIDS
                     KVIDLNEYEEDQELLDLTFYDRKAVAYWSQEIISDKGLMLSVNGLQDLVCQTHPFSQL
                     LHDAIQLAFDNDITCVHVPMNGEKGLSGQIRNEDLYHAYPYPDKPMDMTISGQNIKDI
                     LEYSYSHLDFVNEQLSLTIIDETLCTMWQGFNYEIDMNQEPGQRVMLDQIDLTKSYRV
                     TMTDYCYRNYKNYLKNAIIHESYDETMSTLIAEKLRDPNYRISCSDNFVVKNR"
     gene            complement(16289..16377)
                     /locus_tag="RFE25_001195"
     tRNA            complement(16289..16377)
                     /locus_tag="RFE25_001195"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16340..16342),aa:Ser,seq:gct)
     gene            complement(16380..16454)
                     /locus_tag="RFE25_001196"
     tRNA            complement(16380..16454)
                     /locus_tag="RFE25_001196"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16420..16422),aa:Asn,seq:gtt)
     gene            complement(16596..17165)
                     /locus_tag="RFE25_001197"
     CDS             complement(16596..17165)
                     /locus_tag="RFE25_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComK"
                     /protein_id="HDU2816269.1"
                     /translation="MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFK
                     VQKIIERSCKFYGNTYLGKKAETNRITGISSKPPILLTPLFPTYFFPTHSDRQNENIW
                     LNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
                     KNPDQPIDYNKATLNVFEALTRYSLFEDK"
     gene            17375..17593
                     /locus_tag="RFE25_001198"
     CDS             17375..17593
                     /locus_tag="RFE25_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HDU2816270.1"
                     /translation="MKYNTNVKHTTLEAFVTTVNDLGIELIINEALREVRKRQLIELI
                     DDALVNKDEAAFNQYTAEYKNLEAFLGE"
     gene            complement(17674..18660)
                     /locus_tag="RFE25_001199"
     CDS             complement(17674..18660)
                     /locus_tag="RFE25_001199"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDU2816271.1"
                     /translation="MKFISNNNITDPTLNLAMEEYVLKNLPAEESYFLFYINRPSIIV
                     GKNQNTIEEVNQTYIDAHNIDVVRRISGGGAVYHDTGNLNFSFITDDDGNSFHNFQKF
                     TEPIVQALQSLGVNAELTGRNDIQVGQAKISGNAMVKVKNRMFSHGTLMLNSDLDEVQ
                     NALKVNPAKIKSKGIKSVRKRVANIQEFLNDPLEIEEFKKIILKTIFGETEVEEYKLT
                     DEDWENIEKLSNDKYRTWAWNYGRNPKYNFEREEKFEKGFVQIKFDVKRGKIEHAKIF
                     GDFFGVGDVTDLENALVGCLHDFEHIEEALSEYDLYHYFGDIDRHELIRLMS"
     gene            18859..19035
                     /locus_tag="RFE25_001200"
     CDS             18859..19035
                     /locus_tag="RFE25_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkvS family protein"
                     /protein_id="HDU2816272.1"
                     /translation="MTVAEVGNIVEFMDGLRGRVEKINDNSVIVDLTIMENFNDLDLP
                     EKTVINHKRYKIVE"
     gene            19050..19652
                     /locus_tag="RFE25_001201"
     CDS             19050..19652
                     /locus_tag="RFE25_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDU2816273.1"
                     /translation="MNKISKALTWFIISFIIFHLILFIMWGEHQEYWYLYTGIMLIAG
                     ISYVFYQRDIESKRLLTSIGVGIITAIILIMLQLLFSLITSNLSYSSLIKELARTGVN
                     WKWQMLVTLLFVIPCHELYMRTVLQKELTHFSIPKWIAILITAICSSSLFIYLDNWWI
                     VTFIFVAQVILSLSYEYTRRIATTSVAQIVAIILLLIFNA"
     gene            19884..20029
                     /locus_tag="RFE25_001202"
                     /pseudo
     CDS             19884..20029
                     /locus_tag="RFE25_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500662.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
     gene            20568..20669
                     /locus_tag="RFE25_001203"
     CDS             20568..20669
                     /locus_tag="RFE25_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816274.1"
                     /translation="MKFVANKLTLTIIRKFCINNEKEIWIKYEEVFL"
     gene            20679..20951
                     /locus_tag="RFE25_001204"
     CDS             20679..20951
                     /locus_tag="RFE25_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001790097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HDU2816275.1"
                     /translation="MFGTILYLTLALGLSTAAYASTEYAEGGTWSHGVGSKYVWSYYY
                     HGHKGHGATAIGKYRSFSGYTRAGVKAKASATKHNCWVNRAYYNIY"
     gene            20995..22959
                     /locus_tag="RFE25_001205"
     CDS             20995..22959
                     /locus_tag="RFE25_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HDU2816276.1"
                     /translation="MKWFKLILDVTTFILIAILLFVYTYKENEEILPDTKYPIAVTDW
                     NKKYSKNGIYKRINQFAKNENVAIYKSTSNYTNKNVDKDIYVFNKSKATTITPFNAKY
                     NIHYLSDDELLKKDIKGSYFVKDKNFDVSKFINFLKEYGVTAESYKIDHMMIAVGVIK
                     QMNIEVPLSALLIVYFIYYIFEKNINFKAYAIKYLNGFTLRKIIFENFSKKCTYWVTL
                     IISQILLTTSVLWILNYTGNLDLFILRLVLLSCLFILTISVINLWTFLMLLNLNIANM
                     IKGKQHFKTIRFINTVCKSILLVLIASVMIENTSVIKDLNKIKETEKYWNVLDDYYTI
                     EFAPYHETKQSLIDNMLRSEQLVKASEAENNAILFKPKGDSVDNDNFSPDEGNVILVN
                     NQFWSIYYKQFQPDIPIKNQKNNVEVIIPQKFHAMRNEINQAYHSWFEFVQNKNNKEN
                     KLSIQFINKNDYRIFSFDARDSRHLSFIEAPIIVNVQASDLSNDFYYAMISQGGYLFK
                     NYDALVKNIENYHLDGEISGITNYKDSVMEMYHENNLKLTVLNFSQIIIAIILIIIIL
                     FDVKYYFEQHRKLLVIKKLYGYSTLRANYQYLLINNIVVVFIGILTNVILHSQYIMMI
                     FATILVVQILLQICSLYYHGRRFNEVIKEF"
     gene            22962..23282
                     /locus_tag="RFE25_001206"
     CDS             22962..23282
                     /locus_tag="RFE25_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDU2816277.1"
                     /translation="MKFIIAILLGLIVSITIAFTIIHHPILDRFNPFLKTEYSYAKVP
                     KGTQQYVNITAYSERGEKLDYKLTFNGFSPSRTYVEIKHKGQYVISITYVEKEDIPKE
                     VRQE"
     gene            23279..23920
                     /locus_tag="RFE25_001207"
     CDS             23279..23920
                     /locus_tag="RFE25_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816278.1"
                     /translation="MIELKDLTIQKGNIHILKKLNLKFQCGKSYALIGKSGCGKSTLL
                     NTIAGLEKTGKQYVYFNGQLEQFKSNFYRDKLGYLFQNYGLIDNLTVNENLDIGLAYK
                     KISKKEKEQLKIRYIEQFGLSNSLKRKVHTLSGGEQQRVALIRMMLKDPIVMLADEPT
                     GALDPKTGQMIIQSLFDLVDENKVLILATHDMAIANQCDEIIDLEQYSKVASM"
     gene            complement(24008..24298)
                     /locus_tag="RFE25_001208"
     CDS             complement(24008..24298)
                     /locus_tag="RFE25_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816279.1"
                     /translation="MFYACHFKMKIGGVILTRTYNIIGILSCLISFIIMALPMIWYTA
                     SALWFFPGAIMILLLSLVIVFCYIKTKNQLHLLLIVLNIIILLFFSLPLLLS"
     gene            24439..24576
                     /locus_tag="RFE25_001209"
     CDS             24439..24576
                     /locus_tag="RFE25_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001788572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly(glycerol-phosphate)
                     alpha-glucosyltransferase"
                     /protein_id="HDU2816280.1"
                     /translation="MADKILKLVNNDVLAEEFGSKARENIIEKYSTESILEKWLNLFN
                     S"
     gene            complement(24665..25021)
                     /locus_tag="RFE25_001210"
     CDS             complement(24665..25021)
                     /locus_tag="RFE25_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDU2816281.1"
                     /translation="MKLGMLLIRWMLATSFLVHGTLKFVDLDGTIHFLGSLGLPPTIA
                     VLMSIGEVVGGLALIIGFLTPYVNVFYICVMLGSIFTLKLTRGYVSGYEFEIIHIVMN
                     LACISSYSWKKWLQFY"
     gene            25509..26468
                     /locus_tag="RFE25_001211"
     CDS             25509..26468
                     /locus_tag="RFE25_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDU2816282.1"
                     /translation="MNRNIVKLVVFMLILVVAVAGCGQKDTEEKTEMTTIKDELGTEK
                     IKKNPKRVVVLEYSFADYLAALDMKPVGIADDGSTKNITKSVRDKIGAYESVGSRPQP
                     NMEVISKLKPDLIIADVSRHKKIKSELSKIAPTIMLVSGTGDYNANIEAFKTVAKAVG
                     KEKEGEKRLEKHDKILAEIRKKIEQSTLKSAFAFGISRAGMFINNEDTFMGQFLIKMG
                     IQPEVTKDKTTHVGERKGGPYIYLNNEELANINPKVMILATDGKTDKNRTKFIDPAVW
                     KSLKAVKDNKVYDVDRNKWLKSRGIIASESMAEDLEKIAEKAK"
     gene            complement(26514..26645)
                     /locus_tag="RFE25_001212"
     CDS             complement(26514..26645)
                     /locus_tag="RFE25_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816283.1"
                     /translation="MRYVTMRQFIKRTVKTILVGYVIKFIRNKLSGKSSHPTDNKHN"
     gene            complement(26709..26924)
                     /locus_tag="RFE25_001213"
     CDS             complement(26709..26924)
                     /locus_tag="RFE25_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HDU2816284.1"
                     /translation="MKVNKAIYVIVALFLGGLGIHKFYADKFGQGLFHLLFFWTGIPT
                     IISIIHAIFVIFTKKADKDGYIIFPKN"
     gene            27089..27640
                     /locus_tag="RFE25_001214"
     CDS             27089..27640
                     /locus_tag="RFE25_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2816285.1"
                     /translation="MIRQARPEDRFDIAKLVYMVWDDMELELVKHLPKDMVLDAIEKS
                     CVDATYRTFYQHILVYEVENKVAGCIISYSGENELKYEKAWELLDLPEEIKQYGTPLP
                     VKEAKDDEYYIETIATFAAYRGRGIATKLLTSLLESNTHVKWSLNCDINNEAALKLYK
                     KVGFISDGQIELYKHMYHHLIVK"
     gene            complement(27692..28630)
                     /locus_tag="RFE25_001215"
     CDS             complement(27692..28630)
                     /locus_tag="RFE25_001215"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDU2816286.1"
                     /translation="MSNQYQQYSTVKKYWHLMRPHTLTASVVPVLVGTAASKIYFLGS
                     EDHIKISLFIAMLLACLLIQAATNMFNEYYDYKKGLDDHESVGIGGAIVRNGMSPELV
                     LRLAIAFYILAAILGLFLAANSSFWLLPVGLVCMAVGYLYTGGPFPISWTPFGELFSG
                     VFMGMFIIVIAFFIQTGNIQSYVIWLSVPIVITIGLINMANNIRDRVKDKASGRKTLP
                     ILLGKNASLTFMAIMYFIAYAFIVLTIIIKPGGSLFYLLALLSFPMPVKVIRRFKKND
                     TPPTMMPAMAAAGKTNTFFGLLYALGIYISALFAGI"
     gene            28812..30173
                     /locus_tag="RFE25_001216"
     CDS             28812..30173
                     /locus_tag="RFE25_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000190617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HDU2816287.1"
                     /translation="MATGVLEDDIVKEIYGSSKEWVSVEVKLSQSLDPSTLFHLTDNE
                     AGDRFYMRLNDNRTSYFGYKAIQLFKNNSKNKQSIFKDWEKLKHNITFIHPQSEKHHL
                     RVVGGFQFSSHKSDDEWREFGLNHFVLPEVLISTDNNGTFLTYTVKRESFTVEALNDL
                     MDLFNNISDIDVDEQIGEITRNEDIYKDDWRQLVVEAIESINNEEKIVLARRRLIKFD
                     KDISIPYILKQAYSKEKNSYIFLLESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKR
                     SQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYH
                     LYTEIKAPLKDDSYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYID
                     IYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGVDMN
                     GKS"
     gene            30160..31833
                     /gene="menD"
                     /locus_tag="RFE25_001217"
     CDS             30160..31833
                     /gene="menD"
                     /locus_tag="RFE25_001217"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HDU2816288.1"
                     /translation="MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEA
                     HPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLI
                     VLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETINAIYYQMQIASQY
                     LYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGL
                     IIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVD
                     FVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLME
                     DTTINRVSWLEKWQCLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMP
                     IRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLM
                     SKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFK
                     RFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL"
     gene            31820..32623
                     /gene="menH"
                     /locus_tag="RFE25_001218"
     CDS             31820..32623
                     /gene="menH"
                     /locus_tag="RFE25_001218"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HDU2816289.1"
                     /translation="MTHYKYYEANVETNQVLVLLHGFLSDSRTYYNHIDKYTDICHVI
                     TIDLPGHGEDQSSMDETWNFDYITTLLDRILDKYKDKSITLFGYSMGGRVALYYAING
                     HIPISNLILESTSPGIKEEANQLERRLVDDARAKVLDIAGIELFVNDWEKLPLFQSQL
                     ELPVEIQHQIRLQRLSQSPQKMAKALRDYGTGQMPNLWPRLKEIKVPTLILAGEYDEK
                     FVQIAKKMANLIPNSKCKLISATGHTIHVEDSDEFDTMILGFLKEEQND"
     gene            32616..33437
                     /gene="menB"
                     /locus_tag="RFE25_001219"
     CDS             32616..33437
                     /gene="menB"
                     /locus_tag="RFE25_001219"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HDU2816290.1"
                     /translation="MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAE
                     MIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRL
                     IRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLA
                     RIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALR
                     FLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP"
     gene            complement(33675..34004)
                     /gene="sspC"
                     /locus_tag="RFE25_001220"
     CDS             complement(33675..34004)
                     /gene="sspC"
                     /locus_tag="RFE25_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphostatin B"
                     /protein_id="HDU2816291.1"
                     /translation="MYQLQFINLVYDTTKLTHLEQTNINLFIGNWSNHQLQKSICIRH
                     GDDTSHNQYHILFIDTAHQRIKFSSIDNEEITYILDYDDTQHILMQTSSKQGIGTSRP
                     IVYERLV"
     gene            complement(34042..35223)
                     /gene="sspB"
                     /locus_tag="RFE25_001221"
     CDS             complement(34042..35223)
                     /gene="sspB"
                     /locus_tag="RFE25_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease staphopain B"
                     /protein_id="HDU2816292.1"
                     /translation="MNSSYKSRVFNIISIIMVSMLILSLGAFANNNKAKADSHSKQLE
                     INVKSDKVPQKVKDLAQQQFAGYAKALDKQSNAKTGKYELGEAFKIYKFNGEEDNSYY
                     YPVIKDGKIVYTLTLSPKNKDDLNKSKEDMNYSVKISNFIAKDLDQIKDKNSNITVLT
                     DEKGFYFEEDGKVRLVKATPLPGNVKEKESAKTVSAKLKQELKNTVTPTKVEENEAIQ
                     EDQVQYENTLKNFKIREQQFDNSWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSE
                     QDLPNCSTFPNQMIEYGKSQGRDIHYQEGVPSYEQVDQLTKDNVGIMILAQSVSQNPN
                     DPHLGHALAVVGNAKINDQEKLIYWNPWDTELSIQDADSSLLHLSFNRDYNWYGSMIG
                     Y"
     gene            complement(35305..36351)
                     /gene="sspA"
                     /locus_tag="RFE25_001222"
     CDS             complement(35305..36351)
                     /gene="sspA"
                     /locus_tag="RFE25_001222"
                     /EC_number="3.4.21.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu-specific serine endopeptidase SspA"
                     /protein_id="HDU2816293.1"
                     /translation="MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQS
                     SKQQTPKIKKGGNLKPLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTF
                     IASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG
                     DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKI
                     TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQ
                     NIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDNPNNPDNPNNPDEPNNPDNPNNPDNP
                     DNGDNNNSDNPDAA"
     gene            complement(36879..38033)
                     /locus_tag="RFE25_001223"
     CDS             complement(36879..38033)
                     /locus_tag="RFE25_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDU2816294.1"
                     /translation="MKLSLNSNSKYLRAPSIRQFSNRMNNLDDCVNLTIGQPDFPMPD
                     VVKKAYIDAINNDKTSYSHNKGLLETREAISQYFKNRYHFSYDPEEIIVTNGASEAID
                     TTLRSIIEPGDEIIIPGPIYAGYIPLIEVLGGKPIYIDTTATQFKITPDALESHISPK
                     TKAVLLNYPTNPTGVVLKRNEVLNIVNVLKKYPIFIISDEIYAENTFSGKHVSFAEFE
                     DIRDQLILIGGLSKSHSATGIRIGFLLGPQYLIDKLTFMHAYNCICANVPAQIACITA
                     LNEGLEAPKYMNEAYVERRNYLVSELTKLGFEITAQPEGAFYIFPSIKHITDDDFEFC
                     VDLLESTHLAIVPGSSFTEFGKGFVRISYAYEMDVLKEGMKRLAKYLNTK"
BASE COUNT        13486 a         5285 c         6735 g        12647 t
ORIGIN      
        1 ttataagaat attctgaaaa atatattgaa gtgtctcgtg cttaatcgta taatattttt
       61 atgtttaaac aataggggga atcttatgat tgaaaaatta gtaacctttt taaatgaggt
      121 tgtttggagt aagccattag tttatggttt gctaattact ggtgtgctat ttacattgcg
      181 tatgcgattt tttcaagtta gacattttaa agaaatgatt cgattaatgt ttcaaggaga
      241 gaagtctcct aatggtattt caagttttca agcgatagcc atgtctttag caggcagggt
      301 tggtacaggt aatattgtcg gtgtatctac tgcaatattt ataggaggac ctggtgcagt
      361 attttggatg tggattactg cgtttttagg tgcaagtagt gcttttattg aatctacact
      421 tggtcaaata ttcaagagag ttgaaaataa tgaataccgt ggtggaccag cgtattatat
      481 tgaatatggt attggtggta aatttggtaa aatttacgga attatctttg ctattgttac
      541 gattatctca gtaggtctat tgcttcctgg tgtgcaatct aacgctatag caagttctat
      601 gcataatgcg attcatgttc cacaatggtt aatgggtgct attgttgtag ttattttggg
      661 attaattatt tttggtggtg tacgtagtat tgccaatgtt gcaacagccg ttgtaccatt
      721 tatggcaatt atttacatac tgatggctgt cattatcatt tgtatcaata tacaagaagt
      781 gccagcgtta tttgcattaa ttttcaaatc agcatttgga ttacaatctg cttttggtgg
      841 tatcgttggc gcaatgatag agattggtgt taaacgtgga ttatactcaa atgaggctgg
      901 tcaaggtaca ggtccacacg cagcagcggc agcagaagta tcacatccaa gtaaacaagg
      961 tctagtacaa gcattttcag tttatattga tacattattt gtatgtactg caactgctct
     1021 gattatactt atttctggta catataatgt gactgatggt acggttaatg cgaatggcac
     1081 accgcattta attaaagatg gcggtattta tgttgaaaat gcaacaggta aagattattc
     1141 aggtactgcg atgtatgcac aagccggcat tgataaagcg ttccatggca gtggttatca
     1201 atttgatcct actttctctg gcgtaggttc gtactttatt gcatttgctt tattcttctt
     1261 tgcatttact acaattttgt cgtactacta cattacagaa acaaatgttg cttatttaac
     1321 gcgtaatcaa aataatcaag tttcatcgat atttattaat attgctcgtg tgattatttt
     1381 gttcgctaca ttttacggtg cagttaaaac agctgatgta gcatgggcat tcggtgattt
     1441 aggtgtaggt ctaatggctt ggttaaatat cattgcgatt tggattttac ataagcctgc
     1501 cgtaaatgct ttaaaagatt atgaaattca aaagaaacgt ttaggaaacg gttataatgc
     1561 agtttatcaa cctgatccga ataaattacc taatgctgtc ttttggttga agacatatcc
     1621 agaacgttta aaacaagcac gtgccaaaaa gtaatctact tttgtttata gtatatgtag
     1681 tgatcatttg ataaaaaaag aaacagcatt gataatttta ggtgctcaga aatttgaatt
     1741 ttaaaaatat agtgtctctt ggtacaataa caatacaact actagggggc acttttttat
     1801 gtcagaattt aaaactggta agattaataa acatgtttta tatagtaata ttttaaatag
     1861 agatgtcacg ataagtattt atttaccaga atcttataat caacttgtta aatataatgt
     1921 cattctttgc tttgacggat tagatttttt acgtttcggg agaatacaac gtacatatga
     1981 atcgttaatc aaagaagcgc gtattgatga tgcgatcatt gttggattcc attatgaaga
     2041 cgttgataag cgtagagagg aatttcatcc acaaggaagt cgttctcatt taactattca
     2101 atcagtcggt aaagaaatat tgccatttat tgactcgacg ttttctacac tgaaagtagg
     2161 taatgcaagg ttattagtag gggatagttt agcgggtagt attgccttat taacggcgtt
     2221 gacctatcca acgattttta gtcgtgtagc aatgttaagt ccacattcag atgacaaagt
     2281 attagataag ctaaatcaat gtgctaataa agaacaattg acaatttggc atgtcattgg
     2341 tctagatgaa aaagatttta ctttaccaac aaatggtaag cgtgccgatt tcttaacacc
     2401 gaatagagaa ttagctgaac aaattaagaa atataatata acttattatt acgatgaatt
     2461 tgaaggtggt caccaatgga aagattggaa accattgctg tcagatatat tattgtattt
     2521 tttacgtaaa aacacagatg atcaacatta tgagtaattt acattagtag atttagtatg
     2581 aattgtcttc atatagtttg gtctataata taatttataa aagattttac tgtttgattt
     2641 aatttaaatt tgtcgaaatt gcaaaagatg tataatgaat tatttttaat gtaacggttt
     2701 tcaaagaaat ttgatataat agcaataggt taaacaaagg aggaattcag atgattttag
     2761 gattagcatt aattccatca aagtcatttc aagaagcggt ggattcttac cgtaaaagat
     2821 atgataaaca gtattcacga attaaaccac atgtgacaat taaagcgcca tttgaaattg
     2881 aagatggtga tttagattct gtcattgaac aggttagagc tcgtattaat ggtataccag
     2941 cagtagaagt tcatgctaca aaagcttcta gcttcaaacc aacgaacaat gtgatttact
     3001 ttaaagttgc gaagacggac gacttagaag aattgtttaa tcgctttaat ggagaagatt
     3061 tctatggaga agctgaacat gtttttgtgc cacactttac aatagcacaa ggactatcta
     3121 gccaagaatt cgaagatatt tttggtcaag tagcattagc tggggtagac cataaagaaa
     3181 ttatcgatga attaactttg ttacgttttg acgatgacga agataaatgg aaagttattg
     3241 aaacgtttaa attagcttaa gtaacataat agtattgtta atcgtagtat gtttgaatta
     3301 ataagaaaat ggtcattttt attgaatgta ataaaaatga ccattttctt tattttaaaa
     3361 tacgttttaa ccttacttag ctttttctct atttgctata aagtagcttc cataaaatac
     3421 agctaagact aaaaagatta atgccgagaa ataaaatgta ttgtttaaat cgttggtaaa
     3481 ttgtgtaatt aatccgccaa ataatggccc tatcattgag ccgaatcctt ggatactatt
     3541 aaaaacaccc caagtttctt cttgttcatc tgatttgata aatcgtgcca taaaggtatt
     3601 ccatgctggt aataagatgc catacattag accgatagct aaagcgataa tccacacgat
     3661 gtgaatatta acaatcatag atagagtaaa aattaatatc atgtataaaa taaatccgct
     3721 tagaataaca ccatacataa agtttctgct gcggttatct attagtttcg ataaaaatag
     3781 catcgaaact gcacagccga taccaccaat aatgattgca acagtatatt caattgtgct
     3841 tacgttaata accttagtag catatgttgg taatatagga actagggcag caattgcggc
     3901 accttgtaaa agaataccag ggaacaacaa taaatggcgc tttgtcacat caacaatttg
     3961 tctcaattga gctttaactg gacgagtatt ataatttgtt aactttacat cgacaaaata
     4021 atataatatc catgcaatta aaacgactaa agacatcatg aaggcaaagc gtgttgggtg
     4081 cactttgata agtagattca taaaaaccat acctaccaat aggcctaaca accatgaaaa
     4141 ataaacatag cccatttgtt tgccacgttt atcttcttca acactggata acataatgac
     4201 ccaaatagga ctaactgcaa taccgagcat catagcacta aatatgatta caaaaggtga
     4261 tgctggaaac caaataacta aaaataaact tgtaaatgct aaaataaatc cagtcgttaa
     4321 aacgattttt gtgccgaatt ttttcagtaa aaatcctata acaaagtttg tagatgcatc
     4381 agcaataaaa tgtattgaaa atgctagaga cgttattgct acagcaatgg atgtaactgt
     4441 tggcaagaaa ttaatatagc ttaggatata catgcctctc gcaaattcca ttaaaaataa
     4501 gataataagc attaaaatga aatttttatg attagcgtaa ttatttaacg aagaatcttg
     4561 catataaagg aacctttcca taaatctctt gtggttgtga tgaatgaccg attaaatcaa
     4621 gtaagtctcg acatattgtc tgtgtagcat acttaatttt atcttgttcc attgtactaa
     4681 tcatgttagt taattgctca ttaccgttcg ttaaacttgc tacaattttt attgcttctt
     4741 ctggagtatc agcgatttta ccaaaacctt tttcttcaaa gtaaagggca ttttcaagct
     4801 cttgaccagg tgcaggattt aggaaaatca ttggaataca acgggcgaaa ccttcagtta
     4861 ttgtgatacc accaggtttc gtaatcataa gttgacttga tgccatccat tcattcatgt
     4921 gtttggtata acctagaatc aatacattct cgttagattt aaacttagct attaaagaac
     4981 gctttagctc tttgctctta ccacaaatca taactacttg tgcatttgca cttttcgcta
     5041 atatatcagt aatcatcgtg tcaaaacctt tagatacacc aaatgcacca gctgacatta
     5101 aaatagtttg cttatctgga tctaagttgt tgtctattaa ccactgcttt tgattaatag
     5161 gcgtttcaaa tttgttatca ataggaatac ctgtcacttt aactgttgaa ggatcaatac
     5221 ctacgtctat gaagtcttgt ttcgtttctt ttgttgccac ataatatctt gttgaatacg
     5281 gcgtaatcca gtttttatgt aagcgatagt ctgtcatcac tgtagcaact ggaatattaa
     5341 tgttaaattg ctcagttagt accgacataa ctggtgtagg aaacgttaat aatattaaat
     5401 ctggcttttc ttttatcaat aaattaatta acttattaag tccatagtat ttgtaaaaac
     5461 atttgtctag tttatctggg cggctgtaat aaaacccttt gtacatattt ctaaaatatt
     5521 taaagctatt gatataccat tttttacaaa tagaagtcaa aattggatga gcttccataa
     5581 ataaatcgtg ctcaatgacg cttaaatggt ctagattcat atcattaagt tgattaacga
     5641 tactctgtgt aacttgcata tgaccgttac cgaatgagcc agtaataatc aatatctttt
     5701 tattttgagt aaccattaat agccaccctc cgttagtttg aaaattttat ttaagtgtaa
     5761 cttattttac ggcattataa aagaaataaa gacgcaaagt cgttacattt atagcaattt
     5821 taatcaatag atgaattgat acaaaataaa acgttatttt ataaagcaat ttattgttct
     5881 atgttttatt tgtatattta aaattatcca gtatacaatt atagcatatt tttggaaaca
     5941 attatgatat tataccatgt tacaagatgg ttttaataat ttaagatgag ccataattgt
     6001 aaaactaatt cataataccg tatgttttat ttttaatagt agaaattaga aaatgctgat
     6061 tagtaggata taacagtgaa attataaatt tattaacatc aacaaaacgt gtataataaa
     6121 catattgtag aaaaaggagc ggttcagttt ggatgcaagt acgttgttta agaaagtaaa
     6181 agtaaagcgt gtattgggtt ctttagaaca acaaatagat gatatcacta ctgattcacg
     6241 tacagcgaga gaaggtagca tttttgtcgc ttcagttgga tatactgtag acagtcataa
     6301 gttctgtcaa aatgtagctg atcaagggtg taagttggta gtggtcaata aagaacaatc
     6361 attaccagct aacgtaacac aagtggttgt gccggacaca ttaagagtag ctagtattct
     6421 agcacacaca ttatatgatt atccgagtca tcagttagtg acatttggtg taacgggtac
     6481 aaatggtaaa acttctattg cgacgatgat tcatttaatt caaagaaagt tacaaaaaaa
     6541 tagtgcatat ttaggaacta atggtttcca aattaatgaa acaaagacaa aaggtgcaaa
     6601 tacgacacca gaaacagttt ctttaactaa gaaaattaaa gaagcagttg atgcaggcgc
     6661 tgaatctatg acattagaag tatcaagcca tggcttagta ttaggacgac tgcgaggcgt
     6721 tgaatttgac gttgcaatat tttcaaattt aacacaagac catttagatt ttcatggcac
     6781 aatggaagca tacggacacg cgaagtcttt attgtttagt caattaggtg aagatttgtc
     6841 gaaagaaaag tatgtcgtgt taaacaatga cgattcattt tctgagtatt taagaacagt
     6901 gacgccttat gaagtattta gttatggaat tgatgaggaa gcccaattta tggctaaaaa
     6961 tattcaagaa tctttacaag gtgtcagctt tgattttgta acgccttttg gaacttaccc
     7021 agtaaaatcg ccttatgttg gtaagtttaa tatttctaat attatggcgg caatgattgc
     7081 ggtgtggagt aaaggtacat ctttagaaac gattattaaa gctgttgaaa atttagaacc
     7141 tgttgaaggg cgattagaag ttttagatcc ttcgttacct attgatttaa ttatcgatta
     7201 tgcacataca gctgatggta tgaacaaatt aatcgatgca gtacagcctt ttgtaaagca
     7261 aaagttgata tttttagttg gtatggcagg cgaacgtgat ttaactaaaa cgcctgaaat
     7321 ggggcgagtt gcctgtcgtg cagattatgt cattttcaca ccggataatc cggcaaatga
     7381 tgacccgaaa atgttaacgg cagaattagc caaaggtgca acacatcaaa actatattga
     7441 atttgatgat cgtgcagaag ggataaaaca tgcaattgac atagctgagc ctggggatac
     7501 tgtcgtttta gcatcaaaag gaagagaacc atatcaaatc atgccagggc atattaaggt
     7561 gccacatcga gatgatttaa ttggccttga agcagcttac aaaaagttcg gtggtggccc
     7621 tgttgatcaa taaaagattt attgatgaag gtaaaactat tgatgtttat ttattcgaag
     7681 cattaaataa ccagataatc attgctatac cagattggtt ttggtcatat cagatggcaa
     7741 tgacattaga tgaagaaact tgttttgaag caatactcat gcaattgttt gtttttaaag
     7801 aagaggaaga ggcagaatcg attgcatcac aactaacaga ttggatagaa acatataaaa
     7861 aggagaaaga ctaatgaact taaagcaaga agttgagtct agaaagactt ttgcgattat
     7921 ttcacatccc gatgcaggga aaacaacgtt aactgaaaaa ctattgtact tcagtggtgc
     7981 tattcgtgaa gcgggtacag ttaaagggaa gaagactggt aaatttgcga caagtgactg
     8041 gatgaaagtt gaacaagagc gtggtatttc tgtaactagt tcagtaatgc aatttgatta
     8101 cgatgattat aaaatcaata tcttagatac accaggacat gaagactttt cagaagatac
     8161 gtatagaaca ttaatggcag ttgacagtgc tgtcatggtc atagactgtg caaaaggtat
     8221 tgaaccacaa acattgaagt tatttaaagt ttgtaaaatg cgtggtattc caatctttac
     8281 attcattaat aaattagacc gagtaggtaa agaaccattt gaattattag atgaaatcga
     8341 agagacatta aatattgaaa cataccctat gaattggcca attggtatgg gacaaagttt
     8401 ctttggcatc attgatagaa agtctaaaac aattgaacca tttagagatg aagaaaatat
     8461 attacatttg aatgatgatt ttgagttgga agaagatcat gcaattacaa atgatagtgc
     8521 ttttgaacaa gcgattgaag aattaatgtt ggttgaagaa gcgggtgaag cctttgataa
     8581 tgacgcgctg ttgagtggag acttaacacc tgtatttttc ggttcagctt tagctaactt
     8641 tggtgtacaa aatttcttaa atgcatatgt tgattttgcg ccaatgccaa atgcgagaca
     8701 aacaaaagaa gacgttgaag taagcccgtt tgatgattca ttttcaggat ttatctttaa
     8761 aattcaagcc aacatggacc ctaaacaccg tgatagaatt gcctttatgc gtgtcgttag
     8821 tggtgcattt gaacgtggta tggatgttac tttgcaacgt actaataaaa agcaaaagat
     8881 cacacgttca acgtcattta tggcagacga taaagaaact gtgaatcatg ctgtagcagg
     8941 cgatatcatt ggactatatg atactggtaa ttatcaaatt ggagatactt tagttggtgg
     9001 aaaacaaacc tacagtttcc aagatttacc acaatttacg ccagaaattt ttatgaaagt
     9061 ttctgctaaa aacgtcatga aacagaagca tttccataaa ggtattgaac aattagtaca
     9121 agaaggtgcg attcaatact ataaaacatt acacacaaac caaattattt taggtgctgt
     9181 tggtcagtta caatttgaag ttttcgaaca tagaatgaaa aacgaatata atgttgatgt
     9241 tgttatggag ccagtaggcc gtaaaattgc acgttggatt gaaaatgaag accaaattac
     9301 agataagatg aacacatcaa gatcgatttt agtgaaagat agatatgacg atttagtatt
     9361 cttatttgaa aatgaatttg caacaagatg gtttgaagag aaattccttg aaattaaatt
     9421 gtatagttta ctttaacagc tcaattgtat aatcgaattt gttacattaa aaataattgt
     9481 ttcgttgaag aaaaataaat tgtatatttt aaaagaaaaa ggtatactat gatgtatcaa
     9541 atgaataacc tatggcattt tgtcagaggg gagtaactta agaatcatga ccgtataaat
     9601 gattcgacac tttatcgtca ttacgaagat atcttccggt aaagtgggca atttaaattg
     9661 cttagtgaga cctttgctat ttatttagca taggtctttt tgtttgtact taacttattt
     9721 atttaaagga gttgtacatg ttaatggatc caagtttgat cttaccttat ttatgggtac
     9781 ttgtcgtttt agtattttta gaaggcttat tagcagcaga taacgcgatt gttatggctg
     9841 taatggttaa gcacttacca cccgaacaac gtaaaaaagc tttgttttac ggtttgttag
     9901 gtgcatttgt atttagattt ttagcattat tcttaattag tattatcgcg aacttttggt
     9961 ttattcaagc tgcaggagcg gtttacttaa tttatatgtc aatcaaaaat ctgtggcagt
    10021 tctttaaaca cccagaaatt gaaagtcctg aagctggaga tgatcatcat tatgatgaat
    10081 ctggtgaaga gattaaagca agtaacaaat cattctgggg aactgtgttg aaaatagaat
    10141 ttgcagatat cgcatttgcc attgattcta tgcttgctgc tttagctatt gctgtaacac
    10201 ttcctaaagt tggtattcac tttggtggta tggacttagg tcagttcgta gtcatgttcc
    10261 taggtggaat gattggtgtt attctaatgc gttatgcagc aacatggttt gtagagctat
    10321 taaacaaata tccaggactt gaaggtgcag ccttcgcgat cgttggttgg gtaggtgtta
    10381 aattagttgt catggtatta gcgcacccag acatcgctgt attgcctgag cacttcccac
    10441 atggcgtatt atggcaatct attttctgga cagtactaat tggattagta attatcggtt
    10501 ggttaggttc agttgttaaa aataaaaaat cgcataaata attgatgtga agcggacaat
    10561 cttaatttag tttaaggttg tcctttttca tttaattgag tgatttatga aaaatggatt
    10621 ttgaagaatg tgaatcaaaa gatgcgatat agtattaaga aaatgtgcct tttatattta
    10681 gcattttttc aatagaaatt atatagattt taaagcaaat taggtgttaa tgtgtcataa
    10741 tgataagtga ttttattgaa tggagtggac attagtggat attggtaaaa aacatgtaat
    10801 tcctaaaagt cagtaccgac gtaagcgtcg tgaattcttc cacaacgaag acagagaaga
    10861 aaatttaaat caacatcaag ataaacaaaa tatagataat acaacatcaa aaaaagcaga
    10921 taagcaaata cataaagatt caattgataa gcacgaacgt tttaaaaata gtttatcatc
    10981 gcatttagaa cagagaaacc gtgatgttaa tgagaataaa gctgaagaaa gtaaaagtaa
    11041 tcaggatagt aagtcagcat ataacagaga tcattattta acagacgatg tatctaaaaa
    11101 acaaaattca ttagattcag tggaccaaga tacagagaaa tcaaaatatt atgagcaaaa
    11161 ttctgaagcg actttatcaa ctaaatcaac cgataaagta gaatcaactg aaatgagaaa
    11221 gctaagttca gataaaaaca aagttggtca tgaagagcaa catgtacttt ctaaaccttc
    11281 agaacatgat aaagagacta gaattgattc tgagtcttca agaactgatt cagacagctc
    11341 gatgcagaca gagaaaataa aaaaagacag ttcagatgga aataaaagta gtaatctgaa
    11401 atctgaagta atatcagaca aatcaaatac agtaccaaaa ttgtcggaat ctgatgatga
    11461 agtaaataat cagaagccat taactttacc ggaagaacag aaattgaaaa gacagcaaag
    11521 tcaaaatgag caaacaaaaa cctatacata tggtgatagc gaacaaaatg acaagtctaa
    11581 tcatgaaaat gatttaagtc atcatacacc atcgataagt gatgataaag ataacgttat
    11641 gagagaaaat catattgttg acgataatcc tgataatgat atcaatacac tatcattatc
    11701 aaaaatagat gacgatcgaa aacttgatga aaaaattcat gttgaagata aacataaaca
    11761 aaatgcagac tcgtctgaaa cggtgggata tcaaagtcag tcaactgcat ctcatcgtag
    11821 cactgaaaaa agaaatattt ctattaatga ccatgataaa ttaaacggtc aaaaaacaaa
    11881 tacaaagaca tcggcaaata ataatcaaaa aaaggctaca tcaaaattga acaaagggcg
    11941 cgctacgaat aataattata gtgacatttt gaaaaagttt tggatgatgt attggcctaa
    12001 attagttatt ctaatgggta ttattattct aattgttatt ttgaatgcca tttttaataa
    12061 tgtgaacaaa aatgatcgca tgaatgataa taatgatgca gatgctcaaa aatatacgac
    12121 aacgatgaaa aatgccaata acacagttaa atcggtcgtt acagttgaaa atgaaacatc
    12181 aaaagattca tcattaccta aagataaagc atctcaagac gaagtgggat caggtgttgt
    12241 atataaaaaa tctggagata cgttatatat tgttacgaat gcacacgttg tcggtgataa
    12301 agaaaatcaa aaaataactt tctcgaataa taaaagtgtt gttgggaaag tgcttggtaa
    12361 agataaatgg tcagatttag ctgttgttaa agcaacttct tcagacagtt cagtgaaaga
    12421 gatagctatt ggagattcaa ataatttagt gttaggagag ccaatattag tcgtaggtaa
    12481 tccacttggt gtagacttta aaggcactgt gacagaaggt attatttcag gtctgaacag
    12541 aaatgttcct attgatttcg ataaagataa taaatatgat atgttgatga aagctttcca
    12601 aattgatgca tcagtaaatc caggtaactc gggtggtgct gtcgtcaata gagaaggaaa
    12661 attaataggt gtagttgcag ctaaaattag tatgccaaac gttgaaaata tgtcatttgc
    12721 aatacctgtt aatgaagtac aaaagattgt aaaagattta gaaacaaaag gtaaaattga
    12781 ctatcccgat gtaggtgtta aaatgaagaa tattgccagt ctaaatagtt ttgaaagaca
    12841 agcagttaaa ttgccaggaa aagttaagaa cggtgttgtt gtagatcaag ttgacaacaa
    12901 tggtttagca gatcaatctg gtctgaaaaa aggtgatgta attactgaat tagatggcaa
    12961 acttttagaa gatgatttac gctttaggca gattatattt agtcataaag atgacttgaa
    13021 atcaattaca gcgaagattt atagagatgg taaagagaaa gaaattaata ttaaactaaa
    13081 ataatgttga ggtgaacaac gtgtcaattt ttagccagtt tttaaaaaga tcaagccctc
    13141 aacaaggtat tgtattgtac tatatcgtcg caattgtcat tgcattttta ttattaaact
    13201 taccgtatgt tcataaacca ggtgtagaag taaatccaat tgacacatta tttgttgccg
    13261 tatccggaat tagtgttact ggattgtctc cgataagtat tgtcgatacc tattctacat
    13321 ttggacaatt aattatcctc gtgatattaa atattggtgg aattggcgtc atggcaattg
    13381 gtacgatgtt atgggtggta ctaggtaaac atattggaat tagagaacgt cagttaatta
    13441 tgttagataa taacaaaaac acaatgagtg gtaccgtcaa attgattatt gatattgtaa
    13501 aatcaatatt tgtaatcgaa ctcgtaggag ccatgttatt agcattttac ttttatcgag
    13561 ataatccaga tttaaaatat gcaatcatgc aaggtgtttt tgtttctatt tctgccacta
    13621 ccaatggtgg attagatatt acaggtaagt cattaattcc ttatgcacat gattattttg
    13681 tacaagcgat agttatattt ttaataattt taggatcaat cggcttccca gtattattag
    13741 aagttaaagc ttatattcaa aatagggtta ctaattttag attttcatta tttactaaaa
    13801 ttacgacatc aacatattta ttcctattta ttgttggggt attagccatt ctattatttg
    13861 aacataacca tgcgttcaaa ggtttaagtt ggcatcaatc gttattctat tcgctgtttc
    13921 aatcagcgac tacaagaagt gcgggtcttc aaacaattga tgtgacaaca ctaagtgacc
    13981 ccactaatat tatcatgggt attttaatgt ttataggatc ttcgccaagt tcggttggtg
    14041 gcggtattcg tacaacaact ttcgctattt taattttgtt tttaattaac tttagtaata
    14101 atgccgataa aacatccatt aaagtttaca atagagaagt acacattatg gatattcaac
    14161 gttcatttgc agtatttaca atggcgacaa ttttaacatt tttaggaatg ctaattatat
    14221 cagctactga aaatggtaag cttacatttt tacaagtatt ttttgaagtc atgtctgcat
    14281 ttggaacttg tggactatcg cttggtgtca caagtgatat tagtgatatt tctaaggtcg
    14341 tactaatggt actcatgttt ataggacgtg ttggcttaat atcatttatc attatgatag
    14401 caggacgtcg agaaccagat aaattccatt atccaaaaga acgtattcaa ataggataat
    14461 ataatagcaa tctaagttta gttaatatag attttaactg gaacttagat tgctttttta
    14521 gtttgtattt ttaacttatt ttataagacg attggttttc aaaatggtaa actagtaaca
    14581 atgagaggtg taacatgatg gaaaaaaatg aaaacattaa tgtagagatt ttaactacgt
    14641 cagatatgca tagtcatttc ttaaatggtg attatggttc aaatatttat agagctggta
    14701 cttatgttaa ccaaataaga gcacaaaatc atcgcgtcat tttattagat agtggcggaa
    14761 gtttagctgg ctcgttagcg gcctattatt atgctattgt tgcaccttat aaacgacatc
    14821 caatgataaa gttaatgaac agaatgcatt atgatgctag cggtgtgagt ccaagtgaat
    14881 tcaagtttgg tttatcattt ttaactcgtt caattgcttt ggcacgtttt ccatggttat
    14941 cagcaaatat tgaatacaat gttactaagg agccttattt ttcaactcca tattgtatta
    15001 aacattttgg tgacttaaaa attgctatcg taggcgtcac agcagatggt ttaatggaaa
    15061 atgagtattc tgaaatggag caagatgtat ctattgaaaa gacattagtg gcatcaaaac
    15121 gttggattag atatatccat gaagttgaag agccagattt tttgattgta atttatcatg
    15181 gtggattgaa taaaattagt aatagtacga aaaataaaaa ggcaagttcg aatgaagctg
    15241 aaaaattaat ggaagaactc ggtgttatag atttaatgat tacagctcat cagcatcaaa
    15301 caatagtagg tcaagatcat gaaacgtatt atgttcaggc tggtcaggat gccaaagagc
    15361 ttgtacatct ttcgattaat tttaaaaaga gaacaacaac ttatgatgtt gaaagcattg
    15421 attctaaagt gattgactta aatgagtatg aagaggatca agaattatta gatttaacat
    15481 tctatgatag aaaagcagtg gcttattggt cacaggaaat cataagtgat aaaggtttga
    15541 tgttatcagt gaatgggtta caagatttag tctgtcaaac acatccattt tcgcaattat
    15601 tacatgatgc aattcagctt gcatttgata atgatataac atgtgtccac gtgcctatga
    15661 acggagagaa ggggttgagt ggacagattc gaaatgaaga tttgtatcat gcatacccat
    15721 atccagataa gccaatggat atgacaatta gtggtcaaaa tatcaaagat atattggagt
    15781 atagttattc acatttagat tttgttaacg agcaattaag cttaacaatt attgatgaaa
    15841 cgttatgtac aatgtggcaa ggattcaatt atgagattga tatgaatcaa gaacctgggc
    15901 aacgagtaat gttagatcaa attgatttga ctaagagtta tagagttaca atgactgact
    15961 attgttatcg taactacaag aattatttaa aaaatgctat tatacatgaa tcgtacgatg
    16021 aaacaatgag tacattaatt gcagagaagt taagagatcc gaattatcgt atttcatgta
    16081 gtgataattt tgtagttaaa aacaggtaaa tattgctatg taataaatta attataagtt
    16141 caacaagtat aaaaaccttt cttagagaag attatctagg aaaggttttt agaattttaa
    16201 aattgatata aaagaacagt gaaattctca ttcattatat ataagtaaac aaaaaagcta
    16261 aaatggtata taccatttta gcaagtaacg gaaacggagg gattcgaacc ctcgcgccgc
    16321 tttcgcgacc tacaccctta gcaggggcgc ctcttcagcc aacttgagta cgtttccaat
    16381 ggctccacag gtaggactcg aacctacgac cgatcggtta acagccgata gctctaccac
    16441 tgagctactg tggattaatt tgtatgtgtt tgaatatcaa gcacaaatat tattataaca
    16501 agattaagtt aatttgcaat agatacctta aaaaaatatg cagaacattt acactatatt
    16561 tataaaacat tccgcatatt ttaaaaataa acaatttatt tatcttcaaa taaagaatag
    16621 cgtgtcaatg cttcaaacac attcaatgtg gctttattat aatctattgg ttggtcggga
    16681 ttttttgata tcatgcgaga ttgtttatct accatgtaat agtaaaaaat ggaattgtta
    16741 tattgatgcc ataaactgtg gtatgaaaca tgaagaatga tagattcatt attaataaat
    16801 gtcactttac atttacgatt ttttaattct ttaatacttt cgatataatg catatttaac
    16861 caaatatttt cattttgtct gtcagaatgt gttgggaaaa aataagttgg aaataatggt
    16921 gttagtaaaa taggtggttt actagaaatg ccagtaatgc ggtttgtctc tgctttcttg
    16981 ccaagataag tattaccata aaatttgcaa gagcgttcaa tgattttctg gactttaaaa
    17041 ggattttgaa tacgcgtttt gtcaaaccga attatttcac taccgtttct ttgatcgtca
    17101 tcatcaaatg ctggtcgaat aaccatgtct cctttgcgta tcacataaat attttgagaa
    17161 tacataagca aaacctcgct ttattaagtt ttaaaccatt aatataaaaa tacaattaat
    17221 gatataaaga tattttataa taaaattctg agttgtcaag ttattatttt ggtgaaaatg
    17281 tacaataatt tttaactaat agtcagaata ttcattgatt tcaaaattag aaaaatgtat
    17341 acttattata aattaaagaa aggtagtggt ttctatgaaa tacaatacta atgttaaaca
    17401 tacaacttta gaagcgtttg tcacaactgt caatgatttg ggtattgaat taattatcaa
    17461 tgaagcactt cgagaggtaa gaaaacgaca gctcatagaa cttatagatg acgcactcgt
    17521 caataaagat gaagcagcat ttaatcaata tacggcagaa tacaaaaatt tggaggcatt
    17581 tctcggtgaa taacattgat tcgaattcca taacgcaatc ataaaaggac tattcttaac
    17641 atctcataca tgtaagaata gtcctttaat cgtttatgac attaatctaa ttaattcatg
    17701 tctatctatg tcaccgaaat aatgatataa atcatattct gatagtgctt cttctatgtg
    17761 ctcaaagtcg tgtagacagc caactaatgc attttcaaga tcagtgacat ctccgacacc
    17821 aaagaaatca ccgaaaattt ttgcatgttc gattttacct cgtttaacat caaacttaat
    17881 ttgtacaaat cctttttcaa atttttcctc gcgttcaaag ttatatttag ggtttctacc
    17941 ataattccat gcccaagttc tatatttgtc gttacttaac ttttcaatat tttcccaatc
    18001 ttcatccgtt aatttatatt cttctacttc agtttctcca aagatagttt tcaagatgat
    18061 ttttttaaat tcttcaattt ctaaagggtc atttaaaaat tcttgaatgt ttgctactcg
    18121 tttacgaaca gatttaatac cttttgattt aatcttagct ggattaactt ttagtgcatt
    18181 ctgaacttcg tctaaatcac tatttaacat caacgtacca tgactaaaca ttctattttt
    18241 aactttaacc atagcattcc ctgagatttt cgcttgtcca acttgaatat cgttacgacc
    18301 agttaattca gcatttacgc ctaaagattg taatgcttga acaattggtt cagtgaattt
    18361 ttggaaattg tggaaactgt taccatcatc atctgttata aaactaaagt ttaaattgcc
    18421 agtatcatga taaacagcgc caccaccaga aattcttcta actacatcga tgttatgagc
    18481 atctatatat gtctgattta cttcctctat cgtattttga ttctttccaa caatgataga
    18541 tggtctattt atgtaaaata aaaagtaact ttcttctgct ggtaaatttt ttaaaacata
    18601 ttcttccatt gctaagttta aagttggatc tgtaatatta ttattactaa tgaatttcat
    18661 tacaatctct cccttatatc tatatatatt ctctacttat ttatgcctta actttgctca
    18721 aaatgccaat tatatactca caaatcattc taaatatcgg cttaaagtta cattttatta
    18781 tttttgattg ttaatagttt atttgttaag tgaattttag tacaatataa tttagttatg
    18841 atttaaggag gacttaaaat gactgttgca gaagtgggta acattgttga gtttatggat
    18901 ggattaagag gtcgtgttga aaaaatcaac gataactctg ttattgttga cttaacaatt
    18961 atggaaaatt ttaatgacct tgatttaccg gaaaaaactg ttatcaatca taaacgatat
    19021 aagattgttg aataagaagg taagttataa tgaataaaat ctcgaaggct ttaacttggt
    19081 ttattataag tttcattata tttcatctca tattatttat tatgtggggc gaacaccaag
    19141 aatactggta tttatataca ggtataatgc taattgctgg tatcagttat gtattttatc
    19201 aaagagatat tgaatctaag cggttgctta catcaattgg tgttggtatt attacggcaa
    19261 ttattttaat tatgcttcaa cttttattct cacttataac ttctaattta agttatagtt
    19321 cattaattaa agaattagca agaacaggtg tcaattggaa gtggcaaatg ttagtaactt
    19381 tactttttgt cattccatgt cacgagttat atatgagaac tgttttacaa aaagaattaa
    19441 cacatttttc aataccgaaa tggatagcta tattaataac tgcaatttgt tctagttcat
    19501 tatttattta tttagataat tggtggatag taacatttat atttgttgca caagtgatat
    19561 tatcattaag ttatgagtat actcgacgca tagcaacaac atccgttgcg caaattgttg
    19621 ctattatatt gttattaatt tttaatgctt aaataagctt ttcttagacg tctgtgttct
    19681 aagaaaagct ttttgcttta gaaaagcaat acgaagattc aaggcatgct ttattatagt
    19741 gtatacattt ttaacggcaa gcagttatta ttgaggttat attttagtca gtttttatta
    19801 ctaaatattt tataaaaata gtataatatt ttgtgggcaa gttgaattga tggtggctat
    19861 ctgagtaaag gggggtggta cctatggcat tacttaacac ttttgaaagg aaaagcctat
    19921 tgtgatatct attgcaaacg cattacattt aatgttaagt ttcggtatgt ttatcgtcac
    19981 tttcattggt atagtagtag caataataaa tttaagcaat aaaaaataac catcatttca
    20041 aaactttgac atagaatgat ggttaaagaa aatctcattt agtcaccgtc tttttaacgg
    20101 gctcattagg cgacatgttc ctgcatgtcg tctttttaca tttttatagt aacatatctt
    20161 ttatttaatt gtctattttt attagatgtg taacaaaatt ttgaagtatt ttccgtatat
    20221 tgcctgctaa acatgtcaga tttgaaagga aaatcatact gtggtagaaa tcaattatga
    20281 ttatatggta gtacttataa ataagtgatt tctattgaat atgtaatgaa gttcatatat
    20341 taatataact ttcattgata tagaagtcgc aatgattaat ttaaacaata aaaaacaacc
    20401 atcatttcaa aactttgaca acgaatgatg gttaaagaaa atctcattta gtcaccgtct
    20461 ttttaacggg ttcaataggg gacatgttcc tgcatgtcgt ctatttatgc actgcgcaat
    20521 ttaacaataa tacaattata ctttgatgtc catttaacat aaagtggttg aaatttgtag
    20581 caaataaatt aaccttgact attatcagaa aattctgtat aaataacgaa aaagagatat
    20641 ggattaaata tgaagaggtg tttttataga agaataaaat ttttggcact atattatatt
    20701 taactttagc acttggatta tcaacagcag cttatgcatc tacagaatac gcagaaggag
    20761 gcacttggag tcacggtgtc ggcagtaagt atgtttggtc ttattattat catggtcata
    20821 aaggacatgg tgcaacagct attggaaaat atagatcatt tagtggttat acaagagctg
    20881 gtgtaaaagc aaaagcatca gctactaaac ataattgctg ggtcaataga gcgtattata
    20941 acatttatta aatactaaaa aatcatagaa aataaacaac gcaagaggta caacatgaaa
    21001 tggttcaaat taatacttga tgttacaacc ttcattctga ttgctatatt gttatttgtt
    21061 tatacatata aagaaaacga agaaatattg cctgatacta aataccctat agcggtaact
    21121 gactggaata aaaaatatag taaaaatggg atttataaac gtataaatca attcgctaaa
    21181 aatgagaacg tagcaatcta taaatcaact tcaaattata caaacaaaaa cgtagataaa
    21241 gatatatatg tatttaataa atcaaaagca acaactatca ctccttttaa cgctaaatat
    21301 aacattcatt atttaagtga cgacgaatta ttaaaaaaag atatcaaagg aagttatttt
    21361 gtaaaagaca aaaattttga cgtgtctaaa ttcataaatt ttttaaaaga atatggtgtt
    21421 actgctgaat catacaaaat agatcatatg atgattgccg ttggtgtcat taaacaaatg
    21481 aatatagaag ttccgttatc cgcactttta atcgtttatt ttatttatta tattttcgaa
    21541 aagaacatta atttcaaagc gtatgcgatt aagtatttaa atggttttac attaagaaaa
    21601 ataatttttg aaaatttttc aaaaaaatgc acgtattggg taacgttaat cataagtcaa
    21661 attcttttaa ctacaagtgt actttggata ttaaattaca cgggtaattt agatttattc
    21721 atattaagat tagttctgct ttcatgtctt ttcattttaa cgattagtgt tattaattta
    21781 tggactttct taatgttact aaatttaaat attgctaata tgattaaagg taagcagcac
    21841 tttaaaacaa ttcgttttat taatacagtt tgtaaaagta ttctcttagt actaatagct
    21901 agtgtaatga tagaaaatac tagtgttatt aaagatttga ataaaataaa ggaaactgag
    21961 aaatattgga atgtattaga tgattattac acgattgaat ttgcacctta tcacgaaacg
    22021 aaacaaagtt tgattgataa tatgctgcga tcagaacaat tagtaaaggc tagtgaagca
    22081 gaaaataatg cgattttatt caaaccaaag ggtgactccg ttgacaatga caacttttcg
    22141 cctgatgagg ggaatgtaat attagtaaat aatcagttct ggtcgattta ttacaagcag
    22201 tttcaacctg atattccgat aaaaaatcaa aaaaataatg tcgaagtaat tattccacaa
    22261 aagtttcatg caatgcgtaa tgaaatcaat caagcatatc attcatggtt tgaatttgta
    22321 caaaataaaa ataataaaga gaataagtta tctatacagt ttatcaacaa aaatgattat
    22381 cgaatttttt catttgatgc acgagatagt cgccatttgt catttataga ggcgccaatc
    22441 attgtgaatg ttcaggcatc agatttatcg aatgattttt attatgccat gatcagtcaa
    22501 ggcgggtatt tattcaaaaa ttatgacgcg ctagtaaaaa atattgaaaa ttatcatctt
    22561 gatggggaaa tcagtggaat aaccaattat aaagatagcg tgatggaaat gtatcatgaa
    22621 aacaatttga aattaacagt actcaacttt tcacaaatca ttatcgcaat cattttaata
    22681 attattattt tatttgatgt gaaatattat tttgaacagc atcgaaaatt actcgtaatc
    22741 aaaaagctat atggttattc aacattaaga gccaattacc aatacttatt aataaataat
    22801 atagttgttg tttttattgg aatattgacg aatgtaattt tacattctca gtatataatg
    22861 atgatatttg caacgattct tgtcgttcaa atattattgc agatttgcag cctatactat
    22921 catggccgac gttttaatga agttatcaag gagttttaac tatgaaattt atcattgcaa
    22981 tattattagg attaatcgta tccattacta ttgcttttac aatcatacat catcctatac
    23041 ttgatcgttt taatcctttc ttaaaaacgg agtatagtta tgccaaagtg ccaaaaggta
    23101 cgcaacaata tgttaatatt acggcttata gtgaaagagg ggaaaagctt gattataaat
    23161 taacatttaa tggattttca cctagtagaa cgtatgtcga aataaagcat aaagggcaat
    23221 atgtcatatc gatcacatat gttgaaaaag aggatatacc aaaagaggta agacaagaat
    23281 gatagaatta aaagatttaa ccatacaaaa aggtaatata catattttga agaaacttaa
    23341 tttgaaattt caatgtggaa aatcatatgc acttattggt aaaagtggat gcggtaaatc
    23401 tacattatta aatactattg ctggacttga aaaaacgggg aaacaatatg tctattttaa
    23461 tggtcaatta gaacaattta aatctaattt ttacagagat aaattaggat atttatttca
    23521 aaattatgga ttaatcgata atttgacagt aaatgaaaat ttagatattg gattagcata
    23581 taaaaaaata agtaagaaag aaaaagaaca attaaagata cgttatatag aacagtttgg
    23641 tctgtcaaac agtttaaaaa gaaaagttca tacgctaagt ggaggtgaac aacaacgtgt
    23701 cgctttaatt agaatgatgt taaaagatcc gattgttatg ttagctgatg aaccaacggg
    23761 tgcgttagat cctaaaacag gacagatgat tattcaatca ttatttgatt tggtcgatga
    23821 aaataaagtg ctgattttag caacacatga tatggctatt gcaaatcaat gtgacgaaat
    23881 aatagattta gaacagtata gtaaagtagc atctatgtga tatccaaaag ataaaattaa
    23941 aagccaatca atgggaaatg ttgacttcaa cactccgttt gattggcttt tataatgtgt
    24001 tactaagtta tgaaagtaac aacggtaaac tgaaaaaaag caatataata atatttaata
    24061 cgattagtaa taaatgtaat tgatttttcg ttttaatata gcaaaaaaca atgactaaag
    24121 ataacaacaa tatcatgatt gcacctggga agaaccataa tgctgaagct gtgtaccaaa
    24181 tcattggtaa cgccataata ataaaagata taagacaaga aaggatacca ataatattat
    24241 aagttctagt caaaattaca cctccaattt tcattttaaa atgacatgcg taaaacaatc
    24301 attttaaata catcatacaa taaaattaaa ttgtgcggta gaagaatttg aaattaaatt
    24361 gaattggctt gattaaaagg tgattttata gaagttaata aaaatggtta tttaatagaa
    24421 aaacataata ttaaagacat ggctgataaa atactaaagc ttgttaataa tgatgtttta
    24481 gcagaggagt ttggttcgaa agcgagagaa aacattatag aaaaatattc aacggaatca
    24541 atattagaaa aatggttaaa tcttttcaat agctaaatga aaaaatccta ggtattcatg
    24601 agtacctagg atttttacgc atgatatata caaaaaaaga gaggatagtc ctctcaaata
    24661 atagttaata aaattgtagc catttcttcc agctgtaact actaatacaa gctaagttca
    24721 ttacgatatg tatgatttca aattcataac cacttacata tcctcttgta agtttaagtg
    24781 tgaagattga gcctaacata acacaaatat aaaaaacatt aacataaggc gttaaaaagc
    24841 cgataataag tgctaaacct ccaacaactt caccaattga catcaatact gcgatggtag
    24901 gtggtaaacc taaagagcct aagaagtgaa ttgttccatc taaatcaaca aatttcaaag
    24961 taccatgcac taagaatgat gttgctaaca tccatctaat taaaagcata cctaatttca
    25021 tcatgtcacc tccaacattc atatttttaa aacatagtcc aaattatatt tgtaaacatg
    25081 tggaaagtaa agatttttta taagattaat tattaaatat ttattaaata ttctattgta
    25141 ttgaacaatt gttgtagaaa gatgtttaag tcatcagtta ctttttgtat ttataaataa
    25201 agattagtac agcatagtgc aaagattata gggaaatgaa ttaactattg catcgctatt
    25261 tatgaatcgt aaacactatt atgaaattgc gagagtagta tggataatta gaatgatggt
    25321 ttgagataaa tgagtattat taaccagtgc gtcatcttca aaattagagg ccatttgctg
    25381 tttataataa gaagatttga taataaacta tgataagaaa aaataatagc ataccaaata
    25441 tatcataaac aaattaaatg ataaaataat aatgcagttt tctattaaag ttgtttggag
    25501 gtaaatatgt gaataggaat atcgttaaat tagttgtgtt tatgctaatc ttagttgtag
    25561 cagtagcggg ttgtggtcaa aaagatactg aagagaaaac tgaaatgacg acaataaaag
    25621 atgaattagg aactgaaaaa attaagaaaa atcctaaacg tgttgttgta ttagaatata
    25681 gttttgctga ttatttagca gcattagata tgaaacctgt tggtattgca gatgatggca
    25741 gcactaaaaa tataacaaag tcagtaagag ataagattgg ggcatatgaa tcggttggat
    25801 ctagaccgca accgaatatg gaagtgataa gtaaattaaa accggatttg atcattgcag
    25861 atgttagcag acataagaaa atcaaatcag aattgagcaa aattgctccg acaatcatgt
    25921 tagttagcgg tacgggagat tataatgcaa atattgaagc atttaaaaca gtcgctaaag
    25981 cagtaggcaa agagaaagaa ggcgagaagc gtctggaaaa gcatgataaa atattagcgg
    26041 agattagaaa gaaaattgaa cagagtacgt taaaatctgc atttgcattc ggtatctcaa
    26101 gagcaggtat gtttattaat aatgaagata catttatggg acaattctta attaaaatgg
    26161 gtattcaacc tgaagtcaca aaagacaaaa ctacgcatgt tggtgaacgc aagggtggtc
    26221 cttatatata tttaaataat gaagaacttg ccaatatcaa tccaaaagtt atgattttag
    26281 ccactgacgg aaaaacggac aaaaatagaa cgaaattcat tgatcctgca gtttggaaat
    26341 cattaaaagc tgtgaaagat aacaaagttt atgacgttga ccgaaataag tggttgaaat
    26401 caagggggat tatcgcaagt gaaagtatgg cagaagattt agaaaaaatt gcagaaaaag
    26461 caaaataaaa atacagcgct actcgtaaat catataagag tggcgctgta tttttaatta
    26521 tgtttattat ctgtcggatg tgatgattta cctgaaagtt tatttcgaat aaatttaatt
    26581 acataaccga caaggattgt tttaacagtt cttttaatga attggcgcat cgttacatac
    26641 ctcatttctc tatatcttac gaactatata cccattcata tatgcttttt aaacgtcatt
    26701 gtcacaattt aatttttagg gaatataata taaccatctt tatctgcttt tttagtaaaa
    26761 atgacaaaaa ttgcatgtat tattgagatg atggtaggga tacctgtcca gaaaaataat
    26821 aagtgaaaaa gaccttgtcc aaatttatca gcataaaatt tatgaatacc taaacctcca
    26881 agaaataatg caacaataac ataaatggct ttattgactt tcatttgtaa atcctcctta
    26941 actataattc tacttaaatt cgttgtgaaa accaatattt ctaactttag aattttcaaa
    27001 ctttctaaaa ttataagtat atctttttaa aataagctag aatttctata taataaatgt
    27061 taataacgta aaagggaatg atgacatagt gatacgtcaa gcacgtccag aggaccgatt
    27121 tgatattgcg aagttagttt atatggtttg ggatgatatg gaattagaat tggtaaagca
    27181 tctacctaaa gacatggtat tagatgcaat tgaaaaaagc tgtgttgatg caacatatcg
    27241 aactttttat cagcatattt tagtttatga agtagaaaat aaagtagcag gttgtattat
    27301 tagctatagt ggtgaaaatg aattgaaata cgaaaaagca tgggaactac ttgacttgcc
    27361 agaagaaata aaacaatatg gcacgccatt acctgtaaaa gaagctaaag acgatgagta
    27421 ttatatagaa acaattgcga catttgcagc atatagaggt agaggcatcg cgacaaagtt
    27481 attaacgtca ttacttgaat caaatacaca tgttaaatgg agtttgaatt gcgatattaa
    27541 taatgaagca gcattaaagt tatataaaaa agtaggcttt atatctgatg gacagattga
    27601 attatacaag cacatgtatc atcatttaat tgttaaataa aaaaactcga cagttcgatg
    27661 taagtcgatt gccgagtagt atcattttct attaaatgcc tgcaaataat gcactaatat
    27721 aaatacctaa tgcatataat aaaccgaaaa atgtatttgt tttaccagca gcagccattg
    27781 ctggcatcat tgtaggcggt gtatcattct tcttgaaacg tctgataact ttaacaggca
    27841 ttgggaatga taacaacgca agtaagtaaa ataatgagcc accaggttta ataatgatcg
    27901 taagtacaat aaaggcataa gcgataaagt acatgattgc cataaatgtt aaagaagcat
    27961 ttttacctaa tagaatgggt aaagttttgc gaccacttgc tttatctttg acacggtcgc
    28021 gaatattgtt agccatatta attaaaccga tagtgattac tataggtaca cttaaccaaa
    28081 ttacataact ttgaatattg ccagtttgaa taaagaatgc aataacgata ataaacatac
    28141 ccataaatac gcctgagaat aattcaccga aaggcgtcca tgaaataggg aaagggccac
    28201 ctgtatatag gtaaccaaca gccatacata ctaatccaac tggtaataac caaaatgaag
    28261 agttagcagc taaaaacaaa cctaatattg ctgctaagat gtaaaatgca atggctaatc
    28321 gtagcacaag ctctgggctc ataccgttgc gaacaatggc accaccaatg cctacagatt
    28381 catgatcatc aaggcctttt ttataatcat agtattcatt aaacatatta gttgctgctt
    28441 gaataagtaa gcatgctagt aacatggcaa tgaataggct gattttaata tgatcttcgc
    28501 taccaagaaa atatatttta gatgctgctg taccaactaa aacgggtact acggaagcag
    28561 ttaatgtatg aggacgcatt aaatgccaat atttcttaac tgtagaatat tgctgatatt
    28621 gattactcat tgaatacaaa acctctttaa atcatatttt ttataacaaa gatattttaa
    28681 tagaaagtag cataaaggtc aattgacgtg aaaaattgca agataagttt aagcaattct
    28741 tgtaacacaa ttatccaaaa atgatacaat ataataatga gtgaaaaaag acgaagaaag
    28801 aagtgaaatg gatggctacg ggcgtattag aggacgatat tgtcaaagag atatatggca
    28861 gctcaaagga atgggtttca gttgaagtga aattatcaca gtcactagac ccgagcacat
    28921 tatttcatct cactgacaat gaggcaggag atcgctttta tatgcgtttg aatgataatc
    28981 gaacgtcata ttttggctac aaagcaattc aattattcaa aaataattct aaaaataaac
    29041 aatctatttt taaagactgg gaaaaattaa aacataacat cacatttata catccgcaat
    29101 ctgagaaaca tcatcttcga gttgttggag ggtttcaatt ttcaagtcat aaatcagatg
    29161 atgaatggcg agagtttgga ctaaatcatt ttgtattacc tgaagtttta atttcaactg
    29221 ataataatgg gacattttta acttatacag ttaaaaggga aagttttact gttgaggcat
    29281 tgaacgattt aatggatttg ttcaacaata tatcggatat agatgtggac gagcaaattg
    29341 gggaaattac tagaaatgaa gatatttata aagatgactg gcgtcaactt gtagtagaag
    29401 ctatagaatc tattaataat gaagaaaaaa ttgtactagc acgtagacgg ttaataaagt
    29461 tcgataaaga tatcagtatt ccatatattc taaagcaagc atattctaaa gaaaaaaaca
    29521 gttatatatt cttgttagaa tcacaagatt ctattttctt ttcacaaaca cctgaacaat
    29581 taataaaggt caataataaa atactatcga ctaaagctgt agcaggtaca attaaacgtt
    29641 cacaagatga ggacgaagat acaaaaaatg ttgaagcatt tttaaaagat aataaaaact
    29701 taatcgaaca tcgatttgtt gttgacagta ttttacatga tattaaacct tatatcactg
    29761 aattacatta tgataagacg cctaaaattc taaaaaatga tcatttatat cacttgtaca
    29821 ctgaaataaa ggcgccactg aaggatgatt cgtatattag tttaattgat catttacatc
    29881 caacacctgc tttaggtggc tatccaaaag aatttgcgat ggattttatt gaacagaaag
    29941 aatttggtac acgaggatta tatggtgcgc cggttggcta tatagatata tatgatgatt
    30001 gtgaatttat tgttgcaatt cgttcgatgc ttattaagaa agcacaagca actttatttg
    30061 ctgggtgtgg cattgttaaa gattctgatc cagatagtga attggcagaa acgaacctta
    30121 agttcacacc tatgatgaat gcattaggag tcgatatgaa tgggaaatca taaagcagct
    30181 ttaacgaagc aagtttttac atttgcatct gagttatatg catacggcgt aagggaagta
    30241 gttatcagtc cgggatcacg ctcaacgcca cttgcacttg catttgaagc acatccaaat
    30301 attaaaacat ggatacaccc cgatgagcga agtgcagcat tttttgcagt tgggttaatt
    30361 aaaggcagtg aaagacctgt cgctatatta tgtacgtcag gtacagcagc agcgaattat
    30421 acgcctgcaa ttgctgaaag ccaaattagt agaattccat taatcgtttt aacaagtgac
    30481 cgtccgcatg aattaagaag tgtaggcgca ccacaagcga ttaatcaagt aaatatgttt
    30541 aataattatg taagttatga gttcgatatg cctattgcgg atgatagtaa agagaccatt
    30601 aatgcaattt attatcaaat gcaaattgct agtcaatatt tatatggacc acataaaggg
    30661 ccaattcatt ttaacttgcc atttagagat ccgttaacac ctgatttgaa tgcaacagaa
    30721 ttgttaactt ctgagatgaa gattttaccg cactatcaaa aaagtataga tgcatcggca
    30781 ttaagacaca ttttaaataa gaaaaaaggt ttaattattg taggggatat gcagcaccaa
    30841 gaagttgatc aaatactaac gtattcaacg atatatgatt tgcctatttt agctgatcct
    30901 ttaagtcatt taagaaaatt tgatcatccg aatgttatct gtacatatga tttgctgttt
    30961 agaagcggct tagacttaaa tgtggatttc gtaattcgtg ttgggaaacc agtgatttct
    31021 aaaaagttga atcaatggtt aaagaaaact gatgcatttc aaatattagt gcaaaacaat
    31081 gataagattg atgtctttcc tatagcgcca gatatttcat atgagatttc tgcaaatgat
    31141 ttctttagat cattaatgga agacacgacc atcaatcgcg taagttggtt agaaaaatgg
    31201 caatgcttag agaaaaaagg gcgtaaagaa attaaatgtt atttggaaca agctacagat
    31261 gagagtgcat tcgttggtga attgattaag aaaacatctg aaaaagatgc attatttatt
    31321 agtaatagta tgcctatcag agatgtagat aacttgttat tgaataaaaa tatagatgtc
    31381 tatgcgaatc gtggtgcgaa tggtattgat ggtatcgttt caactgcact gggtatggct
    31441 gtgcataaac gaataacatt attgataggt gatttgtcat tttatcatga tatgaatgga
    31501 ctattaatgt caaaattaaa taatattcag atgaatattg tattattgaa caacgatggt
    31561 ggcggtattt tttcatattt accacaaaaa gaaagtgcaa ctgactattt tgaacggttg
    31621 tttggcacac cgacgggatt ggatttcgag tatacagcta agttatatca attcgatttt
    31681 aaacgtttta acagtgtttc agaatttaaa aatgccacat tgttatctga aacttcgacg
    31741 atttatgaat tgataacgaa tcgcgaagat aactttaaac agcatcaaat tttatatcag
    31801 aaattgagtg aaatgattca tgacacatta taaatactat gaagcaaacg ttgagaccaa
    31861 tcaagtttta gtattactgc atggttttct tagcgacagt cgtacttatt ataatcacat
    31921 cgataaatat actgatatct gtcatgtcat cactatagac ttaccaggcc atggcgaaga
    31981 tcagtcttca atggatgaaa cgtggaattt tgattatatt acgacgttgt tagaccgaat
    32041 tttagataaa tataaagata aatcaataac attgtttgga tattcaatgg gtgggcgtgt
    32101 tgcattatat tatgcaatta atggtcacat ccctatatct aatttgatat tagaaagtac
    32161 gtcaccaggt attaaagaag aagcaaatca attggaacgc cgtcttgttg atgatgcacg
    32221 tgctaaagta ttagacatag caggtattga attatttgtt aatgattggg aaaagttgcc
    32281 attatttcaa tcgcaactag aattaccagt tgaaatacaa catcaaataa gactacaacg
    32341 attgtctcaa tcgccacaga aaatggccaa agcattaaga gattatggta caggtcaaat
    32401 gccaaactta tggccgcgcc tgaaagaaat taaagtacca acattaatat tagctggaga
    32461 atatgatgaa aaatttgtac agattgcgaa aaaaatggca aatttaattc ctaatagtaa
    32521 atgtaaatta atttctgcta caggtcatac aattcatgtg gaagatagtg atgaatttga
    32581 tacaatgata ttaggatttt taaaggagga gcaaaatgac taacagacaa tgggaaacac
    32641 ttagagaata tgatgaaatc aaatatgaat tttacgaagg gattgctaag gtaacaataa
    32701 atcgccctga agtacgcaat gcgtttacac ctaaaacagt tgctgaaatg attgacgcat
    32761 tttcacgtgc acgtgatgat caaaacgttt cagttatcgt attaactggt gaaggtgatt
    32821 tagcattctg ttctggtggt gaccagaaga aacgtggaca tggtggttat gtaggtgaag
    32881 accaaatccc tcgcttaaat gtattagatt tacagcgttt aattcgtatt attccaaaac
    32941 cggttatcgc gatggtaaaa ggttatgctg taggtggcgg taatgtacta aatgttgttt
    33001 gtgacttaac gattgctgct gataatgcta tttttggaca aactggtcct aaagtaggtt
    33061 catttgatgc aggttatggt tcaggatatt tagcacgtat cgttggacat aagaaagcac
    33121 gtgaaatctg gtacttatgt cgtcaataca atgcacaaga agctttagat atgggcctag
    33181 taaatacagt ggtaccttta gataaagttg aagatgaaac tgtgcaatgg tgtaaagaga
    33241 ttatgaaaca ctcaccaaca gctttacgat tccttaaagc agctatgaat gctgacacag
    33301 atggtttagc tggtttacaa caaatggctg gggatgcaac attgctttat tacacaactg
    33361 atgaagcgaa agaaggccgt gatgcgttta aagaaaaacg tgatcctgac ttcgatcaat
    33421 tccctaaatt cccataagtt attttgaata tgatattaag tcacttgcgt cgtttattag
    33481 cgacgatagg tggctttttt attttataag aatttaaaag agaattttaa ttaattatca
    33541 taaagataag atggtttgag taaattaata gagaaagaat aaatgttaaa gattattatt
    33601 acaatgaaaa aacgagctgg tgagaaattg aattctcgcc aacccgcttt atgaagtgaa
    33661 atcatttaaa ttagttatac taagcgctca taaacgattg ggcgcgaagt gccaatacct
    33721 tgtttggatg acgtttgcat gaggatatgc tgtgtatcat cataatcaag aatataagtg
    33781 atttcttcat tatcaataga tgaaaattta atgcgttgat gtgccgtatc tataaaaaga
    33841 atatgatatt gattgtgact tgtatcatcg ccatgacgta tacaaattga tttttgtaat
    33901 tgatgattac tccaattacc aatgaataaa ttgatattgg tttgttctag atgtgtgagt
    33961 ttggttgtgt cgtaaactaa atttataaat tgtagttgat acatagtttt acctgccttt
    34021 aatcaatatc tatattactt tttagtaacc tatcattgaa ccataccagt tataatcacg
    34081 attgaatgat aaatgtaata ggcttgaatc tgcatcttgg attgataatt ctgtatccca
    34141 aggattccag taaataagtt tttcttggtc attaatttta gcattaccaa caactgctag
    34201 ggcatgtcct aaatgtggat cattagggtt ttgagataca ctttgtgcaa gaatcataat
    34261 tcctacatta tcttttgtaa gttgatcaac ttgttcatat gatggtacgc cttcttgata
    34321 atgaatatct ctgccttgtg atttaccgta ttcaatcatt tgattaggga atgttgagca
    34381 attaggaagg tcttgctcac ttacttcagg gtataatgta cgcataatat catgtgcatt
    34441 ataagtgtct gtatttttag ttgcatttaa taatgctgcc atactaaatc ctgcacacca
    34501 tgagttatcg aattgttgtt ctctaatttt gaagtttttt aatgtatttt catattgaac
    34561 ttgatcttct tgtatcgctt cgttttcttc aactttagta ggtgttactg tattttttaa
    34621 ctcttgtttc aattttgctg aaactgtttt agcactttct ttttctttta cattaccagg
    34681 tagtggcgta gcttttacta atctaacttt gccatcttct tcaaaataaa accctttttc
    34741 atcagtaaga acagtgatat ttgaattttt atctttaatt tggtctaaat ctttagcgat
    34801 gaagtttgaa attttaacac tgtaattcat gtcttctttt gatttgttta aatcatcttt
    34861 atttttaggg ctaagtgtta aagtataaac aattttaccg tcttttataa ctggataata
    34921 gtaactatta tcttcttcac cattaaattt ataaatttta aaagcttcgc caagttcata
    34981 tttaccagtt tttgcattac tttgtttatc taatgcttta gcataaccag caaattgttg
    35041 ttgtgctaga tcttttactt tttgaggtac tttgtcactc ttaacattaa tttctagctg
    35101 tttagagtgt gaatcggctt tggctttatt gttattagca aatgcgccta gtgataaaat
    35161 aagcattgaa accattatga tgcttataat attgaatact ctagatttat atgaactatt
    35221 catataatac cctccattta aatcaaaata ttttgcgttg ctaagacttt gcttctattt
    35281 actaaatcta aattaagatg aagtttatgc agcgtcaggg ttgtctgaat tattgttatc
    35341 gccattgtct ggattatcag ggttgttagg gttgtcaggg ttatttggtt catctgggtt
    35401 gttagggtta tcaggattgt tagggttatc aggattgtta gggttatcag gattgttagg
    35461 gttatcagga ttatctgggt tattaggttg gtcatcgttg gcaaaatgga tatcttcaat
    35521 attttgtttt aagaagttgc gtacattttc attaataaat accgcaccat taaattcatt
    35581 tggtacaccg ccccaatgaa ttccgatcac ttcatttttt tcattaaata caggtgaacc
    35641 tgagttacca ccagttgtac ttaaatcata ttgcatagct tcgcctttga ggtaagtgat
    35701 ttttccttta ctttcccaca ttgttgctac aggtttatca ccaggatatc ctgttacagt
    35761 aatattttgg ttaacttgtg tttcagcatt attactcatt gttgctggtt taactacttc
    35821 accaatatgt ttgttttgct cattagggga gaatttaact attgctaaat caccttcgcc
    35881 tgaatattta gtgatttgtt cagcagtgaa accaccattt ggataattgt cttggttaat
    35941 tgcagaaggg aatgctttta aagcatgagg atcaccgtgc gtagcatcta cgacgtgttt
    36001 atttgttaaa agagtatctt tacctacaac tacaccggaa gcaataaatg taccagtagg
    36061 tgcttcaact tgaatataag ttacgggtgc ataatgacca ttcgttgtat ctgtgatttg
    36121 gtgacgatcg ttattcggta atataacatt tgcgtgttca cgttgttcta atggtttaag
    36181 gttaccgcct tttttaatct taggtgtttg ctgtttgctt gactgcgttt gttgtggatg
    36241 attgtccata gcttttgatg ataacgcgtt tgctgctgga gaactcacaa gtgtcgctgt
    36301 tgtcaaagtt gcaacgaata aagaactaac ttttaaaaat ttacctttca tctaaaaacc
    36361 tccaaaaaat ttatttacaa gttaaatata acactaaaaa tttttaagtc aataagaata
    36421 tataaataaa ttaaaaagtt tttgtaaaga ttagagttta caaaaacatt aaggtaatta
    36481 aaattgaatt gtattatact ttattcaatt gagttaaatt gataagatcg tcaattgttt
    36541 gcatttatct aaaagaataa ataagaaagg aattgagagc gaatggaaag tatttgttta
    36601 taataataaa tagtaacttt tgaataataa ttgtttggcc aaaggtagat taatatgaat
    36661 ggtgatatat tatttgagtg cttaagtttc gaagaacaat tataagttag catattaaaa
    36721 ccttttgata gaatcatttt gagtgaggtg tttaaaggag aggaatataa ctcggtagta
    36781 tttacagtct ctatagagta ttatttaaaa cttatagaat ataaaaaact gaacgtacta
    36841 tgaatttagt tcacgacgtc cagttcaaca tatcattttt atttagtatt taaatattta
    36901 gcaagtctct tcataccttc ttttaaaaca tccatttcat aagcatagga aatccttaca
    36961 aatcctttac cgaattctgt aaaggatgag cctggaacga ttgctaaatg tgttgattca
    37021 agtaaatcga cacaaaattc gaaatcgtca tcggtgatat gtttaatact tgggaaaata
    37081 taaaacgcgc cttcaggttg agcggtaatc tcaaaaccta atttagttaa ttcagatact
    37141 aaataatttc ttcgttctac ataagcttcg ttcatatatt taggagcttc taatccttcg
    37201 ttaagtgctg ttatacatgc tatttgagct ggaacattgg cacaaataca attataggcg
    37261 tgcataaatg ttaatttatc aatcaaatat tgaggcccta atagaaaacc aattcttatt
    37321 ccggttgctg agtgtgattt acttaaacca ccaattaata ttaattgatc acgaatgtct
    37381 tcaaattcag cgaaggatac atgtttacca ctaaatgtat tttcagcata aatctcatcg
    37441 ctaataataa atatcggata tttttttaat acatttacga tatttaaaac ttcatttctt
    37501 tttaaaacta cgccagttgg attagtcgga taatttaaca agacagcttt tgtctttgga
    37561 gaaatatgac tttctaatgc atcaggtgta attttgaatt gtgttgctgt tgtatcaata
    37621 taaattggtt taccacctag tacttcgatg agtggtatgt agcctgcata aattggtccc
    37681 ggtattataa tttcatctcc aggctctatg atagaacgta acgttgtgtc tattgcttca
    37741 cttgctccat ttgtcacaat aatttcttca ggatcatagg aaaaatgata acgatttttg
    37801 aagtattgac taattgcttc gcgagtttct aataaccctt tattgtgaga gtatgatgtc
    37861 ttgtcattgt taatagcatc aatatatgcc tttttcacaa catcaggcat cgggaagtct
    37921 ggttggccaa tagttaaatt aacacaatca tccaaattat tcatacgatt tgaaaattgg
    37981 cgaatacttg gtgctcttaa atatttagaa ttagaattta aagaaagttt catttgtgac
    38041 acctcaaata taaatcaaat attgtctaaa aatttagaaa ttaataatat cataacatac
    38101 ttttaaacca aaaaagggta aattacttaa gctttatttg aaaaacgaaa aat
//
LOCUS       DAPDIM010000023        38079 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000023 DAPDIM010000000
VERSION     DAPDIM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 38079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38079
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.023"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            103..999
                     /gene="xerC"
                     /locus_tag="RFE25_001224"
     CDS             103..999
                     /gene="xerC"
                     /locus_tag="RFE25_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDU2816295.1"
                     /translation="MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQL
                     KTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKK
                     EKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFY
                     ANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLILNMKGEAITERGV
                     RYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHV
                     SNQQLRKVYLNAHPRAKKENET"
     gene            996..1541
                     /gene="hslV"
                     /locus_tag="RFE25_001225"
     CDS             996..1541
                     /gene="hslV"
                     /locus_tag="RFE25_001225"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HDU2816296.1"
                     /translation="MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVR
                     RLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEA
                     MLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYE
                     SLKVAADICVFTNDNIVVETL"
     gene            1607..3010
                     /gene="hslU"
                     /locus_tag="RFE25_001226"
     CDS             1607..3010
                     /gene="hslU"
                     /locus_tag="RFE25_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HDU2816297.1"
                     /translation="MDTAGIRLTPKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLL
                     DEESKQEISPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVES
                     MVRDLVDVSVRLVKAQKKSLVQDEATAKANEKLVKLLVPSMKKKASQTNNPLESLFGG
                     AIPNFGQNNEDEEEPPTEEIKTKRSEIKRQLEEGKLEKEKVRIKVEQDPGALGMLGTN
                     QNQQMQEMMNQLMPKKKVEREVAVETARKILADSYADELIDQESANQEALELAEQMGI
                     IFIDEIDKVATNNHNSGQDVSRQGVQRDILPILEGSVIQTKYGTVNTEHMLFIGAGAF
                     HVSKPSDLIPELQGRFPIRVELDSLSVEDFVRILTEPKLSLIKQYEALLQTEEVTVNF
                     TDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVD
                     DKLKSISTNKDLSAFIL"
     gene            3035..3808
                     /gene="codY"
                     /locus_tag="RFE25_001227"
     CDS             3035..3808
                     /gene="codY"
                     /locus_tag="RFE25_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDU2816298.1"
                     /translation="MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSR
                     RGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPEN
                     RELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
                     EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIV
                     NALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK"
     gene            3882..3956
                     /locus_tag="RFE25_001228"
     CDS             3882..3956
                     /locus_tag="RFE25_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816299.1"
                     /translation="MTLMIMLKSFLYFCLIFNQIDISH"
     gene            4155..4922
                     /gene="rpsB"
                     /locus_tag="RFE25_001229"
     CDS             4155..4922
                     /gene="rpsB"
                     /locus_tag="RFE25_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDU2816300.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKKVDEAYNFLKQVSEDGGQVLFVGTKKQAQESVKSEAERAGQFYINQRWLGGLLT
                     NYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGGIRDMKSMPQA
                     LFVVDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMA
                     DAILEGQQGVSNEEVAAEQNIDLDEKEKSEETEATEE"
     gene            4956..5069
                     /locus_tag="RFE25_001230"
     CDS             4956..5069
                     /locus_tag="RFE25_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816301.1"
                     /translation="MGDKILMLITFFKKKIEANYKYSIRVLAILPIIMLKS"
     gene            5104..5985
                     /locus_tag="RFE25_001231"
     CDS             5104..5985
                     /locus_tag="RFE25_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDU2816302.1"
                     /translation="MATISAKLVKELRKKTGAGMMDCKKALTETDGDIDKAIDYLREK
                     GIAKAAKKADRIAAEGLVHVETKGNDAVIVEINSETDFVARNEGFQELVKEIANQVLD
                     TKAETVEALMETTLPNGKSVDERIKEAISTIGEKLSVRRFAIRTKTDNDAFGAYLHMG
                     GRIGVLTVVEGSTDEEAARDVAMHIAAINPKYVSSEQVSEEEINHEREVLKQQALNEG
                     KPENIVEKMVEGRLRKYLQEICAVDQDFVKNPDVTVEAFLKTKGGKLVDFVRYEVGEG
                     MEKREENFADEVKGQMK"
     gene            6122..6844
                     /locus_tag="RFE25_001232"
     CDS             6122..6844
                     /locus_tag="RFE25_001232"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDU2816303.1"
                     /translation="MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAK
                     MDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRV
                     LTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVIL
                     MGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFS
                     IMEEGNIKRAVMGEKIGTLITK"
     gene            6863..7417
                     /gene="frr"
                     /locus_tag="RFE25_001233"
     CDS             6863..7417
                     /gene="frr"
                     /locus_tag="RFE25_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDU2816304.1"
                     /translation="MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYY
                     GAPTPVQQLASINVPEARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVP
                     ALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQ
                     KATDNSIKEIDQMIADKEKDIMSV"
     gene            7790..8560
                     /locus_tag="RFE25_001234"
     CDS             7790..8560
                     /locus_tag="RFE25_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDU2816305.1"
                     /translation="MFKKLINKKNTINNYNEELDSSNIPEHIAIIMDGNGRWAKKRKM
                     PRIKGHYEGMQTIKKITRIASDIGVKYLTLYAFSTENWSRPESEVNYIMNLPVNFLKT
                     FLPELIEKNVKVETIGFTDKLPKSTIEAINNAKEKTANNTGLKLIFAINYGGRAELVH
                     SIKNMFDELHQQGLNSDIIDETYINNHLMTKDYPDPELLIRTSGEQRISNFLIWQVSY
                     SEFIFNQKLWPDFDEDELIKCIKIYQSRQRRFGGLSEE"
     gene            8567..9349
                     /locus_tag="RFE25_001235"
     CDS             8567..9349
                     /locus_tag="RFE25_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDU2816306.1"
                     /translation="MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNM
                     NMIKFVSVPGLISAVGLIIIMLPQHAGPWVQVIQLKSLIAMSFIVLSYTVLSKNRFSF
                     MDAAFCLMSVAYVGIGFMFFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLW
                     PVISPNKTIEGFIGGLFCSLIVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVES
                     GFKRHFGVKDSGRILPGHGGILDRFDSFMFVLPLLNILLIQS"
     gene            9561..10847
                     /gene="rseP"
                     /locus_tag="RFE25_001236"
     CDS             9561..10847
                     /gene="rseP"
                     /locus_tag="RFE25_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDU2816307.1"
                     /translation="MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMG
                     PKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILD
                     DHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRD
                     RQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGL
                     QKGDKIVQIGKYKISEFDDVDKALDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTK
                     VSSETKYVLGFQPASEHTLFKPIVYGFESFLKGSTLIFTAVVGMLASIFTGGFSFDML
                     NGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFR
                     KPVNKKAETTIIAIGAIFMVVIMILVTWNDIRRYFL"
     gene            10867..12570
                     /locus_tag="RFE25_001237"
     CDS             10867..12570
                     /locus_tag="RFE25_001237"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDU2816308.1"
                     /translation="MKQSKVFIPTMRDVPSEAEAQSHRLLLKSGLIKQSTSGIYSYLP
                     LATRVLNNITAIVRQEMERIDSVEILMPALQQAELWEESGRWGAYGPELMRLQDRHGR
                     QFALGPTHEELVTSIVRNELKSYKQLPMTLFQIQSKFRDEKRPRFGLLRGREFIMKDA
                     YSFHADEASLDQTYQDMYQAYSRIFERVGINARPVVADSGAIGGSHTHEFMALSAIGE
                     DTIVYSKESDYAANIEKAEVVYEPNHKHSTVQPLEKIETPNVKTAQELADFLGRPVDE
                     IVKTMIFKVDGEYIMVLVRGHHEINDIKLKSYFGTDNIELATQDEIVNLVGANPGSLG
                     PVIDKEIKIYADNFVQDLNNLVVGANEDGYHLINVNVGRDFNVDEYGDFRFILEGEKL
                     SDGSGVAHFAEGIEVGQVFKLGTKYSESMNATFLDNQGKAQPLIMGCYGIGISRTLSA
                     IVEQNHDDNGIVWPKSVTPFDLHLISINPKKDDQRELADALYAEFNTKFDVLYDDRQE
                     RAGVKFNDADLIGLPLRIVVGKRASEGIVEVKERLTGDSEEVHIDDLMTVITNKYDNL
                     K"
     gene            12834..17144
                     /locus_tag="RFE25_001238"
     CDS             12834..17144
                     /locus_tag="RFE25_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDU2816309.1"
                     /translation="MTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEF
                     HITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTA
                     LSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIF
                     ETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGK
                     PIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFT
                     RKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRV
                     EFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMI
                     YGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEI
                     IDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASF
                     DMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAI
                     YDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKN
                     LFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIA
                     KYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFE
                     HDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELA
                     DRIERVVPIKDELYTPRMEGANEEIRELSYTNARKLYGEDLPQIVIDRLEKELKSIIG
                     NGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKT
                     SEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEY
                     QPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGC
                     TGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLD
                     ILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVP
                     EFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRD
                     DIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFP
                     KAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYS
                     RYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPG
                     LGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM
                     "
     gene            17434..17901
                     /gene="rimP"
                     /locus_tag="RFE25_001239"
     CDS             17434..17901
                     /gene="rimP"
                     /locus_tag="RFE25_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDU2816310.1"
                     /translation="MSKITEQVEVIVQPIMEDLNFELVDVEYVKEGRDHFLRISIDKE
                     GGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFV
                     SLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI"
     gene            17922..19097
                     /gene="nusA"
                     /locus_tag="RFE25_001240"
     CDS             17922..19097
                     /gene="nusA"
                     /locus_tag="RFE25_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDU2816311.1"
                     /translation="MSSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSAR
                     NVRVELNMDQGTFKVIARKDVVEEVFDDRDEVDLSTALVKNPAYEIGDIYEEDVTPKD
                     FGRVGAQAAKQAVMQRLRDAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEA
                     VLSEAERSPNEKYIPNERIKVYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYD
                     GTVIVKSVAREAGDRSKISVFSENNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQW
                     NEDPKVFVKNALSPSQVLEVIVDETNQSTVVVVPDYQLSLAIGKRGQNARLAAKLTGW
                     KIDIKSETDAREAGIYPVVEAEKVTEEDIALEDADTTESTEEVNDVSVETNVEKESE"
     gene            19118..19402
                     /locus_tag="RFE25_001241"
     CDS             19118..19402
                     /locus_tag="RFE25_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDU2816312.1"
                     /translation="MKKKKIPMRKCILSNEMHPKKDMIRVVVNKEGEIFADVTGKKQG
                     RGAYVSKDVAMVEKAQQKEILEKYFKASKEQLDPVYKEIIRLIYREEIPK"
     gene            19399..19716
                     /locus_tag="RFE25_001242"
     CDS             19399..19716
                     /locus_tag="RFE25_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ family RNA-binding protein"
                     /protein_id="HDU2816313.1"
                     /translation="MSIDQILNFLGLAMRAGKVKTGESVIVNEIKKGNLKLVIVANDA
                     SDNTAKLITDKCKSYKVPFRKFGNRNELGIALGKGERVNVGITDPGFAKKLLSMIDEY
                     HKE"
     gene            19721..21838
                     /gene="infB"
                     /locus_tag="RFE25_001243"
     CDS             19721..21838
                     /gene="infB"
                     /locus_tag="RFE25_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDU2816314.1"
                     /translation="MSKQRIYEYAKELNLKSKEIIDELKSMNIEVSNHMQALEDDQIK
                     ALDKKFKKEQKNDNKQSTQNNHQKSNNQNQNKGQQKDNKKNQQQNNKGNKGNKKNNRN
                     NKKNNKNNKPQNQPAAPKEIPSKVTYQEGITVGEFADKLNVESSEIIKKLFLLGIVAN
                     INQSLNQETIELIADDYGVEVEEEVVINEEDLSIYFEDEKDDPEAIERPAVVTIMGHV
                     DHGKTTLLDSIRHTKVTAGEAGGITQHIGAYQIENDGKKITFLDTPGHAAFTTMRARG
                     AQVTDITILVVAADDGVMPQTIEAINHAKEAEVPIIVAVNKIDKPTSNPDRVMQELTE
                     YGLIPEDWGGETIFVPLSALSGDGIDDLLEMIGLVAEVQELKANPKNRAVGTVIEAEL
                     DKSRGPSASLLVQNGTLNVGDAIVVGNTYGRIRAMVNDLGQRIKTAGPSTPVEITGIN
                     DVPQAGDRFVVFSDEKQARRIGESRHEASIVQQRQESKNVSLDNLFEQMKQGEMKDLN
                     VIIKGDVQGSVEALAASLMKIDVEGVNVRIIHTAVGAINESDVTLANASNGIIIGFNV
                     RPDSGAKRAAEAENVDMRLHRVIYNVIEEIESAMKGLLDPEFEEQVIGQAEVRQTFKV
                     SKVGTIAGCYVTEGKITRNAGVRIIRDGIVQYEGELDTLKRFKDDAKEVAKGYECGIT
                     IENYNDLKEGDVIEAFEMVEIKR"
     gene            22224..22574
                     /gene="rbfA"
                     /locus_tag="RFE25_001244"
     CDS             22224..22574
                     /gene="rbfA"
                     /locus_tag="RFE25_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDU2816315.1"
                     /translation="MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDL
                     SQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGN
                     KIERMIQDLHKQDR"
     gene            22743..23660
                     /gene="truB"
                     /locus_tag="RFE25_001245"
     CDS             22743..23660
                     /gene="truB"
                     /locus_tag="RFE25_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDU2816316.1"
                     /translation="MYNGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAG
                     VLPVCIGNATRVSDYVMDMGKAYEATVSIGRSTTTEDQTGDTLETKGVHSADFNKDDI
                     DRLLENFKGVIEQIPPMYSSVKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDF
                     KENECHFKIRVICGKGTYIRTLATDIGVKLGFPAHMSKLTRIESGGFVLKDSLTLEQI
                     KELHEQDSLQNKLFPLEYGLKGLPSIKIKDSHIKKRILNGQKFNKNEFDNKIKDQIVF
                     IDDDSEKVLAIYMVHPTKESEIKPKKVFN"
     gene            23675..24646
                     /gene="ribF"
                     /locus_tag="RFE25_001246"
     CDS             23675..24646
                     /gene="ribF"
                     /locus_tag="RFE25_001246"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HDU2816317.1"
                     /translation="MKVIEVTHPIQSKQYITEDVAMAFGFFDGMHKGHDKVFDILNEI
                     AEARSLKKAVMTFDPHPSVVLNPKRKRTTYLTPLSDKIEKISQHDIDYCIVVNFSSRF
                     ANVSVEDFVENYIIKNNVKEVIAGFDFTFGKFGKGNMTVLQEYDAFNTTIVSKQEIEN
                     EKISTTSIRQDLINGELQKANDALGYIYSIKGTVVQGEKRGRTIGFPTANIQPSDDYL
                     LPRKGVYAVSIEIGTENKLYRGVANIGVKPTFHDPNKAEVVIEVNIFDFEDNIYGERV
                     TVNWHHFLRPEIKFDGIDPLVKQMNDDKSRAKYLLAVDFGDEVAYNI"
     gene            24761..25030
                     /gene="rpsO"
                     /locus_tag="RFE25_001247"
     CDS             24761..25030
                     /gene="rpsO"
                     /locus_tag="RFE25_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDU2816318.1"
                     /translation="MAISQERKNEIIKEYRVHETDTGSPEVQIAVLTAEINAVNEHLR
                     THKKDHHSRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIRR"
     gene            25399..27495
                     /gene="pnp"
                     /locus_tag="RFE25_001248"
     CDS             25399..27495
                     /gene="pnp"
                     /locus_tag="RFE25_001248"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDU2816319.1"
                     /translation="MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLST
                     ATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPL
                     FPKGYKHDVQIMNMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGK
                     YIINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVDF
                     QQQIVDHIQPVKQEFIPAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKE
                     EIVNEFIDEEDPENELLIKEVYAILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSE
                     VGILPRTHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVG
                     ETGPVRAPGRREIGHGALGERALKYIIPDTADFPYTIRIVSEVLESNGSSSQASICGS
                     TLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITA
                     IQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTELSAYAPKVVTMTIKP
                     DKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAREIIEEITREAE
                     VGQTYQATVKRIEKYGAFVGLFPGKDALLHISQISKNRIEKVEDVLKIGDTIEVKITE
                     IDKQGRVNASHRALEE"
     gene            27731..29404
                     /locus_tag="RFE25_001249"
     CDS             27731..29404
                     /locus_tag="RFE25_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDU2816320.1"
                     /translation="MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMF
                     PEDEMLGIDIVIPDISYVLENKDKLKGIFLTHGHEHAIGAVSYVLEQLDAPVYGSKLT
                     IALIKENMKARNIDKKVRYYTVNNDSIMRFKNVNISFFNTTHSIPDSLGVCIHTSYGA
                     IVYTGEFKFDQSLHGHYAPDIKRMAEIGEEGVFVLISDSTEAEKPGYNTPENVIEHHM
                     YDAFAKVRGRLIVSCYASNFIRIQQVLNIASKLNRKVSFLGRSLESSFNIARKMGYFD
                     IPKDLLIPITEVDNYPKNEVIIIATGMQGEPVEALSQMAQHKHKIMNIEEGDSVFLAI
                     TASANMEVIIANTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMINIMKPEYFIPVQ
                     GEFKMQIAHAKLAAEAGVAPEKIFLVEKGDVINYNGKDMILNEKVNSGNILIDGIGIG
                     DVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEDLLREAEE
                     KVREIVEAGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI"
     gene            29661..32027
                     /locus_tag="RFE25_001250"
     CDS             29661..32027
                     /locus_tag="RFE25_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDU2816321.1"
                     /translation="MAQAKKKSTAKKKTASKKRTNSRKKKNDNPIRYVIAILVVVLMV
                     LGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLATGFITYSKRIPKTRRTAGSIVLQ
                     IALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLIS
                     LFGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKRE
                     EKARLKEEQKARQNEQPQIKDVSDFTEVPQERDIPIYGHTENESKSQCQPSRKKRVFD
                     AENSSNNIVNHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSYVVPPLTLLNQPAKQ
                     KATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHN
                     DIALALAAKDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRD
                     ISGDPITVPLNEMPHLLVAGSTGSGKSVCINGIITSILLNAKPHEVKLMLIDPKMVEL
                     NVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNELIRKQNQ
                     ELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVD
                     VITGIIKNNIPSRIAFAVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGA
                     FLSDQEVQDVVNYVVEQQQANYVKEIEPDAPVDKSEMKSEDALYDEAYLFVVEQQKAS
                     TSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV"
     gene            32032..32745
                     /locus_tag="RFE25_001251"
     CDS             32032..32745
                     /locus_tag="RFE25_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDU2816322.1"
                     /translation="MSEMNAVYNVKQYILNLIKQNKLEYGDQLPSNLSIARELNVKTD
                     DVYEAIQALITEQVIKDNFEEGTSVKSLPPFFYPLNELISIGQMIKNAGFECGTEYLN
                     FDEQPATMLDANLLSVEEGYPVTIIERLRTADGEPVVYCLDKIAKKELTCTEYQMSNG
                     SILSAIKEQSNHNICYADTEIEAVNYEPRISEVLNASPHEGLILLKITHYNELDEPIL
                     YSLNYMKNSLVQFKITRKI"
     gene            32776..34041
                     /locus_tag="RFE25_001252"
     CDS             32776..34041
                     /locus_tag="RFE25_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDU2816323.1"
                     /translation="MSRQSQPNIHIKVSPTTKFKTTTIVFKFMAPLEYDTITARSLLS
                     KLLVRATKKWPTDKSFNNHLADLYGAYVNSTISKFKDQHVITFSLEIVNERYLRNGES
                     LFNQGLDLLQEIIWNPLIENKAFNDNFVNQEKTLLAKKIEAMVDNKAQYSFLKLLDHM
                     FENEAYKYLSTGQLEQIPHITAETLYHTYQSMINNDQCSVYVVGNVEPESVEKQIREK
                     FALKPFDKHQFQHSTHHLHDEEVDYIVEYDDVDQAKLNMGYRFPTQYGQSGYAAFVVF
                     NMMFGGDPSSVLFNEVREKQSLAYSIHSQIDGKNGYLFVLSGVSSDKYETAKDTIISE
                     FEKIKAGDFTEEKLELAKKVIISHRYESEDRPKSIIEIMHNQILLEQPQSKETFINDI
                     QKVSREDIVSVAEKAFLDTIYVLTKGGDK"
     gene            34041..35327
                     /locus_tag="RFE25_001253"
     CDS             34041..35327
                     /locus_tag="RFE25_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDU2816324.1"
                     /translation="MKERYYELIDERVFEQELENGLRLFIIPKPGFQKTFVTYTTQFG
                     SLDNQFKPLGQDQFVTVPDGVAHFLEHKLFEKEEEDLFTAFAEDNAQANAFTSFDRTS
                     YLFSATDNIENNIKRLLTMVETPYFTKETVDKEKGIIAEEIKMYQEQPGYKLMFNTLR
                     AMYQRHPIRVDIAGSVESIYDITKDDLYLCYETFYHPSNMVLFVVGDVNPEEICRIVK
                     QHEDARNKVNQPKIERGLVDEPEDVKEAFVTESMKIQSPRLMLGFKNKPLQEAPQKYV
                     QRDLEMSLFFELIFGEETDFYQNLLNEGLIDDTFGYQFVLEPTYSFSIVTSATEEPDK
                     LKKLLLDELRDKKGNFQDAEAFELLKKQFIGEFISSLNSPEYIANQYTKLYFEGVSVF
                     DMLDIVENITLDSINETSSLYLNLDQQVDSRLEIKK"
     gene            35327..36031
                     /locus_tag="RFE25_001254"
     CDS             35327..36031
                     /locus_tag="RFE25_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDU2816325.1"
                     /translation="MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFN
                     DDKVRFIQADLSQTIDIDKTFGDIKSLDCLIYASGQSLYGVLQDMKDHDIDACYQLNV
                     LQLIRLCRYFVDVLRQSANGRIIVISSIWGETGASMETIYSAMKSAQLGFVKALSQEL
                     ALTSVTVNAIAPGFVAGNMASEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHSNA
                     RSVTGTIQKVNGAWYI"
     gene            36136..36963
                     /locus_tag="RFE25_001255"
     CDS             36136..36963
                     /locus_tag="RFE25_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfK family protein"
                     /protein_id="HDU2816326.1"
                     /translation="MTVAEKKEWYLEYEIEINRPGLLGDVSSLLGMLGISIVTINGVD
                     QGKRGLLIKTDNLEKVERFEQIARGINEIEITKLKKPELRDRLAVRHGRYIEQDAKDK
                     KTFRFEREDLGLLVDFLAELFKEEGHKLIGIRGMPRVGKTESIVAGSVCAHKRWLFIS
                     STLIKQTVRSSLIKGEYDANHVYIIDGAVTARESNPKHQELVNEVMTLPSIKVVEHPD
                     LFVETSTCTMEDFDYIIELRENENQEIHYEEMKKQTVQSKNNLDFGDPFGGGFGFFE"
     gene            36982..37374
                     /locus_tag="RFE25_001256"
     CDS             36982..37374
                     /locus_tag="RFE25_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2816327.1"
                     /translation="MKTVGEALKGRRERLGMTLTELEQRTGIKREMLVHIENNEFDQL
                     PNKNYSEGFIRKYASVVNIEPNQLIQAHQDEIPSNQAEWDEVITVFNNNKDLDYKSKS
                     KEPIQLLVIMGITVLITLLLWIMLVLIF"
     gene            37408..37986
                     /gene="pgsA"
                     /locus_tag="RFE25_001257"
     CDS             37408..37986
                     /gene="pgsA"
                     /locus_tag="RFE25_001257"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDU2816328.1"
                     /translation="MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELL
                     ISGFIFILASLSDFVDGYLARKWNLVTNMGKFLDPLADKLLVASALIVLVQLGLTNSV
                     VAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL
                     SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK"
BASE COUNT        13947 a         5160 c         7453 g        11519 t
ORIGIN      
        1 gttacaatta tttaattctc aaaagattta gaattgatta tcaaattact gtaagccctt
       61 tgctgtatat gctacaattc ttattgatgg agggtaaatg tattgaatca tattcaagaa
      121 gcgtttttaa atacattgaa agttgaacgg aatttttcgg aacatacatt gaaatcatat
      181 caagatgact taattcagtt taatcaattt ttagaacaag aacatttaca gttgaaaact
      241 tttgaataca gagatgctag aaattatttg agctatttat attcaaatca tttgaaaaga
      301 acatctgttt ctcgtaaaat ctcaacgtta agaactttct atgaatattg gatgacgctt
      361 gatgagaaca ttattaatcc atttgttcaa ttagtacatc cgaaaaaaga aaaatatctt
      421 ccgcaattct tttacgaaga agaaatggaa gcgttattca aaactgtaga agaggacact
      481 tcaaaaaatt tacgggatcg agttattctt gaattgttgt atgctacagg catccgtgtt
      541 tcggaattag taaatattaa aaaacaagat atagattttt acgcgaatgg tgttaccgta
      601 ttaggaaaag ggagcaaaga gcgttttgta ccgtttggtg cttattgtag acaaagcatc
      661 gaaaattatt tagaacattt caaaccaatt cagtcatgca atcatgattt tcttatttta
      721 aatatgaagg gtgaagcaat cactgaacgc ggtgtacgat atgttttaaa tgatattgtt
      781 aaacgaacag caggcgtaag tgagattcat ccccacaagc tcagacatac atttgcaacg
      841 catttattga atcaaggtgc agacctaaga acagtacaat cgttattagg tcatgttaat
      901 ttgtcaacaa ctggtaaata tacacacgta tctaaccaac aattaagaaa agtgtatcta
      961 aatgcacatc ctcgagcgaa aaaggagaat gaaacatgag taatacaaca ttacatgcaa
     1021 caacaattta tgctgtaaga cataatggga aagcagctat ggctggagat ggacaagtaa
     1081 cgcttggtca acaagtcatc atgaaacaaa cggcaagaaa agtgcgacgt ttatatgaag
     1141 gtaaagtgtt agctggtttc gcaggtagtg tagcagatgc gtttacgtta tttgaaaaat
     1201 ttgaaacaaa attacaacag tttagtggta acttagaaag agctgctgtt gaattggcac
     1261 aagaatggcg aggcgataaa caattacgtc aattagaagc tatgctaatt gtaatggata
     1321 aagatgctat tttagttgtc agtggaactg gcgaagttat tgccccagat gatgacctta
     1381 tcgctattgg atcagggggc aactacgcat taagcgcagg acgtgcattg aaacgccatg
     1441 catcgcattt gtctgctgaa gaaatggcat atgagagctt gaaagtagcg gctgatattt
     1501 gtgtctttac caacgataat attgttgttg aaacactata ataatcagag cacgataaat
     1561 aattacgacc aattaatttt agttaaaaga cggaggaatg aaattaatgg atacagctgg
     1621 aataagatta actccaaaag aaatcgtatc taaattaaat gaatatatcg ttggacaaaa
     1681 tgatgctaaa cgtaaagtgg caattgccct acgtaatcga tacagaagaa gtttattaga
     1741 tgaggaatca aagcaagaaa tttcacctaa aaatattttg atgattggac caaccggcgt
     1801 tggtaaaact gaaattgcaa gaagaatggc caaagttgtc ggcgcgccat ttataaaagt
     1861 agaagctact aaatttactg aggtaggtta tgtaggacga gatgttgaaa gtatggttag
     1921 agatcttgtt gatgtttcag taagattagt caaggcgcag aaaaaatcat tggtacaaga
     1981 tgaagcaaca gctaaggcca atgaaaaact tgttaagtta ttagttccaa gtatgaaaaa
     2041 gaaagcgtct caaacgaata atcctttaga gtcacttttc ggaggtgcaa ttccaaattt
     2101 cggacaaaat aacgaagatg aagaagaacc acctactgag gaaattaaaa caaaacgttc
     2161 tgaaattaag agacagctag aagaaggcaa acttgaaaaa gaaaaggtaa gaattaaagt
     2221 cgaacaagat cctggtgctt taggtatgct aggtacaaat caaaatcagc aaatgcaaga
     2281 gatgatgaat caattaatgc ctaaaaagaa agttgagcga gaagttgctg ttgagacggc
     2341 aaggaaaatc ttagctgata gttatgcgga tgaactaatt gatcaagaaa gcgctaacca
     2401 agaagcgctt gaattagcag aacaaatggg tatcatcttt atagatgaaa tcgacaaagt
     2461 tgcgacgaat aatcataata gtggtcaaga tgtctcaaga caaggtgttc aaagagatat
     2521 tttacctata cttgaaggta gcgttattca aaccaaatat ggtactgtga atactgaaca
     2581 tatgctgttt ataggtgctg gagctttcca tgtatctaag ccgagtgact tgataccaga
     2641 attgcaaggt cgttttccga ttagagttga acttgatagt ttatcggtag aagattttgt
     2701 aagaattttg acagaaccaa aattgtcatt aattaaacaa tatgaagcat tgcttcaaac
     2761 agaagaagtt actgtaaact ttaccgatga agcaattact cgcttagctg agattgctta
     2821 tcaagtaaat caagatacag acaacattgg tgcacgtcga cttcatacaa ttttagaaaa
     2881 gatgctagaa gatttatcat tcgaagcacc aagtatgccg aatgcagttg tagatattac
     2941 cccacaatat gttgatgata aattaaaatc aatttcaaca aataaagatt taagtgcatt
     3001 tattctataa aaatatacaa aaggagaaaa attcatgagc ttattatcta aaacgagaga
     3061 gttaaacacg ttacttcaaa aacacaaagg tattgcggtt gattttaaag atgtagcaca
     3121 aacgattagt agcgtaactg taacaaatgt atttattgta tcgcgtcgag gtaaaatttt
     3181 agggtcgagt ctaaatgaat tattaaaaag tcaaagaatt attcaaatgt tggaagaaag
     3241 acatattcca agtgaatata cagaacgatt aatggaagtt aaacaaacag aatcaaatat
     3301 tgatatcgac aatgtattaa cagtattccc acctgaaaac agagaattat tcatagatag
     3361 tcgtacaact atcttcccaa ttttaggtgg aggagaaaga ttaggtacat tagtacttgg
     3421 tcgagtacat gatgatttta atgaaaatga tttggtacta ggtgaatatg ctgctacagt
     3481 tattggtatg gaaatcttac gtgagaagca tagtgaagta gaaaaagaag cgcgcgataa
     3541 agctgctatt acaatggcaa ttaattcatt atcttattct gaaaaagaag cgattgaaca
     3601 tatctttgaa gaacttggcg gtacggaagg cctattaatc gcatcaaaag ttgcagatag
     3661 agttggtatt actagatctg taattgtaaa tgcactacgt aaattagaaa gtgctggtgt
     3721 aattgaatca cgttctttag gaatgaaagg tactttcatt aaagttaaaa aagaaaaatt
     3781 cttagatgaa ttagaaaaaa gtaaataagt cgatgagtct gggacataat tcaatgtcct
     3841 agtcgtgacg atgttatctt ggcagtagtc aactcaacga aatgactttg atgattatgt
     3901 tgaagtcatt tctttatttt tgtctaattt tcaatcaaat tgatatttca cattaacttg
     3961 atagaattac ctttaaattt atggaaaaat gcttgaaaaa catttgcttt agacacggca
     4021 ttatgttata tttattttcg gctataaagc caatacacac atatcaaacg tgattgtgta
     4081 aagggtgcaa tatttatata ttgtctttac aatagtttgc tatggaggta attaaccaat
     4141 aggaggaatt tataatggca gtaatttcaa tgaaacaatt actagaagcg ggtgttcact
     4201 tcggtcacca aacacgtcgt tggaacccaa aaatgaaaaa atatatcttc actgagagaa
     4261 atggtattta tatcatcgac ttacaaaaaa cagtgaaaaa agtagacgag gcatacaact
     4321 tcttgaaaca agtttcagaa gatggtggac aagtcttatt cgtaggaact aaaaaacaag
     4381 cacaagaatc agttaaatct gaagcagaac gtgctggtca attctacatt aaccaaagat
     4441 ggttaggtgg attattaact aactataaaa caatctcaaa acgaatcaaa cgtatttctg
     4501 aaattgaaaa aatggaagaa gatggtttat tcgaagtatt acctaaaaaa gaagtagtag
     4561 aacttaaaaa agaatacgac cgtttaatca aattcttagg cggaattcgt gatatgaaat
     4621 caatgcctca agcattattc gtagttgacc cacgtaaaga gcgtaatgca attgctgaag
     4681 ctcgtaaatt aaatattcct atcgtaggta tcgttgacac taactgtgat cctgacgaaa
     4741 ttgactacgt tatcccagca aacgacgatg ctatccgtgc ggttaaatta ttaactgcta
     4801 aaatggcaga tgcaatctta gaaggtcaac aaggcgtttc taatgaagaa gtagctgcag
     4861 aacaaaacat cgatttagat gaaaaagaaa aatcagaaga aacagaagca actgaagaat
     4921 aatcaactgt tgaatctgac ttagatatag tttaaatggg tgataagata ttaatgctta
     4981 tcaccttttt taaaaagaaa atcgaggcaa attacaaata ttcaattaga gtattggcaa
     5041 tcttgcctat aataatgcta aaatcataat atataaaatg ataacttatt ggaggaataa
     5101 tgaatggcaa ctatttcagc aaaacttgtt aaagaattac gtaaaaaaac tggcgcgggt
     5161 atgatggatt gtaaaaaagc gctaactgaa actgatggtg acatcgataa agcgattgat
     5221 tacctacgtg aaaaaggtat tgctaaagca gctaaaaaag cagaccgtat tgcggctgaa
     5281 ggtttagtac atgtagaaac taaaggtaac gacgcagtta tcgttgaaat caactctgaa
     5341 acagactttg ttgctcgtaa cgaaggattc caagagttag ttaaagaaat cgctaatcaa
     5401 gtattagata caaaagctga aactgttgaa gctttaatgg aaacaacttt accaaatggt
     5461 aaatcagttg atgaaagaat taaagaagca atttcaacaa tcggtgaaaa attaagtgtt
     5521 cgtcgttttg ctatcagaac taaaactgat aacgatgctt tcggcgctta cttacacatg
     5581 ggtggacgca ttggtgtatt aacagttgtt gaaggttcaa ctgacgaaga agcagcaaga
     5641 gacgttgcta tgcatatcgc tgcaatcaac cctaaatatg tttcttctga acaagttagc
     5701 gaagaagaaa tcaaccacga aagagaagtt ttaaaacaac aagcattaaa tgaaggtaaa
     5761 ccagaaaaca tcgttgaaaa aatggtggaa ggacgtttac gtaaatactt acaagaaatt
     5821 tgtgctgtag atcaagactt cgttaaaaac cctgatgtaa cagttgaagc tttcttaaaa
     5881 acaaaaggtg gaaaacttgt tgacttcgta cgctatgaag taggcgaagg tatggaaaaa
     5941 cgcgaagaaa actttgcgga tgaagttaaa ggacaaatga aataatctgt cataaagtaa
     6001 aacaaggaag aagacacctt taatgttgct ttattaaaat gtaaatcatt ctaataaaac
     6061 gacaactgtg tcttctttac ttgtatatgt tacatatatt cacgatagag aggataagaa
     6121 aatggctcaa atttctaaat ataaacgtgt agttttgaaa ctaagtggtg aagcgttagc
     6181 tggagaaaaa ggatttggca taaatccagt aattattaaa agtgttgctg agcaagtggc
     6241 tgaagttgct aaaatggact gtgaaatcgc agtaatcgtt ggtggcggaa acatttggag
     6301 aggtaaaaca ggtagtgact taggtatgga ccgtggaact gctgattaca tgggtatgct
     6361 tgcaactgta atgaatgcct tagcattaca agatagttta gaacaattgg attgtgatac
     6421 acgagtatta acatctattg aaatgaagca agtggctgaa ccttatattc gtcgtcgtgc
     6481 aattagacac ttagaaaaga aacgcgtagt tatttttgct gcaggtattg gaaacccata
     6541 cttctctaca gatactacag cggcattacg tgctgcagaa gttgaagcag atgttatttt
     6601 aatgggcaaa aataatgtag atggtgtata ttctgcagat cctaaagtaa acaaagatgc
     6661 ggtaaaatat gaacatttaa cgcatattca aatgcttcaa gaaggtttac aagtaatgga
     6721 ttcaacagca tcctcattct gtatggataa taacattccg ttaactgttt tctctattat
     6781 ggaagaaggg aatattaaac gtgctgttat gggtgaaaag ataggtacgt taattacaaa
     6841 ataaatttag aggtgtaaaa taatgagtga cattattaat gaaactaaat caagaatgca
     6901 aaaatcaatc gaaagcttat cacgtgaatt agctaatatc agtgcaggaa gagctaattc
     6961 aaatttatta aacggcgtaa cagttgatta ctatggtgca ccaacacctg tacaacaatt
     7021 agcaagcatc aatgttccag aagcacgttt acttgttatt tctccatacg acaaaacttc
     7081 tgtagctgac atcgaaaaag cgataatagc ggctaactta ggtgtcaacc caacaagtga
     7141 tggtgaagtg atacgtattg cagtacctgc cttaacagaa gagcgtagaa aagagcgcgt
     7201 taaagatgtt aagaaaattg gtgaagaagc taaagtatct gttcgaaata ttcgtcgtga
     7261 tatgaatgat cagttgaaaa aagatgaaaa aaatggcgac attactgaag atgagttgag
     7321 aagtggtact gaagatgttc agaaagcaac agacaattca ataaaagaaa ttgatcaaat
     7381 gattgctgat aaagaaaaag atattatgtc agtataaaac taatatacaa tgacatatta
     7441 aaatgccagt attaaacgat aatgtaacat ttaaaatggg catgtttaat taaatcaaag
     7501 atgcatgtga taatttaaat tcacaatgag cataaaaatg gtgtttaaac aagttaatta
     7561 aacatatact ttataaataa taggcattag gtatattgct ataataaagt tatgtaattt
     7621 ttaacctcag tatgtatgtc acatttctgg tgtaaactgt accgagtcag actttggtac
     7681 agttttttta tttgcttatt caatgcatta aatgagtatg ataaaatgat aatgattgtt
     7741 tagtaactta tattatatga cagagatgat caggctcgga ggaaagacca tgtttaaaaa
     7801 gctaataaat aaaaagaaca ctataaataa ttataatgaa gaattagact cgtctaatat
     7861 acctgaacat atcgctatta ttatggatgg taatgggcga tgggctaaga agcgaaaaat
     7921 gcctagaatt aaaggccatt acgaaggtat gcaaacaata aaaaaaatta ctaggatagc
     7981 tagtgatatt ggtgttaagt acttaacttt atatgccttt tccactgaaa attggtcaag
     8041 acctgaaagt gaagtaaatt atattatgaa tttgcctgtc aatttcttaa agacattctt
     8101 accggaacta attgaaaaaa atgtcaaagt tgaaacaatt ggatttactg ataagttgcc
     8161 aaaatcaacg atagaagcaa ttaataatgc taaagaaaag acagctaata ataccggctt
     8221 aaaattaata tttgcaatta attatggtgg cagagcagaa cttgttcata gtattaaaaa
     8281 tatgtttgac gagcttcatc aacaaggttt aaatagtgat atcatagatg aaacatatat
     8341 aaacaatcat ttaatgacaa aagactatcc tgatccagag ttgttaattc gtacttcagg
     8401 agaacaaaga ataagtaatt tcttgatttg gcaagtttcg tatagtgaat ttatctttaa
     8461 tcaaaaatta tggcctgact ttgacgaaga tgaattaatt aaatgtataa aaatttatca
     8521 gtcacgtcaa agacgctttg gcggattgag tgaggagtag tatagtatga aagttagaac
     8581 gctgacagct attattgcct taatcgtatt cttgcctatc ttgttaaaag gcggccttgt
     8641 gttaatgata tttgctaata tattagcatt gattgcatta aaagaattgt tgaatatgaa
     8701 tatgattaaa tttgtttcag ttcctggttt aattagtgca gttggtctta tcatcattat
     8761 gttgccacaa catgcagggc catgggtaca agtaattcaa ttaaaaagtt taattgcaat
     8821 gagctttatt gtattaagtt atactgtctt atctaaaaac agatttagtt ttatggatgc
     8881 tgcattttgc ttaatgtctg tggcttatgt aggcattggt tttatgttct tttatgaaac
     8941 gagatcagaa ggattacatt acatattata tgccttttta attgtttggc ttacagatac
     9001 aggggcttac ttatttggta aaatgatggg caaacataag ctttggccag taataagtcc
     9061 gaataagaca atcgaaggat tcataggtgg cttgttctgt agtttgatag tgcctcttgc
     9121 aatgttatat tttgtagatt tcaatatgaa tgtatggata ttacttggag tgacattgat
     9181 tttaagttta tttggtcaat taggtgattt agtggaatca ggatttaagc gtcatttcgg
     9241 cgttaaagac tcaggtcgaa tactacctgg acacggtggt attttagacc gatttgacag
     9301 ctttatgttt gtgttaccat tattaaatat tttattaata caatcttaat gctgagaaca
     9361 aatcaataaa cgtaaagagg agttgctgag ataatttaat gaatctcaga actccttttg
     9421 aaaattatac gcaatattaa ctttgaaaat tagacgttat attttgtgat ttgtcagtat
     9481 catattataa tgacttatgt tacgtataca gcaatcaatt ttaaaataaa agaaatttat
     9541 aaacaatcga ggtgtagcga gtgagctatt tagttacaat aattgcattt attattgttt
     9601 ttggtgtact agtaactgtt catgaatatg gacatatgtt ttttgcgaaa agagcaggca
     9661 ttatgtgtcc agaatttgcg atcggtatgg ggccaaaaat ttttagtttt agaaaaaatg
     9721 aaacacttta cactattagg ttattgcctg ttggtggata tgttcgtatg gcaggagatg
     9781 gcttagaaga gccaccagtc gagcccggta tgaacgttaa aattaaactg aatgaagaaa
     9841 atgaaataac acatatcata ttagatgatc atcataagtt tcaacaaatt gaagcgatcg
     9901 aagttaaaaa atgtgatttt aaggatgact tattcataga aggtatcact gcttatgata
     9961 atgaaagaca tcattttaaa attgctagaa agtctttctt tgttgaaaat ggtagcttag
    10021 ttcaaattgc tccgagagac agacaatttg cacataaaaa gccatggccg aaatttttaa
    10081 cattatttgc gggaccgtta tttaacttta tattagcttt agtcctattt attggtcttg
    10141 catattatca aggtacacct acgtctactg tagaacaagt cgcagataag tatccagctc
    10201 aacaagcagg attacaaaaa ggtgataaaa ttgttcaaat tggcaaatat aaaatatctg
    10261 aatttgatga tgttgataag gcgttagata aagttaaaga taataagacg actgttaaat
    10321 ttgaacgtga tggtaaaacg aagtcagttg aattaacacc taaaaagact gaaagaaaac
    10381 tgactaaagt aagttcagag acgaagtatg ttctcggatt ccaaccagcg agtgaacata
    10441 cacttttcaa accaattgta tatggatttg aaagcttttt gaaaggtagt acactaattt
    10501 ttacagctgt agtcggtatg ttggctagta tatttacggg cggattctca tttgatatgt
    10561 taaatggtcc ggttggtatt tatcataacg tcgactcagt tgttaaagcg ggtatcatta
    10621 gcttaattgg ttacactgcg ttattaagtg taaacttagg tattatgaat ttaattccta
    10681 ttcctgcact agacggtggt cgtattttat ttgttatata tgaagcgatt ttcagaaaac
    10741 cagttaataa aaaagcggaa acaacgatta ttgctattgg tgccattttc atggtcgtta
    10801 ttatgatatt agtaacgtgg aatgatattc gacgatattt cttataattt aggaggataa
    10861 ataattatga agcaatccaa agtttttata ccaacgatgc gtgatgtgcc atcagaagca
    10921 gaagcacaaa gtcatcgttt attattgaaa tcgggtttga taaaacaaag tacaagtggg
    10981 atttatagtt atttaccgct agcaacacgt gtgttaaata atattactgc aattgtgcga
    11041 caagaaatgg aacgtatcga ttctgttgaa attttaatgc cagcgttaca acaagctgaa
    11101 ttatgggaag aatcaggacg ttggggtgca tatggcccag aattaatgcg tttacaagat
    11161 agacatggaa gacaatttgc attaggtcca acacatgaag aattagttac atcaatagta
    11221 agaaatgaat tgaaatcata caaacaatta ccgatgacat tattccaaat tcaatctaaa
    11281 ttccgtgatg aaaagagacc acgttttggt ttacttcgtg ggcgtgaatt tattatgaaa
    11341 gatgcgtatt cattccatgc tgacgaggca tcattagatc aaacgtatca agatatgtat
    11401 caagcgtata gccgtatttt tgagagagtt ggcattaatg ctagaccagt tgtagcagat
    11461 tcaggtgcta taggcggtag ccatacacat gaatttatgg cattaagtgc tatcggtgag
    11521 gatacaatcg tttacagtaa agaaagtgac tatgctgcta atatcgaaaa agcagaagtc
    11581 gtttacgaac caaatcataa gcattctact gtgcaacctt tagaaaaaat tgaaacacca
    11641 aatgttaaga ctgcacaaga attggcagac ttcttaggta gaccagtaga tgaaatcgtt
    11701 aaaacgatga ttttcaaagt tgatggcgaa tatattatgg ttttagtgcg tggccatcat
    11761 gaaattaatg acattaaatt aaaatcttat ttcggcacag ataatattga attagcaaca
    11821 caagacgaaa ttgttaattt agttggtgca aatccgggtt cactaggtcc tgttattgat
    11881 aaagaaatca aaatttatgc agataatttt gtgcaagatt taaataattt agttgtcggt
    11941 gctaacgaag atggctatca cttaattaat gtaaatgtag gtagagactt caacgttgat
    12001 gaatatggcg atttccgttt tattttagaa ggcgaaaagt taagtgatgg ttcaggcgtt
    12061 gcacattttg ctgaaggtat tgaagttggt caagtattca aattgggtac taagtattca
    12121 gaatcaatga atgctacatt cttagataac caaggaaaag ctcaaccttt aattatgggc
    12181 tgttacggta ttggaatttc tagaacgcta agtgcgattg ttgaacaaaa tcacgatgat
    12241 aatggaattg tttggcctaa atcagttact ccatttgatt tacatttaat ttctattaat
    12301 cctaagaaag atgatcaacg agagctagca gatgcactat atgctgaatt taatactaaa
    12361 tttgatgtgt tgtacgatga tcgtcaggaa cgtgcaggtg tcaaatttaa tgatgccgat
    12421 ttaattggtt taccactgcg aattgttgtt ggtaaacgtg catcggaagg tattgtagaa
    12481 gttaaagaac gtttaacagg tgatagcgaa gaagttcaca ttgatgactt aatgactgtc
    12541 attacaaata aatatgataa cttaaaataa ttaagatcga atgaattata agagtaggaa
    12601 aaagctgaaa gaaatctgat gcttatgtcc tgctcttatt atttttgata taatgattat
    12661 tcgatgaaaa atgactgaag acatagtata attaaagata aatttgtttt aacaatatta
    12721 tgattagcca aatataaagc atttaatttt ctatcattac tatgctcaca taatctaaat
    12781 attgttcgaa cacgtaaaag taatttctat ttaaggtggt aattgtcttg gcaatgacag
    12841 agcaacaaaa atttaaagtg cttgctgatc aaattaaaat ttcaaatcaa ttagatgctg
    12901 aaattttaaa ttcaggtgaa ctgacacgta tagatgtttc taacaaaaac agaacatggg
    12961 aatttcatat tacattacca caattcttag ctcatgaaga ttatttatta tttataaatg
    13021 caatagagca agagtttaaa gatatcgcca acgttacatg tcgttttacg gtaacaaatg
    13081 gcacgaatca agatgaacat gcaattaaat actttgggca ctgtattgac caaacagctt
    13141 tatctccaaa agttaaaggt caattgaaac agaaaaagct tattatgtct ggaaaagtat
    13201 taaaagtaat ggtatcaaat gacattgaac gtaatcattt tgataaggca tgtaatggaa
    13261 gtcttatcaa agcgtttaga aattgtggtt ttgatatcga taaaatcata ttcgaaacaa
    13321 atgataatga tcaagaacaa aacttagctt ctttagaagc acatattcaa gaagaagacg
    13381 aacaaagtgc acgattggca acagagaaac ttgaaaaaat gaaagctgaa aaagcgaaac
    13441 aacaagataa caacgaaagt gctgtcgata agtgtcaaat tggtaagccg attcaaattg
    13501 aaaatattaa accaattgaa tctattattg aggaagagtt taaagttgca atagagggtg
    13561 tcatttttga tataaactta aaagaactta aaagtggtcg tcatatcgta gaaattaaag
    13621 tgactgacta tacggactca ttagttttaa aaatgtttac tcgtaaaaac aaagatgatt
    13681 tagaacattt taaagcgcta agtgtaggta aatgggttag ggctcaaggt cgtattgaag
    13741 aagatacatt tattagagat ttagttatga tgatgtctga tattgaagag attaaaaaag
    13801 cgacaaaaaa agataaggct gaagaaaagc gtgtagaatt ccacttgcat actgcaatga
    13861 gccaaatgga tggtataccc aatattggtg cgtatgttaa acaggcagca gactggggac
    13921 atccagccat tgcggttaca gaccataatg ttgtgcaagc atttccagat gctcacgcag
    13981 cagcggaaaa acatggcatt aaaatgatat acggtatgga aggtatgtta gttgatgatg
    14041 gtgttccgat tgcatacaaa ccacaagatg tcgtattaaa agatgctact tatgttgtgt
    14101 tcgacgttga gacaactggt ttatcaaatc agtatgataa aatcatcgag cttgcagctg
    14161 tgaaagttca taacggtgaa atcatcgata agtttgaaag gtttagtaat ccgcatgaac
    14221 gattatcgga aacgattatc aatttgacgc atattactga tgatatgtta gtagatgccc
    14281 ctgagattga agaagtactt acagagttta aagaatgggt tggcgatgcg atattcgtag
    14341 cgcataatgc ttcgtttgat atgggcttta tcgatacggg atatgaacgt cttgggtttg
    14401 gaccatcaac gaatggtgtt atcgatactt tagaattatc tcgtacgatt aatactgaat
    14461 atggtaaaca tggtttgaat ttcttagcta aaaaatatgg cgtagaatta acgcaacatc
    14521 accgtgccat ttatgataca gaagcaacag cttacatttt cataaaaatg gttcaacaaa
    14581 tgaaagaatt aggtgtatta aatcataacg aaatcaacaa aaaactcagt aatgaagatg
    14641 catataaacg tgcaagacct agccatgtca cattaattgt acaaaaccaa caaggtctta
    14701 aaaatctatt taaaattgta agtgcatcat tggtgaagta tttctaccgt acacctcgaa
    14761 ttccacgttc attgttagat gaatatcgtg agggattatt ggtaggtaca gcgtgtgatg
    14821 aaggtgaatt atttacggca gttatgcaga aggaccagag ccaagttgaa aaaattgcca
    14881 aatattatga ttttattgaa attcaaccac cggcacttta tcaagattta attgatagag
    14941 agcttattag agatactgaa acattacatg aaatttatca acgtttaata catgcaggtg
    15001 acacagcggg tatacctgtt attgcgacag gaaatgcaca ctatttgttt gaacatgatg
    15061 gtatcgcacg taaaatttta atagcatcac aacccggcaa tccacttaat cgctcaactt
    15121 taccggaagc acattttaga actacagatg aaatgttaaa cgagtttcat tttttaggtg
    15181 aagaaaaagc gcatgaaatt gttgtgaaaa atacaaacga attagcagat cgaattgaac
    15241 gtgttgttcc tattaaagat gaattataca caccgcgtat ggaaggtgct aacgaagaaa
    15301 ttagagaact aagttataca aatgcgcgta aactgtatgg tgaagacctg cctcaaatcg
    15361 taattgatcg attagaaaaa gaattaaaaa gtattatcgg taatggattt gcggtaattt
    15421 acttaatttc gcaacgttta gttaaaaaat cattagatga tggatactta gttggttccc
    15481 gtggttcagt aggttctagt tttgtagcga caatgactga gattactgaa gtaaacccgt
    15541 taccgccaca ctatatttgt ccgaactgta aaacgagtga atttttcaat gatggttcag
    15601 taggatcagg attcgattta cctgataaga cgtgtgaaac ttgtggagcg ccacttatta
    15661 aagaaggaca agatattccg tttgaaacat ttttaggatt taagggagat aaagttcctg
    15721 atatcgactt aaactttagt ggtgaatatc aaccgaatgc ccataactac acaaaagtat
    15781 tatttggtga ggataaagta ttccgtgcag gtacaattgg taccgttgct gaaaagactg
    15841 cttttggtta tgttaaaggt tatttgaatg atcaaggcat ccacaaaaga ggcgctgaaa
    15901 tagatcgact cgttaaagga tgtacaggtg ttaaacgtac aactggacag catccaggag
    15961 gtattattgt agtacctgat tacatggata tttatgattt tacgccgata caatatcctg
    16021 ccgatgatca aaattcagca tggatgacga cacattttga tttccattct attcatgata
    16081 atgtattaaa acttgatata cttggacacg atgatccaac aatgattcgt atgcttcaag
    16141 atttatcggg cattgatcca aaaacgatac ctgtagatga caaagaagtc atgcaaatat
    16201 ttagtacacc tgaaagttta ggtgttactg aagatgaaat tttatgtaaa acaggtacgt
    16261 ttggggttcc agaattcggt acagggttcg tgcgtcaaat gttagaagat acaaagccaa
    16321 caacattttc tgaattagtt caaatctcag gattatctca tggtacagat gtgtggttag
    16381 gcaatgctca agaattaatt aaaaccggta tatgtgattt atcaagtgta attggttgtc
    16441 gtgatgatat catggtttat ttaatgtatg ctggtttaga accatcaatg gcttttaaaa
    16501 taatggagtc agtacgtaaa ggtaaaggtt taactgaaga aatgattgaa acgatgaaag
    16561 aaaatgaagt gccggattgg tatttagatt catgtcttaa aattaagtac atgttcccta
    16621 aagcccatgc agcagcatac gttttaatgg cagtacgtat cgcatatttc aaagtacatc
    16681 atccacttta ttactatgca tcttacttta caattcgtgc gtcagatttt gatttaatca
    16741 cgatgattaa agataaaaca agcattcgaa atactgtaaa agacatgtat tctcgctata
    16801 tggatctagg taaaaaagaa aaagacgtat taacagtctt ggaaattatg aatgaaatgg
    16861 cgcatcgagg ttatcgaatg caaccgatta gtttagaaaa gagtcaggcg ttcgaattta
    16921 tcattgaagg cgatacactt attccgccgt tcatatcagt gcctgggctt ggcgaaaacg
    16981 ttgcgaaacg aattgttgaa gctcgtgacg atggcccatt tttatcaaaa gaagatttaa
    17041 acaaaaaagc tggattatct cagaaaatta ttgagtattt agatgagtta ggctcattac
    17101 cgaatttacc agataaagct caactttcga tatttgatat gtaaaatgaa ataatcaagg
    17161 tatttattta atgcgtatgg cgtagttaaa gaaatacaaa attggtgctg gacataaaat
    17221 tatgcctgta tttcttttca acgtcttacg agtctattcg aatgtaatgg tgaaataaat
    17281 gaacaaactt ttacaagaat ctctgattaa tagtgaagtc atttgtttca agcataaact
    17341 tatgctataa ttaagttgct taaaaattag tgaactcagg cagaagagtg ggagattccc
    17401 gctcttttct atttgccaaa aagggaggcc tgtatgagta aaattacaga acaagtagaa
    17461 gtgattgttc aaccaattat ggaagacttg aattttgaac ttgtagacgt tgaatatgtc
    17521 aaagagggta gagatcattt tcttagaatc tctattgata aagaaggtgg cgtagattta
    17581 aatgattgta cgctagcttc tgaaaaaata agtgaagcta tggatgcaaa tgatcctatt
    17641 cctgaaatgt attatttaga cgtagcgtca cctggtgcag aacgtccaat taaaaaagaa
    17701 caagatttcc aaaatgcaat aactaaacct gtatttgttt ctttatatgt accaattgaa
    17761 ggtgaaaagg aatggttagg cattttacaa gaagtcaata atgaaacaat tgtagtacaa
    17821 gttaaaatca aagcaagaac gaaagatata gagataccga gagacaaaat agcaaaagca
    17881 cgtcacgcag ttatgattta acgtgatgag gaggaaaaaa cgtgtcaagt aatgaattat
    17941 tattagctac tgagtattta gaaaaagaaa agaagattcc tagagcagta ttaattgatg
    18001 ctattgaagc agctttaatt actgcataca aaaagaatta tgatagtgca agaaatgtcc
    18061 gtgtggaatt aaatatggat caaggtactt tcaaagttat cgctcgtaaa gatgttgttg
    18121 aagaagtatt tgacgacaga gatgaagtgg atttaagtac agcgcttgtt aaaaaccctg
    18181 catatgaaat tggtgatata tacgaagaag atgtaacacc taaagatttt ggtcgtgtag
    18241 gtgctcaagc agcgaaacaa gcagtaatgc aacgtcttcg tgatgctgaa cgtgaaattt
    18301 tatttgaaga atttatagac aaagaagaag acatacttac tggaattatt gaccgtgttg
    18361 accatcgtta tgtatatgtg aatttaggtc gtatcgaagc tgttttatct gaagcagaaa
    18421 gaagtcctaa cgaaaaatat attcctaacg aacgtatcaa agtatatgtt aacaaagtgg
    18481 aacaaacgac aaaaggtcct caaatctatg tttctcgtag ccatccaggt ttattaaaac
    18541 gtttatttga acaagaagtt ccagaaattt acgatggtac tgtaattgtt aaatcagtag
    18601 cacgtgaagc tggcgatcgc tctaaaatta gtgtcttctc tgaaaacaat gatatagatg
    18661 ctgttggtgc atgtgttggt gctaaaggcg cacgtgttga agctgttgtt gaagagctag
    18721 gtggcgaaaa aatcgacatc gttcaatgga atgaagatcc aaaagtattt gtaaaaaatg
    18781 ctttaagccc ttctcaagtt ttagaagtta ttgttgatga aacaaatcaa tctacagtag
    18841 ttgttgttcc tgattatcaa ttgtcattag cgattggtaa aagaggacaa aacgcacgtc
    18901 tagctgctaa attaaccggc tggaaaattg atattaaatc agaaacagat gcgcgtgaag
    18961 cgggtatcta tccagtagtt gaagctgaaa aagtaactga agaagatatt gctttagaag
    19021 atgctgacac aacagaatca accgaagagg taaatgatgt ttcagttgaa acaaatgtag
    19081 agaaagaatc tgaataatag gttggagtga agtatctatg aaaaagaaaa aaattccgat
    19141 gcgaaaatgt attctttcaa atgaaatgca tcccaaaaaa gatatgattc gtgttgttgt
    19201 taataaagaa ggcgaaatct ttgcggatgt tactggaaag aaacaaggcc gtggcgcata
    19261 tgtttctaaa gatgttgcta tggttgaaaa agcacaacaa aaagaaattt tagaaaaata
    19321 ttttaaagca tctaaagagc aattggatcc tgtttacaaa gaaattatta gattaattta
    19381 tagagaagag attccaaaat gagtatagat caaatattaa actttttagg attagcaatg
    19441 agagctggta aagtaaaaac aggtgaatca gtcattgtta atgagattaa aaaaggaaat
    19501 ttgaagctcg ttattgttgc aaatgatgcg tctgataata cagctaaatt aattacagat
    19561 aaatgtaaga gttacaaagt tccattcaga aagtttggaa atcgaaatga attgggaata
    19621 gcacttggaa aaggtgagcg tgttaatgta gggattactg acccaggctt tgctaaaaag
    19681 ttgctatcaa tgatagatga atatcataag gagtgattat atgagtaaac aaagaattta
    19741 cgaatatgcg aaagaattaa atctaaagag taaagagatt atagatgagt taaaaagcat
    19801 gaatatagag gtttcaaatc atatgcaagc tttggaagat gaccaaatta aagcattaga
    19861 taaaaagttc aaaaaagaac aaaagaacga caataaacaa agcactcaaa ataatcacca
    19921 aaaatcaaac aatcaaaacc aaaataaagg gcaacaaaaa gataacaaaa agaatcaaca
    19981 acaaaataat aaaggcaaca aaggcaataa aaagaataat agaaataata agaaaaataa
    20041 caagaataat aaaccacaaa atcaaccagc tgctccaaaa gaaataccat caaaagtgac
    20101 atatcaagaa ggtattacag taggcgaatt tgcggataaa ttaaatgttg aatcatcaga
    20161 aattatcaaa aaattattct tacttggtat tgttgctaat atcaatcaat cattaaatca
    20221 agaaacaatc gaattaattg ccgatgatta tggcgttgag gttgaagaag aagttgtgat
    20281 taatgaagaa gatttatcaa tctacttcga agacgaaaaa gatgatccag aagcaattga
    20341 gagaccagca gttgtaacaa ttatgggaca tgttgaccat ggtaaaacga ctttattaga
    20401 ttcaattcgt catacaaaag ttacagcagg tgaagcaggc ggaatcactc aacatattgg
    20461 tgcatatcaa attgaaaacg atggcaaaaa aatcactttc ttagatacac cgggacatgc
    20521 tgcatttaca acgatgcgtg cgcgtggtgc acaagtaaca gatattacaa ttttagtagt
    20581 agcagctgac gatggtgtta tgccacaaac aattgaagca attaaccatg ctaaagaagc
    20641 agaagtacca attattgttg cagtaaataa aattgataaa ccaacttcaa atcctgatcg
    20701 agttatgcaa gaattaactg aatatggttt aattcctgaa gattggggcg gcgaaacaat
    20761 tttcgttcca ctttctgcat taagtggtga tggtatcgac gatttattag aaatgatagg
    20821 attagttgca gaagttcaag aacttaaagc aaatcctaaa aaccgtgctg ttggtacagt
    20881 tatcgaagct gaattagata aatcacgtgg tccttctgca tcattattag tacaaaacgg
    20941 tacattaaat gttggtgatg cgattgtagt tggtaatact tacggccgta tccgtgcaat
    21001 ggttaatgac ttaggtcaaa gaatcaaaac ggctggtcca tcaacgcctg ttgaaattac
    21061 aggtattaat gatgtgccac aagctgggga tcgctttgtt gtatttagtg atgaaaaaca
    21121 agctcgtcgt attggtgaat caagacacga agctagcatt gtacaacaac gtcaagaaag
    21181 taaaaatgtt tcattagata acctgtttga acaaatgaaa caaggtgaaa tgaaagattt
    21241 aaacgttatt attaaaggtg atgttcaagg ttctgttgaa gctttagctg catcattaat
    21301 gaaaattgat gttgaaggcg taaatgttcg tatcattcat acagcggttg gtgcaattaa
    21361 tgagtcagac gtgacacttg ctaatgcctc aaatggtatt atcattggtt tcaatgttcg
    21421 tccagacagt ggtgcaaaac gtgctgcaga agctgaaaat gttgatatgc gtttacacag
    21481 agttatttat aatgttatcg aagaaattga atcagcgatg aaaggtttac ttgatccaga
    21541 atttgaagaa caagttatcg gacaagctga agttcgtcaa acattcaaag tttctaaagt
    21601 tggtactatt gctggatgtt atgttactga aggtaaaatt acgcgaaatg ctggtgtacg
    21661 tattattcgt gatggtattg ttcaatatga aggcgaatta gatacactta aacgtttcaa
    21721 agatgatgct aaggaagttg caaaaggtta tgaatgtggt attacaattg aaaactacaa
    21781 tgaccttaaa gaaggcgatg ttatcgaagc atttgaaatg gttgaaatta agcgttaatt
    21841 aaataaatta caagctaaaa gtatagttaa gattgatatg ctccctataa atattgcact
    21901 ttttaagtgt ctactttata gggagcatat ttgatactag cttttggttt tttattagaa
    21961 tagattacct attaaaagtt acgttatatg gacatgattt tgtataaaat tttgtggtgg
    22021 cctagaatga tttttaatga caaaatataa tgtcgactat tattggaaaa ttttctgttg
    22081 aaatgcctat cttacggcaa actttatttg attttatagg cttaatttat taaaataacg
    22141 tgtgagctaa aataattgtt taagcattgt tacactaaaa aatgcaaata acaattgaac
    22201 ttaaagataa agaggtgaca agaatgagca gtatgagagc agagcgtgtt ggtgaacaaa
    22261 tgaagaagga attaatggat atcatcaaca ataaagtcaa agatcctcga gttggtttta
    22321 ttacaattac agatgttgtt ttaacaaatg atttatcgca ggctaaagta tttttaactg
    22381 tattaggtaa cgataaagaa gtagaaaata catttaaagc acttgataaa gcaaaaggct
    22441 tcattaagtc tgaattaggt tctagaatgc gattacgtat tatgccggaa ttaatgtatg
    22501 aatatgatca atcaatcgaa tatggtaata aaattgaacg aatgattcaa gatttacaca
    22561 aacaagatag ataatttagt gttaggtatc tggaaaatgt ttgataattt cttaatatcg
    22621 gtatattaac attaaacagt taatacatag atgtgtagaa atagttaaca ttttccagtt
    22681 tttttatgaa taaattcagt tgatacgcta ttaaaatata ttttaaaaaa gaaggtgact
    22741 atatgtataa tgggatatta ccagtatata aagagcgcgg tttaacaagt catgacgttg
    22801 tattcaaatt gcgtaaaata ttaaaaacta aaaaaatagg tcacacgggt acgcttgatc
    22861 ccgaagttgc aggcgtgtta ccggtatgta taggtaatgc aacgagagtt agtgattatg
    22921 ttatggatat gggcaaagct tatgaagcaa ctgtatcgat aggaagaagt acaacgactg
    22981 aagatcaaac gggtgataca ttggaaacaa aaggtgtaca ctcagcagat tttaataagg
    23041 acgatattga ccgattgtta gaaaatttta aaggtgttat tgaacaaatt ccgccaatgt
    23101 attcatcagt caaggtgaat ggcaaaaaat tatatgaata tgcgcgtaat aatgaaacag
    23161 ttgaaagacc aaagcgtaaa gttaatatta aagacattgg gcgtatatct gaattagatt
    23221 ttaaagaaaa tgagtgtcat tttaaaatac gcgtcatctg tggtaaaggt acatatatta
    23281 gaacgctagc aactgatatt ggtgtgaaat taggctttcc ggcacatatg tcgaaattaa
    23341 cacgaatcga gtctggtgga tttgtgttga aagatagcct tacattagaa caaataaaag
    23401 aacttcatga gcaggattca ttgcaaaata aattgtttcc tttagaatat ggattaaagg
    23461 gtttgccaag cattaaaatt aaagattcgc acataaaaaa acgtatttta aatgggcaga
    23521 aatttaataa aaatgaattt gataacaaaa ttaaagacca aattgtattt attgatgatg
    23581 attcagaaaa agtattagca atttatatgg tacaccctac aaaagaatca gaaattaaac
    23641 ctaaaaaagt ctttaattaa aggagataga atttatgaaa gtcatagaag tgacacatcc
    23701 tatacaatct aaacagtata ttacagagga tgttgcaatg gcattcggat ttttcgatgg
    23761 catgcataaa ggtcatgaca aagtctttga tatattaaat gaaatagctg aggcacgcag
    23821 tttaaaaaaa gcggtgatga catttgatcc gcatccgtct gtcgtgttga atcctaaaag
    23881 aaaacgaaca acgtatttaa caccactttc agataaaatc gaaaaaatta gccaacatga
    23941 tattgattat tgtatagtgg ttaatttttc atctaggttt gctaatgtga gcgttgaaga
    24001 ttttgttgaa aattatataa ttaaaaataa tgtaaaagaa gtcattgctg gttttgattt
    24061 tacttttggt aaatttggaa aaggtaatat gactgttctt caagaatatg atgcgtttaa
    24121 tacgacaatt gtgagtaaac aagaaattga aaatgaaaaa atttctacaa cttctattcg
    24181 tcaagattta atcaatggtg agttgcaaaa agcgaatgat gctttaggct atatttattc
    24241 tattaaaggc actgtagtgc aaggtgaaaa aaggggaaga actattggct tcccaacagc
    24301 taacattcaa cctagtgatg attatttgtt acctcgtaaa ggtgtttatg ctgttagtat
    24361 tgaaatcggc actgaaaata aattatatcg aggggtagct aacataggtg taaagccaac
    24421 atttcatgat cctaacaaag cagaagttgt catcgaagtg aatatctttg actttgagga
    24481 taatatttat ggtgaacgag tgactgtgaa ttggcatcat ttcttacgtc ctgagattaa
    24541 atttgatggt atcgacccat tagttaaaca aatgaacgat gataaatcgc gtgctaaata
    24601 tttattagca gttgattttg gtgatgaagt agcttataat atctagagtt gcgtatagtt
    24661 atataaacaa tctataccac acctttttct tagtaggtcg aatctccaac gcctaactcg
    24721 gattaaggag tattcaaaca ttttaaggag gaaattgatt atggcaattt cacaagaacg
    24781 taaaaacgaa atcattaaag aataccgtgt acacgaaact gatactggtt caccagaagt
    24841 acaaatcgct gtacttactg cagaaatcaa cgcagtaaac gaacacttac gtacacacaa
    24901 aaaagaccac cattcacgtc gtggattatt aaaaatggta ggtcgtcgta gacatttatt
    24961 aaactactta cgtagtaaag atattcaacg ttaccgtgaa ttaattaaat cacttggtat
    25021 ccgtcgttaa tcttaatata acgtctttga ggttggggca tatttatgtt ccaaccttaa
    25081 tttatattaa aaaagctttt tacaaatatt aacatttatt atatgttaag ctaatattga
    25141 gtgaataata aggttacaat gagataaaga tgatataagt acacctagag taataatcaa
    25201 gatattaaaa ataaagtatg ttttttaaaa aatataactt atatttatac tgataagggt
    25261 gggacgataa gtctattttg taaataatag atggatatcc cgctctcttt ttttccaatt
    25321 caatatttta taactaatat taaaatacga taataaatga tatgatataa ctattagatt
    25381 caagagagga gatttataat gtctcaagaa aagaaagttt ttaaaactga atgggcagga
    25441 agatctttaa cgattgaaac agggcaatta gctaaacaag caaatggcgc tgtattggtt
    25501 cgttatggag atacagtcgt gttatcgacg gcaactgcat caaaagaacc tcgtgatgga
    25561 gatttcttcc cattaacagt gaactacgaa gaaaaaatgt acgctgcggg taaaattcct
    25621 ggtggattta aaaagagaga aggacgtcct ggtgacgatg caacattaac tgcgcgatta
    25681 attgatagac caattagacc tttattccct aaagggtata agcatgatgt tcaaattatg
    25741 aacatggtat taagtgcaga tcctgattgt tcaccacaaa tggctgcaat gattggttca
    25801 tctatggcgc ttagtgtgtc ggatattcca ttccaagggc caatcgccgg tgtaaatgtg
    25861 ggttatattg atggtaaata tatcattaac ccaacagtag aagaaaaaga agtttctcgt
    25921 ttagaccttg aagtagctgg tcataaagat gcagtaaaca tggtagaggc aggcgctagt
    25981 gagattactg aacaagaaat gttagaggcg attttctttg gtcatgaaga gattcaacgt
    26041 ttagttgatt tccaacaaca aatcgtcgac cacattcaac ctgttaaaca agaatttatt
    26101 ccagcagagc gtgatgaagc gctagttgaa cgtgtgaaat ctttaaccga agaaaaggga
    26161 cttaaagaaa cagttttaac atttgataaa caacaacgag atgaaaatct tgataactta
    26221 aaagaagaaa tcgtcaatga atttatcgat gaagaagatc cagagaatga attacttatt
    26281 aaagaagttt atgcaatttt aaatgaatta gtgaaagaag aagttcgacg tttaattgca
    26341 gatgaaaaaa ttagaccaga cggccgtaaa cctgatgaaa tccgtccatt agattctgaa
    26401 gttggtattt tacctagaac gcatggttca ggtctattta cacgtggtca gactcaagca
    26461 ctttcagttt taacattagg tgctttaggc gattatcaat taattgatgg tttaggacct
    26521 gaagaagaaa aaagattcat gcatcattat aacttcccga acttttcagt aggtgaaact
    26581 ggtccagtac gtgcgccagg tcgtcgtgaa attggacatg gtgcgttagg tgaaagagca
    26641 ttaaaatata ttattcctga tactgctgat ttcccatata caattcgtat tgtaagtgag
    26701 gtacttgaat caaacggttc atcatctcaa gcgtcaattt gtggatcaac cttagcatta
    26761 atggatgcgg gcgtaccgat taaagcacca gttgctggta ttgctatggg ccttgttaca
    26821 cgtgaagata gctatacgat tttaactgat atccaaggta tggaagatgc attaggtgat
    26881 atggacttta aagtcgctgg tactaaagaa ggtattacag caatccaaat ggatattaaa
    26941 attgacggtt taacgcgtga aattatcgaa gaggctctag aacaagcgag acgtggtcgt
    27001 ttagaaataa tgaatcatat gttacaaaca attgatcaac cacgtactga attaagtgct
    27061 tacgcgccaa aagttgtaac tatgacaatt aaaccagata agattagaga tgttatcgga
    27121 cctggtggta aaaaaattaa cgaaattatt gatgaaacag gcgttaaatt agatattgaa
    27181 caagatggta ctatctttat tggggccgtt gatcaagcta tgataaatcg tgctcgtgaa
    27241 atcattgagg aaattacacg tgaagcggaa gtaggtcaaa cttatcaagc cactgttaaa
    27301 cgtattgaaa aatacggtgc gtttgtaggc ctattcccgg gtaaagatgc gttgcttcac
    27361 atttcacaaa tttcaaaaaa tagaattgaa aaagtggaag atgttttaaa aatcggtgac
    27421 acaattgaag ttaagattac tgaaattgat aaacaaggtc gagtaaatgc atcacacaga
    27481 gcattagaag aataatattt aaagtcatat gacgacaatg tatcgtcatg tgattttttt
    27541 atgccatttt ttacgaagtg atccattttg aatttgttgt attgaacatt ttaaaacgct
    27601 ttattatttt gagtgcaact gttaattatc ctgtatgtat agtgattaat agtgtacatc
    27661 aagtgttttt taacttataa tgaatagtga gtttatatat ggacgggtaa caaatttagg
    27721 aggtaagatt ttgagtttaa taaagaaaaa gaataaagat attcgcatta taccattagg
    27781 cggtgttggc gaaattgcta aaaatatgta tatcgttgaa gtagacgatg aaatgtttat
    27841 gttagatgct ggacttatgt ttccagaaga cgaaatgcta ggtattgata ttgttatacc
    27901 agacatttca tacgtacttg aaaataaaga taaattgaag ggtatattcc ttacacacgg
    27961 acatgagcac gcgattggtg cagtgagtta tgttttagaa caattagatg caccagtata
    28021 tggatctaaa ttgacaatag cgttaattaa agaaaatatg aaagcccgta atattgataa
    28081 aaaagttcgc tactacacag ttaacaatga ttcaattatg agattcaaaa acgtgaatat
    28141 tagtttcttt aatacgacac acagtattcc tgatagttta ggtgtttgta ttcacacttc
    28201 atatggtgcc attgtgtata caggtgaatt taagtttgac caaagtttac atggacatta
    28261 tgcaccagat attaaacgta tggcagagat tggtgaagaa ggcgtatttg tcttaatcag
    28321 tgattctact gaggcagaga aacctggata taatactccg gaaaatgtaa ttgaacatca
    28381 tatgtatgat gcttttgcaa aagtgcgagg tcgcttgatt gtttcatgtt atgcttcgaa
    28441 ctttatacgt attcagcaag ttttaaatat tgctagcaag ctaaatcgta aagtgtcatt
    28501 tttaggaaga tcacttgaaa gttcatttaa tattgctcgt aaaatggggt atttcgacat
    28561 tcctaaagat ttgctaattc ctataacaga agttgataat tatcctaaaa atgaagtgat
    28621 aattatagct actggtatgc aaggagaacc tgtagaagcc ttaagtcaaa tggcgcaaca
    28681 taagcataaa attatgaata tcgaagaagg cgattctgta tttttagcaa ttacggcttc
    28741 tgctaatatg gaagttatca ttgcgaatac attaaatgag cttgtacgtg ctggcgcaca
    28801 tattattcca aataacaaga agattcatgc ttcaagtcat ggttgcatgg aagaattaaa
    28861 aatgatgatt aatattatga aacctgaata ctttattcct gtacaaggtg aatttaaaat
    28921 gcagatagca catgcgaagc tagcagctga agcaggtgtt gcaccggaaa agattttcct
    28981 tgtggaaaaa ggagatgtca ttaattacaa cggtaaagat atgatattaa atgaaaaggt
    29041 aaattcggga aatattttaa tagatggtat tggtattggg gatgtaggaa atatcgtgtt
    29101 gagagaccgt catcttttag cagaagatgg tatctttatt gctgtagtaa cgttagatcc
    29161 taaaaataga cgtatagctg cgggtcctga aattcaatct cgtgggtttg tatatgtacg
    29221 tgaaagtgaa gacttattac gtgaagcaga agagaaagta cgtgaaatag tagaagctgg
    29281 tttacaagaa aaacgcatag aatggtctga aattaagcaa aatatgcgtg atcaaattag
    29341 taaactatta ttcgaaagta caaaacgtcg tcctatgatt attccagtaa tttctgaaat
    29401 ttaatcaaaa agtcattaac ataaaagagg tcagaacaag tcaccgaaat ataatggttg
    29461 tcatggacaa tttacttata ttttatgatg gtcaattgaa aggggtaacg attaatctgt
    29521 tatcttaagt aaattgatac atagatgata ttgttctaac ctctttcatc gtctgtttgg
    29581 actacatatt ctaaacatca aataggaaat tatatataat aacgtcgttt taactaaggc
    29641 aacataagga ggtgcgtcaa ttggcacaag caaaaaagaa atcgacagct aagaaaaaaa
    29701 cagcatcaaa aaaaagaaca aattcaagga aaaagaagaa tgataatccg atacgttatg
    29761 tcatagctat tttagtagtt gtattaatgg tgttgggtgt tttccaatta ggaataatcg
    29821 gtcgtctaat tgacagcttc tttaattatt tatttgggta cagtagatat ttaacatata
    29881 ttttagtact cttagcaact ggttttatta catactctaa acgtattcct aaaactagac
    29941 gaacggctgg ttcgattgta ttgcaaattg cattgctatt tgtatcacag ttagtttttc
    30001 attttaatag tggtatcaaa gctgaaagag aacctgtact ttcttatgta tatcagtcat
    30061 accaacacag tcattttcca aattttggtg gcggtgtatt aggtttttat ttattagagt
    30121 taagcgtacc tttaatttca ttatttggtg tatgtattat tactatttta ttattatgct
    30181 caagtgttat tttattaaca aaccatcaac atcgtgatgt tgcaaaagtt gcactggaaa
    30241 atataaaagc ttggtttggt tcatttaatg aaaaaatgtc ggaaagaaac caagaaaaac
    30301 aattgaagcg tgaagaaaaa gcgagactta aagaagaaca aaaggcacgt caaaatgaac
    30361 agccacaaat aaaagatgtg agtgatttta cggaagtgcc tcaagaaaga gatattccaa
    30421 tttatgggca tactgaaaat gaaagtaaaa gccagtgtca accaagtcga aaaaaacgag
    30481 tgtttgatgc agagaatagt tcgaataaca tcgtaaatca tcaagcagat cagcaagagc
    30541 aattaacaga acaaactcat aacagtgttg aaagtgaaaa cactattgaa gaagctggtg
    30601 aagttacgaa tgtatcgtat gttgttccac cgttaacttt acttaatcaa cctgcaaaac
    30661 aaaaagcaac atctaaagct gaagtacaac gtaaaggaca agtactagag aatacattaa
    30721 aagattttgg ggtaaatgca aaagtgacac aaattaaaat tggtcctgca gtaactcaat
    30781 atgaaattca accagctcaa ggggttaaag tgagtaaaat tgtaaacttg cataatgata
    30841 ttgcattagc tttagcagca aaagatgtta gaatcgaagc accaatacct ggtcgctctg
    30901 cagtaggtat tgaagtgcca aatgagaaaa tttcattagt ttcactaaaa gaagttttag
    30961 atgaaaaatt cccgtctaat aataaactag aagttggatt aggaagagat atatcaggtg
    31021 atccaattac tgttccacta aatgaaatgc cacacttatt ggtggcagga tcgacgggta
    31081 gtggtaaatc tgtttgtata aatggtatta ttacaagtat tttattaaat gctaagccgc
    31141 atgaagttaa acttatgtta atcgatccga aaatggttga actaaatgtt tataacggaa
    31201 ttccacattt attaattccg gttgttacaa atcctcataa agctgctcaa gctttagaaa
    31261 aaattgtagc tgagatggaa agacgttatg atttattcca acattcatca actagaaata
    31321 ttaaaggtta taacgaatta atccgtaagc aaaatcaaga attagatgag aagcaaccag
    31381 aattacctta tatcgttgtt attgtagatg agcttgcaga tttaatgatg gtagctggta
    31441 aagaagttga aaatgcgatt caacgtatca cacaaatggc acgtgcagca ggtatacatt
    31501 tgattgtagc aacacaaaga ccttctgtgg atgtaattac aggtatcatt aaaaataaca
    31561 ttccatctag aattgctttt gctgtgagtt ctcaaacaga ttcaagaact attattggta
    31621 ctggcggcgc agaaaagtta cttggtaaag gtgacatgtt atacgttgga aatggtgatt
    31681 catcacaaac acgtattcaa ggggcgtttt taagtgacca agaggtgcaa gatgttgtaa
    31741 attatgtagt agaacaacaa caggcaaatt atgtaaaaga aattgaacca gatgcaccag
    31801 tggataaatc ggaaatgaaa agtgaagatg ctttatatga tgaagcgtat ttgtttgttg
    31861 ttgaacaaca aaaggcaagt acatcattgt tacaacgcca atttagaatt ggttataata
    31921 gagcatctag gttgatggat gatttagaac gcaatcaggt aatcggtcca caaaaaggaa
    31981 gcaagcctag acaagtttta atagatctta ataatgacga ggtgtaaaaa aatgtcagaa
    32041 atgaatgcgg tatataacgt taaacaatac attttaaatt tgattaagca aaataaattg
    32101 gaatatggtg accaacttcc aagtaattta tcaattgcca gagaattaaa tgtaaaaacc
    32161 gacgatgttt atgaagcaat tcaggcattg attactgaac aagtcattaa agataatttt
    32221 gaagagggca caagtgttaa atcactgccc cctttctttt atccattgaa tgaacttata
    32281 agtattgggc aaatgattaa aaatgcagga tttgaatgcg gaactgaata cttaaatttt
    32341 gatgagcaac cagcaactat gttagatgca aatttgttga gcgttgaaga aggatatcca
    32401 gtaaccatta tagaacgatt acgaactgcc gatggagaac cggtcgtcta ttgtttagat
    32461 aaaattgcta aaaaagaatt aacatgtaca gagtatcaaa tgagcaatgg atcgatacta
    32521 agtgcgataa aagaacaaag taatcataat atttgttacg ctgatacaga aattgaagcg
    32581 gtaaattatg aacctcgaat atccgaagta ctgaatgctt cgccacacga aggtttgatt
    32641 ttattaaaaa ttacgcacta caatgaatta gatgaaccta ttttgtattc attaaattat
    32701 atgaaaaata gcttagttca atttaaaatc actagaaaaa tatagatgta agaagatata
    32761 gaggaggcta tatatttgag tagacaatct caaccaaata tacatatcaa agtttcacca
    32821 acaactaaat ttaaaacaac tactatagtt tttaaattta tggcaccttt agaatatgac
    32881 acaattacag ctagatcatt attaagcaaa ttattagttc gagcaactaa gaaatggcca
    32941 accgataagt cgtttaataa tcacttagcc gatttatatg gtgcgtatgt gaatagtaca
    33001 atttcaaaat tcaaagatca gcatgtcatt acattttcat tagaaattgt taatgaacgt
    33061 tatttaagaa acggtgaatc attatttaat caaggattag atttattaca agaaatcatt
    33121 tggaatccat taattgaaaa taaagcattc aatgataatt ttgttaacca agagaaaaca
    33181 ttattagcca aaaaaataga agcaatggta gataataaag cacaatattc gtttttaaaa
    33241 ttactcgacc atatgtttga aaatgaagca tataaatact tatctacagg acaactagaa
    33301 caaatcccac atattactgc tgaaacacta tatcatacat atcaatcaat gattaataat
    33361 gatcaatgtt ctgtttatgt tgtcggcaat gtagaacctg aaagtgttga gaaacaaata
    33421 cgtgaaaaat ttgcacttaa accattcgat aaacatcaat tccaacattc tactcatcat
    33481 ttacacgatg aagaagttga ttatattgtt gaatatgatg acgtggatca agctaaatta
    33541 aatatgggat accgttttcc aacacaatat ggacaaagtg gatatgctgc gtttgttgta
    33601 tttaacatga tgtttggagg agatccttca tctgttttat ttaatgaagt gcgagaaaag
    33661 caaagtttag cgtactctat acattcacaa attgatggca aaaatggcta tttatttgtt
    33721 ttgagtgggg tttcaagtga taagtacgaa actgcaaaag acactattat aagtgaattt
    33781 gaaaaaataa aagcaggaga tttcactgaa gaaaaattag agttagctaa aaaagtaatc
    33841 atttctcatc gatatgaatc tgaagatcgt ccgaaaagta ttatagagat tatgcataac
    33901 caaatattat tagagcaacc acaaagcaaa gaaacattta taaatgatat acagaaggta
    33961 agtcgcgaag atattgtttc tgttgctgaa aaagcatttt tagatacaat ctatgtgttg
    34021 acaaaaggag gggataaata atgaaagagc gttattatga attaatagac gaaagagtat
    34081 tcgaacaaga attagaaaat ggtttacgat tatttattat ccccaaacca ggttttcaaa
    34141 agacatttgt cacttacact acacaatttg gttcattaga taatcaattc aaaccccttg
    34201 gacaagacca atttgttact gtacctgatg gagttgctca ctttttagaa cataaattat
    34261 ttgaaaaaga agaagaagac ttatttactg cgtttgctga agataatgca caagcaaatg
    34321 cgtttacaag ctttgatcgt acaagctact tgttcagtgc aactgataat attgaaaaca
    34381 acattaaacg tttacttaca atggttgaaa cgccttattt tacaaaagaa actgttgata
    34441 aagaaaaagg tattattgca gaagaaataa aaatgtatca agaacaacct ggatataaat
    34501 taatgtttaa tacattgcgt gcaatgtatc aacgacatcc aatacgtgtt gatattgccg
    34561 gtagtgtaga aagtatatac gatattacaa aagatgattt gtatctatgt tatgaaacgt
    34621 tttatcatcc atcaaatatg gttttatttg ttgttggtga tgtgaatcca gaagaaatat
    34681 gtcgaatagt aaaacaacac gaggatgctc gtaataaagt taaccaaccc aaaatcgaac
    34741 gaggacttgt tgatgaaccg gaggatgtta aagaagcatt tgttactgaa tctatgaaaa
    34801 ttcaatcacc aagactaatg cttggtttta aaaataaacc attacaagaa gcgcctcaaa
    34861 aatatgtaca acgtgattta gaaatgtcat tattctttga gttaattttt ggggaagaaa
    34921 cagattttta tcagaattta ttaaacgaag gacttatcga tgatacattt ggttatcaat
    34981 ttgtactaga gccgacgtat agtttttcaa tcgtgacaag cgctactgaa gaaccagata
    35041 aattaaaaaa attattatta gatgagttgc gtgataaaaa aggcaatttc caagatgcag
    35101 aagcatttga acttttgaaa aagcaattta taggtgaatt catatcaagt ttaaactcac
    35161 ctgaatatat tgctaatcaa tatactaaat tgtattttga aggtgttagc gtgtttgaca
    35221 tgttagacat tgttgaaaat atcacgttag atagtattaa cgaaacgtca tcgttatatt
    35281 taaatttaga tcagcaagtc gatagtcgtt tggagattaa aaagtaatga aagcattagt
    35341 attaggtggt tctggttcaa ttggttctga gatagtcaaa caattattaa ctgatggatt
    35401 tgaagtttat gtgcaatatt atcgtactga tataaatgaa ttaactagca aatttaatga
    35461 tgataaagtt cgttttatac aagcggattt atctcaaaca attgatattg acaaaacatt
    35521 tggtgacatt aaatcattag actgtttaat atatgcaagt ggtcagtctt tatatggtgt
    35581 tttacaagat atgaaagacc atgatattga tgcatgttat cagttaaatg tcttgcaatt
    35641 aattcgatta tgtagatatt tcgttgatgt tttacgtcaa agtgccaatg gaagaattat
    35701 tgtaatttca tcaatttggg gtgagacagg agctagtatg gaaactattt attcggcgat
    35761 gaaaagtgca caattaggtt tcgttaaggc gcttagtcaa gagcttgcac taacatcagt
    35821 gacagtaaat gctatcgcac ctggatttgt agccggtaat atggcaagtg agtggcaaga
    35881 agatgaactt caagcaatga taactgaatt accacaacag cgattggttt taccgagtga
    35941 ggttgctcat acatgcgcct atttatatca ctcaaatgct agaagcgtta ctggaactat
    36001 acagaaagtt aatggtgctt ggtatattta aaatatagaa ctatttttat gagcaaatgt
    36061 ttttatgatt gatgttataa tatgaatatt acaatgaatc ataatttgtt aattaaacaa
    36121 ggggtgaggt tcaccatgac agttgcagag aaaaaagaat ggtacctaga atacgaaatt
    36181 gaaattaata gaccgggtct tttaggtgat gtatctagtt tattaggtat gttaggtata
    36241 agtattgtta caattaatgg tgttgatcaa ggtaaacgag gccttttaat taaaacagac
    36301 aatcttgaaa aagttgaacg ttttgagcaa atagctcgtg gtataaatga aattgaaata
    36361 acaaagctta aaaaaccaga attaagagac cgtcttgcag ttagacatgg tagatatatt
    36421 gagcaagatg caaaagataa gaaaaccttt cgatttgagc gtgaagattt aggcttgtta
    36481 gtagactttt tagctgaatt gttcaaagaa gaaggtcata agttgattgg cattagaggt
    36541 atgccacggg ttggtaaaac tgaatcaatt gttgcgggaa gtgtttgtgc acataagaga
    36601 tggttattta ttagttctac tttaataaaa caaactgtac gtagctctct aattaaaggg
    36661 gaatatgatg ccaatcatgt atacattatt gatggtgcag ttactgccag agaatctaat
    36721 ccaaaacatc aagagcttgt taacgaagtt atgacgttac catcaatcaa agtcgttgaa
    36781 catccagatt tatttgttga aacaagtact tgtacaatgg aagattttga ctatattatc
    36841 gaattgagag aaaatgaaaa tcaagaaata cattacgaag aaatgaagaa acagacagtc
    36901 caaagtaaga ataatttaga ttttggagat ccgtttggtg gtggttttgg tttcttcgag
    36961 taagtgtaag gaggctatga attgaaaacg gtcggtgaag cgctaaaagg tagacgtgaa
    37021 aggttaggaa tgactttaac agaattagag caacgtactg gaattaaacg tgaaatgcta
    37081 gtgcatattg aaaataatga attcgatcaa ctaccgaata aaaattacag cgaaggattt
    37141 attagaaaat atgcaagcgt agtaaatatt gaacctaacc aattaattca agctcatcaa
    37201 gatgaaattc catcgaacca agccgaatgg gacgaagtaa ttacagtttt caataataat
    37261 aaagacttag attataagag taaatcaaaa gagccaatac aattattagt aatcatgggt
    37321 attacagttt taataacttt attgttatgg atcatgttag ttttaatatt ttaacagaaa
    37381 taaattagtg agaaatgagg atgtataatg aatattccga accagattac ggtttttaga
    37441 gtagtgttaa taccagtttt tatattgttt gcgttagttg attttggatt tggcaatgtg
    37501 tcatttctag gaggatatga aataagaatt gagttattaa tcagtggttt tatttttata
    37561 ttggcttccc ttagcgattt tgttgatggt tatttagcta gaaaatggaa tttagttaca
    37621 aatatgggga aatttttgga tccattagcg gataaattat tagttgcaag tgctttaatt
    37681 gtacttgtgc aactaggact aacaaattct gtagtagcaa tcattattat tgccagagaa
    37741 tttgccgtaa ctggtttacg tttactacaa attgaacaag gatttgtaag tgcagctggt
    37801 caattaggta aaattaaaac agcagttact atggtagcaa ttacttggtt gttattaggt
    37861 gatccattgg caacattgat tggtttgtca ttaggacaaa ttttattata cattggcgtt
    37921 atttttacta tcttatctgg tattgaatac ttttataaag gtagagatgt ttttaaacaa
    37981 aaataaatat ttgtttatac tagatttcat tttcatatgg aatctagttt ttttaatccc
    38041 aattttagaa attagccacg caattgttta taatgatat
//
LOCUS       DAPDIM010000024        37275 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000024 DAPDIM010000000
VERSION     DAPDIM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 37275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37275
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.024"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(400..804)
                     /locus_tag="RFE25_001258"
     CDS             complement(400..804)
                     /locus_tag="RFE25_001258"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDU2816329.1"
                     /translation="MNTLNLDIVTPNGSVYNRDNVELVVMQTTAGEIGVMSGHIPTVA
                     ALKTGFVKVKFHDGTEYIAVSDGFVEVRKDKVSIIVQTAETAREIDVERAKLAKARAE
                     SHLENDDDNTDIHRAERALERANNRLRVAELK"
     gene            complement(824..2236)
                     /gene="atpD"
                     /locus_tag="RFE25_001259"
     CDS             complement(824..2236)
                     /gene="atpD"
                     /locus_tag="RFE25_001259"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017636767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDU2816330.1"
                     /translation="MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLT
                     LEVALQLGDDVVRTIAMDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDL
                     KEEISDSVRRDPIHRQAPAFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVG
                     KTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEP
                     PGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTTKGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTE
                     MGIYPAVDPLASTSRALEPSIVGQEHYEVARDVQSTLQKYRELQDIIAILGMDELSDE
                     DKQTVERARRIQFFLSQNFHVAEQFTGQKGSYVPVKTTVANFKDILDGKYDHIPEDAF
                     RLVGSMDDVIAKAKDMGVEV"
     gene            complement(2258..3124)
                     /locus_tag="RFE25_001260"
     CDS             complement(2258..3124)
                     /locus_tag="RFE25_001260"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500821.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDU2816331.1"
                     /translation="MASLKEIDTRIKSTKKMKQITKAMNMVSSSKLRRAEKNTKQFTP
                     YMDKMQDAITAVAGASSNTNHPMLRPRKITRSGYLVITSDKGLAGAYSANVLKKLITD
                     IEAKHQDSSEYSIVVLGQQGVDFLKNRGYDIEYSQVDVPDQPSFKSVQALANHAIDLY
                     SEEEIDELNIYYSHYVSVLENKPTSRQVLPLSQEDSSKGHGHLSSYEFEPDKESILSV
                     ILPQYVESLIYGTILDAKASEHATRMTAMKNATDNATELIDDLSLEYNRARQAEITQQ
                     ITEIVGGSAALE"
     gene            complement(3155..4663)
                     /locus_tag="RFE25_001261"
     CDS             complement(3155..4663)
                     /locus_tag="RFE25_001261"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDU2816332.1"
                     /translation="MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGL
                     NDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEE
                     LIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGAL
                     DYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNV
                     ISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     ESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPV
                     VDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE"
     gene            complement(4685..5224)
                     /locus_tag="RFE25_001262"
     CDS             complement(4685..5224)
                     /locus_tag="RFE25_001262"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDU2816333.1"
                     /translation="MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLK
                     MVDSNPTQTAEQRRELINGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGH
                     YNQDFATIESTYELSQEELDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVL
                     DGSVRNDLVQLQRKFRRVN"
     gene            complement(5224..5745)
                     /locus_tag="RFE25_001263"
     CDS             complement(5224..5745)
                     /locus_tag="RFE25_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDU2816334.1"
                     /translation="MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLK
                     DVMDKRERDINRDIDDAEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQE
                     QIIHEANVRANGMIETAQSEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQK
                     ALVDKYLKEAGDK"
     gene            complement(5943..6155)
                     /gene="atpE"
                     /locus_tag="RFE25_001264"
     CDS             complement(5943..6155)
                     /gene="atpE"
                     /locus_tag="RFE25_001264"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HDU2816335.1"
                     /translation="MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMG
                     IMFIGVGLVEALPIIGVVIAFMTFAG"
     gene            complement(6198..6926)
                     /gene="atpB"
                     /locus_tag="RFE25_001265"
     CDS             complement(6198..6926)
                     /gene="atpB"
                     /locus_tag="RFE25_001265"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDU2816336.1"
                     /translation="MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRN
                     LKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSI
                     VTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIIN
                     VFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFV
                     GTIQAYIFIMLSMVYMSHKVADEH"
     gene            complement(6947..7399)
                     /locus_tag="RFE25_001266"
     CDS             complement(6947..7399)
                     /locus_tag="RFE25_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDU2816337.1"
                     /translation="MNRIDTTNRLYYHLVCMSGTVFMIDISHTEAYKMSRFYNIFKQF
                     IQYYFYLIIILGGLYLYTHHAFILGLIIGVTGSAINTCIFECYLAKAKRPDTMHISTG
                     NMWRYLVAIIACMIWYLNKAHVSIIGIIIGLMISYVVVIIRPLLKVSK"
     gene            complement(7466..8593)
                     /gene="wecB"
                     /locus_tag="RFE25_001267"
     CDS             complement(7466..8593)
                     /gene="wecB"
                     /locus_tag="RFE25_001267"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDU2816338.1"
                     /translation="MKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREML
                     DSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQLEQVIQLEKPDMVLVHGDTMTTFA
                     GGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSE
                     GKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIF
                     KAVRHLIDEYTDLALVYPMHKNPKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSY
                     FILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGTNKQNVYQAAKELIDD
                     ERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF"
     gene            complement(8617..9246)
                     /gene="upp"
                     /locus_tag="RFE25_001268"
     CDS             complement(8617..9246)
                     /gene="upp"
                     /locus_tag="RFE25_001268"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017636774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDU2816339.1"
                     /translation="MSKVHVFDHPLIQHKLSYIRDVNTGTKEFRELVDEVGMLMAYEV
                     TRDLELQDVDIETPVTKMTAKRLAGKKLAIVPILRAGLGMTDGILSLVPAARVGHIGL
                     YRDPETLKAVEYFAKLPQDITERQIIVVDPMLATGASAIEAITSLKKRGAKNIRFMCL
                     IAAPEGVEKMHEAHPDVDIYIAALDEKLNDKAYITPGLGDAGDRLFGTK"
     gene            complement(9274..10512)
                     /locus_tag="RFE25_001269"
     CDS             complement(9274..10512)
                     /locus_tag="RFE25_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDU2816340.1"
                     /translation="MSYITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQG
                     SVLTNKYAEGYPGRRYYGGCEFVDVTESIAIDRAKALFGAEHVNVQPHSGSQANMAVY
                     LVALEMGDTVLGMNLSHGGHLTHGAPVNFSGKFYNFVEYGVDKDTERINYDEVRKLAL
                     EHKPKLIVAGASAYSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYAD
                     FVTTTTHKTLRGPRGGMILCKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALEN
                     NFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS
                     VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKDEE
                     KLQQAKERVAKLTAEYPLYQ"
     gene            complement(10539..11063)
                     /locus_tag="RFE25_001270"
     CDS             complement(10539..11063)
                     /locus_tag="RFE25_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HDU2816341.1"
                     /translation="MKDLTMLLDELKDMSFFNKGDICLIGCSTSEVIGEKIGTVGSME
                     VAETIFNALDVVSKETGVTFAFQGCEHINRAITIEKSQYNPLTMEEVSVVPDVHAGGS
                     LATYAFQHMKDPIVVEHITVPCGIDIGQTLIGMHIKHVCVPVRTSVKQVGQAIVTIAT
                     SRPKKIGGERAKYK"
     gene            complement(11170..11589)
                     /locus_tag="RFE25_001271"
     CDS             complement(11170..11589)
                     /locus_tag="RFE25_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDU2816342.1"
                     /translation="MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVS
                     NYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEY
                     VKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC"
     gene            complement(11586..12632)
                     /locus_tag="RFE25_001272"
     CDS             complement(11586..12632)
                     /locus_tag="RFE25_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDU2816343.1"
                     /translation="MDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGL
                     AANATDEEAVAKIYEAKGRPSDNPLIVHIHSKVQLKDFTYTLDPRVEKLMQAFWPGPI
                     SFILPLKPGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTT
                     FNHVYQDLNARIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSI
                     AHADYNDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAF
                     IPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRM
                     LKAAGNHIIKGCEL"
     gene            complement(12716..13552)
                     /gene="prmC"
                     /locus_tag="RFE25_001273"
     CDS             complement(12716..13552)
                     /gene="prmC"
                     /locus_tag="RFE25_001273"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDU2816344.1"
                     /translation="MVNYKEKLDEAIHLTQQKGFEQTRAEWLMLDVFQWTRTDFVVHM
                     HDDMPKAMIMKFDLALQRMLLGEPIQYIVGFASFYGRTFDVNSNCLIPRPETEEVMLH
                     FLQQLEDDATIVDIGTGSGVLAITLKCEKPDLNVIATDISLEAMNMARNNAEKHQSQI
                     QFLTGDALKPLIKEGIKLNGLISNPPYIDEKDMVTMSPTVTRFEPHQALFADNHGYAI
                     YESIIGDLPHVMEKGSPVVFEIGYNQGEALKSIILNKFPDKKIDIIKDINGHDRIVSF
                     KW"
     gene            complement(13539..14615)
                     /gene="prfA"
                     /locus_tag="RFE25_001274"
     CDS             complement(13539..14615)
                     /gene="prfA"
                     /locus_tag="RFE25_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDU2816345.1"
                     /translation="MFDQLDIVEERYEQLNELLSDPDVVNDSDKLRKYSKEQADLQKT
                     VDVYRNYKAKKEELADIEEMLSETDDKEEVEMLKEESNGIKAELPNLEEELKILLIPK
                     DPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAESQGFKTEIVEASESDHGGYKE
                     ISFSVSGNGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEVEDVEIEIRNE
                     DLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLY
                     DMKVQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHHIGLTLQKLGQIMEGHL
                     EEIIDALTLSEQTDKLKELNNGEL"
     gene            complement(14616..15215)
                     /locus_tag="RFE25_001275"
     CDS             complement(14616..15215)
                     /locus_tag="RFE25_001275"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDU2816346.1"
                     /translation="MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKP
                     AIDDRYHKEKVVSHNGNAIEAINISKASEIMTHNLTNVDVIGIDEVQFFDDEIVSIVE
                     KLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLIN
                     GKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL"
     gene            complement(15562..15816)
                     /locus_tag="RFE25_001276"
     CDS             complement(15562..15816)
                     /locus_tag="RFE25_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDU2816347.1"
                     /translation="MKQGIHPEYHQVIFLDTTTNFKFLSGSTKTSSEMMEWEDGKEYP
                     VIRLDISSDSHPFYTGRQKFAAADGRVERFNKKFGLKSNN"
     gene            complement(15934..17250)
                     /gene="rho"
                     /locus_tag="RFE25_001277"
     CDS             complement(15934..17250)
                     /gene="rho"
                     /locus_tag="RFE25_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDU2816348.1"
                     /translation="MPERERTSPQYESFHELYKNYTTKELTQKAKTLKLTNYSKLNKK
                     ELVLAIMEAQMEKDGNYYMEGILDDIQPDGYGFLRTVNYSKGEKDIYISASQIRRFEI
                     KRGDKVTGKVRKPKDNEKYYGLLQVDFVNDHNAEEVKKRPHFQALTPLYPDERIKLET
                     ETQNYSTRIMDLVTPIGLGQRGLIVAPPKAGKTSLLKEIANAISTNKPDAKLFILLVG
                     ERPEEVTDLERSVEAAEVVHSTFDEPPEHHVKVAELLLERAKRLVEIGEDVIILMDSI
                     TRLARAYNLVIPPSGRTLSGGLDPASLHKPKAFFGAARNIEAGGSLTILATALVDTGS
                     RMDDMIYEEFKGTGNMELHLDRKLSERRIFPAIDIGRSSTRKEELLISKSELDTLWQL
                     RNLFTDSTDFTERFIRKLKRSKNNEDFFKQLQKSAEESTKTGRPII"
     gene            complement(17497..18924)
                     /locus_tag="RFE25_001278"
     CDS             complement(17497..18924)
                     /locus_tag="RFE25_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDU2816349.1"
                     /translation="MRDYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADV
                     DKAVEAADDVYLEFRHTSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERV
                     HYQMGLNHFVAARDALDNYEFEERRGDDLVVKEAIGVSGLITPWNFPTNQTSLKLAAA
                     FAAGSPVVLKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRM
                     MSFTGSGPTGSKIMEKAAKDFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTG
                     QVCTAGTRVLVPNKIKDAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYI
                     NKGIEEGAELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYND
                     LDEAIQIANDTKYGLAGYVIGKDKETLHKVARSIEAGTVEINEAGRKPDLPFGGYKQS
                     GLGREWGDYGIEEFLEVKSIAGYFK"
     gene            complement(19162..19497)
                     /locus_tag="RFE25_001279"
     CDS             complement(19162..19497)
                     /locus_tag="RFE25_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2816350.1"
                     /translation="MEVCPYLEETFKILGRSWNGLIINYLSRCNDCSAHFSDMKRDLK
                     TITPRALSLKLSELAQWELVEKQIISTSPVQIIYVLTEKGKALAEALHPIEAWAQSYV
                     DLTDQRTAK"
     gene            complement(19586..20845)
                     /locus_tag="RFE25_001280"
     CDS             complement(19586..20845)
                     /locus_tag="RFE25_001280"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDU2816351.1"
                     /translation="MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLE
                     GLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGA
                     MLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIF
                     LDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKI
                     NGVKELHGSEYQVIPDRIEAGTYMCIAAACGENVILNNIVPKHVETLTAKFSELGVNV
                     DVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGPSFVTDTIYPERF
                     KHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYN
                     VKHIYRGYTDIVEHLKALGADIWTETV"
     gene            complement(21311..22171)
                     /locus_tag="RFE25_001281"
     CDS             complement(21311..22171)
                     /locus_tag="RFE25_001281"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002468309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HDU2816352.1"
                     /translation="MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAP
                     VILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPVAIHLDHGSSFEKCKEAIDAGFT
                     SVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE
                     CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKD
                     IQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKI
                     KEFGTSNRAK"
     gene            22389..22910
                     /locus_tag="RFE25_001282"
     CDS             22389..22910
                     /locus_tag="RFE25_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2529 domain-containing protein"
                     /protein_id="HDU2816353.1"
                     /translation="MSKILNTQLIGIFNRLEKQSLEIQMAAQCLIQAIGGEGYVYVKG
                     YDDLQFFESFILHSDERLKSSRKLDAIKDFKEIDSTDRVLLFAPFYNDQVALDIQKLI
                     DLDIDVVLISNKPKTDDFPDHLVHFIDLSTPRPIVYTEDYDKIVQPHAIALNYVYYDI
                     YTQMIEMTRDLEL"
     gene            complement(23019..24629)
                     /locus_tag="RFE25_001283"
     CDS             complement(23019..24629)
                     /locus_tag="RFE25_001283"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HDU2816354.1"
                     /translation="MTKFIFVTGGVVSSLGKGITASSLGRLLKDRGLNVTIQKFDPYL
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTAGKVYSHVLKKE
                     RRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFIEAIRQ
                     IRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMT
                     QDLKDKIALFCDINKESVIECRDADSLYEIPLQLSQQNMDDIVIKRLQLNAKYETQLD
                     EWKQLLDIVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFAKDIDIRWIDSSE
                     VTDENAAEYLADVDGILVPGGFGFRASEGKISAIKYARENNVPFFGICLGMQLATVEF
                     SRNVLGLEGAHSAELDPATPYPIIDLLPEQKDIEDLGGTLRLGLYPCSIKEGTLAQDV
                     YGKAEIEERHRHRYEFNNDYREQLEANGMVISGTSPDGRLVEMVEIPTNDFFIACQFH
                     PEFLSRPNRPHPIFKSFIEASLKYQQNK"
     gene            complement(24965..25495)
                     /locus_tag="RFE25_001284"
     CDS             complement(24965..25495)
                     /locus_tag="RFE25_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HDU2816355.1"
                     /translation="MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALG
                     DYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILD
                     ADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDE
                     LDEDEEVFEDEEDFND"
     gene            complement(25607..26467)
                     /locus_tag="RFE25_001285"
     CDS             complement(25607..26467)
                     /locus_tag="RFE25_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2816356.1"
                     /translation="MAKELCFEGITLKAFDEQYRSAINDFDLNERQQIYSSLPKEVID
                     DAINDVDRIANVAINDKNEVVGFFVLHRYYQHEGYDTPENVVYIRSLSINEKYQGFGY
                     GTKIMMSLPQYVQGVFPDFNHLYLVVDAENDNAWNLYERAGFMHTATKEEGPIGKERL
                     YYLDLDSKHVSSLKLEEESRSEVTNVHIINLMIDGQKVGFIALEQIGERMNIAAIEVD
                     KSYRFNGIGSSALRQLPTYLRKNYDNLNVITMILFGENNDFKPLCLNSNFVEIEQTDD
                     YVVFEKYLNY"
     gene            26892..27695
                     /gene="coaW"
                     /locus_tag="RFE25_001286"
     CDS             26892..27695
                     /gene="coaW"
                     /locus_tag="RFE25_001286"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II pantothenate kinase"
                     /protein_id="HDU2816357.1"
                     /translation="MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQI
                     EKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTS
                     LHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
                     KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTE
                     NIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLGK"
     gene            complement(27826..28497)
                     /locus_tag="RFE25_001287"
     CDS             complement(27826..28497)
                     /locus_tag="RFE25_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2750 domain-containing protein"
                     /protein_id="HDU2816358.1"
                     /translation="MSYKAYPFFRDILINECIYFASKNKKLVRLNYKSEAYVGVWTEE
                     SVAVSFLTSRDIPFDKVVKMDVDRFATYELDELFDEQDHIIMNQTMEEEGHLLNVVAV
                     TQEVMTELDKIRIKEFVQDVAKYDEVYGLTKKGSKQFILISENDSDEKKPHIMPVWSI
                     KNRALKVRDEDFEECDLITIEGSVFGEWLDELRDDHKAVAIDLKTGVVGTIVSAQKLS
                     NELTF"
     gene            complement(28896..30089)
                     /locus_tag="RFE25_001288"
     CDS             complement(28896..30089)
                     /locus_tag="RFE25_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDU2816359.1"
                     /translation="MTNNGNEPNLTLSDLYDKDVVYTSRPSYISNPWLKPDEHQSNFL
                     TGRELLIANQLPVIVHEASATDKLHQLFQVIGKEVPNSIFTFNNQQSYENLIKQLAHK
                     ENKKIYFQYIHDETILNQQYYALDKTLFVALNNKARIPEWTNGKFLPKRKVVKIEQFE
                     NEIKNWEFPLVIKPGDDLPTAGGYGVMICYHDADLQKAITRIKEATAETNSLIIEQKI
                     EEKANYCVQFAYSESLGIQYLGAATQLTDKYGFYNGNENTTNVPEHVIEAGRQIMENG
                     VNQGFFGVAGFDLLVDEDDNVYAIDLNFRQNGSTSMLLLANELNSGYQKFYSYHSKGD
                     NTHFFNTILKYVKEGSLYPLSYYDGDWYGEDKVKSRFGCIWHGDSKETVLENERAFLA
                     ELEHY"
     gene            complement(30089..31273)
                     /locus_tag="RFE25_001289"
     CDS             complement(30089..31273)
                     /locus_tag="RFE25_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDU2816360.1"
                     /translation="MSEKQQILDYIETNKYSYIEISHRIHERPELGNEEIFASRTLID
                     RLKEHDFEIETEIAGHATGFIATYDSGLDGPAIGFLAEYDALPGLGHACGHNIIGTAS
                     VLGAIGLKQVIDQIGGKVVVLGCPAEEGGENGSAKASYVKAGVIDQIDIALMIHPGNE
                     TYKTIDTLAVDVLDVKFYGKSAHASENADEALNALDAMISYFNGVAQLRQHIKKDQRV
                     HGVILDGGKAANIIPDYTHARFYTRAMTRKELDILTEKVNQIARGAAIQTGCDYEFGP
                     IQNGVNEFIKTPKLDDLFAKYAEEVGEAVIDDDFGYGSTDTGNVSHVVPTIHPHIKIG
                     SRNLVGHTHRFREAAASVHGDEALIKGAKIMALMGLELITNQDVYQDIIEEHAHLKGN
                     GK"
     gene            31584..32054
                     /locus_tag="RFE25_001290"
     CDS             31584..32054
                     /locus_tag="RFE25_001290"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDU2816361.1"
                     /translation="MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQ
                     PNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIV
                     EATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK"
     gene            complement(32206..32556)
                     /locus_tag="RFE25_001291"
     CDS             complement(32206..32556)
                     /locus_tag="RFE25_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816362.1"
                     /translation="MNILRYLLGIGFSVIGVLHFTRERQFRNIIPKCLPLRKTAVLVT
                     GIFEILFGLALLIKRPSQCLKNTINLFLLAVFPANIYMAVKKLPLGDKQLPTWQLYLR
                     LPMQFVLMGLIKKL"
     gene            complement(32570..33871)
                     /locus_tag="RFE25_001292"
     CDS             complement(32570..33871)
                     /locus_tag="RFE25_001292"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDU2816363.1"
                     /translation="MRMIDIIEKKRDGHTLTTEEINFFIDGYVKGDIPDYQASSLAMA
                     IYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVDKHSTGGVGDTTTLVLAPLVAAV
                     DVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPA
                     DKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALA
                     HAMVRIGNNVGRNTMAIISDMNQPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLG
                     SQMVVLANKAETLEEARALLIEAINSGAALEKFKTFIKNQGGDETVIDHPERLPQAQY
                     QIEYKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGE
                     SLLTIHSNRQDVDDVVKKLDSSITIADHVVSPTLIHKIITE"
     gene            complement(34150..34812)
                     /gene="deoC"
                     /locus_tag="RFE25_001293"
     CDS             complement(34150..34812)
                     /gene="deoC"
                     /locus_tag="RFE25_001293"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDU2816364.1"
                     /translation="MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYHFKSVCVNPTHVK
                     YAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRF
                     DDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKVAGADFVKTSTGFAGGG
                     ATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADS
                     DY"
     gene            35126..35836
                     /gene="deoD"
                     /locus_tag="RFE25_001294"
     CDS             35126..35836
                     /gene="deoD"
                     /locus_tag="RFE25_001294"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDU2816365.1"
                     /translation="MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFND
                     VRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVN
                     LYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSD
                     TFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPE
                     ERQNSFTQMMEIALEIAE"
     gene            complement(35957..36400)
                     /locus_tag="RFE25_001295"
     CDS             complement(35957..36400)
                     /locus_tag="RFE25_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDU2816366.1"
                     /translation="MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKF
                     EELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDF
                     TNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS"
     gene            complement(36600..37013)
                     /locus_tag="RFE25_001296"
     CDS             complement(36600..37013)
                     /locus_tag="RFE25_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase DCC family
                     protein"
                     /protein_id="HDU2816367.1"
                     /translation="MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFK
                     QHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRM
                     FANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD"
BASE COUNT        11336 a         7314 c         5365 g        13260 t
ORIGIN      
        1 ataatttcaa aaaatgaaat gtcgactgta gatagtggtg aaggaaattt tgattttagc
       61 aatctattag tgattgtaaa aaagtaaaac tattcttggg agtcggacat aaatcaatgt
      121 ctagactcta tagtgttgta tttggcagta gttgacgggg ccccaacata aagaaatact
      181 ttttctttaa aaattagtat ttcttataca tgagttttac tcatgtattc ctatttttaa
      241 atacacatta gctgtgttta atgataaaga accactacat cataaatctt taatggttct
      301 ttatcaattc cttcccccct ctcatgtttt gtatctttaa atcaatataa ttcaaaaaag
      361 ggtcgaagat atgaaatcac atcttcgacc ctttatttac tattttaatt cagccacacg
      421 caaacggtta tttgctctct ctaaagctct ttcggctcta tgaatatcag tattgtcgtc
      481 atcattttcc aagtgagact ctgctcttgc tttggctaat ttagctcttt caacatcaat
      541 ttctcttgca gtttctgcag tctgaacaat gattgaaact ttatcttttc taacttcaac
      601 aaagccatcg cttacagcaa tatattcagt tccatcgtga aatttcactt ttacaaagcc
      661 tgtttttaaa gcagctacag ttggaatatg tccactcatg acacctatct caccagctgt
      721 tgtttgcata acaacgagtt caacattatc acgattgtaa acagaaccat taggagtgac
      781 aatatctagg tttaatgtat tcattatcca ttcctcctaa ttgttatact tcaacaccca
      841 tatctttagc ttttgcaata acatcatcca tgctaccaac taaacggaat gcatcttctg
      901 gaatatggtc atatttacca tctaagatat ctttaaagtt tgcaactgtt gtcttaacag
      961 gtacataaga acctttttga ccagtaaatt gttccgctac gtggaagttt tgagataaga
     1021 agaattgaat tctacgtgcg cgttcaactg tttgtttatc ttcatcagat aattcgtcca
     1081 tacctaagat agcaatgata tcttgcaatt cacggtattt ttgaagtgtt gattgtacat
     1141 cacgagctac ttcataatgt tcttgaccta caattgatgg ttccaatgct cttgatgtag
     1201 acgctaatgg atccacggct ggataaatac ccatttcagt taatttacgt tctaagttag
     1261 tagttgcatc taaatgggca aacgctgtcg caggcgctgg gtcagtatag tcatcggcag
     1321 gtacgaatac cgcttgaata gaagtaactg atccttttgt tgtagacgta atacgttctt
     1381 gtaattgtcc catttcagta gcaagtgttg gttggtaacc tactgcagaa ggcatacgac
     1441 ctaataatgc agatacctca gaaccagctt gtgtaaatct gaaaatgtta tcgatgaata
     1501 ataatacgtc ttgaccttgt tcgtcacgga aatattcagc cattgttaaa ccagataatg
     1561 caacacgcat acgtgcacca ggtggctcat tcatttgccc gaataccatg gctgttttct
     1621 taattacacc actgtcactc atttcgaagt ataaatcgtt accttcacga gtacgttcac
     1681 ctacaccggc gaatacagaa ataccaccgt gctcttgagc gatgttgtta attaattctt
     1741 ggattaatac tgttttacct acaccggcac caccgaacaa tccgatttta ccacctttaa
     1801 tataaggtgc tagtaaatct actactttaa tacctgtttc taaaatttga acttctgttg
     1861 aaagttcatc gaatgctggt gcttgacgat ggataggatc gcggcgaaca gaatcactaa
     1921 tttcttcttt aaggtcaatt gtttcaccta gtacattaaa tacacgacct aatgtttcgt
     1981 caccaacagg tacactaatt tctttgcctg tatcttttac atccatgcct ctttggacac
     2041 catcagttga atccatcgca attgtacgaa caacgtcgtc acctaattgc agcgcaactt
     2101 ctaatgttag ttgtattgta ccttcttctt taggcacatc aataaccaag gcgttattaa
     2161 ttttaggaac ttcgttatgt tcaaatcgaa catcaattac aggacccata acttgagtta
     2221 cacggccaat tcccatgcta ttttcctcct ttaaatatta ttcaagcgct gcggaaccac
     2281 caacaatttc agtaatttgt tgcgtaattt ctgcttgtct cgctctgtta tattctaatg
     2341 ataagtcatc aataagttca gttgcattat cagtggcatt tttcatcgca gtcatacgtg
     2401 ttgcatgctc acttgctttt gcgtctaata ttgttccgta aatcaaactc tcaacatatt
     2461 gaggcaagat tacacttaag atagattctt tatctggctc aaattcataa gaagacaaat
     2521 gaccatgccc cttactagaa tcctcttgag ataatggtaa tacttgtcta gatgtaggct
     2581 tgttttcaag aacgctgaca taatgactat agtatatatt taattcatca atttcttctt
     2641 cactgtataa gtctatagca tggttagcta gtgcttgaac agatttgaaa gaaggttgat
     2701 caggtacgtc tacttgagaa tactcaatgt cataacctct attttttagg aaatcaacac
     2761 cttgttgccc taaaactaca atactgtatt cgctactatc ttgatgtttc gcttcaatat
     2821 cagtaatcaa ttttttaagc acgtttgcac tatatgcacc tgctaaacct ttatcactcg
     2881 tgataactaa atatccactt ctagtaattt tacgaggtct tagcattgga tggtttgtat
     2941 tgctacttgc ccctgcaact gcagtaattg catcttgcat tttatccata tatggtgtga
     3001 attgttttgt atttttttca gctctacgaa gttttgaact tgataccatg ttcatcgctt
     3061 tcgtaatctg cttcattttt ttggttgatt ttattcgagt atctatttct ttaagagaag
     3121 ccactatctc accaccttat actaaacttg tttattattc agatttgcta aagctttttt
     3181 tgaattcgtt aattgctgtg tcaaacttct cagcatctgg taagccacca gtttctctga
     3241 tttcatttaa cagttcagta gcatttgatt ctgcccagtg gtttaactcg tcttcaaaac
     3301 gtgtgatatc tacaactgga atatcatcta aatatccttt tgttaatgca taaataatca
     3361 acacttggtg ttcgactggt aatggtttgt tttgatcttg ttttaagact tcaacggtac
     3421 gtttaccacg ttctaattta cttgcagtaa attcatcaag gtctgaaccg aattgtgcaa
     3481 atgattcaag ttctctgtat gacgctaagt caagacgtaa cgtaccagca actttcttca
     3541 ttgctttaat ttgtgcagat ccaccaacac gagatacaga ttgtccggca ttaatcgctg
     3601 gtcttacacc tgagaagaat aaatcagatt gtaagaagat ttgtccatct gtaattgaaa
     3661 taacgtttgt tggtacataa gctgaaatat caccagcttg tgtttcgata attggtaatg
     3721 cagtaattga accgccacct aagtcatcgt ttaattttgc tgctctttct aataatctac
     3781 tatgtaagta gaatacgtca cctgggtatg cttcacgacc tggaggtcta cgtaataata
     3841 atgataactc acgataagct gctgcttgtt tagttaaatc atcataaacg attaaaacat
     3901 gtttaccgtt aaacatgaat tcttcaccca ttgttacacc tgaatatggt gcaatatata
     3961 ataatggaga aggttcagaa gctgatgctg ctacaacaat agtgtagtct aaagcgcctg
     4021 cttgtcttaa cttttcaaca tttgctctta ctgttgaatc tttttgacca atagcaacat
     4081 agatacaaat cgtaccttga tctttttggt tcaaaattgt gtcaattgca attgttgttt
     4141 tacctgtttg acggtcacca atgattaact cacgttgacc tctaccaatt ggtactaaag
     4201 catcaattgc tttgatacct gtttgtaatg gctcatctac tgatttacga tccattacac
     4261 cagtagcttt tttctctact ggacgtgttt tagttgtgtt aatcggtcct tgtccatcaa
     4321 taggttgtcc taatggatta acaactcttc cgattagttc ttcacctact ggtacttcca
     4381 tgatacgacc agtacgttta acttcgtcac cttcagtaat acctgtatat ggtcctaaaa
     4441 taaccacacc cacgtttgac tcttcaaggt tttgggctaa accaagtacg ccgttatgga
     4501 attctactag ctcaccagcc ataacgtcat ttaatccgtg aattaatgca ataccatcac
     4561 caatttgtaa tacagtacct acatcagtta cggacatttc tgactcataa ttttcaattt
     4621 gtgagcgaag taatgcactg atttcttcag cttttatggc catctatgtc actcctcttt
     4681 ataattaatt aactcttcta aattttcttt gtaattggac aagatcattt ctaacactac
     4741 catctaatac agttgtgccg actttaactc taaatccacc aattaaatct ggattaattt
     4801 ttgtatctac aataacttta gataacttcg tttgttgagt tactagtttg acaatcttat
     4861 ctaactcttc ttgactcaat tcatatgttg actcaattgt tgcaaaatct tgattgtagt
     4921 gtccgttata taagctttgg aacgccttga atacgtcagc tattaatgag atatgtctat
     4981 tatctgctaa cacgtacatc atatttttaa tgtatggatt aatgtcagta aatacaccat
     5041 taatcaactc acgacgttgt tctgctgttt gagttggatt actgtcaacc attttcaatt
     5101 gctcaatttt atcttttact gcttcattta taactgttaa ttcttcatta atagtctcta
     5161 aattatttgt atctaatgac acgtcaaata atgctttagc atacttgtta gctactttta
     5221 ccattattta tcgcctgcct cttttagata cttgtcaacc aatgcttttt ggtcttgttc
     5281 agaaatttct tttctaagaa ctttagaagc aattaacact gatagttcag atacttgatt
     5341 attaatatct gcaatggcac gttctttttg gctattgatt tcactttgtg ctgtttcaat
     5401 cataccgttt gcacgtacgt ttgcttcatg aataatttgt tcttgctgtt gacgtgcttg
     5461 aaccttagca tcttctaaaa tcttttgaac ttcttcttgt gtttctttaa gtttttgttt
     5521 attttcttct tcaagtttct gtgcatttaa cttagcttgt tctgcgtcat cgatatctct
     5581 gttaatatct ctttcacgtt tatccattac atctttcaat ggaccccatg cgaacttttt
     5641 aagtaacgca agtaacacga tgaaagttag gacctgtaca atcacagtac cccactcaac
     5701 gcctccagct gcaccaagaa cgaataagtt agctgtttca gtcacgggtt catgacactc
     5761 ctttcattaa aataatcgct agtgttatat agaaaaaaac gacgaggtta ggacctactg
     5821 aatttatgcg ataggcatgg tgcattcata tctcaactat ttaataaagt tcaaagatat
     5881 tactatatat gcatcatgaa ttatgtccta tgcgctttgt cccgacctct tttatctgtt
     5941 aattatccag caaatgtcat gaatgcaatt actacaccga tgataggtaa tgcctcaact
     6001 aaacctacac caatgaacat gatacccatt aattgaccac gtgcttctgg ttgacgtgct
     6061 acaccttcaa ctgttcttga aacgattaaa ccgttaccga tacctgctcc taatgctgat
     6121 aaaccaattg cgattgctgc tgcgattaaa ttcataattt aatttcctcc tgtgattgta
     6181 tataattatt gaaattttta gtgttcatct gccactttat gtgacatata aaccatcgaa
     6241 agcataataa agatatatgc ttggattgtt cctacaaata ttgaaaatgc ttgccaaaca
     6301 attaatcctg ggatactaat aatccaaccc catgctggtt cgttaaagaa taagccagca
     6361 agtaatgtta atagtatctc acctgcaaat atgttaccgt acaaacgcag accaagcgtt
     6421 aatgttgaag tgaactcttc aaaaacatta ataattgcca atggccaaaa cggctgtaca
     6481 taacctttaa gatattgttt cgtaccacgc attttaattc cataaaagtg agttaacagt
     6541 attatcgttg tagacaacgt taaagtcact gttgcatcag ctgtcggtga tttccaccac
     6601 aatgtgtgat ctttcgttac tatagaaaac ggaagaccta acatattagc tataaaaatg
     6661 tacagaatca gcgttactgc taagaagtgg aattgaccac cttttttcca agccatgtta
     6721 ccttcaatga ttcccctcac gaaatcaaaa atccattcaa cgaaattttg tttgccagtt
     6781 ggtctttttt tcaaattacg cgtacaaatg atagcaagta gaaaaacaag aaacgccgta
     6841 acaagtatca tcaatatact tgataaattg aaaacgatat caaaaccgaa taaattccaa
     6901 ctcacgagcg gggatttgtg atccataatc tcacctcttt cttaatttat ttgctcacct
     6961 ttagtaaagg acgtatgata actacaacat atgaaatcat taaaccaata attataccga
     7021 tgatacttac atgcgcttta ttaaggtacc aaatcataca ggcaataatt gcaactaagt
     7081 atcgccacat atttccagtt gaaatatgca tagtgtctgg tcttttagct ttagctaaat
     7141 agcattcaaa aatacatgtg ttgattgcag aaccagtaac accaatgatt aatcctaaga
     7201 taaatgcatg gtgtgtataa aggtataatc ctcccaatat tattattaga taaaaataat
     7261 attgaatgaa ctgtttaaaa atgttgtaga aacgactcat tttatatgcc tccgtgtgac
     7321 tgatatcaat catgaaaacc gttccactca tacaaactaa atgataatat aggcgatttg
     7381 tggtgtcaat tctattcaaa ttgttgtaaa aaaaaagcat agttagacac aatttagaca
     7441 caattagaca aaaagtctat tttcctcaga aatcgcttgg tttttcagtg attaaattca
     7501 aataatactt aatatgatta actattcttt ctgaagcaaa tccatcaccg taaggattag
     7561 atgcttcaga catttgatga tataatctct catcatcgat taattctttt gcagcttgat
     7621 acacattttg cttatttgtt ccaatgactt ttaatgtgcc agcttcaaca ccttcaggac
     7681 gttctgtaac gcttcgcaaa actaaaactg gcttattaaa tgatggcgct tcttcctgaa
     7741 ttccacctga atctgtcaaa ataaaataag attttttagc aaaattatgg aaatctacta
     7801 cgtccaaagg ttcaatcaat tcaattctgt catgactacc taaaatcttt tgagccacct
     7861 ctcgaacttt cgggttttta tgcattggat ataccagtgc taaatcagta tactcatcta
     7921 ttaagtgtct aaccgcttta aatatatttt ccatgggttt cccgatattt tctcgtcggt
     7981 gtgctgtcat aagaatgaat tttttgtcat ggtatttatc catgatgtta gatttataat
     8041 tgtcatcaac tgtatatttc atagcatcaa tcgcagtatt accagtgaca acaacacttt
     8101 ctgaatattt cccttcactt aacaaatgcg atgcagcatt tttagtaggt gcaaaatgta
     8161 agtcagctaa tacaccaact aattgtctat tcacctcttc tggaaaaggt gaatatttat
     8221 cataacttct aagccctgct tcaacgtgtc caatcggcac ttggttataa aatgccgcta
     8281 aaccacctgc aaatgtcgtc atcgtatcac catgtacaag taccatgtct ggtttttcta
     8341 attgaatcac ttgttctaat tgagtgattg atttagaagt tatctcagaa agtgtctgtc
     8401 ctgatttcat aatattcaaa tcgtattttg gtttgatttc aaaggtactt aatactgaat
     8461 caagcatttc tctatgctgt gctgtaacaa caacaattgg ctcgagcatt ttttcttgtt
     8521 ccaaagcttt aactaaagga gccatcttta tggcttcggg tcttgttcca aatatggtca
     8581 taatcttttt catcaaacta cttatctccg attcttctat ttagtaccaa acaatctatc
     8641 tccagcgtcg cctaaccctg gtgtgatata tgctttatca tttagctttt catcaagtgc
     8701 agcaatataa atatctacat ccggatgtgc ttcatgcatc ttttctacgc cttctggtgc
     8761 tgcaattaaa cacatgaagc gaatattttt agcgccacgt ttcttcaatg aagtaatagc
     8821 ttcaattgct gatgcgcctg ttgctaacat aggatcaaca acaatgattt gtctttcagt
     8881 aatatcttga ggtaacttag caaaatactc tacagccttt aatgtttcgg gatctcgata
     8941 taaaccgata tgtccaactc tggctgcagg tactaaactt aaaataccat cagtcatacc
     9001 taaaccagct cttaaaattg gaacgatagc taatttttta ccagctaatc gtttagccgt
     9061 cattttagtt acaggcgttt caatatcaac atcctgaagc tctaagtctc tagttacttc
     9121 atatgccatc aacataccaa cttcgtctac aagttctcta aattctttag tacctgtatt
     9181 tacatctcta atatagctta gtttgtgttg aattaatgga tgatcgaaaa cgtgtacttt
     9241 actcataaaa attactccta tctttgtgta tgtttattga tatagaggat attcagctgt
     9301 taatttcgca acgcgttctt tagcttgttg taatttttct tcatctttac tatttttcaa
     9361 tgctaaactg atgatttttg caacttcctc aaaagctttt tcatcaaatc cacgcgttgt
     9421 tgcagcaggt gtacctaaac gtataccact cgttacaaaa ggtttttctt gatcgaacgg
     9481 aatggtattt ttgttacatg tgataccaac tgaatctaaa gtctcttcag cttctttacc
     9541 agtaagtcct atagaccctt ttacatcaac agctactaag tgattatctg taccgccaga
     9601 aacaattcta aatccttcat taattaatgc ttctgcaaga acttttgcgt ttttaaccac
     9661 ttgttgttga tacgttttga aattattttc taacgcttct ccaaaagcaa ctgcttttgc
     9721 tgcaataaca tgctcaagag gtccaccttg aataccaggg aaaattgttt tatctatgtc
     9781 ttttttatat tcttccttac ataaaatcat accaccacgt ggtccgcgta atgttttgtg
     9841 tgttgtagtt gttacaaaat cagcatattc tactggattt ggatgtaaac ctgccgctac
     9901 taatcctgca atatgtgcca tgtctaccat taacttagcg tttacttcat ctgcgatttc
     9961 tttaaacttt ttgaagtcaa ttgttcttga atatgctgat gctcctgcca caataagctt
    10021 aggcttatgc tctaacgcta atttacgaac ttcatcataa ttgattcgtt ctgtgtcttt
    10081 atctactcca tattcaacga aattgtagaa tttaccacta aaattaacag gcgctccatg
    10141 tgtcaagtga ccaccatgac tcaaattcat acctaaaact gtgtcgccca tttctaatgc
    10201 aactaagtaa acagccatgt tcgcttgtga acctgaatgt ggttgaacat tgacatgttc
    10261 agctccaaac aatgctttag cacgatcaat tgcgatgctt tcagtaacat ctacaaactc
    10321 acatccacca taatatcggc gtcctggata gccttcagca tacttattag tcaacactga
    10381 accttgtgct tccataaccg cttccgatac aaaattttcc gatgcgatta actctatgtt
    10441 gctattttgt ctctgaaatt ctctctcgat tgcttctgcg ataactttat cttgcttggt
    10501 gatataagac ataaaatctc cccttctttc aaaaaaactt atttgtattt agcacgttcg
    10561 ccaccaatct ttttcggcct agatgtggca atagttacaa ttgcctgtcc tacttgcttt
    10621 actgaggtcc ttacaggtac acatacatgt ttaatatgca tgcctattaa tgtttgacca
    10681 atatcaattc cacaaggaac agtaatatgt tcgaccacga tcggatcctt catatgctga
    10741 aaagcgtatg ttgccaaact ccctccagca tgtacatctg gaacgacgga aacttcttcc
    10801 attgttaatg gattatactg agatttttct attgttatcg ctctgttgat atgttcacat
    10861 ccttgaaaag caaaagtaac gcctgtctct ttactcacaa catctaatgc attaaaaata
    10921 gtttctgcaa cttccatcga accgacagtc cctatttttt cgccaatgac ttccgatgtt
    10981 gaacatccaa ttaaacatat atctccttta ttaaaaaagg acatatcttt taattcgtct
    11041 aataacattg tcaaatcttt cataaaagcc cacccttcct aaaaataaaa aaggaatata
    11101 gcaaagtgct acactcctct attataactt atttaactgt taacatatac taattataca
    11161 gaattcctac tagcaaataa tatcttttaa ttttaaaatt aaacttacaa gttcttcata
    11221 ggtatgtaca tacatttctt ttgttccacc gtatggatct ataacttctc ctgcttcttt
    11281 tacatattca tgcaatgtga aaacatgatt ttgcaaacca aagtgtgcct ctattaattc
    11341 tttgtgcgaa tacgacatcg tcaaaataat atctgctttc aaatctgctt cagtaaattg
    11401 ttgcgataag gtcgtttcag ctaaatgatg ttcttcaact aagtcttcaa cataattcga
    11461 aacaccttga ttgttcacag cgaatatacc tcttgattca aattgatgat ttggcataac
    11521 ctcttttgca atactttccg ctaatgggct acgacatgtg ttacctgtac aaacgaataa
    11581 aatcttcata gttcacatcc tttaataatg tgattacctg cagcttttaa catgcgattc
    11641 ataattgctt ctgtattatc attcagctca aagccgtata tatacgccgc tgaaatattt
    11701 tcattttcat caagtgaatg taacacatca taaagattat gacttgcttg tttaacatca
    11761 ttgtcatcct gacataattg aatgaattgc gcttcacttg gtataaacgc caccttatta
    11821 ctcggcacaa taaaagctat agaagaccaa tctttaccgt catttccaat tttgctctca
    11881 atatctgtaa taattgtaag tggtgtattg ggtgagtaat gcttatactt catacctggt
    11941 gcaattggct gttcagtatc attataatca gcatgggcga tactattcgg aagtatttct
    12001 gtaatcattg ctgctgttat agaaccaggt cttgcaattt tataaggaaa agatgtgcaa
    12061 tctaaaaccg tactttctaa tccttcttca ctttgttcag cttgaacaat accatctata
    12121 cgggcattca aatcttgata tacatgattg aaagttgttg gtgaaggtct accacttaaa
    12181 ttagcacttg gagcagctag aggttcattt atgatttgta ataattgtct acctacagaa
    12241 tggcttggca ttctaacagc aactgatgat aaacctccag aaacttttcg acatagatag
    12301 cctggcttta gcggcaatat aaacgaaata gggcccggcc agaatgcctg cattaacttt
    12361 tctacgcgtg gatccaaagt atatgtaaaa tcttttaatt gaactttact gtgtatatga
    12421 acaataagcg gattgtcaga tggacggcct ttagcttcat atattttagc tacagcttct
    12481 tcatctgtcg catttgctgc aagtccataa actgtttcag ttggtaaacc tattaaacca
    12541 ccgtttaaaa caatgtcttt tatttcatta attttaggat attgctgtaa atcttcatta
    12601 tattctctaa catcccaaat tttagtatcc aacttaatca cgcctttctt atttatcata
    12661 atataaagca aaaagctatg cacttaacta atcatagcaa aggcataact tctaattacc
    12721 atttaaatga gacgattcga tcgtggccat ttatatcttt aataatgtcg atttttttgt
    12781 caggaaattt atttaaaatt attgatttaa gtgcctcacc ttgattgtaa ccaatttcaa
    12841 aaacaactgg gctgcctttt tccataacgt gaggtaaatc tccaatgatt gattcataaa
    12901 tagcatatcc atggttatct gcaaacaatg cctgatgtgg ttcgaatctc gtaaccgttg
    12961 gagacatcgt aaccatatct ttttcatcta tatatggtgg attagatatc aagccgttca
    13021 acttgatacc ttctttaatt aagggcttta atgcatcccc tgttaaaaat tgtatttgtg
    13081 attgatgctt ctcagcatta ttacgagcca tattcattgc ttcaagtgaa atatcagtag
    13141 caataacatt taaatccggc ttttcacatt tcaaagtaat tgcaagtaca ccactacccg
    13201 ttccgatatc tacgattgtt gcatcatctt ctaactgttg taagaaatgc aacattactt
    13261 cttcagtttc aggtcttggt atcaaacaat ttgagtttac atcaaacgtt ctaccataaa
    13321 atgaggcaaa gccaactata tactgtatag gctctcctaa taacatacgt tgtaatgcta
    13381 agtcgaactt cataatcatc gctttcggca tatcatcatg catgtgaact acaaagtccg
    13441 tacgcgtcca ttgaaataca tctaacatta accattcagc tcgtgtttgt tcaaaccctt
    13501 tttgttgtgt taaatgaatt gcttcatcta acttttcttt ataattcacc attattaagt
    13561 tctttcaatt tatctgtctg ctctgataaa gtcagtgcat ctataatttc ttctaaatgg
    13621 ccttccataa tttgccctaa tttttgaagc gttagaccta tatgatggtc tgttacacgg
    13681 ctttgtggat aattataagt tcgaatacgt tctgaacgat caccagtacc gactgctgat
    13741 ttacgttgtg acgcatactt ttgttgttct tcttgaactt tcatatcgta taaacgtgct
    13801 tttaacactt tcattgcttt ttcacggttt tgaatttgag acttctcaga agatgttgca
    13861 atgacaccag ttggtaaatg ggtaatacgt actgcagagt cagttgtgtt tacgtgctga
    13921 ccacctgcac cacttgaacg atacgtgtcg atttttaaat cttcatttct aatttcaatt
    13981 tctacatctt caacttctgg taaaactgcc actgtagctg ttgaagtatg aatacgtcca
    14041 cctgattctg tttcaggcac acgttgaacg cggtgcgcac cattttcaaa tttcaattta
    14101 ctatacgcgc cattaccaga aactgagaaa ctaatttctt tgtaaccacc atggtcactt
    14161 tcagacgctt ctactatttc agttttgaat ccttgtgatt cagcatactt tgaatacata
    14221 cgcattaaat caccagcaaa aatcgcagcc tcatcaccac ctgctgctgc tcttatttct
    14281 acaataacgt ctttgtcatc attaggatct ttaggaatca ataatatttt aagctcttct
    14341 tcaagatttg gaagttcagc tttaatacca ttactctcct cttttaacat ttctacttct
    14401 tctttatcat cagtctcact taacatttct tcaatatcag ctaattcttc ttttttagct
    14461 ttatagttac gataaacatc tacagttttt tgtaaatcag cttgctcttt agaatattta
    14521 cgtaatttat ctgaatcatt tacaacatct gggtcactta acagttcatt taactgttcg
    14581 tatctttctt ctacaatatc taattgatca aacacttata attcctcctt attattatca
    14641 ctaggtgcta cgatatggtg cgcgcgacaa cgtggctcat aactttcatt ggcacctact
    14701 aagataatcg gatcatcgat tttagctggt ttaccattta ttaatcgttg cgttctacta
    14761 gatgaagaac cacaaacagc acaaactgct tgaagtttcg ttacttgttc actgacagcc
    14821 atcaatttag gcattggttc gaacggttcg cccctaaaat ccatatctaa tccagcaaca
    14881 ataacacggt gtccatctgc tgatagtttt tctactatac ttacaatttc atcgtcaaaa
    14941 aattgcactt cgtctattcc tataacatca acattagtta agttgtgcgt cataatttca
    15001 cttgctttag aaatattaat cgcttcaatg gcattaccat tatgagagac cactttttct
    15061 ttatgatatc gatcatcaat cgccggttta aatacaacga ctttttgttt agcgtatata
    15121 ccccttctta gacgtcttat tagttcttcg gatttaccgc taaacatact acctgtaata
    15181 cattctatcc aaccggaatg gtaagtttca tacattgaga gttccacctt tttcaaaaaa
    15241 taatcgcttt attatatcat atttcaaata ttcataaatg tctttttcat aattatatcg
    15301 atattgtaca tgaacaatta ttttataaat ttgtcttgca tatttatata cagctattct
    15361 aatttgttgc ttcttattcg tgcggtgttt ctactcaata caaactttaa taaaggggga
    15421 aatttatcat tatgtattaa caacatggta ttgagtcact tctttgaaca cagtcgtaag
    15481 tatataccct tactacgctt ataaataaaa aagctgtcta caattccatt ataggatgca
    15541 gacagcttaa cgattactat attagttgtt tgatttaaga ccaaactttt tgttgaaacg
    15601 ttccacacgt ccatccgcag cagcgaattt ttgacgtcca gtgtagaatg gatgtgaatc
    15661 agatgaaata tctaaacgaa taactgggta ttcttttcca tcttcccact ccatcatttc
    15721 tgaagatgtt tttgtagaac cgcttaagaa tttgaagttt gtagtagtat ctaaaaagat
    15781 tacttggtga tactcaggat gaattccttg tttcattatt ttcagctcct ttgccctgaa
    15841 ccatctggaa cagagttatt tgtgagtttt tacccaatac tgtgtaatta taaaggtaat
    15901 taattcaaaa cgcaagcccc tatataatgt ttattaaatt ataggtcgac ccgttttagt
    15961 actttcttct gcagactttt gtagctgctt gaagaaatct tcattattct tagacctttt
    16021 aagtttgcga ataaatcttt cagtaaagtc agttgagtca gtgaatagat ttcttaattg
    16081 ccataatgtg tctaattcag atttacttat taacaattct tctttacgcg ttgaacttct
    16141 gccaatatca attgcaggga agatacgacg ttcagacaat ttacgatcta aatgtaactc
    16201 catgttacct gttcctttaa attcttcgta aatcatatcg tccatacgtg aacccgtatc
    16261 aactaatgca gttgcaagta ttgttaaact tccacccgct tcaatatttc tcgctgcacc
    16321 gaagaatgct tttggtttgt gtaaagatgc aggatctaaa ccacctgata atgtacgacc
    16381 acttggtgga ataactaagt tataagcgcg tgctaatctc gttatagaat ccattaaaat
    16441 aatgacatct tccccaattt ctactaaacg ctttgcacgt tcaagtaata attcagctac
    16501 tttaacatgg tgttctggtg gttcgtcaaa cgttgaatga acgacttcag cagcttctac
    16561 tgagcgttct aaatctgtca cctcttcagg acgctcgcca actaacaaaa taaatagctt
    16621 tgcatctggt ttgttcgtac tgattgcatt cgctatttct tttaataacg atgttttacc
    16681 tgctttaggt ggcgccacta ttaaaccacg ttgacctaaa ccaatcggtg ttactaaatc
    16741 catgatgcgc gttgaataat tttgtgtttc tgtctctaat ttaatacgct catctggata
    16801 aagtggtgtc aaagcttgga aatgcggacg tttcttcact tcttctgcgt tatggtcatt
    16861 gacaaagtca acttgtaata agccataata tttttcgtta tctttaggtt ttctaacttt
    16921 cccagttact ttatccccac gtttaatttc aaaacgacga atttggctag cagatatata
    16981 aatatctttt tcccctttag aatagttcac tgttcttaaa aaaccataac catctggttg
    17041 tatatcatct aagatacctt ccatataata gttaccatct ttttccattt gtgcttccat
    17101 aatagctaga acaagttctt ttttatttaa tttactatag ttcgtcaact taagagtttt
    17161 agctttttga gtgagttcct tggtagtata gttcttgtac aattcgtgga atgattcata
    17221 ctgaggagat gtacgttctc tttcaggcat atagtttaca cccatttcat tattttttag
    17281 ttagtaagta atagataggc atgacaatgc ataaataact gtgctagcac aatcccatta
    17341 tgctaatccc caacctttta aatacatgaa taactatagc aaatttttat tttaattaca
    17401 aaatctattt ataaaaattg caaaattaaa acagtacaca aaacttaatt agtcatgtgc
    17461 actgttttat tgcgattttt aattcaaaaa tcaaatttat ttaaaatatc cagctataga
    17521 tttcacttct aagaactctt caataccata atcgccccat tcacgaccta aaccagattg
    17581 tttatagcca ccaaatggta aatctggctt tctacctgct tcgtttattt ctactgtacc
    17641 tgcttcaata gaacgagcta ctttatgcaa tgtttctttg tccttaccaa taacatatcc
    17701 tgccaaacca tattttgtat catttgcaat ttgaatcgct tcatctaaat cgttataagt
    17761 gataactgac attactggcc caaaaatttc ttcttgtgct atcgtcattt gattatctac
    17821 attaataaaa attgtcggac gtgcaaagta tcctttttca agtccttctg gtttaccagg
    17881 accaccataa aataattcag caccttcttc aataccttta ttaatataat tttgtacttg
    17941 atcaaattgt tttttactaa tgatagggcc tacttgtgta ccatcttctc ttggattacc
    18001 gacacgcact tggctaaatt gttcttttaa ttcagctaag aatgcatctt taattttgtt
    18061 aggcactaaa acacgtgtac cagctgtaca tacttgacca gtattattaa caactttgcc
    18121 tgttgttgct ttagccgctt ctttaatatc tacgtcatct aggacgatat atggtgattt
    18181 gccaccaagc tctaatgata cctttttaaa atctttagcg gctttttcca taattttaga
    18241 accagtaggg cctgatcctg tgaatgacat catgcgtact ttaggatgtt cagataaagg
    18301 attcccaaca ccagcaccat caccattaac aaggttaaat acacctttag gaacaccgac
    18361 tttatcaaaa atctcagcta aaataacagc tgcaaatggt gtttcttcag atggtttaag
    18421 tacaactgga ctaccagccg caaatgctgc tgctaatttt aatgatgttt ggtttgtagg
    18481 gaagttccac ggtgtaatta atccagatac accgattgct tctttaacaa ctaaatcatc
    18541 tccgcggcgt tcttcaaatt cgtagttatc taatgcgtct ctcgctgcaa caaaatggtt
    18601 tagtcccatt tgataatgga cacgctcaga taatgataaa ggagcaccta attcatccgt
    18661 aatagcttgt acaatatcgt cttttctgtt ttcatattct tttacaattt tatctaataa
    18721 cgcttgtctt tctttcacag atgtatgacg gaactctaaa taaacatcgt ctgccgcctc
    18781 gacggcttta tcaacatcag ctttattacc tttagcaact ttcccgatta cttcttcggt
    18841 tgctggattt ataacttcta tcgtttcatt actattactt tctacccatt cgccattaat
    18901 gtattgcttt gtgtagtctc tcattattct ttcactcctc aagaatgatt tatatattat
    18961 ttatccgtaa tgcatacgat ataaacatta cattccatta tgatacgctc cattttaata
    19021 tgttcaaaat aaaatgcttt aaaattttgc tgcatctatt tttttatatt tttaaataaa
    19081 aataactatt cccacatcat cgcaaataat gcgaagactt agaaatagtt ataatcaatg
    19141 ctatgtttaa acgtcatgta attatttagc agtacgttga tctgttaaat cgacatatga
    19201 ttgcgcccat gcttcaattg gatgtaaagc ctctgctaac gctttacctt tttcagttag
    19261 cacataaata atttgtactg gactcgtaga aatgatttgc ttctcaacta actcccattg
    19321 tgcaagctct gacaacttaa gacttaaagc acgtggtgtt attgttttca aatctctttt
    19381 catatcggaa aagtgtgctg aacagtcatt acatcttgag agataattaa tgattaatcc
    19441 attccaactt ctaccaagta ttttaaaagt ttcttcgaga tacggacata cttccatcat
    19501 cttcacctct catcaataaa tttagaatgt aaacgaacac ccttttttaa tcagtataat
    19561 tattatacca caaaacaaga taaatctata cagtttccgt ccaaatatct gcacctaaag
    19621 cttttaagtg ttctacaata tctgtataac ctctataaat atgttttaca ttgtaaattg
    19681 tagttacacc ctcagcaatt aaaccagcaa taattaaaca agctcctgct cttaaatcgc
    19741 tagcataaac ttcagcacca tgtaatgttg atggttttat cgttgctgtg ccttcgtcaa
    19801 cttcaatatt tgcacccatg cgctttaatt cttcaacatg tttaaaacgc tccggataaa
    19861 tcgtatcagt tacaaatgaa ggaccatttg ccataaataa taatggtgta ataggctgtt
    19921 gcaaatcagt agcaaaacct ggatatacta gtgttttaat atcaacaaat tgatatggcg
    19981 cattattatt gatgcgaatt ctttcgtctc ttacatcaac attcacacct aattcactaa
    20041 atttagcagt taatgtttct acatgtttcg gaacaatatt atttaatata acattttctc
    20101 cacatgctgc agcgatacac atatatgtgc ctgcttcaat tctatcaggt ataacttgat
    20161 actcagaacc atgtaattct ttgacaccat tgattttaat tgttgatgtg cccgctccct
    20221 taatattagc tcccatactt gttaagaagt tagcaacatc aactacttcc ggttctttag
    20281 cagcattttc aattacagtt tgtcctgttg cataaactgc agctagcata atgttaattg
    20341 ttgcacctac gctaaccata tctagaaaaa tatgcgcacc ttttaattct ttagcttcaa
    20401 ttttcattga tgtcgtgctt gattcatcaa tttcagcacc taaagcttta aatcctttaa
    20461 tatgttgatc aattggacgt ggcccaagtg gacatcctcc cggtaaacca atcacacatt
    20521 ttttaaatct acctaacatg gcacccatca tatagtatga agcacgtaat gattcaactt
    20581 tattatttgg taatgcagca ttttgtattt cagttgtatc aacttctaat tccgtaccat
    20641 ttagtgatgc cttaatattt aaatcttcta ataaactcac taaagtttta acatcagaga
    20701 tttgcggtaa cccttctaat ttcacatgtc cttgagctaa taatgttgca ggaatgatag
    20761 ctacagcact gtttttcgcg ccactgatat taacttcccc atttagtgtg cgtccacctc
    20821 ttatttttat tacctcttga gccatatcat ttatctcctt tgtccattac tttttaattt
    20881 tttgcattat tagcattata aattaatttt actttatttg taaaatagtt tattttaatc
    20941 gttaaaatct tgtctttcta ttttcgattg attaataaca aatcattcac ctttactaat
    21001 atatgctgtt cttccccact tgaccatggt ctaaagtctg attattcaac taaatattga
    21061 cgttgttttg ataattattt agttttaatt ctacgatttg tacgtaaact tttttcataa
    21121 attgctcatt ttccttataa ttatatcaca atcaattttg gtatatttta ccatttttac
    21181 gctttcattt taaaatcaaa ctgttttatt tattacttat acgacataaa aaagaagtaa
    21241 acaccatttt gtctgcttct tttaaaatta atatccctac gttattaata acttaaaaac
    21301 taaatattaa ttatttagcg cggtttgaag taccgaactc tttaatttta cctttaactg
    21361 tttctttgat ggcttcacgt gcaggtccta agtatttacg aggatcgtaa acttctttgt
    21421 cgttatttaa aacgtcacga actgcttttg ctgaagcgat ttggttttca gtgtttacgt
    21481 taattttagc tgtaccaaat ggaattgctt tttggatatc tttagtcggg ataccagtac
    21541 caccgtgtaa tactaatggt aaacctgtag ataaaccgat ttcttccatt tctttaaatc
    21601 ctaattttgg ttcacctttg tatggaccat gaactgaacc taatgctggc gctaatgcat
    21661 caataccagt tttttcaact agttcttgac attctttagg atcagcataa atgatgccgt
    21721 ctgctacaac atcatcttct tgtccaccaa cagtacctaa ttcagcttct acagaaacac
    21781 ctttttcatg agcgtattca acaacttttt tagttgttgc tacgttttct tcgaatgggc
    21841 tgtgtgaagc atcgatcatt actgatgtga aaccagcatc gatagcttct ttacattttt
    21901 caaagcttga accatggtct aaatggattg ctacaggaat agtgatgttt aagtcatgca
    21961 ttaacccttc aaccatttta acaattgtgt agaaaccgct catgtaacga gcagcacctt
    22021 cagaaacacc taaaattaca ggtgcatttt cttcttgtga cgcttctaaa attgcttgag
    22081 tgaattctag gttattaata ttgtattgac ctaccgcata accattttct tttgcatcaa
    22141 ttaacatttc tttcattgaa actaaaggca tgaaagttcc tccttgagtg cttacgcacg
    22201 tatttttcaa agtaattata tcaaaaaaat agcgtcaatg cattgaaata ctgcagatta
    22261 aatgtgtatt ttttgaaaaa tgcgatagtt atactaaatg caaacgtata catttttata
    22321 caatttaagc cgttgcataa tatgtagtca ttaattacaa tattttataa gtagattgga
    22381 ggataaagat gtcaaaaatc ttaaacacac aactaatagg tatctttaat aggctagaaa
    22441 aacaatcttt agaaattcaa atggccgccc aatgtttaat tcaagcaatt ggtggcgaag
    22501 gttatgttta tgtaaaaggt tatgatgatt tacagttttt cgaaagtttc attctacata
    22561 gtgatgagcg tttaaaatct agccgaaaac ttgacgctat taaagacttt aaagaaattg
    22621 actcaactga tcgtgtatta ttattcgcac cattttataa tgatcaagtt gcattagata
    22681 ttcaaaaact tatcgactta gatatcgatg tggtcttaat aagcaacaaa cctaaaacag
    22741 atgatttccc tgatcatctc gtacatttta tcgatttatc tacaccaaga cctatagtct
    22801 atactgaaga ttatgataag attgtccagc cacatgcgat agcattgaat tatgtatact
    22861 atgacattta tacacaaatg attgaaatga caagagactt agaattataa aagtcactat
    22921 tgttatttca taccttgtca ctaacataat attaaaatta tacgaaaaac cggtactttc
    22981 aatgtttaac aatgaaagta ccggttttat tagcaaattt atttattttg ttgatatttt
    23041 aatgaagctt caataaatga tttaaaaatc gggtgcggac gatttggtct agataagaat
    23101 tctgggtgga attgacaagc aataaagaaa tcatttgtcg gaatctctac catttctact
    23161 aaacgtccat ctggacttgt accagaaatt accataccat ttgcttctaa ttgttctcta
    23221 tagtcattat taaattcata acgatgacga tgtctttctt caatttccgc tttaccataa
    23281 acatcttgtg ccaatgtgcc ttctttaata gaacatggat ataagcctaa gcgtaatgta
    23341 ccacctaaat cttcgatatc tttttgttct ggtaataaat ctataattgg gtatggtgtt
    23401 gctgggtcta attcagctga atgtgcgcct tcaagtccta atacgtttct tgaaaattca
    23461 actgttgcaa gttgcattcc taaacaaata ccaaagaatg gtacattgtt ttctctagca
    23521 tacttaattg cactaatttt accttcactt gcacggaaac caaatccacc tggtactaaa
    23581 ataccgtcga catctgcaag gtattcggct gcattttcat ctgttacttc acttgaatca
    23641 atccatctaa tgtcaatatc tttggcaaaa ggatatccag catgtttcaa tgattcaaca
    23701 actgataaat atgcatcttg taagctaaca tatttaccta ctaaaccaat tgtaatttta
    23761 ccatctaaat tattaacgat atctaacaac tgtttccatt catcaagctg tgtttcatat
    23821 ttcgcgttta attgtaaacg tttaataacg atatcatcca tattttgttg gcttaattgt
    23881 aatggaattt cgtataaaga gtctgcatca cgacattcaa taacactttc tttattaatg
    23941 tcacagaata atgcaatttt atcttttaaa tcttgtgtca tttcatattc agttcttaca
    24001 acgattaagt ctggttgaat acctaagcct cgtaattctt taacactatg ttgtgttggc
    24061 ttcgttttca tttctccagc agctttaata taaggcagta atgtacagtg aacatacata
    24121 acattttctc tacctaaatc gctacgaatt tgacgaatcg cttcaataaa cggtaatgac
    24181 tcaatatcac ctgttgtacc gccaatttca gtgataacaa cgtctgcatt cgtactttcc
    24241 cctgcaagta ataaacgttc tttaatttca tttgtaatat gcggaataac ttgaactgtt
    24301 ccgcctaagt aatcaccacg acgttctttt ttcaatacgt gtgaatacac tttaccggct
    24361 gtcacatttg aaaacttgtt taaattaata tcaataaatc tttcgtaatg tcctaagtct
    24421 aggtcagttt ctgcaccatc atccgttacg aatacttcac catgttgata aggactcatt
    24481 gtacctgggt caacatttaa gtatggatcg aatttttgaa ttgttacatt tagacctcta
    24541 tcttttaata atctacctag agaagatgct gtaataccct tccctaatga tgaaactacg
    24601 ccacctgtta caaaaataaa ttttgtcatg tcttgacctc ctaattatta aagggaatgc
    24661 ttcctcatca attgtaaaaa ttacgtaaaa cataacatta aagcaagctc attcaagttg
    24721 tttatttgtc gaattcgaca aaattaaatt ctgtttactt accgtttcca tactgctatg
    24781 tcactatgta tatcatttac aactttgatt tttgcgttat catttcttga tttactcaat
    24841 taaataaaaa aacgctccct ctcacaaatt ctgtaagggg agcgtataaa ttttatacac
    24901 gtgtcctatt taaaggagcc cgaataaaat tttatcatct ttcaactaaa agtcaaacaa
    24961 aaaattaatc gttgaagtct tcttcgtctt caaacacttc ttcgtcttcg tctagttcat
    25021 cttcatcttc ttcaatgact atatccgaat gattgatttc ttcttcaacc tgctcatctt
    25081 ctggatcatt tagttcttct tgatcatctg tttgagctgg aatatcatcg tcgtcatcca
    25141 tttcatcttc gcccaataat tttaagtttt gatcttcttc atcatctgca tccagaatat
    25201 cgaatttttg aatagttggt gcgattttct cttcaatatc atctaccgaa taccaatcac
    25261 gtaatcccca taaattttct ccaacattta aaaaacgacc atctgtgttt aaatctgtgt
    25321 aaaattgtac aacgcgattt tcaatttctt cgtactcata atcacctaac gctctaaact
    25381 catcgatgat atcatataag ttcatagttt cgcctttatc attcaataat gtataagcca
    25441 tatcaataaa tgatttttca tcaaccattt gttttgtata atcttgaatt ttcattgccc
    25501 aatacttcct ttcgaaggat ataatctaaa tttatacgtc tgaattcatt tatatatagt
    25561 aacaaaacta aattataaat gacaatatca tatttcgcaa tcactgttag taatttaaat
    25621 atttttcaaa aacgacataa tcatcagttt gttcgatttc aacgaaatta ctatttaaac
    25681 ataatggttt aaaatcatta ttctctccaa acagaatcat cgtaatcaca ttaaggttgt
    25741 catagttttt tcttaagtaa gttggcaatt gtcgcagcgc acttgaacca ataccattaa
    25801 agcgatatga tttatccact tcaatagcag caatgttcat gcgttcacca atctgctcca
    25861 atgcgataaa gccaaccttt tggccatcaa tcattaaatt aatgatatgt acattggtca
    25921 cttctgaacg actttcttct tcaagcttta atgacgaaac atgttttgaa tctaagtcca
    25981 agtaatatag tcgttctttg ccaattggtc cttcttcttt agtcgctgta tgcatgaatc
    26041 cagcacgttc gtataggttc caagcattgt cattttccgc atctactact agatatagat
    26101 gattaaaatc aggaaataca ccttgaacat attgcggcaa tgacatcatt attttcgtgc
    26161 catatccaaa accttgatat ttttcattaa tcgataatga acgaatataa acgacatttt
    26221 caggtgtatc ataaccttca tgctgatagt aacgatgtaa tacaaaaaag cccaccactt
    26281 catttttatc gtttattgct acgttagcaa tcctatcaac atcattaatt gcatcatcaa
    26341 taacttcttt aggtaaagat gaatatattt gttgtctttc attcaagtca aaatcattaa
    26401 ttgctgaacg atattgttca tcaaatgctt ttaaagtgat accttcaaaa caaagttctt
    26461 tagccatata tttaacccct atctttttat atatgaagca tgaatcccca tattatttta
    26521 cctattattt cactacgata ccattattta ctctaagtta aataaattac ttatttatat
    26581 ttttttaaat ttcaaaatta atgtgctatt cctcattact catcatttta atcagagact
    26641 tacaaataca ctgcgtacga actactttta atattgcgtc actaactaac aatcctatac
    26701 aacttcaaaa ttcctagaaa ataatatata taacttaacg tctacgtttg taatacatta
    26761 attgcgatgc gcttacaata tcgaaataca atggcatcaa atttgttaat aattactatt
    26821 attacttgtt ttttagtcat tttactatac tattatttaa ggatagacat taataatgag
    26881 gtgggaatct tatgaaagtt ggcattgacg ctggcggtac actaattaaa atcgttcaag
    26941 agcaagataa ccaacgtact tttaaaactg aattaactaa aaatattgat caagttgtgg
    27001 aatggttaaa ccaacagcaa attgaaaaat tatgcttaac tggaggtaat gcaggtgtca
    27061 ttgctgaaaa catcaacatt cctgcacaaa tttttgtaga gtttgatgct gcatctcaag
    27121 gactaggtat tttgttaaaa gagcaaggcc atgacttagc agattatatt tttgcaaatg
    27181 ttggtaccgg tacgtcacta cattatttcg acggccaatc acaacgtcgt gtaggcggta
    27241 tcggtacagg tggaggcatg attcaaggac tcggttattt actaagtcaa atcactgatt
    27301 ataaacagtt aactgacatg gcacaacacg gtgatcgtaa cactatcgat ttaaaggtta
    27361 gacatattta taaagatacc gaaccaccca ttcccggtga tttaacagca gctaattttg
    27421 gtcatgtact acatcattta gatgctgatt ttacacctag caataaatta gcagccgtta
    27481 ttggtgtcgt tggcgaagtt gttacgacaa tggccattac tgttgcacgt gaatttaaaa
    27541 ctgaaaatat cgtttatatc ggttcttcat tccataataa cgctttatta cgcaaagttg
    27601 tggaagatta tactgtgtta cgcggttgca aaccgtacta tgttgaaaac ggcgcatttt
    27661 caggtgctat tggtgcatta tatttaggta aatagaaaaa gaccatttat atgcgcgttg
    27721 ttttaaataa acgctatata aatggccttt tattttatgg tctacgtgtt ttggaatacg
    27781 tattgttcca tttattatca cttaattact tacaactcaa ttcaattaaa atgtaagttc
    27841 attagacaat ttttgcgctg aaacaattgt accaaccacg ccagttttta aatctattgc
    27901 aacggcttta tgatcatctc taagttcatc tagccattct ccgaaaacag aaccttcaat
    27961 cgtaattaaa tcacactctt caaaatcttc atctcgaact tttaacgctc tgtttttaat
    28021 actccataca ggcataatat gcggcttttt ttcgtcgcta tcattttcac taatgagaat
    28081 aaactgctta ctaccttttt tagttaagcc gtatacttca tcatattttg ctacatcttg
    28141 gacaaattct ttgattctaa ttttatctaa ttccgtcatc acttcttgtg taacagctac
    28201 aacgtttagt agatgccctt cttcttccat tgtttgattc ataataatat ggtcttgttc
    28261 atcaaacaat tcatctaatt cataagtagc aaaacgatca acgtccattt ttacaacttt
    28321 atcaaatgga atatcacgac ttgttaaaaa tgatacggcc acactttctt ctgtccaaac
    28381 gcctacatac gcttcacttt tataatttag gcgtactagt tttttatttt tagaggcgaa
    28441 ataaatacat tcatttatta atatatctct aaagaatgga tatgctttat aagacatgct
    28501 tgaccctcac tttttaaaat atgtcataca taaaatagta aatgactcca acaagttagt
    28561 caattagaca tattatgaat tcaatttaat gtcatgtttt tcattttaaa aattcaatag
    28621 cattaaattt tacgtataca caaattcggt ctataacacg aaacatatct agttactaaa
    28681 aatttcaaaa cgataacctt tagtatacct ttatcaacaa aatggcaact cttataacat
    28741 agtgaaataa aagtcgccat ttaatattag tattacaaag tattgccata tcataaattt
    28801 aattactgtt gactagaatc gaaaaaagct tgttacaaac gcatattcag tcaactactg
    28861 gcaacacaac attgtagcgc cttatgttcc gaactctaat agtgttcaag ttcagctaaa
    28921 aatgcgcgtt cattctccag tactgtttct tttgaatcac catgccaaat acagccaaac
    28981 cttgatttaa ctttatcttc accgtaccaa tcaccatcat aataagataa cgggtataaa
    29041 ctaccttctt tgacatattt caaaatcgta ttgaagaaat gtgtgttatc accttttgaa
    29101 tgataactat aaaacttttg atatcctgaa ttcaactcgt tagcaagtaa taacatgctc
    29161 gttgaaccat tttgtctaaa gtttaaatca atcgcataaa cgttatcatc ctcatcgacg
    29221 agtaggtcaa aaccagctac accaaagaat ccttgattca caccgttttc cataatttgt
    29281 ctacctgctt ctataacgtg ctctggtaca ttagtagtat tttcatttcc gttataaaat
    29341 ccgtacttat ccgttaattg cgttgccgca ccaagatatt gaatgcctag cgattccgag
    29401 tatgcaaact gaacgcaata attcgctttt tcttcaatct tctgttcgat aataagcgaa
    29461 ttcgtttcag cagttgcctc tttaatacgc gttatcgctt tttgtaaatc tgcatcatga
    29521 taacaaatca taacgccata gccacctgct gtcggaagat catctcccgg cttaattact
    29581 aacgggaatt cccaattctt aatctcgttt tcgaattgct caatttttac aacttttctt
    29641 tttggtaaaa acttcccatt tgtccattca ggtattcttg ctttattatt taaagcaaca
    29701 aataacgttt tatctaatgc ataatattgc tgattcaaga ttgtttcatc atgaatatat
    29761 tgaaaataaa tctttttatt ttccttatgt gccaattgtt tgatcaagtt ttcgtaagat
    29821 tgctgattgt taaatgtaaa aattgagttc ggtacttcct taccaataac ttgaaatagc
    29881 tgatgcaatt tgtctgtcgc actagcttcg tgaacaataa caggtaattg atttgctatt
    29941 aataactccc taccagttaa aaaattagat tgatgttcgt ccggtttcaa ccatggattc
    30001 gatatatacg aaggtcttga cgtatagaca acatctttgt catataaatc acttaacgtt
    30061 aagttcggct cattaccatt atttgtcatt acttcccatt ccctttcaaa tgcgcatgct
    30121 cttcaataat gtcttgataa acgtcttgat ttgtaattaa ctctaacccc atcaacgcca
    30181 ttattttagc acctttaatt aatgcttcat caccatgtac actcgcagcc gcctctctaa
    30241 atctatgcgt atgtcctact aaattacgtg atcctatttt aatatgagga tgtattgttg
    30301 gcacaacatg acttacgttc cctgtatccg tagagccata accaaaatca tcatcaataa
    30361 ctgcttcacc aacttcttca gcatatttag caaataaatc atctaatttc ggcgttttaa
    30421 tgaattcatt cacaccgttt tgaattggac caaattcata atcacaacca gtctgtatcg
    30481 cagctccacg tgcgatttga tttacttttt ctgttaatat atccaattct ttacgcgtca
    30541 ttgctctagt ataaaaacga gcatgtgtat agtctggaat aatattagct gctttcccgc
    30601 catctaaaat cacaccatgc acacgttgat cttttttaat atgttgtcgt agttgtgcta
    30661 caccattaaa ataactaatc atagcgtcta atgcatttaa cgcttcatct gcattttcag
    30721 aggcatgagc actttttccg taaaatttaa catctaaaac atccactgcc aaagtatcaa
    30781 tcgttttata agtttcattt cccggatgaa tcattaaggc aatgtctatt tgatcaatca
    30841 caccagcctt gacataagaa gctttagcgc taccattttc cccaccttct tcagctggac
    30901 atccaagaac gactacttta ccaccaattt ggtcaatcac ttgcttcaaa ccaattgcac
    30961 caagcacact tgcagttcca atgatattat gaccacaagc atgacccaac cctggcaaag
    31021 catcgtattc tgctaaaaaa cctatagctg gcccgtcaag acctgaatca tatgtcgcta
    31081 taaacccagt tgcatgccca gcaatctcgg tttcaatttc aaaatcatgc tctttcaaac
    31141 gatctattaa agttcgagac gcaaatattt cttcattacc aagttcagga cgttcatgaa
    31201 ttctatgact gatttcgata taactatatt tatttgtttc tatataatcg agaatttgtt
    31261 gtttttcact cattttttac tatctccctt ttaccctaca ctcattttaa tcatccacaa
    31321 tattttgttc tttcaaaatg aattattact tattctatcg gttttatctc atgatgtcat
    31381 ctagtttttc tttatttaca aaattttcta ataactaaaa gcctttcata aatttataaa
    31441 acagtttcaa attgtaaaac ataagcccta ttgttacaat ttaagtattg ttagaaacac
    31501 aacttacaac aaacttaagt tttatattgc aacaaatcat aagcgtttta tagttttgag
    31561 tagtaaatag gaggaaattc aaaatgacaa aaatgaatgt tgaaagtttc aatttagatc
    31621 atactaaagt ggttgcccca tttattagat tagcgggaac gatggaagga ttaaacggag
    31681 atgtcattca caaatacgac attcgtttca aacaaccaaa caaagaacat atggatatgc
    31741 caggactaca ttcattagaa catttaatgg ctgaaaatat tagaaatcat agtgacaaag
    31801 ttgttgattt aagtcctatg ggttgccaaa ctggtttcta tgtatcattt attaatcatg
    31861 ataattatga tgatgtatta aatattgttg aagcaacttt aaatgatgtg ctaaatgcta
    31921 ctgaagtgcc tgcttgtaat gaagtacaat gtggctgggc agcaagtcat tcattagaag
    31981 gtgctaaaac tatcgctcaa gcatttctag acaaacgaaa cgaatggcat gatgttttcg
    32041 gtacaggaaa ataaatctta gtcaatcaag ttaatcagaa aagcagtcga acaatgatgt
    32101 tacaatcgcc attgtccaac tgctttttat tatgcttcaa agtcaaaaaa tcgaacaaat
    32161 gaaaaagtaa aatctttaac atttgtccga tttatttgag aaccactata atttcttaat
    32221 tagtcccatt aacacgaact gcataggtaa ccttaaatat agttgccatg ttggcaattg
    32281 tttatctcct aaaggtaact ttttaactgc catatagata ttagctggga atacagctag
    32341 caagaataga ttgattgtat ttttcaagca ttgagatggt cttttaatta aaagtgcaag
    32401 tccaaataat atctcaaaga ttcctgtaac aagaaccgct gtttttcgaa gtggcaaaca
    32461 tttcggtatg atatttctaa attgtcgttc tcgtgtaaaa tgcaatacac ctattacact
    32521 aaaacctatt cctaataaat atcttagtat gttcaatcag cttcaactcc tactctgtaa
    32581 tgattttatg aattaatgta ggcgatacaa catgatcagc aattgttatg cttgaatcta
    32641 attttttaac aacatcgtct acatcttggc gattactgtg aatcgttaat aatgattctc
    32701 cttcttctac tttatcacca atttttttat ttaaaacaat accaaccgct aaatcaatat
    32761 catcctcttt tgttaaacgt cccgctccta acatcatcga agcgacacct atatcgttag
    32821 agactaattc agtcacataa cctgattttt tagctttata ttcaatttga tattgagctt
    32881 gtggcaaacg ctctggatgg tcaataacag tttcgtcgcc accttggttt ttaataaatg
    32941 ttttgaattt ttctaatgct gcacctgaat taattgcctc aattagcaac gctctcgctt
    33001 cttcaagcgt ttcagctttg tttgcaagta caaccatttg agaacctaat gttaatacaa
    33061 gttctgttaa atctttcgga ccttgtcctt tcaacgtatc aattgcttct tgtaactcaa
    33121 gcgcattgcc aatcgcacgt ccaagtggct gattcatatc agaaataatc gccatcgtat
    33181 tacgtcccac attattacca atacgtacca ttgcgtgcgc taatgcttca gcatcttcta
    33241 atgttttcat aaatgcaccg ctaccagttt ttacatctaa tacaattgca tctgcaccag
    33301 cagcaatctt tttactcata attgaagagg caattaatgg tattgaattg acagtaccag
    33361 taacatccct taaggcatat aattttttgt ctgcaggagt taaatttcct gattgtccta
    33421 caactgccac tttattttca ttaaccaatt tcacaaatgt tgcttcatct atttcaacat
    33481 gaaaaccatc aattgcttct aatttatcaa tcgtaccacc tgtatgacct aatccacgcc
    33541 cactcatttt tgcaacagga acatctacag ctgctactaa tggtgctaaa accaatgtag
    33601 ttgtatctcc tacaccacct gttgagtgct tatctacttt gacaccttta atatcactca
    33661 aatctatcat atcaccagaa ttaaccatag ccatcgttaa tgctgcacgc tcatcatcat
    33721 tcatatcttg gaaataaatc gccattgcta aacttgatgc ttggtaatca ggaatatccc
    33781 ctttaacata gccgtcaata aagaaattaa tttcttccgt tgttagtgta tgaccgtcac
    33841 gctttttctc aataatgtct atcattctca tttttatcat ccttttctta aaaagcttag
    33901 gacaaagcat ctgcgctttc tctagtccat ttttaaaagc acaagcgaaa attattatag
    33961 caagctatcg atttcatttt taatatcaca atttcaatgc gatgttatta ttcttaaata
    34021 gattggttat aacgttaaag tccctattaa attatcttag aatcatcatg gcatttatga
    34081 tgtcttaaag ctgatatcga catacttata tatggttacg atgtcccatg cttacatatt
    34141 tttataaaat tagtaatctg aatctgcttc taaaccttgc ataatttgaa cgcctgcgct
    34201 cgcaccaata cgtgtcgcac ctgcttcaac cattttattg aaatcttcta aattacgtac
    34261 gccacctgat gcttttactt ctacatcagc acctactgta tctttcatta atttaacgtc
    34321 ttctgcagtc gcaccgccac ctgcaaaacc tgttgaagtt ttaacgaagt ccgcaccagc
    34381 cacttttgtt aattcactcg cttttacgat ttcgtcatgg tccaacaata ccgtctcaat
    34441 aatcactttt actgtgtgac ctttcgcagc tttcaccact gcttcaatgt cttgttgtac
    34501 atcatcaaaa cgtccatctt ttaatgcgcc gatgttgatg accatgtcaa tttcatctgc
    34561 accattttga atcgcatctt ctgtttcaaa tgctttcgtc gcagttgtcg atgcacctaa
    34621 tgggaatcct attaccgtac aaactaacac ctctgaatca gctagtcgct ctgctgcata
    34681 tttaacatgc gttggattca cacatacaga tttaaaatgg tatgctttcg cttcatcgat
    34741 gatttgatcg atttgcgtac gtgttgactc aggcttcaat aaagtgtgat caatcaattt
    34801 tgcactattc atttctatct cctcctttat ggttgattat aaaaatacgg ttgtaaatta
    34861 gttgattgag cgtcaggttc atttaaatat caggttagat gttcgctttt tatgtaaccg
    34921 catacatata ctattacatt aattcatttc ccataaacaa acaatacaat tgaacgtgat
    34981 atcttcatta tgaacgatga cttgacaaca agctaatcag gattatattt ttataattct
    35041 ttaattctat agtacaaaaa ttcgcaaaaa agggaaacaa atgttatctt aaaattatta
    35101 atgaatatta aggagaagat aacaaatgac aaaaggtaca ccacatattc aaccaaatgg
    35161 agtaaaaatt gctaaaacag tattaatgcc tggcgatccg ctacgcgcaa aatatattgc
    35221 tgataatttt ttagaaaatg ttgaacaatt taacgatgta cgtaacatgt ttggttacac
    35281 tggtacatat aaaggtaaag aagtttctgt aatgggttct ggtatgggta ttccaagtat
    35341 tggtatttac tcatatgagt tatacaactt ctttgatgta gatacaatca ttcgtatcgg
    35401 ttcttgtggc gcattacaag aaaatgttaa cttatacgat gttattattg cacaagctgc
    35461 atcaactaat tcaaattatg tagatcaata caatattcca ggtcatttcg cgcctatcgc
    35521 tgacttcgag ttagtaacta aagctaaaaa tgtcgctgac caaatcggtg ctactacaca
    35581 cgtaggtaac gtattatctt ctgatacatt ttacaatgcc gatccaacat tcaatgatgc
    35641 ttggaaaaaa atgggtattt taggtatcga aatggaatca gctggtttat atttaaatgc
    35701 gattcatgct ggtaaaaaag cacttggtat tttcacagta agtgatcata ttttacgtga
    35761 cgaagctact acacctgaag aacgtcaaaa ttcatttaca caaatgatgg aaatcgcttt
    35821 agaaatcgca gagtaactta tttaaattga ctttaattgc tctttaacaa tgcgattaaa
    35881 ctcaaaaagc caacacattc tgggcgtatc cccatttatg tgttggcttt tatttatatt
    35941 attacttatc tgtagattag cttaagtaag atttaaacat ccaattatgt ttatctactg
    36001 atgtttgcat acctataaac atatcttctg atacatcatc gccagcatta ccagcaattt
    36061 cgattgcgtt ttctaattgt tttgagatat ttgtgaagtc ttgtgataat tcttcaacca
    36121 tttgttctgc agagtaacct ttcgcagctt ctttaacaat tgattgctct aagcattcag
    36181 ttaatgtacc tacagggttt cctcctaccg ctaaaattct ttcagctaat tcgtctacat
    36241 attggcttgc ttcattatat aattcttcaa atttaacgtg taatgagaag aagttaggtc
    36301 ctttcacata ccagtggaaa ttatgtagct ttgtgtaagc tactgtccag tttgctactt
    36361 gttgattcaa ttcttttaca acatcttgtt gattactcat atttaataca ctccttaaaa
    36421 ttgtctacgt cttgcttgtt tatattaatt attatattat aatgattcta atctgtaaag
    36481 tgtttttact ctctttttta taattattct aatctaaatg taaggtgttc cgctttttaa
    36541 atgtctaaat tttaattcat catctagtat atccattatc aattagcaag tatgttttat
    36601 caatcagtaa gttttacttt cgcattatca tctaaaaaga acgatttttc ataatcattt
    36661 ggttggtgcc atgttgtttt ccacattcta tttctattat tagcaaacat tcgataaccg
    36721 aaattacgga ctggtttagg tacaagccat aaacctacgc ccaataattt agttcgatta
    36781 ggtagtgctg tgattagttt aataatcgcc tgcgattcaa aatatatacg atcacctttc
    36841 tgtaaaatca cactattttt atttgccgct tctggatgtt gtttaaaaaa ttgttgtcca
    36901 acttcacctt ttaacgtggc aaattgataa tttcttggta ggtcatgttg aattaaccaa
    36961 atgacatagt tataacaata tatacagttt ccatcataat atacgattgg cataatttat
    37021 tcgctccttt aatagtactt atagtcattt ttcctaattt aaaaacattt aaacaaggtt
    37081 gtcacttgat aagtcctcgc gacacgaaat tgccataaaa tttatttttc agttttatat
    37141 ttattgtata atgtattttt tatttacttt aaatttctca atctacagtg taatcttatt
    37201 tcttattatt aacttagcgt ttggtcattc gtcttattca acatacgact ggaaaactca
    37261 tataaagttt taatt
//
LOCUS       DAPDIM010000025        36698 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000025 DAPDIM010000000
VERSION     DAPDIM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 36698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36698
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.025"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(204..1202)
                     /gene="sirC"
                     /locus_tag="RFE25_001297"
     CDS             complement(204..1202)
                     /gene="sirC"
                     /locus_tag="RFE25_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B ABC transporter permease
                     subunit SirC"
                     /protein_id="HDU2816368.1"
                     /translation="MTEKINKKDNYHLIFALIFLAIVSVVSMMIGSSFIPLQRVLMYF
                     INPNDSMDQFTLEVLRLPRITLAILAGAALGMSGLMLQNVLKNPIASPDIIGITGGAS
                     LSAVVFIAFFSHLTIHLLPLFAVLGGAVAMMILLVFQTKGQIRPTILIIIGISMQTLF
                     IALVQGLLITTKQLSAAKAYTWLVGSLYGATFKDTIILGMVILAVVPLLFLVIPKMKI
                     SILDDPVAIGLGLHVQRMKLIQLITSTILVSMAISLVGNIGFVGLIAPHIAKTIVRGS
                     YAKKLLMSTIIGAISIVIADLIGRTLFLPKEVPAGVFIAAFGAPFFIYLLLTVKKL"
     gene            complement(1199..2194)
                     /gene="sirB"
                     /locus_tag="RFE25_001298"
     CDS             complement(1199..2194)
                     /gene="sirB"
                     /locus_tag="RFE25_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B ABC transporter permease
                     subunit SirB"
                     /protein_id="HDU2816369.1"
                     /translation="MLLKPKYQIVIAGLCLAIVAILSLMIGNTLVSPGTVIQALFNFD
                     SENDLHDVVTGARASRTIIALLTGAALAVSGLLMQALTRNPIASPGLFGVNAGAVFFV
                     IFSITFIQIQSFKMIVVIAFLGAIVVTILVVALGMFRQTLFSPHRVILAGAAIAMLFT
                     AFTQGILIMNETDLQGLLFWLSGSVSLRNIWDIPWIIPLVLILILIAFSMAAHINILM
                     TSDDIATGLGQNIKLIKWMIIMLISMLAGISVAVAGSIVFVGLIVPNISKRLLPPNYK
                     YLIPFTALAGAILMIISDIVARIIIKPLELPIGVVTAVIGAIVLIYIMKKGRQRL"
     gene            complement(2210..3202)
                     /gene="sirA"
                     /locus_tag="RFE25_001299"
     CDS             complement(2210..3202)
                     /gene="sirA"
                     /locus_tag="RFE25_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B ABC transporter
                     substrate-binding protein SirA"
                     /protein_id="HDU2816370.1"
                     /translation="MNKVIKMLVVTLAFLLVLAGCSGNSNKQSSDNKDKETTSIKHAM
                     GTTEIKGKPKRVVTLYQGATDVAVSLGVKPVGAVESWTQKPKFEYIKNDLKDTKIVGQ
                     EPAPNLEEISKLKPDLIVASKVRNEKVYDQLSKIAPTVSTDTVFKFKDTTKLMGKALG
                     KEKEAEDLLKKYDDKVAAFQKDAKAKYKDAWPLKASVVNFRADHTRIYAGGYAGKILN
                     DLGFKRNKDLQKQVDNGKDIIQLTSKESIPLMNADHIFVVKSDPNAKDAALVKKTESE
                     WTSSKEWKNLDAVKNNQVSDDLDEITWNLAGGYKSSLKLIDDLYEKLNIEKQSK"
     gene            3433..4413
                     /gene="sbnA"
                     /locus_tag="RFE25_001300"
     CDS             3433..4413
                     /gene="sbnA"
                     /locus_tag="RFE25_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000570808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="HDU2816371.1"
                     /translation="MIEKSQACHDSLLDSVGQTPMVQLHQLFPKHEVFAKLEYMNPGG
                     SMKDRPAKYIIEHGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKIS
                     PTNLKIIKSYGANVEMVEEPDAHGGYLMTRIAKVQELLATIDDAYWINQYANELNWQS
                     HYHGAGTEIVETIKQPIDYFVAPVSTTGSIMGMSRKIKEVHPNAQIVAVDAKGSVIFG
                     DKPINRELPGIGASRVPEILNRSEINQVIHVDDYQSALGCRKLIDYEGIFAGGSTGSI
                     IAAIEQLITSIEEGATIVTILPDRGDRYLDLVYSDTWLEKMKSRQGVKSE"
     gene            4410..5420
                     /gene="sbnB"
                     /locus_tag="RFE25_001301"
     CDS             4410..5420
                     /gene="sbnB"
                     /locus_tag="RFE25_001301"
                     /EC_number="1.5.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate
                     dehydrogenase SbnB"
                     /protein_id="HDU2816372.1"
                     /translation="MNREMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPL
                     KPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILN
                     DPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLE
                     QFDHIKRVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQ
                     PYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFS
                     KEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLN
                     LY"
     gene            5441..7195
                     /gene="sbnC"
                     /locus_tag="RFE25_001302"
     CDS             5441..7195
                     /gene="sbnC"
                     /locus_tag="RFE25_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B biosynthesis protein SbnC"
                     /protein_id="HDU2816373.1"
                     /translation="MQNHTAVNTAQAIILRDLVDALLFEDIAGIVSNSEITKENGQTL
                     LIYERETQQIKIPVYFSALNMFRYESSQPITIEGRVSKQPLTAAEFWQTIANMNCDLS
                     HEWEVARVEEGLTTAATQLAKQLSELDLASHPFVMSEQFASLKDRPFHPLAKEKRGLR
                     EADYQVYQAELNQSFPLMVAAVKKTHMIHGDTANIDELENLTVPIKEQATDMLNDQGL
                     SIDDYVLFPVHPWQYQHILPNVFATEISEKLVVLLPLKFGDYLSSSSMRSLIDIGAPY
                     NHVKVPFAMQSLGALRLTPTRYMKNGEQAEQLLRQLIEKDEALAKYVMVCDETAWWSY
                     MGQDNDIFKDQLGHLTVQLRKYPEVLAKNDTQQLVSMAALAANDRTLYQMICGKDNIS
                     KNDVMTLFEDIAQVFLKVTLSFMQYGALPELHGQNILLSFEDGRVQKCVLRDHDTVRI
                     YKPWLTAHQLSLPKYVVREDTPNTLINEDLETFFAYFQTLAVSVNLYAIIDAIQDLFG
                     VSEHELMSLLKQILKNEVATISWVTTDQLAVRHILFDKQTWPFKQILLPLLYQRDSGG
                     GSMPSGLTTVPNPMVTYD"
     gene            7188..8444
                     /gene="sbnD"
                     /locus_tag="RFE25_001303"
     CDS             7188..8444
                     /gene="sbnD"
                     /locus_tag="RFE25_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B export MFS transporter"
                     /protein_id="HDU2816374.1"
                     /translation="MINQSIWRSNFRILWLSQFIAIAGLTVLVPLLPIYMASLQNLSV
                     VEIQLWSGIAIAAPAVTTMIASPIWGKLGDKISRKWMVLRALLGLAVCLFLMALCTTP
                     LQFVLVRLLQGLFGGGVDASSAFASAEAPAEDRGKVLGRLQSSVSAGSLVGPLIGGVT
                     ASILGFSALLMSIAVITFIVCIFGALKLIETTHMPKSQTPNINKGIRRSFQCLLCTQQ
                     TCRFIIVGVLANFAMYGMLTALSPLASSVNHTAIDDRSVIGFLQSAFWTASILSAPLW
                     GRFNDKSYVKSVYIFATIACGCSAILQGLATNIEFLMAARILQGLTYSALIQSVMFVV
                     VNACHQQLKGTFVGTTNSMLVVGQIIGSLSGAAITSYTTPATTFIVMGVVFAVSSLFL
                     ICSTITNQINDHTLMKLWELKQKSAK"
     gene            8434..10170
                     /gene="sbnE"
                     /locus_tag="RFE25_001304"
     CDS             8434..10170
                     /gene="sbnE"
                     /locus_tag="RFE25_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2,3-diaminopropanoate--citrate ligase SbnE"
                     /protein_id="HDU2816375.1"
                     /translation="MQNKELIQHAAYAAIERILNEYFREENLYQVPPQNHQWSIQLSE
                     LETLTGEFRYWSAMGHHMYHPEVWLIDGKSKKITTYKEAIARILQHMAQSADNQTAVQ
                     QHMAQIMSDIDNSIHRTARYLQSNTIDYVEDRYIVSEQSLYLGHPFHPTPKSASGFSE
                     ADLEKYAPECHTSFQLHYLAVHQDVLLTRYVEGKEDQVEKVLYQLADIDISEIPKDFI
                     LLPTHPYQINVLRQHPQYMQYSEQGLIKDLGVSGDLVYPTSSVRTVFSKALNIYLKLP
                     IHVKITNFIRTNDLEQIERTIDAAQVIASVKDEVETPHFKLMFEEGYRALLPNPLGQT
                     VEPEMDLLTNSAMIVREGIPNYHADKDIHVLASLFETMPDSPISKLAQVIEQSGLAPE
                     AWLECYLDRTLLPILKLFSNTGISLEAHVQNTLIELKDGIPDVCFVRDLEGICLSRTI
                     ATEKQLVPNVVAASSPVVYAHDEAWHRLKYYVVVNHLGHLVSTIGKATRNEVVLWQLV
                     AHRLMTWKKEYANNAVFVDCVEDLYQTPTIAAKANLMSKLNDCGANPIYTHIPNPICY
                     NKEVSYCESNNS"
     gene            10079..11929
                     /gene="sbnF"
                     /locus_tag="RFE25_001305"
     CDS             10079..11929
                     /gene="sbnF"
                     /locus_tag="RFE25_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(L-alanin-3-ylcarbamoyl)-2-[(2-
                     aminoethylcarbamoyl)methyl]-2-hydroxypropanoate synthase
                     SbnF"
                     /protein_id="HDU2816376.1"
                     /translation="MIVVQTLFIHIYQIQFVITRRYRIVNQTILNRVKTRVMHQLVSS
                     LIYENIVVYKASYQDGVGHFTIEGHDSEYRFTAEKTHSFDRIRITSPIERVVGDEADT
                     TTDYTQLLREAVFTFPKNDEKLEQFIVELLQTELKDTQSMQYRESNPPATPETFNDYE
                     FYAMEGHQYHPSYKSRLGFTLSDNLKFGPDFVPNVKLQWLAIDKDKVETTVSRNVVVN
                     EMLRQQVGDKTYEHFVQQIEASGKHVNDVEMIPVHPWQFEHVIQVDLAEERLNGTVLW
                     LGESDELYHPQQSIRTMSPIDTTKYYLKVPISITNTSTKRVLAPHTIENAAQITDWLK
                     QIQQQDMYLKDELKTVFLGEVLGQSYLNTQLSPYKQTQVYGALGVIWRENIYHMLIDE
                     EDAIPFNALYASDKDGLPFIEKWIKQYGSEAWTKQFLAVAIRPMIHMLYYHGIAFESH
                     AQNMMLIHENGWPTRIALKDFHDGVRFKREHLSEAASHLTLKPMPEAHKKVNSNSFIE
                     TDDERLVRDFLHDAFFFINIAEIILFIEKQYGIDEQRQWQWVKDIIEAYQEAFPELNN
                     YQHFDLFEPTIQVEKLTTRRLLSDSELRIHHVTNPLGVGGINDATTISET"
     gene            11904..12680
                     /gene="sbnG"
                     /locus_tag="RFE25_001306"
     CDS             11904..12680
                     /gene="sbnG"
                     /locus_tag="RFE25_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B biosynthesis citrate synthase
                     SbnG"
                     /protein_id="HDU2816377.1"
                     /translation="MQQLSLKHRLNNGDSVYGIFNSIPDPLMIEVIAASGYDFVVIDT
                     EHVAINDETLAHLIRAAEAAHIIPIVRVTAVIDRDIIKVLDMGARGIIVPHVKDRETV
                     EHIVKLSRYYPQGLRSLNGGRMARFGRTPLLDAMEMANEHIMVIAMIEDVEGVMAIDD
                     IAQVEGLDMIVEGAADLSQSLGIPWQTRDDQVTSHVQHIFEVVNAHGKHFCALPREDE
                     DIAKWQAQGVQTFILGDDRGKIYRHLSASLATSKQKGDDG"
     gene            12680..13882
                     /gene="sbnH"
                     /locus_tag="RFE25_001307"
     CDS             12680..13882
                     /gene="sbnH"
                     /locus_tag="RFE25_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B biosynthesis decarboxylase
                     SbnH"
                     /protein_id="HDU2816378.1"
                     /translation="MRIVQPVIEQLKAQSHPVCHYIYDLVGLEHHLQHITSSLPSNCQ
                     MYYAMKANSERTILDTISQYVEGFEVASQGEIAKGLAFKPANHIIFGGPGKTDEELRY
                     AVSEGVQRIHVESMHELQRLNAILEDEDKTQHILLRVNLAGPFPNATLHMAGRPTQFG
                     ISEDEVDDVIEAALVMPNIHLDGFHFHSISNNLDSNLHVDVVKLYFKKAKSWSEKHRF
                     PLKHINLGGGIGVNYADLTSQFEWDNFVENFKTLIVEQEMEDVTLNFECGRFIVAHIG
                     YYVTEVLDIKKVHGAWYAILRGGTQQFRLPVSWQHNHPFEIYRYKDNPYSFEKVSISR
                     QDTTLVGQLCTPKDVFAREVQIDAISTGDVIVFKYAGAYGWSISHHDFLSHPHPEFIY
                     LTQTKEDE"
     gene            13886..14650
                     /gene="sbnI"
                     /locus_tag="RFE25_001308"
     CDS             13886..14650
                     /gene="sbnI"
                     /locus_tag="RFE25_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional transcriptional
                     regulator/O-phospho-L-serine synthase SbnI"
                     /protein_id="HDU2816379.1"
                     /translation="MNHIHEHLKLVPVDKIDLHETFEPLRLEKTKSSIEADDFIRHPI
                     LVTAMQHGRYMVIDGVHRYTSLKALGCKKVPVQEIHETQYSISTWQHKVPFGVWWETL
                     QQEHRLPWTTETRQEAPFITMCHGDTEQYLYTKDLGEAHFQVWEKVVASYSGCCSVER
                     IAQGTYPCLSQQDVLMKYQPLSYKEIEAVVHKGETVPAGVTRFNISGRCLNLQVPLAL
                     LKQDDDVEQLRNWKQFLADKFANMRCYTEKVYLVEQ"
     gene            14846..15472
                     /locus_tag="RFE25_001309"
     CDS             14846..15472
                     /locus_tag="RFE25_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2816380.1"
                     /translation="MEKNVEKSFIKIGLYFQIAYIVLMAITLCGFVICYGLIFGLFYL
                     LSGSRADYLIVTIVISAIISIFVIILSIVPVIVLASDLFKERISKGVILIVLAIIALV
                     LCNFVSAILWFVSAISILGRKKLVAAADTTTIQKSKGNANQASHKDTCKKELDSQDMM
                     EHPEVKNPTTKNLEGFNEEIHKDEATTKVVSDNTEPPIESKGHVSKKD"
     gene            15684..16460
                     /locus_tag="RFE25_001310"
     CDS             15684..16460
                     /locus_tag="RFE25_001310"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HDU2816381.1"
                     /translation="MTNNKVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAA
                     ALKLSSDGTKAIAIKADVSNRDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITE
                     EQFKTVYGVNVAGVLWGIQAAHEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFA
                     VRGLTQVAAQDLASEGITVNAFAPGIVQTPMMESIAVATAEEAGKPEAWGWEQFTSQI
                     ALGRVSQPEDVSNVVSFLAGKDSDYITGQTIIVDGGMRFR"
     gene            16604..16726
                     /locus_tag="RFE25_001311"
     CDS             16604..16726
                     /locus_tag="RFE25_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816382.1"
                     /translation="MHQLKALLVLTHPRYYKTSQKHHYLIYLNKNSQSYLILFL"
     gene            16796..17776
                     /locus_tag="RFE25_001312"
     CDS             16796..17776
                     /locus_tag="RFE25_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDU2816383.1"
                     /translation="MEDLERVLITGGAGFIGSHLVDDLQQDYDVYVLDNYRTGKRENI
                     KSLADDHVFELDIREYDAVEQIMKTYQFDYVIHLAALVSVAESVEKPILSQEINVVAT
                     LRLLEIIKKYNSHIKRFIFASSAAVYGDLPDLPKSDQSLILPLSPYAIDKYYGERTTL
                     NYCSLYNIPTAVVKFFNVFGPRQDPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDF
                     VYVYDVVQSVRLIMEHKDAIGHGYNIGTGTFTNLLEVYRIIGELYGKSVEHEFKEARK
                     GDIKHSYADISNLKALGFVPKYTVETGLKDYFNFEVDNIEEVTAKEVEMS"
     gene            17739..18431
                     /locus_tag="RFE25_001313"
     CDS             17739..18431
                     /locus_tag="RFE25_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDU2816384.1"
                     /translation="MKKLQLKKWKCRENDIEAVHNNKGYAYQRKLDALEEVRKGYYPI
                     KRAIDLVLSIVLLFLTFPIMFIFAIAIVIDSPGNPIYSQVRVGKMGKLIKIYKLRSMC
                     KNAEKNGAQWADKDDDRITNVGKFIRKTRIDELPQLINVVKGEMSFIGPRPERPEFVE
                     LFSSEVIGFEQRCLVTPGLTGLAQIQGGYDLTPQQKLKYDMKYIHKGSLMMELYISIR
                     TLMVVITGEGSR"
     gene            18641..19807
                     /locus_tag="RFE25_001314"
     CDS             18641..19807
                     /locus_tag="RFE25_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDU2816385.1"
                     /translation="MKIIYCITKADNGGAQTHLIQLANHFCVHHDVYVIVGNHGPMIE
                     QLDARVNVIILEHLVGPIDFKQDILAVKVLAQLFSKIKPDVIHLHSSKAGTVGRIAKF
                     ISKSKDTRVVFTAHGWAFTEGVKPAKKFLYLVIEKLMSCITDSIICVSDFDKQLALKY
                     RFNRLKLTTVHNGIADVPAVKQTLKSQSHNNIGEVVGMLPNKQDLQINAPTKHQFVMI
                     ARFAYPKLPQNLIAAIEILKLHNSNHAHFTFIGDGPTLNDCQQQVVQAGLENDVTFLG
                     NVINASHLLSQYDTFILISKHEGLPISIIEAMATGLPVIASHVGGISELVADNGICMM
                     NNQPETIAKVLEKYLIDSDYIKMSNQSRKRYLECFTEEKMIKEVEDVYNGKSTQ"
     gene            19788..21026
                     /locus_tag="RFE25_001315"
     CDS             19788..21026
                     /locus_tag="RFE25_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDU2816386.1"
                     /translation="MENQHNSKLLTLLLIGLAVFIQQSSVIAGVNVSIADFITLLILV
                     YLLFFANHLLKANHFLQFFIILYTYRMIITLCLLFFDDLIFITVKEVLASTVKYAFVV
                     IYFYLGMIIFKLGNSKKVIVTSYIISSVTIGLFCIIAGLNKSPLLMKLLYFDEIRSKG
                     LMNDPNYFAMTQIITLVLAYKYIHNYIFKVLACGILLWSLTTTGSKTAFIILIVLAIY
                     FFIKKLFSRNAVSVVSMLVIMLILLCFTFYNINYYLFQLSDLDAVPSLDRMASIFEEG
                     FASLNDSGSERSVVWINAILVIKYTLGFGVGLVDYVHIGSQINGILLVAHNTYLQIFA
                     EWGILFGALFIIFMLYLLFELFRFNISGKNVTAIVVMLTMLIYFLTVSFNNSRYVAFI
                     LGIIVFIVQYEKMERDRNEE"
     gene            21016..22446
                     /locus_tag="RFE25_001316"
     CDS             21016..22446
                     /locus_tag="RFE25_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDU2816387.1"
                     /translation="MKSDSLKENIIYQGLYQLIRTMTPLITIPIISRAFGPSGVGIVS
                     FSFNIVQYFLMIASVGVQLYFNRVIAKSVNDKRQLSQQFWDIFVSKLFLALTVFAMYM
                     VVITIFIDDYYLIFLLQGIYIIGAALDISWFYAGTEKFKIPSLSNIVASGIVLSVVVI
                     FVKDQSDLSLYVFTIAIVTVLNQLPLFIYLKRYISFVSVNWIHVWQLFRSSLAYLLPN
                     GQLNLYTSISCVVLGLVGTYQQVGIFSNAFNILTVAIIMINTFDLVMIPRITKMSIQQ
                     SHSLTKTLANNMNIQLILTIPMVFGLIAIMPSFYLWFFGEEFASTVPLMTILAILVLI
                     IPLNMLISRQYLLIVNKIRLYNASITIGAVMNLVLCLVLIYFYGIYGAAIARLITEFI
                     LLIWRFVDITKINVKLNIVSTIQCVIAAVMMFIVLGVVNHYLPPTMYATLLLIAIGIV
                     VYLLLMMTMKNQYVWQILRHLRHKTI"
     gene            22714..23313
                     /locus_tag="RFE25_001317"
     CDS             22714..23313
                     /locus_tag="RFE25_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDU2816388.1"
                     /translation="MAFKLPNLPYAYDALEPYIDQRTMEFHHDKHHNTYVTKLNATVE
                     GTELEHQSLADMIANLDKVPEAMRMSVRNNGGGHFNHSLFWEILSPNSEEKGGVIDDI
                     KAQWGTLDEFKNEFANKATTLFGSGWTWLVVNDGKLEIVTTPNQDNPLTEGKTPILLF
                     DVWEHAYYLKYQNKRPDYMTAFWNIVNWKKVDELYQAAK"
     gene            23680..24405
                     /gene="sasD"
                     /locus_tag="RFE25_001318"
     CDS             23680..24405
                     /gene="sasD"
                     /locus_tag="RFE25_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070002951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-wall-anchored protein SasD"
                     /protein_id="HDU2816389.1"
                     /translation="MKKLATVGSLIVTSTLVFSSMPFQNAHADTTSMNVPNKQSQNVQ
                     NHRPYGGVVPQGMTQAQYTELEKTLPQLSAGSNMQDYNMKLYDATQNIADKYNVIITT
                     NVGVFKPHAVRDMNGHALPLTKDGNFYQTNVDANGVNHGGSEMVQNKTGHMSQQDHMN
                     QNTHMNQQPQIQQGHMQSSNHQMMSPKANMHSSNHQMNQSNKKVLPAAGESMTSSILT
                     ASIAALLLVSGLFLAFRRRSTNK"
     gene            complement(24596..25351)
                     /locus_tag="RFE25_001319"
     CDS             complement(24596..25351)
                     /locus_tag="RFE25_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDU2816390.1"
                     /translation="MEVVYVTQTQPKFLTIYNTLYKEIQIGKYPSGHALPTEKELCAR
                     FDVSRMTLRQAIKLLAEDGIVESTRGKGHFVIPQTNAQHASSMDQFKHPLDQILLARV
                     SMSSINYRVDLESEYTNHLFANHPSAVIAMERYYQKKDNHSKQADAFCFTFIPLNVID
                     TFKVNTQNEDDMKTFVEQTIYSNAYQSDLKMSITKAPRFKNHSHVFDGDTHCWLIIET
                     LYAQTPYPIMINKWYIPQEISELTLTRIRQSDY"
     gene            25587..26294
                     /gene="deoD"
                     /locus_tag="RFE25_001320"
     CDS             25587..26294
                     /gene="deoD"
                     /locus_tag="RFE25_001320"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDU2816391.1"
                     /translation="MKSTPHIKPMNDVEIAETVLLPGDPLRAKFIAETYLDDVEQFNT
                     VRNMFGFTGTYKGKKVSVMGSGMGMPSIGIYSYELIHTFGCKKLIRVGSCGAMQENID
                     LYDVIIAQGASTDSNYVQQYQLPGHFAPIASYQLLEKAVETARDKGVRHHVGNVLSSD
                     IFYNADTTASERWMRMGILGVEMESAALYMNAIYAGVEALGVFTVSDHLIHETSTTPE
                     ERERAFTDMIEIALSLV"
     gene            26301..27653
                     /gene="tet(38)"
                     /locus_tag="RFE25_001321"
     CDS             26301..27653
                     /gene="tet(38)"
                     /locus_tag="RFE25_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(38)"
                     /protein_id="HDU2816392.1"
                     /translation="MNVEYSKIKKAVPILLFLFVFSLVIDNSFKLISVAIADDLNISV
                     TTVSWQATLAGLVIGIGAVVYASLSDAISIRTLFIYGVILIIIGSIIGYIFQHQFPLL
                     LVGRIIQTAGLAAAETLYVIYVAKYLSKEDQKTYLGLSTSSYSLSLVIGTLSGGFIST
                     YLHWTNMFLIALIVVFTLPFLFKLLPKENNTNKAHLDFVGLILVATIATTVMLFITNF
                     NWLYMIGALIAIIVFALYIKNAQRPLVNKSFFQNKRYASFLFIVFVMYAIQLGYIFTF
                     PFIMEQIYHLQLDTTSLLLVPGYIVAVIVGALSGKIGEYLNSKQAIITAIILIALSLI
                     LPAFAVGNHISIFVISMIFFAGSFALMYAPLLNEAIKTIDLNMTGVAIGFYNLIINVA
                     VSVGIAIAAALIDFKALNFPGNDALSSHFGIILIILGLMSIVGLVLFVILNRWTQSEK
                     "
     gene            27734..28396
                     /gene="deoC"
                     /locus_tag="RFE25_001322"
     CDS             27734..28396
                     /gene="deoC"
                     /locus_tag="RFE25_001322"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDU2816393.1"
                     /translation="MKFEKYIDHTLLKPESTRTQIDQIIDEAKAYNFKSVCVNPTHVK
                     YAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRF
                     DDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKAAGADFVKTSTGFAGGG
                     ATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADS
                     DY"
     gene            28424..29602
                     /gene="deoB"
                     /locus_tag="RFE25_001323"
     CDS             28424..29602
                     /gene="deoB"
                     /locus_tag="RFE25_001323"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDU2816394.1"
                     /translation="MTRPFNRVHLIVMDSVGIGEAPDAADFKDEGSHTLRHTLEGFDQ
                     TLPNLEKLGLGNIDKLPVVNAVEQPEAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFK
                     VYPNGFPEELIQQIEEMTGRKVVANKPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQ
                     IAAHEDIIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALK
                     PFGKTVLDHLKDGGYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMKIVKKDFTG
                     ISFLNLVDFDALYGHRRDKPGYAQAIKDFDDRLPELFSNLKEDDLVIITADHGNDPTA
                     PGTDHTREYIPVIMYSPKFKGGHALESDTTFSSIGATIADNFNVTLPEFGKSYLKELK
                     "
     gene            complement(29731..30546)
                     /gene="phnE"
                     /locus_tag="RFE25_001324"
     CDS             complement(29731..30546)
                     /gene="phnE"
                     /locus_tag="RFE25_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDU2816395.1"
                     /translation="MTQEIAKYNVHTKAHKRKLIKRWLIAIVVLAIIIWAFAGVPSLE
                     LKSKSLEILKSIFSGLFHPDISYIYIPDGEDLLRGLLETFAIAVVGTFIAAIICIPLA
                     FLGANNMVKLRPVSGVSKFILSVIRVFPEIVMALIFIKAVGPGSFSGVLALGIHSVGM
                     LGKLLAEDIEGLDFSAVESLKASGANKIKTLVFAVIPQIMPAFLSLILYRFELNLRSA
                     SILGLIGAGGIGTPLIFAIQTRSWDRVGIILIGLVLMVAIVDLISGSIRKRIV"
     gene            complement(30543..31343)
                     /gene="phnE"
                     /locus_tag="RFE25_001325"
     CDS             complement(30543..31343)
                     /gene="phnE"
                     /locus_tag="RFE25_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDU2816396.1"
                     /translation="MPLEIPTKYDSLLKKKVSLKTSFTFMLIIVLIIWSFIYTGFNFG
                     DLMIGIPQIGDLFKQMIPPDFEYLQQITTPMLDTIRMAIVSTVLGSIVSIPIALLCAS
                     NIVHQKWISIPSRFILNIVRTIPDLLLAAIFVAVFGIGQIPGILALFILTICIIGKLL
                     YESLETIDPGPMEAMTAVGANKIKWIVFGVVPQAISSFMSYVLYAFEVNIRASAVLGL
                     VGAGGIGLFYDQTLGLFQYPKTATIILFTLVIVVVIDYISTKVRAHLA"
     gene            complement(31345..32118)
                     /gene="phnC"
                     /locus_tag="RFE25_001326"
     CDS             complement(31345..32118)
                     /gene="phnC"
                     /locus_tag="RFE25_001326"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HDU2816397.1"
                     /translation="MSQIEFKNVSKVYPNGHVGLKNINLNIEKGEFAVIVGLSGAGKS
                     TLLRSVNRLHDITSGEIFIQGKSITKAHGKALLEMRRNIGMIFQHFNLVKRSSVLRNV
                     LSGRVGYHPTWKMVLGLFPKEDKIKAMDALERVNILDKYNQRSDELSGGQQQRISIAR
                     ALCQESEIILADEPVASLDPLTTKQVMDDLRKINQELGITILINLHFVDLAKEYGTRI
                     IGLRDGEVVYDGPASEATDDVFSEIYGRTIKEDEKLGVN"
     gene            complement(32313..33269)
                     /locus_tag="RFE25_001327"
     CDS             complement(32313..33269)
                     /locus_tag="RFE25_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDU2816398.1"
                     /translation="MKNFKYLFVLMLAVIVFAAACGNSSSLDNQKNASNDSDSKSGGY
                     KPKELTVQFVPSQNAGTLEAKAKPLEKLLSKELGIPVKVSVSTNYNTIVEAMKSKKVD
                     VGFLPPTAYTLAHDQKAADLLLQAQRFGVKEDGSASKELVDSYKSEILVKKDSKIKSL
                     KDLKGKKIALQDVTSTAGYTFPLAMLKNEAGINATKDMKIVNVKGHDQAVISLLNGDV
                     DAAAVFNDARNTVKKDQPNVFKDTRILKLTQAIPNDTISVRPDMDKDFQEKLKKAFID
                     IAKSKEGHKIISEVYSHEGYTETKDSNFDIVREYEKLVKDMK"
     gene            33498..35042
                     /locus_tag="RFE25_001328"
     CDS             33498..35042
                     /locus_tag="RFE25_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDU2816399.1"
                     /translation="MKKIYKSLTVSAIVATVSLSALPQSLAITHESQPTKQQRTVLFD
                     RSHGQTAGVADWVSDGAFSDYADSIQKQGYDVKAIDGHSNITEASLKSSKIFVIPEAN
                     IPFKESEQAAIVNYVKQGGNVVFISDHYNADRNLNRIDSSEAMNGYRRGAYEDMSKGM
                     NAEEKSSTAMQGVKSSDWLSTNFGVRFRYNALGDLNTSNIVSSKESFGITEGVKSVSM
                     HAGSTLAITNPEKAKGIVYTPEQLPAKSKWSHAVDQGIYNGGGKAEGPYVAISKVGKG
                     KAAFIGDSSLVEDSSPKYVREDNGEKKKTYDGFKEQDNGKLLNNITAWMSKDSDGKSL
                     KASGLTLDTKTKLLDFERPERSTEPEKEPWSQPPSGYKWYDPTTFKAGSYGSEKGADP
                     QPNTPDDHTPPNQNVKISFDIPQNVSVNEPFEVTIHLKGFEANQTLENLRVGIYKEGG
                     RQIGQFSSKDNDYNPPGYSTLPTVKADENGNATIKINAKVLESMEGSKIRLKLGDKTL
                     ITTDFK"
     gene            35093..36628
                     /locus_tag="RFE25_001329"
     CDS             35093..36628
                     /locus_tag="RFE25_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDU2816400.1"
                     /translation="MSNIAFYVVSDVHGYIFPTDFTSRNQYQPMGLLLANHVIEQDRR
                     QYDQSFKIDNGDFLQGSPFCNYLIAHSGSSQPLVDFYNQMAFDFGTLGNHEFNYGLPY
                     LKDTLRRLNYPVLCANIYENDSTLTDNGVQYFQVGDQTVGVIGLTTQFIPHWEQPEHI
                     QSLTFHSAFETLQQHLPEMKRHADIIVVCYHGGFEKDLENGTPTEVLTGENEGYAMLE
                     AFSKDIDIFITGHQHRQIAERFKQTAVIQPGTRGTTVGKVVLSTDEYENVSVESCELL
                     PVIDDSTFTIDEDDQHLRKQLEDWLDYEITTLPYDMTINHAFEARVAPHPFTNFMNYA
                     LLEKSDADVACTALFDSASGFKQVVTMRDVINNYPFPNTFKVLAVSGAKLKEAIERSA
                     EYFDVQNDEVSVSADFLGPKPQHFNYDIYGGVSYTIHVGRPKGQRVSNMMIQGHAVDL
                     KQTYTICVNNYRAVGGGQYDMFIDAPVVKDIQVEGAQLLIDFLSNNNLMRIPQVVDFK
                     VEK"
BASE COUNT        12283 a         5771 c         6976 g        11668 t
ORIGIN      
        1 tatttgaaaa atcgaagaat attgattgat attatagaat atgagtcggt gttatttgta
       61 tataaagtat taatatgtaa ttaagaaagt cgacgcttgt taacaataac aacaactata
      121 tgtataaaaa aacctcgcaa ctgttagtta actgaatcat ttagctaact tcgttgtgag
      181 gtcattttgt tttaataata tcgttataac tttttcacgg ttaataataa gtatatgaag
      241 aatggggcac caaaagcagc aataaataca cctgctggca cttctttagg caagaataag
      301 gtacgcccaa ttaagtctgc aataacaatt gatatggcac caataattgt tgacattagt
      361 aactttttag cataacttcc gcgaacgatt gttttcgcga tatgtggtgc gattaaaccg
      421 acaaacccaa tgttacctac taaactgatt gccatagata cgagtatagt agaagtgatt
      481 aattggatta gtttcatacg ttgtacatgt aagcctaagc caatcgctac agggtcatca
      541 agtatagata ttttcatttt tggtataaca agaaataaca acggcacaac agctaaaata
      601 accataccca aaatgattgt atctttaaac gtagcaccgt aaagacttcc gactagccat
      661 gtataagctt tggcagcaga taattgcttc gttgtaatga gtaatccttg gacaagcgca
      721 ataaacaacg tttgcatcga aataccgatg attatgagta ttgtcgggcg tatttgtcct
      781 ttcgtttgaa acactaatag tatcatcatt gcaactgcgc cacctaatac tgcaaatagt
      841 ggaagtaaat gtatcgttaa atggctgaaa aatgcaataa agacaacagc acttaagcta
      901 gcaccacctg tgataccgat aatatcaggt gaggcaattg gattttttaa tacattttgc
      961 aacattaaac cactcattcc tagtgcggca cctgctaaaa tcgcaagtgt aatgcgaggt
     1021 aagcgtaata cttctaaagt gaattgatcc atactgtcat ttggatttat aaagtacatc
     1081 agtacgcgtt gtaatggtat aaagcttgaa ccaatcatca tacttaccac tgaaacgatg
     1141 gctaaaaaga ttaacgcgaa gatgagatgg taattgtctt ttttattaat cttttcggtc
     1201 ataagcgttg acgtcctttc ttcataatat agattaagac aatagcgcca atgacagcgg
     1261 taacgacacc gataggcaac tctagtggct taattattat acgagcaaca atgtctgaaa
     1321 tgatcattag gattgctcca gctaatgcag taaaaggaat taaatactta tagtttggtg
     1381 gtaataatcg tttgctaata ttcggtacga taagacccac aaagacgatt gatccagcta
     1441 cggctaccga aataccggct aacatactga tgagcataat aatcatccat ttgattaatt
     1501 ttatgttttg accgaggccg gttgcaatgt cgtcacttgt catcaagatg ttgatgtgtg
     1561 cagccatgct aaatgcaatt aaaataagta tcaatacaag cggaataatc catgggatat
     1621 cccaaatatt acgtaatgaa acggagccac ttaaccaaaa taataggcct tgtaagtctg
     1681 tttcgttcat aataagtatg ccttgagtaa aggctgtaaa tagcatcgca atcgcagcac
     1741 ctgccaaaat gacacggtga ggtgagaata gtgtttgtct aaacatacct agcgcaacaa
     1801 ctaatatagt aacaacaatg gcacctaaaa atgcaataac tacaatcatt ttaaaagatt
     1861 gaatttggat aaatgtaata ctaaaaatga caaaaaatac tgcgcctgca ttgacaccga
     1921 aaagccctgg tgaggctatt gggtttcgtg taagtgcttg catcaacaaa cctgagacag
     1981 caagggcagc accagtcaat aacgcaatga ttgttctcga cgcccgtgca ccagtgacaa
     2041 catcatgtaa atcgttttca ctatcaaagt tgaataacgc ctgtatcacc gtacctggtg
     2101 acacaagcgt atttccaatc attaaactta agatagctac tattgcaaga cataaaccag
     2161 caataacgat ttggtatttt ggtttaagta gcatcgtaaa actccttaat tattttgatt
     2221 gtttttcaat atttaacttt tcatataaat cgtcaataag ttttaatgaa gatttatatc
     2281 cgccagctaa gttccaagtg atttcatcta aatcatcaga tacttggttg tttttaactg
     2341 cgtctaaatt tttccactct ttacttgaag tccattcgct ttcagtcttt ttaactaatg
     2401 cagcatcttt cgcatttgga tctgatttta ctacaaaaat atgatcagcg ttcattaatg
     2461 gaatgctttc tttagatgta agttggataa tatctttacc attatcaact tgtttttgta
     2521 agtctttatt acgtttgaat cctaaatcat ttaagatttt accagcatat ccaccagcat
     2581 aaattcttgt atgatcagca cggaagttaa caactgaagc tttcaatggc catgcatctt
     2641 tatactttgc ttttgcatct ttttggaatg cagctacttt atcatcgtac tttttaagta
     2701 aatcttcagc ttctttttct ttccctaaag ctttccccat taacttagtt gtatctttga
     2761 atttgaaaac tgtatcagta gaaactgttg gtgcgatttt agataattga tcgtaaactt
     2821 tttcatttct aacttttgac gcgacaatta agtccggttt taatttagag atttcctcta
     2881 agttaggtgc aggttcttga cctacaatct tagtatcttt taaatcattt tttatgtatt
     2941 cgaatttcgg tttttgtgtc catgattcta cagcacctac aggtttaaca cctaaagata
     3001 cagcgacgtc agtggcacct tgatatagcg taacaacacg ctttggtttc cctttaattt
     3061 cagttgtacc cattgcatgt ttaattgaag ttgtttcctt atctttgtta tcagatgatt
     3121 gtttatttga attcccacta catcctgcta aaacaagtag gaaagcaagc gtaacaacaa
     3181 gcattttaat tactttattc attgactaat tagcctcctt cgtgatgtat gacaatgaga
     3241 atcattatca cgatttagta tgaattaaat tttttcctaa gtcaataaaa tatttatgat
     3301 ttacatgcaa cttataatta tttgacatat aaatgcataa aaaatataat cctaattact
     3361 tgatagtgag aatcattatc aattaggtaa cacacaatat tatagaattt taaatttgag
     3421 gaggaagcgc ttttgattga aaaaagtcaa gcatgtcacg attcattgtt agattctgta
     3481 gggcaaacac ctatggttca acttcatcaa ctatttccga aacatgaagt gtttgcaaag
     3541 ttagagtata tgaatcctgg aggcagcatg aaagatcgac ctgccaagta catcattgaa
     3601 catggtatta aacatggttt aatcactgag aatacacatt taattgaaag tacttctggt
     3661 aatttaggca ttgcgttggc aatgatagct aaaatcaagg gattaaaact cacgtgtgtt
     3721 gttgatccta aaatatcacc aacaaatttg aaaattatta aaagttatgg tgccaatgta
     3781 gaaatggttg aagaacctga tgcacatggg ggttatttaa tgactcgtat tgcaaaggtg
     3841 caagaactgt tagccactat tgacgatgca tattggatta atcaatatgc gaatgagtta
     3901 aattggcaat cccattatca tggtgcaggc acagagattg ttgaaacaat taagcaacct
     3961 atagattatt ttgtcgcgcc agtcagcacg acaggtagca ttatgggtat gagtagaaaa
     4021 ataaaagaag tgcatccaaa cgcacaaatt gttgctgttg atgcgaaagg gtcagtcatt
     4081 tttggtgaca aacctattaa tagagaatta cctggtatcg gtgctagtcg tgtacccgaa
     4141 atattgaata gatcagaaat taatcaagtg atccatgtag atgattatca atctgctttg
     4201 ggctgtcgaa aactgattga ttatgaaggc atatttgccg gaggttcaac aggctcgatt
     4261 attgcagcga ttgagcagtt gataacgtca attgaagaag gtgcaacaat tgtcacgatt
     4321 ttaccagatc gaggcgatcg ttacttagat ttagtttatt cagatacatg gttagaaaaa
     4381 atgaaatcaa gacaaggagt taaatcagaa tgaatagaga gatgttgtat ttaaatagat
     4441 cagatattga acaagcggga ggtaatcatt cacaagttta tgtggacgca ttaacagaag
     4501 cattaacagc ccatgcgcac aatgattttg tacaaccgct taagccgtat ttaagacagg
     4561 atcctgaaaa tggacacatc gcagatcgaa ttattgcaat gccaagtcat atcggtggtg
     4621 aacacgcaat ttcaggtatt aagtggatag gtagtaagca cgacaatcca tcgaaacgta
     4681 atatggagcg tgcaagtggt gtcattattt tgaatgatcc agaaacgaat tatccaattg
     4741 cagttatgga agcaagttta attagtagta tgcgtactgc agcagtttca gtgattgcag
     4801 ctaagcattt ggctaaaaaa ggatttaaag acttaacaat cattggttgc gggctaatcg
     4861 gagacaagca attacaaagt atgttagagc aattcgatca tattaaacgc gtgtttgttt
     4921 acgatcaatt ctctgaagca tgtgcacgct ttgttgatag atggcaacaa cagcgtccgg
     4981 aaattaattt tattgcgaca gaaaatgcta aagaagcagt atcaaatggt gaagtagtca
     5041 ttacatgtac cgtaacggat caaccataca ttgaatatga ttggttacaa aagggtgcat
     5101 ttattagcaa catttctatc atggatgtgc ataaagaagt ctttattaaa gctgacaaag
     5161 tcgtagtaga tgactggtca caatgtaatc gagaaaagaa aactattaac caattggtgt
     5221 tagaaggtaa attcagcaaa gaagcacttc atgctgaact agggcaactt gtgacaggtg
     5281 acataccagg acgtgaagac gatgatgaaa tcatattact taatccgatg ggtatggcta
     5341 tcgaagatat ttcaagtgct tattttattt atcaacaggc acaacaacaa aatattggga
     5401 caacattgaa cctatattaa gaatgcgagg tgtctgaaca ttgcagaatc atacagcagt
     5461 caatacagca caagcgataa tattaagaga tttagttgat gcattattat ttgaagatat
     5521 agccggaatt gtatcgaata gtgagattac taaagaaaac ggacaaacgc ttttgatata
     5581 cgaacgtgaa acacaacaaa taaagatacc tgtttatttt agtgctttaa atatgtttcg
     5641 ttacgaaagt tcacaaccaa ttacgataga gggaagggtg tctaagcaac ctttaacggc
     5701 agctgaattt tggcaaacaa ttgctaatat gaattgtgat ctaagtcatg aatgggaagt
     5761 ggctcgcgtt gaagaaggac tgactactgc tgccacacag cttgctaaac aattatcaga
     5821 attagattta gcgtcacatc cttttgtgat gtcagagcag tttgcaagtt taaaagatcg
     5881 tccatttcat ccattagcta aagaaaaaag aggattaaga gaagcggatt atcaagtgta
     5941 tcaagctgaa ttaaatcaat catttccttt aatggttgca gcagttaaaa agacacatat
     6001 gattcatggc gatactgcaa atatcgatga attagaaaat ttgacagtac ctataaaaga
     6061 acaagcgaca gacatgttaa atgatcaagg gttatcaata gatgactatg tactatttcc
     6121 ggtacatcct tggcaatatc agcatattct gccgaacgtc tttgcgacag agattagtga
     6181 aaagttggtt gtactattac cgttaaaatt tggagattat ctgtcgtctt caagtatgcg
     6241 ttcattaatt gatattggcg caccgtataa ccatgtcaaa gtaccatttg caatgcagtc
     6301 attaggcgca ttaaggctaa cgcctacgcg ttacatgaaa aacggagaac aagcagaaca
     6361 attattacgt cagcttatag aaaaagatga agcactagct aagtatgtca tggtttgtga
     6421 tgaaacagct tggtggtcat atatgggtca agataatgat attttcaaag atcaattagg
     6481 tcatctaact gttcagctaa gaaagtatcc cgaagtgcta gccaaaaatg atacgcaaca
     6541 gctagtgtca atggcagcac tcgcggcaaa tgatcgcact ttatatcaaa tgatttgtgg
     6601 aaaagataat atttctaaaa atgatgtcat gacgttattt gaagatatcg cgcaagtctt
     6661 tttaaaggta acactatcat ttatgcaata cggcgcatta ccagagttgc atggtcaaaa
     6721 tatattgttg tcatttgaag atggacgtgt acaaaaatgc gtgttacgtg atcatgatac
     6781 tgtcagaatt tataaaccat ggctaacagc acatcagctt tcattgccga agtatgtcgt
     6841 cagagaagat acacctaata cgctaattaa tgaggatttg gaaacattct ttgcttattt
     6901 tcaaacatta gctgtatcgg taaatctata tgccattatt gatgcaattc aagatttatt
     6961 tggtgtaagc gagcatgaac ttatgtcgtt gttaaaacaa attttaaaaa atgaagtggc
     7021 aactatttcc tgggttacaa ctgatcagct agctgtcaga cacattttat ttgataaaca
     7081 gacgtggcca ttcaaacaaa ttttattacc attgctatat caacgtgata gtggtggagg
     7141 tagtatgcct tcaggtttaa ctaccgtacc aaatccaatg gtgacatatg attaatcagt
     7201 ctatatggcg cagtaacttt cgcattttat ggctcagtca gtttatagcg attgctggac
     7261 tgacagtact tgtgccatta ttgccaattt atatggcatc actacaaaat ctatcagtcg
     7321 tagaaataca gttgtggagt ggtatagcga ttgctgctcc agctgtaacg acgatgatag
     7381 cttcgccgat atgggggaag ctaggtgata agatcagccg aaaatggatg gtcttaagag
     7441 cgttacttgg tttggcggta tgcttatttt taatggcatt gtgtacgaca ccattacagt
     7501 ttgtacttgt gaggttattg cagggactat ttggtggtgg tgttgatgca tcaagtgcgt
     7561 ttgcgagtgc agaggcgcca gctgaagatc gtggaaaggt attaggaaga ctgcaaagtt
     7621 cagtcagcgc agggtctctt gtggggccat taattggcgg tgttacagct tcgatattag
     7681 gttttagtgc gttactgatg agtattgccg ttattacttt tattgtctgt attttcggtg
     7741 cattaaaatt gattgaaacg acacatatgc caaaatcaca aacaccaaat attaataaag
     7801 gtattcgccg ttcatttcaa tgtctattat gcacacaaca aacatgtcga tttattatcg
     7861 ttggcgtttt agcaaacttt gctatgtatg gcatgctaac tgcattatca ccacttgctt
     7921 catcagtgaa tcatacagcg atagatgacc gtagtgtgat tggattttta cagtccgcat
     7981 tttggacggc ttcgatatta agcgcgcctt tatggggacg ctttaatgat aaatcatatg
     8041 ttaaatcagt atatatattt gccacgattg catgtggttg tagtgcgata ctgcaaggtt
     8101 tagcgacgaa tatagagttt ttaatggctg caagaatact tcaaggatta acatatagtg
     8161 cattgattca aagtgtcatg tttgttgtcg tgaatgcgtg tcatcaacaa cttaaaggca
     8221 catttgttgg aacgacgaac agtatgttag ttgttggtca aattattggc agtcttagtg
     8281 gcgctgccat tacaagttat actacaccag ctactacgtt tatcgttatg ggcgtagtat
     8341 ttgcagtaag tagtttattt ttaatttgtt caaccatcac taatcaaatc aacgatcaca
     8401 cattaatgaa attatgggag ttgaaacaaa aaagtgcaaa ataaagaatt aatacaacat
     8461 gcagcgtatg cggctatcga acgcatttta aatgaatatt ttagagaaga aaatttatat
     8521 caagtaccac ctcaaaatca tcaatggtct atacaattat cagagctcga aactttaacg
     8581 ggtgaatttc gctattggtc tgcgatgggg catcatatgt atcatccaga ggtatggctt
     8641 atcgatggaa aaagtaaaaa aataacaact tataaagaag caattgcgcg tattttgcaa
     8701 catatggctc aaagtgcaga taatcaaacg gcagtgcaac aacatatggc gcaaattatg
     8761 tctgacatcg ataatagcat tcatcgcacg gcgcgttatt tgcaaagtaa cacaatagac
     8821 tacgtagagg atcgttatat cgtttcagaa caatctttat acttaggtca tccatttcat
     8881 ccgactccta agagtgcaag tgggttttca gaagcagatt tagagaaata tgcacccgaa
     8941 tgtcatacat cattccaatt gcattattta gctgtgcatc aagatgttct gctcacgcgc
     9001 tatgtagaag gtaaagaaga tcaggttgag aaagtgttgt atcaattagc agacatagat
     9061 atatcagaga tacccaaaga ttttatttta ttaccaacac atccttatca aatcaatgtg
     9121 ttgcgacagc atccacagta tatgcaatat agtgaacaag gtttaataaa agaccttggc
     9181 gtttccggtg atttagtgta cccgacgtct tcggttagaa ctgtattttc aaaagcatta
     9241 aacatttatt taaaattacc gatacacgtt aaaattacta attttatacg tacgaatgat
     9301 cttgaacaaa ttgaacggac aattgatgcc gcgcaagtta tcgcatcagt caaagatgag
     9361 gttgaaacac cccattttaa attgatgttt gaagaaggat atcgtgcatt gttaccgaat
     9421 ccattagggc aaacagttga acctgaaatg gatttattaa caaatagtgc catgattgtt
     9481 cgtgaaggga taccgaatta ccatgctgat aaagatattc atgtattggc gtcattattt
     9541 gaaacgatgc ctgattcacc gatctctaag ttagcacaag tgattgagca aagtggttta
     9601 gcaccagaag catggcttga atgttatttg gatcgtacat tattgccgat attaaagttg
     9661 tttagtaaca caggcattag tctagaagca catgtacaaa atacattaat tgaattaaaa
     9721 gatggcatac ccgacgtatg ctttgtcaga gatcttgaag gcatttgtct atctagaacg
     9781 attgctactg aaaaacagct tgtgccaaat gttgtggcag catcaagccc tgttgtatat
     9841 gcacatgatg aagcatggca tcgtcttaaa tattatgttg tagtaaatca cttaggacat
     9901 ttagtatcaa ctattggtaa agcaactaga aatgaagttg tgttatggca acttgtagcg
     9961 catcgtctta tgacttggaa aaaagaatac gcgaataacg cagtatttgt tgactgtgta
    10021 gaagatttat atcaaacgcc gaccattgcg gctaaagcga atttgatgag taaattgaat
    10081 gattgtggtg caaaccctat ttatacacat ataccaaatc caatttgtta taacaaggag
    10141 gtatcgtatt gtgaatcaaa caattcttaa tcgtgtaaag actagagtaa tgcatcaact
    10201 ggtatcatca cttatttatg agaatattgt tgtgtataaa gcgtcatatc aagacggtgt
    10261 cggtcatttt acaatagaag gacatgattc agagtatcgt tttactgctg aaaagacaca
    10321 tagctttgat cgtatacgta tcacatcacc aattgagcgt gtcgtaggag atgaggcaga
    10381 tacaacaaca gactatacac aattattgag agaggctgta tttacatttc ctaaaaatga
    10441 tgaaaagcta gaacaattta ttgttgagtt attacagaca gaattaaaag atacacaaag
    10501 tatgcagtat cgagaatcaa acccaccagc aacacctgag acatttaacg actatgaatt
    10561 ttatgcgatg gaagggcatc agtatcatcc aagttacaaa tcacgtttag gatttacgtt
    10621 gagtgataat ttgaaatttg gtcctgattt tgtaccaaac gttaaactgc agtggttagc
    10681 tatcgacaaa gataaagtag aaacgacggt atcaagaaat gttgtagtta acgaaatgtt
    10741 acgtcaacaa gttggcgata agacttatga acattttgta cagcaaattg aagcgtctgg
    10801 caaacatgta aatgatgttg agatgatacc tgtacaccca tggcagtttg aacatgtcat
    10861 ccaagttgat ttggctgaag aaaggcttaa tggcacagta ctatggttag gggaaagtga
    10921 tgagctatat caccctcaac aatcgattcg tacgatgtcg ccaatagaca cgacaaaata
    10981 ttatttaaag gtaccaataa gtataacgaa cacttcaacg aaacgagtgt tggcgcctca
    11041 tacaattgaa aatgcagcgc aaattacgga ttggttaaag cagatacagc aacaagatat
    11101 gtatttaaaa gatgaattaa agacagtttt tctaggggaa gtcttaggac agtcttattt
    11161 aaatacacaa ctttcgcctt ataaacaaac tcaagtttat ggtgcgttag gtgttatatg
    11221 gcgtgaaaat atatatcata tgttaatcga tgaagaggat gcgataccat ttaatgcact
    11281 ttatgcaagt gataaggatg gtttaccatt cattgaaaag tggattaaac aatatggttc
    11341 tgaagcttgg acaaagcaat ttttagctgt agcgattcgt ccaatgattc atatgcttta
    11401 ttatcacggt attgcctttg aatcgcatgc acaaaatatg atgctcattc atgaaaatgg
    11461 ttggcctaca cgtattgcct taaaagattt ccacgatggt gttcgtttta agcgtgagca
    11521 tttaagtgaa gcagcttcac acctgacatt aaagccaatg ccagaagcac ataaaaaagt
    11581 gaatagtaat tcatttattg aaacagatga cgaacgttta gtacgcgact ttttacatga
    11641 tgcatttttc tttattaata tcgccgaaat catcttattt attgaaaagc aatatggtat
    11701 cgatgagcag cgacaatggc aatgggttaa agacattatc gaggcgtatc aagaagcatt
    11761 tccagagttg aataactatc aacatttcga tttgtttgaa cctacgattc aagttgaaaa
    11821 gttaacgaca cgtcgattat taagtgactc cgagttaaga attcatcatg ttacaaatcc
    11881 attaggtgta ggaggtatca atgatgcaac aactatctct gaaacataga ttaaacaatg
    11941 gtgattcagt ttatggcatt tttaattcta taccggaccc attgatgatc gaggttatcg
    12001 cagcaagcgg gtatgacttt gttgtgattg atacagaaca cgtggcgatt aatgatgaga
    12061 cactagcgca tttaattcgt gcagctgaag cagcgcatat tataccaatt gtacgtgtca
    12121 ctgcagtgat agatagagat atcattaaag tgttagatat gggtgcgaga ggtattattg
    12181 tgccacacgt taaagatcgt gagacagttg agcatattgt gaaattaagt cgttattacc
    12241 cgcaaggatt aagaagtttg aatggtggtc gcatggcaag atttggacgt acaccattac
    12301 ttgatgcaat ggagatggct aatgagcata ttatggtgat tgccatgata gaagatgttg
    12361 aaggggttat ggccattgac gatatagctc aagtcgaagg tttagacatg atagtcgaag
    12421 gtgccgcaga tttatcgcag tcacttggca taccatggca aacgcgtgat gatcaagtaa
    12481 catcacatgt tcaacatatt tttgaggttg tgaatgcaca tggtaaacat ttttgtgcat
    12541 taccacgtga agatgaagat attgcaaaat ggcaggcaca aggtgtacaa acatttattt
    12601 taggtgatga tcgcggaaaa atatatcgcc atttaagtgc atctctagcg acgtctaaac
    12661 agaaagggga tgatggctaa tgcgtatagt tcaacctgtt attgaacaat taaaagcaca
    12721 atctcatcca gtttgtcatt atatctatga tttagtcgga ctggaacatc atttgcaaca
    12781 tattacatcg tcattgccga gtaattgtca aatgtactat gcaatgaaag caaatagtga
    12841 acgaacaatc ctagatacaa ttagtcagta tgttgaagga ttcgaagttg catctcaagg
    12901 tgaaatagca aaaggtcttg cttttaaacc agcaaatcat attatttttg gtggccctgg
    12961 taagacagac gaggaactaa gatatgcagt aagtgaaggt gttcagcgta ttcatgttga
    13021 aagtatgcat gaattacaac ggctaaatgc catcttagaa gatgaagata agacacaaca
    13081 cattttattg cgtgttaatt tagcaggacc atttcccaat gcaacgttgc atatggcagg
    13141 acgcccaaca caatttggta tttctgaaga cgaagttgat gatgtcattg aagctgcgct
    13201 agtaatgcca aatattcatc tagatggctt tcattttcat tctatttcta acaatttaga
    13261 ctcgaattta catgtcgatg tagtgaaact ttattttaaa aaagcaaaat catggtctga
    13321 aaaacatcga tttccactca aacatatcaa tcttggtggt ggcataggcg ttaactatgc
    13381 agatttaact agccaatttg agtgggataa ttttgtagaa aattttaaaa cacttatcgt
    13441 tgagcaagaa atggaagatg tgacattgaa ctttgaatgt gggcgcttta ttgtggcaca
    13501 tattggttac tatgtgacag aagtgctaga tattaagaaa gtgcatggtg cttggtatgc
    13561 cattttaaga ggaggtacgc aacaatttag actgccggta tcttggcagc ataaccatcc
    13621 ttttgaaatt tatcgttata aggacaatcc atattcattt gaaaaagttt caatttcgag
    13681 acaggacaca acgttagtcg gtcaattatg tacaccgaaa gatgtctttg ctagagaagt
    13741 acagatagac gcaatcagta caggcgacgt tattgttttc aaatatgcag gtgcatacgg
    13801 atggtctatt tcacatcacg atttcttaag ccatccacat cctgaattta tttatttaac
    13861 gcaaacaaag gaggatgaat aactattgaa tcatattcat gaacatttaa aattggtacc
    13921 agtagataag attgatcttc acgaaacatt cgaaccttta agattggaaa aaacgaaaag
    13981 tagtattgaa gcagatgatt ttatacgtca tcctatttta gtgacagcga tgcaacatgg
    14041 tagatatatg gttatagatg gtgtgcatcg gtatacaagt ttgaaagcgt taggatgtaa
    14101 gaaagttcca gtgcaagaaa tccatgaaac acaatattca attagtacat ggcaacataa
    14161 agttccattt ggtgtgtggt gggaaacgtt acaacaagaa catcgcttgc catggactac
    14221 tgagacaaga caagaagcgc catttattac gatgtgtcat ggtgatacag aacaatattt
    14281 gtatacgaaa gatttaggcg aagcacattt tcaagtatgg gaaaaggttg tcgcaagtta
    14341 tagtggttgt tgttctgtag agagaattgc acaaggtaca tatccttgtc tttctcaaca
    14401 agatgtactc atgaagtatc agccattgag ttataaggaa attgaagcgg ttgttcataa
    14461 aggggaaact gtgccagcag gtgtgacacg ctttaatatt tcaggacgat gtcttaatct
    14521 tcaagtacca ctggcattac ttaaacaaga tgatgatgtt gaacaactgc gtaattggaa
    14581 gcagttttta gcagataagt ttgccaatat gagatgctat actgaaaaag tatacttggt
    14641 ggagcaatag ttttactgtg atgttgaggg aaatatgatg atttagcgta ttgatagcga
    14701 aaatataata aaacaatata gtgtggagaa cttttgatat tttataaata ttgaagttct
    14761 ccatttttgt attttgcata taaaaattaa ataaaataag gtatattaag gtaaagtata
    14821 aatattaaat aaatggggaa tagacatgga aaaaaatgta gaaaaatcat tcataaagat
    14881 aggtttatat tttcaaatag cttatatagt actcatggct ataactttat gtgggtttgt
    14941 aatttgctat ggactaattt tcggcctttt ctatttatta tcaggtagca gagctgatta
    15001 tttaatagta acaatagtta tatcggcaat aatttctata tttgtaatta tactttcaat
    15061 cgtacctgtc atcgtattgg catctgactt atttaaagaa aggatttcaa aaggtgtcat
    15121 attaattgta ttggctatta ttgctttagt attatgcaac tttgtatctg caatactctg
    15181 gtttgtttca gccatatcta ttttaggtag aaaaaaatta gtagctgcag cagatactac
    15241 cactattcaa aaaagtaaag ggaacgcaaa tcaagcatca cataaagaca cgtgtaaaaa
    15301 ggaacttgat agtcaagaca tgatggaaca tcctgaggtt aaaaatccca cgactaaaaa
    15361 ccttgaagga tttaacgaag aaatacataa agatgaagct acaactaaag ttgtcagtga
    15421 taacacggaa ccgccgattg aatcaaaagg ccatgtctcg aaaaaagatt gatgacaaac
    15481 taatcgagag acttaaaaaa ataatattca acataagaac ttttaaaacg acatttaaac
    15541 gcattgccaa tcactaatgg tagtgcgttt aactatacct taaatatctg aatattttgt
    15601 taaatggagc tacctttgtt gtactattca aatgaagagg agtaaaatgt aattaaagga
    15661 aagaaatttg aggagtgatc tttatgacaa acaacaaagt agcattagta actggcggag
    15721 cacaagggat tggttttaaa attgcagaac gtttagtgga agatggtttc aaagtagcag
    15781 ttgttgattt caatgaagaa ggggcaaaag cagctgcact taaattatca agtgatggta
    15841 caaaagctat tgctatcaaa gcagatgtat caaaccgtga tgatgtattt aacgcagtaa
    15901 gacaaactgc cgcgcaattt ggcgatttcc atgtcatggt taacaatgcc ggccttggac
    15961 caacaacacc aatcgataca attactgaag aacagtttaa aacagtatat ggcgtgaacg
    16021 ttgcaggtgt gctatggggt attcaagccg cacatgaaca atttaaaaaa ttcaatcatg
    16081 gcggtaaaat tatcaatgca acatctcaag caggcgttga gggtaaccca ggcttgtctt
    16141 tatattgcag tacaaaattc gcagtgcgag gtttaacaca agtagccgca caagatttag
    16201 cgtctgaagg tattactgtg aatgcattcg cacctggtat cgttcaaaca ccaatgatgg
    16261 aaagtatcgc agtggcaaca gccgaagaag caggtaaacc tgaagcatgg ggttgggaac
    16321 aatttacaag tcagattgct ttgggcagag tttctcaacc agaagatgtt tcaaatgtag
    16381 tgagcttctt agctggtaaa gactctgatt acattactgg acaaacaatt attgtagatg
    16441 gtggtatgag attccgttaa taatcatgca ttagcgataa ataaatcctt attgttaagt
    16501 ttaatcactt agcagtaagg attttttagt gcacttagaa gggattgtat tggtagaaaa
    16561 ttaataagcg aagttcttaa atgagttatg atgtcacagt ctaatgcatc agttgaaagc
    16621 attactagta ttaacacacc caagatatta taaaacatca caaaaacacc actatctaat
    16681 ttatctcaat aaaaattcac aaagttatct cattttattt ttataaataa aaaatatcga
    16741 taaaaagctt acaatacttt atgtttttat gatatatttt taatgtataa atgaggtgga
    16801 agatttggaa agagttttga taactggtgg ggctggtttt attgggtcgc atttagtaga
    16861 tgatttacaa caagattatg atgtttatgt tctagataac tatagaacag gtaaacgaga
    16921 aaatattaaa agtttggctg acgatcatgt gtttgaatta gatattcgtg aatatgatgc
    16981 agttgaacaa atcatgaaga catatcaatt tgattatgtt attcatttag cagcattagt
    17041 tagtgttgct gagtcggttg agaaacctat cttatctcaa gaaataaacg tcgtagcaac
    17101 attaagattg ttagaaatca ttaaaaaata taatagtcat ataaaacgtt ttatctttgc
    17161 ttcgtcagca gctgtttatg gtgatcttcc tgatttgcct aaaagtgatc aatcattaat
    17221 cttaccatta tcaccatatg caatagataa atattacggc gaacggacga cattaaatta
    17281 ttgctcgtta tataacatac caacagcggt tgttaaattt tttaatgtat ttgggccaag
    17341 acaggatcct aagtcacaat attcaggtgt tatttcaaag atgttcgatt catttgagca
    17401 taacaagcca tttacatttt ttggtgacgg actgcaaact agagattttg tatatgtata
    17461 tgatgttgtt caatctgtac gcttaattat ggaacacaaa gatgcaattg gacacggtta
    17521 taacattggt acaggcactt ttactaattt attagaggtt tatcgtatta ttggtgaatt
    17581 atatggaaaa tcagtcgagc atgaatttaa agaagcacga aaaggagata ttaagcattc
    17641 ttatgcagat atttctaact taaaggcatt aggatttgtt cctaaatata cagtagaaac
    17701 aggtttaaag gattacttta attttgaggt agataatatt gaagaagtta cagctaaaga
    17761 agtggaaatg tcgtgaaaat gacattgaag ctgtccataa taataagggt tatgcctatc
    17821 aaagaaaatt agatgcactc gaagaagtga gaaaaggcta ttacccaatt aaacgtgcga
    17881 ttgacttagt attaagtatc gttttattat ttttaacatt tccgattatg ttcatattcg
    17941 ccattgctat cgtcatagat tcgccaggaa accctattta tagtcaggtt agagttggga
    18001 agatgggtaa attaattaaa atatacaaat tacgttcgat gtgtaaaaac gcagagaaaa
    18061 atggtgcgca atgggctgat aaagatgatg atcgtataac aaatgtcggg aagtttattc
    18121 gtaaaacacg cattgatgaa ttaccacaac taattaatgt tgttaaaggg gaaatgagtt
    18181 ttattggacc acgcccggaa cgtccggaat ttgtagaatt atttagttca gaagtgatag
    18241 gtttcgagca aagatgtctt gttacaccag ggttaacagg acttgcgcaa attcaaggtg
    18301 gatatgactt aacaccgcaa caaaaactga aatatgacat gaaatatata cataaaggta
    18361 gtttaatgat ggaactatat atatcaatta gaacattgat ggttgttatt acaggggaag
    18421 gctcaaggta gtcttaattt acttaataag ttcaaataaa agttatattt taaagattgt
    18481 gaccaattgt tacagtataa cgaggaatcc cttgagacag tatcaaatgg cattaagaaa
    18541 tatgtgccat cattgatttg catggctata aatactattc atctgatgag atagccatgt
    18601 taagaaattg aaagtatagc attaaagggg tttgtaacag ttgaaaatta tatattgtat
    18661 tactaaagca gacaatggtg gtgcacaaac acatctcatt caactcgcca accatttttg
    18721 cgtacaccat gatgtttatg tcattgtagg caatcatgga ccaatgattg aacaactaga
    18781 tgcaagagtt aatgtaatta ttctcgaaca tttagtaggt ccaattgact ttaaacaaga
    18841 tattttagct gtcaaagtgt tagcacagtt attctcgaaa attaagcctg atgttatcca
    18901 tttacattct tccaaagctg gaacggtcgg acgaattgcg aagttcattt cgaaatcgaa
    18961 agacacacgt gtagttttta ctgcgcatgg atgggctttt acagagggtg ttaaaccagc
    19021 taaaaaattt ctatatctag ttatcgaaaa attaatgtca tgtattacag atagcattat
    19081 ttgtgtttca gatttcgata aacagttagc gttaaaatat cgatttaatc gattgaaatt
    19141 aaccacagta cataatggta ttgcagatgt tcccgctgtt aagcaaacgc taaaaagcca
    19201 atcacataac aatattggcg aagtagttgg aatgttgcct aataaacaag atttacagat
    19261 taatgccccg acaaagcatc aatttgttat gattgcaaga tttgcttatc caaaattgcc
    19321 acaaaatcta atcgcggcaa tagagatatt gaaattacat aacagtaatc atgcgcattt
    19381 tacatttata ggcgatggac ctacattaaa tgattgtcag caacaagttg tacaagctgg
    19441 gttagaaaat gatgtcacat ttttgggcaa tgtcattaat gcgagtcatt tattatcaca
    19501 atacgatacg tttattttaa taagtaagca tgaaggtttg ccaattagca ttatagaagc
    19561 tatggctaca ggtttgcctg ttatagccag tcatgttggc ggtatttcag aattagtagc
    19621 tgataatggt atatgtatga tgaacaacca acccgaaact attgctaaag tcctggaaaa
    19681 atatttaata gacagtgatt acatcaaaat gagtaatcaa tctagaaaac gttatttaga
    19741 atgttttact gaggagaaaa tgattaaaga agtggaagac gtttataatg gaaaatcaac
    19801 acaatagtaa attactaaca ttgttactta tcggtttagc ggtttttatt cagcaatctt
    19861 cggttattgc cggtgtgaat gtttctatag ctgactttat cacattacta atattagttt
    19921 atttactgtt tttcgctaac catttattaa aggcaaatca ttttttacag tttttcatta
    19981 ttttgtatac atatcgtatg attattacgc tttgtttgct attttttgat gatttgatat
    20041 ttattacggt taaggaagtt cttgcatcta cagttaaata tgcatttgta gtcatttatt
    20101 tctatttagg gatgatcatc tttaagttag gtaatagcaa aaaagtgatc gttacctctt
    20161 atattataag cagtgtgact ataggtctat tttgtattat agctggtttg aacaagtccc
    20221 ctttactaat gaaattgtta tattttgatg aaatacgttc aaaaggatta atgaatgacc
    20281 ctaactattt cgcgatgaca cagattatta cattggtact tgcttacaag tatattcata
    20341 attacatatt caaggtcctt gcatgtggta ttttgctatg gtctttaact acaacggggt
    20401 ctaagactgc gtttatcata ttaatcgtct tagccattta tttctttatt aaaaagttat
    20461 ttagtagaaa tgcggtaagt gttgtgagta tgttagtgat tatgctgata ttactttgtt
    20521 ttacctttta taatatcaac tactatttat tccaattaag cgaccttgat gccgtaccgt
    20581 cattagatcg aatggcgtct atttttgaag agggctttgc atcattaaat gatagtgggt
    20641 ctgagcgaag tgttgtatgg ataaatgcca ttttagtaat taaatataca ctaggttttg
    20701 gtgtcggatt agtggattat gtacatattg gctcgcaaat taatggtatt ttacttgttg
    20761 cccataatac atatttgcag atctttgcgg aatggggcat tttattcggt gcattattta
    20821 tcatatttat gctttattta ctgtttgaat tatttagatt taacatttct gggaaaaatg
    20881 taacagcaat tgttgtaatg ttgacgatgc tgatttactt tttaacagta tcatttaata
    20941 actcaagata tgtcgctttt attttaggaa ttatcgtctt tattgttcaa tatgaaaaga
    21001 tggaaaggga tcgtaatgaa gagtgattca ctaaaagaaa atattattta tcaagggcta
    21061 taccaattga ttagaacgat gacaccactg attacaatac ccattatttc acgtgcattt
    21121 ggtcccagtg gtgtgggtat tgtttcattt tctttcaata tcgtgcaata ctttttgatg
    21181 attgcaagtg ttggcgttca gttatatttt aatagagtta tcgcgaagtc tgttaacgac
    21241 aaacggcaat tgtctcagca gttttgggat atctttgtca gtaaattatt tttagcgtta
    21301 acagtttttg cgatgtatat ggtcgtaatt actatattta ttgatgatta ctatcttatt
    21361 ttcctactac aaggaatcta tattataggt gcagcactcg atatttcatg gttttatgct
    21421 ggaactgaaa agtttaaaat tcctagcctc agtaatattg ttgcgtctgg tattgtatta
    21481 agtgtagttg ttatttttgt caaagatcaa tcagatttat cattgtatgt atttactatt
    21541 gctattgtga cggtattaaa ccaattacct ttgtttatct atttaaaacg atacattagc
    21601 tttgtttcgg ttaattggat acacgtctgg caattgtttc gttcgtcatt agcatactta
    21661 ttaccaaatg gacagctcaa cttatatact agtatttctt gcgttgttct tggtttagta
    21721 ggcacatacc aacaagttgg tatcttttct aacgcattta atattttaac ggtcgcaatc
    21781 ataatgatta atacatttga tcttgtaatg attccgcgta ttaccaaaat gtctatccag
    21841 caatcacata gtttaactaa aacgttagct aataatatga atattcaatt gatattaaca
    21901 atacctatgg tctttggttt aattgcaatt atgccatcat tttatttatg gttctttggt
    21961 gaggaattcg catcaactgt cccattgatg accattttag cgatacttgt attaatcatt
    22021 cctttaaata tgttgataag caggcaatat ttattaatag tgaataaaat aagattatat
    22081 aatgcgtcaa ttactattgg tgcggtaatg aatttagtat tatgtcttgt tttgatatat
    22141 ttttatggaa tttacggtgc ggctattgca cgtttaatta cagagtttat cttacttatt
    22201 tggcgatttg ttgatattac taaaatcaat gtgaagttga atattgtaag tacgattcaa
    22261 tgtgtcattg ctgccgttat gatgtttatt gtgcttggtg tggtcaatca ttatttgccc
    22321 cctacaatgt acgctacgct gctattaatt gcgattggta tagtagttta tcttttatta
    22381 atgatgacta tgaaaaatca atacgtatgg caaatattga ggcatcttcg acataaaaca
    22441 atttaagtat cggtaacgct atactttaga aatttaagat taagaagaaa aggcaatttc
    22501 ttattgaaaa atggaagttg tcttttttaa ttctctttaa aagcgggaaa caaaagcagt
    22561 taaatgcctt tttgcattca atattaaata ttatatcaat ttcgaatatt taaattttat
    22621 ataattggat ataacaaata aataataatt attgcaaaac acacccgaaa ttaattatta
    22681 taaaagtata ttcataaaag gaggaatata cttatggcat ttaaattacc aaatttacca
    22741 tatgcatatg atgcattgga accatatata gatcaaagaa caatggagtt tcatcacgac
    22801 aaacatcaca atacgtacgt gacgaaatta aacgcaacag ttgaaggaac agagttagag
    22861 catcaatcac tagcggatat gattgctaac ttagacaagg taccggaagc gatgaggatg
    22921 tcagtccgta ataatggcgg tggtcatttt aaccattcat tattctggga aatactatca
    22981 cctaattctg aagaaaaagg tggcgtaata gatgacatca aagcgcagtg gggcacttta
    23041 gatgaattta aaaatgaatt tgcaaataaa gcaacaacat tatttggatc aggttggact
    23101 tggttagttg ttaatgatgg aaaattagaa attgtgacaa cgccaaacca agataatcca
    23161 ttaacagaag gcaaaacacc aatcttacta tttgatgttt gggagcatgc ctactatctg
    23221 aaatatcaaa ataaacgtcc agactatatg actgcatttt ggaatattgt taactggaaa
    23281 aaagttgatg aattatacca agcagcaaaa taatataact taatataatt gaggtggagc
    23341 atttacaagg tgttccactt ttttgtactt aatatcttta cttatttgtt tttgtgtaat
    23401 gggatagcac gtaaaagtgg caaaataata agataaattt caactcgaaa taccttatta
    23461 ttgttgacta taatgatgac ctaaatgtta tatacatcag acaacactat taattaatca
    23521 acatattgac attaaataaa ttgacaaaat aagtaattat tgtgaatcta aagtgaaatt
    23581 tttataaaaa attgtaacga ttcaaaaatt ttgttgcatt tcttttgtaa tcatatgata
    23641 atgtaaatgt aatcaaattg taatataagg gaaaagacaa tgaaaaaatt agcaacagta
    23701 ggttctttaa ttgtaacaag cactttagta ttctcaagta tgccttttca aaatgcgcat
    23761 gccgacacga cttcaatgaa tgtgccgaat aaacaaagcc aaaatgtaca aaatcatcgc
    23821 ccttatggcg gagtagtacc acaaggaatg acacaagcac aatatactga attagagaaa
    23881 actttacccc aattaagcgc tggcagtaat atgcaagact ataatatgaa attgtatgat
    23941 gcgacgcaaa atattgctga taaatacaat gtgataatta caactaatgt aggggtattt
    24001 aaaccacatg ctgttagaga tatgaatggc catgcgttac ctttaacaaa agatggcaat
    24061 ttttatcaaa cgaatgtaga tgcaaatggt gttaatcatg gtggtagtga aatggtgcaa
    24121 aataaaacag gtcatatgag tcaacaagac catatgaatc agaacacaca catgaaccaa
    24181 cagccacaaa tacaacaagg tcatatgcaa tcatcaaacc atcaaatgat gagtccaaaa
    24241 gcaaatatgc attcatcaaa tcatcaaatg aaccaaagta acaaaaaagt tttaccagct
    24301 gctggtgaaa gtatgacatc aagtattctt actgcaagta ttgccgcact actattagta
    24361 tctgggttat tcttagcatt tagacgacgt tcaacaaata aataaacata atacgattaa
    24421 taatagaaaa atcgtgtgat tatctgagcg agcctaggac ataaatcaat gtcctaggct
    24481 cgctaatgtt atattggcag tagttgactg aatgaaattg cgcttgtaac aagcttttcc
    24541 atttcttacc aactccctaa atagtcatca aaaaatttct tatattttaa taattttaat
    24601 aatccgattg tcttatacgt gtcagtgtta attcagatat ttcctgtgga atataccact
    24661 tattaatcat aattggataa ggtgtttgtg cgtacagtgt ttcaataatc agccaacaat
    24721 gtgtatcacc atcaaacacg tgactatgat ttttgaagcg gggcgctttg gtaatagaca
    24781 tttttaaatc tgattgatat gcattgctat aaatcgtttg ctcaacgaat gtcttcatgt
    24841 cgtcttcgtt ttgtgtattc actttaaatg tgtcaatgac atttaacggt ataaaggtaa
    24901 agcaaaatgc atcagcttgc ttagaatgat tgtccttttt ttgataatag cgttccattg
    24961 caatgacggc agaaggatgg tttgcaaaca aatgatttgt atattcactt tctaaatcaa
    25021 cacgataatt aattgatgac atagatacgc gagctagcaa tatttgatca agtggatgct
    25081 taaattgatc catacttgaa gcgtgttggg catttgtttg tggaataaca aagtgtccct
    25141 tccctcttgt actctctacg atgccatctt cggctaacaa ttttatagct tggcgcaaag
    25201 tcatacgact gacatcaaag cgcgcacaaa gttccttttc agtaggtaat gcatggccac
    25261 tcggatattt tcctatttga atttctttat ataacgtatt ataaatcgtt aaaaattttg
    25321 gttgtgtttg cgtcacgtag acaacctcca taaagttact taatcactct catcatacaa
    25381 taatttttac tcgaattgga aaaattataa aaattaaata tagataggct ttgaaaatta
    25441 gttttataca aggttagtag ctgtaactgt aaaatgttct taatattgtc aaaatgtaat
    25501 gcttgaaagc gcttttaaaa aatattatta tatacatgat tagacaaata gacaaatcac
    25561 tatacaaata ttgggaggaa tattttatga aatcaacacc acacattaaa ccaatgaatg
    25621 acgtcgaaat tgcagaaacg gttctattgc caggagatcc gttaagagct aagttcattg
    25681 cagaaactta tttggatgat gtggaacagt tcaatacagt gcgaaacatg tttggtttta
    25741 ccggaacata taaaggtaaa aaagtttctg tcatgggttc aggtatgggt atgccatcta
    25801 ttggcattta ctcttatgaa ttaattcata catttggttg taaaaaatta attcgcgttg
    25861 gctcttgtgg cgcgatgcaa gaaaacattg atttatatga tgtgattatt gcacaaggtg
    25921 cctctactga ttcaaattac gttcaacaat atcaattacc aggtcatttt gcgccaattg
    25981 cttcttatca attattagaa aaagcagttg aaacagcacg tgacaaaggt gtacgtcatc
    26041 atgtaggtaa tgtgttatca agtgatattt tctataacgc ggatacaaca gcgagtgaac
    26101 gttggatgcg tatgggtatt ttaggtgtag aaatggaatc agctgcatta tacatgaatg
    26161 caatttacgc tggtgtcgaa gcattaggtg tgttcacagt gagcgatcat ttaattcatg
    26221 aaacgtcaac aacacctgag gaaagggaac gtgcatttac agatatgatt gaaattgcac
    26281 tgtcattggt gtagatgatt atgaatgttg aatattctaa aataaagaaa gcagtaccta
    26341 ttttattatt cttatttgta ttcagtttgg ttatagacaa ctcatttaaa ttgatttctg
    26401 tagccattgc tgatgactta aacatatctg taacgacagt aagttggcaa gcgacattag
    26461 ccggtttagt aattggtatt ggcgctgtag tatacgcttc attatctgat gccattagta
    26521 tacgcacact atttatttat ggcgtgatat taatcattat cggatcaatt attggttaca
    26581 ttttccaaca tcaattccca ttacttttag ttggacgtat tattcaaact gccggtttag
    26641 ctgctgcaga gacattatat gtgatatatg ttgcaaagta tctttctaaa gaggaccaga
    26701 agacttacct tggcttaagt acgagcagtt attccttgtc attagttatc ggtacattat
    26761 caggtggatt tatttctacg tatttacact ggacaaatat gtttttaatt gcattaatcg
    26821 tagtatttac gttgccattc ctatttaaat tattaccaaa agaaaataat acgaataaag
    26881 ctcatttaga ttttgttggc ttaattctag tggcaactat tgctacaaca gtcatgctgt
    26941 ttattacgaa ctttaattgg ttatatatga ttggtgcctt aattgcgatt atcgtttttg
    27001 cgctatatat taaaaatgcg caacgtccat tagtaaataa atcatttttc caaaataaac
    27061 gttatgcttc atttttattt atagtatttg taatgtatgc tatccaattg ggttatattt
    27121 ttacgttccc attcataatg gagcaaattt atcatctgca actagacaca acatcactgt
    27181 tattagtacc gggttatata gtagcagtca ttgttggtgc attaagtggt aaaatcggcg
    27241 aatatctgaa ttcaaaacaa gcgattatca cagcaattat tttaatagca ctgagcttga
    27301 ttttacctgc atttgcagta ggtaatcaca tttcaatctt cgtcatttct atgatattct
    27361 ttgcaggtag ctttgcttta atgtatgcac ctttacttaa cgaagccatt aaaacaatag
    27421 atcttaatat gacaggtgtg gctattggtt tttataattt aattattaat gtggcggtat
    27481 ctgtaggtat tgcgattgct gcggctctaa tcgattttaa agcattaaat ttcccaggca
    27541 atgatgcatt aagttcacat ttcggtatta ttttaattat tttaggttta atgagtattg
    27601 tcggattagt tttattcgtc atcttaaatc gttggacaca atctgaaaaa taaatagata
    27661 taaattcgcg agatatattc gtatttatag taaaattaaa taaagagatt atataacacg
    27721 aggagtagta agtatgaaat ttgagaaata tatagatcac actttattga agcctgagtc
    27781 aacacgtacg caaatcgatc aaatcatcga tgaagcgaaa gcatacaatt ttaaatctgt
    27841 atgtgtgaat ccaacgcatg ttaaatatgc agcagagcga ctagctgatt cagaggtgct
    27901 cgtttgtacg gtaataggat tcccattagg tgcgtcgaca actgcaacga aagcatttga
    27961 aacagaagat gcaattcaaa atggtgcaga tgaaattgac atggtcatca acatcggcgc
    28021 attaaaagat ggacgttttg atgatgtaca acaagacatt gaagcagtgg ttaaagctgc
    28081 gaaaggtcac acagtaaaag tgattattga gacggtattg ttggaccatg acgaaattgt
    28141 aaaagcgagt gaattaacaa aagcggctgg tgcggacttc gttaaaactt caacaggttt
    28201 tgcaggtggc ggtgcgactg cagaagacgt taaattaatg aaagatacag taggtgctga
    28261 tgtagaagta aaagcatcag gtggcgtacg taatttagaa gatttcaata aaatggttga
    28321 agcaggtgcg acacgtattg gtgcgagcgc aggcgttcaa attatgcaag gtttagaagc
    28381 agattcagat tactaatata tataaaattt gggagtgata gctatgacaa gaccatttaa
    28441 tcgtgtacat ttaatcgtaa tggattcagt aggtattggt gaagcgccag acgcagctga
    28501 ttttaaagat gaaggttcac atactttaag acatacctta gaaggtttcg atcaaacttt
    28561 accaaacctt gaaaagttag gtctagggaa catcgataaa ttaccagtag taaatgcagt
    28621 tgaacaacca gaagcatact atactaaatt gagtgaagct tcagttggta aagatacaat
    28681 gactggtcac tgggaaatta tgggattaaa tattatgcaa ccttttaaag tataccctaa
    28741 tggattccct gaagagttaa ttcaacaaat tgaagaaatg acaggtcgta aagttgttgc
    28801 taacaaaccg gcatcgggta cgcaaattat cgatgagtgg ggcgagcacc aaatgaaaac
    28861 tggtgactta attgtttata caagtgcaga cccagtattg caaattgctg cacatgaaga
    28921 cattatccca ttagaagagt tatatgatat ttgtgaaaag gttcgtgagt tgacaaaaga
    28981 ccctaaatat ttaattggtc gtattatcgc acgtccatat gttggtgaac caggaaactt
    29041 tacacgtaca tctaatcgac atgactatgc gttaaaacca tttggtaaaa ctgtcttaga
    29101 tcatttgaaa gacggtggtt atgatgttat tgccatcggt aaaattaatg acatttatga
    29161 tggtgaaggt gtaacagaag cggttcgtac gaagagtaac atggacggta tggatcaatt
    29221 gatgaaaatt gttaagaaag atttcacagg tattagcttc ttaaacttag tagactttga
    29281 tgcattatac ggtcatcgtc gtgataaacc aggttatgca caagcaatta aagatttcga
    29341 tgatcgcttg ccagaactgt ttagcaactt aaaagaagac gatttagtaa ttattacagc
    29401 agaccatggt aatgacccga cagcgccagg tacggaccat acgagagaat atatcccagt
    29461 aattatgtac agtccgaaat ttaaaggtgg tcatgcacta gaaagtgata ctacattcag
    29521 ttctatcggt gcaactatag cagataattt caacgtaaca ttaccagagt tcggtaaaag
    29581 ttatttaaag gaattgaaat agaataaatt tagatattat aaaaacagca gtgaagttaa
    29641 ctataacaat agttttcttc actgctgttt ttattataat agagaaacgt gacggtagga
    29701 cctcttattt aggagtatcc tgatttaatg ttaaacaata cgttttcgga ttgaaccgga
    29761 aattaaatcg acaattgcga ccattagtac taaaccgatt aatataatac ctacacggtc
    29821 ccaagaacgt gtttgaatgg caaatatgag tggtgtcccg ataccaccag ccccaattag
    29881 ccccagtata gaagctgaac gtaagtttag ttcaaagcga taaagtatga gtgatagaaa
    29941 ggcaggcata atttgtggta tgactgcaaa tacgagtgtt ttaatcttat tcgcaccact
    30001 ggcctttaat gattctacag cactgaaatc tagaccttca atatcttcag ctaaaagttt
    30061 cccaagcata cctacagaat ggatacctaa agctaataca cctgaaaatg aacctgggcc
    30121 aacagctttg ataaatataa gtgccattac aatttctggg aagacacgta taacacttaa
    30181 aataaatttg ctaacacctg aaaccgggcg taactttacc atattatttg cacctaaaaa
    30241 tgctaatgga atacagataa ttgcggcgat gaaagtacct acaacggcta tcgcaaaggt
    30301 ttcaagtaaa ccacgtaata agtcttcgcc atctggtata tagatatagc tgatgtcagg
    30361 atggaataat ccgctgaata tggattttaa gatttctaat gatttacttt taagttctaa
    30421 acttggtaca cctgcaaatg cccagatgat aatagctaag acgacaattg caataagcca
    30481 tcttttaatc aattttcgtt tgtgtgcttt tgtgtgaaca ttatattttg ctatttcctg
    30541 tgtcatgcga gatgtgccct cactttcgta ctgatgtaat caatgacgac gacgataact
    30601 aaagtaaata aaataatcgt tgctgttttt ggatattgaa ataaaccaag tgtttgatca
    30661 taaaacaatc caataccgcc agcgccgact aatccaagca cagctgaagc tcgtatattt
    30721 acttcaaatg catataatac gtatgacata aatgacgata tggcttgtgg tacaacaccg
    30781 aaaacaatcc attttatttt attagcgcca acagccgtca ttgcttccat tggacctgga
    30841 tctatcgttt ccaatgattc atataataat tttccaataa tacagatagt taaaataaac
    30901 aatgctaata tccctggaat ttgaccgatt ccaaatacag ccacaaagat tgctgctaat
    30961 aacaaatctg gaatagtacg aactatattt aaaataaagc gcgagggtat tgaaatccac
    31021 ttttgatgaa cgatattgct agcacataat aacgcaattg gtattgaaac gatgctacct
    31081 aatactgtac ttacgatagc cattcgaatg gtatctaaca ttggcgttgt aatttgttgt
    31141 aaatactcga aatcaggtgg aatcatttgt ttgaatagat cacctatttg aggtattcct
    31201 atcattaaat ctccaaaatt aaaccccgta taaatgaagc tccaaatgat aagcacaatg
    31261 attaacatga aggtaaaact cgtttttaaa gaaacctttt tctttaaaag ggagtcatac
    31321 tttgtaggta tttctaaagg catgttagtt cactcctagc ttttcatctt ctttaattgt
    31381 acgtccatat atttcactaa atacgtcatc tgttgcttca gatgcaggac catcatagac
    31441 aacttcacca tcacgtaaac caatgatgcg tgtgccatat tcttttgcca agtcaacaaa
    31501 atgtaaatta attaaaattg tgatgcctaa ttcttggttg atttttctta aatcatccat
    31561 aacctgtttc gttgttaatg ggtctaatga agcaactggt tcatctgcaa gaataatttc
    31621 ggattcttgg catagcgcac gtgcaataga tatacgttgt tgttggccac ctgataattc
    31681 atcagagcgt tgattatatt tatctaagat attgacgcgt tctagtgcat ccattgcttt
    31741 aattttgtct tcttttggga ataaacctaa taccattttc caagtagggt gataacctac
    31801 acgtccactt agtacatttc gtaatacact tgaccgttta actaaattaa aatgttggaa
    31861 aatcatacct atatttcggc gcatttctaa taatgcttta ccatgggctt tagtgatgga
    31921 tttgccttgg atgaaaattt cacctgacgt gatatcatgc aaacgattta cagatcttaa
    31981 taacgtggat ttcccagcac cagatagtcc gacaataact gcaaattcac ctttttcaat
    32041 atttaagtta atatttttca agcctacatg accgttagga tagactttac tgacgttttt
    32101 aaattcgatt tgactcatgt ttgacacctt tctttaataa agaaaagcca aggtaaactg
    32161 aaatatcata gacattgggt ttctgtgtac aaatggtttc aaatgtacag cgacaccttt
    32221 ctatatctgt ttcagtttag cgcctagctt ttcaatattt atctagaata tatctattga
    32281 acgaaagctt ttaataccaa attcgataat gattatttca tatctttaac taatttttcg
    32341 tactctctta caatgtcgaa atttgaatct ttcgtttctg tgtatccttc atgtgaataa
    32401 acttcgctaa taattttgtg accttctttt gatttagcaa tgtctataaa agcttttttc
    32461 aatttttctt ggaaatcttt atccatatct ggtcttacag aaattgtgtc attcggaata
    32521 gcttgtgtta attttaaaat tcgtgtgtct ttaaatacat ttggttggtc ttttttcaca
    32581 gtattacgtg catcgttaaa tacagccgca gcatctacat ctccatttaa taatgagata
    32641 actgcttggt catgaccttt aacattcaca attttcatat ctttagttgc attaatacct
    32701 gcttcgtttt ttaacatcgc aagtgggaat gtatatccag cagttgatgt tacatcttgt
    32761 aaggcaattt tcttaccttt taaatctttc aagcttttaa tttttgagtc ttttttaaca
    32821 agaatttctg atttataact atctacaagt tctttacttg ctgaaccatc ttcttttaca
    32881 ccaaaacgtt gtgcttgtaa taataaatca gctgcttttt gatcatgtgc taatgtgtat
    32941 gccgttggtg gtaagaaacc aacatcaact tttttagact tcatagcttc aacaattgta
    33001 ttgtagttag ttgatacaga cactttaact ggaattccta attctttaga tagtaatttt
    33061 tctaatggtt ttgctttagc ctctaatgtt ccagcatttt gcgaaggtac aaattgtact
    33121 gttaattctt taggtttgta tcctcctgat ttagaatccg aatcattact agcgttcttt
    33181 tgattatcta aagaacttga gtttccacat gctgctgcaa aaacaatgac tgctaacatt
    33241 aatacaaata aatacttaaa atttttcatt tgataactgt ccccttcaca ttcttaatcg
    33301 tgtaatatgt atgcaatgaa attacactta tagcgtacca catttaaatg tgaaaaagta
    33361 ttttataaaa atgaatttta ataactttct ttaagagttt gataagattt tgtaaacttt
    33421 tcgttaaatt gctcatatgc aacgaatttt tatcctataa ttcaagaaca aatttatttt
    33481 aaaaggagcc tcacaaaatg aaaaaaatat ataagtcatt aactgtctct gcaattgttg
    33541 caacggtatc attaagtgct ttaccgcaat ctttagctat aacgcatgaa tcgcaaccta
    33601 caaagcaaca gcgaacggta ttattcgatc gttctcatgg tcaaacagct ggtgttgcag
    33661 attgggttag tgatggtgca ttttcagatt atgcggattc aatacaaaaa caaggttatg
    33721 acgttaaagc tattgatggt cattcgaaca taacagaagc aagtttgaaa agttccaaaa
    33781 tatttgtaat tcctgaggct aacattcctt tcaaagaatc agaacaggca gcaattgtta
    33841 actatgtgaa acaaggtggc aatgttgtct ttatttcaga tcattacaat gctgaccgaa
    33901 atttaaatcg tattgattca tcggaggcaa tgaatggtta tcgacgtgga gcatatgaag
    33961 atatgtcgaa aggtatgaat gcagaagaaa aaagctctac tgcaatgcaa ggtgtgaaaa
    34021 gttcagattg gttatctaca aactttggcg tacgttttcg atataatgca ctaggtgatt
    34081 taaatacgag caatattgtt tcttcaaaag aaagtttcgg tattactgaa ggtgtgaaat
    34141 ctgtctctat gcatgccgga tcgacattag caattactaa tccagagaaa gcaaaaggta
    34201 ttgtgtatac accagaacaa ttgccagcga aaagtaaatg gtcacatgct gtagatcaag
    34261 gtatttataa tggtggcggt aaagcagaag gcccctatgt agcaatttct aaagttggaa
    34321 aaggtaaagc agcatttatc ggtgattcat cacttgtgga agatagttcg cccaaatatg
    34381 taagagaaga taatggagaa aagaagaaaa catatgatgg ttttaaagaa caagacaacg
    34441 gtaagctatt aaataatata acggcttgga tgtctaaaga tagtgatggg aaatcactta
    34501 aggcgagtgg actaacatta gatacaaaga ctaagttgct tgattttgaa cgaccagagc
    34561 gttcaactga gcctgaaaaa gagccatggt cacaaccgcc gagtggttat aaatggtatg
    34621 acccaacaac atttaaagca ggtagttatg gcagtgaaaa aggcgcggat cctcagccaa
    34681 acacaccaga tgatcatacg ccaccaaatc agaacgtaaa aatatcattt gatatcccgc
    34741 aaaatgtttc tgtaaatgag ccatttgaag tgacaataca tttaaaagga tttgaagcaa
    34801 atcaaacact tgaaaatctt agagttggta tttacaaaga aggcggacgt caaatcggac
    34861 aattttcaag taaagataac gattataacc caccaggtta cagtactttg ccaacagtta
    34921 aagcagatga aaacggaaat gctacaatta agatcaatgc taaagtactt gaaagtatgg
    34981 aaggttcaaa gattcgttta aaactcggtg acaaaacctt gattacaaca gacttcaaat
    35041 aaatatataa tagaaataag aaagatgttt gtgattgaag gagtgagtga ggatgtcaaa
    35101 catagcattt tatgtcgtga gcgacgtaca tggttatatt ttcccaacag attttacgag
    35161 tagaaatcaa tatcaaccta tgggattgtt actagcgaat catgttatag aacaagacag
    35221 aaggcagtat gaccaaagtt ttaaaataga taatggtgat tttttgcaag ggtcaccatt
    35281 ttgtaattac ttaatcgcgc atagcggcag tagccagcct ttagttgatt tttataatca
    35341 aatggcattc gactttggta cgcttggtaa tcatgaattt aattatggat tgccatactt
    35401 aaaagacact ttacgcagac tcaattatcc agttttgtgc gctaatattt atgaaaatga
    35461 tagtacattg actgataacg gtgtgcagta ttttcaggtt ggagatcaaa cggttggtgt
    35521 gataggttta acgacacaat ttattcccca ttgggaacaa ccagagcata ttcagtcact
    35581 tacgtttcat agtgcttttg aaacacttca acaacactta cctgaaatga agcgacatgc
    35641 agatatcatt gtggtttgtt accatggtgg atttgaaaag gatttagaaa atggtacgcc
    35701 gaccgaagta ttaacgggtg aaaatgaagg atatgccatg ttagaagcgt tttctaaaga
    35761 tatagatatc tttattacgg gtcaccaaca tcgacaaatt gctgaaagat ttaagcaaac
    35821 ggctgtgatt caacctggta cgagaggtac aactgtaggc aaagttgtct tgagtactga
    35881 tgaatatgaa aatgtatccg ttgaatcatg tgaattactt cctgttatag atgattccac
    35941 atttactatt gatgaagatg accaacattt acgaaagcag ttagaggact ggttagatta
    36001 cgaaattact acattgccat atgatatgac gattaatcat gcatttgagg cacgtgtggc
    36061 accgcatcct tttactaatt ttatgaatta cgctttatta gaaaaaagtg acgcagatgt
    36121 tgcctgtaca gctttgtttg attctgctag tggtttcaag caagtcgtga cgatgcgaga
    36181 tgttattaac aattacccat ttccaaatac atttaaagtt ttagctgtaa gtggtgccaa
    36241 acttaaagaa gccattgaac gatcagcaga atattttgac gtgcaaaatg atgaagtaag
    36301 tgtgagcgca gacttccttg gacccaaacc acaacacttt aattatgata tatatggtgg
    36361 cgtaagttat accattcatg ttggaagacc aaagggacaa cgtgtgagca atatgatgat
    36421 tcaaggtcac gcagttgatt taaagcagac atatacaatt tgtgtaaata attatcgtgc
    36481 agttggcggt ggtcagtatg atatgtttat cgacgcgcca gttgtgaaag atattcaagt
    36541 tgaaggcgca caattactta ttgatttttt atcaaataat aatttgatgc gtatcccgca
    36601 agttgttgat tttaaagttg aaaagtgacg gatatatgaa aaacttactt gattttaatc
    36661 gggtaagttt ttgtttttgt ttaaactaac cactctta
//
LOCUS       DAPDIM010000026        36384 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000026 DAPDIM010000000
VERSION     DAPDIM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 36384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36384
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.026"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            237..32111
                     /gene="ebh"
                     /locus_tag="RFE25_001330"
     CDS             237..32111
                     /gene="ebh"
                     /locus_tag="RFE25_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001635093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyperosmolarity resistance protein Ebh"
                     /protein_id="HDU2816401.1"
                     /translation="MNYRDKIQKFSIRKYTVGTFSTVIATLVFLGFNTSQAHAAETNQ
                     PASVVKQKQQSNNEQTENRESQVQNSQNSQNSQSLSATHENEQPNNSQANLVNQKVAQ
                     SSTTNDEQPASQNVNTKKDSATAATTQPDKEESKHKQNESQSANKNGNDNRAAHVENH
                     EANVVTASDSSDNGNVQHDRNELQAFFDANYHDYRFIDRENADSGTFNYVKGIFDKIN
                     TLLGSNDPINNKDLQLAYKELEQAVALIRTMPQRQQTSRRSNRIQTRSVESRAAEPRS
                     VSDYQNANSSYYVENANDGSGYPVGTYINASSKGAPYNLPTTPWNTLKASDSKEIALM
                     TAKQTGDGYQWVIKFNKGHAPHQNMIFWFALPADQVPVGRTDFVTVNSDGTNVQWSHG
                     AGAGANKPLQQMWEYGVNDPDRSHDFKIRNRSGQVIYSWPTVHVYSLEDLSRASDYFS
                     EAGATPATKAFGRQNFEYINGQKPAESPGVPKVYTFIGQGDASYTISFKTQGPTVNKL
                     YYAAGGRALEYNQLFMYSQLYVESTQDHQQRLNGLRQVVNRTYRIGTTKRVEVSQGNV
                     QTKKVLESTNLNIDDFVDDPLSYVKTPSNKVLGFYPTNANTNAFRPGGVQELNEYQLI
                     QLFTDQKLQEAARTRNPIRLMIGFDYPDGYGNSETLVPVNLTVLPEIQHNIKFFKNDD
                     TQNIAEKPFSKQAGHPVFYVYAGNQGNASVNLGGSVTSIQPLRINLTSNENFTDKDWQ
                     ITGIPRTLHIENSTNRTNNARERNIELVGNLLPGDYFGTIRFGRKEQLFEIRVKPHTP
                     TITTTAEQLRGTALQKVPVNISGIPLDPSALVYLVAPTNQTTNGGSEADQIPSGYTIL
                     ATGTPDGVHNTITIRPQDYVVFIPPVGKQIRAVVYYNKVVASNMSNAVTILPDDIPPT
                     INNPVGINAKYYRGDEVNFTMGVSDRHSGIKNTTITTLPSGWTSNLTKSDNKNGSLAI
                     TGRVSMNQAFNSDITFKVSATDNVNNTTNDSHSKHVSIHVGKISEDAHPIVLGNTEKV
                     VVVNPTAVSNDEKQSIITAFMNKNQNIRGYLASTDPVTVDNNGNVTLHYRDGSSTTLD
                     ATNVMTYEPVVKSEYQTANAAKTATVTIAKGQSFNIGDIKQYFTLSNGQAIPNGTFTN
                     ITSDRTIPTAQEVSQMNAGTQLYHIVASNAYHKDTEDFYISLKIVDVKQPEGDQRVYR
                     TSTYDLTTDEISKVKQAFINANRDVITLAEGDISVTNTPNGANVSTITVNINKGRLTK
                     SFASNLANMNFLRWVNFPQDYTVTWTNAKIANRPTDGGLSWSDDHKSLIYRYDATLGT
                     QITTNDILTMLKATTTVPGLRNNITGNEKAQAEAGGRPNYRTTGYSQSNATTDGQRQF
                     TLNGQVIQILDIINPSNGYGGQPVTNSNTRANHSNSTVVNVNEPAANGAGAFTIDHVV
                     KSNSTHNASDAVYKAQLYLTPYGPKQYVEHLNQNTGNTTDAINIYFVPSDLVNPTISV
                     GNYTNHQMFSGETFTNTITANDNFGVQSVTVPNTSQITGTVDNNHQHVSATAPNVTSA
                     TSKTINLLATDTSGNTATTSFNVTVKPLRDKYRVGTSSTAANPVRIANISNNATVSQA
                     DQTTIINSLTFTSNAPNRNYATASANEITSKTVSNVSRTGNNANVTVTVTHQDGTTST
                     VTVPVKHVIPEIVAHSHYTVQGQDFPAGNGSSAADYFKLSNGSAIPDATITWVSGQAP
                     NKDNTRIGEDITVTAHILIDGETTPITKTATYKVVRTVPKHVFETARGVLYPGVSDMY
                     DAKQYVKPVNNSWSTNAQHMNFQFVGTYGPNKDVVGISTRLIRVTYDNRQTEDLTILS
                     KVKPDPPRIDANSVTYKAGLTNQEIKVNNVLNNSSVKLFKADNTPLNVTNITHGSGFS
                     SVVTVSDALPNGGIKAKSSISMNNVTYTTQDEHGQVVTVTRNESVDSNDSASVTVTPQ
                     LQATTEGAVFIKGGDGFDFGHVERFIQNPPHGATVAWHDSPDTWKNTVGNTHKTAVVT
                     LPSGQGTRNVEVPVKVYPVANAKAPSRDVKGQNLTHGTNAIDYITFDPNTNTNGITAA
                     WANRQQPNNQQAGVQHLNVDVTYPGISAAKRVPVTVNVYQFEFPQTTYTTTVGGTLAS
                     GTQASGYAHMQNASGLPTDGFTYKWNRDTTGTNDANWAAMNKPNTAQVVNAKYDVIYN
                     GHTFATSLPAKFVVKDVQPAKPTVTETAAGAITIAPGANQTVNTHAGNVTTYADKLVI
                     KRNGNVVTTFTRRNNTSPWVKEASADNVTGIVGTNNGITVAAGTFNPADTIQVVATQG
                     SGETISDEQRSDDFTVVAPQPNQATTKIWQNGHIDITPNNPSGHLINPTQAMDIAYTE
                     KVGNGAEHSKTINVVRGQNNQWTIANKPDYVTLDAQTGKVTFNANTIKPNLSITITPK
                     AGTGHSVSSNPSTLTAPAAHTVNTTEIVKDYGSNVTAAEINNAVQVANKRTATIKNGT
                     AMPTNLAGGSTTTIPVTVTYNDGSTEEVQESIFTKADKRELITAKNHLDDPVSTEGKK
                     PGTITQYNNAMHNAQQQINTAKTEAQQVINNERATPQQVSDALTKVRAAQTKIDQAKA
                     LLQNKEDNSQLVTSKNNLQSSVNQVPSTAGMTQQSIDNYNAKKREAETEITAAQRVID
                     NGDATAQQISDEKHRVDNALTALNQAKHDLTADTHALEQAVQQLNRTGTTTGKKPASI
                     TAYNNSIRALQSDLTSAKNSANAIIQKPIRTVQEVQSALTNVNRVNERLTQAINQLVP
                     LADNSALRTAKTKLDEEINKSVTTDGMTQSSIQAYENAKRAGQTETTNAQNVINNGDA
                     TDQQIAAEKTKVEEKYNSLKQAIAGLTPDLAPLQTAKTQLQNDIDQPTSTTGMTSASV
                     AAFNDKLSAARTKIQEIDRVLASHPDVATIRQNVTAANAAKTALDQARNGLTVDKAPL
                     ENAKNQLQHSIDTQTSTTGMTQDSINAYNAKLTAARNKVQQINQVLAGSPTVDQINTN
                     TSAANQAKSDLDHARQALTPDKAPLQNAKTQLEQSINQPTDTTGMTTASLNAYNQKLQ
                     AARQKLTEINQVLNGNPTVQNINDKVAEANQAKDQLNTARQGLTLDRQPALTTLHGAS
                     NLNQAQQNNFTQQINAAQNHAALETIKSNITALNTAMTKLKDSVADNNTIKSGQNYTD
                     ATPANKQAYDNAVNAAKGVIGETTNPTMDVNTVNQKAASVKSTKDALDGQQNLQRAKT
                     EATNAITHASDLNQAQKNALTQQVNSAQNVQAVNDIKQTTQSLNTAMTGLKRGVANHN
                     QVVQSDNYVNADTNKKNDYNNAYNHANDIINGNAQHPVITPSDVNNALSNVTSKEHAL
                     NGEAKLNAAKQEANTALGHLNNLNNVQRQNLQSQINGAHQIDAVNTIKQNATNLNSAM
                     GNLRQAVADKDQVKRTEDYADADTAKQNAYNSAVSSAETIINQTANPTMSVDDVNRAT
                     SAVTTNKNALNGDEKLVQSKTDAARAIDALPHLNNAQKADVKSKINAASNIAGVNTVK
                     QQGTDLNTAMGNLQGAINDEQTTLNSQNYQDATPSKKTAYTNAVQAAKDILNKSNGQN
                     KTKDQVTEAMNQVNSAKNNLDGTRLLDQAKQTAKQQLNNMTHLTTAQKTNLTNQINSG
                     TTVAGVHTVQSNANTLDQAMNTLRQSIANNDATKASEDYVDANNDKQTAYNNAVAAAE
                     TIINANSNPEMNPSTITQKAEQVNSSKTALNGDENLATAKQNAKTYLNTLTSITDAQK
                     NNLISQISSATRVSGVDTVKQNAQHLDQAMANLQNGINNESQVKSSEKYRDADTNKQQ
                     EYDNAITAAKAILNKSTGPNTAQNAVEAALQRVNTAKDALNGDAKLIAAQNAAKQHLG
                     TLTHITTAQRNDLTNQISQATNLAGVESVKQSANSLDGAMGNLQTAINDKSGTLASQN
                     FLDADEQKRNAYNQAISAAETILNKQTGPNTAKTAVEQALNNVNSAKHALNGTQNLNN
                     AKQAAITAINGASDLNQKQKDALKAQANGAQRVSNANDVQRNATELNTAMGQLQHAIA
                     DKTNTLASSKYVNADSTKQNAYTTKVTNAEHIISGTPTVVTTPSEVTAAANQVNRAKQ
                     ELNGDERLRVAKQNANTAIDALTQLNTPQKAKLKEQVGQANRLEDVQSVQTNGQSLNN
                     AMKGLRDSIANETTVKASQNYTDASPNNQSTYNSAVSNAKGIINQTNNPTMDTSAITQ
                     ATTQVNNAKNGLNGAENLRNAQNTAKQNLNTLSHLTNNQKSAISSQIDRAGHVSEVTA
                     AKNAATELNAQMGNLEQAIHDQNTVKQGVNFTDADKAKRDAYTNAVSRAETILNKTQG
                     ANTSKQDVEAAIQNVTSAKNALNGDQNVTNAKNAAKNALNNLTSINNAQKRDLTTKID
                     QATTVAGVEAVSNTGTQLNTAMANLQNGINDKANTLASENYHDADSDKKTAYTQAVTN
                     AENILNKNSGSNLDKAAVENALSQVTNAKGALNGNHNLEQAKSNANTTINGLQHLTTA
                     QKDKLKQQVQQAQNVAGVDTVKSSANTLNGAMGTLRNSIQDNTATKNGQNYLDATERN
                     KTNYNNAVDSANGVINATSNPNMDANAINQIATQVTSTKNALDGTHNLTQAKQTATNA
                     IDGATNLNKAQKDALKAQVTSAQRVANVTSIQQTANELNTAMGQLQHGIDDENATKQT
                     QKYRDAEQSKKTAYDQAVAAAKAILNKQTGSNSDKAAVDRALQQVTSTKDALNGDDKL
                     AEAKAAARQNLGTLNHITNAQRTALEGQINQATTVDGVNTVKTNANTLDGDMNSLQGA
                     INDKDATLRNQNYLDADESKRNAYTQAVTAAEGILNKQTGGNTSKADVDNALNAVTRA
                     KAALNGAENLRNAKTSATNTINGLPNLTQLQKDNLKHQVEQAQNVVGVNGVKDKGNTL
                     NTAMGALRTSIQNDNTTKTSQNYLDASDSNKNNYNTAVNNANGVINATNNPNMDANAI
                     NDMANQVNTTKAALNGAQNLAQAKTNATNTINNAQDLNQKQKDALKTQVNNAQRVSDA
                     NNVQHTATELNGAMTALKAAIADKERTKASGNYVNADQEKRQAYDSKVTNAENIINGT
                     PNATLTVNDVNSAASQVNAAKTALNGDNNLRVAKEHANNTIDGLAQLNNVQKAKLKEQ
                     VQSATTLDGVQTVKNSSQTLNTAMKGLRDSIANEATIKAGQNYTDASPNNRNEYDSAV
                     TAAKAIINQTSNPTMEPNTITQATSQVTTKEHALNGAQNLAQAKTTAKNNLNNLTSIN
                     NAQKDALTRNIDGATTVAGVNQETAKATELNNAMHSLQNGINDETQTKQTQKYLDAEP
                     SKKSAYDQAVNAAKAILTKASGQNVDKAAVEQALQNVNSTKTALNGDAKLNEAKAAAK
                     QTLGILTHINNAQRNALDNEITQATNVEGVNTVKAKAQQLDGAMGQLETSIRDKDTTL
                     QSQNYQDADDAKRTAYSQAVNAAATILNKTAGGNTPKADVERAMQAVTQANTALNGIQ
                     NLERAKQAANTAITNASDLNTKQKEALKAQVTSAGRVSAANGVEHTATELNTAMTALK
                     RAIADKADTKASGNYVNADANKRQAYDEKVTAAEHIVSGTPTPTLTPSDVTNAATQVT
                     NAKTQLNGNHNLEVAKQNANTAIDGLTSLNGPQKAKLKEQVGQATTLPNVQTVRDNAQ
                     TLNTAMKGLRDSIANEATIKAGQNYTDASQNKQNDYNNAVTAAKAIIGQTTSPSMIAQ
                     EINQAKDQVTAKQQALNGQENLRTAQTNAKQHLNGLSDLTNAQKDAAKRQIEGATHVN
                     EVTQAQNNADALNTAMTNLKNGIQDQNTIKQGVNFTDADEAKRNAYTNAVTQAEQILN
                     KAQGPNTAKDGVETALQNVQRAKNELNGNQNVANAKTTAKNALNNLTSINNAQKAALK
                     SQIEGATTVAGVNQVSTMASELNTAMSNLQRGINDEAATKAAQKYTEADRDKQTAYND
                     AVTAAKTLLDKTAGSNDNKVAVEQALQRVNTAKTALNGDARLNEAKNTAKQQLATMSH
                     LTNAQKANLTEQIERGTTVAGVQGIQANAGTLNQAMNQLRQSIASKDATKSSEDYQDA
                     NADLQNAYNDAVTNAEGIISATNNPEMNPDTINQKASQVNSAKSALNGDEKLAAAKQT
                     AKSDIGRLTDLNNAQRTAANAEVDQAPNLAAVTAAKNKATSLNTAMGNLKHALAEKDN
                     TKRSVNYTDADQPKQQAYDTAVTQAEAITNANGSNANETQVQAALNQLNQAKNDLNGD
                     NKVAQAKETAKRALASYSNLNNAQSTAATSQIDNATTVADVTAAQNTANELNTAMGQL
                     QNGINDQNTVKQQVNFTDADQGKKDAYTNAVTNAQGILDKANGQNMTKAQVEAALNQV
                     TTAKNALNGDANVRQAKSDAKANLGTLTHLNNAQKQDLTSQIEGATTVNGVNSVKTKA
                     QDLDGAMQRLESAIANKDQTKASENYIDADPTKKTAFDNAITQAESYLNKDHGTNKDK
                     QAVEQAIQSVTSTENALNGDANLQCAKTEATQAIDNLTQLNTPQKTALKQQVNAAQRV
                     SGVTDLKNSATSLNNAMDQLKQAIGDHDTIVAGGNYTNASPDKQGAYTDAYNAAKNIV
                     NGSPNVITNAADVTAATQRVNNAETSLNGDTNLATAKQQAKDALRQMTHLSDAQKQSI
                     TGQIDSATQVTGVQSVKDNATNLDNAMNQLRNSIANKDEVKASQPYVDADTDKQNAYN
                     TAVTSAENIINATSQPTLDPSAVTQAANQVNTNKTALNGAQNLANKKQETTANINRLS
                     HLNNAQKQDLNTQVTNAPNISTVNQVKTKAEQLDQAMERLINGIQDKDQVKQSVNFTD
                     ADPEKQTAYNNAVTAAENIINQANGTNANQSQVEAALSTVTTTKQALNGDRKVTDAKN
                     NANQTLSTLDNLNNAQKGAVTGNINQAHTVAEVTQAIQTAQELNTAMGNLKNSLNDKD
                     TTLGSQNFADADPEKKNAYNEAVRNAENILNKSTGTNVPKDQVEAAMNQVNTTKAALN
                     GTQNLEKAKQHANTAIDGLSHLTNAQKEALKQLVQQSTTVAEAQGNEQKANNVDAAMD
                     KLRQSIADNATTKQNQNYTDASPNKKDAYNNVVTTAQGIIDQTTNPSLDPTVINQAAG
                     QVSTSKNALNGNENLEAAKQQATQSLGSLDNLNNAQKQAVTNQINGAHTVDEANQIKQ
                     NAQNLNTAMGNLKQAIADKDATKATVNFTDADQAKQQAYNTAVTNAENIISKANGGNA
                     TQTEVEQAIQQVNAAKQALNGNANVQHAKDEATALINNSNDLNQAQKDALKQQVQNAT
                     TVAGVNNVKQTAQELNNAMTQLKQGIADKEQTKADGNFVNADSDKQNAYNQAVAKAEA
                     LISGTPDVVVTPSEITAALNKVTQAKNDLNGNTNLATAKQNVQHAIDQLPNLNQAQRD
                     EYSKQITQATLVPNVNAIQQAATTLNDAMTQLKQGIANKAQIKGSENYHDADTDKQTA
                     YDNAVTKAEELLKQTTNPTMDPNTIQQALTKVNDTNQALNGNQKLADAKQDAKTTLGT
                     LDHLNDAQKQALTTQVEQAPDIATVNNVKQNAQNLNNAMTNLNNALQDKTETLNSINF
                     TDADQAKKDDYTNAVSHAEGILSKANGSNASQTEVEQAMQRVNEAKQALNGNDNVQRA
                     KDAAKQVITNANDLNQAQKDALKQQVDAAQTVANVNTIKQTAQDLNQAMTQLKQGIAD
                     KDQTKANGNFVNADTDKQNAYNNAVAHAEQIISGTPNANVDPQQVAQALQQVNQAKGD
                     LNGNHNLQVAKDNANTAIDQLPNLNQPQKTALKDQVSHAELVTGVNAIKQNADALNNA
                     MGTLKQQIQANSQVPQSVDFTQADQDKQQAYNNAANQAQQIANGTPTPVLAPDTVTKA
                     VTTMNQAKDALNGDEKLAQAKQDALANLDTLRDLNQPQRDALRNQINQAQALATVEQT
                     KQNAQNVNTAMGNLKQGIANKDTVKASENYHDADVDKQTAYTNAVSQAEGIINQTTNP
                     TLNPDDITRALTQVTDAKNSLNGEAKLATEKQNAKDAVSGMTHLNDAQKQALKGQIDQ
                     SPEIATVNQVKQTATSLDQAMDQLSQAINDKDQILADGNYLNADPDKQNAYKQAVAKA
                     EALLNKQSGTNEVQAQVESITNEVNAAKQALNGNDNLANAKQQAKQQLANLTHLNDAQ
                     KQSFESQITQAPLVTDVTTINQKAQTLDHAMELLRNSVADNQTTLASEDYHDATAQRQ
                     NDYNKAVTAANNIINQTTSPTMNPDDVNGATTQVNNTKVALDGDENLAAAKQQANNRL
                     DQLDHLNNAQKQQLQSQITQSSDIAAVNGHKQTAESLNTAMGNLINAIADHQAVEQRG
                     NFINADTDKQTAYNTAVNEAAAMINKQTGQNANQTEVEQAITKVQTTLQALNGDHNLQ
                     VAKTNATQAIDALTSLNDPQKTALKDQVTAATLVTAVHQIEQNANTLNQAMHGLRQSI
                     QDNAATKANSKYINEDQPEQQNYDQAVQAANNIINEQTATLDNNAINQVAATVNTTKA
                     ALHGDVKLQNDKDHAKQTVSQLAHLNNAQKHMEDTLIDSETTRTAVKQDLTEVQALDQ
                     LMDALQQSIADKDATRASSAYVNAEPNKKQAYDEAVQNAESIIAGLNNPTINKGNVSS
                     ATQAVISSKNALDGVERLAQDKQTAGNSLNHLDQLTPAQQQALENQINNATTRDKVAE
                     IIAQAQALNEAMKALKESIKDQPQTEASSKFINEDQAQKDAYTQAVQHAKDLINKTTD
                     PTLAKSIIDQATQAVTDAKNNLHGDQKLAQDKQRATETLNNLSNLNTPQRQALENQIN
                     NAATRGEVAQKLTEAQALNQAMEALRNSIQDQQQTESGSKFINEDKPQKDAYQAAVQN
                     AKDLINQTGNPTLDKAQVEQLTHAFKQAKDNLHGDQKLADDKQHAVTDLNQLNGLNNP
                     QRQALESQINNAATRGEVAQKLAEAKALDQAMQALRNSIQDQQQTEAGSKFINEDKPQ
                     KDAYQAAVQNAKDLINQTGNPTLDKSQVEQLTQAVTTAKDNLHGDQKLARDQQQAVTT
                     VNALPNLNHAQQQTLTDAINAAPTRTEVAQHVQTATELDHAMETLKNKVDQVNTDKAQ
                     PNYTEASTDKKEAVDQALQAAQSITDPTNGSNANKDAVEQALTKLQEKVNELNGNERV
                     AEAKTQAKQTIDQLTHLNADQIATAKQNIDQATKLQPIAELVDQATQLNQSMDQLQQA
                     VNEHANVEQTIDYTQADSDKQKAYKQAIADAENVLKQNANKQQVDQALQNILNAKQAL
                     NGDERVALAKTNGKHDIDQLNALNNAQQDGFKGRIDQSNDLNQIQQIVDEAKALNRAM
                     DQLSQEITGNEGRTKGSTNYVNADTQVKQVYDEAVDKAKQALDKSSGQNLTAEQVIKL
                     NDAVTAAKKALNGEERLNNRKAEALQRLDQLTHLNNAQRQLAIQQINNAETLNKASRA
                     INRATKLDNAMGAVQQYIDEQHLGVISSTNYINADDNLKANYDNAIANAAHELDKVQG
                     NAIAKAEAEQLKQNIIDAQNALNGDQNLANAKDKANAFVNSLNGLNQQQQDLAHKAIN
                     NADTVSDVTDIVNNQIDLNDAMETLKHLVDNEIPNAEQTVNYQNADDNAKTNFDDAKR
                     LANTLLNSDNTNVNDINGAIQAVNDAIHNLNGDQRLQDAKDKAIQSINQALANKLKEI
                     EASNATDQDKLIAKNKAEELANSIINNINKATSNQAVSQVQTAGNHAIEQVHANEIPK
                     AKIDANKDVDKQVQALIDEIDRNPNLTDKEKQALKDRINQILQQGHNDINNALTKEEI
                     EQAKAQLAQALQDIKDLVKAKEDAKQDVDKQVQALIDEIDQNPNLTDKEKQALKDRIN
                     QILQQGHNGINNAMTKEEIEQAKAQLAQALKEIKDLVKAKENAKQDVDKQVQALIDEI
                     DQNPNLTDKEKQALKDRINQILQQGHNDINNAMTKEEIEQAKAQLAQALQDIKDLVKA
                     KEDAKNAIKALANAKRDQINSNPDLTPEQKAKALKEIDEAEKRALQNVENAQTIDQLN
                     RGLNLGLDDIRNTHVWEVDEQPAVNEIFEATPEQILVNGELIVHRDDIITEQDILAHI
                     NLIDQLSAEVIDTPSTATISDSLTAKVEVTLLDGSKVIVNVPVKVVEKELSVVKQQAI
                     ESIENAAQQKIDEINNSVTLTLEQKEAAIAEVNKLKQQAIDHVNNAPDVHSVEEIQQQ
                     EQAYIEQFNPEQFTIEQAKSNAIKSIEDAIQHMIDEIKARTDLTDKEKQEAIAKLNQL
                     KEQAIQAIQRAQSISEITEQLEQFKAQMKAANPTAKELAKRKQEAISRIKDFSNEKIN
                     SIRNSEIGTADEKQAAMNQINEIVLETIRDINNAHTLQQVEAALNNGIARISAVQIVI
                     SDRAKQSSSTGNESNSHLTIGYGTANHPFNSSTIGHKKKLDEDDDIDPLHMRHFSNNF
                     GNVIKNAIGVVGISGLLASFWFFIAKRRRKEDEEEELEIRDNNKDSIKETLDDTKHLP
                     LLFAKRRRKEDEEDVTVEEKDSLNNGESLDKVKHTPFFLPKRRRKEDEEDVEVTNENT
                     DEKVLKDNEHSPLLFAKRRKDKEEDVETTTSIESKDEDVPLLLAKKKNQKDNQSKDKK
                     SASKNTSKKVAAKKKKKKSKKNKK"
     gene            complement(32170..32571)
                     /locus_tag="RFE25_001331"
     CDS             complement(32170..32571)
                     /locus_tag="RFE25_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HDU2816402.1"
                     /translation="MAKINFDAATKGNPGISTCAIVIKEDKQHYTYTHELGEMDNHTA
                     EWAACIYALEHARELNVQNALLYTDSKLIADSIEAGYVKNANFKPYFDQIEIFEKDFD
                     LLFVKWIPREQNKEANQHAQQALYKLIKKNK"
     gene            complement(33054..33758)
                     /locus_tag="RFE25_001332"
     CDS             complement(33054..33758)
                     /locus_tag="RFE25_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="queuosine precursor transporter"
                     /protein_id="HDU2816403.1"
                     /translation="MYNEILGLVTFIATFVLMVLMYRFFGKQGLIAWVAIGTIIANIQ
                     VIKTVEIFGISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQL
                     SLHFIPAPEDMAQKALHAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVFSSDKTF
                     FIRAYGSTFLSSIIDTALFVAIAFIGSLPGTVVFEIFITTYVLKLASTVFNVPFGYIA
                     KSFYRKGKIDKLDQGY"
     gene            34003..34197
                     /locus_tag="RFE25_001333"
     CDS             34003..34197
                     /locus_tag="RFE25_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-finger domain-containing protein"
                     /protein_id="HDU2816404.1"
                     /translation="MSRILTFSEQNALVKIDDLMNTYCNQCPIKTRLRKLEGKTKAHH
                     FCINECSIGKEIKQLGNELQ"
     gene            34209..34460
                     /locus_tag="RFE25_001334"
     CDS             34209..34460
                     /locus_tag="RFE25_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU N-terminal domain-containing protein"
                     /protein_id="HDU2816405.1"
                     /translation="MKIISISETPNHNTMKITLSESREGMTSDTYTKVDDSQPAFIND
                     ILKVEGVKSIFHVMDFISVDKENDANWETVLPKVEAVFE"
     gene            34498..35622
                     /locus_tag="RFE25_001335"
     CDS             34498..35622
                     /locus_tag="RFE25_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor C"
                     /protein_id="HDU2816406.1"
                     /translation="MEILRIEPTPSPNTMKVVLSYTREDKLSNTYKKVEETQPRFINQ
                     LLSIDGITSIFHVMNFLAVDKAPKADWEVILPDIKAAFSDANKVLESVNEPQIDNHFG
                     EIKAELLTFKGIPYQIKLTSADQELREQLPQTYVDHMTQAQTAHDNIVFMRKWLDLGN
                     RYGNIEEVMDGVLEEVLATYPESQLPVLVKHALEENHATNNYHFYRHVSLDEYHATDN
                     WKTRLRMLNHFPKPTFEDIPLLDLALSDEKVPVRRQAIVLLGMIESKEILPYLYKGLR
                     DKSPAVRRTAGDCISDLGYPEALPEMVLLLDDPQKIVRWRAAMFIFDEGNAEQLPALK
                     AHINDNAFEVKLQIEMAISRIENGDEALGSVWKQMANRTI"
     gene            35638..36075
                     /locus_tag="RFE25_001336"
     CDS             35638..36075
                     /locus_tag="RFE25_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrxA/BrxB family bacilliredoxin"
                     /protein_id="HDU2816407.1"
                     /translation="MNAYDAYMKEIAQQMRGELTQNGFTSLETSEAVSEYMNQVNADD
                     TTFVVINSTCGCAAGLARPAAVAVATQNEHRPTNTVTVFAGQDKEATATMREFIQQAP
                     SSPSYALFKGQDLVYFMPREFIEGRDINDIAMDLKDAFDENCK"
BASE COUNT        14644 a         6413 c         6493 g         8834 t
ORIGIN      
        1 tttaccttac aatatatttt gtgttattat attctggagc ataaataaat tgttcaacac
       61 atagttgtaa tgtgtttcaa tactttttgg atagattgcg aaattgtatt gaatcgtcat
      121 cgttttaaat ttttaaatga gaatggaatg agcattacaa tatacaagca atcaaaagta
      181 aatacattca caacacaaca gagacataac aacaagataa ggagtgaaca atagctgtga
      241 attatcgtga taaaattcaa aagtttagta ttcgtaaata tacagttggt acattttcaa
      301 ctgtcattgc gacattggta tttttaggat tcaatacatc acaagcacat gctgctgaaa
      361 caaatcaacc agcaagcgtg gttaaacaga aacaacaaag taataatgaa cagactgaga
      421 atcgagaatc tcaagtacaa aattctcaaa attcacaaaa tagtcaatca ttatccgcta
      481 ctcatgaaaa tgagcaacca aataatagtc aagctaattt agtaaatcaa aaagtagcgc
      541 aatcatctac tactaatgat gaacaaccag catctcaaaa tgtaaataca aagaaagatt
      601 cggcaacggc tgcgacaaca caaccagata aagaagaaag taagcataaa caaaacgaaa
      661 gtcaatctgc taataaaaat ggaaacgaca atagagcggc tcatgtagaa aatcatgaag
      721 caaatgtagt aacagcttca gattcatctg ataatggtaa cgtacaacat gaccgaaatg
      781 aattacaagc attttttgat gcaaattatc atgattatcg ctttattgac cgtgaaaatg
      841 cagattctgg cacatttaac tatgtaaaag gcatttttga caagattaat actttattag
      901 gcagtaatga tccaattaac aataaagact tgcaacttgc atacaaagaa ttggaacaag
      961 ctgttgcttt aattcgtaca atgcctcaac gtcaacaaac tagccgtcga tcaaacagaa
     1021 ttcaaacgcg ttctgttgag tctagagctg cagagcctag atcagtatca gactatcaaa
     1081 atgcaaattc atcatattat gttgaaaatg ctaatgatgg ttcaggatat cctgtaggta
     1141 catatatcaa tgcttctagt aaaggggcgc catataattt accaactaca ccatggaata
     1201 cattgaaggc ctctgactca aaggaaattg ctcttatgac agcgaaacaa actggagatg
     1261 gctaccaatg ggttattaag tttaataaag gacatgctcc acatcaaaat atgattttct
     1321 ggtttgcatt accagcagac caagtgccag taggaagaac tgactttgta acagttaatt
     1381 cagatggaac aaatgtacaa tggagtcatg gagcaggagc aggtgcaaat aaaccacttc
     1441 aacaaatgtg ggaatatgga gtaaatgatc ctgatcgttc acatgacttt aaaataagaa
     1501 atagaagtgg ccaagtaata tatagctggc caactgtcca tgtttattct ttagaagatt
     1561 tatctagagc gagtgattat tttagtgaag ctggagcgac acctgctact aaagcatttg
     1621 gtagacaaaa ttttgaatat attaatggtc aaaaacctgc tgaatcaccg ggtgttccta
     1681 aagtttatac tttcatcggt caaggtgatg caagttatac aatttcattt aaaacacaag
     1741 gtccaactgt taataaattg tattatgcag caggtgggcg tgctttagag tacaatcaat
     1801 tatttatgta cagtcaacta tacgtcgaat caacgcaaga ccatcaacaa cgtcttaatg
     1861 gtttaagaca agtggttaat cgtacatatc gcataggtac aactaaacgt gtagaagtga
     1921 gtcaaggaaa tgtacaaacg aaaaaggtat tagaaagtac aaacctaaat atagatgatt
     1981 ttgttgatga tcctttaagt tatgttaaga cgccgagtaa taaagtgtta ggtttttacc
     2041 caactaatgc aaatactaac gcttttagac cggggggcgt tcaagaatta aatgaatatc
     2101 aattaattca attatttact gatcaaaaat tacaagaagc agcaagaact agaaacccaa
     2161 taagattaat gattggtttc gactatcctg atggttatgg taatagtgaa actttagttc
     2221 ctgttaactt aacggtatta cctgaaatcc aacataatat taaattcttt aaaaatgacg
     2281 atactcaaaa tattgctgaa aaaccatttt caaaacaagc tgggcatcca gttttctatg
     2341 tatatgcagg taaccaaggg aatgcttccg tgaatttagg tggtagcgta acatctattc
     2401 aaccattacg tattaattta acaagtaatg agaattttac agataaagat tggcaaatta
     2461 caggtattcc gcgtacatta cacattgaaa actcgacaaa tagaactaat aatgctagag
     2521 aacgtaacat tgaacttgtt ggtaatttat taccagggga ttactttggt acgatacgtt
     2581 ttggacgtaa agaacaatta tttgaaattc gtgttaaacc acatacacca acaattacaa
     2641 cgacagctga gcaattaaga ggtacagcat tacaaaaagt gcctgttaat atttcgggaa
     2701 taccgttgga tccatcggca ttggtttatt tagttgcacc aacaaatcaa actacgaatg
     2761 gtggtagtga ggcagatcaa ataccatctg gttatacgat acttgcgact ggtacacctg
     2821 atggggtgca taatacaatt actatacgac cgcaagatta tgttgtattc ataccacctg
     2881 taggtaaaca aattagagca gtagtttatt ataataaagt agttgcatct aatatgagta
     2941 atgctgttac tattttgcca gatgacattc caccaacaat caataatcct gttggaataa
     3001 atgccaaata ctatcgaggc gacgaagtca actttacaat gggagtctct gatagacatt
     3061 ctggtataaa aaatacaact attactactt tgccaagtgg ttggacatca aatttaacta
     3121 aatccgacaa caaaaacggc tcattagcta ttacaggtag agtctctatg aatcaggcat
     3181 ttaacagtga tattacattt aaagtatcag cgacagacaa tgtcaataat acgacaaatg
     3241 atagtcattc taaacatgtg tcaattcatg taggtaaaat tagtgaagat gctcatccga
     3301 ttgtattagg aaatactgag aaagttgtag tagtcaatcc gactgctgta tctaatgatg
     3361 aaaagcaaag cataattact gcctttatga ataaaaacca aaatataaga ggatatttag
     3421 catcaactga tccagtaact gtcgataata atggtaacgt cacattacat taccgtgatg
     3481 gctcatcaac aacgcttgat gctacaaatg tgatgacata cgaaccagtt gtgaaatctg
     3541 aatatcaaac tgccaatgct gctaaaacag caacggtaac gattgctaaa ggacaatcat
     3601 ttaatattgg tgatattaaa caatatttta ctttaagtaa tggacaagct attccaaatg
     3661 gcacatttac aaatattaca tctgatagaa ctattccaac tgcacaagaa gttagtcaaa
     3721 tgaatgcagg tacgcagtta tatcatatag ttgcttcaaa tgcatatcat aaagacactg
     3781 aagatttcta tattagttta aaaatcgttg atgtgaaaca acctgaaggc gatcaacgtg
     3841 tctatcgtac gtcaacatat gatttaacca ctgatgaaat ctcaaaagta aaacaagctt
     3901 ttattaatgc aaatagagat gtaattacgc ttgccgaagg tgatatttca gttacaaata
     3961 cacctaatgg tgctaatgta agtactatta cagtaaatat taataaaggt cgattaacga
     4021 aatcattcgc gtctaaccta gctaatatga atttcttgcg ttgggttaat ttcccacaag
     4081 attatacagt gacatggacg aatgcaaaaa ttgcaaacag accaacagat ggtggtttat
     4141 catggtccga tgaccataaa tctttaattt atcgttatga tgctacatta ggcacacaaa
     4201 ttacaactaa tgatatttta acgatgctaa aagcgactac tacagtgcct ggattgcgta
     4261 ataatattac tggtaatgaa aaagcacaag cagaagcagg tggaagacca aactatagaa
     4321 caactggtta ttcacaatca aatgcgacaa ctgatggtca acgtcaattt acgttgaatg
     4381 gtcaagtgat tcaaatatta gacatcatca acccttcaaa cggttatggt gggcaacctg
     4441 ttacaaattc aaatactcgt gcaaaccata gtaactcaac tgttgttaac gtaaacgaac
     4501 cggcagctaa tggtgctggc gcatttacaa ttgaccacgt tgtaaaaagt aattctacac
     4561 ataatgcaag tgatgcagtt tataaagcgc agttatactt aacgccatat ggtccaaaac
     4621 aatatgttga acatttaaat caaaatacag gaaatactac tgacgctatt aacatttatt
     4681 ttgtaccaag tgacttagtg aatccaacaa tttcagtagg taattacact aatcatcaaa
     4741 tgttctcagg tgaaacattt acaaatacga ttacagcgaa tgataacttt ggtgtgcaat
     4801 cggtaactgt accaaataca tcacaaatta caggtactgt tgataataac catcaacatg
     4861 tttctgcaac ggcaccaaat gtgacatcag caactagtaa gacaatcaat ttattagcaa
     4921 ctgatacaag tggtaataca gctacaactt cattcaatgt aacagtgaaa cctttgcgtg
     4981 ataaatatcg agttggtact tcatcaacgg ctgctaatcc tgttagaatt gccaatattt
     5041 cgaataatgc gacagtatca caagctgatc aaacgacaat tattaattcg ttaacgttta
     5101 caagtaatgc accaaataga aactatgcaa cagcaagcgc aaatgaaatc actagtaaaa
     5161 cagttagtaa tgtcagtcgt actggaaata atgccaatgt cacagtaact gttactcatc
     5221 aagatggaac aacatcaaca gtgactgtac ctgtaaagca tgtcattcca gaaatcgttg
     5281 cacattcgca ttacactgta caaggccaag acttcccagc aggtaatggt tctagtgcag
     5341 cagattactt taagttatct aatggtagtg ccattccaga tgcaacgatt acatgggtaa
     5401 gtggacaagc gccaaataaa gataatacac gtattggtga agatataaca gtaactgcac
     5461 atatcttaat tgatggcgaa acaacgccga ttacgaaaac agcaacatat aaagtagtaa
     5521 gaactgtacc gaaacatgtc tttgaaacag ccagaggtgt tttataccca ggtgtttcag
     5581 atatgtatga tgcgaaacaa tatgttaagc cagtaaataa ttcttggtcg acaaatgcgc
     5641 aacatatgaa ttttcaattt gttggaacat atggtcctaa caaagatgtt gtaggtatat
     5701 caacgcgtct tattagagtg acttatgata atagacaaac tgaagattta actattttat
     5761 ctaaagttaa acctgaccca ccaagaattg acgcaaactc tgtgacatat aaagcaggtc
     5821 ttacaaacca agaaattaaa gttaataacg tattaaataa ctcgtcagta aaattattta
     5881 aagcagataa tacaccatta aatgtcacaa atattactca tggtagtggt tttagttcgg
     5941 ttgtgacagt aagtgacgcg ttaccaaatg gcggaattaa agcaaaatct tcaatttcaa
     6001 tgaacaatgt gacgtatacg acgcaagacg aacatggtca agttgttaca gtaacaagaa
     6061 atgaatctgt tgattcaaat gatagtgctt ctgttacagt aacaccacaa ttacaagcaa
     6121 ctactgaagg cgctgtattt attaaaggtg gcgacggttt tgatttcggt catgtagaac
     6181 gatttattca aaatccgcca catggggcaa cggtcgcatg gcatgatagt ccagatacat
     6241 ggaagaatac agtcggcaac acacataaaa ctgcggttgt aacattacct agtggtcaag
     6301 gtacgcgtaa tgttgaagtt ccagtcaaag tttatccagt tgctaatgct aaggcgccat
     6361 cacgtgatgt gaaaggtcaa aatttgacac atggtacaaa cgctattgat tacattacat
     6421 ttgatccaaa tactaatacg aatggtatta cagcagcatg ggcaaataga caacaaccaa
     6481 ataaccagca agcaggcgtt caacatttaa atgtcgatgt cacatatcca ggtatttcag
     6541 ctgctaaacg agttcctgta actgtgaacg tatatcaatt tgaattccct caaactactt
     6601 atacaacaac agttggtggc actttagcaa gtggtacgca agcatcagga tatgcacata
     6661 tgcaaaacgc ttcaggttta ccaacagatg gatttacgta taaatggaat cgtgatacta
     6721 cgggtacaaa cgatgcaaac tgggcagcaa tgaataaacc aaatactgca caagtcgtta
     6781 atgcaaaata tgatgtcatc tataatggac atacatttgc aacatcttta ccagcgaaat
     6841 ttgtagtaaa agatgttcaa ccagcgaaac caactgtcac tgaaacagcg gcaggagcga
     6901 ttacaattgc acctggtgcg aaccaaacag tcaatactca tgctggtaat gttacgacat
     6961 atgctgacaa attagttatt aaacgtaatg gaaatgttgt aacgacattt acacgtcgta
     7021 ataatacgag cccatgggtg aaagaagcat cagcagataa tgtaacaggt attgttggaa
     7081 ctaataatgg tattactgtg gcagcaggta ctttcaatcc tgctgataca attcaagttg
     7141 ttgcaacaca aggtagtggc gaaacaatca gtgacgagca acgtagtgat gatttcacag
     7201 ttgtcgcacc acaaccgaac caagcgacta cgaaaatttg gcaaaatggt catattgata
     7261 tcacgcctaa taatccatca ggacatttaa ttaatccaac acaagcaatg gatattgctt
     7321 acactgaaaa agtgggtaat ggtgcagaac atagtaagac aattaatgtt gttcgtggtc
     7381 aaaataatca atggacaatt gcgaataagc ctgactatgt aacgttagat gcacaaactg
     7441 gtaaagtgac gttcaatgcc aatactataa aaccaaattt atcaatcaca attactccga
     7501 aagcaggtac aggtcactca gtaagtagta atccaagtac attaactgca ccggcagctc
     7561 atactgtcaa cacaactgaa attgtgaaag attatggttc aaatgtaaca gcagctgaaa
     7621 ttaacaatgc agttcaagtt gctaataaac gtactgcaac gattaaaaat ggcacagcaa
     7681 tgcctactaa tttagctggt ggtagcacaa cgacgattcc tgtgacagta acttacaatg
     7741 atggtagtac tgaagaagta caagagtcca ttttcacaaa agcggataaa cgtgagttaa
     7801 tcacagctaa aaatcattta gatgatccag taagcactga aggtaaaaag ccaggtacaa
     7861 ttacgcagta caataatgca atgcataatg cgcaacaaca aatcaatacc gcgaaaacag
     7921 aagcacaaca agtgattaat aatgagcgtg caacaccaca acaagtttct gacgcactaa
     7981 ctaaagttcg tgcagcacaa actaagattg atcaagctaa agcattactt caaaataaag
     8041 aagataatag ccaattagta acgtctaaaa ataacttaca aagttctgtg aaccaagtac
     8101 catcaactgc tggtatgacg caacaaagta ttgataacta taatgcgaag aagcgtgaag
     8161 cagaaactga aataactgca gctcaacgtg ttattgacaa tggcgatgca actgcacaac
     8221 aaatttcaga tgaaaaacat cgtgtcgata acgcattaac agcattaaac caagcgaaac
     8281 atgatttaac tgcagataca catgccttag agcaagcagt gcaacaattg aatcgcacag
     8341 gtacaacgac tggtaagaag ccggcaagta ttactgctta caataattcg attcgtgcac
     8401 ttcaaagtga cttaacaagt gctaaaaata gcgctaatgc tatcattcag aagccaataa
     8461 gaacagtgca agaggtacaa tctgcgttaa caaatgtaaa tcgtgtcaat gagcgattaa
     8521 cgcaagcaat taatcaatta gtacctttag ctgataatag tgctttaaga actgctaaga
     8581 cgaaacttga tgaagaaatc aataaatcag taactactga tggtatgaca caatcatcaa
     8641 tccaagcata tgaaaatgct aaacgtgcag gtcaaacaga aacaacaaat gcacaaaatg
     8701 ttattaacaa tggtgacgcg acagaccaac aaattgccgc agaaaaaaca aaagtagaag
     8761 aaaaatataa tagcttaaaa caagcaattg ctggattaac accagacttg gcaccattac
     8821 aaactgcaaa aactcagttg caaaatgata ttgatcagcc aacgagtacg actggtatga
     8881 caagcgcatc tgttgctgca tttaatgaca aactttcagc agctagaact aaaattcaag
     8941 aaattgatcg cgtactagca tctcatccag atgtagcaac gattcgtcaa aacgtgacag
     9001 cagcgaatgc tgctaaaaca gcacttgatc aagcgcgcaa tggcttaaca gtcgataaag
     9061 cacctttaga aaatgcgaaa aatcaactac aacatagtat tgatacgcaa acaagtacaa
     9121 ctggtatgac acaagactct ataaatgcat acaatgcgaa gttaacagct gcacgtaata
     9181 aggttcaaca aatcaatcaa gtattagcag gttcacctac tgtagatcaa attaatacaa
     9241 atacgtctgc agcaaatcaa gcgaaatctg atttagatca tgcacgtcaa gcgttaacac
     9301 cagataaagc gccgcttcaa aatgcgaaaa cgcaattaga acaaagcatt aatcaaccaa
     9361 cagatacaac aggtatgaca accgcttcgt taaatgcata caaccaaaaa ttacaagcag
     9421 cacgtcaaaa gttaactgaa attaatcaag tgttgaatgg caacccaact gtccaaaata
     9481 tcaatgataa agtggcagag gcaaaccaag ctaaggatca attaaataca gcacgtcaag
     9541 gtttaacatt agatagacag ccagcgttaa caacattaca tggtgcatct aacttaaacc
     9601 aagcacaaca aaataatttc acgcaacaaa ttaatgctgc tcaaaatcat gctgcgcttg
     9661 aaacaattaa gtctaacatt acggctttaa atactgcgat gacgaaatta aaagacagtg
     9721 ttgcggataa taatacaatt aaatcaggtc aaaattacac tgacgcaaca ccagctaata
     9781 aacaagccta tgataatgca gttaatgcgg ctaaaggtgt cattggagaa acgactaatc
     9841 caacgatgga tgttaacaca gtgaaccaaa aagcagcatc tgttaaatcg acgaaagatg
     9901 ctttagatgg tcaacaaaac ttacaacgtg cgaaaacaga agcaacaaat gcgattacgc
     9961 atgcaagtga tttaaaccaa gcacaaaaga atgcattaac acaacaagtg aatagtgcac
    10021 aaaacgtgca agcagtaaat gatattaaac aaacgactca aagcttaaat actgctatga
    10081 caggtttaaa acgtggcgtt gctaatcata accaagtcgt acaaagtgat aattatgtca
    10141 acgcagatac taataagaaa aatgattaca acaatgcata caaccatgcg aatgacatta
    10201 ttaatggtaa tgcacaacat ccagttataa caccaagtga tgttaacaat gctttatcaa
    10261 atgtcacaag taaagaacat gcattgaatg gtgaagctaa gttaaatgct gcgaaacaag
    10321 aagcgaatac tgcattaggt catttaaaca atttaaataa tgtacaacgt caaaacttac
    10381 aatcgcaaat taatggtgcg catcaaattg atgcagttaa tacaattaag caaaatgcaa
    10441 caaacttgaa tagtgcaatg ggtaacttaa gacaagctgt tgcagataaa gatcaagtga
    10501 aacgtacaga agattatgcg gatgcagata cagctaaaca aaatgcatat aacagtgcag
    10561 tttcaagtgc tgaaacaatt attaatcaaa cagctaatcc gacaatgtct gttgatgatg
    10621 ttaatcgtgc aacttcagct gttactacta ataaaaatgc attaaatggt gatgaaaaat
    10681 tagtacaatc taaaacagat gctgcaagag caattgatgc attaccacat ttaaataatg
    10741 cacaaaaagc agatgttaaa tctaaaatta atgctgcatc aaatattgct ggtgtaaata
    10801 ccgttaaaca acaaggtaca gatttaaata cagcgatggg taacttgcag ggtgcaatca
    10861 atgatgaaca aacgacgctt aatagtcaaa attatcaaga tgcgacacct agtaagaaaa
    10921 cagcatacac aaatgcggtg caagctgcga aagatatttt aaataaatca aatggtcaaa
    10981 ataaaacgaa agatcaagtt actgaagcga tgaatcaagt gaattcggct aaaaataact
    11041 tagatggtac gcgtttatta gatcaagcga agcaaacagc gaaacagcag ttaaataata
    11101 tgacgcattt aacaactgca caaaaaacga atttaacaaa tcaaattaat agtggtacta
    11161 ctgttgctgg tgttcatacg gttcaatcaa atgccaacac attagatcaa gcgatgaata
    11221 cgttaagaca aagtattgct aacaatgatg cgactaaagc aagtgaagat tacgtagatg
    11281 ctaataatga taagcaaaca gcatataaca acgcggtagc tgctgctgaa acgattatta
    11341 atgcgaatag taatccagaa atgaatccaa gtacgattac acaaaaagca gagcaagtga
    11401 atagttctaa aacggcactt aacggtgatg aaaacttagc tacggcaaaa caaaatgcga
    11461 aaacgtactt aaacacatta acgagtatta cagatgctca aaagaacaat ttgattagtc
    11521 aaattagtag tgcgacaaga gtgagtggtg ttgatactgt aaaacaaaat gcacaacatt
    11581 tagatcaagc tatggctaac ttacaaaatg gtattaacaa cgaatctcaa gtgaaatcat
    11641 ctgagaaata tcgtgatgct gatacaaata aacaacaaga gtatgataat gctattactg
    11701 cagcgaaagc gattttaaat aaatcgacag gtccaaacac tgcgcaaaat gcagttgaag
    11761 cagcattgca acgtgttaat actgcgaaag atgcattgaa tggtgatgca aaattaattg
    11821 cagctcaaaa cgcagcgaaa caacatttag gtactttaac gcatatcact acagcacaac
    11881 gcaatgattt aacaaatcaa atttcacaag ctacaaactt agctggtgtt gaatcagtta
    11941 aacaaagtgc aaatagttta gatggcgcaa tgggtaactt acaaacggct atcaacgata
    12001 agtcaggaac attagcgagc caaaacttct tggatgctga tgagcaaaaa cgtaatgctt
    12061 acaatcaagc tatatcagct gccgaaacca ttttaaataa acaaactgga ccgaatacag
    12121 cgaaaacagc ggttgaacaa gcacttaata atgttaatag tgcgaaacat gcattaaatg
    12181 gtacgcaaaa cttaaataat gcgaaacaag cagcgattac agcaattaat ggcgcatctg
    12241 atttaaatca aaaacaaaaa gatgcattaa aagcacaagc taatggtgct caacgcgtat
    12301 ctaatgcaaa tgatgtacaa cgtaatgcga ctgaactgaa cacggcaatg ggtcaattac
    12361 aacatgccat cgcagataag acgaatacgt tagcaagcag taaatatgtc aacgccgata
    12421 gcactaaaca aaatgcttac acaactaaag ttaccaatgc tgaacatatt attagcggta
    12481 cgccaacggt tgttacaaca ccttcagaag taacagctgc agctaatcaa gtaaacagag
    12541 cgaaacaaga attaaatggt gacgaaagat tacgtgttgc aaaacaaaac gccaatactg
    12601 ctattgatgc attaacgcaa ttaaatactc ctcaaaaagc taaattaaaa gaacaagtgg
    12661 gacaagccaa tagattagaa gacgtacaat ctgttcaaac aaatggacaa tcattgaaca
    12721 atgcaatgaa aggcttaaga gatagtattg ctaacgaaac aacagtcaaa gcaagtcaaa
    12781 actatacaga cgcaagtccg aataaccaat caacatataa tagcgctgtg tcaaatgcga
    12841 aaggtatcat taatcaaact aacaatccaa ctatggatac tagtgcgatt acccaagcta
    12901 caacacaagt gaataatgct aaaaatggtt taaacggtgc tgaaaactta agaaatgcac
    12961 aaaacactgc taagcaaaac ttaaatacgt tatcacactt aacaaataac caaaaatctg
    13021 caatctcatc acaaattgat cgtgcaggtc atgtgagtga ggtaacagct gctaaaaatg
    13081 cagcaactga gttaaacgcg caaatgggca acttggaaca agctatccat gatcaaaaca
    13141 cagttaaaca aggtgttaac ttcactgatg cagataaagc taaacgtgat gcttatacaa
    13201 atgcggtaag cagagcagaa acaattctga ataaaacgca aggtgcaaat acgtctaaac
    13261 aagatgttga agcggctatt caaaatgtta caagtgctaa aaatgcattg aatggtgatc
    13321 aaaacgttac aaatgcgaag aatgcagcta aaaatgcatt aaataactta acgtcaatta
    13381 ataatgcaca aaaacgtgac ttaacaacta aaattgatca agcaacaaca gtagctggtg
    13441 ttgaagcggt atctaataca ggtacacaat tgaatacagc gatggctaac ttgcaaaatg
    13501 gtattaatga taaagcgaat actttagcga gcgaaaacta tcatgatgct gattcagata
    13561 agaaaactgc ttatactcaa gccgttacga acgcagaaaa tattttaaat aaaaatagtg
    13621 gatcaaattt agataaagct gccgttgaaa acgcgttgtc acaagtgaca aatgcgaaag
    13681 gtgccctaaa tggtaaccat aatttagagc aagctaaatc aaatgcaaac actactataa
    13741 acggccttca acatttaaca acagcacaaa aagataaatt gaaacaacaa gtgcaacaag
    13801 cacaaaatgt tgcaggtgta gatactgtta aatcaagtgc caacacatta aatggtgcta
    13861 tgggtacgtt aagaaatagc atacaagata acacagctac gaaaaatggc caaaactatc
    13921 ttgatgctac agaacgtaac aaaacaaact ataacaatgc tgttgatagt gctaatggtg
    13981 tcattaatgc aacaagcaat ccaaatatgg atgctaatgc aattaaccaa atcgctacac
    14041 aagtgacatc aacgaaaaat gcattagatg gtacacataa tttaacgcaa gcgaaacaaa
    14101 cagcaacaaa tgccatcgat ggtgctacta acttaaataa agcgcaaaaa gatgcgttaa
    14161 aagcacaagt tacaagtgcg caacgtgttg caaatgtaac aagtatccaa caaactgcaa
    14221 atgaacttaa tacagctatg ggtcaattac aacatggtat tgatgatgaa aatgcaacaa
    14281 aacaaactca aaaatatcgt gacgctgaac aaagtaagaa aactgcttat gatcaagctg
    14341 tagctgctgc gaaagcaatt ttaaataaac aaacaggttc caattcagat aaagcagcag
    14401 ttgaccgtgc attacaacaa gtaacaagta cgaaagatgc attgaatggg gatgataaac
    14461 tggcagaagc gaaagcggca gctagacaaa acttaggtac tttaaaccat attacgaatg
    14521 cacaacgtac tgcgttagaa ggtcaaatca atcaagcgac gactgttgat ggcgttaata
    14581 ctgtaaaaac aaatgccaat acattagacg gcgatatgaa tagcttacaa ggtgcaatca
    14641 atgataaaga tgcgacatta agaaatcaaa attatcttga tgcagatgaa tcaaaacgaa
    14701 atgcatatac gcaagctgtc acagcggctg aaggcatttt aaataaacaa acaggtggta
    14761 acacatctaa agcagacgtt gataatgcat taaatgcagt tacaagagcg aaagcggctt
    14821 taaatggtgc tgaaaactta agaaatgcga aaacttcagc aacaaatacg attaatggtt
    14881 tacctaactt aacacaatta caaaaagaca acttgaagca tcaagttgaa caagcgcaaa
    14941 atgtagttgg tgtaaatggt gttaaagata aaggtaatac attaaatact gccatgggtg
    15001 cattacgtac aagtatccaa aatgataata cgacgaaaac aagtcaaaat tatcttgatg
    15061 catctgatag caacaaaaat aattacaata ctgctgtaaa taatgcaaat ggtgttatta
    15121 atgcaacgaa caatccaaat atggatgcta atgcgattaa tgacatggca aatcaagtca
    15181 atacaacaaa agcagcgtta aatggtgcac aaaacttagc tcaagctaaa acaaatgcga
    15241 cgaacacaat taacaacgcg caagacttaa accaaaaaca aaaagatgca ttaaaaacac
    15301 aagttaacaa tgcacaacgt gtatctgatg caaataacgt tcaacataca gctactgaat
    15361 tgaacggtgc gatgacagca cttaaagcag ctattgcgga taaagaaaga acaaaagcaa
    15421 gcggtaatta tgtcaatgct gatcaagaaa aacgtcaagc gtatgattca aaagtgacta
    15481 acgctgaaaa tatcattaat ggtacaccaa atgcgacatt aacagtcaat gacgtaaata
    15541 gtgcggcatc acaagtcaat gcggctaaaa cagcattaaa tggtgataac aacttacgtg
    15601 tagcgaaaga gcatgctaac aatacaattg acggcttagc acaattgaat aatgtacaaa
    15661 aagcaaaatt aaaagaacaa gttcaaagtg caactacatt agatggtgtt caaactgtta
    15721 aaaatagttc tcaaacgttg aatacagcga tgaaaggctt aagagatagt attgcgaatg
    15781 aagcaacgat taaagcaggt caaaactaca ctgacgcaag tccaaataat cgtaacgagt
    15841 acgacagcgc agttactgca gcaaaagcaa tcattaatca aacatcgaac ccaacgatgg
    15901 aaccaaatac tattacgcaa gcaacatcac aagtgacaac taaagaacat gcattaaatg
    15961 gtgcgcaaaa cttagctcaa gctaagacaa cagcgaaaaa caacttgaat aacttaacat
    16021 caattaacaa tgcacaaaaa gatgcgttaa cgcgtaacat tgatggtgca actacagtag
    16081 ctggtgtaaa tcaagaaact gcaaaagcaa cagaattaaa taacgcaatg cacagtttac
    16141 aaaatggtat caatgatgag acacaaacaa aacaaactca gaaataccta gatgctgagc
    16201 caagtaagaa atcagcttat gatcaagcag taaatgcagc aaaagcaatt ttaacaaaag
    16261 ctagtggtca aaatgtagac aaagcagcag ttgaacaagc attacaaaat gtgaacagta
    16321 cgaagacggc gttgaacggt gatgcgaaat taaatgaagc taaagctgct gcgaaacaaa
    16381 cgttaggtat attaacacac attaataatg cacaacgtaa tgcgttagat aatgaaatta
    16441 cacaagcaac aaatgttgaa ggtgttaata cagttaaagc caaagcgcaa caattagatg
    16501 gtgctatggg tcaattagaa acatcaattc gtgataaaga cacgacgtta caaagtcaaa
    16561 attatcaaga tgctgatgat gctaaacgaa cggcttattc tcaagcagta aatgcagcag
    16621 caactatttt aaataaaaca gctggaggaa atacacctaa agcagatgtc gaaagagcaa
    16681 tgcaagctgt tacacaagcc aatactgcat taaacggtat tcaaaactta gaacgtgcga
    16741 aacaggctgc gaacacagcg attacaaatg cttcggactt aaatacaaaa caaaaagaag
    16801 cattgaaagc acaagtaaca agtgcaggac gcgtatctgc agcaaatggt gttgaacata
    16861 ctgcgactga attaaatact gcgatgacag ctttaaaacg tgccattgct gataaagctg
    16921 acacaaaagc tagtggtaat tatgtcaatg ctgatgcgaa taaacgccaa gcatatgatg
    16981 aaaaagtgac agctgcagaa catatcgtta gtggtacacc aacaccaacg ttaacaccat
    17041 cagatgttac aaatgcagca acgcaagtaa cgaatgcgaa gacgcagtta aacggtaatc
    17101 ataatttaga agtagcgaaa caaaatgcta acacagcaat tgatggttta acttctttaa
    17161 atggtccgca aaaagcaaaa cttaaagaac aagtgggtca agcgacgacg ttgccaaatg
    17221 ttcaaactgt tcgtgataat gcacaaacat taaacactgc aatgaaaggt ctacgagata
    17281 gcattgcgaa tgaagcaacg attaaagcag gtcaaaacta cacagatgca agtcaaaaca
    17341 aacaaaatga ctacaacaat gcagtcactg cagcaaaagc aatcattggt caaacaacta
    17401 gtccatcaat gattgcgcaa gaaattaatc aagcgaaaga ccaagtgaca gctaaacaac
    17461 aagcgttaaa cggtcaagaa aacttaagaa ctgcgcaaac aaatgcgaag caacatttga
    17521 atggcttaag tgacttaact aatgcacaaa aagatgcagc gaaacgccaa atcgaaggtg
    17581 caacgcatgt taatgaagta acacaagcgc aaaataatgc ggacgcatta aatacagcta
    17641 tgacgaactt gaaaaatggt attcaagatc aaaatacgat taagcaaggt gttaacttca
    17701 ctgatgcaga tgaagcgaaa cgtaatgcat atacaaatgc agtgacgcaa gctgaacaaa
    17761 ttttaaataa agcacaaggt ccaaatactg caaaagacgg tgtcgaaact gcgttacaaa
    17821 atgtacaacg tgctaaaaac gaattgaacg gtaatcaaaa tgttgcgaac gctaagacaa
    17881 ctgcgaaaaa tgcattgaat aaccttacat caattaataa tgcacaaaaa gcagcattga
    17941 aatcacaaat tgaaggtgcg acaacagttg caggtgtaaa tcaagtgtct acaatggcat
    18001 ctgaattaaa tactgcaatg agcaacttac aacgtggtat taatgacgaa gcagctacaa
    18061 aagcagctca gaaatatact gaagcagata gagataaaca aactgcatac aatgatgctg
    18121 taacagcagc taaaacgtta ttagataaaa cagctggttc aaatgacaat aaagtagccg
    18181 ttgaacaagc attacaacgt gtgaatactg ctaaaacagc attaaatggt gacgcgcgat
    18241 taaatgaagc gaagaacaca gctaaacaac aattagcgac aatgtcacat ttaactaatg
    18301 ctcaaaaagc aaacttaaca gaacaaattg aacgtggtac aactgttgct ggtgttcaag
    18361 gcatccaagc aaatgctggt actttaaatc aagcaatgaa tcaattaaga caaagtattg
    18421 cttctaaaga tgcgactaaa tcaagcgaag attatcaaga cgcgaatgca gatttacaaa
    18481 atgcatacaa tgatgcggta actaatgctg aaggtattat tagtgcaacg aataaccctg
    18541 aaatgaatcc tgatacaatt aaccaaaaag cgagccaagt gaacagtgcg aagtctgcat
    18601 tgaacggtga tgaaaaatta gcagcagcaa aacaaactgc gaaatcagat atcggtcgtt
    18661 tgacagactt gaacaatgca caacgaactg cggcaaatgc tgaagtggat caagcaccaa
    18721 atcttgcagc tgtcacagcg gctaaaaata aagcaacatc gttaaacaca gcgatgggta
    18781 atttgaaaca tgcacttgct gaaaaggata atacgaaacg tagtgtcaat tacacagatg
    18841 cggatcaacc aaaacaacaa gcgtatgata ctgcagttac acaagcagaa gcaattacta
    18901 atgcaaatgg cagtaacgcg aatgaaacac aagttcaagc agcgcttaac caattgaatc
    18961 aagctaaaaa cgacttgaat ggtgataata aagttgctca agcgaaagaa acagcaaaac
    19021 gtgcattagc ttcatatagt aacttgaata acgcgcaatc aactgcagca actagtcaaa
    19081 ttgacaatgc aacgacagta gcagacgtaa ctgctgcaca aaatactgct aatgaattaa
    19141 atacagcaat gggtcaactt caaaatggta ttaatgacca aaacactgtt aaacaacaag
    19201 tgaactttac agatgctgac caaggtaaga aagatgctta cacaaatgct gttacgaatg
    19261 ctcaaggtat tttagataaa gcaaacggtc aaaatatgac aaaagcacaa gttgaagctg
    19321 cattaaatca agtaacgact gctaagaatg ctttaaacgg tgatgcaaat gtaagacaag
    19381 caaaatcaga tgcgaaagca aacttaggta cattaacaca cttaaataat gcacaaaaac
    19441 aagatttaac atcacaaatc gaaggtgcaa caacagtcaa cggtgtaaat agtgttaaaa
    19501 cgaaagcaca agacttagat ggtgcaatgc aacgattaga gtcagcaatc gcaaataaag
    19561 atcaaactaa agcgagcgaa aactacattg acgcagatcc aactaagaaa acagcatttg
    19621 ataatgccat cacacaagct gaatcttact taaataaaga tcatggtacg aataaagata
    19681 agcaagctgt tgaacaagca attcaaagtg taacgtctac tgaaaatgct ttgaacggtg
    19741 acgcgaactt acaatgcgct aaaactgaag ctacacaagc tatcgataac ttgacacaat
    19801 tgaatacacc gcaaaaaaca gcattgaaac aacaagtgaa tgctgcacaa cgcgtatcag
    19861 gtgtaactga tctgaaaaat agtgctacat cacttaataa tgcgatggat caattaaaac
    19921 aagcaattgg tgatcatgac acaattgtag ctggtggtaa ttacactaac gcaagtcctg
    19981 ataaacaagg tgcttacact gatgcatata atgctgcgaa gaatatcgta aatggttcac
    20041 ctaatgtgat tacaaatgca gcagatgtta ctgcggcaac acaacgtgtc aataatgctg
    20101 aaacaagttt aaatggtgat acaaacttag caactgcgaa gcaacaagct aaagatgcat
    20161 tacgtcaaat gacacattta tctgatgcac aaaaacaaag tattactggt caaattgata
    20221 gcgcgacaca agtaactggt gtacaaagtg tgaaagacaa tgcaacaaat cttgacaatg
    20281 caatgaatca acttcgaaat agtattgcga ataaagatga agtaaaagcg agtcaaccat
    20341 atgttgatgc agatacagat aaacaaaatg catacaatac agcagttaca agtgctgaaa
    20401 atatcattaa tgcaacgagt cagccaacac ttgatccatc tgcagtaaca caagcagcta
    20461 atcaagtgaa cactaacaaa actgcgctta atggtgcgca aaacttagca aataaaaagc
    20521 aagaaacaac tgctaacatc aaccgattaa gtcatttaaa caatgctcaa aagcaagatt
    20581 taaatacaca agtgacaaat gcaccaaata ttagcacagt aaatcaagtg aaaactaaag
    20641 ctgaacaatt agatcaagca atggaacgtt taatcaacgg aatccaagac aaagatcaag
    20701 tgaaacaaag tgttaacttt acagatgcag atccagaaaa acaaacagca tacaacaatg
    20761 cggtaactgc tgctgaaaat attattaatc aagcaaatgg tacaaatgcg aaccaatcac
    20821 aagttgaagc agcactttca actgtaacaa ctactaaaca agcgttgaat ggtgatagaa
    20881 aagtaacaga tgctaaaaac aatgcaaacc aaacattatc tacgttagat aacttaaaca
    20941 atgcacaaaa aggtgctgtt actggaaaca tcaatcaagc gcacactgta gctgaagtaa
    21001 cgcaagccat tcaaaccgct caggaactga atacagcgat gggtaacttg aaaaatagct
    21061 tgaatgataa agacactaca cttggcagtc aaaactttgc agatgcagat ccagagaaga
    21121 aaaatgcata caatgaagcg gttcgtaatg ctgaaaatat tttaaataaa tctacaggta
    21181 cgaacgtgcc taaagatcaa gttgaagcag ctatgaatca agtgaatact acaaaagcag
    21241 cgcttaatgg tactcaaaac cttgaaaaag cgaaacaaca cgcaaataca gcaattgacg
    21301 gtttaagcca tttaacaaat gcacaaaaag aggcattaaa acaattggta caacaatcga
    21361 ctactgttgc agaagcacaa ggtaatgaac aaaaagcaaa caatgttgat gcagcaatgg
    21421 acaaattacg tcaaagtatt gcagataatg cgacaacaaa acaaaaccaa aattatactg
    21481 atgcaagtcc gaataaaaag gatgcgtaca ataatgttgt cacaactgca caaggtatta
    21541 ttgatcaaac tacaaaccct tcattagatc cgactgttat caatcaagct gctggacaag
    21601 taagcacgtc taaaaatgct ttaaatggta atgaaaactt agaggcagcg aagcaacaag
    21661 caacgcaatc tttaggttca ttagacaact taaataatgc gcaaaaacaa gctgttacta
    21721 atcaaattaa tggcgcgcat actgttgatg aagcaaatca aattaagcaa aatgcgcaaa
    21781 acttaaatac tgcgatgggt aacttgaaac aagcgatagc tgataaagat gctacgaaag
    21841 caacagttaa cttcactgat gcagatcaag caaaacaaca agcatataac actgcagtta
    21901 caaatgctga aaatatcatt tcaaaagcta atggtggtaa tgcaacacaa actgaagttg
    21961 aacaagcaat ccaacaagta aatgcagcaa aacaagcatt aaatggtaat gccaacgttc
    22021 aacatgcaaa agacgaagca acagcattaa ttaataactc taatgatctt aaccaagcac
    22081 agaaagatgc attaaaacaa caagtacaaa atgcaactac tgtagctggt gtaaacaatg
    22141 ttaaacaaac ggcgcaagag ttaaacaatg cgatgacaca attaaaacaa ggcattgcag
    22201 ataaagaaca aacaaaagct gatggtaact ttgtcaatgc agattctgac aagcaaaatg
    22261 catataatca agcagtagcg aaagctgaag cattaattag tggtacgcct gatgttgtcg
    22321 ttacacctag cgaaattact gcagcgttaa ataaagttac gcaagctaaa aatgatttaa
    22381 atggtaatac aaacttagca acggcgaaac aaaatgttca acatgctatt gatcaattgc
    22441 caaacttaaa ccaagcgcaa cgtgatgaat acagcaaaca aatcacgcaa gcaacacttg
    22501 taccaaacgt caatgctatt caacaagcgg caacaacgct taatgacgcg atgacacaat
    22561 tgaaacaagg tattgcgaat aaagcacaaa ttaaaggtag cgagaactat cacgatgctg
    22621 atactgacaa gcaaacagca tatgataatg cagtaacaaa agcagaagaa ttgttaaaac
    22681 aaacaacaaa tccaacaatg gatccaaata caattcaaca agcattaact aaagtgaatg
    22741 acacaaatca agcacttaac ggtaatcaaa aattagctga tgccaaacaa gatgctaaga
    22801 caacacttgg tacactagat catttaaatg atgctcaaaa acaagcgcta acaactcaag
    22861 ttgaacaagc accagatatt gcaacagtta ataatgttaa gcaaaatgct caaaatctga
    22921 ataatgctat gactaactta aacaatgcat tacaagataa aactgagaca ttaaatagca
    22981 ttaactttac tgatgcagat caagctaaga aagatgatta tactaatgcg gtttcacatg
    23041 cagaaggtat tttatctaaa gcaaatggca gcaatgcaag tcaaactgaa gtggaacaag
    23101 cgatgcaacg tgtgaacgaa gcgaaacaag cattgaatgg taatgacaat gtacaacgtg
    23161 caaaagatgc agcgaaacaa gtaattacaa atgcaaatga tttaaatcaa gcgcaaaaag
    23221 atgcattaaa acaacaagtc gatgctgcgc aaactgttgc aaatgtaaac acgattaagc
    23281 aaacagcaca agatttaaat caagcaatga cacaattgaa acaaggtatt gcagataaag
    23341 accaaactaa agcaaatggt aactttgtca atgctgatac tgataagcaa aatgcatata
    23401 acaatgcggt agcgcatgct gaacaaatca ttagtggtac accaaatgca aacgtggatc
    23461 cacaacaagt ggctcaagcg ttacaacaag tgaatcaagc taagggtgat ttaaacggta
    23521 accataactt acaagttgct aaagacaatg caaatacagc cattgatcag ttaccaaact
    23581 taaatcaacc acaaaaaaca gcattaaaag accaagtgtc gcatgcagaa cttgttacag
    23641 gtgttaatgc tattaagcaa aatgctgatg cgttaaataa tgcaatgggt acgttgaaac
    23701 aacaaattca agcgaatagt caagtaccac aatcagttga ctttacacaa gcggatcaag
    23761 acaaacaaca agcttataac aatgcagcta accaagcgca acaaatcgca aatggcacac
    23821 caacacctgt attggcgcct gatacagtaa caaaagcagt tacaactatg aatcaagcga
    23881 aagatgcatt aaacggtgat gaaaaattag cgcaagcgaa acaagatgct ttagcaaatc
    23941 ttgatacgtt acgtgactta aatcaaccac aacgtgatgc attacgaaac caaatcaatc
    24001 aagcacaagc tttagctaca gttgaacaaa ctaaacaaaa tgcacaaaat gtgaatacag
    24061 caatgggtaa cttgaaacaa ggtattgcaa ataaagatac tgtgaaagca agtgagaact
    24121 accacgatgc tgatgtcgat aagcaaacag catatacaaa tgcagtgtct caagcggaag
    24181 gtattatcaa tcaaacgaca aatccaacgc ttaacccaga tgacattact cgtgcattaa
    24241 ctcaagtgac tgatgctaaa aatagcttaa acggtgaagc taaattagcc actgaaaagc
    24301 aaaatgctaa agatgccgta agtggaatga cgcatttaaa cgatgctcaa aaacaagcat
    24361 taaaaggtca aatcgatcaa tcgcctgaaa ttgctacagt gaaccaagtt aaacaaacag
    24421 caacgagcct agatcaagca atggatcaat tatcacaagc tattaatgat aaagatcaaa
    24481 tattagcgga cggtaattac ttaaatgcag atcctgacaa acaaaatgcg tataaacagg
    24541 cagtagcaaa agctgaagca ttattgaata aacaaagtgg tactaatgaa gtacaagcac
    24601 aagttgaaag catcactaat gaagtgaacg cagcgaaaca agcattaaat ggtaatgaca
    24661 atttggcaaa tgcaaaacaa caagcaaaac aacaattggc gaacttaaca cacttaaatg
    24721 atgcacaaaa acaatcattt gaaagtcaaa ttacacaagc gccacttgtt acagatgtca
    24781 ctacgattaa tcaaaaagca caaacgttag atcatgcgat ggaattatta agaaatagtg
    24841 ttgcggataa tcaaacgaca ttagcgtctg aagattatca tgatgcaact gcgcaaagac
    24901 aaaatgacta taacaaagct gtaacagctg ctaataatat cattaatcaa actacatcgc
    24961 ctacgatgaa tccagatgat gttaatggtg caacgacaca agtgaataat acgaaagttg
    25021 cattagatgg tgatgaaaac cttgcagcag ctaaacaaca agcaaacaac agacttgatc
    25081 aattagatca tttgaataat gcgcaaaagc aacagttaca atcacaaatt acgcaatcat
    25141 ctgatattgc tgcagttaat ggtcacaaac aaacagcaga atctttaaat actgcgatgg
    25201 gtaacttaat taatgcgatt gcagatcatc aagccgttga acaacgtggt aacttcatca
    25261 atgctgatac tgataaacaa actgcttata atacagcggt aaatgaagca gcagcaatga
    25321 ttaacaaaca aactggtcaa aatgcgaacc aaacagaagt agaacaagct attactaaag
    25381 ttcaaacaac acttcaagcg ttaaatggag atcataattt acaagttgct aaaacaaatg
    25441 cgacgcaagc aattgatgct ttaacaagct taaatgatcc tcaaaaaaca gcattaaaag
    25501 accaagttac agctgcaact ttagtaactg cagttcatca aattgaacaa aatgcgaata
    25561 cgcttaacca agcaatgcat ggtttaagac agagcattca agataacgca gcaactaaag
    25621 caaatagcaa atatatcaac gaagatcaac cagagcaaca aaactatgat caagctgttc
    25681 aagccgcaaa taatattatc aatgaacaaa ctgcaacatt agataataat gcgattaatc
    25741 aagtagcggc aactgtgaat acaacgaaag cagcattaca tggtgatgtg aaattacaaa
    25801 atgataaaga tcatgctaaa caaacggtta gccaattagc acatctaaac aatgcacaaa
    25861 aacatatgga agatacgtta attgatagtg aaacaactag aacagcagtt aagcaagatt
    25921 tgactgaagt acaagcatta gatcaactta tggatgcatt acaacaaagt attgctgaca
    25981 aagatgcaac acgtgcgagc agtgcatatg tcaatgcaga accgaataaa aaacaagcct
    26041 atgatgaagc agttcaaaat gctgagtcta tcattgcagg attaaataat ccaactatca
    26101 ataaaggtaa tgtatcaagt gcgactcaag cagtaatatc atctaaaaat gcattagatg
    26161 gtgttgaacg attagctcaa gataagcaaa ctgctggaaa ttctctaaat catttagatc
    26221 aattaacacc agctcaacaa caagcgctag aaaatcaaat taataatgca acaactcgtg
    26281 ataaagtggc tgaaatcatt gcacaagcgc aagcattaaa tgaagcgatg aaagcattaa
    26341 aagaaagtat taaggatcaa ccacaaactg aagcaagtag taaatttatt aacgaggatc
    26401 aagcgcaaaa agatgcatat acgcaagcag tacaacacgc gaaagatttg attaacaaaa
    26461 caactgatcc tacattagct aaatcaatca ttgatcaagc gacacaggca gtgactgatg
    26521 ctaaaaacaa tttacatggt gatcaaaaac tagctcaaga taagcaacgt gcaacagaaa
    26581 cgttaaataa cttgtctaac ttgaatacac cacaacgtca agcacttgaa aatcaaatca
    26641 ataatgcagc aactcgtggt gaagtagcac aaaaattaac tgaagcacaa gcacttaacc
    26701 aagcaatgga agctttacgt aatagcattc aagatcaaca acaaacagaa tctggtagca
    26761 agtttattaa tgaagataaa ccgcaaaaag atgcttacca agcagcagtt caaaatgcaa
    26821 aagatttaat taaccaaaca ggtaatccaa cgcttgataa agcacaagtt gaacaattga
    26881 cacatgcttt taaacaagct aaagataacc tacacggtga tcaaaaactt gcagacgata
    26941 aacaacatgc ggttactgat ttaaatcaat taaatggttt gaataatccg caacgtcaag
    27001 cacttgaaag ccaaataaac aacgcagcaa ctcgtggcga agtagcgcaa aaattagctg
    27061 aagcaaaagc gcttgatcaa gcaatgcaag cattacgaaa tagtattcaa gatcaacaac
    27121 aaacggaagc gggtagcaag tttatcaatg aagataaacc gcaaaaagat gcttaccaag
    27181 cagcagttca aaatgcaaaa gatttaatta accaaacagg taatccaaca ctcgacaaat
    27241 cacaagtaga acaattaaca caagcagtaa caactgcaaa agataatcta catggtgatc
    27301 aaaaacttgc tcgtgatcaa caacaagcag taacaactgt aaatgcattg ccaaacttaa
    27361 atcatgcaca acaacaaaca ttaactgatg ctataaatgc agcgcctaca agaacagagg
    27421 ttgcacaaca tgttcaaact gctactgaac ttgatcacgc gatggaaaca ttgaaaaata
    27481 aagttgatca agtgaataca gataaggctc aaccaaatta cactgaagcg tcaactgata
    27541 aaaaagaagc agtagatcaa gcgttacaag ctgcacaaag cattacagat ccaactaatg
    27601 gttcaaatgc gaataaagac gctgtagaac aagcattaac taagcttcaa gaaaaagtga
    27661 atgagttaaa tggtaatgag agagtcgctg aagctaaaac acaagcgaaa caaactattg
    27721 accaattaac acatttaaat gctgatcaaa ttgcaactgc taaacaaaat attgatcaag
    27781 cgacgaaact tcaaccaatc gctgaattag tagatcaagc aacgcaattg aaccaatcaa
    27841 tggatcaatt acaacaagca gttaatgaac atgctaacgt tgagcaaact atagattaca
    27901 cacaagcaga ttcagataag caaaaggctt ataaacaagc gattgctgat gctgaaaatg
    27961 tattgaaaca aaatgcgaat aagcaacaag tggatcaagc acttcaaaat attttaaatg
    28021 caaaacaagc attaaatggt gatgaacgtg tagcacttgc taaaacaaat ggtaaacatg
    28081 acatcgacca attgaatgca ttaaacaatg ctcaacaaga tggatttaaa ggtcgcatcg
    28141 atcaatcaaa cgatttaaat caaatccaac aaattgtaga tgaggctaag gcacttaatc
    28201 gtgcaatgga tcaattgtca caagaaatca ctggcaatga aggacgcacg aaaggtagca
    28261 cgaactatgt caatgcagat acacaagtca aacaagtata tgatgaagcg gttgataaag
    28321 cgaaacaagc acttgataaa tcgtctgggc aaaacttaac tgcagaacaa gttatcaaat
    28381 taaatgatgc agtcactgca gctaagaaag cattaaatgg tgaagaaaga cttaataatc
    28441 gtaaagctga agcattacaa agattggatc aattaacaca tctaaacaat gctcaaagac
    28501 aattagcaat ccaacaaatt aataatgctg aaacgctaaa taaagcatct cgagcaatta
    28561 atagagcaac taaattagat aatgcaatgg gtgcagtaca acaatatatt gacgaacagc
    28621 accttggtgt tatcagcagc acaaattaca tcaatgcaga tgacaatttg aaagcaaatt
    28681 atgataatgc aattgcgaat gcagcacatg agttagataa agtgcaaggt aatgcaattg
    28741 caaaagctga agcagagcaa ttgaaacaaa atattatcga tgctcaaaat gcattaaatg
    28801 gagaccaaaa ccttgcaaat gccaaagata aagcaaatgc gtttgttaat tcgttaaatg
    28861 gattaaatca acagcaacaa gatcttgcac ataaagcaat taacaatgcc gatactgtat
    28921 cagatgtaac agatattgtt aataatcaaa ttgacttaaa tgatgcaatg gaaacattga
    28981 aacatttagt tgacaatgaa attccaaatg cagagcaaac tgtcaattac caaaacgctg
    29041 acgataatgc taaaacaaac ttcgatgatg ccaaacgtct agcaaataca ttgctaaata
    29101 gtgataacac aaatgtgaat gatatcaatg gcgcaatcca agcagtcaat gatgcaatcc
    29161 ataatcttaa tggtgatcaa cgactacaag atgctaaaga caaggcaatt caatcaatta
    29221 atcaagcttt agctaataag ctaaaagaaa tcgaagcttc aaatgcgacg gatcaagaca
    29281 agcttattgc gaaaaataaa gcagaagaat tggcaaacag catcatcaac aacattaata
    29341 aagcaacaag taatcaggct gtatctcaag ttcaaacagc aggcaaccac gcgattgaac
    29401 aagtgcatgc taatgaaata ccaaaagcaa aaattgatgc caataaagac gttgataagc
    29461 aagttcaagc attaattgac gaaattgatc gaaatccaaa tctaacagat aaggaaaaac
    29521 aagcacttaa agatcgtatt aatcaaatac ttcaacaagg tcataacgac attaacaatg
    29581 cgctgactaa agaagaaatt gaacaagcta aagcacaact tgcgcaagca ttacaagaca
    29641 tcaaagattt agtgaaagct aaagaagatg cgaaacaaga tgttgataaa caagttcaag
    29701 cattaattga cgaaatcgat caaaatccaa atctaacaga taaggaaaaa caagcactta
    29761 aagatcgtat taatcaaata cttcaacaag gtcataacgg cattaacaat gcgatgacta
    29821 aagaagaaat tgaacaagcc aaagcacaac ttgcacaagc attaaaagaa attaaagatt
    29881 tagtgaaagc taaagaaaat gcgaaacaag atgttgataa acaagttcaa gcattaattg
    29941 acgaaatcga tcaaaatcca aatctaacag ataaggaaaa acaagcgctt aaagatcgaa
    30001 tcaatcaaat actgcaacaa ggtcataacg acattaacaa tgcgatgact aaagaagaaa
    30061 ttgaacaagc caaagcacaa cttgcacaag cattacaaga catcaaagat ttagtgaaag
    30121 ctaaagaaga tgcgaaaaat gcaataaaag ccttagctaa tgcgaagcgt gatcaaatca
    30181 attcaaatcc agatttaaca cctgagcaaa aagcaaaagc gctcaaagaa attgacgaag
    30241 ctgaaaaacg agcactacaa aacgttgaga atgctcaaac tatagatcaa ttaaatcgag
    30301 gattaaactt aggtttagat gacattagaa atacacatgt atgggaggtt gatgaacaac
    30361 ctgctgtaaa tgaaattttt gaagcaacac ctgagcaaat cctagttaat ggtgaactca
    30421 ttgtacatcg tgatgacatc attacagaac aagatattct tgcacacata aacttaattg
    30481 atcagctttc agcagaagtt attgatacac catcaactgc aacgatttct gatagcttaa
    30541 cagcaaaagt tgaagttaca ttgcttgatg gatcaaaagt gattgttaat gttcctgtaa
    30601 aagttgtaga aaaagaattg tcagtagtca aacaacaggc aattgaatca atcgaaaatg
    30661 cggcacaaca aaagattgat gaaatcaata atagtgtgac attaacactg gaacaaaaag
    30721 aagctgcaat tgcagaagtt aataagctta aacaacaagc aattgatcat gttaacaatg
    30781 cacctgatgt tcattcagtt gaagaaattc aacaacaaga acaagcgtat attgaacaat
    30841 ttaatccaga acaatttacg attgaacaag caaaatcaaa tgcaattaaa tcgattgaag
    30901 atgcaattca acatatgatt gatgaaatca aagctcgtac tgatctaaca gataaagaga
    30961 agcaagaagc tattgctaag ttaaatcaat taaaagaaca agcaattcaa gcgattcaac
    31021 gtgcgcaaag catcagtgaa ataactgagc aattggaaca atttaaagct caaatgaaag
    31081 cagctaatcc aacagcaaaa gaactagcta aacgcaagca agaagctatt agtagaatta
    31141 aagacttttc aaatgaaaaa ataaatagta ttcgaaatag tgaaattggc acagctgatg
    31201 aaaaacaagc agcaatgaat caaattaacg aaattgtgct tgaaacaatt agagatatta
    31261 ataatgcgca tacattacag caagttgagg ctgcattgaa caatggtatt gctcgaattt
    31321 cagcagtaca aattgtaata tctgatcgtg ctaaacaatc gtcaagtact ggaaatgaat
    31381 ctaatagcca tttaacaatt ggttatggaa ctgcaaatca tccatttaac agttcgacta
    31441 ttggacataa aaagaaactt gatgaagatg atgacattga tccacttcat atgcgtcact
    31501 ttagtaataa tttcggtaat gttattaaaa acgctattgg tgtggtgggt atctctggct
    31561 tactagctag tttctggttc ttcattgcca aacgtcgtcg taaagaagat gaagaggaag
    31621 aattagaaat aagagataat aataaagatt caataaaaga gactttagac gatacaaaac
    31681 atttaccact tttatttgcg aaacgtcgca gaaaagaaga tgaagaagat gttactgttg
    31741 aagaaaaaga ttcgctaaat aatggcgagt cactcgataa agttaaacat acgccgttct
    31801 tcttaccaaa acgtcgtcgt aaagaagatg aagaagatgt ggaagttaca aatgaaaaca
    31861 cagatgaaaa agtgttgaaa gataacgaac attcaccact cttattcgca aaacgacgca
    31921 aagataaaga ggaagatgtt gaaacaacaa ctagtattga atctaaagat gaggacgttc
    31981 ctttattatt ggctaaaaag aaaaatcaaa aagataacca atccaaagac aaaaagtcag
    32041 catcaaaaaa tacttctaaa aaggtagcag ctaaaaagaa gaaaaagaaa tctaagaaaa
    32101 ataaaaaata atttgtttct ttgataaata gaggagcacc gattgacatc acatcagtcg
    32161 gtgctccttt tatttattct ttttaattaa tttatacaat gcctgttgag cgtgttgatt
    32221 cgcttctttg ttttgttctc tcggtatcca tttaacaaat aataaatcaa aatctttttc
    32281 aaatatttct atttgatcaa aataaggttt gaaatttgcg tttttcacat aaccagcttc
    32341 aatgctatct gcaattagct ttgagtctgt atataatagt gcgttttgaa catttaattc
    32401 acgtgcatgt tctagtgcat aaatacatgc agcccattct gcagtgtggt tatccatttc
    32461 gcctaactca tgtgtatatg tataatgctg cttatcttct ttgattacaa tggcacatgt
    32521 acttatgcct ggatttcctt tcgtcgcagc atcaaaattt attttcgcca taataaacct
    32581 actttctatt caatacttag ttaaagttac tattactgta atacaaaata tgttgggtaa
    32641 tccattaaaa aacacgcatc acttaaataa gtaacacgtg tttaaaatac tcgctgattc
    32701 aaagatgatt ttctaatacg tagtactgta atatacttcc taaaaaaatc atcttcaggc
    32761 tgggacataa atcaatgttc tatgctctac gaagttatat tggcagtagt tgactgaacg
    32821 aaaatgcgct tgtaacaagc ttttttcaat tctagtcagg ggccccaaca cagaagctga
    32881 cgaaaagtca gcttacaata atgtgcaagt tggggatgga ccccaacaaa gagaaattgt
    32941 attcccaatt tctacagaca atgcaagttg gggtgggacg acgaaataaa ttttgcgaaa
    33001 atatcatttc tgtcccactc ccttaaaact tattcttttg tgtagtaagt gcgttaatag
    33061 ccttgatcta acttatcaat cttaccttta cgataaaatg atttagcaat atatccaaat
    33121 ggtacattga aaactgttga agctaatttt aatacgtaag ttgtaataaa tatttcaaat
    33181 acaactgtac caggtaaact tccgataaaa gcgatagcta caaataaagc tgtatcaatt
    33241 attgagctta aaaatgtact accatatgca cggatgaaaa acgttttatc agaactaaat
    33301 acttttttaa ttagtgaaaa gataaataca tcaatatgtt gaccaataat atatgcgaca
    33361 attgagccta aagcaatacg tggcacaaca tcaaagattg cgtgtaatgc tttttgtgcc
    33421 atatcttctg gtgcaggaat aaaatgtaat gacaattgca taacaataat cataattaat
    33481 gttgatgaaa agcctaacca aactgctctt tttgcaactc tacgcccata aatatcattt
    33541 aaaatatctg ttgctaaata aatagaagca aacatgacat tacctaaagt tgctgaaata
    33601 ccaaagattt ctacagtttt aatcacttgt atgttggcaa tgattgtgcc aattgcaacc
    33661 catgcaatta aaccttgttt accaaaaaag cgatacataa gtaccataag tacgaacgtt
    33721 gcaataaacg taactagtcc taaaatttca ttatacatat taaaatgtcc tcctaaattt
    33781 tgatcatgcg ggtgtttaga aaccgctcaa taaataactt actcatttta ctgaaaaatc
    33841 gtttgcgatg caatagcatt tgaatataaa tacattttac gtatagaatt gtaaaaggtt
    33901 tcattcaaat cttagggtca aaaatgttat aatattttta tgtcaaattt aaaacagtaa
    33961 cacttattta caaggttgca atattttgaa gtaataaagg aagtgtcgcg tattttaact
    34021 ttttcagagc aaaatgcact cgtgaaaata gatgatttaa tgaatactta ttgcaatcaa
    34081 tgtccaatca aaactcgtct gcgtaaatta gaggggaaaa cgaaggcgca tcatttttgt
    34141 atcaatgagt gttcaatagg gaaagaaata aaacaattag gaaatgaact tcaataggag
    34201 gaagtcaaat gaaaattata tctatatcag aaacaccgaa ccacaacaca atgaagatta
    34261 cacttagtga aagcagagaa ggtatgacat cagatacgta tactaaagtt gatgattcac
    34321 agccagcatt tattaatgac atcttaaagg ttgaaggcgt taaatcaatt ttccatgtta
    34381 tggactttat ttcagtagat aaagaaaatg acgcaaattg ggaaacagta ttgccaaaag
    34441 tagaggctgt attcgaataa atttttcatc aactagtatt cggggggaat aaagtatatg
    34501 gaaattttac gtatagagcc aacaccaagt ccaaatacaa tgaaagttgt tttgtcatat
    34561 acaagagaag acaagttatc taatacttat aaaaaagtag aagaaacaca accaagattt
    34621 ataaatcagt tgttatctat agatggtatc acttccattt ttcatgtcat gaacttctta
    34681 gctgttgata aggcaccaaa agctgattgg gaagtcatat tacctgatat taaagctgct
    34741 ttttctgatg cgaataaggt tttagaatct gtaaatgaac ctcaaattga caatcatttt
    34801 ggtgaaatta aagctgaatt attaactttt aagggtatac cgtatcaaat taagctaact
    34861 tctgctgacc aagaattaag agaacaatta ccacaaacat atgttgatca tatgactcaa
    34921 gcgcaaacag cacatgacaa tattgttttt atgcgtaaat ggctagattt aggaaatcgc
    34981 tatggaaata ttgaagaagt aatggatggt gtcctagaag aagtgctagc tacctatcca
    35041 gaatcacagt tacccgtatt ggtaaaacat gctttagaag aaaatcacgc aactaataat
    35101 tatcatttct atcgacatgt ctctttggat gaatatcatg caactgataa ttggaagact
    35161 cgattacgaa tgttaaacca ttttccaaag ccgacttttg aagatatacc gctacttgat
    35221 ttagctttat ctgatgaaaa agtaccggtt agacgtcaag cgattgtatt attaggtatg
    35281 attgaaagta aagaaatttt accgtattta tataaggggc ttcgtgataa aagtcctgct
    35341 gtaagaagaa cagcagggga ttgcataagc gatttagggt atccagaggc actaccagaa
    35401 atggtgctac tattagatga tccacagaaa atcgttaggt ggcgtgctgc tatgtttatc
    35461 tttgatgaag gtaatgcaga gcagcttccc gcactaaaag cccatattaa tgacaatgcg
    35521 tttgaagtta aattacaaat tgaaatggcc atatctcgta ttgaaaacgg agatgaggca
    35581 cttggttcag tatggaaaca aatggcaaac agaacaattt aattggagga attaaatatg
    35641 aatgcatatg atgcttatat gaaagaaatt gcgcaacaaa tgcgtggcga attaactcaa
    35701 aatggtttta caagtttaga aacgagcgaa gcagtatcgg agtatatgaa ccaagtaaat
    35761 gctgatgaca ctacttttgt agttattaac tctacatgcg gctgtgcagc tggattagca
    35821 agaccagctg cagtagcagt tgcaacacaa aatgaacata gacctacaaa tacagttaca
    35881 gtttttgctg ggcaagataa agaagcaact gctacaatgc gagaattcat tcagcaagca
    35941 ccatctagtc cttcgtatgc tttattcaaa ggtcaagatt tagtttattt tatgcctaga
    36001 gaatttatcg aaggtagaga tattaatgac attgcaatgg acttaaagga tgcctttgac
    36061 gaaaattgta aatagtacac ataaataaat ataaaggtta acacatttta taatattaaa
    36121 aatggtgtct gtcattgaaa atagagaata tagttgtatt ctatttgtta aataaagtcc
    36181 gtttttacca actatatttt ctagaaattt aactgtttta ataggacatc aaacataata
    36241 ttcaaatcat gtgttaacct cttttttaaa attttttagc attaaagtta tagatttggg
    36301 taaacaatta ccaattggaa acatatatca cgttacgatg tggtaggtac ttaatcagca
    36361 ttttataaat aaagtaacgg aatt
//
LOCUS       DAPDIM010000027        32861 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000027 DAPDIM010000000
VERSION     DAPDIM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 32861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32861
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.027"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..1118)
                     /locus_tag="RFE25_001337"
     CDS             complement(<1..1118)
                     /locus_tag="RFE25_001337"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDU2816408.1"
                     /translation="MSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFY
                     RFLSEKAEQEYADALSGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIR
                     EIETQDFDIEHLATAIRKVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALIS
                     KVMVNLDDLPFVHSDMEIDMLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVT
                     DGKDKLRHVYDPTCGSGSLLLRVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYEN
                     FDIRNDDTLENPAFLGNTFDAVIANPPYSAKWTADSKFENDERFSGYGKLAPKSKADF
                     AFIQHMVHYLDDEGTMAVVLPHGVLFRGAAEGVIRRYL"
     gene            1196..1297
                     /locus_tag="RFE25_001338"
     CDS             1196..1297
                     /locus_tag="RFE25_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816409.1"
                     /translation="MENFDVGGGIFIFMEIGIGFMTHKQKRLNDDID"
     gene            complement(1382..2065)
                     /locus_tag="RFE25_001339"
     CDS             complement(1382..2065)
                     /locus_tag="RFE25_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL10"
                     /protein_id="HDU2816410.1"
                     /translation="MKFTALAKATLALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEA
                     LYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQVLLPGNDKSKFQQRSYEGLDVFF
                     VQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITL
                     KELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQ
                     IKDIEVNLK"
     gene            complement(2431..3129)
                     /locus_tag="RFE25_001340"
     CDS             complement(2431..3129)
                     /locus_tag="RFE25_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL9"
                     /protein_id="HDU2816411.1"
                     /translation="MKLTALAKATLALGILTTGVFTAESKAVHAKVELDETQRKYYIN
                     MLHQYYSEESFESTNISVKSEDYYGSNVLNFNQRNKTFKVFLLGDDKNKYKEKTHGLD
                     VFAVPELIDIKGGIYSVGGITKKNVRSVFGFVSNPSLQVKKVDAKHGFSINELFFIQK
                     EEVSLKELDFKIRKMLVEKYRLYKGASDKGRIVINMKDEKKYVIDLSEKLSFDRMFDV
                     MDSKQIKNIEVNLN"
     gene            complement(3506..4204)
                     /locus_tag="RFE25_001341"
     CDS             complement(3506..4204)
                     /locus_tag="RFE25_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL8"
                     /protein_id="HDU2816412.1"
                     /translation="MKFTAIAKAIFVLGILTTSVMITENQSVNAKGKYEKMNRLYDTN
                     KLHQYYSGPSYELTNVSGQSQGYYDSNVLLFNQQNQKFQVFLLGKDENKYKEKTHGLD
                     VFAVPELVDLDGRIFSVSGVTKKNVKSIFESLRTPNLLVKKIDDKDGFSIDEFFFIQK
                     EEVSLKELDFKIRKLLIKKYKLYEGSADKGRIVINMKDENKYEIDLSDKLDFERMADV
                     INSEQIKNIEVNLK"
     gene            complement(4543..5238)
                     /locus_tag="RFE25_001342"
     CDS             complement(4543..5238)
                     /locus_tag="RFE25_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL7"
                     /protein_id="HDU2816413.1"
                     /translation="MKLKTLAKATLALGLLTTGVITSEGQAVHAKEKQERVQHLYDIK
                     DLYRYYSSESFEFSNISGKVENYNGSNVVRFNQEKQNHQLFLLGKDKDKYKKGLEGQN
                     VFVVKELIDPNGRLSTVGGVTKKNNKSSETNTHLFVNKVYGGNLDASIDSFLINKEEV
                     SLKELDFKIRKQLVEKYGLYKGTTKYGKITINLKDEKKEVIDLGDKLQFERMGDVLNS
                     KDIQNIAVTINQI"
     gene            complement(5684..6388)
                     /locus_tag="RFE25_001343"
     CDS             complement(5684..6388)
                     /locus_tag="RFE25_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL5"
                     /protein_id="HDU2816414.1"
                     /translation="MKMAAIAKASLALGILATGTITSLHQTVNASEHEAKYENVTKDI
                     FDLRDYYSGASKELKNVTGYRYSKGGKHYLIFDKNRKFTRVQIFGKDIERFKARKNPG
                     LDIFVVKEAENRNGTVFSYGGVTKKNQDAYYDYINAPRFQIKRDEGDGIATYGRVHYI
                     YKEEISLKELDFKLRQYLIQNFDLYKKFPKDSKIKVIMKDGGYYTFELNKKLQTNRMS
                     DVIDGRNIEKIEANIR"
     gene            complement(6752..7630)
                     /locus_tag="RFE25_001344"
     CDS             complement(6752..7630)
                     /locus_tag="RFE25_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL4"
                     /protein_id="HDU2816415.1"
                     /translation="MKITTIAKTSLALGLLTTGVITTTTQEANATTPSSTKVEAPQST
                     PPSTKVEAPQSKPNATTPPSTKVETPQQTPNATTPSSTKVETPQSPTTKQVPTEINPK
                     FKDLRAYYTKPSLEFKNEIGIILKKWTTIRFMNIVPDYFIYKIALVGKDDKKYDEGVH
                     RNVDVFVVLEEKNKYGVERYSVGGITKSNSKKVDHKAGVRITKEDNKGTISHDVSEFK
                     ITKEQISLKELDFKLRKQLIENHNLYGNVGSGKIVINMKNGGKYTFELHKKLQENRMA
                     DVIDGTNIDNIEVNIK"
     gene            complement(7739..7876)
                     /locus_tag="RFE25_001345"
     CDS             complement(7739..7876)
                     /locus_tag="RFE25_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816416.1"
                     /translation="MFVKVAFLCLKSDESSNVPSVESHQNQFYLTNIMDFLIYLTMIQ
                     I"
     gene            complement(7994..9064)
                     /locus_tag="RFE25_001346"
     CDS             complement(7994..9064)
                     /locus_tag="RFE25_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL3"
                     /protein_id="HDU2816417.1"
                     /translation="MNMKTIAKTSLALGLLTTGAITVTTQSVKAEKIQSTKVDKVPTL
                     KAERLAMINITAGANSATTQAANTRQERTPKLEKAPNTNEEKTSASKIEKISQPKQEE
                     QKSLNISATPAPKQEQSQTTTESTTPKTKVTTPPSTNTPQPMQSTKSDTPQSPTIKQA
                     QTDMTPKYEDLRAYYTKPSFEFEKQFGFLLKPWTTVRFMNVIPNRFIYKIALVGKDEK
                     KYKDGPYDNIDVFIVLEDNKYQLKKYSVGGITKTNSKKVDHKAELSVTKKDNQGMISR
                     DASEYMITKEEISLKELDFKLRKQLIEKHNLYGNMGSGTIVIKMKNGGKYTFELHKKL
                     QEHRMADVIEGTNIDKIEVNIK"
     gene            complement(9355..10050)
                     /locus_tag="RFE25_001347"
                     /pseudo
     CDS             complement(9355..10050)
                     /locus_tag="RFE25_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498972.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL2"
     gene            complement(10336..11016)
                     /locus_tag="RFE25_001348"
     CDS             complement(10336..11016)
                     /locus_tag="RFE25_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL1"
                     /protein_id="HDU2816418.1"
                     /translation="MKFKAIAKASLALGMLATGVITSNVQSVQAKTEVKQQSESELKH
                     YYNKPVLERKNVTGYKYTEKGKDYIDVIVDNQYSQISLVGSDKDKFKDGDNSNIDVFI
                     LREGDSRQATNYSIGGVTKTNSQPFIDYIHTPILEIKKGKEEPQSSLYQIYKEDISLK
                     ELDYRLRERAIKQHGLYSNGLKQGQITITMKDGKSHTIDLSQKLEKERMGDSIDGRQI
                     QKILVEMK"
     gene            11488..12333
                     /locus_tag="RFE25_001349"
     CDS             11488..12333
                     /locus_tag="RFE25_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDU2816419.1"
                     /translation="MNIMLTGATGHLGTHITNQAIANHIDHFHIGVRNVEKVPDDWRG
                     KVSVRQLDYFNQESMVEAFKGMDTVVFIPSIIHPSFKRIPEVENLVYAAKQSGVAHII
                     FIGYYADQHNNPFHMSPYFGYASRLLSTSGIDYTYVRMAMYMDPLKPYLPELMNMHKL
                     IYPAGDGRINYITRNDIARGVIAIIKNPDTWGKRYLLSGYSYDMKELAAILSEASGTE
                     IKYEPVSLETFAEMYDEPKGFGALLASMYHAGARGLLDQESNDFKQLVNDQPQTLQSF
                     LQENI"
     gene            12352..12711
                     /locus_tag="RFE25_001350"
     CDS             12352..12711
                     /locus_tag="RFE25_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HDU2816420.1"
                     /translation="MNIISTILIIFVALEFFYIMYLETIATTSKKTSETFNISVDKLK
                     DKNINLLLKNQGVYNGLIGVLLIYGLFISSNPKEICTAILVYIIGVAIYGGLSSNISI
                     FFKQGTLPVLALISMLW"
     gene            13243..13395
                     /locus_tag="RFE25_001351"
     CDS             13243..13395
                     /locus_tag="RFE25_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816421.1"
                     /translation="MVPEEKGSITLSKEAAIIFATAKFKPFKNRIKNNPLKTNPFLKL
                     HENKKS"
     gene            13656..13928
                     /locus_tag="RFE25_001352"
     CDS             13656..13928
                     /locus_tag="RFE25_001352"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDU2816422.1"
                     /translation="MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSI
                     KQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI"
     gene            14327..15031
                     /locus_tag="RFE25_001353"
     CDS             14327..15031
                     /locus_tag="RFE25_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDU2816423.1"
                     /translation="MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYS
                     IAIHSDVTSNKKRYYKSFSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTI
                     VPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALTQKYRDIDIKLSTEDKKL
                     LSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISED
                     DMNEIEKQLKIKFFSN"
     gene            15423..15959
                     /locus_tag="RFE25_001354"
     CDS             15423..15959
                     /locus_tag="RFE25_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816424.1"
                     /translation="MHNKNEFNKKLKDFIGSDKRMALVKGYINEYKLTTVLRALNNSD
                     YTKGTIHTRSIGNLKQIVDNRIIPKNITQNKIFKLSNLTLEVNLYERNTIYHGDFAIY
                     YPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQE
                     DPKQYEILYKNKHGKLPY"
     gene            complement(16072..17613)
                     /gene="guaA"
                     /locus_tag="RFE25_001355"
     CDS             complement(16072..17613)
                     /gene="guaA"
                     /locus_tag="RFE25_001355"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDU2816425.1"
                     /translation="MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIE
                     EIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVER
                     ANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIE
                     DKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGD
                     RRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNI
                     IRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIE
                     SGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFP
                     GPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGD
                     YRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPS
                     TIEWE"
     gene            complement(17638..19104)
                     /gene="guaB"
                     /locus_tag="RFE25_001356"
     CDS             complement(17638..19104)
                     /gene="guaB"
                     /locus_tag="RFE25_001356"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002955225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDU2816426.1"
                     /translation="MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNI
                     PVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFL
                     TPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQE
                     NLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHG
                     RLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLV
                     AGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHG
                     KAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGS
                     LGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSH
                     DLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF"
     gene            complement(19142..20410)
                     /locus_tag="RFE25_001357"
     CDS             complement(19142..20410)
                     /locus_tag="RFE25_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDU2816427.1"
                     /translation="MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDI
                     FMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVII
                     IAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTL
                     IIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGF
                     SFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIF
                     NSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAM
                     IAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQ
                     NGIVLGAISAIILNFFFNGIKYKQTEENVK"
     gene            complement(20410..20988)
                     /gene="xpt"
                     /locus_tag="RFE25_001358"
     CDS             complement(20410..20988)
                     /gene="xpt"
                     /locus_tag="RFE25_001358"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDU2816428.1"
                     /translation="MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYE
                     QFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKN
                     KTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQN
                     GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE"
     regulatory      complement(21219..21321)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            21501..21908
                     /locus_tag="RFE25_001359"
     CDS             21501..21908
                     /locus_tag="RFE25_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDU2816429.1"
                     /translation="MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLH
                     DSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAV
                     RDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA"
     gene            22051..22713
                     /locus_tag="RFE25_001360"
     CDS             22051..22713
                     /locus_tag="RFE25_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816430.1"
                     /translation="MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNK
                     TENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHE
                     LNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHP
                     TNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRK
                     PF"
     gene            22831..23787
                     /locus_tag="RFE25_001361"
     CDS             22831..23787
                     /locus_tag="RFE25_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816431.1"
                     /translation="MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDF
                     KEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVED
                     LRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQ
                     EAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTAT
                     KVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASK
                     QATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL"
     gene            complement(24582..24680)
                     /locus_tag="RFE25_001362"
     CDS             complement(24582..24680)
                     /locus_tag="RFE25_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816432.1"
                     /translation="MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG"
     gene            24765..26153
                     /locus_tag="RFE25_001363"
     CDS             24765..26153
                     /locus_tag="RFE25_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HDU2816433.1"
                     /translation="MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVF
                     GVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKF
                     AKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTA
                     HTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRA
                     IDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYI
                     IHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFA
                     ATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGA
                     TFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDT
                     FESNDNAALTSH"
     gene            complement(26233..26988)
                     /locus_tag="RFE25_001364"
     CDS             complement(26233..26988)
                     /locus_tag="RFE25_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HDU2816434.1"
                     /translation="MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFL
                     QAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYG
                     STEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFG
                     MAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGN
                     RKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR"
     gene            27480..28049
                     /gene="ahpC"
                     /locus_tag="RFE25_001365"
     CDS             27480..28049
                     /gene="ahpC"
                     /locus_tag="RFE25_001365"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002445177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDU2816435.1"
                     /translation="MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPAD
                     FSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDP
                     SQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYV
                     RKNPGEVCPAKWEEGAKTLQPGLDLVGKI"
     gene            28065..29588
                     /gene="ahpF"
                     /locus_tag="RFE25_001366"
     CDS             28065..29588
                     /gene="ahpF"
                     /locus_tag="RFE25_001366"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDU2816436.1"
                     /translation="MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEIS
                     DMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKE
                     KQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREE
                     SENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASG
                     SAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDID
                     AMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAF
                     CPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRS
                     LSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDA
                     VELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN"
     gene            29741..29959
                     /locus_tag="RFE25_001367"
                     /pseudo
     CDS             29741..29959
                     /locus_tag="RFE25_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887771.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30032..30658
                     /locus_tag="RFE25_001368"
     CDS             30032..30658
                     /locus_tag="RFE25_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NDxxF motif lipoprotein"
                     /protein_id="HDU2816437.1"
                     /translation="MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKK
                     LETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTE
                     KQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDI
                     EKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK"
     gene            30928..31311
                     /locus_tag="RFE25_001369"
     CDS             30928..31311
                     /locus_tag="RFE25_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816438.1"
                     /translation="MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNI
                     ILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFIT
                     SIILFISAIITLAIGGKSVDKNDSH"
     gene            complement(31377..31958)
                     /locus_tag="RFE25_001370"
     CDS             complement(31377..31958)
                     /locus_tag="RFE25_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDU2816439.1"
                     /translation="MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLC
                     DYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISAN
                     PKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAH
                     QVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE"
     gene            32136..32345
                     /locus_tag="RFE25_001371"
     CDS             32136..32345
                     /locus_tag="RFE25_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816440.1"
                     /translation="MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLF
                     YPILSTFSNIIIHIDHFHANKKDDN"
     gene            complement(32384..32635)
                     /locus_tag="RFE25_001372"
     CDS             complement(32384..32635)
                     /locus_tag="RFE25_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDU2816441.1"
                     /translation="MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVG
                     GKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK"
BASE COUNT        10643 a         5885 c         4869 g        11464 t
ORIGIN      
        1 attaaataac gacgaatgac gccttctgcg gcaccacgga ataagacacc atgtgggagt
       61 acaactgcca tggtaccttc atcgtctagg taatgtacca tatgttgaat aaaggcaaag
      121 tctgctttgg attttggcgc aagcttgccg taaccactga agcgttcatc attttcaaat
      181 tttgaatctg cagtccattt cgcactgtat ggtgggttcg ctataaccgc atcaaatgta
      241 ttgcctaaga aagctggatt ttccaacgta tcatcattac ggatatcaaa gttttcatag
      301 cgcacatcat gtaataacat gttcatgcgc gctaagttgt aagtggtatt gttacgttct
      361 tgaccgaaat aacgatacac ttgcgtttct ttaccaacac gtaacaataa tgaacctgaa
      421 ccacatgttg ggtcatacac gtgacgtaat ttatctttac cgtctgtgac aatcttcgcc
      481 agtatcttag atacttgttg tggtgtatag aactcgcctg cttttttacc tgctgtcgcc
      541 gcaaagcgcc cgataagaaa ttcgtatgca tcacctaaca tatcaatttc catatcactg
      601 tgaacgaatg gtaagtcgtc aaggttaacc ataactttgg aaattagtgc agtacgttct
      661 ttgacattgt tacctagtcg cgttgaactt aagtccatat cgctgaacag tccgataaag
      721 tcattttcac tttcttcacc tagtgttgat gtttcaactt tacgaatcgc cgttgcgaga
      781 tgttcgatat cgaaatcttg cgtttcaatt tcacgaatca tcgcactgaa taaatcttgt
      841 ggttcaatga agtaaccgac ttgatcaatt aattcagctt ttaagtcttc acgatattct
      901 tcatctgccc atgcttcttg atacgtaata tcttcacctg acaaggcatc tgcatattct
      961 tgttccgctt tttcagataa gaagcgatag aaaatcaagc ctaaaatgta attacggaat
     1021 tcactcgcat ccatattccc tcttaaatca ttcgcaatcg accataattt tttatgtaat
     1081 tcagcttgtt gctgacgttg tttttcagta atagacatgt gattcctccg cctttgaata
     1141 agtaatttat ctctttgtgt aatagattta ttataacatt tggttatgtt gcgatgtgga
     1201 gaattttgat gttggtggtg gaatttttat attcatggag attgggatag gattcatgac
     1261 acacaaacaa aaacggctta acgacgatat cgattgatgc atcctttttg tataagctat
     1321 gcgcaccaat ttacatttca ccgttaagcc gcttcaatta ctttttatta ttcgtaatta
     1381 tttactttaa gttaacttca atatctttaa tttgtttgct ttctatgact tcccccatat
     1441 atttaaattt taatttagat cttaaatcaa ggttataaaa actgccatct ttcaagctaa
     1501 ttttgaccct accatctttt gagattgttt tataaagtcc gtatttttca attagatgct
     1561 ttctcaactt ataatccagc tcttttagtg ttattttttc ttttttaatg taataagggt
     1621 aacctttcac aaaagcatct tcaccctttt cttttgaaat atttaatatt ggtgcactga
     1681 caactccaga tgttttatta ttctgtatta caccaccaac agtataaaat atatcgtgct
     1741 tatctctttt ttcttgaaca aaaaacacat ctaacccctc ataactacgc tgttgaaatt
     1801 tacttttatc atttccaggc agtaaaactt gaatcttaat acctctaaac ttaaaacgca
     1861 agttattttt accatgtttc aaagcactaa tatttttcat ttccatagtc tttccagtgt
     1921 agtatcggta tagtgcctcc ttgtcatgtt tatttactga cttttgattt tgttttgcat
     1981 gacctgaatg aacttctgtt gttaaagttc ctgttgttaa aattcctaaa gctaatgttg
     2041 cttttgctaa tgctgtaaat ttcatattta tttgctccaa tcttaatata ttggattgtt
     2101 ttcattacgt aatttgaatc atacattttt attataacgt gcatcgtttc atacgataat
     2161 taacctcgat ttaaatatac ttgaattatt cttaatgaaa aacaaatata ttttaatgtt
     2221 caggttaaat gactttcatt atttcattta gttgttttac tggattatcg tttactacaa
     2281 ctgatgatgt tactctgttc tgctctttga attacaaaaa caacttaaca acagtaatgt
     2341 atttaacaca gttccttata taaggacaca gatgtcaatt cacattttgt cgttaagtcg
     2401 cttcttaagc tattatgcta ttaactcaaa ctaattcaaa ttcacttcaa tatttttaat
     2461 ttgcttacta tccattacat caaacatacg atcaaaactt aatttttcac ttaaatcaat
     2521 tacatatttc ttttcgtctt tcatattaat aacgattcta cctttatctg acgcgccttt
     2581 atacaatcta tatttttcga ctaacatttt tcttatttta aaatccagtt ccttcaacga
     2641 tacttcttcc ttttgaataa agaacaactc atttatcgaa aagccatgtt tagcatcaac
     2701 ttttttaact tgtagacttg gattacttac aaatccaaac actgatctca catttttctt
     2761 tgttataccg ccaacgctat atatgccacc ttttatatct attaattcag gtactgcaaa
     2821 gacatcaagg ccatgtgttt tttctttata tttattttta tcgtcaccaa gcagaaacac
     2881 tttgaaagtt ttatttcgtt ggttaaagtt taaaacgtta gaaccatagt aatcttcact
     2941 tttaacgcta atgtttgttg attcaaaact ttcttcagaa tagtattgat gtagcatatt
     3001 gatataatat ttgcgttgtg tctcatcaag ttctactttc gcgtgaacag ctttactttc
     3061 tgctgtaaac acacctgtag ttaatattcc taatgctaat gttgcttttg ctaatgcagt
     3121 caatttcata tttatttgct ccaatcttga tatattggat tgttatgatt acgtaatttg
     3181 aactatctgt ctttattata aggtgcatca aaacagactg acattaacgc tcatttaaat
     3241 aaacttgaat cattattaat gaaaatcaaa cgtattttaa cattcgtatt aactgatttt
     3301 taatagcaac ataaattttt ttgggggaat cattgttctt tccgattagt tttagatctt
     3361 aagttattcg atacaaagtg tacaaaaaag cagcttaata acgtagtcaa tgttcgatat
     3421 gtttttatta ttaaaacacg tatcaaaatc attaaacatg ggattattaa accgcttctt
     3481 aagcttttat tctatatatc attgattatt tcaaattcac ttcgatgttc ttaatttgtt
     3541 cactattaat gacatctgcc atacgctcga aatctaattt atcacttaaa tcaatttcat
     3601 acttattttc atctttcata ttaataacaa ttctaccttt atcagctgac ccttcataca
     3661 gtttgtattt tttaatcaac agttttctta ttttaaaatc aagttccttc aatgacactt
     3721 cttccttttg aataaagaaa aattcatcaa tagaaaaacc gtctttatcg tctatttttt
     3781 taactagtaa gttcggcgtt cttagagact caaatattga ttttacgttt ttcttcgtta
     3841 caccactaac actaaatatt cttccatcta aatctactaa ttctggtacc gcaaagacat
     3901 ctaaaccatg tgttttttct ttgtatttat tttcatcttt tcccaataaa aatacttgga
     3961 acttttgatt ttgttggtta aaaagcaaaa cgttagagtc ataataacct tgactttggc
     4021 cactaacatt tgttaactca taactaggtc ctgaatagta ttgatgtaac ttgtttgtat
     4081 catataaacg gttcattttt tcatactttc cttttgcatt aaccgattga ttttctgtta
     4141 tcattacact tgttgttaat attcctaata caaatatcgc tttagctatc gctgtaaatt
     4201 tcatattcat atgctccaat cttaatatat tggattgctt ttattacgta atttgaataa
     4261 tacacattta ttataaaggg cattgagaca gactgacatt aacactcgtt taattaaaat
     4321 taaatcatgg ttaatgaaga actaattaat attcaatgga catcactttc agaagtaatg
     4381 tgaattttta gtacgctcat accctgcgtt ataaaacata aaaacagcct aacgacactg
     4441 ttgatttaga tacgcccctt tttggaggat gtacgtattt attcaacatt tcatcgttaa
     4501 gctgcttcaa atttattact ttaaagtcat tgattgttta atttaaattt gattaatagt
     4561 cactgctata ttttgaatat ccttactatt caacacatca cccatgcgct cgaattgcag
     4621 tttatcacct aaatcaatta cttccttttt ctcgtctttc aaattgatag tgatcttacc
     4681 gtatttagtc gtacctttat ataaaccata tttttcaact aattgctttc taattttgaa
     4741 atcaagttct ttcagtgaaa cttcttcttt attaattaaa aatgagtcaa ttgatgcatc
     4801 taaatttccg ccatacactt tattaacaaa taaatgtgta ttagtttcag aagatttgtt
     4861 atttttctta gtcacaccac caacagtaga tagtctaccg tttggatcaa ttaattcttt
     4921 taccacaaag acattctggc cttcaaggcc ttttttatat ttatctttat cttttcctaa
     4981 taagaataat tggtgatttt gtttttcttg gttaaagcgt acaacgttag aaccgttata
     5041 gttttcaacc ttaccactaa tattactgaa ttcaaaactt tctgatgagt agtatcgata
     5101 taagtcttta atatcatata aatgttgtac tctctcttgc ttttcttttg cgtggactgc
     5161 ttggccttct gatgtaatca caccagtagt taataagcct aatgccaatg ttgctttagc
     5221 taacgttttt aatttcatag tactattctc ccaatctatt tataaatttt gtcttaatat
     5281 atttttatat gattaattca attacgtaat acgaacaatc tactatcatt atataagcga
     5341 gatactgcgc tatgaattaa cctcttttta actatttttg aaccaacgtt aagttagtta
     5401 atgaaatcct aacagtatta attatttttt ataacacaat gctaattttt taactattca
     5461 cactttccct caatttaatt atgttttcca cattgtttca tgtcactaaa gcgacatcac
     5521 gcatctataa gtatcaacta tttccacaag ttttattggt gtttttatta ttcatcgata
     5581 cgcttcattt tcatctcgcc aacacaaaaa agaagctaag caacttatgt tgcctaactc
     5641 ctctatacta tccatatttt actattatcc atatttcatt gaattatcta atgttggctt
     5701 ctattttttc aatatttcta ccgtcaatga catcactcat gcgatttgtt tgtaattttt
     5761 tattaagttc aaacgtataa tagccgccat ctttcattat cacttttatc ttactatctt
     5821 taggaaactt tttatacaga tcaaaatttt gaattaaata ctgtctcaat ttaaagtcga
     5881 gttctttaag tgaaatctct tctttataaa tgtagtgtac tctaccgtac gtagcaatac
     5941 cgtcaccttc atctctcttg atttgaaatc ttggtgcgtt tatataatca taataagcgt
     6001 cttgattttt cttagtgaca ccaccatatg aaaacactgt gccgttgcga ttttctgctt
     6061 ctttaacaac aaatatgtct aatcccggat ttttgcgtgc tttaaatctt tcaatatctt
     6121 taccaaatat ctgtactctt gtgaattttc tatttttatc aaagataagg taatgcttgc
     6181 cacctttgct ataacgataa ccagtaacat ttttaagttc cttacttgcg ccactatagt
     6241 aatctcttaa gtcaaagata tcttttgtca cattttcata ttttgcttca tgttcactcg
     6301 catttacagt ttgatgcaat gacgttattg ttcctgttgc taaaatacct aatgctaaac
     6361 ttgctttcgc aattgctgcc attttcatag ttgtatgctc cattcgtaat tattagattt
     6421 gttcgcttac gtctattgaa tcatacagct ttattataat tggcgtattt gacctttcac
     6481 attaaaccat ctttaataat cattgaatca ttattaagta aattaaggaa tctataatgt
     6541 tcgttaaata aaactgattc cgttgtgctt cacacccgat agatagggat ttacagataa
     6601 attcaggact cttccacgtc atatttggac ccatcgaaaa ttcgggttct caaatcatcg
     6661 aacataacaa aagaagctaa gcaacatgta ggccgttgtc actgaacttc ttgtttttcc
     6721 gatgacagct tctatttaga gaatgtcatg attattttat attcacttca atgttatcaa
     6781 tattagtgcc atctatgacg tctgccatgc gattttcttg taattttttg tgtaattcaa
     6841 acgtgtactt tccaccgttt ttcatgttaa taacaatttt acctgaacca acgttaccgt
     6901 acagattatg attttcaata agttgttttc tcaatttaaa atcaagttct ttcaaggaaa
     6961 tctgctcttt agtaatcttg aattctgaaa catcatgaga gattgtacct ttattatctt
     7021 ctttagtaat tcttactcct gctttgtgat caactttttt actattactc tttgtgatac
     7081 caccgaccga gtatctttcc actccatatt tatttttttc ttctaaaacg acaaatacat
     7141 cgacattcct atgtactcct tcatcatatt ttttatcgtc ttttccaact aaagctattt
     7201 tatatatgaa ataatctgga acaatattca taaatcttat tgtcgtccat ttttttaaaa
     7261 taataccaat ctcattttta aattctaaac ttggtttcgt ataatacgct cttaaatctt
     7321 taaatttagg atttatttct gttggtactt gttttgtggt tggcgattgt ggtgtttcca
     7381 ctttagttga agatggtgtt gtcgcgttcg gtgtttgttg cggtgtttcc actttagttg
     7441 aaggcggtgt tgtcgcgttt ggttttgatt gcggtgcttc tactttagtt gagggcggtg
     7501 ttgattgtgg tgcttccact ttagtggaag atggtgttgt cgcgtttgct tcttgcgttg
     7561 tcgttgtgat tacacccgtt gttaaaaggc ctagtgctaa acttgtttta gcaattgttg
     7621 ttattttcat agttgtatgc tccattcgta attattagat ttgttcgatt acattcattg
     7681 aatcatacag ctttattata gatggcgtat tgctccattc acattaaacc ttgtttaact
     7741 atatttgaat catcgttaag taaattaaga aatccataat gttcgttaaa taaaactgat
     7801 tttgatgtga ttcaacactt ggcacatttg aggattcgtc acttttaaga catagaaatg
     7861 ccacttttac aaacaaatga atattcgtct tttacatcat tacgcataat aaaagaagct
     7921 aagcaacatg taaaccgttg tcacttaact tcttgtttta ccgatgtcag cttctattta
     7981 gagaacgtca tgattatttt atattcactt caattttatc aatgtttgta ccttctatga
     8041 catctgccat acgatgctct tgcagttttt tgtgtaattc aaacgtatac ttcccaccgt
     8101 ttttcatttt aataacgatt gttcctgaac ccatgttacc gtaaagatta tgtttttcaa
     8161 taagttgttt tctcaattta aaatcaagct ctttcaagga aatctcttcc ttagtaatca
     8221 tgtattctga agcatcgcgt gaaatcatac cttgattatc ttttttagta acgcttaatt
     8281 ctgctttgtg atcaactttt ttactattag tcttcgtgat gccaccgaca gaatattttt
     8341 ttaattgata tttattgtct tctaaaacga taaatacatc gatattatcg taaggtccat
     8401 ctttatattt tttctcatct tttccaacta aagctatttt atagatgaac ctatttggaa
     8461 taacattcat aaacctaacc gtcgtccatg gtttgagcaa aaatccaaac tgcttttcaa
     8521 attcaaaact cggtttcgtg taatacgctc ttaaatcttc atatttagga gtcatatctg
     8581 tttgtgcttg ttttatggtt ggagattgtg gtgtgtctga tttagtagat tgcattggtt
     8641 gtggcgtgtt tgttgatgga ggtgttgtca ctttagtttt cggcgttgtg gattcggttg
     8701 tcgtttgtga ttgttcttgt ttaggcgctg gcgttgctga tatattaagc gatttctgct
     8761 cttcttgttt aggttgtgat attttttcta ttttggaagc tgaggttttt tcctcattag
     8821 tatttggtgc cttttcgagt ttaggcgtgc gttcttgtct tgtgttagct gcttgtgttg
     8881 tcgctgaatt tgcacctgct gttatgttta tcattgctaa tcgctctgct ttaagcgttg
     8941 gtactttgtc aactttagtt gattgtattt tttctgcttt gaccgattgc gtcgttactg
     9001 taattgcgcc tgttgttaaa agccctagtg ctaaactggt tttagcaatt gttttcatat
     9061 tcataattgt atactccaat ctatattata ttcgattgtc tttttacgta atttgaatca
     9121 tacaacatca ttatagatgg cgttctaaga taatcacatt aaaccctttt taacaattat
     9181 tgaagtatta ttaagtaatt taagcaaaaa ataatgagtg attatgaggt taatatagcg
     9241 tttctatgtg cctttgaaat gatttttaag cattaaaaag aagttaagca acgtttgatc
     9301 gtcacttaac ctctctattt caatttcaaa ttatttcgtc gtcaagtatg tgtattaagc
     9361 ttttctaact ttgatttcaa ttctatcaat atctgtgaca ttgataacat cggacatacg
     9421 gtcttcttgt aactttttat ccaattcaaa tgtatacttt ccatagtatt tctttttgac
     9481 ggtaattttc cctgtactca tttcaccgta aagaccataa ttatcaataa ggtattttct
     9541 taatttaaaa tcaatctctt tcaatgacat cgcttcttta tctattttaa atgggaaaaa
     9601 gtcataatca tattcaccaa tatgatccgc tttaataact cttgcttctg ctattaggtc
     9661 gacagcttta tcgtttgcac tagtgatacc cccaatagag tactttgcac cttcaaatct
     9721 cttatcctca ttaacgtaaa atatattaag attacgatgt acacccgtat gataatgttg
     9781 cttatctttg ccaattaaag caaggttatt aacagaatta ccatctatga tattcataaa
     9841 tttaatactt ggttaaatga aactgatata acctgtcaca tttttatatt caatactagg
     9901 ttgagtataa taagctttta attttttgct attttcactt attacaatag gtttcttttc
     9961 ggcatgaact ggtttttccg ttgtagtgtt tacacctgtt gctaatattc ctaataacaa
    10021 acttattttt gcaatatttt tcattttcat agttgtatgc tccaatctat tataattaga
    10081 ttgttttatt acgtaatttg aaccatacac ccatattata ggagctgtat tcggatattc
    10141 acattaacct gtttttaact attcataaaa tatgattaag ctatttaagc aaaagataat
    10201 gcgtggtgcg actgtttgtg tgagttttgt aacttttccc ctcaaaaaaa gaagctaagc
    10261 aacagtacgt cgcttaactt ccatatattt ccataacaag cactattcaa catagcgctt
    10321 tgttgttaga aagtattatt tcatttctac tagaattttt tgtatttgtc tgccgtcgat
    10381 agaatcaccc atacgttctt tttcaagttt ttgacttaaa tcgatagtat gtgatttgcc
    10441 atctttcatt gtaattgtaa tttgaccttg tttaagacca tttgaataca agccgtgttg
    10501 tttgattgca cgttctctta atctataatc aagttctttc aatgagatgt cttctttata
    10561 aatttggtat aaactacttt gtggttcttc tttacctttc ttgatttcaa ggattggtgt
    10621 gtgtatatag tcaataaaag gttgactgtt tgtttttgtt acgccaccaa ttgagtaatt
    10681 tgttgcttgt ctactgtcac cttctctaag gataaacaca tctatattcg agttgtctcc
    10741 atctttaaat ttgtctttat cagatccaac taaagaaatt tgagaatatt gattgtctac
    10801 tataacatct atataatctt tacctttttc agtatattta tatccagtaa catttttacg
    10861 ctctaaaacc ggtttattat aatagtgttt caactctgat tcactttgtt gtttaacttc
    10921 tgttttcgct tgtactgatt gtacattcga tgtaattaca cctgttgcta acattcccaa
    10981 tgctaaactt gcttttgcta tcgctttaaa tttcataatt tttagcccca atctatttaa
    11041 atttgatttt tcaattacgt aatatgaaca atctacctac attatattga ggcgctatcc
    11101 cctttcaaat taaacctcat ttaactaaac ttgaatcatt gttaaggtaa ttaataaaat
    11161 gctaactgtt attaatcaat tcttatccgt cgagactctt ttttatacaa atcacacttt
    11221 ataccatttt tattttaaaa actgtaaaac tttcagacac aaaacagaca tcatattgtc
    11281 gtagtacctg attaaaattt tcaaagatat tagtgataca catcaactaa aacgcgtcat
    11341 tacggtattt tcaacattaa taacatatac gtatttacta tacacagcga taataaatac
    11401 agattacaat tttttataaa atcaaatgtt ttgaaaacaa tcgaataagt attatgttat
    11461 gtatataaag attaggagat gaagtgaatg aatattatgt taacaggtgc tacaggtcat
    11521 ttaggcacac atattacaaa tcaagccatt gcaaatcaca tagatcattt tcacattggt
    11581 gttagaaatg ttgagaaagt tccagatgat tggcgtggaa aagtttctgt tcgacaatta
    11641 gattatttta atcaagaaag catggtagaa gcatttaaag gaatggatac cgttgtgttt
    11701 attccaagta ttatccatcc atcattcaaa cgtattcctg aagtggaaaa tttagtatat
    11761 gcggcaaagc agagcggcgt tgctcatatc attttcatag gttattacgc agatcagcat
    11821 aataatccat tccatatgag cccttatttc ggatatgcat cacgtttatt gtcaacaagt
    11881 ggcattgatt atacgtatgt aagaatggca atgtacatgg atccacttaa accctattta
    11941 ccagaattga tgaatatgca taaactgatt tatccagctg gtgatggtcg tattaattat
    12001 attactagaa atgatattgc tagaggtgtc attgctatta ttaaaaatcc agatacttgg
    12061 ggcaaacgct atttattatc aggctatagt tatgatatga aagaacttgc tgctatttta
    12121 tctgaggcat caggcacaga aattaaatat gaacccgttt cattagagac atttgcagaa
    12181 atgtacgatg aacctaaagg ctttggtgca ttattggcat caatgtacca cgcaggagca
    12241 agaggactat tagaccaaga atccaatgat ttcaaacaat tagtcaatga tcaaccacag
    12301 acactgcaat catttttaca agaaaatatt taataataaa ggagcgttac agtgaatatc
    12361 atctcaacaa ttttaatcat atttgtggca ttagagtttt tctatattat gtaccttgaa
    12421 acgattgcta caacttccaa aaagactagc gagacattta atataagcgt cgataaattg
    12481 aaagacaaaa atattaacct acttttgaag aaccaaggcg tatataacgg tttaatcgga
    12541 gttttgctaa tatacggttt gtttatcagc agtaatccaa aagaaatatg cacagctatt
    12601 ttagtgtata tcattggcgt tgctatttat ggtggccttt caagcaatat tagtatcttt
    12661 ttcaaacaag gcacattgcc agtattggca ctcatatcaa tgctttggta agtattggtg
    12721 tttgggggtt tggagatgta gtctggggtt gagagtttgg agggtttgag tgttttgggt
    12781 gtggacgttc ataaactcag agtatttcat cctaattatt tcaagcagag gtgacagtag
    12841 cgtttcctct gtttccttat agaaaaatga tttaatgaag aaaacccata tctgttttaa
    12901 tttttagctg ataaatactc catatattag aatggctact ttatctattg catcaatcct
    12961 ttaaaacaaa aaacccatga tttcgaaatt cccgtatggt ggggttccta ctctcatgga
    13021 tctattaaat aaattatcac tataagttta ttatttcaat attattaaca atatatgtag
    13081 tcgtaaaagg aaagaggaca tgagaacttc ggtgttgatt ggcattacat aacgcttcca
    13141 aacatattat ttggtaacaa taagaaacta tttacacaac ctattttgta tagtaaaatt
    13201 attttataag atttaaatcc aattgtacaa ggagtgaata tcatggtacc agaagaaaaa
    13261 ggttctatta ctttgtcaaa agaagctgct atcatatttg caaccgcaaa attcaaacca
    13321 tttaagaaca gaattaaaaa taacccacta aaaacaaatc catttcttaa attacatgaa
    13381 aacaaaaaat cttaataact ttatttatag catttctaat ctcagaaatg ctataaagga
    13441 caacgccctc tttcataact atataagtca agaaaccaag acatttcaaa catctttaaa
    13501 cccttcaata gcacattccc taaaacataa agcaataaca atgaacgatc aaaattcctt
    13561 acgtacttat gatgtgtcag tgaatcgtct acacttaatt gaacaaattc tatgagaata
    13621 gatattgtta aattaagaaa gtagtcaatc ttattatgac aaaagaaaga agaacattta
    13681 gttcagagtt taagttacaa atggttagat tatataaaaa tggtaagctt aagaatgaaa
    13741 ttatacgaaa gtatgattta aaaccctcaa ttatctcaaa ttcgataaaa caacaccaaa
    13801 atactggacc cttcaatcat caagataatt taaaaagtga tgaaaaagag ttaataaaat
    13861 tacgcaaaga agttcaacat ttaaaaatgg aacatgatgt tttaaagcaa attttaaagt
    13921 tgatttagaa actgaacttt ttaaagatac attacttgaa gattctaatt tatctgatta
    13981 tataaagaac caacttccaa cgatatggag agactaagaa atagtttaaa tttatttaat
    14041 ttcaataaaa actcataata atatttaagt aagttagatt gcttttagca ttaggaattc
    14101 gcttataatt agatgttcaa tatagacttt tttacacata catgaactat aaaaagcgaa
    14161 taaatagaag gtcattgcga aatttgctaa atacaaaatt gatgagttcc acctaataaa
    14221 aattgttggt tttatagtaa catctatttt cgtaccattc atgttaattt cagtgctaat
    14281 aatgctgata taaagaagaa taaattgatt aggagaacac tatttaatgt ctaaaaatat
    14341 caatcaagca aatagtaaat taaatacgtc aaacaaaaaa ctaaaacaag cttattcaaa
    14401 atccgatagt aaaaacatga aagttatata catgcctcat tggctagagt tttattcaat
    14461 tgctatacat agcgatgtta caagcaataa aaaaagatat tataaatcat ttagtagagg
    14521 aacagtggta tatgtaaaac tagggagtaa tattggaagt gagttttctg gtaatcattt
    14581 ttgtgtaata ttagataaca aagacaataa aggaaaagaa acagttacaa tagttccact
    14641 ttcttccaaa ggtaataaaa attatttgaa gttaaacgaa tcggtgctaa atctaacagc
    14701 aacagattta aaaaaacaga ttatcgatat cagtagtaaa gtacaagcat taacccaaaa
    14761 atatagagat attgacatta aacttagcac agaagataaa aagcttttgt ctaacttaaa
    14821 tcaaaaagct aatgaactgt atagagtgat aggtgtttat tccaagcaca aagggaaaga
    14881 tacatacgtt aatatatcag caattacaac aataagcaaa agacgtataa gcaaaataaa
    14941 tgattctgat cctactggaa cgataataat ttcagaagat gacatgaatg aaatcgaaaa
    15001 gcaattaaag ataaagttct tttctaattg aattgtaata ttacatctga tataattgat
    15061 ttacaaattc ccggtaacca ttccggcttc attctcttga agaatgacat attctcagcg
    15121 ttttagctga aggtcagatg atacgtcatc tggcctcttt ttttatataa atgcccttta
    15181 agtgaaatat acaacaatct gcaaccaata tagacatcac aaaacacaca ataaattaca
    15241 caatgtgtta taagccacat gtcattatta tcgtagctag ctgcgtcact caaaacgaat
    15301 acggaacgcg ttggttattc caatcataat attactctgc aaatacacag ccctgtatcc
    15361 gagtaaatga atagagattt gaacaaatga aaacaatcaa ctaatggaaa ggataaaata
    15421 ttatgcacaa caaaaatgaa ttcaacaaaa aactgaaaga ttttataggt agcgataaac
    15481 ggatggcttt agtaaagggt tatattaacg agtataaatt aacaactgtt ttaagagctt
    15541 taaataattc cgattacaca aaagggacga tacacactcg ttcaataggc aacctaaaac
    15601 aaatagtaga taatcgaatt attcctaaaa atataactca aaacaaaatc ttcaaattga
    15661 gtaatttaac cttagaggtt aacctctatg aaagaaacac aatttatcac ggagactttg
    15721 ctatttacta tcctgtagaa tctgctctaa taatagaaac agatactcct aggctaatta
    15781 atcatataaa taacaaccca gtccaaaaaa tatttataat aacaacaaat gactggagct
    15841 ttaatacact tgaattagaa aaaatagtag acgaaactat aatttatgat ttaaaacaag
    15901 aagatcctaa acaatatgaa attttatata aaaataaaca cggaaaattg ccttattgat
    15961 gaattaaaac gcaaacttag aacaccttac cccttttccg tccttattgt aattttccaa
    16021 ctactcaaat taaaaaccac ccgtgcaaac aggtggtttt attatatata attattccca
    16081 ctcaattgtg cttggtggtt ttgatgtaat gtcatagact acgcgattga cgtggtctac
    16141 ttcgtttacg atacgacttg aaatcttttg taagacttcc caatcgatgc gtgcgaagtc
    16201 acttgtcatg ccgtcgatag atgttactgc acggatacct actgtgtgat catacgtacg
    16261 gtagtctccc ataacaccta ctgattgaat gtttggtaac actgtgaagt attgccaaat
    16321 ttctctttca agaccttctt ctctaatcac ttggcgtaaa atcgcgtctg attctctaac
    16381 gatttctagt ttatcttcag taatttctcc aagtacacga ataccaagac caggtcctgg
    16441 gaatggttgt ctccacacta aatgttctgg aatacctaat tcaataccta atttacgtac
    16501 ttcatcttta aacaatgtat tgattggttc gattaattcg aattccatgt cttctggtaa
    16561 tccaccaaca ttgtggtgtg atttgattgt ttgagctgtc ttagtacctg attcgatgac
    16621 gtctgtatat agtgttcctt gcgcaaggaa gtctacacct ttaagttttg atgcttcatc
    16681 atcaaataca tatacaaatt cattaccaat gattttacgt ttttgttcag gatctgaaac
    16741 accttttaat ttattcataa aacgatcttt cgcattaaca cgaataatat tcatgttgaa
    16801 cccttcaccg aattgttcca taaccatgtc gccttcacct ttacgaagta agccatggtc
    16861 tacaaagata catgttagtt gatccccaat tgctttatgc aataatacag caacaacaga
    16921 tgaatctacg ccaccactca tcgcacataa tacacgacgg tcgcctacgc gttgacgaat
    16981 cttttcaatt tcaatttcga taaagttttc catcgtccat tgtcctttac aatcacaaac
    17041 acgacgtacg aagttgttta ataaatcatt accatattct gtatgacgta cttctggatg
    17101 gaattgcaca ccataaatgc gacgtttctt atcttcaatt gctgcatagt ctgtgcttgg
    17161 gctatcagcg ataacttcaa agccttctgg aatttcaata actttatcag aatgactcat
    17221 ccaaacagtt tgttctgctg gtaagccagc gaataactca tctgacttcg cattaatgat
    17281 tgctttaccg tattcacgtt cattggcacg ttcaacttta ccacctaata atttagtagt
    17341 taattgcatg ccgtaacaaa taccaagtac tggaattcct aaattatata tttccggatc
    17401 aattgtaaat gaaccttctt cataaactga atttggacca cctgataaga tgataccttt
    17461 tggattcatt ttcttaattt cttcaattga aatttcatga tcgtgtaatt cactataaac
    17521 gcccatttca cgaattcggc gtgtaattaa ttggttgtat tggctaccaa agtctaagac
    17581 aaggattaac tcttgttctt ttgccatttc catatttgtc gttctccttt atcttaatta
    17641 gaatgagtag ttcggtgatt ctttcgtaat ttgaatatta tgtggatggc tttctgctaa
    17701 accagcagga cccatacgtg taaattgtgc ttcttcgcgt aattctctta aatcgtgtga
    17761 accagtataa cccataccag cacgcacacc gcccattaat tggtaaattg tatcttgtaa
    17821 cgcaccttta taagccgtac gtccttcgat accttcagga acaaatttct taggcgcttt
    17881 gtcctcttgg aagtaacggt cgtttgaacc tttttccatc gcacctaaag agcccatacc
    17941 acggtatact ttatattgtc taccttggaa aatttctgta gcacctggac tttcttcagt
    18001 acctgctaat aagctaccta acataaccgc atgtccacca gcagctaatg ctttaatgat
    18061 atctcctgag aatttaatac caccatcagc aatgatagct ttaccatgtt tgcgtgcttc
    18121 agttgcacaa tcataaattg ctgtaatttg tggtacacca acacctgcta caacacgcgt
    18181 cgtacaaatt gaacctgggc caataccaac tttaacaata tctgcacccg cttcaaataa
    18241 atcttttgtt gcttctgcag ttgctacgtt accagctact aatgtgattt ctgggtaagt
    18301 cttcttaata tgtttcactt gatcgataac gcctttagag tgaccatgtg ctgtatcgat
    18361 aactaagaca tccacacctg cttcgactaa tttttgagca cgaatatcag tatcttttga
    18421 aataccaatt gctgcggcta caagtagacg accatgttca tcttttgctg cattagggaa
    18481 ttcgataact ttttcaatat ctttaatagt aataagacct tctagacgtc cgtctttaac
    18541 taatggtaac ttttcaatct tatgtttttg gagaattttt tctgcttctt caagtgttgt
    18601 attcactgga gctgtaatta aattttcttg cgtcattaca tctacaattt taattgagaa
    18661 gtcttcaata aaacgtaagt cgcggtttgt taaaatacct actaagttgc gatcttcttt
    18721 attatcaaca attggtacac ctgaaatacg gtatttaccc attaatgctt ccgcttcata
    18781 aacactttct tctggtgtta agaaaaatgg gtttgaaatg acaccatttt ctgagcgttt
    18841 tactttttga acttcgtccg cttgttcttc aacgcccata tttttatgaa taacacctaa
    18901 accaccttga cgagccatag caatcgccat tttagattca gttactgtat ccataccagc
    18961 agaaataact ggaatattta atttaacttt gtctgataat tgtacgctta aatcaacgtc
    19021 tttcggtaaa atatcagatt gtgctggaat taataacaca tcatcaaacg ttaatgattc
    19081 ttttgcaaat ttactttccc acattaaaaa cagcctccat ttttcaaatt aattagttat
    19141 attatttcac attttcttcc gtttgtttat actttattcc attaaaaaag aaattaagaa
    19201 taattgcaga gattgcgcct aaaacaattc cgttttgagt caaccatgca aattgttcac
    19261 ctaaaccttt aaatgcttgt ggtacagcgc ttataccagt acctaatcct actgatacag
    19321 caataattaa taaattgttt tgatttttaa aatcgatatg tcctaatata ctaacaccat
    19381 atgccattac catgccaaac atagctatca tcgcaccacc taacacaggt agcggtatga
    19441 tatttgctaa tgcaccaagc ttaggtatac aaccacatat aagtaataac acgaccatgc
    19501 cgtatataac attatttttc ttagcgccgg ataaagaaac aagtcctaca ttttgcgaat
    19561 aggctgtata cggaaatgaa ttgaatatag aacctaacac tatcgctaga ccttccgcag
    19621 tataaccttt acgaaaatct tttctttcta acttcttacc ggtaatttca cttaacgcat
    19681 gatagacacc tgtcgactca attaaactaa cgatagctac aataaagaac actaacgtcg
    19741 atgtcacatc aaagctaaat cctgagaatc taaacggcac tgggatgcct aaccaaccgg
    19801 catgattgac ttgattaata tcgaccatcc caagtaagcc agcacctatc gttcctaaaa
    19861 cgagtccaat taatatggca atactcttaa taaatccagt tgtgaatctt tgtaaaacaa
    19921 gaataatgat taatgtcatt aaacctaaca aaatgttctt aacatctcca tagtcctttg
    19981 caccttgacc tccagctaag taattcattg ctactggcat taaattgata ccaatgatag
    20041 taacaacact acccgttact actggtggga agaattttac aagatgtgaa aagaaaggcg
    20101 cgatgataat aactaatatc cctgataaaa atagcgaacc gtaaagtaca tctattcctt
    20161 tcgtttgacc aattaaaatc atgggcgcaa cagccgtgaa tgtacatcca agaacgattg
    20221 gtaatcctgt tcctgttact ttattggctt gtaaaaatgt ggcaacccca cacataaata
    20281 tatctactgt aactaagtaa gcgatttgtt caggtgtaaa cttcaaactt gtaccaacaa
    20341 tgattggaac taagatggca cctgcgtaca tagctaaaag atgttgaaca cttaggatta
    20401 aatttttcat tattcttctc ccaccaatgt cactttgttt ccttctagtg aagcaacctt
    20461 gcagagagaa gaaactgtta aacctgcttc ttctaaacgt tgatgcccat tttggaaact
    20521 cttttcaaca acaataccaa taccagctgt cttagcattc gcttgctgtg cgatatcgta
    20581 taatcctaat gaagcatcac catttgctaa aaagtcatcg atgatgagta cagtatcttc
    20641 ttctgataaa aattcttttg aaacaatgac cgtacttgtt ttatttttag taaatgaatg
    20701 aatagatgtt tcataataac catccgtcaa agtgctaggt tttgcttttt tcgcaaataa
    20761 acatggcaca tcaaaatgca gtgcagccat gattgcaggt gcgataccgg aagcttcaat
    20821 ggttaagatt ttagtaatcc ctttatcttt aaattgctcg taaaaagtgc gaccaacttc
    20881 attcattaac tttgcatcaa tttgatgatt taaaaatcca tcgactttta aaatcttctc
    20941 atcaatgaca acgccgtctt cctttacttt ttgtcctagt aactccactc ttaaaacctc
    21001 ctcagatttg tgtgaaacat tttgctctta aattggtgct agatacaaaa aaatccccaa
    21061 actaaataat agtttcaggg tttatgagtg aacgaacatg cataacgaat ttgtcatgca
    21121 atcaatgtaa aagaagtttc atcaaataaa ctgtgaccat catataaaat gatataaatc
    21181 acccaccatg gttacaattt aatggctgaa gctactccta gtattgtgtt gttactcata
    21241 gtcatgtcgt tcaaggcaac atggtagaaa cttctaaagc catattcttt agattatatg
    21301 agtttatgta aattatttaa cgataatagc aaattttcgg cattttttca ataactgctt
    21361 aggtaatctt ttaatagttt tataaatgta cagagacgtt taatgcgaat gaagacttat
    21421 aacttaataa tgtaagggtt ttactttata ataagaaggg taaaagatta aataaacaaa
    21481 tttttaaagg ggcgacaact atggcagata ttactgtagt aaatgacact ggcgaattat
    21541 acaacgtaat caatcaaaag aaatctgaag gttatttaga atcagagcta acaattatta
    21601 gtaaaagtaa attacaccta aatgacttac acgactctga aatctccctt atctcaacaa
    21661 gtggaacatt tagtgataga atgactaaac tgttaacagg agaagatggt gaacatgcag
    21721 ttttatcacg ctacaactta gcgcctgatg aattagaaaa atataaacaa cttattttag
    21781 acgataaaat gttagttgta gcggttcgtg acaaatcatc acataaagaa gttcaagaac
    21841 ataactcagc atatgaagaa attgatatta ctcattttgc tgaagcatct aaaggtccca
    21901 aagcttagtt atcacactga attcaaaatg agattactgt actgtctaat ttaagatagt
    21961 acagtttttt ataccattta aaagtttatg aacaatcttt tacagcaggc gattatgcta
    22021 taatattatt taaattgggg aggtgttctt atggaattta aaaccattca atctgtcaaa
    22081 gatccacatt acaacgaagc acttaaactt tacgatacta agttaaattt atctttaact
    22141 gaagataaac gtatcatcaa acgctcatta gaaaacaaca aaaccgaaaa cgattatgtc
    22201 tttatcgtag gcttagaaaa cgatgttgtt gtcagtctag caactgcaca ttatgaagcc
    22261 acaaccaatt cagcattttt aatttattta ttcgcaaaag acctacccaa ccatgatgag
    22321 ttaatgacac aaacattaca tcaaattgaa catgaactaa acttattatc aaaccttgtt
    22381 cattctagaa gtattaactt tttaatgatg gaagtcccta aagaacctgc agatttaaca
    22441 caagataacg gacttattat tgaacaccgt agacagtttt tatacgaaca tcaatttgaa
    22501 agacaaactg aaattgatta cattcatcca actaatgatg gtcacactaa aaaagtggac
    22561 ttatttttaa agaaaaatat taaactgaca aaggatatct acggtacaag tgttaaatca
    22621 aattatattt tgaagtatgt atttgccaat ggtatcgcac gtgaaattat ttatgcttta
    22681 ttagaagaaa tggatttacg taaaccattt taaacaaact tgaaatcact aacaataacg
    22741 tttaaactat gtatgaagca agactgacgt ttcactgccc gtagacaaac gtcagtatac
    22801 ataaagtata tgcagaaagg actttaaagt atgttaacta aagaatttgc acaacgcgta
    22861 gaactaagtg agaagcaagt ccgtaaaatt gttcaacatt tagaagaacg tggttaccaa
    22921 ctaagcaaga ctgaatatcg tggtcgtgaa gcaactgatt tcaaagaaga agatatcgag
    22981 cttttcaaag acattgccga caaagtaaaa caaacaaata gttatgatct agcgtttgat
    23041 gaattagaaa aagaaaaaga cttcctgcaa gtcattgtca aaaacgatga caaaaactta
    23101 cctactaatc aaaatgtcgc tcaactagta gaagatttac gcctagaaat ccagaaaatg
    23161 cgcgaagaac gtcacctact tggtcaaatg atgaatcaag tacatcagca acaacaagaa
    23221 ttaaaagaac ttcaaaatca acttacatct aaaatcgatt caaatagcga atccttaaaa
    23281 gccatccaaa catcacaaga ggctatccaa gaagcacaag catctcaagc taaagtattg
    23341 gctgaatcaa caaataaagt tgaaaagaat gctgttactg aagataaagc tgacagtaaa
    23401 gattcgaagg ttgctggagt gaatacatca acagacgcta agacggatac taaagcagaa
    23461 aatgcaggcg atggcactgc tactaaagta gataaagagg atcaaatttc tgcaactgaa
    23521 gcaattgaaa aagccagcgt tgagcagtct aaaaatgaaa atgcagctga gacttcaaat
    23581 aaagaagcta cagtagatgc agacgcgcaa catgatgctg aacaacaagt agcagaagcc
    23641 catgcagaag cttctaaaca agctacttcg aacgattcat tggaagcgaa agcagaaaat
    23701 gacagcacag cttcacagtc agaaatgtca gaaccaaaac ctcaagaaga gaaaaaaggt
    23761 ttcttcgcac gtttattcaa cctgtaaact tgtgatttga acacaaattt aatactcaat
    23821 tcatatatag ctttgattta aaaactgatt ttttataaac ctatagaact gtaatttact
    23881 ttcaaattta atactcaatt cataaaacct gaaacaagct gatatactcc attcaatatc
    23941 tactttgaag agagcatatc aaactaattt gtttcaggtt ttttaattat tcattatgat
    24001 taatattgaa ttttgaataa atttttatag tatgttactt ttaaatggga tggctcctgt
    24061 gtattcctaa atagattcat cttaataagc ccattcaatt taaatgtttg gctgtgttag
    24121 taaatgacga atcacacaag ggcacactca tattcacatt tactacaaac gccttttttc
    24181 tcaaacaaaa atatttgttt acggtagctt ttgaactacc acctgcacac acgaaccctc
    24241 aaaagatgct aattttgatt cgacagaatt ttttacaacg tgtttgttcg aagcgtcttt
    24301 tcaaggttga tcatttatta tctttttatt caataaatat gaggttagca atttttatca
    24361 aaccgtcata gccacatctc gattcaagga tgcatttgtt ttctcatatc ttatctctta
    24421 tgacagtgca cgatatatat cttttccaaa tattcatcac ttttttcctg ttaaaatcat
    24481 ttctattatt aacgctgtaa tgacaactta tttaatttat tgcatttaat gccctgcttc
    24541 attttcaaat atcaacttta atcgactagg tcataacact attaaccctt ttcacctttc
    24601 tctactaaat tcaaaacgat ttgtttacaa attcccttat gccaacggtc gaatttcatc
    24661 atgtttacat ttaattgcaa atgccctctt gaaatatttt aaaattaata ttattcttag
    24721 catactagtc ggaattatat tcaaaaattt gaggagtgac gttcatgaat gcttttctta
    24781 cactgattaa tattattgta ttggtgattt tcatcgtaat attgcacatg atggctcgca
    24841 aacatatatc ttttgcgaaa cgtgtgttta cagctttagg tatcggcatt gtatttggcg
    24901 tgttattaca tcttgtctat ggaacacatt cgaatgttat tacatcaaca agtgactggt
    24961 tcaacattgt cggacaaggt tacgttgcat tgttgcaaat gattgtgatg cctttaattt
    25021 tcatttctat tgtcgctgca ttcactaaaa ttcaaatcgg agaaaagttt gctaaaattg
    25081 gtagtctcat ttttatcttt ttaattggca ctgtcaccat tgctgcaatt gttggtgttg
    25141 tgtatgcctt ggtgtttggt ttagatgcat caacaattaa tcttggtaac gctgaacaag
    25201 cacgtggaag cgaaattgct aaacaagcga aagatttaac agcacatacg ttaccacaac
    25261 aaattttgga attattgcct aaaaatccat tcttagattt cactggacaa cgtgcaactt
    25321 ccacgattgc tgtcgtgata tttgcttcgt ttataggatt tgcttattta cgcgtagcac
    25381 gcaaacaacc tgatcatggt gaattgctta agcgtgcgat tgacgctatc tattcactag
    25441 taatggcgat tgtgacgttc gtcttacgtt taacgccata cggtgtatta gcaattatgg
    25501 ccaacacatt atcgacaagt gactttggcg ccatttggac tttaggaaaa ttcttaatcg
    25561 catcgtacgc tgcattaatt acgatgtata tcattcactt aattatttta agcctgttag
    25621 gtattagccc aattcgctat gttaaaaaga ctttggaagt attaatcttt gcattcacat
    25681 cacgctcaag cgcgggtgcc ttaccattga atgtacaaac acaaacaaga cgtctaggcg
    25741 tgccagaagg tattgccaat ttcgctgcga catttggatt gtcgattgga caaaatggtt
    25801 gtgcaggcat ttaccctgcc atgcttgcaa ttatggtcgc acccgtcgct aatgtagaaa
    25861 ttgatttaca atttattgta acgttaatcg ctgtcgtgat tattagttca ttcggcgttg
    25921 ctggcgtcgg tggcggggct acatttgcat ccatattggt gttgtcaacg ttaaacttgc
    25981 cagtcgcttt agccggcgtg ctcatctccg ttgaaccatt gattgacatg ggtagaacag
    26041 cattaaacgt gaacgattca atgctagctg gtacaggtac cgccaagtta acaaaacatt
    26101 gggacaaaga tactttcgaa tcaaatgata atgctgcatt aacttcacac taattcattg
    26161 caagaaatac ccgccccctc tagctatact tatcatttta agctagaggg ggcgggttat
    26221 tttggtatct tgctatcgct gtattaagcc tgatttttgc aattgttcta acatatctaa
    26281 tcttgctttg tttcctagga acatctcaat ttgctgcgac catgtttctt tgcgattccc
    26341 gtttgtacgt tgatcatagt actcgctgat tgtctggtcg taatctgcca tttgtgcata
    26401 ctgtgtttcc ttatcagcat gatacttatt atgatggaag acatggtcaa atggtaagcg
    26461 tggcttggct gcaccatttt catcatctgc gggttcccct actgccatac caaataccgg
    26521 gaagacatag tcaggtaagt ctaaaatttc tcgaactcgt tcaacatcat ttcttaatga
    26581 tcctaaaaag acaatgccat accccatatc ttcagcagtt accgcaatat tttcagcaac
    26641 taatgctgca tcgattgcac ctactagcaa accttccgtt gaaccatatg cattttccat
    26701 atcagtttca gcatgttgat caactaaatg atgacgataa taatcaataa caaagacgaa
    26761 taaatagcca ttttctacaa cataaggttg tccagaaact tctcgtaaat tttctttaat
    26821 cttctcatcg tcgataccaa taattgagta tgcttgtagg aaacttgacg tcgaagcgct
    26881 ttgtccagct tctaccaatt tcttaacaac gtcttcactt aaaggtttat tcttaaattt
    26941 tctaacagaa tgatgctttt tcacaagatt atatacataa tctgacacgt tacccactcc
    27001 tcgatacttt acagttaatt aaaaatcttc atattgcaat tgtacacgtc caaacttttt
    27061 tatagcaatt atttgcttat aagttaataa ttgaactttt aaaaatattg tctcgtactt
    27121 gaaaattcca gtttctcact aatcaccttc atccatctcg aacaaatatt ctcacaccat
    27181 tatcaataag gttgacttag ttgagaatac aaatcttctt tttttacatt ttttacatta
    27241 aaatcaagat attaaatata gacacaacct tttaaatcat caactacaaa atccattatc
    27301 aaagcacttt atattatctt tctttatttt aaaagtaatc gttcacttta caaagttatc
    27361 cagttgacta ttctggatca aaatgtaata atgctaacta agagattaga attattataa
    27421 ttaagcacaa tcaattgata gttctaattc atacttaaat tcttaggagg aagatattta
    27481 tgtcattaat taacaaagaa atcttaccat ttacagcgca agctttcgat ccaaaaaaag
    27541 atcaatttaa agaagttaca caagaagatt taaaaggttc ttggagcgta gtatgcttct
    27601 atcctgctga cttctcattc gtttgtccaa ctgaattaga agacttacaa aaccaatatg
    27661 aagaattaca aaaattaggc gtaaatgtat tctcagtatc aactgatact cacttcgtac
    27721 acaaagcatg gcatgaccat tcagatgcaa ttagcaaaat cacttacact atgattggtg
    27781 acccatcaca aacaatcact cgtaattttg atgtattaga tgaagctact ggtttagctc
    27841 aacgtggtac attcattatc gacccagacg gtgttgtaca agcatctgaa attaacgctg
    27901 acggaattgg ccgtgacgct agtacattag ctcacaaaat caaagcagct caatatgttc
    27961 gtaaaaaccc tggcgaagta tgcccagcta aatgggaaga aggcgctaaa acattgcaac
    28021 ctggtttaga tttagtaggt aaaatctaag gaggcattac aaccatgctt aatgctgatt
    28081 taaaacaaca acttaaacaa ttattagaac taatggaggg caacgttgaa ttcgttgcca
    28141 gccttggttc agatgaaaaa tctaaggaac tcaaagaatt attaacagaa atttctgata
    28201 tgtcacctag actttcactt tctgaaaagt ctttaaaacg tacaccaagt ttctcagtca
    28261 accgtcctgg cgaagaaaca ggtgtaacat ttgcaggaat tccattaggt cacgagttta
    28321 actcacttgt tttagcaatt ttacaggtta gtggtcgtgc acctaaagaa aaacagtcaa
    28381 ttattgacca aattaaaaac ttagaaggtt cattccattt tgaaacattc attagtttaa
    28441 cgtgtcaaaa atgtcctgat gtcgttcaag cacttaactt aatgagtgtg atcaacccta
    28501 acatcacgca ttctatgatt gatggtgcag tgttccgtga agaatctgaa aacatcatgg
    28561 cagtccctgc tgtcttttta aacggcgaag aatttggcaa tggtcgtatg acaatccaag
    28621 atattctttc gaaactaggc agtacggcag atgcatctga gtttgaaaat aaagaacctt
    28681 atgatgtctt aatcgttggt ggtggtcctg ctagtggtag tgcagcgatt tacacagcac
    28741 gtaaaggttt acgtactggt atagttgctg atcgtatcgg tggccaagtt aatgatactg
    28801 ctggtattga gaacttcatt actgttaaag aaacaactgg ttctgaattt tcttctaact
    28861 tagcagcgca cattgatcaa tatgacattg atgcaatgac aggtatacgt gctacagata
    28921 tcgaaaagac tgacgaagca attaaagtta cgttagaaaa cggtgctgtc ttagaaagta
    28981 aaacagtcat tattgctact ggtgcaggtt ggcgtaagct aaacattcca ggtgaagagc
    29041 aattgattaa taaaggtgtt gcattctgcc ctcactgtga cggacctcta ttcgaaaata
    29101 aagacgtagc agttatcggt ggcggtaact ctggggttga agcagcaatt gaccttgctg
    29161 gtatcgttaa tcatgttaca ttattcgaat tcgctagcga attaaaagca gacaacgtgt
    29221 tacaagatcg tttacgttct ttatcaaatg ttgatatcaa aacaaatgcc aaaactactg
    29281 aagttgtcgg agaagaccat gttacaggta tacgttacga agacatgagc accggcgaag
    29341 aacatctact taacttagat ggtatctttg ttcaaattgg tttacttcca aacacatcat
    29401 ggttaaaaga tgctgttgaa ttaaacgaac gtggtgaaat tgttattgat cgtaacaata
    29461 atactaacgt acctggaata tttgctgctg gcgatgtcac agatcagaag aacaaacaaa
    29521 ttatcatttc aatgggcgct ggtgcaaatg cagcattaaa tgcctttgac tatattatca
    29581 gaaactaaag ttttcacagt ttcactgaca gtatcttaca tttgttaaga tgctgttatt
    29641 tttttatccc gacataaaat catgttatga taaacttaat atatacaacg agatgtgcga
    29701 taatgcttaa agtatgtacc tctcgcaaac aaatcaatat gaaaatgata ttgagaagga
    29761 aaagtatgtg aacgaaatca ttatgctttt acgtacgata cctacatcta aattgataca
    29821 accaattatg cagttattta tagataatgc tatccttaac attgttcaaa acgacgcatt
    29881 attgatagaa aaagcaactc atgcacgtaa tcatttgcgt ctatggtcat tgcaaggtca
    29941 tcgtgacatt ccaaactaat tcaatgttac tctattaaac atgaatacat attttttcaa
    30001 ttaaagataa actaaggagt tatattacat tatgaaaaag agattactac taagtacatt
    30061 tttagcatct gcattaattc ttacaggttg cgcgtccgat caatctgata acgaagatca
    30121 tcacacaagt actggcatcc atgcacctaa aagcgctaaa aaattagaaa caaaagatat
    30181 ctttaactca gataagaaaa atagtgatat tagtgatgca gagatgaagc aagctataga
    30241 aaagtatttg tctgtaaata gcgatatact tgataacaaa tatattatgc aacataaact
    30301 agataaacaa attgacagtc aaacaaaagt gactgaaaaa caagcagaaa cacttagcca
    30361 cttatctaac ttagctgtta aaaacgattt gcatttcaag aaatttgtca ctgaaaacaa
    30421 tattcctaaa gaatataaga aacccgttga attaatgatg aattacttca aagctttaaa
    30481 tagtacaatc gccaatgttg atgaagatat tgaaaagctt agctatcaac cgcaaaataa
    30541 aatcaatgta gtcgacgtgc caacaaaata tgccggtgat gttaataaaa agcaacaaga
    30601 taaaattaaa gatttcttaa aatctaaagg tatcaagagt gatgttatcg ataaataact
    30661 gaaagccatc attgcgacat gtaacacatc attacatgag ctttaattca tgacaattct
    30721 ttatctttaa aagtgactaa tctttgagac aatacaattt aaccaatacc ttaccatttt
    30781 gcatcaagca gcatattact gtttgatgct tttttaattg ccttaaattc tctatctatg
    30841 ccaaaatcac ccattagttg acgcatttga ctatatccct aacatatttc atacttatat
    30901 tgactctata aacaaaggat ggtcatgatg aaagttcgaa ttacttttat tattttagca
    30961 attttatcga cgattgtttg cttgttctta gcagcaatgc atccaacagg accaaacaca
    31021 gtaacttttg aacagccata tttattcacc ctcaacatca ttttaatggt attagtcgca
    31081 ttaccttcac ttgttttagc tatatatgat tatatgagtt ttagaatttc ttctgctatt
    31141 ttacaatttc taggggctat ctcttggttc tttttatcat tgatattatc gctcacacaa
    31201 tttacacctt ttacattagc gtcatttata acttcaatta ttttgttcat aagcgcaatt
    31261 atcacattag ctattggtgg taagtctgtt gataagaatg attcccatta aattccaaat
    31321 gccaaaaagg ttctgaaggc cactataaaa cacagctttt cagaacctct atacttctat
    31381 tcaatgatat atggtttgca attttctacc tttaaatcca cagcttcttc ccttgaaact
    31441 ttgttaaaat aaaccatcaa acaacgaatg acaacttgat gtgcaacaat gacaatatca
    31501 tctttttgtg tatcttcatt gacaacatga ttcataaaat gttctacgcg ttgatataca
    31561 tcttcataac tttctccttc aggcgctttt tgtgaaaaac tatgacgaaa gtctttaaag
    31621 tttggatcat tgaaatattt ttcatatttc ggattcgcac tgatttcatc tttatattca
    31681 ccctcaaata cgccaagtga acgttctctt aatagagggg tagtcgttga tgcaatgtca
    31741 tatggaaaaa tatgttcaaa cgtttgctgt gttcttaata agtctgaaac atatacatgt
    31801 ttaatctgtt tctctttaaa ataatcacat aaatcgtctg cactttttgt gccagtatcc
    31861 gttaacggca catctaattg tccacaaaaa taagatcgaa aatgtttatt atcataattc
    31921 gattttgatt cgccatgtct aactaaataa atcgtcataa tattactcct taccttatgt
    31981 atttcatatc taccataaca ctttgactac taattcgata tcaatcttaa tattctattc
    32041 taaaaaaaga attaattcat attttaaatt aatgactcta aaaatagtat tgtctttaat
    32101 caagtgatgt gttactatat gggtgtagtt cttaaatgac tacacagtct tttatattca
    32161 tgaacataat actcctggat ggcgcaaccc aacgtcatcc tttttttatt tgtcaaatac
    32221 tcgctttttt atttccaaaa tttcctcata ttaatttatt acttttttat cctatcttat
    32281 ctacattttc aaatattata atacatattg accattttca cgcaaataaa aaagatgaca
    32341 actgaatgcc atctttattt caatttccaa ttgaattttt ttattattta cgcatagctc
    32401 ttaaaattaa cgttacgatt gcaattaaga taattgaacc aattaatgct ggcaagatgt
    32461 aaatacttcc taattcagga ccccattgtc cgaatagttt gccacctacc catgatccaa
    32521 taatacctgc gataatattg cctaaaatac cacctgggat atctttaccc ataatagcac
    32581 cagcagccca tccaattaag ccaccgacaa ttaacattcc aataaatcca aacataattt
    32641 tcagtctcct ttttctattt attttgcgtt attctaagta gtacccctta tttacaattc
    32701 taaaacaaat tcaaattatt tttatccaaa tatttttaaa agtagtaatt gaatatcaat
    32761 tttattcaat gtagctatcg ttatttaaag tctctgtact ggcaatatca tatacattta
    32821 cattattttt tctgccgaat tcatagcttg attattttat g
//
LOCUS       DAPDIM010000028        32622 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000028 DAPDIM010000000
VERSION     DAPDIM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 32622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32622
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.028"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            18..644
                     /gene="recU"
                     /locus_tag="RFE25_001373"
     CDS             18..644
                     /gene="recU"
                     /locus_tag="RFE25_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HDU2816442.1"
                     /translation="MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSN
                     TFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEAYFRTPSTTDYNGVYQGYYIDFE
                     AKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWK
                     RYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV"
     gene            641..2824
                     /locus_tag="RFE25_001374"
     CDS             641..2824
                     /locus_tag="RFE25_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDU2816443.1"
                     /translation="MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFF
                     VVLLLGILLFAYYAWKAPAFTEAKLQDPIPAKIYDKNGELVKTLDNGQRHEHVNLKDV
                     PKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLS
                     QHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKD
                     LNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDL
                     KANLVNRTPEERQNIDTNQDSEYNSYVNFVKSELMNNKAFKDENLGNVLQSGIKIYTN
                     MDKDVQKTLQNDVDNGSFYKNKDQQVGATILDSKTGGLVAISGGRDFKDVVNRNQATD
                     PHPTGSSLKPFLAYGPAIENMKWATNHAIQDESSYQVDGSTFRNYDTKSHGTVSIYDA
                     LRQSFNIPALKAWQSVKQNAGNDAPKKFAAKLGLNYEGDIGPSEVLGGSASEFSPTQL
                     ASAFAAIANGGTYNNAHSIQKVVTRDGETIEYDHTSHKAMSDYTAYMLAEMLKGTFKP
                     YGSAYGHGVSGVNMGAKTGTGTYGAETYSQYNLPDNAAKDVWINGFTPQYTMSVWMGF
                     SKVKQYGENSFVGHSQQEYPQFLYENVMSKISSRDGEDFKRPSSVSGSIPSINVSGSQ
                     DNNTTNRSTHGGSDTSANSSGTAQSNNNTRSQQSRNSGGLTGIFN"
     gene            complement(3390..3731)
                     /locus_tag="RFE25_001375"
     CDS             complement(3390..3731)
                     /locus_tag="RFE25_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816444.1"
                     /translation="MTNITKEVFDNLEQEIDVFAKNKALGSSEAKPYLDEYHSKIIDY
                     FKQVNDITSNIDFDNLNQYPVVPMNFKERYDYMIERKYHFMGYRQMKTFKTELIKMNA
                     SYQTRLKNKQV"
     gene            complement(3736..4395)
                     /gene="nth"
                     /locus_tag="RFE25_001376"
     CDS             complement(3736..4395)
                     /gene="nth"
                     /locus_tag="RFE25_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDU2816445.1"
                     /translation="MVSKKKALEMIDVIANMFPDAECELKHDNPFELTIAVLLSAQCT
                     DVLVNRVTTELFKKYKTPEDYLAVSDEELMNDIRSIGLYRNKAKNIKKLCQSLIDQFN
                     GEIPQTHKELESLAGVGRKTANVVMSVAFDEPSLAVDTHVERVSKRLGINRWKDNVRQ
                     VEDRLCSVIPRDRWNRSHHQLIFFGRYHCLARKPKCDICPLLEDCREGQKRYKASLKE
                     A"
     gene            complement(4385..5071)
                     /locus_tag="RFE25_001377"
     CDS             complement(4385..5071)
                     /locus_tag="RFE25_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HDU2816446.1"
                     /translation="MDKYQLKARPVVIRRELLDHYSDLGLDEQDLVILLKLIYASETS
                     NKQPSIELLQKGSTMQPRDITMVIQNLIQRELLELQVQKDEEGRFTEYMNLDPFFEKL
                     SHILKQQSMETKEQNSKEKFKQLFRVLEDTFARPLSPYEIETLNQWIDVDKHDSAIIQ
                     AALDEANSLNKLSFKYMDRILLNWKKNNVKTIDDSRKIREKFNKPKMTHTVKTVPKFD
                     WLNGENLDGK"
     gene            complement(5399..6691)
                     /gene="asnS"
                     /locus_tag="RFE25_001378"
     CDS             complement(5399..6691)
                     /gene="asnS"
                     /locus_tag="RFE25_001378"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDU2816447.1"
                     /translation="MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQ
                     GVVVKSEVDEEVFKLAKEIAQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYP
                     ITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
                     APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIE
                     FWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKILERDTSKLEKVATPFPR
                     ISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNP
                     ENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGS
                     VPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP"
     gene            complement(7013..9706)
                     /locus_tag="RFE25_001379"
     CDS             complement(7013..9706)
                     /locus_tag="RFE25_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase DinG"
                     /protein_id="HDU2816448.1"
                     /translation="MGMATYAVVDLETTGNQLDFDDIIQIGITFVRNNQIIDTYHSMI
                     RTNLEIPPFIQALTSIEENMLQQAPYFNQVAQEIYDKIKDCIFVAHNVDFDLNFIKKA
                     FKDCNIQYRPKKVIDTLEIFKIAFPTDKSYQLSELAEAHGITLANAHRADEDAATTAK
                     LMILAFEKFEKLPLDTLKQLYYLSKQLKYDLYDIFFEMVRQYDAKPLDKSYEKFEQII
                     YRKQVDFKKPTTNYNGSLKSLYSKAVDQLGLTYRPQQLYLAETILDQLMHSEKAMIEA
                     SLGSGKSLAYLLAALMYNIETGKHVMISTNTKLLQSQLLEKDIPAMNEALNFKINALL
                     IKSKSDYISLGLISQILKDDTSNYEVNILKMQLLIWITETPSGDIQELNLKGGQKMYF
                     DQKIETYVPARHDVHYYNFIKRNAQNIQIGITNHAHLIHSDVENSIYQLFDDCIVDEA
                     HRLPDYALNQVTNELSYADIKYQLGLIGKNENEKLLKAIDQLEKQRILEKLDIAPIDI
                     FGLKASMNEIHELNEQLFSTIFTIINDSDVYDDDIHRFHNVFTFETKDILKDLHAIID
                     KLNKTLEIFNGISHKTVKSLRKQLLYLKDKFKNIEQSLKAGHTSFISIKNLSQKSTIR
                     LYVKDYAVKDVLTKQVLEKFKSLIFISGTLKFNHSFEAFKQLFNKDVHFNTFEVNTSL
                     QSAKNTSVFIPSDVASYQYKNIDEYVASIVSYIIEYTTITSSKCLVLFTSYKMMHMVQ
                     DMLNELPEFEDYVVLTQQQNQNYKIVQQFNNFDKAILLGTSTFFEGFDFQANGIKCVM
                     IAKLPFMNKHNAKYWLMDSEFTSTFKEYVLPDAVTRFRQGLGRLIRNENDRGIIVSFD
                     DRLINSNYKNFFEQTLENYRQKKGDIQQFGKLLRQIQKKKK"
     gene            complement(9730..10701)
                     /locus_tag="RFE25_001380"
     CDS             complement(9730..10701)
                     /locus_tag="RFE25_001380"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDU2816449.1"
                     /translation="MSKYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLK
                     LEGCKIDSVNHKGHLLQQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKSL
                     VGNQSSFFILSDEQTKGRGRFNRHWSSSKGQGLWMSVVLRPNVAFSMISKFNLFIALG
                     IRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANNDGIEAIICGIGINLTQQLE
                     NFDESIRHRATSIQLHDKNKLDRYQFLERLLQEIEKRYNQFLTLPFSEIREEYIAASN
                     IWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEAGESHRLISADIDF"
     gene            complement(10688..11890)
                     /locus_tag="RFE25_001381"
     CDS             complement(10688..11890)
                     /locus_tag="RFE25_001381"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499992.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDU2816450.1"
                     /translation="MDKSLFEQARPILEQIQDNGFEAYYVGGSVRDYVMGRNIHDIDI
                     TTSATPDEIESIFSHTIPVGKEHGTINVVFNDENYEVTTFRAEEDYVDHRRPSGVTFV
                     RDLYEDLQRRDFTMNAIAMDTAYKLYDYFDGQQDINNRIIRTVGIAEERFQEDALRMI
                     RCLRFQSQLSFDIAMETFEAMRTQMADIKFLSIERIVIELTKLMRGINVEESFNHLKS
                     LKAFNYMPYFEQLDMNQINVTEPIDLELLIAIVSVKFDINYSLKPLKLSNRQVKDINQ
                     YIQIMNALPSIITKEQLKMFVYDYDTNLIKNVMVAADVLKANDIQGHEPLIVNLQTID
                     ETLHRLPMHNRKDMMVNGGVLMAHLNAKSGPWLKDVLRQIEIAIVTGKVSNEETEILK
                     WVDNHVKI"
     gene            complement(11895..13037)
                     /gene="bshA"
                     /locus_tag="RFE25_001382"
     CDS             complement(11895..13037)
                     /gene="bshA"
                     /locus_tag="RFE25_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-alpha-D-glucosaminyl L-malate synthase
                     BshA"
                     /protein_id="HDU2816451.1"
                     /translation="MKIGITCYPSMGGSGIIATELGIKLAERGHEVHFITSNIPFRIR
                     KPLPNMIFHQVEVNQYAVFQYPPYDITLSTKIAEVIKEYDLDLLHMHYAVPHAICGIL
                     AREMSGKDIKIMTTLHGTDITVLGYDHSLQGAIKFGIEKSDIVTSVSKSLAQETHEII
                     ETNKEIIPIYNFVRENEFPTKHNTALKSQFGIAPDEKVLIHVSNFRQVKRIDTIIETF
                     AKVREKIPSKLILLGDGPELVPMRQLTKELNVEEDVLFLGKQDCVSEFYQLSDLVLLL
                     SEKESFGLTLLEAMKTGVVPIGSNAGGIKEVIKHGETGFVVDVGDCDSASDYAIRLLE
                     DKALYNKLQKNMLADIAERFGSELITDQYEYYYQKMLNEHNKSKGE"
     gene            complement(13281..13598)
                     /locus_tag="RFE25_001383"
     CDS             complement(13281..13598)
                     /locus_tag="RFE25_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDU2816452.1"
                     /translation="MKSMVEMQREVDEYIGQFKTGYFSPLANLARLTEEVGELAREIN
                     HTYGEKKKKDSEEANTIKAELGDNLFVLLCLANSMGIDMTESFNETMEKFNTRDKNRF
                     ERK"
     gene            complement(13934..14614)
                     /locus_tag="RFE25_001384"
     CDS             complement(13934..14614)
                     /locus_tag="RFE25_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002456509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDU2816453.1"
                     /translation="MIIYFVILMVLPLWAQHKVKSNYEKYSQVRSTSGKTGREVALEI
                     LHANGIYDVEVVKGEGFLTDHYDPKKKVVSLSPANYDRPSVAGTAIAAHEVGHAIQDH
                     QGYWFLRFRAALVPVANLGSSLSYMIIMLGIILTAIGSAFGSTALWIGAGLMSLAVLF
                     SIVTLPVEFDASSRAMKQITALNIVNEKEYKHARKVLSAAAMTYVAATAVAVAELVRI
                     ILIARSSD"
     gene            complement(14686..15273)
                     /locus_tag="RFE25_001385"
     CDS             complement(14686..15273)
                     /locus_tag="RFE25_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1405 domain-containing protein"
                     /protein_id="HDU2816454.1"
                     /translation="MTINTFWQYTLYQRSWLMMLLICNILGMIYGYIWYGEQLSHTPW
                     HFKIFVPDSPTAILYLVISISLILIQKQNSIIEALAFVTLFKYGIWAVIMNILFIIEQ
                     GDITVNGLVLMFSHSIMAVQAIYFYPRFKRSMIGISVAMIWVFLNDYIDYFHLQFPYY
                     DFITTHVWQIGVLSCCLSVFGLLLYIELNKLLKCK"
     gene            complement(15263..15838)
                     /locus_tag="RFE25_001386"
     CDS             complement(15263..15838)
                     /locus_tag="RFE25_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HDU2816455.1"
                     /translation="MSETLNQIKESFIEYLLFQYRFKSRIAVWVLNYIKVNEAKLANI
                     HFVDTKINHHETLEIAEVGSHASAIQFTKRNIKLMNTNEIFDYIANHNCAFDIQIHFA
                     NVSKREQRLDDLIVAQLTESPSYQTYLHDLNSMAIDRHKHALLIDYLLHNIDLSLQMN
                     EKQRFYQLTQILNTLKLVNKHNQFEDLADDD"
     gene            complement(15852..17096)
                     /locus_tag="RFE25_001387"
     CDS             complement(15852..17096)
                     /locus_tag="RFE25_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816456.1"
                     /translation="MEDIYKLIDDINLQKLENLDSRVNEAITTDNDDALFILGETLYN
                     FGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSYVEPSPEKLMLE
                     ADLYQQINMMEVAIDKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETG
                     EYQVNGVNLFSRMADCSLQSGNYSDAIRLYDEINEDEMTSEDYLKKAISYDKNDITQE
                     AIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGC
                     LEIEHGDANEGVLLLKQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLD
                     PTFMWHLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMSDYYFYLIEIGQKEQAITIL
                     NQLLELEPSNENWHDELSRLQS"
     gene            complement(17103..18401)
                     /gene="aroA"
                     /locus_tag="RFE25_001388"
     CDS             complement(17103..18401)
                     /gene="aroA"
                     /locus_tag="RFE25_001388"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDU2816457.1"
                     /translation="MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYK
                     PLLGEDCRRTMDIFRLLGVDIKEDEDKLVVNSPGYKAFKTPHQVLYTGNSGTTTRLLA
                     GLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGIN
                     YQMEVASAQVKSAILFASLFSNDTTVIKELDVSRNHTETMFRHFNIPIEAERLSITTT
                     PDAIQHIKPADFHVPGDISSAAFFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMG
                     GNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELPVIALLCTQAVGTST
                     IKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIG
                     MMLAVASLLSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG"
     gene            complement(18411..19475)
                     /locus_tag="RFE25_001389"
     CDS             complement(18411..19475)
                     /locus_tag="RFE25_001389"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDU2816458.1"
                     /translation="MKLQTTYPSNNYPIFVEHGAIDHISTYIDQFDQSFILIDEHVNQ
                     YFADKFDDILSYENVHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGAT
                     GDFVGFVAATLLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYRPTAVIYD
                     LDFLKTLPFEQILSGYAEVYKHALLNGESTTQEIEQHFKDREILQSLNGMDKYIAKGI
                     ETKLDIVVADEKEQGVRKFLNLGHTFGHAVEYNHKIAHGHAVMIGIIYQFIVANILFN
                     SNHDIQHYINYLTKLGYPLETITDIDFETIYQYMLSDKKNDKQGVQMVLIKHFGDIVV
                     QHIDQTTLQHACEQLKTYFK"
     gene            complement(19501..20667)
                     /gene="aroC"
                     /locus_tag="RFE25_001390"
     CDS             complement(19501..20667)
                     /gene="aroC"
                     /locus_tag="RFE25_001390"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDU2816459.1"
                     /translation="MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYG
                     RGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMK
                     RTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIY
                     SRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVV
                     QVVVENMPVGVGSYVHYDRKLDGKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEI
                     LYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKAT
                     IERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF"
     gene            complement(21053..21253)
                     /locus_tag="RFE25_001391"
     CDS             complement(21053..21253)
                     /locus_tag="RFE25_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816460.1"
                     /translation="MKNIISIILGILMFLKLMELLYGAIFLDKPLNPITKIIFILTLI
                     YIFYVLVKELIIFLKSKYNKSA"
     gene            complement(21462..21911)
                     /gene="ndk"
                     /locus_tag="RFE25_001392"
     CDS             complement(21462..21911)
                     /gene="ndk"
                     /locus_tag="RFE25_001392"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002463054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDU2816461.1"
                     /translation="MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMEL
                     AETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIR
                     GDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE"
     gene            complement(22003..22962)
                     /locus_tag="RFE25_001393"
     CDS             complement(22003..22962)
                     /locus_tag="RFE25_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002463052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDU2816462.1"
                     /translation="MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVR
                     PAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWD
                     QTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIIN
                     YLRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTE
                     KKLGKPVGSDLLNGHITLPILLEMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDS
                     IDEAKAVSSKYLSKALNLISELPDGHPKSLLLSLTKKMGSRNT"
     gene            complement(22964..23689)
                     /locus_tag="RFE25_001394"
     CDS             complement(22964..23689)
                     /locus_tag="RFE25_001394"
                     /EC_number="2.1.1.163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="demethylmenaquinone methyltransferase"
                     /protein_id="HDU2816463.1"
                     /translation="MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKD
                     MGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKL
                     VHGDAMELPFEDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLP
                     VFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRV
                     RSFTGGVAAMHLGYKEKDNTKGD"
     gene            complement(23692..24264)
                     /locus_tag="RFE25_001395"
     CDS             complement(23692..24264)
                     /locus_tag="RFE25_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heptaprenyl diphosphate synthase component 1"
                     /protein_id="HDU2816464.1"
                     /translation="METTVSKLERQIEERLKGVSEYESININHRLGKLLDSYDIPDVA
                     KVACLTIDTSMRHLDDITYNHLSKHSILIGDLISAHFYTLLAEINDLSFQNEISKAIV
                     EINELKSSLHHQALNDYEISQAIVKIETLFPYITLSHFGINIDESEIYNYLFEDMSDY
                     YPSYFKKYNQSEVKHYLHDIQKSYLKSRGN"
     gene            complement(24695..24967)
                     /locus_tag="RFE25_001396"
     CDS             complement(24695..24967)
                     /locus_tag="RFE25_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDU2816465.1"
                     /translation="MNKTDLINAVAEQADLTKKEAGSAVDAVFESIQNSLAKGEKVQL
                     IGFGNFEVRERAARKGRNPQTGKEIDIPASKVPAFKAGKALKDAVK"
     gene            complement(25138..26136)
                     /locus_tag="RFE25_001397"
     CDS             complement(25138..26136)
                     /locus_tag="RFE25_001397"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDU2816466.1"
                     /translation="MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCH
                     TNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALPTKAMREVATQINDKLTSKKTFI
                     HVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKS
                     VSKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTR
                     GLAEISRLGEKLGADPMTFLGLGGIGDLIVTCISTHSRNFTLGYKLGQGESMDQALSE
                     MNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKECVKDLMERDKKSE"
     gene            complement(26153..27463)
                     /gene="der"
                     /locus_tag="RFE25_001398"
     CDS             complement(26153..27463)
                     /gene="der"
                     /locus_tag="RFE25_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDU2816467.1"
                     /translation="MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYS
                     SGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAIGEADVIIFMVNVREGLTQSDEM
                     VAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVV
                     SHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEY
                     SYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDK
                     RVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERT
                     RLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEP
                     PTFVVFVNDVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN"
     gene            complement(27685..28860)
                     /gene="rpsA"
                     /locus_tag="RFE25_001399"
     CDS             complement(27685..28860)
                     /gene="rpsA"
                     /locus_tag="RFE25_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDU2816468.1"
                     /translation="MTEEFNESMINDIKEGDKVTGEVQQVEDKQVVVHINGGKFNGII
                     PISQLSTHHIDSPSEVVKEGDEVEAYVTKVEFDEENETGAYILSRRQLETEKSYSYLQ
                     EKLDNNEIIEAKVTEVVKGGLVVDVGQRGFVPASLISTDFIEDFSVFDGQTIRIKVEE
                     LDPENNRVILSRKAVEQEENDAKKDQLLQSLNEGDVIHGKVARLTQFGAFIDIGGVDG
                     LVHVSELSHEHVQTPEEVVSIGQDVKVKIKSIDRDTERISLSIKDTLPTPFENIKGQF
                     HENDVIEGVVVRLANFGAFVEIAPGVQGLVHISEIAHKHIGTPGEVLEPGQQVNVKIL
                     GIDEENERVSLSIKATLPNEDVVESDPSTTKAYLENEEEDNPTIGDMIGDKLKNLKL"
     gene            complement(29117..29308)
                     /locus_tag="RFE25_001400"
     CDS             complement(29117..29308)
                     /locus_tag="RFE25_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816469.1"
                     /translation="MSVTNLNIAKEVDLVTKNVLCNNSRKMHYIRSSYYSNVKVAYLR
                     GFLFYKSIKFYYNISCREQ"
     gene            complement(29389..29541)
                     /locus_tag="RFE25_001401"
     CDS             complement(29389..29541)
                     /locus_tag="RFE25_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816470.1"
                     /translation="MQRLTHIQNECADNDLLKLKGDFYSMMNESCLFIFGKSSCVSEL
                     CKFFKK"
     gene            complement(29572..30231)
                     /locus_tag="RFE25_001402"
     CDS             complement(29572..30231)
                     /locus_tag="RFE25_001402"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDU2816471.1"
                     /translation="MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYK
                     YLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKE
                     PVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLR
                     GIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQI
                     K"
     gene            30308..31276
                     /locus_tag="RFE25_001403"
     CDS             30308..31276
                     /locus_tag="RFE25_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDU2816472.1"
                     /translation="MKHLLVIHTGGTISMSQDQSNKVVTNDINPISMHQDVINQYAQI
                     DELNPFNVPSPHMTIQHVKQLKDIILEAVTNKYYDGFVITHGTDTLEETAFLLDLILG
                     IEQPVVITGAMRSSNEIGSDGLYNYISAIRVASDEKARHKGVMVVFNDEIHTARNVTK
                     THTSNTNTFQSPNHGPLGVLTKDRVQFHHMPYRQQALENVNDKLNVPLVKAYMGMPGD
                     IFSFYSREGIDGMVIEALGQGNIPPSALEGIQQLVSLNIPIVLVSRSFNGIVSPTYAY
                     DGGGYQLAQQGFIFSNGSNGPKARLKLLVALSNNLDKAEIKSYFEL"
     gene            complement(31391..32377)
                     /locus_tag="RFE25_001404"
     CDS             complement(31391..32377)
                     /locus_tag="RFE25_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpdA family putative bacillithiol disulfide
                     reductase"
                     /protein_id="HDU2816473.1"
                     /translation="MQKVESIIIGGGPCGLSAAIEQKRKGIDTLIIEKGNVVESIYNY
                     PTHQTFFSSSDKLSIGDVPFIVEESKPRRNQALVYYREVVKHHQLKVNAFEEVLTVKK
                     MNNKFTITTTKDVYECRFLTIATGYYGQHNTLEVEGADLPKVFHYFKEAHPYFDQDVV
                     IIGGKNSAIDAALELEKAGANVTVLYRGGDYSPSIKPWILPNFTALVNHEKIDMEFNA
                     NVTQITEDTVTYEVNGESKTIHNDYVFAMIGYHPDYEFLKSVGIQINTNEFGTAPMYN
                     KETYETNIENCYIAGVIAAGNDANTIFIENGKFHGGIIAQNMLAKKQTPLES"
     gene            complement(32538..>32622)
                     /locus_tag="RFE25_001405"
     CDS             complement(32538..>32622)
                     /locus_tag="RFE25_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816474.1"
                     /translation="AYQLNFLNSHQKDKTPQSTNLTRENKK"
BASE COUNT        10419 a         5946 c         4505 g        11752 t
ORIGIN      
        1 cttgtgtggt gaaatttatg aattatccaa atggtaaacc atatcgtaaa aatagtgcta
       61 tagacggagg gaaaaagacc gctgccttta gtaatattga gtatggtgga cgtggtatgt
      121 cacttgaaaa agatatcgaa cattcaaata cgttttatct taaaagcgac attgcagtta
      181 ttcacaaaaa gcctacgcca gtacaaatag ttaatgtcaa ctatcctaag cggagtaaag
      241 ctgtgattaa cgaagcttat tttcgtacac cttcaacaac tgattacaac ggcgtttatc
      301 aaggttatta tattgatttt gaagcaaagg aaactaaaaa caagacgtcc tttcctttaa
      361 ataatattca tgaccatcaa gtcgaacata tgaaaaatgc atatcaacaa aaaggtattg
      421 tgtttttaat gattcgtttt aaaacgctag atgaagttta tcttttaccc tattcaaaat
      481 tcgaagtatt ttggaagaga tataaagata atattaaaaa gtctataaca gttgatgaaa
      541 tacgaaaaaa tggttaccat attccttatc agtatcaacc aagattagac tatctaaaag
      601 cagttgataa gttgatatta gatgaaagtg aggaccgcgt atgacggaaa acaaaggatc
      661 ttctcagcct aagaaaaacg gtaataatgg tgggaaatcc aactcaaaaa agaatagaaa
      721 tgtgaagaga acgattatta agattattgg cttcatgatt attgcatttt tcgttgttct
      781 tttactaggt atcttattgt ttgcttatta tgcttggaaa gcacctgctt ttaccgaagc
      841 taaattacaa gatccgattc ctgcaaagat atatgacaag aacggagaac ttgttaaaac
      901 attagataat ggccaaagac atgagcatgt aaatttaaaa gacgtgccga aatcaatgaa
      961 agacgcagta cttgcaactg aagacaatcg tttctacgaa catggcgcac ttgattataa
     1021 acgtttattc ggtgcaattg gtaagaactt gactggtgga tttggttctg aaggtgcctc
     1081 aacattaaca caacaagttg ttaaagatgc atttttatca caacataaat ctattggacg
     1141 taaagctcaa gaagcatact tatcatatcg tttagaacaa gagtatagta aagatgatat
     1201 cttccaagta tatctaaaca aaatttacta ttctgatggc gtaacaggta ttaaagctgc
     1261 tgctaagtat tactttaata aagatttaaa agatttaaac ttagcggaag aagcttattt
     1321 agccggttta cctcaggttc caaacaacta taatatttat gatcatccaa aagctgctga
     1381 agatcgtaaa aacactgttt tatacttaat gcattatcat aaacgcatta cagataaaca
     1441 gtgggaagat gctaagaaaa tcgatttaaa agcgaactta gtaaatcgta ctcctgaaga
     1501 acgtcaaaac attgatacaa atcaagattc tgagtataat tcatacgtta actttgtgaa
     1561 atctgaatta atgaataata aagcattcaa agatgaaaat ttaggtaatg tattacaaag
     1621 tggtattaaa atttatacaa acatggataa agatgttcaa aaaacattac aaaatgatgt
     1681 tgataatggt agcttctaca agaataaaga ccaacaagtt ggtgcaacga ttcttgatag
     1741 taaaactggt ggtttagttg ctatatctgg tggacgtgat ttcaaagacg tcgttaacag
     1801 aaaccaagca acagatcctc accctactgg ttcatcttta aaacctttct tagcgtatgg
     1861 acctgccatt gaaaatatga aatgggcaac aaaccatgcg attcaagatg aatcttcata
     1921 tcaagttgac ggttctacat ttagaaacta tgatacgaag agtcacggta ctgtatctat
     1981 ttatgatgct ttacgacaaa gtttcaatat cccagcttta aaagcatggc aatcagttaa
     2041 gcaaaatgct ggtaacgatg cacctaagaa attcgctgcc aaacttggct taaactacga
     2101 aggcgatatt ggtccatctg aagtacttgg tggttctgct tcagaattct caccaacaca
     2161 attagcatca gcatttgctg caatcgctaa cggtggtact tataacaacg cgcattcaat
     2221 tcaaaaagta gttactcgtg acggtgaaac aatcgaatac gatcatacta gccataaagc
     2281 gatgagtgat tacactgcat acatgttagc tgagatgcta aaaggtacat ttaaaccata
     2341 tggttctgca tatggccatg gtgtatctgg agtaaatatg ggtgctaaga caggtactgg
     2401 tacttacggt gctgaaactt attcacaata taatttacct gataatgcag cgaaagacgt
     2461 gtggattaac ggctttacac ctcaatacac tatgtcagtg tggatgggct tcagtaaagt
     2521 taaacaatat ggtgaaaact catttgtggg acatagccaa caagaatatc cacagttctt
     2581 atatgaaaat gtgatgtcaa aaatttcatc tagagatggc gaagacttta aacgtcctag
     2641 ctcagtaagt ggtagtatcc catcaatcaa tgtttctggt agtcaagata acaacactac
     2701 aaatcgtagt acacacggtg gtagtgacac atcagcaaac agcagtggta ctgcacaatc
     2761 aaataacaat actagatctc aacaatctag aaacagcggt ggattaacag gtatattcaa
     2821 ctaatccact caacataaaa tcctcagtta taccatattt atggtgtagc tgaggatttt
     2881 tttaggttct tcatctttta tggtgggaag gtaaaacttc ctgctttttt tataagtatt
     2941 catacgctaa tgctatatta gtagaaaccg taaaatcagt cattcacata cattttgaaa
     3001 catctaaata gtttttcata ttcacatctt tagctatgta aaattattga atttgaataa
     3061 gtggttgttc ccatttttaa aattatgatt atattttctc atagtcatct tagacgctgt
     3121 tttaaattga aatgtttatc aattccctgt gtacgttaat cagtgaaata tcaagatgtt
     3181 tgcaacatat tttcacaatc atagatataa gaaatccacc tacgattcga aataggtatc
     3241 ttaaagcata tctcaagata tccattatga tgtagatgga cagtttttat attaagacgt
     3301 tgtaatgaca cgacacctaa cataaataca aatatgtgtg catgaattag ttttacatat
     3361 tttcaacatt aagaaatgat caatcttgtc tatacctgct tattctttaa ccttgtttga
     3421 taactagcat tcattttaat caattcagtt ttaaaggtct tcatttgtcg atagcccata
     3481 aaatgatatt tacgttcaat catataatca tatctttctt taaaattcat tggcacaaca
     3541 ggatattgat ttaaattatc aaaatcaata ttgctagtta tgtcattaac ctgcttaaaa
     3601 taatcaataa ttttactatg gtattcatcc aagtagggct ttgcttcact agaacctaat
     3661 gccttatttt tggcaaatac atcaatctct tgttctaaat tatcaaatac ctcttttgta
     3721 atatttgtca tgttatcacg cttctttcaa actagcttta taacgttttt gtccttctct
     3781 acaatcttct aatagtggac aaatatcgca tttaggtttt cgggctaaac agtggtatct
     3841 tccaaagaaa atgagttgat gatggctcct attccatcta tctctaggta tgacagaaca
     3901 taaacggtct tctacctgtc tcacattatc tttccaacga ttaataccta agcgtttaga
     3961 aacacgttct acatgcgtat caacagctaa tgaaggttca tcaaatgcta cactcatgac
     4021 tacattagca gttttacgtc ctacacctgc taaactttct aattccttat gtgtttgtgg
     4081 tatttctcca ttaaattgat caatcaaaga ttgacaaagt ttcttaatat tcttagcttt
     4141 gttacgatac agaccgatag aacgaatatc attcattagt tcttcatcac tgactgccaa
     4201 ataatcttca ggcgttttgt attttttaaa cagctcagtt gttactctat ttactagaac
     4261 gtctgtacat tgcgctgaca ataatacagc aatagttaat tcgaacggat tatcatgttt
     4321 taattcacat tctgcatccg gaaacatatt tgctataaca tcaatcattt ctaatgcttt
     4381 tttcttactt accatcaagg ttctccccgt ttaaccaatc aaatttaggt accgttttaa
     4441 ctgtgtgcgt cattttcggt ttattaaatt tttctcttat ttttctagaa tcgtcaattg
     4501 ttttgacatt gtttttcttc caattaagta aaatacgatc catatattta aagctaagtt
     4561 tattcaaact attcgcctcg tctaatgccg cttgtataat tgcactatcg tgtttatcaa
     4621 catcaatcca ttgatttaac gtttctattt catatggaga taacggcctt gcaaatgtat
     4681 cctctaaaac tctaaataat tgtttaaatt tttctttact attttgctct ttcgtttcca
     4741 tactttgttg cttcaatata tgacttaatt tttcgaaaaa aggatctaga ttcatatatt
     4801 cggtaaatct accttcttca tctttttgaa cttgtaattc tagcaattca cgttgtatca
     4861 aattttgaat aaccattgta atatcacgtg gttgcatagt tgagcccttc tgaagtaatt
     4921 caattgaagg ctgtttattt gatgtttcgg aagcataaat caatttaagc aaaatgacta
     4981 aatcttgctc atctaaacct aagtcactgt aatggtctaa taattctctt cgtatcacta
     5041 caggtcttgc ttttaattga tatttatcca tgttcgtgcc cccttttaaa tttaaccatt
     5101 acttaatagt ataaatcatt ttctttaatt ttcgactaaa atgcttaata tatttaacta
     5161 gtagcaaaca aattttaaat aacagtattt tttaaaacta gattttaaca atgaacttta
     5221 tggataatca gatgaactat ttattttcca aatatagtta ctaaacaaaa gtttgttcat
     5281 gattaatata agccgttatc aatcttcatt ttgcaagcat aaatcgccca gctattaata
     5341 taggctggac gattcttttt attatcataa tataaatttt aagtaacgat cctaaaactt
     5401 atggatataa acggtttaat aatcttggga atggcgcagt ttcacgaacg tgttcaacac
     5461 cagaaatcca tgctactgtg cgctctaaac ctaaaccaaa tccacagtgt ggcacactac
     5521 cataacgacg taagtctaag tagtaactat atgcttcttc gtctaatcca tgttctttaa
     5581 cgcgttgttc taacaattct aagtcatcca cacgttcaga tccaccgata atttcaccgt
     5641 atccttcagg tgcaattaag tctgcacata agacagtttc ttcattctca ggatttggtt
     5701 gcatatagaa aggcttaatt ttagttggat aattagtaat aaacaccggt aaatcataat
     5761 gattagcaat ggcagtttca tgtggcgcac caaaatcttc accccattca atatcatcaa
     5821 agccttctgc ttttaagaat tcaattgcat catcatatga aattctaggg aatggtgtcg
     5881 caactttttc aagttttgat gtatcacgct ctaaaatttt caactctagt ttacaatttt
     5941 ctaaaactga ttttactaca tgtgttacat attgttcttg aatttctaaa ctttcagcat
     6001 gatttgtgaa agccatttcc ccttcaatca tccagaactc gatcaagtgt ctacgtgttt
     6061 ttgatttttc agctctgaaa gttggaccaa atgaaaatac ttttccgtgt gccattgctg
     6121 cagcttctaa gtataactga ccactttgag ataaaaacgc atcttgatca aagtatttag
     6181 tatggaataa ttcacttgta ccttctggtg cacttgctgt caaaattggt ggatcaacct
     6241 ttgtaaatcc atctttgttg aaaaattcat acgttgcacg aataacttca tttctaattt
     6301 tcattacagc atgttgtttt ttagaacgta accataaatg acggtgatcc attaagaatt
     6361 ctgtaccatg atttttaggt gtaatcggat agtcatgcgc ttctgaaata acttcaattg
     6421 atttcacttg catttcgtat cctaagtcag aacgattatc ttctgtaatt gtgcctgtaa
     6481 cgtatagaga tgattcttga gcaatttctt tcgcaagttt gaatacctct tcatcaactt
     6541 ctgatttaac tactacgcct tgcataaagc ctgttccatc acgtaattgt aaaaaggcga
     6601 ttttaccact tgaacgttta tttgttaacc aagcaccaat tgtaacgtct tggtttaaat
     6661 gatctttcgc ttgtttaatc gttgttttca taaccattct cctatttatt ttttcgttat
     6721 acaatactca ttcattttaa caaaatccgc tttcaagttc tagaactaga ctaaaagata
     6781 acgtgtaaat ggtaatgatt tacgcacaga tttgaacatt aatttatatt aagacaatac
     6841 aatcatcagt ttcagacaaa atatataata aagcctcaat attattagta tgaaggtcgt
     6901 tttttgtgct aacattcaag tttaattata aaactcaaat tttgacgacc aaacaaaaat
     6961 tcttgtaaca gaacatagca catgtcatgt cacaagaatt ttactttgta tttcactttt
     7021 tctttttttg aatttgtctt aataattttc caaactgttg aatgtcgcct tttttctgac
     7081 gataattttc aagtgtttgt tcaaaaaagt ttttataatt actgtttatg agtcgatcat
     7141 caaatgaaac tattatgccg cgatcatttt catttctaat taatcttcca agtccttgtc
     7201 taaaacgtgt aactgcatca ggtaatacat attccttgaa agttgaagtg aattcagaat
     7261 ccataagcca atattttgca ttatgcttgt tcataaacgg taacttcgct atcatcacac
     7321 atttaatacc atttgcttga aaatcaaaac cttcaaaaaa tgttgacgta ccaagcagta
     7381 tggccttatc aaaattatta aactgttgta ctattttata attttggttc tgctgttgtg
     7441 ttaatacaac ataatcttca aattctggca attcatttag catatcttgt accatatgca
     7501 tcattttata actcgtaaat aagactaaac attttgatga cgttatagtc gtatattcaa
     7561 taatatagct tacaatcgat gctacatact catctatatt tttatattga taagatgcta
     7621 catcactcgg tataaataca cttgtatttt ttgcactttg taacgacgtg ttaacttcaa
     7681 atgtattaaa gtgaacatct ttgttgaata actgtttaaa agcttcaaac gaatgattaa
     7741 attttaaagt accagatata aaaatgagtg atttaaattt ttccaatact tgtttcgtta
     7801 atacatcttt tacagcgtaa tctttcacat ataaacgtat tgttgatttt tgagataaat
     7861 ttttaattga aatgaaacta gtatgtccag cttttaaact ttgttcgata tttttaaatt
     7921 tatcttttaa atacaacaac tgtttccgta atgatttaac tgttttatga ctaatgccat
     7981 tgaatatttc tagcgtttta tttaacttat cgataatcgc atgtaaatcc ttcaaaatgt
     8041 cttttgtttc aaaagtaaat acattatgga agcgatgaat atcatcatca taaacatcag
     8101 aatcattgat aatcgtaaat atcgttgaga acaattgctc atttaactca tgaatctcat
     8161 tcatactagc cttcaagcca aaaatatcaa ttggtgcaat atctaatttt tccaaaattc
     8221 gttgcttttc cagttgatcg attgccttta acaatttttc attttcgttt ttaccaatca
     8281 aaccaagctg atatttaata tcagcataac tcaactcatt tgtcacttga tttaaggcat
     8341 agtctggtaa gcgatgtgct tcatccacta tacaatcatc aaacaattga tatattgaat
     8401 tttcaacatc agaatgaatt aaatgtgcat gatttgtaat accaatttga atgttctgtg
     8461 catttcgctt aataaaatta taataatgaa catcgtgacg tgccggtaca tatgtttcaa
     8521 ttttctggtc aaaatacatc ttttgaccac cttttaaatt taattcctgt atatctccgg
     8581 acggcgtctc tgtaatccaa attaacaatt gcattttcaa gatattcact tcgtaattac
     8641 ttgtgtcatc ttttaaaatt tgactaataa gtcccaatga aatgtaatca cttttacttt
     8701 taatcaatag tgcattaatt ttaaaattta acgcttcatt cattgctgga atatcttttt
     8761 ctaacaattg actttgcagt aatttagtat tggtagaaat catgacatgc ttcccagttt
     8821 caatattata catcaaggcc gcaagtaaat atgctaatga tttaccactg cctagtgatg
     8881 cttcaatcat tgctttttca ctatgcatga gctgatctaa tatagtttcc gctaaatata
     8941 attgttgcgg tcgatatgtt aagccaagtt gatctacagc tttgctatat aaagacttca
     9001 agctgccatt ataatttgtt gtcggctttt taaaatcaac ttgcttacga tagataatct
     9061 gttcgaactt ttcgtacgat ttatccaatg gctttgcatc atattgccta accatctcaa
     9121 agaaaatatc atacaaatcg tatttcaact gtttacttaa ataatataat tgcttcaaag
     9181 tatctaacgg taacttttca aatttttcaa aagctaatat catcaattta gcagtagtag
     9241 cggcatcttc gtcagctcga tgggcatttg ctaaggtaat accatgtgcc tctgctaatt
     9301 cacttaattg atagctttta tctgtaggaa aagctatttt aaagatttct agtgtatcta
     9361 taactttttt gggacgatat tgaatattac aatctttaaa tgccttttta ataaaattca
     9421 aatcaaaatc tacattatga gcgacaaaaa tgcaatcttt tatcttatcg tagatttctt
     9481 gtgcaacttg attaaaatat ggcgcttgtt gtagcatatt ttcttcaatg gatgttaacg
     9541 cttgaatgaa cggcggaatc tctaaatttg ttctaatcat agaatgatat gtatcaataa
     9601 tttggttatt gcgcacaaac gttataccaa tttgaatgat atcgtcaaaa tctaattggt
     9661 tgcctgttgt ttccaaatcc acaacggcat aggttgccat acccatagct atctctcctt
     9721 gctttagtgt taaaaatcta tatctgcact aattaaacgg tgtgattcac ccgcttcatc
     9781 tctaacaatt agatagccat cgtaatctaa atcaattgct tgtcctttaa actgtttatc
     9841 attttctgta aatagcaacg ttctattcca aatattagaa gctgcaatat attcttcacg
     9901 aatttcagaa aaaggtaacg ttaaaaattg attatatctt ttttcaattt cttgaagtaa
     9961 tctctctaaa aattgatatc tatctaattt atttttatca tgtaattgta tacttgttgc
    10021 tctatgtcta atactttcat caaagttttc tagttgttgc gtcaaattaa tacctatacc
    10081 acatattatt gcttctatac catcattatt agcaaccatt tcagttaaga aaccacacac
    10141 tttaccatta tcaatatata tatcattcgg ccatttcact ttgacttcat cttgactaaa
    10201 atgttgaatc gcatctctta tccctaatgc aataaataaa ttaaatttag atatcattga
    10261 gaatgcaacg ttaggtctta acacgacaga catccaaagt ccttgccctt ttgaagaact
    10321 ccaatgtcta ttaaatcgcc cacgaccttt cgtttgttca tcactcaaga taaaaaatga
    10381 agattgattt ccaacaagtg actttttcgc agcaagttgt gtagaatcta ttgaatcgta
    10441 tacttcacta aaatcaaaca aagcagaact ttttgtatat tggtctatta taccctgata
    10501 ccaaatatct gggagttgtt gtaataaatg ccctttatga tttactgaat caattttaca
    10561 tccctctaac tttaattggt caatcacctt ttttactgca gtgcgtgaaa tattaagtga
    10621 ttccgcaatg ctttgtccag atatataatt cggtttattt ttatagagta attgaagtac
    10681 atcttgacta tattttgaca tgattatcca cccatttcaa aatttcagtt tcttcgttgc
    10741 ttactttacc tgttacaatc gctatctcaa tttgtcttag cacatctttt aaccacggac
    10801 cacttttggc atttaaatgt gccataagta caccgccatt aaccatcatg tcttttctat
    10861 tatgcatagg taaacgatgt aatgtttcat caatcgtttg aaggttaacg attaatggtt
    10921 catgtccttg aatatcattt gcctttaaca cgtctgctgc aaccattaca tttttaatga
    10981 gattcgtatc ataatcataa acaaacattt ttaattgttc ttttgtaata atacttggta
    11041 atgcattcat aatttgaata tattgattga tatcttttac ttgtcggtta cttagcttta
    11101 aaggcttcaa tgagtaatta atatcaaatt taactgacac tatagcaatc aacaattcta
    11161 aatcaattgg ttcagttaca ttaatttgat tcatatcaag ttgttcgaaa tatggcatat
    11221 aattaaatgc tttcagcgat tttaaatgat taaaactctc ttcaacatta atacctcgca
    11281 ttaatttagt tagttcaatc actatacgct caattgataa aaatttaata tctgccattt
    11341 gtgtacgcat cgcttcaaat gtttccattg caatatcaaa tgataattgt gactggaatc
    11401 ttaaacatcg aatcatacgt aaagcatctt cttggaatcg ttcctcagct atacctacag
    11461 ttcttattat tcgattatta atatcttgtt gaccatcaaa ataatcatac aatttgtatg
    11521 ctgtatccat tgctatcgca ttcatcgtga aatctcttcg ttgcaaatct tcgtataaat
    11581 cccgaacaaa tgtaacacca cttggtctac ggtgatcgac ataatcttct tcagcccgga
    11641 atgttgtcac ttcataattt tcatcattaa aaactacatt tatggtgcca tgttctttac
    11701 ctacaggtat cgtatgacta aagatagatt ctatttcatc cggcgttgca cttgttgtga
    11761 tatctatatc atgaatattt cttcccatga cataatctct tacagagcca cctacataat
    11821 atgcttcaaa accattgtct tgaatttgtt ctaatatagg ccttgcctgt tcaaataatg
    11881 atttatccat attattactc gcctttactt ttgttatgct catttagcat tttttgataa
    11941 taatactcat attgatctgt aataagttct gatccaaaac gttcagcaat atctgctagc
    12001 atgtttttct gaagtttgtt gtataacgcc ttatcttcaa gtaaacggat agcatagtca
    12061 ctcgctgaat cacaatcacc cacatctaca acaaatccag tttcaccatg tttaataacc
    12121 tctttaattc caccggcatt tgaaccaatt ggaacgacgc ctgttttcat agcctcaagt
    12181 aaagttagtc caaagctttc tttttcactt aataataata ctaagtcaga taattgataa
    12241 aattcactta cacaatcttg tttccctaaa aataaaacat cctcttctac gtttaactct
    12301 ttcgtcaatt gacgcattgg cactaattca ggaccatctc caagtaaaat taatttacta
    12361 ggtatctttt cacgtacttt tgcaaatgtt tctataatag tatctatgcg ttttacttgt
    12421 ctaaaattcg atacatgtat taacactttt tcatctggtg ctataccaaa ttgtgatttt
    12481 aatgctgtgt tatgtttagt tggaaactca ttttcacgta caaaattata aatcggtata
    12541 atttctttgt tagtttcgat aatttcatgt gtttcttgcg ctaaagattt actcacactt
    12601 gtcacaatat cacttttttc aatgccaaat ttaattgcac cttggagtga atgatcatag
    12661 cccaaaacag taatatcagt accgtgtagc gttgtcataa tttttatatc tttacctgac
    12721 atctcacgag ctaaaattcc acaaattgca tgaggtacag catagtgcat atgcaacaaa
    12781 tcaagatcat attctttaat aacttcagcg attttagtac ttaacgtaat atcatacggt
    12841 ggatattgaa atactgcata ttgattcact tcaacttgat gaaaaatcat attcggcaat
    12901 ggttttctta ttctaaacgg gatatttgaa gtgataaaat gtacttcgtg acctcgctct
    12961 gctaatttaa ttcctaattc tgtggcaata attccagaac cacccatgga cgggtaacat
    13021 gttataccta tcttcattcg cttgcccatc ctttctttct atttctcttt ctattattct
    13081 cgatgcgtag ataattgttt aaatttaagt ttatagtaat gttgagttta taatttcaaa
    13141 tatctaaaaa acaggtgttg tatatataat catttatcta gttctactta ctttaaaaat
    13201 aatataattt catgcgatgc aattcattgg tctatgtttt taatcttaat caaatccaaa
    13261 taaagcatat atttttaaat tcactttctt tcgaatcgat ttttatctct tgtattaaac
    13321 ttttccattg tttcattaaa gctctctgtc atatctattc ccattgaatt cgctaaacat
    13381 aacaacacaa ataaattatc acctaattct gctttaatcg tatttgcttc ctctgaatct
    13441 ttcttctttt tttcaccata ggtatgattt atttcacgtg caagttcgcc cacttcttca
    13501 gtcaatctag ctaagttagc taatggtgaa aaatatcctg ttttaaattg tccaatatat
    13561 tcatcaactt cacgttgcat ttctaccatt gatttcattt ctacgttctc cttatattgc
    13621 atttctaata tagtatatat caatttgaag tctcatgcat gtttagtgca atctactgac
    13681 tctagctaaa ctagatgaca agttgtttat tttagaagtt taataattca gtttatataa
    13741 atgtaatgca ttcctaacta aattaaatca attgaaattg ggattataac tttatgattc
    13801 gtaccactac aataaaataa tataatgaat aatctaccat tagaaaaata agcacaaaaa
    13861 aactagcaat cacacaaaat gtgattagct agttaataag tgtctaattt aagttaattg
    13921 ttaatctata agattaatca cttgaacgcg caatcaaaat aatacgtaca agctctgcta
    13981 cagcgacagc agttgctgca acataagtca ttgctgctgc agataatact ttacgcgcat
    14041 gcttgtattc tttttcattt acaatgttca atgccgtaat ttgtttcatc gctcttgaac
    14101 tcgcatcaaa ctcaactggt aacgtaacaa ttgagaataa taccgctaat gacattaaac
    14161 cagcaccaat ccataaagca gttgaaccaa atgcactacc tatcgctgtt aagataatac
    14221 ctaacatgat gatcatataa cttaatgaac tccctaggtt tgcaacaggt actaatgctg
    14281 ctctgaatct taagaaccaa tatccttggt gatcttgaat ggcatgacca acttcgtggg
    14341 ctgcaattgc agttccagca actgatggtc tgtcatagtt tgcaggagat agtgaaacaa
    14401 ctttcttttt aggatcgtaa tgatctgtta agaatccttc acctttaaca acttcgacat
    14461 cataaatacc gtttgcatgt aaaatttcta atgcaacttc acgacccgtt ttaccactag
    14521 ttgatctaac ttgtgaatat ttctcatagt tagatttaac tttgtgttgt gcccataaag
    14581 gaagcaccat taatattacg aaataaatta tcatagtaaa aattgaagac aataaactca
    14641 ctctccttta taaatatttt actgtcattt gccgttttta tcaaatcatt tacactttaa
    14701 taatttgttt aattcaatat aaagcaaaag tccaaaaaca cttagacaac atgataatac
    14761 accaatttgc cacacatgtg tagttataaa atcataatat ggaaattgaa ggtgaaaata
    14821 gtcaatataa tcattcaaaa acacccaaat catcgctaca ctgattccaa tcatagaacg
    14881 tttaaaccta ggatagaagt aaattgcctg aacagccatt atactgtggg aaaacattaa
    14941 taccaaacca tttactgtaa tatcaccttg ttcaataata aataatatat tcattataac
    15001 tgcccaaatc ccatatttga ataatgttac aaatgccagt gcttcgataa tactattttg
    15061 tttttgaatt aatatcaatg agatagaaat aactaagtat aatattgcag ttgggctatc
    15121 tggaacaaaa atcttaaaat gccacggcgt atgacttaat tgttcaccat accatatata
    15181 accataaatc atccctaata tattacaaat gagtagcatc attaaccaag aacgttgata
    15241 aagtgtatat tgccaaaatg tattaatcgt catctgctaa gtcctcaaat tgattatgtt
    15301 tatttactag cttgagtgta tttaaaattt gcgttagttg ataaaaacgt tgcttttcat
    15361 tcatctgtaa acttaaatca atattgtgta acaagtaatc tattaataac gcatgtttat
    15421 gccgatctat agccatacta tttaagtcat gaagataagt ttgataactg ggcgattccg
    15481 ttagttgagc aactattaaa tcatctagcc tttgctcacg ctttgacacg tttgcgaagt
    15541 gaatttgaat atcaaaagca cagttatgat tagcgatata atcaaatatt tcatttgtat
    15601 tcattaactt tatattacgc ttagtaaatt gaattgcaga agcgtgactt cccacttctg
    15661 caatttctaa tgtttcatga tgattaattt ttgtatctac aaaatgaatg tttgccaatt
    15721 tcgcctcatt cacttttata tagttaagca cccaaactgc aatacgcgac ttaaatcgat
    15781 attgaaaaag taaatattca ataaaacttt ctttaatttg attgagtgtc tctgacatca
    15841 aataccccat tttaagattg caatcttgat aattcgtcat gccaattttc gttacttggc
    15901 tctagttcca acaattgatt taaaatagta attgcttgtt ccttttgacc aatttcaatt
    15961 aaatagaaat aataatcact cataaaatca atatttgttt tcatcgttgg atatgctaat
    16021 tcaaagaaat gttgagcttc tttatctcgc tcttcttgac cataggcgaa cgctaaatgc
    16081 cacatgaatg taggatccaa atcttcttca tctacatatg ttaataattc aatgattgct
    16141 tcataatctt cttcattacg atataaatcg cttaaaatca ataaaggttc ttggtaagca
    16201 ttatcaacct ctaatgcttg ttttaacaat aatacacctt cattagcatc gccgtgttct
    16261 atttccaaac atccagttgt atacattaac tctttataaa attgacttag tcgtaatcct
    16321 tctttacccg tctcaatggc atctggataa tttttttcat tttcatataa tgattgtaaa
    16381 tacaagtagc cttgaatata atcaggatct ttagaaagta atgtagtcat tattttaatt
    16441 gcttcttgag tgatgtcatt tttatcgtaa gaaatggctt ttttgagata atcttctgaa
    16501 gtcatttcat cttcattaat ttcatcgtat aagcgaatcg catcactata gttaccactt
    16561 tgtaaactac aatctgccat acgagagaat aagtttacac cattaacttg atattcacca
    16621 gtttctaaaa cggtttcgta ttcagaggta gcacgtaaat attgaccatc ataatataac
    16681 atttcagcca atgcaaaatg gattattgga tcatttggct ctagttcaag tgcttcttgt
    16741 aatttatcaa tagcaacttc catcatatta atttgttgat ataaatctgc ttctaacatc
    16801 aacttttcag gtgatggttc aacataactt aaatattcta acgcttcgtc agtttgattt
    16861 tcagacatta aaccttcaat aaaataaatc agcaattcac tttcgtctgg atatttgtga
    16921 tataacacgc ggaatacttc caaaccttgt ggcattaatc caaaattgta aagtgtctct
    16981 cctagaataa ataatgcgtc atcgttgtca gtagttattg cttcattaac acgagagtct
    17041 aaattttcta gtttttgtag attgatatcg tctattaatt tatagatatc ttccatttta
    17101 tattatccct cattttctaa aagctttagt tttggtaaaa atcctggaaa tgatacattt
    17161 acagcatcaa attgtttgat tttgacaggc tcgcttgaaa gtagagaagc aactgcaagc
    17221 atcattccta ttcgatgatc agttaaacta tcaactgttg catttgtttt aaattctgac
    17281 ggatgaataa tcaatccatc attagttggt tgtaattcaa accctaacaa gtttaacata
    17341 tcagccgttg tatcaattct atttgtttct tttactttta attcctcggc atctttaatt
    17401 gtactcgtgc caactgcttg tgtacaaagt aatgctatta caggcagttc atcaattgct
    17461 tttggaacta attctccttc gattgttatt ggttgaagca ttggtgtgta ttgaatacga
    17521 atagaagcag taggttcagc accagttgtt tgattgaaaa gttggatatt accgcccatt
    17581 ttttcaacaa tatcaataat acctgaacgt gttggattga ttccaacatt atgaattgtt
    17641 acatcacttt ctggtgtgat aagtgctgca acaataaaga acgctgcaga tgaaatatcg
    17701 ccaggaacat gaaaatctgc aggtttaata tgttgaatgg catcaggggt tgtagttatt
    17761 gataaccttt ctgcttcaat tggaatatta aaatgtctga acatcgtctc agtatgattt
    17821 cgacttacat ctaattcctt tattaccgtt gtatcatttg aaaacaaact tgcaaataaa
    17881 atggcacttt ttacttgtgc acttgcaact tccatttgat aatttatacc ttttatgaca
    17941 gatggcttaa taattaatgg tgtataatta tcttcaatac cttcaatatt cgcatccata
    18001 agtttcaatg gtctcaagac acgatccatt ggccttttac caattgaaac atcgccagac
    18061 aaaacacttt caatacctaa accacttaac aaaccagcta acaatcgagt cgttgtgcca
    18121 gagtttccag tatataaaac ttgatgaggt gttttaaaag ctttatatcc aggtgaattc
    18181 acaaccaatt tatcttcatc ttctttaata tctacgccta ataatcggaa tatatccatt
    18241 gtacgacgac aatcttcacc aagtaatggt ttataaatat tggaagttcc ttcagctaaa
    18301 gatgctaaca tgattgctcg atgtgtcatc gacttatctc caggcacttc tatttcacct
    18361 ttaagtggcc ctgaaatatc gataatttgt tcacttacca tttacttcac ctacttaaaa
    18421 tatgttttta gttgttcaca cgcatgttgc agtgttgttt gatcaatgtg ttgcactaca
    18481 atatcgccaa aatgtttaat caataccatt tgaactcctt gtttgtcgtt ctttttatca
    18541 cttagcatgt attgatatat cgtttcgaaa tctatgtcgg ttattgtttc taaaggataa
    18601 cctaatttcg ttaaataatt aatataatgt tggatatcgt gattagaatt gaacaatata
    18661 ttcgcaacaa taaattgata tattatgcct atcattacgg catgaccgtg tgcaattttg
    18721 tggttatact ccacggcatg accaaatgta tgacctaaat ttaaaaattt acgtacacct
    18781 tgttcttttt catctgcaac aacaatatcc agcttcgttt caataccttt agcaatatat
    18841 ttatccatac catttaatga ctgtaatatc tctctatctt taaagtgctg ttcgatttct
    18901 tgcgtcgttg attcaccatt caataacgca tgcttataaa cttctgcata gccacttaat
    18961 atttgctcaa atggtaacgt ctttaaaaag tctaaatcat aaatcacagc agttggacga
    19021 taaaatgcac cgataaggtt tttaccttgt tttgagttaa tacccacttt accgccaaca
    19081 ctagaatcat gcgccaaaat cgttgtagga acttgtataa aatggacacc tcttaatagt
    19141 gttgctgcta caaatcctac aaaatctcct gtcgcaccac caccaacagc tataatcgct
    19201 gtattacgcg ttacatgatg tgacaaaatg tattctaatg tttcttgata ttgctcaaat
    19261 gttttcgtct tttcaccagc tggaataatg actttatgca cattttcata tgataaaata
    19321 tcatcaaatt tatcagcaaa atattgattt acatgctcgt caattaatat aaaactttga
    19381 tcaaactgat caatatacgt gctaatatgg tcaattgcac catgttcaac aaatattgga
    19441 taattgtttg aaggataggt tgtttgtaat ttcatgatca cacctcaatt gttctcgttg
    19501 ttaaaactca acatttaatt gtctgcggtc agcaatttgt tgttgaagtt gttcaatatg
    19561 gtttgattga aactcttcaa gtaatgcttt cgctatttca aatgcaacaa cgtgttcaca
    19621 cactatactt gctgcaggta cagcacaact atcagaacgt tcaattgttg ccttaaagtc
    19681 ttctttagta tttatatcaa ctgaatttaa tggtttatat aacgtaggaa taggtttcat
    19741 tacaccattt acaataattg gcataccatt tgacatacca ccctctaaac cacctaaatg
    19801 attagatcca cgataataac caatttcact attatataga atttcatctt gaatctcact
    19861 acctggcttt tcagctgctt taaatccttc tccaaagctt acacctttaa aagcatttat
    19921 gctgacaaca ccttgtgcaa tcttaccatc taacttacga tcataatgca cataactacc
    19981 aacaccaaca ggcatatttt caactacaac ttgaacgaca ccgccaattg aatctccttc
    20041 atttttagct tcgtcaattt tatctcgcat tgcttgtgcg atactgtcat caattacacg
    20101 aacatcatta cgatcaagat ttgctttaaa tgtttctgaa tcataaaaat ctttatcttt
    20161 aatgccacct atttcaacaa cacgactgta tatatcgata tctaactgtt gtaataacac
    20221 tttacataag gcaccgactg caactcgagc tgctgtttct ctagcagatg atcgctctag
    20281 cacatttcgt aaatcacgat gattatattt catacctcca accaaatctg catgaccagg
    20341 tcttggtttt gtaatagtac gtttcatatt ttcacgttct tcttcactta ttggagctgc
    20401 tcccataatt tttctccaat gcgtaaagtc atcattggtt acaaccatag taattggact
    20461 acctaatgta taaccatttc taacgcctga tactatttct actgtatctt tctcaatttg
    20521 catgcgtcgg ccacgaccat aacccccttg acgcttgaac atttctttat taatatcttc
    20581 aactttaatt tctaaatttg ctggtatacc ttcgacaata actgttaatt gaggtccatg
    20641 tgattctcct gaagttagat atctcataca cactcgctcc tttcatactt ccgcaataac
    20701 attataatat gttgttaatc ttatcacatt cattgtggat tcataaatgt ttgttttcaa
    20761 gcttaattaa gaaaatggat gacatctcat tttaaatgtc agaattatct taatattaaa
    20821 cgaactaaaa ttaattataa tatattcgtc tgtagaaaag tatcatgaat ttctaaacag
    20881 ttgcatcata taatcattaa ttaaaaatga ttagccgttt taatataatc gtatcgcaac
    20941 tttagcaaat aatatactga ctacatttct taatacaaaa gaacgaactg ttaattatta
    21001 ataaagttaa tcagtccgtt taaaaaaatt atgatattaa aatatacata tgttaagcgc
    21061 ttttgttata ctttgacttc aaaaatataa tcaattcttt tactaataca taaaaaatat
    21121 aaatgagagt cagtataaaa ataatttttg ttataggatt aagtggttta tctaaaaata
    21181 tagcaccata tagtaattcc attaatttta agaacattaa aatccccaaa ataatcgaaa
    21241 taatattctt cattttaaca accccttctc tctgtttagt ttcatttgat aaagaatatt
    21301 cctctctttt taatacgtgt taccaaaaaa ctataaaatt tttcaagtaa tttactacaa
    21361 cataaaaaac gggccttgtt atgtataatc ataatgacta accacataac aaaacccttt
    21421 ctacctttat aaataaatcg taaaggttta cagtttatat tttattcata taaccatgca
    21481 tcacgtggtg aagcatagct agtaatttca ttttcattaa accatagatt aatttcacgt
    21541 tcagcagact ctaatgaatc tgaaccgtga atgatatttc taccaacagt taaacctaaa
    21601 tcacctctaa ttgatcctgg tgaagcttct gaaggattgg tgctgccaat aatatgtcta
    21661 gatacattaa ctgcatcttc accttcaact accattgcga acactggtgc tgatgtaata
    21721 aatgaaatta aatcattata aaacggtttg ccttggtgtt caccataatg tgtttcagca
    21781 agttccattg gtacttgcat taatttacca ccgacaagtt ttagtccttt tctttcaatt
    21841 cttgaaatta cttcaccaat tagatttctt tgtactgcgt ctggtttaat cattaaaaat
    21901 gtacgttcca ctttatgtat ccccctgtgt ttaataggtt tatgtatatt actattatat
    21961 attaacaggt tggtaaagcg ctttcaatac ttttcataaa tactatgtgt ttcttgaccc
    22021 catttttttc gtcaaactta aaagtagtga tttcggatgt ccatctggta actcagaaat
    22081 caaattcaaa gctttactta aatacttcga acttactgcc ttagcctcat cgatgctgtc
    22141 agattttcta atgatttgga tacattcttc aaattctttg cgttcactat cacgacgtaa
    22201 ctgttcgatt ttcaatttga agtctggatt tttacgcatt tctaataaaa tcggtaacgt
    22261 aatatgacca ttaagcaaat cacttccgac cggcttacct aatttctttt cggtacttgt
    22321 gaagtctaat acatcatcaa tgatttggaa gctcatacct atataatgac caatcatttt
    22381 caattttcgt acagtctctt tatcagattg agaagtaatt gcaccaactt cagttgatat
    22441 ttgaattaac agtgctgttt tgcgattgat acgtcgtaaa taattaataa ttgtctgttg
    22501 actgttaaat tggtcttgaa attggaaaag ttcccctcta caaacatcaa cgatagattc
    22561 agatatcaat tgatgtacac gattatcttt aacggccatt aagtgttcaa gtcctaatgc
    22621 caataaaaaa ttcccagtta aaatagcagt tgtctgatcc catttctttg atatggttaa
    22681 cttgcctcga cgcttgtcgc ttttatcaat aacgtcatca tgaacaagtg ttgccatatg
    22741 aattaactct aatgcgactg caacttgata cgtttgttca gacgtttgtt catctttgcc
    22801 aaattggcta ctcagaataa caaatgctgg gcgtactctt ttaccaccag aagacaataa
    22861 gtgtaatgat gcctgttcta atacagaatc tttacttttt attgcctttt caagtcgttg
    22921 ttccactttc ttaatttcat tgttcatgtt taactttgcc acgttaatca cctttggtat
    22981 tatctttttc tttatagcca aggtgcattg cagcaacgcc ccctgtaaaa ctacgtactc
    23041 ttacatttat gaaacctgct tcttcaaaca tgcgcttcaa ctcttctttt ccaggaaaat
    23101 taaacgtaga ttgctgtaac cattcatatt cttcttttga ttttgcaaat aattttccaa
    23161 aaataggcat aacaaattta aagtatagtg catacatttg tttaaagact ggcaaagttg
    23221 gttggctcgt ttcaagacat accaccatac cacctggttt aagtactcta ttcatttctt
    23281 ttaacgcgac taaatagtct ggcacatttc ttaatccaaa cccaattgtt acataatcaa
    23341 aagaattgtc ttcaaacggc aattccattg catcaccatg aacaagttta acattttcca
    23401 ttgaagcagt tttttctttt cctacttcta acatattctc actaaagtca ataccagtaa
    23461 cttcacctgt tggtcctaca gctttgctta atgcgattgt ccaatcacca gtaccacaac
    23521 aaacatctaa tgctttcgtc ccttttctaa cacccatgtc tttcatgacg cgttttctcc
    23581 atactttatg ctgctcaaaa ctaataatat tatttaatct atcatatttt tttgaaatat
    23641 tttgaaaaac gcgatgtact tgctctttat ttgctttatt gtcagccatg cttaattacc
    23701 tctacttttt aaataacttt tttggatatc gtgtaagtaa tgctttactt cactttgatt
    23761 atatttcttg aagtatgatg gatagtaatc agacatatct tcaaataaat aattatatat
    23821 ttccgactca tcaatattga taccgaaatg agataacgta atatatggga aaagtgtttc
    23881 aatttttact attgcttgag aaatttcata atcatttaaa gcttgatgat gtaatgaaga
    23941 tttcaattca ttaatttcaa caattgcttt actaatttca ttttgaaatg ataaatcatt
    24001 gatttctgct agtagcgtat aaaaatgtgc actaattaaa tctccaatca aaatggaatg
    24061 tttagacaaa tgattatatg taatgtcatc aaggtgtctc attgatgtgt caattgtgag
    24121 gcatgctact ttggcaacat ctggaatatc atatgaatca agtaacttac ctaaccgatg
    24181 attaatatta atggattcat attctgatac accctttaat ctttcttcta tttgtctttc
    24241 caatttgcta acagttgttt ccatgtctac acctcacgat attatcacta ttcatattaa
    24301 cattatatgt aagaaattaa aatcttttga agcattaaga ttacttatca tttttaaatt
    24361 tcaatttaaa ctaacagtaa tttatgtagc ttttgtaatt ctcataataa cctttacttc
    24421 atttacatta ttcatctttt taaataacgt aaaatactat agtagacatg gttacctttt
    24481 aagtaaattc aacgctaaca attaatctca ttattcatat gtatattttg tagttgctat
    24541 ttttatcaaa actattatgt catgtaatat tttgaacgct taaacaatga atgttccaaa
    24601 gattaaaaac ttagaagaac attacaaatt atgtacaggt tgtaagtatt aaaagcaaaa
    24661 taaaaagccc ttattcaggg ctttttaagt aaaattattt tacagcatct tttaatgctt
    24721 taccagcttt gaatgctgga actttacttg ctgggatatc aatttcttta ccagtttgag
    24781 ggttacgacc tttacgtgca gcacgttcac gtacctcaaa gttaccgaaa ccaattaatt
    24841 gtactttttc acctttagca agtgagtttt ggattgattc gaatacagca tctactgctg
    24901 aaccagcttc ttttttagtt aaatcagctt gctctgcaac tgcattgatt aaatctgttt
    24961 tgttcattag acattcacct cctgaggttt gataatgata tgtttatatc attatggtaa
    25021 aactttaaca caagcattac ataaatcgca atcatttatg tggcaaaaac gttgaattta
    25081 agccatttct attcatttta cgtaattatt agccgtatat gtgtaataat acacatttta
    25141 ttcagatttt ttatcgcgct ccattaaatc ttttacgcat tcttttactg agatattttc
    25201 aaataatact ctatataatg catttgtaat tggcatatcc acattttttt ctttagctaa
    25261 atgataaact gatttagttg tataaatacc ttcaacaacc atattcattt cagataatgc
    25321 ttgatccatt gattcacctt gtccaagttt atatcctaat gtgaaatttc gagaatgtgt
    25381 tgatatgcaa gtaacgatta agtcaccgat accacctaaa cctagaaatg tcataggatc
    25441 ggcacctaac ttttcaccta atctactaat ttccgctaaa ccacgagtca ttaacgcagc
    25501 ttttgcatta tcaccgtagc caattccagc tacgatacca cttgctactg cgatgatatt
    25561 tttcaatgca ccaccaagtt caacaccaat caagtcatca ttcgtgtaca cacgcaaata
    25621 atcattcata aataaatctt gcgttaattt acttacactt ttatcttttg atgatgcagc
    25681 aactgtagtt ggttgcttga ctacaacttc ttccgcatga cttggccctg acaacacgcc
    25741 aatacctgca ttatattcgg gtgaaataga atcttcaatc atttctgaca cacgtttaaa
    25801 cgtcccattt tcaatacctt tagcaacatg tataaaagtc tttttagagg tcagcttatc
    25861 attaatttga gtagcaactt ctcgcattgc tttagtaggt aaagccatta agtaaatatc
    25921 tgcaaattga attgctttgg tcatatctga agtagcgatg atgttaacat ctaatttcgc
    25981 gtattttaaa tactttttat ttgtatgaca tgtatttaat tcatcaacag catcttgatt
    26041 tttaccccac atcaaaacat catgtccatt ttctgcaaga acattggcaa gggctgtccc
    26101 aaaacttccc ataccaaaaa cggtaatttt agtcattgtt atcccccaat cgttaatttc
    26161 tctttcgagc tataatatga attggtgtac cttcaaaacc aaaagcggca cggatttgat
    26221 tctctaaata gcgtttataa gaaaaatgca ttaattctac atcattaaca aatacaacaa
    26281 atgtcggtgg ttctatagca acttgtgttg cataaaagac attcaaacgt ctacctttgt
    26341 ctgttggtgt agggttcatg gaaattgcat cagtaacaac ttcatttaaa gttgaacttt
    26401 gaacacgttt tttatggttt tcacttgctt cattaatgta agggaataat gtacgtaatc
    26461 ttgtgcgttc tttagcagac acaaaagcaa tttgtgcata atctaaaaat tggaattctt
    26521 tacgtacttc atcttcaaat ttcttcatcg ttttactatc tttttccaca gtatcccatt
    26581 tatttacgac aatcacgact gctttacctt gttcatgtgc atatcctgca acacgtttat
    26641 cttgttcaat gatgccttgt tctgcatcaa tgaccactaa aacaacattt gaacgttcaa
    26701 tcgcttttaa agctcttagt actgaatatt tctcagttga ttcatatact tttccttttt
    26761 tacgcatacc agcagtatcg attaaaacat aatcttgtcc atcataacta tactctgtat
    26821 caatagcgtc tctcgttgtc cctgcaacat tagaaacgat aacgcgatct tcacctaaaa
    26881 tagcatttac taaacttgat ttacctacgt ttggtcgtcc aataatggat agtcgaattg
    26941 tatcttcatc ataaggatct tcttcctctt caccaaaatg agaaacaact gcatctaaca
    27001 agtcaccaag acctaaacca tgtgaccctg atatcggata cggttcacca aatcctaatg
    27061 aatagaaatc atacacgtct gtacgcattt ccatattatc tactttgtta accgctaata
    27121 cgaccggttt tttagatttg tataaaattt gagcgaccat ttcatcgctt tgtgtcaatc
    27181 cttcacgcac gttaaccata aaaataataa catccgcttc acctatggcg atttctgcct
    27241 gcgctctaat ttgtgtttgg aatggtgcat caccaatttc aataccacct gtatcaataa
    27301 tattgaaatc atgtgttaac cattcacctg aagaataaat acgatctcgt gttacacctg
    27361 gcgtgtcttc cacaatcgaa acacgttctc caactattct attaaaaatt gtagatttac
    27421 ctacattagg cctacctaca atagctacta taggtttagt cataagctaa cttcctctct
    27481 ttcttatatc tttttaataa tatcacatga gactgtgtat tcaaaatgag tttattactg
    27541 taatgataaa aatcagcact taaaacttta tctttttaaa cacttagtta aatttgtcca
    27601 cgttatcatt ccgagtatat tttgttacat aaaaatactc cacatgcaat cataaacatg
    27661 tggagttgac tattaaatat taaattatag tttaagattt ttaagtttat caccaatcat
    27721 atcgccaatt gttggattat cttcttcttc gttttctaag tacgccttag tcgtagaagg
    27781 atcactttca acaacatctt cgtttggtaa tgttgcttta atagatagtg atactctttc
    27841 attctcttca tcaataccta atattttaac atttacttgt tgaccaggtt ctaacacttc
    27901 acctggcgta ccaatgtgtt tgtgtgcaat ttcagaaata tgtacaagtc cttgtacacc
    27961 tggtgcaatt tcaacaaatg caccaaagtt tgccaatctt actacgacac cttcaatgac
    28021 atcattttcg tggaattgac ctttaatatt ttcgaaaggt gttggtaacg tatctttgat
    28081 tgataatgaa atacgttctg tatctctatc aatagattta attttaactt taacatcttg
    28141 accaattgaa actacttctt ctggtgtttg aacatgttcg tgagaaagtt cagatacatg
    28201 cactaaacca tcaacaccac caatgtctat aaatgcacca aattgagtta aacgcgctac
    28261 tttaccatga ataacatcgc cttcatttaa agattgtaat aattgatctt ttttagcatc
    28321 gttttcttct tgttcaactg ctttacggct taaaatgact ctattatttt caggatccaa
    28381 ttcttcaact ttaatacgaa ttgtttgtcc atcaaacaca gagaaatcct caatgaagtc
    28441 tgttgaaatt agtgaagccg gaacaaaacc tctttgtcct acatcaacaa ccaaaccacc
    28501 tttaactact tctgttactt tcgcttcgat gatttcatta ttatctaatt tttcttgtaa
    28561 ataactataa gacttctcag tttcaagttg tcttctagat aagatgtaag ctccagtttc
    28621 attttcttca tcaaactcaa ctttagtgac atatgcttca acttcgtcgc cctcttttac
    28681 aacttcactt gggctatcaa tatgatgcgt agatagttga ctaataggaa taatcccatt
    28741 aaatttacca ccgttgatat gaacaacaac ttgcttgtct tcaacttgtt gtacctcgcc
    28801 agtgactttg tcaccttctt taatatcgtt aatcattgat tcattgaatt cttcagtcat
    28861 cttgtttgcc tccttataca ctacatattt ataacatctt ataaactgac agaattgtca
    28921 agaaattcta cctttattac atttagtaaa ttagttgtat ccataaatat gtcacttaat
    28981 ctcattctgt aaattagttg gacatatatt tattacaacc atatattcaa acaagtaata
    29041 aagtccgcta tgtttataca tattttttgt ataaaaatta gcatagctta ctattttgtt
    29101 ttataagtct gtcatttcat tgttctctac aagatatatt atagtaaaat tttatacttt
    29161 tataaaacaa aaagccacgc aaataagcaa cttttacatt tgaatagtaa gaagaccgta
    29221 tatagtgcat ctttctcgaa ttattacata ggacattttt tgtgactaaa tcaacttctt
    29281 ttgcaatatt tagatttgta acactcattt tcttaccatt tgtaaaatgc tttatgaatg
    29341 taatgaatta tttttggaat tctaataatt cacctttatt atttcttttt actttttgaa
    29401 aaacttacac aattcactga cgcatgaact tttaccaaaa ataaaaaggc aactttcatt
    29461 catcattgaa taaaaatcac cttttaattt gagtaaatca ttatcagcac attcattttg
    29521 tatatgcgtt aagcgttgca cattacaaat agatagttat gacttattag attatttaat
    29581 ttgactcacc atcgctaaaa tttcgtcagt aacttcttca atcgacttgc ctgtcgtatc
    29641 taatgtcact gcatcatctg cttttcttaa tggtgatatt tcacggttca tgtcatattg
    29701 atcacgagct tcaatatcac gttttaaatc ttcaaaattt gattcgatac ctcttaattg
    29761 attatcttta tatcttcttt ctgctcgctc ttcaactgat gcaatcatat atacttttaa
    29821 atctgcatct ggtagcacta cagttccgat atcgcgacca tccattacga tacctttttc
    29881 tgcagctaac tctttttgtt ttttaacggc gaatgaacgt actggctctt tagatgcaac
    29941 gtatgaaaca tgttgcgtca catcattatt tcttaaaaag tctgttacat cttcgttatc
    30001 taaaatgaca cattgacctt tatctgcttt ataagttaaa tctaatgttg tttggtcaac
    30061 tagttttgca aagtcctcag ttttgtttaa ttttaaatat ttgtatgtta atgcacgata
    30121 cattgctcct gtatcgacat aaatcattga tagttcgctg gctacacgtt tcgcaattgt
    30181 actttttccg gcagcagctg gaccatctaa tgcaatatta atggctttca tgcgtcattt
    30241 cccttccttg tcgttttatg aataatattt tatcataatt aggtaaatta aatataggag
    30301 gaaatatatg aaacatctac ttgttattca tactggtggc accattagta tgtcacaaga
    30361 ccaatctaat aaagtagtaa caaatgatat caaccctatt tcaatgcatc aagatgtcat
    30421 aaatcaatat gcacaaatag atgaattaaa tccttttaat gtaccatcac ctcatatgac
    30481 aatccaacat gttaaacaat taaaggatat tattttagaa gcagtaacaa ataaatatta
    30541 tgatggtttc gttatcacgc atggtaccga tacgttagaa gaaactgcct ttttacttga
    30601 tttaatatta ggtatcgagc aacctgttgt tattactggc gcaatgcgct cgtctaatga
    30661 aattggttct gacggattat ataattatat ttccgctatt cgcgttgcct ctgatgaaaa
    30721 ggcccgtcat aaaggcgtga tggttgtatt taatgatgaa attcatacgg cgcgtaatgt
    30781 taccaaaaca catacgtcta atacaaacac atttcaaagt ccaaatcatg gtccgctagg
    30841 tgtattgaca aaggatcgtg tgcaattcca tcatatgcca tatcgccaac aagcattgga
    30901 aaatgtcaat gacaaactaa atgtaccatt agtaaaagca tatatgggta tgccaggtga
    30961 catttttagt ttttatagtc gtgaaggtat cgatggtatg gttattgaag cgttaggaca
    31021 aggcaacata cctccaagcg cattagaagg cattcaacaa ttagtatctt taaatatacc
    31081 tattgtgcta gtttcacgtt cctttaatgg tattgtgagt ccaacttacg catacgatgg
    31141 tggtggttac caactcgcac aacaaggttt tattttttct aacggttcga atggtccaaa
    31201 agcaagatta aaattattag ttgcgttaag caacaattta gataaagctg aaatcaaatc
    31261 atattttgaa ttataatgaa tacgtaacat aaaaaggtct atgtacaata attagtcatc
    31321 aacctcattt gacatatcat gaatgtcagt cgttgtaaaa ctaagttatt tagtacatag
    31381 acctttattt ttatgattct aacggcgttt gtttcttagc tagcatgttt tgagcaataa
    31441 tgccaccgtg gaatttacca ttttcaataa aaatggtatt cgcatcgttc cctgcagcaa
    31501 ttacacctgc aatatagcaa ttttcgatat ttgtttcgta tgtttcttta ttatacatag
    31561 gcgctgttcc aaattcattt gtattaattt gaatgcctac agattttaaa aattcataat
    31621 cgggatgata accaatcatc gcaaatacat aatcattgtg tattgtttta ctttcaccat
    31681 ttacttcata agtcacagta tcttcagtta tttgggtaac attagcatta aattccatgt
    31741 caattttttc atgatttact aatgctgtga aatttggaag tatccacggt ttaattgaag
    31801 gcgaataatc tccaccacga tatagaaccg tcacgttagc accagctttt tccaactcca
    31861 aagcagcatc gatagccgaa ttcttaccac caataataac aacatcttga tcaaaatacg
    31921 gatgtgcctc tttaaaataa tggaacactt taggtaaatc cgctccttca acttctaatg
    31981 tattatgctg accataatag cctgtcgcga ttgttaaaaa tcgacattca taaacatctt
    32041 tcgtcgtagt aatagtaaat ttattattca tttttttaac agttaatact tcttcaaatg
    32101 catttacttt taattgatga tgttttacaa cttctcggta ataaactagc gcttgattac
    32161 gtcttggttt actttcttca acgataaacg gtacgtcccc aatacttaat ttatcacttg
    32221 atgagaaaaa tgtttggtga gtaggataat tatagattga ttcaacgaca ttcccctttt
    32281 caataattaa ggtatcaata ccttttcttt tttgttcaat agccgcactt aatccgcatg
    32341 gccctccacc aattatgata ctttcaactt tttgcattgt ttcggcctcc tttaatccca
    32401 aactattata acagttcagt gattgatgcg ctaagtctgt gcttgaagat ttatgatata
    32461 tttttgacaa tttgtttaat gtgcatagag aattgttagc tacggagttg aataacacta
    32521 caatttaata tgttgattta ttttttattc tccctcgtta aatttgttga ttgtggtgtt
    32581 ttatcttttt gatgactatt taaaaagttt aattgatatg cc
//
LOCUS       DAPDIM010000029        32610 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000029 DAPDIM010000000
VERSION     DAPDIM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 32610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32610
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.029"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..219)
                     /locus_tag="RFE25_001406"
     CDS             complement(<1..219)
                     /locus_tag="RFE25_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDU2816475.1"
                     /translation="MEKQLQIRKQSAFTMIEMLVVMMLISIFLLLTMTSKGLSNLRVI
                     DDEANIISFITELNYIKSQAIANQGYINV"
     gene            complement(197..508)
                     /locus_tag="RFE25_001407"
     CDS             complement(197..508)
                     /locus_tag="RFE25_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDU2816476.1"
                     /translation="MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQST
                     GCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFIKEAQKTCKSGETITISNGEAVA
                     N"
     gene            complement(522..1592)
                     /locus_tag="RFE25_001408"
     CDS             complement(522..1592)
                     /locus_tag="RFE25_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDU2816477.1"
                     /translation="MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSF
                     QFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIGYSDTIVMQVYLAERFGNIIDVL
                     EETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
                     SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQ
                     LFKTYFVTNELVLFYKNGITLQSIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQIL
                     EKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIKQTQFLQPILFLILG
                     LFIVAIYLVIMLPMFQMMQSIK"
     gene            complement(1564..2538)
                     /locus_tag="RFE25_001409"
     CDS             complement(1564..2538)
                     /locus_tag="RFE25_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDU2816478.1"
                     /translation="MKILFQEIINKAIEMKANDVHFIPVKNEVSIKFRINDNLEQYEQ
                     IGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHFNKIYFLRISTLPLSLGQESCVI
                     RIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
                     VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVI
                     QASLSGHLVLTTLHATDCKGAILRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLV
                     CEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTMDKYI"
     gene            complement(2590..3213)
                     /locus_tag="RFE25_001410"
     CDS             complement(2590..3213)
                     /locus_tag="RFE25_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDU2816479.1"
                     /translation="MRISSLTLGLVDTNTYFIENDKAVILIDPSGESEKIIKKLNQIN
                     KPLKAILLTHAHFDHIGAVDDIVDRFDVPVYMHEAEFDFLKDPVKNGADKFKQYGLPI
                     ITSKVTPEKLNEGSTEIEGFKFNVLHTPGHSPGSLTYVFDEFAVVGDTLFNNGIGRTD
                     LYKGDYETLVDSIQDKIFELEGDLPLFPGHGPYTTVDDEQLNPFLHG"
     gene            complement(3210..3539)
                     /locus_tag="RFE25_001411"
     CDS             complement(3210..3539)
                     /locus_tag="RFE25_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDU2816480.1"
                     /translation="MAIVDVVVIPVGTEGPSVSKYIADIQKKLQEYKAMGKIDFQLTP
                     MNTLIEGELSDVLEVVQVIHELPFDKGLSRVCTNIRIDDRRDKSRKMNDKLTSVQKHL
                     ENSGENL"
     gene            complement(3539..4525)
                     /locus_tag="RFE25_001412"
     CDS             complement(3539..4525)
                     /locus_tag="RFE25_001412"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HDU2816481.1"
                     /translation="MTKIILAADVGGTTCKLGIFTPELEQLHKWSIHTDTSDSTGYTL
                     LKGIYDSFVEKVNENNYNFSNVLGVGIGVPGPVDFEKGTVNGAVNLYWPEKVNVREIF
                     EQFVDCPVYVDNDANIAALGEKHKGAGEGADDVVAITLGTGLGGGIISNGEIVHGHNG
                     SGAEIGHFRADCDQRFKCNCGRSGCIETVASATGVVNLINFYYPKLTFRSSILELIKE
                     NKVTAKAVFDAAKAGDQFCIFITEKVANYIGYLCSIISVTSNPKYIVLGGGMSTAGPI
                     LIENIKTEYHNLTFAPAQFETEIVQAKLGNDAGITGAAGLIKTYVLDKEGVK"
     gene            complement(4522..4725)
                     /locus_tag="RFE25_001413"
     CDS             complement(4522..4725)
                     /locus_tag="RFE25_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HDU2816482.1"
                     /translation="MSRKINNFYDVQQLLKSYGFLIYFKNPEDMYEMIQQEISSLYQY
                     ELLSKEEYLKCTLIINQRRNEQK"
     gene            complement(4706..6169)
                     /locus_tag="RFE25_001414"
     CDS             complement(4706..6169)
                     /locus_tag="RFE25_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001652331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDU2816483.1"
                     /translation="MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVI
                     FKQHIKSTQEIRFDKAKVLEHKDEIANFISFEPQSFEFYYFTESEFSEEQLNEVSPIR
                     IKFNVIRHTKDLIKHMPNIFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPAT
                     YTIIFVNVLIWLCMILYLNNFSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHI
                     LMNMLSLFIFGKIVEAIIGSWRMLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLI
                     GSIFAMMYVSKTFNKKMLGQLLIALVILVGVSLFMSNINIVAHIGGFIGGLLITLIGY
                     YYKVNRNIFWILLIGMLVIFIALQIRIFTIKEDNIYNKLIKDDMTSGNYDNAQNIVKQ
                     TINKNYADDQTYYLSGMIMATINSKSEGMTEWERGLRMFPKSGLLNFELAIANRSLND
                     DEKALKYVRKALNADPKNTDYINLEKELTKSNESKNK"
     gene            complement(6181..6720)
                     /locus_tag="RFE25_001415"
     CDS             complement(6181..6720)
                     /locus_tag="RFE25_001415"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDU2816484.1"
                     /translation="MTKNEIRKYILHKMKNFNKAEKRKADTWLRNQFFATEEYKEANA
                     IALVLSFNHEVDTFSIIEQALMDHKRIFVPKMDYLNHQMTFKEIFNLKDIDVDNKGIY
                     YPTSKGETTNNLDLIVVPGVGFQDDGYRIGYGGGYYDRFLANYQTKTISLLYDFQITS
                     FEPESFDQPVDKLIIYQSA"
     gene            complement(6929..7078)
                     /gene="rpmG"
                     /locus_tag="RFE25_001416"
     CDS             complement(6929..7078)
                     /gene="rpmG"
                     /locus_tag="RFE25_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDU2816485.1"
                     /translation="MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTL
                     HRETK"
     gene            complement(7191..9266)
                     /locus_tag="RFE25_001417"
     CDS             complement(7191..9266)
                     /locus_tag="RFE25_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDU2816486.1"
                     /translation="MLKRLKEKSNDEIVQNTINKRINFIFGVIVFIFAVLVLRLGYLQ
                     IAQGSHYKQIIKNDENITVNESVPRGRILDRNGKVLVDNASKMAITYTRGRKTTQSEM
                     LDTAEKLSKLIKMDTKKITERDKKDFWIQLHPKKAKAMMTKEQAMLADGSIKQDQYDK
                     QLLSKIGKSQLDELSSKDLQVLAIFREMNAGTVLDPQMIKNEDVSEKEYAAVSQQLSK
                     LPGVNTSMDWDRKYPYGDTLRGIFGDVSTPAEGIPKELTEHYLSKGYSRNDRVGKSYL
                     EYQYEDVLRGKKKEMKYTTDKSGKVTSSEVLNPGARGQDLKLTIDIDLQKEVEALLDK
                     QIKKLRSQGAKDMDNAMMVVQNPKNGDILALAGKQINKSGKMTDYDIGTFTSQFAVGS
                     SVKGGTLLAGYQNKAIKVGETMVDEPLHFQGGLTKRSYFNKNGHVSINDKQALMHSSN
                     VYMFKTALKLAGDPYYSGMALPSDISSPAQKLRRGLNQVGLGVKTGIDLPNETRGQIE
                     PLTNNPGNYLDLSIGQYDTYTPLQLSQYVSTIANDGYRIQPHIGLTIHESTNKDEVGP
                     LKKKINGTVLNKVNNTEKEIKQIQEGFKMAFNDKDGTGYVSFKDTVVPTAGKTGTAEV
                     FQNGEPRVNSTYIGYAPIDDPKLAFSIVYTNQPVPPPWLTGGDLGRDVINYYFKQLGK
                     DDKNKDKDK"
     gene            complement(9387..9986)
                     /locus_tag="RFE25_001418"
     CDS             complement(9387..9986)
                     /locus_tag="RFE25_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDU2816487.1"
                     /translation="MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVE
                     GTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKI
                     KEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGL
                     DVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK"
     gene            complement(10262..10672)
                     /locus_tag="RFE25_001419"
     CDS             complement(10262..10672)
                     /locus_tag="RFE25_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDU2816488.1"
                     /translation="MNTNDAIKILKENGLKYTDKRKDMLDIFVEEDKYINAKYIQQVM
                     DENYPGISFDTIYRNLHLFKDLGIIENTELDGEMKFRIACTNHHHHHFICEKCGDTKV
                     IDYCPIDQIKLSLPGVNIHKHKLEVYGVCESCQD"
     gene            complement(10659..11522)
                     /locus_tag="RFE25_001420"
     CDS             complement(10659..11522)
                     /locus_tag="RFE25_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDU2816489.1"
                     /translation="MIDALLNFDFMRYSLISGILIGFIAPLIGAFIVVRRLSLIADAL
                     SHVTLGGISFGMFLLTIMPTLVFINPMWFGILFAIVGALLIEKLRTSYTAYQEIAIPI
                     IMSAGIALSAIFISLADGFNQEIVGLLFGSISAVNISDLTTIIVIAIIVVLFITLFYK
                     ELFILSFDEEYSKVIGIHKWIQFLFIVIVAMVISASMRVVGILLVSALITLPIAISMR
                     ITKSFKQLILLSVFLGELSVILGLVLAFYMDISPGGVIVVLLVILLMITMAYQKMRMK
                     FKKGANINEYK"
     gene            complement(11564..12349)
                     /locus_tag="RFE25_001421"
     CDS             complement(11564..12349)
                     /locus_tag="RFE25_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDU2816490.1"
                     /translation="MRGENTMTPVFELKNVNYYYDHKKVLENINIKINKGEFLAIVGP
                     NGAGKSTLLKLILGLLPLQSGEIFVEGIDFKNKKTSIKLSYVSQKANAFNSGFPASVK
                     EVVLSGLTKTKRLFQTFNSKDNEKVIKVLERLNISDLIHKNIAELSGGQQQRVMIARA
                     LISEPAVLVLDEPTNGIDAKHVSEFYNTLDQLKQEGITIILVTHDIGVVADTATEVAC
                     LNKHLHFHGTTDEFKSLDEVEISKIYGHPVRFVDHQHNRECCN"
     gene            complement(12475..13365)
                     /locus_tag="RFE25_001422"
     CDS             complement(12475..13365)
                     /locus_tag="RFE25_001422"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDU2816491.1"
                     /translation="MLLGSHVSMSGKKMLEGSAIEAYEYGETTFMIYTGAPQNTRRKS
                     IEDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIG
                     AKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEEL
                     ARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSK
                     NDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLE
                     IEMLKQQQFDPELKNKVMQQ"
     gene            complement(13375..14721)
                     /locus_tag="RFE25_001423"
     CDS             complement(13375..14721)
                     /locus_tag="RFE25_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDU2816492.1"
                     /translation="MAKHPFEQFNLESSLIDAVKDLNFEKPTEIQNRIIPRILKRTNL
                     IGQSQTGTGKSHAFLLPLMQLIDSEIKEPQAIVVAPTRELAQQLYDAANHLSQFKAGV
                     SVKVFIGGTDIEKDRQRCNAQPQLIIGTPTRINDLAKTGHLHVHLASYLVIDEADLMI
                     DLGLIEDVDYIAARLEDNANIAVFSATIPQQLQPFLNKYLSHPEYVAVDSKKQNKKNI
                     EFFLIPTKGAAKVEKTLNLIDILNPYLCIIFCNSRDNANDLARSLNEAGIKVGMIHGG
                     LTPRERKQQMKRIRNLEFQYVIASDLASRGIDIEGVSHVINFDVPNDIDFFTHRVGRT
                     GRGNYKGVAITLYSPDEEHNISLIEDRGFVFNTVDIKDGELKEVKAHNQRQARMRKDD
                     HLTNQVKNKVRSKIKNKVKPGYKKKFKQEVEKMKRQERKQFSKQQNRQKRKQNKKG"
     gene            complement(14835..15935)
                     /locus_tag="RFE25_001424"
     CDS             complement(14835..15935)
                     /locus_tag="RFE25_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDU2816493.1"
                     /translation="MKIADLMTLLDHHVPFSTAESWDNVGLLIGDGDVEVTGVLTALD
                     CTLEVVNEAIEKGYNTIISHHPLIFKGVTSLKANGYGLIIRKLIQHDINLIAMHTNLD
                     VNPYGVNMMLAKAMGLKNISIINNQQDVYYKVQTYIPKDNVGPFKDKLSENGLAQEGN
                     YEYCFFESEGRGQFKPVGEANPTIGQIDKIEDVDEVKIEFMIDAYQKSRAEQLIKQYH
                     PYETPVFDFIEIKQTSLYGLGVMAEVDNQMTLEDFAADIKSKLNIPSVRFVGESNQKI
                     KRIAIIGGSGIGYEYQAVQQGADVFVTGDIKHHDALDAKIHGVNLIDINHYSEYVMKE
                     GLKTLLMNWFNIEKINIDVEASTINTDPFQYI"
     gene            complement(15938..16615)
                     /locus_tag="RFE25_001425"
     CDS             complement(15938..16615)
                     /locus_tag="RFE25_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HDU2816494.1"
                     /translation="MISLNNRLTTVSRFLKQGTIADIGSDHAYLPIYAIQNHLCECGI
                     AGEVIQGPFQAAVKNVAANHLVERIDVRLGDGLSVIHPEDVIDNITICGMGGPLIAKI
                     LKDGQDKLSQHPRLILQSNIQTENLRQTLQQLNYEIIDEIIMEEKGHIYEIVVAEHST
                     QLIELSSDELKFGPKLLNNKNEYFIKKWQRELEALYHIKSKLNTEQHHQRLAQINDEI
                     AVIERVL"
     gene            complement(16746..17852)
                     /gene="rpoD"
                     /locus_tag="RFE25_001426"
     CDS             complement(16746..17852)
                     /gene="rpoD"
                     /locus_tag="RFE25_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDU2816495.1"
                     /translation="MSDNTVKIKKQTIDPTLTLEDVKKQLIEKGKKEGHLSHEEIAEK
                     LQNFDIDSDQMDDFFDQLNDNDISLVNEKDSSDTDEKLNPSDLSAPPGVKINDPVRMY
                     LKEIGRVNLLSAQEEIELAKRIEQGDEVAKSRLAEANLRLVVSIAKRYVGRGMLFLDL
                     IQEGNMGLIKAVEKFDFNKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LIRVQRQLLQDLGRDPAPEEIGEEMDLPAEKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDQEAQSPSDHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGK
                     VFGVTRERIRQIEAKALRKLRHPSRSKRLKDFMD"
     gene            complement(18076..19893)
                     /locus_tag="RFE25_001427"
     CDS             complement(18076..19893)
                     /locus_tag="RFE25_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDU2816496.1"
                     /translation="MRIDQSIINEIKDKTDILDLVSEYVKLEKRGRNYIGLCPFHDEK
                     TPSFTVSEDKQICHCFGCKKGGNVFQFTQEIKDISFVEAVKELGDRVNVAVDIEATQS
                     NSNVQIASDDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGF
                     APDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVG
                     YSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDT
                     AGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVF
                     VIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKE
                     LSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEIQFNQAPANYYPEDEYGGYDEYG
                     GYIEPEPIGMAQFDNLSRQEKAERAFLKHLMRDKDTFLNYYESVDKDNFTNQHFKYVF
                     EVLHDFYAENDQYNISDAVQYVNSNELRETLISLEQYNLNDEPYENEIDDYVNVINEK
                     GQETIESLNHKLREATRIGDVELQKYYLQQIVAKNKERM"
     gene            complement(19954..20772)
                     /locus_tag="RFE25_001428"
     CDS             complement(19954..20772)
                     /locus_tag="RFE25_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDU2816497.1"
                     /translation="MEKIKIIVASDSIGETAELVARAGISQFNPKQCKNELLRYPYIE
                     SFEDVDEVIQVAKDTNAIIVYTLIKPEMKQYMSEKVAEFQLKSVDIMGPLMDLLSASV
                     EEKPYNEPGIVHRLDDAYFKKIDAIEFAVKYDDGKDPKGLPKADIVLLGISRTSKTPL
                     SQYLAHKSYKVMNVPIVPEVTPPDGLYDIDPKKCIALKISEEKLNRIRKERLKQLGLG
                     DTARYATEARIQEELNYFEEIVSEIGCPVIDVSQKAIEETANDIIHYIEQNKSK"
     gene            complement(20783..21406)
                     /locus_tag="RFE25_001429"
     CDS             complement(20783..21406)
                     /locus_tag="RFE25_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001797828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2816498.1"
                     /translation="MELSQRQERIIEIVKTKGPITGEQIADKLNLTRATLRPDLAILT
                     MSGFLEARPRVGYYYSGKSKGKFFNEKLRQFEVKDYMSQPVVLRENTTVYDAICTIFL
                     EDVSTLFIINEDNDFVGVCSRKDLLRASMIGADIHTVPISVNMTRMPNVTYLEESELV
                     IYAADRMIEKEIDSIPIVRKKDNQKYEVIGRISKTTIAKLLVALYKE"
     gene            21741..23132
                     /locus_tag="RFE25_001430"
     CDS             21741..23132
                     /locus_tag="RFE25_001430"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase"
                     /protein_id="HDU2816499.1"
                     /translation="MAKDMDTIVSLAKHRGFVFPGSDIYGGLSNTWDYGPLGVELKNN
                     VKKAWWQKFITQSPFNVGIDAAILMNPKVWEASGHLNNFNDPMIDNKDSKIRYRADKL
                     IEDYMQDVKGDENFIADGLSFEQMKKIIDDEGIVCPVSKTANWTEIRQFNLMFKTFQG
                     VTEDSTNEIFLRPETAQGIFVNYKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFIFRT
                     REFEQMELEFFCKPGEEIEWQNYWKTFASDWLTSLNMSSENMRLRDHDEDELSHYSNA
                     TTDIEYKFPFGWGELWGIASRTDFDLRKHAEHSGEDFRYHDPETNEKYIPYCIEPSLG
                     ADRVTLAFLCDAYDEEGVEGSKDARTVLHFHPALAPYKAAILPLSKKLSGEAIKIFEQ
                     LSSKFSIDFDESQSIGKRYRRQDEIGTPYCVTFDFDSLEDNQVTVRDRDSMEQVRMPI
                     SELEAFLTEKTKF"
     gene            complement(23282..24028)
                     /gene="recO"
                     /locus_tag="RFE25_001431"
     CDS             complement(23282..24028)
                     /gene="recO"
                     /locus_tag="RFE25_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDU2816500.1"
                     /translation="MRQKGIIIKAVDYGESDKIITILNEHGAKVPLMARRAKKVKTGL
                     QAQTQLFVYGLFIYNQWRGMGTLNSVDVISQHYKLQMDLYVSSYASLAAETIERSMDE
                     GDIAPYNYQLLQFVLEKIESGTSAQLMSVVVMLKCMKRFGFTASFNRCAVSGNDTQAD
                     LIGYSFKFDGAISRQEASKDVHAVILSNKTLYLLDVLQKLPIDKMNSLNIHQEIIDEM
                     SDIILMLYREYAGMFFKSQKLINQLKRLEQ"
     gene            complement(24056..24955)
                     /gene="era"
                     /locus_tag="RFE25_001432"
     CDS             complement(24056..24955)
                     /gene="era"
                     /locus_tag="RFE25_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDU2816501.1"
                     /translation="MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNK
                     IQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRG
                     DEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVD
                     HFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRM
                     VKESEDRVHIEATIYVERDSQKGIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWV
                     KVQRDWRNKVNFIRQIGYVEDQD"
     gene            complement(24956..25360)
                     /gene="cdd"
                     /locus_tag="RFE25_001433"
     CDS             complement(24956..25360)
                     /gene="cdd"
                     /locus_tag="RFE25_001433"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDU2816502.1"
                     /translation="MSYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNV
                     ENASYPLSICAERASLVSAISQGYRPGDFESITVTVDADKPSSPCGACRQVLKELCDD
                     DMPVYMTNHKGDMVMMTVAELLPFGFSGKDLE"
     gene            complement(25371..25715)
                     /locus_tag="RFE25_001434"
     CDS             complement(25371..25715)
                     /locus_tag="RFE25_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDU2816503.1"
                     /translation="MKRFKYALDGLKILIQKDYKFLLHVFAMIVAIVFGLVLNINRIE
                     WIFILIAIALVLTVEALNTAIEYVVDLVTVEYHDLAKYAKDIAAFSVLIVSILAFIIG
                     LIVFLPHFIALF"
     gene            complement(25718..26185)
                     /gene="ybeY"
                     /locus_tag="RFE25_001435"
     CDS             complement(25718..26185)
                     /gene="ybeY"
                     /locus_tag="RFE25_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDU2816504.1"
                     /translation="MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTF
                     VDKQEIQEINRTYRDKDKVTDVISFALEEDEPEIDFSGLDIPRVLGDIIICTDVAQEQ
                     ANNYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD"
     gene            complement(26186..27133)
                     /locus_tag="RFE25_001436"
     CDS             complement(26186..27133)
                     /locus_tag="RFE25_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDU2816505.1"
                     /translation="MPGIIQIDDMNQSQALIGNNDEHLKAIEESFDVVIHARGQEVAV
                     KGTKIENVEKAESVLINLLKVIDLGNNITIKDVEAAIKMAHNNTIQHLLDLYDEEITK
                     DAFGKTIRAKTMGQRIYVNAMKNNDLVFGIGPAGTGKTFLAVVYAAKQLRKGAVKRIV
                     LTRPAVEAGESLGFLPGDLKEKVDPYLRPLYDGLYTVLGREQTERFIERGIIEIAPLA
                     YMRGRTLEDAFVILDEAQNTTHAQMKMFLTRLGFGSKMVVTGDQTQIDLPKGVKSGLK
                     EAVSRLHNVKGISILKLDQSDVVRHPLVSKIIEHYEGEN"
     gene            complement(27437..28135)
                     /locus_tag="RFE25_001437"
     CDS             complement(27437..28135)
                     /locus_tag="RFE25_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron transporter"
                     /protein_id="HDU2816506.1"
                     /translation="MSVGILIFVISVIISIITTMRENSHKDRQNQKPPQKTSTDNEPK
                     KGGFFEEIERTFKEISEELNEEEKKSSKRKYDDTLPPLFDELPKEEPKSKPVVEPMAP
                     KKQPETKPMTEKPITVPKAEPVEQKHRPSRQDNSDEIRRQLEKSLRDDIKTIRTDIDR
                     EKEKQIAKMEKRARDIIEDKYLSERTKRLKLKQLLNSQNVEKDLTKSAFQFDKDEVIN
                     GMIWSEILAKPKQL"
     gene            complement(28152..29141)
                     /gene="floA"
                     /locus_tag="RFE25_001438"
     CDS             complement(28152..29141)
                     /gene="floA"
                     /locus_tag="RFE25_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500186.1"
                     /note="flotillin-like protein involved in membrane lipid
                     rafts; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin-like protein FloA"
                     /protein_id="HDU2816507.1"
                     /translation="MFSLSFIVIAVIIIVALLILFSFVPIGLWISALAAGVHVGIGTL
                     VGMRLRRVSPRKVIAPLIKAHKAGLALTTNQLESHYLAGGNVDRVVDANIAAQRADID
                     LPFERAAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIAR
                     LVGGAGEETIIARVGEGIVSTIGSSKHHTEVLENPDNISKTVLSKGLDSGTAFEILSI
                     DIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVATEQEMKARVQEMHAKVVE
                     AESEVPLAMAEALRSGNISVKDYYNLKNIEADTGMRNAINKRTDQSDDESPEH"
     gene            complement(29159..29842)
                     /locus_tag="RFE25_001439"
     CDS             complement(29159..29842)
                     /locus_tag="RFE25_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HDU2816508.1"
                     /translation="MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYS
                     KKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGM
                     ILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSE
                     SGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEG
                     TRVVVREVD"
     gene            complement(30086..30262)
                     /locus_tag="RFE25_001440"
     CDS             complement(30086..30262)
                     /locus_tag="RFE25_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016998564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDU2816509.1"
                     /translation="MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVK
                     RKKKSEAARKRKFK"
     gene            complement(30555..31901)
                     /gene="mtaB"
                     /locus_tag="RFE25_001441"
     CDS             complement(30555..31901)
                     /gene="mtaB"
                     /locus_tag="RFE25_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDU2816510.1"
                     /translation="MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVI
                     NTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDR
                     HKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFC
                     IIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDL
                     ETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTM
                     DRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPR
                     IGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTL
                     VGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV"
     gene            complement(31908..32609)
                     /locus_tag="RFE25_001442"
     CDS             complement(31908..32609)
                     /locus_tag="RFE25_001442"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002493561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDU2816511.1"
                     /translation="MTKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKI
                     AVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLN
                     EAKVVKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAK
                     DGKLSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAP
                     LYALSAISYEKELMG"
BASE COUNT        10249 a         6000 c         4360 g        12001 t
ORIGIN      
        1 aacattgata tatccttgat ttgctatagc ttgcgactta atataattca attcagtaat
       61 aaaagaaatg atatttgcct catcatctat tactctaaga ttgcttaatc ctttagatgt
      121 cattgtcaaa agtagaaata tactgattaa catcattacc acaagcatct caatcatagt
      181 aaatgctgac tgctttctaa tttgcaactg cttctccatt actaattgtt attgtctctc
      241 ctgatttaca tgtcttttgt gcttctttta taaaaccatc tgcaattaag tcttcaatag
      301 acgatggatt tctattatgt ttcaatgcat acgcttcaat ttgactatta accattttta
      361 cctgtgcatt acaacctgtt gattgtatgt gagcagtttg tttagcaata tttggaatga
      421 ttaaaattaa taataaactg atgattaata acactaatag catctctatc aatgtaaacg
      481 cttgagtttt cttaagaaat ttaaacatat attaacctcc attattttat actttgcatc
      541 atttgaaaca ttggtaacat aattactaaa taaattgcga caataaataa acctaaaatc
      601 aaaaataaaa taggctgtaa aaactgagtc tgttttatcg ctttatcttc tatttgtttt
      661 actaatattt gcgaatataa ctttagttct acttctagct tccctctctt ttcaccttgt
      721 agcacaaact taattaattg aggcttaaag cattttagtt tttctaaaat ttgaggcaaa
      781 ccatatccca tttctgaata agttaataag tatttaccta gaaactgtct aaatggatca
      841 ctactatggt taatataaac gtctactatt gattgaagtg taataccatt tttataaaac
      901 aacactaatt cattagttac aaaataagtt ttaaataatt ggaaatagcc tgatattagc
      961 ggtagtttca tcacaaagtt tatcttattg agcatattta aattgttata aattaatttc
     1021 ataataatag ccaacataga tactattatg agcattacta caattatagt aggtaagctg
     1081 gtaatgaaaa aagacaatgt tttttgaaaa gaagatagtt gaatattcat agaagtatat
     1141 aattgttgaa actgtggaat tactgtgagg tttaatataa taatcatagc aataaagata
     1201 gaaactagta ttaaggggta ttgcagtgtc tttaacaatc gttgttctga ctttctattc
     1261 actttcatat aatttacggt ttcttctaga acgtctataa tattgccaaa tctttctgcc
     1321 aaatatactt gcatgacgat agtatcgcta taacctatca gtgataatat ttgattgcat
     1381 ggtgcaccat ttgaaatttc acttagaatg gtggtaccta attgcttatt tttatatgtc
     1441 atttgaagat ttaaaaattg aaaactttga tacagagtga aaccatattt caacaaatta
     1501 cataaatttg aaagtaaatc gatttgttgg gccttactta attgtcgctt cttagaatgt
     1561 agtttaaatg tatttatcca ttgtagtttc acaaatgaca cctgcttttg tcatatcatc
     1621 aagtttatct tctaagttct taaatgatga tggtaatgaa tgattatggg aaaagaaata
     1681 tcggagttgt tgctgagata gaatttcgca tactaattgt cgctgttgct taatagtagt
     1741 tacaagtcgt tggtttataa ttaagttagt tgcctgtatc aattcttgta cagaaatgcc
     1801 catttctaat agccttaaaa tagcaccttt acaatcagtt gcatgcaatg tagtcagaac
     1861 aaggtgacca cttaaactag cctgtataac acacttggca acatctttat ctctgatttc
     1921 acctattaaa ataacatcag gatcacatct taaaatagct ttaaacgaat ttacatagtt
     1981 aatgccagct ttatcattca cattaatttg gacgatacca ggaatttgca tctctacagg
     2041 atcctctata gaaattacat ttaaattcaa ggctttattc gcgtatgaga ccatttgata
     2101 cattaatgta ctctttcctg aaccagttgg cccactaaac aatagtaatc cttgtttctt
     2161 attcatgagg tgtttaaaat cattgaattt ataagttgat ttctgttgtt gaaaaaattg
     2221 aggtacaatt ctgataacac aactttcttg gccaagtgac aatggtaaag ttgatattct
     2281 caaaaaatat attttattga aatggtaact atatcgaccg ctctgtgcga cttgctgtgt
     2341 agaaacatca agcccagctt gaaacttcat ataaactaat aacttttgat aaatgctatt
     2401 cccaatttgt tcatactgct ccaagttatc attaattcta aatttaatac ttacttcatt
     2461 tttaactgga ataaaatgta catcattcgc tttcatttct atcgctttat taattatttc
     2521 ttgaaataga atcttcaaaa aaacacctcc tacatataat cacgtaggag gtgtttttat
     2581 tacttcaatt taaccgtgta aaaatggatt taattgttca tcatcaaccg tcgtatatgg
     2641 accatgtcca gggaataaag gtaaatcgcc ttctaattca aatattttat cttgaataga
     2701 atcaactagc gtttcataat cacctttata taaatctgta cgtccgattc cattattaaa
     2761 taatgtatct ccaacaactg cgaattcatc gaacacatat gttaaacttc ctggtgaatg
     2821 tccaggtgtg tgtaacacat taaacttaaa tccttctatt tctgtgctac cttcgtttaa
     2881 cttttcagga gttaccttac ttgtaataat tggtaatcca tattgcttaa atttatctgc
     2941 tccattttta acgggatctt ttagaaaatc aaactctgct tcatgcatat aaaccgggac
     3001 atcgaatcga tcaactatat catcgactgc tccgatatga tcaaagtgtg catgtgttaa
     3061 taaaatagct tttaacggtt tatttatttg gtttaatttt ttaataattt tttcactttc
     3121 acctgaaggg tcaatcagaa taacagcttt gtcattttcg atgaaatacg tattagtatc
     3181 aactaagcct aaagttaagc ttgaaatcct cataggtttt caccactatt ttctaaatgt
     3241 ttttgtactg atgttagttt atcattcatt tttctagatt tgtctcgtcg gtcatcaata
     3301 cggatatttg tacaaactct acttaaacct ttatcaaaag gtaattcatg tatcacttgc
     3361 acaacttcta atacatcgct taattcacct tcaattagag tattcattgg tgttaattga
     3421 aaatcaattt tacccattgc tttatattct tgaagttttt tctgaatatc tgcaatatat
     3481 ttactaacac tcggaccttc cgttccaact ggaataacaa ccacatcaac aatagccatt
     3541 attttacccc ctctttatct aatacatagg tcttgattaa tcctgctgct cctgtaatac
     3601 ctgcatcatt acctaatttc gcttgtacaa tttcagtttc aaattgagca ggtgcaaatg
     3661 ttaaattatg atattctgtt ttaatatttt caattaaaat aggtcctgca gtagacattc
     3721 ctccacctag aacgatatat ttcggattac ttgtaacact aataatacta cataaatatc
     3781 caatatagtt tgcaaccttt tcagtaatga aaatacagaa ttggtcacca gcttttgccg
     3841 catcaaaaac agcttttgct gtaaccttat tttctttaat caattctaat atagaagatc
     3901 taaacgtcaa cttcggatag tagaagttaa ttaagttaac aacgcctgtc gctgaagcaa
     3961 ctgtttcaat acatccagaa cgaccacaat tacatttaaa tcgttgatcg cagtctgctc
     4021 taaaatgacc tatttctgcg ccagagccat tatgaccatg tacgatttca ccatttgaaa
     4081 taattcctcc acctagacct gtaccaagtg tgatggcaac aacatcatcg gcaccttcac
     4141 cagcaccttt gtgtttctcc cctaaagcag ctatgttagc atcattatct acatacactg
     4201 gacaatcaac gaattgttca aaaatctcac gtacattaac tttttctggc caatataagt
     4261 ttactgctcc atttactgta cctttttcaa agtcaacagg acctggtaca ccaataccta
     4321 cgccaagtac atttgaaaaa ttataattat tttcatttac tttttcaaca aacgaatcat
     4381 aaattccttt caaaagtgta tatcctgtac tatcagatgt atcagtgtga atagaccatt
     4441 tatgtaattg ttctaattca ggtgtgaaaa tacctaattt acaagtcgtc ccgcctacat
     4501 cagctgctaa aataattttt gtcatttctg ttcattcctt ctctgattaa ttatcaacgt
     4561 acatttcaaa tattcttcct tagataacag ttcatattga tacaatgatg aaatctcctg
     4621 ttgaatcatt tcgtacatat cttctggatt tttaaaatat attagaaatc cgtaactttt
     4681 caataactgt tgtacatcat aaaagttatt tatttttcga ctcatttgat ttagtcaact
     4741 ctttttctaa gttaatataa tctgtatttt tagggtctgc atttaatgct ttacgcacat
     4801 attttaatgc tttttcatca tcatttaatg aacgatttgc tatcgctaac tcaaaattta
     4861 ataaacctga tttaggaaac attctaagtc ctcgctccca ttctgtcata ccttcggact
     4921 tagaattgat agtagccata atcataccac ttaaataata tgtttgatca tcggcataat
     4981 ttttatttat tgtctgcttc acaatatttt gagcattatc ataattacca ctagtcatat
     5041 catctttgat caatttatta taaatattat cttctttaat tgtaaaaatt ctaatttgaa
     5101 gtgcaataaa tataacaagc ataccaatta gtaaaatcca aaaaatatta cgattcactt
     5161 tatagtaata gccaattaaa gttattaata aaccaccaat gaatcctcca atatgcgcca
     5221 caatatttat atttgacata aacagagaaa caccaactaa tatcactaat gcaattaata
     5281 actgtcctaa catttttttg ttaaatgttt ttgaaacata catcatcgca aaaattgatc
     5341 caatcagacc aaatatagca ccactagccc caactgaaat tgtagtcgta ttaaatgata
     5401 gtgatacaaa gtttccaaac aaccctgcaa taaagtatac agttaacatc cgccatgaac
     5461 caataattgc ttcgactatt ttaccaaaaa taaataatga aagcatattc ataagtatat
     5521 gttcaaaact aaaatgtaaa aacatcgatg taacaattcg ataccattca ccatgtacga
     5581 cattaaaatg cactaacccg ccaacatcta ataattttac atccgaaaaa ttatttaaat
     5641 ataaaatcat acataaccat attaagacat ttacaaatat tattgtgtat gttgccggtg
     5701 aaaatttctg catatattta tctaaaaagt tatcggttaa tactttgcgt ttatagaaca
     5761 tatatgtctt tttatcatta tcttctgaaa taagtctagc caaaaatata ttcggcatat
     5821 gctttatcaa atcttttgtg tgtcttataa cattgaattt aattctaatt ggcgaaactt
     5881 catttaattg ttcttctgaa aattccgatt ctgtaaaata ataaaattca aaactttgtg
     5941 gttcgaaaga aataaaattt gctatttcat ctttgtgttc aagcactttc gctttgtcaa
     6001 aacgtatttc ttgggtagac ttgatatgtt gtttaaaaat gactacttgt ttttttcttt
     6061 tatgggctaa ccaaatttct tggtcatctt tttccctact gacaatatca aaattcaagt
     6121 acctaatcca ataatatatt gttttccaaa attgtttgtc tatgttcatt tagtcctcca
     6181 ctatgctgat tgatatataa tcaatttatc gactggttga tcgaatgatt ccggttcaaa
     6241 tgatgttatt tgaaaatcgt ataataagct tattgtcttt gtctgataat tagctaaaaa
     6301 cctgtcgtaa tagccaccac catacccaat tctatatcca tcgtcttgaa atccaacacc
     6361 aggaacaaca attaaatcta ggttattcgt tgtttcacct tttgaagttg gatagtaaat
     6421 ccccttatta tcgacatcaa tatctttgag attaaatatt tctttaaaag tcatttgatg
     6481 atttaaataa tccattttcg gtacaaaaat acgtttatga tccattaagg cttgttcaat
     6541 aatagaaaaa gtatctactt catgattaaa agaaagaact agcgcaattg cgtttgcttc
     6601 tttgtattct tcagttgcaa aaaattgatt tcttaaccat gtgtctgctt ttcgcttttc
     6661 agctttatta aaattcttca ttttatgtaa aatgtatttt ctaatctcat ttttagtcac
     6721 attatcaccc actttattca attctattat atcgttaata acaatacatg tcattatgtt
     6781 gtcatgatga attatgcgac aattctaaaa tttattattt caattgaaaa tcttttatca
     6841 tttcatacgt gtgcataatt aaaaaggtga aacctcttat tttgagattt cacctttttt
     6901 attgttaatt taaatttaat tttaatgatt attttgtttc acggtgtaaa gtttgtttgt
     6961 tttcacgtga acagaatttc ttcatttcaa cacgttctgg attatttctt ttgttcttag
     7021 ttgtaatgta gtttctgtca ccacattccg tacaagctaa agttacgttt acgcgcatgg
     7081 ttattcctcc ttatcatttc taaatacgac tttattatta taccaacatc tataatattt
     7141 gcaaagttaa aattttacaa ccatgcgcta cacaatcgtc aggttaaatt ttatttgtct
     7201 ttgtctttat ttttatcatc tttacctaac tgcttaaagt agtagttaat tacatctcta
     7261 cctaagtctc cacctgttaa ccatggtggt ggtacaggct gatttgtata tacaattgaa
     7321 aacgctaatt ttggatcatc aattggcgcg tatcctatat aagtagagtt aactcttggc
     7381 tctccgtttt ggaacacttc agcggtaccc gttttaccag cagtaggtac tactgtatct
     7441 ttaaaactaa catatccagt accatcttta tcattaaatg ccattttgaa tccttcttga
     7501 atttgtttga tttccttttc agtattatta accttgttca agacagtgcc attaattttc
     7561 ttcttgagtg gaccaacctc atctttatta gttgattcat gaatcgttaa tccaatgtgt
     7621 ggctgtattc tataaccatc attcgctata gttgaaacat attgtgataa ttgtaatggt
     7681 gtataggtat catattgacc aattgataaa tctagataat tacctggatt atttgttaat
     7741 ggttcgattt gacctcttgt ttcatttggt aaatctatcc ctgttttcac acctaagcct
     7801 acttgattta atcctcttct aagcttttgg gcaggtgaac ttatatctga aggtaaagcc
     7861 ataccagaat aataagggtc tcccgctaat tttaatgctg ttttaaacat atatacgttt
     7921 gatgaatgca tcaaagcttg cttatcatta atagatacat gcccgttttt attgaagtat
     7981 gatcgttttg tcaaaccacc ttggaaatgt aatggttcat cgaccattgt ttctccaact
     8041 ttgatagctt tattctgata accagctaat aatgttccac cttttacaga agatccaacc
     8101 gcaaattgag aagtaaacgt accaatgtca taatcagtca ttttaccact cttattaatc
     8161 tgctttccgg caagcgcaag aatgtctcca tttttaggat tttgtacaac catcatagca
     8221 ttatccatat cttttgcacc ttggctgcga agcttcttaa tttgtttatc taataatgct
     8281 tctacttctt tttgaagatc tatatcgatc gttaatttca aatcttgacc gcgagcgcca
     8341 ggatttaaca cttctgaaga tgtaacttta ccagatttgt ccgttgtgta tttcatttct
     8401 ttcttcttac cacgcaatac atcttcatat tgatattcta ggtaagattt tccaacacga
     8461 tcattgcgtg aatatccttt ggataagtaa tgttctgtca attcttttgg aataccttca
     8521 gcaggtgtcg atacatctcc gaatatacct cttaaagtat cgccatatgg atattttcta
     8581 tcccaatcca tagacgtgtt aacacctggt aatttggaaa gttgctgaga aactgctgca
     8641 tactcttttt cactgacatc ttcatttttt atcatttgtg gatctaaaac tgttcctgca
     8701 ttcatctctc gaaaaatagc taaaacttgt aaatctttag aagacaattc atctaattgt
     8761 gattttccga ttttcgataa cagttgttta tcatattgat cttgtttaat acttccatct
     8821 gctaacatag cttgttcttt tgtcatcatt gcttttgctt ttttaggatg caactgaatc
     8881 cagaaatctt tcttatcacg ttctgtaatt ttcttagtat ccatcttgat tagctttgat
     8941 aacttttcag ccgtatccaa catttccgat tgtgttgttt ttcgacccct agtatatgta
     9001 atagccattt tagaagcatt atcaactaaa actttcccat ttctgtctaa aatacgacct
     9061 cttggcacag actcattcac tgtaatgttt tcatcatttt ttataatttg tttataatgt
     9121 gagccttgtg cgatttgtaa ataacctaaa cgtagtacta gtactgcaaa aataaataca
     9181 atcacaccaa atataaagtt aattctcttg ttaattgtat tttgaacgat ttcatcattt
     9241 gatttttctt ttagtctttt taacaaaact acctacctct attcaaagtc tttcacttta
     9301 aatcatatat gaatttagaa attatttcta tctttttgac aaaaaaataa cggtctcatt
     9361 taagagaccg aacaagtaat catactttat tttgttgcat tatataattc gtcaactttt
     9421 tcccagttaa ctacattcca aaatgcgcca atgtagtcag ggcgtttgtt ttgatatttt
     9481 aggtaataag cgtgttccca tacgtctaaa cctaaaatag gtgttttacc ctcagttaat
     9541 ggattatctt ggtttggtgt agtcacaatt tctaactggc cattgtttac gactaaccaa
     9601 gcccaacctg aaccaaagcg tgcagctgct ttgtcagcaa attctttttt aaattcttct
     9661 aaagaacccc attgttcttt aattttttct actacagtac ctttttcttc tgagtttggt
     9721 gaaagtaact cccagaataa tgaatggttt aaatgtccac cgccattatt acgtacagca
     9781 gtttggatgt tagctggtac actgtctaaa ttagcaacaa tttcttcaat agatttagat
     9841 tctaaatctg taccttctac tgcagcattt aatttcgtaa catacgtgtt atgatgtctg
     9901 tcatggtgaa tttccatagt ttctttgtca aaatgtggtt ctaatgcatc aaatgcgtat
     9961 ggtaattttg gtaattcaaa agccataaat aatcatcctc ctaaaatgtc tgtaagtaaa
    10021 taataacaag cagtgactgg ttcaacaaag aatttgctta aattctacta cttattattt
    10081 tctctactca tttaatataa ctcaaatcaa aaataattaa acattttgta tataaaaagt
    10141 taacagattt gccataaaat catacgaacg gagtatgaaa tgaaccttta tcttctataa
    10201 tttaaaaaat gagatttatg catacatctg accaaatgtg cataaatctc atttctttat
    10261 attaatcttg gcaagactca catacaccat aaacttcaag tttgtgtttg tgaatattaa
    10321 caccaggtag tgataacttt atctgatcta ttggacaata atctattacc tttgtatctc
    10381 cacacttttc acagataaaa tgatgatgat gatggtttgt acaagcgatt ctaaacttca
    10441 tttcaccatc aagttctgta ttttcaataa tccctaaatc tttaaataag tgcaggtttc
    10501 tatatattgt gtcgaatgaa attccaggat aattttcatc cataacttgt tgtatatact
    10561 ttgcgtttat atacttatct tcttcgacaa aaatatctaa catatcttta cgtttatctg
    10621 tatattttaa accgttctct tttaaaattt taatagcatc atttgtattc attgatatta
    10681 gctccctttt taaacttcat tcgcattttc tgataagcca ttgtaatcat aagtaaaata
    10741 actagtagaa ctacaattac accacccgga gaaatgtcca tatagaaagc taggactaag
    10801 cctaatatta ctgataattc acctaaaaat acacttagta atatcaattg cttaaaactt
    10861 tttgttattc gcatacttat tgcaattggt aacgtgatta aagcacttac taacagtatc
    10921 cctacaacac gcattgaggc agaaataacc atcgctacaa taacaataaa taaaaattga
    10981 atccatttat gaatgccaat gactttacta tattcctcat caaatgacaa tataaataat
    11041 tctttataaa acaatgtaat aaacagaaca actatgatgg caatgacaat aatcgttgtt
    11101 aaatcactta tattcactgc gcttattgag ccaaatagca atccaacaat ttcttgattg
    11161 aacccatcag ctaatgaaat gaagattgca ctcaaggcga taccagcact cattataatt
    11221 ggaatagcaa tttcttggta agcagtgtat gacgttctta atttttcaat tagaagcgca
    11281 cctactattg cgaataagat tccaaaccac attggattaa taaatactag tgttggcata
    11341 atagtaagta aaaacatacc gaaggatata ccacctaaag ttacatgact tagagcatca
    11401 gctataagtg atagtcgtct aacaacgata aaagcaccga ttagaggcgc aataaaacct
    11461 atcaagatac cactaattaa agagtacctc ataaaatcaa aattcaataa tgcatctatc
    11521 aattgtgaca cgcctttcca ttttaaataa actcaaatct ttattaatta caacattctc
    11581 gattatgctg atgatcgaca aaacgtacag gatgtccata aatttttgaa atttcaactt
    11641 catcaagtga tttaaactca tcagttgtac catggaaatg caaatgctta tttaaacatg
    11701 ctacttcagt agcagtatct gctacaacac cgatatcatg agtaactaag ataatggtga
    11761 taccttcttg ttttaattga tctaaagtat tataaaattc acttacatgt tttgcatcaa
    11821 taccattcgt tggttcatca agtactaata ctgcaggttc tgaaatcaat gctcgggcaa
    11881 tcattacacg ttgttgttga ccacctgata attctgctat atttttatga attaaatcac
    11941 ttatattcag tctttctagt actttaatca ctttttcatt atctttgcta ttaaatgttt
    12001 ggaaaagacg ttttgtcttt gttaatccgc ttaaaacaac ttctttaaca cttgctggga
    12061 aacctgaatt aaaggcattt gctttttgtg atacatagct taatttaatt gatgttttct
    12121 tatttttaaa atcaatacct tcaacaaaaa tctcaccact ttgtaaaggt aataacccta
    12181 gaatcaactt caataatgtt gatttaccag caccatttgg tccaacaatc gctaaaaatt
    12241 cacctttatt tattttaatg tttatatttt ctaacacttt tttatgatca tagtagtaat
    12301 tgacattttt caattcaaag actggtgtca tcgtattctc acctcgcatt caactataca
    12361 actcctagta acatatgtaa acagtaatgt ttacgactca aaattagaca aaataaagag
    12421 atatgccccc ttcaagtttt atttatcgca tttcttgaag agagcattat cattttattg
    12481 ttgcataacc ttatttttta attctgggtc aaattgctgt tgttttaaca tttcaatttc
    12541 aagtttatat ggcggttttt tatttttctt atcttcacca acataaggtg tttctaagat
    12601 tttcggaata tctttaaaac tatcatgatg cacaatgtaa tttaatgcat caaaaccaat
    12661 gtaaccgaag ccaatatttt catgtcggtc tttttgagcg ccacggtcat ttttagaatc
    12721 attgacatga acaactttga ttctgtcgac tccaataatt ttatcaaatt catttaatac
    12781 gccatcaaag tcctctttca cattatatcc agcatcatgc gtatgacatg tatcaaaaca
    12841 tactgataaa cgttcgttat tatgaactcc atcaataata cgtgctaact cttcaaacga
    12901 gcgaccaatc tctgtacctt tacctgccat cgtttcaagc gcaatacgta cattattgtc
    12961 attcgttaaa acttcattta atccttcaat aatcttatta attccggcat caacaccagc
    13021 tccaacatgc gcacctggat gtaatacaat atctttagcg cctatagctt gcgttctttc
    13081 aatttcttgt tgcaagaaat ctacaccaag attaaacgtt tctggtttgg ttgtatttgc
    13141 aatattaatg atgtatggtg catgaacaac aatattagat aagccatatt tttccatcac
    13201 ttcatgacct ttagttatat ttaaatcttc aatactttta cggcgcgtgt tttgaggtgc
    13261 accagtataa atcataaatg ttgtttcacc atattcatac gcttctatag cagaaccttc
    13321 taacatcttt ttaccactca ttgaaacatg tgatcctaat aacataaaac acacctaacc
    13381 ttttttgttt tgcttacgtt tttgtctatt ttgctgctta ctaaattgtt tacgctcttg
    13441 acgtttcatt ttttcaactt cttgtttaaa tttcttctta taacctggtt taactttgtt
    13501 tttaatttta cttcgaactt tgttcttcac ttgattagtt aaatggtcat ctttgcgcat
    13561 tcttgcttga cgctgattgt gcgctttaac ttcttttaac tcaccatctt taatatcaac
    13621 agtattgaat acaaaaccgc gatcttctat taatgaaata ttgtgttctt catcaggact
    13681 ataaagcgta attgctacac ctttataatt cccacgacca gttcgtccaa ctctatgcgt
    13741 aaagaagtca atatcatttg gcacatcaaa attgatgaca tgactaacac cttcaatatc
    13801 aataccacga gatgctaaat cgctggcaat aacgtattgg aattctaaat tacgtatacg
    13861 tttcatttgt tgtttacgtt cacgtggcgt taaaccacca tgaatcatac caactttaat
    13921 accagcttca tttagtgaac gtgctaaatc atttgcatta tctctactat tacagaaaat
    13981 aatacataag tatggattta gtatatcaat taaatttaaa gttttttcaa ctttagctgc
    14041 acctttagta ggtattaaaa agaattcgat gttcttttta ttttgttttt tactgtcgac
    14101 agctacatat tctggatgac ttaaatattt atttaaaaat ggttgtaact gttgtggaat
    14161 tgtagcacta aacaccgcaa tatttgcatt atcttccaat cttgcagcaa tgtaatctac
    14221 atcttcaatt aatcctaagt caatcataag atccgcttca tcaataacta aatatgatgc
    14281 taagtgcaca tgtaaatgtc ccgttttagc taagtcatta attctagtag gggtgcctat
    14341 aatcaattgt ggttgtgcat tacaacgttg tctatctttc tctatatctg taccaccaat
    14401 aaaaacttta actgaaacac cagctttaaa ttggcttaaa tggttcgctg catcgtatag
    14461 ttgttgtgca agttctcttg ttggtgcaac tacgattgct tgtggttctt ttatttcact
    14521 atcaattaac tgcattaatg gtaataaaaa tgcatgagat ttccctgtac ccgtttgaga
    14581 ttgaccaatt aaatttgttc tctttagtat tcttggaata attcgattct gaatttcagt
    14641 tggtttttca aaattaaggt ctttcacagc gtcaattaaa ctagattcta gattaaattg
    14701 ttcgaatgga tgttttgcca tgatttggcc tccttatatg ttcatcttta ctattataaa
    14761 gtataaatgt gctattttaa ataaaaatat taaaacctcg aaatttcaaa atttagaaat
    14821 cccgagattt tagtttaaat atattgaaat ggatctgtat taattgtaga tgcttcaaca
    14881 tctatattta ttttttctat attgaaccaa ttcattagta acgtttttaa accttctttc
    14941 atcacatatt cgctgtaatg attaatatca attaaattca caccatgaat tttagcatct
    15001 aaggcatcat gatgtttaat atcacctgta acaaagacat ctgcgccttg ttggacagct
    15061 tgatattcat atccaatacc tgaaccacca ataattgcaa tacgtttaat tttctgatta
    15121 gactcaccaa caaaacggac acttgggata tttaatttag atttaatatc agctgcgaaa
    15181 tcttccaatg tcatttgatt atccacttct gccataacgc caagtccata aagggatgtt
    15241 tgttttatct caataaaatc aaataccggt gtttcatatg gatggtattg tttaattaat
    15301 tgctcagccc ttgacttttg atatgcatct atcataaatt caattttaac ttcatctaca
    15361 tcttcaattt tatcaatttg tcctattgtt ggattagctt caccaactgg tttgaattgc
    15421 cctcttcctt cactttcaaa gaaacaatat tcataattac cttcttgcgc taatccattt
    15481 tcactaagct tatctttaaa tggtccaaca ttatccttag gtatatatgt ttgaacttta
    15541 tagtatacat cttgttgatt atttattatt gaaatgttct tcaaacccat cgccttcgcc
    15601 aacatcatat tgacaccata cggatttaca tctaaatttg tatgcatcgc tattaaatta
    15661 atgtcatgtt gaattagttt tctaatgatc aaaccataac cattagcttt taatgatgtt
    15721 acgcctttaa agattagagg atgatgacta ataatagtat tataaccttt ttcgattgct
    15781 tcatttacta cttccaacgt acagtctaat gctgttaaaa caccagtaac ttcaacatct
    15841 ccatcaccta ttaacaatcc tacattatcc caagattcag cagtactaaa tggcacatga
    15901 tgatctaaca atgtcattaa atcagctatt ttcattacta taacaccctt tcaattacag
    15961 caatttcgtc attaatttga gctaaacgtt gatgatgttg ttcagtattg agtttcgatt
    16021 taatatgata aagtgcttct aactctcttt gccatttttt tataaaatat tcatttttgt
    16081 tgttcagcaa ttttggtccg aatttcaatt catcagatga tagctctatt aattgtgtag
    16141 aatgttctgc tacaacaatt tcataaatat ggcctttttc ttccattatt atttcatcaa
    16201 ttatttcata attcaattgt tgtaatgttt gtcttaaatt ttcagtttgt atattacttt
    16261 gtaaaatcaa ccttggatgt tgacttaact tatcttgccc atcttttaaa attttagcaa
    16321 taagtggtcc gcccatacca caaattgtga tattatcgat tacgtcctca ggatgaataa
    16381 cacttaagcc atcccctaaa cgtacatcaa ttctttctac taaatgattt gcagctacat
    16441 ttttcacagc agcttgaaaa gggccttgaa taacttctcc agcaataccg cattcgcata
    16501 aatggttttg aattgcatag attggcaaat aagcatgatc tgagccaata tccgcgattg
    16561 taccttgttt taaaaatcga cttaccgtcg ttaatcggtt atttaacgaa atcattttat
    16621 tctcctttat gaaaaaagag gttgaacatt attcaatgta ccaacctcac tcaagttaaa
    16681 tcttaatcta aaaataaata agcgcttatt catgtcttgg tatcaatcat taaaattgat
    16741 ataaattaat ccataaagtc tttcaaacgt ttactacgac ttggatgtct taattttcta
    16801 agtgcttttg cttcaatttg tcgaatacgt tcacgtgtaa caccgaaaac tttaccaact
    16861 tcttcaagtg ttcttgttct gccgtcatca agaccaaatc ttaatcgtaa tacattttct
    16921 tctctatcag ttaatgtatc aagcacatct tctaattgct cttttaataa ttcataagca
    16981 gcatgatctg aaggactttg tgcttcctga tcctcaataa agtctcctaa atgactatca
    17041 tcttcttcac caattggtgt ttctaatgaa acaggttctt gcgcaatttt taaaatttca
    17101 cgaacttttt ctgctggtaa atccatttct tcaccaattt cttctggtgc tggatctcga
    17161 cctaagtcct gtaataattg acgttgaaca cgaattaatt tattaattgt ttctaccata
    17221 tgcacaggga tacgaatcgt acgtgcttgg tcagcaattg cacgagtgat tgcttgtcta
    17281 atccaccatg ttgcatatgt tgaaaactta aatcctttgt taaagtcaaa tttttcaaca
    17341 gctttaataa gacccatatt accttcttgg attaaatcaa ggaataacat accacgacct
    17401 acgtatcttt tagcaatact tacaactaaa cgtaagttcg cttctgcaag tcttgatttt
    17461 gctacttcat caccttgttc aatacgtttg gctaattcga tttcttcttg tgcacttaat
    17521 aagttaacac gcccaatttc tttaaggtac atacgaactg ggtcatttat tttaacacct
    17581 ggaggggcac taagatcact tggattcagt ttctcgtcag tatctgaact atctttttca
    17641 ttaactagtg aaatatcatt atcatttaat tgatcaaaga aatcatccat ttgatcagag
    17701 tcgatatcaa aattctgaag tttttcagca atttcttcat gacttaaatg accctctttt
    17761 ttaccttttt caattaattg cttcttaaca tcttctaatg ttaatgtcgg atcaattgtt
    17821 tgttttttaa ttttaactgt gttatcagac atgaaacggc ctcccgattt taaatatgaa
    17881 cattcgaaat ttattcaata ttgctatttt aaactaaatt cttaattaat tcatccatat
    17941 ttttaatttt attttacaaa ttggaactaa tcccaatatt tatttttcaa tagtgttgtt
    18001 taaatgcggt aactatcatt tacccttata cattttgaca taatcattat tcgtattatt
    18061 ctttaaaatc acatgctaca tgcgttcttt attcttagca acaatttgct gtaaatagta
    18121 tttttgtaat tctacatcgc caatccttgt agcttccctt aatttatgat tcaatgactc
    18181 aattgtttct tgtccttttt cattaataac attgacataa tcatcaattt cattttcata
    18241 tggttcgtca ttcaaattat attgttctaa gctaattagt gtttctctca actcatttga
    18301 attaacatac tgcacagcat cactgatatt atattgatca ttttccgcat aaaaatcatg
    18361 taagacttcg aatacatatt taaaatgctg atttgtgaag ttatccttat caacactttc
    18421 ataataattt aaaaatgtat ctttatctct cattaaatgt tttaaaaatg ctcgctccgc
    18481 tttttcttga cggctcaaat tgtcaaattg tgccatacca attggctcag gttcaatata
    18541 accgccatac tcatcataac cgccatactc atcttctgga taataattgg ctggtgcttg
    18601 attgaattgt atttcgttag ctaactgctc aggactaaca ttgaaaaatg gcgcaacatc
    18661 atttatagcc ttttgttgca gaattgatga cttcataagt gaaatgtcat gactcagttc
    18721 tttcaaataa cgttcatatg aaaggtcatt atgtgcaatt tcatctttta atatacttac
    18781 tttataatgt gcaaatgact ttttgtcatt ttttacaaaa gtagtaaatg cgtcgttgcc
    18841 atacttacca atgtattcat ccggatccat gccagatggc aattgtataa caaatacatt
    18901 tagcccttgc tgtaacaaat gttgacctgt tttaagtgtt gcttcactac ccgcaaaatc
    18961 cccatcaaac attaatgtta tatttgatgt taactttcgt ataaaggtaa tatgttcatc
    19021 tgacaactgt gtacccattg ttgcaacaac gtttttcaag ccagcagtat cagattttat
    19081 aacatccata aaaccttcta gtaatacaat ttcatctaat tttctaattg atttacgtgc
    19141 tttatctaag ttatataaca actttctttt ttgaaagata ggcgtttcag gactatttag
    19201 gtattttggt tcttgaccgg tatatgttcg acctgaatat ccaacaattc ttccttgcgc
    19261 atttttcaaa ggaaacataa tacgatttcg aaatctatcg taataactga aattttcttc
    19321 gttacgtgat aataatccgg cttcatatgc taattcaata tcgtaaccct ttttttgaag
    19381 aaaatcatga caaaaatgtg agctatcggg tgcaaagcca atgcctcgct ctttaataag
    19441 cgcatctgta aaaccacgtt cttgtaagta tgttaatgct tgttcgcctt cgactgtctt
    19501 tgttaaagcg taataataaa attcttgtat taactcatgc atttcaatca tttgtaaatc
    19561 atcagaagca atttgaacat ttgagttaga ttgtgttgcc tcaatatcta cagcaacatt
    19621 aactctatca cctaattctt taaccgcttc aacaaatgat atgtctttaa tttcttgagt
    19681 aaattgaaaa acattgccac cttttttaca accaaaacaa tgacagattt gtttatcttc
    19741 agaaactgta aatgaaggtg tcttttcatc atgaaaagga cacaaaccta tataattgcg
    19801 tcctctcttt tctagtttta catattcact taccaagtct aaaatgtcgg ttttatcttt
    19861 tatttcatta atgatcgatt gatctattcg caaattaaat cacctattaa gcattagtta
    19921 tactattata cctaattttt gacaaaaatg aaatcatttc gatttatttt gttcaatata
    19981 atggattata tcgtttgctg tttcttcgat tgctttttga gaaacatcaa tgacaggaca
    20041 tccaatttca cttacgattt cttcaaagta attcaattct tcttggattc gagcttctgt
    20101 tgcataacga gctgtgtcac ctagtcccaa ttgttttaat cgctcttttc taatgcgatt
    20161 taatttttct tcacttattt taagtgcgat acatttctta ggatcaatat catataagcc
    20221 atctggcggt gtcacttctg gtacaatcgg tacattcata actttgtaac tcttatgcgc
    20281 taaatactga gataatggtg tctttgaagt tctcgaaata ccaagtaaaa caatatcagc
    20341 tttaggtaat cctttaggat ctttaccatc atcatattta accgcaaact ctatcgcatc
    20401 aattttcttg aaatatgcat catctaatct atgaacgata cctggctcat tataaggttt
    20461 ttcttcaacc gatgctgata ataaatccat taatggcccc atgatatcaa cggacttcaa
    20521 ttggaattct gctactttct cactcatata ttgcttcatt tcaggtttaa taagtgtata
    20581 aacaatgata gcatttgtat cttttgcaac ttgaatcact tcatcaacat cttcaaaaga
    20641 ttcaatatat ggatatctta ataattcatt tttacattgc ttaggattaa attgtgaaat
    20701 acctgcccta gcaactaact ctgccgtttc acctatagaa tctgaggcta cgataatttt
    20761 aattttttcc attacttctc acctattctt tatataatgc tactaataac ttagctattg
    20821 ttgttttgga aattcttcca attacttcat acttttgatt atcttttttt cttacaattg
    20881 gaatcgaatc aatttctttt tcaatcattc tatctgctgc gtatatgact aattcgcttt
    20941 cctctaaata agtgacatta ggcatacgtg tcatatttac actgataggt actgtatgaa
    21001 tatctgctcc aatcattgaa gctcttaata aatcttttct tgaacacaca ccaacaaaat
    21061 cgttatcttc attaataata aataatgtac ttacatcttc taaaaaaatt gtacaaatag
    21121 cgtcataaac tgttgtattc tctcttagca caacaggttg agacatatag tccttaacct
    21181 caaattgtcg aagtttttca ttaaaaaatt tgccttttga tttacctgaa taataatatc
    21241 caactcgggg acgcgcttct aaaaaacctg acattgttaa tatcgctaaa tctggtctaa
    21301 gcgttgctct tgttaaattc aacttatctg ctatttgttc accagtaatg ggtcctttag
    21361 ttttaacaat ttcgatgatt cgttcttgtc tttgactgag ttctataggt cttcgcccct
    21421 tttttattca cttattatta taccgatatt tctttcatgt cacaaacaca ttaattttac
    21481 ttgcctttaa ataatctatc aattagaata aacgtacagc gagttaagga tagtgtaagc
    21541 ttaacaataa gattggcgca acgaatcatt ttaaaataaa agcgagtgac tacactaatt
    21601 tgggtggaac cgcgggttaa atacgtaact tattttgtat tatatacaat ttaaaatatt
    21661 aactcgtccc atggaagtaa agcatattta ctatgctgtt attttccatg gggcgttttc
    21721 atgtatgagg agaggtaatt atggcaaaag atatggatac aattgtttca ttagcaaaac
    21781 acagaggttt tgtgttccct ggtagtgata tttacggtgg tttatcaaac acatgggatt
    21841 atggtccttt aggtgttgaa ttaaagaata atgttaaaaa agcttggtgg caaaaattca
    21901 ttacacaatc accgtttaac gttggtatcg acgctgcaat cttaatgaat ccaaaagtat
    21961 gggaagcttc aggacactta aacaacttca acgacccaat gattgataat aaagatagta
    22021 aaattcgata tcgcgctgat aaattaattg aagattatat gcaagatgtt aaaggtgatg
    22081 aaaacttcat tgccgatggt ttaagttttg aacaaatgaa aaaaattatt gacgatgaag
    22141 gtattgtttg tcctgtaagt aaaactgcta actggactga aattcgccaa ttcaatttaa
    22201 tgtttaaaac attccaaggt gtaactgaag attctacaaa tgaaattttc ttacgtcctg
    22261 aaacagcaca aggtattttt gtaaactata aaaacgtgca acgttcaatg cgtaaaaaat
    22321 taccatttgg tatcggtcaa attggtaaat cattccgtaa tgaaatcact ccaggtaact
    22381 tcattttcag aacaagagaa tttgaacaaa tggaacttga attcttctgt aaacctggag
    22441 aagaaatcga atggcaaaat tattggaaaa cttttgcaag tgactggtta acaagcttaa
    22501 atatgagcag tgaaaatatg cgtttacgtg atcatgatga agatgaatta tctcattact
    22561 caaatgcaac aactgatatt gaatataaat tcccatttgg ttggggtgag ttatggggta
    22621 tcgcaagtcg tacagacttc gacttacgta aacatgctga acactctggt gaagatttca
    22681 gataccatga tccagaaacg aacgaaaaat atattccata ttgtatcgag ccatcacttg
    22741 gtgcagatcg tgtaacatta gctttcttat gtgatgcata tgatgaagaa ggcgttgaag
    22801 gtagtaaaga tgcacgtaca gttttacact tccatcctgc attagcacca tataaagcag
    22861 cgattttacc tttaagtaag aaattatctg gcgaagcgat taagattttt gagcaattaa
    22921 gttctaaatt ctcaatcgat ttcgatgaat cacaatctat cggtaaaaga taccgtcgtc
    22981 aagatgaaat cggtacacct tattgtgtaa cattcgactt tgattcatta gaagataatc
    23041 aagttacagt acgtgacaga gattcaatgg aacaagttcg tatgccaatc tcagagttag
    23101 aagctttctt aactgaaaaa acaaaattct aattaaaaag actttccacc atatgtggtg
    23161 gctatataat ttataaaaag agatactggt tagtaaaatt gccagtatct cttttctatt
    23221 caaaaaggta ttcaaataaa cacatctatg tggctacttg aatacctttt attattttat
    23281 gttattgttc caatcttttt aattggttga ttagtttctg acttttaaaa aacatacctg
    23341 catattcacg atataacatt aaaatgatat ctgacatttc atcaataatt tcttgatgga
    23401 tattcaatga attcatttta tctatcggta atttttgtaa tacatctaat aaatatagtg
    23461 ttttattcga taatataact gcatgtacat ctttagaagc ctcttgcctt gaaatcgcac
    23521 cgtcaaactt aaaactataa cctattaaat ctgcttgtgt gtcattacca ctcacagcac
    23581 agcgattaaa tgatgcagta aaaccaaatc gtttcatgca ctttaacata actacgactg
    23641 acattaactg tgcagatgta cctgattcta ttttttcaag aacaaattgt aataattgat
    23701 agttatatgg tgcaatgtca ccttcatcca ttgagcgctc aatagtttca gctgccagag
    23761 aggcataact gcttacgtaa aggtccattt gtaatttata atgttgacta ataacatcta
    23821 cagaatttaa cgttcccata cctcgccact gattgtaaat aaacaaacca taaacaaaca
    23881 attgcgtttg cgcttgtaaa cccgtcttaa cttttttagc acgccttgcc ataagtggta
    23941 cttttgcacc atgctcattt aaaatcgtga taattttatc agattcacca taatcaactg
    24001 ctttgatgat aatccctttt tggcgcatta acaattatct tcaccacttt taagattaat
    24061 cttggtcttc aacataacca atttggcgaa taaagttaac tttgtttcgc cagtctcttt
    24121 gaactttgac ccataattct aagtatactt tagagcctag aagcatttct atatcacgtc
    24181 tcgcacgttt tcctacttct tttaactttt taccgccttt tccaatgaca attccttttt
    24241 gcgaatctct ttcaacatat atagttgctt cgatatgaac acgatcttcg ctttctttaa
    24301 ccatacggtc cacattaaca ccaatcgcat gagggatttc ttcacttgta agatgaagga
    24361 ttttttcacg aatgatttca cccactacaa attgttcagg atggtctgaa atttgatcat
    24421 ctggataata tttaggtcct tcgggtaaat acgtctttaa aacatcaata aaatgatcta
    24481 catttagccc ttctaatgct gaaataggta caatctctgt aaagtccata taactttgat
    24541 attcttcaat ctttggcatt aattcatctg gatgcactaa atctatttta tttaatacta
    24601 aaaatactgg tgtcttaaca tttttcaaca tttctataat atattcatcg cctcgtccaa
    24661 tttcctcatt ggcattaacc ataaacatga ttgcatctat ttcagataat gtatttttag
    24721 cgactttcat catatagtca cctaatttgt gtttaggttt atgaatacct ggcgtatcaa
    24781 tgaatataat ttgcgcgtca tctcttgtca taacaccttg aattttattt ctagttgttt
    24841 gagctttatc ggacatgatt gctattttat ggccaatcac tctattaaca aatgttgact
    24901 tccctacatt tggtctacct ataattgaaa caaatcctga tttatgttct gtcatttatt
    24961 ctaaatcctt tcctgaaaat ccaaatggta gtaactctgc gactgtcatc ataaccatat
    25021 ctcctttatg atttgtcata tacacaggca tatcatcatc acataattcc tttaaaactt
    25081 gacgacatgc accacaaggt gatgacggtt tatctgcatc tacggttaca gttattgatt
    25141 caaaatcacc tggtctgtat ccttgagaaa ttgccgatac caaactagct cgttcagcac
    25201 atatcgataa tggataagaa gcattttcta cattggtacc ataaaaagtt ctaccgtctt
    25261 tcgtttttaa ataagcccct actttaaatt gactgtatgg cgaatatgat tcttgttgtg
    25321 cttttctaac ttcttgaaaa taatgaggtt gataactcat atatgcctcc ctaaaataac
    25381 gctataaaat gtggtaaaaa tactattaaa cctataataa atgctaatat tgaaactata
    25441 agtacactaa aagccgctat atcttttgcg tatttagcta aatcatgata ttcaacggtc
    25501 actaaatcga caacatattc aatagcagtg tttaaagctt caacagtgag aactaatgca
    25561 atagcaatga gtataaatat ccactcaata cgattaatat ttagtacgag accaaagaca
    25621 atagcaacaa tcattgcaaa cacatgtaaa agaaatttat agtctttttg aattaagatt
    25681 ttcagcccat caagtgcata tttaaacctt ttcataatta gtctcgtgtt aatccataag
    25741 cgtttaatat tgtatcttgt cgaccaaaca tttccttttc atccgcttca gtcatatgat
    25801 cataacctaa tagatgcaaa aatccatgta atgctaaaaa tcctaattct cgttcaaaag
    25861 aatgtccgta attgtttgct tgttcttgcg ctacatccgt acagataatt atatccccta
    25921 aaacacgtgg tatatcaaga ccactaaaat caatctctgg ctcatcttct tctaaagcaa
    25981 atgagattac atctgtaact ttatctttat ctctatatgt tcgattaatt tcttgtattt
    26041 cttgtttatc tacaaatgta acagaaagct cagcatcgtc ttctatatgc tcttcttttt
    26101 tagcaaattc taataaatct tcaatttgtt tataccacgc atctttaact aagcctgtgt
    26161 gatcgctaaa atctatcgta aacatttaat tctctccttc ataatgttca atgatcttac
    26221 ttaccaatgg atgtcttact acatcgctct gatctaattt caatatactt atacctttaa
    26281 cgttgtgtaa cctactgacc gcttccttaa gtccactttt aacaccttta ggtaaatcga
    26341 tttgagtttg gtcaccagta actaccattt ttgagccaaa acctagtctt gttaaaaaca
    26401 ttttcatttg cgcatgtgtc gtattctgcg cctcatcaag aattacaaat gcatcttcta
    26461 atgttcgtcc gcgcatatat gcaagtggcg ctatttcgat aatgcctctt tcaataaatc
    26521 gctctgtttg ttcacgccca agaacagtat atagaccatc atataaaggt cttaaatatg
    26581 gatctacctt ttctttcaaa tctcctggta aaaatccaag tgactctcct gcttcaacag
    26641 caggtcttgt taatacaata cgtttaacag cacctttacg gagttgcttt gctgcataaa
    26701 ctacagctaa gaatgtctta cctgtaccag caggacctat accaaatact aaatcattat
    26761 ttttcatggc attaacatat atacgttgcc ccatcgtttt cgcacgaatc gtcttaccaa
    26821 atgcatcttt agttatctct tcatcatata aatctaacag atgttgaatt gtgttattat
    26881 gcgccatttt aatagctgct tcaacatctt taattgtaat attattacct aaatcaataa
    26941 ccttcagcaa attgattaat actgattccg ctttttctac gttttctatt tttgtacctt
    27001 taacggcaac ttcttgtcct cttgcatgga tgacaacatc gaaactctct tcaattgctt
    27061 ttaaatgttc atcattattt ccaattaaag cttgagattg gttcatatcg tctatttgta
    27121 taattccagg catacacgcg ctccttttca tatatcattt atattcattc tatgatgctt
    27181 taatatctac ttaattatat catgcaattg attgatttaa acatctttgc attgacttac
    27241 tcatttttct ttaatttaaa ataatcattt atacttttca ccttgtcata aaagcagttt
    27301 caattttaga ctaatcaatt ttttgctgta atttaaataa ctaatatttc tcgaaagatt
    27361 ctctttgttt tttaattttt cttaacgtaa aaaaacaagc aactaccatt acgatagtgc
    27421 ttgttttcaa aaaattttat aattgttttg gtttagctaa aatttctgac catatcatac
    27481 cattgattac ttcatcttta tcaaattgga acgctgattt agtcaaatct ttttcgacat
    27541 tttgagaatt aagcaactgc tttaatttca aacgttttgt acgttcagat aagtatttat
    27601 cctcaataat atctctagca cgtttttcca ttttagcaat ttgcttttct ttttctctat
    27661 caatgtcagt acgaatcgtt ttaatatcat ctctaagtga tttttctaat tgacgtctaa
    27721 tttcgtcaga attatcttgt ctagaaggtc tatgtttctg ctccaccggt tctgctttag
    27781 gcactgtaat tggtttctct gtcatcggtt ttgtttctgg ttgtttttta ggtgccatag
    27841 gttctacaac aggtttcgat ttaggctctt cctttggaag ttcatcgaat aaaggtggta
    27901 acgtatcatc atattttcgt ttcgatgatt tcttttcttc ttcatttaat tcttcactta
    27961 tttctttaaa cgttcgctca atttcttcaa aaaagccacc tttttttggt tcattatcgg
    28021 tagatgtttt ttgaggtggc ttttgatttt gtctatcttt atgactattt tcgcgcatag
    28081 tagtaatgat agaaatgatc actgatatga caaaaattag aataccgaca ctcatttaat
    28141 cacctctcga cttaatgttc aggtgactca tcatcacttt gatcagttcg tttattaatt
    28201 gcatttctca tgcctgtatc agcttcgata tttttcaaat tataataatc tttaacactg
    28261 atattacctg aacgtaatgc ttcagccata gctaatggta cttcagattc ggcttcaact
    28321 actttagcat gcatttcttg tacacgcgct ttcatttctt gctcagttgc tacagccata
    28381 gctctacgtt cttcagcttt tgcttgtgca atatttttgt ctgctaatgc ttgttcagtt
    28441 tgtaagtctg caccaatatt tttactaata tcaacgtcag caatatcaat tgataaaatt
    28501 tcaaatgcag tacctgaatc taaacctttg cttaaaactg ttttagaaat attatctggg
    28561 ttttcaagta cttctgtatg atgcttacta gaaccaattg ttgaaacgat accttcacca
    28621 acacgtgcga tgattgtttc ttcacctgca ccaccaacaa gtcgagcaat attagctcta
    28681 actgtgatac gagctttggc tttcacttca ataccgttca ttgctacacc tgcgataaat
    28741 ggtgtttcaa tgactttagg attaacagac atttgaaccg cttctaatac gtcacgtcct
    28801 gcaaggtcaa ttgcagcagc acgttcgaaa ggaagatcaa tgtcagcacg ttgtgcagca
    28861 atattagcat caacaactct gtcaacattt cctcctgcta gataatgcga ttctaattgg
    28921 tttgttgtta atgctagtcc tgctttgtgc gctttaatta atggcgctat aacttttctt
    28981 ggagatacac gacgtaaacg cataccaacc aatgtaccta taccaacatg aacgccagct
    29041 gctaacgctg aaatccacaa accaatcggt acaaatgaga ataaaataag taatgcaact
    29101 attataataa ctgctattac gataaaactt aaactaaaca tggtatcgct ccttttaatt
    29161 aatctacttc cctcacaact actcttgttc cttcaacttc aaggattttc accgttttat
    29221 tgcgtaaaat aaagttgcca tctgaaacag catcaatacg ttcattttca caaaaaataa
    29281 tccctgcagg tcgaagatct gtaactgttt gagcagtctt tcctacgagg tgcgagcggt
    29341 tatcatgaga attgtaacct gactcagaat tagttgaatc ttttaagata accttatcca
    29401 aaaacggaat ctttctgttg aaaatcttca ctaatatcac ccattctaca atcgttaaaa
    29461 tcaaggcaac gataacattc gcaagcataa atagcaaatt atcaccgagc gttgttatgc
    29521 ttatagttat cagtatcatg ccaataatac caattactgc accaactaca aataattcaa
    29581 ttacaactaa tataacgcca attgagaata ttaagataga atgcatattg acatttcctt
    29641 ggattagaaa tcccaaaaat aaaataagta atgataatgt ggcgataata ccagctgcat
    29701 tgattttttt agagtaaagt tgatatacaa atcctaagaa tgtcaaacag gttaatatta
    29761 acgtaaaaat aggttgaaca attatattac taacttgttc aacccaagta tctccagccg
    29821 ttgattccaa gatagttgtc atttgtaaaa aattattata actcacaatt tcacctcgcc
    29881 ctcacattaa ttatacatga aattgaatat actttatagt tataagaacc tatagaatat
    29941 caatttgatt atttataaac tatataactt tttttaatta aaaattgaca acaaaaaaac
    30001 atcacatatt agtgtcagac actaacttgt gatgtttatt ttatataatt aatattcgtg
    30061 ttgagggagt caacagaggt attaattatt tgaatttacg tttacgtgca gcttctgatt
    30121 tctttttacg ttttacgctt ggtttttcgt aaaattcacg tttacgtact tcttggattg
    30181 ttccactttt agaaactgaa cgtttaaatc tacgtaacgc atcttcaagt gattcatttt
    30241 tacgtactac tgttttagac atctgtattt ccctccctcc aaatatcaac ggaactttat
    30301 agtcaattgc acagtaaaac tatgcattta taagtataat atatctgtaa tttatggtca
    30361 attagtaaat tgttttttat ttgaaacata tttcacatca aaatcacaaa gacttttaga
    30421 ttttgttcta aaaatctctt aataatttat ttaatgagaa gagttgctta tatagtaaat
    30481 tgtgaagccg ttaaaacaac gttacaaaac ctatatcttt aatacggaac cttatggtat
    30541 gaatcaagga atacttaaac taaaacttct ctatcagatt tatttgttgc gaaatcaaca
    30601 actttaattg cttgcccttc atttaatgga taatttgctt gcgtaatttt aacttttaca
    30661 atttgaccta tgagtgattc gtcaccttca aattgtactt tcatataatt atctgcatat
    30721 ccaactaatg taccttctgt gtcaccctgt tcctcaggaa ttacttcaag cacatcttga
    30781 tcaaatttag acgcatataa ctttccgagt tgattgctta gcgtaattaa cttatgcacg
    30841 cgttcatttt taatttcttc atcaatttgg tcatccattc ttgcagctgg cgtgccaatt
    30901 ctaggagaat aagggaaaac atgcagttca gagaacttat gctttacgat aaaatcatat
    30961 gtttcttgga actctgcttc agtttcacct gggaaaccaa caattacatc actcgtaact
    31021 gccaagtctg gtaaagcttt atgcaatttt gttaatcgtt ctgaaaatct atccattgta
    31081 tacttacgtc tcatacgttt taatactgta tctgaaccag attgtaatgg aatatgcaaa
    31141 tgacgcacaa cttttgttga acgttctaaa acgtcaatta cttcatctgt aagttgactt
    31201 gcttcaattg aagaaattcg aattcgttct aatccattaa tcgtttcaag atcacgtaat
    31261 aattgggcca agttataatc ttttaaatct tgaccatatc cacctgtatg aattcccgtc
    31321 aatacaattt ccttatatcc tgaattcact agttgcgtcg cttgttcaac tactttttcc
    31381 ggatctcttg aacgcattaa gccacgagcc catggaataa tacagaatgt gcagaagttg
    31441 ttacaacctt cttgaatttt taatgacgca cgtgttctat ctgtaaaata tggaacatct
    31501 aattcttcat atttacgatt tttcatgata tttccaacac cattaattgg ttggcgttct
    31561 ttacggaatt catcaatgta acctaatagt ttatgtctat cttgtgtacc aactactaca
    31621 tcgacaccag gaatttccat aatttcagct gatgaagttt gcgcataaca acctgttaca
    31681 cagattacag catcaggatt ttgtcttatt gcacgtctaa ttatttgacg acttttttta
    31741 tcacctgtat tcgttactgt acaagtatta ataacaaata catcagcatt cgcttcaaag
    31801 tcaacgcgct catagtttgc ttctttaaat aattgccaga ttgcttcagt ttcataatgg
    31861 tttactttac aacctaatgt gtgaaacgca actgttgaca taaatattca ccccattaat
    31921 tctttttcat aacttattgc acttaacgca tacaatggcg cagtttctgc ccgtaaaatt
    31981 ctcggtccaa gaccaacaac tgtactagta ttactaaata atgaaatttc attttctgac
    32041 aaaccaccct caggaccaaa aatcatcaac actttatcct gagccttgaa ttgttgtaaa
    32101 gtttgcttga aattgcttaa cttaccatct tttgcttcct cttcatatgc aataagaata
    32161 tagtcataat tatcaatagt atcacaaatt aattttaaat tcgactcgaa ttgaatagat
    32221 ggaatcacta aacgatagct ttgttcagca gcttctttaa ttattttttg ccaacgctct
    32281 atctttttga caactttcgc ctcgtttaat ttaacaattg agcgttccat gctcacagct
    32341 ataaatgatg aagcacccaa ttcagtagct ttttgtagca accactcata tttgtcagct
    32401 ttaattagtc cactgcaaat cgtaacatca actggcaatt ctgtattaat attttgtttt
    32461 tcttttaaat caactgcaat tttatcactt gttatgtcag caatttcaca taaataaact
    32521 gtttgatcat taaaagttaa aataatttta ctaccaacat catatctcat tacatttgtt
    32581 atatgatgaa tatcttcttt ttttgtaata
//
LOCUS       DAPDIM010000030        32595 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000030 DAPDIM010000000
VERSION     DAPDIM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 32595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32595
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.030"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(167..694)
                     /gene="isaB"
                     /locus_tag="RFE25_001443"
     CDS             complement(167..694)
                     /gene="isaB"
                     /locus_tag="RFE25_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunodominant staphylococcal antigen IsaB"
                     /protein_id="HDU2816512.1"
                     /translation="MNKTSKVCVAATLALGTLIGVTVVENSAPTSKQAQAAITPYYTY
                     NGYIGNNANFILDKNFINAIKYDNVKFNGIKLAKTNTIKKVEKYDQTFKGVSAKGNEA
                     SQLQFVVKNNISLKDIQKAYGKDLKKENGKTKEADSGIFYYQNAKKTLGIWFVVDHNR
                     VVEVTVGHTPYKTSK"
     gene            952..1410
                     /locus_tag="RFE25_001444"
     CDS             952..1410
                     /locus_tag="RFE25_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816513.1"
                     /translation="MKKLLITIVIIVLIGALGFAIYAAINHSTSSSNNQEQENKSTHK
                     KTETEENDQQDDSADKTDKNQNNGNNDTNDNQPSSPSNVPNNHSTVPSNTQPAQPKDS
                     NSNKNNTHGGGSQSSTNNQNNQQQNTPPANKSNNTNTPSKQTPQAQSPKN"
     gene            1650..3524
                     /locus_tag="RFE25_001445"
     CDS             1650..3524
                     /locus_tag="RFE25_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDU2816514.1"
                     /translation="MLDRHLKLLQFFIKNPSKHISSNEIAEHVNVSNRTVRNDIHVIN
                     SNFMDDIIVSIKSKGYQLNTSQYTLETITERYTHIQSYKEKLLLSMAYQLLMHNKSQT
                     LQQLEQDYLLSKTVLNDYFVRIQQWCQKFNIVLTIKKKQGIVVDGTDNDITNAIIHLN
                     QLSSGHVHVEDLILNELPDSHQRMISHIIQETLQQHSIETTDIQIQQLLIHLILIIKR
                     KQSLSELDTLNHDAKLISQSCIKQINERLGYDLNEKVINMFSFFIAYHFNKLDIVIER
                     IFIQSYIDRLIELMQQRIHVPFNEDSILQQNLYNHFSKAYLRITQNIYLNNPLVIEIK
                     KLYPFVFNTLFEAIDKLAIDTDIEMSEDEIAFLTIHFQAAIERRTKTQLNVVIACYYG
                     LGVSNFLETKINNLSEELSVINTIKLESITHYHFDNVDLLITTHDIPKQTLNILPKHL
                     TTIKVAPLFSEDDRHKIRHVVKQKQNPVQAHHHMDTVNFLVVNTEQKSRHTVQIFEEA
                     QKILQAHHAIVEGYIESALEREKSSSTYIGNFMAIPHGDPEKVLQSHVLIFRTKDVFP
                     WRQHDVKLVFFLAISHKDKAFTKQMMQLIANLDDDSVNHLCSLDDHSLKQQLFEYLQE
                     "
     gene            3600..5552
                     /locus_tag="RFE25_001446"
     CDS             3600..5552
                     /locus_tag="RFE25_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDU2816515.1"
                     /translation="MKIVAITSCPNGIAHTYMAQEKLEQVAKEMGVDIKVETQGGVGA
                     ENVLTTQDIEEADGVIIAADKQVDLSRFVGKRLINENVREGIHNPRGLIQRIINQDAP
                     IYQSETNYHSKDRGKSKSGIQMVYQHLMNGVSFMVPFIVVGGLLIAIALTLGGETTSK
                     GLVIPDDSFWKSIENIGSLAFKFMVPILAGYIAVSIADKPGLVPGMIGGAIAADGSFY
                     GSDAGAGFLGGIVAGFLAGYIAKWIKDIKVPKAMAPIMPIIIIPIISSVVVGLIFIFL
                     IGAPISNIFEALTTWLKSMQGANIIILAMIIGAMIAFDMGGPVNKVAFLFGSALIAEG
                     NYAVMGMVAVAVCTPPIGLGLATFVQKYKFNHSEREMGKASFTMGLFGITEGAIPFAA
                     QDPLRIIPANIIGAMIASVIAAIGGVGDRVAHGGPIVAVLGGIDHVLWFIFAVIVGSL
                     VTMTTVLLLKRNTPVIAVDAPAQHTQLHDTDITQHDTEVDNVDKTAKHSHLNKPSHVF
                     DQQTMIITDHDMSRNEAIDMLIHKLKICRYVEHTSHLKNAILEREMESTTAIGMNVAI
                     PHAKSDVVKQPIVAVMKNNHGVKWDSLDGSLPQLIFLIAVPNNSQDTHLKILQRLSKA
                     LMNDETRQSLINANSTTEIYNLLMKI"
     gene            5566..6504
                     /gene="manA"
                     /locus_tag="RFE25_001447"
     CDS             5566..6504
                     /gene="manA"
                     /locus_tag="RFE25_001447"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDU2816516.1"
                     /translation="MALFLQPVFKDRIWGGHALKAFNYDIPNETTGECWAISAHPNGP
                     NTIINGPYKDMTLDQLWSQHRELFDNDSRDSFPLLTKVLDANDKLSVQVHPDDDYALK
                     HEGELGKTECWYILDAAPGAEIIYGVHAHNKQTLIDMIDNHEFDSLFKRIPVKPGDFY
                     YVPAGTVHAIGSGILILETQQSSDTTYRIYDYDRRDQNGQLRDLHLEQSKDVIELGNH
                     EPNTTPITTHIDTHTVTQFVDNQYFAVYKWDIHGDLKFNKPHAYCLVTIIDGTGTLTV
                     NDKHYDIQKGSSFILTTEDEDIHFVGNISAIVSHPG"
     gene            complement(6616..9597)
                     /locus_tag="RFE25_001448"
     CDS             complement(6616..9597)
                     /locus_tag="RFE25_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDU2816517.1"
                     /translation="MKNAFKLFKMDLKKVAKTPAVWIILAGLAILPSFYAWFNLWAMW
                     DPYGNTGHIKVAVVNEDKGDTIRGKKVNVGNTMVNTLKKNKSFDWQFVSREKADHEIK
                     MGKYFAGIYIPSKFTHEITGTLRKQPQKADVEFKVNQKINAVASKLTDTGSSVVVEKA
                     NEQFNKTVTRALLEEANKAGLTIEENVPTINKIKNAVYSADKALPKINDFANKIVYLN
                     NHQADLDKYANDFRKLGNYKGDILDAQKKLNEVNGAIPQLNEKAKLILALNNYMPKIE
                     KALNFAADDVPAQFPKINQGLNIASQGIDQANGQLNDAKGFVTQVRSRVGDYQDAIRR
                     AQDLNRRNQQQIPQNSAANNETSNSSPAAGNGVASTPPSAPSGDTAPNNNVTQNTAPN
                     SNNAPVSTTPQSTSGKKDGQSFADITTTQVSTANENTQNITDKDVKSMEAALTGSLLS
                     LSNNLDTQAKAAQKDSQALRNISYGILASDKPSDFRESLDNVKSGLEYTTQYNQQFID
                     TLKEIEKNENVDLSKEIDKVKAANNRINESLRLVNQLSNALKNGSSGTAEATKLLDQL
                     SKLDSSLSSFRDYVKKDLNSSLVSISQRIMDELNKGQTALSNVQSKLNTIDQVINSGQ
                     AILKNGKTRIDRLQTVLPSIEQQYISAVKNAQANFPKVKSDVAKAANFVRNDLPQLEQ
                     RLTNATASVNKNLPTLLNGYDQAVGLLNKNQPQAKKALSDLADFSQNKLPDVEKDLKK
                     ANKIFKKLDKDDAVDKLIDTLKNDLKKQAGIIANPINKKTVDVFPVKDYGSGMTPFYT
                     ALSVWVGALLMVSLLTVDNKHKSLESVLTTRQVFLGKAGFFIMLGMLQALIVSVGDLL
                     ILKAGVESPVLFVLITIFCSIIFNSIVYTCVSLLGNPGKAIAIVLLVLQIAGGGGTFP
                     IQTTPQFFQNISPYLPFTYAIDSLRETVGGIVPEILITKLIILTLFGIGFFVVGLILK
                     PVTDPLMKRVSEKVDQSNVTE"
     gene            9808..11667
                     /locus_tag="RFE25_001449"
     CDS             9808..11667
                     /locus_tag="RFE25_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDU2816518.1"
                     /translation="MPKNKILIYLLSTTLVLPTLVSPTAYADTPQKDTTAKTTSHDSK
                     KSNDDETSKDTTSKDTDKADNNNTSNQDNNDKKFKTIDDSTSDSNNIIDFIYKNLPQT
                     NINQLLTKNKYDDNYSLTTLIQNLFNLNSDISDYEQPRNGEKSTNDSNKNSDNSIKND
                     TDTQSSKQDKADNQKAPKSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDKANQKSSS
                     KDNQSMSDSALDSILDQYSEDAKKTQKDYASQSKKDKNEKSNTKNPQLPTQDELKHKS
                     KPAQSFNNDVNQKDTRATSLFETDPSISNNDDSGQFNVVDSKDTRQFVKSIAKDAHRI
                     GQDNDIYASVMIAQAILESDSGRSALAKSPNHNLFGIKGAFEGNSVPFNTLEADGNKL
                     YSINAGFRKYPSTKESLKDYSDLIKNGIDGNRTIYKPTWKSEADSYKDATSHLSKTYA
                     TDPNYAKKLNSIIKHYQLTQFDDERMPDLDKYERSIKDYDDSSDEFKPFREVSDSMPY
                     PHGQCTWYVYNRMKQFGTSISGDLGDAHNWNNRAQYRDYQVSHTPKRHAAVVFEAGQF
                     GADQHYGHVAFVEKVNSDGSIVISESNVKGLGIISHRTINAAAAEELSYITGK"
     gene            complement(11932..12492)
                     /locus_tag="RFE25_001450"
     CDS             complement(11932..12492)
                     /locus_tag="RFE25_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDU2816519.1"
                     /translation="MSRKTALLVLDMQEGIASSVPRIKNIIKANQRAIEAARQHRIPV
                     IFIRLVLDKHFNDVSSSNKVFSTIKAQGYAITEADASTRILEDLAPLEDEPIISKRRF
                     SAFTGSYLEVYLRANDINHLVLTGVSTSGAVLSTALESVDKDYYITVLEDAVGDRSDD
                     KHDFIIEQILSRSCDIESVESWKSSL"
     gene            complement(12661..14568)
                     /gene="sasF"
                     /locus_tag="RFE25_001451"
     CDS             complement(12661..14568)
                     /gene="sasF"
                     /locus_tag="RFE25_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-wall-anchored protein SasF"
                     /protein_id="HDU2816520.1"
                     /translation="MAKYRGKPFQLYVKLSCSTMMASSIILTNILPYDAQAASEKDTE
                     ISKEILSKQDLLDKVDKAIRQIEQLKQLSASSKAHYKAQLNEAKTASQIDEIIKRANE
                     LDSKENKSSHTEMNGQSDIDSKLDQLLKDLNEVSSNVDRGQQSGEDDLNAMKNDMSQT
                     ATTKYGEKDDKNDEAMVNKALEDLDHLNQQIHKSKDALKDASKDPAVSTTDSNHEVAK
                     TPNNDGSGHVVLNKFLSNEENQSHSNQLTDKLQGSDKINHAMIEKLAKSNASTQHYTY
                     HKLNTLQSLDQRIANTQLPKNQKSDLMSEVNKTKERIKSQRNIILEELARTDDKKYAT
                     QSILESIFNKDEADKILKDIRVDGKTDQQIADQITRHIDQLSLTTSDDLLTSLIDQSQ
                     DKSLLISQILQTKLGKAEADKLAKDWTNKGLSNRQIVDQLKKHFASTGDTSSDDILKA
                     ILNNAKDKKQAIETILATRIERQKAKLLADLITKIETDQNKIFNLVKSALNGKADDLL
                     NLQKRLNQTKKDIDYILSPIVNRPSLLDRLNKNGKTTDLNKLANLMNQGSNLLDSIPD
                     IPTPKPEKTLTLGKGNGLLSGLLNADGNVSLPKAGETIKEHWLPISVIVGAMGVLMIW
                     LSRRNKLKNKA"
     gene            complement(14809..16167)
                     /gene="gtfB"
                     /locus_tag="RFE25_001452"
     CDS             complement(14809..16167)
                     /gene="gtfB"
                     /locus_tag="RFE25_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HDU2816521.1"
                     /translation="MIKLFDYFNDHSRKLYESFKASKLEEDLTIVLNDNGFLPDDVIS
                     PYQFFADNHNTENMKPRFFNQVTVPAFWEIKGNNNSATINDMGRLRGKIFYQSGERPR
                     IVSRVEWFDDQQRVRFVDYYSKNGIKFAQTVYDLNRKAILKKYMTAEGKEVIYENFVT
                     SDVILDWQGKSYFFPSKLAFVLFFIKQLEITEHHFVINSLALPFSVLYNLPSKGSDVL
                     VWQEHCNGNVPGNMQLMCKGDMKRHCNIIIPDKNEYETMLNIADAKVQSRILQGGYLY
                     NYRSRNRYTKEIVILTNSDQLRNIKVLVETLPDFNFHIAAITEMSDKLMQLDQYANVH
                     LYPSINIDRVNELYQLCDIYLDINEGNEILNAVEQAFDYELLILGYRQTAHHAKVTLS
                     EHLFEHNDEITMESKDQLIQMLESLKDQQQFRDALLAQKAHAHEISREQFEQVFKQAL
                     ES"
     gene            complement(16160..17668)
                     /gene="gtfA"
                     /locus_tag="RFE25_001453"
     CDS             complement(16160..17668)
                     /gene="gtfA"
                     /locus_tag="RFE25_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HDU2816522.1"
                     /translation="MTIYNINFGIGWASSGVEYAQAYRAKLLRRTNQDTKFVFLDFIQ
                     SENIQTLTQNIGFKDQEVIWLYQYFSDISIAPTTYTLDDIERELGHEISFRERNGKIV
                     RLYFNGKSSFVTCYLQNEQKDVVDRAEFVINSMLVRKDFYSYTRIFSEYYAPADNKAK
                     LYMRQFYNEDGSIAYNEYIDGDSSIYVFEDAVLYNKTEFIAYFLQRLNLTRDDIVILD
                     RASDIGQAVLQHKGDSKVGVVIHADHYSNNMMSEQHILWNNYYEYQFSKAKYIDFFIT
                     ATDIQNHMVCRQFEQYQGYRPRVYTIPVGSIDALSYPKLSRKPYAMISASRLANEKHI
                     DWLVKAVIVAKRQVPELTFDIYGEGSEKTRLRKIIDTHRAQDYIRLLGHVKLDEIYND
                     YELFLSASTSEGFGLTLMEAVGSGLGMIGLNVNYGNPTFIRDGENGYLVPFDTDEDSV
                     DDVIAKLAHAIVMYFNNGPQAPHDISYEVAQQFMTQDIILKWETLVQEVLHD"
     gene            complement(17686..20076)
                     /gene="secA2"
                     /locus_tag="RFE25_001454"
     CDS             complement(17686..20076)
                     /gene="secA2"
                     /locus_tag="RFE25_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HDU2816523.1"
                     /translation="MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTI
                     EFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTG
                     EGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVD
                     YEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIIL
                     DAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSY
                     FNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQ
                     AGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKI
                     VVQAPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFS
                     KVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGG
                     LAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYS
                     LDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNR
                     VLEIDDAENRDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKD
                     KQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKAS
                     VNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP"
     gene            complement(20066..21025)
                     /gene="asp3"
                     /locus_tag="RFE25_001455"
     CDS             complement(20066..21025)
                     /gene="asp3"
                     /locus_tag="RFE25_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HDU2816524.1"
                     /translation="MLKNKTFKVTWNYISQTTFMYGSKVSFSNGEVTFINPLMPSGLP
                     IHEWLMLKQFSKYKSAPSLPILRRGQHYKLHFDFDATPAGSVYFIIIFYNKNGTKLST
                     EIVKSNSITIQYPDEAYAYKIKMMNAASTSLIFRCLTITEMTHQDDLEYKSMRVTKID
                     DNQYGNDRINVIIAEPSDTYPTISNDFLKLFGHVWLVERWMDDDIKENIKQLKDDLQS
                     QDTLTAINLISYGSKSNVFATYVAQHLDCKVYRTSHEDDDLKEWLTEHVPGNNELKDT
                     NVEFYFKEEQDNHLNYMSRLMNPVRFLDYLDVSKLNGGEVNET"
     gene            complement(21003..22571)
                     /gene="asp2"
                     /locus_tag="RFE25_001456"
     CDS             complement(21003..22571)
                     /gene="asp2"
                     /locus_tag="RFE25_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HDU2816525.1"
                     /translation="MPRKFRVLQIGGDDLEPIFQHKKGVSWDYFDIGLFEFDSGYVEA
                     IEAIVEAEGRFDFIYIQAPYSETLTNLLQMISEPYNTYVDESFWSVEYEQDENVQKYV
                     VQPLHYRNIEERNNKLEAVSFSGQYGDKVSPKLALVHPNFKVDVVYQGNSELTLSGEF
                     GKEFKPIASWQNNLVYDKDKVIQIWPEFDIDGAVELQYTFRLIQTGADGALIEQIILT
                     DDMLDSPLEIPAKPFDAYISVTVKARGNGTVHLGPIHKRWSRLDMGQFLLGGSRFVDS
                     QRQEFIYYFHPGDMKPPLNVYFSGYRTAEGFEGYYMMKRMNAPFLLIGDPRVEGGSFY
                     IGSSEYEQGIINVIDETLEKLNFKSHELILSGLSMGSFGALYYGAQLNPQAIIVGKPL
                     VNIGTIAEHMRLLRPEEFGTALDVLVSNEGDTSQASIKALNQKFWQTFQKKSLSQTVF
                     AIAYMQHDDYDPHAFQELLPVLTAHQARVMNRSIPGRHNDDSPTIASWFVNFYNIILE
                     DKFGRVQHAEKQNI"
     gene            complement(22561..24114)
                     /gene="asp1"
                     /locus_tag="RFE25_001457"
     CDS             complement(22561..24114)
                     /gene="asp1"
                     /locus_tag="RFE25_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HDU2816526.1"
                     /translation="MKYFIPAWYDDQRWWQDTTVPYYQLQNKTEFDDMISLMGMHLEN
                     DLDYQLIVLNHAPNLRTFLHRYDLYETKYSSVFDEIQGFSHHAPQAINYHHLKWPDDV
                     EFVYTPYLLKCVTSEQTYTNIYFSQEGYSIWFEEFERDQLQRRYIFDDRGYLSAIRYF
                     DDQGEASYQQYLTINGDCVLHEDLKNGRVTVSKRYQHHYQQTEYNNMAQLIEEKFQAM
                     IAQQIHEDDHVIVASDARHNRQIANHIPAKLLSYSFFKNRNETVSDEEYQSIVKNAHL
                     IVDSVQLERDLISHQEKYQRENTMIRITPFETRQSPNISSQLMETFIGVWIDGMSDAD
                     LQQMMQRLVDYIAQEDYYRLILLSRHQNDIPMWLRECITSVNEEYQAKQNADVNVSAL
                     MTPEDQDDIIAVKTIHAEHDVVEALRTLRLVIDMSKEPDLYLQISAISAGIPQINGQQ
                     TDYVSDYDNGRIINTVDELDDALNYYLFYLKNWNYAYAYSLKLIDAYASKNIINQLDE
                     LIEGENDAT"
     gene            complement(24125..25336)
                     /gene="secY2"
                     /locus_tag="RFE25_001458"
     CDS             complement(24125..25336)
                     /gene="secY2"
                     /locus_tag="RFE25_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HDU2816527.1"
                     /translation="MLKLLQQYEYKIIYKRMLYTCFILFIYILGTNISIVSYNDMQVK
                     HESFFKIAISNMGGDVNTLNIFTLGLVPWLTSMIILMLISYRNMDKYMKQTSLEKHYK
                     ERILTLILSVIQSYFVIHEYVSKERVHQDNIYLTILILVTGTILLVWLADKNSRYGIA
                     GPMPIVMVSIIKSMMHQKMEYIDASHIVIALLIILVIITLFILLFIELVEVRIPYIDL
                     MNVSATNMKSYLSWKVNPAGSITLMMSISAFVFLKSGIHFILSMFNKSISDDMPMLTF
                     DSPVGISVYLVIQMLLGYFLSRFLINTKQKSKDFLKSGNYFSGVKPGKDTERYLNYQA
                     RRVCWFGSALVTVIIGIPLYFTLFVPHLSTEIYFSVQLIVLVYISINIAETIRTYLYF
                     DKYKPFLNQYW"
     gene            complement(25466..32281)
                     /gene="sasA"
                     /locus_tag="RFE25_001459"
     CDS             complement(25466..32281)
                     /gene="sasA"
                     /locus_tag="RFE25_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-rich repeat glycoprotein adhesin SasA"
                     /protein_id="HDU2816528.1"
                     /translation="MSKRQKAFHDSLANEKTRVRLYKSGKNWVKSGIKEIEMFKIMGL
                     PFISHSLVSQDNQSISKKMTGYGLKTTAVIGGAFTVNMLHDQQAFAASDAPLTSELNT
                     QSETVGNQNSTTIEASTSTADSTSVTKNSSSVQTSNSDTVSSEKSEKVTSTTNSTSNQ
                     QEKLTSTSESTSSKNTTSSSDTKSVASTSSTEQPINTSTNQSTASNNTSQSTTPSSVN
                     LNKTSTTSTSTAPVKLRTFSRLAMSTFASAATTTAVTANTITVNKDNLKQYMTTSGNA
                     TYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGF
                     AFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAF
                     GAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQT
                     WTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGK
                     DIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQS
                     VTYYFTDVKAPTVTVGNQTIEVGKTMNPVVLTTTDNGTGTVTNTVTGLPSGLSYDSAT
                     NSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPIS
                     PIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKT
                     TTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKS
                     TSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNS
                     NSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDS
                     TSNAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTS
                     ESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDSKSMS
                     VSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSLSTSQSGSTSTSTSTSASVRTSESQS
                     TSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTS
                     NSERTSTSVSDSTSLSTSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSES
                     QSASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASIS
                     TSTSISESTSTFKSESVSTSLSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMSTS
                     DSISTSKSDSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTS
                     TSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQS
                     ESTSTSTSLSDSTSISKSTSQSGSTSTSASLSGSESESDSQSISTSASESTSESASTS
                     LSDSTSTSNSGSASTSTSLSNSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLS
                     DSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGS
                     ASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDS
                     TSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDS
                     KSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSGSQSMSDSVSTSDSSSLSVSTSLR
                     SSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTS
                     TSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNS
                     QFDSMSISASESDSMSTSDSSNISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGS
                     TSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMSASTSSSQSTSVSTS
                     LSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDSTSTSTSDSTSGS
                     TSTSISESLSTSGSGSTSVSDSTSMSESDSTSVSMSQDKSDSTSISDSESVSTSTSTS
                     LSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTSTSESNSMHPSDSMSMHHTHSTS
                     TSRLSSEATTSTSESQSTLSATSEVTKHNGTPAQSEKRLPDTGDSIKQNGLLGGVMTL
                     LVGLGLMKRKKKKDENDQDDSQA"
BASE COUNT        10073 a         6051 c         5119 g        11352 t
ORIGIN      
        1 aatcaatgct tgaaatatgt gagataacta tttaaataat catgatcaaa taaacatttt
       61 tatcaatttc aaacaactat gtaagacgca ataatcgtta ttatttaata aaaaagacta
      121 gaatgcggta tctctcctca cactctagcc ttaatatgcc attattttat ttacttgttt
      181 tgtatggtgt atgtccaact gttacttcga caactctatt atgatcaacg acaaaccaga
      241 tgcctaatgt ctttttagca ttttgatagt aaaaaatacc gctatcagct tcctttgttt
      301 taccattttc ttttttcaag tccttgccat aagctttttg gatatctttt aatgaaatat
      361 tatttttaac tacaaattgc aattgacttg cttcgtttcc ttttgcagaa acacctttaa
      421 aagtttgatc atatttctct acttttttta tcgtattcgt tttagctaat ttaataccat
      481 tgaatttcac attatcatac ttaatcgcgt taataaaatt cttatccaga ataaaattag
      541 cattattacc aatataacca ttataagtat aatatggggt tattgctgcc tgtgcctgtt
      601 tacttgttgg cgccgaattt tcaacaactg ttactccaat cagtgtgccc aatgctaatg
      661 ttgctgctac acaaacttta ctggttttat tcataattat ctctcttttc catacaaata
      721 ttttattcct tacactttta ttataacttt ttcagccata aaaatactaa tgattatatt
      781 tataaataca taacagtttt gttatactaa ttgaagtaca caaaaaacaa tgaaaatatt
      841 aatatcgcct acttttctaa tatttatttt ttaaaatgat tatggcaata ttgaaataaa
      901 ttatttagct tcacgtatca actacttttc attaacatgg aggcgttata tttgaaaaaa
      961 cttcttatta ccatcgtaat tatcgtatta atcggagcac ttgggttcgc aatttatgct
     1021 gcaataaatc attctacatc atcaagtaat aaccaagaac aagaaaataa atctacgcat
     1081 aaaaaaacag aaaccgaaga aaatgatcaa caagatgata gtgcagacaa aacagataaa
     1141 aatcaaaata atggcaataa cgatactaat gacaatcaac catcttcacc gtcaaatgtt
     1201 cctaacaacc attcaacagt accatcgaat acgcaaccag ctcagccaaa agactcaaat
     1261 tcaaataaaa ataatactca cggtggtggc agtcaatcgt caacaaacaa ccaaaataat
     1321 caacaacaga acacaccacc tgctaataaa tcaaataata ccaatacgcc ttctaaacaa
     1381 acacctcaag cacaatcacc taaaaattaa tcatttgcct gatacgtcca caagtaccag
     1441 atgcataaat tcagaaaaac agcagtgaga tatttttcta tttgaaatat cttactgctg
     1501 ttctttattt gcataattcg cactctgtta aaatcatata aaagttcgct ttaatgtcat
     1561 tgacgtatgt ataagctctc atgtttaata atattaatac acctttaaaa acgcttacac
     1621 gaaaaattta gaaaggaggt acatgttaaa tgcttgatag acacttaaaa ctactccagt
     1681 tttttattaa aaatccatca aagcacatta gttctaatga aattgctgaa catgtcaatg
     1741 tttcaaaccg cacagttcgc aatgatattc atgttatcaa tagcaatttt atggatgata
     1801 tcatcgtaag tattaaatct aaaggatatc aattaaatac atcgcagtat accttagaaa
     1861 cgataactga acgttacacg catattcaat catataaaga aaaactatta ttatctatgg
     1921 cgtatcaact gctaatgcac aataaatcgc agacattgca acaactagag caagattatc
     1981 tattatctaa aactgtgctc aacgactatt tcgttcgaat tcaacaatgg tgtcaaaaat
     2041 ttaatatcgt tttaacaatc aagaaaaaac aaggtattgt ggtcgatgga acagataatg
     2101 atatcactaa tgccatcatc catttaaatc aattatcatc agggcatgta catgttgaag
     2161 acctaatttt aaatgaatta cctgattcac accaaaggat gatttcgcat attatacaag
     2221 agacacttca acaacatagt attgaaacaa ctgatattca aatacaacag cttttaattc
     2281 atctcatttt aatcattaaa cgtaagcaat ctttaagtga gctagacacg ttaaaccatg
     2341 atgcaaaatt gatatctcaa tcttgcatta agcaaatcaa cgaaagatta ggttatgact
     2401 tgaacgaaaa agtaatcaat atgttttcat tctttattgc ttatcatttt aataaactcg
     2461 atattgttat agaacgtata tttatacaaa gttatattga tcgcttaatc gaattgatgc
     2521 agcaacgtat tcatgtacct ttcaatgaag attcgatttt acaacaaaat ttatataatc
     2581 attttagtaa agcatattta cgtatcactc aaaacattta tttaaacaat cctttagtta
     2641 tagagattaa aaaactctat ccctttgtgt ttaacacact ttttgaagcg attgataaat
     2701 tagcaattga tactgatata gagatgagcg aagatgaaat tgcattttta acaattcatt
     2761 ttcaagctgc catcgagcgt cgtaccaaaa cacaattaaa tgtagtcatt gcttgttatt
     2821 atggtctagg tgtgtcgaat tttttagaaa ctaaaataaa taacttatcc gaagagttgt
     2881 cagtaataaa tacgattaaa ctagaaagta taacacacta tcactttgac aatgtagatt
     2941 tattaataac gacccatgat attccaaaac aaacgctaaa catacttcct aagcacctga
     3001 cgactatcaa ggttgcacca ttattttctg aagatgatcg tcacaaaatc agacacgttg
     3061 tgaagcaaaa gcaaaatccg gttcaagcac atcatcatat ggacactgtc aatttccttg
     3121 tcgtaaatac tgaacaaaaa tcacggcata ctgtgcaaat ttttgaagaa gctcaaaaaa
     3181 tattacaagc acatcatgcg attgtagaag gatatatcga atcagcttta gagcgtgaga
     3241 aatcatcttc tacatacata ggtaatttta tggcgattcc tcatggagat cctgaaaaag
     3301 ttttacaatc acatgtgctt atttttcgca caaaagatgt ttttccttgg cgacaacacg
     3361 atgtcaaact tgtctttttc ttagcgattt cgcataaaga caaagctttt acaaaacaaa
     3421 tgatgcaatt aattgctaac ttggatgatg attcagtgaa ccatttatgt agtttagatg
     3481 atcatagttt aaagcaacag ttatttgaat acttacaaga ataattgcca ctagtaacgg
     3541 taattattct ttttttagta tcgagaatac gcttacaata tagaaaagga gatgatttta
     3601 tgaaaattgt agctattacc tcatgcccaa atggcattgc acatacatat atggctcaag
     3661 aaaagcttga gcaggtagca aaagaaatgg gtgtggatat taaagtagag acacagggcg
     3721 gtgttggtgc tgaaaatgtt ttaactacgc aagacatcga agaagctgac ggtgtcataa
     3781 ttgcagctga taaacaagtt gatctatccc gatttgttgg taaacggttg attaatgaaa
     3841 atgttcgcga agggattcat aatccgagag gtctaattca acgtatcatt aatcaagatg
     3901 cgcctattta tcaatctgaa acaaattatc attcgaaaga tcgcggtaag tctaaaagtg
     3961 gtattcaaat ggtgtatcaa catttaatga acggtgtatc gtttatggtt ccttttatcg
     4021 tagttggtgg actccttatc gccatcgcgc tgactctagg cggtgaaacg acatcaaaag
     4081 gattagtcat cccagatgat tcattttgga aatccattga aaacattggt agtttagcct
     4141 ttaaatttat ggttccaata ctagctggat atatcgctgt tagtatcgct gacaagcccg
     4201 gtcttgttcc tggtatgatt ggcggcgcta tcgctgctga cggtagtttt tatggcagtg
     4261 atgcaggcgc aggattttta ggtggtattg ttgctggttt cttagcaggt tatatcgcaa
     4321 agtggattaa agatattaaa gttccaaaag caatggcacc aattatgcct atcattatta
     4381 ttcccattat ttcatcggtc gttgtaggat tgatatttat atttttaatc ggtgcaccaa
     4441 tttctaatat ttttgaggca ttaacaacct ggttaaaaag tatgcaaggt gctaatatta
     4501 ttatacttgc gatgattata ggtgcgatga tcgccttcga tatgggcggt ccagtaaaca
     4561 aggtagcatt tttatttggc tcagcactta ttgctgaagg taattacgcc gttatgggta
     4621 tggtcgcagt tgctgtatgt acaccaccaa tcggtttagg tttagcaacg tttgttcaaa
     4681 agtataaatt caatcattcc gaaagagaaa tgggtaaggc ttccttcact atgggactat
     4741 ttggtattac tgaaggtgct attcctttcg cagcccaaga tccattgcgc attatacctg
     4801 caaacatcat tggtgcaatg attgcatcag tcattgcagc cattggtggt gtcggcgata
     4861 gagtcgcaca tggaggtcca atcgtggctg tattaggtgg tattgatcat gtattatggt
     4921 ttatctttgc agtgatagta ggtagtcttg tcacaatgac tactgtacta ttattaaaac
     4981 gcaatacacc agttatagca gtagatgcac cagcgcaaca cacgcaactt catgatacag
     5041 atattacaca acatgataca gaggttgaca atgtagataa aaccgcgaaa cattcacatc
     5101 tcaataaacc ttctcatgtt tttgatcaac aaactatgat aattactgat cacgacatgt
     5161 ctcgaaacga agcaattgat atgttgattc ataaacttaa aatttgccgt tatgtagagc
     5221 acacatcgca tttaaaaaat gcaatactag aacgtgaaat ggagtctacg acagctattg
     5281 gcatgaacgt ggccattcca catgcaaagt ctgatgttgt aaaacaaccg attgtagctg
     5341 ttatgaaaaa taatcatggt gttaaatggg acagtctaga tggtagtcta cctcaattga
     5401 tattcttaat tgccgtacca aacaacagtc aggatacaca tttaaaaata cttcagcgct
     5461 tatctaaagc gttaatgaat gatgagacac gccaatcact aattaatgca aacagtacta
     5521 cagaaattta taacttatta atgaaaatat agaggagttt taactatggc attattttta
     5581 caacccgttt ttaaagacag aatttggggc ggtcatgcat taaaagcatt taactatgat
     5641 atccctaatg aaacaactgg tgaatgctgg gcaatttctg cacatccaaa tggtcctaat
     5701 acaattatca atggtccata caaggatatg accctagatc aactttggtc acaacatcgt
     5761 gaattattcg ataatgattc acgagatagt ttccctctgc taactaaagt attagatgcc
     5821 aatgataaat tatctgttca agttcatcca gatgatgact acgctttaaa acacgaaggc
     5881 gaactaggta aaacagaatg ttggtatatt ttagatgcag ccccaggtgc tgaaattata
     5941 tatggcgtac atgcacataa taaacagacg ttaatcgaca tgattgataa tcatgaattt
     6001 gacagtcttt tcaaacgtat acctgttaag cccggtgact tttattatgt tcctgctggc
     6061 actgtccatg ccattggttc gggtatttta attttagaga cacaacaatc atccgatacg
     6121 acataccgta tttatgacta tgatagacga gatcaaaatg gtcaattgcg tgatttgcac
     6181 ttagagcaaa gtaaagatgt gattgaatta ggcaatcatg aaccaaatac tactcctata
     6241 acaactcaca tcgacacaca cactgtaact caatttgtag ataatcaata ttttgcagta
     6301 tataaatggg atattcatgg agatttaaaa ttcaataaac cacatgctta ttgcttagtt
     6361 actattatcg atggtactgg tactttaaca gtaaacgata agcactatga catccaaaaa
     6421 ggttctagct ttattttaac tacggaagac gaggatattc actttgtcgg taatattagt
     6481 gctatagtaa gtcatcctgg ataatagcaa tgataacaac cgtcccataa aagacagaaa
     6541 ttactatctc ttctgtctaa aaacataaaa atccacacat taaggagcta taaccctaat
     6601 gtgtggattt aatttttatt ctgtaacgtt actttggtca actttttcag atacgcgctt
     6661 catcaatgga tctgttacag gttttaaaat taaacctaca acgaagaatc ctatgccaaa
     6721 taacgttaat ataattaatt ttgtaattag gatttccgga acaataccgc ctactgtttc
     6781 acgtaatgaa tcaattgcat acgtaaatgg taagtatggc gaaatgtttt ggaaaaattg
     6841 tggcgtagtt tgaattggga atgttcctcc accacctgca atttgtaata caagcaatac
     6901 gattgcaatt gctttacctg ggttaccaag taatgatacg cacgtatata cgattgagtt
     6961 gaaaataatc gaacagaaaa tcgttataag tacaaataat acaggtgact caactcctgc
     7021 ttttaggatt aacaaatctc caaccgatac aatgagtgct tgcaacatac caagcattat
     7081 aaagaatcct gccttaccta agaacacttg tcttgtcgtt aagactgact ctagactctt
     7141 atgtttatta tcaaccgtta ataaacttac catcaagagt gcacctaccc atactgacag
     7201 tgcagtatag aatggtgtca tacctgaacc ataatcctta actgggaaaa catcaacagt
     7261 cttcttatta ataggatttg caataatacc cgcttgcttt ttcaaatcat tcttaagtgt
     7321 gtcgattaat ttgtcgactg catcatcttt gtctaatttc ttgaaaattt tattcgcttt
     7381 tttcaaatct ttttcaacat caggcaattt attttgagaa aaatcagcta aatctgataa
     7441 agcctttttc gcttgtggct gatttttatt tagtaatcct accgcttgat cataaccatt
     7501 taataacgtt ggtaaatttt tattcacact tgctgtcgca ttagttaatc gctgttccaa
     7561 ctgtggtaag tcattgcgca caaagttagc agctttagct acatcacttt tcactttcgg
     7621 gaagtttgct tgagcatttt taacagcact aatgtattgt tgttcaatac ttggtaatac
     7681 tgtttgtaag cgatcaatac gtgttttacc attttttaaa atagcttgtc cactgttaat
     7741 gacttgatca attgtattta atttagactg aacattggat aatgcagttt gccctttgtt
     7801 caattcatcc ataatacgtt gtgatattga tactaaagag ctgttaagat cttttttaac
     7861 ataatctcta aatgatgata atgatgaatc tagttttgaa agttgatcta gtaatttagt
     7921 agcttcagca gttcctgaac taccattctt taatgcattg cttaattgat taactaacct
     7981 taatgattca ttaattcgat tattagctgc ttttacctta tcaatttctt ttgataaatc
     8041 aacattttca ttcttctcaa tctcttttaa tgtatcgata aattgttgat tatattgcgt
     8101 tgtgtattct aaaccggact taacattatc taaagactct ctaaaatcag aaggcttgtc
     8161 cgatgctaaa atgccatacg aaatattacg taatgcctga ctatcttttt gtgcggcttt
     8221 cgcttgggta tctaaattat ttgataatga taataaagag cccgttaatg ccgcttccat
     8281 tgatttaaca tctttatctg taatgttttg tgtgttctcg ttagctgtgc tgacttgtgt
     8341 tgttgttata tctgcaaaac tttgaccatc ttttttcccg cttgtacttt gtggtgtagt
     8401 cgatacaggc gcattattac tatttggtgc ggtattttgc gtaacattat tatttggtgc
     8461 agtatcgcca cttggtgcac ttggtggcgt tgatgctaca ccattaccag ctgcaggtga
     8521 actatttgat gtttcgttgt tcgccgcgct attttgagga atctgttgct ggtttcttcg
     8581 atttaaatct tgcgcgcgtc gaattgcatc ttgataatca ccgactctac ttctaacttg
     8641 tgtgacgaag cctttggcat catttaactg tccattagct tgatcaatcc cttgactcgc
     8701 aatgttaagt ccttgattaa ttttagggaa ctgcgctggc acgtcatcag ctgcaaaatt
     8761 taacgctttt tcaattttcg gcatataatt atttaaagct aatatcaact tagccttttc
     8821 attaagttgc ggaatagcac cattgacttc gtttaatttt ttctgagcat ctaaaatatc
     8881 acctttataa tttcctagtt ttctaaaatc attggcatat ttatctaaat ccgcttggtg
     8941 gttattcaaa tacacaattt tattcgcaaa gtcattaatc ttaggtaaag ctttatctgc
     9001 tgaatatacc gcatttttta tcttgttaat tgtcggcaca ttttcttcaa tagttaaacc
     9061 tgctttgtta gcttcttcta ataatgctcg agttactgtt ttattaaatt gttcattcgc
     9121 tttttcaacg acaactgacg aaccagtatc tgttagctta gacgcaacag cgttaatctt
     9181 ctgattcacc ttaaattcta catctgcttt ttgaggctgc ttacgtagtg tcccggtaat
     9241 ttcatgtgta aacttagatg ggatgtaaat acctgcaaaa tatttaccca tttttatctc
     9301 atgatcagct ttctctctac ttacaaactg ccaatcaaaa cttttatttt tcttgagtgt
     9361 attaaccatc gtattaccga cattaacttt tttccctctg attgtgtcgc ctttatcttc
     9421 attaacgact gcgaccttga tgtgtcccgt gttgccatat ggatcccaca ttgcccataa
     9481 gttaaaccaa gcgtagaacg atggcaaaat agctaagcct gctaagataa tccacacagc
     9541 tggcgtctta gctactttct tcagatccat tttaaataat ttaaatgcgt tcttcattgt
     9601 cacactccta tgtaggaatt attcatattt tttatatatt ttttgtaaat taatttattt
     9661 ttgcgttgtg aattagtata atcaatttac tggaagatat ttagtcgatt gatacctatc
     9721 aactattttc agcatacgat aaattataac aaatcatagt ttattatcac acttaattat
     9781 tatatttttc aagggagaat acgaaatatg cctaaaaata aaattttaat ttatttgcta
     9841 tcaactacgc tcgtattacc tactttagtt tcacctaccg cttatgctga tacacctcaa
     9901 aaagatacta cagctaagac aacatctcat gattcaaaaa aatctaatga cgatgaaact
     9961 tctaaggata ctacaagtaa agatactgat aaagcagaca acaataatac aagtaaccaa
    10021 gacaataacg acaaaaaatt taaaactata gacgacagca cttcagactc taacaatatc
    10081 attgatttta tttataagaa tttaccacaa accaatataa accaattgct aaccaaaaat
    10141 aaatacgatg ataattactc attaacaact ttaatccaaa acttattcaa tttaaattcg
    10201 gatatttctg attacgaaca acctcgtaat ggcgaaaagt caacaaatga ttcgaataaa
    10261 aacagtgaca atagcatcaa aaatgacact gatacgcaat catctaaaca agataaagca
    10321 gacaatcaaa aagcacctaa atcaaacaat acaaaaccaa gtacatctaa taagcaacca
    10381 aattcgccaa agccaacaca acctaatcaa tcaaatagtc aaccagcaag tgacgataaa
    10441 gcaaatcaaa aatcttcatc gaaagataat caatcaatgt cagattcggc tttagactct
    10501 attttggatc aatacagtga agatgcaaag aaaacacaaa aagattatgc atctcaatct
    10561 aaaaaagaca aaaatgaaaa atctaataca aagaatccac agttaccaac acaagatgaa
    10621 ttgaaacata aatctaaacc tgctcaatca ttcaataacg atgttaatca aaaggataca
    10681 cgtgcaacat cattattcga aacagatcct agtatatcta acaatgatga tagcggacaa
    10741 tttaacgttg ttgactcaaa agatacacgt caatttgtca aatcaattgc taaagatgca
    10801 catcgcattg gtcaagataa cgatatttat gcgtctgtca tgattgccca agcaatctta
    10861 gaatctgact caggtcgtag tgctttagct aagtcaccaa accataattt attcggtatc
    10921 aaaggtgctt ttgaagggaa ttctgttcct tttaacacat tagaagctga tggtaataaa
    10981 ttgtatagta ttaatgctgg attccgaaaa tatccaagca cgaaagaatc actaaaagat
    11041 tactctgacc ttattaaaaa tggtattgat ggcaatcgaa caatttataa accaacatgg
    11101 aaatcggaag ccgattctta taaagatgca acatcacact tatctaaaac atatgctaca
    11161 gatccaaact atgctaaaaa attaaacagt attattaaac actatcaatt aactcagttt
    11221 gacgatgaac gcatgccaga tttagataaa tatgaacgtt ctatcaagga ttatgatgat
    11281 tcatcagatg aattcaaacc tttccgcgag gtatctgata gtatgccata tccacatggc
    11341 caatgtactt ggtacgtata taaccgtatg aaacaatttg gtacatctat ctcaggtgat
    11401 ttaggtgatg cacataattg gaataatcga gctcaatacc gtgattatca agtaagtcat
    11461 acaccaaaac gtcatgctgc tgttgtattt gaggctggac aatttggtgc agatcaacat
    11521 tacggtcatg tagcatttgt tgaaaaagtt aacagtgatg gttctatcgt tatttcagaa
    11581 tccaatgtta aaggattagg tatcatttct catagaacta tcaatgcagc tgccgctgaa
    11641 gaattatcat atattacagg taaataagta ttattaaacc cgcaaaattt ataagtataa
    11701 acaaggagtt cggacttaaa catatttctg ttcataagtc cgatttctta ttcaattaaa
    11761 cccgaggtat tcagttcgaa cgcctcgggt cattttatat aaatatatta ttttatgttc
    11821 aaatgttcct catcatatcc gtttcaattg tcatctcaca cattttataa atatgagcaa
    11881 atgtacttat tttcaaacat tactgcctag ctttaattga cgttatatta actataaact
    11941 acttttccat gactctacgg attcaatgtc acatgagcgt gataaaattt gttcaataat
    12001 aaagtcatgt ttatcatctg atctatcacc aacagcatct tctaaaacag taatataata
    12061 gtctttatct acactttcta atgccgtgct caatacagct ccactcgtag agacacccgt
    12121 taatactaaa tgattaatat catttgcacg taaataaact tccaagtaac tacctgtaaa
    12181 tgcgctaaag cgtcgcttag aaataatcgg ctcatcttct agtggtgcta aatcttcaag
    12241 tattcgtgta gatgcatctg cttcagtaat cgcatatcct tgagctttaa ttgttgaaaa
    12301 cactttatta ctcgaggaga catcattaaa atgcttatct aacactaaac gtatgaaaat
    12361 gactggtatt cgatgttgtc ttgctgcttc aattgctctc tgattcgctt taataatatt
    12421 ttttattcta ggtacactac tcgctatacc ttcttgcata tccaaaacta atagcgccgt
    12481 ttttcgagac atcttcattc tcctttactt ctgtagttct aagtcgttaa attcattata
    12541 acgttaaaat gatggacaat ctattcattg cattttgcat atacttcaca ataatttaag
    12601 ggggaaataa gacgtcttat atacttaaaa aaatatatag atgctcttcc cccaatataa
    12661 ttatgcttta tttttcaact tattgcgtcg tgataaccaa atcattagta cacccattgc
    12721 accaacaatt acagatatcg gcaaccaatg ttcttttatc gtttcccccg ctttaggcaa
    12781 agatacatta ccatcagcat ttaataatcc acttaacaat ccattacctt taccaagtgt
    12841 taacgtcttt tctggctttg gtgtgggtat atctggaata ctgtctaata aatttgatcc
    12901 ttgattcatt aaatttgcta acttatttaa atccgttgtt ttcccatttt tattcaatcg
    12961 atctagtaaa cttggacgat ttactattgg tgataaaata tagtctatat cttttttcgt
    13021 ttgattgagt ctcttttgta aattcaataa atcatccgct ttaccattca atgccgattt
    13081 aactaaatta aaaattttat tttgatctgt ttctatttta gtaattaaat ctgccagtaa
    13141 ttttgccttt tgtctttcta tacgtgttgc taaaatcgtt tcaattgctt gctttttatc
    13201 tttggcatta ttcaaaattg cttttaatat atcatctgaa gacgtgtcgc cagttgatgc
    13261 aaaatgtttc ttcaattggt caacgatttg gcgatttgat aatcctttat tcgtccaatc
    13321 tttagccaat ttatctgctt cagcttttcc taatttcgtt tgtaagattt gagaaatcaa
    13381 tagcgactta tcttgtgatt gatcaatcaa tgacgttaat aaatcatcac tcgttgtcag
    13441 agatagttga tcaatatgac gagtaatttg atctgcaatt tgttgatctg ttttaccatc
    13501 aacacgtata tcttttagaa ttttatctgc ctcgtcttta ttaaatatac tttctaaaat
    13561 gctttgtgta gcatactttt tatcatcagt acgtgcaagt tcttccaaaa taatatttcg
    13621 ttgacttttt atacgctctt tcgtcttatt tacttcgctc attaagtctg atttttgatt
    13681 tttaggaagt tgcgtatttg caatacgttg atctaaagat tgtaacgtat tcagtttatg
    13741 atatgtgtaa tgttgcgttg aggcattact tttagccaat ttttcaatca tagcatgatt
    13801 aattttatcg cttccttgta atttatcagt gagttgatta ctatggcttt gattctcttc
    13861 atttgaaaga aatttattta acacaacatg tccagaacca tcattatttg gcgttttagc
    13921 tacttcatga ttactatctg ttgtagacac tgccggatct ttcgatgcat ctttcaatgc
    13981 atctttcgat ttgtgtattt gctgattcaa atggtctagg tcttctaacg ccttatttac
    14041 cattgcttca tcatttttat catctttttc tccatatttt gttgtagccg tttgtgacat
    14101 atcatttttc attgcattaa gatcgtcctc gccactttgt tgacccctat caacatttga
    14161 agaaacctca tttaaatctt taagcaattg atctaattta ctgtctatat cactttgacc
    14221 gttcatttca gtgtgagaac ttttattttc tttgctatcc aactcattag ctcgttttat
    14281 gatttcatct atttgcgatg ctgttttcgc ttcatttagt tgtgctttat aatgtgcttt
    14341 agatgaagcc gataactgtt ttaattgctc aatttgacga attgctttgt caactttgtc
    14401 taataaatct tgcttagata atatctcttt tgaaatttca gtatcctttt cagatgcagc
    14461 ttgggcatcg tacggcaaga tattcgttaa aatgatactt gacgccatca ttgtcgaaca
    14521 cgataacttt acatataatt gaaacggttt ccctcgatat ttagccatca acatactcct
    14581 ttctcactta cttccttcaa agaattacat actattatat acctgtttac aagaaattta
    14641 cacttatcta tctagttatt gttgttagta attatcaact tattacttag cttatattta
    14701 agtaaacaaa aaagcatgac gtaatatcat attgtccatg tcgctaacat catattacgt
    14761 caaatctttt aaattaaatg atgctttatt ttagactgct ttttcttttt agctttcgag
    14821 cgcctgttta aaaacttgct cgaattgttc acgcgagatt tcgtgtgcat gtgctttttg
    14881 tgctaataaa gcatctcgaa actgttgttg atctttcaaa ctttctaaca tttgtattaa
    14941 ttggtcttta ctttccattg ttatctcatc attatgctca aataagtgct ctgataatgt
    15001 tactttagca tggtgtgcgg tttgacgata acctaaaatc aacaactcat agtcaaacgc
    15061 ttgttccacc gcatttaaaa tttcattacc ctcattgata tcaagataaa tatcacataa
    15121 ctggtatagt tcatttaccc tgtcaatatt aatagatggg tataagtgca cattagcata
    15181 ttgatcaagt tgcattagct tatcagacat ctctgtaata gcagcgatgt gaaaattaaa
    15241 atctggtaaa gtttcaacca ataccttgat gttacgaagt tgatccgagt tagttaatat
    15301 tacaatttct ttagtatatc tattacgact acgatagtta tatagatatc cgccttgtaa
    15361 aatacgagat tgaacctttg cgtctgctat attgagcatc gtttcatatt cgtttttatc
    15421 tggaataata atattacaat gtcgtttcat atcaccttta cacatcaatt gcatatttcc
    15481 cgggacatta ccattacagt gttcttgcca taccaaaaca tcactacctt ttgatggcaa
    15541 attatataac actgaaaatg gtagggctag tgagttaata acgaaatgat gttccgtaat
    15601 ttcaagttgc ttgataaaaa ataatacgaa tgcgagcttt gaagggaaaa agtaagactt
    15661 cccttgccaa tccaatatga catcagatgt tacaaaattt tcataaatca cttctttacc
    15721 ttctgctgtc atatatttct tcaagatcgc tttacgattt aaatcgtaaa cagtttgtgc
    15781 aaatttaata ccattcttag aataataatc gacaaatcgg acacgttgtt ggtcatcaaa
    15841 ccattcgaca cgactaacaa ttctagggcg ctctccactt tgataaaata ttttgcctcg
    15901 tagacgtccc atatcattaa ttgtagccga attgttgtta cctttaattt cccaaaaagc
    15961 tggtacagta acctgattaa aaaatcgtgg tttcatattt tctgtattat gattatctgc
    16021 aaaaaattga tacggtgata taacatcgtc cggtaaaaag ccattgtcat tgagtacaat
    16081 tgttaaatct tcttccaact tactggcttt aaaagactca tataactttc gtgaatgatc
    16141 gttaaagtaa tcaaataatt taatcatgta gcacctcttg aactaatgtt tcccatttta
    16201 aaataatatc ttgagtcata aattgctgtg ccacttcata agagatgtca tgtggtgcct
    16261 ggggaccatt gttaaaatac attacaatgg catgagctag ttttgcgata acatcatcca
    16321 cactatcttc gtcggtatca aaaggtacca agtagccatt ttccccatct cgaataaagg
    16381 ttgggttacc ataattcaca tttaatccaa tcatacctag tcctgagcct accgcttcca
    16441 ttagtgttaa cccaaaacct tcgctagttg atgcagaaag aaataactca taatcattat
    16501 aaatttcatc aagtttaaca tgccctagta aacgaatata atcttgtgcg cggtgtgtat
    16561 caataatttt acgcagtcgc gtcttctcgc taccttctcc ataaatatca aatgttaatt
    16621 ctggcacttg tcgtttagcc acgataaccg ctttgacaag ccaatcaata tgtttctcat
    16681 ttgctaaacg agatgcacta atcatcgcat atggctttct tgataattta ggatatgata
    16741 acgcatcaat gcttcccacc ggaatagtat agacacgtgg acgataacct tgatattgct
    16801 caaattgtcg acaaaccata tgattttgaa tatctgttgc tgtaataaag aaatcaatgt
    16861 atttagcttt tgaaaattga tattcataat aattgttcca tagtatatgc tgctcgctca
    16921 tcatattatt actataatga tcagcatgaa tcacaacacc aactttacta tcacctttat
    16981 gctgcaaaac agcctgacca atatcagaag cgcggtctaa tatgacaata tcgtctcggg
    17041 ttaaattcaa tcgttgtaaa aagtatgcaa taaattccgt tttgttatac aacaccgcat
    17101 cttcaaacac atatatagag ctgtctccat caatatattc gttataagcg atggaaccat
    17161 cttcattata gaattgtcgc atatataatt tcgctttatt atcagctggt gcataatact
    17221 cagaaaatat acgcgtataa ctataaaaat ctttacgtac taacatacta ttaattacaa
    17281 attctgcacg atccacaaca tctttttgtt cattttgtag ataacatgtt acaaatgatg
    17341 atttcccatt aaaatataga cggactatct taccatttct ttctctaaaa ctaatttcat
    17401 gaccaagctc acgttcaatg tcatctaacg tgtacgttgt tggtgctata gaaatatcac
    17461 taaaatactg atacaaccaa ataacttctt gatctttaaa cccaatgttt tgcgttaatg
    17521 tctgtatgtt ctctgactgt ataaaatcta aaaacacaaa tttagtgtct tgatttgtac
    17581 gtctcaataa tttagcacgg taagcttgtg catattcaac accgctactc gcccagccta
    17641 taccaaagtt tatattatat attgtcatgc gctacccctt ttcatttatg gaaaatgtat
    17701 aactggcata ccctctttat caaatgtaat catgctttga caaatatttt tcaccattct
    17761 ttttttgata tttcgtgtca taacttcaaa tgaatctaat gcaactctat ggtattcaaa
    17821 aatagcgtta cgttgcccat tttgtcgttg attaacgctt gcttttaatt gttgtaaata
    17881 gtcgacttgt tctaaccaac atgaatcaat tgctttcaaa aagacttttt gaacgaaaat
    17941 attataataa tatgcacttt gcatgttttt acgattcaaa gctaattgct tttcaaattg
    18001 ctctaataaa aatgtcacta ctgcttgctt atctttaaaa ttaacacaag ccacatcttt
    18061 attaaattgg aaacttaaat tttgataaat atactcgaca acacgcgatt ttgttagcac
    18121 cttttcctca tttacaaaca tttcaaatac atctttagct aacgctttaa aatctcgatt
    18181 ctcagcatca tctatttcta aaactcgatt gcgttcctcg tatacaagat ctcgctgtat
    18241 actaatgctt ttttcaaatt cattagccat ttcacgagct ttaacccctt gttcttccga
    18301 gatacgctgc gctttaacta caatttgctt aactttgcga ttaaacaaat tactttgcga
    18361 taatcgttgt gcatctaatg aatataattg attattttcc gctaaattac tatcgctcca
    18421 tcgcttaact aaataatcat ctagtgaaat atatatacaa gatgatcccg gatccccttg
    18481 tctaccagaa cgaccacgta attgcctgtc tacacggcta ttttccatat gttcatgaat
    18541 aataacagct aatccaccta atgcttcgac accttcacca agtttaatat ctgtgcctcg
    18601 acctgccata ctagtcgcaa cagtcatgga accaatttgc cctgcttcag ctatcatctg
    18661 cgcttctttt gcaacatttt gcgcaatgag taaattatta ggaatatcca tttggaataa
    18721 tactttcgaa aagtattcag ccgcttcagc agttctcgtt atgagtaaaa ccggtcgccc
    18781 cgtttcatga agttcaacta tatcatgaat catcgcgatg tttttctcat caactgaacg
    18841 aaacacttta tctggttcat cgatacgttg aatcgcttta tcagttggtg cttgtacgac
    18901 tatttttgaa tacaaatcaa agaactctga ttcgcctaat tttcctgtag ctgtcatacc
    18961 tgaaaatgat tcaaaaagtt taaataaatt ctggaaggta attgttgcca taacactttt
    19021 atctgttgaa acctccatac cttctttcgc ttcaatagct tggtgaagtc cagcttgcaa
    19081 cttagttccc ggtaacatac gacctgtaat acggtcaatt aaaacaatat caccattata
    19141 tacaaagtaa tcgacattag attcaaacaa atattgtgcg cgcagtgcta aattaatatt
    19201 acgcactagg accatcgctt gttcgctata taaatcttca acattaaagt atgattgtgc
    19261 cgcttcaata ccttgattta acagccatat ttcttttttg gtcttcttca ttttaaaatg
    19321 cacgtcttca atcaatgtat ctacaaactc tttcacaata tgaaatagat ttgattgtaa
    19381 tcttggtgca cccgaaataa ctaatggtgt ttgagcagca tctaaaatga ttgaatccac
    19441 ttcatcaata ataccgtaat ttaattgtgg taaaaatttc ccttccgcac tatcagccaa
    19501 attatcaatt aaataatcaa aaccgagacg tccattagtt gtatatataa tatcatgttc
    19561 atatatatta cgtttttccc ctttttgata ctcataatcc acaatatcaa caaaacctaa
    19621 tgaagcagtt aaacctaacc attcatataa tggttgcatc tcttcaaaat ctcgcttcgc
    19681 taaataatca ttcgttgtaa ttaaatatgt tccttttccc gaaagagcat ttaaatataa
    19741 aggcatcgtt gccgttaatg ttttaccttc gcctgtttgc atctccgcaa tgttaccttc
    19801 atgcaataca atcgctccga ttaactgaac ttctttagga tacataccta atactctcca
    19861 gctcgcttca cgtgccactg cataagcttc aggtaacaat gtatctagtg tatcaactcc
    19921 tgatgctaaa cgttctttaa attctattgt cttttgtttt aacgcatcat cagaatatga
    19981 tttaacttca tcgctccatg tattgatgcg tttcactatt tttctaatcg actttagtct
    20041 taattcgttt atcgtaacat ctagtttatg tttcatttac ttccccacca ttcagtttcg
    20101 atacatctaa gtaatctaaa aatcgtactg gattcattaa acgtgacata taatttagat
    20161 ggttgtcttg ctcttcttta aaataaaact cgacatttgt atcttttagt tcattatttc
    20221 ctgggacatg ttctgtaagc cattctttta aatcatcatc ttcatggctt gtacgatata
    20281 ctttgcaatc taaatgctga gcgacataag ttgcaaaaac atttgacttt gacccataac
    20341 taatcaaatt aatagccgtt agggtatctt gactttgcaa atcatccttt agttgcttaa
    20401 tattttcctt gatatcgtcg tccatccaac gttcaacgag ccaaacatga ccaaacagtt
    20461 tcaaaaaatc attcgaaata gttggatagg tgtcagatgg ttctgcaata atgacattga
    20521 tcctatcatt tccatattgg ttatcgtcta tcttcgtcac ccgcatgctt ttatactcta
    20581 aatcatcttg atgcgtcatc tctgtaattg ttaaacatct aaatattaga ctcgtcgatg
    20641 ctgcattcat catttttatt ttataagcat aggcttcatc aggatattga atcgtaatac
    20701 tatttgactt tacaatctca gtacttagtt ttgtgccatt tttattataa aaaatgatga
    20761 taaaatacac tgaaccagca ggcgttgcat caaaatcaaa atgcaattta taatgctgtc
    20821 ctctacgcaa aattggtaaa cttggcgcac ttttatattt tgaaaattgc tttaacatca
    20881 accactcatg aatcggtaat ccagagggca tcaaaggatt tataaaagtc acttcaccat
    20941 ttgaaaatga tactttagag ccatacataa atgtagtttg tgaaatataa ttccaagtaa
    21001 ctttaaatgt tttgtttttc agcatgttga actctcccaa acttgtcttc caaaataatg
    21061 ttgtaaaaat taacaaacca acttgcaatg gtaggtgaat catcattatg tcgcccagga
    21121 atactgcgat tcatcactct tgcttggtgt gctgtcaata caggtaatag ctcttgaaat
    21181 gcatgtggat cataatcatc atgttgcata tatgctatgg caaaaacagt ttgtgacaat
    21241 gatttctttt gaaatgtttg ccaaaatttt tgatttaatg cctttatcga cgcttgagat
    21301 gtatcacctt cattagacac caggacgtct aatgctgtac cgaactcttc tggtctaagt
    21361 aatcgcatat gttcagcaat cgttccaata ttaacaagtg gtttaccaac aataattgcc
    21421 tgaggattta actgagcacc ataatacaag gcaccaaatg aacccataga taaaccagat
    21481 aatattaatt catgtgattt aaaattcagc ttttctaatg tctcgtcaat aacattgata
    21541 ataccttgtt catattcaga tgaaccgata taaaagctac caccttcaac acgaggatcg
    21601 ccgataagta aaaacggtgc attcatacgt ttcatcatat aatatccttc gaaaccttcc
    21661 gctgttcgat aaccactaaa atatacgttt agtggcggtt tcatatcacc agggtggaaa
    21721 taataaataa attcctgtcg ttgactatct acgaaacgac taccaccaag taaaaattga
    21781 cccatgtcta atctagacca tcgtttgtgt ataggtccta aatgtaccgt cccgttccca
    21841 cgcgccttaa cagttacact tatataagca tcaaatggtt tcgcaggtat ctctaaagga
    21901 ctgtctaaca tatcatcagt taatatgatt tgttcaatta atgcaccatc agcgccagtc
    21961 tgaatcaatc taaatgtata ttgcaactcg accgcaccat caatatcaaa ttctggccat
    22021 atttgaatga ctttatcttt atcgtaaacg agattatttt gccaagatgc gataggttta
    22081 aattcttttc caaattctcc actcaacgtg agctctgaat taccttggta tacgacatct
    22141 actttaaaat tcggatgcac aagtgctaac ttaggggaaa ctttatctcc atactgtcct
    22201 gagaagctaa ctgcctctaa tttattatta cgttcttcaa tattccggta atgtaatggt
    22261 tgaacaacgt atttttggac attttcgtct tgttcatatt caactgacca aaatgattca
    22321 tcaacatacg tattgtatgg ttcgcttatc atttgtaata aattcgttaa tgtctccgag
    22381 tatggtgctt gaatatagat aaaatcaaag cgcccttctg cttcaacaat cgcttcaata
    22441 gcctctacat aaccactatc aaattcaaac aatccaatat cgaagtaatc ccaactcaca
    22501 ccttttttgt gttgaaaaat aggttctaaa tcgtctcctc caatttgcaa aactctaaat
    22561 ttacgtggca tcattttcac cttctattaa ctcatcgagc tgattaataa tattcttaga
    22621 agcatatgca tctattaatt ttaaagaata ggcgtacgca taattccaat ttttcaaata
    22681 aaataaataa taatttaacg catcatctaa ttcatcaact gtatttataa tacggccatt
    22741 gtcataatca gagacgtaat ctgtttgttg accattaatt tgtggaatcc cagcgctaat
    22801 tgcactaatt tgtaaataca aatcaggttc ttttgacata tctatcacaa gtcgcaacgt
    22861 ccgcaatgct tctacaacat catgttcagc atgtatcgtc ttaacagcaa tgatgtcatc
    22921 ttgatcttca ggtgtcatta atgctgaaac attaacatcc gcattctgtt tagcttggta
    22981 ttcctcattt accgacgtaa tacattcacg aagccacatc ggtatgtcat tttgatggcg
    23041 cgataataaa attaaacggt aataatcttc ctgtgcgata taatccacaa gtcgttgcat
    23101 catttgttgc aaatcagcgt cactcatacc atctatccat acacctataa atgtttccat
    23161 caattgacta cttatattag gtgattgtct cgtttcaaat ggtgtgattc gaatcattgt
    23221 attctcccgc tgatacttct cttgatgact aattaaatca cgttctagtt gcacactatc
    23281 aacaattaaa tgggcattct ttacgataga ttgatattcc tcatctgaca cagtttcatt
    23341 tctattttta aaaaatgaat aacttaacaa tttcgctgga atatgattgg ctatttgtcg
    23401 attgtgccta gcatctgaag ccacaatcac atgatcatct tcatgtattt gttgtgcaat
    23461 cattgcttga aatttttctt caattagttg agccatattg ttatattctg tttgttgata
    23521 gtgatgttga tatctttttg atacagtgac tctgccattt ttcaaatctt catgaagtac
    23581 acaatctcca ttaatcgtta aatattgttg gtaagaagcc tctccctgat catcaaaata
    23641 acgtatcgct gataaataac ctctgtcatc aaaaatataa cgccgttgta actgatctct
    23701 ttcaaattct tcaaaccaaa ttgaataccc ttcttgacta aaataaatat ttgtataggt
    23761 ctgttcactc gtcacacatt ttaataaata cggcgtgtac acaaactcaa catcatccgg
    23821 ccattttaag tgatgataat taatcgcttg tggcgcatgg tgactgaatc cttgaatttc
    23881 atcaaacaca gacgaatact ttgtttcata taagtcatat cgatgtaaaa atgttcttaa
    23941 atttggtgca tgattgagaa caatcagttg ataatctaag tcattttcaa ggtgcattcc
    24001 cattaaacta atcatatcgt caaattccgt cttattttgt agttgataat acggcacagt
    24061 cgtgtcttgc caccatcgtt ggtcatcgta ccaagctgga ataaagtatt tcataattac
    24121 ctccttacca atactggttt aaaaatggct tatatttatc aaaatataaa tatgtacgaa
    24181 ttgtttctgc aatattaata ctgatgtaaa ctaatacaat cagttgtact gagaaataaa
    24241 tttcagtaga taaatgcggt acaaacaatg tgaaataaag cggtatacca ataatgactg
    24301 taactaatgc cgatccaaac caacatacgc gtcttgcttg ataatttaaa taacgttctg
    24361 tatccttacc aggtttaact cctgaaaaat aattgccact ctttaagaaa tctttggatt
    24421 tttgtttagt attgattaaa aatctcgata aaaaataacc caataacatt tgaatcacta
    24481 aatatactga aatacctact ggactatcaa atgtcagcat tggcatgtca tctgatatgc
    24541 ttttattaaa catagataaa ataaaatgaa tgccactttt caagaaaaca aatgctgaaa
    24601 tactcatcat taaagtaata ctgcctgcag ggttaacttt ccaagataaa taagatttca
    24661 tatttgttgc ggaaacgttc attaaatcga tatatggtat tctcacttct actaattcaa
    24721 tgaataataa gataaacaat gtgattatca caaggatgat taacaacgca atcacaatat
    24781 gacttgcatc tatatattcc attttttgat gcatcattga tttaataatg ctaaccatta
    24841 caatcggcat tggtcctgcg atgccgtaac gactattttt gtcagctaac caaactaata
    24901 atatcgttcc agtaaccaaa atcaatattg ttaagtaaat attgtcttga tgaacacgtt
    24961 ctttcgaaac atattcatga atcacaaaat aactttgaat cacacttaaa attaatgtta
    25021 agatacgctc tttataatgc ttctcaagac ttgtttgttt catgtattta tccatattcc
    25081 gataagaaat cagcatcaag ataatcattg atgttaacca cggaactaat cctaaagtga
    25141 aaatgtttaa agtattaacg tctccaccca tattagaaat agctatttta aaaaatgact
    25201 catgttttac ttgcatatcg ttataggaaa cgatggaaat gtttgtacct aatatataaa
    25261 taaataatat aaaacatgtg tatagcatac gtttatatat aattttatat tcgtattgtt
    25321 gtaaaagttt taacatgttg cacctctttt atatcaaaaa cattaaaaag actaagggtt
    25381 catcactaat tattaaaatc ctatatcgat ttttctagtg attggtgcct cagtcttttt
    25441 aattttagcc agctataaat tcaatttatg cttgagaatc atcttgatca ttttcatctt
    25501 tctttttctt tctcttcatt aaacctaaac caactaataa tgtcataacg ccacctagta
    25561 atccattttg ttttattgag tcacctgtat ctggcaatct tttttcactt tgtgcaggcg
    25621 tgccattatg tttagtcact tcagatgttg cacttaatgt agactgagat tcactcgtgc
    25681 tcgttgttgc ttcacttgat aagcgagatg tgctcgtgct gtgagtatga tgcatactca
    25741 ttgagtctga cggatgcatt gagttagatt cagatgtact tgttgagccg gacatacttg
    25801 ttgatgttga gtcagaaatg ctttgtgaac cagacataga tgtactcagc gattcggatg
    25861 tgcttgtcga atcggatgtg ctcaatgacg ttgatgtgct tgttgacact gattctgagt
    25921 cgctaattga tgttgagtcg gatttgtctt gtgacattga aacacttgtt gaatcggatt
    25981 cactcattga tgttgagtca gatacgctcg ttgaacctga accagacgta cttaatgatt
    26041 cagatatgct tgttgaagtt gaaccacttg ttgagtccga tgtacttgtc gatgtcgagt
    26101 ctgaatctga tgtactcaat gattctgagt cactgataga agttgaatca cttgtagatt
    26161 ctgattctac tgtactttgt gaaccactga tacttattga agtagaatca ctgatactgt
    26221 ctgatgttga taatgatgtc gacaccgatg tgctttgtga tgacgatgta ctagcactca
    26281 ttgacattga tgttgatatc gatgtactta aggaaccaga tgcacttgta cttgttgact
    26341 ggctttgtga cattgaatca cttaatgatg tagatgtgct tgttgagctc gagtcactta
    26401 cacttgttga acctgatatt gagtcactta aacttgtcga tgttgaaact gatacgcttc
    26461 cgctcattga gtcagatgtt gaaagtgatg tactcgttga atttgatcca ctgatgttag
    26521 acgaatcact tgtagacatt gagtcgcttt ctgatgcact gatgctcata gagtcaaatt
    26581 gactattact tgttgagctt gactgcgaat cgctcacact tgttgacgtt gattctgatc
    26641 cactcatact ttgcgagcta ctcaatgatt ttgaatcact taatgaatcc gaagtgctaa
    26701 gacttgtgga accacttaaa gatattgatc cacttaatga gtcggagtca cttgtactag
    26761 tagaatcact cattgatatt gaatcactta gcgaggtaga ctcgcttacg ctttctgaac
    26821 cacttaatga tgttgaggta ctcaatgaac cagatgtact tgttgaagtc gaaccacttg
    26881 ttgattttga atcacttaat gaatcagatt cactcacgct ttctgaactt cttagtgacg
    26941 tcgatacact taatgatgac gaatcgcttg tgcttactga atcgctcatc gattgtgagc
    27001 cactcaatga acttgactcg cttacacttt ctgattttct taatgacgtt gagacgctca
    27061 atgagccaga atcactgaca cttgttgagc cactcatcga tttagagtca ctttcagaat
    27121 tagattcact tacactttct gaatcattta cagattctga catactttgt gaatcagata
    27181 tgcttgcgct cattacttca ctagccgatg ttgatgtact tgtcgaatca cttaacgata
    27241 tagatacact catcgaacca gatgtactcg cacttgttga gtctgatgtt gaatcactca
    27301 cactatcaga taatgacgtt gaatcactca tacttgttga tgtacttgtt gaaagcgaca
    27361 tactttgtga atcactagta cttgtacgca tcgaagtact agttgaagct gatgtactac
    27421 gagagtcact tgttgatgtt gatgtacttg ctgatcctga tgcacttgta cttcttgatg
    27481 tgctttgtga atcgcttaat gatgttgatg ttgaatcgga ttcacttgta ctttctgatg
    27541 ttgagccaga ttctgatgta cttaccgatg ttgataaact tgcaatggtc gacatgcggt
    27601 ttgaagttga tgtacttagc gaatcactta atgatgctga tgtgctttgt gaatcggatt
    27661 cactgctttg cattgacgca gatgttgaat cacttaaaga tgttgacgac gaatcggatt
    27721 cacttgcgct tgctgagtta ctgagcgatg ttgacgtact tgctgatcct gagttacttg
    27781 tacttgttga gtcactgagt gatgttgacg cactttctga tgttgattca cttgcacttg
    27841 ttgagatact ttgtgaatca gattcactct ctgaaccact taatgatgct gatgtgcttg
    27901 ttgaacctga ttggctcgta cttttagata tacttgttga atcgcttagt gacgttgatg
    27961 tcgatgttga ttcactttgg cttgttgact gacttgtata tgttgatgtg ctttgtgaat
    28021 cggattcgct cgtgcttgta cttgttgagt ttgaggcact ttggcttgct gagtttgagt
    28081 ctactccgct ttgattcatt gatgcactta gtgacaatga cgtactcgtt gagtcagaca
    28141 aacttgtact cgttgacgta cttgtacttc ctgatgttga ttgagacata cttatgctca
    28201 ttgatgttga atcggattta ctttcacttg atgatgttga gtcggattca ctttcacttg
    28261 tagaaccact taatgatgta gatgtactaa tggaatcaga tttacttgta ctgattgaat
    28321 cacttgtcga cattgatgta cttaatgaat cagacttact atcacttgtg gaatcactta
    28381 atgatgttga caaacttgta gagttagaca aacttgtact cgttgacata ctcagtgatg
    28441 ttgaaacact ctcgctctta aacgttgacg ttgattcact gatacttgtc gatgttgaaa
    28501 tggacgcact accacttgtt gaattactta atgatgttga tgtgctacca gattctgatg
    28561 tactgtctga taatgacgta ctctcacttg tcgaactact cactgactct gatgttgatt
    28621 cagacgtact ttcacttaat gattcactta aaaaggcaga tgcactttgt gattctgaat
    28681 cgctagtact atttgattca cttaatgata tagacgtgct ctctgaagca gatattgctt
    28741 cacttataga atcgctcgtt gacgttgatt cacttattga atcagactct gatgtactta
    28801 agcttgtgga atcactcaca gatgttgatg tacgttctga attacttgta cttaacgatg
    28861 tcgaagtact taccgaacca gatgtgctcg tagaagcact ttgtgatatt gattcacttg
    28921 atgcagttga tgctgatttg ctatcactcg ttgaatcact aaacgacgtt gatatgctca
    28981 ttgaatcgga ttgacttgca ctcattgaac cagacgtact ttgcgattcc gaagtacgta
    29041 ctgaagcact tgtcgacgtt gatgtacttg ttgaacctga ttgactagta cttagtgata
    29101 atgacttact atcagaatca gatgtacttt gtgaatcact taatgattct gatgtactac
    29161 ctgactgaga cgtgctcatt gaactactta cagacattga tttactgtct gatgcagata
    29221 atgacccact tgtactgata gagtcactta ctatctctga agtactcatc gagtctgatg
    29281 tacttgttga gacactttgt gatgctgcta tgcttagtga tccagaaaca gaaccacttg
    29341 tgctcgtcga atcgctcaat gattctgatg tactcatcga ttttgaatca cttgtactta
    29401 atgatattga tgtactttgt gaatctgatt tgcttgttga cgcactttga gagttggcta
    29461 tgctatttga aatactgata gagtccgagg tgctagctga ctcgctcaat gatgttgatg
    29521 tactaattgc attcgatgta ctgtcactta atgatgctga tgtactagac gaccctgata
    29581 tactcgttga taagctttgt gacttagaca agcttcctga tgtactcata cttaatgagt
    29641 cactgagtga tgttgatgta cgcaatgaat cagatgtact tgttgataga ctttcggatt
    29701 tttcagtact gttagagttc gaaatcgaat cgcttaatga tgttgattta ctaactgaac
    29761 ctgacatgct tgatgataca ctttgtgaat tcactaaact tgtgcttgtt gagcttgata
    29821 cactattact ttcagatgtg cttaatgact tagatgcact cacagaatca gataggctta
    29881 cacttgtcga tttcgaggta ctagctgatg tagataccac aatcgatcct gatgtactcg
    29941 ttgatgcact ttgtgagtca gctttacttg ttgagacact ttgagattgt tgtgtacttc
    30001 ctgatgttga tacggaatca ctcatgctat ttcttgttac ttcatattta aaagttgtcg
    30061 tcgttttgtt accgctcgca tctgtagaaa cgattgatat agtacttgta ccaatgtttg
    30121 ttggtgtacc actaatagta ttatttgtac tatcaaatgt tagtccggat ggcaatccag
    30181 tcactgtatt cgtcaccgca tttccactgt tatcttgcgt agcaatttta atcggggata
    30241 ttggtgaata cacttctgat gattgatctc ctattggtgt cactgttggt gctgtcgtat
    30301 ccacaacatt tattgtaaaa gttgtcgtcg atttgttatt tgcttggtca gtagacacaa
    30361 ctgtcactgt tgattgacca atttttgttg gtgtcccaat gattgaattc gttgcactat
    30421 cgtaacttaa tccgcttggt aatcctgtaa ctgtatttgt cacagtccca gtaccattat
    30481 ccgttgtagt caacacaaca ggattcattg ttttacccac ttctatggtt tgattgccta
    30541 cagttacagt tggtgctttt acatcagtaa aataatatgt cactgattgt ccagcattcg
    30601 tcatttttac agttttattt gtatcattat aagttgacgc atatgaacta tcgacggacg
    30661 tgtagttata tcctttagca gtcaatgcag attgctgatt atcgattgtc acgacttgat
    30721 caacatttcc tgaatatgtt tttggtggaa taatatcttt acctgttgtt acatcaacgt
    30781 atctcacttg tgtaacagca gactctgtat attcgaatgt tccaaattgt acttgttgta
    30841 aatttgtcgc gccacctgtt gaggctgtca ttgataatga aaagttggtc gtaccacttt
    30901 tcgcaatcca atctgaaata ttacgtgtcc atgtttgacc tgcatatttg acagtcataa
    30961 cctttgtatc accattatag ttaatatcaa aatcttggaa cgtgttattt gtaggttgaa
    31021 catttaactt cgcagcatta tcagctgttg aacttgatgt atacgttgtt gcaacaccat
    31081 aactatctgt tgttacaaat gcaccaaacg cacctccacc agctacatta gatgggtcag
    31141 cattcgcctt tgcagctgaa tttggtttag atgtattgtg atacgtatcc aatttgaagc
    31201 caaatgcgtt acttaagcca ccaataccta ctgcggcacc gtttaaccct gtttcaccta
    31261 atacacctgg tgaaaaggca aaaccgatac catctccacc atttccatgc ccttcatatt
    31321 tgttacctaa atttactttt ccagaaaaat gaaaactctt attagagtca atacgtgttc
    31381 ctaatgtaat agcacctttt tggctgtatg catcctgtgt taacgtcaca ataccggtac
    31441 tttgatcata ggtagcatta cctgacgttg tcatatattg ttttaagtta tctttattaa
    31501 ctgtaattgt attagcagtt actgcggttg tcgtcgctgc tgacgcaaat gttgacatag
    31561 ctaagcgact gaaagttcga agttttactg gtgcggtgct agttgacgtt gtgctagttt
    31621 tgtttaagtt gaccgaagat ggcgttgtgc tttgtgaagt gttatttgat gcagtacttt
    31681 gatttgttga tgtattaatt ggttgttctg tacttgaagt tgaagctaca gatttagtat
    31741 cagaacttga tgtagtattc tttgaggatg ttgattctga tgtagatgtc aatttctctt
    31801 gttgattgct tgtactatta gttgtcgaag tgaccttttc agacttttca cttgagactg
    31861 tgtcactatt tgatgtttgt accgaactac tatttttcgt tacacttgtg gaatcggctg
    31921 ttgatgttga tgcttcgatt gtcgttgagt tttgattacc tactgtttca ctttgtgtgt
    31981 ttaattcaga agttaatggt gcatcagaag ccgcaaaagc ttgctggtca tgcaacatat
    32041 ttaccgtgaa tgcaccacca ataaccgccg tagttttcag tccgtatccc gtcatttttt
    32101 tactaatgct ttgattatct tgactcacta aactatgact aataaatggt agccccataa
    32161 ttttgaacat ttctatttct ttaattccgg attttaccca attttttcca gatttataaa
    32221 gtcttactct tgttttttcg tttgctaagc tgtcatgaaa tgctttctgt cttttactca
    32281 tgtaataact ccttgtatta tctttacatt cattagatta taatatatgc cactattcaa
    32341 tttaatacaa ctcttttttg atacaaaaat actcattttg ttaaaatttg taaaaattca
    32401 tttttattcg tctagatgga atcgttttca tatttttaaa attacttttt ctcgtttatg
    32461 cgtataatct tttttatata aatttggcta attggcttta tgtttaatca ttataattgt
    32521 ttcgttttta aaataattat tgtattaata tatctatatc atccaccttt tatttataaa
    32581 tagttaattt acaac
//
LOCUS       DAPDIM010000031        31890 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000031 DAPDIM010000000
VERSION     DAPDIM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 31890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31890
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.031"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(109..1482)
                     /locus_tag="RFE25_001460"
     CDS             complement(109..1482)
                     /locus_tag="RFE25_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EVE domain-containing protein"
                     /protein_id="HDU2816529.1"
                     /translation="MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRA
                     FKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKR
                     SEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIY
                     THTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNST
                     VIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGL
                     KSPFEMVKKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPD
                     FSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLE
                     GYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTR
                     IVKVKHD"
     gene            complement(2154..2384)
                     /locus_tag="RFE25_001461"
     CDS             complement(2154..2384)
                     /locus_tag="RFE25_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816530.1"
                     /translation="MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAM
                     LTFKDKQISASLKFSALLINVLPLCGTFVASN"
     gene            complement(2415..3353)
                     /locus_tag="RFE25_001462"
     CDS             complement(2415..3353)
                     /locus_tag="RFE25_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001620169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I mannose-6-phosphate isomerase"
                     /protein_id="HDU2816531.1"
                     /translation="MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGT
                     SEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYE
                     HENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEF
                     YFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNA
                     PLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMI
                     VDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV"
     gene            complement(3789..4454)
                     /locus_tag="RFE25_001463"
     CDS             complement(3789..4454)
                     /locus_tag="RFE25_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDU2816532.1"
                     /translation="MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQG
                     MKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKE
                     ANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAA
                     GSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEI
                     EKD"
     gene            4606..4926
                     /gene="czrA"
                     /locus_tag="RFE25_001464"
     CDS             4606..4926
                     /gene="czrA"
                     /locus_tag="RFE25_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)-responsive metalloregulatory
                     transcriptional repressor CzrA"
                     /protein_id="HDU2816533.1"
                     /translation="MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGH
                     ISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPK
                     ESGL"
     gene            4928..5905
                     /gene="czrB"
                     /locus_tag="RFE25_001465"
     CDS             4928..5905
                     /gene="czrB"
                     /locus_tag="RFE25_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc efflux transporter CzrB"
                     /protein_id="HDU2816534.1"
                     /translation="MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLAN
                     SLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVI
                     SILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFL
                     HVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGT
                     PSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLEN
                     IEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH"
     gene            6171..7262
                     /locus_tag="RFE25_001466"
     CDS             6171..7262
                     /locus_tag="RFE25_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDU2816535.1"
                     /translation="MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKY
                     AQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVK
                     FTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYAD
                     STHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFK
                     AMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTI
                     ILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVE
                     TKTEKAQDSLNDNTTKTMTSDKPEDNQPK"
     gene            complement(7695..7799)
                     /locus_tag="RFE25_001467"
     CDS             complement(7695..7799)
                     /locus_tag="RFE25_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816536.1"
                     /translation="MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK"
     gene            8479..8637
                     /locus_tag="RFE25_001468"
     CDS             8479..8637
                     /locus_tag="RFE25_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001792784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDU2816537.1"
                     /translation="MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTS
                     GRINRRFK"
     gene            complement(9295..10152)
                     /locus_tag="RFE25_001469"
     CDS             complement(9295..10152)
                     /locus_tag="RFE25_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDU2816538.1"
                     /translation="MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLAT
                     GRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFNHGLSLAQVQQITNLAKRQQIY
                     YEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEG
                     EYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMI
                     AHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAK
                     YLAKHFLAD"
     gene            complement(10220..11002)
                     /locus_tag="RFE25_001470"
     CDS             complement(10220..11002)
                     /locus_tag="RFE25_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816539.1"
                     /translation="MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTL
                     LNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVI
                     SGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQ
                     PQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLK
                     DGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE"
     gene            complement(11234..13039)
                     /gene="glmS"
                     /locus_tag="RFE25_001471"
     CDS             complement(11234..13039)
                     /gene="glmS"
                     /locus_tag="RFE25_001471"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDU2816540.1"
                     /translation="MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTV
                     FKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGV
                     IENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALG
                     LLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKD
                     EVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEG
                     NLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMP
                     LLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAG
                     PEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEVIVDDAPIM
                     EQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIE
                     DGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTP
                     LVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE"
     gene            13720..15258
                     /locus_tag="RFE25_001472"
     CDS             13720..15258
                     /locus_tag="RFE25_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDU2816541.1"
                     /translation="MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFID
                     NGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPM
                     LLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLM
                     KFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQS
                     ILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLF
                     IAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFV
                     VAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETS
                     SSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGIND
                     ITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKK
                     DDQA"
     gene            15293..17425
                     /locus_tag="RFE25_001473"
     CDS             15293..17425
                     /locus_tag="RFE25_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDU2816542.1"
                     /translation="MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKG
                     VEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALI
                     QAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR
                     EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPY
                     QLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYD
                     VTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTL
                     VDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEI
                     AFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLK
                     SLDLSQNDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMI
                     DKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKLEQLLHHMRSGLTLLDSVKI
                     VSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNM
                     IKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLES
                     IDTFMENPQELETLLRNKFLERIKKQFI"
     gene            17437..17871
                     /locus_tag="RFE25_001474"
     CDS             17437..17871
                     /locus_tag="RFE25_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDU2816543.1"
                     /translation="MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAM
                     KDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGK
                     DGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA"
     gene            17871..18977
                     /locus_tag="RFE25_001475"
     CDS             17871..18977
                     /locus_tag="RFE25_001475"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDU2816544.1"
                     /translation="MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDH
                     QYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFA
                     PFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
                     ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGRFA
                     GKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSD
                     EVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKN
                     NYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS"
     gene            complement(19296..26741)
                     /locus_tag="RFE25_001476"
     CDS             complement(19296..26741)
                     /locus_tag="RFE25_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HDU2816545.1"
                     /translation="MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQP
                     AQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQGNQADPNNAA
                     QAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPN
                     ASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRS
                     DMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGITKTVNVKPDSELIINFTTMQT
                     NSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADAS
                     RITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGAS
                     LKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQTANKVTFTSQGV
                     TTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEV
                     TLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVE
                     TANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVT
                     KINNDKNNAIAEINKQTTSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRK
                     QQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPA
                     TTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQ
                     DLERVKNEEIFKIENITDSTQTKMDAYKEVRQAATARKAQNATVSNATDEEVAEANAA
                     VDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQAKVKPAADTEVENAYNTRKQ
                     EIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAAT
                     TKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTD
                     VDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDANNGSTTEEKEAAKQQV
                     QTEKTAADAAIDAAHSNVEVEAAKNAEIAKIEAIQPATTTKDNAKQAIATKANERKTA
                     IAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVN
                     KKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQV
                     DEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATNEEKEAAIQQLA
                     TAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAI
                     DNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTI
                     KDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVN
                     TAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRA
                     AYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIE
                     QTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYK
                     KDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEV
                     QIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQN
                     VQTALENINNGVDNGDVDDALTQGKAAIDTIQVDATVKPKANQAIEAKAEDTKESIDH
                     SDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQ
                     KAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATV
                     KNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFD
                     RFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPDANDTNNGTDNNDATANSNANAT
                     PENTGQPNVSETTDNGKADASPTTPNNSDAATGETTVTSATDDAKDKPQANNNSSADA
                     STNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTG
                     STATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKA
                     EKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVA
                     SNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQKSVGPVA
                     NNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNGSHSMHQDMLNVTKPEENK
                     ANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTE
                     E"
     gene            complement(27019..28374)
                     /locus_tag="RFE25_001477"
     CDS             complement(27019..28374)
                     /locus_tag="RFE25_001477"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDU2816546.1"
                     /translation="MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPR
                     VLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISAS
                     HNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQK
                     YLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKC
                     GSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQE
                     LNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVM
                     MDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDV
                     KEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLD
                     K"
     gene            complement(28401..29333)
                     /locus_tag="RFE25_001478"
     CDS             complement(28401..29333)
                     /locus_tag="RFE25_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HDU2816547.1"
                     /translation="MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTI
                     QDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQ
                     EKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQ
                     TVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNL
                     QVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDL
                     DGISESTEKTVKINLPEHVTKAQPSETKAYINVK"
     gene            complement(29335..30144)
                     /locus_tag="RFE25_001479"
     CDS             complement(29335..30144)
                     /locus_tag="RFE25_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDU2816548.1"
                     /translation="MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQL
                     LKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFL
                     KRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNIS
                     QELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEV
                     SDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK"
     gene            complement(30333..31241)
                     /gene="rocF"
                     /locus_tag="RFE25_001480"
     CDS             complement(30333..31241)
                     /gene="rocF"
                     /locus_tag="RFE25_001480"
                     /EC_number="3.5.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginase"
                     /protein_id="HDU2816549.1"
                     /translation="MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDL
                     DVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGD
                     HSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLE
                     LNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKS
                     RNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVN
                     PLIDSNNHTAEQAVSLVGTFFGETLL"
     gene            complement(31379..31451)
                     /locus_tag="RFE25_001481"
     tRNA            complement(31379..31451)
                     /locus_tag="RFE25_001481"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31416..31418),aa:Lys,seq:ttt)
     gene            complement(31455..31529)
                     /locus_tag="RFE25_001482"
     tRNA            complement(31455..31529)
                     /locus_tag="RFE25_001482"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31495..31497),aa:Gln,seq:ttg)
     gene            complement(31539..31622)
                     /locus_tag="RFE25_001483"
     tRNA            complement(31539..31622)
                     /locus_tag="RFE25_001483"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31586..31588),aa:Tyr,seq:gta)
     gene            complement(31652..31727)
                     /locus_tag="RFE25_001484"
     tRNA            complement(31652..31727)
                     /locus_tag="RFE25_001484"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31692..31694),aa:Val,seq:tac)
     gene            complement(31735..31806)
                     /locus_tag="RFE25_001485"
     tRNA            complement(31735..31806)
                     /locus_tag="RFE25_001485"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31771..31773),aa:Glu,seq:ttc)
     gene            complement(31808..31882)
                     /locus_tag="RFE25_001486"
     tRNA            complement(31808..31882)
                     /locus_tag="RFE25_001486"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31848..31850),aa:Asn,seq:gtt)
BASE COUNT         9605 a         5723 c         4911 g        11651 t
ORIGIN      
        1 gctcttatgg ttgattaccc gtcatttttc tttatgcggt tattcaaata tgcaattatg
       61 caatttttaa tcctatcctt acttcttttc aaaaactacc atatatcatt agtcatgttt
      121 gactttgact atacgtgtgt attttaaaaa ctgctctgaa tatttctcct taatttcctc
      181 taaactgtca tatgtaatac ctacaatatg ccaattagga ttgaaataat agaaagaatc
      241 tttttgtcgt gaccatttaa tcatattacc gtctttatta taacgtggta atgttacttc
      301 atagccttct aacacattaa tatacgtttg gaaaatgtct gtatctatac gattaaaatt
      361 atcaataact aaataacttt tatccttttt aggcattaat tgagtaataa acccttcacg
      421 atagtataat gcccctgttt catttggtaa atacttgcca taaagcatat cttctgaaaa
      481 atcaggatga cctgttgtta taacaggatt tgcattcgct ttttgcaata agtcattagc
      541 cgcttttaag ccctcttctt ttcgatctac aacaagtaaa ataaatggct ttaacgcttc
      601 ttctttttca ctttcaagca tatctggttt tttaaccatt tcaaatggag atttcaatcc
      661 attattatcg ctcatttcaa taattgcatc atactgtgct tgtgacatac ttgcaatagc
      721 ctgttttgca ttttcttgaa ggaaatataa atttttcaat ttaggatgct tatttaatgt
      781 acttaatgta atcggcgtaa tgtctttctc ataagacact tcaatcactg tactatttgt
      841 tctaccagga attggtggtt tttcatgaat atgctttgaa acttctccaa ttccaacgac
      901 agattgattt ttcgttcgat tataaaaaat aatattgtcg ccttcttcta actgagtata
      961 aaaatgataa ccattacgtt taataccgtt gtacgtgtgc gtataaatcg tatattggtt
     1021 tccaggttca aattcttcag tttcagctaa aaagaaataa cgtggtatct taatttcgcc
     1081 tttaccaaga ccacttatta aatcaaactc ttctgcagtg atttggttga acaatgtctc
     1141 tttcatatta ctcatacgaa attccaaagc ttcactacgc tttaaataat cagctgttaa
     1201 tggtttcaat tgttcattaa aacgaaactg tacacgtatt ttattttgtg cacctgtttc
     1261 aacactaata atttcaccac atccaagtag tccagtatcc gtctgaactt gataaaagat
     1321 gacttgatct cctactttag cctttttaaa cgctctaaat ccttgagatg ggttaaaatg
     1381 tgcgcctgat tcaaataaag ctgtttgtcc tactaacggt tcattatgat tccaacggtt
     1441 atatccacaa ttcaaccaaa aataattcgt ttctgctgtc atcttaatac tccttaacct
     1501 gaataaattt tagaaacact atgaattaca ttcttttagt gtttcttatg cagttggacg
     1561 cgtatgcgaa caactgtata ccctttgttc actgcgattt taatcgcatt tcctataaca
     1621 ttgtagcgcc caggacatta atttacgtcc cagaccctta tcgttttcac ttctaagtaa
     1681 gtcgaactat tttgctttac aacaagtgcg actctaaata cagttggaca cacatacgag
     1741 caactgtata ccttttaatc agttttctat attttattta ttatatctgt cttaatgata
     1801 aaaattgtta caaacagttt aacatattta gctacctatt ttgcatataa aaaacatgct
     1861 tgcatacact atgcaataaa aattacaaat ttatatatga taccactatg cttgcttatc
     1921 tctatagcgc cattgataca catttttaaa tatctatact gccgttagaa ttttatcatg
     1981 tcttaatttt cattaaatat taattacttc attttatata aaccaacaaa aaccccctca
     2041 ctactatgca agtgagaggt tatgttgatg tgctttattt tcatcaatgt cattaacacg
     2101 atcatatttc ttctgttaat gcactgtact ttattcaaac gcgctatcga caattaattt
     2161 gaagctacaa aggtaccgca taatggcagc acattaatta acaatgcgct aaactttaat
     2221 gaggcgctga tttgcttgtc tttaaaagtc aacatagcac tgataattcc taaaatagct
     2281 actatacgtg gaattgtcat gctcggatac tgcggtatat gtaagaaagc accaagacct
     2341 gctatcacac cacatactaa cgcaatatat agaaattgct tcaaatcatt cactcctaaa
     2401 ttgttattac actattacac atagctaatc atcaatgtga aatcgccttc aaagacacta
     2461 tccaaatctt cagaagtcaa aataaagttt gtaccagtag tcagtttgaa aatttcacca
     2521 tcgacaatca tttgtccttc accttccaac actgtaacta aacagaactc tctaggcttc
     2581 atataattta acgtgccaga aatttcccat ttaaccaatg taaagaaatc attcgataca
     2641 atgtgtgtac acttatggtt ttcaataatt tcactttcag gcaaaatatt aggtaatggt
     2701 gcattgtact gaataacgtc taaagctttt tcaatattta acggtctatc attatattga
     2761 ttatcttgac gattgaaatc ataaagtcta tatgtaatgt ctgacgattg catcgtttcg
     2821 tatgctaata ttcctgaaga aatagtatgt actgttcctg ctggaataaa atagaattct
     2881 ccaggtttta ctttaatata tctaagtatc gactctatcg ttccgtgttg aacatgattc
     2941 gcaacttctt ctctagactc tgctaatgtc cctataacta tttctgcatc ttcttctgca
     3001 tctataatat accaacattc agatttgcca tattgcccgt tttcatgctc ataagcataa
     3061 gaattatcag ggtgcacatg aatagaaagt gattctcttg catccactat tttagttaga
     3121 agcggaaaat ctttgcttgg gaaatcacca aacaattcac gatgttctga ccaaatacgg
     3181 tctaatgttt gaccttgata tggtccatta ataatctcgc tcgtaccatt tggatgtgct
     3241 gacacacacc aacattcccc agttgtatca ttgtctaatt gatatccaaa ctcacttaga
     3301 cgttgaccgc cccataattt tgtttttaaa attggttgta aaaataatgg cattgttgca
     3361 cctccattgt gattaagtaa gcaatagaac tctgatgttg ttgttccatt atattttgat
     3421 tttgttctca tttacatcgt attataaact tccacatttc aaattaacta ttagtgattg
     3481 taccatattt actaacattg cagtactgcc aattaaagcg cttcacttaa atttacagta
     3541 ctttaacatt tttaaaaatt aatagcatag agattatctc tctcttacat ttgtacacat
     3601 ttccctttaa atttactcgc ccattatacc aattaataaa caactttaat agttgtgcca
     3661 tacattgttc aaattctttg taaaatgcat agacaatacg tacttattca tacttataat
     3721 tcatcatttt caaaaaaata acgagttacg aaaacgtaac ccgcttcaaa tcatatttac
     3781 tatccttatt aatccttttc aatttcaaat tgagttaaag catctttaat gtcctgctca
     3841 ccactaataa tttgaaactc ttggtgatta aaatgattgg atgtgacaat ttcttttaat
     3901 actgtcgcaa catcttctct aggaatttca cctttaccat caaaatattg tgcagcttct
     3961 atctttccag atcctgctgc atttgtaagt gcccctggat gtaaaattgt ataattcaaa
     4021 cctgaacgtc ttaaatagtc atcagcgtaa tgtttagcta ttgtatatgg ctttaaatca
     4081 ccgctatcat caaaagcctg acgtctcgaa tcatatgttg aaaccatgac atagtgttta
     4141 atattagcct ctttactcgc aatcattgat ttaacagcac catctaaatc gacaataatt
     4201 gttttatctg cacccgtgtt ccctccagaa cctactgaaa agataacttt atcgaatggt
     4261 ttaaacgtct cagttaaagt ctctattgaa tcattttcaa catcaacaag aattgctttc
     4321 ataccttgtg attttaacgc attaagttga tctgattgcc taacaccagc agtaaatggt
     4381 acattttctt ttgctaattg ttgcactagt aacgaaccta caccgccatt agcacctata
     4441 accaaaatat tcatttacaa cactctccta tttattattc tctatgccat accactttat
     4501 gagatatgta aaacttgtta caactataaa aatcaattga catactactg ggaacgtatt
     4561 aaattaatat atgaacaaat attcatatga aaggattgtc atataatgtc agaacaatat
     4621 tcagaaataa atacagatac attagaacgc gtaactgaaa ttttcaaggc attaggcgat
     4681 tacaatcgaa tacgtatcat ggaattgtta tcagtcagtg aagcaagtgt tggtcacatt
     4741 tcacatcaat tgaatttatc tcaatcaaat gtctcgcacc aattaaaatt acttaaaagt
     4801 gtgcatcttg tgaaagcaaa acgacaaggc caatcaatga tttattcatt agatgacatc
     4861 cacgtagcaa ctatgttaaa gcaagccata catcacgcga atcatcctaa agaaagtggg
     4921 ttataatatg tctcattcac atcatcatga ccatatgcat agtcatgtaa ctacaaataa
     4981 taagaaagta ttgtttatat cgtttttaat aatcggtcta tatatgttta tcgaaatcat
     5041 cggcggtctc cttgctaaca gcttggcatt actatctgac ggtatccata tgtttagcga
     5101 cacattctca ttaggtgttg cacttgtcgc atttatttat gctgaaaaga atgccacaac
     5161 tacaaaaaca tttggttata aacgtttcga agtactcgca gcgttattta acggtgtaac
     5221 gctttttgta ataagtattt tgattgtttt tgaagcgatt aaacgtttct ttgttccttc
     5281 tgaagttcaa tcaaaagaaa tgttaatcat tagtattatc ggtttaattg tcaatatcgt
     5341 tgttgcattc tttatgttta aaggcggcga cacttcacac aatttaaata tgcgtggtgc
     5401 ttttctacat gttatcggag acttattagg ttcagttggc gccattactg cagctatttt
     5461 aatttgggca tttggatgga caatcgccga tcctatcgca agtattttag tttccgttat
     5521 tattttaaaa agtgcttggg gtatcacaaa atcttcaatt aacattttaa tggaaggcac
     5581 accaagtgat gttgatatag atgaagttat aactactatt aaaaaggatt cacgaataca
     5641 aagtgtgcat gattgccatg tttggacaat ttcaaatgat atgaatgcat tgagttgtca
     5701 tgttgttgta gaccatacat tgacaatgaa agaatgtgaa ttattattag aaaacattga
     5761 gcatgattta ttacatttaa atattcacca tatgactatt caattagaaa cgcctaatca
     5821 caaacatgat gaatcgatta tatgttcagg aacacatagt cattcacata accatcatgc
     5881 tcatcatcac gcgcatgtac attaataatt ttaacctact gccattgcat cgattaaact
     5941 tttcaatggc agtaggtttt ttatgtcttt atggcgactt gtttggtctt tgatgatgca
     6001 atgtttatta acaaattttc aactattatt tcttacatta gtcatatttt tgacaattta
     6061 ctattataat tctctaactt tagtcacttt aattaatttt tattagatat taatatgaaa
     6121 ataacgtgtt ttttgttatt gtatttatat gaagaaaagg aggcaccact ttgtttactt
     6181 actttaaatc agcatttaaa aatgctaaac cacaattatt aataacattg atatatgcac
     6241 ttatagcatt tgctgtaatt gcagttgtat atttacttgc taatttccag cttgctaagt
     6301 atgcacaaac tattgcaatt tattcacaat ttgggcaaaa accaccagta gatgcatatt
     6361 taaaagttat cgctgtatta cttatagcag ctgtagtttc actgtttgtt ttagttcaaa
     6421 tttttatcgg aattacaaat gttatgaaac gagcaatgag tcatgaaaaa gtaaaattta
     6481 ccgatttatt tattgcattt aaaaaaggta attatttaaa gagcgttctg atcggtcttg
     6541 tatctatagc aatgattatc gttctttcac ttctgacatc attactatac aaattatttt
     6601 ctccagtatc agaaatgatt atgaattcag tacaatcatc atatgcagat agtacacacc
     6661 tgattggtat tgctattaca actcaaagca tcataatcat tgttgtttta ttgattaaag
     6721 caattattac ttggttattg ttaataccta ttttcaactt tatgactagt ttcgttgaat
     6781 caactaacga taaagtaaaa acacacttag ctaatggatt taaagcaatg aaaaatggtc
     6841 aaaaaacatt tttcaaattt ttcattggaa tactattatt aaacttaatt attattttat
     6901 ttaaaacacc tgttggttac ttgatttcat ttaatacgca atcactctct caaagtgttg
     6961 cagaaaatat cataagagtt tatacagtaa tgacaatcat tttattcgtt gttattcatg
     7021 caatcatttt aatgggtatc gttcaatatt acttaaaacg tggtcaaaaa attactaaag
     7081 ataaagtaaa aacagctgac aaggataaaa aagttgtcac tgaaccaaaa aatacaaaag
     7141 tagaaaatgg taaagtgaca acatctgttg aaacaaaaac agaaaaagca caagattcat
     7201 taaatgataa tacaacaaaa acgatgactt cagataaacc agaagacaat caaccaaaat
     7261 aaattttgga gccccttaca actttagttg ttaggggctc ttatgcatgc gcttagcgca
     7321 ggcgctccta cttttcaact ttagttgtta ggggcttctt tctaaaataa ctaagtgaat
     7381 tatctatata tgaagaggtc tccaatactt tttatataat tcgtgattac attctatact
     7441 tttaattgta ttttctgctg tatggaaagt tggttttatt aattctgatt atgttcagaa
     7501 ctacaattca taagaaaaat gtgttaaaat atatttgtag taagtagaag caaaagatga
     7561 aaatctttaa ctcttgaaac acaaaaaggg caacactcgg aaacatgtta ccctaatgag
     7621 cccgttaaaa agacggtgac cttatatttt atttaaaaat agccttcaaa atgccggtca
     7681 aagcgaatag aaggttattt tttatggtct tgagtactaa tcaatactaa accaatgatt
     7741 gttaatacaa ccatcagcat ttcaaaatca gacatgctag tcctttctag gagtaacaac
     7801 tataaccata ggcatcaccc ctttattaag agattagcca ccatctatcc aacttgctca
     7861 ataaatatta taacatgcac acttttaaac agtaattcat agtataagtt tttttatttc
     7921 ttaatcaact cgataaacag ttgagtgaca tacccttgtc taactagcta tttcttcccc
     7981 tgttatcgtt tgttcatcat ataaaaattt aatttctcat tttttattct ctgataaaga
     8041 agagcaccaa ccttttcggc tgatatgctc ccttcaaaat agacattgaa aaatgaaaac
     8101 tttgaaagag aaatcgtcag tctattattg ataagtatta tcctatcctc gaaaaattac
     8161 tttcagacac tagtgaacaa aaattttact ataagcgtat actttggcaa tattcgaagg
     8221 aaaaacatgg attaacctgt gcatattata catttagagc ttatatactt aaacatgatg
     8281 aatttactcc ttatattatg aaatgttatc aatagatgtc gcctaaagat acaacaagat
     8341 tcgagacaaa acctgatcat caagcacagt ttgactggaa agaaagcatt aactttaaaa
     8401 cgaaagataa tcaaaggatt ccactatata taggtgtgct actactttat tattctcgtt
     8461 ttataatcat gcataacaat gagtaaatca agtgatgcct tatttaattc attaacacaa
     8521 tcgtttgagc taatagaagg tgtatataat gaacttgtaa cggataactt gaaaatagtc
     8581 atgtataagc caagaaaaga aagtacaagt ggtcgaataa atcgtagatt taaataattc
     8641 gctgatggtt ttaaatttca agtaaaacct tgtatttccg gcctccctag aaaaagataa
     8701 agttgaatca ataacaaaaa tattagatga aattaatgct taccaagacg aattgcattt
     8761 ggaagagatt cctaagtttt tttaatctta atgaacgatt taactactaa gttcatacta
     8821 gtacaggtaa attgcctatt actgcctaag agaaagaaaa aattttctta caaccactac
     8881 agaatgtgaa tgtaaaaaac tcatataaag tgaaacatat cttacttatg gaatgaaatg
     8941 tttgattatc ccaaaatcac aaatgcgatt ttggagttgt taggggctct aacgcaaata
     9001 cacccctact taaaataacg gtagttgtta tagtatactt aaatgcataa accatataaa
     9061 aggtgatgct aatatgacat acggttcaat tgtagctata ctctgtgccc tatttgtgat
     9121 tttcttcatt ccatatatgg agaagaaaga caaaaagaag aagtaacact agtatctgga
     9181 ttactagcat acaaaggagc agtaagacat tttctaatag aaaataactt tactgctctt
     9241 tgtacattac tcatcaacta ttgtaaatta aataataaat aactacctat tttattaatc
     9301 agctaaaaaa tgctttgcta aatattttgc tgcgccatcc tcttcattcg tgtatgccgt
     9361 tacatctgaa gttaatgctt ggatttcagg gcgtgcattt ttcatagcaa ctgtataatg
     9421 accaaattca aacattgctc tatcattgtc gctatctcca ataactaacg tttcttcttg
     9481 atgaatacca aaatgtgcaa tcatttcttt aatgcctgta cctttatcag tttgataagc
     9541 cattgtttcc gcattaaatc ttgatgaatt tgaaacacta atctgtagtt gcacatgatt
     9601 ttgctttaat tcatctctaa atgctgttat tttttctaaa ttagaactga atagataaat
     9661 ttttgaatat tcaccttcag gaaacttagt tacccaatct atcttaccag caagcgcatc
     9721 ttgtcttgaa gaccattcac tatgacttac gccattaata ggatcttgac tacgaatcat
     9781 atctcgcatc catgtttcat cttcttttaa agaaactcta ttaccttcaa aaggaaatac
     9841 ctcataataa atttgttggc gcttagctaa attagtaatt tgttgcactt gagccaatga
     9901 taaaccatga ttgaagataa tttctccatc tacttctcca attgttccat ttgaactaat
     9961 gatgccatta accgcaaaat cttgaggtac aagttgatgt atttcagaat gcgaacgtcc
    10021 tgttgccaaa aatactttat atcctttctc tctcaattga ttaatgacat ctttcgtata
    10081 cgttgatgct tgattatttt catgtaaaat tgttccatcc atgtccaaaa atattgcttt
    10141 tacgttatcc atattgccct ccactgtcca ttttatctta attaaatttt gtcattatta
    10201 cttattattt gcaaaatatt tactctaaca ttgccataga aaatcgatta ttccatcttt
    10261 gaactgctac atttttctgg aaaaatcgtg acatgttttc agatgtcaaa atatcatcta
    10321 ttaatccttg ttgtacactt tccccatctt ttaatagcaa aattttagta aagttaccag
    10381 taatttcttc aataaagtgc gtcacataaa tcatcgcaag cgttggatat gaatctgaca
    10441 atgagtcaag tatattcaat agtgactcac gagcaataaa gtctaaacca gctgctggct
    10501 catctaaaat taaaacctga ggttgcccca ttaaagctcg tgcaatcatc actcgttgtt
    10561 tttcacctgt agataaataa ccaatatatt gttgcgcttt agcagatatt ccaactaatt
    10621 taagtaaatg atgtgcttca ttacgtacct catcatcaat atcttgataa acaccaattg
    10681 atttaaaagc accgcttatc accacatcga ttactctttc accctcttga aacttttcca
    10741 gtaaactatg agatacaaaa cctatatgtt gtcgtacagt ctctgcagaa taccctacct
    10801 tgcctggcat tttaccaaat agattaacac cgccagttgt cgcaggctca tatgcattta
    10861 atatatttaa tagcgttgtc ttaccagcac cattcaaccc atataatatc catttatcac
    10921 ctttagcaat ttgccaagaa atatttttta aaattgtttt tccttgcttc attcgcccaa
    10981 tttgatctaa ttgaattaac atgcgaggtc acccctttat tgctactcca tacttctcat
    11041 aaaatcatat taacataaca cccttaattg tcagactatt taaataaata aaacacttcc
    11101 tttttacgca tttctgccaa attaagatga agtaaaagct aagtcgacct aaaaaagcac
    11161 ccttctagtc gattaatcta aaagggtgcc atatacttta attttaatac atgattgatt
    11221 ctaaaaaagt gaattattct acagtaactg atttagcaag gttacgtggt ttatccacat
    11281 ctaaatctct gtgtaatgct gcataatatg aaatcaattg taatgcaact actgaaacta
    11341 atggtgtcaa taattcatgt acatgaggaa tgacataagt gtcgccttct ttttcaagac
    11401 cctccataga aataatacat ggatgtgcac cacgtgctac tacttcttta acgttaccac
    11461 gaattgataa attaacgttt tcttgagttg ctaaagcaac aactggtgtg ccatcttcga
    11521 ttaatgcaat cgtaccatgt ttaagttcgc caccagcaaa accttctgct tgaatgtaag
    11581 aaatttcttt aagttttaac gcaccttcta aacttacgtt atagtcaata gtacgtccga
    11641 taaagaatgc attgcgtgtt gtttctaaga aatctgttgc aatttgttcc ataattggtg
    11701 catcgtcaac aattacttct attgctgttg ttacttttgc taattctctc aataaatcaa
    11761 tatctgcttc acgaccgtgc tcttttgcaa cgatttgaga caagattgat aatactgcaa
    11821 tttgtgcagt atatgctttt gtagatgcaa ctgcgatttc aggacccgca tgtaataaca
    11881 atgtgtggtc tgcttcacgt gataaagttg aacctgcaac attagtgatt gttaatgatt
    11941 tatgacctaa tttattagtt tcaactaata ctgcacggct atctgctgtt tcacctgatt
    12001 gagaaatata aacgaacaat ggtttttcag ataataatgg catgttgtag acaaactctg
    12061 atgcaacgtg tacttcagtt ggtacgccag cccatttttc taaaaattct ttacctacta
    12121 aacctgcatg gtagcttgta cctgctgcaa taacgtaaat gcggtctgct tctttaacat
    12181 cattgatgat gtcttgatca attttcaagt taccttctgc atcttgatat tcttgaataa
    12241 tacgacgcat tactgctggt tgttcatgaa tttcttttaa catgtagtgt gcataaacac
    12301 ctttttcagc atctgatgca tcaatttcag caatatatga atcacgttct acaacgtttc
    12361 catctgcatc tttaataata acttcatctt ttttaacaat aacgatttca tggtcatgga
    12421 tttctttata ttcgcttgtc acttgtaaca ttgcaagtgc gtctgatgcg ataacattga
    12481 aaccttcacc aacacctaat aataatggtg atttattttt agcaacatag attgtgtctt
    12541 tgtcttcagc atctaataaa cctaatgcat atgaaccatg taataatgac acaacttttg
    12601 taaatgcttc ttcagttgaa agtccttgat ttgaaaagta ttcaactaat tgaacgataa
    12661 cttctgtatc tgtttctgaa atgaatgata caccttgtaa gtattcacct tttaactctt
    12721 catagttttc aataacaccg ttatgaacta gagtaaaacg gccatttgat gattgatgtg
    12781 gatgagagtt ttcatgattc ggtacaccgt gtgttgccca acgtgtgtga ccgattccaa
    12841 caggtccatc aaaatcgcta ctatcagcaa ctttacgtaa ttctgcaata cgaccttttt
    12901 ctttaaatac agttgtatta tcatcattta ctaccgcgat acctgcagag tcataacctc
    12961 tgtattctaa tttttctaaa ccttttaata ataattcttt ggcattatca tagccaatat
    13021 aaccaacaat tccacacata acgacatttt cctccatatt ggaatagtac gcgtaaatta
    13081 tgatttattg ccgataattt agattgacaa tctgctttca taatataaat aggaacatgc
    13141 tattatcgca ttcatccata acaaattaag catagttatt tttacaacta tacaaattgc
    13201 tcacactgta ctttccatat taatattttt tatattcaat ttctggcgat cttattaact
    13261 ttgtccatta agtcacccta atgttttact taataagcta acgaatgagc cacatccggg
    13321 atagcatccg ccgatctatt cgatcactat cctcctcgtc tacaaataca tatattgcac
    13381 tctataaagg ccactcatat attaaccttt aatcttcaaa tacaaatatt tatttgcaca
    13441 ggcgctttaa ctgtactgcc gaactttccc cctttccatt aatcattatt gtacaacggt
    13501 gttgttttgt tttgcaaata ttttcacaat aaaattttaa aaatcctaaa acaatttttt
    13561 tgttttactt tttcaaaata tctatactgt cacattgatg acactttatt taattttgtc
    13621 acatttattt tgacaaagtt gatttttgtt tatattgagt aacaagtaac gtctctatac
    13681 actatatata gtcacatata ttaaaaaaga ggtgtaaata tgtcgcaaac tgaagagaaa
    13741 aaaggaattg gtcgtcgcgt tcaagcattc ggatcatttt tgagtagtat gattatgcca
    13801 aacattggtg cattcatcgc ttggggtttc atcgcggcca tttttataga taatggatgg
    13861 ttacctaaca aagatttagc tactttagca ggaccaatga ttacttattt aatcccatta
    13921 ttgatcgcat ttagtggtgg tcgtttaatt tatgatttac gtggtggtat catcgcagca
    13981 acagcaacta tgggggtcat cgttgcatta cctgatacac caatgttact tggtgcaatg
    14041 attatgggtc cacttgttgg ttggttaatg aagaagaccg accaattgat tcaacctaga
    14101 acgccacaag gttttgaaat gttatttaat aacttttctg ctggtatttt aggatttatc
    14161 atgacgattg caggatttaa aattttagca ccacttatga aatttattat gcatatttta
    14221 tcagtggcag ttgaagcatt agtacatgca cacctacttc cacttgtaag tattttagta
    14281 gagcctgcaa aaattgtatt tttaaacaat gcgattaacc atggtgtatt cacaccgctt
    14341 ggtgcagatc aagctgcaaa agctggtcaa tcaattttat acacaattga atctaaccct
    14401 ggaccaggtt taggtatctt acttgcttat atgatttttg gaaaaggcac tgcaaaagca
    14461 acgtcatatg gtgctggaat tatccacttc ttaggtggta ttcatgaaat ttatttccca
    14521 tatgtattaa tgcgtccttt attatttatc gctgttattt taggtggaat gactggtgtt
    14581 gcaacttatc aagcaacagg atttggattt aaaagtcccg cgtcaccagg ttcatttata
    14641 gtttactgtt taaatgcacc tagaggtgaa ttcttgcaca tgttgctcgg tgtcttcctt
    14701 gctgcacttg tatcattcgt tgtagctgct ttaattatga agttcactag agaaccaaag
    14761 caggatttag aagctgcgac agctcaaatg gaaaatacta aagggaaaaa atcaagcgtt
    14821 gcttctaagt tagtatcttc tgataaaaat gttaatacag aagaaaatgc tagtggtaat
    14881 gttagtgaaa catcttcatc agatgatgat cctgaagcgc tattggataa ttacaacact
    14941 gaagatgttg atgcacacaa ttacaataat ataaatcatg ttatttttgc ctgcgatgcg
    15001 ggtatgggtt ctagtgcaat gggtgcaagc atgttacgta ataaatttaa aaaggcgggc
    15061 attaatgata ttacagttac aaatactgcg attaatcaat tgccaaaaga tgctcaatta
    15121 gttatcactc agaaaaaact aactgatcgt gctattaaac aaacaccaaa tgccatccat
    15181 atttcagtgg ataatttcct taattcacca agatatgaag aacttttaaa taatctaaaa
    15241 aaagatgatc aagcataata attaaataaa ttaaaaaatg gaggataccg ccatgttatt
    15301 gagtacacgt gaaaaagaaa tgatagccct attgattaag taccacagtc aatatatcac
    15361 tatacacgac attgctcagc aacttgcggt gtcctctcgt actattcacc gtgaattaaa
    15421 aggtgttgaa gcatatttaa cttcattttc attaacttta gaacgcgcaa acaaaaaagg
    15481 gctacgcatt gctggcgcag attctgattt aaacgatttg aagcaatcga ttgcacaaca
    15541 tcaaaccatt gacttatctg ttgaagagca gaaagtaatt attatatacg ctttgataca
    15601 agccaaggag ccagttaaac aatatagttt agcgcaagaa attggcgttt ctgtccagac
    15661 tttagcaaag atgttagatg atttagagct tgatttaaat aagtaccaac tatctttatc
    15721 tcgaaagcgt ggcgaaggca tttacttggt aggtactgaa tcaaagaaac gtgaattttt
    15781 aagtcaatta atggtgaata acttaaatag tactagcgtt tattcagtaa ttgaaaatca
    15841 ttttgtcttt cattcattaa atcaaatcca caaagacttt gttgacttag agcgcatttt
    15901 taatgttgaa agactattaa tggactacct aagtgcctta ccctaccaac ttaccgaatc
    15961 aagttattta actttaactg tccatatcgt gctatccatt tcacgtataa aaaatggaga
    16021 gtatgtcgca ttaaacgatg atatttatga ttctgtacaa aacacatttg aacacaaagt
    16081 agcaagcgaa cttgctgata aacttggtca aatatatgac gtcacgttta atcaggcaga
    16141 aattgctttc attactatcc atttacgtgg agctaaacga aaaaatctta atgatacatc
    16201 attaaataat cgttgtgaag aaaacaaaat taaagcgttt gttaacaaag tagaaatgat
    16261 ttccggtatg acatttgcag atttggatac tttagtagat ggactgacgc tacaccttaa
    16321 tcctgcaatc aatcgtttgc aagctaatat cgagacctat aatccgttaa cagacatgat
    16381 taagttcaaa tatccaagac tatttgaaaa tgtaagatta gctttaaatg attgttggcc
    16441 tgatttgatt tttccagaga gtgaaattgc ttttatagtt ttacactttg gtggctcgat
    16501 taaaaaccaa ggtaatcgat ttttaaacat attagtcgtt tgcagcagtg gtatgggaac
    16561 tagtcgtcta ttatcaactc gtctagagca agtttttagt gagattgagc gtattacaca
    16621 agcatcagtc agcgatttga agtcactaga tttaagtcaa aatgatggca ttatttctac
    16681 tgtgaattta gacatcgact ccccctattt aacggtaaac ccattattac cagatagtga
    16741 tatcagttat gtcgcacagt ttttaaatac aaagtctacg ttccaagaga cgcatgataa
    16801 atcatcaaac atgattgata aggatgatgt tcatgttgaa acgaaagatg ttgatggcaa
    16861 cacatctttt gaaaatgaac aaacttcata cttaacttca gttttcgaaa aacatttaag
    16921 tgacgaaaaa ttagaacaat tattgcatca tatgcgttcg ggtttaactt tgcttgattc
    16981 agtgaaaata gttagtaccg aagttaaaca gtggcaaaca tatatcgcag attatctata
    17041 tcaatgcgat gtaataaacg atccaacgtc attcgctgaa ctactagagc aacgattgat
    17101 tgacaatcca ggatggatat taagtccata tcctgttgca ataccacacc taagagacaa
    17161 tatgattaaa caccctatga ttctaatcac agttttagaa gaaccgttaa cattgcctag
    17221 tattcaaaat gacaatcaaa caattaaata tatgatttcc atgtttattc ctgacaatga
    17281 ttttatggca tcactggtaa gtgacttgtc cgaattttta agtttgaaat tagaatctat
    17341 tgatactttt atggaaaatc cacaggaact tgaaacatta ttaagaaaca aatttttaga
    17401 acgaattaaa aaacaattta tttaggagtg tacaaaatga gcgaattatt tagtaatgac
    17461 aatatctttt taaatgtaaa tgttaacagc caaaatgaag caattgaaaa agcaggtaaa
    17521 gccttagttg atagtggtgc tgtaacagat gcttatattc aagcaatgaa agatcgtgag
    17581 caagttgtat caacatttat gggaaatggc ttagcaattc ctcatggcac agatgaagct
    17641 aaaacaaatg tgattcactc aggtttaaca ttattacaaa tccctgaagg cgttgactgg
    17701 gatggcgaag tagttaaagt tgtagtggga atcgctggta aagatggcga acatttagac
    17761 ttgttatcta aaattgcaat tacatttagc gaagaagaaa atgtggatcg tatcgttcaa
    17821 gcaaaatctg cagaagaaat taaacaagta ttcgaggagg cagatgcata atgaaagcag
    17881 ttcactttgg tgctggtaac ataggtcgtg gtttcattgg ttatattctt gcagacaaca
    17941 atgttaaagt aacatttgca gacgtcaatg aagaaatcat taatgcttta gctcatgatc
    18001 atcaatacga tgttatttta gctgatgagt ctaaaacaac gacgcgcgtg aataatgttg
    18061 atgcaattaa ttcaatgcaa ccttctgaag cgttgaaaca agcaattcta gaagctgata
    18121 ttattacaac agctgttggt gttaacatac tacctattat tgctaaatct tttgcgcctt
    18181 tcttaaaaga aaaaacaaac catgttaata ttgttgcttg tgagaatgct attatggcaa
    18241 ctgatacatt gaaaaaagca gtacttgata ttactggccc tcttggtaac aatattcatt
    18301 ttgctaactc agcagttgat agaattgtac cattacaaaa gaatgaaaat atattagacg
    18361 ttatggttga gccattttac gaatgggttg ttgaaaaaga tgcatggtat ggtccagaac
    18421 taaaccatat taaatatgtt gatgatttaa caccatatat tgagcgtaaa ttattaactg
    18481 tgaatacagg acatgcatat ttagcgtatg ctggtagatt tgcaggtaaa gctaccgtat
    18541 tagacgctgt aaaagatagt tcaattgaag ctggcttacg ccgtgtttta gctgaaacaa
    18601 gtcaatatat tactaatgaa tttgatttta ctgaagcgga acaagctggt tatgttgaaa
    18661 aaataataga ccgtttcaac aattcttatt tatctgatga agtgacacgt gtcggacgag
    18721 gtacgttacg taaaattggc cctaaagata gaattataaa accattaaca tatctttata
    18781 ataaagattt agaacgcact ggtttattaa atacagctgc attgttattg aagtatgatg
    18841 atacagcaga ccaagaaact gttgagaaaa ataattacat taaagaacac ggtttaaaag
    18901 cgtttttaag cgaatatgct aaagttgacg atggcttagc cgatgaaata attgaagcgt
    18961 acaattcact ttcataattt attgagcttt gtttgaaaca agaagtttcc aacgttattc
    19021 gttaacaatc agtaataatg tagtagttcc gttgaattaa caatattaaa tttctgaaca
    19081 taaaaaatac tcccttcaac atagacactt aacttgtgtt atgtatgaaa ggagtatttt
    19141 tgcgttaata atttgtttta ttttcgagcc acagcgacct attcaattgc tattggtcat
    19201 tactaaaaca aattcatatt aactgttaga cttggttact tagtaaggaa tatttcccta
    19261 tgaaataact agatgttcac attcttgaat aaattttatt cttcagtttg ttggtctttc
    19321 ttagtgaatc ttctaattaa gaatgccata cctgcaccta gagctaattc agcatatggt
    19381 aaatcgtcat tatgtgacat accagtatct ggtaaagttt tagcttgttg tttaggctta
    19441 ttaacttttc cttgttggtc tgattttgca tttgctttgt tttcttcagg cttagttaca
    19501 ttaagcatat cttgatgcat actatgacta ccatttgaaa ctgttgctgg agatgcattg
    19561 gcaccgtcgt tttgcgtagc tttattgttt gcagctgaac caactgattt ttgcgtatca
    19621 ttagtttgca tatctttagc tttattgttt gcaactgggc caactgattt ttgcgtatca
    19681 ttagtatctg ctgttgccgt atcatctttt tggctaacat tagttgaagt cattttatct
    19741 tttgcttcag aagatgcaga tgttgatggt ttattcgaaa cttcagtatc agctttgctt
    19801 ggcgatttat ctgcttcgtt agatgcaacg ttagtttcag acttaagttg tcctgcatca
    19861 gtttgatttg tcgtactttc ttctttatct tttgatgtat tagaaggtac atttggttct
    19921 gttatgtctg ctgaaggcaa tgtttcagtt gttgattcaa ccatactttg atttgttgaa
    19981 tctctaccat ctttttctgc cttagcttta ttttcagatt ttggttgtgc aaccttgcca
    20041 ttagttgatt gagattcagc actattattt acttcagcat tttgttttga atcatttaca
    20101 gatgcattat ctttactatc agcagatgat gctgcttctg tgctcgcagt tgttggagcc
    20161 gttgctgttg atcctgttgg tgcattctcg tttgttgctg tagttgtact attgttattt
    20221 gttgtgcttt ctgctggcgt tgcattatct gtttctgtta caggtttatc agttgtgccg
    20281 ttattagttg attctacttc tggtttacta gttacatcgt tatccattgt cggactgttt
    20341 gttgatgcat ctgcactaga attgttatta gcttgcggtt tatcctttgc atcatcagtt
    20401 gctgatgtta ctgttgtttc acctgttgcc gcatcactat tatttggtgt tgtcggagaa
    20461 gcgtctgctt tgccattatc tgtcgtctca gatacgttag gttgtccagt gttttctggt
    20521 gttgcattag catttgaatt tgctgttgca tcattattat ctgtaccatt attagtatca
    20581 ttagcatctg gatcattctg aggcacaatc gcttcaattg caggtatcgt tacattttgt
    20641 aattcagcaa cctctgtatt tgtttgtgtt ttatctaatt tatcagcaaa tctgtcaaaa
    20701 tatctaccta aatctgtacg tgcaatttct ttcgccgatg catctgcatc tgcattttta
    20761 attatttcta tttgcttgtt aaccacttct ctaattgctt ccaaagcatt tttcttaact
    20821 actggattaa tacgttgtgc tttaagttgt tcaagcgcac tatttttgac agtagcgatt
    20881 tctgcatttg tagtttgatc agaaatatct tcagttgctt ttgataaaat gtcttctaaa
    20941 gcattcgtaa acgcttcttt ttcttcagtt gtagcatcag cgtcgacatt tacacctgct
    21001 tcaatctggt ctagtgcagt ttctaattct tcgatagctt tttgtttttc tgttgagtca
    21061 atttgaatgt tatcaaatgc ctcaagtcct tgagctttcg ctttttcaac ttcagcagtt
    21121 gttgttgcat cagtaatacc ttgtttagct tgatctgtaa tttgtttaat cattgctaat
    21181 gcttcagttt tttcttcagc agttaactgg tcactatgat caattgattc tttcgtatct
    21241 tctgctttag cttcaatagc ttggttcgct ttaggtttaa cagtagcatc tacttgaata
    21301 gtatcaattg ctgctttacc ttgtgttaat gcatcatcaa cgtcaccatt atccacacca
    21361 ttattaatgt tttctaatgc agtttgaaca ttttggtcaa cttgcttaat tgcttgttgc
    21421 ttttcatctt gtgttgcatt agtgtcagct gaaatattat ttttcttctg atctgcataa
    21481 gcatataaat ctgttgtagc tgattctttt ttacctgttg gaattgtgta atcgttaata
    21541 ttatctaagt cattatgaat ttgaacttca atgtcatctt tagaagtagc ttgattaaca
    21601 ttttgatccg cagtttgttt taattcagca agtttttgtt tcgcttcagc aatttcactt
    21661 gaagtcgatg cgttagagtt atccgcttcg tttactttag cattatatgc atcttcaatt
    21721 ttagctaaag catctttttt gtactcacta aatgttttaa ctgcattaat tttagctttt
    21781 ccttctttaa ctgcattatc aacatattca tttgttgatg attgatcgac atttgttttc
    21841 gcttgattta attcagtatc aacttcttgt tttgcatcat taatttcttg ttgtgatgca
    21901 tttggtgttt gttctatttg tgttttctta tcagctgcag cttgatctaa ttctttttta
    21961 cctgctggtt tcttaacagg atttgcatga agttgttgaa ctttttgtac tgctgtatct
    22021 ttagcagtag ttacatcacc tgtagtagtt gctgcattaa tattatttaa accttcttca
    22081 tatgctgctc taactggtcc aatatcgtta cctttttctt cattagtagt ctcattatta
    22141 ttaagtattt cagttatttt attttgcatt tcagttagca attctgctct tgcattcgtt
    22201 ttaacatctg ttgatgcttg aattgggtca attgcttgaa ttgcattatc ttttgcagtg
    22261 tttacatcat cgattgactg tgcattttca atattttgat taccttgtgt taattgtgcg
    22321 tctacttgtt gatttgcttg ttctttttct tcagtagtcg catctgcagt ttgtgcaata
    22381 agcgcttttt gttcgtttgc ttttgttgct aattcatctt tcgcaacatc tttaattgtt
    22441 gtatctgcag taataccttg aatatcagca actgcttgat ctttaatttg cgtaacatca
    22501 ttagttgttt gtgcatttaa gatatcttga tacgcttttt ctttagcttt taaaactaaa
    22561 tcttttgctg catttttctc ttcagttgta gcgccagttg tattatcaat tgcttgattt
    22621 tgagttgtca cagcttgatc aacttcattt ttcgcattcg atttaactgc tgttgctggt
    22681 tgtgtgcttt gaattgaatt ctttccagcg tctttcgctg tatctacacc attatcatca
    22741 gttgcagctg taatattatt tttcgcgtct gtaactgctg ttgctaattg ttgaatagct
    22801 gcttcttttt cttcatttgt agcgttctga tcattattga taacatttgt ttgcgttgct
    22861 tgtaattgat caatctcatc tttagccgct tgtttcttaa caacttttgg tgttaccgca
    22921 ttaattgctg cttctgcatt agctttcgct tcatcaactt gtgcgttagt agttgctgct
    22981 gaaatggctt gatttgcttt accattttca gtatttgctt ctgcatcagc tgcttgtttt
    23041 tcttcatctg ttgcatctgg tgtagcttga atctcttgca atttgttatt taaaattgct
    23101 gtgatttcat tacgtgcagt tgctttttta ttaactgttg gtgttacttg atcaatacta
    23161 gtttcacctg tcgttttcgc ttggtctaca tcattttgac tattagcagc ttcaatgttg
    23221 ctatttgctt gtgtcacagc attatctacg tccgcattag ccgctgcaat ttcttcagca
    23281 gtaatatctt gcgtttgagc gattgctgtt ttacgttcat tcgctttcgt agcaattgct
    23341 tgtttcgcat tatctttagt tgttgttgct ggctgaatcg cttcaatttt agcaatttct
    23401 gcatttttag ccgcttcaac ttccacattt gaatgagctg catctattgc tgcatcagca
    23461 gccgtttttt cagtttgaac ttgttgttta gcagcttctt tttcttctgt tgttgaaccg
    23521 ttattagcat caattgctgt ttcttgagct tgtactttat ctgcaattgc ttgttttgct
    23581 gctggtttaa catttgcatc tggcgtaatt gcagctattg tagcttcatt agtagttttt
    23641 gcattatcta catctgtatt tgctgtagca ttatctatat cagcgtttgc agtaactact
    23701 gcttgatcaa ctttatcttt tgcagcttgt tgttcttcag tagtcgaatc attcattgct
    23761 tcaattgcag ttttacgttc acttgctttt tgagcgattt ccgctttagc atccgatttc
    23821 ttagttgtgg cagcttgcac ttgattaatt gcagcaatac cattgtcttt agctgttgtt
    23881 acatcactgt ttgtatttgc agcatcaaga tttgttcttg cttcttgctt tttagcatct
    23941 aattctgtat atgcagcttc tttttcttct gtagttgaag cattgctatt ttggatttct
    24001 tgtttacgtg tattatatgc gttttctact tctgtatcag ctgcaggttt aacttttgct
    24061 tgtgtttgaa ttgcattgat tttatctaat acttttgctt tagtatcagc cacttcttgt
    24121 tgtgatttaa caacttggat gtcatgtaaa ccttctgttt gagctgcatc tactgctgca
    24181 tttgcctctg ctacttcttc atcagttgca tttgaaactg tagcattttg cgcttttcta
    24241 gctgtagctg cttgtctaac ttctttataa gcatccattt tagtttgagt tgaatccgta
    24301 atattctcaa ttttgaatat ttcttcgttt ttaacgcgtt ctaaatcttg tgcagtcgtt
    24361 gtcgcttcaa ttgctttaac accagaaact ttagctgcat taatacgttc aatagcttcc
    24421 gctacttctt catttgttgt atcaggattt aaaggtgctt gatcaatttg tgcttgaaca
    24481 acttcgtcaa attcttcaag agctgctgct ttagctgttg tagcaggtgt agtttgatta
    24541 atatcattga ttgcttttgt tttaatggct tctacttgtg catttgttgt tgctgcatca
    24601 atatctttaa ttgcctttgt ttcaatttta ccaattttat catttgctac atctttttca
    24661 tcttgtaatg atgcatttga ctttttaatt tgttgtttac gagttgtaac tgcttggata
    24721 atatcttgtt tcgcttgagg tttaactgtt ggtgtaatca catcttgttc taacactgcg
    24781 ataccattat ctttttcagt tgtgacacct tgtgatgttg tttgtttatt aatttctgcg
    24841 attgcattat ttttatcatt gttaatttta gtcacaagcg ctgcaacttc atcttgcgta
    24901 acttttttac tttgttgtgc tgctgtaacc ttttcttgag ctttagtatc taattcagca
    24961 attgctgctt gattatcaat taatgcagct tgtaatttag ttactaaacc gtcaatatcc
    25021 gcttgagatg cacgatttgc agtttcaacg tgattcgcat cttcatttaa aatagtgtct
    25081 gcttgttgtt taagtttatt gtattctgca attgatgctg ttgtgtaatg actattatca
    25141 acttgtgagt ttacttgttg ttgcaacgca tctttgttca tttcaaccgc tactgaaaat
    25201 ggatctgcag ttagtgtaac ttctggttgc gcattattaa ttacaacatc tgaagcagta
    25261 cgatatgtta atttttcatt aaaatcaata tttttaggtg tatcgatatt cgcaacatta
    25321 actttatatg ataattttaa agatttatct gggaataaaa cttctttagt gtgtgtacca
    25381 cgtgccgttg tcacaccttg gcttgtaaat gtaactttat ttgcagtttg atcataatta
    25441 acagtcatat ttttcaatac tgtactgtct tcattaccat tagggaatgt tgtagttaat
    25501 gaatcattaa cgtaagttac accttgtggt aatgttactt catatttaaa ttgatctgct
    25561 tttaatgaag caccaaaatt accattgtta ccgatttcag tattaatagt atattcttta
    25621 ttgttagttg ctttcggtgc taaatctcta tttttgacat ataaatgtga tcctgagaat
    25681 agacctacat tatcaatgaa tgaatagtat ttataaccat ctttatttgt tgtaattctt
    25741 gaagcatcag caactgctgt attgtcagga ataaattgta aatctaaacg atcagcatca
    25801 gttggtactt taaataaatg tgcagtacca gtcttagcaa catttacagt tgctaattca
    25861 gtatttttct tagcatcttt aataactaaa tttgttgcac cttgcttact attcgtttgc
    25921 atagtagtaa agttaataat taattctgaa tctggtttta catttacagt ttttgtaata
    25981 ccgttaaagt taccatgatc tgtagaatca tttgcattca cacgacctaa tgcagccacg
    26041 tttcctttag cttgatagtt ttgagggtta ttcttatcaa acatatcgct tcgtcttaat
    26101 tctgagttaa cgaaaccaat cttaccgttg ttaattaatg aataaccatt tactttatct
    26161 gtaacagtta cagttggatc ctgtctattc tcatctgttg atatggcagg atcatcaaat
    26221 gttaatgtcg tattaatact gccttcacca gtattgctag catttggatc ttgagtttgt
    26281 gcgtttgctg ctacaggtgc tgctggttgc gctgctgctg gagcattcgc tggctgtgtt
    26341 tgatttgccg gtgttgcatt attattaggt gttgcttggt tatttccttg acctgcttgg
    26401 tttgccggtg ctgcttgatt tccaggttgt gcttgtgcag cgttattcgg atcagcttga
    26461 ttaccttgtc cagctggttg tgctgctcct cctgctggat tagcctgtcc accttggttt
    26521 gctggctgtg ctgcaggatt agcttgagca ccagcatttg cgttaggctg tgtattggca
    26581 tcagctggtt gtgctggttg attttgtgca ggctgatttt gctctgctgc agacgctgtt
    26641 gtcgggttag tagatataaa agtaacagtg gcaattaaag ctgaaaaaat accgacatta
    26701 aattttctga tactaaattt ttgttgtctg aataaattca ttaagtcatc ctcctggttg
    26761 attattctcg ctgttaaatg atttcactta atcaactgtt aagataagta gtagcatctg
    26821 cgttaaaaac acaaagcaac tctatctaat taaaattaat tttatcatca ttatatattg
    26881 agtaccagtg tattttatat tacatattga ttactttgtt tttattttgt ttatatcatt
    26941 ttacgtttgt actataaatt atttctagaa acacaaaaaa accgatgcat acgcatcggc
    27001 ttatttgtaa tacagtattt atttatctaa tcccatttta tcttgaacca catcagctat
    27061 ttgttgtgca aatctttcag catcttcatc agttgctgct tcaaccatga cacgaactaa
    27121 tggttctgtt ccagaaggtc ttactaaaat tcgaccttct ccattcattt ctacttctac
    27181 tttagtcata acttctttaa cgtcaacatt ttcttcaaca cgatatttat ctgttacgcg
    27241 tacgttaatt aatgattgtg gatatttttt catttgtcca gctaattcac ttagtgattt
    27301 accagtcatt tttattacag aagctaattg aataccagtt aataaaccat caccagttgt
    27361 attgtaatcc atcataacga tatgcccaga ttgttctcca cctaagttat aattaccgcg
    27421 acgcatttct tctactacat atctgtcgcc aactttagtt ttattagatt taattccttc
    27481 ttgttcaagc gctttgtaaa aacctaaatt actcataaca gtagaaacaa tcatgtcatt
    27541 attcaattct tgatttttat gcatttcttg accaataata aacataattt ggtcaccgtc
    27601 aacgatttga ccattctcat ctactgctat gattctgtct ccatcgccgt caaatgctaa
    27661 cccaaaatca ctttcagttt caactacttt ttcagctaat ttttcaggat gtgtagagcc
    27721 acatttctca ttgatattat atccatcagg actacatcca attgtttcag tatctgcttc
    27781 taaatcacca aataagaatg gcgctagtga tgatgttgaa ccatttgcac catctaaaac
    27841 aattttcaaa ccttcaaagt taacatctac tgttgatttt aaatagctca aatatttttg
    27901 tgccccttca aagtaatctg aataatgtac aatatcattg ccaactggtc ttggtaattc
    27961 tggattttct tgatccaata atgcttcaat ttcattttct tgttcatctg atagtttaaa
    28021 accatctgat ccaaagaatt taataccatt atctgcaact ggattatgag aggctgaaat
    28081 cattacacct aactctgcac ccatatcgcg tgttaaatat gcaacacctg gtgttgaaat
    28141 aatacctaat cgcatcactt ctgcaccaat tgaaatcaaa ccagctatta atgctgattc
    28201 taacatttca cctgaaactc tagtatcgcg acctacaagt acacgtgggt gtttttcacc
    28261 tttattatgt gctagaacat agccaccgta tcttcctaat ttaaatgcca attcaggtgt
    28321 tagttcttgg tttgcgacac ctcttactcc gtctgtacca aaatattttc ccattgttta
    28381 ctctccttta atttagctat ttattttaca tttatataag ccttcgtttc acttggttgt
    28441 gctttagtga catgttctgg taaattgatt tttacagtct tttcagttga ttctgaaata
    28501 ccatctaaat ctacttctgc atcaacttcg cttatatttt gtaagtcatc tcgactaccg
    28561 aagatttcaa tttctttatc ttctaaatca atcgaactta actctttatc atctgctaaa
    28621 ctacctttct gtttaacatt tactttaacc tttttgctaa aaggctctac tttaacttgt
    28681 aaattcactt cattaggttg aatcgataca tttaatttat tcagtttttt atcaaaagcc
    28741 gttacttctg cgacatcttt tgtgtcacca ttaatctttt tattagtttt aaaagtggct
    28801 tttaaataag cgatatcatt caattgttct tctccacctg ttactttaac tgtttgtggt
    28861 gaaacttctt gctttgtaat tttataaagt ggatcaatat cactctgact tacatcaggt
    28921 tgaactgtca tctttttagt tactttgttt tcaagcgtaa tatttgctaa tttaggtttt
    28981 acagaataat gaatgtcatc agctaaccct ttaacttgat acttctcttg atattttcca
    29041 gctttagcat ttgataaatc aatcactact cttaaatctt ctggattttc aatttttatt
    29101 atctttgatt gtggtcctga aatagtcaca ttaactgttt caggcgcttt tgttaaatgc
    29161 aaatctttag tgttataaag aatttcaacg ggtacatctt gaatcgtttt actagacttt
    29221 tgaccaagat taccagtgtt aaagatattt ccaaaaacat tgttaacaga taaaaagaaa
    29281 aacaatgcca aaagaaaggc aataaatctc aagccccatt tactttctag catattattt
    29341 cacacctttc ttttgaaagc gtgtgccaaa ccaatgttca gcaagcaact cttcaaaaat
    29401 ttcgtttgaa atgtctcgtc gtaattttcc atcaaatgtt accgaaatat caccagtttc
    29461 ttcagataca ataacggtaa atgcatcaga tacttctgaa ataccaaccg cagctctatg
    29521 tcttgtaccc aaacttttag atatcttagg actatcagac aatggcaaat aacttgctgc
    29581 tgctgcaatc ttagtgcctt gaataatcat tgcaccatca tgtaaaggtg tgttaggtat
    29641 aaagacatta attaaaagtt cttgcgaaat atttgaatcc attgcaatac ctgtttcaat
    29701 ataatcttga agacctgttt ctttttcaaa gacaattaat gcacctatac gtcttttagc
    29761 catatattgc acagcctttg aaaccgattg aatcaatttc tcttcatctt tactatacgt
    29821 attagaagta tagcgtttta aaaagctacc tctaccaagt tgttctaacg cacgtctaat
    29881 ttctggttgg aatattacta ttaaagctaa taccccccat tgaataacga tatcgaataa
    29941 tttagatgtt gcagtcaagt tcaatatcat acttatctgc tgaccaataa caattactaa
    30001 tatcccttta agtaattgta tcgctttagt tcccttaaag accgtgatga gaagataaag
    30061 tacataccaa actatcagta aatcaaggat actcgttaca atttttaacg tactgaggtt
    30121 ttgaaaaaag ttggaaaaat ccataacatc tcctccgggt aatatttttc cataataccc
    30181 attataccaa tcatttacat cactgtcata cgaacatata tttaaataga aaaaatttat
    30241 tttaaagatt ataactactc ttaatcattt tagtgaatta aaaaaagtag tgcaaaaagc
    30301 aaaatatact ttatacacta caaatcattt atttataata aagtttcacc aaaaaatgtt
    30361 ccaactaatg aaaccgcttg ttcagcagta tgattattac tgtcaatcaa tggatttact
    30421 tcaactaaat ccattgagga aattaaatgt gattgatgca gtaattccaa tgcaaaatgg
    30481 ctttctctat aactaagacc acccaaaact ctagtaccag tgcctggcgt ttcaagcgga
    30541 tctaaagcat caacatctaa agataaatga acgccatcaa cattgcgtga cttcaaatat
    30601 tctattgtat tttcaattac ttcctttatc cctaatttat caatatctga catagtaaat
    30661 gttttaatat tatgatcttt gataaattgt ctttcacctt tatctaaatc tctcatacca
    30721 attagtacga tgttttctgg cttgattaca ttactattta attctaaaag ttctttggga
    30781 ccttcgcctg tcaaaatcct tagaggcata ccatgaatat ttccacttgg tgactcttca
    30841 ggtatattta aatcaccatg tgcatcatac caaataacac ctaaattatt ataatgttta
    30901 cttattgctg atactgaacc taccgcaata gaatgatcac caccaagaac tagaggaaat
    30961 ctgttatttt caattgatgc tgaaacctct ttatttaatt tttgattaac atctataatt
    31021 tcatcataat ttcttaatcc tttttgttca ctatgaaatt tttcaatgtt cacagcaggt
    31081 accttaatat cccccttgtc atatacatca aggtctaatt gctttaatct tgaaattaat
    31141 ccagcatatc taattgctgt tggtcctaaa tcaacaccta attttctttg tccaaatgtt
    31201 gatggtgcac ctataatatc aattgctttt gtctttgtca taagcgtccc cctttgctct
    31261 atgtaattaa agaataatgt atgcgcttac cattatcaag caatagctac acatataatc
    31321 tgtttatctt attacttcat aaaaaaaagc acttcccaaa aatggaaagt gcaagtagtg
    31381 agccatagag gattcgaacc tctgaccctc tgattaaaag tcagatgctc taccaactga
    31441 gctaatggct ctaatggctg ggctagctgg attcgaacca acgagtgacg gagtcaaagt
    31501 ccgttgcctt accgcttggc tatagcccaa tatatagatg gtggaggggg gcagattcga
    31561 actgccgaac ccgaaggagc ggatttacag tccgccgcgt ttagccactt cgctacccct
    31621 ccagcttatt catataattt aataatcaaa atggtggaga atgacgggtt cgaaccgccg
    31681 accctctgct tgtaaggcag atgctctccc agctgagcta attctccaaa ataatgactc
    31741 ctacgggact cgaacccgtg ttaccgccgt gaaagggcgg tgtcttaacc gcttgaccaa
    31801 ggagccatgg ctccacaggt aggactcgaa cctacgaccg atcggttaac agccgatagc
    31861 tctaccactg agctactgtg gattaatatt
//
LOCUS       DAPDIM010000032        30442 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000032 DAPDIM010000000
VERSION     DAPDIM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 30442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30442
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.032"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            194..1384
                     /locus_tag="RFE25_001487"
     CDS             194..1384
                     /locus_tag="RFE25_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="HDU2816550.1"
                     /translation="MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMD
                     MLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALP
                     MNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
                     YGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDE
                     HNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDV
                     FTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEV
                     RGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIR
                     HVFQ"
     gene            1493..2737
                     /locus_tag="RFE25_001488"
     CDS             1493..2737
                     /locus_tag="RFE25_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="HDU2816551.1"
                     /translation="MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIP
                     VRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPY
                     GGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDE
                     YSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQG
                     FGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETI
                     SNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILL
                     VPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDM
                     RLAAYIIGIKRTAEAARYRGWA"
     gene            complement(3074..4003)
                     /locus_tag="RFE25_001489"
     CDS             complement(3074..4003)
                     /locus_tag="RFE25_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDU2816552.1"
                     /translation="MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQ
                     WHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMH
                     DETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERY
                     GPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHR
                     QNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHP
                     YTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK"
     gene            complement(4245..5624)
                     /gene="argH"
                     /locus_tag="RFE25_001490"
     CDS             complement(4245..5624)
                     /gene="argH"
                     /locus_tag="RFE25_001490"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDU2816553.1"
                     /translation="MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHAT
                     MLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGG
                     KLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQR
                     AQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLN
                     FGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFST
                     GSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVH
                     TIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKI
                     VLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQL
                     DVAKQLLSQ"
     gene            complement(5614..6819)
                     /locus_tag="RFE25_001491"
     CDS             complement(5614..6819)
                     /locus_tag="RFE25_001491"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDU2816554.1"
                     /translation="MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDI
                     VYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVE
                     IAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKH
                     NIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIIL
                     TFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAE
                     VILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVS
                     GDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAM
                     LHGGYSNEQ"
     gene            7170..8501
                     /locus_tag="RFE25_001492"
     CDS             7170..8501
                     /locus_tag="RFE25_001492"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDU2816555.1"
                     /translation="MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDF
                     LGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNS
                     NEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEER
                     YGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAG
                     INIEAMMIGAAKAREELSSDKLEDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFN
                     EWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDIT
                     IEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVV
                     YFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL"
     gene            8826..9401
                     /locus_tag="RFE25_001493"
     CDS             8826..9401
                     /locus_tag="RFE25_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDU2816556.1"
                     /translation="MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINI
                     QAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLI
                     PLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTH
                     PLRGILMLVVLVVFWIVGKKLEQHFMGSKKE"
     gene            9406..9930
                     /gene="lepB"
                     /locus_tag="RFE25_001494"
     CDS             9406..9930
                     /gene="lepB"
                     /locus_tag="RFE25_001494"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDU2816557.1"
                     /translation="MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGD
                     RVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDAS
                     YAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISL
                     RYYPFSKWTIQFKS"
     gene            9946..10521
                     /gene="lepB"
                     /locus_tag="RFE25_001495"
     CDS             9946..10521
                     /gene="lepB"
                     /locus_tag="RFE25_001495"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDU2816558.1"
                     /translation="MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDG
                     ERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQD
                     EPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGL
                     IDEDQIVGKVSFRFWPFSEFKHNFNPENTKN"
     gene            10681..14154
                     /gene="addB"
                     /locus_tag="RFE25_001496"
     CDS             10681..14154
                     /gene="addB"
                     /locus_tag="RFE25_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDU2816559.1"
                     /translation="MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQST
                     FQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQE
                     QQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDI
                     ALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKG
                     LIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNN
                     QDLKHLEQEFDVLQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIA
                     ILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLR
                     LLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTE
                     DERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERD
                     ELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMI
                     PQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVE
                     LSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLE
                     ITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQ
                     GLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNE
                     RTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLL
                     NSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLT
                     TTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYM
                     DIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLV
                     NADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFI
                     ETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQ
                     NININDEFGGE"
     gene            14158..17811
                     /gene="addA"
                     /locus_tag="RFE25_001497"
     CDS             14158..17811
                     /gene="addA"
                     /locus_tag="RFE25_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDU2816560.1"
                     /translation="MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVER
                     IIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQ
                     AQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAF
                     IELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLT
                     DLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTDH
                     EFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKNDYFSREADDLKADMQ
                     QLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYR
                     QHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIE
                     KYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYG
                     APYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRS
                     ATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPL
                     QDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMF
                     LSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFEN
                     SSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLS
                     KDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVY
                     VALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQ
                     SASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNG
                     NEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFST
                     YERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADA
                     KKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMID
                     LIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVK
                     GYLYFFKFGTLQL"
     gene            17977..18879
                     /locus_tag="RFE25_001498"
     CDS             17977..18879
                     /locus_tag="RFE25_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDU2816561.1"
                     /translation="MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTL
                     LAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNY
                     KDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKI
                     PKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENV
                     NIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMEPPK
                     FLQPGDEVKVTIDNIGTLTTYIAK"
     gene            19208..19597
                     /locus_tag="RFE25_001499"
     CDS             19208..19597
                     /locus_tag="RFE25_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YisL family protein"
                     /protein_id="HDU2816562.1"
                     /translation="MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFM
                     LLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHKMFWI
                     TMALIIITMVLGVILPLGPISKLFGIG"
     gene            complement(19769..21085)
                     /locus_tag="RFE25_001500"
     CDS             complement(19769..21085)
                     /locus_tag="RFE25_001500"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDU2816563.1"
                     /translation="MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCA
                     LPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQF
                     EESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVIGAGYVS
                     LEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIDAINGN
                     EITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIG
                     DIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFA
                     SVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGA
                     DKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK"
     gene            complement(21137..21961)
                     /locus_tag="RFE25_001501"
     CDS             complement(21137..21961)
                     /locus_tag="RFE25_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDU2816564.1"
                     /translation="MQPHLICLDLDGTLLNDNKEISSYTKQVLNELQQRGHQIMIATG
                     RPYRASQMYYHELNLTTPIVNFNGAYVHHPKDKNFKTCHEILDLGIAQNIIQGLQQYQ
                     VSNIIAEVKDYVFINNHDPRLFEGFSMGNPRIQTGNLLVHLKESPTSILIEAEESKIP
                     EIKNMLTHFYADHIEHRRWGAPFPVIEIVKLGINKARGIEQVRQFLNIDRNNIIAFGD
                     EDNDIEMIEYARHGVAMENGLQELKDVANNITFNNNEDGIGRYLNDFFNLNIRYYC"
     gene            22075..22383
                     /locus_tag="RFE25_001502"
     CDS             22075..22383
                     /locus_tag="RFE25_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HDU2816565.1"
                     /translation="MEEALKDSILGALEMVIDPELGIDIVNLGLVYKVNVDDEGVCTV
                     DMTLTSMGCPMGPQIIDQVKTVLAEIPEIQDTEVNIVWSPPWTKDMMSRYAKIALGVS
                     "
     gene            22931..24367
                     /locus_tag="RFE25_001503"
                     /pseudo
     CDS             22931..24367
                     /locus_tag="RFE25_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499464.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
     gene            25080..27689
                     /gene="clpB"
                     /locus_tag="RFE25_001504"
     CDS             25080..27689
                     /gene="clpB"
                     /locus_tag="RFE25_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDU2816566.1"
                     /translation="MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESES
                     LYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKE
                     YEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEAL
                     AKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGL
                     AQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFI
                     DEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQK
                     VAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDL
                     VDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANE
                     KEKQAALQSRVESEKEKIANLQEKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQL
                     EKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHL
                     SDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAA
                     SLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDE
                     VEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEIT
                     ESTEKAVMTNLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRIS
                     IEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNS
                     DNNLTFNVEKIHE"
     gene            complement(27748..28617)
                     /locus_tag="RFE25_001505"
     CDS             complement(27748..28617)
                     /locus_tag="RFE25_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDU2816567.1"
                     /translation="MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLN
                     VKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIA
                     TFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVC
                     EGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYGKAQFLSIND
                     VHTSIKLIEMNQGISFLPIYITTDSDYNISVINTKILQAPISFTYIYSKKESPEILVF
                     IKSFKKYIANEQL"
     gene            28727..29871
                     /locus_tag="RFE25_001506"
                     /pseudo
     CDS             28727..29871
                     /locus_tag="RFE25_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499467.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            29855..>30442
                     /locus_tag="RFE25_001507"
     CDS             29855..>30442
                     /locus_tag="RFE25_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HDU2816568.1"
                     /translation="MEILNDSVKSFEKLYLQLQDGFPVIVPTDTNYNLCSLPNNDLCI
                     DKIFEYKKRSKDKPLSLFIDKPEDWKLYGDNQNTEIVDKLVEIFWPGPLNIILKNKTS
                     YNYMLNNSDSIAIGCVQNKTMRRFISYINSPIAITSANISGTADDILITENEAIKHMG
                     ENVRYMLRSQNKTNYKTSSTIIKVTDNKIELLREGD"
BASE COUNT        10714 a         4348 c         5430 g         9950 t
ORIGIN      
        1 aattcttttg cttgtaatca tttaagtaat tatgtcatta taaatgtaag agttttcaaa
       61 atagacaaat ttaatgaaac ttagtgatta tttcatcttt tttggtggaa aagtatctgc
      121 tttgaaaact aatgtaatta tttggataat gtttcatgta taatagttat aaatgatgaa
      181 aaggggagat atgatgacta aatctgaaaa aattattgag ttaacaaatc attacggagc
      241 acataattat ttaccattgc caattgtcat ttcagaagct gaaggggtat gggttaaaga
      301 tcctgaaggc aataaatata tggatatgtt atctgcatat tccgctgtta accaaggtca
      361 tagacatccg aaaattattc aagcattaaa agatcaagct gataaagtga ctctagtttc
      421 acgtgctttt catagtgata acttaggtga atggtacgaa aaaatttgta aactggcagg
      481 taaagataaa gctttaccaa tgaatacagg tgctgaagca gtagaaacag ctttgaaagc
      541 agcacgacgc tgggcatacg atgttaaagg aattgagcca aataaagcag aaatcattgc
      601 atttaatggt aacttccatg gtcgaacaat ggcgccagtt tcattatctt cagaagcaga
      661 ataccaacgt ggttatggtc cgttattaga tggatttaga aaagttgatt ttggagatgt
      721 agatgcattg aaagctgcaa ttaatgaaaa tactgcagca gttttagtag aaccaattca
      781 aggtgaagcg ggtataaata taccgccaga aggatatttg aaagcaatta gagaattatg
      841 tgatgaacat aatgtcttat ttattgctga cgaaatccaa gcaggattag gtcgttcggg
      901 taaattattt gctacggatt gggataatgt aaaacctgat gtctatattt taggtaaagc
      961 actaggtggt ggtgtcttcc caatttctgt tgtattagca gataaagaag tattagatgt
     1021 ctttacacct ggctcacatg gttcaacatt tggtggtaat ccacttgctt gtgctgcatc
     1081 aattgctgca ttagatgtta tcgttgatga ggatttacca gggcgctctt tagaattagg
     1141 agattatttt aaagaacaat taaagcaaat tgatcatcca tcaattaaag aagtccgtgg
     1201 acgtggtttg tttataggtg tggaacttaa tgaaagtgct agaccatatt gtgaagcttt
     1261 gaaagaagaa ggcttattat gtaaagaaac gcatgatact gtcattcgtt ttgcaccacc
     1321 attaattatt actaaagaag aattggacct tgcacttgaa aaaataagac atgtatttca
     1381 ataatgtcaa aaagttgtaa caatcagttt gtaagggctt taaaaaggaa tacgttatgt
     1441 tacaatatgt ttgaaagcga aatcattagg taaagaagag gcgaaaagga tcatgactga
     1501 gaacaataat ttagtaactt ctactcaagg aattattaaa gaagcattgc ataaattggg
     1561 atttgacgaa ggaatgtacg atttaattaa agaaccttta agaatgttac aagtgcgtat
     1621 ccctgtacga atggatgatg gcacagttaa aacattcaca ggttaccgtg cgcaacataa
     1681 tgatgctgtt ggaccaacaa aagggggcgt gcgtttccac ccagatgttg atgaagaaga
     1741 agtaaaagca ttatcaatgt ggatgacttt gaaatgtggc attgtaaact taccatacgg
     1801 tggtggtaag ggtggtatcg tttgtgatcc acgtcaaatg agcattcatg aagttgaacg
     1861 tttatcacgc ggatatgtaa gagcaatttc acaattcgta ggtccgaaca aagatattcc
     1921 agcaccagat gtatttacaa actcacaaat tatggcttgg atgatggatg aatatagtgc
     1981 attagataaa tttaattcac caggtttcat cacaggtaaa ccaattgtat tgggtggttc
     2041 tcatggacgc gacagatcaa ctgcactagg tgtagttatt gcaattgaac aagctgcaaa
     2101 acgtcgtaat atgcaaattg aaggtgccaa ggttgttatt caaggtttcg gtaatgccgg
     2161 aagtttctta gctaaattct tatatgattt aggtgcaaaa attgtaggta tctctgatgc
     2221 ttacggtgca ttacacgatc caaatggctt agatatagat tatttattag accgtcgtga
     2281 tagttttggt acggtaacaa atttatttga agaaacaatc tcaaataaag aattgtttga
     2341 attagattgt gacattttag taccagcggc tatttcaaac caaattacag aagacaatgc
     2401 acatgatatt aaagctagta tcgttgttga agctgctaat ggacctacaa caccagaagc
     2461 aacacgtatt ttaactgaac gtggtatatt attagttcca gacgtattag caagtgctgg
     2521 tggtgtaacg gtttcttact tcgaatgggt acaaaataat caaggttatt attggtctga
     2581 agaagaagta aatgaaaagc tacgtgaaaa attagaagcg gcatttgaca cgatttacga
     2641 attgtctcaa aatcgaaaaa tagatatgag acttgcagca tatatcatag gtattaaacg
     2701 tacagcagaa gcagctagat atcgtggttg ggcataatta attatcatat gtgatttaac
     2761 gagcttggga cagaaaacaa agccctaagc tcgttaattt tattttagca gcagttgact
     2821 gtaaaacaat gcccgtgtaa cacgctcttt tcaaaaatag tcggggcccc aacacagagg
     2881 ctggtggaaa gtcagcttac aatagtgtgc aagttggctg gcccccaaca ctgagaattt
     2941 ctaattaaac gctcaactat atatagttga tcaaaaagac agcagtagga taatttcaat
     3001 ttggaaatat cttactgctg ttttttatag taatagctat atttttgtat ttatgttttc
     3061 tagtttaaca atactactta atgacttctt tatatttatc agcgaaattt gtaaagacac
     3121 catcaacgcc atatttattt aatcgtaaca tatcagcttt ttcattcact gtataaggat
     3181 gtactataaa tcctaagtct tttaaatgat gggtattttg ttcagttaaa tctgtataat
     3241 caggacctaa tccaatcgca taagagcgta tctcttttaa gcgttggtcg ttaaattgtt
     3301 gtagttcacc tttatcaact aattttacta atggcacatg cttattttga cgatgaattt
     3361 tctttaaact ttcgtcagaa aatgattgaa tcattacatg tccatttttt aatttattgt
     3421 tatttaaaag gtgatgcttt ttcaatgaag ctaataattg ttcttccatt cctgggtata
     3481 catcaggtga ctttgtttca atataatagt ttgcattcgg gccataacgt tctaaaattt
     3541 catctaaagt gggtacttta gcatttttat aacttgctct tgcgtatttt ggatattttt
     3601 tattaaacca acttcctgca tctaactgtt ttaattcatc aagggtataa tcctcaactt
     3661 taccgtgtcc atttgttgta cggttaacag tttcatcatg catagcaact aaatgtccat
     3721 ctttggtacg ttgtaaatca atttcgatat aagatgcttt taactcatta tgactcttat
     3781 catatgcttg aaacgtatgc tctggtgcat agccacttgc gccacgatgt gcgatagtag
     3841 tgaatcgctc attcgttaaa tttgtatgcc attgaatagc ctgaggttta tttgcaattt
     3901 gatttgtttg ttcagcgcca gcagtaggta ctgataaaaa tcccatagta aaaacagcag
     3961 aagcagccat aaatttagtg aagcttttcg aagagttagt catagtcttt atcctttcat
     4021 ctctttattt gtagtctaac aattttaaaa tactacaaaa acctgcttgt gaaaacgctt
     4081 tacacatttc ttttacaatt tataacattt ctgtaatata aatttaaaag aattatcaaa
     4141 cattttagga atcttaaaaa tgtgatgttc aacaagacga agagagcatt aaaataccca
     4201 caatgtaatt ttaatagaca ttgtgggtag gtagattaac gtatttattg tgatagtaat
     4261 tgtttagcaa catcaagttg ttgtttgacc gatgattgcc ccgttgaccc gtaactttga
     4321 cgtcgtttca agcaattttc aggctgcaaa taatcgtaaa tatcggcatc gatactagaa
     4381 tgatgttgtt gatatgttgc taaaggaaca tctaataaat aatgaccttg ttgtatacat
     4441 tctaagacga tttttcctac aatttcatgt gcagttctaa atggaatatt tttagttact
     4501 aaataatctg ctagttccgt tgcatttgaa aaatcttctt taacagtttg attgagtcgt
     4561 tctttattaa ttgtcatcgt ttgaatcata ccttcgaaaa tacgtaaaga acctttaatt
     4621 gtatggacag catcgaataa accttcttta tcttcctgca tatctttgtt atatgctaga
     4681 ggtaatcctt ttaaagtcat aagcatgctc attaaatgac cagtcgttcg accaacttta
     4741 cctctaatta attctgccat atcaggattt ttcttttgtg gcataataga tgagccagtt
     4801 gaaaatgcat ctgataatgt aatgaattta gcttcgtctg tggaccagaa aataatttcc
     4861 tctgcaaagc gtgataagtg aaccatcgtt aaagaaatat tatgcaatgt ttcaataata
     4921 tagtctctgt cactaacagc atctaggcta ttctcataga gactgccaaa gttcaacaat
     4981 gctgttgtct cgtgtctatc gatagggtat gtggtaccac ttaaggctgc tgcacctaaa
     5041 ggattaatat cgattcgttt taaactatct tcaaatcgtt gttggtctcg ttgtaacatc
     5101 caaaaataag tcataatatg atgtgcaaat gaaattggct gtgcacgctg taaatgagta
     5161 taaccaggca taattgtatc aacattattg gaagcgatgt ctacaattac actttgtaac
     5221 gacttaatta atgcgatgat atcttgcact tgtttcttag tgtacaagtg catatctgtt
     5281 gcaacttgat cgtttctact gcgtccagta tgcaacttac caccagcatc accaatacgt
     5341 ttaattaatt catgttcaat atttaaatga atatcttcta atgatgcact aaattgaatt
     5401 tgatcttgat gataatcatg ttgaatagat tttagtcctt gtataatttg ttcgctgtct
     5461 tgttgactaa taatgccttg attcgcaagc atagttgcat gcgcaatgct gccttcgata
     5521 tcttgatcta tgagcgtttg gtcaaaagta atggatgcgt taaagtcgtc aacccactct
     5581 tcaggttgta cttcaaatct accgccccaa gctttattgc tcattgctat agcctccatg
     5641 caacatcgca tttacttgag taggtaaacc atagatatcg ataaagccaa cagcagcgtc
     5701 ttgattaaat gcatcttctt ttgtataagt tgctaatttt tcatcatata atgtgtaagg
     5761 tgattttcta ccattcacga tggcattacc tttgaataat ttaattctga catcaccact
     5821 tacgtattgc tgagtactat caataaataa tttcaagcta tcagttaaag gtgagaacca
     5881 aagtccattg tatagttgtt cagcaaattg cttctcaatg attggtttaa agtgtgcgac
     5941 atctttagtt aacgtaatcg tttctaatgc tttatgcgct tttaaaataa cttctgcagc
     6001 aggtgcctca taaatttctc ttgatttgat acctacaagt ctattttcta catggtcaat
     6061 tcttccgata ccatgcttac cagctaatgc attcaacgtt aaaattaaat cgtctaattc
     6121 atatgttttg ccatcaattt gaactgggat gcctttatca aacgttaaaa tgatttcatc
     6181 agcagtatct ggtgtttctt ctaaagcatt tgttagatcg aacgcatcct ctggtggcgc
     6241 agcataagga tcttctaaaa taccacattc attcgctctg ccccatagat tttgatcgat
     6301 agaataaggt gaatcatggt tgattgatac agggatatta tgtttaattg cataatcgat
     6361 ttcttcttca cgactccatg cccactcacg tacaggtgcg aatgctttca atgatgggtt
     6421 taatgcttta atggcaactt cgaaacgtac ttggtcattc cctttaccag tacaaccatg
     6481 tgcaatgcct actgaatttg ttttctcagc aatctctact aattttttag cgattaatgg
     6541 tcttgataaa gctgaaacta atggatatgc attttcatac attaaatttc ctttgattgc
     6601 ataacttaca tactcatcac taaattcttt tgttgcatca ataatatgac attcaactgc
     6661 tcccatatct aaagcttttt tataaacgat gtctaaatct ttaccttcac caacatctag
     6721 gcaacaagct acaacgtcgt atcctttgtc gataagccat tgaacggcca cacttgtatc
     6781 tagtcctcct gaatatgcta aaacaatttt ctctttcata aaattcacct cattgtagtt
     6841 atctgaatat ttcgtatgaa cacatgatag caaactttta atgaaaataa aaccattatt
     6901 ttacatattt attcataaaa tgcgatagag atagttagag ttgtaagtat aaatgcttat
     6961 ttatcaatgt ttaaaagtat tttaaaaaac atgcaaattg tataaaaaat gtttgagtgt
     7021 ttgacgccag tttgaaatgt ttgttgaaaa ataggtgtga aacgtcacat aaatatcaat
     7081 tttattgatt aagtacaaac ttgtgaattg aatcgcaaac gtaaacttag taaaattaag
     7141 atattaaatg aaacaggagg cttttataga tgactcatat tcaattagat tttagtaaaa
     7201 cgttagaatt tttcggtgaa cacgaattaa aacaacaaca agaaattgtt aaatcaattc
     7261 acaaaacaat tcatgaaggt actggtgcag gtagtgactt cttaggctgg gttgatttac
     7321 cagttgatta cgacaaagaa gaattttcaa gaattgttga agcatcaaaa cgcattaaag
     7381 aaaattctga tgttttagta gtcatcggta ttggtggttc ttacttaggt gcacgtgcag
     7441 caatcgaaat gttaacgtca tcatttagaa acagcaatga ataccctgaa attgtatttg
     7501 ttggtaatca cttatcatca acatatacga aagagttagt tgattattta gcagacaaag
     7561 atttctctgt aaacgttatt tctaaatctg gtacaactac agaaccagca gttgcattta
     7621 gattgttcaa acaattagtt gaagaaagat acggtaaaga agaagcacaa aaacgtatat
     7681 ttgcaacaac ggataaagaa aaaggtgctt taaaacagtt ggctacaaac gaaggttatg
     7741 aaacgtttat cgtacctgat gatgtaggtg gaagatattc tgttttaaca gcagtaggat
     7801 tattaccaat tgcaacagct ggaattaaca tcgaagctat gatgattggt gctgcaaaag
     7861 cacgtgaaga attatcttca gataaattag aagacaacat tgcataccaa tatgcgacaa
     7921 ttcgaaacat tttatatgca aaaggttata caacagaaat gttgattaac tatgaaccat
     7981 ctatgcaata ctttaatgaa tggtggaaac aattatttgg tgaatcagaa ggtaaagact
     8041 tcaaaggtat ctatccttca agtgccaact acacaactga tttacattct ttaggtcaat
     8101 atgtacaaga aggccgtcgt ttcttattcg aaacagtggt aaaagtaaat catcctaaat
     8161 atgatattac tattgaaaaa gatagtgatg atctagacgg attaaattat ttggctggta
     8221 aaacaatcga cgaagttaac acaaaagcat tcgaaggtac attattagcg catactgatg
     8281 gtggtgttcc taacatggta gtgaacattc cacaattaga tgaagaaact ttcggttatg
     8341 tcgtatactt cttcgaactt gcttgtgcaa tgagtggata ccaattaggt gtaaatccat
     8401 ttaaccaacc tggtgtagaa gcatataaac aaaacatgtt cgcattatta ggtaaacctg
     8461 gttttgaaga cttgaaaaaa gaattagaag agcgtttata aaatacatta cttcaatgat
     8521 tagtgaagtt tgaaaagata gaactagacg ttaactattt aaagcatatt ttcgaggttg
     8581 tcattacaaa tgtaaaaatg taatgacaac ctcgttttta tttatatgca agaactaggt
     8641 tactagctaa tgtgacaaga tgttaagaga aaattaaaga aaaaataaca tctgtcatac
     8701 aataatattg ttatactact agagactgat ttattagcat gattacatgt taatgtttct
     8761 ttacttagta attaacttta taatgtaaga ataattatct tcaaccaaag aaagggattg
     8821 atgatttgtc gtttcatcaa gtagaagaat ggtttgagat atttcgacag tttggttatt
     8881 tacctggatt tatattgtta tatattagag cgataattcc agtatttcct ttagcactct
     8941 atattttaat taacattcaa gcttatggac ctattttagg tatattgatt agttggcttg
     9001 gattaatttc tggaacattt acagtctatt tgatctgtaa acgattggtg aacactgaga
     9061 ggatgcagcg aattaaacaa cgtactgctg ttcaacgctt gattagtttt attgatcgcc
     9121 aaggattaat cccattgttt attttacttt gttttccttt tacgccaaat acattaataa
     9181 attttgtagc gagtctatct catattagac ctaaatatta tttcattgtt ttggcatcat
     9241 caaagttagt ttcaacaatt attttaggtt atttaggtaa ggaaattact acaattttaa
     9301 cgcatccttt aagagggata ttaatgttag ttgtgttggt tgtattttgg attgttggaa
     9361 aaaagttaga acagcatttt atgggatcga aaaaggagtg acatcgtgaa aaaagttgta
     9421 aaatatttga tttcattgat acttgctatt atcattgtac tgttcgtaca aacttttgta
     9481 atagttggtc atgtcattcc gaataatgat atgtcaccaa cccttaacaa aggggatcgt
     9541 gttattgtaa ataaaattaa agttacattt aatcaattga ataatggtga tatcattaca
     9601 tataggcgtg gtaacgagat atatactagt cgaattattg ccaaacctgg tcaatcaatg
     9661 gcgtttcgtc agggacaatt ataccgtgat gaccgaccgg ttgacgcatc ttatgccaag
     9721 aacagaaaaa ttaaagattt tagtttgcgc aattttaaag aattagatgg agatattata
     9781 ccgcctaaca attttgttgt gctaaatgat catgataaca atcagcatga ttctagacaa
     9841 tttggtttaa ttgataaaaa ggatattatt ggtaatataa gtttgagata ttatcctttt
     9901 tcaaaatgga cgattcagtt caaatcttaa aaagaggtgt caaaattgaa aaaagaatta
     9961 ttggaatgga ttatttcaat tgcagtcgct tttgtcattt tatttatagt aggtaaattt
    10021 attgttacac catatacaat taaaggtgaa tcaatggatc caactttgaa agatggcgag
    10081 cgagtagctg taaacattat tggatataaa acaggtggtt tggaaaaagg taatgtagtt
    10141 gtcttccatg caaacaaaaa tgatgactat gttaaacgtg tcatcggtgt tcctggtgat
    10201 aaagtagaat ataaaaatga tacattatat gtcaatggta aaaaacaaga tgaaccatat
    10261 ttaaactata atttaaaaca taaacaaggt gattacatta ctgggacttt ccaagttaaa
    10321 gatttaccga atgcgaatcc taaatcaaat gtcattccaa aaggtaaata tttagttctt
    10381 ggagataatc gtgaagtaag taaagatagc cgtgcgtttg gcctcattga tgaagaccaa
    10441 attgttggta aagtttcatt tagattctgg ccatttagtg aatttaaaca taatttcaat
    10501 cctgaaaata ctaaaaatta atatgaaaca aatacaacat cgtttgtcgg ttttaatact
    10561 gataaacgat gttttatttt gttagtacca caataaaatc taagttcgaa atgaacttat
    10621 aataaatcaa tcacaatcac tttgtgttaa aatatgtgtc aaaggaagtg agggtttgtc
    10681 atgacattac atgcttattt aggtagagcg ggaacaggta agtctacgaa aatgttgacc
    10741 gaaataaaac aaaaaatgaa agcagatccg cttggagatc caatcatttt aattgcgcca
    10801 actcaaagta catttcaatt agaacaagcc tttgtcaatg atccggaatt aaatggtagt
    10861 ttaagaacag aagtgttgca ttttgaacga ttaagtcatc gtattttcca agaagttggt
    10921 agttatagcg aacaaaagtt atctaaagct gcaacggaaa tgatgattta taacattgtt
    10981 caagaacaac aaaagtattt aaaactttat caatcacaag caaaatatta tgggtttagt
    11041 gaaaaattaa cagaacaaat tcaagatttt aaaaaatatg cagtaacgcc tgaacattta
    11101 gaacacttta ttgctgataa aaatatgcaa actcgaacta aaaataagtt agaggatatt
    11161 gctttaatat accgtgagtt cgaacaacgc attcaaaacg agtttattac tggtgaggat
    11221 tcattacaat attttattga ttgtatgccg aaatcagagt ggctaaaacg tgctgatata
    11281 tatattgatg gttttcacaa cttttcaacg attgagtatt taataatcaa aggattaatt
    11341 aaatatgcga agagtgtcac aattatattg acgacagatg gtaaccacga tcaatttagt
    11401 ttatttagaa aaccatcgga agtgttacga catattgaag aaatagcaaa tgaactcaat
    11461 atttctattg aacgtcaata tttcaaccaa ttatatcgct tcaataatca agatttaaag
    11521 catcttgaac aagaatttga tgtacttcaa atcaatcgag tggcatgtca aggtcatatc
    11581 aatattttag aatctgcgac tatgagagag gaaataaatg aaattgcgcg acgtatcatc
    11641 gttgatattc gtgataagca attacgatat caagatattg caattttata tcgtgacgag
    11701 tcttatgctt atttatttga ttccatatta ccgctttata atattcctta taacattgat
    11761 acaaagcgtt cgatgacaca tcatccggtc atggaaatga ttcgttcatt gattgaagtt
    11821 attcaatcta attggcaagt gaatccaatg ctacgcttat tgaagactga tgtgttaacg
    11881 gcatcatatc taaaaagtgc atacttagtt gatttacttg aaaattttgt acttgaacgt
    11941 ggtatatacg gtaaacgttg gttagatgat gagctattta atgtcgaaca ttttagcaaa
    12001 atggggcgta aagcgcataa actgaccgaa gatgaacgta acacatttga acaagtcgtt
    12061 aagttaaaga aagatgtcat tgataaaatt ttacattttg aaaagcaaat gtcacaagcg
    12121 gaaactgtaa aagactttgc aactgctttt tatgaaagta tggaatattt cgaactgcca
    12181 aatcaattga tgacagagcg agatgaactt gatttaaatg gtaatcatga aaaggcggag
    12241 gaaattgatc aaatatggaa tggcttaatt caaatccttg acgacttagt tctagtattt
    12301 ggagatgaac caatgtcgat ggaacgtttc ttagaagtat ttgatattgg tttagaacaa
    12361 ttagaatttg tcatgattcc acaaacatta gatcaagtta gtattggtac gatggatttg
    12421 gctaaagtcg acaataagca acatgtttac ttagttggaa tgaacgacgg caccatgcca
    12481 caaccagtaa ctgcatcaag tttaattact gatgaagaaa agaaatattt tgaacaacaa
    12541 gcaaatgtag agttgagtcc tacatcagat attttacaga tggatgaagc atttgtttgc
    12601 tatgttgcta tgactagagc taagggagat gttacatttt cttacagtct aatgggatca
    12661 agtggtgatg ataaggagat cagcccattt ttaaatcaaa ttcaatcatt gttcaaccaa
    12721 ttggaaatta ctaacattcc tcaataccat gaagttaacc cattgtcact aatgcaacat
    12781 gctaagcaaa ccaaaattac attatttgaa gcattgcgtg cttggttaga tgatgaaatt
    12841 gtggctgata gttggttaga tgcttatcaa gtaattagag atagcgatca tttaaatcaa
    12901 ggtttagatt atttaatgtc agcattaacg tttgacaatg aaactgtaaa attaggtgaa
    12961 acgttgtcta aagatttata tggtaaggaa atcaatgcca gtgtatctcg ttttgaaggt
    13021 tatcaacaat gcccatttaa acactatgct tcacatggtc tgaaactaaa tgaacgaacg
    13081 aaatatgaac ttcaaaactt tgatttaggt gatattttcc attccgtttt aaaatatata
    13141 tctgaacgta ttaatggcga ttttaaacaa ttagacctga aaaaaataag acaattaacg
    13201 aatgaagcat tggaagaaat tttacctaaa gttcagttta atttattaaa ttcttcagct
    13261 tactatcgtt atttatcaag acgcattggc gctattgtag aaacaacact aagcgcatta
    13321 aaatatcaag gcacgtattc aaagtttatg ccaaaacatt ttgagacaag ttttagaagg
    13381 aaaccaagaa caaatgacga attaattgca caaacattaa cgacaactca aggtattcca
    13441 attaatatta gagggcaaat tgaccgtatc gatacgtata caaagaatga tacaagtttt
    13501 gttaatatca ttgactataa atcctctgaa ggtagtgcga cacttgattt aacgaaagta
    13561 tattatggta tgcaaatgca aatgatgaca tacatggata tcgttttaca aaataaacaa
    13621 cgccttggat taacagatat tgtgaaacca ggtggattat tatacttcca tgtacatgaa
    13681 cctagaatta aatttaaatc atggtctgat attgatgaag ataaactaga acaagattta
    13741 attaaaaagt ttaagctgag tggtttagtg aatgcagacc aaactgttat tgatgcattg
    13801 gatattcgtt tagaacctaa attcacttca gatattgtac cagttggttt gaataaagat
    13861 ggctctttga gtaaacgagg cagccaagtg gcagatgaag caacaattta taaattcatt
    13921 cagcataaca aagagaattt tatagaaaca gcttcaaata ttatggatgg acatactgaa
    13981 gttgcaccat taaagtacaa acaaaaattg ccatgtgctt tttgtagtta tcaatcggta
    14041 tgtcatgtag atggcatgat tgatagtaag cgatatcgaa ctgtagatga aacaataaat
    14101 ccaattgaag caattcaaaa tattaacatt aatgatgaat ttgggggtga gtaatagatg
    14161 acaattccag agaaaccaca aggcgtgatt tggactgacg cgcaatggca aagtatttac
    14221 gcaactggac aagatgtact tgttgcagcc gcggcaggtt caggtaaaac agctgtacta
    14281 gttgagcgta ttatccaaaa gattttacgt gatggcattg atgtcgatcg acttttagtc
    14341 gtaacgttta caaacttaag cgcacgtgaa atgaagcatc gtgtagacca acgtattcaa
    14401 gaggcatcga ttgctgatcc tgcaaatgca cacttgaaaa accaacgcat caaaattcat
    14461 caagcacaaa tatctacact tcatagtttt tgcttgaaat taattcaaca gcattatgat
    14521 gtattaaata ttgacccgaa ctttagaaca agcagtgaag ctgaaaatat tttattatta
    14581 gaacaaacga tagatgaggt catagaacaa cattacgata tccttgatcc tgcttttatt
    14641 gaattaacag aacaattgtc ttcagataga agtgatgatc agtttcgaat gattattaaa
    14701 caattgtatt tctttagcgt tgcaaatcca aatcctacaa attggttgga tcaattggtg
    14761 acaccatacg aagaagaagc acaacaagcg caacttattc aactactaac agacttatct
    14821 aaagtattta tcacagctgc ctatgatgct ttaaataagg cgtatgattt gtttagtatg
    14881 atggatggcg tcgataaaca tttagctgtt atagaagatg aacgacgttt aatggggcgt
    14941 gttttagaag gtggttttat tgatatacct tatttaactg atcacgaatt tggcgcgcgt
    15001 ttgcctaatg taacagcgaa aattaaagaa gcaaatgaaa tgatggtcga tgccttagaa
    15061 gatgctaaac ttcagtataa aaaatataaa tcattaattg ataaagtgaa aaatgattac
    15121 ttttcaagag aagctgatga tttgaaagct gatatgcaac aattggcgcc acgagtaaag
    15181 taccttgcgc gtattgtgaa agatgttatg tcagaattca atcgaaaaaa gcgtagcaaa
    15241 aatattctgg atttttctga ttatgaacat tttgcattac aaattttaac taatgaggat
    15301 ggttcgcctt cagaaattgc cgaatcatac cgtcaacact ttcaagaaat attggtcgat
    15361 gagtatcaag atacgaaccg ggttcaagag aaaatactat cttgcatcaa aacgggtgat
    15421 gaacataatg gtaatttatt tatggttgga gatgttaagc aatccattta taaatttaga
    15481 caagctgatc caagtttatt tattgaaaag tatcaacgct ttactataga tggagatggc
    15541 actggacgtc gaattgattt gtcgcaaaac ttccgttctc gaaaagaagt actgtcaacg
    15601 actaactata tattcaaaca tatgatggat gaacaagtcg gtgaagtaaa atatgatgaa
    15661 gcggcacagt tgtattatgg tgcaccatat gatgaatcgg accatccagt aaacttaaaa
    15721 gtgcttgttg aagcggatca agaacatagt gatttaactg gtagtgaaca agaagcgcat
    15781 tttatagtag aacaagttaa agatatctta gaacatcaaa aagtttatga tatgaaaaca
    15841 ggaagctata gaagtgcgac atacaaagat atcgttattc tagaacgcag ctttggacaa
    15901 gctcgcaatt tacaacaagc ctttaaaaat gaagatattc cattccatgt gaatagtcgt
    15961 gaaggttact ttgaacaaac agaagtccgc ttagtattat catttttaag agcgatagat
    16021 aatccattac aagatattta tttagttggg ttaatgcgct ccgttatata tcagttcaaa
    16081 gaagacgaat tagctcaaat tagaatattg agtccaaatg atgactactt ctatcaatcg
    16141 attgtaaatt acattaatga cgaagcagca gatgctattt tagttgataa attaaaaatg
    16201 tttttatcag atattcaaag ttaccaacaa tatagtaaag atcatccggt gtatcagtta
    16261 attgataaat tttataatga tcattatgtt attcaatact ttagtggact tattggtgga
    16321 cgtggacgac gtgcaaacct ttatggttta tttaataaag ctatcgagtt tgagaattca
    16381 agttttagag gtttatatca atttattcgt tttatcgatg aattgattga aagaggcaaa
    16441 gattttggtg aggaaaatgt agttggtcca aacgataatg ttgttagaat gatgacaatt
    16501 catagtagta aaggtctaga gtttccattt gtcatttatt ctggattgtc aaaagatttt
    16561 aataaacgtg atttgaaaca accagttatt ttaaatcagc aatttggtct cggaatggat
    16621 tattttgatg tggataaaga aatggcattt ccatctttag cttcggttgc atataaagct
    16681 gttgccgaaa aagaacttgt gtcagaagaa atgcgattag tctatgtagc attaacaaga
    16741 gcgaaagaac aactttattt aattggtaga gtgaaaaatg ataaatcgtt actagaacta
    16801 gagcaattgt ctatttctgg tgagcacatt gctgtcaatg aacgattaac ttcaccaaat
    16861 ccgttccatc ttatttatag tattttatct aaacatcaat ctgcgtcaat tccagatgat
    16921 ttaaaatttg aaaaagatat agcacaagtt gaagatagta gtcgtccgaa tgtaaatatt
    16981 tcaattatat actttgaaga tgtgtctaca gaaaccattt tagataataa tgaatatcgt
    17041 tcggttaatc aattagaaac tatgcaaaat ggtaatgagg atgttaaagc acaaattaaa
    17101 caccaacttg attatcaata tccatatgta aatgatacta aaaagccatc aaaacaatct
    17161 gtttctgaat tgaaaaggca atatgaaaca gaagaaagtg gcacaagtta cgaacgagta
    17221 agacaatatc gtatcggttt ttcaacgtat gaacgaccta aatttctaag tgaacaaggt
    17281 aaacgaaaag cgaatgaaat tggtacgtta atgcatacag tgatgcaaca tttaccattc
    17341 aaaaaagaac gcatatctga agttgagtta catcagtata tcgatggatt aatcgataaa
    17401 catattatcg aagcagatgc gaaaaaagat atccgtatgg atgaaataat gacatttatc
    17461 aatagtgagt tatattcgat tattgctgaa gcagagcaag tttatcgtga attaccgttt
    17521 gtagttaacc aagcattagt tgaccaattg ccacaaggag acgaagacgt ctcaattatt
    17581 caaggtatga ttgacttaat ctttgttaaa gatggtgtgc attattttgt agactataaa
    17641 accgatgcat ttaatcgtcg ccgtgggatg acagatgaag aaattggtac acaattaaaa
    17701 aataaatata agatacagat gaaatattat caaaatacgc ttcaaacgat acttaataaa
    17761 gaagttaaag gttatttata cttcttcaaa tttggtacat tgcaactgta gtattttgat
    17821 tttcaaaaga ataaaaaata atttcgatta agtgcaaagt ccttgtagca gaatgaacac
    17881 aactcatttt caaaattgtc ttacttattt atttgttatt tgataacgaa aaaagttata
    17941 atgtgaatta agataaagat gaggagttga gaatgaatga aattcttatc attcaagtat
    18001 aatgacaaaa cttcatatgg cgttaaagta aaacgcgaag atgctgtatg ggatttaaca
    18061 caagtatttg ctgactttgc agaaggagat ttccatccta aaacattgtt agctggttta
    18121 caacaaaatc atactttaga ttttcaagaa caagtacgta aagcagttgt agcagcagaa
    18181 gatagcggca aagctgaaga ctataaaatt tcatttaatg acattgaatt cttaccacca
    18241 gtaacacctc cgaataatgt gattgctttt ggtagaaatt acaaagatca tgcgaacgaa
    18301 ttaaatcatg aagtagaaaa attatatgta tttacaaaag cagcgtcatc tttaacagga
    18361 gataatgcaa caattccaaa tcataaagat attactgatc aattagatta tgaaggtgaa
    18421 ttaggtattg ttattggtaa gtctggtgaa aagattccaa aagcattagc tttagattat
    18481 gtttacggct atacaattat taacgatatc actgatcgca aagcacaaag tgaacaagat
    18541 caagcatttt tatcaaaaag tttaactggc ggttgcccaa tgggtcctta tatcgttact
    18601 aaagacgaac taccattacc tgaaaatgta aatattgtta caaaagttaa caatgaaatt
    18661 agacaagatg gtaacactgg cgaaatgatt cttaaaattg atgaattaat agaagaaatt
    18721 tcaaaatatg ttgcactaca tccgggagat attattgcaa ctggtacacc agcaggcgtt
    18781 ggtgcaggta tggaaccacc taaattttta caaccaggtg atgaagttaa agtgactatt
    18841 gataatattg gaacgctgac aacttatatc gctaaataat tatcatttaa aaagctaacc
    18901 agtctttata tagattggtt agttttttct tgcttttcta aaaaggtgtt aaagataaat
    18961 tatttataat gttaccattt tgagatgaaa gtgaaatatt gatattaaga agtagttgat
    19021 tattttacag cagattcaca atattctaat aaggaataaa atgtcatgtt cttcctctca
    19081 aatatagaag tgtggtagaa tatatattcg tgtataatca aatcatgatt aaattacaag
    19141 caagtgggta ttaatcccaa gaagctttaa tttaataata taaataatta aagtgggggg
    19201 aatcagtatg ttacatttac atatattaag ttgggtatta gcgattattt tatttatcgc
    19261 tacatactta aacatttcaa aaaatcaagg cggatcacca tttttcaaac cgttgcacat
    19321 gattttacgc ttatttatgc tgttgacgtt aatttcagga ttttggatat taattcagtc
    19381 atttatgaat ggcggggcaa atcatatgtt gcttacattg aaaatgctgt gtggtgttgc
    19441 agtagttgga ttgatggaag tgtcgattgc taaaagaaag agacatgaac aaagtcacaa
    19501 aatgttttgg ataacaatgg cattaattat catcacaatg gtattaggtg tcattctacc
    19561 gttagggcct atatcaaaat tattcggtat tggctaattg ataagacata tagtatatga
    19621 cataaggcat ggacaattat tagtccaaga ccttatgtct tttttgattc taaaaatgtt
    19681 taaacataaa aaaaggactg gatagtagta ccagtccaac ataattctaa cctagacaat
    19741 taagattaga ttgaatcgca tgattcattt atttagcttt gtaaccaatc atattgatta
    19801 aatctttagg gtggctatat ggtggtgcat aagccacttc aaactcagtt aactcatcta
    19861 cagttagctg gttcatcatt gccatcgata gtacatcaat acgtttatct gcaccttctt
    19921 ttcctactgc agctgctctt aaaatctgac ggtttgaagt gtcataatat acccttaagt
    19981 gtaaagggga atttcctggg taataattcg cgtgtgcacc ttgagtgact tccaccattt
    20041 tatagtcaaa ttgctttagt tcatttggtt taacgccgac actcgcaaat gtataatcaa
    20101 agaacttcac aatattgttg cctaagaagc ctttgaattc aatagtgtca tttccagcaa
    20161 tttgttcggc aacaatactt gctgcacggt gagcgcccca agctaaagga acactagccg
    20221 gtagatcgac atgtcgataa tgtgatgttg caatatcgcc tattgcataa atgtttggaa
    20281 catttgtttc aaatttatcg tttaccggta tgaaaccttt tcgatcaagt ttgatatttg
    20341 aactttcgat aaattttgaa ttggggtgag taccgacacc ttcaataatc atatcgtaat
    20401 gttcaacttt tcctgattta aatgtaattt catttccatt gatagcatca atttcctcat
    20461 ttaaacggta tggaatctcc cgcttatcta attcatcaag tataggttga ttcatgtcag
    20521 catccattaa tttatttatc ttatcagatc gatgaattaa agtagggtgt aaaccacgtt
    20581 cgtaaagatt ttcaagaact tctaatgaaa cataccctgc acctataacc aatactttat
    20641 caacttgatt tgctttgatg aattgatcga tagcatcagt gtcttctaaa tttctaagtg
    20701 taaatgtaat atcactttca aagccaaggc tatttgcact tgcaccaggg cttaaaatga
    20761 gtttatcgta agattcttca aattgttcgt tggtctttct atttaataca gttacagttt
    20821 gtctttcatc attgattgca ataacttcat gataagtttt tactgtaatt tgctttctat
    20881 cataaaattt ttcaggtgta tacgctaaag catattttct atcttcaaca acttcgccaa
    20941 tgacataagg caatgcacaa ttagcaaagc tcatatcacg atctttttca aaaataataa
    21001 tgtcactttc tttatctaaa cgtcgaattt ggctggcaca tgttgcaccg ccagcgactg
    21061 ctccgactac gactattttg ggcatcgtaa cttacctcct attgttttaa aatattataa
    21121 aatgattagt tataaattaa cagtaatatc taatatttaa attaaagaaa tcattcaaat
    21181 atcgaccaat gccatcttca ttattgttga atgtaatatt gttcgctaca tctttaagtt
    21241 cttgcaaacc attttccata gcaacaccat ggcgggcgta ctcaatcatt tcaatatcat
    21301 tatcttcatc accgaatgca ataatattat ttcggtcaat atttaaaaat tgtctaactt
    21361 gctcaatgcc tcttgcttta ttaataccaa gttttacaat ttcaatgaca gggaatggtg
    21421 cgccccagcg tcgatgctca atatgatcgg cataaaaatg agtaagcata tttttgattt
    21481 caggtatttt actttcttcg gcttcaatta aaattgaggt aggggattct ttcaagtgga
    21541 caagtaaatt accagtttga attcttggat tacccattga aaaaccttca aataatcttg
    21601 gatcatgatt gttaatgaaa acataatctt tcacttctgc tataatattc gatacttgat
    21661 attgttgtaa tccttgaata atgttttgtg cgatgcctaa atctaaaatt tcatggcaag
    21721 ttttgaagtt tttatcttta gggtgatgta cgtaagcgcc attaaaatta acaattggtg
    21781 tcgttaaatt taattcatga taatacattt gacttgcacg ataaggtctg ccagtcgcaa
    21841 tcataatttg gtgtccacgt tgttgtaatt catttaatac ttgtttagta tatgatgaaa
    21901 tttctttgtt atcgtttaat aatgttccgt ctaagtctag acatattaaa tgtggttgca
    21961 tatctctctc ctcataagtt gcttagttca tatagataca tcatagcatt ttattggcgt
    22021 tttgtcggat atttgatata ttatgaataa tatgacatta aagaggtgat atggatggaa
    22081 gaggcattga aagatagtat cttaggtgca ttagaaatgg taattgaccc tgaattagga
    22141 attgatatcg ttaatttagg tttagtatac aaagtgaatg ttgatgatga aggcgtatgt
    22201 acagttgata tgactttaac atcaatggga tgtccaatgg gacctcaaat tattgatcaa
    22261 gttaaaacag tattagcaga gattcctgaa attcaggata ctgaagtgaa tatcgtatgg
    22321 agtccacctt ggacaaaaga tatgatgtca cgttacgcta agattgcact tggtgtgagc
    22381 taacataaac gtgcattgcc tgtagaattt cttttagaaa ttctctgtgt tgggtccccg
    22441 cagtcaatat aacattgtag agtataattc attgtgaata agctcccttc aaagtagaca
    22501 ttgaaaaatg aaaattttga agggagcctt atttatgttc taggttctga tttcattttg
    22561 aaaatttata tctaacttgt ttcaaaaaat atgaattaag acagtgactt gcacttccaa
    22621 gagtgcacaa ttcattttct agttgaatat tttcttgaaa atttttataa taaattgaat
    22681 ttatattaca gttatattac aatacataat acttcatagt ttttaagttg ccgagttgca
    22741 ttacaaattg gatttcgaag taagaatcat cattggtaat ttttttaatt taacagtatt
    22801 ttagtcaata tgattttgat gatgtcgtaa ttcaataata tacatatgca tttcaatatt
    22861 cttttaaaca gcataactaa atttaattaa gcatctaaga agaacagttt taaaagggaa
    22921 gaatgcaaaa atgaacaaaa caaagggttt tacaaagtat aagaaaatga gatatatgcc
    22981 agggctcgat ggtttgaggg caatcgctgt tctaggaatt attatttacc acttaaacaa
    23041 gcaatggttg acaggtggct ttttaggtgt ggatacattt tttgtgatct ctggttattt
    23101 aattacaagc ttattactca aagagtatga tgacacaggt atcattaaat tgaaaagctt
    23161 ttggatacgt cgtttaaaac gtttattacc agcagtcata gttttattaa tggttgtagg
    23221 gacagcaacc ttattattaa aatcagataa tatcattagg gttaaacatg atattattgc
    23281 tgcgatattt tatgtatcaa actggtggta tatagcaaaa gatgttaatt attttgagca
    23341 attttcattt atgccattaa agcatttatg gtctttagca attgaagaac agttttacat
    23401 atttttccca gttattttgg ttacattatt gttaacaatt aaaaagcgat acaaaatagg
    23461 atttattttt tggggagtat caataatttc tttagggtta atgatgttta tctacagtat
    23521 taatggggat cattcacgag tgtattttgg tacagatact agattacaga cattgttact
    23581 gggtgttatt ttagcttttt tatggccacc gtttaaattg aaaaatgatc cacctaaagt
    23641 tgtaaaatat gttattgata gcataggtag tttatcattt atagtactta tattattatt
    23701 tttcattatt aatgatgaga cgaattggat atatgatggt ggtttctatt taatatccat
    23761 attaacgtta tttattattg ccagtgtcgt tcatccatct acatggatag cgaagatatt
    23821 ttcaaatcca gtgttagtat ttatcgggaa aaggtcttat agtttatatt tatggcattt
    23881 tgcagtaatt agtttcgtac atagttacta tgtagatgga cagatacctg tatatgtgta
    23941 ctttatagat ataagtttaa caattatatt tgcagagcta tcatatcgct ttatagaaac
    24001 tccatttaga aaagaaggta ttaaagcttt aaattggcga ccttcttata taccacaatt
    24061 tataagaatg gcaattgtag taaccttgtt aattccattt atgttgattt tagtaggtgc
    24121 attcaataaa tatggtaaag acattattgg agaaaaagcg aatagctttg ataccactat
    24181 tgaagataat tatttaatgc ggatagcacc aattgataac attcacattg atggcttagt
    24241 aagtgagaag aaaaaggaat cttccgacgt atataataat attaaacctc ttttaatcgg
    24301 tgattcagta atggttgata tcggtgagtc atttaagtca tcagttccta agtctagaat
    24361 tgatggctta gtaagtgaga agaaaaagga atcttccgac gtatataata atattaaacc
    24421 tcttttaatc ggtgattcag taatggttga tatcggtgag tcatttaagt catcagttcc
    24481 taagtctaga attgatggaa aagtagggcg tcaattgtat caaaccttac ctttagttaa
    24541 agcgaattat tcacaatata aaaaatcatc tgatcaagtc gtattagaat taggtacaaa
    24601 tggcgacttt actgtcaaac agctcgacga tttacttaat caatttggaa aagccaagat
    24661 ttatttagtt aatacacgtg ttccaagaat ttatgaggca aatgtaaatc gattattagc
    24721 tgacgcggcg aaacgaaagt ccaatgtcac attaattgat tggaataagc gatcacaagg
    24781 acatagtgaa tattttgcac cagacggtgt acatttagag tacaaaggag tcctagcttt
    24841 aaaagatgaa atattaaaag cacttaaaaa gaaataacat atgtttaata agtctagtta
    24901 atgtgtaacg taacattagc tagatttttt tattcaaaaa aatatttaca aatattagga
    24961 aatttaagtg taaaagagtt gataaatgat tatattggga ctataatata attaaggtca
    25021 aagaaagtca aagtcaaaag tgcaacttga ccaactctac aaattagagg tgaaattata
    25081 tggatataaa taaaatgaca tatgctgttc aaagtgcttt acaacaagca gttgaactga
    25141 gtcagcaaca taaattacaa aatatagaaa ttgaggcaat tttaagcgct gccttaaatg
    25201 aaagtgaaag cttatataaa agtattttag aacgagcaaa tattgaggta gatcaattaa
    25261 acaaagctta tgaagacaaa ctaaacacgt atgcatctgt agaaggtgac aatatacaat
    25321 atggtcaata tattagccaa caagcaaacc aattgataac taaggctgaa tcatacatga
    25381 aagaatatga agatgaatat atttcaatgg agcatatttt acgttcggca atggacattg
    25441 atcaaacaac aaaacattat ataaataata aagtagaagt tatcaaagaa attattaaaa
    25501 aagtaagagg gggaaatcac gtgacatcac aaaatccaga agttaattac gaagcattag
    25561 ctaaatatgg ccgcgactta gtagaagaag ttagacaagg taaaatggat cctgttatag
    25621 gaagagatga agaaattcga aatacgattc gtattttaag tcgtaaaact aaaaacaacc
    25681 ctgtgctcat tggtgaacca ggtgttggta aaactgcaat tgttgaagga ttagcgcaac
    25741 gtatagttaa gaaagatgtg ccagaatcat tattagataa aactgttttt gagttagatt
    25801 taagcgcatt agtagcgggc gctaaatatc gtggtgaatt tgaagagaga ttaaaagcag
    25861 tcctaaaaga agttaaagag tctgatggta gaattatatt atttattgat gaaatccata
    25921 tgcttgtagg tgctggtaaa acagatggtg ccatggatgc aggcaacatg ctaaaaccaa
    25981 tgttagcacg aggagagtta cattgtattg gtgcaacaac tttaaatgaa tatcgagaat
    26041 atattgaaaa agattcggca ttagagcgtc gtttccaaaa agtagcagtt agtgagcctg
    26101 atgttgaaga tacaatttca attttacgtg gtttaaaaga acgatatgaa gtgtatcatg
    26161 gtgtgcgtat tcaagataga gccttagttg ctgccgctga attgtctgat cgttacatca
    26221 ctgatcgttt tttaccagat aaagcgattg atttagttga ccaagcatgt gcaacaattc
    26281 gtacggaaat gggatcaaat ccaactgaat tggatcaagt taatagacgt gtcatgcaat
    26341 tagaaattga agaaagcgca cttaaaaatg aatctgacaa tgcgagcaaa cagagattac
    26401 aagaactaca agaagagctt gccaatgaaa aagagaaaca agcagcactt caatctcgtg
    26461 tagaatcaga aaaagaaaaa atagcaaatt tacaagaaaa acgtgcgcaa ctagatgaaa
    26521 gtagacaagc gttggaagat gcacaaacaa ataacaattt agaaaaagct gctgaactac
    26581 aatatggaac aattcctcaa ttggaaaaag aacttagaga attagaggat aatttccaag
    26641 atgagcaagg tgaagataca gatcgaatga ttcgtgaagt tgtaacagac gaagaaattg
    26701 gcgatattgt cagccaatgg acaggcatac cagtttcaaa attagttgaa acagaacgtg
    26761 aaaaattact tcacttaagt gacatcttgc ataaacgtgt tgtaggtcaa gataaagcgg
    26821 ttgacctggt ttcagatgca gtagttagag caagagcagg tattaaagat ccaaacagac
    26881 ctattggtag tttcttattc ctaggtccaa ctggagtagg taaaactgaa ttagctaaat
    26941 cattagctgc atcattattt gattctgaaa aacatatgat tcgtattgat atgagtgaat
    27001 atatggaaaa acatgcagta tcaagattga taggggcacc tccaggatat attggacatg
    27061 atgaaggggg tcaattaact gaagcggttc gtcgtaatcc atactcagtt atcttattag
    27121 atgaggttga aaaagcgcat actgacgtct ttaatgtatt attgcaaatt ttagatgaag
    27181 gccgtttaac tgattctaaa ggacgtagcg ttgattttaa aaatactatt attattatga
    27241 caagtaatat tggatctcaa gttttattag aaaacgtaaa agagactggt gaaattacag
    27301 aatcaacaga aaaagctgtt atgacaaatt taaatgcata tttcaaacca gaaattttga
    27361 atcgtatgga tgacatcgta ttatttaaac ctctatctat tgatgacatg agtatgattg
    27421 tagacaaaat attaacgcaa ttaaatataa gattattaga acagcgaatc tcaattgaag
    27481 tttctgatga tgctaaagct tggctaggtc aagaagctta tgaacctcaa tacggtgcaa
    27541 gaccattaaa acgttttgta caacgccaaa ttgaaacacc attagcacgt atgatgatta
    27601 aagagggatt cccagaaggt acaacgatta aagttaattt aaattcagac aataacttaa
    27661 cgtttaatgt tgaaaaaatt catgaataaa attgaaccaa gaatgtgatg attaatcgca
    27721 ttcttggttt tttagatttg aaatttatta taattgttca ttggcaatat actttttaaa
    27781 tgatttaata aaaaccaata tttctgggct ttcttttttg ctgtatatat atgtaaatga
    27841 aataggcgct tgtaaaattt tcgtgttaat aaccgaaata ttgtaatcac tatctgttgt
    27901 tatataaata ggcaggaatg atataccttg attcatttcg attaatttaa ttgaagtatg
    27961 cacatcattg atagatagaa attgtgcttt tccataaata tttaaaatat tatttttaag
    28021 tgatgaccaa tattctggat ggttatcact tattattttg tatttttcaa ataaagatgc
    28081 ctcagttaga agatgattat tctctttatt gggagcaatc aatacaattt taccttcgca
    28141 tactttttca gaatgaactt ctcttagttt aggttgattt ctgctaatcc cgatgtcata
    28201 cgtatgatta ttaatatctt tttcaatatt ttcatttttg acatggagag aaacatcgat
    28261 aaacggatgc tcgttaaaga aagattttaa aaatttgggc ataatgaatg tcgcgatata
    28321 tgaagacacg acaacattta atttcgattg aaacatcgtt tttttaagtt ggatatgttt
    28381 gatgccactt tcatattgtt caataaaact ttgcgcaatt ggaagaaatg tatgaccatc
    28441 ttcagtcaag ataatttgat ttttataagt ttcaaatagt ttcacattga gatgctgttc
    28501 taaattttta atttgcttat gtatagaagg tatagtgaga ttaatttctt cactagctaa
    28561 tcgatagttt aacgtcttcg ctaaaatgac aaatgtatag taccaatcca aattcatgaa
    28621 cttacctctt tcaaaaaagt taataattca ttagataata tttaattttt attgcataaa
    28681 aataatatta atattatatc agaggttatc gagggggtga agtaatatga ttcgaattca
    28741 agataataca ataagggatg gtatgcaaca aagtaatgtt cgaaaaagtc taattataaa
    28801 aaaagaagta ttgaaacaaa ttaacaagtt aaatataaat tctgttgaag taggcatgtg
    28861 tacaactatc gaggatgaat ttaatattca tcaattcaga gacattttaa gtcctgaaaa
    28921 agaattagta gtattgacta ggcttaatga aaaagaaata aaaaaaatag tcaaattgaa
    28981 aattcataat ttagtggtaa aaatactatt gccaatatct gacttgcata taaaagaaaa
    29041 gcttaatttt tcaaataaat attatattca gaaaatcaaa gactgcttgg atatattaaa
    29101 gaaagataaa aaaggagtag atatttgttt tgaagatgca acaaggactt ctagagaaaa
    29161 attgaaagaa tacatggaaa ttatttcaaa atatcaagtt agaacagtta catttgcgga
    29221 cactgtagga tgttcgacac cattagaata cggagatatt tttaattact ttgtaaaaaa
    29281 atattctaac ataatttttt ctgctcattg tcataacgat ctagggttgg ctactgcaaa
    29341 tacattagct gcaattttaa atggtgcaaa gcaaatagaa actacatttt tgggaattgg
    29401 tgagagagcg ggtaatgctc ctattgagga aataattact attttgacaa aaaaacaaat
    29461 agaaagtacg gaattcactt tacccgacgt atataaaact agtattaata tttctaaaat
    29521 tctcgatttt caaatatcag aaaacaaacc tataattggt gaaaatatat ttaaacatga
    29581 atcaggaatt catcaagatg gtactaaaaa aatataaata tgtatcaata tttagttcct
    29641 agtgatttag gattgaaaaa ttcacaagtt gttcagtttc caataagtaa tatttctagt
    29701 aagaaaatct tgcacaataa atttaaatca atagttaaca ctgaagaaat tgatgaaaat
    29761 atttctttct ataaacttgt gaacaagttt tcacctgaag tagcacctga agatacagtg
    29821 gatttacttc agataataaa aaggaggagt aaagatggaa attttaaatg attctgtaaa
    29881 aagttttgaa aaactttatt tacaattaca agatggtttt ccagtgattg ttcctactga
    29941 tactaattat aatttatgta gtttaccaaa caatgatctt tgtatcgata aaatatttga
    30001 atataaaaag agatcgaaag ataagccatt atcattattt attgataagc cagaggattg
    30061 gaaattgtat ggagataatc aaaatacgga aatagttgat aaactagttg aaatattttg
    30121 gcctggacca ttaaatatta ttttaaaaaa taaaacaagc tataattata tgctcaataa
    30181 ttcagatagt atagctatag gatgtgtgca aaataaaacg atgagaaggt ttatttcata
    30241 tattaattca cctatagcaa ttacttcagc aaatatctct ggaactgccg atgatatttt
    30301 aataactgaa aatgaagcaa ttaagcacat gggcgaaaat gtaagatata tgctaagaag
    30361 tcaaaataaa actaactata aaacatctag tacgattatt aaagtgacag ataataaaat
    30421 tgaattatta agagaaggag at
//
LOCUS       DAPDIM010000033        29917 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000033 DAPDIM010000000
VERSION     DAPDIM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 29917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29917
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.033"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(100..429)
                     /locus_tag="RFE25_001508"
     CDS             complement(100..429)
                     /locus_tag="RFE25_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816569.1"
                     /translation="MINETKYMRQQITNLIQIIDTIKYNTLMTDWNIQTHIYKFNQIV
                     TNELNKFKGFETSYIINENQVSYYEIITLLNKRPLRQVDYGNKIQYLNFYHTELSNAL
                     FAIKFAH"
     gene            478..1215
                     /gene="sdpB"
                     /locus_tag="RFE25_001509"
                     /pseudo
     CDS             478..1215
                     /gene="sdpB"
                     /locus_tag="RFE25_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501049.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease SdpB"
     gene            complement(1240..1932)
                     /locus_tag="RFE25_001510"
     CDS             complement(1240..1932)
                     /locus_tag="RFE25_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDU2816570.1"
                     /translation="MNKAERQNLIITAIQQNKKMTALELAKYCNVSKRTILRDIDDLE
                     NQGVKIYAHYGKNGGYQIQQAQSKIALNLSETQLSALFLVLNESQSYSTLPYKSEINA
                     IIKQCLSLPQTRLRKLLKRMDFYIKFDDTQHMTLPMLFSDILIYCTERNVMLVDHRVD
                     DNIKAENVIFIGLLCKHGHWHAVIYDIAQDKTAELEIENIIDISYSFGKTIQTRDISI
                     DNYHQFLNPIDS"
     gene            2317..3114
                     /locus_tag="RFE25_001511"
     CDS             2317..3114
                     /locus_tag="RFE25_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="HDU2816571.1"
                     /translation="MTDKTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVT
                     NVDKQIQQQFQQFLATHFPEHQLLAEEKSNEMITNEINHLWIMDPIDGTANLVKQQED
                     YCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGIKMEEPPSLKLEDAIISFN
                     AQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAE
                     LLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNANGGYQKYR"
     gene            3247..4194
                     /locus_tag="RFE25_001512"
     CDS             3247..4194
                     /locus_tag="RFE25_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDU2816572.1"
                     /translation="MKRSSKSKMSLPKKIFLWVFGILVILAIVAVVYVAAKIFITGNK
                     IHNPLDRNHSELRDKKVSLNDGDPFTIALFGVDSDADRKKKGGGERSDSIMILSINPK
                     TKKTEIVSIPRDTRAEIVGRGTTEKIAHAYAYGGPNMAVKSLEKLMNVPIDHYATIDM
                     DGLHNMIDSIGGVDVVSNDTFTVDGVRFTKGQQTHVNGDQALKFIRSRKEEGAGGDFG
                     RQQRQQIVLEAMANKIASPSSITHFNSLMNEIQNNVKTDLTLGDLNTIRSNYKDANDT
                     INKHQLSGQGGIQSDGLYYFIPSEQSKAESTKLLKDNLE"
     gene            4797..7751
                     /gene="fdhF"
                     /locus_tag="RFE25_001513"
     CDS             4797..7751
                     /gene="fdhF"
                     /locus_tag="RFE25_001513"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDU2816573.1"
                     /translation="MQEHLVVTLDGKDYLVEPGTNLLEFIKSQDTFVPSICYNESMGP
                     IQTCDTCTVEIDGKIERSCSTVIDRPMTVNTVNNDVKDAQKEALDRILEKHMLYCTVC
                     DYNNGDCEIHNTMDAWGLQHQTYEYKEKPYEKDYGPFYRYDPNQCILCGRCVEACQDI
                     EVNETIRIDWDREHPRVIWDNDVPINESSCVSCGQCATVCPCNAMMEVNMEGNAGYMT
                     DTEPGSLAAMIDLTKKAEPGYGPLFAISDSEAEMRKERIKKTKTVCTYCGVGCSFEVW
                     TKDREILKVQPSHDSPANKIATCVKGKFSWGHINSDQRLTKPLVRKNGEFHEVEWDEA
                     LNVIADNFTSIKEKYGPDALSFISSSKATNEESYLMQKLARQVIGTNNVDNCSRYCQA
                     PATKGLFRTVGHGGDSGSIEDLEKAAMSVLIGTNTAEAHPVIASRMKRAQKLFGQKIH
                     VFDIRKHEMAERADRFYQPKPGTDLAWLSAVTKYIIDHDLHDKAFIDEWVDDFDEYYK
                     SLETFTMAFAEEATGIPESELIKFAEECAKAESVVICWAMGITQQDIGSDSSTAISNL
                     LLVTGNYRRPGTGAYPLRGHNNVQGCSDMGSMPDKITGYQSIEADDIRAKFEKEYGVK
                     LNPKAGKDNHEMVEGIHDGEVHSLYLYGEDTGIVDSNINFVQAAFEKLDFMVVQDEFL
                     TFTATYADVVLPASPSLEKDGTFTNTERRIQRLYQALEPLGDSKPDWKIFQAIANRLG
                     FDWNYKHPSEIMDEVARLTPLYAGVSYDRLEGFNSLQWPVQPDGTDEPILYLEGFNFD
                     NGKAKLFPLSFDNYFKQDEIYDIHVNNGRLLEHFHEGNMTYQTPMIKYKVPRAFVEIS
                     PELAKDRGIHEGAEVKLISETGEAVLQVHVTDRVKGKEIYIPLNNDAMENGDLGAINL
                     LTNSDVDQYTDTPSYKRTSCRLEVITKRGKSPLNPNNFRVNKKRHPQYSVQVQKKWER
                     SDYVFPGNQVDK"
     gene            7751..8224
                     /locus_tag="RFE25_001514"
     CDS             7751..8224
                     /locus_tag="RFE25_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1641 domain-containing protein"
                     /protein_id="HDU2816574.1"
                     /translation="MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKL
                     IKTLDDAKLLDALNGAIRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDL
                     SDFLNKVNKGLHVANQASPNAKTTIRSLLGVLKDDDMNRSLTYMLNMLKGMSREE"
     gene            8452..8685
                     /locus_tag="RFE25_001515"
     CDS             8452..8685
                     /locus_tag="RFE25_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816575.1"
                     /translation="MLKTSAVISNTLLVIGLVCLFMMKLVLAITFFAVSLSISLVVFN
                     MMFRDRTTMKVIVNASFLIVILAIVVAYFLLSK"
     gene            8707..9483
                     /locus_tag="RFE25_001516"
     CDS             8707..9483
                     /locus_tag="RFE25_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDU2816576.1"
                     /translation="MKKNFKLRISTLLLIVILVVFAVLLIVNETKLFKNDVNYSFDEA
                     VSMQQGKGIVQTKEEDGKFVEANNNEIAKAMTISHKDNDMKYMDITEKVPMSESEVNQ
                     LLKGKGILENRGKVFLEAQEKYEVNVIYLVSHALVETGNGKSELAKGIKDGKKRYYNF
                     FGIGAFDSSAVRSGKSYAEKEQWTSPDKAIIGGAKFIRNEYFENNQLNLYQMRWNPEN
                     PAQHQYASDIRWADKIAKLMDKSYKQFGIKKDDIRQTYYK"
     gene            9794..10918
                     /locus_tag="RFE25_001517"
     CDS             9794..10918
                     /locus_tag="RFE25_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent monooxygenase"
                     /protein_id="HDU2816577.1"
                     /translation="MKIAIIGAGIGGLTAAALLQEQGHTIKVFEKNESVKEIGAGIGI
                     GDNVLKKLGNHDLAKGIKNAGQILSTMTVLDDKDRLLTTVKLKSNTLNVTLPRQTLID
                     IIKSYVKDDVIFTNHEVTHIDNETDKVTIHFAEQESEAFDLCIGADGIHSKVRQSVNA
                     DSKVLYQGYTCFRGLIDDIDLKHPDCAKEYWGRKGRVGIVPLLNNQAYWFITINSKEN
                     NHKYSSFGKPHLQAYFNHYPNEVREILDKQSETGILLHNIYDLKPLKSFVYGRTILLG
                     DAAHATTPNMGQGAGQAMEDAIVLVNCFNAYDFEKALQRYDKIRVKHTAKVIKRSRKI
                     GKIAQYRSRLFVAVRNRIMKMMPNALAAGQTKFLYKSKEK"
     gene            complement(11010..11963)
                     /locus_tag="RFE25_001518"
     CDS             complement(11010..11963)
                     /locus_tag="RFE25_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase family protein"
                     /protein_id="HDU2816578.1"
                     /translation="MEKVYVAGAIPEVGLKLLQEHFEVEMYEGKGLVDKDTLIKGVKN
                     ATALISLLSTNVDKDVIDAGKDLKIIANYGAGFNNIDIEYAREKSIDVTNTPKASTNA
                     TADLTIGLVLAVARRIVEGDQLSRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAV
                     ARRARAFDMDVLYTGPNRKEEKEREIGAKYVDLDTLLKNADFITINAAYNPKMHHLID
                     TEQFKMMKSTVYLINASRGPIVHEQALVQALKDNEIEGAALDVYEFEPDITDDLKSLN
                     NVVLTPHIGNATFEARDMMSKIVANAAISAVQGEKPQFVVN"
     gene            complement(12324..12824)
                     /locus_tag="RFE25_001519"
     CDS             complement(12324..12824)
                     /locus_tag="RFE25_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2816579.1"
                     /translation="MKKLVTATTLTAGIGTALVGQAHHADAAENYTNYNNYNYNTTQT
                     TTTTTTTTTTSSISHSGNLYTAGQCTWYVYDKVGGEIGSTWGNANNWAAAAQGAGFTV
                     NHTPSKGAILQSSEGPFGHVAYVESVNSDGSVTISEMNYSGGPFSVSSRTISASEAGN
                     YNYIHI"
     gene            complement(13061..13483)
                     /locus_tag="RFE25_001520"
     CDS             complement(13061..13483)
                     /locus_tag="RFE25_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4870 domain-containing protein"
                     /protein_id="HDU2816580.1"
                     /translation="MTTEMNDVTNHQPNRKSNDENIMAMLIYLLSLFTSIIGPLIIWL
                     LKKDESKLVDRAGKNYLNYTISYIIWSIVLVVITLIGVFLIATDISFIIIIGFIITFI
                     GILSIFAFSILSFVFTIIACVKYYNGQEYVIPLTIRFI"
     gene            13731..14813
                     /locus_tag="RFE25_001521"
     CDS             13731..14813
                     /locus_tag="RFE25_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD/NADP octopine/nopaline dehydrogenase family
                     protein"
                     /protein_id="HDU2816581.1"
                     /translation="MKIAIVGSGNGAVTAAVDMVSKGHDVKLYCRNQSISKFQNAIEK
                     GGFDFNNEGDERFVKFTDISDDMEYVLKDAEIVQVIIPSSYIEYYADVMAEHVTDNQL
                     IFFNMAAAMGSIRFMNVLEDRHIETKPQLAEANTLTYGTRVDFENAAVDLSLNVRRIF
                     FSTYDRSCLNDCYDKVSSIYDHLVKEESLIKTNLENGNPEVHPGPTLLNVGRIDYAGE
                     FALYKEGITKHTVRLLHAIELERLNLGRRLGFELSTAKESRIERGYLERDKEDEPLNR
                     LFNTSPVFSQIPGPNHVESRYLTEDIAYGLVLWSSLGRVIDVPTPNIDAVIVIASTIL
                     ERDFFEEGLTVEEIGLDKLDLEKYLK"
     gene            14908..16308
                     /gene="nhaC"
                     /locus_tag="RFE25_001522"
     CDS             14908..16308
                     /gene="nhaC"
                     /locus_tag="RFE25_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDU2816582.1"
                     /translation="MMKRKPTFLESISTMIVMVIVVVTGFVFFDIPIQVLLIIASAYA
                     TWIAKRVGLTWQDLEKGIAERLNTAMPAILIILAVGIIVGSWMFSGTVPALIYYGLDL
                     LNPSYFLISAFFISAVTSVATGTAWGSASTAGIALISIGNQLGIPPGMAAGAIIAGAV
                     FGDKMSPLSDTTNLAALVTKVNIFKHIHSMMWTTIPASIIGLLVWFIAGFQFKGHSND
                     KQIQTLLSELAQIYQINIWVWVPLIVIIVCLLFKMATVPAMVISSFSAIIVGTFNHHF
                     KMTDGFKATFSGFNDSMIHQSHISSSVKSLLEQGGMMSMTQILVTIFCGYAFAGIVEK
                     AGCLEVLLTTISKGIHSVGSLICITVICCIALVFAAGVASIVIIMVGVLMKDLFEKYQ
                     VSRSVLSRTLEDSSTMVLPLIPWGTSGIYYTNQLHVSVGEFFMWTVPCYLCAIIAIIY
                     GFTGIGIKKSSNSRLT"
     gene            16482..16724
                     /locus_tag="RFE25_001523"
     CDS             16482..16724
                     /locus_tag="RFE25_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816583.1"
                     /translation="MTKLIENLKASIFVSTLTKNLSMYSRFDMPKFGCVNGCMLFILY
                     YRVNRIGENRNFEIFTNSIFFIEIKKANKALETLLA"
     gene            complement(16742..17545)
                     /locus_tag="RFE25_001524"
     CDS             complement(16742..17545)
                     /locus_tag="RFE25_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2816584.1"
                     /translation="MKKIATATIATAGFATIAIASGNQAHASEQDNYGYNPNDPTSYS
                     YTYTIDAQGNYHYTWKGNWHPSQLNQDNGYYSYYYYNGYNNYNNYNNGYSYNNYSRYN
                     NYSNNNQSYNYNNYNSYNTNSYRTGGLGASYSTSSNNVQVTTTMAPSSNGRSISSGYT
                     SGRNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAARAGYTVNNTPKAGAIMQTTQ
                     GAYGHVAYVESVNSNGSVRVSEMNYGYGPGVVTSRTISASQAAGYNFIH"
     gene            18155..20110
                     /locus_tag="RFE25_001525"
     CDS             18155..20110
                     /locus_tag="RFE25_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2816585.1"
                     /translation="MTDNYSLHIYKSMKMSSVKEANLKIIYWLQGTGVVSINLQQYDV
                     KRNDVTVIMLNDLYQIDGHDDSVCCVVEVSAKTFLKFMNANYMMRGKILTNEVASTFR
                     ILIKYLIYSKIKQQSYNANDKIINYMCVELMSLNTYDGSRHLVAEEVHDYLTNNHHKK
                     INRKDVINQVSITNKALSDMFKATPYSNFIQYLNHIRLEHCLIDILTSKKPIEEIASS
                     HGFNHYSRFIHLFKETYGNTPKLIRKRYSPTSHSINHSQLVEIDKNIIELFDNTNQSS
                     SSMREIDIPFEPTKRSQMYQPKNIYIKGSNFYWMDYYTIKQIIQRLGVNLENLHIIVT
                     IDTSNELSIEQITLLLQKIVNYNVNVVFRIKHEYKELLTSTERGKIEKLVATIFNMTF
                     ESNRCKIAFLINDLNTTAIQKLKRLIDNYIGVFELIYHLEPKELNTHYDKEIDHLIDY
                     FILPLRQIEQVSIACSKIICDVDLINENNDLKEKITMSDFNKVTELLTNYTKFRGLIM
                     HMSIISEASKEINLTRLSIFIFIINILNQLRGIVIYQNDTMIVTKFKHEVQCVICLPA
                     ALLNENSDAIRLSCKGLQQFSHAKTKQIVLSIDKDNHTSENGVLVNDIMQQHSYWKAN
                     FIERNIYDHSLMVSSNSIVHLKYHLEI"
     gene            20136..20879
                     /locus_tag="RFE25_001526"
     CDS             20136..20879
                     /locus_tag="RFE25_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SarA family transcriptional regulator"
                     /protein_id="HDU2816586.1"
                     /translation="MSKFKVKRLTAHILMLKVINDMLKYSFHLTLTQVKLLNLLVKYD
                     NSDSNSASIDRLLKMKEIQSKMALLQMLSYLNNHQWLLKGRDQRDQRKLTISINKMHI
                     DKIEYMNNELSDYIERYFGQYTFDFSCDYVSYLLSSQELFRNLKCYLNMCQLTLEELY
                     VLGILNLHKGQLMVKELQGEFHHPIFAVSPILKCLILKGLVKKERCELDERRVIVTIK
                     REKFSKVTMLIQACYNYLEKGIQVKLNNK"
     gene            20943..21269
                     /locus_tag="RFE25_001527"
     CDS             20943..21269
                     /locus_tag="RFE25_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HDU2816587.1"
                     /translation="MILDNVNPNDLFPTEKKGPSVLGIIEYQVQGENEFEGAFIATNE
                     RLIMNVDMNGQFYYRSISYNEIEKIDYDGQTIMFKFNIGNVPMHDIKSDNVEMFVEYV
                     KQHMIV"
     gene            21697..22044
                     /gene="sarR"
                     /locus_tag="RFE25_001528"
     CDS             21697..22044
                     /gene="sarR"
                     /locus_tag="RFE25_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarR"
                     /protein_id="HDU2816588.1"
                     /translation="MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRS
                     ESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANI
                     QKLISELEEYIKN"
     gene            complement(22233..23069)
                     /locus_tag="RFE25_001529"
     CDS             complement(22233..23069)
                     /locus_tag="RFE25_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreD"
                     /protein_id="HDU2816589.1"
                     /translation="MDEQQWTGQLDLTVFFDGNRSVSRDIFFEKALKVIRPVYLNQST
                     IPTFYIVNVGGGYLDGDRYRMNVNVEDNAKVTLTSQGATKIYKTPSNHVEQYQTFNLK
                     DNAYLEYVADPIIAYENAKFYQHNTFNLNNSSSLFYTDILTPGYSKTGEAFKYQYMHL
                     INEIYIEDELVTYDNLLLNPNKQSINEIGYMEHYSHYGSAYFIHEDVNQKLIDSVYET
                     ISSYSNTFDCRVAISQLPTHGFAVRIFAYRTQIIEKILGTIQSYIAENIYDRKLDFLR
                     KY"
     gene            complement(23069..23683)
                     /gene="ureG"
                     /locus_tag="RFE25_001530"
     CDS             complement(23069..23683)
                     /gene="ureG"
                     /locus_tag="RFE25_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreG"
                     /protein_id="HDU2816590.1"
                     /translation="MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTK
                     EDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIES
                     GGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASL
                     EQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS"
     gene            complement(23696..24385)
                     /locus_tag="RFE25_001531"
     CDS             complement(23696..24385)
                     /locus_tag="RFE25_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreF"
                     /protein_id="HDU2816591.1"
                     /translation="MIDHTHLRLFQFCDSQFPTGAFSHSFGLETYIQRNIIHDDHTFI
                     AWLKMFLQEQLTYSDGLAMRLVYDALENDDTQKVLHIDKLMFVQNLPKETRVGAKQMG
                     TRMVKLALELYNSPWIAWYHQQMQDKKAKLNPAICFTMLGHHLGVDIETIIDYYLYQN
                     VSSLTQNAVRAIPLGQTAGQKIVTHMIPYIEETRKQIFELKEADFGMTAPGLELNQMA
                     HENVNVRIFIS"
     gene            complement(24378..24830)
                     /gene="ureE"
                     /locus_tag="RFE25_001532"
     CDS             complement(24378..24830)
                     /gene="ureE"
                     /locus_tag="RFE25_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreE"
                     /protein_id="HDU2816592.1"
                     /translation="MIVEEIQGNIANLSNSEKQKHVEKVYLENSDLVKRIQRVVTDHG
                     TEIGIRLKQPIDLQYGDILYADDHNMIIVDVNSEDLLVIQPRTLQEMGDIAHQLGNRH
                     LPAQFTETEMLVQYDYLVEDLLKSLGIPYVREDRKVNKAFRHIGHSHD"
     gene            complement(24843..26558)
                     /gene="ureC"
                     /locus_tag="RFE25_001533"
     CDS             complement(24843..26558)
                     /gene="ureC"
                     /locus_tag="RFE25_001533"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit alpha"
                     /protein_id="HDU2816593.1"
                     /translation="MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEA
                     TFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGN
                     AGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIG
                     GGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAI
                     GLKVHEDWGATPSALSHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYH
                     TEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDI
                     AFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPL
                     DGDFEHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPEL
                     VVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRA
                     LNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAATELPLTQ
                     RYFLF"
     gene            complement(26555..26965)
                     /locus_tag="RFE25_001534"
     CDS             complement(26555..26965)
                     /locus_tag="RFE25_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit beta"
                     /protein_id="HDU2816594.1"
                     /translation="MIPGEIITKSTEVEINNHHPETVIEVENTGDRPIQVGSHFHFYE
                     ANAALDFEREMAYGKHLDIPAGAAVRFEPGDKKEVQLVEYAGKRKIFGFRGMVNGPID
                     ESRVYRPTDENDAYAGVFGDNGAENVNKKGGKRS"
     gene            complement(26979..27281)
                     /locus_tag="RFE25_001535"
     CDS             complement(26979..27281)
                     /locus_tag="RFE25_001535"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit gamma"
                     /protein_id="HDU2816595.1"
                     /translation="MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELL
                     EGARDGKTVAELMSYGRQILNKEDVMDGVEHMITDIEIEATFPEGTKLITVHHPIV"
     gene            27541..28446
                     /gene="yut"
                     /locus_tag="RFE25_001536"
     CDS             27541..28446
                     /gene="yut"
                     /locus_tag="RFE25_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016266007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea transporter"
                     /protein_id="HDU2816596.1"
                     /translation="MKIIDVLLKNISQVVLISNKWTGLFILIGLFVADWTIGLAAIVG
                     SIIAYTFARFINYSEAEVNDGLAGFNPVLTAIALTIFLDKSGLDIVITMIATLLTLPV
                     AAAVREVLRPYKVPMLTMPFVIVTWFTILLSGQVKFVDTSLKLMPQNIETVNFSNNDR
                     IHFIQSLFEGFSQVFIEASVIGGVCILIGILIASRKAALLAVIASLLSFIIVALLGGN
                     YDDINQGLFGYNFVLMAIALGYTFKTAINPYISTFLGVLLTVVVQLGTTTLLEPFGLP
                     ALTLPFIIVTWILLFAGIKHDKVDA"
     gene            28663..29817
                     /locus_tag="RFE25_001537"
     CDS             28663..29817
                     /locus_tag="RFE25_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA/acyl-ACP dehydrogenase"
                     /protein_id="HDU2816597.1"
                     /translation="MNDMDNSFLITTEIQRKWIEKFKVIRDTFKAKAEYNDQHSQFPY
                     KNIEWLIKEGYGKLTLPKAYGGEGATIEDMVILQSFLGELDGATALSIGWHVSVVGQI
                     YEQKLWSQDMLEQFAVEINNGALVNRAVSEAEMGSPTRGGRPSTHAVKADDGYILNGV
                     KTYTSMSKALTHIIVAAYIEELESVGFFLVDRNLPGVEIADNWDVLGMRATESHDLIL
                     NDVKVPLKHLVETEKSKAPNGWILHIPSCYLGIAQAARNYAVDFAIQHSPNSIEGTIA
                     TLPTVQQNLGKMETLLLCARQFLWSTAKGYQQYKDDSQIRNPTSASKVMVMNQGLEVI
                     DLAMRIVGAKSLEMNRPLQRYYRDMRAGLHNPPMEDAAYTNIAKSITDTF"
BASE COUNT        10332 a         4241 c         5363 g         9981 t
ORIGIN      
        1 catctttaca atttgaagaa actttttaat tgtataattt atgtaataaa gtgaatttta
       61 ataaataact tgtttaaatg acattttatg aaaaataggt taatgggcaa atttaattgc
      121 aaataatgcg ttagatagtt ctgtatgata aaaattaaga tattgaattt tgttaccata
      181 gtcgacttgt cggaggggac gtttattaag tagtgttata atttcataat aggaaacttg
      241 attttcgttt attatatatg atgtttcaaa gcctttgaac ttattcaatt cattagtaac
      301 tatttggtta aatttataaa tatgcgtttg aatgttccaa tctgtcatta aagtattata
      361 tttaatcgta tcaatgattt gaatcaaatt agtaatttgt tgtctcatat acttagtttc
      421 gtttatcatg tagaagtacc tccaaaaatc aattattaaa caggaaagga tataacagtg
      481 gaaaatgaaa aaaagaaata cacgtttaaa gatatagcat ggagagattt gcttataatt
      541 ccaattatag gtgttatatt ttatgcactc acaattgcag cttacatagg accaattttg
      601 tttggttatt atgaaatcga tagtaatctg atatttgtag cgactatcac acaagcttta
      661 gcatatacga ttgggattgg cgcattttat ttatttcatt taaaagtgat gccatcaagg
      721 cttcgagctg gttttgcgta aatcaaaaaa tattggctta gattgtcaat aacgtatatt
      781 attgctctca tcttaattta tacatatgaa tatatgacac agtttctacc taaacatttg
      841 caatatagtg aaacagccaa tgaacttgag ctaaataaaa tgtttgaagt gcctgcattt
      901 ttacctgtag cattcttatt aattgtgatt gtaggtccaa tagttgaaga aatcgtattt
      961 agacatattt taattggaga attaggtaag aagtttaatt ttatagctat gagtattgtt
     1021 tcggtgttct tatttgcatt tattcatgtg actgatgcaa agtcgccgtt tgagtttggt
     1081 ccatatctca tactatccat catattagtt ttcacttatt taaaatctgg aagaaaccta
     1141 ggttcaacaa ttgcattaca tatagcaaat aattttgttt ctttcgttat atcagtaata
     1201 agtatttatg cgtagataaa accccatcga ctccatagtt taggaatcga tggggtttaa
     1261 aaattgatga tagttatcaa tggatatgtc tctggtttga atcgtcttac cgaatgaata
     1321 cgaaatatct ataatatttt caatttcgag ttcggcagtt ttgtcttgag caatgtcata
     1381 aatgactgca tgccaatgtc catgtttaca caaaaggcca ataaatataa cgttttcagc
     1441 tttaatatta tcatcaaccc tatgatctac taacatcaca tttcgttctg tacaataaat
     1501 taaaatgtcg gaaaacagca ttgggagtgt catatgttgt gtgtcatcaa atttaatata
     1561 aaagtccatg cgtttaagca attttcttaa gcgtgtttgt ggaagactta aacattgttt
     1621 tataattgcg ttgatttcgc ttttatatgg taatgtcgag tacgactgac tttcattaag
     1681 cactaaaaat aaggccgata attgtgtttc agataagttt aatgcaattt tagattgtgc
     1741 ttgttgtatt tggtaaccac catttttccc ataatgcgca taaattttaa caccttgatt
     1801 ttctaaatca tcaatatctc ttaaaattgt gcgtttggat acgttgcaat atttagctaa
     1861 ttctaaagcg gtcatttttt tattttgttg aattgcagta attattaaat tttgcctttc
     1921 agctttattc atgacagcca cctcctaaaa gatgatatat tacacaaagt ataacataag
     1981 agtgacaatg aggacatttt caatatcttt taaaaaaaat cgtaaaaatt ttttggaaaa
     2041 cgcttacatt ttaaaaaaga ttgtgctatg atattacttg taacaggggg agcgattaaa
     2101 caaaggggta gagctatata acagatagct tttaatcgtt caagttacat cacaacatct
     2161 tcaatattta ttacttactt tcctttctat ttgtcggcta gcacgtgact agccgatttt
     2221 tttatgcata aaatgaagaa gtcttcagtt gtattgttga ttcttttaat atagggtaat
     2281 aataaaatga taatgatatg agaagtggtg gacgaaatga cagataaaac attacagcaa
     2341 atagataagt taatatgttc gtggttgaaa caaatagaca atgttattcc gcaattaatt
     2401 atggaaatga ctacagaaac taagcgtcat cgatttgatt tagttacaaa tgtagataaa
     2461 cagattcaac aacaattcca acaattttta gcaacacatt ttccggaaca ccaactatta
     2521 gcggaagaaa aaagtaatga aatgattacg aatgaaatta atcatttatg gattatggat
     2581 cccattgatg gaactgccaa tttagtaaaa cagcaagaag attattgtat tatattggcg
     2641 tatttttatg aaggtaaacc aatgttatcg tacgtatatg attatccgca taaaaagctt
     2701 tataaagcaa tacgaggaga aggtgctttt tgtaatggaa ttaagatgga agaaccacca
     2761 tcgttaaaat tggaagacgc tattatatcg tttaatgcac aagtgatgaa tctagatacg
     2821 gtgcaagatt tatttgacgc ctcatttagt tatcgtttag ttggtgcttg cggattagat
     2881 tctatgcgag tggcaaaagg tcaatttggg gcacatatta atacaaatcc taaaccttgg
     2941 gacattgctg cacagttttt atttgcagaa ctattgaatc taaaaatgac gactttagat
     3001 ggtaaggcaa ttgatcattt aaagggtgca ccttttatta taagtaataa agcatgtcat
     3061 gaaacggtac ttaaaatttt aaatgcaaat ggtggttatc aaaaatacag atagatattc
     3121 tctagagata aaaaatgata aaaaatagtt atacgtctac agaagtatag taaaaaaatt
     3181 attttactat ataataaata gagaaaacag acaaagtatg taaggaatag taaaggagtg
     3241 gtgggattga aacgttcgtc taaaagtaaa atgagcctac cgaaaaaaat atttttatgg
     3301 gtattcggta ttttagtaat cttagcgatt gtagctgttg tgtatgtagc tgctaaaatt
     3361 tttattactg gtaataagat acacaatccg ttagatcgca atcattcaga attaagagat
     3421 aaaaaagtga gtttaaacga tggtgatcca ttcacaatcg ctttatttgg tgtcgattca
     3481 gatgctgatc gtaagaaaaa gggtggcgga gagcgtagtg atagtattat gattttatct
     3541 atcaacccta aaacgaagaa aactgaaata gtaagtatac cgcgtgatac aagagcggaa
     3601 attgttggcc gtggtactac tgaaaaaatt gcacatgcct atgcatatgg tggaccaaat
     3661 atggctgtta aatcacttga aaaattaatg aatgtgccaa ttgatcatta tgcgacaatc
     3721 gatatggatg gtttgcataa tatgatagat agcatcggcg gtgttgatgt agtaagtaat
     3781 gatacattca ctgttgatgg tgttcgtttt acaaaaggac agcagacaca tgtaaatggt
     3841 gatcaagcat tgaagtttat tagaagtcgt aaagaagaag gtgctggtgg tgactttggt
     3901 cgacaacaac gtcagcaaat tgtgcttgaa gcgatggcca ataagattgc aagcccatca
     3961 tcgattacac attttaatag tctaatgaat gaaattcaaa ataatgttaa aacagattta
     4021 acattaggtg atttgaatac gattagaagc aattataaag atgctaatga cacgattaat
     4081 aaacatcaat tgagtggtca aggcggcatt caaagtgacg gattgtacta cttcattcct
     4141 agtgagcagt caaaagctga aagtactaag ttattaaaag ataatctaga gtagtaaact
     4201 aagggaaaat aagttatcaa aattgtacac aaattaatta gatagaatga tctgtaaata
     4261 gaataacgaa tagaactaat agcccgtaaa tagaaggtga taacactttg tatttatggg
     4321 ctattttatt taatgcctga tttgattttt ataaattaat ccattacaaa tttaatttaa
     4381 agataaatat taccttctaa atggtagtag atatttatca aacttgggtt attaattttc
     4441 agaaaaaggg tatttataaa tagtataacg atttttaggt gaggtgatta ttaagtattg
     4501 tcattaataa ggttgtgaaa gatatgactg aaaagcgtga aacagataat tggaaaacta
     4561 ataatgataa ttattttcaa ttaaacaaaa agatgattta atttcgcgca aaatatttca
     4621 aataaaaatg attgtaaaaa ggcaaaatac aaaatttcac ttaacaacta gtacataaag
     4681 taatacaatt aaattaattc tatctgaaag atgtgtgggg catcgttatt ttaggtggat
     4741 atgagcaatt tattaaaagt catttacgga aaatatatat agacggggtg agtaatatgc
     4801 aagaacattt ggtggttaca cttgatggaa aagattatct tgtagaacca ggtacgaatt
     4861 tacttgaatt tattaaatca caagatactt ttgtaccttc aatttgttat aacgagtcga
     4921 tgggaccaat tcaaacatgt gatacatgta ctgttgagat tgacggtaaa attgaacgtt
     4981 catgtagtac ggtgattgat cgtccaatga ctgtaaatac tgtgaacaat gatgtgaaag
     5041 atgctcaaaa agaagcgctt gatcgaattt tagaaaagca tatgctgtat tgtacagtat
     5101 gtgattataa taatggtgat tgtgaaattc ataatacgat ggatgcatgg gggcttcagc
     5161 atcaaacgta tgaatataaa gagaagccat atgaaaagga ttatggccca ttttatcgtt
     5221 atgatccaaa tcaatgtatc ttatgtgggc gttgtgtaga agcatgtcaa gatatcgaag
     5281 tgaatgaaac tattagaatt gattgggatc gtgaacatcc acgtgttatt tgggataatg
     5341 atgtaccaat taatgaatcg tcatgtgtat cttgtggtca atgcgcaact gtatgtccat
     5401 gtaatgccat gatggaagtg aatatggaag gtaatgcggg ttatatgact gatacggaac
     5461 ctggttcatt agcagcaatg attgatttaa ctaaaaaagc agaacctggt tatggtccac
     5521 tatttgcaat ctcagattca gaagcagaaa tgcgtaaaga gcgtattaag aaaactaaaa
     5581 cagtgtgtac ttattgtggt gtgggttgtt catttgaagt ttggactaaa gatagagaaa
     5641 ttttaaaagt acaaccatca catgattctc cagcaaataa aattgcgact tgtgttaaag
     5701 gtaagttttc atggggacat attaattcag atcaacgctt aactaaacca ctagtaagga
     5761 aaaatggtga gttccatgaa gtagaatggg atgaagcttt aaatgtcatt gcagataatt
     5821 ttacatctat taaagaaaag tatggcccag atgcactatc attcatttct tcttctaaag
     5881 cgacgaatga agaatcgtat ttaatgcaaa aattagcaag acaagttatt ggcacaaata
     5941 acgttgataa ctgttcaaga tattgccaag cacctgcaac aaaaggctta tttagaacgg
     6001 ttggacacgg cggtgactca ggtagtattg aagatttaga aaaagcggca atgtctgtat
     6061 tgataggtac caatacagcc gaagctcatc cagttatcgc atcacgcatg aaacgtgctc
     6121 aaaaattatt tggacaaaaa atacatgtat ttgatattag aaaacatgaa atggcagaac
     6181 gtgcggatcg tttttatcaa cctaaaccag gtacggattt agcgtggtta agtgcagtga
     6241 ctaagtatat tattgatcat gatttacacg ataaagcatt tattgatgag tgggtagatg
     6301 attttgatga atattacaaa tcattagaaa catttacaat ggcttttgct gaagaagcaa
     6361 caggtattcc tgaatcagaa ttgattaaat ttgctgaaga atgtgctaaa gctgaatctg
     6421 ttgtaatttg ttgggcaatg ggtattacac aacaagacat tggtagtgac tcaagtacag
     6481 cgatttcaaa cttattatta gtaacaggta attatcgtcg tcctggtact ggtgcgtatc
     6541 cattacgtgg acataataat gttcaaggat gtagtgatat gggaagtatg cctgataaga
     6601 ttactggtta tcaaagtatt gaagcggatg atattcgcgc taaatttgaa aaagaatatg
     6661 gcgttaaatt gaatccaaaa gctggtaaag ataatcatga aatggtagaa ggtatacatg
     6721 acggagaagt acactcattg tacttatatg gtgaagatac gggtattgtg gattcaaata
     6781 ttaattttgt acaagctgcg tttgaaaaat tagatttcat ggtagtccaa gatgaatttt
     6841 taacattcac agcaacatac gcagatgttg tattgccagc aagtccttca cttgaaaaag
     6901 acggtacttt tacaaatacc gaacgtcgta ttcaacgttt ataccaagca ttagaacctc
     6961 ttggtgattc aaaacctgac tggaaaattt tccaagcaat tgctaataga ttaggatttg
     7021 attggaatta caagcatcct agtgaaatta tggatgaagt agcacgctta acacctctat
     7081 atgctggggt aagttatgat cgtttagaag gattcaatag tttacaatgg ccagtacaac
     7141 ctgatggtac tgatgagcct attctatact tagaaggatt caattttgat aatggtaaag
     7201 caaaattatt cccattatca tttgataatt actttaagca agatgaaatt tatgatattc
     7261 atgtaaacaa tggtcgattg ttagagcact tccatgaagg taatatgact tatcaaacac
     7321 caatgattaa atacaaagtg ccacgtgcat ttgttgaaat ttctccagag cttgctaaag
     7381 atagaggcat tcatgaaggt gcagaagtta agctgatttc tgaaacagga gaagcggtat
     7441 tacaagttca cgtgacagat cgtgttaaag gtaaagaaat ctatattcca ttaaataatg
     7501 atgcgatgga aaatggagat ctaggtgcaa ttaacttatt aactaatagt gatgttgatc
     7561 aatacacgga tacaccatct tataaacgta ctagctgtcg tttggaggta attacgaaac
     7621 gtggtaagtc accgttgaac cctaataatt tccgtgtcaa taaaaaacgt catccgcagt
     7681 acagtgttca agtacagaaa aaatgggaac gttcagatta tgttttcccg ggaaatcagg
     7741 tggataaata atggctgaga gaatatcttc taaaattaga cgcttagaaa aatcagaaga
     7801 acaaattaag ttagaaagtt taaatgaagt tacagaggca attgcagcga ataaagatag
     7861 tatattaaaa gcaatcaagc ttattaaaac attagatgat gcaaaactat tagatgcttt
     7921 aaatggtgca attcgaggac gtcaagtcat cataaataaa tttgcagttg aacttaataa
     7981 agatatttat acagggctat tatctaatat ggcttcaatg gtatttttat taggtgaact
     8041 caatgtatca gatttaagcg acttcctaaa taaagttaat aaaggattac acgttgccaa
     8101 tcaagcgagt ccaaatgcta agacaactat aagaagtcta ttgggcgtat tgaaagatga
     8161 cgacatgaac cgtagtttaa catacatgct taatatgcta aaaggtatgt ctcgagaaga
     8221 ataacattac aatgaaaaag tgtttctaca tgcaagcagt gtaggagcac tttttttaat
     8281 ttttgtaaaa attaaaaagg gtgtttttga tggaataaat gaataatatt gaaaaacaaa
     8341 aaaatcacgt gctattgtga atcaatcatc gacaggccta tgaaacatca tgtattatta
     8401 tgattatgta agttatttaa ataaaaaggg tgagtgcata ttaattcgag aatgttaaaa
     8461 acgtcagctg taatttctaa tacattatta gtcataggtt tagtctgtct atttatgatg
     8521 aaattagtgt tagctattac tttttttgct gtttcattat caattagtct agttgtcttt
     8581 aatatgatgt tcagagatag aacaacgatg aaagtaatcg ttaacgcttc ttttttaatc
     8641 gtaatattag cgattgtagt ggcatatttt ttattgtcta agtaagaaaa atgaggtttt
     8701 gtctatatga agaagaattt caagttacgc atttcaacgc tactattgat agttatttta
     8761 gttgtttttg ctgtattact catcgtgaat gaaactaaat tgtttaaaaa tgatgtgaat
     8821 tactcttttg atgaggctgt ttcaatgcaa caagggaaag gtattgtaca gacaaaagaa
     8881 gaggatggta aatttgttga agcaaataat aatgaaattg ctaaagcaat gactatttca
     8941 cataaagaca atgatatgaa gtatatggat atcacagaaa aagtgccaat gtcggaatct
     9001 gaagttaacc aattgctaaa aggtaagggg attttagaaa atcgagggaa agtttttcta
     9061 gaagctcaag aaaaatatga ggttaatgtc atttatcttg ttagccatgc attagtagaa
     9121 acaggtaacg gcaaatcaga attagcaaaa ggcattaaag atgggaaaaa acgctattac
     9181 aacttttttg gtataggagc attcgatagt agtgctgttc gtagtgggaa aagttatgct
     9241 gaaaaggaac aatggacatc accagataag gcgattattg gtggtgcaaa gttcattcgt
     9301 aatgaatatt ttgaaaacaa tcaactgaat ttatatcaaa tgcgatggaa tccagaaaat
     9361 cctgcgcaac atcaatatgc gagtgacatt cgatgggcag ataaaattgc caaattaatg
     9421 gataaatcct ataagcagtt tggtataaag aaagatgata ttagacaaac atattataaa
     9481 taagacatcg gtgcttaaag gagctggaac aatttattgt ttcgagctcc tttagcgcat
     9541 tctgagtgtg ttagttaaat ggattttaac ctaacaaaaa acgctatata gcatcaaata
     9601 tgctatatcc cacatcattg ttacaaatgt acatgatgta aatgaatatt gctgtctaaa
     9661 tgtgcatgta atgtacaatg gtgcagataa tacacttaag tccttaaaaa tgaaacgtta
     9721 gttccaagag tcatttttaa acaatagtgc atgtgataaa atagaaaaga atgaaaaata
     9781 tagaggtgac aatatgaaga tagcaattat aggtgcaggc atcggtggat taacagctgc
     9841 tgcattatta caagaacaag gtcatactat taaagtcttt gaaaaaaatg agtcagttaa
     9901 agaaattggc gctgggattg gtatcggaga taatgtgctt aaaaaactag gtaatcatga
     9961 cttagctaaa ggtattaaaa atgctgggca aatcttatct acaatgacag tgttagatga
    10021 caaagatcgc ctgttaacta ctgttaaatt aaaaagtaat acattgaatg tgacgttacc
    10081 acgccaaaca ttaattgaca ttattaaatc ttatgtaaaa gatgatgtaa tatttacaaa
    10141 tcatgaagtt acgcatatag ataatgagac agataaagtt accatacatt tcgcggaaca
    10201 agagagtgaa gcatttgatt tatgtattgg tgctgatgga attcattcta aagtgagaca
    10261 atctgtaaat gctgacagta aagtattata tcaagggtat acatgcttta gaggtttaat
    10321 tgatgatatt gatttaaagc atccggattg tgcaaaagaa tactggggaa gaaaaggaag
    10381 agtaggtatt gttccgttat taaataatca agcatattgg ttcattacaa ttaactcgaa
    10441 ggaaaacaat cataaatata gttcgtttgg taaacctcat ttgcaagcat actttaatca
    10501 ctatccaaat gaagttagag agatcttgga caaacaaagt gaaacaggta tcttattgca
    10561 taatatttat gatttgaaac cactcaaatc ttttgtttat ggtcgtacta ttttactagg
    10621 agatgcagca catgcgacaa cgcctaatat ggggcaaggt gctggacaag caatggaaga
    10681 tgctatcgta ttagtaaatt gttttaacgc atacgacttt gaaaaagcat tacagcgtta
    10741 tgataaaata cgtgtcaaac atactgcaaa agtaattaag cgttctagaa aaatcggtaa
    10801 aattgcccaa tatcgtagtc gtttatttgt tgcagttaga aatcgtatta tgaaaatgat
    10861 gccaaatgca ttagcagctg gacaaactaa attcttatat aaatcgaaag agaaataata
    10921 caacaatatg aaaacccccg tatgttgaaa cgagagctca acatatgggg gttcttgttt
    10981 ttataatgtt attataataa attcaattat tagttaacga caaattgtgg tttctcacct
    11041 tgaacggcac taattgcagc attagcaaca attttagaca tcatgtcacg tgcttcaaat
    11101 gtagcattac caatatgcgg tgttaatact acattattaa gtgattttaa gtcatcggta
    11161 atatctggtt caaattcata tacatcaagt gcagcacctt caatttcatt atctttcaat
    11221 gcttgcacta gtgcttgttc gtgcacgatt ggaccacgag aggcattgat taaatacacc
    11281 gtagatttca tcattttaaa ttgttctgta tcaattaaat gatgcatttt aggattataa
    11341 gcagcgttga tagtgataaa atctgcattc tttaatagtg tatctaaatc tacatatttt
    11401 gcaccgattt ctcgttcttt ttcttctttg cgattaggtc cagtgtatag cacatccatg
    11461 tcaaatgctc ttgcacgacg agctactgca ctaccaattt cacctaaacc gataatgccg
    11521 attgttttcc cagatacttc tctacctctg aaaaataaag gtgcccatcc gtcaaatcca
    11581 gttgtacgtg ataattggtc cccttcaaca atacgacgag ctactgcaag tactaatcca
    11641 attgttaaat cagcagtcgc gtttgttgat gctttaggtg tgtttgtaac atctatactt
    11701 ttttctcggg catactcgat atcaatatta ttaaaaccag cgccatagtt ggcaatgatt
    11761 tttaagtctt taccagcatc gataacatct ttatcaacgt ttgtagataa taaactaatt
    11821 aaggcagtcg cgtttttaac acctttaatt aaagtgtctt tatcgactaa tcctttacct
    11881 tcatacattt caacttcaaa atgttcttgt aaaagtttta accctacttc tggtattgca
    11941 ccagcaacat aaactttttc cataaaagat cactcctttt atctttgtat agtagaagat
    12001 tagacagtat acaactatgt catgatgtct tgtgtatcaa tgatgtaagc gcgtactttt
    12061 gatggaggtg atataactta ggcactgtag aactatgaat tttgtaatgt ggaaaaactg
    12121 gatcaattaa attagataac gtagttttaa agttaatagt attagaaaaa attaatatta
    12181 taaatatggg ggaaatataa ataagtaggt ggcaacgaaa aatagcaaaa aaagagcttc
    12241 tcctataaag gaaagctcaa agttttttga tgacatatgt actagaatta agtttcaaga
    12301 caatatgtat catcgtgttt atattaaata tggatgtagt tgtagttacc tgcttcactt
    12361 gcagaaatag ttctagaact tactgagaaa ggtccgccac tataattcat ttctgaaatt
    12421 gtaactgaac catcactgtt tacactttct acatatgcaa cgtgaccaaa tggtccttca
    12481 gaagattgta ggatagcgcc tttagaaggt gtatgattta ctgtgaatcc agcaccttgt
    12541 gcagcagcag cccaattatt agcatttccc caagtagaac cgatttctcc gcctacttta
    12601 tcatatacat accaagtaca ttgtcctgca gtgtataagt taccagaatg tgaaattgat
    12661 gatgtagttg tcgtagttgt tgtagtcgtt gtagtttgag tcgtgttgta gttatagttg
    12721 ttgtaatttg tataattttc agcagcatct gcatgatgtg cttgacctac taatgctgta
    12781 ccgattcctg ctgttaacgt agttgctgtt actaattttt tcatgaataa agtcctccaa
    12841 agttctatat ctttttttat aaataaaacg tagcgactgt tttattctca catctcgaat
    12901 tgatgacaat agttacttta acaaaattaa tgcttcttgt ggggaatgtt attgatttgt
    12961 aaaagaataa aaaaactttg actaattttg taataaaaat tagtcaaagt tacaatgaga
    13021 ttaacagata attaatagga aatatttatt tgtaatatgt ttaaataaat cgaattgtta
    13081 aaggtattac atattcttgg ccattataat atttgacaca cgcaataatt gtgaatacaa
    13141 aagataatat tgagaaagcg aatatggata aaataccgat aaatgtaatg atgaaaccta
    13201 taatgataat gaaactaata tcggtagcaa ttaggaaaac gcctattaaa gtgataacga
    13261 ctaaaacgat agaccaaata atataagaaa tcgtatagtt aagataattt tttccagcac
    13321 gatcaactag tttcgattca tcttttttca ataaccatat tatcagtgga ccaataatag
    13381 atgtgaataa acttaataaa tagataagca tcgccataat gttctcatca ttggatttgc
    13441 gattcggttg atgatttgtt acgtcgttca tttcagttgt catattagac actcctttga
    13501 aaattgtaat attatcttta actataacaa aatataatca aaaataaaca tgtttattaa
    13561 acaattatta aaaataaaaa taattggtgg acgtcggcgt ttaaataggt taatttaagg
    13621 ttatatatac ttaacattta taatgatgcg taatgaattc gcatcatttt tatattgtct
    13681 tacgtataat ttgtttttaa ttttaaccaa agatagaaag agggttgttt atgaaaatag
    13741 caattgtagg atcaggaaat ggcgcagtta cggcagcagt agatatggtg agcaaaggcc
    13801 acgatgttaa attatattgt cgtaatcaat ctataagtaa gtttcaaaac gcaatcgaaa
    13861 agggcggatt tgattttaat aatgaaggtg atgaacgttt cgtaaaattc actgatatta
    13921 gtgatgatat ggaatatgtt ttaaaagatg ctgaaattgt tcaagtgatt attccatctt
    13981 catacataga gtattatgct gatgtaatgg cagagcatgt aactgataat cagttgatat
    14041 tcttcaacat ggctgcagca atggggtcaa ttcgttttat gaatgtttta gaagatagac
    14101 atattgaaac aaaaccacaa ctagcggaag ctaatacgtt gacgtatggt acgcgtgtcg
    14161 attttgaaaa tgcagcagtt gatttatctc taaatgtacg tcgtatcttc ttttcaacat
    14221 atgatagaag ctgtctaaat gattgttatg acaaagtttc aagtatttat gatcatttag
    14281 taaaagagga aagcttaatt aaaacaaatc ttgaaaatgg taatcctgaa gtgcatccag
    14341 gaccaacatt attgaatgtc ggtcgcattg attatgctgg cgagttcgct ttatataaag
    14401 aaggaattac taaacataca gttagattac ttcatgcaat cgaattagaa cgtttaaatt
    14461 taggccgtag attaggtttt gaattatcaa cagctaaaga atcacgtatt gaacgtggtt
    14521 atttagaacg tgataaagaa gatgaaccat taaatcgttt gtttaataca agcccagtat
    14581 tttcacaaat tccaggacca aatcatgtag aaagcagata tttaactgaa gatattgcat
    14641 atggtttagt actatggtca agcttaggtc gtgttattga tgtaccgaca ccaaatatag
    14701 atgcagtaat tgtaattgca tcaaccattt tagagagaga cttctttgag gaaggcttaa
    14761 cagttgaaga aattggttta gataagcttg atttagaaaa atatttaaaa taaatgatgg
    14821 cttgaagata gaaaaggata tagcattatg caaaagcaat aaattgaaga aaagaggttt
    14881 ctcatcaata agcgaagggg acgatagatg atgaaaagaa aaccaacctt tttagaatca
    14941 atttcgacaa tgattgtaat ggttattgtt gttgtaacag gctttgtgtt ttttgatatt
    15001 ccaattcaag tattattaat tattgcctca gcatatgcca catggattgc aaaacgtgta
    15061 ggcttaacat ggcaagattt agaaaaaggc attgcagaac gtttaaatac tgcaatgcct
    15121 gcaattttaa ttatactagc ggtaggaatt atagtaggca gttggatgtt ttctggcaca
    15181 gtgccagcct tgatttatta tggcttagat ttattgaatc caagctattt tttaatatca
    15241 gcctttttta taagtgctgt tacatctgta gcaactggta cagcatgggg ctctgcatca
    15301 actgcaggga ttgcacttat ttctattggt aatcaattgg ggattcctcc agggatggca
    15361 gcgggtgcta ttatagcagg ggctgtgttt ggcgataaaa tgtcaccatt atcagataca
    15421 actaatttag cggcacttgt tactaaagtt aatatattta aacatataca ttcgatgatg
    15481 tggacgacga tacctgcatc aatcataggt ttattagtat ggtttattgc tggatttcaa
    15541 tttaaagggc attcaaatga taaacagatt caaactttgt tatcagagct tgcacagatt
    15601 tatcaaatta acatatgggt ctgggttccc ttaattgtga tcattgtttg tttgctattt
    15661 aaaatggcta cagtgccagc tatggtaata tcaagctttt ctgccattat agtggggact
    15721 tttaatcatc atttcaaaat gacagatggt ttcaaagcaa catttagtgg ttttaacgac
    15781 tcaatgatac atcagtctca tatttcatcc agtgtgaaaa gcttgttaga acagggtggt
    15841 atgatgagta tgacccaaat attagtaacg atattttgcg gatatgcatt tgcaggtatt
    15901 gtagaaaaag caggatgttt agaagtctta ttaactacta tttctaaagg catccattct
    15961 gtaggaagtt taatatgtat tactgttatt tgttgtattg cgcttgtatt cgctgcaggt
    16021 gttgcttcga ttgtaattat tatggtcggt gtgttaatga aagatttgtt cgaaaaatac
    16081 caagtctctc gttccgtttt atcaagaaca cttgaagact caagtacgat ggtcttacct
    16141 ttaataccat ggggaacatc aggtatttac tatacgaatc aacttcatgt ctctgttgga
    16201 gaatttttca tgtggacagt accatgttat ttatgcgcaa ttatagcaat tatctatggt
    16261 tttacaggga taggtattaa aaagtcatcg aattcacgtt taacttaatg tgagcgtgga
    16321 atatatataa tatgttgaaa cactttaatc atttataatt gtagcggtta taatttgaaa
    16381 aggttttaac ttagaataaa tatcctctat acatatactg aatatgtttt gtagcggaac
    16441 atgttgatat atgtaatgta agttttatgt catgatttgt aatgactaaa ttaattgaga
    16501 atttgaaggc aagtatattt gtaagtactt taactaaaaa tttatcaatg tatagccgat
    16561 ttgacatgcc taaatttggg tgtgtcaatg gctgtatgtt gtttattctt tattacagag
    16621 tgaatcggat tggtgaaaat cgaaattttg agatttttac caattcgatt tttttcatag
    16681 aaattaaaaa agccaacaag gctcttgaaa ccttgttggc gtaaaacata gccatcacta
    16741 attagtgaat gaagttataa ccagcagctt ggctagctga gattgtacgt gaagttacaa
    16801 cacctgggcc ataaccatag ttcatttctg aaactcttac tgaaccattg ctgttaacac
    16861 tttcaacgta tgcaacgtga ccgtatgcac cttgagttgt ttgcataatt gcaccagctt
    16921 ttggtgtatt gttcactgtg taaccagctc ttgcagctgc gttagcccag ttacttgcat
    16981 tgccccaagt tgaaccgatt ttaccaccta cacgatcaaa tacgtagtat gtacattgac
    17041 cagaagtgta taagttacgt cctgaagtat aaccacttga gattgaacgg ccatttgatg
    17101 atggagccat agttgtagtt acttgaacat tgttgcttga agtgctgtag cttgcaccta
    17161 aaccaccagt acggtagctg tttgtgttgt aactattata gttattgtag ttatatgatt
    17221 gattattatt tgagtagttg ttgtaacggc tgtaattatt gtagctataa ccattgttgt
    17281 aattgttgta gttattgtag ccattgtagt agtaatagct gtagtagcca ttatcttggt
    17341 ttaattgact tggatgccag ttacctttcc atgtgtaatg gtagttacct tgtgcatcaa
    17401 tagtgtaagt atagctatat gatgttgggt cgtttggatt ataaccgtag ttatcttgct
    17461 cagaagcatg agcttgattt cctgatgcaa ttgcgattgt agcgaatcct gcagttgcga
    17521 tagtagctgt agcgattttc ttcattttaa aaatatcctc ctaaaaattt taaatctaaa
    17581 atattttcgt aatgtccgtg tgacaaaatt aatgttataa gttatctctc gtaattaaac
    17641 gacaagaaag actataacag aaattagcgt ccttgtgtgc tttgttaacg ttttgtaatt
    17701 ttttgctaat atcttgacac aatagaattt taaaagtata gaaatttgca ttttgcaaaa
    17761 cttataacta cggcattctt tgtgaaaact gaatgtttcg aaaataagtc tgttacaaat
    17821 ttgtaatatt actgaaaatt ctaaatgtat attttgtgca taatatagga cttttaatca
    17881 gaaaatgcat aaaaactcga cacgaacgat caagtttcta tgattatgaa agctttggta
    17941 tttggatgaa aatatatatt taatggataa aatatcctaa tttagcataa aaaaatgttt
    18001 taataaaagt attatttgat ataatcgact tatgttttgt tactgctaaa aaacatgtgg
    18061 cgatataatt ggtagtgaat attagatgtt gacaattgat ttgagaaaga caaacaggag
    18121 taaatcaata tatttgtata tgtgaggatg taagatgaca gataattatt cactacatat
    18181 ttataaaagt atgaaaatga gtagtgtgaa ggaagcgaac ttaaaaatta tatattggct
    18241 acaaggtaca ggtgtagttt caatcaatct acaacaatat gatgtaaaaa gaaatgatgt
    18301 caccgttatt atgttgaatg atttgtatca aattgatggt catgatgata gtgtatgttg
    18361 tgttgttgaa gtaagtgcaa agacattttt gaagtttatg aatgcaaact atatgatgcg
    18421 tggcaagata ttaacaaatg aggttgctag cacttttaga atcttgatta agtatttaat
    18481 ctacagcaaa attaaacaac agtcttataa tgctaatgat aagattatta attacatgtg
    18541 tgttgaatta atgtcattaa atacatacga tggtagtcgt catttagtag ccgaagaagt
    18601 gcacgattat ttaacaaaca accaccataa aaagataaat aggaaagatg tcattaatca
    18661 agttagtatt acaaacaaag ctttaagtga catgtttaaa gcgacacctt atagtaattt
    18721 tattcaatat ttaaatcata ttagactgga gcattgctta attgatattt taacttctaa
    18781 gaagcctatt gaagaaatcg caagtagtca tggttttaat cattattctc gttttataca
    18841 cctctttaaa gaaacgtatg gtaacactcc taaattaatt agaaaaagat atagtccaac
    18901 atctcattca attaaccatt cccaattagt tgaaattgat aaaaatataa ttgaattatt
    18961 tgataatact aatcaaagtt cttcaagtat gcgcgagatt gatatacctt ttgaacctac
    19021 aaaaaggagt caaatgtatc aacctaaaaa catttatatt aaaggaagta atttttattg
    19081 gatggattat tatactatta aacaaatcat tcaaagatta ggtgttaatc ttgaaaactt
    19141 gcatataatt gttacaatcg acacaagcaa tgagctatcg attgaacaaa tcactttatt
    19201 acttcaaaag atagtgaatt acaatgtaaa tgtagtattt cgtattaaac atgaatataa
    19261 ggaattgtta acgagtactg aaagaggcaa gatagaaaag ctagtagcca caatttttaa
    19321 tatgacattt gagagtaata gatgtaagat tgcattttta attaacgact taaatactac
    19381 tgcaattcaa aaactgaaac gcttaataga taattatata ggagtatttg aattaatata
    19441 tcatctggaa ccaaaagagt tgaatacgca ctatgataaa gaaattgatc atctaataga
    19501 ctattttatc ttaccgctaa gacaaataga acaggtgtct attgcatgtt ctaaaattat
    19561 atgtgatgta gatttgatta atgagaataa tgacttaaaa gaaaaaatca caatgtctga
    19621 ttttaataag gttactgaac ttttgacaaa ttatacaaaa tttcgaggac ttattatgca
    19681 catgtcaatt ataagtgaag ctagcaaaga aataaatttg actagattat caatattcat
    19741 ttttatcata aatatactta atcaattacg agggattgtt atttatcaaa atgacacgat
    19801 gattgtaacg aagttcaaac atgaagtaca atgtgtcatt tgtttgccag ccgcattgtt
    19861 aaatgagaat tcagacgcta tacgtttatc gtgtaagggt cttcaacaat ttagccatgc
    19921 taaaactaaa caaattgttt taagtataga taaagataat catacttccg aaaatggtgt
    19981 acttgtgaat gatattatgc aacaacacag ttattggaaa gctaatttta tagaaagaaa
    20041 tatttatgat cattcattaa tggtctcaag caatagtatt gttcatttga aatatcatct
    20101 tgagatatag gcatggttta agagaggttt taaagatgtc taaatttaaa gttaagcgtt
    20161 taactgcaca catactaatg ttgaaagtca ttaatgatat gttgaaatat tcatttcatc
    20221 tcactttgac tcaagtgaaa ctattaaatc tattagttaa atatgataat tctgattcca
    20281 atagcgcttc aatagatagg ttattaaaaa tgaaagaaat ccaatctaag atggcacttc
    20341 ttcaaatgtt aagttattta aacaatcatc aatggctatt gaaaggaaga gatcaaaggg
    20401 atcaacgtaa attgactatt tcgattaata aaatgcatat agataaaata gaatatatga
    20461 ataatgagct tagtgactat attgaacgtt attttggtca atatacattt gattttagtt
    20521 gtgactatgt atcgtattta ttgtcgtcac aagaattatt tcgaaatcta aagtgttatt
    20581 taaatatgtg tcaattaaca ttagaagagt tatacgtttt aggaatatta aatctgcata
    20641 aaggtcaatt gatggttaaa gaattacagg gtgaattcca tcacccgata tttgcggtta
    20701 gcccgatttt aaagtgttta attttgaagg gattagttaa aaaagagaga tgtgaattag
    20761 atgaaagacg tgttattgta acaatcaagc gagaaaagtt ttctaaagtc actatgctta
    20821 ttcaagcatg ttataattat cttgaaaagg gaatacaagt taagcttaat aataaatagt
    20881 taatcacttg tatttcatat acctatgaag aatagtttat agttttaagt gggagggata
    20941 ttatgatttt agataatgtg aatccgaatg atttatttcc aactgaaaaa aagggtccgt
    21001 cagtgctagg aataattgag tatcaagttc aaggtgagaa tgaatttgaa ggggcattta
    21061 tagcaacaaa tgaaagatta attatgaatg tagatatgaa tggccaattt tattatagaa
    21121 gtattagtta taatgaaata gagaagatag attatgatgg tcaaactata atgttcaaat
    21181 ttaatattgg taatgtccca atgcatgata ttaaaagtga taacgttgaa atgtttgttg
    21241 aatatgtaaa acaacatatg atagtataat gtcaatgtat gtaggttgat aagaagagtt
    21301 tgaatgataa ctcattgcat ttaaagataa atggcatgcg ttatgattta aagctcttct
    21361 ttttttatat tttataaatt ttgtgagcaa gccatccaat taatataaaa aatatcaaat
    21421 caaacacgtt gatatagatt aaaattttaa aagtttacat atcagttaag atacaaaata
    21481 ttcagactaa taattttcaa tttggcaaaa tatcttaaac atcaaattat tataagaaat
    21541 aaatgtattt aaccatattc tagtaataaa aatattgaat ttttatactt atttgtttag
    21601 aatgaacttt ataacatagt tggatagagt ttcgatttaa taaattacat gtgaaccttg
    21661 ctacaacaag atgtgcatca gaggagtggt ttaataatga gtaaaattaa tgacattaat
    21721 gatttagtca acgcaacatt tcaagttaag aagtttttca gagatacaaa aaagaagttc
    21781 aatttgaact atgaagaaat ttatatttta aatcatattt taagaagtga gtctaacgaa
    21841 atctcatcta aagagattgc taagtgctca gagttcaaac cttactattt aactaaagct
    21901 ttacaaaagc taaaagattt aaaattgtta tcaaagaaaa gaagtttaca agacgaaaga
    21961 acagttattg tttatgttac agatacacaa aaagcaaata ttcaaaaact gatttcagaa
    22021 ttagaagaat acattaaaaa ttaaatcaag gttaattgcg tttaataaca ttgaacgata
    22081 acaatttatt aaaacgaagt tatttattca gcattgggac ataaaattaa cttaaaattt
    22141 aaatattgaa gatgctttaa ttaaagttaa agactagcca taccttattt cagcttatta
    22201 agcttgaaac aaggtacact agtcttttta ttttaatatt ttcttagaaa atcaagttta
    22261 cgatcataaa tattttctgc gatatagctt tggatggttc caagtatttt ctctataatt
    22321 tgtgtgcgat aagcaaaaat tctaactgca aagccatgtg taggcaattg agaaatagca
    22381 acacgacaat cgaatgtatt gctataagaa ctaatggttt cataaactga atcgattagt
    22441 ttttggttaa catcttcatg tatgaagtaa gcagagccat aatgagagta atgttccata
    22501 taacctattt cattgatcga ttgtttatta ggattcaata ataaattatc atatgtgact
    22561 aactcatctt caatataaat ttcatttatt aaatgcatat attgatactt gaaggcttcg
    22621 ccagtttttg aataaccagg agttaaaata tcagtataaa ataatgaact agaattattg
    22681 agattgaacg tattgtgttg ataaaattta gcattttcat atgcgatgat tggatcagcg
    22741 acatattcta aatatgcgtt atcttttaaa ttaaaagttt gatactgctc aacatgattg
    22801 gaaggtgtct tgtatatttt tgttgcacct tgagatgtca atgtcacttt agcgttatct
    22861 tcgacattca cattcatacg gtaacgatct ccatctaaat agccaccacc tacatttact
    22921 atataaaatg taggaatggt agattgattt agataaactg gacgtatcac tttaagtgct
    22981 ttttcaaaga aaatatctct tgatactgat cgattgccat cgaaaaacac tgttaaatca
    23041 agttgcccag tccattgttg ttcatccatt atgataatcc tttgagtaaa gtgtcgcgtt
    23101 caatccaatc gataacttca tccaaacctt cgtcggtttt taagttagta aaagtaaatg
    23161 gacgtttacc acgaaatact ttagtatctt cagccatttg ttctaatgat gcacctacat
    23221 agggagctaa atcagttttg ttaattacaa agaaatctga cttaatcata ccttgaccac
    23281 ctttacgtgg aatcttttca ccttgagcaa catcgataat atatattgaa aagtcaacaa
    23341 gttctgggct aaatgttgct gctaagttat cgccaccaga ttctatgaaa attagttcta
    23401 tatcgtcatg acgttctaat aattcgtcta ttgctgcaaa gttcatagat gcatcttcac
    23461 gaatcgcagt atgaggacat ccaccagttt caacaccaat gatacgactt tcaggtagaa
    23521 ctcctgaatt tactaatatc ttttcgtctt cttttgtata tatatcattt gtaataacgc
    23581 cgatactcat ttcttttgaa agacgtttta caactttttc aattaattgt gttttacctg
    23641 cacctacagg accaccaata ccaattttaa tcggatttgc cacaattata acctcctatg
    23701 atatgaaaat tctaacattg acgttctcat gcgccatttg atttagttct aaaccaggcg
    23761 ctgtcatgcc aaaatctgct tcttttaatt cgaaaatctg ctttcttgtt tcttctatat
    23821 aaggaatcat gtgagtaact atcttttgac cagcagtttg tccaagtgga atagcacgaa
    23881 cagcattttg agttaaactt gaaacatttt gatataaata gtaatcaata atcgtttcaa
    23941 tatctacacc taaatgatgg cctagcatag taaaacaaat agctggattt aactttgctt
    24001 tcttatcttg catttgttga tgataccaag caatccatgg gctattataa agttctaaag
    24061 ccaatttaac catgcgagtc cccatttgtt ttgcaccaac acgtgtttct ttaggtaagt
    24121 tttgaacaaa catcagttta tctatgtgta atactttttg tgtatcatca ttttccaatg
    24181 catcataaac taaacgcatg gctaaaccat cagaataggt aagttgctct tgtaaaaaca
    24241 tttttaacca agcaataaaa gtatgatcgt catgaattat atttcgttga atatatgttt
    24301 caagaccaaa tgaatgactg aaagcacctg ttggaaactg tgaatcacag aactgaaata
    24361 atcttaagtg tgtatgatca atcatgagaa tgccctatat gtctgaaagc cttattaact
    24421 ttacggtctt ctcgaacata tgggatgcct aaacttttta ataaatcttc aactaaataa
    24481 tcatattgta ctagcatttc agtctctgta aattgtgctg gcaaatgacg atttcctaat
    24541 tgatgggcta tatctcccat ttcttgcaat gttcttggtt gaatcactaa aagatcttct
    24601 gaattaacat ccacaataat catattatgg tcatctgcgt ataaaatatc tccatattgt
    24661 aagtcaatag gttgttttaa acgaatgcct atttcagtgc catggtctgt aacgactctt
    24721 tgaatacgtt taacaagatc tgaattttca aggtatactt tttcgacgtg cttttgtttt
    24781 tctgaatttg acaaattggc aatattgcct tggatttctt caacaatcat tctatgttcc
    24841 tcctagaata agaagtatct ttgagttaat ggtaactcag ttgctgcatt acttgtaatt
    24901 ttttctccat ctacatatac ttcatatgtt tgtggatcaa cgtctaattt aggtgttgca
    24961 ctgttatttt tcatatctgc tttagataat tgtctaatat ttttaactgg acgcaccatg
    25021 cgttttaaat ttaatgcacg attgatacca ttttcataag cagttttaga cacgaatgtc
    25081 attgacgtac ttgtaaggtt tccgccgtat tgaccataca ttttacggta cttcatcggt
    25141 tcagatgtag gtatagaacc atttgcatcg ccatttacgg cagagttaat taatccgccc
    25201 tttacaacta attcaggttt aaccccaaag aaaattgggt cccataagac aatgtcagct
    25261 agtttgcccg gctcgataga tcctacatat tcagaaatac catgtgtaat tgctgggtta
    25321 attgtatatt tagcgatata acgtttgatg cgattattat cattatgttc aaaatcacca
    25381 tctaaaggac cacgttgttc tttcatgcga tgtgctactt gccatgttcg tgtaattact
    25441 tcacctacac ggcccattgc ttgtgaatcg gaactaatca tactgaatac acccatatct
    25501 tgcagaacat cttctgctgc aatcgtttct ttacgaatac gtgaatctgc gaatgcgata
    25561 tcttcaggaa tagccgcatt taaatggtga gtaatcatta ccatatctaa atgttcatct
    25621 acagtattat gtgtataagg caaagttgga tttgtagatg aaggtaaaat atttgaaaat
    25681 gcagcggatt taattaaatc aggcgcatga ccgccaccag caccttcagt atggtacata
    25741 tgaagtacac ggtctttaac agcagccatt gtgtcttcca taaatcctgc ttcatttaaa
    25801 gtatctgcat gtaatgcaat ttgaacatca aattcatcag caacatctaa tgcatgactc
    25861 aaagcagatg gtgttgcacc ccagtcttca tgtactttta atccaattgc tccggcattg
    25921 atttgttcaa tgagtgcagt tggatttgtt gcttgtcctt tacctgtaaa accgacatta
    25981 atcggtaaac cttcggcagc ttctaacatt ctatgaatat gccatggacc tggagttaca
    26041 gttgttgctt tagaaccttc tgaagcacca gtaccaccac caatatgagt cgtaatacca
    26101 ctttctaatg cgacctctgc ttgttcagga ttaataaaat gaacatgagt atcaatacca
    26161 ccagcagtga cgattttacc ttcagcggca atgatatctg ttgttgaacc tataataatg
    26221 tcgacattat ccattatatc tgggttgccg gcattaccta tggcgaaaat ataaccattt
    26281 ttaatgccta tatcagcttt aaccacttta tcgtaatcga taataacggc attagaaatg
    26341 acaaggtctg caacgttcac gtcatcacgt gttacacgag gattttgcgc cataccgtct
    26401 ctaatagatt taccaccacc aaaagtagct tcttcaccat aaaccgcata gtctttttct
    26461 atttgagcaa atagattcgt atcacctaaa cgaatagaat ctccaacagt tggaccgtat
    26521 aagctcgtat attgattttg cgtcatttta aagctcatga tctttttcct ccttttttat
    26581 tcacgttttc agcaccgtta tctccgaata cacctgcata tgcatcattt tcatcagttg
    26641 ggcgatagac acgtgactca tcgataggac cattgaccat accacgaaaa ccaaaaattt
    26701 tacgtttgcc agcatattca actaattgaa cttctttttt atccccaggt tcaaatcgaa
    26761 cagctgctcc agctggaata tctaaatgtt ttccatatgc catttcacgt tcgaaatcta
    26821 atgctgcatt tgcttcataa aaatgaaaat gtgagcccac ttgaattggt cgatctcctg
    26881 tattttcaac ttcgataact gtttcaggat gatggttatt aatttcaacc tctgtacttt
    26941 ttgtaataat ttctcctggt atcatttgac tgcctccttt aaacaatagg gtgatgtact
    27001 gtgattaact tagtaccttc ggggaacgta gcctcgattt cgatatctgt aatcatgtgt
    27061 tcgacaccat ccatgacatc ttctttgttt agaatttgtc taccataact cattaactct
    27121 gcaacggtct taccatcgcg tgcaccttct aataattcat cgctgattaa agctaatgcc
    27181 tcaggatgat ttagtttcaa accacgtgct ttacgacgac gtgcaacttc cgccgccact
    27241 acaatcatta atttgtcttg ctctcgttgt gtaaaatgca aattaaaacc cccaatttca
    27301 tattagatac aatttacaaa atttatatta atcctaattg ttgtgataaa caagtaatat
    27361 acaaagttca atgtgtaatt agaaaattat atttttagca tatccgctat tgaagcaaac
    27421 aatctaatcg aaaacaaata gcggaatata tttatgtaaa aaccaaaata gtttttaata
    27481 taacttttca tagaatagta gtatattaat gagtaatgat tcaaaggaaa ggtgaaagat
    27541 ttgaagataa tagatgtgct tttgaaaaat atatctcagg ttgtgttaat tagtaataaa
    27601 tggacaggat tatttatctt aataggatta tttgtagccg attggacaat tggattagcg
    27661 gctattgtag gtagcatcat cgcctatact tttgcgcgtt ttataaatta tagtgaggca
    27721 gaggttaatg atgggttagc cggatttaat ccagtgttaa ctgccattgc gttaacaatc
    27781 tttttagata agtcaggatt agatattgtt ataacaatga tagcaacttt attaacgtta
    27841 ccagttgctg ctgcagtgag agaagtttta agaccatata aagttccgat gctgacgatg
    27901 ccttttgtca ttgtgacttg gtttacaatt ttactttcag gacaggttaa atttgtagat
    27961 acatcgttaa agttaatgcc tcaaaacatt gaaacggtta attttagcaa caatgataga
    28021 atacatttca ttcagtcatt atttgaagga ttcagtcaag tatttatcga agcgagtgta
    28081 attggtggcg tatgtatttt aatcggcata ttgatagcat caagaaaagc agcactctta
    28141 gctgttatag ctagtttgtt aagctttatc attgtagctc tattaggtgg taattatgat
    28201 gatattaatc agggattatt cggttataac tttgtattaa tggcaatcgc actaggatat
    28261 acatttaaaa cagcgattaa cccttatatt tcgacttttt taggtgtgtt attaacagta
    28321 gtggtgcaac taggtacaac aacattgctt gaaccgtttg gcttacctgc attaacattg
    28381 ccatttatta tcgtgacatg gattttatta tttgctggta ttaaacatga caaagtagat
    28441 gcttgatagt taaatcaaac ctaatattgt ttgaatatca ccttaaacca tacagcgaat
    28501 tgtatagttt aaggtgtatt tttatggata aaattaagtg catacttaat cgaattatca
    28561 gttttctttt aattgttcac agcacgttcc tttttatttt taaagtcgag tgttaaacta
    28621 ggaataaata atttatattg tgtgttgtgt ggggtgacta atatgaatga tatggataat
    28681 tcctttttaa taacaacgga aattcaaaga aaatggattg aaaaattcaa agtaattaga
    28741 gatacattta aggctaaagc tgaatataat gatcaacata gccaatttcc atataaaaat
    28801 attgaatggt taattaaaga aggttatgga aaattaacgt taccaaaagc atatggtggt
    28861 gaaggtgcga ccatagaaga catggttatt ttgcaatcat ttttaggcga acttgatggt
    28921 gccacagcat tatctattgg ttggcatgtg agtgtcgtag gacaaattta tgaacagaaa
    28981 ttatggtctc aagatatgtt ggagcaattt gctgttgaaa ttaataatgg tgcattagtt
    29041 aatagagcag ttagtgaagc tgaaatgggt agtccaacaa gagggggaag accaagtaca
    29101 catgctgtta aagctgatga tgggtatatt ttaaatggtg tgaagacata tacatcaatg
    29161 agtaaagcac taacacatat tattgttgct gcttatatag aagaattaga aagtgttggt
    29221 tttttcttag tagacaggaa tttgcctggt gttgaaattg ccgataattg ggacgtatta
    29281 ggtatgcgag cgacagaaag tcatgattta atattaaatg atgtaaaagt accattaaaa
    29341 catttagtgg aaacagagaa aagtaaagcg ccaaatggtt ggatattgca tataccaagc
    29401 tgttatttag gtatagcaca agctgctaga aattatgctg tagactttgc aatccaacat
    29461 agccctaata gtattgaagg aacgattgca acattgccaa ctgtgcaaca aaatttaggg
    29521 aaaatggaaa cgctattgtt atgtgcgaga caatttttat ggagtacagc aaaagggtat
    29581 caacaatata aagatgacag tcagataaga aatccaacaa gtgcgagtaa agtgatggta
    29641 atgaatcaag ggcttgaagt gattgattta gcgatgagaa tagttggtgc taaaagctta
    29701 gaaatgaatc gaccattaca acgttactat cgtgacatgc gtgcaggatt acacaatcca
    29761 cctatggaag atgcagcata tacaaatatt gctaagagta ttacagatac attttaaatt
    29821 taaaaaggta aatcgatcgt tgattggcat aaagagatga aatttgacgt tcggatttac
    29881 ccttttttgt ggggatttat agggatgtta agatatt
//
LOCUS       DAPDIM010000034        29714 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000034 DAPDIM010000000
VERSION     DAPDIM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 29714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29714
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.034"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(125..343)
                     /locus_tag="RFE25_001538"
     CDS             complement(125..343)
                     /locus_tag="RFE25_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816598.1"
                     /translation="MSEWHINNQSTKPFLIQQAEKQLSIVKPLPNGSFQILTEINLEN
                     GNISNIDHSLLVSVDPKALEISIFDAVN"
     gene            complement(405..689)
                     /locus_tag="RFE25_001539"
     CDS             complement(405..689)
                     /locus_tag="RFE25_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816599.1"
                     /translation="MNELTKEQKYTIAKFYKLYIERSNNGETETVANFFGDAKDAREN
                     YFCDRDYQDFLTNCQILIQNKYLTGEILDDNIYNISILNKTFIEFEQNFG"
     gene            complement(777..1346)
                     /locus_tag="RFE25_001540"
     CDS             complement(777..1346)
                     /locus_tag="RFE25_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816600.1"
                     /translation="MNYIKRTIILLILFVVVSPINSPKTIADNKYSEIQDDKFQLQPG
                     DIIVTKGPVMWGFFGHCSIAIDDKTILQIEGPGDKPTTQSFESFKYNYASGKNDWMKV
                     YRCSYPGAGKKAAEWVKKNYENTNHRYLVTLNLNSKKFTYCTKIIYQAYKFGVSEKSV
                     KSYGLHIISPYAIKDNFIDPYKLRLVKAY"
     gene            complement(1534..1722)
                     /locus_tag="RFE25_001541"
     CDS             complement(1534..1722)
                     /locus_tag="RFE25_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816601.1"
                     /translation="MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVI
                     LYIFGFAILIYTFIFGVL"
     gene            complement(1751..2011)
                     /locus_tag="RFE25_001542"
     CDS             complement(1751..2011)
                     /locus_tag="RFE25_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816602.1"
                     /translation="MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICG
                     VILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPIFYSFIG"
     gene            2352..2555
                     /locus_tag="RFE25_001543"
     CDS             2352..2555
                     /locus_tag="RFE25_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterile alpha motif-like domain-containing
                     protein"
                     /protein_id="HDU2816603.1"
                     /translation="MTFYNFIMGFQNDNTPFGILAEHVSEDKAFPRLEERHQVIRAYV
                     MSNYTDHQLIETTNRAISLYMAN"
     gene            complement(2552..2788)
                     /locus_tag="RFE25_001544"
     CDS             complement(2552..2788)
                     /locus_tag="RFE25_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816604.1"
                     /translation="MDHHNQCNYVNPQNVSLDWECFIISKSEMLLDGVPNELINTWLD
                     KDIITPFSIRNDEINFKTKDIWDALIHHNWYYSN"
     gene            3013..3594
                     /locus_tag="RFE25_001545"
     CDS             3013..3594
                     /locus_tag="RFE25_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDU2816605.1"
                     /translation="MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYY
                     ETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYK
                     PEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKL
                     DEALKHNIGNCNILKFEYDNGTFKFVELIDPNL"
     gene            complement(3667..4284)
                     /locus_tag="RFE25_001546"
     CDS             complement(3667..4284)
                     /locus_tag="RFE25_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid transporter"
                     /protein_id="HDU2816606.1"
                     /translation="MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAII
                     TAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQ
                     IISPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFL
                     LAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF"
     gene            complement(4439..4933)
                     /locus_tag="RFE25_001547"
     CDS             complement(4439..4933)
                     /locus_tag="RFE25_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2816607.1"
                     /translation="MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDI
                     LNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINF
                     IINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYD
                     LINK"
     gene            complement(5332..5754)
                     /locus_tag="RFE25_001548"
     CDS             complement(5332..5754)
                     /locus_tag="RFE25_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDU2816608.1"
                     /translation="MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPE
                     QLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKN
                     VISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD"
     gene            5902..6618
                     /locus_tag="RFE25_001549"
     CDS             5902..6618
                     /locus_tag="RFE25_001549"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDU2816609.1"
                     /translation="MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENV
                     TVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMID
                     IEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVK
                     LAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIG
                     EPQAPGQIDVTDLKAQVTLY"
     gene            6701..7240
                     /locus_tag="RFE25_001550"
     CDS             6701..7240
                     /locus_tag="RFE25_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDU2816610.1"
                     /translation="MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMRE
                     PWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQN
                     DENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTD
                     LEEDMPKAPRKNRNLITLY"
     gene            complement(7391..7711)
                     /locus_tag="RFE25_001551"
     CDS             complement(7391..7711)
                     /locus_tag="RFE25_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDU2816611.1"
                     /translation="MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVE
                     QYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLA
                     ETFK"
     gene            7855..8211
                     /locus_tag="RFE25_001552"
     CDS             7855..8211
                     /locus_tag="RFE25_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDU2816612.1"
                     /translation="MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKT
                     IIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDK
                     ITLGFKEGQYKETWLA"
     gene            8369..8749
                     /gene="gcvH"
                     /locus_tag="RFE25_001553"
     CDS             8369..8749
                     /gene="gcvH"
                     /locus_tag="RFE25_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDU2816613.1"
                     /translation="MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELP
                     ETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVK
                     VEISDESQLEALLTAEKYSEMIGE"
     gene            8928..9806
                     /locus_tag="RFE25_001554"
     CDS             8928..9806
                     /locus_tag="RFE25_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1963 domain-containing protein"
                     /protein_id="HDU2816614.1"
                     /translation="MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQ
                     EETLSQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFW
                     ISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQVHLKSLDADNEDIPFSGAF
                     SIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEP
                     FNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTD
                     LEAMKFDDYMYSWDCS"
     gene            10602..10988
                     /locus_tag="RFE25_001555"
     CDS             10602..10988
                     /locus_tag="RFE25_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDU2816615.1"
                     /translation="MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDM
                     IESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLS
                     KHGFTCKKETPLLPNINNERLVLVNE"
     gene            10981..11277
                     /locus_tag="RFE25_001556"
     CDS             10981..11277
                     /locus_tag="RFE25_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDU2816616.1"
                     /translation="MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEI
                     LQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK"
     regulatory      11335..11438
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            11527..12552
                     /locus_tag="RFE25_001557"
     CDS             11527..12552
                     /locus_tag="RFE25_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDU2816617.1"
                     /translation="MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGK
                     STLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKN
                     IMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPT
                     VLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGK
                     VIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTT
                     EPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVK
                     MEVLRHG"
     gene            12545..13240
                     /locus_tag="RFE25_001558"
     CDS             12545..13240
                     /locus_tag="RFE25_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2816618.1"
                     /translation="MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFIL
                     GLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISG
                     PTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPAL
                     VSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQ
                     FIGDWLTNKLDKR"
     gene            13258..14079
                     /locus_tag="RFE25_001559"
     CDS             13258..14079
                     /locus_tag="RFE25_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDU2816619.1"
                     /translation="MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAE
                     ILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKI
                     VSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGV
                     KIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDS
                     IAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK"
     gene            14433..14627
                     /locus_tag="RFE25_001560"
     CDS             14433..14627
                     /locus_tag="RFE25_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDU2816620.1"
                     /translation="MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFV
                     ENAKEKATDFIDKVKGNKGE"
     gene            complement(14861..15712)
                     /locus_tag="RFE25_001561"
     CDS             complement(14861..15712)
                     /locus_tag="RFE25_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HDU2816621.1"
                     /translation="MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASIS
                     GIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYL
                     LKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMC
                     ASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISS
                     KIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLG
                     RITAENE"
     gene            16040..16801
                     /gene="sufC"
                     /locus_tag="RFE25_001562"
     CDS             16040..16801
                     /gene="sufC"
                     /locus_tag="RFE25_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDU2816622.1"
                     /translation="MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKS
                     TLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFM
                     RSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQL
                     MMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVH
                     VMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE"
     gene            16899..18206
                     /gene="sufD"
                     /locus_tag="RFE25_001563"
     CDS             16899..18206
                     /gene="sufD"
                     /locus_tag="RFE25_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDU2816623.1"
                     /translation="MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPK
                     PDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQ
                     VDDNASKDGVIVEGLADALMNHSDLVQKHFMKDAVTVDEHRITALHTALVNGGVFVYV
                     PKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIIS
                     EVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNL
                     FGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYI
                     KHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMS
                     RGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK"
     gene            18312..19562
                     /locus_tag="RFE25_001564"
     CDS             18312..19562
                     /locus_tag="RFE25_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDU2816624.1"
                     /translation="MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQ
                     VLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTA
                     SINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNI
                     EDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDM
                     QEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLP
                     TKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPP
                     KDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIY
                     NTKEDIDQLINALKQTKEFFSYEF"
     gene            19552..20016
                     /locus_tag="RFE25_001565"
     CDS             19552..20016
                     /locus_tag="RFE25_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HDU2816625.1"
                     /translation="MNFNNLDQLYRSVIMDHYKNPRNKGVLDNGSMTVDMNNPTCGDR
                     IRLTFDIEDGIIKDAKFEGEGCSISMASASMMTQAVKGHSLGEAMQMSQEFTKMMLGE
                     DYVITEEMGDIEALQGVSQFPARIKCATLAWKALEKGTVAKEGKAEGTTEEE"
     gene            20167..21564
                     /gene="sufB"
                     /locus_tag="RFE25_001566"
     CDS             20167..21564
                     /gene="sufB"
                     /locus_tag="RFE25_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDU2816626.1"
                     /translation="MAKKAPDVGDYKYGFHDDDVSIFRSERGLTENIVREISNMKNEP
                     EWMLDFRLKSLKLFYKMPMPQWGGDLSELNFDDITYYVKPSEQAERSWDEVPEEIKRT
                     FDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEEKGIIFKDTDSALQENEELFKKY
                     FASVVPAADNKFAALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLII
                     ADEGASVHYVEGCTAPVYTTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRT
                     FVYENGNMEWVDGNLGSKLTMKYPNCVLLGEGAKGSTLSIAFAGKGQVQDAGAKMIHK
                     APNTSSTIVSKSISKNGGKVIYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYN
                     EVFNDQISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAV
                     EMNRLIKFEMEGSIG"
     gene            21751..21890
                     /locus_tag="RFE25_001567"
                     /pseudo
     CDS             21751..21890
                     /locus_tag="RFE25_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21896..22210)
                     /locus_tag="RFE25_001568"
     CDS             complement(21896..22210)
                     /locus_tag="RFE25_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816627.1"
                     /translation="MYFVLAIFTIISASVSLGYSIQACASSHNINAYYALSRSLPLFL
                     LAIFSLVIHSAIFLITISIAMILVQFLDAIVGYKSEDVFKTYGPLATSVVNLILLIVF
                     LF"
     gene            22575..23615
                     /locus_tag="RFE25_001569"
     CDS             22575..23615
                     /locus_tag="RFE25_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDU2816628.1"
                     /translation="MIIAIIILIFISFFFSGSETALTAANKTKFKTEADKGDKKAKGI
                     VKLLEKPSEFITTILIGNNVANILLPTLVTIMALRWGISVGIASAVLTVVIILISEVI
                     PKSVAATFPDKITRLVYPIINICVIVFRPITLLLNKLTDSINRSLSKGQPQEHQFSKE
                     EFKTMLAIAGHEGALNEIETSRLEGVINFENLKVKDVDTTPRINVTAFASNATYEEVY
                     ETVMNKPYTRYPVYEGDIDNIIGVFHSKYLLAWSNKKEDQITNYSAKPLFVNEHNKAE
                     WVLRKMTISRKHLAIVLDEFGGTEAIVSHEDLIEELLGMEIEDEMDKKEKEKLSQQQI
                     QFQQRKNRNVSI"
     gene            23629..24696
                     /locus_tag="RFE25_001570"
     CDS             23629..24696
                     /locus_tag="RFE25_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDU2816629.1"
                     /translation="MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIG
                     AGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLE
                     EPVVKIIEEQQFKCHIDTIIKKQVPVCCFTFGIPNESIIERLKEANIKLIGTATSVDE
                     AIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGG
                     IMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVVTKAFSGKL
                     ARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELTHMWSGQSPRLATT
                     HPANTIMSNIINQINQIMQYK"
     gene            24950..25033
                     /locus_tag="RFE25_001571"
     CDS             24950..25033
                     /locus_tag="RFE25_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816630.1"
                     /translation="MIIIKRKHQAEDRRKILIKRKHQIKVR"
     gene            25081..25929
                     /locus_tag="RFE25_001572"
     CDS             25081..25929
                     /locus_tag="RFE25_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDU2816631.1"
                     /translation="MINIGLTGWGDHYSLYEDLERQTDKLKTYAGHFPVVELDATYYA
                     IQPERNILKWIKETPDTFEFVVKIHQALTLHADYKTFADTRQELFDQFKNMLEPLHTQ
                     KKLAMVLVQFPPWFDCNAQNIKYILYVRQQLQAFPMCVEFRHQSWFSDAFKEQTLAFL
                     TEHQIIHAVVDEPQVKDGSVPLVNRITNEIAFVRYHGRNHYGWTKKDMSDQEWRDVRY
                     LYDYNEQELIDLAQKAQILAQKAKKVYVIFNNNSGGHAANNAKTYQRLLNIEYEGLAP
                     QQLKLF"
     gene            25942..26769
                     /locus_tag="RFE25_001573"
     CDS             25942..26769
                     /locus_tag="RFE25_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDU2816632.1"
                     /translation="MLLTITLLVLIGGLSAIIGSIVGIGGGIIIVPTMVYLGVEHGLL
                     HNITTQVAIGTSSVILIVTGLSSSLGYLKTKQVDIKNGSIFLFGLLPGSLLGSFISRY
                     LTFESFNLYFGIFLIFVAILLMVRNKIKPFKIFDKPKYEKTYVDAKGKTYHYSVPPLF
                     AFITTFLIGILTGLFGIGGGALMTPLMLIVFRFPPHVAVGTSMMMIFFSSVMSSIGHI
                     AQGHVAWGYAIILIISSYFGAKIGVKVNQSIKSDTVVTLLRTVMLLMGIYLIIRALI"
     gene            26796..28115
                     /locus_tag="RFE25_001574"
     CDS             26796..28115
                     /locus_tag="RFE25_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDU2816633.1"
                     /translation="MRLTIYHTNDIHSHLHEYERIKVYMAEQRPRLNHPSLYVDLGDH
                     VDLSAPITEATLGKKNVALLNEAKCDVATIGNNEGMTISHEALNHLYDEAKFIVTCSN
                     VIDESGHLPNNIVSSYIKDMDGVKILFVAATAPFTPFYRALDWIVTDPLESIKEEIKH
                     QRGKFDVIIVLSHCGIFFDETLCQELPEIDVIFGSHTHHYFEHGEINNGVLMAAAGKY
                     GNYLGEVNLTFEAHKVVHKTAKIIPLETLPEVETSFEEEGKTLMSNSVIQHPVVLKRS
                     MNHITEAAYLLAQSVCEYTHAQCAIINAGLLVKDIVKDEVTEYDIHQMLPHPINMVRV
                     RLSGVKLKEIITKSNKQEYMYEHAQGLGFRGNIFGGYILYNLGYIHSTGRYYLNGEEI
                     EDDKEYVLGTIDMYTFGRYFPTLKELPKEYLMPEFLRDIFKEKLLEY"
     gene            28199..29116
                     /gene="lipA"
                     /locus_tag="RFE25_001575"
     CDS             28199..29116
                     /gene="lipA"
                     /locus_tag="RFE25_001575"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HDU2816634.1"
                     /translation="MATKNEEILRKPDWLKIKLNTNENYTGLKKMMREKNLNTVCEEA
                     KCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNL
                     KHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASR
                     PDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEI
                     YETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGP
                     LVRSSYHADEQVNEAAKEKQRQGEAQLNS"
     gene            29246..29629
                     /locus_tag="RFE25_001576"
     CDS             29246..29629
                     /locus_tag="RFE25_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HDU2816635.1"
                     /translation="MIKVDQHYFELIENYRECFNEEQFIARYSDILDKYDYIVGDYGY
                     DQLRLKGFYKDSNKKAEMSKRFSNIQDYIFEYCNFGCPYFVLRHLSKQEVKKLIEEVH
                     PSDVIDDDNKLQDVKIKPTIQDTEH"
BASE COUNT        10733 a         4205 c         5312 g         9464 t
ORIGIN      
        1 attttttatt aagactgatt aattattgag aatatttatt gtttttaaaa tctcataata
       61 attcagtaat cttgttttca tttaaaaggc gaaacattaa aataattaaa taaaaatatt
      121 gcgtttaatt tacagcgtca aatatactta tttctaatgc tttggggtct actgaaacaa
      181 gtaaagaatg atcgatgtta ctaatattgc cattctccaa atttatttct gtgagtattt
      241 ggaagctacc attaggcaat ggtttaacaa tagacaattg cttttccgct tgttgtatta
      301 aaaaaggttt tgtagattga ttattaatat gccattcact catgtatgtt tttcactcct
      361 gctttaaaat agggttaaaa agtttatagt tgagacattc atgttcaacc aaaattttgt
      421 tcaaattcaa taaatgtctt gtttaaaata gaaatattgt aaatgttatc gtccaaaatt
      481 tcaccagtta agtatttgtt ttgaattaaa atttggcagt tagttaagaa gtcttgataa
      541 tcacgatcgc aaaaatagtt ttcacgtgca tctttagcat cgccaaaaaa gttagcgact
      601 gtttctgttt ctccattatt cgaacgttca atatataatt tgtaaaattt agctattgta
      661 tacttttgtt ctttagttag ttcattcaaa atattgggcc tcctgaaata tcatttgtaa
      721 tctataccca atttattgca aaacacaaac taatttaact atttgatgaa actgtgttaa
      781 taagctttta caagccttag tttgtatgga tctataaaat tatctttaat tgcatagggt
      841 gaaataatat gtagtccata acttttaact gatttttcac ttacaccaaa tttataagct
      901 tggtagataa ttttagtaca atacgtaaat tttttgctgt tcaaatttaa tgtaactaga
      961 taacgatgat ttgtattttc atagtttttc ttaacccatt cagccgcttt tttacctgca
     1021 ccaggatagc tgcaacgata aactttcatc caatcatttt tgccacttgc ataattatat
     1081 ttaaaagatt cgaaggattg tgtagttggt ttgtcgccag gcccctcaat ttgtaaaatc
     1141 gttttatcat caatcgcgat actacaatga ccaaaaaatc cccacatgac agggcctttt
     1201 gtaacaataa tatcaccagg ttgtaattgg aatttgtcat cttgaatttc tgaatactta
     1261 ttatctgcaa ttgtttttgg tgagtttata ggggatacga caacgaataa tataagtaaa
     1321 attatcgttc gtttaatata gttcacttaa aagctccttg ttgaagaaat atatgtaaat
     1381 agtcttaaat tagaattgta atctttaata agcttgtaag actaaaacat atcttaaata
     1441 ttaaagtatg agagtgtgaa atgtctatta agaataaaaa acagtctgaa acatcattga
     1501 gacgtttcag actggatata aaatgaattt catttatagc acaccaaata taaatgtgta
     1561 tattaatata gcgaatccaa aaatatagag aatgacagtg aaacttaaat aggactcttt
     1621 tttagattct ttgccagttt ttttcattaa tacgagtata aacgtagcgg caactaagaa
     1681 aattaatgct agccaaaaca gaattgcaaa atgtaaagac atgtgaaacc ctccttatat
     1741 accgtaatta ttaacctata aaactataaa aaataggata aatgtaatag agaacgagta
     1801 cgatatttat aaaaaataat atttcactta accagttttt agttatcatt gcaatggtaa
     1861 aggatacgat gagtatcaca ccacaaatga taataccagg caggagccaa cataaatcat
     1921 ctaaatcttt attatatgtg attaaaatat taaagataac aaaagtggta gtaataacta
     1981 tattgatagc atttaacaaa atgttattca tgactgacac ctactagtat aaaaatagct
     2041 tcttaataaa tatgataaca ctattttcca ataggtaaat aaaaagtata gttattttta
     2101 aaatattatt tgtagaatgc taaagtttat taattcaaac aagtgagcat atatagggat
     2161 gtatagtatt aatatgaaaa gaatatttac atactaaaaa ctcttaaagt tgtataattc
     2221 gttaatattt ttagaatcag atatcaaaaa aatgtgcaaa atcacttttg cacatttaca
     2281 aatactagtt ttctgataag attaataata acactttaaa tagcgcttaa taaatgaagg
     2341 gggcaagtct tatgacgttt tacaatttca tcatgggttt tcaaaatgat aacacaccat
     2401 ttggtatatt ggccgaacac gttagtgaag ataaagcatt ccctcgatta gaagaaagac
     2461 accaagtaat tagagcatat gtgatgtcta attacacaga tcatcaatta attgaaacta
     2521 caaatagagc tattagctta tatatggcaa attaatttga gtagtaccaa ttatgatgta
     2581 ttagtgcatc ccaaatatct tttgttttaa agtttatttc atcatttctt atcgaaaatg
     2641 gtgtaataat gtctttatct aaccaagtgt tgataagttc atttggtaca ccatctaaca
     2701 acatttcact tttactaatt ataaaacatt cccagtcaag tgaaacattt tgtggattca
     2761 cataattaca ttgattatga tgatccataa acactcactc ctttaaaatt ctgtactctt
     2821 cattgcgttt taccccgtca cattatcttt taaactaaaa tcatcattac ttatgaaaaa
     2881 aatgtacatc aaaagcaaag gttttcgcta ccgaaaaagt ttaaataatg gtttaatata
     2941 tttggtactc attttaataa aaagagaata cattttgagc tatcaatact ttttattgaa
     3001 gaggtgttat tgttggctaa aacgttatat ttaatgcgcc acggacaaac tttgtttaat
     3061 tttaagggac taattcaggg atttggagat tcgccgctaa cagaacttgg aattgctcaa
     3121 gctcaaaagg cacgtagtta ttatgaaact aaggggataa acttcgattt atatgcatca
     3181 tcaacgcaag aacgcgcaag tgacacactt gaaaatgttg cacctaacca atcgtatcaa
     3241 cgttttaagg gactgaagga atggcatttt ggaatatttg aaggtgagtc agtctatcta
     3301 tttgataatc tatacaagcc tgaggactta ttcggagatc gaattgttcc tttcaaagga
     3361 gaggcaaggc aacaagttga agaacgcatt gtgaaaactt tacatgacat tatgtctcaa
     3421 acaaagaata atgcattagt cgtgagtcat ggaacaataa tgggagtatt tttaagatat
     3481 tgccttaaac tagatgaagc attaaagcat aatatcggta attgtaatat cctgaaattt
     3541 gaatatgaca atggaacatt taaatttgtt gagttaattg atccaaattt ataataaata
     3601 aagcgttata catagacaca agtatgtctt ttgtataacg cttttaaaat acaactacat
     3661 aacgctttag aataataatt gaataagttt ttgtaatatc attagagcaa caataataat
     3721 tattatgctt gatattttat tgattattgt taataatttt ccagttttat caattgatcc
     3781 aaccattttt cctaaaattg cgagtaaaaa gaaccataac catgaaacgc taatacaagc
     3841 gattgtaaac gcaattttat tgctgccact atataatgca gcactactac caattacacc
     3901 aattgtatct aaaatagcat gtggattgag taatgaaact gataaagcaa aacttacttg
     3961 tttcattgga gatataattt gagcttctcc atctgttgag ggtttatcat gccaaatggt
     4021 ccaagccata tacatcaaga aaattaaacc aactatataa ataattgctt gaagtacagg
     4081 taaagacata ataatgatag atactcctac cactgcaata ataataagta agctgtctga
     4141 caacccggct gtaattattg caggcaatac atatctatat tttggttgat tagctccttg
     4201 gttaaaaata aatacatttt gtgcacctaa aggtaaaatt agaccaatcg ctaagataaa
     4261 tccatgaata attgcggtta ccattaagtt ttaacacccc taaaacatag aatattctga
     4321 aaaaacttat tgttatcata tcaaataaaa aacaactact caatagtaga gtagttgtat
     4381 gaaaaataga acctatatga tttgaattta tgagaaatgt agaatatata aaactgtatt
     4441 acttattaat caaatcataa aaaagccaat gttcatcgaa ataggtattt ccgattttaa
     4501 ttgcattttt ctcaaaacca agaatgtcga atcctagtgc actatagaaa actttagcac
     4561 ctatgttgtt tgacacaatt gatgtaagta aagattcgta attgttctgc cgtgcataat
     4621 taataatgaa attaatgagc tcgctattaa tcgatttatc gttattagta acaaagttgt
     4681 atttaattaa tgatttatgt tcttttccaa cgtatcgaat ttgttctaag gcagctgttg
     4741 cgataagtgt ttcgttttca taacagccaa atacaataca tttcggtgaa ccttgattta
     4801 aaatgtcatg tattaaggtg tcagtcattg tttgactata atgtgaatct tgagtgaatt
     4861 cttcattgac tgtcgaaaca agtctcttat actcattaaa atcattattc gttaatgttt
     4921 taatttcaat cattactgac ctccttaatc attattaaga aagattttgt actaaaaaaa
     4981 tttcttaatt acatattaaa atgtttatta aaattttgca atcactgatt tatatgcaca
     5041 ttcttgtaaa tggattatca atttaattat atttattttt aagttcagga aattatggaa
     5101 ttggttattg atcgacactg gacttttatt tggagacgtt atgcgaagaa gtcaagccag
     5161 tattggaacc ggtcacattt atgatgacta agggacaatc attttcagtt aaatattgcc
     5221 agaaatttca gtcacgaata gaaaaaataa ccaaccaaaa atttttggtt ggcaaatttg
     5281 aattttatgt gaattttatt aataacgttg aataatctct ttaagttaat gctaatctac
     5341 aacatttaca tttaaatcga cattaatatt tccttgagtc gcttttgaat atggacaaaa
     5401 ttcatgagcc atttgtaaat atttttcagc ttcttcttga gatataacat ttttaattgt
     5461 cgcatcaatt gaaacactta atttaggact ttctgagtct gaatcatctt ctagtctcac
     5521 tgttagtgtt acttctggat gagcatcacg cactttgttt tgctttaaaa ttaggtcgaa
     5581 agcaccgttg aagcaagatg cataacctgc tgcaaataat tgttcggggt tagtagcttt
     5641 accatctgct tgagcaggcg gaacgatatc aatatctaac gctcgatcat cagtataaac
     5701 atgtccttta cgtccgccaa cattcgtcgc tttagtttca taatgtattg ccattcttat
     5761 aacctcctaa tttaaaatac atttatgctt tacccattcg aaaatacctt aatcattttc
     5821 atttatagca ttgtttgatt gaaggataaa aagttgttgt ttacaataaa aataatgagt
     5881 atctgaaatg agggatttac tatgacacat gtggaagtag tagcgactat cgcgccacaa
     5941 ttatctatcg aagaaacttt aattcaaaaa attaatcatc gtattgatgc aatagacgta
     6001 ttagaattac gaattgatca aattgaaaat gtcacagttg atcaagtggc agaaatgatt
     6061 acaaagctga aggttatgca agattcattc aaattattag ttacgtatcg tacaaagtta
     6121 caaggtggct atgggcaatt tataaatgac ttgtatctta atttaatatc agacttagca
     6181 aatatcaatg gcatagatat gattgatata gaatggcaag cagatattga cattgaaaaa
     6241 catcaacgaa tcattaaaca cttgcaacag tataataaag aggtggttat atcacatcat
     6301 aatttcgaaa gtacgcctcc attagatgaa ttgcaattta tattttttaa aatgcaaaaa
     6361 ttcaacccag aatacgttaa attagcagta atgccacata ataaaaatga tgtgttaaat
     6421 ttattgcagg caatgtctac attttcagat actatggact gcaaagttgt tggtatttca
     6481 atgtctaaac ttggactaat aagtagaacg gctcaaggcg tttttggtgg tgcattgact
     6541 tatggttgta tcggagaacc acaagctcca ggacagattg atgttactga tttaaaagca
     6601 caagtgactt tatactaata aaatgaatta ggttgctttt gtgtaagtgc tgtcttataa
     6661 ttgagaagta ttatcattgt tcgtggagga gcgattttag atggaattac aacaagcaat
     6721 agctaataga agaagtgtga aaaaatttaa aagagatatg cacatagatg acgcattgct
     6781 atatcaagca attgagaaag ctgctgatgc tccaaatcac ggaatgaggg aaccatggag
     6841 agttgtgcat gttccgaaag acagattagg agatatgagt aaggatattt ctaaatttgc
     6901 atttcctaat gaattagata agcaacaatg tcattatgat gcagtaacga aactaggtgg
     6961 catgttattg cttattttaa aaacagatcc aagacaacgt caaaatgatg aaaactactt
     7021 tgcatttggt gcatatgcac aaaatcttat gttgttactt tatgaagcgg ggataggtac
     7081 atgttggaaa tcgccattat atatctatga tcctaaagta agaaaaacac ttggtataaa
     7141 gaaagatgaa gttcttgctg gattcttata tttaacggat ttagaagaag atatgcctaa
     7201 agcaccacgt aaaaatagaa acttaattac attatattaa tatgtataat tatagaaaac
     7261 attaataaaa gctgagacat gaattgatgg acatctatcg agttagagat ttaatctaat
     7321 ttactagagt cggtacaatc acagtctcag ctttttattg tgaagtatat acacatttgt
     7381 attttagtat ttatttaaaa gtttctgcta aaaatgattc aacttgttca ggtgacttag
     7441 catttgctga atgaaggtgt gcaattttgt cgccgttttt aaatactagc aagctaggga
     7501 tacccataac ttcattttca acaactacat cttctaattc atcacgatta acagtatacc
     7561 attggtaatc attatattgt tctacgattg ggtcaatcca taaatccata gcacgacagt
     7621 ctgggcacca tcctgcctca aatttaacaa ttacaggtgt atcgctatta attatagatt
     7681 taaatgattc attacttttg attgcttgca ttgtaacaac tcctctagat agtttaataa
     7741 tttttattat agctaaattt atatcataat aaaaaatttt agcttcaaaa tgaaagcctt
     7801 ttgctatgga aaatgatata tttattttaa atacataaag gaggttgcag tcgcatgatt
     7861 aaattttacc aatataagaa ttgtacaact tgtaaaaagg cagcaaagtt tttagatgaa
     7921 tatggcgtaa gttatgaacc aattgatatc gttcaacata cacctacaat aaatgaattt
     7981 aaaacaataa ttgcaaatac aggcgtagaa attaataaat tgtttaatac acacggtgcg
     8041 aaatatcgtg agcttgattt gaaaaataaa ttacaaactt tatcagatga tgaaaagtta
     8101 gagttgttat catctgatgg tatgttagta aagcgtcctc tagcagtaat gggcgataag
     8161 ataacattag gatttaaaga aggtcaatat aaagagactt ggttagcgta agtgaaatgt
     8221 aaacgtttac taaatatctc gatatttaga ttcattacat gtaaaatgaa ataagctata
     8281 caattgttaa tttttataaa tatagttgaa tagcatctag ccttatggca tcattaatga
     8341 tgtaaagatt aattaggagg ggattctctt ggcagtacca aatgaattga aatattcaaa
     8401 agagcatgaa tgggttaaag ttgaaggtaa tgtagcaaca attggaatca cagaatacgc
     8461 acaaagcgag ttaggtgata ttgttttcgt tgaattacca gaaacagatg atgaaattaa
     8521 tgaaggggat acgtttggta gcgtagaatc agttaaaact gtatcagaat tatatgcacc
     8581 aatctctggt aaagtagttg aagtcaacga agaactagaa gatagtcccg aatttgtaaa
     8641 tgaatctcca tacgaaaaag catggatggt aaaagtagaa attagtgatg aaagtcagct
     8701 tgaagcttta ttaacagctg aaaaatattc agaaatgatt ggtgaataat caccgtgtaa
     8761 ctccttaatc taagattgag gagtttattt ttagtctgag taagtaaata atatgaaaga
     8821 aaatttatta ggcactatta tttggagtat tgctacattt tattattcaa gaatgatgaa
     8881 aataatgaat ttagctattt taaaaataaa aattggggga agttaatatg ctaaacattc
     8941 aagacgttag tcatctttct aaaaaggagc aaaaagcata taaccgtttc gtagaatctg
     9001 tagaaaacgg taatttacca gtactaccat gtattgaaat ggatttaaaa gagatgcaag
     9061 aagaaacttt aagccagagt aagattggtg gaatgccatt tttaaaatct tttaaagata
     9121 taccattaga tgaaaataat gtaccaatgg tattgttagc acagattaat ttgaatgatc
     9181 ttccagaaca acaagaatta tttcctgtaa atgaagggat attgcagttt tggattagtt
     9241 cagaagatca aatgtatggt atgtctgaaa atttaaaggg aaacaatata aactcaaggc
     9301 ttgtttatat aaaagagcca attacagatt tatcactcga aaatattcaa gtgcatttga
     9361 agtcattaga tgctgataat gaggatatcc cgttcagtgg agcattttct atagaattta
     9421 gattgtcgaa acaaactatt acatgtactg attataagta cgatgaggac gtgcttgcat
     9481 tgtggaataa agtcaatcca tccttcgcgc taaaatcgat gtttggtgga tatgatgaat
     9541 taatggaacc tgtgtgtaac acatttactg ctaaggagcc atttaatcaa cttggtggtt
     9601 atccatattt tgaccaaata gatccaagaa cgaacgatca agaactgaaa atgtatgata
     9661 gagtcttact gcaaattgat tctacaagag atggtaattc ttcgattata tggggtgatt
     9721 taggtattgc caatatctta gtgaaatcta ctgaccttga ggctatgaag tttgatgatt
     9781 acatgtattc atgggattgc agctaagaga atcataaaaa tatattactt taataagtgt
     9841 agtatctata gatcaatcta gggagtggga cagaaatgat attttcgcaa aatttatttc
     9901 gtcgtcccac cccaacttgc attgtctgta gaaattgaga atccaatttc tctttgttgg
     9961 ggcccatccc caacttgcat tgcctgtaga atttcttttc gaaattctct gtgttggggc
    10021 ccctgactag aattgaaaaa agcttgttac aagcgcattt tcgttcagtc aactactgcc
    10081 aatataactt cgtagagcat agaacattga tttatgtccc agcctgtttt cataagccac
    10141 agctaatgtg tatttaaaaa taggaataca tgagtaaaac tcatgcataa gaaatactaa
    10201 tttctaaaga aaaagtattt ctttatgttg ggccccccaa cttgcacatt attgtaagct
    10261 gactttccgc cagcttctgt gttggggccc cgccaacttg cacattattg taagctgact
    10321 taccatcagc ttctgtgttg gggccccgct ataattgaaa agtttgttat aggtgtattt
    10381 tcttttggtt aactattgtt aatataacat tgtagatttt aggatgttga tttttgactt
    10441 agcctttgtc tgcttatgtt aaatgttcca gctagtcaaa cattgagttt gtaattatta
    10501 tattaagcta gtttaaattt tttgtgattt atgttttatt cataccaatt ttgtgaaatg
    10561 atacagtgac agatgtttat tgattttaaa gggtgatgat gatggctatt gtaaataaag
    10621 tgataattgt tgaaggaaaa tctgataaaa aaagggtgca acaggttatt gcagaaccag
    10681 tcaatattat ttgtactcat ggaacaatga gtatagataa gcttgatgat atgatagaat
    10741 cactgtatga taaacaagtt tttgtattag ccgattctga tgacgaagga gatcgaatta
    10801 gaaattggtt taaacgttat ttgagtgaaa gtgaacatat atttattgat aaaacttact
    10861 gtcaagttgc gaattgcccc aaacaatatt tggcgcatgt actttcaaaa catggcttta
    10921 cttgtaagaa agaaacacct cttttaccga atataaataa tgaaaggtta gttttagtaa
    10981 atgaataatt cattagacat caaagatgta actacatttt atgaggaaga caaacattta
    11041 atctttggtt atacaccaac gtgtggtact tgtaaggttt cagaaagaat gttagacatt
    11101 gctaatgaaa tattgcagtt accattattg aaaatagatt taaactttta tcctcagttt
    11161 tgtaaagata tgcaaatcat gtctacgccg attttattgt tgatgaataa agataaagaa
    11221 gtaaaacgaa tttatgcatt taaatcggtg actgatttgt tagaaaattt aaaatagtta
    11281 ttgacgaaat tttactaagg tgttaggatt aatacaaatt aaatgatgcg taaactctta
    11341 tcgagagtgg tggagggatg tgccctacga agcccggcaa ccgtcttata tagaaatggt
    11401 gccaattcac ataaagtttt aacttttgaa gatgagagaa acaatactac tattgctttc
    11461 tcaatttttc tatcgatatt gagaaagcat tttttatttt attaagcaac acagggagga
    11521 atcaacgtga ttgaattaaa agaagttgtt aaagaatatc ggactaaaaa taaagaagtc
    11581 cttgctgtag atcacgttaa tttatcgatt cgagcaggat cgatttatgg cgtcattggt
    11641 ttttctggag caggaaaaag tactttgatt cgaatgttta atcatttaga agcgcctaca
    11701 tcaggtgaag ttattataga tggagaccat ataggtcaat tgtccaaaaa tggattaaga
    11761 gcaaaaagac aaaaagtaag tatgatcttc caacatttta atttgttatg gtcaaggact
    11821 gtgttaaaaa atattatgtt tccgcttgaa attgcaggtg tccctagaag gagagctaag
    11881 caaaaagcat tagaacttgt cgaactcgtc ggtttaaaag gtagagaaaa ggcttatcca
    11941 tcagagttat caggtggaca aaagcaacgt gttgggattg cacgagcgtt agctaatgat
    12001 ccaacggtct tgctttgtga tgaggcaaca agtgcacttg atccgcaaac aacagatgaa
    12061 attttagatc tactactaaa aattagagaa caacaaaatt taacaattgt actaattacg
    12121 catgaaatgc atgtcattcg tcgtatttgt gatgaagttg cagttatgga aagtggtaaa
    12181 gtgatagaac atggaccggt gacacaggtt tttgaaaatc cgcaacacac tgtgacaaaa
    12241 cgatttgtga aagaagattt aaatgatgat ttcgaaacat ctttaacaga attagagcca
    12301 ttagaaaaag atgcttatat cgttagatta gttttcgctg gttcaacaac aaccgagcct
    12361 attgtatcga gtctatcaac tgcctatgat attaaaatta atattttaga agcaaatatt
    12421 aaaaatacaa aaaatggaac agtcggcttt ttagttctgc atattccata tatttcaagt
    12481 gtagatttcg gaaaattcga aaaagagtta attgagcgac aagttaaaat ggaggtgtta
    12541 agacatgggt aaatcattta gtgaaattat aaatgaaatg attacaatgc ctaatattca
    12601 gtggccagaa gtttggactg caatagtcga aacactatac atgacagtcg tctcaactat
    12661 atttgcattt atactcggtc ttattttagg tgtgttatta ttcttgtctg ctaaaggtaa
    12721 gtctatcggt gcaaggttat tttattctat cgtttctttc attgttaact tatttagagc
    12781 gataccattt attattttaa ttttattatt aattccattt acaagtttga tacttggaac
    12841 gataagtggt ccgacaggtg cgttaccagc cttgattatt ggcgcagcac cgttttatgc
    12901 aaggctcgta gaaattgctt ttaaagaaat tgataaaggt gtcatcgaag cggcctggtc
    12961 aatgggtgcc aatacttgga tagtaattcg taaagtcctc ttacctgaag ccatgccagc
    13021 gctagtgtct ggcattacag ttacagcaat cgctttagtt ggttcaacag cagttgcagg
    13081 tgtaattggt gccggtggtt taggaaattt agcatactta acaggtttca ctcgaaatca
    13141 aaatgatgtc attttagtat caactgtttt tattttaatt attgtattta taatccaatt
    13201 cattggggat tggcttacaa ataaacttga taaacgataa attggggggt tcattttatg
    13261 aaaaaattat ttggtcttat tttagtatta acatttgcag ttgtattagc agcttgcggt
    13321 aatggaaaca aaagtggcag tgacgataag aaaataacag taggtgcttc accagcacca
    13381 catgctgaaa ttttagaaaa agcaaaacca ttattagaga aaaaaggtta tgacctagat
    13441 attaaaacaa ttaacgatta cactacgcct aataaattac tagataaagg tgaaattgac
    13501 gcaaactatt tccaacatac accatattta aacacagaga aaaaggataa aggttacaaa
    13561 atcgtaagtg ccggtgatgt tcacttagaa cctatggctg tatactctaa aaagtataaa
    13621 agtttaaaag aattaccaaa aggtgcgaca gtttatgtgt ctaataatcc agctgaacaa
    13681 ggacgcttct taaaattctt cgttgatgca ggtttaatta agatcaaaaa aggcgtaaaa
    13741 attgaagatg ctaagtttag tgatattaca gagaataaaa aagatattaa gtttaataat
    13801 aaacaatcag cagaattctt acctaaaatt tatcaaaatg aagacgctga tgctgttatc
    13861 attaattcaa actttgcaat cgaacaaaaa ctaaatccta aaaaagattc tattgctgta
    13921 gaaagtgcga aagataatcc ttatgcaaac ttaattgctg ttaaagaagg acatcaagat
    13981 gataagaaaa tcaaagcatt aattgaagta ttacaatcta aagatattca agacttcatt
    14041 aatgaaaaat acaacggtgc agttattcct gctaaataaa tcatattaat ggctcagtaa
    14101 cgtgatgttg ctgggctttt taatttaaac aggtatttat atgatattta ggaatgagat
    14161 gctattacgg ataaagtaaa atcctatatg catgcgtgct actcatttat tcttattttt
    14221 aatttcacat ggatagtgac tactacatca taaatcatta gtgattcttt attatttcag
    14281 tcccactccc tcaagttaat gatgaatcta tttcgctagt tataaaatga cgtcaaatca
    14341 atatcaaaaa ttatttaagt aaaatgttta gataattttt cagtgggtaa gtattatata
    14401 taacatttaa ttattccgag gaggcattta ttatggcaga cgaaagtaaa tttgaacaag
    14461 caaaaggtaa tgttaaagaa acagtaggta atgttactga taataaaaat ttagaaaacg
    14521 aaggtaaaga agataaagct tctggtaaag cgaaagaatt cgttgaaaat gcaaaagaaa
    14581 aagcaactga ttttattgat aaagtaaaag gtaacaaagg cgagtaattt tactttttta
    14641 ttcctaatac actgcacatg ccacttagtc ggtataacca tcggctaggt ggtttttgta
    14701 ttaaaaaagt ggataccaaa atttattaat aattatttta atgttagaaa aaaactaaat
    14761 aaaaactcgc taatgatatc caataatatg tatacaaaac gagacatata ttgcatatga
    14821 ttaacgagat actgaatata ttttatcacc cctaaaatga ttattcattt tcagcggtaa
    14881 ttcgacctaa agtcaaactt acaataaaac cgatgataaa tactactaat gaaacgaacc
    14941 acatcacgat attagttggt aaacctggaa atactgcaaa gagggagcca acaacaaaac
    15001 caatgattaa tgcaaaagtc attagtttat gatgtgttag gaaatactgg ataattttgc
    15061 ttgaaataat gaatccagca agcaccccaa atccgactgc aagtagtata ggaagaccgg
    15121 taaagttaag tttaacaact tcagatattg ctagcatgac cgtaccatag acgccaaata
    15181 ctaataacat aaatgatcct gaaatacctg ggagtaacat agcgctagat gcacacatac
    15241 ctgcaataaa gtatttaata ataagaccag ttgatagagt aagcgtttct ccagcatgtt
    15301 tatcaccatt attcattaat gtaataacaa ttaagatagc gataccagct ataaccatca
    15361 tgtaatgttt agttgtaaat gacgttttat agttagaaat tttcaataaa tatggaacga
    15421 taccaatgat taatccacca aagaaaaaca tagttggaat atggtgttgg cttaataaat
    15481 aattaaaaag attacttagt gatcccattg ccagtaacat tccaattata atggggatta
    15541 aaaatgtaaa acttggccaa aaacgtcgtg agaatatgcc gctaattgaa gcgataaatt
    15601 gattgtaaat acctaacaat aatgcgatag tcccaccgct aacaccaggt accaagtcac
    15661 tcgttcccat agcaaaacct tttagaatat taatccattt aaattgttgc atgaataact
    15721 cctttcaaac gattggaata aaatcataaa tagcatcata ccatattaca aatgtcctag
    15781 tgaaatgata acatatttta aattcataaa atccattgag aaattatgtg cacttattat
    15841 catttatatt tttaaagaga gcggattaga gttgtacttt agagttatta aaaataataa
    15901 aaagggttta agttgtttat attaaggtat aagtaagtta taattaactg aacgcattat
    15961 tacaaagtct ttttgactac aaattaaaat tattataaac tagttaagaa aactttatat
    16021 tttacggagg gaatataaaa tggcatcaac attagaaatc aaagacctac atgtgtctat
    16081 tgaggataaa gaaatcttaa aaggtgttaa cttgacaatt aacactgatg aaatacatgc
    16141 gattatggga ccaaacggga caggtaaatc aactttatca tctgcaatta tgggacaccc
    16201 aagctatgaa gtaactaaag gagaagtact tttagacggt gtaaatattt tagaattaga
    16261 agttgatgaa agagcaaaag caggattatt cttggcaatg caatatccat cagaaattac
    16321 aggtgttaca aatgctgatt tcatgcgttc agcaatcaat gcgaaacgtg aagaaggaca
    16381 agaaatcaac ttaatgcaat ttattaagaa attagataaa aacatggatt ttctagacat
    16441 agataaagac atggcacaac gttatttaaa tgaaggtttc tcaggtggag agaagaaacg
    16501 taacgaaatc ttacaattaa tgatgttaga acctaagttt gcaatcttag atgaaatcga
    16561 ttcagggtta gacatcgatg cattaaaagt tgtatctaaa ggtattaacc aaatgcgtgg
    16621 ggaaaacttt ggtgcattaa tgattacaca ctatcaacga ttattaaatt acattactcc
    16681 tgataaagta catgtaatgt atgctggtaa agtcgttaaa tctggtggtc cagaattagc
    16741 aaaacgtctt gaagaagaag gatatgaatg ggttaaagaa gagttcggtt cagctgaata
    16801 atcttattaa tacagtatcc atgagatgtt catctatata tgatgaaaat gaacatttat
    16861 acgaaatagt aaatttcatc aagtaggagg aaaaagttat gacaactgat attttgaaca
    16921 tttctgaaga acaacttgtt gattattcta aagcccacaa tgaaccttct tggatgacag
    16981 aattacgtaa aaaagctttg aaattaacag aaactttaga aatgccaaaa cctgataaaa
    17041 caaaattaag aaaatgggat tttgattctt ttaaacaaca cgatgtaaaa ggtgatgttt
    17101 atcaatcttt atcacaatta cctgagtcag taagagaaat tattgacgta gatcattcta
    17161 aaaacttagt aattcaacat aataatacga ttgcgtacac acaagttgat gataatgcat
    17221 cgaaagatgg cgttatcgtt gaaggtttag cagacgctct tatgaaccat agtgatttag
    17281 tacaaaagca ctttatgaaa gatgcagtaa cagtagatga acatcgtatc acagcgctac
    17341 acacggcatt agttaatggt ggcgtatttg tttatgttcc taaaaatgta gttgtagaac
    17401 atccagtaca atacgttgtg ttgcacgacg acaaaaatgc aagcttttat aaccatgtta
    17461 tcatcgttac tgaagaaagc gccgaagtca catatgttga aaattactta tcaaatgcat
    17521 ctggtgaagg aaatcaatta aatattattt ctgaagtgat tgctggtgca aattcaaata
    17581 tcacatatgg ctcagtggac tatatggata aaggctttac aggtcatatc attcgacgtg
    17641 gtattactga agcggatgcc tcaattaatt gggcactagg tttaatgaat gagggtagcc
    17701 aaattattga taatacaaca aatttatttg gtgatcgttc aacaagttca cttaaatcag
    17761 tagttgtagg tacaggagaa caaaaaatta atctaacatc taaaatcgta caatatggta
    17821 aagaaacaga tggttatatc cttaaacatg gtgttatgaa agaacatgca tcatctgtat
    17881 ttaatggtat cggctacatt aagcatggtg gaactaaatc aattgctaat caggaatcac
    17941 gtgtattaat gttatctgaa catgctcgtg gtgacgcgaa tcctatttta ttaattgatg
    18001 aagatgatgt acaagctggt catgctgcat cagtaggtcg tgttgatcca gatcaacttt
    18061 actatttaat gagtcgtggt atttctcaaa gagaagcgga acgtcttgtt atacatggtt
    18121 tcttagatcc agtagtacgt gaattaccta tcgaagacgt taaacgtcaa ttgagagaag
    18181 taattgaacg caaagtttct aaataatatt ttgaaaataa aagtttgtaa tagatataga
    18241 ctgtcgatat tggtataaga ctaatacaac gtcagtattt aaatgattag gatttttatt
    18301 taagaaaggt cgtgaatgaa gtggccgaac actcatttga cgttaatgaa gtaatcaagg
    18361 attttccgat attagatcaa aaagtcaatg gcaaacgttt agcatatctt gattcaacag
    18421 cgacaagtca aacgcctatg caagtgttaa atgttttaga ggattactac aagcgttata
    18481 attcaaacgt tcatcgtggt gttcatacat taggatcatt ggcaactgat ggttatgaaa
    18541 atgcccgtga aaccgttcgt cgttttatta atgcgaagta ttttgaagaa atcattttca
    18601 cacgcggaac aactgcgtcg attaaccttg tagcacatag ctatggtgat gcaaatgttg
    18661 aagagggcga tgaaattgtt gtcactgaaa tggagcatca tgccaatatt gttccttggc
    18721 aacagttagc aaagcgtaaa aatgcgacat tgaaatttat accaatgaca gctgacggtg
    18781 aattaaacat cgaagatatt aagcaaacga ttaatgataa aacaaagatc gttgctattg
    18841 cacatatttc taatgtactc ggtacaatta atgatgttaa aaccattgca gaaatagctc
    18901 atcaacatgg cgcaattatc agtgttgatg gggcgcaagc agcaccacat atgaaacttg
    18961 atatgcaaga aatgaatgct gatttttata gttttagtgg tcataaaatg cttggaccaa
    19021 caggtattgg cgtattattt ggtaaacgtg agttactaca aaaaatggaa ccgattgagt
    19081 tcggtggtga catgattgat tttgtaagta agtatgatgc aacatgggct gatttaccta
    19141 ctaaatttga ggcgggtact ccattaattg ctcaagcaat tgggcttgca gaagctattc
    19201 gctatttaga acgcataggt tttgatgcaa ttcataaata tgaacaagaa ttaacgatat
    19261 atgcttatga gcaaatgtct gcaattgaag gaattgaaat ttatggcccg cctaaggatc
    19321 gtcgtgcagg tgtaataacg tttaatttac aagatgtaca tccacacgat gttgctacag
    19381 ccgtagatac agaaggtgta gcggttagag ctgggcatca ttgtgcgcaa ccgttaatga
    19441 aatggttaaa tgtgtcttca acagctagag cgagttttta tatatacaac acgaaagaag
    19501 acattgatca gttaataaat gccttgaaac aaacgaagga gtttttctct tatgaatttt
    19561 aataatctag atcaattata tagatctgtc attatggatc attataaaaa tcctagaaat
    19621 aaaggtgtat tagataacgg gtctatgaca gtagatatga ataacccgac atgcggtgac
    19681 cgtatacgac taacatttga tatagaagac ggcattataa aagatgctaa gtttgaaggt
    19741 gaaggttgtt cgatttcaat ggcaagtgca tcgatgatga cacaagctgt taaaggtcat
    19801 tcacttggag aagcaatgca aatgagccaa gaatttacga aaatgatgct tggtgaagac
    19861 tatgtgatta cagaagaaat gggagatatt gaagcattgc aaggtgtatc tcaattccca
    19921 gctcgtatta aatgtgccac attagcttgg aaagcattgg aaaaaggtac tgttgctaaa
    19981 gaaggtaaag cagaaggtac gactgaagaa gaatagaatg ctgttaatca tagatgattt
    20041 tgatattaga catataaaag tataaaaatt tttataagat gtcatgtcat tgttataata
    20101 tggtttacat catgaattaa aaacttacgc acgccgttgt aaatatattt ttaaggagtg
    20161 attgaaatgg ctaaaaaagc acctgatgtt ggggattata aatatggatt ccacgacgat
    20221 gatgtatcca ttttcagatc agaacgtggt ttaactgaga atatcgttag agaaatttct
    20281 aacatgaaaa atgagccgga atggatgtta gatttccgtc ttaaatcatt aaaattgttt
    20341 tataaaatgc caatgcctca atggggtggc gacttatcag aattgaattt cgatgacatt
    20401 acttactatg taaagccttc agaacaagct gaacgttcat gggatgaagt gccagaagaa
    20461 attaaaagaa ctttcgataa attaggaatt cctgaagctg aacaaaaata tttagctggt
    20521 gtttctgctc aatatgaatc tgaagttgtt taccataata tggaaaaaga acttgaagaa
    20581 aaaggtatta tctttaaaga tacagatagt gctttacaag aaaatgaaga attattcaaa
    20641 aaatactttg cttctgtagt acctgcagca gataacaaat ttgcggcgtt aaactcagca
    20701 gtatggtcag gtggttcgtt catttatgta cctaaaaata tcaaactaga tacgccacta
    20761 caagcttatt tccgtattaa ctctgagaac atgggtcaat ttgaacgtac attaatcatt
    20821 gctgatgaag gtgcttctgt acattacgta gaaggttgta ctgcaccagt ttatacaact
    20881 agttctttac actctgctgt tgtggaaatc attgtgcata aagatgcgca cgttcgttat
    20941 actacgattc aaaactgggc gaacaatgta tacaatttag ttacaaaacg tacttttgtt
    21001 tatgaaaacg gaaatatgga atgggtagat ggtaacttag gttctaagtt aacgatgaaa
    21061 tatccaaact gtgttctttt aggtgaaggt gcaaaaggta gtacattatc tattgcattt
    21121 gctggtaaag gacaagttca agatgccggt gctaaaatga ttcataaagc gccaaataca
    21181 tcttcaacga ttgtttctaa atctatttct aaaaatggtg gtaaagttat ttatcgcggt
    21241 attgttcatt ttggacgtaa agcaaaaggt gctcgttcaa atattgaatg tgatacatta
    21301 atcttagata acgaatcaac atcagataca attccatata acgaagtatt caacgatcaa
    21361 atatcattag aacatgaagc caaggtttca aaagtttctg aagaacaatt attttatcta
    21421 atgagtcgtg gtatttctga agaagaagcg acagaaatga ttgttatggg attcatcgaa
    21481 ccatttacaa aagaacttcc aatggaatac gcggtcgaaa tgaaccgttt aatcaagttc
    21541 gaaatggaag gtagtattgg atagctttaa accgcgttgt taagccattc ttgacttccg
    21601 gaaatgggta ttgataccat tttgatactg aatataacaa aaagccacat tactgtggct
    21661 ttttttgttt tataactaaa tcggattgat agataagctt tgtacttatt tatatcagtc
    21721 cgattttttg attggtgtaa aaaataatca ttgatggtgg ataaagcgac aacacaaata
    21781 caatatgatt gtggcattag agtgctggtc tttattaaat taattgaaaa ctacatcaaa
    21841 tattctttaa agataattcg atattagttc gattaagatt cgttgtataa gtgagttaaa
    21901 ataagaaaac tattaataat attaagttca ctacagatgt tgctaatgga ccataagttt
    21961 taaagacatc ttcactttta taaccaacaa tcgcatctaa aaattgaact aaaatcattg
    22021 caatggatat agttatcaaa aatatagcac tatgaatgac taaagaaaaa atagctaata
    22081 aaaataaagg taagcttcga ctaagtgcat aatatgcatt tatattatga ctagatgcac
    22141 atgcttgaat tgaataacct aaacttacac tggcactaat gattgtaaat attgctaaaa
    22201 caaaatacat gttaatcctt ctttctatat ttgaatataa acaagtactt gtctaaagat
    22261 atttaaaaga taattagaat aaatttatga gaaactggtt gttatcatta taatggtttc
    22321 aaatgattat aactatgtca taaactgaat ttgttgaaat ttttcattat gtaaatttat
    22381 taataacaaa cagctcgaac tatagcatca ttttactaat gaatgcatta aagtaactat
    22441 gattaaaaat gcatattaat tatcattatt aagtctatta tatataatga attttaactg
    22501 gtttattaaa cgagaacgtc gggaattaag taactacaat aaaaataaga tatgacaata
    22561 aggagactac acgcgtgatc attgccataa ttatattgat atttatttcg tttttctttt
    22621 caggaagcga gacggcatta acggctgcca ataaaacaaa atttaaaact gaagctgaca
    22681 aaggtgataa aaaagcaaaa ggcattgtaa agttacttga aaaaccaagt gagtttatta
    22741 caacgattct aattgggaat aatgtcgcga atattttatt accaacactt gttacaatta
    22801 tggctttacg ttgggggatt agcgttggta ttgcatcagc tgttttaaca gttgttatca
    22861 ttttgatttc cgaagtgatt cccaagtctg tcgctgcaac atttccagat aaaataacaa
    22921 ggcttgtata tccaattatt aatatttgtg tcattgtgtt tcgccctatc acattacttt
    22981 taaataagtt gacggacagt attaatcgaa gtttatctaa gggtcaacct caagaacatc
    23041 aattttcaaa agaagaattt aaaacaatgt tagcaattgc tggacatgaa ggtgctttaa
    23101 atgaaattga gacgagtagg ttggaaggtg tcattaattt tgaaaattta aaagtaaaag
    23161 atgtagatac aacacctaga attaatgtga cggcatttgc ttcaaatgcg acatacgaag
    23221 aagtttatga aacggttatg aataagccat acactagata tccagtgtac gagggagata
    23281 ttgataacat tattggggtg tttcattcta aatatctgtt ggcttggagt aataaaaaag
    23341 aagatcaaat tacaaactat tcagctaagc cattatttgt gaatgaacac aataaagctg
    23401 aatgggtatt acgtaagatg actatttcta gaaaacattt agcaattgtg ttggacgaat
    23461 ttggtggtac cgaagcgata gtgtcacatg aagacttaat tgaagaatta ttaggtatgg
    23521 aaattgaaga tgagatggat aaaaaggaaa aagaaaaact ttctcaacag caaattcaat
    23581 ttcaacaacg gaaaaatcgc aacgtatcta tataaggagc gaacagctat gtggaataag
    23641 aatcgactta ctcaaatgtt aagtattgaa tatccaatta tacaagcagg tatggcagga
    23701 agtacgacac cgaaattagt tgcatcagta agtaacagtg gtgggttagg cacaataggc
    23761 gcaggttact ttaatacgca gcaattggaa gatgaaatag attatgtacg ccaattaacg
    23821 tcaaattctt ttggcgtaaa tgtctttgta ccaagtcaac aatcatatac cagtagtcaa
    23881 attgaaaata tgaatgcatg gttaaaacct tatcgacgcg cattacattt agaagagccg
    23941 gttgtaaaaa ttatcgaaga acaacaattt aagtgtcata ttgatacgat aattaaaaag
    24001 caagtgcctg tatgttgttt tacttttgga attccaaatg aatctattat agaaagattg
    24061 aaagaagcaa acattaagct aataggtaca gcaacaagtg ttgatgaagc tattgcgaat
    24121 gaaaaagcgg gtatggatgc tatcgttgct caaggtagtg aagcaggtgg acatcgtggt
    24181 tcatttttaa aacctaaaaa tcaattacct atggttggaa caatatcttt agtgccacaa
    24241 attgtagatg tcgtttcaat tccggtcatt gccgctggtg gaattatgga cggtagagga
    24301 gttttggcaa gtattgtctt aggtgcagaa ggggtacaaa tgggcactgc atttttaaca
    24361 tcacaagata gtaatgcatc agaactacta cgagacgcaa ttataaatag taaagaaaca
    24421 gatacagtcg ttacaaaagc gtttagtgga aagcttgcac gcggtatcaa caataggttt
    24481 atcgaagaaa tgtcccaata cgaaggcgat atcccagatt atccaataca aaatgagcta
    24541 acaagtagca taagaaaagc cgcagcaaac atcggcgaca aagagttaac acatatgtgg
    24601 agtggacaaa gcccgcgact agcaacaacg catcccgcca acaccatcat gtccaatata
    24661 atcaatcaaa ttaatcaaat catgcaatat aaataatcga ccgcaatcca caaaagcaca
    24721 agcactccca aacattattt tagtgcttgc catttttgtg gattgcgttt ctattttacc
    24781 aatctagtca aacgaaatta tcaaactaaa gttcgctgaa atgattatag tcaaacgaaa
    24841 acatcaaact aaagttcgct gaaatgatta tgatcaaacg aaattatcga gctgaaggtc
    24901 accgaaatga ttataattaa acgaaattat cgagctaaag ttcactgaaa tgattataat
    24961 caaacgaaaa catcaagctg aagatcgccg aaagatttta atcaagcgaa aacatcaaat
    25021 taaagttcgc tgaaatgatt atgataaaag ttatatggta tgatgacatt ggtgatatat
    25081 atgataaaca tcggattaac aggttggggt gatcactatt cattatatga agatttagaa
    25141 cgccaaaccg ataaacttaa aacatatgct ggacattttc cggttgtcga attagatgcg
    25201 acatactatg cgatacaacc ggaaagaaat atattgaaat ggataaaaga aacgcctgat
    25261 acatttgaat ttgtggtcaa aattcatcaa gcactcacat tgcatgcaga ctacaaaaca
    25321 tttgcagata caaggcaaga actatttgat caatttaaga atatgttaga gcccttacat
    25381 acacagaaaa aattagcaat ggtattggtt caatttccgc catggtttga ctgcaatgca
    25441 caaaatatca aatatatttt gtatgtaaga cagcaattac aagcatttcc aatgtgtgta
    25501 gaatttaggc atcaatcatg gtttagtgat gcatttaaag aacaaacatt ggcattttta
    25561 acagaacatc aaatcattca tgcagtagtt gatgaaccac aagtgaaaga tggcagtgta
    25621 cctttagtca atcgaatcac aaatgaaatt gcgtttgtac gttatcatgg acgtaatcat
    25681 tacggttgga ctaagaaaga tatgtcagat caagaatggc gagatgtacg ctatttatat
    25741 gattataatg agcaagaatt aatagacttg gcacaaaagg cacaaatatt agcacaaaaa
    25801 gctaagaaag tttacgtcat atttaacaat aattctggtg gtcatgcagc aaataatgcc
    25861 aaaacatatc agcgattatt gaatatagaa tatgaagggt tagcaccaca acaattaaaa
    25921 ttattttaag aggcgacgac tatgttatta acaattacat tattagtttt aatcggaggt
    25981 ttgtcagcga ttatagggtc tatcgtaggc attggaggcg gtattattat cgttccaaca
    26041 atggtttacc tcggtgttga acatggatta ctacataata ttacaacaca agtagcgata
    26101 gggacgtctt cagtcattct aattgtgaca ggactttctt catcacttgg atatttaaaa
    26161 acaaaacaag ttgatattaa aaatggttcc atctttttat ttggactatt accaggttca
    26221 ttgcttgggt ccttcattag tagatattta acatttgagt catttaattt atattttggt
    26281 atctttttaa ttttcgtagc cattttatta atggtaagaa ataagattaa accgtttaaa
    26341 attttcgata aacccaagta tgaaaagact tatgtagacg ctaaaggtaa aacatatcat
    26401 tatagtgtgc caccattgtt tgcttttatt acaacgtttt taattggtat attgacaggt
    26461 ttatttggta ttggaggtgg cgcactaatg acgccactaa tgcttattgt atttagattt
    26521 ccacctcatg tagctgttgg aacaagtatg atgatgattt tcttttcaag tgtcatgagt
    26581 tctatagggc acattgctca aggtcacgta gcttggggtt atgcaatcat tttaattatt
    26641 tctagttatt ttggtgcgaa aatcggtgtc aaagtgaatc aatcaattaa gtcagatacg
    26701 gtagtaacat tattgagaac agtaatgttg ttaatgggta tatatttaat tattcgagcg
    26761 ttgatttaat acaactttaa aaggaggacg tcaatttgag gcttacaatt tatcatacga
    26821 acgatattca tagtcattta catgaatacg aacgcattaa agtatatatg gcagaacaac
    26881 ggccacgact taatcatcct tctttatatg ttgatctagg tgatcatgta gatttatccg
    26941 cacctataac tgaagcaact ttaggtaaaa agaatgtggc attactaaat gaagcaaaat
    27001 gtgatgttgc aacaatcggt aataatgaag ggatgaccat ttcacacgaa gctttaaatc
    27061 acctttacga cgaagcaaaa tttatagtga catgtagcaa tgttatagat gaatcaggtc
    27121 atttaccaaa taatatcgtt tcttcttata ttaaggatat ggacggtgtg aaaatactat
    27181 tcgttgcagc gacagcacct tttaccccat tttatcgtgc actagattgg attgttaccg
    27241 atccacttga atctataaaa gaagaaatta aacatcaacg aggtaaattt gatgtaataa
    27301 tcgtgctaag tcattgtggc attttcttcg atgaaacatt atgccaagaa ttgcctgaaa
    27361 ttgatgtcat ttttggtagt catacgcatc attattttga acatggtgag atcaataatg
    27421 gtgtactgat ggcggcagct ggaaagtatg gtaattatct tggagaggtt aatttaactt
    27481 ttgaggcaca taaagtagta cataaaactg caaagattat tcctttagaa acattacctg
    27541 aagttgaaac ttcatttgaa gaagaaggaa aaacgttaat gtccaattca gtaattcaac
    27601 atccagtagt gcttaagcgt agtatgaatc acataactga agctgcatac ttattagctc
    27661 aaagtgtttg tgagtataca catgcacaat gtgccatcat caatgctggc ttactcgtta
    27721 aagatattgt aaaagatgaa gtgacagaat atgacattca tcaaatgtta ccgcatccga
    27781 ttaatatggt aagggttaga ctttctggtg tgaaattaaa agagattata actaaaagta
    27841 ataaacaaga atatatgtat gaacatgcac aaggtttggg tttcagaggg aatatatttg
    27901 gaggatatat tctttataat ttagggtaca ttcattctac agggcgttac tatctgaatg
    27961 gagaagaaat cgaagacgac aaagaatatg tattaggtac gatagacatg tatacgttcg
    28021 gtcgttattt cccaacactg aaagaattac caaaagagta tttaatgcca gagtttttaa
    28081 gagatatatt taaagaaaaa ttattggaat attaaaaagt aagattattg gattttcatt
    28141 tgtcatgaat ttcgatataa tgtttaaaga tacacttaac aggagggtat gtgttgttat
    28201 ggcgacaaaa aacgaggaaa tattacgtaa accggattgg ttgaaaataa aattaaatac
    28261 caacgaaaac tatacaggac ttaagaagat gatgagggaa aaaaatctta atactgtatg
    28321 tgaagaagct aaatgtccta atatacatga atgttggggt gcacgtcgta cagcgacatt
    28381 tatgatttta ggtgccgtat gtacaagagc ttgtcgtttt tgtgcggtta agacaggttt
    28441 acctaatgaa cttgatttaa atgagcctga acgtgtagct gaatcagttg aattaatgaa
    28501 tttgaaacac gttgttatca ctgctgttgc gcgtgatgat ttaagagatg ctggttcaaa
    28561 tgtttatgct gagacagtac gtaaagttag agaaagaaat ccatttacaa cgattgaaat
    28621 tttaccatca gatatgggcg gggactatga tgcgttagaa acattaatgg cgtcaagacc
    28681 tgacatttta aaccataata ttgaaactgt tcgtcgctta acaccgagag ttcgtgcgcg
    28741 tgcgacttac gacagaacat tagagttttt acgtcgttca aaagaattac aaccagatat
    28801 cccaactaaa tcaagtatta tggttggatt aggtgaaact atagaagaaa tttatgaaac
    28861 gatggatgat ttacgtgcga atgatgtaga tattttaacg attggtcaat atttacaacc
    28921 ttcacgtaaa catttaaagg ttcaaaaata ttacacgcct ttagagtttg gtaaattaag
    28981 aaaagtggca atggataaag ggtttaaaca ttgccaagct ggacctttag tacgtagttc
    29041 ttatcatgcg gatgagcaag taaatgaagc tgctaaagaa aagcaacgcc aaggtgaggc
    29101 acagttaaat agttaatatt taacaattaa taaggcataa aggcttagtt tgtacaaaac
    29161 gaacgtgtca tagaagtaat cattattttt atgaaacact aaaagtataa actgagcctt
    29221 tcattgtcat agataggtga agaatttgat aaaagtagat caacattact ttgaattaat
    29281 agaaaattat cgcgaatgtt ttaatgaaga acaatttatt gctaggtatt cagatatttt
    29341 agacaaatat gattacattg ttggtgacta tggttacgat caattacgat taaaaggctt
    29401 ttacaaagat tctaataaaa aagcagagat gagtaaacgt ttttcaaata ttcaagatta
    29461 catatttgaa tattgtaact ttggttgtcc ttactttgta ttaagacatt tgtctaaaca
    29521 agaggttaaa aagttaatcg aagaagttca tccgtctgat gtgatagatg acgacaataa
    29581 acttcaagat gtgaagatta agccaaccat tcaagatact gaacattaat aaaaccctta
    29641 gctagattga aaatgggaat catgcaattc aagcatggac ctgtaatcta gttaggggtt
    29701 tttatcttta atga
//
LOCUS       DAPDIM010000035        28791 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000035 DAPDIM010000000
VERSION     DAPDIM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 28791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28791
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.035"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..396)
                     /locus_tag="RFE25_001577"
     CDS             complement(<1..396)
                     /locus_tag="RFE25_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HDU2816636.1"
                     /translation="MSEKQSNEQVEAFLNKESQWQEEYKYLRALIFNETELEEAYKWM
                     HPCYTLNNKNVVLIHGFKNYVALLFHKGAILEDKYHTLIQQTEKVQAARQLRFENLTE
                     IQARTEEIKYYLAEAIKAEKAGKKVEMKKT"
     gene            576..2213
                     /locus_tag="RFE25_001578"
     CDS             576..2213
                     /locus_tag="RFE25_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDU2816637.1"
                     /translation="MNKDKQLHNDKINLSQLVLLGLGSLIGSGWLFGAWEASSIAGPV
                     AIISWVLGFLVIGTIAYNYIEIGTMFPQSGGMSNYAQYTHGSLLGFIAAWANWVSLVT
                     IIPIEAVSAVQYMSSWPWHWAKPMRYLMENGSISTYGLLAVYLIIVIFSLLNYWSVKL
                     LTSFTSLISVFKLGVPMLTIIMLMLSGFDTSNYGHSASTFMPYGSAPIFAATTASGII
                     FSFNSFQTIINMGSEIKNPEKNIARGIAISLSISAVLYIILQSTFITSMPQSMLQHSG
                     WNGINFNSPFADLAILLGINWLAILLYIEAFVSPFGTGVSFVAVTGRVLRAMEKNGHI
                     PKFLGKMNEKYHIPRVAIIFNAIISMIMVTLFRDWGTLAAVISTATLVAYLTGPTTVI
                     ALRKMGPTMTRPFRAKILKVMAPLSFVLASLAIYWAMWPTTAEVILIIILGLPIYFFY
                     EYRMNWRNTKKQIGGSLWIIVYLIVLSILSFIGSKEFKGLNMIHYPFDFIVIIVVALI
                     FYYIGTTSSFESVYFRRATRINTKMRESLNNESKSSH"
     gene            2522..3874
                     /locus_tag="RFE25_001579"
     CDS             2522..3874
                     /locus_tag="RFE25_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="HDU2816638.1"
                     /translation="MKINTTGGQIHGITQDGLDIFLGIPYAEPPVHDNRFKHSTLKTQ
                     WSEPIDATEIQPIPPQPDNKLEDFFSSQSTTFTEHEDCLYLNIWKQHNDQTKKPVIIY
                     FYGGSFENGHGTAELYQPAHLVQNNDIIVITCNYRLGALGYLDWSYFNKDFHSNNGLS
                     DQINVIKWVHQFIESFGGDANNITLMGQSAGSMSILTLLKIPDIEPYFHKVVLLSGAL
                     RLDTLKSARNKAQYFQKMMRDYLDTDDVTSLSTDDILMLMAKLKQSRGPSKGLDLIYA
                     PIKTDYIQNDYPTTKPIFACYTKDEGDIYITSEQKKLSPQRFIDIMELNDIPLKYEDV
                     QTAKQQSLAITHCYFKQPMKQFLQHLNIQDSNAQLWLAEFAWHDTSSAHYRSAYHILD
                     MVFWFGNLQILAAHQYPTTAHLKFLSRQMQNDLANFAKSGKMPWPMYHNERRYYRTYQ
                     "
     gene            complement(3936..5123)
                     /locus_tag="RFE25_001580"
     CDS             complement(3936..5123)
                     /locus_tag="RFE25_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2816639.1"
                     /translation="MSIMRLFTFILSIFIVGMVEMMVAGIMNLMSQDLHVSEAVVGQL
                     VTMYALTFAICGPILVKLTNRFSSRPVLLWTLLIFIIGNGIIAVAPNFSILVVGRIIS
                     SAAAALIIVKVLAITAMLSAPKNRGKMIGLVYTGFSGANVFGVPIGTVIGDLVGWRYT
                     FLFLIIVSIIVGFLMMIYLPKDQEIQRGPVNHEAPSHENHVTSKILRPAEVAKYLIIT
                     FLVLIANSVTFVFINPLILSNGHDMSFVSLALLVNGIAGVIGTSLGGIFSDKITSKRW
                     LMISVSIFIVMMLLMNLILPGSGLLLAGLFIWNIMQWSTNPAVQSGVIQHVEGDTSQV
                     MSWNMSSLNAGIGVGGIIGGLVMTHVSVQAITYTSAIIGALGLIVVFTLKNNHYAKTF
                     KSS"
     gene            complement(5519..6295)
                     /gene="fetB"
                     /locus_tag="RFE25_001581"
     CDS             complement(5519..6295)
                     /gene="fetB"
                     /locus_tag="RFE25_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HDU2816640.1"
                     /translation="MSNTALGLTALLLVIPIIISYKEGLHIIKDLIVATLRAAVQLII
                     LGFLLHYIFKINDKWLLILCVLVIIINASWNTISRASPVMHHVFWISFLAIFIGTALP
                     LAGTVATGAIHFTANEVIPIGGMLANNGLIAINLAYQNLDRAFVQDGTNIESKLSLAA
                     TPKLASKGAIRESIRLAIVPTIDSVKTYGLVSIPGMMTGLIIGGVPPLQAIKFQLLVV
                     FIHTTATIMSALIATYLSYGQFFNARHQLVARNTDVKSES"
     gene            complement(6288..6950)
                     /locus_tag="RFE25_001582"
     CDS             complement(6288..6950)
                     /locus_tag="RFE25_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDU2816641.1"
                     /translation="MLLEIKDLVYKASDRIILDHISLKVDKGESIAIIGPSGSGKSTF
                     QKQICNLISPTSGELYFKGKPYNDYDPEELRQRISYLMQQSDLFGETIEDNMIFPSLA
                     RNDKFDRKRAKQLIKDVGLGHYQLSSEVENMSGGERQRIAIARQLMYTPDILLLDEST
                     SALDVNNKEKIENIIFKLVEQDVAIMWITHSDDQSMRHFQKRITIVDGKISKVEELNQ
                     HE"
     gene            complement(7198..8274)
                     /locus_tag="RFE25_001583"
     CDS             complement(7198..8274)
                     /locus_tag="RFE25_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDU2816642.1"
                     /translation="MNQSVKLLKHLTDVNGIAGYEMQVKEAMRNYIEPVSDQIIEDNL
                     GGIFGKKNAENGQYSIMISGHMDEVGFMVTKIDKHGFISFTPVGGWWNQVMLSQKVTI
                     TTDSGKEIRGIIGSKPPHVLTPEERKKPMEIKNMFIDIGVSSKEEAEEAGVEVGNMVT
                     PYSEFEVLANDKYLTAKAFDNRYGCALAVEVLKRLKDENIGINLYSGATVQEEVGLRG
                     AKVAANTIKPDLAIAVDVGIAYDTPGMSGQTSDSKLGGGPVVIMMDATSIAHQGLRKH
                     IKDVAKEHNIEVQWDTIPGGGTDAGSIHVANEGIPTMTIGVTLRYMHSNVSVLNVDDY
                     ENSIRLVTEIVRSLNDESYKNIMW"
     gene            complement(8629..8895)
                     /locus_tag="RFE25_001584"
     CDS             complement(8629..8895)
                     /locus_tag="RFE25_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDU2816643.1"
                     /translation="MSNYTVKIKNSAKSDLRKIKHSYLKKSFLEIVETLKNDPYKITQ
                     SFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLILSAWSHYD"
     gene            complement(8895..9152)
                     /locus_tag="RFE25_001585"
     CDS             complement(8895..9152)
                     /locus_tag="RFE25_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDU2816644.1"
                     /translation="MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLE
                     DWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDIDWDNL"
     gene            9511..9966
                     /locus_tag="RFE25_001586"
     CDS             9511..9966
                     /locus_tag="RFE25_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1307 domain-containing protein"
                     /protein_id="HDU2816645.1"
                     /translation="MKKLCSLIVVALICIIALSACGKEQTKTYEGDVSGKHVLTSITY
                     KDDKVLKQSTINTIKYDDLGMDKDEAKKLFAKSESIFKDLKGVKYKVDYKDKKAIEHL
                     DIDYTEVDMKKLNKRLGVSTKENKDISFEKLEKQLKHRGLKEKDKMDDK"
     gene            complement(10134..11711)
                     /locus_tag="RFE25_001587"
     CDS             complement(10134..11711)
                     /locus_tag="RFE25_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="HDU2816646.1"
                     /translation="MTFLTVMQFIVNIIVVGFLLTVIVIGLIWLIKDKRQSQHSVLRN
                     YPLLARIRYISEKMGPELRQYLFSGDNEGKPFSRNDYKNIVLAGKYNSRMTSFGTTKD
                     YQDGFYIQNTMFPMQRNEISVDNTTLLSTFIYKIANERLFSREEYRVPTKIDPYYLSD
                     DHAIKLGEHLKHPFILKRIVGQSGMSYGALGKNAITALSKGLAKAGTWMNTGEGGLSE
                     YHLKGNGDIIFQIGPGLFGVRDKEGNFSEGLFKEVAQLSNVRAFELKLAQGAKTRGGH
                     MEAEKVNEEIAKIRNVEPYKTINSPNRYEFIHNAEDLIRFVDQLQQLGQKPVGFKIVV
                     SKVSEIETLVRTMVELDKYPSFITIDGGEGGTGATFQELQDGVGLPLFTALPIVSGML
                     EKYGIRDKVKLAASGKLVTPDKIAIALGLGADFVNIARGMMISVGCIMSQQCHMNTCP
                     VGVATTDAKKEKALIVGEKQYRVTNYVTSLHEGLFNIAAAVGVSSPTEITADHIVYRK
                     VDGELQTIHDYKLKLIS"
     gene            11907..12656
                     /locus_tag="RFE25_001588"
     CDS             11907..12656
                     /locus_tag="RFE25_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDU2816647.1"
                     /translation="MSNTNKHYIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVF
                     LTFGLVAVFTQQAPWGFSFPISMNISYLLAVIISLAIFRRMHEDAFVPMIRTQIIAST
                     KYKWHILISFTLSVVLFLLLNYFDIFALNVDAFTVFDIYPLIRDYDSISLIVMLWLTI
                     ILNTLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILAS
                     SATYLYLKSNRNFMVSYFYQLAVILVLHIFM"
     gene            complement(13018..14211)
                     /locus_tag="RFE25_001589"
     CDS             complement(13018..14211)
                     /locus_tag="RFE25_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2816648.1"
                     /translation="MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVI
                     GIVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARV
                     MQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNIS
                     LFAIVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAVTVFAQFFKNKELLNSGI
                     IMIVASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVAARFYLRKYIPSDGMWHP
                     KYMVSVLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVG
                     RNMLLGLFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSFLKKPTPR
                     PASSL"
     gene            complement(14223..14972)
                     /locus_tag="RFE25_001590"
     CDS             complement(14223..14972)
                     /locus_tag="RFE25_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816649.1"
                     /translation="MIKVTDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGES
                     GSGKSTLSRMILGIEKPDKGCVTLNDLPMHKKKVRRHQIGAVFQDYTSSLHPFQTVRE
                     ILFEVMCQCDGQPKEVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICI
                     NPKYILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFK
                     NGKIEEQIPTSALHKSDNAYTRELIEKQLSF"
     gene            complement(14965..15780)
                     /locus_tag="RFE25_001591"
     CDS             complement(14965..15780)
                     /locus_tag="RFE25_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816650.1"
                     /translation="MTLLTVKHLTITDTWTDQPLVSDVNFTLTKGETLGVIGESGSGK
                     SITCKSIIGLNPERLGVTGEIIFDGTSMLSLSESQRKKYRGKDIAMVMQQGSRAFDPS
                     TTVGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLM
                     IALALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIA
                     DRVVVMKNGQLIEHGTRESVLHHPEHVYTKYLLSTKKKINDHFKHVMRGDVHD"
     gene            complement(15777..16646)
                     /locus_tag="RFE25_001592"
     CDS             complement(15777..16646)
                     /locus_tag="RFE25_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2816651.1"
                     /translation="MIILKRLLQDKGAVIALGIIVLYVFLGLAAPLVTFYDPNHIDTA
                     NKFAGISFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQ
                     GFVDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVM
                     QYTASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLG
                     VKAPTAEWGMMLNEARKVMFTHPEMMFAPGIAIVIIVMAFNFLSDALQIAIDPRISSK
                     DKLRSVKKGVVQS"
     gene            complement(16643..17578)
                     /locus_tag="RFE25_001593"
     CDS             complement(16643..17578)
                     /locus_tag="RFE25_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2816652.1"
                     /translation="MFKFILKRIALMFPLVIVVSFMTFLLTYITNENPAVTILHAQGT
                     PNVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNT
                     LKLTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVS
                     VKLNILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVK
                     SITLMLHVLRNAIQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPV
                     IQAYVLIVAVLFIVFNTLADIINALLNPRLREGAR"
     gene            complement(17591..19189)
                     /gene="cntA"
                     /locus_tag="RFE25_001594"
     CDS             complement(17591..19189)
                     /gene="cntA"
                     /locus_tag="RFE25_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylopine-dependent metal ABC transporter
                     substrate-binding protein CntA"
                     /protein_id="HDU2816653.1"
                     /translation="MRKLTKMSAMLFASGLILTGCGGNKGLEEKKENKQLTYTTVKDI
                     GDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLAKKWDVSEDGKTYTFHLRDDVKFH
                     DGTTFDADAVKKNIDAVQQNKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAE
                     LAMPRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSK
                     LNKVQAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQP
                     MNTKMLVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDI
                     NFDMPTRKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEY
                     LQAEFKKMGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGY
                     ESATSGIENKDKIYNSIDDAFKIQNGKERSDAYKNILKQIDDEGIFIPISHGSMTVVA
                     PKDLEKVSFTQSQYELPFNEMQYK"
     gene            complement(19332..20633)
                     /gene="cntM"
                     /locus_tag="RFE25_001595"
     CDS             complement(19332..20633)
                     /gene="cntM"
                     /locus_tag="RFE25_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_096659686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylopine dehydrogenase CntM"
                     /protein_id="HDU2816654.1"
                     /translation="MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLY
                     QAYKKEKQFEVKIQNEAHQHLEGKFEINRLYKDVKNVKGEYETVVMACTADAYYDTLQ
                     QLSLETLQSVKHVILISPTFGSQMIVEQFMSKFSQDIEVISFSTYLGDTRIVDKEAPN
                     HVLTTGVKKKLYMGSTHSNSTMCQRISALAEQLKIQLEVVESPLHAETRNSSLYVHPP
                     LFMNDFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQAFRVPSVN
                     LLQFMVKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYTAILIDPFSQPDENGHY
                     FDFSAVPFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIKTPMIDQFLTRYEA
                     SCQAYKDMHQDQQLSSQFNTNLFEGDKALVTKFLEINRTLS"
     gene            complement(20626..21444)
                     /gene="cntL"
                     /locus_tag="RFE25_001596"
     CDS             complement(20626..21444)
                     /gene="cntL"
                     /locus_tag="RFE25_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-histidine (S)-2-aminobutanoyltransferase CntL"
                     /protein_id="HDU2816655.1"
                     /translation="MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYS
                     EFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYF
                     DNIEHCIDEEFGQCSITSNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLG
                     RRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVV
                     AMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV"
     gene            complement(21455..22276)
                     /gene="cntK"
                     /locus_tag="RFE25_001597"
     CDS             complement(21455..22276)
                     /gene="cntK"
                     /locus_tag="RFE25_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine racemase CntK"
                     /protein_id="HDU2816656.1"
                     /translation="MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVC
                     CEQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCS
                     DLVQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKALEIIYETYVHYVIPVKQVTTE
                     IQHLVEAFVREQQWSHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASI
                     GVFNNYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE"
     gene            complement(22966..23733)
                     /locus_tag="RFE25_001598"
     CDS             complement(22966..23733)
                     /locus_tag="RFE25_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001599343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDU2816657.1"
                     /translation="MNIRHIRNATAVIEYGGKRILIDPMLSDKGSFDPFPNSPRQDQK
                     NPLVELPMAIEDIINDIDLVILTHLHIDHFDPKAIEVLPKDIKIYAQNEEDASEVERY
                     GFTNVSVFNDVTHIGEIELIKTDAQHGHGEILKMTGHVHGMILKHSEEPTLYLAADTV
                     WFEGVEKALKTYQPDVVVLNGGANQFFEGGPLVMDEHDVLKVANTLPLAQIVVVHMEA
                     VNHWHLSRKELNEFINSNDLGNRVVVPNDGELLTFEK"
     gene            complement(23821..24639)
                     /locus_tag="RFE25_001599"
     CDS             complement(23821..24639)
                     /locus_tag="RFE25_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001620216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDU2816658.1"
                     /translation="MKRLENKVAVVTGASTGIGQASAIALAQEGAYVLAVDIAEAVSE
                     TVDKIKSNGDNAKAYNVDISDEQQVVDFVSDIKEQFGRIDVLFNNAGVDNAAGRIHEY
                     PIDVYDKIMNVDMRGTILMTKMMLPLMMNQGGSIVNTSSFSGQAEDLYRSGYNAAKGA
                     VINFTKSIAIEYGRDGIRSNAIAPGTIETPLVDKLTGTSEDDAGKTFRENQKWMTPLG
                     RLGKPEEVAKLVVFLASDDSSFITGETIRIDGGVMAYTWPGEMLSDDSWKRTLE"
     gene            24874..26412
                     /locus_tag="RFE25_001600"
     CDS             24874..26412
                     /locus_tag="RFE25_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDU2816659.1"
                     /translation="MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMT
                     WVISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIG
                     VAEKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIG
                     YHPIAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIA
                     ASVVVLLPTILLVTTKLIIPRLGKYDDSLMHDDHEEASSHITDKEAHALKWANISFIV
                     TIILLIITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKN
                     TKDLGKMFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLI
                     LGIIVLSAMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITP
                     MMPYLPLLLTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGP
                     IFVK"
     gene            complement(26525..26947)
                     /locus_tag="RFE25_001601"
     CDS             complement(26525..26947)
                     /locus_tag="RFE25_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDU2816660.1"
                     /translation="MPYNYKKQNGELMSVMSQGEKFIHQSPVNDELSALIKLLISKIN
                     GCHYCVDIHKKELKELGVTQMKIDEVLSFRHLDLFTDQEKVTLEFAEMLNSIKDFKKF
                     EIIDRLKSFYDEEQIIDLVFVVNQINGWNRLNIISDRL"
     gene            complement(27399..27818)
                     /locus_tag="RFE25_001602"
     CDS             complement(27399..27818)
                     /locus_tag="RFE25_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDU2816661.1"
                     /translation="MNKKHVFVIIGVILCICIVASVIYLKVKYDEKEKQKAIYYKEQQ
                     ERITLYLQHNTKEPNTIKSVHFTSLKRGPMGDAVIEGYINENKKDNFTAYATPEHNYQ
                     FGGAMIESERLSELLKPAHQLKSPDEIKEELDKKEGH"
     gene            complement(27845..28255)
                     /locus_tag="RFE25_001603"
     CDS             complement(27845..28255)
                     /locus_tag="RFE25_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDU2816662.1"
                     /translation="MSKKKILILTSIMLIILISVASIYFKMKYDEKEKQKSIYYKEQQ
                     ARITLYLKHNTIEPNTIKSVHFTKLETSPMGSAVIEGYINENKEDDFVAYASPENNFQ
                     FVGDLIKSERLSELLKPAHQLKSPDDIKKELNKK"
     gene            complement(28522..>28791)
                     /locus_tag="RFE25_001604"
     CDS             complement(28522..>28791)
                     /locus_tag="RFE25_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDU2816663.1"
                     /translation="NHNTKEPNTIKTVHFTSLKRGPMGDAVIEGYINENKEDDFVAYG
                     SPEHNYQFGGSLIKSKNLSTLLKPVHQTKSPDEIKKELESKKNDR"
BASE COUNT         9140 a         5484 c         4280 g         9887 t
ORIGIN      
        1 tgttttcttc atttcaactt ttttaccagc tttttcagct ttaattgctt cggctagata
       61 atatttaatt tcttcggtac gtgcttgaat ctctgttaaa ttttcaaatc gtaactgacg
      121 agctgcttgc accttttcag tctgttgaat gagtgtatga tatttatcct ccaaaatggc
      181 acctttatga aataatagtg caacataatt tttgaagcca tggataagta ctacattttt
      241 attattcaac gtgtaacaag gatgcatcca tttatacgct tcctctaatt ctgtttcatt
      301 aaagattaac gctctcaaat atttatattc ttcttgccat tgactctctt tatttaaaaa
      361 tgcttcaact tgttcatttg attgtttctc actcatagtc atcacttcca ttttgttttt
      421 caatacacat tgtattatat atcctaattt tataaaaaac taattttaca aatgcttttg
      481 cgttcttaca aaaaatgcat ttgactatta ttataataag cgtataattg tcgcatatta
      541 ttttttgtat ttttggcaat aacgaaggag tatttatgaa taaagacaag caattgcaca
      601 acgacaaaat caatctatcc caattagtct tattagggtt aggctcttta ataggatctg
      661 gttggctatt tggtgcgtgg gaagcatcat caatagctgg accagtagca atcatatcat
      721 gggttcttgg attcctagtc attggaacca ttgcctataa ctacattgaa atcggcacaa
      781 tgtttcctca atcaggtggc atgagtaact atgcccagta tacacatggc tcattattag
      841 gctttattgc tgcttgggcg aattgggtgt ctttggtgac aataatacct atcgaagctg
      901 tgtcagctgt tcaatatatg agttcttggc cgtggcattg ggcgaaacca atgagatatt
      961 taatggaaaa tggctctatt agcacatacg gattgctagc tgtatatctc atcattgtta
     1021 ttttttcatt attaaactat tggtccgtaa aacttttaac atcatttacg agtttaattt
     1081 ctgtatttaa attaggcgta cccatgttaa ccatcatcat gttgatgtta tcaggattcg
     1141 acacttcaaa ttacggccat tcggcaagca catttatgcc ttacggaagt gcaccgattt
     1201 ttgctgcaac aacagcatca gggattattt tttcattcaa ttcattccag acaattatta
     1261 atatgggttc agaaattaaa aatcctgaaa aaaatatcgc aagaggcatc gctatttcac
     1321 tgtcaatcag tgcagtgttg tacatcattt tacaaagtac gtttatcact tctatgcctc
     1381 aatcaatgtt acaacatagt ggatggaatg gcatcaactt caattcacca tttgcagatt
     1441 tagctatctt attaggaatt aattggctcg caattttact atatattgaa gcttttgtat
     1501 caccattcgg tactggcgtg tcatttgtcg ccgttacagg tcgagtttta cgagcaatgg
     1561 agaaaaatgg acatatccct aaatttcttg ggaagatgaa tgaaaaatat catatcccac
     1621 gtgtagcaat catctttaat gccatcatta gtatgattat ggttacatta tttagagatt
     1681 ggggtacgct agcagcagtt atttctactg caactttagt agcctattta actggcccaa
     1741 cgacagtgat tgcattaaga aaaatgggac caacaatgac tcgtccattt agagcaaaaa
     1801 ttttaaaagt aatggcacca ttatcatttg tattagcttc attagctata tattgggcaa
     1861 tgtggccaac aacggctgaa gttattttaa tcattatact tggattacca atctacttct
     1921 tctatgaata ccgtatgaat tggcgtaata caaagaaaca aattggtggt agcttatgga
     1981 ttattgtata tttaatcgtg ctatcaatac tgtcatttat aggaagcaaa gaatttaaag
     2041 gcttaaatat gattcactat ccatttgact ttatcgttat tattgttgtg gcgcttatat
     2101 tctattacat cggtacaacg agttcatttg aaagcgtcta tttccgtcgc gcaacacgaa
     2161 tcaatacaaa gatgcgcgag tcactaaata atgaatcaaa gtcatctcat taaatatttt
     2221 aaaatgcaat gccatatatg atttcaacac acacacatta accaaccatt gatttcaaca
     2281 tcttggttgg ttttttattt tgaaaatcgg ttataaataa ctaacataac aatgtggcga
     2341 gagtgatatt gtaatgaaat gtcactgtag aagaacatca tataatgctg aaaatggttt
     2401 gagttaaaac agatatcaag ctagtctgat tcagtcacaa aattgtcttg ttatacttgt
     2461 cacctatcat ctatagaccg tggtatgatt aaattgggga tgataaagga ggttaataaa
     2521 tatgaagatt aatactacag gtggtcaaat tcatggtatt acacaagatg gtttagatat
     2581 cttcttaggc attccttatg cagaaccacc agttcatgat aatcgcttta aacattctac
     2641 gttaaaaaca caatggtcag agccaattga tgcaactgaa atacaaccca tcccaccgca
     2701 accagacaac aaattagaag attttttctc ctcacaatct acaactttta ctgaacatga
     2761 agactgttta tatctaaata tttggaaaca acataatgat cagacgaaga aacctgtcat
     2821 catttatttt tatggtggta gttttgaaaa tggtcatggt acagccgaac tctatcaacc
     2881 ggcacattta gtacaaaata acgacattat cgttattaca tgcaattatc gtttaggcgc
     2941 attaggatat ttagactggt catattttaa taaagatttt cattccaata atggactttc
     3001 agatcaaatc aatgtcataa aatgggtgca tcaatttatt gaatcctttg gtggcgacgc
     3061 taataacatt actttaatgg gtcagtctgc aggcagtatg agcattttga ctttacttaa
     3121 aatacctgac attgagccat acttccataa agtcgttcta ctaagtggcg cactacgatt
     3181 agacaccctt aagagtgcac gcaataaagc acaatatttc caaaaaatga tgcgcgatta
     3241 tttagataca gatgatgtta catcattatc gacagatgat attcttatgc tgatggcgaa
     3301 gctaaaacaa tctcgaggac cttctaaagg gcttgattta atatatgcgc ctattaaaac
     3361 agattatata caaaatgatt atccaacaac gaaaccaatt tttgcatgtt atacaaaaga
     3421 tgaaggcgat atttatatta ctagtgaaca gaaaaaatta tcgccgcaac gctttatcga
     3481 cattatggaa ttaaatgata ttcctttaaa atacgaagat gttcagactg cgaagcaaca
     3541 atctttagcg attacacatt gttatttcaa acagccgatg aagcaatttt tacaacatct
     3601 taatatacaa gattcaaacg cacaactatg gcttgctgaa tttgcatggc atgatacttc
     3661 tagcgcacac tatcgcagtg cttaccatat tctagatatg gtattttggt tcggaaactt
     3721 acaaatatta gcagcacatc aatatccaac aactgctcac cttaaatttt taagtcgaca
     3781 aatgcaaaat gatttagcta attttgctaa aagcggtaaa atgccttggc cgatgtatca
     3841 taatgaacgt cgctattatc gcacatatca ataacgttat cgcatctaaa aaagcacacc
     3901 tgaatttgat agcaggcgtg cttttcatat gagaattatg atgatttaaa tgttttagca
     3961 taatgattat ttttcaatgt gaaaacaacg attaatccta atgcgccaat gatggcactc
     4021 gtatatgtga tagcttgaac agaaacatgt gtcatgacca agcctccaat aatgccgcca
     4081 acaccaatac cagcgtttaa actagacatg ttccaactca ttacttggct tgtgtcgcct
     4141 tcaacatgtt gaatcacacc gctttgcact gctggattag tactccattg catgatattc
     4201 caaataaata gtcctgctaa caatagacct gaaccaggta agattaaatt cataagtaac
     4261 atcataacga taaaaataga aacagaaatc attaaccaac gcttacttgt aattttatcg
     4321 gagaatatac cacccaatga tgttccaata acgccagcga ttccatttac tagaagtgct
     4381 aatgaaacga atgacatatc atgaccatta gataaaataa gtggatttat aaagacgaat
     4441 gtcactgagt ttgcaatcaa tactaaaaac gtaataatta aatattttgc tacttcagca
     4501 ggtcttaata ttttcgaagt aacatgattt tcatgagatg gtgcctcatg attcacaggg
     4561 cctcgttgta tttcctgatc cttcggtaaa tagatcatca tcaagaagcc aacaataata
     4621 ctcacaataa ttaagaatag aaatgtatag cgccaaccta ctaaatcgcc gataaccgtt
     4681 ccaattggta caccaaaaac attggcccca ctaaaccctg tatagacaag tccaatcatt
     4741 ttgccacgat ttttaggtgc tgataacatc gctgtaatag ctaatacttt tacgataatt
     4801 agtgctgctg ctgcagatga gataattcta ccaactacta atattgaaaa atttggcgct
     4861 acagcaataa tgccattacc aatgataaat ataagtaatg tccataataa tacaggcctt
     4921 gatgaaaaac ggttcgttaa tttaaccaga ataggtccac atatcgcaaa tgttaaagcg
     4981 tacattgtca ctaattgacc aacgacagct tctgatacat gtaagtcctg actcatcaag
     5041 ttcataattc ctgcaaccat catttcaacc attcctacga taaaaatact taaaatgaat
     5101 gtaaatagtc gcatgattga cattttaaaa ctcctttcaa acaaaatttc cgatattcat
     5161 ttcccttaga ataacgattt attaaaaaat gtgtgcaaca caattttata tataaccgtt
     5221 ctattatata atattttgct ttaattttct gtgcttaaat ggaaaattat tgaaattgtt
     5281 tttcagtatt tgaaaaatta acacaagtat gtcatttaat aattatgtat aattacttca
     5341 gtttcaacaa tgtcttcaaa aaagcacgca cgctttatat gtcagaacag ataactgact
     5401 acaaagtatg cgtgccttta tgaatatttt cgctgtgtta atgaatagcg atactatatg
     5461 tgcgcgtcac ttcatttcca attaaaacta atgcctaaat ctgatgcagt aaaatctatc
     5521 atgattcact cttaacatcc gtatttcgtg ctactaattg atgtcttgca ttgaaaaatt
     5581 gaccatagct taaatatgtc gcaatcaaag cagacataat ggtcgcagtt gtatgaataa
     5641 acacgactaa caattgaaat ttaatcgctt gtaaaggtgg tacgccacca ataattaagc
     5701 ctgtcatcat accaggaatc gacacaagcc catatgtttt aaccgaatca attgttggca
     5761 ctatagctaa acgaatactt tcacgtattg cacctttaga agccaattta ggtgtagctg
     5821 caagtgataa tttagattca atattagtac catcttgtac gaatgcacga tctaaattct
     5881 ggtaagctaa attaattgca atcaagccat tatttgcaag catgccgccg ataggtataa
     5941 cttcattggc tgtaaaatga attgcccctg tagctacagt acctgcaagt ggtaatgctg
     6001 ttccaatgaa gatagctaga aatgatatcc aaaacacatg atgcatcact ggtgatgctc
     6061 gactaattgt attccatgat gcattaataa taatgaccaa tacacataaa ataagcagcc
     6121 atttatcgtt tattttaaaa atataatgca gcaaaaatcc caaaatgatt aattgcaccg
     6181 ctgcgcgtag tgtcgcaaca attaaatctt taataatatg taaaccttct ttatatgaaa
     6241 tgataatcgg aatgactaaa agcaatgccg tcaatccaag tgccgtatta ctcatgttga
     6301 ttcaactcct caaccttaga aattttgcca tcaacaatcg ttatgcgctt ttgaaaatgt
     6361 ctcatacttt gatcatcact atgggtaatc cacatgatag caacatcctg ttccactaac
     6421 ttaaaaatga tattttctat cttttcttta ttattaacgt ctaatgcact ggtcgattca
     6481 tctaataaaa gaatatccgg tgtatacatc agttggcgcg ctatagcaat tctttgccgc
     6541 tcaccacccg acatattttc cacttccgaa cttaattgat aatgtcccaa accgacatct
     6601 ttaattaatt gctttgcacg ttttctatca aatttatcat tacgtgcaag tgatgggaat
     6661 atcatgttat cttcaatcgt ttcaccaaac aagtcacttt gctgcatcaa ataactgatt
     6721 cgttgacgca attcttccgg gtcataatca ttatagggtt tacctttaaa ataaagttct
     6781 ccactagttg gactaatcaa attacatatt tgcttttgaa atgtactttt accactacct
     6841 gatggaccta taatggcaat actctcgcct ttatctactt ttagactgat atgatctagt
     6901 atgattctat cgctcgcttt atacactaaa tctttaattt ctaacaacat ttgcaccgct
     6961 cctcatgtaa tatatcaggt atattattcc cgtttttttg gtttttagtg caattacatt
     7021 taagaaaaaa tcattttctt gtaatatcaa aatttaggca taattgattt tcagcattta
     7081 aattaaaaac aaaaaatcct attaacatgg atactgtcta atgactaaga attaaagtta
     7141 gacaattgtt taacaaccta ccatattaaa aggattcttt attatttatg gatttgatta
     7201 ccacatgata tttttataac tttcatcatt caatgaacgg acaatttcag taacaagacg
     7261 gatagaattt tcataatcat ctacattgag cactgaaaca ttagaatgca tgtatcgcag
     7321 cgtaacaccg attgtcatcg ttggaatacc ttcatttgcg acatgaatac ttcccgcatc
     7381 tgtacctcca cctggtatcg tatcccattg tacttcgatg ttatgttcct tagctacatc
     7441 tttaatatgc ttacgcaaac cttggtgagc aatacttgta gcatccatca taatgacaac
     7501 tggaccaccg cctagtttac tatcgctcgt ttgacctgac atacctgggg tatcataagc
     7561 aatacctaca tcgacagcta tcgccaaatc tggtttaatt gtattcgctg ccactttcgc
     7621 accacgcaaa ccaacttctt cttgcactgt ggcaccactg tataagttaa ttccaatatt
     7681 ttcatctttt aaacgtttta atacctcaac agctaatgca cagccatagc gattatcaaa
     7741 tgctttcgca gttaaatatt tatcatttgc aagcacttca aattcactat atggcgttac
     7801 catattgcct acttcaacgc cagcttcttc agcttcttcc ttgctactaa caccaatatc
     7861 tataaacata tttttgattt ccattggctt tttacgttct tcaggcgtta agacatgtgg
     7921 cggtttagaa ccgatgatac ctctaatttc tttgcccgaa tctgttgtaa tcgttacttt
     7981 ttgagatagc atgacttgat tccaccatcc accaactggc gtaaatgaaa taaaaccatg
     8041 tttatcaatc tttgttacca taaaaccaac ttcatccata tgaccagaaa tcataattga
     8101 gtattgacca ttctcagcat ttttctttcc aaaaatgcca cccaagttat cttcaataat
     8161 ttgatcactg acaggctcta tatagttacg cattgcttct ttaacttgca tttcataacc
     8221 agcaatgccg tttacatctg ttaaatgttt aagtaatttg actgactgat tcatgttatt
     8281 catcctcctg tatttcaact taaaactatt gtatcactaa ctttcagaaa aacgttccct
     8341 accgctttat cattttcagg cttaaatttt ttaaaatttt gtgagaaatc cgcttcaaaa
     8401 acctcatatt tttaaaattt aatattccga aaaagtcaca atttaaaatt ccttattata
     8461 atatgttatt cttttattgt tactaatttc aatttgttta gtcttgcgct attataaaat
     8521 taaaaagtgt agagataaca acgcattaac gtcgctattt tccctacact taaatactag
     8581 tttctttaat taacttacca ttaaagttat tcagatattg aatattcatt aatcataatg
     8641 tgaccatgcc gatagtatta atacttcttt atttcgatca tctacggtat agacgaccct
     8701 gtgctgatgg ttaattcttc ttgaatatcg ctctaaatat ttaggctcta atttttcaaa
     8761 agattgtgtt attttatacg gatcattttt taaagtctca acaatttcta aaaatgactt
     8821 ctttaaataa gaatgtttta ttttccttaa atctgatttc gctgaatttt taatcttaac
     8881 cgtgtaattg ctcattaaag attatcccaa tcaatatcat ctatatttgt tgtaccacta
     8941 ttatcttttt ctctttctct tactttgtcc attgtaccag tagattcaag atatattgtc
     9001 tcttgtatac ttttccaatc ttctaaacct ataatcacag cattattttc ggcattattg
     9061 ccactaatat aaattggttc gtgattatta ttaacatttt ttagtaattg ataaaaatct
     9121 tttctcgctt ctgtagggct agtgataatc atataaaccc tcctttgttt tctgttacgc
     9181 taattatagc gtacgcactt gagtacgtca atattgccaa cgagttcatc gtattcttaa
     9241 tacctatatg ctatcgtaca caagcttttg ttcttttctt ccaacatacc gtctataatg
     9301 ctcaaaaaga aatcagcagt ggaacacact acgttcccta ccgctttatc atttttcagg
     9361 cttaaatatt tttaaaattt tgtgaggaat ccgcttaaaa aactcatatc ttcaaaaaaa
     9421 atgacaaaat ttaaattttt gaataacatc attttttagt aaatgttata atttctttat
     9481 aatacaaata tcgaaagaag gcgactgact ttgaaaaaat tatgttcatt aattgtagta
     9541 gcattaattt gtatcattgc attatcagct tgtggtaaag aacaaaccaa aacatatgaa
     9601 ggtgatgtta gtggtaaaca tgtactaact tctatcacat ataaagatga taaggtttta
     9661 aaacagtcta caatcaacac aattaaatat gacgatctag gtatggataa agacgaagcc
     9721 aaaaagttat tcgccaaatc tgaaagtatt ttcaaagacc ttaaaggcgt aaaatacaaa
     9781 gtagactata aagataaaaa agcaattgaa cacttagaca tagattacac agaagttgac
     9841 atgaaaaaat taaataaacg tcttggtgtt tcaactaaag aaaataaaga tattagtttt
     9901 gaaaaacttg aaaagcaatt aaagcacaga ggtttaaaag aaaaagataa aatggacgac
     9961 aaatagttta taacataaaa atgccctcag ataagactaa ggatacaaac cttaattcat
    10021 attctgaggg ctttaatatt tgaaattctt gtgtgaccag catccactac taatataaaa
    10081 ttatttgcag taacactaaa atccgctgct ttcattttct cgaaatagat aaatcaacta
    10141 atcaatttca atttataatc atgtatcgtt tgtaactcac catcgacttt tcgatataca
    10201 atatgatcag cagtaatttc tgtaggactg gatacgccaa cagctgctgc aatattgaat
    10261 aagccttcat gcaaacttgt tacatagttt gtgacacgat attgcttttc tccaacaatc
    10321 aatgcttttt cttttttcgc atctgtcgtt gcaacaccta caggacatgt attcatatgg
    10381 cattgttgac tcataataca accgacacta atcatcatgc cacgtgcgat atttacaaaa
    10441 tctgcaccta aacctagtgc aatcgcaatt ttatctggtg tcactaactt accagatgcc
    10501 gccaatttca ctttatctcg aataccatat ttttctaaca tgccagacac aataggtaga
    10561 gctgtaaata gcggtaagcc aacaccatct tgtaattctt ggaatgttgc accagtacca
    10621 ccttcaccac catcaatcgt aataaagctt ggatacttat ctagttccac catcgtacgt
    10681 acaagtgttt caatttctga aactttgctt actacaattt tgaatcctac tggtttttga
    10741 cctaattgct gcaactgatc gacgaaacga atcaaatctt cagcattatg aataaattcg
    10801 taacggttag gtgaattgat tgttttataa ggttcaacat ttcggatttt agcaatttct
    10861 tcgtttacct tttcagcttc catatgacca ccacgagtct tagcaccttg tgccaacttc
    10921 agctcaaatg cgcgtacgtt agataactgt gcgacctctt taaataaacc ttcactaaaa
    10981 ttaccttctt tatcacgaac accaaataaa ccgggaccaa tttggaaaat gatatcccca
    11041 ttacctttta aatgatattc tgataagcca ccttcacctg tattcatcca agtgcccgct
    11101 ttagctagac ctttagataa agctgtaatg gcattttttc ctaaagcgcc ataactcata
    11161 ccagattgtc ctacgatacg ttttaaaata aatggatgtt ttaaatgttc acctaatttt
    11221 attgcatggt catcacttaa gtaatacgga tcaatctttg tcggtacacg atattcttca
    11281 cgactaaata aacgctcatt cgcgatttta taaatgaatg ttgataacaa tgttgtatta
    11341 tctactgaaa tctcattacg ttgcatcgga aacattgtgt tctgtatgta aaagccgtct
    11401 tgataatctt tagtagtacc gaagctggtc atacgagagt tatattttcc agccaaaacg
    11461 atatttttat aatcattacg tgaaaaaggt ttcccttcat tatccccaga aaataaatac
    11521 tgacgtaatt ccggtcccat tttttctgaa atatatctaa tacgtgctag taaaggataa
    11581 ttccttaata cactatgttg tgattgtctt ttatctttaa ttaaccaaat aagcccgata
    11641 acaataaccg taagcaggaa gcctacaacg ataatgttaa ctataaattg catgactgta
    11701 agaaacgtca ttacaatacc tcccccccaa aatttcaatt caatatttat gatacacctt
    11761 acaaaacaaa acacaatgga agcgcttcat tttataaaac aattttatga tatgtttttc
    11821 attttaaatt ttaatgtata aaacatacaa tacaaagtaa tatgtgctaa agtatctata
    11881 taatacaact atttaagagg tatactatgt caaatacaaa taaacattac atagaagaag
    11941 aatacgctac tgaacaatcg cgttttttca aacgtgatat tggatttatt ttcctttata
    12001 tatttttggt taacatcttg ccaatcatta tcgtcttttt aacttttggg ttagtagctg
    12061 tattcactca acaagcccca tggggtttct cttttcctat ttcaatgaac attagctatt
    12121 tactcgcagt tattatttca ctagctattt ttcgtcggat gcatgaagat gcatttgttc
    12181 cgatgatacg tacgcaaatc attgccagca ccaaatataa atggcatatt cttatatcat
    12241 ttacactaag tgtcgtactc tttttacttt taaattattt cgatattttc gcactaaatg
    12301 tagatgcctt tactgtcttt gacatttacc cgctcattag agattatgat tccatcagtt
    12361 taatagtaat gttgtggtta accattatat taaatacttt gatttgccaa cttattttcc
    12421 gtcatatttt aattcaagaa ttaagcagat taataccttt aaagattaca atagtattat
    12481 ccgttatcct tgaaacactg tactattatc catacattaa tacatggtgg gaattcattc
    12541 cagcattgat actagctagt agtgcgactt acttatattt aaagtcaaac cgtaatttta
    12601 tggtgagcta tttctatcaa ttagcagtta tactcgtttt gcatattttc atgtaaaatt
    12661 tttcagagta ttatccatta tccatacaca tcaaaaagca cacttaaaag tcagtatcac
    12721 aactcacttt taagcgtgct ttatttagat atactgtcgt tctaaaaacg agccatatag
    12781 agagcctgag acataaatca atgttcaatg ctctacaaag ttatattggc agtagttgac
    12841 tgaacgaaaa tgcgcttgta acaagctttt ttcaattcta gtcaaccttg ccggggtggg
    12901 acgacgaaat aaatttttcg aaaatatcat ttctgtccca ctcccatgaa tcgccatgct
    12961 caatatacct tttaaaattt aaatattcat taacttaata tgctttaatt cacttcatta
    13021 aagactactc gctggacgtg gtgttggctt tttcaagaaa ctcataatca ttattacaat
    13081 gactaacata ccacaaatta gatacatcca tttaaatcct actaaatcgg aaataggtcc
    13141 catcaatgcg ccacctaacg atatacctaa gtctgcacag gcaataaata aacctaacaa
    13201 catattacga cctacttttg gtaagacgaa gcttaagtat gatgttaatg ttgggtacac
    13261 cattgcttgc gtcattccta ttaatatcgc actaccatag aaaataattg cacctacttg
    13321 cggaccaaat gccactacaa atgacgcgat tactaataat gatagtacag ataccatata
    13381 tttaggatgc cacataccat ctgacggaat gtatttcctt aagtaaaatc ttgccgcaac
    13441 aactgcgatg gcctgtattg tcaaaaagat tcccgcattc gcgaatccta aactcactgt
    13501 gtataacggt acaaatgtac taactgcacc aaatacaatc gatgcaacaa tcatgataat
    13561 accactgttc aacaactctt tatttttgaa aaattgcgca aaaacagtta cagcgttaaa
    13621 cggcattttt tcaatcttat ctgacgtatc gggttcctgt tcagcaaagg tcacgcgata
    13681 gccaaagaat gttgttgtta atgcgataaa gataatgaca attgcaaata gtgaaatatt
    13741 atttgcattc caaataccta cggcaactaa tggtccaatt aagtttggaa tcgttgaaaa
    13801 tagcgagtac aatgatacac cttcagaacg atgttcctct ggtaatgcat caataatacc
    13861 taactgtaaa gacatagaaa agaatgccgt acacacacct tgcataacac gtgctacgaa
    13921 ataaccttct aatccagtaa aaccataaat aattaaagct atggcattga tgatcaaaat
    13981 aattcttaaa actttaatgg gaccgacacg agcaataatt tgtcctgccc atggtcgaaa
    14041 caccattgct gttaacatgt atgcccccat aacgataccg ataaccgtat tcgttgcgcc
    14101 taaatcatgc cctcgtaacg gtataaatac gtttaagatt gcattggcac taaagaacat
    14161 caatgttaat atatataatc tcaaaaaggg ccaagccatt gcacctttca ttatctcact
    14221 ccttagaatg atagttgttt ttctattaat tctcttgtat aagcattgtc acttttatgc
    14281 aatgcgcttg tcggaatttg ttcttctatt tttccgtttt taaaaataat taattgatca
    14341 cataaatacg tggcagcttg aatatcatgt gtgataaaaa tataactcaa ctgacgcgtt
    14401 tcacgtaaat gaatcaataa atctaatatt tgtgtttgaa ttgacatgtc gagtgaacta
    14461 atggcttcat caaacaaaat atatttaggg ttaatacata ttgcacgcgc aatcgcaaca
    14521 cgctgcgctt ctccacctga taacatatta ggatatttat ccatgtatgc cttagataga
    14581 ccgacttctt ccaacaatgt aattgcttgg acttccataa cttctttagg ttgtccatca
    14641 cattgacaca tcacttcaaa taagatttct ctaacagtct gaaatgggtg taatgatgac
    14701 gtataatctt gaaatacagc accaatttga tgacgtctga ctttcttctt atgcatcggt
    14761 agatcattta aggttacaca gcctttatcc ggtttctcaa tacctaatat catacgactc
    14821 aacgtcgatt taccgctacc actttctccg ataatcgcaa tcgtcgcacc gattggacac
    14881 tcaaatgaca cacctttcac gataggtgtt cgacgacgct taaaaacatg tgcgctttga
    14941 tatgattttt caacatctgt aactttaatc atgtacatca cccctcatca catgtttaaa
    15001 atgatcatta atcttcttct tcgttgataa taaatacttc gtataaacat gttctggatg
    15061 atgcaagact gattcacgtg taccatgctc tatcagttga ccatttttca tcacaacaac
    15121 acggtctgca atcttgttaa taaccgttaa atcatgtgaa atgaaaatca tcgcacagtc
    15181 aaagtgtttt ttaatatcta taaatgcttc cagtacatca tattgtgtaa ttgtatctaa
    15241 agccgttgtc ggctcatcag caatgattaa ctttggtttc aaagctaacg ctaaagcaat
    15301 catcaatcgc tgtaacattc ctcctgataa catgtaaggg tatgatttta atatacgttt
    15361 aggatctttc aaacttaaat aatccatata ttcaatcaat gtcttttcaa tttcttgtgt
    15421 agacattgac gtatgtactt tcatagtctc aaacatttgt ttaccgacag tagttgatgg
    15481 gtcaaaggca cgactacctt gttgcatgac catcgcaata tctttaccac ggtacttttt
    15541 ccgttgcgat tcagataatg acaacattga tgtaccatca aagataattt cacctgtcac
    15601 cccgagtcgt tcgggattca aaccaataat cgatttgcat gtaattgatt taccgctacc
    15661 actttctcca ataacgccta aagtttcacc cttagttaat gtaaaattca catcactcac
    15721 gagtggttga tctgtccagg tatctgtaat cgtcaaatgc ttaactgtta acaatgtcat
    15781 gattgcacca ctcctttttt cacagaacga agtttatctt tagaagagat gcggggatca
    15841 atagcaattt gtaaagcatc ggataagaag ttaaatgcca tcactataat cactatggca
    15901 atacctggcg caaacatcat ttcaggatgt gtaaacatca cttttctagc ttcgttaagc
    15961 atcatgcccc actctgcagt aggcgctttg acacctaatc ctaaaaatga aaagccagat
    16021 atttgcaaga tcattgaaca catcgaacta ctagagatga tagcaatatc tgctaatgtt
    16081 aacggcataa tatgtttgtg aataattttc atatcattca taccgattgt tttagcaaat
    16141 ctgacatggt cagaagcagt gtactgcata acacttgtac gtataacacg acagaaccat
    16201 gcccaacgcg tcaaaataaa tgccatgata atattttcgg cacccattcc aaacaatgca
    16261 attaatgcta acgttacaac ataacttggg aatgccaaca taacatcaca cgcacgcatg
    16321 attaaggcgt caacaaaccc ttggaaatat cctgataaga atcctaaaat agatccaata
    16381 agtacagaaa caaatagcgc aacaaagaca tataacaaac ttggtctaat cgcataaatt
    16441 aacctagtta aaatatctct acctaaatgg tcagtaccta gtagatgttg aaaactgatg
    16501 ccagcaaatt tgtttgctgt atcgatatgg ttaggatcat aaaatgtcac aagtggtgct
    16561 gctaatccta aaaagacata taatacaata atgcctaaag caattactgc acctttatct
    16621 tgtaataatc gttttaaaat tatcatcgtg cgccctccct taatcttgga tttaatagcg
    16681 cattaatgat atctgctaat gtattaaata caataaataa taccgctaca attaatacat
    16741 atgcttgaat gactggaaaa tcgtgttcaa gtattgcttt taaacttaat tgacctagtc
    16801 caggccatgc aaagatatac tcgataacaa ctagtccacc cattatcatt ggtatagaca
    16861 tacaaaagat tgataccgca acttgtatag cattacgcaa cacatgcaac attaatgtga
    16921 tagatttcac accgcttgct cttaaataaa gtacataatc ttcatttaat tgttccacca
    16981 tcgagcgtct aacatttcta aagtaaatac cagcataggc aatcgtaata acgatcactg
    17041 gcaatatgta actttctggg cctgttaatc cagaagtcgg caatatgttt aacttcactg
    17101 aaacgtaaat aataagtatt gaagctatcc aatatgatgg taatgcagtt agaaagaaag
    17161 ccactgaacg tatcgcacga tcagtgaact ttcctctttt taatgcacta actacaccta
    17221 aaataattga tgtaatcatc accataacac ttgaaattat tgttaatttc aatgtgttca
    17281 taaatgctgg gccaatgcgt tcagcaacag gatcccctgt aatgtaactt gtaccaaaat
    17341 taaattgcat cgcttcaagt aaccagtttt tatattgaat taataatgga tcattgaaac
    17401 cgtacttttc attcgtttct gcaatcaact ctggtgttac atttggcgtt ccttgtgcat
    17461 gtaaaattgt cacagctgga ttttcatttg taatatacgt caatagaaat gtcataaaac
    17521 ttactacaat cactaatgga aacatgagcg caatacgttt taagataaat ttgaacatct
    17581 aattgctcct ttatttatac tgcatttcat tgaatggtaa ttcatactgt gattgtgtga
    17641 atgatacttt ttctaaatct ttcggcgcaa caactgtcat actaccgtgt gaaataggga
    17701 taaagatacc ttcatcatca atttgtttca aaatgttttt ataagcgtct gaacgctctt
    17761 taccgttttg gattttaaat gcgtcatcaa tgctgttgta tattttatct ttgttctcaa
    17821 tgcctgatgt tgcactttca taaccatttt tcgctttaaa tgctgcaata gtactttgtg
    17881 gatcgtacaa taatccccaa gtttggttga acattaagtc ataatcacca gaagtacgac
    17941 gttcagcaat tttatctgat gtttcgccat tgatgtttaa cttaataccc attttcttaa
    18001 attctgcttg taagtattct gcttgttctt tttgacttga agaacctttg tcatagtaca
    18061 ttgccatttc aaggttttta ccatcttttt gacgaacatc actgtcttta cctttcttcc
    18121 aaccagcttc atctaataat gattctgctt ttttaaggtc atacttacgt gttggcatat
    18181 cgaaattaat gtctgttaca tttttcgcaa ataattgagt tgctggtttt tcttgaccat
    18241 ctaaaatttc tttggcaatt ttatctctgt ttaccatatg accaatcgct tgtctgactg
    18301 ttttgtcact gacagcgtta tcttttttac cagaattgac aactaacatt ttcgtattca
    18361 taggttgact acgcttaact tgatagtcac ctgtatcttt caattgtttt aaagagtctt
    18421 tgtctaagct atccgtacct ctatcatctg tgaaggcaaa gttcgtttca ccttttttca
    18481 ttgataggaa tgctgtttca ccagcaggca ttacttttgc ttgtactttg ttaagtttag
    18541 acttttcgcc ccagtattga tcatttttgt taaagtctgc agactcatct tttttgtgtt
    18601 cacctaattt aaatggacca gtaccatcga actttttaac gccatctttt gttgtaccgt
    18661 ttttaaagtc ttttggagac acaaatacat atggacgagg catcgctaat tcagccaatg
    18721 caggttgata tgcttctttc aaattcaatt caaccgtgta cttatcttta actttaacat
    18781 tgtcaattaa tgttgaaatc tttaaccaag aatgcaattt tttattttgt tgaaccgcat
    18841 caatattttt cttaactgcg tcagcatcaa atgttgttcc atcatggaat ttcacatcat
    18901 ctcttaaatg gaatgtataa gtcttcccat cttcagacac atcccatttt ttagctagta
    18961 aaggcttaat accatctttc gtgttacgta caagcggctc gtatatcata ctttcagcag
    19021 acattgatcc accgtaaaca tgcggattca tatcaccgat atctttaacc gtcgtatacg
    19081 ttaattgctt gttttctttt ttctcctcta aacctttatt accgccacaa ccagttaaaa
    19141 ttagccctga tgcaaataac attgcactca ttttagttag ttttctcatt tgcttttcct
    19201 ctttctaaat tgataagttg cattacttaa tcaaatcgta atgattattt ttctcaatta
    19261 tttgcttatt tttatgtaaa tgtcaaacat aattcaataa tttttttcta ttataaaact
    19321 tcaaaccctt attatgaaag cgttctattg atttccaaaa attttgtgac gagtgcctta
    19381 tctccttcaa atagatttgt attaaattga gaagatagtt gttgatcttg gtgcatatcc
    19441 ttgtacgcct ggcaacttgc ttcatagcga gttaggaact gatcaatcat tggcgttttg
    19501 atacctaaca ttttcccaat atgctgaatc atcgccgttc tgtaataatc ttcacttggc
    19561 attcttggaa tttgaacaac atcctgttca tttttataga cttgcttaaa tggtacagct
    19621 gaaaaatcaa agtaatgtcc gttttcgtct ggctgtgaaa atggatcaat gaggattgcg
    19681 gtgtatctta cataaagcag atattcttgt aagatatctg gcaagatttc gaaatgctca
    19741 atatcacctt catccaaagt ttcaggacgt actggataat tttccttcac cataaattga
    19801 agcaggttga ctgacggcac tctaaatgct tgtaaaatag ccatcatttc cttccacatt
    19861 aaacgcattt cacggattaa tgtcatcgtt atcggtcctt caggaaataa cttatacaca
    19921 taaaccggta catccgttcc ttcgaaaatg gctttcaatg aaaagtcatt cataaatagt
    19981 ggcgggtgca cataaagcga actgttacgt gtttcagcat gcagtggcga ttcaacgact
    20041 tctaattgaa tcttcaattg ctcagctaaa gcagagattc gttgacacat tgttgagttt
    20101 gaatgtgtcg atcccatgta caatttcttt tttacacctg ttgtcaacac atgattaggt
    20161 gcttctttat caacaatacg tgtatcgcca agataagttg aaaatgaaat cacttcgata
    20221 tcctgactga acttagacat aaattgttcc acaatcattt gcgatccaaa tgtcggtgaa
    20281 attaaaatga catgtttgac actttgcaaa gtttctaacg acaattgctg tagtgtgtca
    20341 taataagcat ctgctgtgca tgccatgaca accgtttcgt attcaccctt aacgttttta
    20401 acatctttat acaaacgatt aatttcaaac ttaccttcca gatgttgatg cgcctcgttt
    20461 tgtattttga cttcaaattg tttctctttt ttatacgctt gatataagcg ttttgatttt
    20521 tctgatgttg aggcacgtcc aaccatatca atctcataat ctgattttaa atagcaaata
    20581 ttcgctaatt ggattgcgac cggaccagtg cctatcatta ataatttaga catccgtaat
    20641 acctaccttt atagctgctt ttttataaag tgctatatca aaaatttgct gtggtctcat
    20701 atgtttattc acacattgcc acttatcttc cgctgtttct tgtgacggat aattaaatat
    20761 tgctttgatg ccatcaccaa agcgcattgc aactacgaca ttttcatttg ttaaatcata
    20821 taattcttct aaaatgctgt actttaaagg aattgtcgag ctgaatatga tatgcgtcac
    20881 atctttgata tctttaagtt cagatacctt ttgatccgta attgttatat cttcatttgg
    20941 tgctaagacg ttaacgattc tgcgccctag gtcaacggct tgtggatcaa tatcaatacc
    21001 gataactgaa gcacctgttt cttttgctac ttgaattaac gtcattggat atgcacctga
    21061 accaactaac aataatttgt cattgctagt gatactacat tgtccaaact cttcatcaat
    21121 acaatgttct atattgtcaa agtaacctgt ggtagacgcc tgtccgtcta atagacgtct
    21181 agctctaatg acttccactt gtttaacaca ctgcgctgta atatattgca gtgattttat
    21241 taattgtgct ttttcttcaa cgtcacgcca agcattaaat tgttgttcat aaataggatt
    21301 taaaataaat tcactatagt catccatcaa tgtttctaat gcttcgatat attgatcgtc
    21361 ttgtaataca cgctcgtaat gcgcttcaaa cttttccaaa tattgttgta atatcaattt
    21421 gatttcatta ttaaagttat tcattgtagg ctccttattc tatatatgct tttcctgtag
    21481 ctacagttgt aacctgtcct ttaattgaag tttgatatcc caattgatga catcgctttg
    21541 atgtcactaa aatactgccc cctggctgat gtactgtaaa atctttgcat gcgtcattac
    21601 gttgataatt attaaaaacc ccaattgatg ctgtaccaga accacagcta ttttcccaaa
    21661 ttaaactttg aatttctggt atatagatta atggctgtaa aaattgacgt tgttcatcaa
    21721 aaagcatcat acctactgtt ttatatttgt gactccattg ttgctcacgc acaaatgctt
    21781 caaccaaatg ttgaatttca gttgttactt gtttaactgg aatcacataa tgtacatatg
    21841 tttcataaat aatttctaat gctttccatg aatgattacc catattaatt gttgttggca
    21901 caacacgatg ggcttgtggc atttgaactt catagtattg gcaatcatga attgcgcatt
    21961 gcactaaatc cgaacagcca gataccttca ccttaaactg ttggtcttta agcaaatgac
    22021 tttcctgcaa atgatgtata tatgacatcg tcgcattacc gcaaaattca ttaccgctca
    22081 taactaagtg aaaatcattg ccatcatcat tttgtgttga ttctataaag cctacctgtt
    22141 cacaacatac atgtgttgcg gccatcaact gattggcgat agatgcatat tcactagcat
    22201 catgttttga atgaacaagt atcgtcatat tccccgaagg attatactta gaaaattcta
    22261 taacctgccg attcatacga cactccttta gatgtatttt tagagcctct tttaccataa
    22321 gtaattagag gctcttatgc agttggtgcg aagcaagcaa ctgtattcct ctaaaactgt
    22381 aatttttaga agatgaacct aatattttcc catctattag gtaagtcatg ctaacccgca
    22441 aaagcgaaaa ccatggctct tatgcagttg gtgcgaagca aacaactgta ttcctctaaa
    22501 ccttgtaatt tttataaaaa gaacctaata ttttcccatc tattaggtaa gtcatgctaa
    22561 tccgcatagt ggaaagcatg acttagtaat cggttgtttc atcaacatgc aaccgtaaac
    22621 cttatttaaa gttgcttctt gtggctctac aagtgaatgc agttgtccgt taacttcatt
    22681 cacttagatg cttttactgt tttcacctca actaaaactt caaaaaagtt gcagaaaaca
    22741 aatcgtaact attacgattt gattatatac tatattagtt gagaatcatt gtcaataaag
    22801 gttgtaaatg aatgcacatt tatattttga taatctttcc ataaacatcg tattctcagc
    22861 acattcaagt cttttgaaaa tttttatcaa acaaaaaaac cagcttcaac gtaaaatacg
    22921 ttaaaactag ctttaagcaa tacacttcat caaataaaca aacatttatt tttcaaaggt
    22981 taataattcc ccgtcatttg gtacaacaac tctattacct aagtcgttag aatttataaa
    23041 ttcattcagc tctttacgag ataaatgcca atgattgacc gcttccatat gcacaacaac
    23101 aatttgcgca agtggcaatg tattagcaac ttttaacaca tcatgttcat ccataactaa
    23161 cggcccacct tcaaagaatt gatttgcacc accattaaga acaacaacat ctggttgata
    23221 cgtttttaat gctttttcaa ccccttcaaa ccaaactgta tctgctgcta agtataatgt
    23281 cggctcttca gaatgtttta aaatcatgcc gtgaacatgt cctgtcatct tcaaaatttc
    23341 accatgacca tgttgagcat ctgttttaat caactcaatt tctccaatgt gtgtcacatc
    23401 attaaataca gaaacatttg taaacccata acgctctact tcactagcat cttcttcatt
    23461 ttgtgcgtaa attttaatat ctttcggcaa tacttcaatt gctttcggat caaaatgatc
    23521 aatatgcaaa tgcgttaaaa tcactaaatc gatgtcattt ataatgtctt caattgccat
    23581 gggtagttct acaagtggat ttttttgatc ttgtctcggt gaatttggaa aagggtcaaa
    23641 tgaaccttta tcacttaaca ttggatcaat caaaatgcgt ttacctccat actcaatcac
    23701 ggccgtggca tttcttatat gtctaatatt catgttaaat ccccctattt catatgtctg
    23761 tcattgcgac aatatgcata cattgccaat tcttttccac tggatatcga ttttaaataa
    23821 ttattccaat gtccgcttcc acgaatcatc acttaacatc tcgccaggcc atgtgtaagc
    23881 catcacacca ccatcaattc gaatcgtctc tccagttatg aatgaactgt cgtcagatgc
    23941 taagaagact actaatttag caacttcttc tggtttacct aaacgtccca gcggagtcat
    24001 ccatttttga ttttctctaa atgttttacc tgcatcatcc tcactcgtac ctgtcagttt
    24061 atctactaac ggggtttcaa ttgtacctgg tgcaattgca ttggatcgaa tgccatcacg
    24121 accatactca attgcgattg attttgtaaa attaatcact gcgcctttcg cagcattata
    24181 tcctgagcga tacaaatctt ctgcctgtcc tgaaaatgaa gacgtattaa caatagagcc
    24241 accttgattc atcattaaag gtaacatcat tttcgtcatt aaaattgtcc cacgcatatc
    24301 tacattcata atcttgtcat acacatctat tggatactca tgaattctac cagccgcatt
    24361 atccacaccg gcattattaa acaacacatc gattcttcca aactgttcct ttatgtcaga
    24421 cacaaagtct accacttgtt gttcatctga aatatccaca ttatacgcct tcgcattgtc
    24481 accgttactt ttaattttat cgacagtctc cgataccgct tcagctatgt ctaccgccaa
    24541 tacatacgca ccttcttgag ctaaagcgat tgcagaagct tgtccgatac ctgtacttgc
    24601 tcctgttacg actgcaactt tattttccaa acgtttcatt cagtcactcc tatacaacat
    24661 atcttaaact tacagtcctt attttccact gttcaatgct tcataaacct aatagataag
    24721 tctccaggca gtcttagcta ctctctgcta tacaatttct attgaataac tcaaaatatt
    24781 taacaatatt agtcttttca ttttctgaaa attgttactt ttgagagtat tttttgttac
    24841 actttaaata tttaacaaag gggggaatca ttgatgacat caaaacatca acaaaagggg
    24901 tctatcgtca atcgtttctt gaatagtgtt gaaaaaattg gaaataaatt gccagatcct
    24961 agcgtcttat tctttttaat gtgtgtgggc ttagccatta tgacgtgggt tatctcatta
    25021 tttaatgtat ctgttaagca tccaggtacg catcaaacca tttatattaa aaatataatt
    25081 agccatgatg gatttacgat gataatgaat gatacgatta aaaatttctc agagttccca
    25141 gcattaggct tagtactagc agtgatgatt ggtattggtg ttgcagagaa aacaggatac
    25201 ttcgataagt taatgatttc tgttgtgaat cgcgcaccac gatttttaat tttaccgact
    25261 attatattaa ttggtatttt aggtagtaca gccggcgatg ctgcgacaat tatcttgccg
    25321 ccgcttgcag caatgctttt tattaaaatt ggctatcacc ctattgctgg tttaacgatg
    25381 gcatatgctt ccgctgttgg aggatttgca gcaaatatag ttgttggtat gcaagatgct
    25441 ttggtctatt catttacaga accggcaaca cgtatcgttt cagattctat taaaacaaac
    25501 gttgctatga actggtactt tatcgcagcg agtgtcgttg tattacttcc tacgatattg
    25561 ctagttacaa ctaagctcat tattcctaga ttaggaaaat atgatgacag tttaatgcat
    25621 gatgaccatg aagaagcatc ttcacatatt actgacaaag aagcacatgc tttaaaatgg
    25681 gcaaatatca gtttcatagt cacaattatt ttattaatta ttacagctat tcctgaacat
    25741 agttttttaa gaaatgctaa aacaggcagc ttactagacg atgcgccatt aattaacggt
    25801 gtcggattaa ttattcttgt cgtattttta gtacctggat tagtttatgg gattttaagc
    25861 aaagaaatta aaaatacaaa agacttaggt aaaatgttcg gcgatgctgt aggatcaatg
    25921 ggaacattta tcgttattgt gttttttgca gcacagctac ttgcgtattt aaagtggagt
    25981 aatttaggaa ttatcgctgc tgttaaaggt gccaaattat tagaacatca aaacggtatt
    26041 gtattgatac taggtattat tgtactgagt gcaatggtca acatgttaat cggaagcgca
    26101 tcggctaaat ggggtatttt aggaccgata ttcgtaccaa tgttaatcct tatcggcttt
    26161 catcccgcat ttacgcaagt catttaccgt gtaggcgatt caattaccaa tccaattaca
    26221 ccgatgatgc cgtacttacc tttattatta acttatgcac aaaaatacga taaacgcatg
    26281 aaactcggag ccttactttc tagtttaatg ccgtattcaa tcgcgctaag cattgtatgg
    26341 acagtatttg tcatcatttg gttcttatta ggtatccctg ttggaccagg tggaccgata
    26401 ttcgttaaat aacagtattc aaagggataa attaaaaatg ccactataca agatttgacc
    26461 tgtatagtgg catgatttgt tatgatatag cgttcgagat gaaactctgc atttatatga
    26521 acaattatag tctatcacta ataatattta gtctgttcca accgttaatt tggtttacaa
    26581 caaagacaag atcaataatt tgttcttcat cataaaatga ttttagccgg tcaataattt
    26641 caaacttctt aaagtctttg attgaattta acatttctgc aaattcaagc gtcacttttt
    26701 cttgatcagt aaataaatct aaatgtctaa aactcaagac ttcatcaatt ttcatttgtg
    26761 ttacacccaa ttcctttaat tcttttttat ggatatcaac acaataatga caaccgttaa
    26821 tttttgaaat taataactta atcaatgcac taagttcatc attaaccggt gattgatgaa
    26881 taaacttttc accttggctc attacagaca ttaactctcc attttgtttc ttgtaattat
    26941 acggcatttg caatctctcc tttacattgt ttaataccaa tccagtgata ctacacttcg
    27001 aacaatattg gatagaattt aaaattctgt ataacatctt gtcaatctat gctttagtta
    27061 aaacatttag cgcttatatt taaaaaatat ataaaatatg aaaacagatt gaaaggatat
    27121 tataccttgc tctacccttt tttataaaaa atcacacaca tttgagaaaa tttgataatg
    27181 tcaataaatc acgtcatcgc cattgttatt cggtatataa tgtttttata atggctaaac
    27241 tattatttca tttacattaa tggggttcgc ttgtgttaat gtactgtaca aaactgggga
    27301 agtattggtg atgatgaagt gattgatatt aattgcgaaa caccttcgat agcaatgaca
    27361 tagattattg gaagattaaa tcaaaaataa agaagaccct agtggccttc ttttttgtct
    27421 aattcttctt tgatttcgtc aggtgatttt aattgatgcg ctggttttag taactcactt
    27481 aatctttcac tttctatcat agcaccacca aactgataat tatgttctgg tgtagcataa
    27541 gcagtaaaat tatctttttt gttttcattg atgtagcctt caattacggc atcgcccatg
    27601 ggtcctcttt ttaaacttgt gaaatgcaca gatttgatgg tattgggttc tttggtatta
    27661 tgctggagat agagtgtaat acgctcctgt tgttctttat agtatattgc tttttgtttt
    27721 tctttttcgt catatttcac ttttaaataa atgactgatg caactataca tatacataaa
    27781 atgacaccaa taattacaaa aacatgtttt ttgttcatta aagtaactcc taactttagt
    27841 gactctactt tttatttagt tcttttttta tatcatctgg tgattttaat tgatgcgctg
    27901 gttttagtaa ctcacttaat ctttcacttt taattaaatc acctacaaat tgaaagttat
    27961 tttcaggtga tgcataggca acaaaatcat cttctttatt ttcatttatg taaccttcaa
    28021 tcacagcact tcccatagga cttgtttcca attttgtgaa atgtacagat ttgattgtgt
    28081 tcggttctat agtattatgc ttaagataaa gtgtaatgcg cgcttgttgt tctttataat
    28141 aaattgattt ttgtttttct ttttcgtcat atttcatttt aaaatagata cttgcaacac
    28201 taattaatat gattaacata atactagtta atattaaaat tttctttttc gacatctatc
    28261 accagctcct aaaatgtggt ggaattttat acagtttaca tatttatgat actacaaaac
    28321 acactcttac aaagaaaatc tataatttta atctaggtca aggaaaagca gccaaaagtg
    28381 tttatataag atcaacgaaa tattgcgggt ataaagtggt taacagataa atacagtgga
    28441 aattgtacta aaaattcaac ttttcatttt tatatgtaag tatgattaac ttgaaaacaa
    28501 aattaaaacg gccgcatagt tttagcggtc gttcttttta gactctaatt ccttttttat
    28561 ctcatcaggt gatttggttt gatgtactgg ttttaataac gtgcttaaat ttttactttt
    28621 gattaaactt ccaccaaatt gataattatg ttctggagac ccatatgcaa caaaatcatc
    28681 ttctttattt tcatttatgt aaccttcaat tactgcatcg cccataggtc ctctttttaa
    28741 acttgtgaaa tgtacagttt tgatggtatt gggttcttta gtattatgat t
//
LOCUS       DAPDIM010000036        27377 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000036 DAPDIM010000000
VERSION     DAPDIM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 27377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27377
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.036"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            9..545
                     /locus_tag="RFE25_001605"
     CDS             9..545
                     /locus_tag="RFE25_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTPase"
                     /protein_id="HDU2816664.1"
                     /translation="MTNTLTIDQLQELLQIQKEFDDRIPTRNLNDTVASMIIEFVEWI
                     NTLEFFKNWKKQPGKPLDTQLDEIADYLAFSLQLTLTIVDEEDLEETTEVMVDLIENE
                     VTLPKLHSVYFVHVMHTLTEQFVKGIDNSIVQVLIMPFLYANTYYSIDQLIDAYKKKM
                     KRNHERQDGTADAGKGYV"
     gene            582..788
                     /locus_tag="RFE25_001606"
     CDS             582..788
                     /locus_tag="RFE25_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1381 domain-containing protein"
                     /protein_id="HDU2816665.1"
                     /translation="MTQYLVTTFKDSTGRKHTHITRAKSNQRFIVVEAESKEEAKEKY
                     EAQVKRDAVIKLGQLFENIRECGK"
     gene            785..934
                     /locus_tag="RFE25_001607"
                     /pseudo
     CDS             785..934
                     /locus_tag="RFE25_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500687.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            934..1134
                     /locus_tag="RFE25_001608"
     CDS             934..1134
                     /locus_tag="RFE25_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1514 family protein"
                     /protein_id="HDU2816666.1"
                     /translation="MWITMTIVFAILLLVCISINSDRAREIQALRYMNDYLLDEVVKT
                     KGYNGLEEYRIELKRMNNDIKK"
     gene            1162..1578
                     /locus_tag="RFE25_001609"
     CDS             1162..1578
                     /locus_tag="RFE25_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDU2816667.1"
                     /translation="MIKIEKHDIKKLEEYIQHIDNYRRELKMREYELLESHEPDNAGA
                     SKSNLPGNPIERCAIKKFSDNRYNTLRNIVNGVDRLIDESDEDTLELLRFRYWDCPIG
                     CYEWEDIAHYFGTSKTSILRRRNALIDKLAKYIGYV"
     gene            1810..2109
                     /locus_tag="RFE25_001610"
     CDS             1810..2109
                     /locus_tag="RFE25_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000988331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDU2816668.1"
                     /translation="MMTKDERIRFYKSKEWQTTRKRVLERDNYECQQCKRDGKLTTYD
                     KSKRKSLDVDHILSLEHHPEFAHDLNNLETLCIKCHNKKEKRFIKKENKWKDEKW"
     gene            2239..2583
                     /locus_tag="RFE25_001611"
     CDS             2239..2583
                     /locus_tag="RFE25_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816669.1"
                     /translation="MEIIVDENLVLKEKERLQVLYKDIPSNKLKVVDGLIIQAARLRV
                     MLDYMWEDIKEKGDYDLFTQSEKAPPYERERPVAKLFNARDAAYQKIIKQLSDLLPEE
                     KEDTETPSDDYL"
     gene            2580..4241
                     /locus_tag="RFE25_001612"
     CDS             2580..4241
                     /locus_tag="RFE25_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016187779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDU2816670.1"
                     /translation="MISNKYVDEYINLWKQGKIILNKERIDLFNYLQKHIYSRDDVYF
                     DEQKIEDCIKFIEKWYFPTLPFQRFIIANIFLIDKNTDEAFFTEFAIFMGRGGGKNGL
                     ISAISDFLSTPLHGVKEYHISIVANSEDQAKTSFDEIRTVLMDNKRNKTGKTPKAPYE
                     VSKAKIINRATKSVIRYNTSNTKTKDGGREGCVIFDEIHYFFGPEMVNVKRGGLGKKK
                     NRRTFYISTDGFVREGYIDAMKHKITSVLSGKVKNSRLFAFYCKLDDPKEVDDRQTWE
                     KANPMLHKPLSEYAKTLLSTIEEEYNDLPFNRSNKPEFMTKRMNLPEVDLEKVIAPWK
                     EILATNREIPNLDNQMCIGGLDFANIRDFASVGLLFRKNDDYIWLGHSFVRQGFLDDV
                     KLEPPIKEWEKMGLLTIVDDDVIEIEYIVDWFLKAREKYGLEKVIADNYRADIVRRAF
                     EDAGIKLEVLRNPKAIHGLLAPRIDTMFAKHNVIYGDNPLMRWFTNNVAVKVKPDGNK
                     EYIKKDENRRKTDGFMAFVHALYRADDIVDKDMSKALDALMSIDF"
     gene            4257..5444
                     /locus_tag="RFE25_001613"
     CDS             4257..5444
                     /locus_tag="RFE25_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDU2816671.1"
                     /translation="MSILEKIFKTRKDITYMLDLDMIEDLSQQAYVKRLAIDSCIEFV
                     ARAVAQSHFKVLEGNRIQKNDVYYKLNIKPNTDLSSDSFWQQVIYKLIYDNEVLIVVS
                     DSKELLIADSFYREEYALYDDIFKDVTVKDYTYQRTFTMQEVIYLKYNNNKVTHFVES
                     LFEDYGKIFGRMIGAQLKNYQIRGILKSASSAYDEKNIEKLQAFTNKLFNTFNKNQLA
                     IAPLIEGFDYEELSNGGKNSNMPFSELSELMRDAIKNVALMIGIPPGLIYGETADLEK
                     NTLVFEKFCLTPLLKKIQNELNAKLITQSMYLKDTRIEIVGVNKKDPLQYAEAIDKLV
                     SSGSFTRNEVRIMLGEEPSDNPELDEYLITKNYEKANSGENDEKEKDENTLKGGDEDE
                     SGD"
     gene            5428..6165
                     /locus_tag="RFE25_001614"
     CDS             5428..6165
                     /locus_tag="RFE25_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDU2816672.1"
                     /translation="MKVEIKGVIVSNEDKWVYEMLGMDSTCPKDVLTQLEFSDEDVDI
                     IINSNGGNLVAGSEIYTHLRAHKGKVNVRITAIAASAASLIAMAGDHIEMSPVARMMI
                     HNPSSIAQGEAKDLNHAAETLEHVGQIMAEAYAVRAGKNKQELVEMMARETWLNADEA
                     IEQGFADSKMFENDNMQIVASNTQVLSKDVLNRVTALVSKTPEVNIDIDAIANKVIEK
                     INMKEKESEIDVADSKVSANGFSRFLF"
     gene            6189..7334
                     /locus_tag="RFE25_001615"
     CDS             6189..7334
                     /locus_tag="RFE25_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001573791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDU2816673.1"
                     /translation="MTINLSETFANAKNEFINAVNNGEPQERQNELYGDMINQLFEET
                     KLQAKAEAERVSSLPKSAQSLSANQRSFFMDINKNVNYKEEKLLPEETIDRIFEDLTT
                     NHPLLADLGIKNAGLRLKFLKSETSGVAVWGKIYGEIKGQLDAAFSEETAIQNKLTAF
                     VVLPKDLNDFGPAWIERFVRVQIEEAFAVALETAFLKGTGKDQPIGLNRQVQKGVSVT
                     EGAYPEKEEQGTLTFANPRATVNELMQVFKYHSTNEKGKSVAVKGNVTMVVNPSDAFE
                     VQAQYTHLNANGVYVTALPFNLNVIESTVQEAGKVLTYVKGLYDGYLAGGINVQKFKE
                     TLALDDMDLYTAKQFAYGKAKDNKVAAVWKLDLKGHKPALEGTEETL"
     gene            7354..7638
                     /locus_tag="RFE25_001616"
     CDS             7354..7638
                     /locus_tag="RFE25_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016170801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816674.1"
                     /translation="MVKFKVVRAFKDIEHNQHKYKVGELYPAEGYNNPRVELLTNQIK
                     NKYDKVYIVPLDKLTKQELLELCESLQKKASSSMVKSEIVDLLNGEDNDD"
     gene            7628..7912
                     /locus_tag="RFE25_001617"
     CDS             7628..7912
                     /locus_tag="RFE25_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009560502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HDU2816675.1"
                     /translation="MTIDDLLVKFKSLEKIDHNSEDEYLKQLLKMSYERIKNQCGVFE
                     LENLIGQELILIRARYAYQDLLEHFNDNYRPEIIDFSLSLMEVSEDEESV"
     gene            7896..8258
                     /locus_tag="RFE25_001618"
     CDS             7896..8258
                     /locus_tag="RFE25_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HDU2816676.1"
                     /translation="MKKVFKKPRITTKRLNTRVHFYKYTENNGPEAGEKEEKLLYSCW
                     ASIDGVWLRELEQAISNGTQNDIKLYIRDPQGDYLPSEEHYLEIESRYFKNRLNIKQV
                     SPDLDNKDFIMIRGGYSS"
     gene            8255..8659
                     /locus_tag="RFE25_001619"
     CDS             8255..8659
                     /locus_tag="RFE25_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDU2816677.1"
                     /translation="MSVKVIGDKALERELEKRFGIKEMVKVQDKALIAGAKVIVEEVK
                     KQLKPSKDTGALINEVSFSKPEWINGKRTITVHWRGSKDRYKIVHLIEYGHVQKETGK
                     FIKPKAMGGVNRAIRQGQNKYFETLKRELKKL"
     gene            8656..9063
                     /locus_tag="RFE25_001620"
     CDS             8656..9063
                     /locus_tag="RFE25_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816678.1"
                     /translation="MIDILYKVHEVISQDRIIREHVNINNIKFNKYPNVKDTDVPFIV
                     IDDIDDPIPTTYTDGDECAYSYIVQIDVFVKYNDEYNARIIRNKISNRIQKLLWSELK
                     MGNVSNGKPEYIEEFKTYRSSRVYEGIFYKEEN"
     gene            9064..9708
                     /locus_tag="RFE25_001621"
     CDS             9064..9708
                     /locus_tag="RFE25_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDU2816679.1"
                     /translation="MAVKHASAPKAYINITGLGFAKLTKEGAELKYSDITKTRGLQKI
                     GVETGGELKTAYADGGPIESGNTDGEGKISLQMHAFPKEIRKIVFNEDYDEDGVYEEK
                     QGKQNNYVAVWFRQERRDGTFRTVLLPKVMFTNPKIDGETAEKDWDFSSEEVEGEALF
                     PLVDNKKSVRKYIFDSANMTNHGGDGEKGEEAFLKKILGEEYTGNVTEDNEETL"
     gene            9750..9974
                     /locus_tag="RFE25_001622"
     CDS             9750..9974
                     /locus_tag="RFE25_001622"
                     /inference="COORDINATES: protein motif:HMM:NF014427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HDU2816680.1"
                     /translation="MPDSIKTLKVGDTYDLNVVVEPSNQSKLLKYTTDQTNIVSINRD
                     GQVTAEAQGIATVKATVGNMSDTITINVEA"
     gene            10024..10374
                     /locus_tag="RFE25_001623"
     CDS             10024..10374
                     /locus_tag="RFE25_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816681.1"
                     /translation="MAKLKRNIIQLVEDPKANEIKLQTYLTPHFISFEIVYEAMDLID
                     DIEDENSTMKPREIADRLMDMVVKIYDNQFTVKDLKERMHAPDGMNALREQVIFITQG
                     QQTEETRNFIQNMK"
     gene            10401..10562
                     /locus_tag="RFE25_001624"
     CDS             10401..10562
                     /locus_tag="RFE25_001624"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816682.1"
                     /translation="MLKNMDTLMMDLIENGKDANEVLKMPFHYVLSIYQNKNNDISEE
                     KAEALIDAF"
     gene            10619..15148
                     /locus_tag="RFE25_001625"
     CDS             10619..15148
                     /locus_tag="RFE25_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001799555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDU2816683.1"
                     /translation="MGERIKGLSIGLDLDSANLNRSLTEIKRNFRTLNSDLKLTGNNF
                     KYTEKSTDSYKQRIKELDGTIAGYKKNIDDLAKQYDKVSQEQGENSTKAQNLRQEYNK
                     QANELNFLEKELEKTTAEFEEFKKAQVEAQRMAESGWGKTSKIFESMGPKLTKMGDGL
                     KSIGKGMMIGVTAPVLGIAAASGKAFAEVDKGLDTVTQATGATGGELKKLQNSFKDVY
                     GNFPADAETVGGVLGEVNTRLGFTGKELENATESFLKFSHITGSDGVQAVQLITRAMG
                     DAGIEASEYQSVLDMVAKAAQASGISVDTLADSITKYGAPMRAMGFEMKESIALFSQW
                     EKSGVNTEIAFSGLKKAISNWGKAGKNPREEFKKTLAEIERTPDIASATSLAIEAFGA
                     KAGPDLADAIKGGRFSYQEFLKTIEDSQGTVNQTFKDSESGSERFKVAMNKLKLVGAD
                     VWASIESAFAPVMEELIKKLSIAVDWFSSLSDGSKRSIVIFGGIAAAIGPVVFGLGVF
                     ISTVGNAVTVLAPLLASIAKADGLISFLSTKVPILGTVFTALTGPIGIVLGVLAGLAV
                     AFTIAYKKSETFRNFVNGAINSVKQTFSNFIQFIQPFIDSVKNIFKQAVSAIVDFAKD
                     IWSQINGFFNENGISIVQALQNICNFIKAIFEFILNFVIKPIMFAIWQVMQFIWPAVK
                     ALIVSTWENIKGVIQGALNIILGFIKFFSSLFTGNWRGVWDGIVMILKGTVQLIWNLI
                     QLWFVGKILGVVRYFGGLLKGLITIIWVAIIGVFKKSLSAIWNATKSIFGFLFNSVKS
                     IFTNMKNWLSNTWSSIRTNTIGKAQSLFSGVKSKFTNLWNATKEIFSNLRNWMSNIWN
                     SIKDNTVGIASRLWSKVRGIFTNMRDGLQSIISKIKSHIGGMVDAIKKGLNKLIDGLN
                     WVGGKLGMDKIPKLHTGTEHTHTTTRLVKNGKIARDTFATVGDKGHGNGPNGFRNEMI
                     EFPNGKRVITPNTDTTAYLPKGSKVYNGAQTYSMLNGTLPRFSLGTMWKDIKSGASSA
                     FNWTKDQIGKGTKWLGDKVGDVLDFIENPGKLLNYILEAFGIDFNSLTKGMGIAGDIT
                     KAAWSKIKKSATDWIKENLEAMGGGDLVGGILDPDKINYHYGRTAAYTAATGRPFHEG
                     VDFPFVYQEVRTPMGGRLTRMPFMSGGYGNYVKITSGVIDMLFAHLKNFSKSPPSGTM
                     VKPGDVVGLTGNTGFSTGPHLHFEMRRNGRHFDPEPYLRNAKKKGRLSIGGGDATSGS
                     GATYASRVIRQAQSILGGRYKGKWIHDQMMRVAKRESNYQSNAVNNWDINAQRGDPSR
                     GLFQIIGSTFRANAKRGYTNYNNPVHQGISAMQYIVRRYGWGGFKRAGDYAYATGGKV
                     FDGWYNLGEDGHPEWIIPTDPARRNDAMKILHYAAAEVRGKKASKNKRPSQLSSVNGF
                     DDPSLLLKMIEQQQQQIALLLKIAQSNDVIADKDYQPIIDEYAFDKKVNASIEKRERQ
                     ESTKVKFRKGGIAIQ"
     gene            15145..16629
                     /locus_tag="RFE25_001626"
     CDS             15145..16629
                     /locus_tag="RFE25_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HDU2816684.1"
                     /translation="MIDTIKVNNKTIPWLYVERGFEIPSFNYVLKTENVDGRSGAIYK
                     GRRLESYSFDIPLVVRNDYLSHNGIKTYDDVLNELVKFFNYEEQVKLQFKSKDWYWNA
                     YFEGPIKLHKEFTIPVKFTIKVVLTDPYKYSVTGNKNTAISDQVSVVNSGTADTPLIV
                     EARAIKPSSYFMITKNDEDYFMVGDDEVTKEVKDYMPPVYHSEFRDFKGWTKMITEDI
                     PSNDLGGKVGGDFVISNLGEGYKATNFPDAKGWVGAGTKRGLPKAMTDFQITYKCIVE
                     QKGKGAGRTAQHIYDSDGKLLASIGYENKYHDRKIGHIVVTLYNQKGDPKKIYDYQNK
                     PIMYNLDRIVVYMRLRRVGNKFSIKTWKFDHIKDPDRRKPIDMDEKEWIDGGKFYQRP
                     ASIIAIYSAKYNGYKWMEMNGLGSFNTEILPKPKGARDVIIQKGDLVKIDMQAKSVVI
                     NEEPMLSEKSFGSNYFNVDSGYSELIIQPENVFDTTVKWQDRYL"
     gene            16645..20427
                     /locus_tag="RFE25_001627"
     CDS             16645..20427
                     /locus_tag="RFE25_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816685.1"
                     /translation="MIHVLDFNDKIIDFLSTDDPSLVRAIHKRNVNDNSEMLELLISS
                     ERAEKFRERHRVIIRDSNKQWREFIINWVQDTMDGYTEIECIASYLADITTAKPYAPG
                     KFEKKTTSEALKDVLSDTGWEVSEQTEYDGLRTTSWTSYQTRYEVLKQLCTTYKMVLD
                     FYIELSSNTVKGRYVVLKKKNSLFKGKEIEYGKDLVGLTRKIDMSEIKTALIAVGPEN
                     DKGKRLELVVTDDEAQSQFNLPMRYIWGIYEPQSDDQNMNETRLSSLAKTELNKRKSA
                     VMSYEITSTDLEVTYPHEIISIGDTVRVKHRDFNPPLYVEAEVIAEEYNIISENSTYT
                     FGQPKEFKESELREEFNKRLNLIHQKLNDNISNINTIVKDVVDGELEYFERKIHKSDT
                     PPENPVNDMLWYDTSNPDVAVLRRYWNGRWIEETPNDVEKLGGITREKALFSELNNIF
                     INLSIQHASLLSEATELLNSEYLVDNDLKADLQASLDAVIDVYNQIKNNLESMTPETA
                     TIGRLVDTKTLFLEYRKKLQDVYTDVEDVKIAISDRFKLLQSQYTDEKYKEALEIIAT
                     KFGLTVNEDLQLVGEPNVVKSAIEAARESTKEQLRDYVKTSDYKTDKDGIVERLDTAE
                     AERTTLKGEIKDKVTLNEYRNGLEEQKQYTDDQLSDLSNNPEIKASIEQANQEAQEAL
                     KSYIDAQDDLKEKESQAYADGKISEEEQRAIQDAQAKLEEAKQNAELKARNAEKKANA
                     YTDNKVKESTDAQRKTLTRYGSQIIQNGKEIKLRTTKEEFNASKRTLSRVLADITVNA
                     MKGIYLRYDENGAITSHTIDKDGVKISGDKVDITANREFNVVANNINNKVGKNDIVNS
                     LNLSNEGLDINVNRIGIKGGNANRYVQVQNDFIELGGIVQRTWKGKRSTDDIFTRLKD
                     GHLRFRNNTAGGSLYMSHFGISTYIDGEGEDGGSSGTIQWWDKTYSDSGMNGITINSY
                     GGVVALTSDYNRIIIDSYASANIESREAPIYLSPNTKNKPGLNRFAFTLSNADSAYET
                     DGYIMFGSDENYKYGAGLRFSKRSNKGLVQVVNGDYATGGDTTIESGMGKFNIVKRRD
                     GNSYVSIQSYDLLAVGSDNAGDRVASNSIYKRTYSAPANLHITSAGTIGRATSAKKYK
                     ISIENQYINEDDQFSHSKEILKLPIRTWFDKYESEIMAKELESGKKLSDDTFKLSRHT
                     GLIAEEVEELGFNEFVIYDDNGEIEGIAYDRLWVHLIPIIKNQQSKIEKLEELINE"
     gene            20420..20572
                     /locus_tag="RFE25_001628"
     CDS             20420..20572
                     /locus_tag="RFE25_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816686.1"
                     /translation="MNDSNQGLQANPQYTIHYLSQEITRLTQENAMLKAYIQEQNEKS
                     KSAEEE"
     gene            20618..20905
                     /locus_tag="RFE25_001629"
     CDS             20618..20905
                     /locus_tag="RFE25_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816687.1"
                     /translation="MANEIIKKTERFILVQIDKEGTERVLYQDFVGSFTTSDSASYAQ
                     DFKSEENAKKIAETLNLLYQLTGNQNGVKVVKEVVDRTDLSSDKSVDSETM"
     gene            20961..21335
                     /locus_tag="RFE25_001630"
     CDS             20961..21335
                     /locus_tag="RFE25_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816688.1"
                     /translation="MDDIQKIKKELSELVERVDDVEILANETADHVLELREEHKQHHN
                     ELRESHKELKDKQDKVVDENLEQTKILNRIEERYQTQVDVAQKNEEKTLAQNKWLVGA
                     IWALVTIVMIAVITASITALLP"
     gene            21708..22481
                     /gene="sea"
                     /locus_tag="RFE25_001631"
     CDS             21708..22481
                     /gene="sea"
                     /locus_tag="RFE25_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type A"
                     /protein_id="HDU2816689.1"
                     /translation="MKKTAFTLLLFIALTLTTSPLVNGSEKSEEINEKDLRKKSELQG
                     TALGNLKQIYYYNEKAKTENKESHDQFLQHTILFKGFFTDHSWYNDLLVDFDSKDIVD
                     KYKGKKVDLYGAYYGYQCAGGTPNKTACMYGGVTLHDNNRLTEEKKVPINLWLDGKQN
                     TVPLETVKTNKKNVTVQELDLQARRYLQEKYNLYNSDVFDGKVQRGLIVFHTSTEPSV
                     NYDLFGAQGQYSNTLLRIYRDNKTINSENMHIDIYLYTS"
     gene            22590..22766
                     /locus_tag="RFE25_001632"
     CDS             22590..22766
                     /locus_tag="RFE25_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HDU2816690.1"
                     /translation="MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIAL
                     IGLVIKLIELSNKK"
     gene            complement(22819..22926)
                     /locus_tag="RFE25_001633"
     CDS             complement(22819..22926)
                     /locus_tag="RFE25_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816691.1"
                     /translation="MIFILWCVNLYIEKGQHAQTCYPSEPVKKTVAILD"
     gene            22978..23232
                     /locus_tag="RFE25_001634"
     CDS             22978..23232
                     /locus_tag="RFE25_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDU2816692.1"
                     /translation="MINWKIRMKQKSFWVAILSAIFLFAQNIAKAIGYDIQVYTEQLT
                     DGLNAILGFLVLTGVIQDPTTKGIGDSHQALEYEEPRRKY"
     gene            23244..23999
                     /locus_tag="RFE25_001635"
     CDS             23244..23999
                     /locus_tag="RFE25_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2816693.1"
                     /translation="MKTYSEARARLRWYQGRYIDFDGWYGYQCADLAVDYIYWLLEIR
                     MWGNAKDAINNDFKNMATVYENTPSFVPQIGDVAVFTKGIYKQYGHIGLVFNGGNTNQ
                     FLILEQNYDGNANTPAKLRWDNYYGCTHFIRPKYKSEGLMNKITNKVKPPAQKAVGKS
                     ASKITVGSKAPYNLKWSKGAYFNAKIDGLGATSATRYGDNRTNYRFDVGQAVYAPGTL
                     IYVFEIIDGWCRIYWNNHNEWIWHERLIVKEVF"
     gene            24190..24681
                     /gene="sak"
                     /locus_tag="RFE25_001636"
     CDS             24190..24681
                     /gene="sak"
                     /locus_tag="RFE25_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylokinase"
                     /protein_id="HDU2816694.1"
                     /translation="MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASY
                     FEPTGPYLMVNVTGVDGKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKE
                     FRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVI
                     EKK"
     gene            25332..25667
                     /locus_tag="RFE25_001637"
                     /pseudo
     CDS             25332..25667
                     /locus_tag="RFE25_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500032.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
     gene            26178..26528
                     /gene="scn"
                     /locus_tag="RFE25_001638"
     CDS             26178..26528
                     /gene="scn"
                     /locus_tag="RFE25_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement inhibitor SCIN-A"
                     /protein_id="HDU2816695.1"
                     /translation="MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNE
                     KLANELKSLLDELNVNELATGSLNTYYKRTIKISGQKAMYALKSKDFKKMSEAKYQLQ
                     KIYNEIDEALKSKY"
     gene            complement(26581..26841)
                     /locus_tag="RFE25_001639"
     CDS             complement(26581..26841)
                     /locus_tag="RFE25_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816696.1"
                     /translation="MCIVIYLIYSLIVYFICIINFFIMAAPFLMTNADYVWTPMTTVT
                     LFILSLIIFLIFIKTKDVVHLTIFILNLLFSILYCLPILFYL"
     gene            complement(27152..27331)
                     /locus_tag="RFE25_001640"
     CDS             complement(27152..27331)
                     /locus_tag="RFE25_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816697.1"
                     /translation="MKFKTTKECKSNNIFKRSQEINNSESEKGCLWGISMLILLFLLI
                     LFGITACSSSIHFIN"
BASE COUNT        10222 a         3687 c         5461 g         8007 t
ORIGIN      
        1 acaggaaaat gactaacaca ttaacaattg atcagttaca agagttatta caaatacaaa
       61 aggagttcga cgatagaata ccaactagaa atttaaatga cacagtagct agtatgatta
      121 ttgaatttgt agagtggatt aacacacttg agttttttaa aaattggaag aaacaaccag
      181 gtaagccact agatacacaa ttagatgaga ttgctgatta cttagctttc agtttgcaat
      241 taactctgac tattgttgat gaagaagatt tggaagaaac tactgaggtt atggttgatt
      301 tgattgaaaa tgaagttact ttacctaaac tacattcagt ttattttgtt catgtaatgc
      361 atacgctaac agaacaattt gtaaaaggta ttgataatag cattgtacaa gttttaataa
      421 tgccgttttt gtacgccaat acttactatt caattgatca actcattgac gcatacaaaa
      481 agaaaatgaa aaggaaccac gaaagacaag atggaacagc agacgcagga aaaggatacg
      541 tgtaaagaca tcttatatcg agtcaaggag gttttgggga agtgacacaa tacttagtca
      601 cgacattcaa agattcaaca ggacgcaagc atacacacat aactcgagct aagagcaatc
      661 aaaggtttat agttgttgag gcagagagta aagaagaagc gaaagagaag tacgaggcgc
      721 aagttaaaag agatgcagtt attaaattag gtcagttgtt tgaaaatata agggagtgtg
      781 ggaaatgatt aaacaaatac taagactatt attcttacta gcgatgtatg agctaggtaa
      841 gtatgtaact gagtaagtat atattatgat gacggctaat gatgatgtag aggcgccgag
      901 tgattacgtc tttcgagcgg aggtaagtga gtgatgtgga ttactatgac tattgtattt
      961 gctatattgc tattagtttg tatcagtatt aatagtgatc gtgcaagaga gatacaagca
     1021 ctcagatata tgaatgatta tctacttgat gaagtagtta aaactaaagg atacaacggg
     1081 ttagaagaat acaggattga attgaagcga atgaataacg atattaaaaa gtaatttata
     1141 ttatcggagg tattgcattg aatgataaag attgagaaac atgatatcaa aaagcttgaa
     1201 gaatacattc agcacatcga taactatcga agagagttga agatgcgaga atatgaatta
     1261 cttgaaagtc atgaaccaga taatgcagga gctagcaaaa gtaatttgcc aggtaatccg
     1321 attgaacgat gtgcaataaa gaagtttagt gataacagat acaatacatt aagaaatata
     1381 gttaatggtg tagatagact gatagatgag agcgatgagg atacgcttga gttattaagg
     1441 tttagatatt gggattgtcc tattggttgt tatgagtggg aagatatcgc gcattacttt
     1501 ggtacaagta agacaagtat attgcgtaga agaaatgcac tgatcgataa gttagcgaag
     1561 tatattggtt atgtgtagcg gactttcacc ctatgtaagt ccgcattaaa acagtttatt
     1621 atgttagtat cagattaata tttaaagtta ttaaatgcta atacaacgca tgaacaagag
     1681 gcgcatcact atgtgatgtg tctttttatt tatgaggtat gaacatgttc aaactaattg
     1741 taaatacatt actacacatc aagtatagat gcgtcttgat actacttaag ttatataagg
     1801 tgaaacatta tgatgactaa agacgaacgt atacgattct ataagtctaa agaatggcaa
     1861 acaacaagaa aaagagtgct agaaagagat aattatgaat gtcaacaatg taagcgagac
     1921 ggcaagttaa cgacatatga caaaagcaag cgtaagtcgt tggatgtaga tcatatatta
     1981 tcgctagaac atcatccgga gtttgctcat gacttaaaca atttagaaac actgtgtatt
     2041 aaatgtcaca acaaaaaaga aaagagattt ataaaaaaag aaaataaatg gaaagatgaa
     2101 aaatggtaaa tacccccggg tcaaaaaaat cgaaagtgat caaaacgctt ggggaacggg
     2161 caggggctcg acttcgcgat aattttaaaa atccatgtat aacccccctc ttataaccat
     2221 tttaaggcag gtgatgaaat ggagattata gttgatgaaa acttagtgct taaagaaaaa
     2281 gaaaggctgc aagtattata taaagacata cctagcaata aattaaaagt agttgatggt
     2341 ttaattattc aagcagcaag gctacgtgta atgcttgatt acatgtggga agacataaaa
     2401 gaaaaaggtg actatgattt atttactcaa tctgaaaagg cgccaccata tgaaagggaa
     2461 agaccagtag ccaaactatt taatgctaga gatgctgcat atcaaaaaat aatcaaacaa
     2521 ttatcggatt tattgcccga agagaaagaa gacacagaaa cgccatctga tgattaccta
     2581 tgattagtaa taaatacgtt gatgaatata taaatttgtg gaaacaagga aagataattt
     2641 taaataaaga aagaattgat ctctttaatt atctacaaaa acatatatat tcacgagatg
     2701 atgtatattt tgatgaacag aaaatcgagg attgtatcaa atttattgaa aaatggtatt
     2761 ttccaacatt accatttcaa aggtttatca tagctaatat atttcttata gataaaaata
     2821 cagatgaagc tttctttaca gaatttgcta ttttcatggg acgtggaggc gggaaaaacg
     2881 gtctaataag tgctattagt gattttcttt ctacgccctt acacggagtt aaagaatatc
     2941 acatctccat tgttgctaat agtgaagatc aagcaaaaac atcgtttgat gaaatcagaa
     3001 ccgttttaat ggataacaaa cgaaataaga cgggtaaaac gccaaaagct ccttatgaag
     3061 ttagtaaagc aaaaataata aaccgtgcaa ctaaatcggt tattcgatat aacacatcaa
     3121 acacaaaaac caaagacggt ggacgtgagg ggtgtgttat ttttgatgaa attcattatt
     3181 tctttggtcc tgaaatggta aacgtcaaac gtggtggatt aggtaaaaag aaaaatagaa
     3241 gaacgtttta tataagtact gatggttttg ttagagaggg ttatatcgat gcaatgaagc
     3301 acaaaattac aagtgtatta agtggcaagg ttaaaaatag tagattgttt gctttttatt
     3361 gtaagttaga cgatccaaaa gaagttgatg acagacagac gtgggaaaag gcgaacccaa
     3421 tgttacataa accgttatca gaatacgcta aaacactgct aagcacgatt gaagaagaat
     3481 ataacgattt accattcaac cgttcaaata agcctgaatt catgactaag cgaatgaatt
     3541 tgcctgaagt tgaccttgaa aaagtaatag caccatggaa agaaatacta gcgactaata
     3601 gagagatacc aaatttagat aatcaaatgt gtattggtgg tttagacttt gcaaatatcc
     3661 gagatttcgc aagtgtaggg ctactatttc gaaagaacga cgattatatt tggttaggac
     3721 attcttttgt aagacaaggg tttttggatg atgtcaaatt agagccacct attaaagaat
     3781 gggaaaaaat gggattattg accattgtag atgatgatgt cattgaaatt gaatatatag
     3841 ttgattggtt tttaaaggct agagaaaaat atgggcttga aaaagtcata gctgataatt
     3901 atagagctga tattgtaaga cgtgcgtttg aggatgctgg cataaaactt gaagtactta
     3961 gaaatccaaa agcaatacat ggattacttg caccacgtat cgatacaatg tttgcgaaac
     4021 ataacgtaat atatggagac aatcctttga tgcgttggtt tactaataat gttgcagtaa
     4081 aggttaaacc cgatggtaat aaagaatata ttaaaaaaga tgaaaataga agaaaaaccg
     4141 atgggttcat ggcttttgtt cacgcattat atagagcaga cgatatagta gacaaagaca
     4201 tgtctaaagc gcttgatgca ttaatgagta tagatttcta atagaggagg tgagacatga
     4261 gtattctaga aaagatattt aaaactagga aagatataac atatatgctt gatttagata
     4321 tgatagaaga tctatcacaa caagcgtatg tgaaacgttt agcgattgat agttgtattg
     4381 aatttgttgc gcgagctgtc gctcaaagtc attttaaagt attggaaggt aatagaattc
     4441 aaaagaatga tgtttactac aagttaaata taaaaccaaa tactgactta tcaagcgata
     4501 gtttttggca acaagttata tataaactaa tttatgataa cgaggtttta atcgtagtaa
     4561 gtgacagcaa agaattactt atcgcagata gcttttacag agaagagtac gctttgtatg
     4621 atgatatatt caaagatgta acggttaaag attatactta tcaacgtact ttcacaatgc
     4681 aagaggtcat atatttaaag tacaacaaca ataaagtgac acactttgta gaaagtctat
     4741 tcgaagatta cgggaaaata ttcggaagaa tgataggtgc acaattaaaa aactatcaaa
     4801 taagagggat tttgaaatct gcctctagcg catatgacga aaagaatata gaaaaattac
     4861 aagcgttcac aaataaatta ttcaatactt ttaataaaaa tcaactagca atcgcgcctt
     4921 tgatagaagg ttttgattat gaggaattat ctaatggtgg taagaatagt aacatgcctt
     4981 tttctgaatt gagtgagcta atgagagatg caataaaaaa tgttgcgttg atgattggta
     5041 tacctccagg tttgatttac ggagaaacag ctgatttgga aaagaacacg cttgtatttg
     5101 agaagttctg tttaacacct ttattaaaaa agattcagaa cgaattaaac gcgaaactca
     5161 taacacaaag catgtatttg aaagatacaa gaatagaaat tgtcggtgtg aataaaaaag
     5221 acccacttca atatgctgaa gcaattgaca aacttgtaag ttctggttca tttacaagga
     5281 atgaggtgcg gattatgtta ggtgaagaac catcagacaa tcctgaatta gacgaatacc
     5341 tgattactaa aaactacgaa aaagctaaca gtggtgaaaa tgatgaaaaa gaaaaagatg
     5401 aaaacacttt gaaaggtggt gatgaagatg aaagtggaga ttaaaggcgt catcgtttcc
     5461 aacgaagata aatgggttta cgaaatgctt ggtatggatt cgacttgtcc taaagatgtt
     5521 ttaacacaac tagaatttag tgatgaagat gttgatatta taattaactc aaatggtggt
     5581 aacctagtag ctggtagtga aatatataca catttaagag ctcataaagg caaagtgaat
     5641 gttcgtatca cagcaatagc agcaagtgcg gcatcgctta tcgcaatggc tggtgaccac
     5701 atcgaaatga gtccggttgc tagaatgatg attcacaatc cttcaagtat tgcgcaagga
     5761 gaagcgaaag atctaaatca tgctgcagaa acattagaac atgttggtca aataatggct
     5821 gaggcatatg cggttagagc tggtaaaaac aaacaagaac ttgtagaaat gatggctagg
     5881 gaaacgtggc taaatgctga tgaagccatt gaacaaggtt ttgcggatag taaaatgttt
     5941 gaaaacgaca atatgcaaat tgtagcaagc aatacacaag tgttatcgaa agatgtatta
     6001 aatcgtgtaa cagctttggt aagtaaaacg ccagaggtta acattgatat tgacgcaata
     6061 gcaaataaag taattgaaaa aataaatatg aaagaaaagg aatcagaaat cgatgttgca
     6121 gatagtaaag tatcagcaaa tggattttca agattccttt tttaatacaa aaaataggag
     6181 gtcataaaat gactataaat ttatcggaaa cattcgcaaa tgcgaaaaac gaatttatta
     6241 atgcagtaaa caacggtgaa ccgcaagaaa gacaaaatga attgtacggt gacatgatta
     6301 accaactatt tgaagaaact aaattacaag caaaagcaga agctgaaaga gtttctagtt
     6361 tacctaaatc agcacaatct ttgagtgcaa accaaagaag tttcttcatg gatatcaata
     6421 aaaacgttaa ctataaagaa gaaaaacttt tgccagaaga aacaattgat agaatttttg
     6481 aagatttgac gacgaatcat ccgttattag ctgatttagg tattaaaaac gctggtttgc
     6541 gtttgaagtt cttaaaatct gaaacttctg gcgtagccgt ttggggtaaa atctatggtg
     6601 aaattaaagg tcaattagat gctgcgttca gtgaagaaac agcaattcaa aataaattga
     6661 cagcgtttgt tgttttacca aaagatttaa atgattttgg tcctgcgtgg attgaaagat
     6721 ttgttcgtgt tcaaatcgaa gaagcatttg cagtggcgct tgaaactgcg ttcttaaaag
     6781 gtactggtaa agaccaacca atcggcttaa accgtcaagt acaaaaaggt gtatcggtaa
     6841 ctgagggtgc ttatccagag aaagaagaac aaggtacgct tacatttgct aatccgcgcg
     6901 ctacggttaa tgaattgatg caagtgttta aataccactc aactaacgag aaaggtaaat
     6961 cagtagcggt taaaggtaat gtaacaatgg ttgttaatcc gtccgatgct tttgaggttc
     7021 aagcacagta tacacattta aatgcaaatg gcgtatatgt tactgcttta ccatttaatt
     7081 tgaatgttat cgagtctaca gtccaagaag caggtaaggt tttaacgtac gttaaaggtt
     7141 tatatgatgg ttatttagct ggtggtatta atgttcagaa atttaaagaa acacttgcgt
     7201 tagatgatat ggatttatac actgcaaaac aatttgctta cggcaaagcg aaagataata
     7261 aagttgctgc tgtttggaaa ttagatttaa aaggacataa gccagcttta gaaggtaccg
     7321 aagaaacact ataaaatttt atgaggtgat aaaatggtga aatttaaagt tgttagagct
     7381 tttaaagaca tagagcacaa tcaacacaag tacaaagtag gggagttgta tccagctgaa
     7441 gggtataaca atcctcgtgt tgaattgttg acaaatcaaa tcaaaaataa gtacgacaaa
     7501 gtttatatcg tacctttaga taagctgaca aaacaagaat tattagaact atgcgaatca
     7561 ttacaaaaaa aagcgtctag ttcaatggtt aaaagtgaaa tcgtcgactt attgaatggt
     7621 gaagacaatg acgattgatg atttgcttgt caaatttaaa tcacttgaaa agattgacca
     7681 taattcagag gatgagtact taaagcagtt gttaaaaatg tcgtacgagc gtataaaaaa
     7741 tcagtgcgga gtttttgaat tagagaattt aataggtcaa gaattgatac ttatacgcgc
     7801 tagatatgct tatcaagatt tattagaaca cttcaacgat aattacagac ctgaaataat
     7861 agatttttcg ttatctctaa tggaggtatc agaagatgaa gaaagtgttt aaaaaaccta
     7921 gaattacaac taaacgttta aatactcgtg ttcattttta taagtatact gaaaataatg
     7981 gtccagaagc tggagaaaaa gaagaaaaat tattatatag ctgttgggcg agtattgatg
     8041 gtgtctggtt acgtgaatta gaacaagcta tctcaaacgg aacccaaaat gacattaaat
     8101 tgtatattcg tgatccgcaa ggtgattatt tacccagtga agaacattat cttgaaattg
     8161 aatcaagata tttcaaaaat cgtttgaata taaagcaagt atcaccagat ttggataata
     8221 aagactttat tatgattcgt ggaggatata gttcatgagt gtgaaagtga taggtgataa
     8281 agcattagaa agagaattag aaaaacgttt tggcataaaa gagatggtaa aagttcaaga
     8341 taaggcgtta atagctggtg ctaaggtaat tgttgaagaa gtaaaaaaac aactaaagcc
     8401 ctcaaaagat acgggagcat taattaatga ggtaagtttt agtaaacctg aatggataaa
     8461 cggaaaacgt acaattactg ttcattggcg aggttctaaa gaccgttata aaatcgtaca
     8521 tttaattgaa tatggacacg ttcaaaaaga aacaggtaaa tttatcaaac ctaaagctat
     8581 gggcggtgtt aatagagcaa taagacaagg gcaaaataag tattttgaga cgctaaaaag
     8641 ggagttgaaa aaattgtgat tgatattttg tacaaagttc atgaagtgat tagtcaagac
     8701 agaattatta gagagcacgt aaatatcaat aatattaagt tcaataaata ccctaatgta
     8761 aaagatactg atgtaccttt tattgttatt gacgatatcg acgacccaat acctacaact
     8821 tatactgacg gagatgagtg tgcatatagt tatattgtcc aaatagatgt ttttgttaag
     8881 tacaatgatg aatataatgc gagaatcata agaaataaga tatctaatcg tattcaaaag
     8941 ttattatggt ctgaactaaa aatgggaaat gtttcaaatg gaaaaccgga atatatagaa
     9001 gaatttaaaa catatagaag ctctcgcgtt tacgagggca ttttttataa ggaggaaaat
     9061 taaatggcag taaaacatgc aagtgcgcca aaggcgtata ttaacattac tggtttaggt
     9121 ttcgctaaat taacgaaaga aggcgcggaa ttaaaatata gtgatattac aaaaacaaga
     9181 ggattacaaa aaattggtgt tgaaactggt ggagaactaa aaacagctta tgctgatggc
     9241 ggtccaattg aatcagggaa tacagacgga gaaggtaaaa tctcattaca aatgcatgcg
     9301 ttccctaaag agattcgcaa aattgttttt aatgaagatt atgatgaaga tggcgtttac
     9361 gaagagaaac aaggtaaaca aaacaattac gtagctgtat ggttcagaca agagcgtaga
     9421 gacggtacat ttagaacagt tttattacct aaagttatgt ttacaaatcc taaaatcgat
     9481 ggagaaacgg ctgagaaaga ttgggatttc tcaagtgaag aggttgaagg tgaggcactt
     9541 ttccctttag ttgataataa aaagtctgta cgtaaatata tctttgactc agctaacatg
     9601 acaaatcatg gtggcgacgg tgaaaaaggc gaagaggctt tcttaaagaa aattttaggc
     9661 gaagaatata ctggaaacgt gacagaggat aacgaagaaa ctttgtaacg aaaccggctt
     9721 catcggaaac tgcggtaaag tcggttaata taccagatag cattaaaaca cttaaagttg
     9781 gcgacacata cgatttaaat gttgtagtag agccatctaa tcaaagtaag ttattgaaat
     9841 acacaacaga tcaaacgaat attgtatcaa tcaatagaga tggtcaagtt actgcggaag
     9901 cacaaggcat tgctacggtt aaagcaacag ttggtaatat gagtgacact ataacaataa
     9961 atgtagaagc ataagagggg gcaacccctc tattttattt gaaaataagg agagtattat
    10021 aaaatggcaa aattaaaacg taacattatt caattagtag aagacccgaa agcaaatgaa
    10081 attaaattac aaacgtactt aacaccacac ttcatttcat ttgaaattgt atacgaagca
    10141 atggatttaa tcgatgatat tgaggacgaa aatagcacga tgaaaccaag agaaatcgct
    10201 gacagattga tggatatggt tgtaaaaatt tacgataacc aattcacagt taaagactta
    10261 aaagaacgta tgcatgcacc tgatggaatg aatgcacttc gtgaacaagt aattttcatt
    10321 actcaaggtc agcaaactga ggaaactaga aattttatcc agaacatgaa ataaagcctg
    10381 aagatttaac atataaagca atgttgaaaa atatggatac tctcatgatg gacttaattg
    10441 aaaatggtaa agacgctaac gaagttttaa aaatgccatt tcattatgta ctttccatat
    10501 atcaaaataa aaacaatgac atttctgaag aaaaagcaga ggctttaatt gatgcgtttt
    10561 aaccttaacc gtttggttag ggttattttt ttgaactttt ttagaaagga ggtaaaaaat
    10621 gggagaaaga ataaaaggtt tatctatagg tttggatttg gattcagcaa atttaaatag
    10681 atcacttaca gaaattaaac gaaactttag aaccttaaat tcagacttaa agttgactgg
    10741 aaacaacttt aaatatactg agaaatcaac tgatagttat aaacaacgaa tcaaagagtt
    10801 agatggcaca attgcaggtt ataagaaaaa cattgatgat ttagcgaagc aatatgacaa
    10861 ggtatctcaa gaacagggtg aaaatagtac aaaagctcag aatttaagac aagaatataa
    10921 caaacaagca aatgagctga attttttaga aaaagaacta gaaaaaacaa cagctgagtt
    10981 tgaagagttc aaaaaagccc aagttgaagc tcaaagaatg gcagaaagtg gctgggggaa
    11041 aaccagtaaa atttttgaaa gtatgggacc taaattaaca aaaatgggtg atggtttaaa
    11101 atctattggt aaaggtatga tgattggtgt taccgcacct gttttaggta ttgcagcagc
    11161 atcaggaaaa gcttttgcag aagttgataa aggtttagat acagttaccc aagcaacagg
    11221 agcaaccggc ggagagctta agaagttgca gaattcattt aaagatgttt atggcaactt
    11281 tccagcagac gctgagactg taggcggtgt tttaggggaa gttaatacaa ggttaggttt
    11341 tacaggtaaa gaacttgaaa atgccacaga gtcattcttg aaattcagtc atataacagg
    11401 ttctgacggt gtgcaagccg tacagttaat tacccgtgca atgggcgatg caggtatcga
    11461 agcaagtgaa tatcaaagtg ttttggatat ggtagcaaaa gcggcgcaag ctagtgggat
    11521 aagtgttgat acattagctg atagtattac taaatacggc gctccaatga gagctatggg
    11581 ctttgagatg aaagaatcaa ttgctttatt ctctcaatgg gaaaagtcag gcgttaatac
    11641 tgaaatagca ttcagtggtt tgaaaaaagc tatatcaaat tggggtaaag ctggtaaaaa
    11701 cccaagagaa gaatttaaga agacattagc agaaattgaa aggacaccgg atatagctag
    11761 cgcaacaagt ttagcgattg aagcatttgg tgcaaaagca ggtcctgatt tagcagatgc
    11821 tattaaaggc ggtcgcttta gttaccaaga gttcttaaaa actatcgaag attcgcaagg
    11881 aacggtcaat caaacattta aagattctga aagtggctcc gaaagattta aagtagcaat
    11941 gaataaactt aaattagtag gtgctgatgt atgggcttct attgaaagtg cgtttgctcc
    12001 agtaatggaa gaactaatca aaaagctatc tatagcggtt gattggtttt caagtttaag
    12061 tgatggatct aaaaggtcga ttgttatatt cggtggtatt gctgctgcaa ttggtcctgt
    12121 agtttttgga ttaggtgtat tcataagcac agttggcaac gcagtaactg tattagctcc
    12181 attattagct agtattgcaa aggctgacgg attgattagt tttttatcaa ctaaagtacc
    12241 tattttagga acagtcttca cagcattaac tggtccaatt ggtatcgtgt taggtgtact
    12301 ggctggttta gcagtcgcat ttacaatagc ttataagaaa tctgaaacat tcagaaattt
    12361 tgttaatggt gcaattaaca gtgttaaaca aacgtttagt aatttcattc aatttatcca
    12421 acctttcatt gattccgtta aaaacatctt taaacaagcg gtttcagcaa tagttgattt
    12481 tgctaaagat atttggagtc aaatcaatgg attctttaat gaaaatggaa tttccattgt
    12541 tcaagcactt caaaatatat gcaactttat taaagcgata tttgaattta ttttaaattt
    12601 tgtaattaaa ccaattatgt tcgcaatctg gcaagtgatg caatttattt ggccggcggt
    12661 taaagccttg attgtcagta cttgggagaa tataaaagga gtaatacaag gagctttaaa
    12721 tatcatactt ggctttatta agttcttttc aagtttattc actggtaatt ggcgaggtgt
    12781 ttgggacggt attgtgatga tactaaaagg cactgtgcag ttaatttgga atttaataca
    12841 actgtggttt gtaggtaaga ttctaggtgt tgttagatac tttggtggat tacttaaagg
    12901 tttaataact attatatggg ttgctataat aggcgttttc aagaaatcat tatcggcaat
    12961 ttggaatgcg acaaaaagta tttttggatt cttatttaat agtgtcaaat caattttcac
    13021 gaatatgaaa aattggttat ctaatacttg gagtagtatc cgtacgaata cgataggaaa
    13081 agcgcagtca ttatttagtg gcgtcaaatc aaaatttact aatttatgga atgcgacgaa
    13141 agaaattttt agtaatttaa gaaattggat gtcaaatatt tggaattcca ttaaagataa
    13201 tacggtagga attgctagcc gtttatggag taaggtacgt ggaattttta caaatatgcg
    13261 tgacggctta caaagtatta tcagcaaaat taaaagtcat atcggcggta tggtagatgc
    13321 tattaaaaaa ggacttaata aattaatcga cggtttaaac tgggtcggtg gtaagttggg
    13381 catggataaa atacctaagt tacatactgg tacagagcac acacatacta ctacaagatt
    13441 agttaagaac ggtaagattg cacgtgacac attcgctaca gttggagata agggacacgg
    13501 aaatggtcca aatggtttta gaaacgaaat gattgaattc cctaatggta aacgtgtaat
    13561 cacaccaaat acagatacta ctgcttattt acctaaaggc tcaaaagtat ataacggtgc
    13621 acaaacttat tcaatgttaa acggaactct tccaagattt agtttaggta ctatgtggaa
    13681 agatattaag tccggtgcat catcagcatt taactggaca aaagatcaaa taggtaaagg
    13741 taccaaatgg cttggcgata aagttggcga tgttttagat tttattgaaa atccaggaaa
    13801 acttttaaat tatatacttg aagcttttgg aattgatttc aattctttaa ctaaaggaat
    13861 gggaattgca ggcgacataa caaaagctgc atggtctaag attaagaaaa gtgctactga
    13921 ttggataaaa gaaaatttag aagctatggg cggtggcgat ttagtcggcg gaatattaga
    13981 ccctgacaaa attaattatc attatggacg taccgcagct tataccgctg caactggaag
    14041 accatttcat gaaggtgtcg attttccatt tgtatatcaa gaagttagaa cgcctatggg
    14101 tggtagactt acaagaatgc cgtttatgtc tggtggttat ggtaactatg taaaaattac
    14161 tagtggcgtt atcgatatgc tatttgcgca tttgaaaaac tttagcaaat caccacctag
    14221 tggcacgatg gtaaagcccg gcgatgttgt tggtttaact ggtaataccg gatttagtac
    14281 aggaccacac ttacattttg aaatgaggag aaacggacgc cattttgacc ctgaaccata
    14341 tttaagaaat gcaaagaaaa aaggtaggtt atcaattggt ggcggtgatg ctacttctgg
    14401 aagtggtgca acttatgcca gccgagtaat ccgacaagcg caaagtattt taggaggacg
    14461 ttataaaggt aagtggattc atgaccagat gatgcgagtt gcaaagcgtg aaagcaacta
    14521 tcaatcaaat gcagtgaata attgggatat taatgctcaa agaggagacc cgtctagagg
    14581 attattccaa attatcggct caacttttag agctaacgct aaacgagggt acactaatta
    14641 taataatcca gtacatcaag gtatctcagc aatgcagtac attgttagac gatatggttg
    14701 gggtggtttt aaacgtgctg gtgattacgc atatgctaca ggtggaaaag tttttgatgg
    14761 ttggtataac ttaggtgaag acggtcatcc agaatggatt attccaacag atccagctcg
    14821 tagaaatgat gcaatgaaga ttttgcatta tgcagcagca gaagtaagag ggaaaaaagc
    14881 gagtaaaaat aagcgtccta gtcaattgtc tagtgtaaat gggtttgatg acccaagctt
    14941 attattgaaa atgattgaac aacagcaaca acaaatagct ttattactga aaatagcgca
    15001 atccaacgat gtgattgcag ataaagatta tcagccgatt attgacgaat acgcttttga
    15061 taaaaaggtg aacgcgtcta tagaaaagcg agaaaggcaa gaatcaacaa aagtaaagtt
    15121 tagaaaagga ggaattgcta ttcaatgata gacactatta aagtgaacaa caaaacaatt
    15181 ccttggttgt atgtcgaaag agggtttgaa ataccctctt ttaattatgt tttaaaaaca
    15241 gaaaatgtag atggacgttc gggggctata tataaagggc gtaggcttga atcttatagt
    15301 tttgatatac ctttagtggt acgtaatgac tatttatctc acaacggcat taaaacatat
    15361 gatgacgtct tgaatgaatt agtaaagttt tttaactacg aggaacaagt taaattacaa
    15421 ttcaaatcta aagattggta ctggaacgct tattttgaag gaccaataaa gctgcacaaa
    15481 gaatttacaa tacctgttaa gttcactatc aaagtagtac taacagaccc ttacaaatat
    15541 tcagtaacag gaaataaaaa tactgcgatt tcagaccaag tttcagttgt aaatagtggg
    15601 actgctgaca ctcctttaat tgttgaagcc cgagcaatta aaccatctag ttactttatg
    15661 attactaaaa atgatgaaga ttattttatg gttggtgatg atgaggtaac caaagaagtt
    15721 aaggattaca tgcctcctgt ttatcatagt gagtttcgtg atttcaaagg ttggactaag
    15781 atgattactg aagatattcc aagtaatgac ttaggtggta aggtcggcgg tgactttgtg
    15841 atatccaatc ttggcgaagg atataaagca actaattttc ctgatgcaaa aggttgggtt
    15901 ggtgctggca cgaaacgagg gctccctaaa gcgatgacag attttcaaat tacctataaa
    15961 tgtattgttg aacaaaaagg taaaggtgcc ggaagaacag cacaacatat ttatgatagt
    16021 gatggtaagt tacttgcttc tattggttat gaaaataaat atcatgatag aaaaatagga
    16081 catattgttg ttacgttgta taaccaaaaa ggagacccca aaaagatata cgactatcag
    16141 aataaaccga taatgtataa cttggacaga atcgttgttt atatgcggct cagaagagta
    16201 ggtaataaat tttctattaa aacttggaaa tttgatcaca ttaaagaccc agatagacgt
    16261 aaacctattg atatggatga gaaagagtgg atagatggcg gtaagtttta tcagcgtcca
    16321 gcttctatca tagctatcta tagtgcgaag tataacggtt ataagtggat ggagatgaat
    16381 ggattaggtt cattcaatac ggagattcta ccgaaaccga aaggcgcaag ggatgtcatt
    16441 atacaaaaag gtgatttagt gaaaatagat atgcaagcaa aaagtgttgt catcaatgag
    16501 gaaccaatgt tgagcgagaa atcgtttgga agtaattatt tcaatgttga ttctgggtac
    16561 agtgaattaa tcatacaacc tgaaaacgtc tttgatacga cggttaaatg gcaagataga
    16621 tatttataga aaggagatga gagtgtgata catgttttag attttaacga caagattata
    16681 gatttccttt ctactgatga cccttcctta gttagagcga ttcataaacg taatgttaat
    16741 gacaattcag aaatgcttga actgctcata tcatcagaaa gagctgaaaa gttccgtgaa
    16801 cgacatcgtg ttattataag ggattcaaac aaacaatggc gtgaatttat tattaactgg
    16861 gttcaagata cgatggacgg ctacacagag atagaatgta tagcgtctta tcttgctgat
    16921 ataacaacag ctaaaccgta tgcaccagga aaatttgaga aaaagacaac ttcagaagca
    16981 ttgaaagatg tgttgagcga tacaggttgg gaagtttctg aacaaaccga atacgatggc
    17041 ttacgtacta cgtcatggac ttcttatcaa actagatatg aagttttaaa gcaattatgt
    17101 acaacctata aaatggtttt agatttttat attgagctta gctctaatac cgtcaaaggt
    17161 agatatgtag tactcaaaaa gaaaaacagc ttattcaaag gtaaagaaat tgaatatggt
    17221 aaagatttag tcgggttaac taggaagatt gatatgtcag aaatcaaaac agcattaatt
    17281 gctgtgggac ctgaaaatga caaagggaag cgtttagagc tagttgtgac agatgacgaa
    17341 gcgcaaagtc aattcaacct acctatgcgc tatatttggg ggatatatga accacaatca
    17401 gatgatcaaa atatgaatga aacacgatta agttctttag ccaaaacaga gttaaataaa
    17461 cgtaagtcgg cagttatgtc atatgagatt acttctactg atttggaagt tacgtatccg
    17521 cacgagatta tatcaattgg cgatacagtc agagtaaaac atagagattt taacccgcca
    17581 ttgtatgtag aggcagaagt tattgctgaa gaatataaca taatttcaga aaatagcaca
    17641 tatacattcg gtcaacctaa agagttcaaa gaatcagaat tacgagaaga gtttaacaag
    17701 cgattaaacc taatacacca aaaattaaac gacaatatta gcaatatcaa tactatagta
    17761 aaagatgttg tagatggtga attagaatac tttgaacgca aaattcataa aagtgataca
    17821 ccgccagaaa atccagtcaa tgatatgctt tggtatgata caagtaaccc tgatgttgct
    17881 gtcttgcgta gatattggaa tggtcgatgg attgaagaaa caccaaatga tgttgaaaaa
    17941 ttaggtggta taacaagaga gaaagcgcta ttcagtgaat taaacaatat atttattaat
    18001 ttatctatac aacacgctag tcttttgtca gaagctacag aattactgaa tagcgagtac
    18061 ttagtagata atgatttgaa agcggactta caagcaagtt tagacgctgt gattgatgtt
    18121 tataatcaaa ttaaaaataa tttagaatct atgacacccg aaactgcaac gattggtcgg
    18181 ttggtagata caaaaacttt atttcttgag tatagaaaga aattacaaga tgtttataca
    18241 gatgtagaag atgtcaaaat cgccatttca gatagattta aattattaca gtcacaatac
    18301 actgatgaaa aatataaaga agcgttggaa ataatagcaa caaaatttgg tttaacggtg
    18361 aatgaagatt tgcagttagt cggagaacct aatgttgtta aatcagctat tgaagcagct
    18421 agagaatcca caaaagaaca attacgtgac tatgtaaaaa catcggacta taaaacagac
    18481 aaagacggta ttgttgaacg tttagatact gctgaagctg agagaacgac tttaaaaggt
    18541 gaaatcaaag ataaagttac gttaaacgaa tatcgaaacg gattggaaga acaaaaacaa
    18601 tatactgatg accagttaag tgatttgtcc aataatcctg agattaaagc aagtattgaa
    18661 caagcaaatc aagaagcgca agaagcttta aaatcataca ttgatgctca agatgatctt
    18721 aaagagaagg aatcgcaagc gtatgctgat ggtaaaattt cggaagaaga gcaacgcgct
    18781 atacaagatg ctcaagctaa acttgaagag gcaaaacaaa acgcagaact aaaggctaga
    18841 aacgctgaaa agaaagctaa tgcttataca gacaacaagg tcaaagaaag cacagatgca
    18901 cagaggaaaa cattgactcg ctatggttct caaattatac aaaatggtaa ggaaatcaaa
    18961 ttaagaacta caaaagaaga gtttaatgct tctaaaagaa cactatcaag agtgttagca
    19021 gacatcactg taaatgctat gaaaggcatc tatttaaggt atgacgaaaa tggggcgatt
    19081 acttcacata ctattgataa agatggcgtg aaaattagtg gcgataaagt tgatataaca
    19141 gcgaatagag aatttaatgt agtcgcaaat aatattaata acaaagttgg taaaaatgac
    19201 attgttaata gcctaaactt atcaaatgaa ggtcttgaca tcaatgtgaa tagaattggt
    19261 attaaaggcg gaaatgctaa ccgttatgta caagttcaaa atgattttat tgaacttggc
    19321 ggaatcgtac aacgaacttg gaaaggcaaa cgatcaaccg atgatatatt cacacgtctt
    19381 aaagatggac atctaaggtt tagaaataat accgcaggcg gttcacttta tatgtcacat
    19441 tttggtattt caacatatat tgatggagaa ggcgaagacg gaggttcatc cggtactatt
    19501 caatggtggg ataaaactta cagtgatagc ggtatgaatg gcataacaat caattcttat
    19561 ggcggtgtag tcgctttaac atctgactac aaccgaatta ttatcgattc atatgcttca
    19621 gctaatattg aaagtagaga agcaccgata tatttatctc cgaacaccaa aaataaacct
    19681 ggtttaaacc gattcgcatt cacattatca aacgctgata gtgcatacga aactgacggt
    19741 tatatcatgt ttggttcaga tgaaaactat aagtacggtg ctggattaag attttctaaa
    19801 cgtagcaata aaggattggt tcaagtcgtt aatggtgact atgctacagg cggagacact
    19861 acaattgagt caggtatggg caaattcaac atagttaaac gaagagatgg aaatagttac
    19921 gttagcattc aaagttatga tttattggcg gtaggttctg ataatgctgg cgatagagtc
    19981 gcttctaatt ctatttataa gcgtacttat tcagcacctg ctaacttaca cattacttct
    20041 gctggaacaa ttgggcgtgc tacttctgcc aaaaagtata aaatttcaat cgaaaatcaa
    20101 tacatcaatg aagacgatca gttcagtcat tcaaaagaga ttttaaagct tccaattcgt
    20161 acatggtttg acaaatatga atcggaaata atggctaaag aattggaaag tggtaaaaag
    20221 ttatctgatg atacttttaa acttagtcga catactggct taatagcgga agaggttgaa
    20281 gaattaggat ttaatgaatt tgttatttat gatgacaacg gagaaatcga aggtatcgca
    20341 tacgatagac tttgggttca tttaatacct attattaaaa accagcaatc aaaaatcgaa
    20401 aaactggagg aattaataaa tgaatgatag caatcaaggt ttacaagcca atccacaata
    20461 tacaattcac tatttatcgc aagaaatcac aagactaaca caagaaaatg caatgttaaa
    20521 agcatatata caagaacaaa atgaaaaaag caaaagtgct gaggaagagt aatccttggc
    20581 actattttta tacaaaaatt taaggaggtc atttaatatg gcaaatgaaa ttatcaaaaa
    20641 aacagagaga tttattttag tacaaattga caaagaggga acagagcgcg ttttgtatca
    20701 agattttgta ggcagtttta caacgtccga ttcagcaagt tatgcacaag attttaaatc
    20761 tgaggaaaac gctaaaaaga ttgctgaaac tttaaatctt ttatatcaat taacaggcaa
    20821 tcaaaacggt gtgaaagttg tgaaagaagt tgtggataga actgacttgt catctgataa
    20881 atcagttgat agcgaaacaa tgtaactata ctaagttatg agcattacgc tcatagcttt
    20941 cttagaaagt aggtgtagtt ttggatgata ttcagaaaat aaaaaaagag ctttctgaat
    21001 tagttgaacg tgttgatgat gttgaaatac tagcaaacga aacagctgat catgtgcttg
    21061 aacttagaga ggaacataag caacatcata atgaactaag agaatctcat aaagaactta
    21121 aagataagca agataaagtt gtagatgaga atttagagca aacaaagata ttaaacagaa
    21181 ttgaagaaag atatcaaacg caagtagatg ttgcgcaaaa aaatgaagaa aagacactcg
    21241 cccaaaataa atggctcgta ggtgccatat gggcgcttgt aacaattgtt atgattgcag
    21301 tcattactgc atcaattact gcgttattac cttaagggag gtggacataa tgagttgggc
    21361 aagatggtta tcatgttatt tgtatggtcg taaatgtaaa taatgttttt ggtcagtgca
    21421 tcggcactgg ctttttattt tgattgaaaa gaggtacgta catggtatta cacagctcaa
    21481 aagacaggaa gcatactgca agtgaagttg ggaagtgttg ttaataccaa gtaagtaaga
    21541 tatctgaaat gtataataga gtaaaaatga aatcttttta ttatagacaa atataaaaag
    21601 tgtatagtaa tatatgtatg tataattaaa tgataatcat ttcataatta ttgtatataa
    21661 ctaaataact acttaacaaa aataattatg ctttagaggt gagcaaaatg aaaaaaacag
    21721 catttacatt acttttattc attgccctaa cgttgacaac aagtccactt gtaaatggta
    21781 gcgagaaaag cgaagaaata aatgaaaaag atttgcgaaa aaagtctgaa ttgcagggaa
    21841 cagctttagg caatcttaaa caaatctatt attacaatga aaaagctaaa actgaaaata
    21901 aagagagtca cgatcaattt ttacagcata ctatattgtt taaaggcttt tttacagatc
    21961 attcgtggta taacgattta ttagtagatt ttgattcaaa ggatattgtt gataaatata
    22021 aagggaaaaa agtagacttg tatggtgctt attatggtta tcaatgtgcg ggtggtacac
    22081 caaacaaaac agcttgtatg tatggtggtg taacgttaca tgataataat cgattgaccg
    22141 aagagaaaaa agtgccgatc aatttatggc tagacggtaa acaaaataca gtacctttgg
    22201 aaacggttaa aacgaataag aaaaatgtaa ctgttcagga gttggatctt caagcaagac
    22261 gttatttaca ggaaaaatat aatttatata actctgatgt ttttgatggg aaggttcaga
    22321 ggggattaat cgtgtttcat acttctacag aaccttcggt taattacgat ttatttggtg
    22381 ctcaaggaca gtattcaaat acactattaa gaatatatag agataataaa acgattaact
    22441 ctgaaaacat gcatattgat atatatttat atacaagtta aacatggtag ttttgaccac
    22501 gtaatgttca gattattatg aaccgagaat aatctaaaag tttacaagca gtaaaaaaag
    22561 tatatgtgct ataatatgct ttgagcaagt tggatagatg gtggctatct gagtataagg
    22621 aggtggtgcc tatggtggca ttactgaaat ctttagaaag gagacgccta atgattacaa
    22681 ttagtaccat gttgcagttt ggtttattcc ttattgcatt gataggtcta gtaatcaagc
    22741 ttattgaatt aagcaataaa aaataaccat cgctaacttt ggctggtttc gatggttaaa
    22801 tggttattaa tttaatcttt aatctaaaat agccaccgtc tttttaacgg gctcactagg
    22861 gtaacatgtt tgcgcatgtt gccctttttc tatatataaa ttaacacacc ataatataaa
    22921 tatcaaatag acggcttatt ggtcgtcttt ttattttgga taaaaggaga taagaatatg
    22981 attaattgga aaattagaat gaaacaaaaa tcattttggg tagcgatatt gtcagctatc
    23041 tttttatttg ctcaaaacat cgccaaagct attgggtatg atattcaagt ttatacagag
    23101 caattaacag acggtttaaa cgctatatta ggatttttag tattaactgg tgtgattcaa
    23161 gacccgacta ctaaaggtat aggtgatagc caccaagctt tagaatatga agaaccaaga
    23221 agaaaatact aggaggtaaa ataatgaaaa catacagtga agcaagagca aggttacgtt
    23281 ggtatcaagg tagatatatt gattttgacg gttggtatgg ttaccaatgt gcagatttag
    23341 cagttgatta catttattgg ttgttagaaa ttagaatgtg gggaaatgca aaagatgcaa
    23401 tcaataacga ttttaaaaac atggcaacag tatatgaaaa cacaccatcg tttgttccac
    23461 aaataggtga tgtggctgta tttaccaaag gaatatataa acaatacggt catattggtt
    23521 tagtgtttaa tggtggtaat acaaatcaat ttttaatttt ggaacagaac tatgacggta
    23581 acgcaaatac gcctgcaaag ttacgttggg ataattatta cggctgtact cactttatta
    23641 gacctaagta taaaagtgag ggcttaatga ataagatcac aaataaagtt aaaccacctg
    23701 ctcaaaaagc agtcggtaaa tctgcaagta aaataacagt tggaagtaaa gcgccttata
    23761 accttaaatg gtcaaaaggt gcttatttta atgcgaaaat cgacggctta ggtgctactt
    23821 cagccactag atacggtgat aatcgtacta actatagatt cgatgttgga caggctgtat
    23881 acgcgcctgg aacattaata tatgtgtttg aaattataga tggttggtgt cgcatttatt
    23941 ggaacaatca taatgagtgg atatggcatg agagattgat tgtgaaagaa gtgttttaat
    24001 tcttaggtta aaatgttaaa tatttgttaa ttatttttta atgtaagttt agtttctttt
    24061 aatattttat tgatttttaa tattttctca atataaaatg aagttgttga tatttatcat
    24121 cttaaataag ggtgttagct ataaaaagag ataaataaaa acaaatatat tatatttgga
    24181 ggaagcgcca tgctcaaaag aagtttatta tttttaactg ttttattgtt attattctca
    24241 ttttcttcaa ttactaatga ggtaagtgca tcaagttcat tcgacaaagg aaaatataaa
    24301 aaaggcgatg acgcgagtta ttttgaacca acaggcccgt atttgatggt aaatgtgact
    24361 ggagttgatg gtaaaggaaa tgaattgcta tcccctcatt atgtcgagtt tcctattaaa
    24421 cctgggacta cacttacaaa agaaaaaatt gaatactatg tcgaatgggc attagatgcg
    24481 acagcatata aagagtttag agtagttgaa ttagatccaa gcgcaaagat cgaagtcact
    24541 tattatgata agaataagaa aaaagaagaa acgaagtctt tccctataac agaaaaaggt
    24601 tttgttgtcc cagatttatc agagcatatt aaaaaccctg gattcaactt aattacaaag
    24661 gttgttatag aaaagaaata aaacaaaata gttgtttatt atagaaagca atgtcttgat
    24721 tgaatatgtg tagtgaaaat tatctttcat caaattctca ttcatgcacg aatggttctt
    24781 ccccacctaa tcagatatta ggtgacttat ggggagaaat cagttaggat gaaaaagtgg
    24841 ataatccttt tttaggcagg tacttcggta cttgcctatt tttttatgtt ataatctttc
    24901 tagacgtatt caaaggacgt ctttttagat tgtatgttat agctagcttt cgggctagtt
    24961 ttttgctatg atgtgttaca catgcatcaa ctatttacat ctatccttgt tcacccaagc
    25021 atgtcactgg gtgttttttt cttatgatag agagcatagt tttcatacta ctcccccgta
    25081 gtatatatga ctttagcatt cccgtataat agtttacggg gtgcttttta tgttataatt
    25141 aagtgtatat agtaggagtg aactatatag cctgttaagt ggcctagtaa cctaacactt
    25201 atcctgcaat tgatatcctt tttgcccttc actcgataca tatatctcaa caacatagaa
    25261 atattacagt cgctacaccg catcttaaat ggtgtggtta tttttattgg aagtgtgtat
    25321 caggtatcag taatgttaaa acaccagcta aaaatgaaaa gaattcacca gtgccagcag
    25381 gttatacact cgataaaaac aatgtaccgt ataaaaaaga gactggttat tacacagttg
    25441 ccaatgttaa aggtaataac gtgagggatg gctattcaac taattcaaga attacaggtg
    25501 tattacccaa taacgcaacg atcaaatatg acggcgcata ttgcattaat ggctatagat
    25561 ggattactta tattgctaat aatggacaac gttgttatat agcgacagga gaggtagaca
    25621 aggcaggtaa tagaataagt agttttggta attttagcgc actttgaaaa aaagtgtgta
    25681 aagtttcata tgaagttaat taatttatta tagaatagtt tgaaattatg ctataatcat
    25741 tttagacaca gcaatgtgtt caaattttca tctattcata agctagcctt cgggctagtt
    25801 tttttgtgct atatatttgt tttaattaaa taaaattaga taatgcaata gtagccattt
    25861 tatgttaata ttaccttggg cgttttcaag gagcgccttt cattttttat gtattgctcc
    25921 ccttcgggct agtatattaa atttattttt gcgctttcca aatcaatgta tatgtgttat
    25981 attgtttatg ggaagtaggt aagcatttcg gtgcttacct ttttttgttt ttctataaat
    26041 acaataaggt atgtcaattt gataatttat taattttcat ttaataagaa gatctatata
    26101 gttaatgaat aattaatgta ctttttttta gttagtcatt aaaataaatt agtactaatt
    26161 actaaggaga ataaaaaatg aaaattagaa aatctatact tgcgggaact ttagcaatcg
    26221 ttttagcatc accactagta actaatctag ataaaaatga ggcacaagct agcacaagct
    26281 tgccaacatc gaatgaatat caaaacgaaa agttagctaa tgaattaaaa tcgttattag
    26341 atgaactaaa tgttaatgaa ttagctactg gaagtttaaa cacttattat aagcgaacta
    26401 taaaaatttc aggtcaaaaa gcaatgtatg ctcttaagtc aaaagacttt aagaaaatgt
    26461 cagaagcaaa atatcaactt caaaagattt ataatgaaat tgacgaagca ctaaaaagta
    26521 aatattaaaa aaaccacccg taaaagggtg gttttaattt tctagataat ataaaagtgt
    26581 tcataaataa aacagtatag gtaaacaata aagtattgaa aaaagtaagt ttaatatgaa
    26641 aattgttaaa tgaacgacat cttttgtttt tataaatatc aagaaaataa tcaaactcaa
    26701 aataaataac gtaactgtag tcataggcgt ccatacataa tcagcattag tcattaagaa
    26761 tggtgcggcc attatgaaaa aatttataat gcagatgaaa tagacaatta gactataaat
    26821 taggtaaata acaatacaca cccttcataa ataaataatt taaatcctat atattttaac
    26881 aaaagtaaaa cacagaagtg tagaaaataa aaaatattgg taaataaaat caataagttt
    26941 aaccaatatg ttgctcgctt cataccgtat attgcaacaa aaattccgat caagaaaaat
    27001 atagccccta tgataaaaca gaaatccgat gctgaattat taaaaaatga ggtgtttaga
    27061 gttagaaaat gagttaatga gttgactata actaataaga tattaattat atttgtatgg
    27121 ttcttcacat gatacttcca agtaaaaaaa tctaattaat aaagtgaatg cttgatgaac
    27181 aagcagttat tccaaacaga atcaataaga aaagtagaat caacatgcta atgccccata
    27241 aacaaccctt ttcactttca ctattattaa tttcttgact tcttttaaag atattattac
    27301 ttttacattc tttagttgtt ttaaatttca cgtttttatt acttcctttt gtttaaaagt
    27361 ttacaatgaa tttttga
//
LOCUS       DAPDIM010000037        26549 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000037 DAPDIM010000000
VERSION     DAPDIM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 26549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26549
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.037"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            94..852
                     /gene="nagB"
                     /locus_tag="RFE25_001641"
     CDS             94..852
                     /gene="nagB"
                     /locus_tag="RFE25_001641"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDU2816698.1"
                     /translation="MKVLNLGSKKQASFYVACELYKEMAFNQHCKLGLATGGTMTDLY
                     EQLVKLLNKNQLNVDNVSTFNLDEYVGLTASHPQSYHYYMDDMLFKQYPYFNRKNIHI
                     PNGDADDMNAEASKYNDVLEQQGQRDIQILGIGENGHIGFNEPGTPFDSVTHIVDLTE
                     STIKANSRYFKNEDDVPKQAISMGLANILQAKRIILLAFGEKKRAAITHLLNQEISVD
                     VPATLLHKHPNVEIYLDDEACPKNVAKIHVDEMD"
     gene            929..1561
                     /gene="hxlA"
                     /locus_tag="RFE25_001642"
     CDS             929..1561
                     /gene="hxlA"
                     /locus_tag="RFE25_001642"
                     /EC_number="4.1.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hexulose-6-phosphate synthase"
                     /protein_id="HDU2816699.1"
                     /translation="MELQLAIDLLNKEDAAELANKVKDYVDIVEIGTPIIYNEGLPAV
                     KHMADNISNVKVLADMKIMDAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKN
                     NKQLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKKS
                     KVAVAGGIKPDTIKDIVAESPDLVIVGGGIANADDPVEAAKQCRAAIEGK"
     gene            1563..2111
                     /gene="hxlB"
                     /locus_tag="RFE25_001643"
     CDS             1563..2111
                     /gene="hxlB"
                     /locus_tag="RFE25_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499126.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HDU2816700.1"
                     /translation="MAKFSDYQLILDELKMTLSHVEADEFSTFASKILHAEHIFVAGK
                     GRSGFVANSFAMRLNQLGKQAHVVGESTTPAIKSNDVFVIISGSGSTEHLRLLADKAK
                     SVGADIVLITTNKDSAIGNLAGTNIVLPAGTKYDEQGSAQPLGSLFEQASQLFLDSVV
                     MGLMTEMNVTEQTMQQNHANLE"
     gene            2224..2871
                     /locus_tag="RFE25_001644"
     CDS             2224..2871
                     /locus_tag="RFE25_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDU2816701.1"
                     /translation="MKFDNYIFDFDGTLADTKKCGEVATQSAFKACGLTEPSSKEITH
                     YMGIPIEESFLKLADRPLDEAALAKLIDTFRHTYQSIEKDYIYEFAGITEAITSLYNQ
                     GKKLFVVSSKKSDVLERNLSAIGLNHLITEAVGSDQVSAYKPNPEGIHTIVQRYNLNS
                     QQTVYIGDSTFDVEMAQHAGVPSAAVTWGAHDARSLLHSNPDFIINDPSEINTVL"
     gene            3373..4773
                     /locus_tag="RFE25_001645"
     CDS             3373..4773
                     /locus_tag="RFE25_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2816702.1"
                     /translation="MDFNKENINMVDAKKAKKTVVATGIGNAMEWFDFGVYAYTTAYI
                     GANFFSPVENADIRQMLTFAALAIAFLLRPIGGVVFGIIGDKYGRKVVLTSTIILMAF
                     STLTIGLLPSYDQIGLWAPILLLLARVLQGFSTGGEYAGAMTYVAESSPDKRRNSLGS
                     GLEIGTLSGYIAASIMIAVLTFFLTDEQMASFGWRIPFLLGLFLGLFGLYLRRKLEES
                     PVFENDVATQPERDNINFLQIIRFYYKDIFVCFVAVVFFNVTNYMVTAYLPTYLEQVI
                     KLDATTTSVLITCVMAIMIPLALMFGKLADKIGEKKVFLIGTGGLTLFSIIAFMLLHS
                     QSFVVIVIGIFILGFFLSTYEATMPGSLPTMFYSHIRYRTLSVTFNISVSIFGGTTPL
                     VATWLVTKTGDPLAPAYYLTAISVIGFLVITFLHLSTAGKSLKGSYPNVDNEQDRAYY
                     AEHPKEALWWVKERKN"
     gene            5317..6693
                     /locus_tag="RFE25_001646"
     CDS             5317..6693
                     /locus_tag="RFE25_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDU2816703.1"
                     /translation="MNVILEQLKTHTQNKPNDIALHIDDETITYSQLNARITSAVESL
                     QKYSLNPVVAINMKSPVQSIICYLALHRLHKVPMMMEGKWQSTIHRQLIEKYGIKDVI
                     GDTGLMQNIDSPMFIDSTQLQHYPNLLHIGFTSGTTGLPKAYYRDEDSWLASFEVNEM
                     LMLKNENAIAAPGPLSHSLTLYALLFALSSGRTFIGQTTFHPEKLLNQCHKISSYKVA
                     MFLVPTMIKSLLLVYNNEHTIQSFFSSGDKLHSSIFKKIKNQANDINLIEFFGTSETS
                     FISYNLNQQAPVESVGVLFPNVELKTTNHDHNGIGTICIKSNMMFSGYVSEQCINNDE
                     WFVTNDNGYVKEQYLYLTGRQQDMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNE
                     RFGQIGVLLYSGDVTLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKIAREKMM
                     SMYLRGEL"
     gene            6695..7834
                     /locus_tag="RFE25_001647"
     CDS             6695..7834
                     /locus_tag="RFE25_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDU2816704.1"
                     /translation="MNQAVIVAAKRTAFGKYGGTLKHLEPEQLLKPLFQHFKEKYPEV
                     ISKIDDVVLGNVVGNGGNIARKALLEAGLKDSIPGVTIDRQCGSGLESVQYACRMIQA
                     GAGKVYIAGGVESTSRAPWKIKRPHSVYETALPEFYERASFAPEMSDPSMIQGAENVA
                     KMYDVSRELQDEFAYRSHQLTAENVKNGNISQEILPITVKGEIFNTDESLKSHIPKDN
                     FGRFKPVIKGGTVTAANSCMKNDGAVLLLIMEKDMAYELGFEHGLLFKDGVTVGVDSN
                     FPGIGPVPAISNLLKRNQLTIENIEVIEINEAFSAQVVACQQALNISNTQLNIWGGAL
                     ASGHPYGASGAQLVTRLFYMFDKETMIASMGIGGGLGNAALFTRF"
     gene            7809..8174
                     /locus_tag="RFE25_001648"
     CDS             7809..8174
                     /locus_tag="RFE25_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein VraC"
                     /protein_id="HDU2816705.1"
                     /translation="MQHYLLDSNQRLNVSFSKDSVAAYYQCFNQPYRKEVPPLMCASL
                     WPKFDLFKKYANSELILTKSAINQTQKIEVDTIYVGHLEDIECRQTRNITRYTMALTL
                     TKNDQHVITVTQTFIKAMK"
     gene            8177..8446
                     /locus_tag="RFE25_001649"
     CDS             8177..8446
                     /locus_tag="RFE25_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816706.1"
                     /translation="MKFNEIWINEYLALVNDDNPIHNEIVPGQLVSQMMLMAMSLETN
                     QCQINYVKPILINENIEFIEQHEHEIIAINDDGEIKIKISLSTKK"
     gene            complement(8647..8814)
                     /locus_tag="RFE25_001650"
     CDS             complement(8647..8814)
                     /locus_tag="RFE25_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein VraX"
                     /protein_id="HDU2816707.1"
                     /translation="MIIYRQYHHEGAPVYEIITKTFQHVSIKCDDSFSDTEIFKLLSL
                     LQDDIDHMKVS"
     gene            complement(9321..10151)
                     /gene="thiD"
                     /locus_tag="RFE25_001651"
     CDS             complement(9321..10151)
                     /gene="thiD"
                     /locus_tag="RFE25_001651"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDU2816708.1"
                     /translation="MALKKVLTIAGSDTSAGAGMQADLKTFQELDTYGMVALTAIVTM
                     DKDTWSHDVTPLPMDVFEKQLETALSIGPDAIKTGMLGTEEIIKRAGEVYEASNAQYF
                     VVDPVMVCKGEDEVLNPGNTEAMIKYLLPKATVVTPNLFEAGQLSGLGKLNSIEDMKK
                     AATIIFDKGAQHVIIKGGKALDQDKSYDLYYDGQTFYQLTTDMFQQSYNHGAGCTFAA
                     ATTAYLANGKSPKEAVISAKAFVASAIKNGWKMNDFVGPVDHGAYNRIEHIDVEVTEV
                     "
     gene            10335..10991
                     /locus_tag="RFE25_001652"
     CDS             10335..10991
                     /locus_tag="RFE25_001652"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDU2816709.1"
                     /translation="MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFD
                     LTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTP
                     HLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
                     AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
                     "
     gene            10992..11372
                     /locus_tag="RFE25_001653"
     CDS             10992..11372
                     /locus_tag="RFE25_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5327 family protein"
                     /protein_id="HDU2816710.1"
                     /translation="MVNRETLIARIEQELVQAEQAQHDHDFEKHMYAIHILTSLYAST
                     SNTPHIGEQQMNRRIANHNQMPQSQITQPTHQVTAAEIEAMGGKVNTHSAHHHNKSYS
                     QPSNQQQRLATDDDIGNGESIFDF"
     gene            11505..11873
                     /locus_tag="RFE25_001654"
     CDS             11505..11873
                     /locus_tag="RFE25_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HDU2816711.1"
                     /translation="MKLFIILGALNAMMAVGTGAFGAHGLQGKISDHYLSVWEKATTY
                     QMYHGLALLIIGVISGTTSINVNWAGWLIFAGIIFFSGSLYILVLTQIKVLGAITPIG
                     GVLFIIGWIMLIIATFKFAG"
     gene            11994..13478
                     /locus_tag="RFE25_001655"
     CDS             11994..13478
                     /locus_tag="RFE25_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDU2816712.1"
                     /translation="MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFILPGDWIK
                     QSGPIAASIGIVIGALLMILIAVSYGALVERFPVSGGAFAFSFLSFGRYVSFFSSWFL
                     TFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
                     TIRGASVSGSLQYYFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVI
                     VSVAPWAYVGFDNIPQTAEEFNFAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQ
                     SLNGQLWLTGAVTQTSFGYIGLGVLAIAIMMGIFTGLNGFLMSSSRLLFSMGRSGIMP
                     TMFSKLHSKYKTPYVAIIFLVGVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAA
                     KLFSYNKQSNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIG
                     LIFFVIRYPKLKNMDNDELSRLILNRSENEVDDMIEEPEKEKTK"
     gene            complement(13619..14071)
                     /locus_tag="RFE25_001656"
     CDS             complement(13619..14071)
                     /locus_tag="RFE25_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDU2816713.1"
                     /translation="MFWILNFIFSFLASMFFCVIFDAPRKLYLSCGFVGTCGWMVYTL
                     FFNGFNVHTIYSSFFGSLALGLLSHYMARKQKEPAIIFMVTGIIPLVPGGLAYDATKN
                     LVLLNFSTAINTMLEVTLIAGAIALGLLFADQISKLIVSGFVKSFKRL"
     gene            complement(14084..14848)
                     /locus_tag="RFE25_001657"
     CDS             complement(14084..14848)
                     /locus_tag="RFE25_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDU2816714.1"
                     /translation="MDINSEEYKQEVLIKDVVMLAARILLESGAEGTRVEDTMTRIAK
                     KLGYSESNSFVTNTVIQFTLHSESFPRIFRITSRDTNLIKISQANKISRQITNNEISL
                     AEAKTQLEKIYVAKRDSSLPFKGFAAAMIAMSFLYLQGGRLIDVLTAILAGSLGYLVT
                     EILDRKLHAQFIPEFIGSLVIGIIAVIGHTLIPTGDLATIIIAAVMPIVPGVLITNAI
                     QDLFGGHMLMFTTKSLEALVTAFGIGAGVGSVLILV"
     gene            complement(15397..16149)
                     /locus_tag="RFE25_001658"
     CDS             complement(15397..16149)
                     /locus_tag="RFE25_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-dependent peroxidase"
                     /protein_id="HDU2816715.1"
                     /translation="MSQAAETLDGWYSLHLFYAVDWASLRIVPKDERDALVTEFQSFL
                     ENTATVRSSKSGDQAIYNITGQKADLLLWFLRPEMKSLNHIENEFNKLRIADFLIPTY
                     SYVSVIELSNYLAGKSDEDPYENPHIKARLYPELPHSDYICFYPMNKRRNETYNWYML
                     TMEERQKLMYDHGMIGRKYAGKIKQFITGSVGFDDFEWGVTLFSDDVLQFKKIVYEMR
                     FDETTARYGEFGSFFVGHLINTNEFDQFFAIS"
     gene            16317..17303
                     /gene="pta"
                     /locus_tag="RFE25_001659"
     CDS             16317..17303
                     /gene="pta"
                     /locus_tag="RFE25_001659"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDU2816716.1"
                     /translation="MADLLNVLKDKLSGKNVKIVLPEGEDERVLTAATQLQATDYVTP
                     IVLGDETKVQSLAQKLDLDISNIELINPATSELKAELVQSFVERRKGKATEEQAQELL
                     NNVNYFGTMLVYAGKADGLVSGAAHSTGDTVRPALQIIKTKPGVSRTSGIFFMIKGDE
                     QYIFGDCAINPELDSQGLAEIAVESAKSALSFGMDPKVAMLSFSTKGSAKSDDVTKVQ
                     EAVKLAQQKAEEEKLEAIIDGEFQFDAAIVPGVAEKKAPGAKLQGDANVFVFPSLEAG
                     NIGYKIAQRLGGYDAVGPVLQGLNSPVNDLSRGCSIEDVYNLSIITAAQALQ"
     gene            17306..18142
                     /locus_tag="RFE25_001660"
     CDS             17306..18142
                     /locus_tag="RFE25_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014532577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDU2816717.1"
                     /translation="MDLASKYFNGVNWRYIDHSSGLEPMQSFAFDDTFCESVGKDISD
                     NVVRTWIHQHTVILGIHDSRLPFLKDGIDYLTNEIGYNAIVRNSGGLGVVLDQGVLNI
                     SLMFKGQTETTIDEAFTVMYLLISKMFEDENVDIDTMEIEHSYCPGKFDLSIDGKKFA
                     GISQRRVRGGIAVQIYLCVEGSGSERALMMQTFYEHALKGEVTKFKYPEIEPSCMASL
                     ETLLNKTITVQDVMFLLLYAIKDLGGVLNMTPITQEEWQRYDTYFDKMIERNKKMIDQ
                     MQ"
     gene            18729..19649
                     /gene="mvk"
                     /locus_tag="RFE25_001661"
     CDS             18729..19649
                     /gene="mvk"
                     /locus_tag="RFE25_001661"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HDU2816718.1"
                     /translation="MTRKGYGESTGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEAL
                     ESGNYSSIKSDVYDGMLYDAPDHLKSLVNRFVELNNITEPLAVTIQTNLPPSRGLGSS
                     AAVAVAFVRASYDFLGKSLTKEELIEKANWAEQIAHGKPSGIDTQTIVSGKPVWFQKG
                     HAETLKTLSLDGYMVVIDTGVKGSTRQAVEDVHKLCEDPQYMSHVKHIGKLVLRASDV
                     IEHHNFEALADIFNECHADLKALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLL
                     LAKDLPTAKNIVKAVEKAGAAHTWIENLGG"
     gene            19654..20637
                     /gene="mvaD"
                     /locus_tag="RFE25_001662"
     CDS             19654..20637
                     /gene="mvaD"
                     /locus_tag="RFE25_001662"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HDU2816719.1"
                     /translation="MIKSGKARAHTNIALIKYWGKKDEALIIPMNNSISVTLEKFYTE
                     TKVTFNDQLTQDQFWLNGEKVSGKELEKISKYMDIVRNRAGIDWYAEIESDNFVPTAA
                     GLASSASAYAALAAACNQALDLQLSDKDLSRLARIGSGSASRSIYGGFAEWEKGYNDE
                     TSYAVPLESNHFEDDLAMIFVVINQHSKKVPSRYGMSLTRNTSRFYQYWLDHIDEDLA
                     EAKAAIQDKDFKRLGEVIEENGLRMHATNLGSTPPFTYLVQESYDVMALVHECREAGY
                     PCYFTMDAGPNVKILVEKKNKQQIIDKLLTQFDNNQIIDSDIIATGIEIIE"
     gene            20650..21726
                     /locus_tag="RFE25_001663"
     CDS             20650..21726
                     /locus_tag="RFE25_001663"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HDU2816720.1"
                     /translation="MIQVKAPGKLYIVGEYAVTEPGYKSVLIALDRFVTATIEEADQY
                     KGTIHSKALHHNPVTFSRDEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHF
                     HLTIDSNLDDSNGHKYGLGSSAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQS
                     LSSCGDIAVSVYSGWLAYSTFDHEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENME
                     VLIGWTGSPASSPHFVSEVKRLKSDPSFYGDFLEDSHRCVEKLIHAFKTNNIKGVQKM
                     VRQNRTIIQRMDKEATVDIETEKLKYLCDIAEKYHGASKTSGAGGGDCGITIINKDVD
                     KEKIYDEWTKHGIKPLKFNIYHGQ"
     gene            21903..22244
                     /locus_tag="RFE25_001664"
     CDS             21903..22244
                     /locus_tag="RFE25_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDU2816721.1"
                     /translation="MKNTFLICDECQAVNIRTLQKKLEKLDPDAEIVIGCQSYCGPGR
                     RKTFTFVNNRPLAALTEEELIEKVSQQLKKPRDPEEEERLRKRHEERKRRKEEQDRKL
                     KEKLEKRKAQQ"
     gene            complement(22296..23618)
                     /locus_tag="RFE25_001665"
     CDS             complement(22296..23618)
                     /locus_tag="RFE25_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HDU2816722.1"
                     /translation="MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCI
                     NIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFK
                     SNTEVNLLDQHGDIVDSITAPHIIINIGATSIIPNIKGLDQAKHVFDSTGLLNISYQP
                     KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIAL
                     HTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNTALALENTDIELGDRGEIK
                     VNAQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVF
                     IDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILG
                     ATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF"
     gene            complement(23605..24045)
                     /locus_tag="RFE25_001666"
     CDS             complement(23605..24045)
                     /locus_tag="RFE25_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006189740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDU2816723.1"
                     /translation="MNLEFNIAVHVLAFLTKHHSEKFNSSSLAELTCLNPVQLRRVTT
                     QLVDLKMIDTIRGKDGGYLANDQSADVSLATLYKHFVLEKEHHTRLFTGDEGSHCQIA
                     RNIATTMSHYQQDEQNIIINFYNEKTIKDVIEDIQKEDLCHENI"
     gene            24103..24204
                     /locus_tag="RFE25_001667"
     CDS             24103..24204
                     /locus_tag="RFE25_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816724.1"
                     /translation="MCQYLCLKSVELGVVIVMIYCLKVDALTVRLHN"
     gene            24670..26064
                     /locus_tag="RFE25_001668"
     CDS             24670..26064
                     /locus_tag="RFE25_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDU2816725.1"
                     /translation="MSIDMYLDRSRNQASSVGNLSQTMNSNYDALEKAITQFINDDAL
                     KGKAYTSAKQFFSTVLIPLSTSMKTLSDLTKQACDNFVSRYTSEVDSISLKESELEED
                     IRSLSQQITRYENLTNNLKKHASDNQQAISSNQQIIQTLGQQKHELEEKLRKLREFNQ
                     KSPEIFKEVEEFQKIVQQGLTQAQNFWNFSTNQFNIPSGKELDWAKASHEKYLKVAMG
                     KIEHKAEKETLNKADFAVIKAYAKEHPEDDIPKSIMKYINDNKDSIKRDIGLDITSTL
                     LEQGGINASKFGVFINTAGGVKGPAGPNSFVEVKRTSGNVFIENGSKFAKGGKYLGKG
                     VAGVGFGIGMYDDLANDNKTFGEALSHNGMTLAAGSVAAFGVAALVSNPVGWAVVGIL
                     TAGIIGSTVSDYLYQNNYFGIKDKVDWAGHKIDEGIDAVNKTAEKAVDSVGNAIGDAT
                     KSISNHINPMKWSW"
     gene            26065..>26549
                     /locus_tag="RFE25_001669"
     CDS             26065..>26549
                     /locus_tag="RFE25_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDU2816726.1"
                     /translation="MLLCESKVINKNPKYRIIKYESEYLMIDLASNWIVFFFPFINWL
                     IPKTYVKITKNDYEKLNIVKPVKNKSIGWTIFAGIVLLGGTVRRNTYLFDFQLEKLIV
                     WSSCFIGFLGVIFFYCYLNKKLTLNVYKENKNNELKLRLLPSFKNMCFTIFYYLFTGF
                     MS"
BASE COUNT         9249 a         3884 c         4946 g         8470 t
ORIGIN      
        1 agtgttaaac attaaaaatg atgctatatt aatggtgtat gaatgaattc ataagttttt
       61 aaaatgtatt aaatttgtgg aggcatgtaa acaatgaaag tattaaactt aggatcgaaa
      121 aaacaagcat cattctatgt tgcatgtgag ttatataaag agatggcatt taatcagcac
      181 tgtaaactag gtttagcaac tggtggtaca atgacagatt tgtatgaaca acttgttaag
      241 ttattaaata aaaatcagtt aaacgtagac aatgtatcca cgtttaattt agacgaatat
      301 gtaggtttaa ccgcatcaca tccgcaaagt tatcactatt atatggatga catgcttttc
      361 aaacaatatc cttattttaa tagaaagaac attcatattc caaatggaga tgccgatgat
      421 atgaatgcgg aagcgtcaaa atataatgac gttttagaac aacaaggtca acgtgatatt
      481 caaattttag gtattggtga aaatggtcat attggattta atgaacctgg tacgccgttt
      541 gatagcgtta ctcatatcgt tgatttgact gaaagtacta ttaaggctaa tagtcgatat
      601 tttaaaaacg aagatgatgt tccaaagcaa gccatttcga tgggacttgc taatattctt
      661 caagccaaac gtatcatttt actcgcattt ggtgaaaaga aacgtgctgc tattacacat
      721 ttattaaatc aggaaatttc tgttgatgtt ccagccacat tacttcacaa acacccgaat
      781 gttgagatat atttagacga cgaagcttgc ccgaaaaatg ttgcgaaaat tcatgtcgat
      841 gaaatggatt gattgcaatg tttaattaag aaatgcctcg ggaaaggttc caatagaaag
      901 ataaaaagca ttggaaggat gatttttagt ggaattacaa ttagcaattg atttattaaa
      961 caaagaagac gcggctgagt tagcaaataa agtaaaagat tatgtagata tcgtagaaat
     1021 cggtacgcca atcatttaca acgaaggttt accagcagtt aaacatatgg cagacaacat
     1081 tagtaatgta aaagtattag cagacatgaa aattatggat gcagctgatt atgaagttag
     1141 ccaagcaatt aaatttggcg cggatgtaat tacaatacta ggtgttgcag aagatgcatc
     1201 aattaaagca gctattgaag aagctcataa aaataataaa caattactag ttgatatgat
     1261 tgctgttcaa gatttagaaa aacgtgcaaa agaactagat gaaatgggtg ctgattatat
     1321 tgcagtacac actggttatg atttacaagc agaagggcaa tcaccattag aaagtttaag
     1381 aaccgttaaa tctgttatta aaaaatctaa agttgcagta gcaggtggaa ttaaaccaga
     1441 tacaattaaa gatattgtcg ctgaaagtcc tgatcttgtt attgttggtg gcggaatcgc
     1501 aaatgcagat gatccagtag aagctgcaaa acaatgtcgc gctgcaatcg aaggtaagta
     1561 atatggctaa atttagtgac tatcaattaa ttctagatga attaaagatg actttgtcac
     1621 atgttgaagc ggatgagttt tcaacttttg catccaaaat actacatgct gaacatatat
     1681 ttgtagctgg caaaggacgt tcaggattcg tggcgaatag ttttgcaatg cgcttaaatc
     1741 agctcggcaa acaggcacat gttgttggag aatcaacgac acctgcgatt aagtcgaatg
     1801 atgtatttgt aattatctct ggttcaggtt ccacggaaca tttaagatta ttagcagaca
     1861 aagcaaaatc agtaggtgct gacatcgtat taattactac aaataaagat tctgcaatag
     1921 gcaatctagc tgggacgaac atcgttttgc ctgcaggtac aaaatatgat gaacaaggct
     1981 cggcacaacc attaggaagt ttgtttgaac aagcatctca attattttta gatagtgttg
     2041 taatgggatt gatgactgaa atgaatgtta cggaacaaac gatgcaacaa aatcatgcta
     2101 atttagaata aaataaagat agtcgataat atgatgccta ggcagaaata ttatcgatta
     2161 tttttttatt taaataataa attatagtat aatatcaata ataaacgaat aggggtgtta
     2221 atattgaagt ttgacaatta tatttttgat tttgatggta cgttggcaga cacgaaaaaa
     2281 tgtggtgaag tagcaacaca aagtgcattt aaagcatgtg gcttaacgga accatcatct
     2341 aaagaaataa cgcattatat gggaatacct attgaagaat catttttaaa attagcagac
     2401 cgaccattag atgaagcagc attagcaaag ttaatcgata catttagaca tacatatcaa
     2461 tctattgaaa aggactatat ttatgaattt gcgggtataa ctgaagccat tacaagtttg
     2521 tataaccaag ggaaaaaact tttcgtggtg tctagtaaga agagtgatgt attagaaaga
     2581 aatttatcgg ctattggatt aaatcacttg attaccgaag ctgttggatc cgatcaagta
     2641 agtgcatata aaccaaatcc tgaaggcata cacacaattg tgcaacgcta caatttaaat
     2701 agccaacaaa cggtttatat tggtgattca acatttgatg ttgagatggc gcaacatgct
     2761 ggtgtaccat ctgcagcagt aacatgggga gcacatgatg caaggtcatt acttcattca
     2821 aatccagatt ttataatcaa tgatccatca gaaattaata cagtattata aaatttgtta
     2881 aaacagagaa taccatggtt aaaatgcata ttcataaata ttagattata catagaaata
     2941 tttcgcttta gattaggaat gtaaaataaa tatttattaa taatcgtgta tgtttaaaga
     3001 gtgatgtctg attcgttgat catttatttt tgtacaaata aattaaagta aaaacaaagt
     3061 tattgaagta aatcgaatat aaacatttta atatgatgag gaaagtagtg atagcatatg
     3121 acttacatga agttgtgtgc tatcgctatt tttagttata attccaaaaa gttaatcgtt
     3181 cgatgattta agaattatta ttgtttaatt caaatgtatg agggtataaa atcattgaat
     3241 ttaattcgat aaagtgaaat ttttgaacaa acatactttt gtatttatat aaaagtttaa
     3301 attcttataa atttgacaaa actaattaac tccgtataat tatgaaacat acaagaggga
     3361 gtgtatgaat tcatggattt taataaagag aatattaaca tggtggatgc aaagaaagct
     3421 aaaaaaaccg ttgttgcaac cggtatcggt aatgcaatgg aatggttcga ttttggtgtc
     3481 tatgcatata caactgcgta cattggagcg aacttcttct ctccagtaga gaatgcagac
     3541 attcgacaaa tgttgacttt cgcagcatta gccattgcgt ttttattaag accaattggt
     3601 ggtgtggtat ttggtattat tggtgacaaa tatggacgta aagttgtatt aacatctaca
     3661 attattttaa tggcattttc aacattaacc attggattat tgccaagcta tgatcaaatt
     3721 ggactttggg caccaatact attattgctt gcaagagtac tacaagggtt ttcaacaggt
     3781 ggagagtatg cgggggcaat gacatatgtt gcggagtcat ctccagataa gcgtcgtaac
     3841 tcattaggta gtggactaga aattgggaca ttatcaggtt acatagctgc ttcaattatg
     3901 attgcagtat taacattctt tttaacagat gaacaaatgg catcatttgg ttggagaatc
     3961 ccattcttac ttggtttatt cctaggatta ttcggcttat atttacgtcg taagcttgaa
     4021 gaatcaccag ttttcgaaaa tgatgttgca acacaaccag aacgagacaa cattaacttt
     4081 ttacaaatca tcagatttta ttacaaagat atatttgtgt gttttgtagc tgttgtattc
     4141 ttcaatgtta cgaactatat ggtaactgca tatttaccaa cctatttaga acaagttatt
     4201 aaattagatg caacgacaac aagtgtatta attacttgtg tcatggcaat aatgattcca
     4261 ttagcattaa tgtttggtaa gttagcggat aaaataggtg aaaagaaagt atttctaatt
     4321 ggtactggtg ggctaacatt atttagtatc atcgcattta tgttattaca ttcacaatca
     4381 tttgttgtaa tagtaatcgg tatatttata ttaggatttt tcttatcaac ttacgaagcg
     4441 acaatgccag ggtcgttacc aacgatgttt tacagtcata taagatatcg aactttatca
     4501 gtaacattta atatctctgt ttcgatattt ggtggtacga cgccattagt tgcaacatgg
     4561 ttagttacga aaactggaga tccattagca cctgcgtatt atttaacagc aatcagtgtt
     4621 attggctttt tagttattac attcttacat ttaagtacag caggaaaatc tctaaaaggt
     4681 tcgtatccaa atgtagataa cgagcaagat agagcttatt atgcagaaca cccaaaagaa
     4741 gcattatggt gggttaaaga acgtaagaat tagagatttt aataaaaagt ataaatcaat
     4801 cgtatataag cactttaaag ctagtaggtt ctgctaactt taaagtgctt tttaaattga
     4861 gaactgtaat tagccgtaat aaagtttttg tatatacata aacccccact gcaatgatta
     4921 tcgcaatggg ggaaagaggg gacttaaagc atatgtttag ctttgaatac ttaaaattct
     4981 cttgctattg aaatgttagg atgtaaatat gtcttagagt attttgtcca acgcaattaa
     5041 tattgagact ctaaccttca atattattat agagaacaca aacttaaata gattgggtga
     5101 cttatttgtg tcagttattg cgattgcgat aacttctttt ctctatatac atatagtaac
     5161 gtcttatcta ataaaaaaca tggtactaca gtatcaaatt tatctagggc ttaagtttga
     5221 tttttataat aggcaggttt acctgataaa aatacttatt cattatataa tgttaacaag
     5281 atgtatttta aagtttacat tgagtgaggg atattgatga acgtaatttt agaacagttg
     5341 aaaacacata ctcaaaataa acctaatgac atagcattac atatcgatga tgaaacaatt
     5401 acatatagtc aactaaatgc ccgcatcact agcgcagttg aatctttgca gaaatattca
     5461 cttaaccctg tcgttgctat taatatgaaa tcaccggtgc aaagtattat ttgttattta
     5521 gctttgcatc gtttacataa agtgcctatg atgatggaag gtaaatggca aagtactata
     5581 catcgtcaat tgattgaaaa atatggtatt aaagatgtaa ttggagatac aggtctcatg
     5641 cagaatatag actcaccgat gtttattgat tcaacgcaat tacagcacta ccccaattta
     5701 ttacatattg gttttacttc agggacaact ggactgccaa aagcatatta tcgtgatgaa
     5761 gattcatggt tggcttcttt tgaagttaat gaaatgttga tgttaaaaaa tgaaaatgca
     5821 atagcagccc ctggaccact atcgcactcg ttaacattat atgcgttatt gtttgcttta
     5881 agttccggtc gtacttttat aggacagacc acttttcatc ctgaaaagtt acttaatcaa
     5941 tgtcataaaa tatcatcata caaagttgct atgtttcttg ttccaacgat gattaaatca
     6001 ttattgttag tttacaacaa tgaacataca atccaatcat tttttagcag tggagataag
     6061 ctgcattctt ctatttttaa aaagataaaa aatcaagcaa atgacataaa tttgattgaa
     6121 ttttttggta catcggaaac cagttttatc agctataact tgaatcagca agcaccagtt
     6181 gaatcagtag gtgtgctatt tccaaatgtg gaattgaaaa caacgaatca cgatcacaat
     6241 ggtataggaa ctatttgtat aaaaagtaat atgatgttta gtggctatgt aagtgaacaa
     6301 tgtataaata atgatgaatg gtttgttact aatgataatg gctatgtaaa agagcagtat
     6361 ttatatttaa cgggacgtca acaggatatg ttaattattg gtggtcaaaa tatatatcca
     6421 gcacatgttg aacgcctttt aacgcaatct tcgagcattg atgaagcaat tatcatcggt
     6481 attccaaatg agcgttttgg tcaaataggc gtattgcttt attctggtga tgtgacactt
     6541 acacataaaa atgtaaaaca atttttaaaa aagaaagtga aacgctatga aattccatcg
     6601 atgattcatc atgtagaaaa gatgtattac actgcaagtg gtaaaattgc tagagaaaaa
     6661 atgatgtcga tgtatttgag aggtgaatta taatatgaat caagcagtca tagttgcagc
     6721 taaacgaact gcatttggga aatatggtgg cactttaaaa catttagagc cagaacaatt
     6781 gcttaaacct ttattccaac attttaaaga gaagtatcca gaggtaatat ctaaaataga
     6841 tgatgtagtt ttaggtaatg ttgttgggaa tggtggcaat attgcaagaa aagcattgct
     6901 tgaagcgggg cttaaagatt caatacctgg cgtcacaatc gatcggcaat gtgggtctgg
     6961 acttgaaagt gttcaatatg catgtcgcat gatccaagcc ggagctggca aggtatatat
     7021 tgcaggtggt gttgaaagta caagtcgagc accttggaaa atcaaacgac cgcattctgt
     7081 gtacgaaaca gcattacctg agttttatga gcgtgcatca tttgcacctg aaatgagcga
     7141 cccatcaatg attcaaggtg ctgaaaatgt ggccaagatg tatgatgttt caagagaatt
     7201 acaagatgaa tttgcttatc gaagtcatca actgacagcg gaaaatgtaa agaatggaaa
     7261 tatttctcag gaaatattac ctataaccgt taaaggagaa atattcaata ctgatgaaag
     7321 tctaaaatca catattccga aagataactt tggccgattt aagcccgtaa tcaaaggtgg
     7381 gaccgttacc gctgcgaata gttgtatgaa aaatgatggt gcagttttat tgcttattat
     7441 ggaaaaagat atggcatacg aattaggttt cgagcatggt ttattattta aagatggtgt
     7501 tacggtaggt gttgattcta attttcctgg cattggtcca gtaccagcca tttccaactt
     7561 actaaaaaga aatcaattaa cgatagaaaa tattgaagtc attgaaatta acgaagcgtt
     7621 cagtgcacag gtagttgcct gccaacaagc tttaaatatt tcaaatacgc aattaaatat
     7681 atggggtggt gcattagcat caggtcatcc atacggtgca agcggtgccc aattagtgac
     7741 tcgattattt tatatgtttg acaaagagac tatgattgca tctatgggga tagggggagg
     7801 tctaggaaat gcagcattat ttactcgatt ctaaccagcg attaaatgtg tcattttcta
     7861 aggatagtgt ggctgcatat tatcagtgtt ttaaccaacc ttatagaaaa gaagtaccac
     7921 cattaatgtg tgcgtcatta tggccaaaat ttgatttatt taaaaaatat gcaaatagcg
     7981 aactgatttt aacaaaatca gcaattaatc aaactcaaaa gatagaagta gacacaatat
     8041 atgtagggca tttagaagat attgaatgcc gacagactcg caatatcaca cgttatacaa
     8101 tggctttaac attaactaaa aatgatcaac atgtcataac ggttacacaa acttttatta
     8161 aggcgatgaa gtagagatga agtttaatga gatatggata aatgaatatt tggcgctcgt
     8221 aaatgatgat aatccaatac ataatgagat tgtgccagga caattagtga gtcaaatgat
     8281 gctgatggct atgtcattag agacaaacca gtgtcaaatt aactacgtta aacctatttt
     8341 aataaatgaa aatatcgaat tcattgaaca acacgaacac gaaattatag caattaatga
     8401 cgatggagag attaaaataa aaatttcttt gagcacaaaa aaataaccga tattagctgc
     8461 atgaacgcat attaattagg agatgaaagg acagctaata tcagttatgt attgttatta
     8521 ttattgggaa cagagatgaa tataggttac gtttctttct ttgcacgggg atgcattaat
     8581 ctaaaataat aataacaact atatcaatgt ttaataaatt ctggattatt ggaacgatta
     8641 gtcaatttaa ctaactttca tatgatctat atcgtcttgt aataaagaga gcaatttgaa
     8701 tatttcagta tcactaaatg aatcgtcaca tttaattgaa acatgctgaa acgttttggt
     8761 tataatttca taaactggtg cgccttcatg gtgatactgt cgataaataa tcataaccta
     8821 tattacctcc tttgctactc tatggttata ttataaataa catttttatg tgtgacatca
     8881 accttaagta tcaacttttt atcagacata gaacgtatga tttactaaga ctatttatgt
     8941 ataaaagttc taaataaata tatatttata gagtcgcctg gcagtcattt gggaaatata
     9001 acatatatga ttagagaggc atctatcgca aaagaatgat aatgatagag gtattgagca
     9061 tatagatgag tttaagttca tcttgaaaat aaagggttat ttagtcatag atgtagatgt
     9121 ataggaaata tttgtatgta ttgttcgata tgtatgaaat tttcaataaa agctaataac
     9181 gcttatatgt aactttcaaa tttaaattat atacagagca tgatgattat aaaaaaataa
     9241 ccacatcaca taaattgagt tcatacccaa tttaagtggt gtggctaata atgttgattt
     9301 atagatgaac cgcctaatcg ttaaacctct gttacttcaa catcgatatg ttcaatacgg
     9361 ttgtatgcac cgtgatccac aggaccaaca aaatcattca ttttccaacc gtttttaata
     9421 gcagaagcga cgaaagcttt cgcgctaatc acagcttctt tcggtgactt accgttagct
     9481 aaatatgcag ttgttgccgc agcaaatgta caaccagcac catggttata actttgttgg
     9541 aacatgtctg ttgttagttg ataaaatgtt tgaccatcat agtataagtc atacgattta
     9601 tcttgatcta aagctttgcc acctttaatg atgacatgct gtgcgccttt atcaaagata
     9661 attgttgcag cctttttcat atcttcaatt gaatttaatt tacctaatcc tgataattga
     9721 cccgcttcaa ataagtttgg tgtcactacc gttgctttag gtagtaaata tttaatcatc
     9781 gcctcagtat ttccaggatt aagcacttca tcttcgcctt tacaaaccat gacaggatct
     9841 actacaaaat attgtgcatt agatgcctca tatacttctc cagcacgttt gattatctcc
     9901 tcagtaccta acatacctgt tttaatagca tcaggtccga ttgataaagc cgtttcaagt
     9961 tgtttttcaa atacatccat tggtaatggt gtaacatcgt gtgaccatgt atctttatcc
    10021 atagtaacga tggcagttaa agcgaccatg ccatacgtat ctaattcttg gaacgttttc
    10081 aaatctgctt gcatacctgc gccagcactt gtgtcagaac cggcaattgt taaaactttc
    10141 tttaaagcca ttgagcttca ctcctacata ataatattgt attcatcata tcatttttaa
    10201 cctaattgaa aaatattaag cattcaatat ttgatgattg ttgaaatgaa tcattcatac
    10261 tattgtaact tttgaaaatg tcattcactt tagataagtg tgatatgtta aaatatgtcc
    10321 tgaggtgaga ttgaatggaa tggtcgcaaa tttttcatga cataacaacg aaacatgact
    10381 ttaaagctat gcatgatttt ttagaaaaag aatattcgac tgcaatcgta taccctgata
    10441 gggaaaatat atatcaagcg tttgatttaa caccgtttga aaatatcaaa gttgttatat
    10501 taggacaaga cccgtatcat ggtccaaacc aagcacatgg attagcattt tcagtgcaac
    10561 ctaacgcaaa attccctcca tctttacgta atatgtataa agaattagca gatgatattg
    10621 gatgcgttag acaaacaccg catttacaag attgggcaag agaaggcgtc ttgttattga
    10681 atacagtttt aaccgtaaga cagggtgaag caaattctca tcgtgatatt ggttgggaaa
    10741 catttactga tgaaattatt aaagcagtgt ctgattataa agaacatgtt gtctttattt
    10801 tgtgggggaa acctgcacag caaaaaataa agcttatcga tacatctaaa cattgtatta
    10861 taaaatcagt gcatcctagt ccactgtctg catatagagg attctttgga tcaaaaccgt
    10921 attccaaagc gaatgcctat ttagagtcag taggaaaatc accaattaat tggtgtgaaa
    10981 gtgaggcgta gatggtgaat agagaaactt taatagcacg aattgagcaa gaattagtac
    11041 aagcagagca ggcacagcat gaccatgact ttgaaaaaca tatgtatgcc atacatatat
    11101 taacatcttt atatgcttca acatcaaata caccacatat tggtgaacaa caaatgaatc
    11161 gtcgtattgc taaccataat caaatgccac aatcacaaat aacgcagcca actcatcaag
    11221 tgacagctgc tgaaattgaa gcgatgggtg gtaaagtaaa tacgcattca gcacatcatc
    11281 ataataagtc atattcacaa ccttcaaacc aacaacaaag attagcgaca gatgatgaca
    11341 ttggcaatgg tgaatccata tttgattttt aaaaagcaac aatgaaacat aattacttaa
    11401 tagcttgtta agtatgttgg ttaataatca agacgcatat acttttattc gagtgttcgg
    11461 atttaaacat ttattaatac tgaattatat aaggagaggt agcaatgaaa ttatttatta
    11521 ttttaggtgc attaaacgcg atgatggctg tcggaacagg tgcatttggt gcgcatggtt
    11581 tacaaggaaa aataagtgat cactatttat cagtatggga aaaagcaacg acgtatcaaa
    11641 tgtaccatgg cttagcatta ttaattatag gtgtaattag tggtacaact tcaatcaatg
    11701 ttaactgggc tggctggtta atatttgctg gtattatttt ctttagtgga tcattatata
    11761 ttttagtatt aactcaaatt aaagttttag gtgcgattac gccaattggt ggcgtattgt
    11821 tcatcattgg ctggataatg ttaatcattg cgacattcaa atttgctggt taaattttaa
    11881 aactttagat tacctatgta actaaacatt aaatttttaa taaaaataat caagaaaaag
    11941 agttacaaac tcatcttttg ggtatagaat accttcgagg tgagttttta tttatggaaa
    12001 aaaagaataa gcaaatagat agaggcgatt taaaacaaaa cctatctgaa aagtttgtat
    12061 gggcgattgc atatggttca tgtatcggat ggggcgcatt catcttacca ggagactgga
    12121 ttaagcagtc aggtccgatt gcagcatcaa ttggtatagt tattggtgca ttattaatga
    12181 tattaattgc ggttagttat ggcgcattag tagagagatt tccagtatca gggggcgcgt
    12241 ttgcctttag tttcttaagt ttcggcagat atgtgagttt cttctcatca tggtttttaa
    12301 cttttggtta tgtctgtgtc gttgctttaa atgcgaccgc attcagttta ctagttaaat
    12361 tcttattgcc agatgtctta aataatggga aactatacac cattgcgggc tgggacgttt
    12421 atattacgga aatcattatt gcgaccgtat tactacttgt attcatgcta gtaacgattc
    12481 gtggcgcaag tgtatctgga tcattacaat attatttctg tgtggcgatg gtaatcgtcg
    12541 tattattgat gttctttggt tcattctttg gtaataattt tgcacttgaa aatttacaac
    12601 cgttagctga acctagcaaa ggatggttag tgtctattgt ggttattgta tccgtggcac
    12661 catgggcata tgttggattt gataatattc cacaaacagc agaagagttt aactttgcac
    12721 caaacaagac atttaagctt atcgtgtaca gtttattagc agcatcatta acttatgttg
    12781 tcatgatttt atacactggt tggttatcaa caagtcatca aagtttaaat gggcagttgt
    12841 ggttaacagg tgctgttaca caaacatcat ttggttatat tggattaggt gtattagcaa
    12901 ttgcaattat gatgggtata tttactggtt taaatggatt cttgatgagt tcaagtcgct
    12961 tgttattttc tatgggacgt tcaggtatta tgccaacaat gtttagtaaa ttacatagta
    13021 aatacaaaac accatatgtc gcaatcatat tcctagtagg tgtgtcgtta attgcacctt
    13081 ggctaggaag aactgcattg acttggattg tagatatgtc atctacaggt gtatccattg
    13141 cctactttat tacatgtttg tctgcagcga aattattcag ttataacaaa caaagtaata
    13201 cgtatgcacc ggtttacaaa acgtttgcta ttatcggctc atttgtatca ttcattttct
    13261 tagcgttgtt attagtgcca ggttctcctg cagcactgac tgcaccatct tatattgcat
    13321 tgcttggatg gttaatcatc ggtttaatat tctttgtgat tcgatatcct aaattgaaaa
    13381 atatggataa tgatgaatta agtcgcttga ttttaaatag aagtgaaaat gaagttgatg
    13441 atatgattga agaacctgaa aaagaaaaaa ctaaataata aaagaatcgc acaatatacc
    13501 ttcttcattc ggaggcgtat cgtgcgattt tttgtattat aaattgacat ttaagacgag
    13561 gcagctgaac cttatatata attgctaaga gtttgggctg agccatttct aacaatattt
    13621 ataatcgttt aaaagatttc acgaacccag aaacaattaa tttggaaatt tggtcggcga
    13681 ataataaacc taatgcgatg gcgcctgcaa taagtgttac ttctaacatg gtattgattg
    13741 ctgtgctgaa atttaataag actaaatttt ttgtagcatc gtatgctaat ccacctggta
    13801 ctaatggaat gatacccgtt accataaaaa tgatggcagg ttctttttgt ttacgagcca
    13861 tataatgact taacaagcct aatgctaaac taccaaagaa actagagtat atagtgtgca
    13921 cattaaagcc gttgaagaat aaggtgtaaa ccatccatcc acatgtacca acgaaaccac
    13981 atgatagata taattttcta ggtgcatcaa aaatgacgca gaagaacatt gaagctaaaa
    14041 agctaaagat aaagtttaag atccaaaaca tagtctgata ctcctatact aaaattaata
    14101 cgctaccaac gccagcaccg atgccaaacg cagtaaccaa tgcttctaat gatttcgttg
    14161 tgaacatcaa catgtgtcca ccaaataaat cttgtattgc gtttgttatt aatacaccag
    14221 gaacaatagg catgactgcc gcaatgataa tagttgccaa gtcacctgtt gggataagtg
    14281 tatgtccaat aacggcgata atcccaataa ctaatgaacc aatgaattct gggataaact
    14341 gtgcatgtaa cttgcgatct aaaatctcag tgactaggta tcctagacta cctgctaata
    14401 tcgcagttaa aacatcaatc aatctaccac cttgtaaata taagaaactc attgcaatca
    14461 ttgctgcagc aaaaccttta aagggaagac tgctgtcacg cttagcaaca tatatttttt
    14521 caagttgtgt ttttgcttcg gctaaagaaa tttcattatt tgtaatttga cgcgaaattt
    14581 tattagcttg cgaaattttt attaagtttg tatctcgaga ggtaattcta aatattctag
    14641 gaaacgattc cgaatgtaac gtaaactgga tgacagtgtt tgtaacaaag ctgttacttt
    14701 cactgtaacc aagttttttt gcaatacgtg tcatggtatc ttctacacgc gtaccttctg
    14761 caccagattc taatagtatg cgagcagcaa gcatgacaac gtctttgata agtacctctt
    14821 gtttgtattc ttctgaattt atgtccattt catcaccatt gtttataaga atttaatact
    14881 cattatagtt tatacactat aaaataacca catgagcttt ttgataagtt gttattgatt
    14941 ttaaaaaact aatatttgat actattgtaa taataatcat tggaattttt agtagttaaa
    15001 attctcttga agtataaaaa gggaaaatta ttgaaaaaaa ttcgacaaaa atatgtttca
    15061 aatatttcaa ataggttaaa ataatattag ttaaccatta caaaaattgt atagagtagc
    15121 gactgtataa tttctattga ggttaacgtt tatatgtagt gatagtagtt aaagttctcc
    15181 caaggaagac tactcgggta cactttgcta tgagcaaagt gtactttgtt attgataata
    15241 cattagcaca tatatataag tttaaacata cagatttcaa ctatttacca aatcacgtct
    15301 tatgtatacg ggaatatact gaagataaac gaaaaattcc aagcttaaac cgataagctt
    15361 ggaatttttt tattaattta taaacgtacc aatgtattaa gaaatcgcaa agaattgatc
    15421 gaattcgttt gtgttaataa gatgtcctac aaagaaacta ccgaattcac cgtatcgtgc
    15481 tgttgtttca tcaaagcgca tttcgtatac aatttttttg aattgtaata cgtcatctga
    15541 gaacaatgtt acgccccatt cgaaatcatc aaaccctaca gaaccagtaa taaattgttt
    15601 gattttgcca gcatattttc taccaatcat accatggtca tacattaatt tttggcgttc
    15661 ttccatagtt aacatgtacc agttataagt ttcattacga cgtttgttca ttggatagaa
    15721 acaaatataa tcagaatgtg gtaattctgg gtataatctt gctttgatat gagggttctc
    15781 ataaggatct tcatcagatt taccagctaa ataattgctc aattcaatga ctgatacata
    15841 tgaatatgta gggattagga agtcagcaat gcgcaatttg ttaaattcat tttcaatatg
    15901 atttaaagac ttcatttcag gacgtaagaa ccataataac aaatctgctt tttgaccagt
    15961 tatattataa atagcttgat caccagattt tgatgatctt acagttgctg tattttctaa
    16021 aaatgattga aattcagtga caagtgcatc gcgttcgtcc tttggaacta tacgtaatga
    16081 tgcccaatca actgcataaa ataaatgtag actataccaa ccatctaatg tttcggctgc
    16141 ttgactcatg tttatcgctc cttttcaaaa atcatcagtt ctttataaat tttatcataa
    16201 agcaaagggg taacgataaa attatgatta caaattggtg acgtggcatt atgaaataaa
    16261 atggcgtata attataccgt gaatgattaa taagatttat attacaggag gacattatgg
    16321 ctgatttatt aaatgtatta aaagacaaac tttctggtaa aaacgttaaa atcgtattac
    16381 ctgaaggaga ggacgaacgt gttctaacag ctgcaacaca attacaagca acagattatg
    16441 ttacaccaat cgtgttaggt gatgagacta aggttcaatc tttagcgcaa aaacttgatc
    16501 ttgatatttc taatattgaa ttaattaatc ctgcgacaag tgaattgaaa gctgaattag
    16561 ttcaatcatt tgttgaacga cgtaaaggta aagcgactga agaacaagca caagaattat
    16621 taaacaatgt gaactacttc ggtacaatgc ttgtttatgc tggtaaagca gatggtttag
    16681 ttagtggtgc agcacattca acaggagaca ctgtgcgtcc agctttacaa atcatcaaaa
    16741 cgaaaccagg tgtatcaaga acatcaggta tcttctttat gattaaaggt gatgaacaat
    16801 acatctttgg tgattgtgca atcaatccag aacttgattc acaaggactt gcagaaattg
    16861 cagtagaaag tgcaaaatca gcattaagct ttggcatgga tccaaaagtt gcaatgttaa
    16921 gcttttcaac aaaagggtct gctaaatcag acgacgtgac aaaagttcaa gaagctgtca
    16981 aattagcaca acaaaaagct gaagaagaaa aattagaagc aatcattgat ggcgaattcc
    17041 aatttgatgc tgcgattgta ccaggtgttg ctgagaaaaa agcgccaggt gctaaattac
    17101 aaggtgatgc aaatgtcttt gtattcccaa gtttagaagc tggtaatatt ggttacaaaa
    17161 ttgcacaacg tttaggtgga tatgatgcag ttggtccagt attacaaggt ttaaattctc
    17221 cagtaaatga cttatcacgt ggctgctcaa ttgaagatgt atacaatctt tcaattatta
    17281 cagcagcgca agccttacaa taacgatgga tttagcgagt aaatatttta atggcgtcaa
    17341 ctggcgatat atcgaccatt cttctggatt agaacctatg caatctttcg cattcgatga
    17401 tacattttgc gaaagtgtgg gcaaagatat atcagataat gttgtgcgta cttggattca
    17461 tcaacatact gttattcttg gtattcatga ttcaagattg ccgtttttaa aagatggcat
    17521 tgattattta acgaatgaga ttggttataa tgccattgtt agaaattctg gtggcttagg
    17581 tgtcgttcta gatcaaggtg tattaaatat atcgctgatg ttcaaaggac aaacagaaac
    17641 aacgattgat gaagcgttta ctgtgatgta cctcttaatt agcaaaatgt tcgaagatga
    17701 gaatgttgat attgatacga tggaaattga acattcttat tgcccaggaa aatttgactt
    17761 aagtatcgat ggtaagaaat ttgcaggcat atcgcaacga agagttagag gcggtattgc
    17821 tgtacaaatt tatctttgtg ttgaaggctc tggttcagaa cgtgcattga tgatgcaaac
    17881 attttatgaa catgctttaa aaggtgaagt gactaaattt aaatatcctg aaattgaacc
    17941 atcttgtatg gcctcattag agacattgct taacaaaacg attactgttc aagatgtaat
    18001 gtttttacta ttatatgcaa tcaaagatct tggcggtgta ttaaatatga cgcccattac
    18061 tcaagaagaa tggcaaagat acgatacgta ttttgataaa atgattgaaa gaaacaagaa
    18121 aatgatagac caaatgcaat agttaaatat ttaacagccc ctttcaagtt atcgtttggg
    18181 gctgttattt ttgaaagtat ccataaaaag cataaatatg ttattgacct aatatttaaa
    18241 ttgaacatca ttaaattaaa agtaatgata tgatggaaat aataaattta ataagaaaat
    18301 ttcatgtttt acgtattaaa tagattgaga atagggtata tataatgcgt atgactatga
    18361 aagaaacgac cttctattga aatgttctaa tactttagta gtaaatctat atattccaat
    18421 tattatttgt agtattatag ttagggtgga aaattataaa ttgtagggct attttataaa
    18481 aagataaaga atctgaaata tcactcgata agatttaaac tttgaagtaa acgaaagtta
    18541 gttttatact aatcaagtta agtcaaatat aaattcaaaa taaagattat acataatatg
    18601 aataatgtga gataaagact gcaatgaaat ttaacgcgaa tgcgtatgca acttagaata
    18661 tgatgtcttt tactaataaa taaaaataat gaatcaagta taggataaat ataaaaggtg
    18721 atattgacat gacaagaaaa ggatatgggg aatcgacagg taagattatt ttaataggag
    18781 aacatgctgt tacatttgga gagcctgcta ttgcagtacc gtttaacgca ggtaaaatca
    18841 aagttttaat agaagcctta gagagcggga actattcgtc tattaaaagc gatgtttacg
    18901 atggtatgtt atatgatgcg cctgaccatc ttaagtcttt ggtgaaccgt tttgtagaat
    18961 taaataatat tacagagccg ctagcagtaa cgatccaaac gaatttacca ccatcacgtg
    19021 gattaggatc gagtgcagct gtcgcggttg cttttgttcg tgcaagttat gattttttag
    19081 ggaaatcatt aacgaaagaa gaactcattg aaaaggctaa ttgggcagag caaattgcac
    19141 atggtaaacc aagtggtatt gatacgcaaa cgattgtatc aggcaaacca gtttggttcc
    19201 aaaaaggtca tgctgaaaca ttgaaaacgt taagtttaga cggctatatg gttgttattg
    19261 atactggtgt gaaaggttca acaagacaag cggtagaaga tgttcataaa ctttgtgagg
    19321 atcctcagta catgtcacat gtaaaacata tcggtaagtt agttttacgt gcgagtgatg
    19381 tgattgaaca tcataacttt gaagccctag cggatatttt taatgaatgt catgcggatt
    19441 taaaggcgtt gacagttagt catgataaaa tagaacaatt aatgaaaatt ggtaaagaaa
    19501 atggtgcgat tgctggaaaa cttactggtg ctggtcgtgg tggaagtatg ttattgcttg
    19561 ccaaagattt accaacagcg aaaaatattg tgaaagctgt agaaaaagct ggtgcagcac
    19621 atacatggat tgagaattta ggaggttaat gcgttgatta aaagtggcaa agcacgtgca
    19681 catacgaata ttgcacttat aaaatattgg ggtaaaaaag atgaagcact aatcattcca
    19741 atgaataata gcatatctgt tacattagaa aaattttaca ctgaaacgaa agtcactttt
    19801 aacgaccagt taacacagga tcaattttgg ttgaatggtg aaaaggttag tggcaaagaa
    19861 ttagagaaaa tttcaaaata tatggatatt gtcagaaata gagctggcat cgattggtat
    19921 gctgaaattg aaagcgacaa ttttgtacca acagcagcag ggttggcttc atcagcaagc
    19981 gcatatgcag ctttagcagc agcttgtaat caagcactag acttgcagct gtcagataag
    20041 gatttatcga gattggcgcg aattggttcg ggttctgcgt cgcgtagtat ttatggtgga
    20101 tttgcagaat gggaaaaagg gtataatgat gagacgtcat atgccgttcc acttgaatcg
    20161 aatcattttg aagatgacct tgccatgata tttgttgtga ttaatcaaca ttctaaaaag
    20221 gtacctagtc gatatggtat gtcgttgaca cgaaacacat caaggtttta tcaatattgg
    20281 ttagatcata ttgatgaaga tttagctgaa gcaaaagcag cgattcaaga caaagatttt
    20341 aaacgccttg gtgaagtaat tgaagaaaat ggtttacgta tgcatgccac gaatctggga
    20401 tcaacaccgc cgttcactta tcttgtgcaa gaaagttatg atgtcatggc gctcgttcac
    20461 gaatgccgag aagcgggata tccgtgttat tttacgatgg atgcgggtcc taatgtgaaa
    20521 atacttgtag aaaagaaaaa caagcaacag attatagata aattattaac acagtttgat
    20581 aataaccaaa ttattgatag tgacattatt gccacaggaa ttgaaataat tgagtaagga
    20641 agagataaaa tgattcaggt caaagcaccc ggaaaacttt atattgttgg agaatatgct
    20701 gtaacagaac caggatataa atctgtactt attgcgttag atcgttttgt aactgctact
    20761 attgaagaag cagaccaata taaaggtacc attcattcaa aagcattaca tcataaccca
    20821 gttacattta gtagagatga agatagtatt gtcatttcag atccacatgc agcaaaacaa
    20881 ttaaattatg tggtcacagc tattgaaata tttgaacaat acgcgaaaag ttgcgatata
    20941 gcgatgaagc attttcatct gactattgat agtaatttag atgattcaaa tggtcataaa
    21001 tatggattag gttcaagtgc agcagtactt gtgtcagtta taaaagtatt aaatgaattt
    21061 tatgatatga agttatctaa tttatacatt tataaactag cagtgattgc aaatatgaag
    21121 ttacaaagtt taagttcatg cggagatatt gctgtgagtg tatatagtgg atggttagcg
    21181 tatagtactt ttgatcatga atgggttaag catcaaattg aagatactac ggttgaagaa
    21241 gttttaatca aaaactggcc tggattgcac atcgaaccat tacaagcacc tgaaaatatg
    21301 gaagtactta tcggttggac tggctcaccg gcgtcatcac cacactttgt tagcgaagtg
    21361 aaacgtttga aatcagatcc ttcattttac ggtgacttct tagaagattc acatcgttgt
    21421 gttgaaaagc ttattcatgc ttttaaaaca aataacatta aaggtgtgca aaagatggtg
    21481 cgtcagaatc gtacaattat tcaacgtatg gataaagaag ctacagttga tatagaaact
    21541 gaaaagctaa aatatttgtg tgatattgct gaaaagtatc acggtgcatc taaaacatca
    21601 ggcgctggtg gtggagactg tggtattaca attatcaata aagatgtaga taaagaaaaa
    21661 atttatgatg aatggacaaa acatggtatt aaaccattaa aatttaatat ttatcatggg
    21721 caataaatga tttgataggg gagcaatcat ctaatttaat tagaagataa atgctccatt
    21781 ttttattgcc agccgtgtta cgtatcttga aaaaaatatt aaaaagagta aaatagatag
    21841 agttaacgaa aaaattaatg aaatcgacga tatagatatg ataaagaaag gtgggtagca
    21901 atatgaaaaa tacattcctt atttgtgatg aatgtcaggc agtcaatata agaacgttac
    21961 aaaagaagtt ggaaaaatta gatcccgatg ctgaaatcgt gataggttgt caatcttatt
    22021 gtggacctgg acgccgaaaa acattcactt ttgttaataa ccgcccactg gctgcgctta
    22081 ctgaagaaga attaatcgaa aaagtttctc aacaattaaa gaaaccacgt gatcctgaag
    22141 aagaagagcg tttaagaaaa cgacatgaag aacgtaaacg tcgtaaagaa gaacaagata
    22201 gaaagcttaa agaaaaatta gaaaagcgaa aagcacaaca ataaaacctg atggcagcat
    22261 cattcaatgc gtgccaccag gtttttatgt tttgtctaga aattaaataa atcattaaat
    22321 gattcggcca tcgtaggatg tgtataaata ttatctcgta atacggtata tggaatgttt
    22381 tgatcaatcg caagtttaat tatattaatt aattcttcag attgcttacc atataatgta
    22441 gcacctaaaa tcatattatt ttcattatta atgactactt taaataaacc tcttggatca
    22501 ttgttaattt tgtgacgagg tatagcactt actaaaagtt gatgttcagt gtaatcataa
    22561 tgttgagcgg cagcttcttt actagttaat ccaacacgtg ataatggtgg atctataaat
    22621 actgtataag gcacgctacc tctattgtca gtcgtacgtg actgattacc atataacgct
    22681 gatttgataa ttcgataatc atctaaagat atatacgtaa attgaagtcc gcctttaaca
    22741 tcacctgcag cataaatatg tggcacagat gtttgaagtt gagcattgac tttaatttcg
    22801 cctctatcac ctaattcgat atcagtattt tctaaagcta aggctgtatt cggtttgcgc
    22861 ccgatagcca aaagtactgc atcagcctca aagttgccaa cattagtacg gactgttgta
    22921 tgatgatcgt cagatgacaa ttcagtcgtt tcaacatttg tatgcaatgc aatgccttta
    22981 ttttctaagt cagtaatagc atgtgcaacg acatcttgat cttcgcgtgg cataaatgat
    23041 tcaccacgtt ctaatactgt taccttacta cctaaattcg caaacattga agcaaattct
    23101 aaggcaatat aaccgccacc tacaataacg agatgcttag gttgatagct aatgtttaat
    23161 aaacctgttg aatcgaagac atgtttagct tgatcaaggc cttttatgtt aggaatgata
    23221 gaggtagcac cgatattaat aatgatatga ggtgcagtaa tactatcgac gatatcgcca
    23281 tgctgatcta ataaattcac ttcagtatta gatttaaact gcgctttaaa atccaataca
    23341 tcaatgttgt tatcgtctgc taataagtgg taatttttat tgtttagcgc attgacaaca
    23401 tcgtttttac ggttataact tgcttcaaaa gatttgcctt ctaatccatc atgtacaagt
    23461 gtcttcgaag gtatacatcc tatatttata caagtgccgc catacatttt cgaagattgt
    23521 tcgataactg cgacgtgttg acctgttgat gcagcatatt tcgctaaagt tttaccagct
    23581 ttcccaaatc ctattacaat taaatcatat gttttcatga cataaatcct ccttttgaat
    23641 gtcttcaatg acatctttga ttgttttttc attataaaaa ttaataatga tattctgttc
    23701 gtcttgctga taatgtgaca tggtagttgc aatattacga gcaatttgac agtgactgcc
    23761 ttcgtcgcca gtaaatagac gtgtgtggtg ttctttctct aagacaaaat gtttatataa
    23821 tgttgctaga gagacatcag cactttgatc atttgctaaa taaccgccat ctttacctcg
    23881 tattgtgtca atcattttta aatcgacaag ttgagtcgtc acgcgtcgta attgaacagg
    23941 atttaaacaa gttaattctg ctaatgaact actattgaat ttttctgaat gatgcttagt
    24001 taaaaaagct aatacatgca cggcaatgtt aaattctaaa ttcaatgttt ctcacctcat
    24061 aattgtaact gtattagtta caattaaaaa tcattttgct caatgtgtca atacttatgt
    24121 ttgaaaagtg ttgaattagg tgtggttatt gtgatgattt attgtttgaa agttgatgca
    24181 ttaacggtga gattgcacaa ttgaaatttt aattatgtat gaactgatag atatgaaatg
    24241 aatattgaaa atgagagcaa taaaattttg aatgatgatg ttgtgtgatt gtataaactt
    24301 attcgtattt tagatacgtt ttgatatttc gcatgatgag gaaatacttt taacaactga
    24361 tgacatattt taatagtgaa tatattttga gatattaata tatttaatgt taaggatgtt
    24421 gtcgcaataa aattaaaata ttgaaagata atttttattg attaattgcg aatatacaaa
    24481 gacaccatta tatccatatg ctaaaataag aaaaaaggcg acatgttatc tcaatttacc
    24541 tgcatctaga ctcctttaca taagaaataa tcatcgccga gttttaaaat tttacaactt
    24601 tgtagatgta aaaagcattt gattttaaat agtttgaaaa tcatatattt ttgaaaaagg
    24661 agcatgccga tgagtattga catgtattta gacagatctc gaaaccaagc ttcaagtgtg
    24721 gggaatttga gtcaaacaat gaattcaaat tatgatgcgt tggaaaaagc aattactcaa
    24781 tttatcaatg atgatgcgct taaagggaaa gcgtatacgt cagctaagca attttttagt
    24841 acggtgttaa ttccattatc aacaagtatg aaaacattga gtgatttaac gaagcaagct
    24901 tgcgataatt ttgtgtcacg ttatacgagt gaggttgata gcatatcttt aaaagaatca
    24961 gagcttgaag aagatatcag atcattaagt caacaaatta cgcgatatga aaatttaact
    25021 aacaatttga aaaagcatgc ttccgataat cagcaagcca tttcatcgaa ccaacaaata
    25081 atacaaacat taggtcaaca aaaacatgaa ttagaagaga aactacgtaa attacgtgag
    25141 tttaatcaaa aatcaccaga aatatttaaa gaagttgaag aatttcaaaa aattgtccaa
    25201 caaggactta cccaagcgca gaatttttgg aacttttcaa caaatcaatt taatatacct
    25261 tcaggtaaag aacttgattg ggctaaagca agtcatgaaa aatatttgaa agttgctatg
    25321 gggaaaattg aacataaagc agagaaagaa actttaaata aagcagactt tgctgttata
    25381 aaggcatatg ccaaagaaca tccagaagac gatatcccga aaagtataat gaaatatata
    25441 aatgacaata aagatagtat taaacgagat ataggattag atattacgtc aacactttta
    25501 gagcaaggcg gtataaatgc aagtaaattc ggtgtattta tcaatacagc aggtggagtg
    25561 aaaggcccag ccggtccaaa ttcatttgtg gaagtcaaac gtacatcagg taatgtgttt
    25621 atagaaaatg gtagtaaatt tgcaaaaggc ggaaaatatc tagggaaagg tgttgcaggt
    25681 gtaggatttg gtataggtat gtatgatgat cttgcaaatg ataataaaac atttggagag
    25741 gcattgtcgc ataatggtat gacgcttgca gctggatctg ttgcagcatt tggtgtagcg
    25801 gctttagtaa gtaatccagt cggttgggct gtggtaggta ttttaacagc aggtattatt
    25861 ggatctactg tttctgatta tctttatcaa aataattatt ttggcataaa agataaagtg
    25921 gactgggcag gacataaaat agacgagggt attgatgctg taaacaaaac tgcagaaaaa
    25981 gctgtagata gtgttggtaa tgccattggt gatgccacaa aaagtattag taatcatatt
    26041 aatcctatga aatggagttg gtaaatattg ctttgcgaat ctaaagttat taataaaaat
    26101 cctaaatatc gaataatcaa atacgaaagt gaatacttaa tgattgattt agcaagtaat
    26161 tggattgttt tcttctttcc atttattaac tggctcatac cgaaaacata tgtcaaaatc
    26221 actaagaatg attatgaaaa attaaatatt gtcaaaccag ttaaaaataa atcgatagga
    26281 tggactatat tcgcgggtat tgtgttactt ggtggtactg taagaagaaa tacttattta
    26341 tttgattttc aattagaaaa actaattgtt tggagcagct gttttattgg ttttttaggg
    26401 gttatatttt tttattgtta tctaaataag aaattaacat taaatgttta taaggaaaat
    26461 aaaaataatg aacttaaatt aagattatta ccctccttta aaaatatgtg tttcacaatt
    26521 ttttattacc tctttactgg tttcatgtc
//
LOCUS       DAPDIM010000038        26512 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000038 DAPDIM010000000
VERSION     DAPDIM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 26512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26512
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.038"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(69..1196)
                     /locus_tag="RFE25_001670"
     CDS             complement(69..1196)
                     /locus_tag="RFE25_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDU2816727.1"
                     /translation="MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVE
                     LPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKAL
                     VQIHHGGAQALPELIPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEAT
                     RRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYG
                     NKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAG
                     QERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIK
                     DGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK"
     gene            complement(1558..1935)
                     /locus_tag="RFE25_001671"
     CDS             complement(1558..1935)
                     /locus_tag="RFE25_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDU2816728.1"
                     /translation="MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYV
                     HNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKY
                     GFQTLKERLPIWIKQSKRAIRND"
     gene            complement(2350..2943)
                     /locus_tag="RFE25_001672"
     CDS             complement(2350..2943)
                     /locus_tag="RFE25_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDU2816729.1"
                     /translation="MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFV
                     THAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALS
                     MANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVF
                     GQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE"
     gene            3007..3390
                     /locus_tag="RFE25_001673"
     CDS             3007..3390
                     /locus_tag="RFE25_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase-associated lipoprotein B"
                     /protein_id="HDU2816730.1"
                     /translation="MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNP
                     TETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTK
                     HAEMSLASLARLKEDYSLQYKENFK"
     gene            3521..5926
                     /gene="mnhA1"
                     /locus_tag="RFE25_001674"
     CDS             3521..5926
                     /gene="mnhA1"
                     /locus_tag="RFE25_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit A"
                     /protein_id="HDU2816731.1"
                     /translation="MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIY
                     MLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYL
                     SKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIY
                     GAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIG
                     AFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTV
                     TLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYA
                     AAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITAL
                     SMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFI
                     MHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVLGLFPGILTNSIIEPATSSIN
                     HTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNR
                     SANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIF
                     EVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESIS
                     TALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFY
                     QEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVK
                     NHE"
     gene            5919..6347
                     /gene="mnhB1"
                     /locus_tag="RFE25_001675"
     CDS             5919..6347
                     /gene="mnhB1"
                     /locus_tag="RFE25_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit B"
                     /protein_id="HDU2816732.1"
                     /translation="MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGL
                     LFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFD
                     IPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE"
     gene            6347..6688
                     /gene="mnhC1"
                     /locus_tag="RFE25_001676"
     CDS             6347..6688
                     /gene="mnhC1"
                     /locus_tag="RFE25_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit C"
                     /protein_id="HDU2816733.1"
                     /translation="MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLI
                     TMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDN
                     VESMKGVPEDD"
     gene            6681..8177
                     /gene="mnhD1"
                     /locus_tag="RFE25_001677"
     CDS             6681..8177
                     /gene="mnhD1"
                     /locus_tag="RFE25_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit D"
                     /protein_id="HDU2816734.1"
                     /translation="MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLV
                     AAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTI
                     GIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQE
                     TIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIF
                     VFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSH
                     YVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYT
                     LHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSG
                     FYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVK
                     YLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK"
     gene            8179..8658
                     /gene="mnhE1"
                     /locus_tag="RFE25_001678"
     CDS             8179..8658
                     /gene="mnhE1"
                     /locus_tag="RFE25_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit E"
                     /protein_id="HDU2816735.1"
                     /translation="MAVQLVLNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRV
                     LPGRFYVITLYRIIKLVIIFLIELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQ
                     IVLLSNLITLTPGTVVLGVSDDRTKIYIHAIDFSTKEQEVESIKTSLEKIVREVGEI"
     gene            8658..8951
                     /gene="mnhF1"
                     /locus_tag="RFE25_001679"
     CDS             8658..8951
                     /gene="mnhF1"
                     /locus_tag="RFE25_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit F"
                     /protein_id="HDU2816736.1"
                     /translation="MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQ
                     LMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD"
     gene            8929..9285
                     /gene="mnhG1"
                     /locus_tag="RFE25_001680"
     CDS             8929..9285
                     /gene="mnhG1"
                     /locus_tag="RFE25_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit G"
                     /protein_id="HDU2816737.1"
                     /translation="MIKIILISLALIFVIIGALISALAAIGLLRLEDVYSRAHAAGKA
                     STLGAMSLLFGTFLYFIATQGFVNMQLIVAIIFVLITGPLSSHMIMKAAYNIKTPYTK
                     KTKVDEISEDLKDTKL"
     gene            9534..10688
                     /locus_tag="RFE25_001681"
     CDS             9534..10688
                     /locus_tag="RFE25_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDU2816738.1"
                     /translation="MHWTIIGGGIQGTAIAQKLLSSGLTTDLLTIIDPHETFCQRFNS
                     YTNRIEMPYLRSPIVHHVHPQPFHLKQFAKQHQYTNAFYGPYQRPELTMFMNHIAHAS
                     KQYQLEDCLVQGLVQTLDKQEDKWHIKLEDGQIITTDCVVIAIGSTNIPFMPDILKDK
                     QNVNHIFEKEHDQVVYDKTDHIVGSGITAAHLALKLLNHDNDKKIHLWLNKDIEIHDF
                     DADPGWLGPKNMSSFLSTKSMPERNAIVQRERHKGSMPHELYLRLKKHIKNGRINVHK
                     TPITQISGGVINTENDSVPYQQIMVATGFEQDFMSQPLIKQLIQNYDAPINECNYPVI
                     SEKLEWIPNLFVAGCFADLELGPFGRNVMGGRKAAERIEQAFLKLQQYSA"
     gene            complement(10744..11118)
                     /locus_tag="RFE25_001682"
     CDS             complement(10744..11118)
                     /locus_tag="RFE25_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDU2816739.1"
                     /translation="MTHLLETFEMSIDHQEDGLVVISMPVTDKVKQPFGYLHGGASIA
                     LGETACSLGSANLIDTTKFIPLGLEMNANHIHSAKDGRVTATAEIIHRGKSTHVWDIK
                     IKNDKEQLITVMRGTVAIKPLK"
     gene            complement(11137..12453)
                     /locus_tag="RFE25_001683"
     CDS             complement(11137..12453)
                     /locus_tag="RFE25_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter family protein"
                     /protein_id="HDU2816740.1"
                     /translation="MINAVVIAVILMIVLCLCRLNVVISLFISALVGGLISGMSIEKV
                     INVFGKNIVDGAEVALSYALLGGFAALISYSGITDYLVGKIINAIHAENSRWSRVKVK
                     VTIIIALLAMSIMSQNLIPVHIAFIPIVIPPLLSLFNDLKIDRRLIGLIIGFGLCFPY
                     VLLPYGFGQIFQQIIQSGFAKANHPIEFNMIWKAMLIPSMGYIVGLLIGLYVYRKPRE
                     YETRKISDSDNVTELKPYILIVTIVAILATFLVQTFTDSMIFGALAGVLVFFISRAYN
                     WYELDAKFVEGIKIMAYIGVVILTANGFAGVMNATGDIDELVKTLTSITGDNKLFSII
                     MMYVIGLIVTLGIGSSFATIPIIASLFIPFGASIGLDTMALIALIGTASALGDSGSPA
                     SDSTLGPTAGLNVDGQHDHIRDTCVPNFLFYNIPLMIFGTIAAMVL"
     gene            complement(12864..14339)
                     /locus_tag="RFE25_001684"
     CDS             complement(12864..14339)
                     /locus_tag="RFE25_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M17 family metallopeptidase"
                     /protein_id="HDU2816741.1"
                     /translation="MNFKLNNTLSNEINTLIIGIPEHLNQLERISFNHIDITESLERL
                     KHQHIIGSKVGKIYTTAFDVQDQTYRLITVGLGNLKARSYQDMLKIWGHLFQYIKSEH
                     IEDTYLLMDSFISKYDQLSDVLMACGIQSERATYEFDHYKSSKKAPFKTNLNLISESL
                     IELDFIHEGISIGQSINLARDFSNMPPNVLTPQTFAEDIVNHFKNTKVKVDVKDYDTL
                     VSEGFGLLQAVGKGSKHKPRLVTITYNGKDKDVAPIALVGKGITYDSGGYSIKTKNGM
                     ATMKFDMCGAANVVGIIEAASRLQLPVNIVGVLACAENMINEASMKPDDVFTALSGET
                     VEVMNTDAEGRLVLADAVYYANQYQPSVIMDFATLTGAAIVALGDDKAAAFESNSKVI
                     LNDILQISSKVDEMVFELPITATERASINHSDIADLVNHTNGQGKALFAASFVTHFSG
                     QTPHIHFDIAGPATTNKASYNGPKGPTGFMIPTIVQWLKQQ"
     gene            complement(14470..15678)
                     /locus_tag="RFE25_001685"
     CDS             complement(14470..15678)
                     /locus_tag="RFE25_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDU2816742.1"
                     /translation="MAQDRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYH
                     YEATWLHEASAGTLNYEDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQGIYDF
                     DILVVALGFVSETFGIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEKDDNDLS
                     ILVGGAGFTGVEFLGELTDRIPELCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHA
                     VSYLEDRGVEFKIATPIVACNEKGFVVEVDGEKQQLNAGTSVWAAGVRGSKLMEESFE
                     GVKRGRIVTKQDLTINGYDNIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIK
                     RILNGESTEEFEYVDRGTVCSLGSHDGVGMVFGKPIAGKKAAFMKKVIDTRAVFKIGG
                     IGLAFKKGKF"
     gene            complement(16132..16491)
                     /locus_tag="RFE25_001686"
     CDS             complement(16132..16491)
                     /locus_tag="RFE25_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly accessory protein"
                     /protein_id="HDU2816743.1"
                     /translation="MPTVILTEAAAYEVKDMLKANEMPDGYLKIKVNGGGCTGLTYGM
                     GAEEAPGENDEVLEYFGLKVLVDKEDAPVLNGTTIDFKQSLMGGGFQIDNPNAIASCG
                     CGSSFRTAKVAGNPENC"
     gene            complement(16504..16740)
                     /locus_tag="RFE25_001687"
     CDS             complement(16504..16740)
                     /locus_tag="RFE25_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YuzB family protein"
                     /protein_id="HDU2816744.1"
                     /translation="MNPIVEFCLSNMAKGGDYVFNQLENDPDVDVLEYGCLTHCGICS
                     AGLYALVNGDIVEGDSPEELLQNIYAHIKETWIF"
     gene            17057..18121
                     /locus_tag="RFE25_001688"
     CDS             17057..18121
                     /locus_tag="RFE25_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDU2816745.1"
                     /translation="MKNLVLLGGGYGNMRIMSRILTTSLPQDYTVTLVDRMPFHGLKP
                     EFYALAAGTKSDKDVRMKFPNHPQVNTVYGEINDIDLDAQIVSVGNSKIDYDELIIGL
                     GCEDKYHNVPGAEEYTHSIQTLSKARDTFHSISELPEGAKVGIVGAGLSGIELASELR
                     ESRSDLEIYLYDRGPRILRNFPEKLSKYVAKWFAKNNVTVVPNSNINKVEPGKIYNCD
                     EPKDIDLVVWTAGIQPVEVVRNLPIDINSNGRVIVNQYHQVPTYRNVYVVGDCADLPH
                     APSAQLAEVQGDQIADVLKKQWLNEPLPDKMPELKVQGIVGSLGDKQGFAYIMDRTVT
                     GRLASILKSGVLWLYKYHNG"
     gene            complement(18180..18503)
                     /locus_tag="RFE25_001689"
     CDS             complement(18180..18503)
                     /locus_tag="RFE25_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YuzD family protein"
                     /protein_id="HDU2816746.1"
                     /translation="MEHVSVVVYGADVICASCVNAPTSKDIYDWLQPLLKRKYPNISF
                     KYTYIDITKDNDNLTDHDLQFIERIEQDELFYPLITMNDEYVADGYIQTKQITRFIDQ
                     KLVNE"
     gene            18604..18846
                     /locus_tag="RFE25_001690"
     CDS             18604..18846
                     /locus_tag="RFE25_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDU2816747.1"
                     /translation="MPTEDTTMFDQVAEVIERLRPFLLRDGGDCSLIDVEDGIVKLQL
                     HGACGTCPSSTITLKAGIERALHEEVPGVIEVEQVF"
     gene            complement(19109..20284)
                     /gene="dltD"
                     /locus_tag="RFE25_001691"
     CDS             complement(19109..20284)
                     /gene="dltD"
                     /locus_tag="RFE25_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDU2816748.1"
                     /translation="MKLKPFLPILISGAVFIVFLLLPASWFTGLVNEKTVEDNRTSLT
                     DQVLKGTLIQDKLYESNKYYPIYGSSELGKDDPFNPAIALNKHNANKKAFLLGAGGST
                     DLINAVELASQYDKLKGKKLTFIISPQWFTNHGLTNQNFDARMSQTQINQMFQQKNMS
                     TELKRRYAQRLLQFPHVHNKEYLKSYAKNPKETKDSYISGFKENQLIKIEAIKSLFAM
                     DKSPLEHVKPATKPDASWDEMKQKAVEIGKADTTSNKFGIRDQYWKLIQESKRKVRRD
                     YEFNVNSPEFQDLELLVKTMRAAGADVQYVSIPSNGVWYDHIGIDKERRQAVYKKIHS
                     TVVDNGGKIYDMTDKDYEKYVISDAVHIGWKGWVYMDEQIAKHMKGEPQPEVDKPKN"
     gene            complement(20281..20517)
                     /gene="dltC"
                     /locus_tag="RFE25_001692"
     CDS             complement(20281..20517)
                     /gene="dltC"
                     /locus_tag="RFE25_001692"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002433359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     2"
                     /protein_id="HDU2816749.1"
                     /translation="MEFREQVLNLLAEVAENDIVKENPDVEIFEEGIIDSFQTVGLLL
                     EIQNKLDIEVSIMDFDRDEWATPNKIVEALEELR"
     gene            complement(20535..21749)
                     /gene="dltB"
                     /locus_tag="RFE25_001693"
     CDS             complement(20535..21749)
                     /gene="dltB"
                     /locus_tag="RFE25_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PG:teichoic acid D-alanyltransferase DltB"
                     /protein_id="HDU2816750.1"
                     /translation="MIPYGDFTFFLIALIALLPVIILGFLGKRSYIYNGVVTAFMIVL
                     IFSSDKHNLFDQKYLSVQLISFIIYVVWQVLLIMFYYHSKPKNNSFSKFVTVMVLSIL
                     PLALVKVLQSTWLGGHQIHFHESKLIEFVGFLGISYVTFKSVQLIMEIRDGSIKEIKV
                     WKLIQFISFFPTISSGPIDRYKRFVKDDKKVPTGNEYRELVLKAIHMIMLGFLYKYIV
                     AYFINTYAIMPLQLDLHGFVNLWLYMYAYSLYLFFDFAGYSLFAIAFSYLFGIKTPPN
                     FDKPFKAKNIKDFWNRWHMTLSFWFRDCIYMRSLFYMSRKKLLKSQFAMSNVAFLINF
                     FIMGIWHGIEVYYIVYGLYHAALFIGYGYYERWRKKHPPRWQNGFTTALSIVITFHFV
                     TFGFLIFSGKLI"
     gene            complement(21746..23203)
                     /gene="dltA"
                     /locus_tag="RFE25_001694"
     CDS             complement(21746..23203)
                     /gene="dltA"
                     /locus_tag="RFE25_001694"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HDU2816751.1"
                     /translation="MTDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRL
                     QGSKKPMILFGHMSPYMIVGMIGAIKAGCGYVPVDTSIPEDRIKMIINKVQAEFVFNT
                     TDESFESLEGEVFTIEDIKTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYAS
                     LVQFTEWMLELNKSGNKQQWLNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKL
                     LNEMLTATPINIWVSTPSFMEMCLLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVSR
                     FPSATIYNTYGPTEATVAVTSIQITQEILDQYPTLPVGVERLGARLSTTDDGELVIEG
                     QSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKFENGQWFIQGRIDFQIKLNGYRME
                     LEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKNIKNDLKSR
                     LPEYMIPRKFEWMEQLPLTSNGKIDRKKIAEVING"
     gene            complement(23219..23371)
                     /locus_tag="RFE25_001695"
     CDS             complement(23219..23371)
                     /locus_tag="RFE25_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HDU2816752.1"
                     /translation="MKSKSKQPPNKYVEAFKPYLLTLLYLAIFITLYLIYGSGDTHNN
                     FIYNEF"
     gene            complement(23419..23529)
                     /locus_tag="RFE25_001696"
     CDS             complement(23419..23529)
                     /locus_tag="RFE25_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816753.1"
                     /translation="MMTTNYYVESIKLKLNFIMNIDIMNCKKQILKRILY"
     gene            complement(23783..24742)
                     /locus_tag="RFE25_001697"
     CDS             complement(23783..24742)
                     /locus_tag="RFE25_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycerate dehydrogenase"
                     /protein_id="HDU2816754.1"
                     /translation="MVKIVVSRKIPDKFYQQLSKLGDVVMWQKSLVPMPKDQFVTALR
                     DADACFITLSEQIDAEILAQSPNLKVIANMAVGYDNIDVESATANNVVVTNTPNVLTE
                     TTAELGFTLMLAIARRIVEAEKYVEADAWQSWGPYLLSGKDVFNSTIGIYGMGDIGKA
                     FARRLQGFNTNILYHNRSRHKDAEADFNATYVSFETLLAESDFIICTAPLTKETHHKF
                     NAEAFEQMKNDAIFINIGRGQIVDETALIDALDNKEILACGLDVLANEPIDHTHPLMG
                     RDNVLITPHIGSASVTTRDNMIQLCINNIEAVMTNQVPHTPVN"
     gene            complement(24775..25554)
                     /locus_tag="RFE25_001698"
     CDS             complement(24775..25554)
                     /locus_tag="RFE25_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HDU2816755.1"
                     /translation="MKQYKAYLIDLDGTMYMGTDEIDGAKQFIDYLNVKGIPHLYVTN
                     NSTKTPEQVTEKLREMHIDAKPEEVVTSALATADYISEQSPGASVYMLGGSGLNTALT
                     EAGLVIKNDEHVDYVVIGLDEQVTYEKLAIATLGVRNGATFISTNPDVSIPKERGLLP
                     GNGAITSVVSVSTGVSPQFIGKPEPIIMVKALEILGLDKSEVAMVGDLYDTDIMSGIN
                     VGMDTIHVQTGVSTLEDVQNKNVPPTYSFKDLNEAIAELEK"
     gene            complement(25554..25988)
                     /locus_tag="RFE25_001699"
     CDS             complement(25554..25988)
                     /locus_tag="RFE25_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF86 domain-containing protein"
                     /protein_id="HDU2816756.1"
                     /translation="MYFVDKDKLTQKLAYLQALTDDYHESKHNHYAFERIAQMLIESS
                     VDIGNMIIDAFILRDPGNYKDVIDILELENVITKETQQEINKTVDIRKQFTYDYTALD
                     IKVIMPMFDDALPYYKQFITEVTIFLHQENVPVTAFGKGENQ"
     gene            26086..26352
                     /locus_tag="RFE25_001700"
     CDS             26086..26352
                     /locus_tag="RFE25_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3055 domain-containing protein"
                     /protein_id="HDU2816757.1"
                     /translation="MIDMYLYDDNEESQVQFVGFVGEHSRYDLMLVHTNRHYGKTLVL
                     NMQTNKFGIIGTDDLKEEGYIAHILGVNAEEGDEITEYLNEVIH"
BASE COUNT         8434 a         4656 c         3990 g         9432 t
ORIGIN      
        1 tatttataaa tattgaaaac cactaacaaa ttgcatacac aatatcatta gtggtaacag
       61 ttaaacactt atttatcttt acgtggtaat ggatagaatc cttcattaaa ttgatgccat
      121 aaattaggag ttaagtgatg attatcttct ctctctggat caaagtaatt aataatttca
      181 tcttcccgtc catctttaat tttttcaaca aattgataat ccagtagtag ctctctacca
      241 atggctacta agtcaacacc aacattttca actgcatcta aagcttcgtc agctgtgaaa
      301 attgaaccaa taccgataag tggcatacga ccatttatcc atttgtgaat taaaggtagt
      361 ctttcttgtc cagcgtattt accttcacgt gtcgttgcat gcgtatccat cattgaaaca
      421 tgaatatagt cgattggcat atggctaatt ttattaacga gttcctctgt aatttccatt
      481 gtgattcctg gagactccgc ttcctctgga gataatctgt atccaactat aaagtcttta
      541 ttgccatacg cttctttcgc tttaagcact tcttcaatca cagcgaccgg gaatttatat
      601 tgatttgccc atacatcatt tcttctatta tagtatggtg atacaaattg atgaattaag
      661 taatgattcg cgccatgtat ttcaacacca tcaaaccctg cttcaattgc acgtcgtgtt
      721 gcttcaccaa aatccttgat tgcttgttca atctcttcat tcgtcatttc tctagcacta
      781 tgttcttgtt tctgaccgaa actttttaaa gaaattggac ttggtgctac gacgtctcca
      841 tcaggtatta attcaggcaa tgcttgtgca ccaccatgat gtatttgtac gagtgctttg
      901 gcaccgtttt tcttcattgc tgtagctaat cgttttagtc cttcaatatc actgtcatgc
      961 gcgattgacg gctgtcctgg aaatgctttt ccgacatcac tcacattact cgcagcatta
     1021 attgtaatac caacatcttg tgaacgcttt tcaatataag gaagttctac atctgaaata
     1081 gtaccatcat catttgaaga aatatgtgtt aaaggggcta acacaaatcg atttctcaac
     1141 tctactccat ttggtaattc tactttatca aacaatggtt cgtatttact tttcattact
     1201 taattcctcc ttaaaattat tgagttgact ataacatgta attttttcat tctccaatta
     1261 tctgtttata tagttgcaat tcgtttaata ctttaagttg tagttctcat ttctaaaata
     1321 aataaaaaaa acaaatccac atacaatatt gcaaatcaac gattctatct aacaaagata
     1381 atggatatgt caccttaaac catttgtacg tgtaaataga atcaatcata ttacgttatc
     1441 gtagacaaaa agagattagt atctaataaa atttaataga tactaatctc ttttatagtc
     1501 taagaaactt tcatttcaga ccctttgtat gattttcggt acgatttatc tgttccttta
     1561 gtcgtttcga attgctcgct ttgactgttt tatccagatt ggtaagcgtt ctttaagtgt
     1621 ttgaaaccca tatttttctg tttctctgat ttcatctaat actgattgtt tttccttctt
     1681 acgctcataa tttttgaagt aatcattatc ctttaatgat agattaagct ttccttcatc
     1741 atctatagac aaaattttag ctttaacaat ttggccttct gatagaaatt tcttcaaatt
     1801 atgaacgtag tcatccataa tttctgatat atgaatcagt ccttcagtat gattaggggt
     1861 ctcaacaaac gcaccgtatg gttgaatacc agttacacgc accttgatat gttggccaat
     1921 tttgtagtta ttcaacttaa taacccctta tttcgtttac ttaacactat tatcatagca
     1981 caaatcgaaa tggtggacta attaaaacat caaatcatac gaatattatt ttataaatga
     2041 ataagaattc tacaaacttg gatttacaaa taaaattagc aacaaactcc tatctaaatc
     2101 aatatgatat ccagctactt tgttttcaat ttattaacta tttgaatagc aattctcttt
     2161 aaaaacataa aaagcaacct caactattat ctttagaata cacatctatt taaaaactgt
     2221 gctttcttga taaatatatt gagattgctc atcatgttag tttatttgtt tcgttggaat
     2281 atatactaat ccattcataa attagcttta tccgagttta aaatgttggt agttaattat
     2341 gtttagctat tattcttcaa catcaataga ttcaattaca acatcatgaa gtggtttgtc
     2401 ttgtggtccc acttttgtat ttgcaatatc ttctaaagta gtttcaccat caatgatttg
     2461 accgaatact gtatgttttt gatctaacca tggtgtacca cccttttcgc catatgcatc
     2521 aacgattggt tgaggccagc caccatctgc aagttgactt aacatatttt gaggtacttc
     2581 tttcatttga acaatgaaaa attgtgaacc attagtatta ggtcctgagt tagccattga
     2641 taatgcgcca tataagttaa atgcatttaa tgaaaattca tcttcaaaag caccgccata
     2701 aatactttcg ccacccatac cagtagctgt tggatcgcca ccttgaatca tgaagtcatt
     2761 aatgacacgg tggaatgtta ttccatcata ataaccattt tttgcatgtg tcacaaaatt
     2821 ttcaactgtt tttggtgcaa tatttggaaa taatttgaat gtcatgtcac ctttatttgt
     2881 gtgcataacc actttaattt caccttgttg tacttctttg tttaactgtg gatagttagc
     2941 catttatatt ctccattcat gttatgatac atatatatta acatactttt aagggaggaa
     3001 aatagcatga agctatatcg attttcacac aaaacaggta gctatggtgt cacgattgtt
     3061 gaagaaaatg gagacgatgt ccttgttaaa gttgaacaag ttatcaaaca cccgaaacaa
     3121 ggtgatttac ataaccctac tgaaactgaa ggtgtatttt tccatgaacg caaagcatta
     3181 agccattttg aaaaacgcta tacgaaacgt tcacaattac gcgacttcaa tgttgatgta
     3241 ttgcgctatg aagattcact tcaacaagca attacagatt tagaaactaa acttaaagct
     3301 cagcaaacaa aacatgctga aatgtcttta gctagtttag cacgcttaaa agaagattat
     3361 tcacttcaat acaaagaaaa ttttaaataa aaaatgacgt gtttcttctt atttaaatac
     3421 ttctgaaaat aaagcacaac aaggagtgtg tacgtttttc agaactatat cattcatgta
     3481 taatgaataa cataaatatt ttttaaagga ggacaacata gtgagtttgt tacatattgc
     3541 ggtgatatta ccgttaatat tcgcactcat tattcctatc ctgtatagat tttttaaacg
     3601 tatacattta ggatggttcg tattacctgt ccctatcgtc atatttattt atatgcttac
     3661 attaattaaa acgacgatgt caggtaatac tgtaatgaaa accttaaatt ggatgcctca
     3721 ttttggtatg aactttgatt tatatcttga tggcttaggt ttactcttta gtttgcttat
     3781 ttcaggaatc ggcagtttag tagtattata ttcaatcggc tacttaagta agtcagaaca
     3841 actagggaat ttttattgtt atttattact atttatgggt gcaatgttag gtgtcgtact
     3901 ttcagataat gttattattc tatatttatt ctgggagcta acgtcatttt ctagtttttt
     3961 acttatttca ttctggcgcg aacgacaagc atctatatat ggtgctcaaa aatcgctcat
     4021 aatcacagta tttggtggtc tatcattatt aggtggtatc atcttactcg ctataccaac
     4081 acaatcattt agcattcagt acatgattca acatgcttct gaaattcaaa atagcccatt
     4141 cttcattttt gcgatgattt taatcatgat tggtgctttt acaaaatctg ctcagtttcc
     4201 attttatatt tggctaccag atgcaatgga agcacctaca ccagtcagtg cttatcttca
     4261 ttcagcaaca atggttaaag cagggttata tttaatcgct cgaatgacac caatcttcgc
     4321 agcatcgcaa ggttgggtat ggactgtcac actcgttggt ttaattacgt tattctgggc
     4381 ttcgctaaac gcaacaaaac aacaagactt gaaaggtata ctggcatttt caacagtatc
     4441 ccaattaggt atgattatgg cgatgcttgg aatcggtgcc attagttatc actatcaagg
     4501 cgatgatagc aaaatatatg ctgctgcatt tacggctgca atattccatt taatcaacca
     4561 tgcaacattt aaaggtgccc tatttatgat tacaggtgca gtggatcatt ctactggtac
     4621 acgtgatgtt aagaaattag gtggcttact aacaattatg cctatttcat ttacaatcac
     4681 tgttattaca gcattaagta tggctggtgt accaccgttc aatggtttct tatcaaaaga
     4741 atcattttta gaaacaacat ttacagcaag ccaagcaaat ttattcagtg ttgatacatt
     4801 aggctaccta ttcccaatca ttggtatagt gggcagtgtc ttcacatttg tatattcaat
     4861 taaatttata atgcatatat ttttcggaca atataaacct gaacaattac ctaaaaaagc
     4921 acacgaagta tcaatattaa tgcttttatc accagctatt ttagctacat tagtaattgt
     4981 attgggttta ttccctggca ttttaactaa ttcgattatt gaaccagcta catcttcgat
     5041 taatcatacg gtaattgatg atgttgaatt ccatatgttc catggattaa cgcctgcctt
     5101 tttatcaaca ttagtgattt atattttagg tatcttacta attgtgacat ttagttattg
     5161 ggtgaaattg ttgcaacgac aacctggtaa actaacattc aattattggt acaacagaag
     5221 tgcaaatgtt attccaaact actctgaaaa gatgacgaat agctatgtta ccgattattc
     5281 acgtaataat ttagttatca tttttggtgc attaatttta ttaacatttg tcactatatt
     5341 ctcagtgcct ttcaacatta attttaaaga cgttagtccg attagaattt tcgaagtttg
     5401 tatcgtaatt ttattattaa gtgctgcctt tttaattctt ttcgctaaat caagattatt
     5461 tagcattatt atgttaagtg cagttggata tgctgtgtct gtattgttta tattctttaa
     5521 agcacccgac ttagcattga cacagtttgt cgttgaatct atttcaacag cattgttctt
     5581 attatgcttc taccacttac caaatttaaa tcgttataat gaaaagcgct cattccagct
     5641 tactaatgct ttaattgctg gtggtgttgg tttgtccgtc attattatcg gtttaattgc
     5701 atacggaaat agacattttg aatcgatatc taagttttat caagagcacg tttatgattt
     5761 agctcacggt aaaaacatgg taaacgtcat acttgttgat ttccgtggta tggatacttt
     5821 attcgagtca tctgtgcttg gtatcgcagg attagctgta tatacaatga ttaaattacg
     5881 taaaaagcgt caaacgcaag gtaacgaggt gaaaaatcat gaatagacaa caaaatgatc
     5941 taattttgca atttgctgca gttattatct ttttcatggt aatggtcttt ggtttttcac
     6001 ttttcttagc aggacattat acacctggtg gcggtttcgt cggcggatta ttattcgcaa
     6061 gttcacttgt tatcattacg attgcatttg atatagaaac aatgcgtaaa attttcccat
     6121 tagattttaa aatcttgata ggtatcggat tagttttttg tattgcgacg cctatcgcaa
     6181 gttggttttt aggcaaaaat ttctttacgc atgtcacatt tgatataccg ttatttatat
     6241 tagaacctgt tcatatgaca acagcagtat tctttgattt cggtgtttta tgtgcagtag
     6301 ttggtactgt catgacaatt attatttcga ttggagagaa cgaatagtgg aaattattat
     6361 gatttttgtt agtggtattc tcacagcaat tagtgtctat ctcgttttgt ctaaaagtct
     6421 gatacgaatt gttatgggaa ctacactatt aacacatgca gcaaacttat ttttaataac
     6481 tatgggcgga cttaaacatg gtactgttcc aatttatgaa gcgaacgtaa aaagctatgt
     6541 tgatcctatc ccgcaagcac ttattttaac agcaatcgtt atcgcctttg cgacaacagc
     6601 ctttttctta gtattagcat ttagaacata taaagaatta ggcacagata acgttgagag
     6661 tatgaaagga gttccagaag atgattgaaa gtaatatgct tgtgttaacg ctagttattc
     6721 cagtaattac agccatatta cttgtcttta ttggaaagcg tcctattata aagcgttatg
     6781 tcgcactagg cggtacatta ttaaccttgg tcgcggcaat tatcaattta gcaaatgttg
     6841 ttaaacatgg accaatacgc gtagagctag gttcatggaa agcaccatac agtattgtct
     6901 ttgtattaga catattcagt gccctactaa taattactag tattattatt acagctattg
     6961 tgattttata ttcataccaa acaattggta ttgaacgtga aagatattat tattattttt
     7021 cagtactatt tatgttaata ggtatcattg gtgcattcac aactggtgac attttcaacc
     7081 tattcgtatt tttcgaagta tttttaatgt catcttattt cttattagta attggttcta
     7141 caaaaattca actacaagaa acaatcaaat atgttcttgt taacgttgta tcgtcatcct
     7201 tcttcgtaat gggtgtagcg attttatatt cagtagtagg aacattgaat ctagcagata
     7261 taagcaataa attagctaac ctttcagcgc atgacagtgg cttagtcaat atcgttttca
     7321 tactatttat ctttgttttt gctacaaaag ctggcgtatt cccaatgttt gtttggttac
     7381 ctagtgcata ctatgcacca ccaattccaa tcattgcatt ctttggtgct ttgttaacaa
     7441 aagttggtgt ttatgcaatc gctagaacat taagcctatt ctttagtgat aatgtaagct
     7501 tttcacatta tgtcatttta ttcttagcac tattaacgat catctttggt tgtgtcggtg
     7561 ctgttgcata tgccaacatt aaaaaaatca tcctatacaa tgtcatgatt gctgtaggtg
     7621 tgatcttagt cggcgttgca atgatgacag agtcaggtat gattggggct atttactata
     7681 cattgcacga catgttagta aaacttgcat tattcttgct tatcggaatt atgattaaaa
     7741 ttacaggcac tgctgattta agacaatttg gtggcttaat taaacgatat cctgtacttg
     7801 gttggtcatt ctttatcgca gcattaagtt tagctggcat tcccccactc agtggctttt
     7861 atggaaaatt tttcattgtc caatcaacat ttgaaagagg attttattta agtggtgtca
     7921 tcgtcttatt atcaagttta gtcgtattat attctgtcat tcgcatattc ctacaaggct
     7981 ttttcggtca accaaaagga tatgatctta ataacaaagt cgacgtcaaa tatttaacta
     8041 cgattgcaat cgttgcagtt gtgataactg ttttatatgg attgtcagca gattacttat
     8101 atccaatggt aaaagctggt gcagaaacat tctacaatcc atcaacctac gttaaagctg
     8161 tattaggagg taaataacat ggctgtacaa ttagtattaa actttattat cgcagtgttt
     8221 tggttgtttg taacaaatag ttacacaaca aataactttg tgttaggttt catctttggc
     8281 ctagttcttg tttacctctt acacagagtg ttaccaggta gattttatgt catcacgcta
     8341 tatcgtatta ttaaattagt tattattttc ttaatcgaac tgattaaagc taattttgat
     8401 gttttgaaaa ttattattaa accttcgatt aaaaatgaac caggattctt tgtttatcac
     8461 acagatttaa aaaaagattg gcaaattgtc ttgctgtcta atttaattac attaacacct
     8521 ggtactgtag tgcttggtgt aagtgatgat cgtacaaaaa tttatattca tgccatagat
     8581 ttttcaacta aagagcaaga agtagaaagt attaaaacat cattagagaa aattgtaaga
     8641 gaggtgggcg aaatataatg aatcataatg ttattatcgt tattgcatta atcatagttg
     8701 tcatttctat gttagctatg ctcattcgcg ttgtgctagg cccatcactt gccgatcgtg
     8761 ttgtcgcatt agatgcgatt ggtcttcaat taatggcagt tatagcatta ttcagtattt
     8821 tattaaatat taaatacatg attgtcgtta ttatgatgat tggtatatta gcctttttag
     8881 gtactgcagt attctctaaa tttatggaca aaggtaaggt gattgaacat gatcaaaatc
     8941 atactgatta gtcttgcact tatctttgtt atcatcggtg ctttaattag cgccctagca
     9001 gctataggat tattgagact tgaagatgta tattcacgtg cacatgctgc cggaaaagca
     9061 tcaacattag gtgcaatgtc attactattt ggtacttttt tatattttat tgctactcaa
     9121 ggttttgtaa atatgcaatt aatcgttgcg attatctttg tattaattac aggtcctctt
     9181 tcaagtcata tgattatgaa agcagcatat aatattaaaa cgccttatac taaaaagact
     9241 aaagtcgatg aaatttcgga agacttaaaa gacacaaaat tgtagattat ataacaaaat
     9301 catgaatata aatcaacaac aaacagcagt aagatgattc caaattagga atgattttac
     9361 tgctgttttc ttttgacatt gttacctctt tttcaatgat tttttctttg actacatctt
     9421 cgccctatct acgtatatct ctttaattta attgcctttc atgtcgttat gtattatgat
     9481 aataataatc ataaatcgta acgattacgc tttaaaaaaa gagaggtttt attatgcatt
     9541 ggacaattat cggcggtggc atacagggaa ctgcaatcgc acaaaaacta ttatcaagcg
     9601 gattaacaac agacctatta acaatcattg acccacacga aactttttgc caaaggttta
     9661 actcatatac aaatcgaata gaaatgcctt atttaagatc accgattgta catcacgtac
     9721 atccacaacc gttccatcta aaacaattcg ctaaacagca ccaatataca aatgcttttt
     9781 atggtcctta tcaacgacct gaattgacaa tgtttatgaa tcatattgca catgcttcta
     9841 aacaatatca attagaggat tgcttggttc aaggtttagt tcaaacttta gataaacaag
     9901 aagacaaatg gcatatcaag ttagaagatg gacaaattat cactacagat tgcgtcgtta
     9961 ttgcaatagg tagtacaaat attccgttta tgcctgacat tttaaaagac aaacagaatg
    10021 taaatcatat cttcgagaaa gaacatgatc aagtagtata cgataagacc gatcatatcg
    10081 ttggtagtgg cattactgct gcacatcttg cacttaaatt gttaaatcat gataacgata
    10141 aaaagattca tttatggcta aataaagata ttgaaataca tgactttgat gctgatcctg
    10201 gttggttagg tccgaaaaat atgtcttcat ttttaagtac taaaagcatg cctgaaagaa
    10261 atgccattgt acaacgtgaa cgtcataaag gatcaatgcc tcacgaactg tacttacgcc
    10321 ttaaaaaaca tattaaaaat ggtcgtataa atgtgcataa aacacctatc actcaaatta
    10381 gtggtggtgt aattaacact gaaaatgatt ctgttccata tcaacagatt atggttgcaa
    10441 ctggttttga acaagatttt atgtcacaac cacttattaa gcaattaata caaaattatg
    10501 atgcacctat caacgaatgt aattaccctg ttatttccga aaaattagaa tggataccaa
    10561 atctatttgt cgcaggatgc tttgcagact tagaattagg accatttggt agaaatgtta
    10621 tgggtggccg taaagctgcc gaacgcattg aacaagcatt tctaaaatta caacaatata
    10681 gcgcataaaa aaactgctag ccgtagttat gaatatctca taacatttca gctagcagtt
    10741 cttttatttt aaaggtttaa tagcaactgt accacgcata actgtaatta attgttcttt
    10801 gtcattctta atttttatat cccatacatg tgtcgactta cctcgatgaa taatttcagc
    10861 tgtcgcagta acacgaccat ctttagcaga atgaatatgg ttagcattca tctctaaacc
    10921 taatggaata aatttggttg tatcaattaa attagcagat cctaatgaac atgctgtttc
    10981 acctaaagca atcgaagccc caccatgtaa atatccaaat ggttgtttta ctttatcagt
    11041 gacaggcata gaaataacaa ctaaaccatc ttcctggtga tctattgaca tctcaaatgt
    11101 ctctaataaa tgagtcatat tttcacctct ttatgcttat agtaccatag cagcaatagt
    11161 accgaaaatc attaaaggaa tattataaaa caagaagttt ggtacacatg tatcgcgtat
    11221 atgatcatgt tggccatcaa catttaatcc cgcagttggt cctaatgttg aatcacttgc
    11281 aggtgaacct gagtcaccta atgcactcgc tgttccaatc aatgcgatta atgccattgt
    11341 atctagtcca attgacgctc caaaaggaat gaataatgat gcgataatag gaattgttgc
    11401 aaatgatgat ccaataccta aagtgacaat taaacctatc acatacatca tgataatgct
    11461 aaataattta ttatcaccag taatacttgt taaagtttta actaattcat ctatatcacc
    11521 agtagcattc attacaccag caaacccatt tgctgttaaa ataactacac caatataagc
    11581 cataatttta ataccttcaa caaacttagc atctaattca taccaattat atgcacgtga
    11641 aataaagaat acgagtaccc ctgccagtgc accaaaaatc attgaatctg taaatgtttg
    11701 tactaaaaat gtagctagta ttgccacaat tgttactatt aagatatatg gttttaactc
    11761 tgtaacattg tcactatctg aaattttacg tgtttcatat tcacgtggtt tacgatatac
    11821 atataaaccg ataagtaagc caacaatata ccccattgaa ggaataagca ttgctttcca
    11881 aatcatatta aactcaattg ggtgattcgc ctttgcaaag ccactttgaa taatttgctg
    11941 gaaaatttga ccgaatccat atggtaataa cacatacggg aaacataaac caaaaccgat
    12001 aatcaaaccg attaaacgtc tatctatttt taagtcatta aacagactta acaatggtgg
    12061 gatgacaatt ggaatgaatg caatatgtac aggaattaag ttttgactca tgatactcat
    12121 agctaataat gcaatgatta ttgtcacttt tactttaact cttgaccatc gactattttc
    12181 agcgtgaatt gcatttataa tttttcctac taaatagtct gtgataccac tgtatgaaat
    12241 taatgctgca aatccaccta ataatgcata gcttaatgct acctcagcac catcgactat
    12301 atttttccca aatacattta taactttttc aatgctcatg cctgaaatta agccaccaac
    12361 tagcgcactg ataaataagc ttataactac gtttaatcga cataaacata gcacaatcat
    12421 taatattact gctattacta ctgcatttat catatgataa ccatccttta tcgctctatc
    12481 gaactaaagc gtttatagac tacatagtat cagtagcttt aacacctgtc aatagcaaac
    12541 tatacccata atctttattt tttagttaat tgtctttctt aaaataattt tcactttcat
    12601 taaattaaac aattttacaa gcctggaaca ccaatcaaaa tcctaagttc tataatgtta
    12661 tattagtagt cgttgactga atgagcatat gattataata agtttttgca atgctaatca
    12721 agttgattta tgctcacaag gatatgcgat ttatattttc ttacaacaat gaaaatgcct
    12781 gatacaatgc gatcctttat actttcaaga gttaaattag aaatgtataa caagacacaa
    12841 gttgtatcag gcaaataatt aaattattgt tgttttaacc attgtactat cgtcggaatc
    12901 ataaatcctg ttggcccttt tggaccatta tatgaagctt tattagtcgt tgctggacct
    12961 gcaatatcga aatgaatgtg aggtgtttga ccactaaaat gtgttacaaa acttgccgca
    13021 aatagcgctt taccttgtcc attcgtatgg ttaactaaat cagcgatatc actgtgatta
    13081 atacttgcac gttcggttgc agtaatcggt aattcaaata ccatttcatc gactttagaa
    13141 cttatttgta atatatcgtt taatatcact ttactattcg attcaaatgc agcagcttta
    13201 tcatcgccta gtgcaacgat ggctgcaccc gttaatgtag caaagtccat aatcacacta
    13261 ggctgatatt gatttgcata atacacagca tctgcaagga ctaatctacc ttcagcgtct
    13321 gtattcatta cttctacagt ttcaccactt aatgctgtaa atacatcatc tggcttcatt
    13381 gatgcttcat ttatcatatt ttcagcacaa gcaagcactc cgacaatatt tacaggcagt
    13441 tgtaaacgac tagccgcttc aatgatacca acgacattcg cagcgccaca catgtcaaac
    13501 ttcattgtag ccatgccatt cttcgtttta atactataac caccagaatc atacgttata
    13561 cctttaccaa ctaaggcaat tggtgctaca tctttgtctt tgccattata tgtgatggtt
    13621 actaatctcg gtttatgctt actaccttta cctactgctt gtaaaagtcc gaatccttca
    13681 gaaactaaag tgtcataatc tttaacatct actttgacct ttgtattttt aaaatgatta
    13741 acaatatctt ctgcaaatgt ttgtggtgtt aatacattcg gtggcatatt actaaagtct
    13801 cttgccaaat taatggattg gccaatactg ataccctcat gaatgaaatc taattcaatt
    13861 aatgattcac taataaggtt taaattcgtc ttaaacggtg ccttcttact tgatttataa
    13921 tgatcgaatt catatgttgc acgctcactt tgaataccgc atgccattaa tacatctgat
    13981 aactgatcat attttgaaat aaatgaatcc ataagtaaat aagtatcttc aatatgttct
    14041 gactttatgt attggaaaag atgtccccat attttcaaca tatcttgata actacgtgct
    14101 tttaagtttc ctaaaccaac tgtaattaaa cgatatgttt gatcttgtac atcaaatgca
    14161 gttgtataaa tcttcccaac tttactacca ataatatgtt gatgttttag tctttcaagt
    14221 gattctgtaa tatcgatatg attaaaacta atgcgctcta actgatttaa atgttctggt
    14281 ataccaataa tcaatgtatt tatttcgttg cttagtgtgt tatttaattt aaaattcata
    14341 atgtacctcc ttagatttga tatgttactc acttcaaatt gtacaacaat aaagcccttc
    14401 agtgacactg aaggacttta taaatgaata atttaatttt atgtgtttag ctgaaacttt
    14461 atttaaagcc tagaatttac cttttttgaa tgctaaaccg ataccaccga ttttgaatac
    14521 cgcacgtgta tcaatcactt ttttcatgaa tgctgctttt ttaccagcga taggtttacc
    14581 aaataccata cctacaccgt catgtgaacc taaagaacaa acagttccac gatcaacata
    14641 ttcgaattct tcagttgatt caccgtttaa gatgcgttta atgtttttag caacactttc
    14701 accttgttgc attgcaattt gtgctgtagt tggtaatgga cgttcttctc cagctgggat
    14761 aaacgctgaa cagtcaccaa taacaaaaat gttgtcgtaa ccattgattg ttaaatcttg
    14821 ctttgtaacg atacgtccac gtttaacgcc ttcaaatgat tcttccatta atttactacc
    14881 acgtacacca gctgcccata ctgaagtacc tgcatttaat tgttgttttt caccatctac
    14941 ttcaactaca aaaccttttt cgttacaagc aacgattggt gtagcaattt taaattcaac
    15001 accgcggtct tctaagtagc taactgcgtg gttaactaat tcttctgaga acattggtaa
    15061 cattttaggt gctgcttcaa cacaagtgat tttaacttta ttttgatcca caccatattt
    15121 gctacataat tcaggaattc tgtctgttaa ttcacctaag aattcaacac cagtgaatcc
    15181 agcaccacca actaagatag ataaatcgtt atcatctttt tcttttgatg ctgcatagtt
    15241 agcaaatttg tcttcgatat gacgtgataa ttcacgtgct gtgataacat tttcaatttg
    15301 gaaagcatga tctttcatac cttcgatgcc gaatgtttca ctaacgaaac ctaatgctac
    15361 tactaaaata tcaaagtcat aaataccttg atttgtttct acctttttag catcacggtc
    15421 aatttttgtt acttctgctt gaacaaagtt cactttgtct ttcttcaaga cactttccac
    15481 aggatataat acatcttcat agtttagtgt acctgctgat gcttcatgta accatgttgc
    15541 ttcatagtga tattcatttt tattaataag cgtaatttct gcttcttctg ttgatatcgc
    15601 tttttgcaat ttagttacag tttgtaaacc tgcataacca gcaccaagta caagtacttt
    15661 tttacgatct tgagccattt aatttcacct aagctttcat atttttttaa ccaaatgctg
    15721 ataattacta gtaacaactg gtcattacta cttttaccac aatgtatact agtttatcat
    15781 cattttgtta tttaagtctt ttaaattatg taaaaacctg tgatgttcac aaaaaagaca
    15841 tttttaatcc aatactaatt ctatagcttt tatgttatat tttcaagcaa gattcagtca
    15901 gattgtgaaa aaattaatta attttttcgt agcctgattt cgattaaaaa tgtatccgtt
    15961 atcacgatca tttaaattac tatttatagt cagattctta attttcaata agctttttaa
    16021 taaaacaaaa tatctttacg taaaaatagg acataatcaa atatgtccct aatcataatt
    16081 gatatcaatt tgtatcccaa aaattgggtt aaccattaaa aagttatttt attagcaatt
    16141 ttcaggatta cctgcaactt ttgcagttct aaatgaacta ccacagccac atgaagcaat
    16201 tgcattagga ttgtcgattt ggaaaccgcc acccattaat gattgcttaa aatcaatagt
    16261 cgtaccattt aatacgggtg catcttcttt gtctactaat acttttaatc caaagtattc
    16321 taagacttca tcattttcac caggcgcttc ttctgcaccc ataccgtatg ttaaaccagt
    16381 gcacccgcca ccattcactt taatttttaa atagccatct ggcatttcat ttgctttaag
    16441 catatctttt acttcgtagg cagctgcttc tgttaatata actgttggca tgataactcc
    16501 tccttaaaaa atccatgttt cttttatatg tgcatatata ttttgtaata attcttccgg
    16561 cgaatcacct tcaacaatat caccatttac taaagcatac aacccggctg aacatatacc
    16621 acaatgtgtc aggcaaccat actctaacac atcgacatct gggtcatttt ccagttgatt
    16681 aaaaacataa tctccacctt ttgccatgtt agagagacaa aattctacga tcggattcat
    16741 acttcacctt cttatttcat ttgttacaat attatagcat tttaaaactg gtattttaac
    16801 atgatgtgct caattaccaa caactgatgt ttcttatccc agttatgtaa tagtgcctta
    16861 gttagtacaa atatttattt gtagtcattt tcaaaaaaat atataataag catataaata
    16921 catatttact tttttagggg ttattgatga atcaaagaca cttgcatttt ataactgttc
    16981 attaacaaat atatctatgc actttgatct tttcaaaatt aaagtaaata ttaacatata
    17041 aaaggggtac ttcattatga aaaacttagt tttgttaggc ggcggatatg gtaatatgcg
    17101 tatcatgtca cgcattttaa ctacttcttt accacaagat tatacagtca cattagttga
    17161 tcgtatgcca tttcatggat tgaaaccaga attctatgct ttagctgcgg gcacgaaatc
    17221 agataaagat gttcgcatga aattccctaa tcatccacaa gtgaatacag tttatggtga
    17281 aattaacgac atagatttag atgctcaaat tgtctcagtc ggtaattcta aaattgatta
    17341 tgatgagcta atcattggtt taggatgtga agataagtat cataacgttc caggagccga
    17401 agaatataca catagtattc aaacactctc aaaggctcgg gatactttcc atagtattag
    17461 tgaactacca gaaggtgcta aagttggtat cgttggtgct ggattaagtg gcatagaact
    17521 tgccagcgaa ttaagagaaa gtagatcaga cttggaaata tatctttatg accgtgggcc
    17581 gcgaatttta agaaattttc cagaaaaatt aagtaagtat gttgcgaaat ggttcgccaa
    17641 aaataatgtt accgttgttc caaattcaaa tattaataaa gttgaacctg gtaaaatata
    17701 taactgtgat gaacctaaag atattgattt agttgtatgg acagcaggaa ttcaacctgt
    17761 tgaagttgtt cgtaacttgc cgattgatat aaatagtaat ggacgcgtga tagttaacca
    17821 gtatcatcaa gtaccaacat atcgtaacgt ctatgtagtt ggtgattgtg ctgatttacc
    17881 acatgcgcca agtgctcagt tagccgaagt tcaaggtgat caaattgccg atgtgcttaa
    17941 aaagcaatgg ctaaatgaac cattacctga caaaatgccg gaactaaagg tacaaggtat
    18001 cgttgggtca ttaggagata aacaaggttt tgcatatatc atggaccgca ctgtaacagg
    18061 acgactcgct tctattttaa aatccggcgt actttggtta tataaatatc ataatggtta
    18121 aaattaaaaa gcaatgtcag ttcacactat tactgacatt gctttttgtt atgtgtatat
    18181 tattcattca caagcttttg gtctataaat cgagtgattt gctttgtttg tatataacca
    18241 tctgctacat attcatcgtt cattgtaatt aatggataaa atagttcatc ttgttctatt
    18301 ctttcaataa attgtaaatc atgatctgtt aagttgtcat tatcttttgt aatatctata
    18361 tacgtatatt taaatgatat atttgggtat tttcttttta atagcggctg tagccagtca
    18421 taaatatctt tcgatgttgg cgcattaacg caacttgcac atataacatc tgccccatat
    18481 actaccacac tcacgtgctc catatattta tcccccattg gtttgataga tttttattac
    18541 actatctatt ataatatact aataaagatt atcaaattca tctctcgaaa ggagacttgc
    18601 ctgatgccta ctgaagatac aacgatgttt gatcaagtag cagaagttat tgaacgtctt
    18661 cgtccatttt tattacgtga tggtggcgac tgctcattga ttgacgttga agacggtatt
    18721 gttaaattac aattacatgg tgcatgtggt acatgcccaa gttctacaat cactcttaaa
    18781 gctggtattg agcgtgcatt acacgaagaa gtgcctggtg taatagaagt agaacaagta
    18841 ttctaatata aagatattaa gttaacagaa catattatga ataacaacaa agacaggaat
    18901 actgaattat ttataatcag ttattacctg tcttttttcg ctgtcaaatt ggactgatgg
    18961 gaaagttatt ttatactatt tatctgatta attattttat tattgccaca tatccaagca
    19021 catattacta ttctattcta tgaaatttaa aatataaaaa tagcacatac gctcaatcaa
    19081 aatcgttgag ttatgtgcta tttgtatttt aatttttagg tttatctact tcaggttgtg
    19141 gttcaccttt catatgtttc gcaatttgct catccatata aacccaacct ttccaaccga
    19201 tgtgtacggc atcactgata acatattttt cataatcttt atcagtcata tcgtaaattt
    19261 taccaccatt atctacaaca gtagaatgga tttttttata aactgcttga cgacgttctt
    19321 tatcgatacc aatgtggtca taccatacac cgtttgatgg aatacttaca tattgaacat
    19381 ctgcaccagc agcacgcatt gtttttacaa gtaattctaa atcttggaat tctggagaat
    19441 taacattgaa ttcgtagtca cgtctaactt tacgcttact ttcttgaatt aatttccagt
    19501 attgatctct aataccaaat ttattcgatg tagtatcagc tttaccaatt tcaactgctt
    19561 tttgtttcat ctcatcccaa gaagcgtctg gttttgtagc aggtttaaca tgttctaatg
    19621 gagatttatc cattgcaaac aatgatttaa tcgcttctat tttaatcaat tgattctctt
    19681 taaaaccaga aatataacta tctttagttt ctttagggtt tttagcataa gatttcaagt
    19741 attctttatt gtgtacatgt ggaaactgta ataaacgttg tgcataacga cgttttaatt
    19801 cagtagacat gtttttctgc tggaacattt gattaatttg agtttgagac atacgagcat
    19861 caaagttttg attcgttaaa ccatggtttg taaaccattg tggtgaaata ataaatgtta
    19921 atttcttacc ttttaattta tcatactgtg atgcaagttc aactgcgtta attaagtctg
    19981 tagaaccacc agcacctaat aagaatgctt ttttgttggc gttatgctta tttaatgcaa
    20041 ttgcaggatt aaatgggtca tctttaccta attcactaga gccgtatata ggataatact
    20101 tgtttgattc gtataactta tcttgaatga gtgtgccttt tagtacttga tctgtcaatg
    20161 aagttctatt atcttctaca gtcttttcat ttactaatcc tgtaaaccaa ctagcaggta
    20221 ataatagaaa gacaatgaat accgctccac taattaaaat gggtaaaaaa ggttttaatt
    20281 tcatcgtaac tcttctaatg cttcaacgat tttatttggt gttgcccact catctctatc
    20341 aaagtccata atagatactt cgatatcaag tttattttga atctctaata ataatccaac
    20401 tgtttggaaa gaatcaataa taccttcttc aaaaatttct acgtctggat tttcttttac
    20461 aatatcattt tctgctactt ctgctaataa atttaatact tgttctctaa attccataat
    20521 taaattctcc tttattatat aagtttacct gagaagatta aaaagccaaa tgttacaaag
    20581 tggaatgtaa tcacaatgct aagtgctgtt gtgaaaccat tttgccaacg tggcggatgt
    20641 ttcttacgcc aacgttcata atagccataa cctataaaca atgctgcatg gtataaacca
    20701 taaacaatgt aatacacttc gataccatgc caaattccca ttatgaagaa gttgattaag
    20761 aatgccacgt tagacattgc aaattgactc ttcaataatt ttttacgaga catgtagaat
    20821 aaagatctca tgtaaataca atctctgaac cagaatgata atgtcatatg ccatctattc
    20881 cagaaatctt taatattttt cgctttgaaa ggtttatcga agtttggtgg tgttttaata
    20941 ccgaataaat aactaaatgc tatcgcaaat aaactataac ctgcaaagtc aaagaataaa
    21001 tataagctgt atgcgtacat atataaccac aaattgacaa agccatgtaa gtctaattgt
    21061 aacggcatga ttgcatatgt gttaataaag taagcaacaa tatatttata caagaaacca
    21121 agcataatca tgtgaattgc ttttaatact aattcacgat attcattgcc tgttggtact
    21181 tttttatcgt ctttaacgaa acgtttgtaa cgatcgattg gtccagatga aatcgttggg
    21241 aagaatgaaa taaattgaat taatttccat actttaattt ctttgataga accatcacga
    21301 atttccataa ttaactgcac acttttgaat gtaacataag aaattcctaa gaaaccaaca
    21361 aattcaatta atttactttc atggaagtga atctgatgtc cacctaacca tgtactttgt
    21421 aacactttca caagtgctaa tggcaatatt gataaaacca ttacagttac aaattttgaa
    21481 aatgaattat tttttggttt tgaatgataa taaaacatta tcaataaaac ttgccatacg
    21541 acgtaaataa taaaactaat taattgaaca cttaaatact tttggtcaaa cagattatgt
    21601 ttatcagaag aaaagattaa cacaatcata aatgctgtaa ctacgccatt ataaatgtaa
    21661 cttcgcttac ctaaaaatcc aagtataatg actggtaata atgcaattaa agcaattaag
    21721 aagaatgtaa aatcaccata tggaatcatc cgttaattac ctctgcaatt ttctttctgt
    21781 caattttacc atttgaagtc aatggcaatt gttccatcca ttcaaacttt ctaggaatca
    21841 tatactctgg taagcgtgat ttcaagtcat ttttaatatt tttagtcatt tctgcattgt
    21901 ccgtaacttc agtcgttggc acaattgcac caattaaatg aataacttta tcatttttat
    21961 atacaggtac aacaatcgct tcttttacga actcagactg gcgtaattgt gtttcaattt
    22021 cttctaattc cattctgtag ccattcaatt tgatttggaa atcaatacga ccttgaatga
    22081 accattgacc attttcaaac ttcgctttat caccagtgtg atatgtacga ataccgtcat
    22141 cgaaattaaa tacttcagct gttttttggt cattttttaa gtatcctaaa cttacacttt
    22201 gaccttcaat aacaagttca ccgtcatctg tagtagataa tcttgcgcct agtctttcaa
    22261 cgccaacagg taatgtcgga tattgatcta agatttcttg tgtaatttga atacttgtaa
    22321 ctgctaccgt agcttcagtt ggaccatatg tgttgtaaat cgtcgcactt gggaaacggc
    22381 tcactaacgc ttttgctgct ctgtgaggta gaatttcacc acagaagaag aattcgttaa
    22441 gactaccata ttgttcttca ttaagcgttg gtaataataa acacatttcc ataaatgatg
    22501 gtgttgatac ccaaatgtta atcggtgttg ctgttagcat ttcatttaat aatttaggtt
    22561 tattaatcat gtttttatct acaagattta atgtaccgcc tgatgctaaa catggataaa
    22621 tagccattac agataaatca aatgaaaatg gcgcttggtt aagccattgt tgtttatttc
    22681 ctgatttatt aagttctaac atccactcag taaattgaac taaacttgca tattcaattt
    22741 gaacaccttt aggttcccca gtagaaccag atgtaaagat tgtgtatact gtgtcgttat
    22801 ctttaatctg actatcaaaa attactgggt cttgagatgt tttaatatct tcaattgtaa
    22861 atacttcgcc ttctaaactt tcaaatgatt catcagtcgt attaaataca aactctgctt
    22921 gaaccttgtt aataatcatt ttaatacggt cttcaggaat tgaagtgtct acaggtacat
    22981 atccacatcc tgctttaatg gcaccaatca tcccaacaat catatatggt gacatgtgac
    23041 cgaataaaat catcggtttc ttactacctt gtaatcgatg tgctaattta ctagactcat
    23101 ccattaactg ttgataagtt aattcatcag ttgtgtgtct aacagcaatg ctttgtggat
    23161 ttgcatccgc aaacgcttgc agcttgttaa taatatctgt catattaagt ctccctcatt
    23221 agaactcatt ataaatgaag ttattgtgtg tgtcgccact gccataaatt aaatataaag
    23281 taataaatat tgccaaatac aatagtgtta ataaatatgg tttgaatgct tcaacatatt
    23341 tattaggtgg ctgtttactt ttagatttca tattgcacct cttaaagttc ttagtaaaaa
    23401 cgcctttata aagaccgttc aatataaaat acgttttaaa atttgttttt tacaattcat
    23461 tatatcgata ttcataatga aattcaattt taattttata gattcaacat agtaattggt
    23521 tgtcatcact caattattgt aaatgataca ctttgttgag aacatcattc attttaaagg
    23581 ttatttaaac aataaacaat tacagtctat ataacaattt tgttatatac gtcaaaatca
    23641 aataaactca tcacattaat atgacgagtt tataatgtta ttgaattatc atcagcgcaa
    23701 atatatacat tcgcaagtca agcataacat atttaacaat tgctttgctt gttttaccaa
    23761 tgattaaaaa ccatacttat tttcaattta ctggagtatg tggtacctga tttgtcataa
    23821 ccgcttctat attattaata cataattgaa tcatattgtc ccgtgttgtt actgatgcgc
    23881 taccaatgtg tggtgtaatc agaacattat cacgtcccat taatggatgt gtatgatcaa
    23941 tcggttcatt tgctaataca tctaaaccac atgctaaaat ttctttattg tctagtgcat
    24001 cgattaatgc tgtttcatct acaatttgcc ctctaccgat attaataaaa attgcatcat
    24061 ttttcatttg ttcaaatgct tcagcattaa atttatgatg tgtttctttt gtaagtggcg
    24121 ctgtacagat gataaaatca ctttctgcta acaacgtttc aaaagaaaca tatgttgcat
    24181 taaagtccgc ctctgcatct ttatgtcttg atcgattatg ataaagaata ttagtattaa
    24241 acccttgcaa ccttcttgca aaagctttac caatatctcc cataccatat attccaatag
    24301 ttgaattgaa gacatcttta cctgacaata aataaggacc ccagctttgc catgcatctg
    24361 cttctacata tttttcagct tctacaatac ggcgtgctat agcaagcatt aatgtaaatc
    24421 ctaattctgc agttgtttca gtaagtacat ttggtgtatt cgtgacaacc acgttattcg
    24481 ctgttgcact ttcaacatcg atgttgtcat atcctacagc catattcgca attactttta
    24541 aatttggtga ttgtgctaaa atttctgcat cgatctgttc acttaatgta ataaaacaag
    24601 catctgcgtc acgaagtgct gtcacaaatt gatctttagg cataggcact aatgattttt
    24661 gccacataac aacgtcacca agtttactta attgttgata aaatttatct ggaattttcc
    24721 tcgaaacaac tatttttacc aaatcaattc acctacttta taaaatgact atatctattt
    24781 ttctaattca gctattgctt catttaaatc tttaaaagaa tacgttggtg gcacattttt
    24841 attttgcaca tcttctaacg tagatacacc tgtttgtaca tgaatcgtat ccatacctac
    24901 gttaatacca gacataatat cggtatcgta caaatcgcct accatagcaa cttcggattt
    24961 atctaatcct aaaatttcta atgctttaac cataataatc ggttctggtt taccaataaa
    25021 ttgtggcgat acacctgtcg atacacttac aacacttgta atagcaccat taccaggtaa
    25081 taaaccacgc tctttaggaa ttgatacatc aggatttgta gaaataaatg ttgcaccatt
    25141 tcttacacct aacgttgcaa tcgcaagctt ttcatatgta acttgttcgt caagtccaat
    25201 aactacataa tcaacatgct cgtcattttt aatgacaagt cccgcttcgg ttaacgcagt
    25261 atttaaacca ctcccaccta acatatatac tgatgctcct ggtgattgtt ctgaaatata
    25321 atcagcagtg gctaacgctg acgttacaac ctcttctggt ttagcatcaa tatgcatttc
    25381 acgtaatttt tcagttactt gctcaggtgt ttttgttgaa ttattagtta cgtataaatg
    25441 aggaatgcct tttacattta aataatcgat gaattgtttt gctccatcaa tctcatctgt
    25501 tcccatatac attgtgccat ctaaatcgat taaatacgct ttatactgtt tcattattga
    25561 ttttctcctt taccaaaagc tgttactggt acattttctt gatgtaaaaa tatcgttact
    25621 tctgtaataa attgtttgta ataaggtaat gcgtcatcaa acattggcat gataacctta
    25681 atatctaagg ctgtgtaatc atatgtaaat tgtttacgaa tatcgacagt tttattaatc
    25741 tcctgctgtg tttctttagt aataacattt tctagttcta atatatcaat cacatcttta
    25801 taattaccag gatcccttaa aataaatgca tcgataatca tattccctat atctaccgat
    25861 gattctatca acatttgagc aatgcgttca aatgcataat gattgtgctt gctctcatga
    25921 taatcatcag ttaatgcttg taaataggct aatttctgag ttagtttatc tttgtctaca
    25981 aaatacattc cttgtcacct ctcgcttata tattatcata attttgcagt atacttcatt
    26041 tgtcgttata ctaactttac tacttttaaa aggagtcgct acaaaatgat tgatatgtat
    26101 ttatatgatg acaacgaaga gagtcaagtt cagtttgttg gttttgttgg cgagcatagt
    26161 cgatatgatt tgatgttagt ccatacaaat agacattatg gtaagacact cgtacttaat
    26221 atgcaaacaa ataaattcgg tattatcggt actgatgatt taaaagaaga aggctatatc
    26281 gctcatattt taggtgtaaa tgctgaagaa ggcgatgaaa ttactgagta tttaaatgaa
    26341 gtcattcatt aaggttctcc accaaatgtg gtgggtatat aatttaaaga actattttaa
    26401 attacaactt ttagagtttt tattattagg cggccagtcc attattgggc ttggttgtct
    26461 tctttttttc tcctttgtat aagctgaaaa tcatcattat acgtgcttta aa
//
LOCUS       DAPDIM010000039        26277 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000039 DAPDIM010000000
VERSION     DAPDIM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 26277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26277
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.039"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..129)
                     /locus_tag="RFE25_001701"
     CDS             complement(<1..129)
                     /locus_tag="RFE25_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816758.1"
                     /translation="MKRIVILENVIVDNPIWLKHVDYLVKSVLLKSIKLRFQEVRKF"
     gene            complement(257..760)
                     /locus_tag="RFE25_001702"
     CDS             complement(257..760)
                     /locus_tag="RFE25_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDU2816759.1"
                     /translation="MSKWIIVSDNHTESGVLYQIYEMHPDADVYLHLGDSEFAYDDTE
                     LSLFNRVKGNCDFYPEFENEAVAKYNDVKAFYTHGHLYQVNRTRDLLAEKGLELGCLF
                     AFYGHTHVAKYEYINGVHVINPGSISQSRSSMEETYAEVIIDDQTLHGTINFKNRHHE
                     TISHTTF"
     gene            complement(753..1340)
                     /locus_tag="RFE25_001703"
     CDS             complement(753..1340)
                     /locus_tag="RFE25_001703"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HDU2816760.1"
                     /translation="MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGST
                     FEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLL
                     NKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKL
                     DKTMAQLSKEQKGQISHRRNAINLLQAFLEGEKNV"
     gene            complement(1352..2152)
                     /gene="racE"
                     /locus_tag="RFE25_001704"
     CDS             complement(1352..2152)
                     /gene="racE"
                     /locus_tag="RFE25_001704"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDU2816761.1"
                     /translation="MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPR
                     PGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTA
                     IMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTI
                     TSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSAL
                     LTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND"
     gene            complement(2389..3204)
                     /gene="sdhB"
                     /locus_tag="RFE25_001705"
     CDS             complement(2389..3204)
                     /gene="sdhB"
                     /locus_tag="RFE25_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit"
                     /protein_id="HDU2816762.1"
                     /translation="MTEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEI
                     PYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNCLEEVCGACSMVINGRARQSCSA
                     IVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEK
                     KRQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNA
                     LMGTGGLQQCGNSQNCVNACPKGIPLTTSIAAMNRETTFHMFKSFFGSDHEVE"
     gene            complement(3204..4970)
                     /gene="sdhA"
                     /locus_tag="RFE25_001706"
     CDS             complement(3204..4970)
                     /gene="sdhA"
                     /locus_tag="RFE25_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HDU2816763.1"
                     /translation="MAEKHLIVVGGGLAGLMSTIKAAEKGAHVDLFSVVPVKRSHSVC
                     AQGGINGAVNTKGEGDSPWIHFDDTVYGGDFLANQPPVKAMTEAAPKIIHLLDRMGVM
                     FNRTNEGLLDFRRFGGTLHHRTAYAGATTGQQLLYALDEQVRAYEVDGLVTKYEGWEF
                     LGIVKGDDDSARGIVAQNMTTAEIETFGSDAVIMATGGPGIIFGKTTNSMINTGSAAS
                     IVYQQGAIYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKY
                     PDYGNLVPRDIATREIFDVCINQKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEK
                     FTGDDPRKVPMKIFPAVHYSMGGLYVDYDQMTNIKGLFAAGECDFSQHGGNRLGANSL
                     LSAIYGGTVAGPNAIDYISNIDRSYTDMDESIFEKRKAEEQERFDKLLAMRGTENAYK
                     LHRELGEIMTANVTVVRENEKLLETDKKIVELMKRYEDIDMEDTQTWSNQAVFFTRQL
                     WNMLVLARVITIGAYNRNESRGAHYKPEFPERNDEEWLKTTMASFQGAFEKPQFTYDD
                     VDVSLIPPRKRDYTSKSKGGKK"
     gene            complement(5022..5636)
                     /locus_tag="RFE25_001707"
     CDS             complement(5022..5636)
                     /locus_tag="RFE25_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b558 subunit"
                     /protein_id="HDU2816764.1"
                     /translation="MAQSKNEFYLRRIHSLLGIIPIGAFLVVHLLVNHQATQGAEAFN
                     KASNFMESLPFLIIVEFLFIYIPLLYHGLFGIHIAFTAKENVGHYSIFRNWMFFFQRV
                     SGILTFIFIGIHLWQTRLQKAFYGKEVNYDLMHETLQHPGWAIFYIICIIAVVFHFAN
                     GLWSFLVTWGGLQSPKSQRVFTWVSLIVFLVISYIGVTAIIAFM"
     gene            complement(5960..7741)
                     /gene="uvrC"
                     /locus_tag="RFE25_001708"
     CDS             complement(5960..7741)
                     /gene="uvrC"
                     /locus_tag="RFE25_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499646.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDU2816765.1"
                     /translation="MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRL
                     RSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSY
                     PFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
                     LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDF
                     ERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRD
                     TTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARG
                     PKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNI
                     QGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLP
                     DLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNS
                     QAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKM
                     KEATLEDFKNIGIPENVAKNLHEQLHK"
     gene            7907..8002
                     /locus_tag="RFE25_001709"
     CDS             7907..8002
                     /locus_tag="RFE25_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816766.1"
                     /translation="MLDYHLTFIDLLIPPFSSRKQYDDLSFNFLY"
     gene            complement(8065..8379)
                     /gene="trxA"
                     /locus_tag="RFE25_001710"
     CDS             complement(8065..8379)
                     /gene="trxA"
                     /locus_tag="RFE25_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDU2816767.1"
                     /translation="MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAA
                     DYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDK
                     HL"
     gene            complement(8552..10900)
                     /locus_tag="RFE25_001711"
     CDS             complement(8552..10900)
                     /locus_tag="RFE25_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDU2816768.1"
                     /translation="MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVV
                     FQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQF
                     KTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFHQINETCDTYDLYDNASYELQGIRS
                     KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQS
                     ASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQ
                     LDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVII
                     TGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLST
                     FSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTH
                     YPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINK
                     AKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYE
                     KSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEA
                     KSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLE
                     KKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIH
                     GKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK"
     gene            complement(10910..12622)
                     /gene="polX"
                     /locus_tag="RFE25_001712"
     CDS             complement(10910..12622)
                     /gene="polX"
                     /locus_tag="RFE25_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="HDU2816769.1"
                     /translation="MTKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPL
                     DEISDVTELKGIGKGVAEVINDYRETGESQYLQQLQEEVPEGLIPLLKIQGLGSKKIA
                     KLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRR
                     LNQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVK
                     EVAVGNTKVSLELAYDDETIGVDFRLIEPRAFYHTLQHFTGSKEHNIRIRQLAKARDE
                     KVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFDKDLSNIITLDDING
                     DIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIK
                     ALDKEYSEIDIYSGTEMDILPDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLA
                     NACRNPYVRHIAHPTGRIIGRRDGYKPNIEQLMALAEETNTVLEINANPHRLDLNAEI
                     VRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKDFIENNI
                     KLKK"
     gene            complement(12695..13216)
                     /locus_tag="RFE25_001713"
     CDS             complement(12695..13216)
                     /locus_tag="RFE25_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HDU2816770.1"
                     /translation="MVIDFIIIIFFVYFVIVGFRRGFWLSMIHLSATIVSLWIASQFY
                     KSIVERLIVFIPYPKTTAFNTTFAFHFNHLQNRFEAIVAFLMITLFCKFILYLIIVTF
                     DKIIAYQNIHIFSRAMGMIVGVFMTIIVLHFTLYLLALYPNEALQHQLKISIVSHSLI
                     FHIPYLSAFTINL"
     gene            complement(13217..13483)
                     /gene="zapA"
                     /locus_tag="RFE25_001714"
     CDS             complement(13217..13483)
                     /gene="zapA"
                     /locus_tag="RFE25_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDU2816771.1"
                     /translation="MAQFKNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGY
                     KAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHKLQQREQ"
     gene            13853..14791
                     /locus_tag="RFE25_001715"
     CDS             13853..14791
                     /locus_tag="RFE25_001715"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HDU2816772.1"
                     /translation="MANIVFKLSDKDITTLMSRITFDTENLPQGMKARAKYQNTTVNI
                     YQSGKVMFQGNHAEAVSKELLPQHSQLNTNKTKKKNMANSSLEQTLMYDQFNCIGSDE
                     AGSGDYFGPLTVCAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVAFIPHSLLT
                     LHNDKYNIQQAKGWTQVKMKAVLHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYA
                     LSDIPLPKKTKFETKGESKSLAIAVASIISRYAFITYMDQISKYINMTIPKGAGAKVD
                     VIAAKIIKKYGLSRLDTISKKHFKNREKAQKILKPL"
     gene            complement(15223..17625)
                     /locus_tag="RFE25_001716"
     CDS             complement(15223..17625)
                     /locus_tag="RFE25_001716"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDU2816773.1"
                     /translation="MLISNEWLKEYVTIDDSVSDLAERITRTGIEVDDLIDYTKDIKN
                     LVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYVIVAKVGGRLPGG
                     IKIKRAKLRGERSEGMICSLQEIGISSNYIPKSFESGIYVFSESQVPGTDALQALYLD
                     DQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETTSNELELSANDELTVTIENE
                     DKVPYYSARVVHDVTIEPSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQ
                     DAIGSQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPIALAGVMGGDFSEVKE
                     QTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYA
                     NGKVLKDRVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDV
                     ITVLVPSRRKDITIKEDLIEEVARIYGYDDIPSTLPVFDKVTSGQLTDRQYKTRMVKE
                     VLEGAGLDQAITYSLVSKEDATAFSMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAAS
                     YNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQGKKETVDFYL
                     AKGVVDRVSEKLNLEFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPTLAADNDLK
                     RTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIALEVDQNIPAADLLSTIHAHGGN
                     ILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQGAV
                     IR"
     gene            complement(17625..18683)
                     /gene="pheS"
                     /locus_tag="RFE25_001717"
     CDS             complement(17625..18683)
                     /gene="pheS"
                     /locus_tag="RFE25_001717"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDU2816774.1"
                     /translation="MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGL
                     MKLMKDLPNEEKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGR
                     HIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDS
                     FYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGL
                     VVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCN
                     VCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYT
                     NDVRFLDQFKAVEDRGDM"
     gene            complement(19063..19803)
                     /locus_tag="RFE25_001718"
     CDS             complement(19063..19803)
                     /locus_tag="RFE25_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDU2816775.1"
                     /translation="MEQITSAQNNRIKQANKLKKKRERDKTGLALIEGVHLIEEAYQS
                     GIVITQLFAIEPARLDQQIIAYAQEVFEINMKVAESLSGTVTPQGFFAIIEKPHYDIS
                     KAQQVLLIDRVQDPGNLGTLIRTADAAGMDAVIMEKGTTDPYQDKVLRASQGSVFHLP
                     VMTQDLDTFITQFNGPVYGTALENAVAYKEVTSSDSFALLLGNEGEGVNPELLAHTTQ
                     NLIIPIYGKAESLNVAIAGSILLYHLKG"
     gene            complement(20043..20150)
                     /locus_tag="RFE25_001719"
     CDS             complement(20043..20150)
                     /locus_tag="RFE25_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816776.1"
                     /translation="MVLLAFVTTIHDTDDGRFFNEHKHANNKLLKHSLI"
     gene            complement(20187..20510)
                     /gene="isdG"
                     /locus_tag="RFE25_001720"
     CDS             complement(20187..20510)
                     /gene="isdG"
                     /locus_tag="RFE25_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylobilin-forming heme oxygenase IsdG"
                     /protein_id="HDU2816777.1"
                     /translation="MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTL
                     EQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIG
                     YSYMK"
     gene            complement(20529..21263)
                     /gene="srtB"
                     /locus_tag="RFE25_001721"
     CDS             complement(20529..21263)
                     /gene="srtB"
                     /locus_tag="RFE25_001721"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HDU2816778.1"
                     /translation="MRMKRFLTIVQILLVVIIIIFGYKIVQTYIEDKQERANYEKLQQ
                     KFQMLMSKHQEHVRPQFESLEKINKDIVGWIKLSGTSLNYPVLQGKTNHDYLNLDFER
                     EHRRKGSIFMDFRNELKNLNHNTILYGHHVGDNTMFDVLEDYLKQSFYEKHKIIEFDN
                     KYGKYQLQVFSAYKTTTKDNYIRTDFENDQDYQQFLDETKRKSVINSDVNVTVKDKIM
                     TLSTCEDAYSETTKRIVVVAKIIKVS"
     gene            complement(21325..22290)
                     /gene="isdF"
                     /locus_tag="RFE25_001722"
     CDS             complement(21325..22290)
                     /gene="isdF"
                     /locus_tag="RFE25_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin ABC transporter permease protein IsdF"
                     /protein_id="HDU2816779.1"
                     /translation="MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTG
                     SNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRA
                     LCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLE
                     ILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGF
                     NIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGA
                     WLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNRI"
     gene            complement(22303..23181)
                     /gene="isdE"
                     /locus_tag="RFE25_001723"
     CDS             complement(22303..23181)
                     /gene="isdE"
                     /locus_tag="RFE25_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HDU2816780.1"
                     /translation="MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALT
                     MTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDE
                     MQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKA
                     AKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLN
                     INPDIILRLPHGMPEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDA
                     DKAMTQLYDLFYKDKK"
     gene            complement(23178..24254)
                     /gene="isdD"
                     /locus_tag="RFE25_001724"
     CDS             complement(23178..24254)
                     /gene="isdD"
                     /locus_tag="RFE25_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated surface determinant protein IsdD"
                     /protein_id="HDU2816781.1"
                     /translation="MRNVKQIATKSIIAIISLCILTYTTMIGSVLADEIKYPSAKFNQ
                     PEAKDKTELTTSIFDEKIKENKALELLIFNQENKNVTEEQQLVDEKAQLISDMTGKIY
                     LQVKLKGQIDKEQLVFQNDKNEEFPFVIKDEKDDTIVRILIEQHMDKINMHVKTLAEK
                     KNLDNKEMVYSIHFKEKKVQHDDAKEVPSKHQNQENNQDQLKKDIDDKKDSQKSDTKE
                     RRTSLFTEKGLNDIPVQKDKVQQDSNKKIENERPKASGTLKVENSPPTIKKVENNHKE
                     QPKHKDEKSKKEKKKVVEKEKALPAFNRDDDSKNSSQLSSDIKELDEPNHKKQYMLFA
                     AGIVLATILLISAHLYSRKRGNQV"
     gene            complement(24254..24937)
                     /gene="isdC"
                     /locus_tag="RFE25_001725"
     CDS             complement(24254..24937)
                     /gene="isdC"
                     /locus_tag="RFE25_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme uptake protein IsdC"
                     /protein_id="HDU2816782.1"
                     /translation="MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTN
                     DTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTS
                     EFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKN
                     SASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFV
                     RKKSKGNVE"
     gene            25146..26198
                     /gene="isdA"
                     /locus_tag="RFE25_001726"
     CDS             25146..26198
                     /gene="isdA"
                     /locus_tag="RFE25_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored heme-scavenging protein IsdA"
                     /protein_id="HDU2816783.1"
                     /translation="MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQV
                     NAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYY
                     FQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIV
                     VPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEK
                     VKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVAT
                     AKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSVDNFISTVAFATLA
                     LLGSLSLLLFKRKESK"
BASE COUNT         8241 a         4952 c         3597 g         9487 t
ORIGIN      
        1 aaatttcctg acttcttgga atcttaattt tatacttttt aataatacac ttttaaccaa
       61 ataatcaaca tgtttcaacc atatagggtt atcaacaatc acattctcca aaattacaat
      121 tcttttcata acataaatgt gttattcatt ccaattatct tataaaattg tcagaaatac
      181 ttttaaacaa acattcatga cacgacctcc tagttaaatc agtctataaa ctaaaaaaag
      241 ccatagctac ttctatttaa aaagtagtat gactgattgt ttcgtgatgt cgatttttga
      301 aattgatggt gccatgtaaa gtttgatcat caataataac ttcagcatat gtttcttcca
      361 ttgaacttct agattgagat atacttccag gattaataac atgaacacca ttaatatact
      421 catattttgc cacatgtgta tgtccataaa atgcaaacaa acaacctaat tcaagtcctt
      481 tttcagctaa taaatctctt gttcgattga cttgatataa atgtccatga gtataaaatg
      541 ctttcacgtc attatatttt gcgaccgctt cattttcaaa ttctgggtaa aaatcacaat
      601 tgccttttac tctattaaat aagctaagtt ccgtatcatc atacgcgaat tctgaatctc
      661 ctaaatgtaa atatacatct gcatctgggt gcatttcata aatttgatat aaaacgcctg
      721 attcagtatg gttatcactc acaataatcc atttagacat ttttttcacc ttcaagaaaa
      781 gcttgaagta aattaatcgc atttcgtcta tgactaattt gccctttttg ttcttttgaa
      841 agttgagcca tggttttatc taatttcggt acataaaata tcggatcata tccgaaacca
      901 ttttcgccat attttccatc tgcaatttca cctgaaacag tacctttaaa tacttttgtt
      961 tccatatcag ggccactcat acttatgaca caaacaaatt gcgcacgacg atcagttgta
     1021 ttaccaagct tatttaataa tttttcaata tttgcttcat cgcttttatt ttcaccagca
     1081 taacgtgcag agtatatacc tggctcacca tttaatgcaa aaacttctag tccactgtca
     1141 tcagctatga cagttttatt caatgctttt gcagcagctt ctgattttaa tatagcattt
     1201 tcttcaaatg ttgatcctgt ttcttccaca tcaaaatctg gtattagttc tgaaatacct
     1261 attacgtggt aatctggaaa tattacttta aagtcattta ttttcccttg attattcgat
     1321 gcaataacaa tctctttcat taaaaatcct cctagtcatt cactgatata cgttccacat
     1381 tgacagataa atttaaccac tctttgataa tgttagtaat gtgagtagga tcacctgttg
     1441 caaaaaatcg atgatctgga tgttcagtat aacttgcatg ttcattacta aatgttagca
     1501 atgcactaac ttcacgagcc gtttctaatc cagacgaaat cactgtcttt ttaccaccaa
     1561 aataatcata gataggttta tagagcaatg gatagtgggt acatcctaaa atgacagtat
     1621 cagactcact attacgccaa cgtttcagtg tttgatgaat gacaatgctt gtaattgttg
     1681 gatcactata tctcatttgt tctacaagtg gcacaaaacc tggacaggca acgccatgta
     1741 cctctacatg tggattgata cgtttaatat gcgtacgata tgcttcagat ttaattgtgc
     1801 cttcagttcc tagtactaat acattttgat ttctagtagt cattattgct gttctagcac
     1861 ctggttcaat tacaccaatc actgggattg ataaggtctt ttgtaaatat tctaaagcta
     1921 cagcagttgc tgtattacaa gcaatcacga gcatttttat atcaaattcc attaatttac
     1981 gagcgatttc aactgtatat tgttttactt gttctcctgg tcttggccca tatggacatc
     2041 gtccaatatc acctaagtaa taaatcgtct catttggcaa ctgacgcata atttctttag
     2101 ctactgtcaa acctccgaca ccagagtcta ttacacctat tggtttattc atattcggtc
     2161 atccttactt ttaatttaat ttttagttta tcataactaa gcattggatt ttagtattat
     2221 gcactgtgtt taccattttt gtcattataa tatttatttt aaatcagccc actatcatat
     2281 tgtcatgtaa tctgcttatt aaaaaaaatc ccttccaagt tattgtgtat ctccattcaa
     2341 tttaattttg aaaggaacat aacattttaa ctcaaaaggg attaattttt attctacttc
     2401 atggtctgaa ccaaagaatg atttaaacat gtggaatgtt gtttctctgt tcattgctgc
     2461 aatggatgtt gttaatggaa tacctttagg gcaagcatta acacagtttt gtgaattacc
     2521 acactgctgt aagccaccag tacccattaa tgcatttaaa cgttcatctt tagtcataga
     2581 tcctgttggg tgcaaattaa acaaacgaac ttgcgagatt gcttgtgcac caacgaattt
     2641 attattttca gtaacattag gacaaacctc taaacataca ccacatgtca tacatttaga
     2701 taattcataa gctgtttgac gttttttctc tggcatacgt ggtcccggac ctaaatcata
     2761 cgttccatca attgggatcc atgctttcat acgttttaag ttatcgaaca ttctagaacg
     2821 atcaacttgt aagtcacgga taactgggaa agtattcatt ggctctaaac gaataggttg
     2881 ttctaattga tcaacaatcg cagaacaaga ttgtcttgca cgaccattga taaccataga
     2941 acatgctcca catacttctt ctaagcagtt catatcccag acaacaggtg ttgttttttc
     3001 acctttaata ttaactgggt tacgtctaat ttccattaaa caagcaatga cgtttaaatt
     3061 ttcacgatat ggaatttcaa atgtttcttc ataaggctta gaatcacttg tatcttgtcg
     3121 tttaataatt aattttactg ttttttgttt cggtttagat tgtgtttcat gttgtggagt
     3181 gtttttcact gattgttcag tcattatttt ttaccccctt tagacttact tgtgtaatca
     3241 cgtttacgag gtggtattaa actcacatcg acgtcatcat aagtaaactg tggtttttca
     3301 aatgcgcctt ggaatgaggc cattgtcgtt tttaaccact cttcatcatt acgctctggg
     3361 aattctggtt tataatgggc accgcgtgat tcgttacggt tatatgcacc aatcgtaata
     3421 acacgtgcaa gtactaacat gttccatagt tgacgggtaa agaataccgc ttggttactc
     3481 caagtttgag tatcttccat atcaatatct tcataacgtt tcatcaattc aacaatcttt
     3541 ttatctgttt ctaacagttt ttcattttca cgaacaacag ttacatttgc tgtcataatt
     3601 tcaccaagtt cacggtgtaa tttataggca ttttctgtac cgcgcatagc taataattta
     3661 tcaaaacgtt cttgctcttc agctttacgt ttttcaaaaa tactttcgtc catatcagta
     3721 tatgatcgat caatatttga aatataatca atcgcgtttg gacctgctac tgtaccacca
     3781 taaatcgctg ataacaatga attggcacct aagcggttac caccatgttg agagaagtca
     3841 cattctccag ctgcaaataa ccctttaata tttgtcattt gatcataatc tacatataga
     3901 ccacccattg aatagtgaac agctgggaaa atcttcattg gtactttgcg tgggtcatca
     3961 ccagtgaatt tttcataaat ttcaatgata ccacctagtt ttacatctaa ctcatgtgga
     4021 tctttatgtg acaaatcaag atataccatg ttttcgccat ttatacctaa tttttggtta
     4081 atacatacat cgaaaatttc acgcgttgcg atatcacgag gtactaagtt accataatca
     4141 ggatatttct cttctaagaa gtaccaaggc ttaccatctt tatatgtcca aattcgtcca
     4201 ccttcaccac gtgctgattc actcattagt cgcagtttat catcaccagg gattgcagta
     4261 ggatgaattt gaatgaactc accattagca taaatagcgc cttgttggta aacaatggaa
     4321 gccgctgatc ctgtattaat cattgagttt gttgttttac cgaaaataat accagggcca
     4381 cccgttgcca taataactgc atctgaacca aatgtttcaa tctcagcagt tgtcatattt
     4441 tgtgcaacga tacctcttgc actatcatcg tcacctttaa ctatgccaag aaattcccat
     4501 ccttcatact tcgtaactaa tccatctact tcatatgcac gaacttgttc atccaatgca
     4561 tataataatt gttgtccagt tgttgcccct gcatatgctg ttctgtggtg taatgtacca
     4621 ccgaaacgtc taaaatctaa tagaccttca tttgttctat tgaacattac acccatacgg
     4681 tctaataaat gaataatttt aggtgctgcc tctgtcatcg ctttaacagg tggttggttt
     4741 gcaaggaagt cgccaccata cactgtatca tcaaagtgaa tccaaggaga atcgccttcc
     4801 cctttagtat tgaccgcacc attaatgcca ccttgggcac aaacagagtg cgaacgcttt
     4861 actggtacaa ctgagaacaa atctacatgt gcaccttttt ctgccgcttt aattgttgac
     4921 attaagcccg ctaggccacc tccgacaaca ataagatgtt tctctgccat aaaaatttca
     4981 ctcccctaaa ttttcaatct atatttgtta aatgcgatgt attacataaa ggcaataatt
     5041 gcagtaacac caatatacga aataactaaa aatacgatta atgaaaccca tgtaaatact
     5101 cgttgtgatt ttggagattg aagtccaccc caagtaacta agaatgacca taagccattt
     5161 gcaaagtgga acacaacagc aataatacaa ataatataaa atattgccca tccaggatgt
     5221 tgcaatgttt cgtgcattaa atcgtaattc acttctttgc cgtaaaatgc tttttgtaaa
     5281 cgtgtttgcc ataaatggat accaataaag ataaatgtta agataccact cactctttgg
     5341 aagaagaaca tccagtttct aaaaatcgag taatgtccaa cattttcttt tgctgtaaat
     5401 gcaatgtgta taccaaacaa accgtgatat aacaacggaa tgtatataaa taaaaattct
     5461 acaataatta gaaatggtaa tgattccata aagttagatg ccttattaaa cgcttcagca
     5521 ccttgtgttg cttggtgatt cactaataaa tgaacgacca aaaatgcacc tattgggata
     5581 atacctaata acgagtgaat acgtcttaga taaaattcat tttttgattg agccaaaagg
     5641 agtcccccct gtgaacgaat atttaattta ttgagctatt tatattaaac gtacgcttaa
     5701 ccccctaaag tgatatcgtt tctagcgttg tcattatcat taagcgaaac attttaaaga
     5761 caaatacaca ctgtacgatc accaaactgc atgtcgaaca atgtaacatt tggattcgat
     5821 atttaaaatt gcttgtgatg ataaactttc tcatttagaa aacgcttcca cgtacattca
     5881 aaaaaataac tttgttaacc atattgtaac attatttcat atattttggg gcatgagaat
     5941 gattctcacg cccagtaatt tatttatgca attgttcatg taggttcttt gcgacgtttt
     6001 caggaatacc tatattttta aaatcttcaa gtgtagcttc cttcattttc ttgattgaac
     6061 cgaatgaacg caataataat gttttacgtt tgttaccgat accatctata tcatcaagta
     6121 ttgatttcaa gcctgtcttt tgacgtgttt gtctatgaaa tgtgattgcg aatctgtgaa
     6181 cctcatcttg gatacgatgc aacaaataaa atgcctggct atttttcttc agtggtacaa
     6241 tttctgcact agcgccatat aataattcag atgtttggtg tttatcattt ttctgcaaac
     6301 ctgcaacagg gatatcaaga cctaattcgt tttgtagcac atcaataacc ccgttcatat
     6361 gtcctttacc accatcgact attattaaat caggtaatgg taatccttcg tttaaaacgc
     6421 gagaatatcg tcgtcttact acttctctca ttgatttgta atcatctgga cctttaaccg
     6481 ttttgatttt atactttcta taatttttct tatctggttt accgtcgaca aatgtaacca
     6541 ttgctgacac tggatccaca ccttgaatat tagaattatc gaatgcttca attctaattg
     6601 gtgtttgaat tcccatttgt gttccaagtt cttcaatagc tttaatcgtt cttgactcat
     6661 cacgtgatat taattcaaat ttattattta aggatacttt agcgttatgt gcagctaggt
     6721 caaccatatc ttttttggga cctcgcgcgg gttgaacgat tttagtgtcc acaacagatt
     6781 gaatcatttc tttatccaaa ttacgtggta catgaacttc cttaggtaaa atatgttggt
     6841 ttaagctata aaattgtcca ataaatgtat aaaattcttc ttcttctgtt tgctgtaatg
     6901 gaatcatcgt tgtatctcgc tttatcatat taccttgtcg tataaagaaa acttggatac
     6961 acatccatcc tttatcaaca caataaccaa agacatcacg aatcgtttta tctgatgaca
     7021 taattttttg tttgtttgtc agattttgaa tatgttgaat taaatctcta tattctttag
     7081 cccgttcaaa atcaagtgat tcacttgcag ttaacattcg ctcttctaaa ctttttaaaa
     7141 ttgttttgtc ttccccattc agaaaatcag taatttcctt cgtcatttgt gcgtatttac
     7201 tcaaatcaac gtcatataca catggtccta aacattgtcc aatatggtaa taaagacata
     7261 atttatctgg catcttatca catttgcgat atggatatat tctgtctaat aactttttag
     7321 tttcttgagc agaatatgca ttcggatacg gtccgaaata tttgccagta ccttgtttta
     7381 cagttctcgt cactagtagt ctaggatatt tctccttcgt aattttaata aatggataac
     7441 ttttatcatc ctttaataat atattatatc ttggttgata ttgttttatc agattcaatt
     7501 ccagtaaaag tgactctgtt tcacttgacg tgacaataaa ctcaaaacga cgtatttcac
     7561 caaccagtct cgttgtttta gcatcatgag cacccgtaaa atatgatctc aatcgatttc
     7621 ttagcttttt agctttgcca acatatatca cttgatcatt acgatctttc attaaatagc
     7681 agcctggttc cataggtacg acatttaatt tatttttaat tcgttgctta tagtcttcca
     7741 aaaatatccc cccttctaat tttaaaatga atgatgctac aaaagtgctt caaatttatc
     7801 accactaatt ctagctcata atcaacatct tcgagtatga cttttcatgc acatcatgta
     7861 atattgaaca tggttttatc aaaccaactg ctacaaatct atcagcatgc tagattatca
     7921 tttaacgttc atagatttat taatcccacc attctcaagt cgtaaacaat atgatgactt
     7981 atcattcaac tttttatatt aaaaacacaa acaaaaactg gagcaattca ttaaagaaat
     8041 gccccagtcg tcattggtta taacttataa atgtttatct aaaacttcag ctaagttttc
     8101 ttttggttgg aaaccaacaa ctttatcaac tggttgaccg tctttaaaga cgattaatgt
     8161 tggaatactc atcacttcat atttagctgc agttgatgga ttttcatcaa catctaattt
     8221 taaaatgtca gctttacctt catagtcagc tgctaattct tctaataccg gagcgatcat
     8281 tttacatgga ccacaccatg ttgcccaaaa atctactagt tgtacaccag attctacttt
     8341 tgaatcaaaa tctgcatctg ttacttttac gattgccata aatgccaatc ctccttaatt
     8401 attattatga tgttcaaatt atatcagata acatgcttca tgtatttcta tttgctcaat
     8461 ttttatgctt atttcaaata acatgtttga aatgtattct tgttgcttta cattatttta
     8521 actgcagcta tttaatttat caaattataa tttattttag tgttgcaacg gtaacgccaa
     8581 atccaccttc gcttggcata ccacctctaa agtcactaac acttttatgc ttcttcaaat
     8641 gttgttgtac acctttttga agtgcacctg tacctttacc atgaatgata taaacttgtt
     8701 cgtaattact taaaacggct tgatctaaat attgatctag ttcaattaaa gcatcctcat
     8761 aacgatagcc tcgtaagtca agttcagttt taattgtttg acgattttga cgtgtaacca
     8821 ttttcgttgg cttaactttt tctttttgtt ttttctctaa atcttcaata ggtaacttca
     8881 ttttaataat tcccatttga acaattgctt cttcatcatt gacaatttct aaaacttcac
     8941 ccttttgacc gtaagataat acttttactt catcaccagc aacaatttta tcgtattttt
     9001 gcttttgtac attttgcttt atagatttcg cttcataatg atcatctaat cgtttcttct
     9061 tatcaatcaa ttcatgttct ttaacatctg cacctttttg ttcacgcaat tgtcttaagt
     9121 ctttaataat atcgtcagct tcttttgttg cagctttaat cttctgattt gctttttctt
     9181 tcgcttcctc tattagagac ttttcataat tttggaattg ttgatactgc ttagataaat
     9241 catcatgcac ttgctccgct tcttttacaa gacggtccag ttctaacctc tgtgtctcta
     9301 cacgtttata attacgctct aatgattcaa tcatttcatt tatttctttt tcatcagtac
     9361 caatcatcgt cttagcctta ttaataatat tcaaactaag acctaacttt ttagaaatgt
     9421 caaaagcatt tgaacgaccc ggcacaccca ttaataactt atacgttgga ctcaaagtat
     9481 ctacatcaaa ttctacactc gcattcataa cgccttctcg attataacta tatgctttaa
     9541 gttcaggata gtgcgtcgtt gccattacta gagaaccaat ttttctaaca tgatctaaaa
     9601 tgctcattgc taatgcagca ccttcacttg gatctgtacc tgcacctaat tcatcaaata
     9661 aaactaaact atgtttgtct gcatgcttta aaatttcaac tatattcgtc atatgagatg
     9721 aaaaagttga taatgattgt tctattgatt gttcatctcc gatatcgcaa tatacatttt
     9781 taaatacact taactgacta ccatcaagtg tgggaatcaa caatcctgat tgagccataa
     9841 caataattaa acctaatgtt tttaatgtta cagttttacc acctgtattc ggtcctgtaa
     9901 taattaccgt ttcaatatct tccataaatt cgatggtatt agctacaaca gtctcacgat
     9961 ttaataatgg atggtatgct ttaggtaaat atacagtacg ttcctcttta aatatcggct
    10021 ttgttccttt aatacttcta ctatatctcg cttttgcgat taaaaaatct aactgcccca
    10081 tgacttgttc tgccacaagt agtgcatctt tgtccgcagc cacataacca gttagttgcg
    10141 ttaaaatgcg ttctttttca attgcttcgt catgacgtaa tcgactaatt tgattattca
    10201 tttcaacaac tgatgatggc tcaatataca atgtttgtcc tgaagcagat tgatcatgta
    10261 caatcccatt aaaatcttgt cgatattcag ctttgacagg tataacgttt ctttcattcc
    10321 taactgttac aatagcatct gataattttt tctgatttgc ttggctttta acaatacggt
    10381 ccaaattttg tctaatacgt tgattcgtgc tagaaatttt acttctaatc ccttgcaatt
    10441 cataactcgc attatcatat aaatcatacg tatcgcatgt ttcatttatt tgatgaaaaa
    10501 gatcagttaa cacaggtaat tgattcatct tgtcatctaa tattgggtat ttaacacctt
    10561 catcttcttc aaccaattga ttataaaatg tcttaaattg attttgtact tgaattaatc
    10621 tttttatcaa gttaagctct gatacattta aaacgccgcc aatatcagcg cgatgaatga
    10681 atgctgatac tttagataag ccactcaagc ttggtaaacg atgcttatta tagatttgag
    10741 caatctcatc cgtttcttcc atttgaaaaa caaccgtttc aaaattagta gctggcatca
    10801 tttgattgac cttttccaag cctaagtcac taatagtttc attggcaacg agtgatttta
    10861 ttttttcaaa ttctaagacg tctaatgttt tttgtctcat aaaatccctc tatttcttaa
    10921 gttttatatt attttcaata aagtctttaa aagcttcacg cgataatgcg ttaatcactc
    10981 tatcttttgt tacaaatcct ttttgcgcag ttgctacgcc ataattcata aaatctaaat
    11041 gatttgtatg atgcgcatca gtgttaatag ttaatttcac atttggatat ttacgaacga
    11101 tttcagcgtt cagatccagt cgatgtggat tggcattaat ttctaatact gtattcgttt
    11161 cttcagctaa tgccattaat tgttcaatat tcggtttata accatctctt ctacctataa
    11221 tacgccctgt tggatgcgct atatgtcgca cgtatggatt gcgacatgca ttagctaatc
    11281 gttccataat ttgttcttct gattggttaa agctttgatg aatagctcca attacataat
    11341 caagttgtgc taaaatttca tcatcataat ccagcgagcc atcaggtaat atatccattt
    11401 ctgtacctga ataaatatca atttcactat attctttatc taaagcctta atttcttcgt
    11461 tttgtcttaa aagtctttcc acttgtaagc cattagcaac acgtaaactt tgtgaatgat
    11521 cagtaattac catgaattta taaccttttg cgatatttgc ttctaccatg tctcgaatag
    11581 aaaacgcacc atcactatac gttgtatgca tatgaatatc accattaata tcatctaatg
    11641 taatgatatt acttagatct ttatcaaatt cgctaccatc ttctcgcata gcaggtggta
    11701 taaaattcac attaaaatgt tcatatatct tggcttcact atcatattga attaatgtac
    11761 catcagcttg ttcaattcca tattcactta ctttttcatc acgtgcttta gcaagttgtc
    11821 gaattcttat attatgttct tttgacccag taaaatgttg caatgtatga taaaaagccc
    11881 ttggttcaat taatcgaaaa tcgacaccaa tcgtttcatc atcatacgct aattctaatg
    11941 aaacttttgt gttccccact gcaacttctt ttactttatt gggaatattt aataattgct
    12001 gctgcactgc ttttgggtta tcggtactta ttatgaaatc taaatctttg ctcatttctt
    12061 taaaacgacg gaagcttcct gcagatgaat attgatcgat ataatttaat gtatctatat
    12121 aatcaatgat ttcttgatta agtcttctca tttgatcaat tggatatcta tctttcttag
    12181 caccaagttg tttcacagct tctaatatgt tttgttccgt tttcttagca aatccgctta
    12241 attcactaac ttttccattt tcacaagcaa cttgaagtga cgctttatca acaatattca
    12301 actctttata tagcttagca attttcttgc ttccaagtcc ttgaattttc aaaagtggaa
    12361 taagaccttc cggaacttct tcctgtaatt gctgtaaata ctgagattca ccggtctcac
    12421 ggtaatcatt gattacttct gcaacacctt taccaatgcc ttttaactcc gttacatcag
    12481 atatttcatc taatggtcgt tcatctaatt caagactttg agctgctttt cgatacgctg
    12541 atattttaaa agtattttcc ccttttaatt ccatataagt agcaatttgt tctaatagtt
    12601 tgataacatc tttttttgtc ataataacac tccataaaaa gaagaccagg acgtatcatt
    12661 aatatatacc tttgtcctga cctcttatga taatttataa attaatggtg aaagccgata
    12721 aatatgggat gtgaaaaatc aatgaatgac tcacaataga tattttaagc tgatgttgta
    12781 atgcttcgtt aggatataat gccaatagat ataacgtaaa gtgtaagaca attatcgtca
    12841 taaacacacc aactatcatt cccattgcac gactgaaaat atgaatgttt tgatacgcta
    12901 ttattttatc aaaagttacg ataattagat ataaaatgaa cttacaaaac aatgtaatca
    12961 ttaaaaaagc tacaatcgct tcaaatcgat tttgtagatg attaaaatga aacgcaaaag
    13021 ttgtattaaa tgctgttgtt ttaggatatg gaataaatac aattaatctt tctacaatag
    13081 atttgtaaaa ttgactggca atccacaatg atacaatcgt tgcactcaaa tgtatcatag
    13141 ataaccaaaa acctcgtctg aatccaacga tgacaaaata cacaaagaaa atgattatga
    13201 taaaatcaat gaccatttat tgctcacgct gctgcaattt gtgaatttgt tgtttcaaac
    13261 gtcgattttc ttcttctagt agtacttttt catgcataat attcacagca gttagtattg
    13321 cttttcttga agtatctaaa cctgctgctt tataccctaa ttcttttatt ttatcatcaa
    13381 ctaaatgtgc tacatatcgt atgtgctctg ggttatcttc cccaacaatt gtaaaaagct
    13441 gatcattaat tgatacattt accttgtttt taaactgtgc catttataat ttctcctgat
    13501 ccttttttta aaatctaaat tcacgttata aaatatgact ggatagtttg tctgaatttg
    13561 atactaatat tgttatattg caattatgat aaaacaacaa cacaatctct atagatgact
    13621 taatgttctt tttataatga aataatgtaa agaattttct attcaatact ttatcatgtt
    13681 taaattgtgt cactataaca ttttcataaa cattatacat gaccactatg tattttgtaa
    13741 gtatccgcaa ttaattcttt acaacataca taaatgtttc tgacgttatt atcatttatg
    13801 atatgattat ttttgctaat gataatgaaa ttatatgaaa ggatttacac aaatggcgaa
    13861 tatcgttttt aaattgtcgg ataaagacat aacgacatta atgtcacgca ttacttttga
    13921 tactgagaat ttacctcaag gtatgaaagc acgtgcaaag tatcaaaata caactgtaaa
    13981 tatttaccaa tcaggtaaag tcatgtttca aggtaatcat gcagaagctg tgtctaaaga
    14041 acttctaccg cagcattctc aattgaatac taataaaact aaaaagaaaa atatggctaa
    14101 ttcttctctt gaacaaactt taatgtatga tcaatttaac tgtattggta gtgatgaggc
    14161 tggaagtggc gattactttg gtcctttgac tgtgtgtgct gcttttgtta ccaaagagca
    14221 tgttcctatt ttaaaaactt tgggtgtaga tgattcaaaa aaattaaccg ataccaaaat
    14281 tgtagaactt gctgagcaat tggttgcttt catcccacat tcactattaa cactacacaa
    14341 tgataaatat aatattcagc aagcaaaagg ctggactcaa gtaaaaatga aagctgttct
    14401 tcataatgaa gccatcaaaa atgtacttga aaaaattgat tcgtctcaat tagactatat
    14461 cgtcattgat cagttcgcaa aacgcgaagt gtatagccat tacgcattat ccgatatacc
    14521 acttccaaag aaaacaaaat ttgaaacaaa aggagaatcg aagtcattag ccattgcagt
    14581 ggcaagcata atttctagat acgcatttat tacatatatg gatcaaatat caaaatatat
    14641 taatatgacg attcctaaag gtgccggtgc taaagtcgat gtaattgccg caaaaattat
    14701 aaaaaaatac ggtctttcac gtttagatac catttcaaaa aagcatttta aaaatcgtga
    14761 aaaagcccaa aaaattttaa agcctctttg atttttaatc attagaggct tttatgcagt
    14821 tgtgcgaagc atcatctgta ttccgctgtt cctctttgat ttataaaatg aattggatcc
    14881 taataggtga tcctattagg taagtcatac taatttgctt tgctcataag tatgacttta
    14941 tatgcagtga tgcgaagcat catctgtaat ccactgtgcc tctatgattt ataaaatcaa
    15001 gataaattgg atcctaatag gaaatcctat taggtaagtc atactaattt gctttgctca
    15061 taagtatgac tttatatgca gttgtgagaa gcatcatctg tattccgctg tgcctctttg
    15121 atttttaaat gaatcgaaac ctaattggtg aatccaaaaa taaaacccca tgttaaggat
    15181 atcaatctac ttcagatatc cttatacatg gggtttaaat cattatctaa taacagcacc
    15241 ttgttcaatt aatgctgctt caatttccgc ttgcactttt gaaacgcgct catctgtcaa
    15301 tgtttcttct gtgtctaaat aatttaaacg tattgcaatt gattttttac ctttttctaa
    15361 atgttcgccc tgatatacat caaagacaag tgtatctttt aatatattgc caccgtgtgc
    15421 atgaatcgtt gataataaat cagctgctgg aatattttga tctacttcta atgcaatgtc
    15481 acgagacatg cctgggaatc tcggaattgg ctggtaatta atgtaaccta ccgacacagc
    15541 cattaatgca tcaaaattca actcaaaaac atacgtacgt tttaaatcat tatcagctgc
    15601 taatgttgga tgtaattcac caataaaacc aacaacttta ttctctaata agatttcagc
    15661 agtacgacct ggatgtaatc catcaatatc agcacgacga taactaaatt caaggtttaa
    15721 cttttcagat actcgatcca cgacaccttt tgctaaatag aaatcaaccg tttctttctt
    15781 accttgccat tgattgacta cataatctcc agttaaaata ccacttaaat attcaacttg
    15841 atctggtagt tcaccttctc cattagcaaa gaagacattg ccgatttcaa ataattttac
    15901 atctttattt ttgcgtgcca cattatatga tgctgcttcg attaaatgtg gtaataaact
    15961 ttgacgtaat gacgcatgcg cttcactcat tggcatcaat aaatcaattg tttgacgctg
    16021 ttgcatcgaa aatgcagtag catcctcttt agaaactaac gaatacgtaa tagcttgatc
    16081 taatccagca ccttctaaca cttctttaac cattctagtt ttatattggc gatcagttag
    16141 ctgaccacta gtaactttat cgaagacagg taacgttgat ggaatatcgt cgtatccata
    16201 tatacgtgca acttcttcaa ttaaatcttc tttaattgta atatctttac gacgtgatgg
    16261 tactagcact gtaataacat catcatttat ttctgtatca aaccctagtt gattaaaaat
    16321 agtaacaata tcattttgtg acaaatcaaa tccaatagtg cgattaattt tatcagcagt
    16381 gatgtcgatt ggtgtaataa atgcaccaag ttctcctgaa gacactctat cttttagcac
    16441 ttttccgttt gcataagttt gtaataaata acatgcacgg tcgactgctt catctacaaa
    16501 ttcagtagct attccttttt caaaacgact agatgattca ctgcgtaaat ttaaacgtct
    16561 tgatgtatga cgaattgaaa ctggatcaaa aatagcacct tcaatcacta tatttgatgt
    16621 ttgttcttta acttctgaaa aatcgccacc cataacacca gctaatgcaa ttggagtttg
    16681 tccattagta atgacaatat cgctcgttaa taattcacgt tctgtatcat ctaatgttgt
    16741 cattttttcg ccttcattag cttgacgaac aacaatttgt tgtgaaccaa tcgcatcttg
    16801 atcaaacatg tgcaatggtt gaccgtattc taataacaca taatttgaaa tgtcaacaac
    16861 attattaata ggacgtatac ccgcttttat taagcgtgct tgcatccaaa ttggcgaagg
    16921 ttcaattgtc acgtcgtgaa caacacgtgc actataatat ggtactttat cttcattttc
    16981 aattgtcaca gtcaattcat catttgcaga taactcaagc tcatttgatg ttgtctctgg
    17041 cttagtcatt tttgtattat ataatgctgc aacttcataa gcagtaccta tcatacttaa
    17101 agcatctgca cgattcggcg ttaaatcaaa ttccattact tgatcatcta aatataaagc
    17161 ttgtaaggca tctgttcctg gaacttggga ttcactaaaa acataaatgc ctgattcaaa
    17221 acttttcggt atatagttac ttgaaatacc aatttcttgt aacgaacaaa tcataccttc
    17281 tgaacgttca ccgcgtaatt tggcacgctt aattttaata ccaccaggca atctgccacc
    17341 tactttagca acaatgacat attgtcctgc atcaacgttc ggtgcaccac atacgatttg
    17401 tacaggttcg tcttctccga tatcaacttg gcaaacattt aatttatcgg catcaggatg
    17461 tttctctttt gacttaacga aaccgacaac taaatttttg atatcttttg tgtagtcaat
    17521 taaatcatcc acttcaatac ctgtgcgcgt aatacgttct gccaaatcac ttacagaatc
    17581 atcgattgtt acatattctt tcaaccattc atttgatatc aacattacat gtcacctcta
    17641 tcttctaccg ctttaaattg atctaaaaat ctcacatcat tagtatagaa atgacgaata
    17701 tcttctatac catatttcaa cattgcaata cggtctggtc ccataccaaa tgcaaatcca
    17761 gagtactctg aagaatcaaa accagccatt tctaatacat taggatgtac cattccagca
    17821 cctaaaattt caatccatcc tgtgtgttta cacacattac aaccttttcc tttacattta
    17881 aaacatgaca catcaacttc tacagaaggt tcagtgaatg ggaagtaact tggacgtaaa
    17941 cgaatttcac gatcagcacc aaataatttc ttagctaaca attctaaagt gcctttcaaa
    18001 tcactcattt taacgttttt atcaacaact aatccttcga tttgtgtaaa ttgatgacta
    18061 tgtgtcgcat catcagagtc acgacgatac actttaccag ggcaaataat tttaactgga
    18121 ccttgaccat gacgtgattc catcgtacgt gcctgcactg gtgatgtatg cgtacgtaat
    18181 aaaatttcat ccgtaatata gaaactatct tgcatatcac gtgcagggtg tgatttaggt
    18241 aaattcagca tttcgaagtt ataatgatct tgttcaactt catatccatt cacaatttca
    18301 taacctaaac ctaagaataa gtcttcaatt tcttctattg tacgtgttaa tggatgcttt
    18361 gaaccgattt caatatgacg acctggtaat gatacatcaa ttgtttcttc agccaattgc
    18421 ttatttaatt tttctttaac taacatctgt tgtctttcat ctaattcatt ttgaattgtt
    18481 tgacgcaatt cattcacttt ttgaccaaac gcaggtttct cttcattcgg caaatccttc
    18541 atcaatttca ttagtccgct aactgaccct tttttaccta agtatttcac tttaacttct
    18601 tgcagtgcac gttcatcatt tgcttcatta atatctacaa gcgcttgttg ttttaactct
    18661 gacattgttt gttgttcaga catatgtcac tgacctccct attcgaacta ttcattttct
    18721 attgatcata tttgttgttt aactaaaaaa tgactttcat cctcttaaaa ataagggacg
    18781 aaagtcattt ccgtggtacc acccaaattt atgcctaagc atacacttgt ttaatattga
    18841 taacggattg tctttccgac ttaaatctct ttaagtaacc aaaaaggtga aaagacttta
    18901 aataattgga ataacttgca gtcacgatta ttctccctaa aacaattatt tatataaatg
    18961 tccatgcctt tttattggtt tatattcaat tgtgtatgca ttcacgtaga aatgttctgt
    19021 taaacaatta attataatta tatcggaaaa ctttcaacac ggtcaacctt tcaaatgata
    19081 aagtaaaata ctacctgcaa tcgctacatt taaactttca gctttaccat aaataggtat
    19141 gattaaattt tgtgtagtat gtgctaataa ttcaggatta acaccttctc cctcattacc
    19201 taatagtaat gcaaaagaat cacttgaagt aacttctttg tatgccactg cgttttcaag
    19261 tgctgtacca taaacaggac cattaaattg agtaataaac gtatcgagat cttgtgtcat
    19321 aactggcaaa tggaaaacac taccttgact cgctcgcaac actttatctt gataaggatc
    19381 tgtcgtaccc ttctccatta ttacagcatc cattccagca gcatccgcag ttctaattaa
    19441 tgtgcctaaa tttccaggat cttgaacacg atcgatgagc aatacttgtt gtgctttaga
    19501 aatatcataa tgcggcttct caatgattgc gaaaaaccct tgtggtgtca ctgtacctga
    19561 taaagattca gcaactttca tgtttatttc aaaaacttct tgcgcgtatg cgataatttg
    19621 ctgatctaat cttgccggtt caattgcaaa taattgtgta attacaattc cactttgata
    19681 agcttcttca attaaatgca caccttcaat taaagctaat ccagttttat ccctctcacg
    19741 tttctttttt agcttgttcg cttgtttaat tctattattt tgtgcagaag taatttgttc
    19801 cattgatagc tcctcgcttt atttttaaaa ataaaaatat taatcattaa taagatgaaa
    19861 acatttgatt gtatagttaa tattaattaa tcgcttttat cactcataat atttcaaatt
    19921 gcataaattt cttttatcga tactactact ataaatcata cgccccaaaa tatcattatt
    19981 aattcttttc ttcttcaaaa taaatcaaaa tgatataatt gatgattatt ttcaaagcac
    20041 attcaaatca aactatgttt tagcaatttg ttgttagcat gtttgtgttc attaaaaaaa
    20101 cgaccatcat cggtatcatg tatggtcgtt acaaaagcta acaataccaa ttgtcataac
    20161 aagtactgca acctctttaa attcaattat ttcatgtaac tatagcctat atcatatgta
    20221 attactttgt tattgataat cgggctactt tcatcttcat ttttacttct aacatgttta
    20281 tgcgctgctt taaagacatc agattttaac caatccgtaa aagcttgctt tgatttccaa
    20341 actgttaaaa ttttcacttc atcaaaatct tcttgttcta aagtttgtgt aacaaacatg
    20401 ccatcaaagc cttctaatgt ttcaatccca tgtctcgtgt aaaatcgttc tataatatct
    20461 tttgctgttc cttttgttaa cgtcagccta ttttctgcca taaatttcat aattatcctc
    20521 ttttcttttt aacttacctt aattattttt gcgacaacaa caattctttt cgttgtttca
    20581 ctatatgcat cttcgcacgt tgataaagtc attattttat cttttaccgt tacattaaca
    20641 tctgaattaa ttacagattt acgttttgtc tcatctaaaa attgttgata atcttgatca
    20701 ttttcaaaat ctgtacgtat gtaattatct ttagtagtag ttttatatgc actaaatact
    20761 tgcaattgat atttaccata tttattgtca aattcaatta tcttgtgttt ttcataaaac
    20821 gattgcttta aataatcttc taacacatca aacatcgtat tatcaccgac atggtgcccg
    20881 tataaaatag tattatgatt taaattcttc aattcatttc taaaatccat aaaaatacta
    20941 cctttacgtc gatgttctcg ctcaaaatct aaatttaaat aatcgtgatt tgtcttacct
    21001 tgtagtactg gataatttaa tgatgttcct gataatttta tccatccaac aatgtcttta
    21061 tttatttttt caagtgattc aaattgtggt ctcacatgtt cttgatgttt gctcatcagc
    21121 atttgaaatt tttgttgtaa tttctcataa tttgcgcgtt cttgcttgtc ttcaatatat
    21181 gtttgaacaa ttttgtaacc aaaaatgata ataattacaa ccaataaaat ttgtacaata
    21241 gttaaaaatc gcttcattct cataaaaatc ctcttttatt aacgacgttt cttcagtcat
    21301 cactaaacca gttgttgtac cgttttagat tcgatttcgt tgactttgac aaattaagta
    21361 aattagcatt ggaccaccga caatcattaa aatagcattg gctggaattt ctaaaggagg
    21421 ctgtatcact cgtcctaata aatcagccac taacaatagc catgcaccaa taactgtaga
    21481 aaacggaata agtactctgt aattgccccc aactagcttt ctaaccacat gtggcacaat
    21541 aatacctaaa aaggctagtt gtccaacaat cgcaacagtt gcacttgcta aaaatactgc
    21601 taataaacct gttaaccatc tgtaacgatc aatattaaaa ccgatacttc gcgcttgtat
    21661 gtcgtctaaa tttagtaaat tcaatttagg ggacaatagt aatgttaata ttaatcccaa
    21721 taatgctgat actgctaata tgtatacgtc gctccatatt ttcattgtta agccttgagg
    21781 aattttcatt aaagggtttt gagttaaaat ttctaaaaca ccatttaata atacgaataa
    21841 cgcaacacct actaatatca tacttacagc attgaatcta aatttagaat gcaacaatat
    21901 aattattaaa aatggtatta aacctccaat aaaacttaat aatggtaagt aaaagtacaa
    21961 ttgtggaata aacaacatac aaagtgctct cattataagt gcacctgagg aaacgccaat
    22021 gatattcgcc tctgccaaag gattttgtag tgctgcttgt aataatgctc cagaaactgc
    22081 taacattgcg ccaaccatca atgcaattaa tatacgtggc aatcgcaaat caatgattga
    22141 atccactgct tcattgctac cagttgtaaa ttttgtaaat aggtcattaa atgacaattt
    22201 aattgtaccg gttacaaacg aaatataagc agttgcgatt aaaatgacta acaaacataa
    22261 aaatagtagt ttctttttat tttttatcat catatcaact cactattttt tatccttata
    22321 aaataaatca tataattgag tcattgcctt atcagcatca acatttgctg taataccgaa
    22381 tggcacttcc tctaagtcat aaacatgatt atttttcaca gctttaaaat gtttccaaat
    22441 atcattttgt ttaaattctt tttgaaacat tttcttaact tcttcaggca ttccgtgtgg
    22501 taatcgtaaa ataatatctg gattgatatt caacaaattt tcagtattag acgaaatata
    22561 ttgacgatct ttcactttaa taacattttc tccacctgct attttaacta aatcaccaat
    22621 atatgattta tcagttgcta ctaaatagct acccggtaca cccattaata ttaatacttt
    22681 gggatgtttc ttttgtttag ctgctttatt ttcaattttt tgctttacag aatttaaatg
    22741 gtcatttaat tcttttgctt gtgctttacg attaaattga tcacctaatt gtgtaatcga
    22801 cttttgcatc ccttttaaac tatcaaaatc ataaaagtag cctttcatat ttaattgttt
    22861 gtaaaatggt tgcatttcat ctttaatcgt tgacacactc aaaacatgtg ttggttttaa
    22921 ctttttaaca gcttcaacat tcggctccat tggttgacca atttccggta catctttata
    22981 acgattaggc aatgtcttat atgacgtggg tttgccgaca attggtaaat ccaatttgtc
    23041 caatgtcatt gtcaatgcaa cagttgttgg tacgattctg aattcgccgg atttagttga
    23101 ttcttgagaa ctggaagatt gacagctggt taagataacg acgcttatca ctaaaatggt
    23161 taaatacttt atgattctca aacttggtta cctctctttc tgctgtataa atgtgccgaa
    23221 ataagtaaaa tagttgctaa cacaatgcca gctgcaaata acatatattg ctttttatga
    23281 tttggttcat caagttcttt aatatcacta gataattgac tactattctt gctatcatca
    23341 tctctattaa aagctggtaa cgctttttct ttttcaacta cttttttctt ttcctttttt
    23401 gatttttcat ctttatgttt cggttgctct ttgtgattat tttcaacctt ttttattgtt
    23461 ggagggctat tttcaacttt taatgtacct gatgctttag gtcgctcatt ttcaatcttt
    23521 ttattactgt cttgttgcac tttatctttt tgtacaggaa tatcatttaa tcctttttca
    23581 gtaaaaaggc tagtacgtct ttccttagta tctgattttt gactatcttt tttgtcatca
    23641 atatcttttt taagctgatc ttgattattt tcttgatttt gatgttttga aggcacttct
    23701 tttgcatcat catgttgtac ttttttctct ttaaaatgaa tagaatacac catttctttg
    23761 ttatctagat ttttcttttc agccaacgtt ttaacatgca tattgatttt atccatatgc
    23821 tgttcaatta aaattcttac tattgtgtca tccttttcat cttttataac aaaaggaaat
    23881 tcttcatttt tgtcattttg aaaaacaagt tgttctttat ctatttgacc ttttagcttt
    23941 acttgcaagt aaattttacc agtcatatct gaaatcaatt gcgccttttc gtcaactagt
    24001 tgttgttcct cagttacatt tttattttct tgattaaaaa ttagtaactc taacgcttta
    24061 ttctctttta tcttttcatc aaaaattgat gtagttaatt ctgttttatc ttttgcttca
    24121 ggttgattaa atttggctga tggatatttt atctcatcag ccaacacgct accaatcatt
    24181 gttgtatatg taagtataca taagctaata atagctataa tagattttgt agcaatttgt
    24241 ttaacatttc tcattattcc acattgcctt tagatttttt tctaacaaac aatgtgattg
    24301 cgattaataa tgctaaggat gcaactggta ttgcatatat atatgcaggt gtaccagcat
    24361 ttgtttgtgg attttctact ttgtctttat tcgaactatt agattcactt tgaccagtag
    24421 tcgttccatc agatcctttg tcactacctg aagcagaatt tttatcatct ttacctggtg
    24481 cattagcacc tgctacatca gttggtccat taaatttata tgtaatgttg taatgatggt
    24541 catatttgaa tggctttcca tttacttttt catcgatata aacgtcaatt tttccatcta
    24601 ttttaccgtt caacttactt acttcaaatt cagaagtgcg ttcatctttg gcagtgtttt
    24661 tactaataat attttcttta tgtccttcga tactcattcc agtaatccaa tgactgtggt
    24721 tgacagttat ttgaacatac aatttaccat ttttcttaat gtactttgcc ggtttattaa
    24781 aatagtcatt agcaattgac gtgtcattgg tattgtattt gtaaacctca taattcaaag
    24841 taccgctatc tgcggcattt gcagaattac tgaatgtcgc gatgatgata attaacgcta
    24901 aaatcgttgt attaaaaact tttaaaatat ttttcaaaac ataatcctcc tttttatgat
    24961 tgcttttaag tctttagtaa aatcataaat aataatgatt atcattgtca atatttattt
    25021 tataatcaat ttattattgt tatacggaaa tagatgtgct agtataattg ataaccatta
    25081 tcaattgcaa tggttaatca tctcatataa caacacataa tttgtatcct taggaggaaa
    25141 acaacatgac aaaacattat ttaaacagta agtatcaatc agaacaacgt tcatcagcta
    25201 tgaaaaagat tacaatgggt acagcatcta tcattttagg ttcccttgta tacataggcg
    25261 cagacagcca acaagtcaat gcggcaacag aagctacgaa cgcaactaat aatcaaagca
    25321 cacaagtttc tcaagcaaca tcacaaccaa ttaatttcca agtgcaaaaa gatggctctt
    25381 cagagaagtc acacatggat gactatatgc aacaccctgg taaagtaatt aaacaaaata
    25441 ataaatatta tttccaaacc gtgttaaaca atgcatcatt ctggaaagaa tacaaatttt
    25501 acaatgcaaa caatcaagaa ttagcaacaa ctgttgttaa cgataataaa aaagcggata
    25561 ctagaacaat caatgttgca gttgaacctg gatataagag cttaactact aaagtacata
    25621 ttgtcgtgcc acaaattaat tacaatcata gatatactac gcatttggaa tttgaaaaag
    25681 caattcctac attagctgac gcagcaaaac caaacaatgt taaaccggtt caaccaaaac
    25741 cagctcaacc taaaacacct actgagcaaa ctaaaccagt tcaacctaaa gttgaaaaag
    25801 ttaaacctac tgtaactaca acaagcaaag ttgaagacaa tcactctact aaagttgtaa
    25861 gtactgacac aacaaaagat caaactaaaa cacaaactgc tcatacagtt aaaacagcac
    25921 aaactgctca agaacaaaat aaagttcaaa cacctgttaa agatgttgca acagcgaaat
    25981 ctgaaagcaa caatcaagct gtaagtgata ataaatcaca acaaactaac aaagttacaa
    26041 aacataacga aacgcctaaa caagcatcta aagctaaaga attaccaaaa actggtttaa
    26101 cttcagttga taactttatt agcacagttg ccttcgcaac acttgccctt ttaggttcat
    26161 tatctttatt acttttcaaa agaaaagaat ctaaataaat catcgtcaca ctcataactt
    26221 aatatatttt ttattttaaa ttttatttaa cctatgtcat agatatttca taatcta
//
LOCUS       DAPDIM010000040        25783 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000040 DAPDIM010000000
VERSION     DAPDIM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 25783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25783
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.040"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            140..691
                     /locus_tag="RFE25_001727"
     CDS             140..691
                     /locus_tag="RFE25_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUMOD4 motif-containing HNH endonuclease"
                     /protein_id="HDU2816784.1"
                     /translation="MNELWKDVVGYEGIYEVSSKGRVRTHKNKVTWSNRYQKWRHWKQ
                     RYLKDKTPNGRDVRVTLWKNGKRKDFLVHRLVAFAFIPMIEGKNCINHIDGNPKNNNV
                     ENLEWCNHLENNRHAFETGLMHTNMAVKLINHLGIEYEFISMSRAGKFLGRSHSYISD
                     KIKNNHKDVTDIHGNKYKFEKLI"
     gene            692..1366
                     /locus_tag="RFE25_001728"
     CDS             692..1366
                     /locus_tag="RFE25_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816785.1"
                     /translation="MPKITSYITQDDGTTTVVISGVELGNKETLLLDNGFDVEVDVNV
                     IDPFQITGKQRRKIFALVKDIEEHTGQPMDYMRHMFIEFVRTYYGYDERISLSNCTRT
                     QASQIIEATLDWTFYNDIPLSYKTSNLLKQDKSFLYWSTVNRNCVICGKPHADLAHYE
                     AVGRGMNRNKMNHYDKHVLALCREHHNEQHAIGVKSFDDKYQLHDSWIKVDERLNKML
                     KGEKNE"
     gene            1359..2114
                     /locus_tag="RFE25_001729"
     CDS             1359..2114
                     /locus_tag="RFE25_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDU2816786.1"
                     /translation="MNKLLIDDYPIQVLPKLAELIGLNEAIVLQQIHYWLNNSKHKYD
                     GKTWIFNSYPEWQKQFPFWSERTIKRTFGSLEKQNLLHVGNYNKAGFDRTKWYSINYE
                     TLNKLVARPSGQNGPTMRTNWHDARGQNDPTNTIDYTETNKHRETDDVSKSFKYISTN
                     LEIIQNPLKAEQLEHEIKSFKQDQFEIVKVATDYCKENNKGLNYLLTVLKNWNKEGVS
                     DKESAENKLKPRNSKKETTDDVIAQMEKELSDD"
     gene            2114..2470
                     /locus_tag="RFE25_001730"
     CDS             2114..2470
                     /locus_tag="RFE25_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816787.1"
                     /translation="MPMSKTQALEIIKKVRYVYNIDFDKPKLEMWIDVLSQNGDYQPT
                     VKAVDGYINSNNPYPPNLPAIMRKAPKKVSIEPVDNETATHQWKMQNDPEYVRQRKIA
                     LDNFMNKLAEFGGDNE"
     gene            2467..3708
                     /locus_tag="RFE25_001731"
     CDS             2467..3708
                     /locus_tag="RFE25_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDU2816788.1"
                     /translation="MNYGQFEIESTIIATLLKQPDVLEKIRVKDYMFTNEKFKTFFNY
                     VMDVGKIDHQEIYLKATKDKEFLDADTITKLYNSDFIGYGFFERYQQELLESYQINKA
                     KELVTEFKQQPTNQNFNNLIDELKDLKTITNRKEDGTKKFVEEFVDELYSDSPKKQIK
                     TGYKLMDYKIGGFEPSQLIVIAARPSVGKTGFALNMMLNIAQNGYKTSFFSLETTGTS
                     VLKRMLSTITGIELTKIKEIRNLTPDDLTKLTNAMDKIMKLGIDISDKSNITPQDVRA
                     QAMRHSDRQQVIFIDYLQLMDTDAKVDRRVAVEKISRDLKIIANETGAIIVLLSQLNR
                     GVESRQDKRPMLSDMKESGGIEADASLAMLLYRDDYYNRDEDDSITGKSIVECNIAKN
                     KDGETGIIEFEYYKKTQRFFT"
     gene            3705..3920
                     /locus_tag="RFE25_001732"
     CDS             3705..3920
                     /locus_tag="RFE25_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816789.1"
                     /translation="MNIMQFKSLLKSMYEETKQSDPIVANVYIETGWAVNRLLDNNEL
                     SPFDDYDRVEKKIMNEINWKKTHIKEC"
     gene            3924..4145
                     /locus_tag="RFE25_001733"
     CDS             3924..4145
                     /locus_tag="RFE25_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3269 family protein"
                     /protein_id="HDU2816790.1"
                     /translation="MPKEKYYLYREDGTEDIKVIKYKDNVNEVYSLTGAHFSDEKKIM
                     TDSDLKRFKGAHGLLYEQELGLQATIFDI"
     gene            4155..4580
                     /locus_tag="RFE25_001734"
     CDS             4155..4580
                     /locus_tag="RFE25_001734"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015978383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HDU2816791.1"
                     /translation="MEVHYSSKTNEWTTPQHLFDDLNEEFSFTLDPCSTDENAKCRKY
                     YTVKDNGLIQDWSEDIVFMNPPYGRSIKRWVKKAYEESLKGATVVCLIPARTDTTYWH
                     DYIFNKADDIRFLRGRLKFGDSKNSAPFPSAIIVYRGAQ"
     gene            4577..4981
                     /locus_tag="RFE25_001735"
     CDS             4577..4981
                     /locus_tag="RFE25_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HDU2816792.1"
                     /translation="MSKYNAKKVEYKGIVFDSKVECEYYQYLESNMNGANYDRIELQP
                     KFELQPKFGKQRPITYIADFSLWKEGKLVEVIDVKGKATEVANIKAKIFRYQYRDVNL
                     TWICKAPKYTGQEWMVYEDLVKVRRKRKREMK"
     gene            4986..5171
                     /locus_tag="RFE25_001736"
     CDS             4986..5171
                     /locus_tag="RFE25_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3113 family protein"
                     /protein_id="HDU2816793.1"
                     /translation="MQQQAYINATIDIRIPTEVDYQHFDDVDDEKDMLAKRLDDNPDE
                     LLKYDNITIRHAYIEVE"
     gene            5207..5257
                     /locus_tag="RFE25_001737"
     CDS             5207..5257
                     /locus_tag="RFE25_001737"
                     /inference="COORDINATES: protein motif:HMM:NF019388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816794.1"
                     /translation="MYRVTYNQMFKKWSEA"
     gene            5257..5511
                     /locus_tag="RFE25_001738"
     CDS             5257..5511
                     /locus_tag="RFE25_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HDU2816795.1"
                     /translation="MSIISNRKVDMNETQDNVKQPAHYTYGDIEIIDFIEQVTAQYPP
                     QLAFAIGNAIKYLSRAPLKNGHEDMAKAKFYVDRVFDLWE"
     gene            5511..5759
                     /locus_tag="RFE25_001739"
     CDS             5511..5759
                     /locus_tag="RFE25_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816796.1"
                     /translation="MTMTDNARKEYLNQFFGSKRYLYQDNERVAHIHVVNGAYYFHGH
                     IVPDWQGVKKTFDTAEELGIYIKQHGLEYEEQKQLTLF"
     gene            5772..6173
                     /locus_tag="RFE25_001740"
     CDS             5772..6173
                     /locus_tag="RFE25_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816797.1"
                     /translation="MKIKVKKEMRLDELIKWARENPELSKGKIFLAKSFSNGFVRFQR
                     NTNTCSISSFIPIDTPFIVEVEEEITEDTVFDRLFEVYELQEGACMSALHTSISINER
                     LENTFFPTKAFYILNDGLTMTLIWKDGRLVE"
     gene            6170..6517
                     /locus_tag="RFE25_001741"
     CDS             6170..6517
                     /locus_tag="RFE25_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816798.1"
                     /translation="MMLKFKAWDKDKKVMSIIDEIDFNSGYILISTGYKSFNEVKLLQ
                     YTGFKDVHGVEIYEGDIVQDCYSREVSFIEFKEGAFYITFSNVTELLSENDDIIEIVG
                     NIFENEMLLEVMR"
     gene            6514..6822
                     /locus_tag="RFE25_001742"
     CDS             6514..6822
                     /locus_tag="RFE25_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816799.1"
                     /translation="MTFTLSDEQYKNLCTNSNKLLDKLHKALKDCEEYKKQRYELIGV
                     IAKLRDCNKELEKKASAWDRYCKSVEKDLINKFGNDDERVKFVMELNNKIFMEDDTNE
                     "
     gene            6815..7051
                     /locus_tag="RFE25_001743"
     CDS             6815..7051
                     /locus_tag="RFE25_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1024 family protein"
                     /protein_id="HDU2816800.1"
                     /translation="MNNREKIEQSVISASAYNGNDTEGLLKEIEDVYKKAQAFDEILE
                     GMTNAIQHSVKEGIELDEAVGIMAGQVVYKYEEE"
     gene            7056..7598
                     /locus_tag="RFE25_001744"
     CDS             7056..7598
                     /locus_tag="RFE25_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP pyrophosphatase"
                     /protein_id="HDU2816801.1"
                     /translation="MTNTLQVKLLSKNARMPERNHKTDAGYDIFSAETVVLEPQEKAV
                     IKTDVAVSIPEGYVGLLTSRSGVSSKTYLVIETGKIDAGYHGNLGINIKNDEERDGIP
                     FLYDDIDAELEDGLISILDIKGNYVQDGRGIRRVYQINKGDKLAQLVIVPIWTPELKQ
                     VEEFESVSERGAKGFGSSGV"
     gene            7635..7871
                     /locus_tag="RFE25_001745"
     CDS             7635..7871
                     /locus_tag="RFE25_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020444716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1381 domain-containing protein"
                     /protein_id="HDU2816802.1"
                     /translation="MTQYLVTTFKDSTGRKHTHITRAKSNQRFIVVEAESKEEAKEKY
                     ESQNTPIVYYTNNSKVTLFERPSEEVLGSLFEKK"
     gene            7896..8132
                     /locus_tag="RFE25_001746"
     CDS             7896..8132
                     /locus_tag="RFE25_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816803.1"
                     /translation="MFNTPKMKFPKKYTEIIKKYKNKTPEEKAKIEDDFIKEINDKDS
                     EFYSPMMANMNEHELRAMLRMMPSLIDTGDGNDD"
     gene            8125..8298
                     /locus_tag="RFE25_001747"
     CDS             8125..8298
                     /locus_tag="RFE25_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator RinB"
                     /protein_id="HDU2816804.1"
                     /translation="MIKKILRLIFLLAMYELGKYVTEQVYIMMTANDDVEEPSDFAKF
                     SDQSDLMRAEVSE"
     gene            8299..8445
                     /locus_tag="RFE25_001748"
     CDS             8299..8445
                     /locus_tag="RFE25_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816805.1"
                     /translation="MMWFIIAIILLVILLFGVMLQAEQLKGDVKVKEREIEILRSRLR
                     HFED"
     gene            8469..8891
                     /locus_tag="RFE25_001749"
     CDS             8469..8891
                     /locus_tag="RFE25_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RinA family phage transcriptional activator"
                     /protein_id="HDU2816806.1"
                     /translation="MTKKKYGLKLSTVRKLEDELCDYPNYHKQLEDLRSEIMTPWIPT
                     DTNIGGEFVPSNTSKTEMAVTNYLCSIRRGKILEFKSAIERIINTSSRKEREFIQEYY
                     FNKKTLIAVCYDIHISESTAHRIKKKIVSKLAEELGEY"
     gene            9220..9714
                     /locus_tag="RFE25_001750"
     CDS             9220..9714
                     /locus_tag="RFE25_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDU2816807.1"
                     /translation="MIKLTPKQEKFVLGLIEGKSQRKAYIDAGYSTKGKSDNYIDSRA
                     FELSKNSAILDRYEELRQEAAEQSKWTRQKAFEEYEWLKNVAKNDIEIEGVKKATADA
                     FLASLDGMNRMTLGNEVLTNKKIETEIKMLEKKIDQMDKSENNSQEAEVAKALIKLAG
                     VNND"
     gene            9707..10915
                     /locus_tag="RFE25_001751"
     CDS             9707..10915
                     /locus_tag="RFE25_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HDU2816808.1"
                     /translation="MINEMLNPKQQEVWNCFINDKPKVLIASGAKRAGKTYVFILLFL
                     MHIATYKDKGLNFIIGGATQASIRRNILDDMELILGRELTLDKSNAVKIFGNKVYVFD
                     GQNSDAWKKARGFTSAGAFLNEGTALHNMFIKEVFSRCSYKGARILIDTNPENPMHPV
                     KKDYIDKSGQRLSNGRLNIKAFQFTLFDNTFLDEEYIESIIASTPTGMFTDRDIYGKW
                     VSAEGVVYKDFKEKVHYITEEEFKTKQIKRKYAGVDWGYEHYGSIMVVAEDFDGNKYV
                     IEEHAHRHKEIDDWVAIAKGVIKRHGDILFYCDTARPEHIERFRREKIKARYADKAVI
                     AGIEVISRLFKLNKIFIIKEKVSLFKEEIYNYVWKDNADEPVKLNDDTLDALRYAVYT
                     ANKPSGTGFN"
     gene            10869..12347
                     /locus_tag="RFE25_001752"
     CDS             10869..12347
                     /locus_tag="RFE25_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDU2816809.1"
                     /translation="MQFIQLISQVAQALIKGGNILYPSQPTQTEIFDAIVRTNNKPET
                     LEEMIVRYIKQHLEKLPEISIGQEYYEQRPDIVKEPKPVDATGAVDPLKPDDRMITNF
                     HANLVDQKVSYIVGKPIAFKHTDDEVVKRIDEVLGNRFDDKLHSVLTGASNKGIEWLH
                     PYLDEEGEFKLFRVPAEQGIPIWTDKEHEELEAFIRMYKLENETKVEYWDKVTVNYYV
                     YENGSLIPDYSNNLENSKTHFSTGSWGKIPFIPFKNNDLEISDIFMYKTLIDAYNRRL
                     SDLSNTFKDSNELTYVLKNYDDQELPEFKRLLRYYGAIKVSDNGGVDTIQVEVPVENS
                     KKYLDELYRKIMLFGQAVDFSSDKFGSAPSGVALEFLYTNLNLKADKLARKAKVAIQE
                     LLWFVFEHFDIKGEHNDVDISFNYNKVANTELQVQTAQQSMGIVSHETVLENHPFVED
                     LPAELERIEQEQMEYNKQLPNLDDGGADSAQQQERSNNKESE"
     gene            12286..13266
                     /locus_tag="RFE25_001753"
     CDS             12286..13266
                     /locus_tag="RFE25_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001795666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HDU2816810.1"
                     /translation="MTEVLTVPNNKKDLTIKNQNDIDEYIDNLISKAEKPIEQLFANR
                     LKEIKQIIADMFEKYQSDDVYVTWTEFNKYNRLNKELTRIGTMLTDDYRQVAKMIQKS
                     QEDAYIEKFLMSLYLYETASQTSMQFDFPSKEVITSAIEQPIEFIRLVPTLQKHRDEV
                     LKKIRLHITQGIMSGEGYSKIAKAIRDDIGMSKAQSLRVARTEAGRAMSQAGLDSALV
                     AQKNGLQMYKYWQATKDTRTRDTHRHLDGAKKRIDEPFKSSGCVGQAPKLFVGVNSAK
                     ENINCRCKLMYYIDEDDLPSTTRARKDDGTTEVIPQMTYREWEKYKRKRK"
     gene            13364..13888
                     /locus_tag="RFE25_001754"
     CDS             13364..13888
                     /locus_tag="RFE25_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HDU2816811.1"
                     /translation="MDLYTLLGQFKDGEIDKQKVIDAIDESKSGMVPRSRLNDKNTEI
                     EELKEEISKRDEQIVELKDSVKDESELQKALEEEQNKNAELETKYKDLQLNSAVKLAV
                     NHEANDADDILTFINKDELELADDGTVKGLDEAIGTLKESKPYLFAPSKPTGNTPQDG
                     DPPSPHEAWTEFLN"
     gene            13900..14859
                     /locus_tag="RFE25_001755"
     CDS             13900..14859
                     /locus_tag="RFE25_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HDU2816812.1"
                     /translation="MNKTIKNATGMLKLNLQHFANKSVEPGQTLLKNKHVGILERVTA
                     VNAYSTPALISNDAIFMEGRSFTVMKGDTTELKDYKRNATNEFDHPKIEETTYFLDQE
                     KYWGRFVDALDRKDTEGNIDINYVVARQGAEVVAPYLDNLRFATLARNKAKHLTVGTG
                     SDAQYDAVLDVSVELDEIKAPENRVLFVSPTFYKGIKKFVIALPQGDTRQQVLGKGVQ
                     GELDGFVIVKVPTKLLQGLQAIAVVGEVLASPIQADLAKTNSNIPGMFGTLAEQLLYT
                     GAFVPEHLQKYIFTIGGTEVATKRDGVDAHADNVAKPSGSLEM"
     gene            14876..15202
                     /locus_tag="RFE25_001756"
     CDS             14876..15202
                     /locus_tag="RFE25_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HDU2816813.1"
                     /translation="MYKVVEYFEDAQDNRHPYHEGDIYPRDGLEVSEERLAELSTTNN
                     CREIIGIKLVEDEQTEQSETNADEQKSLSDMKVTELKELAKKRGIKGYSDMKKDELIK
                     VIVGVK"
     gene            15202..15516
                     /locus_tag="RFE25_001757"
     CDS             15202..15516
                     /locus_tag="RFE25_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015978403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HDU2816814.1"
                     /translation="MDTKDVKMINGLSLNDSSNDEQIEYLIEEYKSVAEDYCNQKFDD
                     KAVPSGVKKFIAECIKFGTTGNISARTMGTVSYTYITDIPSSAYAYLMPYRKLSWGKR
                     YV"
     gene            15509..15844
                     /locus_tag="RFE25_001758"
     CDS             15509..15844
                     /locus_tag="RFE25_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000482988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDU2816815.1"
                     /translation="MFNPFNEFPHAIEIGEIEVVGTYPKEYERFKSNETIKGFMDTPT
                     SSETLKFHQMSKDFDRNLYTPYHIPITNKTLFNYEGKTYKVVGEPVDQGGQHEINLTR
                     LRVRPIGKG"
     gene            15831..16121
                     /locus_tag="RFE25_001759"
     CDS             15831..16121
                     /locus_tag="RFE25_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002469447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDU2816816.1"
                     /translation="MAKVKYGNWDLVKELENYERDMERWVKRGIAKTTAKIHNTIISL
                     MPVDTGYLRESVTMDFKDGGFTGVINIGSEYAIYVNYGTGVVCMSHLSVMVS"
     gene            16214..16897
                     /locus_tag="RFE25_001760"
     CDS             16214..16897
                     /locus_tag="RFE25_001760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816817.1"
                     /translation="MLTNSKGEVFEGNFRDLTGKKFNMLKVIEPVRIHNPPKGDRYLY
                     WLVECDCGNTAVKSAKSITTGYSKSCGCLQKIATSKAKKTHGDTDSRLYYIWENMKKR
                     CYKPNSDRYKNYGARGITICEEWKNSYKNFYDWAYNNGYNERLTIERKDINGNYEPSN
                     CTWITRNEQAKNRTSNKWVFLDGIKYSPQELEKIYKISVNTIYARIARGDKGYAVVRP
                     LGQRQFWKR"
     gene            17089..17247
                     /locus_tag="RFE25_001761"
                     /pseudo
     CDS             17089..17247
                     /locus_tag="RFE25_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002480803.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
     gene            17260..17685
                     /locus_tag="RFE25_001762"
     CDS             17260..17685
                     /locus_tag="RFE25_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3168 domain-containing protein"
                     /protein_id="HDU2816818.1"
                     /translation="MWVSVEPELTNQIYKRLISDPNINKIVGDRVFDVVQDDAVYPYI
                     VVGESNVTNNESSATMRETVGIVIHVYSQFATQYEAKLILSAIGYVLNRTIEIENYEF
                     QYSRIDSQAVFPDIDRFTKHGTIRLLFKYRHKKKNEGVY"
     gene            17686..18243
                     /locus_tag="RFE25_001763"
     CDS             17686..18243
                     /locus_tag="RFE25_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDU2816819.1"
                     /translation="MAQKNYLAVVRPAETDLDPVESLLLADLQEGGHTIENDLAEIVR
                     GGKTDYSPNAMSESFKLTIGNVPGDKGIEAVKHAVQTGGQLRIWLYERNKRADGKHHG
                     MFGYVVPESFEMSFDDESDKIELSLKVKWNTAEGAEDNLPKEWFEAAGAPTVEYEKFG
                     EKVGTFENQKKASVVSDSHTEDHSM"
     gene            18310..18816
                     /locus_tag="RFE25_001764"
     CDS             18310..18816
                     /locus_tag="RFE25_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816820.1"
                     /translation="MTEFNPITTLKINDGEKDYEVEAKVTFAFDRKAEKFSEDSEDGR
                     KGAMPGFNVIFNGLLESRNKAILQFWECATAYLKNPPTREQLEKAIDDFITENEDTLP
                     LLQGALDKLNNSGFFKRESRSYWMTLNKAPNMAKSEDKEMTKAGIEMMKENYKEIMGA
                     EPYTITQK"
     gene            18861..19145
                     /locus_tag="RFE25_001765"
     CDS             18861..19145
                     /locus_tag="RFE25_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816821.1"
                     /translation="MLALTPAEWRDWLIGGQDRYLDQRQLLIEQAQANGLVQASKRLT
                     SMIRDIEKQRYEIREPGSYARVQKARLEEEKRRRELFKEGTRKFLESKGG"
     gene            19149..22034
                     /locus_tag="RFE25_001766"
     CDS             19149..22034
                     /locus_tag="RFE25_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDU2816822.1"
                     /translation="MDTHFMAKIMANIRDFQSNVRKAQRLAKTAVPNEIETDVKADIS
                     RFQRALQRAKAMAQKWREHNVKIDGNNSPLKRAIASAKTMLATLHNKTIKVNFDTRGM
                     TKTQILTKALNQSLTDYSEKMDALATKIRTFGTIFAQQVKGLMIASIQALIPVIAGLV
                     PAIMAVLNAVGVLGGGVLGLVGAFSVAGLGVVGFGAMAISALKMVEDGTLAVTKEVQN
                     FRDASDQLKTTWRDIVKENQASIFNAMSAGIRGVTSAMSQLKPFLSEVSMLVEANARK
                     FEDWVKHSETAKKAFEALNSIGGAIFGDLLNAAGRFGDGLVNIFTQLMPLFKFVSQGL
                     QNMSIAFQNWANSVSGQNAIKAFIDYTTTNLPKIGQIFGNVFAGIGNLMIAFAQNSSN
                     IFDWLVKLTSQFRAWSEQVGQSQGFKDFISYVQENGPTIMQLIGNIVKALVAFGTAMA
                     PIASKLLDFITNLAGFIAKLFETHPAIAQVAGVMGILGGVFWALMAPIVAISSVLTNV
                     FGLSLFSVTEKILDFVRTSSLVTGATEALIGAFGSISAPILAVVAVIGAFIGVLVYLW
                     KTNENFRNTITEAWNGVKTAVSGAIQGVVGWLTELWGKIQSTLQPIMPILQVLGQIFM
                     QVLGVLVIGIITNVMNIIQGLWTLITIAFQAIGTVISVAVQIIVGLFTALIQLLTGDF
                     SGAWETIKTTVTNVLDTIWQYMQSVWESIIGFLTGVMNRTLSMFGTSWSQIWSTITNF
                     VSSIWNTVTSWFSRVASSVAEKMGQALNFIITKGSEWVSNIWNTVTSFASKVADGFKR
                     VVSNVGDGMSDALGKIKSFFSDFLNAGAELIGKVAEGVANAAHKVVSAVGDAISSAWD
                     SVTSFVSGHGGGSGLGKGLAVSQAKVMATDFGSAFNKELSSTLTDSIVDPVSTSIDRH
                     MTSDVQHSLKENNRPIVNVTIRNEGDLDLIKSRIDDMNAIDGSFNLL"
     gene            22049..22990
                     /locus_tag="RFE25_001767"
     CDS             22049..22990
                     /locus_tag="RFE25_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001604155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HDU2816823.1"
                     /translation="MIAHDIEVIRNGSQYRVSDNPFTYNHLEVVEYNVTGAGYHRNYS
                     DIEGIDGRFHNYAKEELKKVELKLRYKVPKIAYASHLKSDVQALFAGRFYLRELATPD
                     NSIKYEHILDIPKDKQAFELDYVDGRQLFVGLVSEVSFNTTQISGEFSLSFETTELPY
                     FESVGFSTDLESDNDPEKWSVPDRLPTNEGDKRRQMTFYNTNSGEVYYNGDVPLTQFN
                     QFNVVEIELAEDVKANDKDGFTFYTDKGNISVIKEVDLKAGDKIIFDGKHTYRGYLNI
                     DSFNKTLEQPVLYPGWNRFKSNKVMKQITFRHKLYFR"
     gene            23001..24887
                     /locus_tag="RFE25_001768"
     CDS             23001..24887
                     /locus_tag="RFE25_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDU2816824.1"
                     /translation="MPILLKSLQGVGHAINVSTKVSKKLNEDSSLDLTIIENASTFDA
                     IGAITKMWTITHVEGEDDFNEYVIVILDKSTIGEKIRLDIKARQKELDDLNNSRIYQE
                     YNESFTGVEFFNTVFKGTGYKYVLHPKVDASKFEGLGKGDTRLEIFKKGLERYHLEYE
                     YDAKTKTFHLYDELSKFANYYIKAGVNADNVKIQEDASKCYTFIKGYGDFDGQQTFAE
                     AGLQIEFTHPLAQLIGKREAPPLVDGRIKKEDSLKKAMELVIKKSVTASISLDFVALR
                     EHFPEANPKIGDVVRVVDSAIGYNDLVRIVEITTHRDAYNNITKQDVVLGDFTRRNRY
                     NKAVHDAANYVKSVKSTKSDPSKELKALNAKVNASLSINNELVKQNEKINAKVDKMNT
                     KTVTTANGTIMYDFTSQSSIRNIKSIGTIGDSVARGSHAKTNFTEMLGKKLKAKTTNL
                     ARGGATMATVPIGKEAVENSIYRQAEQIRGDLIILQGTDDDWLHGYWSGVPIGTDKTD
                     TKTFYGAFCSAIEVIRKNNPDSKILVMTATRQCPMSGTTIRRKDTDKNKLGLTLEDYV
                     NAQILACSELDVPVFDAYHTDYFKPYNPAFRKASMEDGLHPNEKGHEVIMYELIKDYY
                     SFYD"
     gene            24900..>25783
                     /locus_tag="RFE25_001769"
     CDS             24900..>25783
                     /locus_tag="RFE25_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816825.1"
                     /translation="MAYGLITSLHSMTGRKIVAQHEYNYRLLDEGMSKLEKMFIYHQK
                     EEIYAHSAKQIKYLNDSVEDYLTYLNGRFSNMILGHNGDGINEVKDARIDNTGYGHKT
                     LQDRLYHDYSTLDAFTKKVEKAVDEHYKEYRATEYRFEPKEQEPEFITDLSPYTNAVM
                     QSFWVDPRTKIIYMTQARPGNHYMLSRLKPNGQFIDRLLVKNGGHGTHNAYRYIDGEL
                     WIYSAVLDSNKNNKFVRFQYRTGEITYGNEMQDVMPNIFNDRYTSAIYNPIENLMIFR
                     REYKASERQAKNSLNFIEV"
BASE COUNT         9541 a         3872 c         5422 g         6948 t
ORIGIN      
        1 gttcaattct tagaaccgaa gaataacaac caacaaccaa acaacaatta tcatcaacaa
       61 agacaaactc aaactggtaa taatcctttt gataacaacg cagactctat agaggatctt
      121 cctttttagg aggcgttaga tgaacgaatt atggaaagat gttgtaggtt acgagggcat
      181 atacgaagta agcagtaaag gtagagttag aactcacaaa aataaagtta cttggtctaa
      241 ccgttatcaa aaatggaggc attggaaaca gcgttattta aaagataaaa cacctaatgg
      301 tcgagatgta agagtaaccc tttggaaaaa tggtaaacgc aaagattttt tagtccacag
      361 attagtggca ttcgccttta taccaatgat agaaggtaaa aattgtatta accatattga
      421 cgggaacccc aaaaataaca atgtagaaaa tcttgaatgg tgtaatcact tggaaaataa
      481 taggcatgca tttgaaacag gattaatgca taccaatatg gctgtaaaac ttattaatca
      541 tttaggtatc gaatatgaat ttataagtat gagtagagca ggaaaattct taggcagaag
      601 tcatagttat attagcgaca aaataaaaaa taatcacaaa gatgttactg atatacatgg
      661 taataaatat aaatttgaga agttgatata aatgccgaaa attactagtt atatcactca
      721 agatgacggt acaacaacag ttgtcatctc gggtgttgaa ttaggcaata aagaaacatt
      781 actacttgat aacgggtttg atgtagaagt agatgtaaac gttatagatc cgtttcaaat
      841 taccggcaag caacgtcgaa aaatattcgc gcttgtcaaa gacatagaag aacatacagg
      901 tcaaccaatg gactatatga gacatatgtt catcgagttt gtaagaacgt actacggcta
      961 tgatgaacgt atttcgctaa gtaattgtac gagaacacaa gcaagtcaaa tcattgaagc
     1021 aacgcttgac tggacgttct acaatgacat accacttagc tacaaaacga gtaatctact
     1081 gaaacaagat aaatcattct tatactggtc aactgttaac cgcaactgtg taatatgcgg
     1141 aaagcctcac gctgacctag cgcattacga agcagtaggt agaggcatga acagaaacaa
     1201 gatgaatcac tacgacaaac atgtattagc gttatgtcgc gaacatcaca acgagcaaca
     1261 tgcgattggt gttaagtcat ttgatgataa atatcaattg catgactcgt ggataaaagt
     1321 tgatgagagg ctcaataaaa tgttgaaagg agagaaaaat gaataagtta ctaatagatg
     1381 actatccgat acaagtatta ccgaaattag ctgaattaat agggttaaac gaagcaatag
     1441 tattgcaaca aattcattat tggctaaaca actcaaaaca taaatacgat ggcaaaactt
     1501 ggatttttaa ttcttatcca gaatggcaaa aacaatttcc attttggagc gagagaacta
     1561 taaaaaggac atttgggagt ttagaaaaac aaaatttatt gcatgtaggt aactacaaca
     1621 aggctggatt tgaccgtaca aaatggtatt caatcaatta tgaaacatta aacaaactag
     1681 tggcacgacc atcgggacaa aatggcccga cgatgaggac aaattggcac gatgcaagag
     1741 gacaaaatga cccgaccaat accatagact acacagagac taacaaacat agagagacag
     1801 acgacgtctc aaagtcattt aagtatatta gtaccaattt agaaattata caaaaccctt
     1861 taaaagcaga acagttagaa cacgaaatta aatcatttaa gcaagatcag ttcgaaatag
     1921 taaaagtcgc taccgattac tgcaaagaaa acaacaaagg tctgaattac ttactaactg
     1981 tattaaagaa ctggaataaa gaaggcgttt cagataaaga aagtgctgaa aacaaattga
     2041 aacctcgtaa ctctaaaaaa gaaactactg atgatgtcat agcacaaatg gaaaaagaat
     2101 tgagtgatga ctaatgccga tgagcaaaac acaagcatta gaaattatta aaaaagttag
     2161 gtacgtatac aacatcgatt ttgataaacc aaagttagaa atgtggattg atgtattaag
     2221 tcaaaacggg gattatcaac caactgtaaa agctgtagat ggatatatca acagtaacaa
     2281 cccgtacccg cctaacctac cagcaatcat gcgtaaggca cctaaaaaag tatctattga
     2341 gccggtagac aacgaaaccg ctacacacca atggaaaatg cagaatgacc ccgaatatgt
     2401 cagacaaaga aaaatagcgc tagataactt catgaataag ttggcagaat ttgggggcga
     2461 taacgaatga attacggtca atttgaaatt gaaagcacaa taatcgctac gctacttaaa
     2521 caaccggacg tactagaaaa gataagagtt aaagattaca tgtttacgaa cgaaaagttt
     2581 aaaacctttt tcaattatgt aatggacgtc ggaaagatag atcatcaaga aatctattta
     2641 aaagcaacta aagataaaga gtttttagat gcagatacta taactaaact ttacaactcc
     2701 gatttcattg gatacggatt ctttgaacgt tatcaacaag aattattgga aagttatcaa
     2761 atcaacaaag cgaaagaatt ggtaactgag ttcaaacaac aacctacgaa ccaaaatttt
     2821 aataacttga ttgatgaact caaggattta aaaacaatta ctaacagaaa agaagacgga
     2881 accaagaagt ttgttgagga gtttgtcgat gagttataca gcgatagccc taagaagcaa
     2941 attaagacgg gttataagct catggattac aaaatagggg gatttgagcc gtcgcaatta
     3001 atcgtcatcg cagcgcgtcc ctcagtgggt aagacaggtt ttgcattaaa catgatgctg
     3061 aacatagcac aaaatggata taaaacatct ttctttagtc tcgaaacaac tggcacatca
     3121 gtattgaaac gtatgttatc aacaattact ggtattgagt taaccaagat aaaagaaatc
     3181 aggaacttaa cgccggatga cttaacaaag ttaacgaatg cgatggataa aatcatgaaa
     3241 ttaggcatcg atatttctga taaaagtaat atcacaccgc aagatgtgcg agcgcaagca
     3301 atgaggcatt cagacaggca acaagttatt tttatagatt atcttcaact gatggatact
     3361 gatgcgaaag ttgatagacg tgtagcagta gaaaagatat cacgtgactt aaagataatc
     3421 gctaacgaga caggcgcaat catcgtacta ctttcacaac tgaatcgtgg tgtcgagtct
     3481 agacaggata aaagaccaat gctatcggac atgaaagaat caggcggaat agaagcagat
     3541 gcgagtttag cgatgctact ttaccgtgat gattattata accgtgacga agatgacagt
     3601 atcactggca aatctattgt tgaatgtaac atagccaaaa acaaagacgg cgaaaccgga
     3661 ataattgaat ttgagtatta caagaagact cagaggtttt tcacatgaat ataatgcaat
     3721 tcaaaagctt attgaaatcg atgtatgaag agacaaagca aagcgacccg attgtagcaa
     3781 atgtatatat cgagactggt tgggcggtca atagattgtt ggacaataac gagttatcgc
     3841 ctttcgatga ttacgacaga gttgaaaaga aaatcatgaa tgaaatcaac tggaagaaaa
     3901 cacacattaa ggagtgttaa aaaatgccga aagaaaaata ttacttatac cgagaagatg
     3961 gcacggaaga tattaaggtc atcaagtata aagacaacgt aaatgaagtt tattcgctca
     4021 caggagccca tttcagcgac gaaaagaaaa ttatgactga tagtgaccta aaacgattta
     4081 aaggcgctca cgggcttcta tatgagcaag aattaggttt acaagcaacg atatttgata
     4141 tttagaggtg gcacatggaa gtacattaca gtagtaaaac aaacgagtgg acaacaccac
     4201 aacatttatt tgatgaccta aacgaagaat tcagttttac attagatcct tgttcaacag
     4261 acgagaacgc caaatgccgg aagtattata cagtaaaaga taatgggtta attcaagact
     4321 ggtctgagga cattgttttt atgaacccgc catacggtcg aagtattaag cgttgggtca
     4381 agaaggctta tgaagaaagt ttgaaaggcg caacggtagt ttgtttaata cccgcaagaa
     4441 cagacacgac atattggcat gattacattt ttaataaggc tgatgatata agattcctac
     4501 gcggtcgtct gaagtttgga gatagtaaaa acagcgctcc ttttcctagc gcaattatcg
     4561 tttatagagg tgcacaatga gtaaatacaa cgctaagaaa gttgagtaca aaggaattgt
     4621 atttgatagc aaagttgagt gtgaatatta ccaatattta gaaagtaata tgaatggcgc
     4681 taactatgat cgtatcgaac tacaacctaa attcgaacta caacctaaat ttgggaagca
     4741 aagaccgatt acgtatatag ccgatttctc tttgtggaag gaagggaaac tggttgaagt
     4801 tatagacgtt aaaggtaagg cgactgaagt tgccaacatc aaagcgaaga tattcagata
     4861 tcagtataga gatgtgaatt taacgtggat atgtaaagcg cctaaataca caggtcaaga
     4921 atggatggta tatgaggact tagtgaaagt cagacgtaaa agaaaaagag aaatgaagtg
     4981 atttaatgca acaacaagca tatataaacg caacgattga tataagaata cctacagaag
     5041 ttgattatca gcattttgat gatgtggatg atgaaaaaga tatgctagca aagcgcttag
     5101 atgacaatcc ggatgaatta ctaaagtatg acaacataac aataagacat gcatatatag
     5161 aggtggaata aatgagtgtc gtgaagatta acggtaaacc atataaattt accgagtcac
     5221 ttataaccaa atgttcaaga aatggagtga agcataatga gcataatcag taacagaaaa
     5281 gtagatatga atgaaacgca agacaatgtt aagcaaccag cacattacac atacggcgat
     5341 attgaaatta tagattttat tgaacaagta acggcacagt atccaccaca attagcattt
     5401 gcaataggta atgcaatcaa atacttgtct agagcaccgt taaagaatgg tcatgaggat
     5461 atggcaaaag cgaagtttta tgtagataga gtgtttgact tgtgggagta atgaccatga
     5521 cagataacgc gcgtaaagaa tacttaaacc aatttttcgg ctctaagaga tatctgtatc
     5581 aggataacga gcgagtggca catatccatg tagtgaatgg cgcttattac tttcacgggc
     5641 atatcgtacc agattggcaa ggtgtgaaaa agacatttga tacagcggaa gagctcggaa
     5701 tatatataaa gcaacatggt ttggaatacg aggaacagaa gcaactaact ttattttaag
     5761 gagatgtaaa aatgaaaatc aaagttaaaa aagaaatgag actagatgaa ttaattaagt
     5821 gggcgcgaga aaatccggag ctatcaaaag gaaaaatttt tcttgcaaaa agttttagta
     5881 atggattcgt tcgttttcaa cgaaatacaa atacgtgttc gatatcaagt tttattccaa
     5941 ttgatactcc tttcatagtt gaagttgaag aggaaatcac agaagataca gtatttgata
     6001 ggttgtttga agtgtacgag cttcaagagg gagcctgtat gtcagcgtta cacacaagta
     6061 ttagtatcaa cgaacgttta gagaacacgt ttttccctac caaagcattc tacatcttga
     6121 acgacggcct aactatgaca ttaatttgga aagatgggag attggtagaa tgatgttgaa
     6181 atttaaagct tgggataaag ataaaaaagt tatgagtatt attgacgaaa tcgattttaa
     6241 tagtgggtac attttgattt caacaggtta taaaagtttc aatgaagtaa aactattaca
     6301 atacacagga tttaaagatg tgcacggtgt ggagatttat gaaggggata ttgttcaaga
     6361 ttgttattcg agagaagtaa gttttatcga gtttaaagaa ggagcctttt atataacttt
     6421 tagcaatgta actgaattac taagtgaaaa tgacgatatt attgaaattg ttggaaatat
     6481 ttttgaaaat gagatgctat tggaggttat gagatgacgt tcaccttatc agatgaacaa
     6541 tataaaaatc tttgtactaa ctctaacaag ttattagata aacttcacaa agcattaaaa
     6601 gattgtgaag agtacaagaa gcaacgatat gagcttattg gggttatagc gaagttacga
     6661 gattgtaaca aagaactgga gaagaaagca agcgcatggg ataggtattg caagagcgtt
     6721 gaaaaagatt taataaacaa attcggtaac gatgatgaaa gagttaaatt cgtaatggaa
     6781 ttaaacaata aaatttttat ggaggatgac acaaatgaat aatcgcgaaa aaatcgaaca
     6841 gtccgttatt agtgctagtg cgtataacgg taatgacaca gaggggttgc taaaagagat
     6901 tgaggacgtg tataagaaag cgcaagcgtt tgatgaaata cttgagggaa tgacaaatgc
     6961 tattcaacat tcagttaaag aaggtattga acttgatgaa gcagtaggga ttatggcagg
     7021 tcaagttgtc tataaatatg aggaggaata ggaaaatgac taacacatta caagtaaaac
     7081 tattatcaaa aaatgctaga atgcccgaac gaaatcataa gacggatgca ggttatgaca
     7141 tattctcagc tgaaactgtc gtactcgaac cacaagaaaa agcagtgatc aaaacagatg
     7201 tagctgtgag tataccagag ggctatgtcg gactattaac tagtcgtagt ggtgtaagta
     7261 gtaaaacgta tttagtgatt gaaacaggca agatagacgc gggatatcat ggcaatttag
     7321 ggattaatat caagaatgat gaagaacgtg atggaatacc ctttttatat gatgatatag
     7381 acgctgaatt agaagatgga ttaataagca ttttagatat aaaaggtaac tatgtacaag
     7441 atggaagagg cataagaaga gtttaccaaa tcaacaaagg cgataaacta gctcaattgg
     7501 ttatcgtgcc tatatggaca ccggaactaa agcaagtgga ggaattcgaa agtgtttcag
     7561 aacgtggagc aaaaggcttc ggaagtagcg gagtgtaaag acatcttaga tcgagttaag
     7621 gaggttttgg ggaagtgaca caatacttag tcacgacatt caaagattca acaggacgca
     7681 agcatacaca cataactcga gctaagagca atcaaaggtt tatagttgtt gaggcagaga
     7741 gtaaagaaga agcgaaagag aaatatgagt cacaaaatac acctattgtt tactacacta
     7801 ataattctaa agtgacctta ttcgaaagac ctagtgaaga agtattaggt tctttgttcg
     7861 aaaagaaata aaatcattaa agaggggaga taataatgtt taatacacct aaaatgaaat
     7921 tcccgaaaaa gtacactgaa ataatcaaaa aatataaaaa taaaacacct gaagaaaaag
     7981 ctaagattga agatgatttc attaaagaaa ttaatgataa agacagtgaa ttttacagtc
     8041 ctatgatggc taatatgaat gaacatgaat taagggctat gttaagaatg atgcctagtt
     8101 taattgatac tggagatgga aatgatgatt aaaaaaatat taagactaat attcttacta
     8161 gcaatgtatg agctaggtaa gtatgtaacg gagcaagtat atattatgat gacggctaat
     8221 gatgatgtag aggagccgag tgacttcgca aagtttagtg atcagtctga tttgatgagg
     8281 gcggaggtgt cagagtagat gatgtggttc atcatagcaa ttatattact agtcatctta
     8341 ttgtttggtg taatgttgca agctgaacag ttaaaaggcg atgtgaaagt taaagagcga
     8401 gagatagaga tattaagaag tagattgaga cactttgaag attaaacata tttgtacgga
     8461 gggtattcat gactaaaaag aaatacggat taaaattatc aacagttcga aagttagaag
     8521 atgagttgtg tgattatcct aattatcata agcaactcga agatttaaga agtgaaataa
     8581 tgacaccgtg gattccaaca gatacaaata taggcgggga gtttgtaccg tctaatacat
     8641 cgaaaacaga aatggcagta actaattatc tttgtagtat acgaagaggt aaaatccttg
     8701 agtttaagag tgcgattgaa cgtatcatca acacatcaag taggaaagaa cgcgaattca
     8761 ttcaagagta ttattttaac aaaaagactt tgattgcggt atgttatgac atacacattt
     8821 ctgaaagtac agcgcataga attaagaaga agatagtttc taaattagcc gaagaattag
     8881 gggaatacta aaattgacag taaaatgaca gtttttgaca cctaaaacga gatattatga
     8941 tattgtaaga attatcttaa gacgtggggt aatagccaca ttagatgttc tcatcgatgt
     9001 gattgagaag cgacaaacat ataaaagatg atatgttacg ctattaatca cttactacct
     9061 gcctatatgg tgggtagttt aattcttgca atttgagtca taactatttt cctcctttca
     9121 catttattga acgtagctcc tgcacaagat gtaggggcat ttttgtattt aaaataacta
     9181 gagtaattaa cgtaaaggcg tgtgatacag tgaaaacaat tgattaaatt aacaccgaag
     9241 caagaaaaat ttgtgctagg actcatagag ggcaagagcc aacgcaaagc atatattgac
     9301 gcagggtatt cgactaaagg taaaagtgat aattatatag atagccgagc ttttgagttg
     9361 agtaagaata gtgcgatttt agataggtat gaagaattgc gtcaagaagc agctgaacaa
     9421 tcaaaatgga cacgccaaaa ggcttttgaa gaatatgagt ggttaaagaa tgtagctaag
     9481 aatgacattg aaatagaggg agtaaagaaa gcgacagctg atgcattcct cgctagtttg
     9541 gacggcatga atagaatgac gttaggaaat gaagttctga ctaacaaaaa gattgaaact
     9601 gaaatcaaga tgcttgagaa aaaaattgac caaatggata aatcagaaaa taattcacaa
     9661 gaagcagaag ttgctaaagc acttattaag ttagcgggtg ttaataatga ttaatgaaat
     9721 gttaaacccg aaacaacaag aagtctggaa ctgctttata aacgataaac ccaaagtatt
     9781 aatagcgagt ggtgcaaaaa gggcaggtaa aacatatgtg ttcatcctgc tttttttaat
     9841 gcatatagct acttataaag acaaggggct taacttcatt attggaggag caacacaagc
     9901 atctataaga cgtaacatac tagatgatat ggagttaata ctaggtagag agttaacact
     9961 cgacaaatct aacgcagtca aaatattcgg taataaagtg tatgtattcg acggacaaaa
    10021 ctcggatgca tggaaaaaag cgcgtggttt tacttcagca ggtgcttttt taaatgaggg
    10081 aacagcatta cacaatatgt ttattaaaga agtgttctca cgttgtagtt acaaaggcgc
    10141 gagaatatta attgatacaa accccgaaaa cccaatgcat ccagttaaaa aagattacat
    10201 tgataagagt ggtcaacgat tatcgaatgg aagactaaat atcaaagcat ttcaatttac
    10261 tttgttcgac aatacatttt tagatgaaga atatattgaa tcgattatag cgagtacacc
    10321 aacaggaatg ttcacagatc gtgacattta tggtaagtgg gtttctgctg agggtgttgt
    10381 atataaagat ttcaaagaaa aagttcatta catcacagaa gaagaattta aaactaaaca
    10441 aataaaaagg aaatatgcag gcgtcgactg gggatatgag cattatggtt ctattatggt
    10501 tgtagcggaa gacttcgacg gaaacaagta cgttattgaa gaacacgcac acagacataa
    10561 agaaatagat gactgggtag ctattgcaaa aggagttata aaaaggcatg gcgatattct
    10621 tttttattgt gatacagcta gacctgaaca tattgaacga tttagaagag agaagataaa
    10681 agcaagatat gctgacaaag ctgttattgc tggcattgaa gttatttcta ggttattcaa
    10741 gttaaataaa atattcatta tcaaagaaaa agttagtttg tttaaagaag aaatatacaa
    10801 ctacgtttgg aaagataatg cagacgaacc agttaaatta aacgatgaca cattagatgc
    10861 gttaagatat gcagtttata cagctaataa gccaagtggc acaggcttta attaaaggag
    10921 gtaatatttt gtaccctagc caaccaacac aaacagaaat atttgatgct attgtgagga
    10981 ctaacaataa gccagaaaca ctggaagaaa tgattgtcag atatataaaa caacatttgg
    11041 agaagttacc tgaaatctca atcggtcaag aatattatga gcaacgtcct gatattgtta
    11101 aggaacctaa gccagttgat gctacaggag cagttgaccc attgaaacca gatgacagaa
    11161 tgattaccaa cttccatgct aacctagtag atcaaaaagt ttcttatatt gtaggtaagc
    11221 ctatcgcttt taaacataca gatgatgaag tagttaaacg tattgatgaa gttttgggca
    11281 atagattcga tgataagtta cacagtgtac taacaggagc cagcaataaa ggtattgaat
    11341 ggttgcatcc ttaccttgat gaagagggag aatttaagtt atttagagta ccagcagaac
    11401 aaggtattcc tatatggact gataaagagc acgaagaatt agaggcgttt atcaggatgt
    11461 ataaattgga aaatgaaact aaagttgaat actgggacaa agtaacggtt aattactacg
    11521 tttatgaaaa tggctcgctt attccggatt actctaacaa tttggagaat tcaaaaacgc
    11581 attttagtac agggtcgtgg ggtaagattc catttattcc attcaaaaat aacgacttag
    11641 aaatatcaga catatttatg tataaaacat tgattgatgc gtataacagg cgattatctg
    11701 atttatccaa tacttttaaa gattcaaacg aattaacgta tgtattgaag aactacgatg
    11761 accaagagtt accagaattt aaacggttac tacgttatta cggtgcgata aaagtatcag
    11821 ataacggggg tgtcgacaca atacaggtag aagtaccagt tgaaaacagt aagaagtatt
    11881 tagatgagtt atatcgaaaa ataatgttgt ttggtcaagc ggttgacttt agttctgata
    11941 aattcggttc tgctccaagt ggggttgcgt tagagttttt atatactaac ttaaacttga
    12001 aagcggataa gttagcgcgt aaagctaaag ttgctataca ggagttactt tggtttgtgt
    12061 ttgagcactt cgacatcaaa ggagaacata atgatgtcga tattagtttc aactacaaca
    12121 aagtagcgaa cacagaatta caagtacaaa cagctcagca atctatggga attgtaagcc
    12181 atgaaactgt attggaaaat cacccgtttg tcgaagattt accagcagaa ctcgaacgaa
    12241 tagagcaaga acaaatggag tacaacaagc aactccctaa tttagatgac ggaggtgctg
    12301 acagtgccca acaacaagaa agatctaaca ataaagaatc agaatgatat tgatgagtat
    12361 atcgacaatc taatctctaa agctgagaag ccgatagaac aactatttgc taatcgactt
    12421 aaagagataa aacaaatcat cgcagatatg ttcgagaagt atcaaagtga tgatgtgtat
    12481 gttacatgga ctgaattcaa taaatataac aggctcaata aggagttaac tcgtataggt
    12541 acaatgttga ctgatgacta caggcaagta gctaagatga ttcagaagtc acaggaagac
    12601 gcttatatag aaaagttcct tatgagcctt tatttatatg agacggcgag tcaaacatct
    12661 atgcagtttg attttcctag taaagaagtt atcacatcag ctattgaaca acctattgag
    12721 ttcattcgat tagtaccgac gctacagaag catcgtgatg aagtattgaa aaagatacgc
    12781 ttacacatca cacaaggcat tatgagcgga gagggctact ctaaaatagc gaaagcaatc
    12841 cgtgatgata ttggcatgtc taaagctcaa tcgttgcgtg tagctcgtac agaagcgggt
    12901 agagcgatgt cacaagctgg acttgatagt gcattggtag ctcaaaagaa tggcttacag
    12961 atgtataagt attggcaagc caccaaagat acacgtacaa gggacacgca caggcatcta
    13021 gacggtgcta aaaagagaat agatgaaccg ttcaagtcga gcggttgtgt tggacaagca
    13081 cctaagttgt tcgtcggtgt gaatagtgca aaagaaaaca tcaactgtcg ttgtaagctt
    13141 atgtattaca ttgatgaaga tgatttgcct agtacaacaa gagcacgtaa agatgatggc
    13201 acaaccgaag taataccaca aatgacctat cgtgagtggg agaaatataa acgtaaaaga
    13261 aagtagttta ctactcgacc ttagcatgtc gttaaactgc ttctttttat accaaaattc
    13321 ttcgtggcgt tgcacgtaaa actcgtaaaa aggagtagtt taaatggatt tatacacatt
    13381 gttaggacaa tttaaagacg gagaaatcga caagcaaaag gtaattgatg cgattgacga
    13441 atcaaaatcg ggaatggtac cacgttcaag attgaacgac aagaataccg aaattgaaga
    13501 gttaaaagaa gagatttcta aacgtgatga acaaattgtc gaattgaaag actctgtaaa
    13561 agatgagagc gagcttcaga aagcactcga agaagaacaa aataaaaacg cagagttaga
    13621 aacaaagtat aaagatttac aacttaatag cgcagtgaaa ttagcggtta atcatgaagc
    13681 taatgacgct gacgacattc taacattcat caataaagat gaactggaat tagcagacga
    13741 cggcactgta aaaggtttag atgaagcgat tggaacgctt aaagagtcta aaccttattt
    13801 atttgcaccg tctaagccta caggtaacac accgcaagac ggagacccac caagcccgca
    13861 tgaagcgtgg acagaatttt taaattagga gtgtattaca tgaataaaac aatcaaaaat
    13921 gctactggta tgttgaagtt aaacttacaa cattttgcta acaagtcagt agagcctgga
    13981 caaacgttat tgaaaaataa gcacgttgga attttagaaa gagtcacagc ggttaatgcc
    14041 tattcaacac cggcattaat tagtaatgac gccattttta tggaaggtcg ttctttcaca
    14101 gttatgaaag gagatacaac agagttaaag gattacaaac gtaatgctac taatgaattt
    14161 gaccatccaa aaattgaaga aacaacatac ttcttagatc aagaaaaata ctggggtcgt
    14221 ttcgtagatg ctttagacag aaaagacaca gaaggtaata ttgatattaa ttacgtagtg
    14281 gcacgtcaag gtgcggaagt tgtagcgcca tatttagata atttacgttt cgctacacta
    14341 gcacgtaata aagctaaaca tttaacagtt ggtactggtt cagatgcaca gtatgatgcg
    14401 gttttagatg tatctgttga attagatgaa atcaaagcgc cagaaaaccg tgtgctattc
    14461 gtttctccta cattctacaa aggtattaaa aagtttgtta ttgcattacc tcaaggagat
    14521 acgcgtcaac aagtattagg caaaggtgta caaggcgaat tagacggttt tgttatcgtt
    14581 aaagtaccaa cgaaattatt acaagggtta caagctatcg cagttgtagg cgaagtttta
    14641 gcttctccaa ttcaagctga tttggctaaa acaaattcaa atattcctgg tatgttcgga
    14701 acgttagcag aacaattgct atatactggt gcatttgtac ctgaacactt acaaaagtac
    14761 attttcacta ttggtggtac agaagttgct acaaaacgtg atggtgttga tgcacatgct
    14821 gacaatgtag ctaaaccgtc tggaagctta gaaatgtaat aggaggtagt gacgtatgta
    14881 taaagtagtc gaatattttg aagatgctca agacaacaga cacccttatc acgaagggga
    14941 tatataccca cgtgatgggt tagaagtatc agaagaacga ttagccgaat tatccacaac
    15001 aaataactgc cgtgaaataa ttggtattaa actggttgaa gacgaacaaa cagaacagtc
    15061 tgagacgaac gctgacgagc aaaaaagttt atctgatatg aaagtaacag aattaaaaga
    15121 acttgctaaa aagcgtggaa ttaaaggcta tagcgatatg aaaaaagatg agcttatcaa
    15181 agttatagtg ggtgttaagt aatggacaca aaagacgtca aaatgattaa tggactttca
    15241 ctcaatgatt cgtctaacga tgagcagatc gaatatctta ttgaagaata taaaagtgtt
    15301 gcagaagatt attgtaatca gaagtttgat gacaaagcgg tgccgtcggg tgttaagaag
    15361 tttattgctg aatgtatcaa gtttggtaca actggcaata tctctgcgcg cacgatgggc
    15421 actgtgagtt atacctatat aactgacata cctagtagtg cttatgcata tttaatgcct
    15481 tatcgtaagt taagttgggg taagcgatat gtttaatccg tttaatgagt ttccgcacgc
    15541 aattgaaatt ggagagattg aagtcgtagg aacatatccc aaagaatacg agcgttttaa
    15601 aagtaacgaa acaattaaag gatttatgga cacacctaca tcaagtgaga cactcaaatt
    15661 tcatcaaatg agcaaagact ttgaccgaaa cctatatacg ccgtaccaca taccaataac
    15721 aaacaaaact ttatttaatt acgagggtaa aacgtacaaa gttgtaggcg aaccggtcga
    15781 ccaaggcgga caacatgaaa tcaatttaac tagattgagg gtgcgaccta ttggcaaagg
    15841 ttaagtatgg taattgggac ttagtaaaag agttggaaaa ttacgagcga gacatggagc
    15901 gatgggtcaa acgaggtata gcaaagacaa ctgctaagat tcacaataca atcatttcat
    15961 taatgccagt tgataccggc tatcttaggg aaagtgtaac aatggacttt aaagacggcg
    16021 gtttcactgg tgttattaat attggtagtg aatacgcaat atatgtcaac tacggtacag
    16081 gggtagtgtg tatgtcccac ttatcagtaa tggtaagtta aaaatcgggc aaaatcggtg
    16141 aaagtcttat atgtaaaata tcgactggta tatacgatga aggtttggta taatatccat
    16201 aaggagtgat gttatgctaa ccaattctaa aggcgaagtt tttgaaggta attttagaga
    16261 cttgacaggc aaaaaattca atatgttaaa agtcatagaa ccagtaagga ttcacaatcc
    16321 acctaaagga gatagatacc tgtattggtt agtagagtgt gattgtggaa atactgcagt
    16381 taaatctgca aaatctataa caacaggtta ttccaaaagt tgtggatgct tacaaaagat
    16441 agcgacaagc aaggctaaaa aaactcatgg tgatacagat tctagactgt attatatatg
    16501 ggaaaatatg aagaaacgtt gctataaacc aaattccgat agatacaaaa attatggtgc
    16561 tagaggaata actatctgtg aagaatggaa aaatagttat aaaaatttct atgactgggc
    16621 atataataat ggttacaatg aacgcttaac tattgaaaga aaagatatta acggtaacta
    16681 cgaaccttca aattgtactt ggataacaag gaatgaacaa gctaaaaaca gaactagcaa
    16741 taaatgggta ttcctagatg gtattaagta ctcgccgcaa gaattagaaa aaatatacaa
    16801 aatatcagtt aacacaatat atgcaaggat tgctcgtggt gataaaggtt acgctgttgt
    16861 tagaccttta ggacaaagac aattctggaa aagataacac cgaggtaact taatagattg
    16921 cgaaaggcta ttgagcactg tagagcgtag gaagtgaata aatataatct tcccaagagt
    16981 gtccgacaac caataatggt tgtctttttt attggttgaa aatgtacgcc gaacttacag
    17041 gtgactgtaa gaagtaaagg ataaaaagcc tttacgataa caagatgata cgcagtcggt
    17101 ccaggtggta gtcgtgcaaa gaatatcccg tggcgttaca aagacgcaga cggacattgg
    17161 cacactacta aagggcaaca tgctcaacct ttttgggagc cagcaataga cgctggacga
    17221 gcattcttta ataagtattt ttcatgaggt ggttaagata tgtgggtatc agttgaacct
    17281 gaacttacaa atcaaatata taaaagatta atctcagacc ctaacattaa caaaatagtt
    17341 ggtgataggg tctttgacgt tgttcaagat gacgctgttt acccatatat tgttgtgggt
    17401 gaatcaaacg tcactaacaa cgaatctagt gcaacaatga gagaaacagt tggtattgtc
    17461 atacatgtgt attcacagtt cgctacacaa tacgaggcta agctcatttt aagcgcaata
    17521 ggctatgtgc taaacaggac tatagagata gaaaattacg aattccaata tagccgtatc
    17581 gatagtcaag cagtattccc tgatatagac aggtttacta agcatggcac gatacggctt
    17641 ttatttaagt acagacataa aaagaaaaac gaaggagtgt attaaatggc gcaaaaaaac
    17701 tatttagcag ttgtacgtcc agctgaaact gacttagatc cagtagaatc tttattatta
    17761 gctgacttac aagaaggtgg acatacgatt gaaaatgatt tagctgaaat agtacgaggc
    17821 ggtaaaacgg actattctcc caatgcaatg tcagaatcat ttaaattaac aattggtaat
    17881 gtgcctggag ataaaggaat tgaagcagtg aaacacgctg tacaaacagg tggacagttg
    17941 cgtatatggc tttatgagcg taataaacgt gcagacggta aacatcacgg aatgtttggt
    18001 tatgttgttc cagaatcatt tgaaatgtca tttgatgatg aaagtgacaa aatcgaacta
    18061 tcattaaaag ttaaatggaa tacagcagaa ggtgctgaag ataacttgcc gaaagagtgg
    18121 tttgaagctg caggtgcgcc tacagttgaa tacgaaaaat tcggcgaaaa agtcggaaca
    18181 ttcgagaatc aaaagaaagc tagtgttgta tctgattcac acacggaaga ccattctatg
    18241 taaactaata gatcaagggg gcgtaagctc cctatttttt tataaaaaaa ttgaaaagag
    18301 gtatatattt tgactgaatt taatccaatt acaacattaa aaattaatga cggagaaaaa
    18361 gattacgaag tagaagcaaa agtaacattt gcatttgacc gaaaagctga aaaattctca
    18421 gaagatagcg aagatgggag aaaaggagca atgccaggat tcaatgttat ctttaacggt
    18481 ttgctagaat ctagaaacaa agcgatttta caattttggg aatgtgctac tgcttattta
    18541 aaaaacccac caactcgaga acaattagaa aaagcaattg atgatttcat cactgaaaac
    18601 gaggatactt tgccgttatt acaaggggct ttggacaaac ttaacaatag tggttttttc
    18661 aagagggaga gtcgctcgta ctggatgaca ttgaacaaag caccgaatat ggccaaaagc
    18721 gaggacaaag aaatgacgaa agcaggcata gaaatgatga aagagaatta caaggaaatc
    18781 atgggcgcag aaccttacac gattactcaa aaataaggca actgacagct agatatttag
    18841 gatatatccc tgaacatgaa ttgttagcgc taacacctgc tgaatggcgt gattggctta
    18901 ttggtggtca ggataggtac ctagatcaaa gacaattatt aattgaacaa gcgcaagcta
    18961 acggcttagt acaagcttct aagaggctaa ctagtatgat tcgtgacatt gagaaacaac
    19021 gttacgaaat aagggagcct ggtagctatg ctcgtgtaca aaaagctaga ttagaagaag
    19081 aaaaaagaag acgtgaactc ttcaaagaag gtacaagaaa attccttgaa tcgaaaggag
    19141 gttagccttt ggatactcat tttatggcaa agattatggc caatattaga gattttcaaa
    19201 gcaatgtaag gaaagctcaa cgattagcaa agacggctgt accaaacgaa attgaaacag
    19261 atgtaaaagc agatatttca agattccaaa gagctttaca acgcgctaaa gctatggcgc
    19321 aaaaatggcg tgaacataac gttaaaatag atggtaataa ttcaccgtta aaacgtgcaa
    19381 ttgctagtgc aaaaacgatg ttggccacgt tacacaacaa aacaataaaa gttaatttcg
    19441 atacgagagg tatgacaaaa acccaaattt taactaaggc actgaatcag tccttaactg
    19501 attatagtga gaaaatggac gcgctagcta ctaaaattcg tacatttggt acaatttttg
    19561 cacaacaagt taaaggctta atgattgcta gtatacaagc attgatacca gtgattgccg
    19621 ggttagtacc tgcaataatg gcagtactta atgcggttgg tgtattaggt ggtggcgttt
    19681 taggtttagt tggcgcattc tctgtcgcag gtcttggagt tgttggcttt ggtgcaatgg
    19741 ctattagcgc tcttaaaatg gttgaagatg gaacattggc agtaacaaaa gaagttcaaa
    19801 actttagaga tgcgagcgat cagttaaaaa ctacatggcg tgatattgtt aaagagaatc
    19861 aagcaagtat ctttaatgcg atgtcagcag gtatcagagg cgttacaagt gcgatgtctc
    19921 aattaaaacc attcttatcc gaagtatcta tgctggttga agcaaacgca cgcaagtttg
    19981 aggattgggt taaacattct gaaacagcta agaaagcatt tgaagcgttg aatagcatag
    20041 gtggcgcaat cttcggagat ttattgaacg ctgcaggacg atttggcgac ggattagtta
    20101 acattttcac tcaattaatg ccgttgttca aatttgtgtc tcaaggacta cagaacatgt
    20161 ctatagcttt ccaaaattgg gctaatagtg tatctggtca gaatgctatt aaagcgttta
    20221 ttgactacac taccactaac ttacctaaga ttggtcagat atttggtaat gtgttcgctg
    20281 gtattggtaa tttaatgatt gcttttgcac aaaacagttc caacattttt gattggttgg
    20341 ttaaattaac ttctcaattt agagcatggt cagaacaagt aggacaatca caagggttta
    20401 aagactttat cagttatgtt caagagaatg gtcctactat tatgcagtta atcggtaata
    20461 tcgtaaaagc attagttgct tttggtactg caatggctcc tatagctagt aaattgttag
    20521 actttatcac taatctagct ggatttatcg ctaaactatt cgaaacacac ccagctatag
    20581 cacaagttgc tggcgttatg ggtattttag gcggtgtatt ttgggcttta atggctccga
    20641 ttgttgctat aagtagtgta cttacaaatg tgtttggttt gagcttattc agcgtcactg
    20701 aaaagatttt agacttcgtt agaacatcaa gtttagttac tggagctacg gaagcattaa
    20761 taggtgcatt cggttcgatt tcagcaccta ttttagcagt tgttgcagta attggtgcat
    20821 tcattggtgt cctcgtttat ttatggaaaa caaacgagaa ctttagaaat actattactg
    20881 aagcgtggaa cggtgttaaa acggcagttt ctggtgcgat tcaaggtgta gtcggctggt
    20941 taactgaatt gtggggcaaa atccaatcta ccttacaacc gataatgcct atattgcaag
    21001 tattaggaca aatattcatg caagttttag gtgttttggt aataggcatc attacaaacg
    21061 ttatgaatat catacaaggt ttgtggactt taattacaat tgcgttccaa gccataggaa
    21121 cagtgatatc cgtagcagtc caaatcatag taggtttgtt cactgcttta attcagttgc
    21181 ttactggcga cttctcaggt gcttgggaga ctattaaaac tacggttacc aatgtgcttg
    21241 atacgatttg gcaatacatg caatcagttt gggagtcaat tatcggcttt ttaactggcg
    21301 taatgaatcg aacactttct atgtttggta caagttggtc acagatatgg agtacaatca
    21361 ctaattttgt tagcagtatt tggaacactg ttacaagttg gttcagtcga gtggcttcga
    21421 gtgtagctga aaaaatgggg caagcactaa actttattat cacaaaaggt tctgaatggg
    21481 tttctaacat ttggaataca gttacaagtt tcgcgagtaa agtagctgat gggtttaaaa
    21541 gagttgtctc aaatgtaggt gacggtatga gtgatgcact tggtaagatt aaaagtttct
    21601 tcagtgattt cttaaatgcc ggagcggaat taatcggcaa agtagctgag ggtgtagcca
    21661 atgctgcgca caaagttgtt agtgcagtag gcgatgcaat ttcatctgca tgggactctg
    21721 taacttcatt cgtaagtgga cacggcggag gtagtggctt aggcaaaggt ttagcggtat
    21781 cacaagctaa agtaatggct acagactttg gcagtgcctt taataaagag ctatcctcta
    21841 ctttgacaga tagtatagta gatcctgtaa gtacttctat agacagacac atgactagcg
    21901 atgttcaaca tagcttaaaa gaaaataata gacctattgt gaatgtaacg attagaaatg
    21961 agggcgacct tgatttaatt aaatcacgca tcgatgacat gaacgctata gacggaagtt
    22021 tcaacttatt ataagggagg tttgttagtt gatagcgcac gatatagaag taataaggaa
    22081 tggttcgcag tatcgcgtca gtgacaatcc tttcacttat aatcacttgg aagtagttga
    22141 atataacgtt acaggcgcag gatatcatcg taactattct gatatagagg gtattgatgg
    22201 tagatttcat aattacgcta aagaagaact taaaaaagta gagcttaagc taaggtataa
    22261 agtacctaaa attgcttatg cttcacattt aaagtcagac gtccaagcac tatttgctgg
    22321 acgtttttat ttaagggaat tagctacacc agacaattca attaagtatg agcatatatt
    22381 agatatacca aaagacaaac aagcatttga gcttgattat gttgatggac gacaactttt
    22441 tgtaggacta gtaagtgaag tttcttttaa cacaactcaa atatcagggg aattttcttt
    22501 gtcgtttgaa acaaccgaac taccatactt tgaaagtgtc ggttttagta ctgatcttga
    22561 aagtgataac gaccctgaaa aatggtcggt acctgataga ttgcctacaa acgaaggtga
    22621 taagaggcgt caaatgacat tttacaacac taactcagga gaagtttatt ataacggtga
    22681 tgttccttta acacagttta atcagtttaa tgttgttgaa atagagttag ccgaagatgt
    22741 taaagctaat gataaggatg gattcacttt ctatacagat aaaggaaata tctcagttat
    22801 taaggaagtt gatttaaaag ccggagataa aataatcttc gacggtaaac atacctatag
    22861 aggttattta aatatagatt cttttaataa aactttagaa caaccggttt tatatccagg
    22921 ctggaatcga ttcaagtcta ataaagtaat gaaacaaatt acatttagac acaaattata
    22981 ttttagataa ggagtagcct atgccaattt tattaaaaag tctacagggt gtagggcacg
    23041 ctattaatgt tagtacaaaa gtaagtaaaa agttaaatga agatagttct ttggatctaa
    23101 ctattatcga gaacgcgagt acgtttgacg caataggtgc tataactaaa atgtggacga
    23161 tcactcatgt tgaaggtgaa gatgatttca acgaatatgt aattgtcata cttgataagt
    23221 ctactattgg tgaaaaaata aggcttgata tcaaagctag acaaaaagaa cttgatgacc
    23281 ttaacaattc taggatttac caagagtata acgaaagttt tacaggcgtt gagttcttca
    23341 atactgtctt taaaggaacg ggttataagt atgtattaca tccaaaagta gatgcatcta
    23401 aattcgaggg attaggcaaa ggagatacac gattagaaat ctttaaaaaa ggacttgagc
    23461 gttatcatct cgaatatgaa tacgatgcaa agactaaaac gtttcatttg tatgatgaat
    23521 tatctaagtt tgccaattat tacattaaag ctggtgtgaa tgctgataac gtcaaaatac
    23581 aagaagacgc atctaaatgt tataccttta ttaaaggtta tggtgatttt gatggacaac
    23641 agacttttgc agaagcggga ctacaaattg aattcactca tccattagca caattgatag
    23701 gtaaaagaga agcgccacca cttgttgatg gacgtattaa aaaagaagat agtttaaaaa
    23761 aagcaatgga gctagtgata aagaaaagtg tcactgcttc tatttcctta gactttgtag
    23821 cgttacgtga acacttccca gaagctaacc ctaaaatagg tgatgttgtt agagtggtgg
    23881 attctgccat aggatataac gacttagtga gaatagtcga aatcactaca catagagatg
    23941 cgtacaataa tatcactaag caagatgtag tattaggaga ctttacaagg cgtaatcgat
    24001 acaacaaagc agttcatgat gctgcaaatt atgttaaaag cgtaaaatct acaaaatccg
    24061 acccatctaa agaactaaaa gcattaaacg caaaagttaa cgcaagttta tccataaata
    24121 atgaattggt taagcagaat gaaaaaataa acgctaaagt cgataagatg aatactaaaa
    24181 cagttacaac tgctaatggt acgatcatgt acgactttac tagtcaatca agtataagaa
    24241 acatcaaatc aattggaacg attggcgact ctgtagctag agggtcgcac gcaaaaacta
    24301 atttcacaga aatgttaggc aagaaattga aagctaaaac gactaatctt gcaagaggtg
    24361 gcgcaacaat ggcaacagtt ccaataggta aagaagcggt agaaaacagc atttatagac
    24421 aagcagagca aataagagga gacctaatca tattacaagg tacagatgat gactggttac
    24481 acggttattg gtcaggtgta ccgataggca ctgataaaac ggatacaaaa acgttttacg
    24541 gtgccttttg ttctgcaatt gaagttatta gaaagaataa tccggattca aaaatactag
    24601 tgatgacagc tacaagacaa tgccctatga gtggtacaac aatacgccgt aaagacacgg
    24661 acaaaaacaa actagggtta acacttgagg actatgtaaa cgctcaaata ttagcttgta
    24721 gtgagttaga tgtaccagtg tttgacgcat atcacacaga ttactttaag ccatacaatc
    24781 cagcttttag gaaagcgagc atggaggacg gcttacaccc taacgaaaaa ggtcacgagg
    24841 ttattatgta cgagttaatc aaggattatt acagttttta cgactaaagg aggcaaccaa
    24901 tggcttacgg attaattaca agtttacatt caatgacagg tcggaaaata gttgctcaac
    24961 atgagtataa ctatcgcttg ttagatgaag gtatgagcaa acttgagaaa atgtttatat
    25021 accatcaaaa agaagaaata tacgcacact cagcgaaaca aattaaatac ttgaatgaca
    25081 gtgttgaaga ttatttaacg tatttaaatg gccgttttag caatatgatt ctaggccata
    25141 acggcgacgg tatcaatgaa gtaaaagacg cgcgtattga taatacaggt tatggtcata
    25201 agacattgca agatcgtttg tatcatgatt attcaacact agatgctttc actaaaaagg
    25261 ttgagaaagc tgtagatgaa cactataaag aataccgagc gacagaatac cgattcgaac
    25321 caaaagagca agaaccggaa tttatcactg atttatcgcc atatacaaat gcagtaatgc
    25381 aatcattttg ggtagaccct agaacgaaaa ttatttatat gacgcaagct cgtccaggta
    25441 atcattacat gttatctaga ttgaagccca acggacaatt tattgataga ttgcttgtta
    25501 aaaacggcgg tcacggtaca cacaatgcgt atagatacat tgatggagaa ttatggattt
    25561 attcagctgt attggacagt aacaaaaaca acaagtttgt acgtttccaa tatagaactg
    25621 gagaaataac ttatggtaat gaaatgcaag atgtcatgcc gaatatattt aacgacagat
    25681 atacgtcagc gatttataat cctatagaaa atttaatgat tttcagacgt gaatataaag
    25741 cttctgaaag acaagctaag aattcattga atttcattga agt
//
LOCUS       DAPDIM010000041        24698 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000041 DAPDIM010000000
VERSION     DAPDIM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 24698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24698
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.041"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..108
                     /locus_tag="RFE25_001770"
     CDS             <1..108
                     /locus_tag="RFE25_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816826.1"
                     /translation="LNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE"
     gene            65..289
                     /locus_tag="RFE25_001771"
     CDS             65..289
                     /locus_tag="RFE25_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816827.1"
                     /translation="MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQ
                     DLRNGKTKLEDARFRTIIKLYSYYVSLKEH"
     gene            complement(724..1440)
                     /locus_tag="RFE25_001772"
     CDS             complement(724..1440)
                     /locus_tag="RFE25_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL12"
                     /protein_id="HDU2816828.1"
                     /translation="MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQD
                     ETNINELIKYYTQPHFSFSNKWLYQYDNENIYVELKRYSWSAHISLWGAESWGNINQL
                     KDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAH
                     KIYQGNKPVLTLKEIDFRAREALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHS
                     DLANVYVKNPNKITVDVLFD"
     gene            complement(1548..2273)
                     /locus_tag="RFE25_001773"
     CDS             complement(1548..2273)
                     /locus_tag="RFE25_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL13"
                     /protein_id="HDU2816829.1"
                     /translation="MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQN
                     ETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQL
                     RNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGF
                     PVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPS
                     TDANRYVKKPQNAKIEVILEKSN"
     gene            complement(2368..3093)
                     /locus_tag="RFE25_001774"
     CDS             complement(2368..3093)
                     /locus_tag="RFE25_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL14"
                     /protein_id="HDU2816830.1"
                     /translation="MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISEN
                     ETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQL
                     RNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGH
                     EFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKL
                     TDTNRYVKNPKNAQIEVILEKSN"
     gene            3531..4532
                     /gene="argF"
                     /locus_tag="RFE25_001775"
     CDS             3531..4532
                     /gene="argF"
                     /locus_tag="RFE25_001775"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDU2816831.1"
                     /translation="MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLK
                     NKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYD
                     GIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTY
                     VGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDI
                     DQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPS
                     FHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF"
     gene            4555..5487
                     /gene="arcC"
                     /locus_tag="RFE25_001776"
     CDS             4555..5487
                     /gene="arcC"
                     /locus_tag="RFE25_001776"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDU2816832.1"
                     /translation="MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVIS
                     HGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDK
                     QVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVP
                     SPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLG
                     ANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAA
                     ISFIENNPKGSVLITSLNELDAALEGKVGTVIKK"
     gene            5659..7215
                     /locus_tag="RFE25_001777"
     CDS             5659..7215
                     /locus_tag="RFE25_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDU2816833.1"
                     /translation="MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAY
                     SKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTY
                     ERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKT
                     KGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASS
                     VGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPK
                     ASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVM
                     ASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEG
                     MISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTV
                     GIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGG
                     VLITQVLIYS"
     gene            7522..7749
                     /locus_tag="RFE25_001778"
     CDS             7522..7749
                     /locus_tag="RFE25_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816834.1"
                     /translation="MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENI
                     PHLPIILFILMFIFGVPSEMIKDRQRKNNGV"
     gene            complement(8055..9002)
                     /locus_tag="RFE25_001779"
     CDS             complement(8055..9002)
                     /locus_tag="RFE25_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDU2816835.1"
                     /translation="MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWI
                     HLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIW
                     ILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTV
                     IYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVI
                     IFLILAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKG
                     LLFIEVLLATVIVLRVFIGYLHFFLKKENQDKFLRNASQ"
     gene            9251..9438
                     /locus_tag="RFE25_001780"
                     /pseudo
     CDS             9251..9438
                     /locus_tag="RFE25_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(9906..9979)
                     /locus_tag="RFE25_001781"
     tRNA            complement(9906..9979)
                     /locus_tag="RFE25_001781"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9943..9945),aa:Arg,seq:tct)
     gene            10343..10477
                     /locus_tag="RFE25_001782"
     CDS             10343..10477
                     /locus_tag="RFE25_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class phenol-soluble modulin"
                     /protein_id="HDU2816836.1"
                     /translation="MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
                     "
     gene            10534..10668
                     /locus_tag="RFE25_001783"
     CDS             10534..10668
                     /locus_tag="RFE25_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class phenol-soluble modulin"
                     /protein_id="HDU2816837.1"
                     /translation="MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF
                     "
     gene            10792..11487
                     /locus_tag="RFE25_001784"
     CDS             10792..11487
                     /locus_tag="RFE25_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDU2816838.1"
                     /translation="MGKLGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDF
                     LTFKKINHQHWEAFQQNKLTKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKV
                     KYFDQTLETIVELSKRHDLYIVTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPN
                     PEFFNYVFNDIGEDERQHSIIVGDSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDY
                     EINSWKQLNDIVR"
     gene            complement(11596..12036)
                     /locus_tag="RFE25_001785"
     CDS             complement(11596..12036)
                     /locus_tag="RFE25_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDU2816839.1"
                     /translation="MSEIKRLEINYKTDELFENFRAFGNKDLYMVNELNGQMIDASSD
                     SPFYGIFVGDQLGARMALLKKGDVEEIYFPDFEDYILLWKLEVLPKYQNRGYASELID
                     FAKSFNMPIKAIGRNDSKDFFLHHGFTDVEAKNIEGHDVLLWKP"
     gene            12231..13844
                     /gene="bshC"
                     /locus_tag="RFE25_001786"
     CDS             12231..13844
                     /gene="bshC"
                     /locus_tag="RFE25_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol biosynthesis cysteine-adding enzyme
                     BshC"
                     /protein_id="HDU2816840.1"
                     /translation="MDCKVVSLNEKDQFIPKIKSSDPVITGLFQYDAAQQTSFEKRMS
                     KENNGREAALANVIREYMSDLKLSNEQELNIQHLANGSKVVIGGQQAGLFGGPLYTFH
                     KIFSIITLSKELTDTHKQQVVPVFWIAGEDHDFDEVNHTFVYNENHGSLHKVKYHTME
                     MPETTVSRYYPDKAELKQTLKTMFIHMKETVHTQGLLEICDRIIDQYDSWTDMFKALL
                     HETFKAYGVLFIDAQFEPLRKMEAPMFKKILKKHQLLDDAFRATQQRTQNQGLNAMIQ
                     TDTNVHLFLHDENMRQLVSYDGKHFKLNKTDKTYIKEEIINIAENQPELFSNNVVTRP
                     LMEEWLFNTVAFVGGPSEIKYWAELKDVFELFDVEMPIVMPRLRITYLNDRIEKLLSK
                     YNIPLEKVLVDGVEGERSKFIREQASHQFIEKVEGMIEQQRRLNKDLLDEVAGNQNNI
                     NLVNKNNEIHIQQYDYLLKRYLLNIERENDISMKQFREIQETLHPMGGLQERIWNPLQ
                     ILNDFGTDVFKPSTYPPLSYTFDHIIIKP"
     gene            13988..14419
                     /gene="mraZ"
                     /locus_tag="RFE25_001787"
     CDS             13988..14419
                     /gene="mraZ"
                     /locus_tag="RFE25_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDU2816841.1"
                     /translation="MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYT
                     LDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKE
                     CTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF"
     gene            14435..15370
                     /gene="rsmH"
                     /locus_tag="RFE25_001788"
     CDS             14435..15370
                     /gene="rsmH"
                     /locus_tag="RFE25_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017724209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDU2816842.1"
                     /translation="MFHHISVMLNETIDYLNVKENGVYIDCTLGGAGHALYLLNQLND
                     DGRLIAIDQDQTAIDNAKEVLKDHLHKVTFVHSNFRELTQILKDLNIEKVDGIYYDLG
                     VSSPQLDIPERGFSYHHDATLDMRMDQTQELTAYEIVNNWSYEALVKIFYRYGEEKFS
                     KQIARRIEAHREQQPITTTLELVDIIKEGIPAKARRKGGHPAKRVFQALRIAVNDELS
                     AFEDSIEQAIELVKVDGRISVITFHSLEDRLCKQVLQEYEKGPEVPRGLPVIPEAYTP
                     KLKRVNRKPITATEEDLDDNNRARSAKLRVAEILK"
     gene            15384..15785
                     /gene="ftsL"
                     /locus_tag="RFE25_001789"
     CDS             15384..15785
                     /gene="ftsL"
                     /locus_tag="RFE25_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDU2816843.1"
                     /translation="MAVEKVYQPYDEQVYNSIPKQQPQTKPEKKTVSRKVVVQLTKFE
                     KVLYITLITVIAMLSIYMLSLKMDAYDTRGKIADLDYKIDKQSSENSALQSEIKKNSS
                     YERIYEKAKKQGMSLENDNVKVVRSNGEAKN"
     gene            15766..18000
                     /locus_tag="RFE25_001790"
     CDS             15766..18000
                     /locus_tag="RFE25_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDU2816844.1"
                     /translation="MAKQKIKIKKNKIGAVLLVGLFGLLFFILVLRISYIMITGHSNG
                     QDLVMKANEKYLVKNAQQPERGKIYDRNGKVLAEDVERYKLVAVIDKKASANSKKPRH
                     VVDKKETAKKLSTVIDMKPEEIEKRLSQKKAFQIEFGRKGTNLTYQDKLKIEKMNLPG
                     ISLLPETERFYPNGNFASHLIGRAQKNPDTGELKGALGVEKIFDSYLSGSKGSLRYIH
                     DIWGYIAPNTKKEKQPKRGDDVHLTIDSNIQVFVEEALDGMVERYQPKDLFAVVMDAK
                     TGEILAYSQRPTFNPETGKDFGKKWANDLYQNTYEPGSTFKSYGLAAAIQEGAFDPDK
                     KYKSGHRDIMGSRISDWNRVGWGEIPMSLGFTYSSNTLMMHLQDLVGADKMKSWYERF
                     GFGKSTKGMFDGEAPGQIGWSNELQQKTSSFGQSTTVTPVQMLQAQSAFFNDGNMLKP
                     WFVNSVENPVSKRQFYKGQKQIAGKPITKDTAEKVEKQLDLVVNSKKSHAANYRIDGY
                     EVEGKTGTAQVAAPNGGGYVKGPNPYFVSFMGDAPKKNPKVIVYAGMSLAQKNDQEAY
                     ELGVSKAFKPIMENTLKYLNVGKSKDDTSNAEYSKVPDVEGQDKQKAIDNVSAKSLEP
                     VTIGSGTQIKAQSIKAGNKVLPHSKVLLLTDGDLTMPDMSGWTKEDVIAFENLTNIKV
                     NLKGSGFVSHQSISKGQKLTEKDKIDVEFSSENVDSNSTNNSDSNSDDKKKSDSKTDK
                     DKSD"
     gene            18292..19257
                     /locus_tag="RFE25_001791"
     CDS             18292..19257
                     /locus_tag="RFE25_001791"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDU2816845.1"
                     /translation="MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKK
                     TGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKN
                     NQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFW
                     QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPY
                     NINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLT
                     GKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH"
     gene            19259..20608
                     /locus_tag="RFE25_001792"
     CDS             19259..20608
                     /locus_tag="RFE25_001792"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDU2816846.1"
                     /translation="MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLS
                     QDAHAKDLESMGISVVSGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEV
                     ELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPT
                     DYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDY
                     LICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEH
                     NLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLA
                     TQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKS
                     VIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY"
     gene            20624..21943
                     /locus_tag="RFE25_001793"
     CDS             20624..21943
                     /locus_tag="RFE25_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HDU2816847.1"
                     /translation="MDDKTKNDQQESNEDKDELELFTRNTSKKRRQRKRSKATHFSNQ
                     NKDDTSQQADFDEEIYLINKDFKKEESNDENNGSASSHANDNNIDDSTDSNIENEDYR
                     YNQEIDDQNESNGIAVGNEQPQSAPKEQNSDSNDEETVTKKERKSKVTQLKPLTLEEK
                     RKLRRKRQKRIQYSVITILVLLIAVILIYMFSPLSKIAHVNINGNNHVSTSKINKVLG
                     VKNDSRMYTFSKKNAINDLEEDPLIKSVEIHKQLPNTLNVDITENEIIALVKYKGKYL
                     PLLENGKLLKGSNDVKINDAPVMDGFKGTKEDDMIKALSEMTPEVRRYIAEVTYAPSK
                     NKQSRIELFTTDGLQVIGDISTISKKMKYYPQMSQSLSRDSSGKLKTRGYIDLSVGAS
                     FIPYRGNTSSQSESDKNVTKSSQEENQAKEELQSVLNKINKQSSKNN"
     gene            22049..23461
                     /gene="ftsA"
                     /locus_tag="RFE25_001794"
     CDS             22049..23461
                     /gene="ftsA"
                     /locus_tag="RFE25_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDU2816848.1"
                     /translation="MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNG
                     LIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEING
                     SHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAI
                     QKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYE
                     RGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQV
                     DSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKE
                     LLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDNEETEED
                     VIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQ
                     DKDKDKEESKFKKLMKSLFE"
     gene            23494..24666
                     /gene="ftsZ"
                     /locus_tag="RFE25_001795"
     CDS             23494..24666
                     /gene="ftsZ"
                     /locus_tag="RFE25_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDU2816849.1"
                     /translation="MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAIN
                     TDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVT
                     SGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDT
                     LIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIM
                     SNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQ
                     EAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTS
                     VNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR"
BASE COUNT         8891 a         3388 c         4569 g         7850 t
ORIGIN      
        1 ctgaatatat ttttaggaaa tgaaattatc catacactga ctgttttaat aacaacattg
       61 tatattgtta attcaagaaa ggggattaaa aatgacagag ttgaataata ttataaactc
      121 tcttcaatct ttgtttgagt ctgaatcagg ctataaaatt tcgaaaaatt caggagttcc
      181 atatcaaaca gtacaagatt taagaaatgg gaaaaccaaa ctagaagatg ctagatttag
      241 aacgattatt aaactttata gttactatgt ctcattaaaa gaacattaat catgggacaa
      301 taaagtattg ctataataat tgaatcatta aatgaaggaa tagagcctaa gacataataa
      361 atcaatgtct taggctctac aatattatat tggtagtagt tgaccgaatg aaaatgacca
      421 tgtaacaagc atttttgggg ccccaacaca gaagctgacg aaaagtcagc ttacaataat
      481 gtgcaagttg gggatgggcc ccaacacaga gaatttcaaa aagaaattct acagacaatg
      541 caagttgggg agtgacaacg aaataaattt tataaaatac catttctgtc acattcctac
      601 tcccaattcc atttaaatat atagaaaatt tcacctatta tatacatcat acactttaaa
      661 aattatcatt taaataatct gatttggaat taaagtgcat gaagtataag tcaccttcat
      721 atactaatca aagaggacgt caacagttat tttattagga tttttaacat aaacatttgc
      781 tagatctgaa tgtaatcttt tgcttaaatc aatagtgtag ttattaccgc caccggtgat
      841 cttaagctta cctttattac gattttcggt atataatatt ttatttttta ttaacgcttc
      901 tcgtgcacgg aaatcgattt ctttcaatgt taatactggt ttattgcctt ggtatatttt
      961 atgcgcacca ataatcgttt gtagtttatc tttgtattgc acaaaaagat tataagtttt
     1021 atcagaaggt tttgcggctg gtgtaacgcc acctgtaaat gtctctctat aagaccacca
     1081 taactgatca gtatctttgt cttttagtcc aaacacatct acgtaacgat cttttaactg
     1141 attaatattt ccccaacttt cagcgcccca taaagatata tgtgctgacc atgaatatct
     1201 cttaagttca acataaatgt tttcattatc atattgatat agccatttat ttgaaaatga
     1261 aaaatgaggc tgtgtgtaat atttaattaa ttcattgatg ttagtttcat cttgaccaat
     1321 gctataagct ttagcttcag agtaaaaact aaatactggt ttttgatttt gaggtaatac
     1381 agtacctaat agtaataatg ttgtcgttaa aattatattt ttcgtgatgt tcttactcat
     1441 tagaacatct cctttcagag gaatcatgat acgaggaata agaaatttaa atgtgagcga
     1501 agtcaatata gtatttgcga ttatttttat taactccatt attattgtta gtttgatttt
     1561 tcgaggataa cttcaatttt tgcattttga ggttttttaa catatctatt tgcatcagtt
     1621 gatggcaacc ttttacttaa atctattgtg tagttattgt ctgtacctgt tattttaatt
     1681 tgtcctttat tataagaatt attatataat tttttacttt taattaatgt ttgacgaata
     1741 cgaaaatcta attcttttaa agttaaaaca ggcttattgc cttcataaac tggaaatccg
     1801 ccagtaaacg tttctgcttt atctttatat gttacattca gtttatagtg tttatcgtta
     1861 gatgttgctg caggagtaac accaccagta aacgtttctt gagataatgc aaaagaatca
     1921 atggtttctt ggtcttttat gccaaaaata tcaacgcttt tatttcttaa ttggttgata
     1981 ttgccccaac tttcaggtcc ataaacttga atatgactat accaagaaaa ctgtaacaac
     2041 gttgcatgaa tcgtaccgtt atctttttgc cataacgtac tgttagagaa ggttaaatat
     2101 ttttgcgagt aatatttagt taactcatta acgttagttt cgttttgatt tatataataa
     2161 gctttcgctt cagatgaaga attgataggt gtattaggaa attgtgtaaa tgctgtacct
     2221 aatagtaaca atgttgttga taaaataatt tttttcgtga tgttattgtt cattcgaatt
     2281 tctcctttga gtattgttgg aatgtttaat tataaaaagg ggttaattag ataattgaaa
     2341 ttatccgcat ttacaaaagg taataggtta gttagatttt tcgagtatga cttcaatttg
     2401 tgcattttta ggatttttaa cataacggtt tgtgtcagtt aattttaact ttttacttaa
     2461 atcaatcgtg taattatttc catcagcagt tatcttaatt tgacctttat taaattctcc
     2521 gttatataac tttttattct ttattaatgt ttgacgaata cggaaatcta attcttttaa
     2581 agttaatact ggtttatttc ctttgtaaaa ttcatgtcca ccgatgatag tttgttgttt
     2641 atcactatat tttaaaaata gtctataagg tttatcagat gaagtagctg ctggcgtaac
     2701 accaccagta aatgtttcat cataagtcca gtaaccttca actgtgtcct catctttagt
     2761 tccaaatata tcaacgtatt tatttcttaa ctgattaatg tttccccaac tctcggatcc
     2821 aaacacttga atatgactat accaaaccca cgtttgcaat gttgcatgaa tgctaccatt
     2881 gggcttttgc catagccatt ttccagataa tgaaaaatgc ggctgagtgt aatatttgat
     2941 taactcattg atattagtct cgttttcact gatattatag gcttttgctt cagatgaaaa
     3001 actgattggt gttttaggaa gttgtgttga tgtggttcct aaaagtaaca atgctgttga
     3061 taaaactaat ttattcatga tgttcttttt catatgaaaa tctcctttgc gtgaattacc
     3121 caaagtatat aagctattac accgattcgg aattaaataa aagctaaaac tatgttaaat
     3181 aaacttaaac agttagtagt gttatttaag caaaacttat catttttaag ttttggacag
     3241 aaacagtact taataaagta ggcgggagtt atatattaaa aacgacacgt tacaattatt
     3301 ctctaatcaa ttgcattaaa ttgtttgata attgaatttt ctaactactt gaaaaatagt
     3361 tatactttaa atgtagtact tattttaatt atttcctact acttaaattt aatattaata
     3421 aaatgttcat ttaattattg ataaaatatt acaaatttta atagtaggtt gtgtttattt
     3481 tgtatgcgct tacaatttag gtgtaactaa aataaaagga gttgttatta atgaaaaatt
     3541 tacgaaacag aagtttttta actttattag acttttcacg acaagaggta gaattcttat
     3601 taacactctc cgaggattta aaacgtgcta aatatattgg cactgaaaag cctatgttaa
     3661 aaaataaaaa tattgcactg ttatttgaaa aagattctac aagaacgcga tgtgcatttg
     3721 aagttgcagc gcatgatcaa ggtgcaaatg taacttattt aggcccaact ggatcacaaa
     3781 tgggtaaaaa agaaacaact aaagatactg cacgtgtgct tggtggaatg tatgatggca
     3841 ttgaataccg tggtttttca caaagaacag tagaaacttt agctgaatat tcaggcgtac
     3901 cagtgtggaa tggtttaact gatgaagatc atcctactca agttcttgct gatttcttaa
     3961 cagcaaaaga agtcttaaaa aaagattatg cagatattaa ctttacatat gttggagatg
     4021 gtcgtaataa cgttgcaaat gcattaatgc aaggtgctgc cattatgggt atgaacttcc
     4081 atttagtttg tccaaaagaa ttaaatccaa cagatgaatt attaaatcgc tgtaaaaata
     4141 ttgccgctga aaatggtggc aacatattaa tcacagatga tattgaccaa ggtgtaaaag
     4201 gttcggatgt aatttacact gatgtttggg tatcaatggg tgaacctgat gaagtatgga
     4261 aagaacgact tgaattattg aaaccatatc aagtaaataa agaaatgatg gataaaactg
     4321 gtaatccaaa tgttattttt gagcattgct taccatcttt ccataatgct gatacgaaaa
     4381 ttggtcaaca aatttttgaa aaatatggta ttcgagaaat ggaagttaca gatgaagtat
     4441 tcgaaagtaa agcttcagtt gtattccaag aagctgagaa cagaatgcat acaatcaaag
     4501 cagtcatggt tgctacattg ggtgaatttt aaatgatata aggaagtgaa tatgatggcg
     4561 aaaatagtag tagcattagg tggtaatgct ttaggaaaat cacctcaaga acaactcgag
     4621 cttgttaaaa atactgcgaa atcattagta ggattaataa caaaaggaca tgagattgtt
     4681 attagtcatg gtaatggacc acaggttgga agcattaatt tgggacttaa ctatgctgca
     4741 gaacataacc aaggtccggc atttccattt gctgaatgtg gcgcaatgag tcaagcttac
     4801 atcggctatc aattacaaga aagcttacaa aatgaattgc attctattgg aatggataaa
     4861 caagtggtaa cactagtgac acaagttgaa gttgatgaaa atgatccggc atttaacaat
     4921 ccttcaaaac caattgggtt attttacaac aaagaagaag ctgaacaaat tcaaaaagaa
     4981 aaaggattta tatttgttga agatgctgga agaggatata gacgcgttgt tccttcacca
     5041 caacccatct ctattattga attagagagt attaaaacac ttattaaaaa tgatacactc
     5101 gttattgctg ctggtggtgg aggtatacca gtaattagag agcaacatga tggttttaaa
     5161 ggtattgatg cagttataga caaagataaa acaagtgcgt tgttgggtgc taatattcaa
     5221 tgcgatcaat tgattatttt aacagcaatt gattatgtat atattaattt taacactgaa
     5281 aaccaacagc ctttgaaaac aacaaatgtt gatgaattaa aacgatatat agacgaaaat
     5341 caatttgcaa aaggaagtat gttaccaaaa attgaagcag ccatatcatt tattgaaaac
     5401 aatccaaaag gaagtgtgct tataacatca ttaaatgaat tagatgctgc cttagagggt
     5461 aaagtaggta ctgtgattaa aaagtaattg aattgaaacg cttttcaatt actatatgtc
     5521 aaatgcatga tttttattat ttatgtgcac cccctgaaaa taatgcctct attttgatgc
     5581 ggggtgcact ttcttaattt atatttataa aatctttaag gtagaaatgc taggttaaat
     5641 gtcgaaggag atgaaaccgt ggaaaataca attaatgaaa gtgaaaagaa aaaacgattt
     5701 aaattaaaaa tgccaggtgc atttatgatt ttattcattt taacggttgt tgcagttata
     5761 gcaacatggg ttattcctgc tggtgcatat tctaaacttt cttacgaacc ttcatcccaa
     5821 gaactaaaga tagttaaccc tcataaccaa gtgaaaaagg ttccgggtac gcaacaggaa
     5881 ctagacaaaa tgggggttaa aattaagatt gaacaattta aatcaggtgc aattaataag
     5941 ccagtatcaa ttccgaatac ttatgaaaga ttaaagcaac atccagctgg accagaacaa
     6001 ataacaagta gcatggttga aggtacgata gaagcggtcg atatcatggt attcattctt
     6061 gtactagggg gacttattgg cgtagttcaa gccagtggtt cttttgaatc gggattgtta
     6121 gctttaacga agaaaacaaa agggcatgaa tttatgctaa ttgtgtttgt atcaatacta
     6181 atgattatcg gcgggacgtt atgtggtatt gaagaagaag ctgtagcatt ctatccgatt
     6241 ttagtcccta tatttatagc gttaggatac gattctatcg tttcagttgg tgccatattc
     6301 cttgccagct ctgtcggtag tacattttca actattaacc cgttctcggt tgtaattgcc
     6361 tctaatgccg ctggtacaac ttttacggat ggcttgtatt ggagaatagg tgcttgtatt
     6421 gtcggtgcga tttttgttat tagttattta tattggtact gtaaaaaaat taaaaacgat
     6481 cctaaagcgt catattctta tgaagacaaa gatgcttttg aacagcaatg gtctgtatta
     6541 aaagatgacg atagtgccca ttttactttg cgtaagaaga taatccttac attatttgta
     6601 ctaccatttc caattatggt atggggagtt atgacgcaag gttggtggtt cccagttatg
     6661 gcttcagcat ttttaatatt tacaattata ataatgttta ttgctgggac aggtaaatct
     6721 ggattgggag aaaaaggaac tgtagatgca tttgtcaatg gtgcatcaag tttagtaggt
     6781 gtatctttaa ttattggttt agctcgaggt attaatttag tgttgaatga aggtatgatt
     6841 tcagatacaa tcttacactt ttcatcatct ttagttcaac atatgagtgg accattattt
     6901 atcatcgtat tactatttat tttcttctgt ttaggtttta tcgtgccatc atcttctgga
     6961 ttagcggtat tatcaatgcc tatctttgca ccactagctg atacagtagg tataccaaga
     7021 ttcgtcatcg ttacgacata tcaatttggt caatatgcga tgttattctt agcgccgact
     7081 ggacttgtta tggccacact acaaatgtta aacatgcgat attcacattg gttccgattt
     7141 gtatggccgg tagttgcttt tgtattgatt ttcggtggcg gagtactaat tacgcaagta
     7201 ctaatttatt cataatttga aatgctatat tataaaaata ctaattgggt tttatgcatc
     7261 tcgtaggttt gtagaaatac taaactaagc gaggtgcatt attatttttg attaagaaaa
     7321 taatgacggt aatgataaca ctagtaagta attgatacaa tgctctattt aataatgata
     7381 tttttaaaat ttgtttttaa tgtaatgtta gatctatggt atattatatt tatcgtggta
     7441 aatatgtatt tgctgtaaac agtttttgta acacatgaca catatggttg tgaaaatagc
     7501 atatataaag gatggctata aatgacacat ttgacaaagg ttttagatac actaactgga
     7561 atatgcgtag tattattatt tagtaaatat tttgtggcgt atgcaaatat ggtgtttgat
     7621 tggaatttaa gatggtattt gctagaaaac ataccacatt tgccaattat attatttatt
     7681 ctgatgttta ttttcggagt accttctgaa atgataaaag ataggcaaag gaaaaataac
     7741 ggtgtttaat ttatcgatat ttagaggtga taaaatttgt caactattac aaagactaaa
     7801 ataaaaatct ttattaatta ttttattggt atattagcct tggcgtttgc tgcttatata
     7861 ttatttaaat aaaggttaga gtgaaacgtg tttatgaact agacgttcta gtatagttac
     7921 tacagcttta gtcagaaggt atcattgata agatcatatt aaatcaaaga ggcattgata
     7981 tacactaaaa agaggcaaga ttacctgcct cttttttagt tattaaatat gcgtgttaat
     8041 tcttggtaat agtgttactg agacgcatta cgaagaaatt tatcttgatt ttcctttttt
     8101 aaaaagaagt gaagatatcc tataaagact ctaagtacta ttacagtggc taataacact
     8161 tcgataaaca aaagaccttt ccaaatatct ggaaacataa gtacaggcaa actgttcttt
     8221 aaagcagttg ctgagattac taaagggaat gtgaaagctg aaaatacggg cgaaaaaggt
     8281 tcttttagta atttaggcaa ttgtataatg atataaaaat aaaatatttg agctaatatt
     8341 aaaaatataa ttacgataaa agcattcgcc ttaggaaagg ctataacata tgctgcagcg
     8401 actaaagaaa atggtgcaca aattgtcgat gtgttcggtt tgattgacgt ctgcaatgga
     8461 aatgctttta atcgcttgaa aacaataggt aagacaatac aagtagctac aaagccatat
     8521 attactgtta attgacctat gaaaaaacat ccgctaacgg gtgccgtcaa tcctgcgata
     8581 gcaataccaa taaaaagtac agtccacgaa ggataaacat tttcaagtga aaaatctttt
     8641 aaatatttta ttgaaaaaat aatcatatgc gtcataattc ccacaaggca taaaatccaa
     8701 ataggcgtta ttaagctatt gataaaagtt atgttactaa aaaatgtatt taaataagta
     8761 gtacctaaaa agccagacat gaaaaatgtt gtgaacactg atgaaactag aggactgttt
     8821 aattgttctt tcacattatt aaaatatttg atcatagtac ataaaaggtg aatccaaatc
     8881 aagaaagcaa agattccgca aacagcgttt aaagtaagag ataagtcttt taatagatta
     8941 cccaggccta ataatcctaa gactagtcct gacgttacta gaggtgcttt ttgaagtctc
     9001 atgatttaca acctttctta tgtgattttc ttcactaatt atatcatgat agctatggcc
     9061 aattaataag aagagtgtgt actattacgt tattagagta tgtatattgg attgatagac
     9121 acataattga catttaaatc tcaaaattaa tgatatttga ggtatgcttt gcaacctaaa
     9181 tattggaata tgtggaaaag taattattta atttaaatga tgattgaaga tttacaaggg
     9241 ggtgtacaaa atgagaaatc aaattcaaaa actattagac agtgatttga gcagtttaca
     9301 tatatcgaaa caaacaggag ttccacaaag cacaatacac agaatgagaa aaaagaaaga
     9361 tcattagaca atatgtcatt gaaaaacgct gaactacttt ataaatttgc caatagtata
     9421 tttagcaatg aaaattaaga agaataatta gtgagttaaa taattaaaaa accacgtctc
     9481 gatggacgtg gttatttttt taaatgtatt taattatagg atttcgggcc cctgaaaagt
     9541 ccctaaaatt ttgaatagta tcaaaatcta taggaataat ataataataa aaatctctac
     9601 gcatgcaaat ggtgagtgtt aaaaatcttg gtgtagtgtt ggtgtagttc aggtgcagta
     9661 tagatgaaat ttgagcacaa aattacttaa ttaaaaatgt ataaacaagt gtcagacgcg
     9721 tgtcaattgt gtgtcaaaaa attctatgac gaataagcat gcttgtttta attactgtat
     9781 tttcggggct tatgcggggg acgttttggt gacgcatcat actatattac tgaaattcaa
     9841 aacaaaaaga gccccgtaat cacggaactc ttttgtttgg taatgcgtat aaaaatacct
     9901 ataaacgtcc tgggagggat tcgaaccccc gaccgatggc ttagaaggcc attgctctat
     9961 ccagctgagc taccaggaca cgtttaacaa cacaagaatt attatatcta aatgaactta
    10021 aattagcaat accttgtaaa taaaaaatgt ttatattttt cactattata gagctattta
    10081 tctaaaaagg ttcaataaga cttaaatgcg aattcaggca acttaattgt gttaaataca
    10141 gttttgaatg cctaactgta tttcttttct ctttaaaata cagttaagta cattataaga
    10201 tgttgtgcgg ataaacaaac taattgcatc aaatttattt taaaataaca acaacaaaac
    10261 gttaagcgaa taacatttcg gtgatttaaa agctacgcac gtttttgtta tcttcaaatt
    10321 taaattttaa ggagtgtttt caatggaagg tttatttaac gcaattaaag ataccgtaac
    10381 tgcagcaatt aataatgatg gcgcaaaatt aggcacaagc attgtgagca tcgttgaaaa
    10441 tggcgtaggt ttattaggta aattattcgg attctaattt caatatgtta tgtaagtaat
    10501 cagtattatt tcaaaggtga gggagagatt taaatgactg gactagcaga agcaatcgca
    10561 aatactgtgc aagctgcaca acaacatgat agtgtgaaat taggcacaag tatcgtagac
    10621 atcgttgcta acggtgtggg tttactaggt aaattatttg gattctaata taataactaa
    10681 tattctttaa aataaactgg gtgagcatac tttaatgtta tgcactcagt ttattttatt
    10741 tgcagaaatt tgagcctctg ttaagattta gatacataga caatatagga gatggggaaa
    10801 ttgggatata aaaatatttt gatagacttt gatgatacaa ttgttgattt ttatgatgca
    10861 gaagaatggg cgtttcacta tatggcgaat gtttttaatc ataaagcaac aaaggatgat
    10921 tttttaacat ttaaaaaaat caatcaccaa cattgggaag cttttcaaca aaataaatta
    10981 acgaagtctg aagtattatc agaacgattt gtgaattact tcaaacatca tcaaatggaa
    11041 gttgatgggc atcgtgcaga tgtgttattt agaaatggat tagcagaagc taaagttaaa
    11101 tactttgatc aaacattaga aacaattgtc gaattatcga aaagacatga tttatatatt
    11161 gttactaatg gtgtaaccga aacgcaaaag agaaggttaa atcagacgcc gttgcataaa
    11221 tatattaaaa agatatttat atctgaggaa acaggatatc aaaaacctaa tccggaattt
    11281 tttaattatg tttttaatga tattggtgag gatgaaagac agcactcgat tatagttgga
    11341 gattctttaa catctgacat tctaggtgga atcaatgcgg gtatagctac ttgctggttt
    11401 aattttagag gatttgatca taatccagga attatacctg attatgaaat taattcatgg
    11461 aaacaactaa atgatattgt acgttaagac aaataatttg aaaatgattt acttatatta
    11521 gcttaagaaa gtaattgtaa aaacgacact acgaaaagat gcattttcat gctcgtagtg
    11581 tcgaatatta ttatcttatg gtttccacaa taagacatca tgtccctcta tatttttagc
    11641 ttccacatct gtaaatccat gatgtaaaaa gaaatcctta gaatcatttc tgccaatggc
    11701 tttaattggc atattgaaac tctttgcaaa atcaatcaat tctgaagcgt accctctgtt
    11761 ttgatatttt ggtaatactt ctaacttcca taataatata taatcttcaa aatctgggaa
    11821 gtagatttct tcgacatcac ctttttttag taatgccatt ctagctccta attgatctcc
    11881 gacaaatatg ccataaaatg gtgaatctga acttgcatca atcatttgac cgtttaactc
    11941 attgaccatg tataagtctt tgttgccaaa cgctctaaag ttttcgaata attcgtcagt
    12001 tttgtaatta atttcaagac gtttgatttc actcatattt atctacccct tatttgttta
    12061 ctactattat tatacattaa accacttgtg tttttcattg atttgaaaat gtaaaacaat
    12121 gaacattata aattttccat gattaaattg attttcaagc cgtaaaattg tcaatcaccg
    12181 gtatagactt tatactatag tttgtaatcg cgtacttaag gagaaaaaac atggactgta
    12241 aagtagttag tttaaatgaa aaagatcagt ttataccaaa aataaagagc agtgaccctg
    12301 taataacagg attatttcaa tatgatgcag ctcaacaaac tagttttgaa aaaaggatgt
    12361 ctaaagaaaa taatggaaga gaagcggcat tagcgaatgt tattcgtgaa tatatgagtg
    12421 atttaaagct ttcaaatgaa caagaattaa acatacaaca tttagctaat ggttcaaaag
    12481 ttgtgattgg tggacaacaa gcagggcttt tcgggggacc attgtataca ttccataaaa
    12541 tattttcaat cattacttta tctaaggaat taacggatac acataagcaa caagtagtac
    12601 cagttttttg gattgcagga gaagatcatg atttcgatga agtgaatcat acatttgttt
    12661 ataacgaaaa tcatgggtcg ctgcataagg ttaaatatca tacaatggag atgccagaga
    12721 cgacagtctc tagatattat cctgataagg ctgagttgaa acaaacttta aaaacgatgt
    12781 tcattcatat gaaagaaact gttcatacac aaggtctact ggagatttgt gacagaatta
    12841 ttgaccaata tgactcgtgg actgatatgt ttaaagcact actgcatgaa acatttaaag
    12901 catatggcgt tctatttata gatgcgcagt ttgagccgtt aagaaaaatg gaagcgccta
    12961 tgtttaaaaa gattttgaaa aaacatcagt tgcttgatga tgcttttaga gcaacacaac
    13021 aacgtactca aaatcaaggc ttgaatgcga tgatacaaac agatacaaat gttcatttat
    13081 tcttacatga tgaaaatatg cgccaattag tttcgtatga tggtaagcat tttaaattaa
    13141 ataaaacaga taagacatat ataaaggaag aaattataaa tattgcggaa aatcaacctg
    13201 aattattttc taataatgta gtgacaagac cattaatgga agaatggtta tttaacacgg
    13261 tggcatttgt tggaggaccg agtgaaatta agtactgggc tgaactaaaa gatgtatttg
    13321 aactatttga tgttgaaatg cctatcgtga tgccaaggct tagaattact tatttaaatg
    13381 accgtataga aaaattactt tcgaaataca atattccatt agaaaaagtg ttagtcgatg
    13441 gtgttgaagg agaaagaagt aagtttatta gagaacaagc atcacatcaa tttattgaaa
    13501 aggtagaagg tatgattgaa caacagcgtc gtctaaacaa agacttatta gatgaagtgg
    13561 cggggaatca aaataatatt aaccttgtga ataaaaataa tgaaattcat atacaacagt
    13621 atgattattt gttaaaacgt tatcttttaa acattgaaag agaaaacgac atcagtatga
    13681 agcaatttag agaaattcaa gaaacactcc atccaatggg aggattacaa gaaagaatat
    13741 ggaatccact tcaaattttg aatgattttg ggacagatgt gttcaagccc tccacctatc
    13801 caccactttc ttacactttt gatcatatta ttataaaacc ttgatatacc aagggtttag
    13861 cccgatttat cttaatgata aatcgggcat ttttttgttt tttaaaataa atttcacaaa
    13921 ttttgtataa atagtggtgg atagtgggga gatgtggtaa attatatata aggtgaggtg
    13981 ataaaaaatg ttcatgggag aatacgatca tcaattagat acaaaaggac gtatgattat
    14041 accgtccaag tttcgttatg acttaaatga gcgttttatt atcacaagag gccttgataa
    14101 atgtttattc ggttacactc tagacgaatg gcaacagatt gaagagaaaa tgaaaacctt
    14161 acctatgaca aaaaaagacg cacgtaagtt tatgcgtatg ttcttctctg gtgctgttga
    14221 agtagaactt gataagcaag ggcgtattaa catccctcaa aacttgagga aatacgctaa
    14281 tttaactaaa gaatgtacag taatcggtgt ttcaaatcgt attgagattt gggatagaga
    14341 aacttggaat gatttctatg aagaatctga agaaagtttc gaagatattg ctgaagattt
    14401 aatagatttt gatttttaaa atggaggaat tgaagtgttt catcatatca gcgttatgtt
    14461 aaacgaaacc attgattatt taaatgtaaa agaaaatggt gtgtacattg actgtacgct
    14521 aggtggagcg ggacatgccc tttatttact aaatcaatta aatgacgacg gaagattaat
    14581 agcaatcgat caagaccaaa ctgcaattga taatgctaaa gaggtattaa aggatcattt
    14641 gcataaggtg acttttgttc atagcaactt ccgtgaatta actcaaatat taaaagactt
    14701 aaacattgaa aaagtagatg gaatttatta cgacttgggt gtttcaagcc cacaactcga
    14761 cattccagaa cgaggattca gttatcacca tgacgcaaca ttagacatgc gtatggacca
    14821 aacacaagaa ctaacagcat atgaaattgt taacaattgg tcatatgaag cgttagtgaa
    14881 gattttttat cgttatggcg aggagaaatt ttcaaaacag atagctcgaa gaatcgaagc
    14941 acatcgtgaa caacaaccaa taacaacaac attagaatta gttgacatta taaaagaagg
    15001 tattcctgca aaagcaagaa gaaaaggcgg acatcctgca aaacgagtat ttcaagcact
    15061 acgaattgca gtaaacgatg aattgtcagc ttttgaagat tcaatagaac aagcgattga
    15121 attagtgaaa gtagacggca ggatttcggt aatcactttc cattctttag aagatcgttt
    15181 atgtaaacag gtgttacaag aatatgaaaa aggtccagag gtaccaagag gattgccagt
    15241 tataccagaa gcatatacac ctaagttaaa gcgtgttaat cgtaaaccga ttaccgctac
    15301 agaagaagat ttagatgaca ataacagagc acgaagcgcg aaattacgtg tagctgaaat
    15361 acttaaataa ggagcaattt ataatggctg tagaaaaagt gtaccaacca tatgacgaac
    15421 aagtttataa tagtataccg aagcaacaac cacaaactaa gcccgaaaag aagactgttt
    15481 cgagaaaagt ggttgtacaa ttaactaaat ttgaaaaagt tttatacata actttgatta
    15541 ctgtaattgc tatgttaagt atttatatgc tatctttaaa aatggatgcg tatgatacgc
    15601 gaggaaagat tgcagattta gattataaaa tagataaaca atcaagtgaa aacagtgctt
    15661 tacaatctga aatcaaaaag aattcttctt atgaacgcat atacgaaaag gctaagaaac
    15721 aggggatgag ccttgagaac gataatgtaa aggtagtgcg tagtaatggc gaagcaaaaa
    15781 attaaaatta aaaaaaataa aataggggca gtcctacttg ttggtttatt cggactgctc
    15841 ttttttatat tggttttaag aatttcatat atcatgatta ctggacattc taatggtcaa
    15901 gatttagtca tgaaggcaaa tgaaaagtat ttagttaaga atgcacaaca accagaacga
    15961 ggaaagatat atgatcgtaa tggtaaagtg ctagcagaag atgtagaaag atataaactt
    16021 gttgcagtaa tagataaaaa ggcgagtgcc aattctaaaa aacctaggca tgtagttgat
    16081 aaaaaagaga ctgcaaagaa attatctaca gtcattgata tgaagccaga ggaaattgaa
    16141 aagagactta gtcaaaagaa agctttccaa attgaatttg gacgcaaagg aacaaattta
    16201 acgtatcagg acaaattgaa aatagagaaa atgaatttgc ctggtatttc tttattgcct
    16261 gaaacagaac gcttttatcc aaatggcaat tttgcatcac acttaattgg tagagctcag
    16321 aaaaatccgg atactggtga acttaaaggt gcacttggag ttgaaaagat ttttgatagt
    16381 tatttaagtg gatctaaagg atcattgaga tatattcatg atatttgggg atatatcgca
    16441 ccaaatacta aaaaagagaa gcagcctaaa cgtggtgatg atgtccattt aacaatcgat
    16501 tcaaatattc aagtatttgt tgaagaagct ttagatggca tggttgaaag ataccagccg
    16561 aaagatttat ttgcggttgt catggatgcc aaaactggag aaattttagc atacagtcag
    16621 cgaccaacat ttaatcctga aactggtaaa gactttggta aaaagtgggc aaatgacctt
    16681 tatcaaaaca catacgagcc tggatcaaca tttaaatcat atgggttagc agctgctatt
    16741 caagaaggtg cttttgatcc tgataagaaa tataaatctg gacatagaga tattatgggt
    16801 tcacgtattt cagactggaa tagagtcggt tggggtgaaa tcccaatgtc actcggattt
    16861 acttattcat ctaatacatt gatgatgcat ttacaagatt tagttggtgc agacaaaatg
    16921 aaatcttggt atgaacgatt tggatttgga aaatcaacta aaggtatgtt tgatggagaa
    16981 gcacctggtc aaattggatg gagtaatgag ttgcaacaaa aaacgtcatc atttggtcaa
    17041 tcgacaacag taacacctgt tcaaatgtta caggcgcaat cagcgttctt taatgatggt
    17101 aatatgttaa aaccatggtt tgtgaatagc gttgaaaatc ctgttagtaa aagacaattt
    17161 tataaaggtc aaaaacaaat cgcaggcaaa ccaataacaa aagatactgc tgaaaaagtt
    17221 gaaaagcaat tggatttagt tgtgaatagt aagaagagtc acgctgcaaa ctatcgtatt
    17281 gatggttatg aggtcgaagg taagactggt acagcacaag tcgctgcacc taatggtggt
    17341 ggatacgtta aaggtccaaa cccatatttt gtaagtttta tgggtgacgc accgaagaaa
    17401 aatcctaaag ttattgtata cgctggtatg agcttggcac aaaaaaatga ccaagaagct
    17461 tatgaattag gtgttagtaa agcgtttaaa ccaataatgg aaaatacttt gaaatattta
    17521 aatgtaggta aatcaaaaga tgacacatct aatgcagagt atagtaaagt gccagatgtt
    17581 gaaggtcaag acaaacaaaa agctattgat aatgtgagtg caaaatcatt agaaccagtt
    17641 actatcggtt ctggcacaca aataaaagca caatctataa aagcagggaa taaagtctta
    17701 cctcatagta aagtactgtt attaacagac ggagacttaa ctatgcctga catgtcagga
    17761 tggacgaaag aagatgtcat tgcttttgaa aacctaacaa atattaaagt aaatttaaaa
    17821 ggtagcggtt ttgtgtccca ccaatcaatt agtaagggac aaaaacttac tgaaaaagat
    17881 aaaatagacg tagaattttc atcagagaat gtagacagca attcgacgaa taattctgat
    17941 tcaaattcag atgataagaa gaaatctgac agtaaaactg acaaggataa gtcggactaa
    18001 caagaatggc tacattaaat aagggtgtat tgtcactatt tgtttttact aaagtaatgc
    18061 tgtgatagaa aaaaacatct tcatttaatc tttataaata agtgttgata gagaatttta
    18121 aggtagacga ggtcggatta acttgtttgt tataggcaaa ctttttatac tggcctctta
    18181 tgccgtaaaa aagaaaaatt ataaattttg attacaactt tgtttattta attgaaaaat
    18241 tgataatata ttagtggtta aaaaagtctg gattaagaag aggagatagt tatgattttt
    18301 gtatatgcgt tattagcgct agtgattaca tttgttttgg tacctgtttt aatacctaca
    18361 ttaaaaagga tgaaatttgg tcaaagtatt cgagaagaag gtccacaaag ccatatgaag
    18421 aagactggta caccaacgat gggtggacta acatttctat taagtattgt gataacgtct
    18481 ttggtggcta ttatatttgt agatcaagct aatccaatca tactgttatt atttgtgacg
    18541 attggttttg ggttaattgg ttttatagat gattatatta ttgttgttaa aaagaataac
    18601 caaggtttaa caagtaaaca gaagtttttg gcgcaaattg gtattgcgat tattttcttt
    18661 gttttaagta atgtgtttca tttggtgaat ttttctacga gcatacatat tccatttacg
    18721 aatgtagcaa tcccactatc atttgcatat gttattttca ttgttttttg gcaagtaggt
    18781 ttttctaatg cggtaaattt aacagatggt ttagatggat tagcaactgg actgtcaatt
    18841 atcggattta caatgtatgc catcatgagc tttgtgttag gagaaacggc aattggtatt
    18901 ttctgtatca ttatgttgtt tgcactttta ggatttttac catataacat taaccctgct
    18961 aaagtgttta tgggagatac aggtagctta gctttaggtg gtatatttgc tacgatttca
    19021 atcatgctta atcaggaatt atcattaatt tttataggtt tagtattcgt aattgaaaca
    19081 ttatctgtta tgttacaagt cgctagcttt aaattgactg gaaagcgtat atttaaaatg
    19141 agtccgattc atcatcattt tgaattgata ggatggagcg aatggaaagt agttacagta
    19201 ttttgggctg ttggtctgat ttcaggttta atcggtttat ggattggagt gcattaagat
    19261 gcttaattat acagggttag aaaataaaaa tgtattagtc gtcggtttgg caaaaagtgg
    19321 ttatgaagca gctaaattat taagtaaatt aggtgcgaat gtgactgtca atgatgggaa
    19381 agacttatcg caagatgctc atgcaaaaga tttagaatct atgggtattt ctgttgtaag
    19441 tggaagtcat ccattaacat tgcttgataa taatccaata attgttaaaa atcctggaat
    19501 accttataca gtatctatta ttgatgaagc agtgaaacga ggtttgaaaa ttttaacaga
    19561 agttgagtta agttatctaa tctctgaagc accaatcata gctgtaacgg gtacaaatgg
    19621 taaaacgaca gttacttctc taattggaga tatgtttaaa aaaagtcgct taactggaag
    19681 attatccggc aatattggtt atgttgcatc taaagtagca caagaagtaa agcctacaga
    19741 ttatttagtt acagagttgt cgtcattcca gttacttgga attgaaaagt ataaaccaca
    19801 cattgctata attactaaca tttattcggc gcatctagat taccatgaaa atttagaaaa
    19861 ctatcaaaat gctaaaaagc aaatatataa aaatcaaacg gaagaagatt atttgatttg
    19921 taattatcat caaagacaag tgatagagtc ggaagaatta aaagctaaga cattgtattt
    19981 ctcaactcaa caagaagttg atggtattta tattaaagat ggttttatcg tttataaagg
    20041 tgttcgtatt attaacactg aagatctagt attgcctggt gaacataatt tagaaaatat
    20101 attagcagct gtgcttgctt gtattttagc tggtgtacct attaaagcaa ttattgatag
    20161 tttaactaca ttttcaggaa tagagcatag attgcaatat gttggtacta atagaactaa
    20221 taaatattat aatgattcca aagcaacaaa cacgctagca acacagtttg ccttaaattc
    20281 atttaatcaa ccaatcattt ggttatgtgg tggtttggat cgagggaatg aatttgacga
    20341 actcattcct tatatggaaa atgttcgcgc gatggttgta ttcggacaaa cgaaagctaa
    20401 gtttgctaaa ctaggtaata gtcaagggaa atcggtcatt gaagcgaaca atgtcgaaga
    20461 cgctgttgat aaagtacaag atattataga accaaatgat gttgtattat tgtcacctgc
    20521 ttgtgcgagt tgggatcaat atagtacttt tgaagagcgt ggagagaaat ttattgaaag
    20581 attccgtgcc catttaccat cttattaaag ggtgtgagta ttgatggatg ataaaacgaa
    20641 gaacgatcaa caagaatcaa atgaagataa agatgaatta gaattattta cgaggaatac
    20701 atctaagaaa agacggcaaa gaaaaaggtc aaaggctaca catttttcta atcaaaataa
    20761 agatgataca tctcaacaag ctgattttga tgaagaaatt tacttgataa ataaagactt
    20821 caaaaaagaa gaaagcaatg atgaaaataa tggttctgct tctagtcatg cgaatgataa
    20881 taatatcgat gattctacag actctaatat tgaaaatgag gattatagat ataatcaaga
    20941 aattgacgac caaaatgaat cgaatggaat tgcagtcggc aacgaacaac ctcaatcagc
    21001 tcctaaagaa caaaatagcg actcgaatga tgaggaaaca gtaacgaaaa aagaacgaaa
    21061 aagtaaagta acacaattaa agccattaac acttgaagaa aagcggaagt taagacgtaa
    21121 gcgacaaaaa cgaatccaat acagtgttat tacaatatta gtattgttga ttgctgttat
    21181 attaatttac atgttttcac cacttagtaa aattgcgcat gtaaatataa atggaaataa
    21241 tcacgttagt acttcaaaga taaacaaagt tttaggtgtt aaaaatgatt cgaggatgta
    21301 tacgtttagt aaaaaaaatg ctattaatga tctcgaagag gatccattaa tcaaaagtgt
    21361 tgagatacac aagcaattac caaacacatt aaacgtagat atcacagaaa atgaaattat
    21421 tgctttagtg aaatataaag gtaaatattt acctttatta gaaaatggta aattgcttaa
    21481 aggttcaaat gatgtcaaaa ttaatgatgc acctgtcatg gatggtttca aaggtacaaa
    21541 agaagatgat atgattaagg cgttatctga aatgacacct gaagttagac gatatattgc
    21601 cgaagtgaca tacgccccaa gtaaaaacaa acaaagcaga attgaattgt ttacgacaga
    21661 tggacttcaa gtaatcggtg atatttcgac gatatctaag aaaatgaaat attatccgca
    21721 gatgtcacaa tcattatcaa gggatagttc gggtaaacta aaaacaagag gctatattga
    21781 tttatcagtc ggtgcttcat ttatcccata ccgtggaaac acgtctagtc aatcagaaag
    21841 cgataaaaat gtgactaaat catctcaaga ggaaaatcaa gcaaaagaag aattacaaag
    21901 cgttttaaac aaaattaaca aacaatcaag taagaataat taaaaaattt tgatattgtc
    21961 tatgtttata gttcacaagc cattcaacgt attgtaaact aaggatagtg tattttttta
    22021 atagtaattt gtcaggaggt gcctatctat ggaagaacat tactacgtaa gtattgatat
    22081 tggatcatca agcgtaaaaa caatagtagg cgagaaattt cacaatggta taaatgtgat
    22141 aggtacagga caaacctaca cgagcggtat aaaaaatggt ttaattgatg attttgatat
    22201 tgcgcgacaa gcaatcaaag acacaattaa aaaggcatca atcgcttcgg gtgttgatat
    22261 taaagaagtt ttcctgaaat tacctatcat tggaacggaa gtttatgatg aatcaaatga
    22321 aatcgacttt tatgaggata cagaaatcaa cggttcacat atcgaaaaag tattagaagg
    22381 tattagagaa aaaaatgatg tgcaagaaac agaagtaatt aatgtgttcc cgattcgttt
    22441 tatagtcgat aaagaaaatg aggtttcaga ccctaaagaa ttaattgcca gacattcatt
    22501 aaaggttgaa gcaggcgtaa ttgctattca aaaatcgatt ttaattaata tgattaaatg
    22561 cgtagaagca tgtggtgttg atgtattaga tgtttactct gatgcatata actatggttc
    22621 aatcctaaca gctactgaaa aagagttagg tgcatgtgtc attgatattg gtgaagacgt
    22681 tacgcaagtt gctttttatg aacgcggtga attagtagat gctgattcta tcgaaatggc
    22741 agggcgtgat attacagacg atattgcaca aggattaaac acttcttatg aaactgctga
    22801 aaaagttaaa caccaatatg gtcatgcatt ctatgattct gcttcagatc aagatatctt
    22861 cactgttgaa caggttgata gtgatgaaac agtacagtat actcaaaaag atttgagtga
    22921 ctttattgaa gcgcgtgtag aagaaatatt cttcgaagta tttgatgttt tacaagattt
    22981 aggattaaca aaagtaaatg gtgggtttat tgtaactggt ggatctgcaa acttacttgg
    23041 cgtaaaagaa ttattatcag atatggtaag tgaaaaagtt agaattcaca cgccatcaca
    23101 aatgggaatt agaaaacctg aattttcttc agcaatttct acaatttcta gtagtatcgc
    23161 ttttgatgag ttattagatt atgttacaat taattatcat gataatgaag aaactgaaga
    23221 agatgttatt gatgtgaaag acaaagataa cgaatctaaa ttaggcggat ttgattggtt
    23281 taaacgtaaa acaaacaaaa aagatactca tgaaaatgaa gtagagtcaa cagatgaaga
    23341 aatttatcaa tcagaagata atcatcagga acataaacag aatcatgaac atgttcaaga
    23401 caaagataaa gataaagaag aaagtaaatt caaaaaacta atgaaatctc tatttgaatg
    23461 attattggcc aataaaacta ggaggaaatt taaatgttag aatttgaaca aggatttaat
    23521 catttagcga ctttaaaggt cattggtgta ggtggtggcg gtaacaacgc cgtaaaccga
    23581 atgattgacc acggaatgaa taatgttgaa tttatcgcta tcaacacaga cggtcaagct
    23641 ttaaacttat ctaaagctga atctaaaatc caaatcggtg aaaaattaac acgtggttta
    23701 ggagcaggag ctaaccctga aatcggtaaa aaagctgcag aggaatctcg tgaacaaatt
    23761 gaagatgcaa tccaaggtgc agacatggta tttgttactt ctggtatggg tggcggaact
    23821 ggtactggtg cagcaccagt cgttgctaaa attgcaaaag aaatgggcgc attaactgtt
    23881 ggtgttgtaa ctcgtccatt tagttttgaa ggacgtaaac gtcaaactca agctgctgct
    23941 ggagtagaag ctatgaaagc tgcagtagat acattaatcg ttataccaaa tgaccgttta
    24001 ttagatatcg ttgacaaatc tacgccaatg atggaagcat ttaaagaagc tgataacgtg
    24061 ttacgccaag gtgtacaagg tatctcagac ttaatcgctg tttctggtga agtaaactta
    24121 gactttgcag acgttaagac aattatgtct aaccaaggtt ctgcattaat gggtattggt
    24181 gtttcttctg gtgaaaatag agcggtagaa gctgctaaaa aagcaatctc ttctccatta
    24241 cttgaaacat ctatcgttgg tgcacaaggt gtgcttatga atattactgg tggcgagtca
    24301 ttgtcattat ttgaagcaca agaggctgct gatattgtcc aagatgctgc agatgaagac
    24361 gttaatatga ttttcggtac agttattaat cctgaattac aagatgagat tgttgtaaca
    24421 gttattgcaa ctggttttga tgacaaacca acatcacatg gtcgtaaatc tggtagcact
    24481 ggattcggaa caagcgtaaa tacttctagc aatgcaactt ctaaagatga atcattcact
    24541 tcaaattcat caaatgcaca agcaactgat agtgtaagtg aaagaacgca tacaactaaa
    24601 gaagatgata ttccaagctt cattagaaat agagaagaaa gacgttcaag aagaacaaga
    24661 cgttaatcgg ttaatatata tacacaaata attcaaca
//
LOCUS       DAPDIM010000042        23910 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000042 DAPDIM010000000
VERSION     DAPDIM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 23910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23910
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.042"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            277..1149
                     /locus_tag="RFE25_001796"
     CDS             277..1149
                     /locus_tag="RFE25_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDU2816850.1"
                     /translation="MSNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASL
                     LDISTSSVIRFSKKITDGGFHDLKINISKYVPKASSIYNVELMNNESTESLRTKLHTR
                     TTRALNHANNELNDKTIDQICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQL
                     VQETHIFATLLATHNSNDSVILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVA
                     QASNIVLTYGKTDENEMHMGATTSLFAQMFTIDILYYRYVALNYHASLDFITQSKMAL
                     DNYRKHLSNINFKH"
     gene            complement(1536..2915)
                     /locus_tag="RFE25_001797"
     CDS             complement(1536..2915)
                     /locus_tag="RFE25_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDU2816851.1"
                     /translation="MENNELQRGLSARQIQMIALGGTIGVGLFMGATSTIKWTGPSVI
                     LAYLIAGIFLFLIMRAMGEMIYLNPTTGSFATFASDYIHPAAGYMTAWSNIFQWIVVG
                     MSEVIAVGEYMKFWFPELPTWIPGVIAILLLMAANLFSVKAFGEFEFWFALIKVVTII
                     LMIIAGFGLIFFGFGNGGHAVGISNLWTNGGFMPNGIVGFFFALSIVIGSYQGVELIG
                     ITAGETKDPQKNIVKAVNGVIWRILIFYLGAIFVIVSVYPWNQLGDIGSPFVATFAKI
                     GITFAAGLINFVVLTAAMSGCNSGIFSASRMIYTLAHKGEMPKIFTKIMRNGVPLYTV
                     VAVSLGILIGALLNVILPLYIDGAKSIFVYVYSASILPGMIPWFMILFSHLRFRKLHP
                     EELEGHPFKMPGGAVTNYLTILFLILVLVGMVFNVETRISVLIGVIFLTIVTIYYFIR
                     YNKNNVKAK"
     gene            3195..3551
                     /locus_tag="RFE25_001798"
     CDS             3195..3551
                     /locus_tag="RFE25_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816852.1"
                     /translation="MLKQILPRATKISILFAVAFFIINYIGMEKPDILYLVGRTIIAT
                     LAFILICLTLFTIINSPERKIKLGTTLPIALIIGIIFGAIFLTVQIGVITGLIIGVIA
                     TFIWELIEKNKGGRSS"
     gene            3548..3733
                     /locus_tag="RFE25_001799"
     CDS             3548..3733
                     /locus_tag="RFE25_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816853.1"
                     /translation="MTTALIGVIVLILLIISFVPNYRAMKSAKEQGSNATRATIMVGI
                     DIILIVLIIVTLLLKYM"
     gene            complement(3829..4020)
                     /locus_tag="RFE25_001800"
     CDS             complement(3829..4020)
                     /locus_tag="RFE25_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816854.1"
                     /translation="MMGYIILFFLAGPVILGVGNLVIGPIFNKQTPFRVQVRSFVVGS
                     MIYLILATIGYFLLLQGKL"
     gene            complement(4031..4666)
                     /locus_tag="RFE25_001801"
     CDS             complement(4031..4666)
                     /locus_tag="RFE25_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDU2816855.1"
                     /translation="MYRAVIFDFDGTIIDTEQHLFNVINKHLEMHNADPISIDFYRSS
                     IGGAATDLHDHLIKAIGSENKDKLYEEHHLTSTTLPMIDTIKSLMAFLKQRHIPMAIA
                     TSSVKAEIMPTFKALGLDDYIEVVVGREDVEQVKPDPELYLSAVQQLNYMPTQCLAIE
                     DSVNGATAAIAAGLDVIVNTNKMTSAQDFSNVDYVAKDIDYDQIVARFFTK"
     gene            complement(4741..5658)
                     /locus_tag="RFE25_001802"
     CDS             complement(4741..5658)
                     /locus_tag="RFE25_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HDU2816856.1"
                     /translation="MFQKLSIFATKSFLVWMLVAAVIGFIFPQHVATLGKWVPYLLGI
                     VMLGMGLTITPNDFKMVFKAPRAVIIGVCLQFSIMPTLAFIIAKSFHLPPDIAVGVIL
                     VGCCPGGTSSNVMSYLAKANVALSVSITTVSTLLAPFVTPALIYLFANEWLEVSFLSM
                     LWSVVQVVLIPIALGIVLQIINRKIAEKASTALPIISVVAISLILAIVVGGSKHQILT
                     TGLLIFLVVILHNVLGYTIGYWLARLLKLDRQDQKAVSIEVGMQNSGLAVSLAALHFN
                     PIAAVPGAVFSFIHNITGPILAKYWSKKL"
     gene            5926..6456
                     /locus_tag="RFE25_001803"
     CDS             5926..6456
                     /locus_tag="RFE25_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816857.1"
                     /translation="MLIDKFETYIINIAGLNDRTTRKKLSKLCKSVQFCDALQFSINK
                     QFNQYVLEISLPKQQLPYFISFLSFHQYSIFQVLSPKKINELLDSDNLYQSAKRFDIN
                     IDGLQDAFIKDKVIDIMNMFQNHTDITYTLNKSHAHIICTPEIFAKLLHTIATRNIDI
                     LSANYRSSSMSKARIS"
     gene            complement(6522..8126)
                     /locus_tag="RFE25_001804"
     CDS             complement(6522..8126)
                     /locus_tag="RFE25_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDU2816858.1"
                     /translation="MNAIKRFGSAMIVPVLMFAFFGIVLGFATLFKNPTIMGSLADQH
                     TFWFKFWSVIESGGWVIFTHMEVVFVVGLPLSLAKKAPGHAALAALMGYLMFNTFINA
                     ILTQWPHTFGANLEKGVENVPGLKSIAGIATLDTNILGGIIISAIITWIHNRYYSKRL
                     PEMVGVFQGLTFVVTISFFVMLPLAAITCVIWPTVQHGIGSMQHFIIASGYIGVWLYH
                     FLERVLIPTGLHHFIYAPIEVGPVVVNHGLKAEWLQHLNEFAKSTKPLKEQFPYGFML
                     QGNGKVFGCLGIALAMYATTPKENRKKVAALLIPATLTAVVVGITEPLEFTFLFIAPY
                     LFVLHAVLAASMDTLMYAFGVVGNMGGGLLDFISTNWLPLGKEHWGTYVAQVIIGLIF
                     VAIYFFLFRFLILKFDIPLPGRKKTEEEVKLFSKQDYKNKKGDSVDSKRASTGNEYED
                     KAAYYLDGLGGKENIKDVTNCTTRLRLTVYDESKVADTEYFTHQQMAHGLVKSGKSIQ
                     VVVGMTVPQVREAFEQMVEDQSSEDK"
     gene            8456..9220
                     /locus_tag="RFE25_001805"
     CDS             8456..9220
                     /locus_tag="RFE25_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDU2816859.1"
                     /translation="MFLDEHINRNFDKLNDNDLHIAHFINTHIDECKNMKIQDLAQFT
                     HASNATIHRFTRKLGFDGYSDFKSYLKFESNKTHQLPSNSIDSFKQEIDSTFSYLERV
                     DYQLLTEKMHTASTIYLYGTGRAQLNVASEAQRILLTLHNHVIVLHDEHELKMILNKS
                     EPNDLFFIISLSGETHELLEVTNLLQLRQKYFISVTTMKDNTLAQKANYNVYVSSNTF
                     YLTDGTDYSSFISYHIFFETLVRKYNEYLLHNDISN"
     gene            complement(9278..9784)
                     /locus_tag="RFE25_001806"
     CDS             complement(9278..9784)
                     /locus_tag="RFE25_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC domain-containing protein"
                     /protein_id="HDU2816860.1"
                     /translation="MAKFNVENEHVEVEIEKLYKFSPELVYEAWTKKDLLKQWFMTSA
                     RTNKEIEADVKEGGKYRIVDQQRNGKVNVIEGIYESLVMDEYVKMTIGMPGLSETQDV
                     IEVEFFERETGGTQMLFYYRSLVEKERRFTNLEYKQKKKEYHDAMVHGFELMFDKMYH
                     VIETSTQQ"
     gene            complement(9951..11264)
                     /locus_tag="RFE25_001807"
     CDS             complement(9951..11264)
                     /locus_tag="RFE25_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020444780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDU2816861.1"
                     /translation="MEVHKKSNAWALFPLLLFVALFLGVGIITGNFTSMPLNVAITIT
                     VIVALLMNRKESFAKKVEVFTKGAGHSNIILMMLIFILAGAFSNTAEKMGGVKSTVNL
                     GLSLIPENLIIVGLFVICMFVSISMGTSVGTVAAIAPVGYGFAQATDVPTALAMATVV
                     GGAMFGDNLSMISDTTIAAVRTQHTKMKDKFRVNFKIVLPGAILTIIILYFLTNGISL
                     NHAKNYDYNLIKVVPYILVLVLALLGVNVIIVLIGGTLLAGIIGLIDGSFGWMGLLDA
                     VSKGIISMEDIAMIALLIGGLVGIIQHNGGIEWLLQFVRSKVKSKRGAELGIASLVSV
                     ADIATANNTISIIMSGPLAKNIADEYDVDSRKSASILDIFGGCFQGLLPYSPQVISAA
                     GVAGISPLMLFPYSIYPILLGVCGLIAILFNFPKLKKNTSQEMKH"
     regulatory      complement(11341..11436)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11489..12058)
                     /locus_tag="RFE25_001808"
     CDS             complement(11489..12058)
                     /locus_tag="RFE25_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816862.1"
                     /translation="MALIVSRAILFLILALAFGIATVFPEQKLPLYIVFTLFVAVAII
                     MNVWFTHQNVKKHIIKFNKYVAYFLSFVSGLLYIGFVIYTLTIGSYDVLPIIIFAISI
                     VLVQILENILGISIKNTRLSNKQLKVISKQRVQQFKVISLILVSVSIVFIFIALMLKW
                     WLLLVISIIVLIIITVAMIVYEKYYTTPD"
     gene            complement(12545..13426)
                     /locus_tag="RFE25_001809"
     CDS             complement(12545..13426)
                     /locus_tag="RFE25_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDU2816863.1"
                     /translation="MATQDPRTKFKTTEYEKQEQEVPGLQSEMTPAPDCGETSYQGHQ
                     RLQGYKMLVTGGDSAIGRAAAIAYAKEGADVAINYLPSEEQDAQEVRQVIEESGQKAV
                     LIPGDIRDEQFNYDLVEQAYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNV
                     YPLFWTVQKALEYLKPGASITTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGP
                     KGIRVNCVAPGPFWSPLQISGGQPQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEES
                     SYTTGQVFGVSGGVQID"
     gene            complement(13537..14658)
                     /locus_tag="RFE25_001810"
     CDS             complement(13537..14658)
                     /locus_tag="RFE25_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDU2816864.1"
                     /translation="MGLKDQAVTWRRYFHQFPELSDKEFKTTQKIKDILTEHHIRILD
                     LPLMTGLVAEVGQGLSCIAVRADIDALPIQELVEQDFKSENEGVMHACGHDIHMASIL
                     ATAVKLKEIEGTLTGRVKFIFQPAEELGHGAFKIIETDALKDVQAVLGFHNDPSRSVG
                     TFAIKTGAITSAVDRFEFHIKGVGGHAAKPEQCNDPVIVLAQLINSIQSIVSRNLSAF
                     DEAVVTIGQISCGNTWNVIADHAYVQGTVRSFDPVVRKLVETRLQDIADGLAQAYNMK
                     INLNYTHLPGAVMNDEALTHKAIAVAQHVGYKVEMMEQPLTIGEDFSGYSQHFPSVFA
                     LIGSHSEYDLHHPQYKPDERILEKVPEYFVEFVKRLLHE"
     gene            complement(14934..16172)
                     /locus_tag="RFE25_001811"
     CDS             complement(14934..16172)
                     /locus_tag="RFE25_001811"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HDU2816865.1"
                     /translation="MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGK
                     IVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEIL
                     EMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLK
                     VSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETG
                     VFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEK
                     LRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNLQLVMAI
                     AALKLKLSPSEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINH
                     AEKVIKDGKVIVDNTLSFKA"
     gene            complement(16172..17833)
                     /gene="hutU"
                     /locus_tag="RFE25_001812"
     CDS             complement(16172..17833)
                     /gene="hutU"
                     /locus_tag="RFE25_001812"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HDU2816866.1"
                     /translation="MRKIQAKKGLSIECKGWEQEAVLRMLYNNLDPEVAERPEDLVVY
                     GGIGKAARNWEAFEAIEKTLRELESDETMLVQSGKPVAVFKTHEEAPRVLISNSVLVP
                     EWANWDHFNELDKKGLIMYGQMTAGSWIYIGSQGIVQGTYETFAELGNQHFNGDLAGT
                     VTLTAGLGGMGGAQPLAITMNHGVAICVDVDETRVDKRIDTKYCDVKTADLDEALKLA
                     EEAKERGEGLSIGLVGNAVDIHQAILEKGFKIDIITDQTSAHDPLNGYVPQGYSVEEA
                     KVLREKDPKKYVELSQASMAKHVELMLEFQKRGAVAFDYGNNIRQVAFNNGVKNAFDF
                     PGFVPAYIRPLFCEGKGPFRFAALSGDPKDIERADEEMRKLFPENEKLLRWLDLAEEK
                     ISYQGLPSRIAWLGYGERAKMGLALNRLVRDGEISAPIVIGRDHLDAGSVASPNRETE
                     SMKDGSDAVGDWAVLNALINTAAGGSWISFHHGGGVGMGYSLHAGMVVVADGSERAER
                     RLERVLTTDPGMGVARHVDAGYDIAIQTAKEKGIHIPMIDKAGDK"
     gene            17993..18877
                     /locus_tag="RFE25_001813"
     CDS             17993..18877
                     /locus_tag="RFE25_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDU2816867.1"
                     /translation="MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLG
                     YDLFTRSTKDIKITEKGIQFYRYASELVQQYRSTMEKMYDLSVTSEPRIKIGTLESTN
                     QWIANLIRKHHSDYPEQQYRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPL
                     YEESYILLAPKETFKNQNWVDVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETD
                     RFESAVGFVHLGLGYAIIPRFYYQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQV
                     HTFVQQCQDYLYGLLEAL"
     gene            19059..19478
                     /locus_tag="RFE25_001814"
     CDS             19059..19478
                     /locus_tag="RFE25_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FosB1/FosB3 family fosfomycin resistance
                     bacillithiol transferase"
                     /protein_id="HDU2816868.1"
                     /translation="MLKSINHICFSVRNLNDSIHFYRDILLGKLLLTGKKTAYFELAG
                     LWIALNEEKDIPRNEIHFSYTHIAFTIDDSEFKYWHQRLKDNNVNILEGRVRDIRDRQ
                     SIYFTDPDGHKLELHTGTLENRLNYYKEAKPHMTFYK"
     gene            complement(19734..20669)
                     /locus_tag="RFE25_001815"
     CDS             complement(19734..20669)
                     /locus_tag="RFE25_001815"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HDU2816869.1"
                     /translation="MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSMPS
                     GVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEEL
                     IDTQKEFAMLAAKSIANHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDT
                     RAEQQSTSGTSFRQILEEDENTDYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLSH
                     VSPTIKDMIERFVHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIP
                     SDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK"
     gene            20959..22218
                     /gene="sdpC"
                     /locus_tag="RFE25_001816"
     CDS             20959..22218
                     /gene="sdpC"
                     /locus_tag="RFE25_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease SdpC"
                     /protein_id="HDU2816870.1"
                     /translation="MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSIIGVKHFIFE
                     VTDLAPLIAAIICILVFKYKKVQLAGLKFSISLKVIERLLLALILPLIILIIGMYSFN
                     TFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVG
                     LMYSVFSANTTYGTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLI
                     FLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIAYLTTRRNLEELEPNNYLDHV
                     NDDEETNHTEAEKSSSNIKDAEKTGVATASTVGVAKNDTENTVADEPSIHEGTEKTEP
                     QHHIGNQTESNHDEDHDITSESVESAESVKQAPQSDDLTNDSNEDEIEQSLKEPATYK
                     EDRRSSVVIDAEKHIEKTEEQSSDKNK"
     gene            complement(22284..22970)
                     /locus_tag="RFE25_001817"
     CDS             complement(22284..22970)
                     /locus_tag="RFE25_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase A"
                     /protein_id="HDU2816871.1"
                     /translation="MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLI
                     KERGYNITGVCTSNKIAFLAKELGIKICEINDVDHIDLAIDGADEVDPSLNIIKGGGG
                     ALFREKVIDEMASRFVVVVDETKIVQYLGETFKLPVEVDKFNWYHILRKIESYADIKV
                     ERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVG
                     TQEGVKILEK"
     gene            23144..23797
                     /locus_tag="RFE25_001818"
     CDS             23144..23797
                     /locus_tag="RFE25_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDU2816872.1"
                     /translation="MISIHAISTGKIQDLPYSSKRPIRSALDKTKISQTTWLSSTGFT
                     GDEQAYKDHGGPHKAVCGFSKHNYALYQDDLPTLPTHAMFGENLTFDYLDESDVYFGN
                     QYRLGEALIEVSEIREPCWKIQAKYNIPDLVKRMSTSGKTGFYFRVLKQGYVSPNDQL
                     YLIQEAPIEHRLSVQQLNDLYYNDRQNQDMLRYALNNPFLSPTRRDKLQKMYNRTLK"
BASE COUNT         8033 a         4627 c         3343 g         7907 t
ORIGIN      
        1 tttaaataga tgagtacata atgtataaat tgggaatata cagtatgact tacggtaata
       61 tatcaatata ttgatatatt atttgcacat gggagtatgc tattttttat ctatacatct
      121 taaaaaaatt tacagtttta caattcaata tcattaaaca aacaacatat tcagcttatt
      181 tttcattctc ttacgttaca agttgtaaat accatcgcgt taaacaacaa tagccaacgc
      241 taataaaata tattgcgtta aagtggagtg attaatatgt caaacgtact aacagaaata
      301 gatagtcaat atccatatat gactaaaaat gaaaaaaaga tagctaaatt tatactaaat
      361 tcacctcaaa aggtgattaa aatgaggtct caagacttag caagcttatt agatattagt
      421 acatcatcag tcattcgatt cagcaagaaa attactgatg gcggttttca cgacttgaaa
      481 ataaatatat ctaaatatgt tcctaaagca tcatcaattt acaatgttga attaatgaat
      541 aacgaaagca cagaatcttt aagaactaaa ctccatacac gtactacacg cgcacttaat
      601 catgcaaata acgaattaaa tgataaaact attgatcaaa tatgtcattg tttaaaacgt
      661 tctgagacga tttttatata tggttttggc gcatcttttg tagttgctac cgacttatac
      721 caaaagttat caagaatagg tcttaatatt caacttgttc aagaaacaca tatttttgct
      781 acattattag caactcacaa ttcgaacgac agtgttattc ttattactaa caatggtacg
      841 caaagtgaaa tgcaatcaat ggttaaagtt attgatgact accatatacc tataattaca
      901 attactagta caagggataa tcccgtagca caggcatcaa atattgtttt aacttatggg
      961 aaaactgatg aaaatgagat gcatatggga gcaacaactt cattatttgc tcaaatgttc
     1021 actattgata ttttatatta tcgttatgtt gcattaaatt atcacgcatc attagatttc
     1081 ataacacaat ctaaaatggc tttagataac tatcgtaaac atttatcaaa tattaacttt
     1141 aaacattaac agtcttatat aaattcttta atcatgtcat ataataattt atgcatcatt
     1201 ttcaaagctt acatgtcttt tatcttgtat aacatacgca tatgaccaat gatttgataa
     1261 ggccattcaa tttcttatat taaaaacaaa cgcagttgat tacaggattc attccatata
     1321 tcaattgcgt ttgttatttt aataatgcta ttttttattt taaagcccac agtaaaaact
     1381 aacgataata ttgccactta taagtttttc acactacaac ttcgatttaa gctatattta
     1441 taaaaaaatg cgcctactca taacattctt tggctattta actttaataa gctagggcca
     1501 aatttgtcat aaaataagcg cacattataa tcatactatt ttgcttttac attattttta
     1561 ttatatctaa taaagtaata aatcgttaca atcgttaaga agatgacacc aattagcact
     1621 gatattctag tttcaacatt aaataccata ccaaccaata ctaatattaa gaataagatt
     1681 gttaaatagt tagttactgc gccaccaggc attttgaatg ggtgaccttc caattcttca
     1741 ggatgtaatt ttctaaaacg taagtgactg aataaaatca taaaccaagg aatcatacct
     1801 ggtaaaatag acgcactata aacgtatacg aaaatactct tcgctccatc gatatataaa
     1861 ggtaaaatta cgtttaataa agcaccaatt aaaataccaa gagatactgc tacaacagtg
     1921 tacaatggta caccatttct catgatttta gtaaatattt ttggcatttc acctttatga
     1981 gcaagtgtat aaatcatacg actcgcactg aaaatacctg agttacatcc tgacattgct
     2041 gcagttaata caacaaagtt aattaatcca gctgcaaatg taataccgat tttagcaaat
     2101 gttgcaacaa acggacttcc aatgtctcct aattgattcc aaggatacac tgaaacaata
     2161 acaaaaatag cgcctaaata gaaaattaaa attctccaga taacaccatt cactgcttta
     2221 acgatatttt tctgaggatc tttagtttca cctgccgtaa tacctatcag ttccacacct
     2281 tggtatgaac caattacaat tgataatgca aagaagaaac caacaatacc atttggcata
     2341 aatccgccat ttgtccatag attagaaata cctaccgcat ggccaccatt tccaaaacca
     2401 aagaaaataa gaccaaaacc agcaataatc attaaaataa ttgttacaac tttaattaaa
     2461 gcaaaccaaa attcaaattc tccaaacgct tttaccgaga ataaattcgc tgccattaat
     2521 aataaaatag caataacacc aggaatccaa gttggcaatt ccgggaacca aaacttcata
     2581 tattctccta ctgcgatgac ctcactcata ccaactacaa tccattggaa tatattactc
     2641 catgctgtca tataacctgc tgcaggatgt atataatcac ttgcaaatgt tgcaaatgat
     2701 cctgttgtag ggtttaaata aatcatttcc cccattgctc tcatgattaa aaataaaaag
     2761 atacccgcaa ttaaatatgc aaggataact gatgggcctg tccatttaat tgtacttgtg
     2821 gcacccatga aaagccccac gccaatcgta ccaccaagtg caatcatttg aatttgacgg
     2881 gcactcaatc ccctttgtag ttcattgttc tccataactt cttaccccat ctctgattga
     2941 tactaaataa atccataaaa aaacttattg ccgtaattat actataaatt atcgattttg
     3001 gtacattaat atttgcatac catgcaatcg tttacagaac tactatagca ggcttttgca
     3061 actttgcaaa caattatttt gtgatttttc taaaaaatta aaaaagttgc tcaagtaccg
     3121 ttgagtcaca tacaacttca gctattctcg gtaattatga tataatttta ataatattaa
     3181 aaaggagtat atcaatgtta aaacaaatac tgccacgtgc tacaaaaata tcgatactct
     3241 ttgctgtagc atttttcatc ataaattata tcggtatgga aaaacctgac atcctatatt
     3301 tagttggaag aactattatt gcaacacttg ctttcatact catttgtctt acattattta
     3361 ctattattaa ttctccagag cgcaagatta aactcggtac gactttaccg attgcattaa
     3421 ttattggtat cattttcggc gccatatttt taacggtaca aatcggtgtc atcactgggt
     3481 taatcatcgg tgtgattgct acgtttattt gggaattgat tgaaaaaaat aaaggaggtc
     3541 gttcatcatg acaacagcat taattggtgt aattgtatta atcttactaa ttattagctt
     3601 tgtgccaaac taccgtgcta tgaaatcagc aaaagaacaa ggaagtaatg caacaagagc
     3661 tacaattatg gtaggcatag atattatctt aattgtactt atcatcgtga cattattatt
     3721 aaaatatatg taactattta aaccccccta tctcatacat aaacatgaac gttctgccat
     3781 ttcacataca tatggtcgtc catttaatga ggtaaggtgg ttttctcgtt aaagtttacc
     3841 ttgtaatagt aaaaaatagc caattgttgc gagtattaag taaatcattg aaccaacaac
     3901 aaaagatctt acttgcacgc gaaatggtgt ctgtttgtta aatataggac caatcaccaa
     3961 atttccaacg cctaaaatta ctggaccagc tagaaaaaac aatataatgt aacccatcat
     4021 gatacgcctc ctatttcgta aagaaacgcg ctacaatttg atcgtaatca atatcttttg
     4081 ctacataatc tacattagaa aagtcctgtg cgcttgtcat tttattcgta ttaacaataa
     4141 catctaatcc agctgcaatc gcggctgttg caccatttac agaatcttca atagccaaac
     4201 attgtgtcgg catataattt aattgttgta ctgcagataa atataattca gggtcaggtt
     4261 taacttgttc aacatcttct ctaccaacaa ctacctctat ataatcgtct agacctaatg
     4321 ctttaaaggt gggcattatt tccgctttca cactacttgt ggcaattgcc ataggaatgt
     4381 gacgttgctt taaaaatgcc atcaatgatt taatcgtatc aatcatcggt aatgttgtac
     4441 tagtaagatg atgttcttca taaagtttat ctttattttc cgaaccaatc gctttaatta
     4501 aatggtcatg caaatctgta gctgctcctc caatagaaga acgataaaaa tcaatgctta
     4561 taggatcggc attatgcatc tctaaatgtt tattaataac attaaataaa tgttgttccg
     4621 tatctattat tgttccatcg aaatcaaata taactgctct atacatatat ttactcctct
     4681 attttttctc tttatcaaag cttaacatag tccgatgacc acttcattct attagtgcaa
     4741 ttataacttt tttgaccaat actttgctaa aataggccct gttatattat gaatgaaact
     4801 aaacactgcg cctggtactg ctgcaattgg attaaaatgc aatgctgcta atgacacagc
     4861 taaaccagag ttctgcattc caacttcaat actgactgct ttttgatctt gtcgatctaa
     4921 ttttaaaaga cgagctaacc aatatccaat cgtataccct aatacgttat gtaaaataac
     4981 tactaaaaat attaataatc ctgtagttaa gatttggtgc ttactgccac ctacaactat
     5041 tgctaaaatt aatgaaatag caacaactga tataatcggc aaagctgtag aagctttttc
     5101 agcaatttta cgattaataa tttgcaaaac aatacctaaa gcaattggaa ttaatacaac
     5161 ttgaacaact gaccacaaca tactcaggaa agatacttcc aaccattcat ttgcaaatag
     5221 atatattaac gcaggtgtaa cgaatggcgc tagcaacgta gagaccgtcg taatagaaac
     5281 agaaagtgct acgttagctt tggctaaata actcattaca ttacttgatg tcccacccgg
     5341 acaacatcca actaatatta cgccaacagc aatatcaggt ggtaaatgaa aagactttgc
     5401 aattataaat gctaatgtgg gcataatact gaattgtaga cagacaccaa taattactgc
     5461 tctaggtgct ttaaagacca ttttgaaatc attaggtgta attgttaatc ccatacctaa
     5521 cataacaata ccaagtaaat aaggtaccca cttacctaat gtcgcaacat gttgtgggaa
     5581 aataaatcca ataacagctg ctactaacat ccataccaaa aaactcttcg tggcaaatat
     5641 actcaatttt tgaaacattg ttaacacatc ctcgtcgata atattgaaaa atattaccat
     5701 aagaccagta aggttacaat tacttttctg aaaattaaga ttatttagcc attctcttct
     5761 tattgcaaat attttatcac tgataaacaa ttattttaaa cttcattcaa aagtcttagt
     5821 gaataaagaa aaaaagcgtg gtaaaatcaa cttgaacaaa attaagtcac ctttataaat
     5881 attaaacgtg tatttaatgc catgtattcc tcgggaggtc ctcacatgtt aattgataaa
     5941 ttcgaaacat acatcatcaa catcgccggt ttaaatgacc gtactactag aaaaaaatta
     6001 agtaagttat gcaaaagtgt acaattttgt gatgcgttgc aattctcaat aaacaaacag
     6061 tttaatcagt atgtattaga aattagctta ccaaagcaac aacttccata cttcatttca
     6121 tttttaagtt ttcatcagta tagtattttc caagtacttt caccaaagaa aataaatgaa
     6181 ttacttgatt ctgataattt atatcaatct gcaaagcgtt tcgatatcaa tattgatggc
     6241 ttgcaagatg ctttcattaa agacaaagtc atcgatatta tgaatatgtt ccaaaatcac
     6301 actgatatca cttatacgtt gaataagtct catgcacata ttatatgtac gccagaaata
     6361 tttgctaaat tgttacatac gattgcaact agaaatatcg acattctatc tgccaattat
     6421 agatcgtcat ctatgagcaa agctcgtata tcataataaa agacacatct atacgatgat
     6481 catttacaat gattgcgtat agtgatgtgt ctttttttgt attatttatc ttcggacgat
     6541 tgatcctcaa ccatttgttc aaatgcttca cgaacttgtg gtactgtcat acctactaca
     6601 acttggatac tcttaccact ctttactaat ccgtgtgcca tttgttgatg cgtgaaatat
     6661 tccgtatccg caactttact ttcatcataa acagttaagc gtaatcttgt tgtacagtta
     6721 gtaacatctt tgatattttc tttgccgcct aaaccgtcga ggtaatacgc agctttgtct
     6781 tcgtattcat tacctgttga agcacgttta gaatctacgc tatcaccttt tttatttttg
     6841 taatcttgct tagaaaataa tttaacttcc tcttctgttt tcttacgtcc aggtaatgga
     6901 atatcaaatt tcaaaattaa gaatctgaat aagaagaagt aaatcgctac aaatatcaga
     6961 ccgataataa cttgtgcaac ataagtaccc caatgttctt tacctaatgg caaccagttt
     7021 gttgaaataa agtctaacaa gccaccaccc atgttaccta caacaccaaa tgcgtacatt
     7081 aaagtatcca ttgatgctgc taaaactgcg tgtaaaacaa ataagtatgg tgcgatgaat
     7141 aagaatgtaa attctaatgg ctcagtaata cctacaacga ctgctgttaa tgttgcagga
     7201 ataagtaatg ctgctacttt tttacgattt tctttaggtg tcgtagcata cattgctaaa
     7261 gcaataccta gacatccaaa tactttccca tttccttgaa gcataaagcc ataagggaat
     7321 tgctctttta atggcttagt actcttagca aactcattta aatgttgtaa ccattcagct
     7381 ttcaagccat gattgactac tactggtcca acttcaattg gtgcataaat aaagtgatgt
     7441 aatcctgttg gtattaatac acgttctaag aagtggtaca gccaaacacc gatatagcct
     7501 gaagcgatga taaagtgttg cattgaacca ataccgtgct gaacagttgg ccaaataaca
     7561 caagtaattg ctgctaatgg taacatcaca aaaaatgaaa ttgtaaccac aaatgttaaa
     7621 ccttggaata caccaaccat ttctggtaat cgtttactgt agtatctatt gtgaatccac
     7681 gtaataatag ctgaaataat aataccacct agaatattcg tatccaatgt ggcaatacct
     7741 gcaattgatt ttaaaccagg tacattttca acgccttttt ctaaattagc gccaaatgta
     7801 tgtggccatt gcgttaaaat ggcatttata aatgtattaa acattaagta acccatcaat
     7861 gctgcaagcg ctgcatgacc tggtgctttt ttagctaaag aaagtggtaa acctacaaca
     7921 aatacaactt ccatatgcgt aaaaataacc cagccaccag attctatcac tgaccaaaat
     7981 ttaaaccaaa acgtatgttg atctgctaaa ctccccatga ttgtaggatt tttaaataat
     8041 gtcgcaaagc caagcactat cccaaagaaa gcgaacatta ataccggtac aatcattgca
     8101 ctaccgaaac gctttatcgc attcatcttc tattccctcc atatcatctt tcctaacaat
     8161 acatctaatt agattcattt ataaatagat gtcttactat ttaaatataa tatatagtaa
     8221 acgcttacac acctacaacg acattgacgt attttgaaag tattttgtat aatcagatta
     8281 tcttttcata tagtgaaaat tttttcacga ccttatatat gacatcgttg tatttgtaat
     8341 acattcgttt taaacgcata atcaaaccta tatcaataca caaatatata taatgacata
     8401 caagatttta atgtaataac gatctatcac acatttattt tcaaggaggt tgaatatgtt
     8461 tttagatgaa cacattaatc gaaactttga taaacttaat gataatgatt tacatatcgc
     8521 tcactttatc aatacacata tagatgaatg taaaaatatg aaaatacaag atttagcgca
     8581 attcacacat gcctcgaatg caaccattca cagatttaca cgcaaattag gttttgacgg
     8641 ttatagtgat tttaaatcgt accttaaatt tgaaagtaat aagacacacc aattaccttc
     8701 taactctatc gatagtttca aacaagaaat cgatagtaca ttcagttatt tagaacgcgt
     8761 tgattaccag cttcttactg aaaaaatgca tacagcttca acaatatatt tgtatggtac
     8821 agggcgtgca cagttaaacg ttgcttcaga ggcacagcgt atattgttaa cgttacataa
     8881 tcatgtcatt gtacttcatg atgaacatga acttaaaatg attttgaaca agagtgaacc
     8941 taatgattta ttctttatta tttcattatc aggtgaaaca catgaattat tagaagtaac
     9001 aaacttgctt caacttagac aaaaatactt tatttctgtt actacaatga aagataatac
     9061 ccttgctcaa aaagcaaatt acaacgtcta tgtatccagt aacacattct acttaactga
     9121 tggtacagac tattctagct tcatcagtta tcatatattc tttgaaacac ttgtaagaaa
     9181 atataatgag tatttactac ataatgatat ttcaaattag aaaaaaggaa gttatgattt
     9241 aatggccttg agcctatcat aacttccttt tatcatttta ttgttgtgtt gatgtttcga
     9301 taacgtggta catcttatca aacatcaatt cgaaaccatg caccatggca tcatgatatt
     9361 cttttttctt ttgcttgtat tctaaattag taaatcgtct ttctttttca actaatgaac
     9421 gataataaaa tagcatttgg gtgccacctg tttcacgttc aaaaaattct acctcaatga
     9481 catcttgtgt ttcacttagt ccaggcatac cgatagtcat cttaacgtat tcatccataa
     9541 ctaaagattc ataaatgcct tcaatcacat ttactttgcc attacgttgt tgatctacaa
     9601 tacgatattt accgccttct ttaacgtccg cttcaatctc tttattcgtt ctggctgatg
     9661 tcataaacca ttgtttcaac aaatctttct ttgtccaagc ttcgtatact aactctggag
     9721 aaaatttata aagcttttca atttcaactt cgacatgttc attctctaca ttaaattttg
     9781 ccactgttgt ccacccactt tcgctcttac ttttatttta acgtattttt gctcagttcc
     9841 aaacatagat gatcatcatt tttaaaagat tagcgttata cggtgagtac aacatgatct
     9901 gttaatataa caagccacct tacttggcta catcgatata ttgttaagca ttaatgtttc
     9961 atttcttgac tagtgttctt ttttagcttt ggaaaattaa ataaaatcgc aataagtccg
    10021 catacaccta ataatatagg ataaatgctg tatgggaata acattaatgg tgaaatacca
    10081 gctacaccag ccgctgaaat gacttgcggg ctatatggta ataaaccttg gaagcagcct
    10141 ccaaatatat caagaatact tgctgatttc cttgaatcta catcatattc atctgcaata
    10201 tttttagcta aaggacctga cataataata gagatggtgt tgtttgccgt ggcaatatct
    10261 gcgacactta ccaaactcgc aattcctaat tctgcgccac gctttgattt cactttagag
    10321 cgaacaaatt gcaacaacca ttcaatacca ccattgtgtt gaataatacc gactaaacca
    10381 ccaattagca acgcaatcat agcaatatct tccatgctta taataccttt ggacactgca
    10441 tctagtagtc ccatccaacc gaatgaacca tctatgagac caatgattcc agctaataat
    10501 gttccgccaa tcaatacgat aatgacattt acacctaata atgctaatac caatactaaa
    10561 atatacggta caactttaat tagattataa tcatagtttt tagcatgatt taaagaaatg
    10621 ccattcgtta agaaatacag aataataatc gttaaaatag cacctggcaa tacaatttta
    10681 aagtttactc tgaatttatc tttcattttc gtatgttgtg ttctaaccgc agcaattgtt
    10741 gtatctgaaa tcattgatag attatcgccg aacattgcac ctccaacaac tgtagccatt
    10801 gctagcgcag ttggtacatc tgtcgcttgt gcaaatccgt aaccaacagg tgctattgca
    10861 gcaacagttc ctacagacgt ccccatagat atagaaacaa acatacaaat cacaaacaat
    10921 cctacaataa ttaaattttc tgggattaat gatagtccta aattaactgt cgactttacg
    10981 ccacccattt tttcagctgt atttgaaaat gcacctgcta aaataaaaat caacatcatt
    11041 aaaataatgt ttgaatggcc tgcacctttc gtgaagacct caactttttt agcaaatgat
    11101 tcttttcgat tcattaataa cgccacaatt accgttatcg taattgcaac atttaatggc
    11161 attgaagtaa aattacctgt gataatacct acgcctaaaa acaacgccac aaataataac
    11221 aaggggaata atgcccaagc attgctcttt ttatgtactt ccatcctttt tacctgcttt
    11281 ccaattaaaa atacctcttt ctcacaaacg atgaagaaag aggttttcat gtgctttacc
    11341 tgcttatctt caaaccatta cggttactgg aattggcaca ttcgagatgt tgccgaggct
    11401 tcatagggcc agtccctcca cctctctaga taagtgatgc ttatttacgt ttacgttaca
    11461 agataatcct tagtacgtca atcataaatt aatcaggagt cgtataatat ttttcataaa
    11521 caatcattgc tactgtaata ataatcaaaa caataatgct aataacaagt aaaagccacc
    11581 atttaagcat taatgcaata aaaatgaaca cgatagacac acttactaat attaatgata
    11641 tgactttaaa ttgctgaaca cgttgcttgg agatgacttt caactgtttg tttgatagac
    11701 gcgtattttt tatactgatt cccagtatat tttctaatat ttgaaccaat acgatactta
    11761 ttgcaaatat aataattggt aaaacatcat agctccctat agttaatgta taaattacaa
    11821 atccaatgta aagtaaccct gagacaaagg ataaaaagta tgcgacgtat ttgttaaact
    11881 taatgatatg ctttttaacg ttttgatggg taaaccatac attcataata atcgcaactg
    11941 ctacaaataa tgtgaatact atatataatg gtaatttttg ttcaggaaaa acagtcgcta
    12001 ttccaaaagc taatgctaaa atcaaaaata atatagctct agatactatt aatgccataa
    12061 taacaacccc tttgtttaat atcgagtttg caaatttacg tttatcagca tttctatgat
    12121 cagtacttct acgggtagcg tttctatgta atttacatca tcttaacata taaatacttc
    12181 gctatttaat tgaaaacata tcttattatt ctttgtccgt tctgacattt aatatctaac
    12241 cttaggcatt tcacttgtta ataaatttaa ctttcttcca ctaaccgtcc ctaaacccaa
    12301 tcccgcaaca gtttttaact ttttcgttgt tgtcctgaca tcctcattaa gaaagtttat
    12361 tctgcttaaa acttataatc cacaccctga gcaaacgctc cttatgacag agtattaaaa
    12421 taagccgata aagatacaca cctttaccga ctatttaaaa tacacttcac caattcattt
    12481 taatttaatg gattgaagta actaaattaa tattatgctg ttcaattaaa agcttcatac
    12541 aaccctaatc tatttgcact ccaccgctaa caccgaacac ttgtccagtt gtataacttg
    12601 attcctctga cgctaatagc acataagttc cacataactc aacaggttga cctgcacgac
    12661 ctaaaggtgt tttttgacca aatgttggga ttttactttg aggttgccca ccagaaattt
    12721 gtaatggtga ccagaatgga ccaggtgcta cacagttcac tctaattcct tttggtccta
    12781 attcttctga aaaactttta gttaatgaaa taattgctgc ttttgaagcg gcataatcat
    12841 gaagaatagg actaggatta taaccttgta cagatgatgt cgttgtaatt gacgcacccg
    12901 gttttaaata ttccaatgct ttttgaactg tccaaaatag cggatagaca ttcgtttcaa
    12961 atgtttctgt aaatgcctca gttgtaaatc catgaatatc atcatgatac tgttgatgtc
    13021 cagcaactaa agtaacatta tctaagccac ctaattgttg atatgcttgt tcaacaaggt
    13081 catagttgaa ctgctcatct cttatatcac caggaattaa cactgccttt tgaccacttt
    13141 cttcaattac ttggcgtact tcttgtgcat cttgttcttc actcggaaga tagttaatcg
    13201 ctacatctgc accttcttta gcatacgcaa ttgctgctgc acgccctatt gctgagtcac
    13261 cacctgtgac taacatttta tagccttgta agcgttgatg accttggtaa gacgtttcgc
    13321 cacaatcagg tgctggcgtc atttcagatt gtaaacccgg tacctcttgt tcttgttttt
    13381 catattccgt tgttttaaat tttgttctag gatcttgagt tgccattttt taacatctcc
    13441 ttattcgctt aatggttatt atttacccaa tcttcctagg aacttaatca tgattacact
    13501 aaaaattact ttcttcttta taaaaacaag ctcgaattac tcatgcaata gtctctttac
    13561 aaattcaaca aaatactcag gtactttttc cagaatcctt tcatccggtt tatattgagg
    13621 gtgatgtaaa tcatattcac tatgagaacc aattaacgca aatacacttg gaaaatgttg
    13681 actataacct gaaaaatctt ctccaatcgt aagcggctgt tccatcattt ccaccttata
    13741 tccaacatgt tgggctactg caattgcttt atgcgtcaat gcctcatcat tcatcacagc
    13801 gccaggtaaa tgtgtataat ttaaattaat tttcatatta tatgcttgag ccaatccgtc
    13861 cgcaatatct tgtaatcgtg tttctacaag ctttcgtacc acaggatcaa aactacgcac
    13921 tgtgccttgt acatacgcat gatcagcaat gacattccaa gtattaccac atgatatttg
    13981 tccaattgtt actaccgctt catcaaacgc agatagattt ctactaacta tggattgaat
    14041 actattaatc aattgcgcca acacaataac tggatcgttg cattgttctg gctttgcagc
    14101 atgaccaccc acgcctttaa tatgaaactc aaagcgatct actgctgatg taattgcccc
    14161 tgttttgatt gcaaatgtac ctaccgaacg cgatgggtca ttatgaaaac ccaatactgc
    14221 ttgtacatct tttaatgcat ctgtttcaat aattttaaaa gcgccatgtc ctagttcttc
    14281 tgctggttga aaaatgaatt taacacgccc agtaagagtg ccctcaattt cttttaattt
    14341 tacagccgta gccaaaatac tagccatgtg aatatcatga ccgcacgcat gcataacacc
    14401 ttcattttca gatttaaaat cctgttcaac aagctcttga atcggtaaag catcaatgtc
    14461 agcccgaaca gctatacaac tcagaccttg tcccacttca gcaaccagcc cagtcataag
    14521 cggtaagtct aatattctaa tatgatgttc tgttaaaata tctttaattt tttgtgtagt
    14581 cttaaattct ttatcggata gttctggaaa ttgatgaaaa taccttctcc aggtaacagc
    14641 ttgatctttt aatcccatcg gtcattcccc ttccttaagt caatgatatg ttgtctaccc
    14701 tacgatgatc atctttgact attaaacgat gatttcacaa caatgtactc ttgttaatta
    14761 ctttcgctaa tgatagacag ttgtttaata atatcgtaac actgttgtca aactattcta
    14821 acttttataa ttaagaatct atacaaaaac gtgttctcgg ataaacttgt ttttacaaac
    14881 cacaaaagct ctaaacatta gtgtaaacca atgcttagag ctttctaatt attttatgct
    14941 ttaaaagata atgtgttatc tacgatgacc ttaccgtctt taataacttt ttctgcgtga
    15001 ttgataccaa aatgatatgg aatatattca tgatttggtg catcccaaat tactaaatta
    15061 gccttatcac ctgtgttaat tgtacccgcg ttaatatcta ttgctttagc agcgttgacc
    15121 gtaacagcat tccacacttc actaggcgaa agctttaatt ttaatgctgc aatggccata
    15181 acaagttgca agttattcgt tacactgctg cctggattat aatcagtagc taacgcgatg
    15241 gcaccattat tatcaagcat acctctcgca tctgcataat cttctttacc taaatagaac
    15301 gtcgttgcag gtaagaggac agctacagta tcactatttc gcaacttttc ttttccttta
    15361 tcactagaag ctactaagtg gtctgctgat attgcttgtt catcaattgc taattccagt
    15421 ccgcctaacg gatcaatttc atccgcatgt attttcactt taaaacctgc ttctttggct
    15481 ttttgcatat aatgttgcga ttgttctatt gtaaatacac ctgtttcaca gaaaatatcc
    15541 gcaaagtctg catattgttt tacttccgga agtaacgcaa tcatttcttc taaaaatgcc
    15601 tcatttgaac ttgcctcttt aggtacagca tgaggcccta ggaaagtatg tttcatgtct
    15661 aaatcatatt tctcagctaa acgattagac actttcaatt gcttcagttc attttctcta
    15721 tctaatccat aaccactctt actttcaact gcaagcacgc cgtgtttaat catagtaagc
    15781 aaatcatgct ctgctttttt aaacaagtca tcttcggatg tttctctagt agcattaacg
    15841 gtagataata tgccaccacc catttctaat atttcaaggt aagacttacc ttgacgtttt
    15901 aatgacatct catgttctcg agatccacca aatgttaaat gggtatgagc atctactaat
    15961 gccggagaaa ctacttttcc actagcatct atcgtctcag tcgcatcata gtcatctgta
    16021 tgttgtccag catatacaat tttgccatct ttaatgacaa ctgtaccatt tttcacaaca
    16081 tttaattcat ctaattcctt acccttcaaa ggtttatctg ttgatttcgg taaaattaat
    16141 tctgctatgt gattaattat taaatcattc attatttatc acctgcttta tcaatcattg
    16201 gaatatgaat acctttttct ttagctgttt gaatagcgat gtcatagcca gcatcaacat
    16261 gtcgggcaac acccatacct ggatcagtcg tcaatacacg ttccaatctt ctttcagcac
    16321 gctctgatcc atctgctaca acaaccatac ccgcatgaag tgaatatccc atgccaacac
    16381 cgccaccgtg atggaatgaa atccatgaac cacctgcagc tgtgttaatg agtgcattca
    16441 atacagccca atcaccaacc gcgtcactgc catctttcat actttctgtt tcacggttag
    16501 gactagcaac tgaaccagca tctaaatggt ctcgtccaat aacaattggt gctgaaattt
    16561 caccgtcacg tacaagacga tttaaagcta agcccatttt cgctctttct ccatagccta
    16621 accaagcaat acgtgatggt agtccttgat atgaaatttt ttcttcagct aaatcaagcc
    16681 atcttaataa cttttcattt tctgggaaaa gtttgcgcat ttcttcatcc gcacgctcga
    16741 tatcttttgg atcaccactc aacgcagcaa agcggaatgg ccctttacct tcacagaata
    16801 atggtctaat gtaagctggt acaaagcctg ggaagtcaaa agcatttttc actccgttat
    16861 tgaaggctac ttgacgaata ttgttaccat aatcaaatgc tacagcgcca cgtttttgga
    16921 attcaagcat taattcaaca tgctttgcca ttgaagcttg tgacagttca acatattttt
    16981 tcggatcttt ttcacgcaat actttcgctt cttctacaga gtatccttgt ggcacatatc
    17041 catttagcgg atcatgtgca cttgtttggt cagtaataat gtcaatttta aatccttttt
    17101 ctagaatcgc ttgatggatg tctacagcat ttccaactaa cccgattgat aatccttctc
    17161 cacgttcttt cgcctcttct gctaatttta atgcttcatc taaatcagct gttttaacat
    17221 cacagtattt cgtatcaatt cgcttatcaa cacgtgtttc atcaacatcc acgcaaattg
    17281 ctaccccatg attcatagta attgctaacg gttgcgcacc acccatacca cctaaacctg
    17341 ctgtcagtgt aacagtgcct gctaaatctc cattaaagtg ttgattacct agctcggcaa
    17401 atgtctcata agtaccttgc acaatacctt gagaaccaat atatatccaa ctaccggctg
    17461 tcatctgtcc atacatgatt aaaccttttt tatctaattc attaaaatga tcccagtttg
    17521 cccattcagg cactaatact gaatttgaaa ttaatacacg tggcgcttct tcatgtgttt
    17581 taaatacagc aactggcttt cctgattgta ctaacattgt ctcatctgat tctaattctc
    17641 gtaacgtttt ctctattgct tcaaaagctt cccaattacg tgctgctttt ccaataccac
    17701 cataaacaac taaatcttct ggtctttcag caacttctgg gtctaaattg ttgtataaca
    17761 ttctaagtac tgcttcttgt tcccaacctt tacactcaat actcaaacct ttttttgctt
    17821 gaatttttct cataaaattc gctcctgttc ttttaagaag ttaattccac taaatttaaa
    17881 acgcttacat tattatcttc aatattcatt atagtatgtt aaaatatagc caacaaatat
    17941 aaataaacta attatccata gcttgaacct ataaataaaa ggagcaaaac acatgaaaat
    18001 tattcagtta gaatacttct tggctatcgt gaaatataat agttttacta aagctgcaca
    18061 atttttacat attagccagc catctttaac tgctacgatt aaaaaaatgg aagcagattt
    18121 aggttatgac ttatttacac gttcaacaaa agacatcaag attaccgaaa aaggaataca
    18181 gttttatcgt tatgcgagcg aattagttca acaatatcga tccacgatgg aaaaaatgta
    18241 tgatttaagc gttacatcag aaccaaggat aaaaattggg actcttgaat ctacgaatca
    18301 atggattgcg aatttaattc gaaagcacca ttccgactac cctgaacagc aatatcgttt
    18361 atatgaaata catgacaaac atcaatctat agagcaatta ctgaatttta atattcattt
    18421 agctataaca aatgaaaaaa taacccacga agatataaga tccattcctt tatatgagga
    18481 atcttacatt ttattagcac ccaaggaaac atttaaaaat caaaattggg tagatgttga
    18541 aaatttgcca ctcatattac caaacaaaaa ttctcaagtg cgcaaacact tagatgacta
    18601 ttttaataga agaaatattc gtccaaatgt cgttgtagaa acagatcgat tcgaatcagc
    18661 agttggattt gttcatctcg gcttaggtta cgctatcatt ccgagatttt attaccaatc
    18721 atttcacacg tctaatttag aatataaaaa aattcgtcca aacttaggcc gaaaaattta
    18781 tatcaattac cataaaaaac gcaaacactc cgaacaagta catacattcg tacaacaatg
    18841 ccaagattat ttatatggac ttttagaggc tctttaactt aagttattag agcctcttat
    18901 gcagttgctc agtcaactgt ataccttttt cctttaactt aagttattag agcctcttat
    18961 gcagttgctc agatcatcgt ataaaaatta atgacgtcat ttcaaaaatc gatacaaaaa
    19021 taatttatta taaaaattct aagaaagaag tgaagcagat gttaaaatct attaatcata
    19081 tatgcttttc agtcagaaat ttaaacgatt caatacattt ttatagagat attttacttg
    19141 ggaaattgct attgactggt aaaaaaactg cttattttga gcttgcaggc ctatggattg
    19201 ctttaaatga agaaaaagat ataccacgta atgaaattca cttttcatat acacatatag
    19261 ctttcactat agatgacagc gaatttaaat attggcatca gaggttaaaa gataataacg
    19321 tgaatatttt agaaggaaga gttagagata ttagagatag acaatcaatt tactttactg
    19381 accctgatgg tcataagcta gaattacata ctggcacact tgagaacaga ttaaattatt
    19441 ataaagaggc taaaccacat atgacatttt acaaataagg cgtcattata aaaaggcctc
    19501 ttgaaatccg ttaaaatttt aattaattat tatataataa gagaactttt caaacaatac
    19561 agttgttatt tttgctattt caacaaacat aaataagcag taagatgact acaacttaag
    19621 agtcttctta ctgcaattat ttttcaaata tatcaacgtt aatataactt ctattaagaa
    19681 atactcacat tctgccctgc aatgcaaatc tcgtcacata taaatatttt taattatttt
    19741 aaaaaatgat gcactaaatt agcaacgagc ttagcagttc tattgtcagc gtcatatgtt
    19801 ggattcatct cagcaatact aactgaagac accttatcac ttggaataat acgttttgct
    19861 aattcaagaa cagtatgtgg atacaaacct aacactgccg gcgcacttac cccaggcgca
    19921 aacgcactat caatgacatc catacaaatc gtaaacataa tgacatcatg ttcatgtaca
    19981 aaacgttcaa tcatatcttt aattgttggt gatacgtgac tcaataattc atctgcaaag
    20041 acataatcaa tctttttctc tttagcataa tcaaataaac tttgcgtatt accaccttga
    20101 gcaataccaa gcactaaata atctgtgttt tcatcttctt ctaaaatttg tctaaagctc
    20161 gttccagatg tagattgttg ttcagcacgt gtatcaaaat gcgcatcaat atttatcaca
    20221 ccaatagatt gtgttggata gactttacgt gttgctaaat attgagcata cgcaatatca
    20281 tgtccaccac ctaataaaaa tgtttgtcta tgattagcaa ttgacttcgc tgcaagcata
    20341 gcaaattctt tttgagtatc aattaattcc tcatgatcat gataaacatt tccgtaatcg
    20401 actaaagttt cacattgatt caaatccggc aaacctgcaa atgcttgttt aatcgcatct
    20461 ggtccttctt ttgcaccaat gcgccccttg tttaaagcaa cacctttgtc aacagcatag
    20521 cctaatatac cgacccctga tggcatacta ctcttttcca gcttagacaa atcttcaaat
    20581 gttactgttt gaaaatgtct aaattttttc gggtctgttt cactatctaa ccttccagtc
    20641 cataaatttg gttcaccttg cttgtacaca gcatttcccc ctcttattta tgtggcttat
    20701 taacaattaa agtataacgt ataggaaatt ttgaattcaa ttcatagtta aatccgtatc
    20761 ttaaaaatac ttatctacat tacttttacc cctattttct atgtaataac gaatacttag
    20821 ctgatttatg ttaataaaat acgtcaagac tattacattt tcattaatat tgacatagac
    20881 aatttatctc tcggcttgta atatgtataa ttgttactaa aagatatttt gcttgttacc
    20941 taatggaggt tacatataat gaagaacaat aaaatttctg gttttcaatg ggcaatgacg
    21001 attttcgtct tctttgtcat tacaatggcg ttatccatta tgctcagaga tttccagtct
    21061 ataattggtg tcaaacactt tatatttgaa gttacagatc tagcaccatt aattgctgca
    21121 atcatttgta tactcgtttt caaatataaa aaggtccaac ttgcaggttt aaaattctca
    21181 atcagcctga aagtaattga acgtctattg ctagctttaa ttttaccttt aattattcta
    21241 attattggta tgtacagctt taatacattt gcagatagct ttattttatt acaatcaaca
    21301 ggcttatcag tacctattac acacattctg attggacata ttctgatggc gttcgtagta
    21361 gaattcggat tccgttcata cttacaaaat attgttgaaa cgaaaatgaa cacgttcttt
    21421 gcaagtattg ttgttggttt gatgtattca gttttctcag caaatacaac ttatggtaca
    21481 gaatttgctg cttataactt cctttataca ttctcattct ctatgattct tggtgaatta
    21541 attagagcga ctaaaggacg tacaatttat attgcaacga cattccatgc ttcaatgaca
    21601 ttcggactta ttttcttgtt tagcgaagaa atcggcgatc tattttcaat caaagtcatc
    21661 gccatttcaa cagcaatcgt tgcagtagga tacattggtt taagcttaat tatccgaggt
    21721 attgcatatt taacaacaag acgaaacctt gaagaacttg agcctaataa ttatttagac
    21781 catgtcaatg acgatgaaga aactaatcat actgaggctg aaaaatcttc ttcaaatatt
    21841 aaagatgctg aaaaaacagg tgtagctact gcatcaacgg ttggtgttgc taaaaatgat
    21901 actgaaaata cagtggctga cgaaccaagc attcatgaag gtactgaaaa aacagaacct
    21961 caacatcaca taggtaatca aactgaatct aatcatgatg aagatcatga catcacttcg
    22021 gagtcagtag aatcagcaga atcagttaaa caagcaccac aaagtgacga tttaacaaac
    22081 gattcaaatg aagatgaaat agagcaatca ttaaaagaac ctgcgactta taaagaagac
    22141 agacgttcat cagttgtaat tgatgcagaa aaacatatcg aaaaaactga agaacaatct
    22201 tcagataaaa acaaataata acaaagcgct tgctagtacc tcttaaaaag atgatgctag
    22261 caagcgcttt tctatactat atattatttt tctaaaattt taacaccctc ttgagtgcct
    22321 acaataactt gatctgccat atctaagaag tatcctgtct caaacacacc tgtcagatga
    22381 attaaatact catggaactt atatgggtca attccttttg gtaacttaca atctaaaata
    22441 taattgccat tatcagttat aaatgcgaca tcttcgttta cacgacgttc tacttttata
    22501 tcagcgtatg attcaatttt acgtaatatg tgataccagt taaatttatc cacctctact
    22561 ggtaacttaa acgtctcacc taagtattga actattttcg tttcatcgac aaccacaaca
    22621 aaacgcgatg ccatttcatc tataactttc tctctgaaca gcgcaccacc gccaccttta
    22681 attatattta aagatggatc tacttcatca gcaccatcaa ttgctaagtc gatatgatca
    22741 acatcattga tttcacatat tttaatacct aattcttttg ctaaaaatgc aattttatta
    22801 gaagtgcata cacctgtaat attgtaacca cgttctttaa ttagttgcgc catttgaggt
    22861 aagagtaatt ccattgtact tcctgtacca attcccagcg tcatgtcacc attgatttga
    22921 cttaaaacat catttaatgt cattaacttg agtgctttga catctttcat gaaggtagcc
    22981 tcccatattt atgtaatcta ttcaattcat attttacatg actcgtataa attaacatac
    23041 ccttatttct aacatttttt taaacatatc aatcagaatt tacaattcta aaaatgtttt
    23101 atagtacaat atattttaaa taatactcgt taaggagaat gatatgatat caattcacgc
    23161 aatttcgaca ggaaaaatcc aagatttgcc ttatagctcg aaaagaccga tacgctctgc
    23221 tttagataaa actaagattt cacaaacaac atggttatct tcaactggtt tcactggtga
    23281 tgaacaggct tataaagatc atggtggacc acataaagca gtttgtgggt ttagtaagca
    23341 taattatgca ctgtatcaag atgatttacc tacactacct actcatgcga tgtttggaga
    23401 gaatttaaca tttgattatt tagacgaatc tgatgtttac tttggtaatc aatatcgttt
    23461 aggtgaagcg ttaattgagg tttctgaaat tagagaacca tgctggaaaa ttcaagcaaa
    23521 atataatatt cctgatttag tgaagcgcat gtctacatct ggtaaaacag gtttctattt
    23581 ccgggtatta aaacaaggct atgtatctcc aaatgatcag ctttacttaa tacaagaagc
    23641 accaatcgaa catcgtttat ctgtacaaca gcttaatgac ctttattata atgatagaca
    23701 aaatcaagat atgttacgat atgcactaaa caatccattt ctgtcaccaa caagacgcga
    23761 taaacttcaa aaaatgtata acagaacatt gaaataatta cctttcatta taagtgttaa
    23821 atgaactttt caaaacaaaa aggaatcaac ttacacatcg tttgtataat agtcttatct
    23881 ataaccactg atgctattga ttcctttttt
//
LOCUS       DAPDIM010000043        22510 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000043 DAPDIM010000000
VERSION     DAPDIM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 22510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22510
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.043"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(109..876)
                     /locus_tag="RFE25_001819"
     CDS             complement(109..876)
                     /locus_tag="RFE25_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2816873.1"
                     /translation="MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSY
                     TYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYT
                     NNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCT
                     YYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGV
                     NSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH"
     gene            complement(1237..3048)
                     /locus_tag="RFE25_001820"
     CDS             complement(1237..3048)
                     /locus_tag="RFE25_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDU2816874.1"
                     /translation="MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSG
                     GFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFT
                     LIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLL
                     FPLVITLLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLL
                     GCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYII
                     SFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIP
                     VYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSI
                     VVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLI
                     GDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNG
                     AFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASA
                     GHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK"
     gene            complement(3561..4049)
                     /locus_tag="RFE25_001821"
     CDS             complement(3561..4049)
                     /locus_tag="RFE25_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2816875.1"
                     /translation="MAINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIE
                     HNYLNSGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDKGYRNLKIGKKLLDKV
                     IMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNL
                     KD"
     gene            complement(4325..5026)
                     /gene="isaA"
                     /locus_tag="RFE25_001822"
     CDS             complement(4325..5026)
                     /gene="isaA"
                     /locus_tag="RFE25_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase IsaA"
                     /protein_id="HDU2816876.1"
                     /translation="MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAH
                     NHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADY
                     TTSYNQGSDVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
                     AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINA
                     AVKAYKAQGLGAWGF"
     gene            complement(5634..6689)
                     /locus_tag="RFE25_001823"
     CDS             complement(5634..6689)
                     /locus_tag="RFE25_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDU2816877.1"
                     /translation="MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDY
                     HPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAW
                     MITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKM
                     ITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIG
                     ISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSA
                     LVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADII
                     YRKVFRLYTNDIFKFMG"
     gene            complement(6816..6944)
                     /locus_tag="RFE25_001824"
     CDS             complement(6816..6944)
                     /locus_tag="RFE25_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816878.1"
                     /translation="MDFKNEDKIKVYCNNMFEKLPIYLSKNSEFCDILFFIVLSYR"
     gene            7099..7668
                     /locus_tag="RFE25_001825"
     CDS             7099..7668
                     /locus_tag="RFE25_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDU2816879.1"
                     /translation="MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIAT
                     LNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDA
                     AKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLA
                     LHWFNTSQETADVFIDRNLPFLIHHIAHF"
     gene            7866..8366
                     /locus_tag="RFE25_001826"
     CDS             7866..8366
                     /locus_tag="RFE25_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816880.1"
                     /translation="MTSIFVFAYLNNTSGNMLFRQQMICACLLANVRHSSIVCLNNIC
                     CIVDMRCLNTKIGGIDVSETDEPQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHI
                     IIARGKKRIDYRLSYNFYTTYYDNVEIKKIDCEYTYAMPIAILIRHTMSFDNAHFFAQ
                     LRHPVL"
     gene            8586..8816
                     /locus_tag="RFE25_001827"
     CDS             8586..8816
                     /locus_tag="RFE25_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDU2816881.1"
                     /translation="MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLT
                     TFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN"
     gene            complement(9118..9495)
                     /locus_tag="RFE25_001828"
     CDS             complement(9118..9495)
                     /locus_tag="RFE25_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDU2816882.1"
                     /translation="MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIG
                     QTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGAVVQEPT
                     VSQGFYGAMFKDLDGHHFNFLVC"
     gene            complement(9512..10333)
                     /locus_tag="RFE25_001829"
     CDS             complement(9512..10333)
                     /locus_tag="RFE25_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NmrA/HSCARG family protein"
                     /protein_id="HDU2816883.1"
                     /translation="MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIG
                     HPHLSIVEGDLSDNVSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQ
                     HIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDER
                     ITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSE
                     VTGKSTVIEGEFVSGVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQNYNK"
     gene            complement(10353..10652)
                     /locus_tag="RFE25_001830"
     CDS             complement(10353..10652)
                     /locus_tag="RFE25_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2316 family protein"
                     /protein_id="HDU2816884.1"
                     /translation="MSLNKEQRRITAEELQAHFEESTLSVQMIAEKLNVTTEDVEKVL
                     AMTAPLGIFSHQLQRFIHLVWDVRDVINDNIKGNGQTPEPYTYLKGEKEDYWFLR"
     gene            10783..11340
                     /locus_tag="RFE25_001831"
     CDS             10783..11340
                     /locus_tag="RFE25_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDU2816885.1"
                     /translation="MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTL
                     YRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALL
                     QCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIE
                     HRHISIEAYRNYLLNIYLDEVERND"
     gene            11333..12037
                     /locus_tag="RFE25_001832"
     CDS             11333..12037
                     /locus_tag="RFE25_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDU2816886.1"
                     /translation="MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQ
                     KLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEV
                     YQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSS
                     KSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGA
                     DGPTGTFINGDGEMPW"
     gene            12135..13145
                     /locus_tag="RFE25_001833"
     CDS             12135..13145
                     /locus_tag="RFE25_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDU2816887.1"
                     /translation="MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTG
                     FTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIA
                     QYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKT
                     AENLDVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSG
                     IFDRYPKLNMIIGHWGEFMPFFLERMDEALFAEHLNHSVSYYFKNSFYITPSGMLTKP
                     QFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSS
                     NN"
     gene            13165..13995
                     /locus_tag="RFE25_001834"
     CDS             13165..13995
                     /locus_tag="RFE25_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2816888.1"
                     /translation="METLELQGAKLRYHQVGQGPVLIFIPGANGTGNIFLPLAEQLKD
                     HFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGS
                     SSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGM
                     KTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKY
                     SDKIALLNGTDSRGSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNMWG
                     "
     gene            complement(14142..15032)
                     /locus_tag="RFE25_001835"
     CDS             complement(14142..15032)
                     /locus_tag="RFE25_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDU2816889.1"
                     /translation="MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSV
                     DGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLD
                     ACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSAD
                     VETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHESLHKTINHQFVQ
                     SPVTCTKAEFIKRLACLPSHIYRLKGFMTFEDTTHTYLIQFTQGQYELTPVAFSKKVP
                     EYLVLIGKGISKEDYQCLEQ"
     gene            complement(15129..16469)
                     /locus_tag="RFE25_001836"
     CDS             complement(15129..16469)
                     /locus_tag="RFE25_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter B"
                     /protein_id="HDU2816890.1"
                     /translation="MLEVKYDMRTGHYTPIPHEPHYLVISHADKLTATEKAKLRLLII
                     KQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPI
                     GIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVV
                     ILISLSTAIIDQTGLKSWMIWAIEPSMLWIGLQGNDIVPLLEGFGCNAAAISQAAHQC
                     HTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLK
                     KNDQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPI
                     LNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLV
                     FFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMVTSLSLVIGVGIIVKIVMLII"
     gene            complement(16463..17569)
                     /locus_tag="RFE25_001837"
     CDS             complement(16463..17569)
                     /locus_tag="RFE25_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HDU2816891.1"
                     /translation="MQHHKVAIIGAGAAGIGMAITLKDFGITDVIILEKGTVGHSFKH
                     WPKSTRTITPSFTSNGFGMPDMNAISMDTSPAFTFNEEHISGETYAEYLQVVANHYEL
                     NIFENTVVTNISADDAYYTIATTTETYHADYIFVATGDYNFPKKPFKYGIHYSEIEDF
                     DNFNKGQYVVIGGNESGFDAAYQLAKNGSDIALYTSTTGLNDPDADPSVRLSPYTRQR
                     LGNVIKQGARIEMNVHYTVKDIDFNNGQYHISFDSGQSVHTPHEPILATGFDATKNPI
                     VQQLFVTTNQDIKLTTHDESTRYPNIFMIGATVENDNAKLCYIYKFRARFAVLAHLLT
                     QREGLPAKQEVIENYQKNQMYLDDYSCCEVSCTC"
     gene            complement(17902..18198)
                     /locus_tag="RFE25_001838"
     CDS             complement(17902..18198)
                     /locus_tag="RFE25_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HDU2816892.1"
                     /translation="METIGSIIYLKEGSQKLMIINRGPIVEIENQKYMFDYSACKYPI
                     GVVEDEIYYFNEENIDSVIFKGYSDQDEVRFQELFENMKQNLDSEIQRGEVTPQ"
     gene            complement(18186..18554)
                     /locus_tag="RFE25_001839"
     CDS             complement(18186..18554)
                     /locus_tag="RFE25_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816893.1"
                     /translation="MSNKLDGINKMITAKHKQMDDLYDEKREVKALIDESDELNHSIE
                     QLYQHLGDRYHSSNMASRMEQFRDEFHFAKRRSTEALYEQQQQIQHGIRKAEEEMIDL
                     EMRRNVEIETVTKEENKWKQ"
     gene            complement(18569..18847)
                     /locus_tag="RFE25_001840"
     CDS             complement(18569..18847)
                     /locus_tag="RFE25_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HDU2816894.1"
                     /translation="MMSTVQSDIFKTNSASSSIKSAVETCNNVSKPDKDESTTVSGNN
                     NAHSVIDDLISKNQSVAEAIRNASDSIQKVGEEFNQTDVMIGNEIGKN"
     gene            complement(18993..19808)
                     /locus_tag="RFE25_001841"
     CDS             complement(18993..19808)
                     /locus_tag="RFE25_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDU2816895.1"
                     /translation="MTKHQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSS
                     RYYTNWNTIEKQVNHRGWEDLASKTTDDILSVNKIFYTAPAEKQTRLSNDLYSISASI
                     DLGQKLHIVNKYGHDHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMI
                     FIGMPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDY
                     EAITTIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
     gene            complement(19801..21243)
                     /locus_tag="RFE25_001842"
     CDS             complement(19801..21243)
                     /locus_tag="RFE25_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDU2816896.1"
                     /translation="MKNKEKYLTNFSEAKRKEATQKYNIIKPFILGKQSLSSISKSKG
                     IALSTLYRWNKLYKEQGLTGLIHNTRVDKGEHKLKQNIIDEIKRLALKNKRNSIATIH
                     RKIVNYCIENNFDKPSYKQVYSIIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPN
                     EIWQADHTLLDIYILDQTGNINRPWLTIIMDDYSRAIAGYFISFEAPNAQNTALTLHQ
                     AIWNKNNTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIE
                     RFFQTVNQTFLEQLPGYINNNDTPSDLIDFQNFEEKLRYFLIEDYNQKEHSVIQSTPI
                     NRWNSNHFFPNMPSSLEQLDLLLLEIPKSRKIHSDGIHFQGFRYSNTNLAAYVGEYVL
                     IRYNPNDMAEIRVFYRDEFLCTAISPDLADYSIDIKDIQHARSQRRKHLKQNIASPST
                     TDLIKEEKNYGYSPQETTKNVKKLKRYRND"
     gene            complement(21215..21808)
                     /locus_tag="RFE25_001843"
     CDS             complement(21215..21808)
                     /locus_tag="RFE25_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDU2816897.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNAYGCEKIFSDHISGSKSKRPG
                     LDKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSST
                     GQLLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNG
                     TPIKTIAEQWQVSRTTIYRYLNKLEEKEDEKQGEVSN"
     gene            22014..>22510
                     /locus_tag="RFE25_001844"
     CDS             22014..>22510
                     /locus_tag="RFE25_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDU2816898.1"
                     /translation="MPKIINHKEKKKQIIQYAFDSIVEKGVKGSTVRQIAKLADMTPG
                     QIRYYFPNHSELLNAVMSTVELKVRRRIEAIFKSENLTTIDKAKASLLTVLPLDKERL
                     ADMEVWMAFRNDIHEYGQSTLDDGLDQLCNSILTLLKNDHLLKNNVNIHLNSMKLHAL
                     IDGLA"
BASE COUNT         7324 a         4015 c         3429 g         7742 t
ORIGIN      
        1 agttccctaa agatcagtga ataaaccgct ctcatttata tttatataaa acaaaaacgc
       61 caatactctc atgttagaga atattgacgt catttgattt acatttgatt aatgaatgaa
      121 attatatgaa cctgcttggt ttgctgaaat tgtacgagac gtaaccacac cagcaccatg
      181 tccatagttc atttctgaaa cacgaacaga accgttgctg ttaacgcctt caacgtaagc
      241 aacatgaccg taatagcctt gtgttgtttg catgatagca ccaacttttg gtgtattgtt
      301 cactgtatag ccagatgatg cagctgcgtt agcccaatta cttgcgttac cccatgttga
      361 accaattttc ccaccaacac gatcaaatac ataataagta cattgtcctg aagtatataa
      421 gttacttcct gatgcataac cattagaaat tgaacgacca tttgaagatg gcgctgcagt
      481 tgtagtcaca tgaacattat tacttgttgt gctataactt gcacctgaac caccagtata
      541 atagttattt gttgctgttt ggctattgtt tgtatagtta ttgtattgat atgaatgatt
      601 atagtagtta ttgtaagatg cattgttata actataagta ttgtagttgt tgtagtagta
      661 tgtgttgttt tgcgttaatt gacttggatt ccaatttcct gtccaagtgt aatgataatt
      721 accttgtgca tcaattgtat acgtatagct gtatgattga gcgtcattag aattatatcc
      781 attgttattt tgttctgcgg cttgtgcatc atgtcctgca aatgcgatag tggcaagtcc
      841 tgctgtagcg attgtagctg taacgatttt tttcataatt aaatatcctc ccaataatca
      901 aaacactcta tacatatagt cattagcgac tcaattattt taaattttat attttttatt
      961 tttttagtat gcaaataatt ataactttta tagttttgcg acaaaacaaa ctataacaga
     1021 gattaggtgt cttgcgggct ttattatcat aatgtaatct gttcctaata aagcttcatt
     1081 gaatgtaata taccaattag aatgtttaca acactttttc tgcaccgtta acatgggatt
     1141 tgaaaataaa aaagcactaa acttttaatg aaatacatca tttttgataa taaatatcag
     1201 aagtaatgta atatttcaaa agtttagtgc atcaagttat ttcttatttg tagcatgtgt
     1261 ttccatcgtt tttacaatca aatcagtcag cgctttacta cctgcatatt ctaagtgaat
     1321 accgtcatat gcaaagtatt ccggatgacc tgcagaagct ttataccaat cgactagatg
     1381 tacattagag cgcttttcag ctgcctcata aattaattta tttattctac cttcataatc
     1441 tctaggtact ctaatagaaa ctaaatatat gtctgctttt ccaaaactat ccaatagttc
     1501 atttaattga tctttcgtaa atgccccatt tgtaccaagc tctactacaa ctttttgacc
     1561 ttttttagca tagtctttat attgcgattt cacaattggt gtagcatcaa cgagttgccg
     1621 tccaacttta ccatcaattt gtgcatttgg tattttctta gtaaagacat taccaatatc
     1681 caccatgacc gagtcaccaa ttaatagtgg tgatgacttt ttaatatcct ctttgctatt
     1741 cgctgtctgc ttatcctctt gcttatcttt tttaacgact tttttcttcg ttgttttaaa
     1801 ttccgtcttc ttctctttct tctcggcttc atgttgtttg ccaagtgcat caaactgtcc
     1861 actgagcaca acgatagacg gaaccaataa taggataact aacactgttc tagcaaattg
     1921 ccccttcttt ttaggtaaaa atgcaaaagc tttaaatcct tttttacgta taggtgtttc
     1981 aataaagcga tacgaaattt cagccattaa cgctgttaac aaaatttcta taatataaac
     2041 gtataccggt atttgtcctt gtacgtaata actgttcaca aaaacaatga taggataatg
     2101 ccataaatat aagctatatg atcgtttacc tataattagt aaaggtttca tacttaaaaa
     2161 tttagcaaat aaactagaag gatgtaccgc aattgcaata atgaataaag ttgcaaatga
     2221 tataatgtaa aatcctccat tatagatcca ttgatcttgg tcgccaacta taaagaacaa
     2281 agtcattaga accgcaaaac cagatatccc tataatatct aatgatacga caatcttttt
     2341 agaaatatct tttttcaaag caaacggagg ccaaataaat gctaatatac aaccaagcaa
     2401 taaagtttgc agtcgtgtat ctgtcccaaa atacacacgt gaattatctc cagtgatgaa
     2461 atgaatcact atcataagtc ctaaagaaat caacgataca ataaatagcg tttgaataat
     2521 atttctcggt ttaaatctat gtaataagag cgtgataacc aatgggaaaa gcaagtaaaa
     2581 ttgttcttca atggctaaag accataaatg tttgagtggt tcaatagcaa attggttaaa
     2641 ataatctaca ttctgtgaaa tgtaccacca gtttgaaaca tagaatatag ctgcaatagc
     2701 atctcgtttc atttgtataa tcaattccgg tttaaatatc agtgtgaacg taagcacgac
     2761 acagattaaa aataacactg ccggaatgag tcgtttcaat cgtcgcttcc aaaactctag
     2821 caaatcgatt ttttgcgtcc gataatactc acttatcaac aaacttgtta ttaaataacc
     2881 tgaaataacg aagaatgtat ctactcctaa aaagccccca cttaaccatt gtgcattcaa
     2941 gtgataaata atgattccta taactgcgaa tgccctcaat ccatctaatc cgggtaagta
     3001 tcgcggggaa tacatttttt ctaaacgttt aaagtctttt gtatccatgt taataaacgc
     3061 cccatttatt tttctctatt ttgtagcata tcacaatatt tttgaaaata aaatattgca
     3121 ctgattttca ttaattgatt taacccttaa ttaagatagt tttaaatttt ttattaagta
     3181 gaaaacaatt attacagtta atttcattac tgcaaaccac atataaattt gtcgatttta
     3241 ctacataaca tagattatca tagattcttg aatttttagc aaaataactg ttattttcat
     3301 tatattttta caaaaaaagg ttcgttttat attttatgca tcttactgta acagaatcat
     3361 taagatatgc tattcgaatt tactttttca aaatttctat aatgaataaa ttaccatgta
     3421 ttgaaaataa agcgaaatgc agcctatcct ctaatttaaa ccaagcgata tatcacgtca
     3481 gcctttatat ttaaacgcta tgtgtcactt ttaaaatgaa tattactaag attgtcatac
     3541 caattattca ttgcatcgaa ttaatctttt aaatttctgt aataaaacct attatctaca
     3601 tctaatttag gaaaactact tggtaaatct cctcgcttaa tttcacggaa gccattatta
     3661 gaataaaaat actgtgcact aataaattta tcaattgttc ctaaataaat accatcgata
     3721 ttttgttctt tacatgtcat tataacttta tctaaaagtt ttttacctat ttttaaattc
     3781 ctataacctt tatcaacaaa cattttttta agtgcagaca tattattatc tagtctaatc
     3841 aaacctatag taccaacaat attttgatga ttgtttattg caagccaaaa ttgccctcca
     3901 ctattcaaat agttatgttc gatgttctcc aaatcaggtt gatcatctct atcaattttt
     3961 atattaaatt catttttttg aatcgataaa ataaactcga ttagctcttc cttataagac
     4021 ctattatatt caattatgtt tatagccatt tttatctcct ttttcattta atttaatcat
     4081 aaaatgcgcg tttagtttgt atctagtgta ctcagtacag cctcaaatga agttttattc
     4141 cacttggcac ttaataaaga caagtatttt agcagtaata caataaagtc caataaattt
     4201 ccctaacttc aatatccact ttttaagaaa tgtattttta attaataaaa aaactctccc
     4261 caatttctat gggaagagct atatatttaa tgtctaaaca ttacttttat ttattatgaa
     4321 ggaattagaa tccccaagca cctaaacctt gtgctttgta tgctttaaca gctgcgttga
     4381 tttgttggtc aacagtgttt gtcggacccc aacctggcat agtttggaat aaacctgaag
     4441 cacctgatgg gttgtaagca tttacttgac catttgattc acgagcgatg attgcagccc
     4501 atgtagaagc tgaaacacca gtacgttgag ccatgatttg agctgctgat gaaccagtag
     4561 cacctgcagt attaccattg cttaatctca ctgaacttga agtagttgaa gtgctgtagt
     4621 tatggtaagt tggagctgaa acagcttcaa cgtttgagtt acttgattgt gcattgtagc
     4681 ttactgattg tacatctgaa ccttggttgt atgaagtagt gtagtctgca cctgcaacgt
     4741 ttgagaaacc agcagtttga ccattagctg cttcatagct ccatgaccat gtagtaccat
     4801 ttgaagtaaa gttatattgg aaaccatctt ttacaaagtg gatgtcatat gcaccatctt
     4861 tgattggagc tgcatttaat tgatcttggt gattatgcgc taagtcaact aagtgtgctt
     4921 gatcaacgtt tacttcagca gcgtgtgctt gatgtcctgt acctgctgcg taacctgtta
     4981 cacctaatgc cactgctaat gatgatgcca taattgtctt tttcatagta aaaaatcctc
     5041 cagtaataat tgtaagttta tgtttttagt aattatattt tgaatttgaa tgtcgtagtg
     5101 caagtttaaa ttgtctttta tttctttcaa cggtactcac tatatcacaa aaaaccagcc
     5161 agtaaattac actttcttta caaaacatta caatatcaag tgttatttgt aatgttgaaa
     5221 tatggctgtt ttatactgta atgtgaaata tgtgcccttt agaatccaat caacccttga
     5281 aatagtcttt aacacataag atttttacta tatttagctc aactattaca gctttcgtaa
     5341 tattacagat tgtatttttg ttacatagct gtaatatatc tgacatgtaa cttctcttat
     5401 tttcgtacat taaacgcaat taaaaagcaa tcaacacata tgtttctgca catgtattga
     5461 ttgctattat tgttgtatat tcaaagtttt aaaacacaca tcttttgtga attatcttat
     5521 cttttataag cacaaataaa ctgcaactca attatattgc taaactttat tctcgcaatt
     5581 cacaataaca ttaaataatt tttggtctaa tattttcaaa aaacatactg tccttatccc
     5641 atgaatttaa aaatatcatt agtatataaa cgaaacactt tacgataaat gatatctgca
     5701 agccaagctg ttacaaatgg cacaacaaag aacgctacta caattagtaa gacgctcaac
     5761 caagcagaat caacctccat aaatttaaat gcattaatcg gtcctaccat tcctataaaa
     5821 ccaaatccag ctgattcttt cgttccatga atacctacta atgctgatac caaacctgat
     5881 acaatggctg ttgtcaatat tggtaacata agaattggat atttcaccat attaggtatc
     5941 atcattttaa cgcctccaaa gaagacggat aacggcaccc ctaaacgatt cactttactt
     6001 gtaccaatta tcaatactgc ttcagtcgcg gagataccaa ttgacgctga tccagctgct
     6061 aaacctgtaa tacctatcgc aaaggcaatg gccacagttg atagtggcga aataataata
     6121 agactaaata ccattgaaat caaaatactc atgacaatcg gttgtaattc tgtaaaacca
     6181 ttaaccatat taccgatggc tgttgtaatc attttcgtat acggcaatat taaaacacca
     6241 attgcacctg aaataccgcc aacaactgtt gggaatacaa tcaatgccat actacctaca
     6301 cgatgttgaa taagtaaaat gaacaacact gcaatcgctg ctgtaatcat tgtattaatt
     6361 aaatcaccaa tacccgtaat catccaagca ccatttttaa actgcgctgc accgcttcct
     6421 acatatgctg cacttgccac aacagcaatt gctaatggcg ataggtcaaa tttcatggca
     6481 accaatgcac caatcaaagc aggtactgta aattgaattg caacgacaac gcctaataac
     6541 gttttaaaaa tcggatgata atccataaag tatttaaaaa tttctccaag tatcgcatta
     6601 ggaactaaac ccgcaacaat acctatggcg acacctgata aaactctaaa tataaaatct
     6661 ttgggtgtaa ttgttttaat tgatgtcata atatcatcct tccatttatg tatatacatc
     6721 tgtatgcaaa taataaagag ccttaagtta taagctgcca ctagcttaaa ttctaagatg
     6781 tgcatgccga tgttgttata tttaggctag cagtatcatc tataactcaa gactatgaaa
     6841 aatagtatat cacaaaattc tgaattttta gataaataaa ttggcaattt ttcaaacata
     6901 ttgttacaat acacttttat tttatcttca tttttaaaat ccattaatac aatagaagaa
     6961 agacattcaa atgcttacca aaaaggtaca ttatttgtta ggagcgtatc aacacttaca
     7021 tatcatcaac acaattgaca atataataga agatactgat aataagtgtt aaaacaacag
     7081 atgttaggta gtgaacaaat gatggaaagt aaatccatag atccaagaat cgttagaacc
     7141 aaacaattgc ttgtcgatgc ttttcttaaa atttctagag aaaagaaatt atctcaaatt
     7201 acagttaaag atatcactga tattgctacg ctaaatcgtg caacatttta cgctcatttc
     7261 actgataaag aagacctcct agactacaca ttatctgtaa ccattttaaa agacttgaat
     7321 gataacttga gcatttctaa tgtcattaat gaaaaggtgc tgcgtaatat tttcatttca
     7381 attgcgagtt atatcaaaga tgctgcaaag tcttgcgaat taaatagtga agcattttgc
     7441 aacaaagcac atcaacgtat taataatgaa ttagaagata tttttgcgat tatgttagaa
     7501 aacagctatc cggagcatca acgagatatc attgtaaata gtgcgagttt tttagcagct
     7561 ggtatctcag gcttagcatt acattggttt aacacgagtc aagagacagc cgatgtgttt
     7621 atcgatcgca accttccatt tttaattcat catatagcac atttttaata aaacttggta
     7681 tttagtcatg catcttgaaa tcactatgtg acttaggttc atacttgtac acacaataaa
     7741 atttaacata ttacgattga ttagccgtgt ctaggacata aatcaacgtc ctatactcta
     7801 caatgtcata ttagcagtcg ttaactgaat gaaaataagc ttgtcattaa aacatataga
     7861 ttttagtgac aagcattttt gtttttgcgt acttaaacaa cacttcaggc aatatgttgt
     7921 ttaggcaaca aatgatatgt gcgtgtttat tggcaaacgt acgacatagt agtatagtat
     7981 gtctaaacaa catatgttgc atagttgata tgcgttgttt aaatactaag ataggaggga
     8041 ttgacgtgag cgagacagat gaacctcagg ggtttgaacg cacgcataat atattaaata
     8101 ttaatcagag tagtctgggt gtagtgacat acattacaaa taaattaaag tcgacgttga
     8161 agcaacacat aataattgct cgtggtaaaa agcgaatcga ctatcgactg tcgtataact
     8221 tttacactac gtattatgat aatgtagaaa tcaagaaaat cgactgtgaa tatacctatg
     8281 ctatgcccat tgcaatttta ataagacaca cgatgtcatt cgacaatgct catttctttg
     8341 ctcagttacg tcatcctgtc ttataaaaca acattgcaga catgtatatc aaacgacact
     8401 tcaataacat cactttgcca tcgtactact attaaaatcg tgtctcaaac cccttatttt
     8461 aattccaaaa atctgctggt caaaagaccg agaaactaaa aacattactg gatgtgttga
     8521 taaattatct tatagaaata aactcaaaat atatcaacac ttgattctaa ggaggatatg
     8581 acaatatgaa aattttagat agaattaatg aacttgcaaa taaagaaaaa gtccaaccac
     8641 ttactgtagc tgaaaaacaa gaacaacatg cattgcgtca agactactta agtatgatcc
     8701 gaggacaagt attaacaaca ttttccacaa taaaagtggt tgatccaatc ggtcaggatg
     8761 tcacaccaga taaagtttat gatcttcgcc aacaatacgg ttatattcaa aattaatatt
     8821 tgctcacgag gtattgcact taaggtgcca actgacctca taaacaaagc ccatactgat
     8881 tgaagacact aatgtgtcca ggctgggaca taaatcaatg ttctatgctc tacgaagtta
     8941 tattggcagt agttgactga atgaaaatgc gcttgtaaca agcttttttc aattctagtc
     9001 aaccttgccg gggtgggacg acgaaataaa ttttgcgaaa atatcatttc tgtcccactc
     9061 ccacattaaa cttcatctct gtatgggctt tttatttatt cttttgagaa tttcatttta
     9121 gcagactaaa aaattaaaat ggtgtccatc aagatctttg aacattgcac cataaaaccc
     9181 ttggcttact gttggttctt gaacgactgc gccacccgct tctttcactt tattcaccaa
     9241 ctggtcaact tcttcatttg tgttcacacc tagagaaatc atcacttcat ttggttcagt
     9301 attaaggctt tgctgactta cattttgaaa atgcttgttt tctattaaaa ttacggttgt
     9361 ttgacctatt tgaataccga ccattttatc taacatttgt gggtttctat ttattttaaa
     9421 tcctaacgct ttataaaact gtgcgctctt ttctaaatct tgcacatgca aattaaacca
     9481 cattgattga atcatgattg caccccattc attacttatt atagttttgg actttaagcc
     9541 aatcacttaa tgataatctt gttggattta tttcagccat taattcaaag tctacttcat
     9601 aacctttttc ttccaaccat tgcttttctg caacaccact aacaaattct ccttctataa
     9661 cagtagattt acctgtcact tcactaaaaa ttgttgctgc ttcacttaat gtaacttcat
     9721 cggaaccaat ctctattgat tgatgcgtaa agctttgtgg atgtgcaaaa atatacgatg
     9781 caattttagc tatatcaata gaagaaatca ttgtgaattt tatattcgga ttaataaatt
     9841 ctggtaatgt aatacgttca tcttcgactt tagcaatgcg taaaaaatta tccataaaga
     9901 atgatggttt gataactgtt gcatttatat tagattccat taatctattt tctatttttg
     9961 ctagtacttc aaagtgtggg ccagttcgat ttcgattaac ccctcccgca gtactataca
    10021 caatatgttg aatattttct tgctcagcta tttcaattat cttcatacct tgtcttaatt
    10081 cttcgctaac atcatcttta acgattggct gaatactgta taagccatac ttccctttca
    10141 tcgctgattg caaactaaca ttatcactca gatcaccttc aacgattgat aaatgcggat
    10201 gtcctatgtc tgaaagttta cgattattct tatttctagt taatgcactt acataccatc
    10261 catcctctaa caactgtttt acaactgcat taccttgctt ccctgttgcg cctattacta
    10321 aaatatcttt cattttagat ccactcctct ttttatctta aaaaccaata gtcctctttt
    10381 tcacctttta aatacgtata tggttctggt gtttgtccat ttcctttaat attgtcgttt
    10441 attacatctc tgacatccca tactaaatga ataaatcgtt gtaattgatg actaaaaatg
    10501 cctagtggcg ctgtcatagc taatactttt tccacatctt ctgtagtgac attcagtttt
    10561 tcagcaatca tttgaaccga taaggtagat tcttcaaaat gtgcttgcaa ctcttcagct
    10621 gtgatgcgtc tttgctcttt atttaaagac attatcaaca ctcttttctt ttatgatatt
    10681 taatagttat tgcaaattca ttgctaactt tcttaacacg ttttataata aacggatagt
    10741 tatccgtttg tcaattttag agaattttaa gtaggtgtaa tcatgcgaaa agatgcaaaa
    10801 gagaatagac aacgaattga agaaatagcg cacaaacttt ttgatgaaga aggcgttgaa
    10861 aacattagta tgaatcgtat tgctaaagaa ctaggtatcg gtatggggac attgtatcga
    10921 catttcaaag ataaaagcga tttatgctac tacgtcatac aaagagacct tgatattttt
    10981 atcactcatt ttaagcaaat taaagatgac tatcattcta attatgaggt tatgcaagtg
    11041 tcgttagatt atcttttaca atttaaaatc gataataagg cactactgca atgtattgaa
    11101 gcaggcaaca ataaattacg tttttaccaa agcgcatttt atcaagaatt atttgatttt
    11161 tattatgact tatttaaaag cgatgacgac acttacacga agttcaaaac agatatgctg
    11221 ttgcaatcat tatcaactag tgtatttgcc ttccaaatag agcatcgcca tatttcaatt
    11281 gaagcgtaca gaaattattt attaaacatt tatttagatg aggtggaacg taatgactaa
    11341 aattgtgtta atcacaggag gcaataaagg gttaggctat gcaagtgcag aggcacttaa
    11401 agcattgggt tacaaagttt atataggttc tcggaatgat gtaagaggac aacaagcatc
    11461 acaaaaatta ggtgttcatt atgtacagtt agatgttaca agtgactact cagtcaaaaa
    11521 tgcttataac atgattgctg aaaaagaagg ccgtcttgat atcctcatta acaatgcagg
    11581 tatatctggt caattttcag caccttccaa attgacacct cgtgacgttg aagaagtata
    11641 tcaaacgaat gtattcggta tcgtacgaat gatgaataca ttcgtccctc tcttagaaaa
    11701 atctgaacaa cctgttgtcg tcaacgtatc aagtggttta ggttcatttg gaatggttac
    11761 aaaccccgaa acagctgaat ctaaagtgaa ttcattagct tattgttcgt ctaaatcggc
    11821 agtaacaatg ctaacgctac aatacgctaa aggattacct aacatgcaaa tcaatgctgc
    11881 tgacccaggc gctacaaata ctgatttagt tggtgatttt agtaataatt ccaaacacgt
    11941 ttctgaagga atcaagccaa tcattcaatt agcaacgatt ggtgcagatg gcccaacagg
    12001 tacatttatt aatggcgatg gagaaatgcc ttggtagatc aattttatgt tacaaacatt
    12061 gaaattagag gtatataaaa aatgcttctg caatagatgc aatatacatg caaaacaata
    12121 tggaggcgaa ttaaatgaaa agtattacgt ttgaagaaca ttatgtcatt gaagatattc
    12181 aaaaagaaac gatgaatgcg atatcagcag atcctaaagg tgtaccgatg aaagtaatgt
    12241 tagaaggcct tgaaaaaaag acaggtttta caaatgccga cgaattatca catcatgatg
    12301 aacgtatcca atttatgaat aatcaagacg ttcaaattca agtcttatct tatggaaatg
    12361 gatctccttc aaatttagtt ggtcagaaag ccattgaatt atgtcaaaaa gcaaatgatc
    12421 aattggcaaa ctatattgcc caatatccca atcgctttgt aggctttgca actttaccta
    12481 tcaatgagcc tgaagccgca gcgcgagaat tcgaacgttg catcaatgat ttaggattca
    12541 aaggtgcgct cattatggga cgtgcacaag atggttttct tgatcaagac aaatatgaca
    12601 ttattttcaa aacagctgaa aatttagacg taccgattta tctacatccc gcgccagtta
    12661 acagtgacat ttatcaatca tactataaag gaaattatcc tgaagtaact gcggcaacat
    12721 ttgcttgttt tggttatggt tggcacattg atgtcggaat tcatgcaata catctagtat
    12781 tatctggcat ttttgatcgt tatccaaagt taaatatgat tattggacat tggggtgagt
    12841 ttatgccatt cttcttagaa cgtatggatg aagctttatt cgctgaacat ttgaaccact
    12901 ctgtaagcta ttactttaaa aatagttttt atatcacacc aagtggcatg ttaacgaagc
    12961 cacagtttga tttagtcaag aaagaagtag gtattgatag aattctttat gctgctgatt
    13021 atccatatat tgagcctgaa aaattaggtg tatttttaga tgaactgggt ttaacagatg
    13081 aagaaaaaga gaaaataagt tatacaaatg gtgctaaatt attaggttta tcatctaaca
    13141 attaacaaat ggaggtcatt gaatatggaa actttagaat tacaaggcgc taaattacga
    13201 taccaccaag tcggacaagg acccgtgctc atctttattc ctggtgcaaa cggtaccgga
    13261 aacatttttc tgcctcttgc agaacagtta aaagaccatt ttactgttgt agccgttgat
    13321 cgtcgtgatt atggagaaag cgagttaact gaaccactcc ctgattccgc ttcaaaccct
    13381 gacagtgatt atcgtgtcaa acgcgacgca caggacattg ccgaacttgc aaagtcatta
    13441 agtgatgaac ctgtctatat attaggttca agttcaggtt caatcgttgc gatgcatgtg
    13501 ttaaaagatt accctgaagt cgttaaaaag attgcatttc acgaaccacc aattaataca
    13561 tttttaccag acagtactta ttggaaagat aaaaatgatg acattgtgca tcaaatttta
    13621 acagaaggct tagaaaaagg tatgaaaaca tttggtgaaa cattaaatat cgcaccaatt
    13681 gatgcaaaaa tgatgtctca acctgctgat actgaagaag gacgtataga acagtacaaa
    13741 cgtacgatgt tctggtcaga atttgaaatt agacaatata cgcattcaga tattactttg
    13801 gatgatttca caaaatacag cgataaaatc gccctactaa atgggacaga ttctagaggc
    13861 tccttcccac aagatgttaa cttttatata aacaaagaaa ctggcatacc tattgtagat
    13921 attccaggcg gtcacttagg ttatattcaa aaacctgaag gctttgctga tgtattatta
    13981 aatatgtggg gttaattgat cgttctctaa taaaacagct tggacagttt tcaaattata
    14041 tttgatggct gaccaagctt atttttgttt acgtttaaac gttcaaatca actcgttatt
    14101 atacatgaag gcatgttaac cattctcttc cactgaaaac actactgttc caaacattga
    14161 tagtcttctt ttgaaatacc ctttccgata agcaccaaat attctggcac tttttttgaa
    14221 aatgctacag gtgttaattc atattggcct tgtgtaaatt gaatgagata cgtatgtgtg
    14281 gtgtcttcaa atgtcataaa ccctttcaac ctataaatat gagacggaag gcatgctaaa
    14341 cgttttataa actctgcttt agtacatgtg actggtgatt gcacaaattg atgatttatt
    14401 gttttgtgta atgattcatg tttattgtca gaagttgctg tcatttgtct aactgatatt
    14461 ggcaaagtga cgctgccatg cataccgact tgtatatcgg cctctgggtt aataacttct
    14521 aaatctttca atagtttgct cgttgtttca acatctgctg aatctatttt attaacaaat
    14581 aagacagaac aatatgctaa ttgctcataa aataagcctt ggatgtcttt agggaatgat
    14641 ttaatgtgtt tatacatgct tgcgtctatt acaccaatca tatgtgtaat tgttgtaaac
    14701 ggagctaaaa taggcgttaa acaagcatct aagacagaga ctggttctgc aatcccacta
    14761 cattcaataa atacaatgtc tggttgctct tttaaatata attgatgtaa ctgttctgat
    14821 acatctgctt tcattgcgca acagatacac ccctctgtca gttcacttaa aggtatgtct
    14881 tcagatacta aggcaccatc aacactcatt ttcccaaatt cattcatgat gactgctggt
    14941 ttcagcgatt cctttaatga ttcagcgagc aaatgattta agacagtcgt tttaccgcca
    15001 cctaaaaacc cacctataat aactattttc atctgcgact ctcctcttat acttcatatg
    15061 aatagcatat tccaagatag atctcctatt gactgacatg actctatatt cagttatagt
    15121 tcattttttt aaataatcag cattactatt ttaacaatga tgcctacacc aataactaaa
    15181 gacaatgatg tcaccatttg ctttccaatt aattttagtg ctgactgacc acctaaatgt
    15241 ttcaaaagca tcgtcattgt gaccgagcac gctgtaaatg ttgaactaaa aaacacaagt
    15301 agtagtaact gtgttgctgt cattccttgt aataaggcgc cttgatgcaa attaaacaag
    15361 agcatgccgt cttttcgaat cattgaaaat aaaatccctg gtgacaattc tgaagagatg
    15421 cctaataacg ataatatagg tgtaaatatt tgtgataaaa cattcaaaat tggcgttagt
    15481 gataaaatac taacaataag acagattgtg ataaaaatag gtagcgcttg aacgataaac
    15541 atttgtatat tttgccacat ttgtagcaac atttgacgta tatttggcat atgtaattgc
    15601 ctatcataag gtagcggaac actaagttgt tgatcattct ttttcaacca tatcctatta
    15661 tgtaagatgc cacctaaaag tactaatatt aagtacggca taaatagcca tgactttcca
    15721 gctacactaa aaatagataa tgtcgcacct atttgataac tacaagaact accaaagctt
    15781 attaaactca tacactgtgt cttcgtgcag gtatggcatt ggtgtgctgc ttgtgaaata
    15841 gctgctgcat tacatccaaa tccttctaat agtggcacga tatcattacc ttgtaatccg
    15901 atccataaca ttgacggttc aattgcccat atcatccatg atttgagtcc tgtttgatca
    15961 attattgcag ttgataaact aattaatatt acaaccggca atgcccatac gagcgaatat
    16021 gttccaagtg atagcacacc ataatcacca aataatatat gctgtaatat atcgtgattg
    16081 agcaatgttg tttgagttaa atattctatc catgctgata catactgatt ttgaaaccaa
    16141 tctgaaaatt gataagcgat accaattggc aatgcaaaca ttaaaaatat caacaaccag
    16201 gctaaaaatg tcgcacttat tttaggtctt aaatgtcgtc gctcatgttg aaatagtgtc
    16261 aattgttcta tcacatgttc actcgctata ggcgaagaaa ctacactttc tgccaatgaa
    16321 atatctaatt tctgttttat gattaataat cttaatttcg ctttttctgt tgcggtaagt
    16381 ttatccgcat ggctaataac caaataatga ggttcatgag gtatgggcgt ataatgccca
    16441 gttctcatat catatttcac ttctaacatg tgcatgacac ttcacaacat gaataatcat
    16501 ctaaatacat ttgatttttt tggtaatttt caatgacctc ttgtttagct ggtaagcctt
    16561 cccgctgtgt taaaagatgg gcaagtactg caaatcgcgc tctgaattta tagatatagc
    16621 ataatttggc attatcattt tcaactgttg caccaatcat aaaaatattc ggataacgtg
    16681 tcgattcatc atgtgttgtt aatttaatat cttgatttgt tgtcacaaat aattgttgaa
    16741 cgattggatt ttttgttgca tcaaagccag ttgctagtat tggttcatga ggcgtatgca
    16801 cactttgtcc gctatcaaaa ctgatatgat actgtccatt gttaaaatca atatctttaa
    16861 ctgtataatg tacattcatt tcgatgcgag caccttgctt aatgacatta cctagtcgct
    16921 gacgtgtata aggtgacaat ctaacactag gatcagcatc cggatcattt aaaccggttg
    16981 tgctagtata aagtgcgatg tcagagccat tttttgcaag ttgatatgca gcatcaaagc
    17041 cactttcatt acctccgata accacatatt gccccttatt aaagttatca aagtcttcaa
    17101 tttcactata atgaatacca tatttaaatg gctttttagg gaaattataa tcacctgttg
    17161 cgacaaagat ataatccgcg tgatatgtct ctgttgtcgt tgcaatcgta taatatgcat
    17221 catctgcaga tatatttgtg acaactgtat tttcaaagat attcagctcg taatggttgg
    17281 caaccacttg taaatattca gcatatgttt ctccggaaat atgttcttca ttaaatgtaa
    17341 atgctggtga agtatccatg gaaattgcat tcatatcagg catgccaaat ccattagacg
    17401 taaatgatgg cgtgatcgta cgggtcgatt tcggccaatg tttaaatgaa tgtcctactg
    17461 ttcctttttc taaaataatg acatctgtta taccgaaatc ttttaaggta atggccatac
    17521 ctatacctgc agcaccggca ccgataatag ccactttatg atgttgcata ttaacactcc
    17581 ctcaatgatc tatttcaagt tattgttttt gactataaat cgtaataatt acgatttata
    17641 aagtatagac ctatccttaa gaaatttcaa tattaaaaga aaaacttccg ttattgtaga
    17701 gaattcatct acatttcgga agttggtatg tgtctttttt attaaattta aggatgctac
    17761 ggttagttca aatgattatg aatgacattt aatggtatca tccagcctca gtacttggag
    17821 ataacatttt ggcggtgaga cataaatcat atttttacaa aacttatttc gtcgtctccc
    17881 caataaagat aaagtatttc tttattgtgg tgtaacttct ccacgttgta tttcactatc
    17941 caaattttgt ttcatatttt caaacaactc ttgaaatcta acctcatctt gatcagaata
    18001 acctttaaaa ataactgaat ctatattttc ttcgttaaaa taataaattt catcttccac
    18061 aacaccaatc ggatatttac atgcagaata gtcaaacata tacttttgat tttcaatttc
    18121 tacaattggt cctctattaa taatcattaa cttttgcgaa ccttctttta aataaataat
    18181 gcttcctatt gtttccattt attttcctcc tttgtcaccg tctcaatttc aacattcctt
    18241 cgcatttcca agtcaatcat ctcttcttcc gctttacgaa tgccgtgttg aatttgctgt
    18301 tgctgctcgt ataacgcttc cgttgaacgt cgtttcgcaa aatgaaattc atcgcggaac
    18361 tgttccatac gactagccat attgctacta tgataacggt cacctaaatg ttgatataat
    18421 tgttctatcg aatgattaag ctcatcactt tcgtctatca aagctttaac ctctcgcttt
    18481 tcatcatata agtcatccat ttgcttatgt ttcgctgtga tcattttatt gattccatca
    18541 agtttattcg acatcatttc accacggttt aatttttacc aatttcatta ccaatcatta
    18601 cgtctgtttg attaaattct tcgccaactt tttgtatact atcgctcgca tttcttattg
    18661 cttcagcaac agattgattc ttactaatca aatcgtctat cacactatga gcattattat
    18721 ttccacttac tgttgtactt tcatctttat ccggtttcga cacattatta catgtttcaa
    18781 cggcactttt aatagatgat gatgcactat tagtcttgaa aatatcactt tgaactgtac
    18841 tcattattta cacctcttcc catttaaatt attttaaaat tattagaaac tgtatcaata
    18901 tatgatatgt tactttactt gatatatgag aatgatttta cctagtaaat gagaaaagca
    18961 atgtcctata ttaaagtaca ttgctttttc tattaacgaa tacctatgac taaactatct
    19021 ctagctgttt ctacaacttc tgtactgatt ttatctaagc catttatatc cataattcta
    19081 tctatctgcg caaataaacg atgaatcagc ctaaaattcc cttttgtaat tttaataatc
    19141 gtcgttattg cctcataatc agtaaaatct tcgagtttta gatcaaatcc taaatcttgc
    19201 cacttatatt ctaatatatg atgcgtctcg tctttactta gattatcaaa ttcatgtgca
    19261 aaacctatac gcgaatatag ttgaggataa cgagatagtt ttttctctat acctggcata
    19321 ccaataaata tcattgctaa attatgttca tcataaatag ctcttaattg ctctaaatgt
    19381 tgcactttaa ggcgatcaat ctcatctact ataattaaat caatatattt aaacatatca
    19441 ctataatgtt tactatgatc atgaccatac ttatttacga tgtgtaattt ttgacccaaa
    19501 tcaatacttg cactaatact atatagatca ttacttaatc ttgtttgttt ttcagccggt
    19561 gcagtataaa atatcttatt caccgataat atatcatcag tcgttttact agctagatct
    19621 tcccaccctc tatgattaac ttgcttttca atagtattcc aatttgtgta atacctagaa
    19681 gataaagttt ttccgacacc aggttgacca tagcagatcc caatatattg atatttgata
    19741 caagcatcgc aaaattcagc aaatcgttta tactctttcg tttcaatgaa attctgatgt
    19801 ttagtcatta cgatacctct ttaatttttt gacgttttta gtcgtttctt gaggtgaata
    19861 accataattt ttttcttcct taattaaatc agtggtgctt ggactagcaa tattttgttt
    19921 taagtgtttt cttctctgac tacgtgcgtg ttgtatatct tttatatcaa ttgaataatc
    19981 agctaaatca ggagatattg ctgtacaaag aaattcatct ctataaaaaa cacgtatttc
    20041 agccatatca ttgggattgt aacgaattaa tacatactca cctacataag cagctaggtt
    20101 tgtattactg tatctaaagc cttgaaaatg aatgccatct gaatgaattt ttctagattt
    20161 aggtatttct aataataata aatcaagttg ttctaaactg cttggcatat tagggaaaaa
    20221 atgattactg ttccaccgat tgataggagt gctctggata acactatgct ctttttgatt
    20281 ataatcttca attaaaaagt atcgtaattt ttcttcgaaa ttttgaaaat ctattaaatc
    20341 gctaggagta tcattattgt ttatatatcc aggaagttgc tctaagaaag tttggttaac
    20401 tgtctgaaaa aaacgttcta ttttcccgcg accacgaggg acaccaactt ttgaaaacat
    20461 caagttaatt ttcaaatcaa tagcgacttg ttccatgtga tgcgaggtaa agtcactccc
    20521 gtgatctgtg tagaattttt cgggtatacc acatactggc caattggtat tattcttatt
    20581 ccatattgct tggtgtagtg ttaatgctgt attttgagca ttaggagctt caaaacttat
    20641 aaagtatcct gcaattgcgc gactatagtc atccataata atggttagcc agggtctatt
    20701 aatattacct gtttgatcta atatataaat atctagcaaa gtatggtcgg cttgccatat
    20761 ttcattgggt cttgaggatt ctcttatttg tattaaatcg tacttatttt gatagtattt
    20821 ttcaccttgg tgagagaaat caataacaga cttaggcatt gctttaataa tactataaac
    20881 ttgtttgtag cttggtttat caaaattatt ttctatacaa taattaacga ttttcctatg
    20941 aattgtagca atactatttc ttttattctt gagtgcaagg cgtttaatct cgtctattat
    21001 gttttgtttt aatttatgct cacctttatc aactcttgta ttatgaatta gaccagtaag
    21061 accttgttcc ttatataatt tattccacct ataaagtgta cttaacgcaa tacctttgct
    21121 tttagaaatg cttgataaag attgcttgcc caagataaaa ggttttataa tattgtactt
    21181 ttgagtagct tctttacgtt tggcttcaga aaaattagtt agatacttct ccttgttttt
    21241 catcttcctt ttcctccaat ttattgaggt aacgataaat cgttgtacgt gaaacttgcc
    21301 actgctctgc aattgtctta attggcgtgc cattatcata aagtgtctta agtaagttta
    21361 aatctttttg atttaatttt tcgggtctac ctccatagcg tcctctagca cgtgctgcaa
    21421 ttcggccagc tgaagaacgt tctaaaatta aatttcgttc aaattctgca aacgctgcga
    21481 ataaatgaaa taataattgt cctgtagaac ttgatttatc catcgttata ttttcttcta
    21541 aactatggaa acttacacct cgttcgttaa gctcattaac taatgtgatt aaatcctcca
    21601 tattacgtcc tagtctgtcg agtctccaaa caacaatcgt atctcctgat ctcgcaaatt
    21661 caattgcttt atctaatcca ggtcttttac tttttgaacc actaatatgg tcgctaaata
    21721 tcttttcaca accatatgcg tttaatcggt cctcctgtaa attcagattt tgtaatccag
    21781 ttgaaactct tgcataacct attttcaaaa tacaaacctc ctatatacat atacagtgta
    21841 ccataactta atttcaaggt cttttgtgaa catagatttt ttgttgggtt tttgaacacg
    21901 aaaatatatg tattactcac ttatttcggc ataaaaagag agtgtacaga aaatggttgt
    21961 tttctgtaca ctttttttaa cacaactgta ttaaaatgtg ttaacatata actatgccaa
    22021 aaataattaa tcataaagaa aagaaaaaac aaatcattca atacgctttc gactccattg
    22081 tagaaaaagg agttaaggga tctactgtaa gacaaattgc gaaattagct gatatgacac
    22141 ctggacagat tagatattat tttccgaatc attcagagtt attaaatgct gtaatgtcta
    22201 cagtagaatt aaaagtaagg aggagaattg aagcaatatt taaatctgaa aaccttacta
    22261 caatagataa agcaaaagcg agtttattaa cagtactacc attggataaa gagagactag
    22321 ctgatatgga agtttggatg gcgtttcgca atgacataca tgagtatggt caaagtacac
    22381 ttgatgatgg gttagatcaa ttatgtaata gtattttgac attattaaaa aacgatcatt
    22441 tgctgaagaa caatgtgaat attcatctta attcgatgaa attacatgca ttaattgacg
    22501 gtttagcttt
//
LOCUS       DAPDIM010000044        22385 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000044 DAPDIM010000000
VERSION     DAPDIM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 22385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22385
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.044"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..72)
                     /locus_tag="RFE25_001845"
     CDS             complement(<1..72)
                     /locus_tag="RFE25_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015063485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDU2816899.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRY"
     gene            126..497
                     /locus_tag="RFE25_001846"
                     /pseudo
     CDS             126..497
                     /locus_tag="RFE25_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016912861.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase family
                     protein"
     gene            1134..1877
                     /locus_tag="RFE25_001847"
     CDS             1134..1877
                     /locus_tag="RFE25_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase"
                     /protein_id="HDU2816900.1"
                     /translation="MLTVYGHRGLPSKAPENTIASFKAASEVEGINWLELDVAITKDE
                     QLIIIHDDYLERTTNMSGEITELNYDEIKDASAGSWFGEKFKDEHLPTFDDVVKIANE
                     YNMNLNVELKGITGPNGLALSKSMVKQVEEQLTNLNQNQEVLISSFNVVLVKLAEEIM
                     PQYNRAVIFHTTSFREDWRTLLDYCNAKIVNTEDAKLTKAKVKMVKEAGYELNVWTVN
                     KPARANQLANWGVDGIFTDNADKMVHLSQ"
     gene            1974..2402
                     /locus_tag="RFE25_001848"
     CDS             1974..2402
                     /locus_tag="RFE25_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC family dehydratase"
                     /protein_id="HDU2816901.1"
                     /translation="MKYDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAE
                     QSRFKGIIASGMHTLSISFKLWVEEGKYGEEVVAGTQMNNVKFIKPVYPGNTLYVIAE
                     ITNKKSIKKENGLVTVSLSTYNENEEIVFKGEVTALINNS"
     gene            complement(2448..4457)
                     /gene="mecA"
                     /locus_tag="RFE25_001849"
     CDS             complement(2448..4457)
                     /gene="mecA"
                     /locus_tag="RFE25_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP2a family beta-lactam-resistant peptidoglycan
                     transpeptidase MecA"
                     /protein_id="HDU2816902.1"
                     /translation="MMKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFK
                     QVYKDSSYISKSDNGEVEMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKI
                     KTNYGNIDRNVQFNFVKEDGMWKLDWDHSVIIPGMQKDQSIHIEKLKSERGKILDRNN
                     VELANTGTAYEIGIVPKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTV
                     KKMDEYLSDFAKKFHLTTNETESRNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDD
                     AVIGKKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQ
                     KSIYNNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYGMSNEEYNKLTEDKKEPL
                     LNKFQITTSPGSTQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVV
                     NGNIDLKQAIESSDNIFFARVALELGSKKFEKGMKKLGVGEDIPSDYPFYNAQISNKN
                     LDNEILLADSGYGQGEILINPVQILSIYSALENNGNINAPHLLKDTKNKVWKKNIISK
                     ENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGTAELKMKQGETGRQIGWFISYDKD
                     NPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENGNKKYDIDE"
     gene            4554..5540
                     /locus_tag="RFE25_001850"
     CDS             4554..5540
                     /locus_tag="RFE25_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer MecR1"
                     /protein_id="HDU2816903.1"
                     /translation="MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVL
                     VSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFET
                     SNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKK
                     HITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQ
                     LYVVFKMIFWFNPALYISKTMMDNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKS
                     QHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISSFT"
     gene            5512..5772
                     /locus_tag="RFE25_001851"
     CDS             5512..5772
                     /locus_tag="RFE25_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3387 domain-containing protein"
                     /protein_id="HDU2816904.1"
                     /translation="MYVVYRASHETAKEALGDKELRAIAHELTKTVKDNMSVDWSKRD
                     SAKAKMRVQVRRLLKKYGYPPDLQKMAVEQVVEQAELMASQQ"
     gene            complement(5763..7370)
                     /locus_tag="RFE25_001852"
                     /pseudo
     CDS             complement(5763..7370)
                     /locus_tag="RFE25_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274780.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(7422..7928)
                     /locus_tag="RFE25_001853"
     CDS             complement(7422..7928)
                     /locus_tag="RFE25_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HDU2816905.1"
                     /translation="MNTIKSTINTEAIFSDDEQHRYLLKKTWDEKKPACTVITMYPHL
                     DGVLSLDLTTVLILNQLANTEQYGAVYLVNLFSNIRTPENLKHIKNPYDEHTDIHLMK
                     AISESDTVILAYGAYAKRPVVIDRVEQVMEMLKPHKKKVKKLINPVTNEIMHPLNPKA
                     RQKWILKS"
     gene            complement(7943..8254)
                     /locus_tag="RFE25_001854"
     CDS             complement(7943..8254)
                     /locus_tag="RFE25_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816906.1"
                     /translation="MNINRYITRGISEHLSLDLQILLWNMVKERDNQPDTDYLHIFRL
                     KEDENILSIIHEQEQPTYKLEYHYTNYIKNQNALPKKVYVIREDDVDVFYYVMLLPEE
                     Y"
     gene            complement(8341..8691)
                     /locus_tag="RFE25_001855"
     CDS             complement(8341..8691)
                     /locus_tag="RFE25_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002502216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816907.1"
                     /translation="MKTTTQELKQYITRLFQLSNNETWECEALEEAAENILPTRFVDH
                     TPLAHLTLDTYTYYNDELHELSIYPFLMYTNNQLISIGYLDHFDMDFLYLTDTKNTII
                     DERHLLKEGGTRHE"
     gene            complement(9157..10781)
                     /locus_tag="RFE25_001856"
                     /pseudo
     CDS             complement(9157..10781)
                     /locus_tag="RFE25_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186610.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(10803..12152)
                     /locus_tag="RFE25_001857"
     CDS             complement(10803..12152)
                     /locus_tag="RFE25_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002486190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDU2816908.1"
                     /translation="MKQAIGYLRQSTTKQQSLAAQKQTIEALAKKHNIQYITFYSDKQ
                     SGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRNLKNALKLMKLCQKYHVHILSVH
                     DGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYHYH
                     NGTFTIDTVKAPTVKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYC
                     GRVINQYGQYENMFPAIVSTTIYEEAQVTRTQKPVKRKPSENQLKQKIKCPYCDSTLT
                     NMTIRKKHHTLRYYVCPQNMNASRFVCEFKGINAQELETSVLATCQDFFQNQQLYSKI
                     NHTIQQRLKRQRDIETKTTLNHEQLIEKLAQDKIDAETFREQTQSLRQQSKPISSIST
                     YQIRKAFQNIIQQRFTLNMLYPYIDEINISKNKSLAGIYFKNEPLNIVKQTMELSIV"
     gene            complement(12340..14109)
                     /locus_tag="RFE25_001858"
     CDS             complement(12340..14109)
                     /locus_tag="RFE25_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017176075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HDU2816909.1"
                     /translation="MSHHDIFRLGLYHLDTMGWHKTIPPKKDGDEKKVVTMSSCMAVE
                     AKFWHVLENTEKIIISNGKDKEHTFDSDILTTRKLPSLIKYGHSINENYIKDLSYALQ
                     LMRDEMPTSDLYDGSGIIETPHGYIVMIDTIYTSKQYDQLSSLDPIVDSAYPLEPKGT
                     FKDWLNMYINEVKGHLLLELAVVFGISALVTSFLKYKREIEFAGIIFSFTGQSSTGKS
                     TAAALAVSVAGNPTKGNQTLFRSWNATRNALESYLSNNFGIPIVFDELSSATFKDTTG
                     LLYSIAEGQGRQRSNVHGEVKTPKNWGTSVISTSEYSIFTDSAQNDGLRVRTIEINEQ
                     FTTNATNADNIKKAVALNHGHVLPLVAQYLINREDEVIQWFYKEVDWFEAKLNSETNN
                     TGIRMFKRYAVITTSAKILGRVLATDIDIAKIRDYFIDYHAHTVSERSLADKAIEVIT
                     QFVAQNRGKFSDDTALKNMFENYGLIALKDNHIEVKIIASVFKNMLLEHHFQDVNNVV
                     NALRDKGFIESDHDRITTKRTVKDGNGKKQSLVFYHLKLDSEYASIFGLTKDAEPIKA
                     EINLDNKKILESWKKQNDDLIDF"
     gene            complement(14109..14405)
                     /locus_tag="RFE25_001859"
     CDS             complement(14109..14405)
                     /locus_tag="RFE25_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDU2816910.1"
                     /translation="MSYKQEDDFKKLKNRILGISINLPEGQTFTFHDLNRRANVQCSK
                     AVQQNVGRWFAYFVKQAPRVPFIIIGKNTNGHLVYMKVGPNPLNDSNPSKGGVR"
     gene            14576..16153
                     /locus_tag="RFE25_001860"
     CDS             14576..16153
                     /locus_tag="RFE25_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816911.1"
                     /translation="MYDFLEYLHRYCIKSINNWEAVADISCKVERGNVSTGYYVKQDR
                     IVIDDSDIPPIIKISGSYIAADILVTRYLDGMGEFIKVSKLDQSSYYEWFMFVEETRR
                     IFRGTEIVYQFLKYLFTHTYEHKNEEKRIEKHMKNIIIDNQFRGQHINDIVRLDMKDD
                     NMLFYNFDIYDTNVLYKEIDEEKLLRILDEISNTDNYKALFNIISENQKKFWKSNIKP
                     IVSECSDGINTTTFDLYAYVNKYISNKIFDCDNYLITKNEVVDFYFNHGSDFNNFKMG
                     QTGTKSKFKQGNKLKIHEYIIAVTYVNLLNHSYMKYINAESYYDPSKKIIKGMKNDYH
                     KFTDSFSDFVEMVDDITWRIRDSFDYIGGLKNKEISEDENEYIEQLIQFVILSKFGYM
                     NVENHFNYIENLNTLNNELTTILRSEFAHISNDMYNNLFGNLFDVVNTWKKDYSNNFY
                     NNTQNTIPTEKLDIISSFIKQYDKPIERDEHGKHVKAKVFEGISDFHKRVKKGFDNND
                     VLLHLRLEMSVHENKYD"
     gene            complement(16233..17561)
                     /gene="cstB"
                     /locus_tag="RFE25_001861"
     CDS             complement(16233..17561)
                     /gene="cstB"
                     /locus_tag="RFE25_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002488497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="persulfide dioxygenase-sulfurtransferase CstB"
                     /protein_id="HDU2816912.1"
                     /translation="MFFKQFYDKHLSQASYLIGCQKTGEAMIIDPIRDLSSYIRVADE
                     EGLTITHAAETHIHADFASGIRDVAIKLNANIYVSGESDDTLGYKNMPNHTHFVQHND
                     DIYVGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEK
                     AVKVEGSSEIGAKQMFKSIESIKDLPDYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQ
                     TNWAFSENNEATFIDKLISDQPAPPHHFAQMKKINQFGMNLYQPYTVYPATNTNRLTF
                     DLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYDQEINLIGDYHLVSKATHTLQLI
                     GYDDIAGYQLPQSKIQTRSIHSEDITGNESHILDVRNDNEWNNGHLSQAVHVPHGKLL
                     ETDLPFNKNDVIYVHCQSGIRSSIAIGILEHKGYHNIINVNEGYKDIQLS"
     gene            complement(17580..18647)
                     /locus_tag="RFE25_001862"
     CDS             complement(17580..18647)
                     /locus_tag="RFE25_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/DsrF/DrsH-like family protein"
                     /protein_id="HDU2816913.1"
                     /translation="MSQYKTKHINDFTKKELQELSSKGQLIDVRHPEEFELGHIKNAL
                     LHSVENIETFKQSKNKTYYIYCKSGNRSRKASQFLAQRGYDVVNLDGGYTAYEQQHHN
                     DNLSKVKEDREIKDNRKTFNYSNLQCPGPIVNISKEIKNIAIGDQIEVVVTDHGFLND
                     IKSWVKQTGHTLVRLNDFGNEIRAIIQKEENKNIEVTHTKSGTTIVLFSGELDKAVAA
                     MIIANGAKAAGRDVTIFCTFWGLNALKKIQSQRIKKKGIAKLFDFMLPNSPINMPISK
                     MNMFGLGNLMMRYVMKKKNVDTLPSLIDQAVEQGVKLIACTMSMDVMGITKEELRDDV
                     EYGGVGAYIGYTEQANHNLFI"
     gene            18786..19046
                     /gene="cstR"
                     /locus_tag="RFE25_001863"
     CDS             18786..19046
                     /gene="cstR"
                     /locus_tag="RFE25_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="persulfide-sensing transcriptional repressor
                     CstR"
                     /protein_id="HDU2816914.1"
                     /translation="MEYNKKMINRIHRIQGQLNGVIKMMEEEKNCKDVISQLSASKSS
                     IQRLMGIIISENLVECVKMSEENSEDSQALINEAVELLIKSK"
     gene            19043..19801
                     /locus_tag="RFE25_001864"
     CDS             19043..19801
                     /locus_tag="RFE25_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDU2816915.1"
                     /translation="MISITVIIVMLVIGILGGFISGLVGIGGAIVIYPALLLLPPLFG
                     LPTYSAYIASGLTSSQVFFSTLSGSLKAYKNKNFSRTLILNMGSGMVIGSILGALLAT
                     VFNSQFVNVIYIIIALLALILMFIKVTPSTSHIKFNRVLLITIGGIIGLVSGIVGAGG
                     AFIIIPVLLVIFKLPMNMVVTNSIVIAFISSIGAFIIKLLQGYIPINSAIPLILGSIL
                     FTPLGMKIGQKIPDSIQKGIVSILIVIAIIKLIF"
     gene            20017..>22385
                     /locus_tag="RFE25_001865"
     CDS             20017..>22385
                     /locus_tag="RFE25_001865"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019142.1,HMM:NF028351.1,HMM:NF037833.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="E domain-containing protein"
                     /protein_id="HDU2816916.1"
                     /translation="MNKNSKKKLDFLPNKLNKYSIRRFTVGTASILVGATLIFGVAND
                     QAEAAENNTTQKQDDSSDASKVKGNVQTIEQSSANSNESDIPEQVDVTKDTTEQASTE
                     EKANTTEQASTEEKADTTEQATTEEAPKAEGTDKVETEEAPKAEETDKATEEAPKTEE
                     TDKATTEEAPKAEETDKATEEAPKTEETDKATTEEAPAAEETSKAATEEAPKAEETSK
                     AATEEAPKAEETEKTATEEAPKTEETDKVETEEAPKAEETSKAATEKAPKAEETNKVE
                     TEEAPAAEETNKAATEETPAVEDTNAKSNSNAQPSETERTQVVDTVAKDLYKKSEVTE
                     AEKAEIEKVLPKDISNLSNEEIKKIALSEVLKETANKENAQPRATFRSVSSNARTTNV
                     NYSATALRAAAQDTVTKKGTGNFTAHGDIIHKTYKEEFPNEGTLTAFNTNFNPNTGTK
                     GALEYNDKIDFNKDFTITVPVANNNQGNTTGADGWGFMFTQGNGQDFLNQGGILRDKG
                     MANASGFKIDTAYNNVNGKVDKLDADKTNNLSQIGAAKVGYGTFVKNGADGVTNQVGQ
                     NALNTKDKPVNKIIYADNTTNHLDGQFHGQRLNDVVLNYDAATSTITATYAGKTWKAT
                     TDDLGIDKSQKYNFLITSSHMQNRYSNGIMRTNLEGVTITTPQADLIDDVEVTKQPIP
                     HKTIREFDPTLEPGSPDVIVQKGEDGEKTTTTPTKVDPDTGDVVERGEPTTEVTKNPV
                     DEIVHFAPEEVPQGHKDEFDPNLPIDGTEEVPGKPGIKNPETGEVVTPPV"
BASE COUNT         7429 a         3416 c         3728 g         7812 t
ORIGIN      
        1 atatcttaga tagtagccaa cggctacagt gataacatcc ttgttaaatt gtttatatct
       61 gaaatagttc atacagaaga ctcctttttg ttaaaattat actataaatt caactttgca
      121 acagaaccgt attatggaat agagatgttg gtaacattta tacaggatca ttatacttaa
      181 gtttaatttc gttattacag aaccacacat tccaaccaga agagaaagta tgtctattta
      241 gttatggttc aggagcagta ggagaaatct ttagtggttc aatcgttaaa ggatatgaca
      301 aagcattaga taaagagaaa cacttaaata tgctagaatc tagagagcaa ttatcagtcg
      361 aagaatacga aacattcttt aacagatttg ataatcaaga atttgatttc gaacgtgaat
      421 tgacacaaga tccatattca aaagtatact tatacagtat agaagaccat atcagaacat
      481 ataagataga gaaataaact agtggccgat tgtgcttgat gagcttggga cataaatcct
      541 aactcgaaat aaataagcat atcactaaac tgatttttta aagtttacag tgatatgctt
      601 atttttttat cttacgattt tgtacgtgca tgcttgccta ggggtatggc tcgagccatt
      661 agtctctcgc acatactatt ccctcaggcg tcagcactta caaaatcggt tgtaattttc
      721 atttttatac gcattcttac tgagattata ctaataagag gaatagtaaa agcaattcta
      781 agtaaaattg cagataagag gtacgttaaa agcagttcta ggcaaaattg cagataagag
      841 gtgcgttaaa agcagttctc agtaaaattg ctgataaggg gtaagttaaa agcaatccta
      901 agtaaaattg cagataaggg gtacagaaaa actagacttg attacaaaat ggagcttggg
      961 acataaatga ttttttaaaa atgagatgag acgtagatta actccataat caatacgaat
     1021 ctatcgactt ctttatttat gatattcatc tctttttaat ggaaataaaa gtgcgattaa
     1081 tgtgataata cagttacgtt aattaaaaaa ataaaaatgc aaggagaggt aatatgctaa
     1141 ctgtatatgg acatagagga ttacctagta aagctccgga aaatacaatt gcatcattta
     1201 aagctgcttc agaagtagaa ggtataaact ggttggagtt agatgttgca attacaaaag
     1261 atgaacaact gattatcatt catgatgatt atttagaacg gactacaaat atgtccgggg
     1321 aaataactga attgaattat gatgaaatta aagatgcttc tgcaggatct tggtttggtg
     1381 aaaaattcaa agatgaacat ttgccaactt tcgatgatgt agtaaaaata gcaaatgaat
     1441 ataatatgaa tttaaatgta gaattaaaag gtattactgg accgaatgga ctagcacttt
     1501 ctaaaagtat ggttaagcaa gtggaagaac aattaacaaa cttaaatcag aatcaagaag
     1561 tgctcatttc aagctttaat gttgtgcttg ttaaacttgc agaagaaatc atgccacaat
     1621 ataacagagc agttatattc catacaactt cgtttcgtga agactggaga acacttttag
     1681 attactgtaa tgctaaaata gtaaacactg aagatgccaa acttactaaa gcaaaagtaa
     1741 aaatggtaaa agaagcgggt tatgaattga acgtatggac tgtaaacaaa ccagcacgtg
     1801 caaaccaact tgctaattgg ggagttgatg gtatctttac agacaatgca gataaaatgg
     1861 tgcatttgtc tcaatagaaa gttagaggtg agtcttacgt ttcagtgacg gtagacttac
     1921 ctttaacatg ttacatacta aaaaattaat ttgaataaga aagagagaca tatatgaaat
     1981 acgatgattt tatagtagga gaaacattca aaacaaaaag ccttcatatt acagaagaag
     2041 aaattatcca atttgcaaca acttttgatc ctcaatatat gcatatagat aaagaaaaag
     2101 cagaacaaag tagatttaaa ggtatcattg catctggcat gcatacactt tcaatatcat
     2161 ttaaattatg ggtagaagaa ggtaaatacg gagaagaagt tgtagcagga acacaaatga
     2221 ataacgttaa atttattaaa cctgtatacc caggtaatac attgtacgtt atcgctgaaa
     2281 ttacaaataa gaaatccata aaaaaagaaa atggactcgt tacagtgtca ctttcaacat
     2341 acaatgaaaa tgaagaaatt gtatttaagg gagaagtaac agcacttatt aataattcat
     2401 aataaaacag tgaagcaacc atcgttacgg attgcttcac tgttttgtta ttcatctata
     2461 tcgtattttt tattaccgtt ctcatatagc tcatcataca ctttacctga gattttggca
     2521 ttgtagctag ccattccttt atcttgtaca tctttaacat taatagccat catcatgttt
     2581 ggattatctt tatcatatga tataaaccac ccaatttgtc tgccagtttc tccttgtttc
     2641 attttgagtt ctgcagtacc ggatttgcca attaagtttg cataagatct ataaatatct
     2701 tctttatgtg ttttatttac gacttgttgc ataccatcag ttaatagatt gatattttct
     2761 ttggaaataa tatttttctt ccaaactttg tttttcgtgt cttttaataa gtgaggtgcg
     2821 ttaatattgc cattattttc taatgcgcta tagattgaaa ggatctgtac tgggttaatc
     2881 agtatttcac cttgtccgta acctgaatca gctaataata tttcattatc taaatttttg
     2941 tttgaaattt gagcattata aaatggataa tcacttggta tatcttcacc aacacctagt
     3001 tttttcatgc ctttttcaaa tttcttactg cctaattcga gtgctactct agcaaagaaa
     3061 atgttatctg atgattctat tgcttgtttt aagtcgatat taccatttac cacttcatat
     3121 cttgtaacgt tgtaaccacc ccaagattta tctttttgcc aacctttacc atcgatttta
     3181 taacttgttt tatcgtctaa tgttttgtta tttaacccaa tcattgctgt taatattttt
     3241 tgagttgaac ctggtgaagt tgtaatctgg aacttgttga gcagaggttc ttttttatct
     3301 tcggttaatt tattatattc ttcgttactc atgccataca taaatggata gacgtcatat
     3361 gaaggtgtgc ttacaagtgc taataattca cctgtttgag ggtggatagc agtacctgag
     3421 ccataatcat ttttcatgtt gttataaata ctcttttgaa ctttagcatc aatagttagt
     3481 tgaatatctt tgccatcttt tttctttttc tctattaatg tatgtgcgat tgtattgcta
     3541 ttatcgtcaa cgattgtgac acgatagcca tcttcatgtt ggagcttttt atcgtaaagt
     3601 ttttcgagtc cctttttacc aataactgca tcatctttat agcctttata ttctttttgt
     3661 tttaattctt cagagttaat gggaccaaca taacctaata gatgtgaagt cgcttttcct
     3721 agaggatagt tacgactttc tgtttcatta gttgtaagat gaaatttttt tgcgaaatca
     3781 cttaaatatt catccatttt tttaacggtt ttaagtggaa cgaaggtatc atcttgtacc
     3841 caattttgat ccatttgttg tttgatatag tcttcagaaa tacttagttc tttagcgatt
     3901 gctttataat cttttttaga tacattcttt ggaacgatgc ctatctcata tgctgttcct
     3961 gtattggcca attccacatt gtttcggtct aaaattttac cacgttctga ttttaacttt
     4021 tcaatatgta tgctttggtc tttctgcatt cctggaataa tgacgctatg atcccaatct
     4081 aacttccaca taccatcttc tttaacaaaa ttaaattgaa cgttgcgatc aatgttaccg
     4141 tagtttgttt taattttata ttgagcatct actcgttttt tatttttaga tacttttttt
     4201 attttacgat cctgaatgtt tatatcttta acgcctaaac tattatatat ttttatcgga
     4261 cgttcagtca tttctacttc accattatcg cttttagaaa tataactgct atctttataa
     4321 acttgtttga aatttttatc ttcaattgca tcaatagtat tattaatttc tttatctttt
     4381 gaagcataaa aatatatacc aaacccgaca actacaacta ttaaaataag tggaacaatt
     4441 tttatctttt tcatcaatat cctccttata taagactaca tttgtagtat attacaaatg
     4501 tagtatttat gtcaaaataa tgttataatt tttgtgatat ggaggtgtag aaggtgttat
     4561 catctttttt aatgttaagt ataatcagtt cattgctcac gatatgtgta atttttttag
     4621 tgagaatgct ctatataaaa tatactcaaa atattatgtc acataagatt tggttattag
     4681 tgctcgtctc cacgttaatt ccattaatac cattttacaa aatatcgaat tttacatttt
     4741 caaaagatat gatgaatcga aatgtatctg acacgacttc ttcggttagt catatgttag
     4801 atggtcaaca atcatctgtt acgaaagact tagcaattaa tgttaatcag tttgagacct
     4861 caaatataac gtatatgatt cttttgatat gggtatttgg tagtttgttg tgcttatttt
     4921 atatgattaa ggcattccga caaattgatg ttattaaaag ttcgtcattg gaatcgtcat
     4981 atcttaatga acgacttaaa gtatgtcaaa gtaagatgca gttctacaaa aagcatataa
     5041 caattagtta tagttcaaac attgataatc cgatggtatt tggtttagtg aaatcccaaa
     5101 ttgtactacc aactgtcgta gtcgaaacca tgaatgacaa agaaattgaa tatattattc
     5161 tacatgaact atcacatgtg aaaagtcatg acttaatatt caaccagctt tatgttgttt
     5221 ttaaaatgat attctggttt aatcctgcac tatatataag taaaacaatg atggacaatg
     5281 actgtgaaaa agtatgtgat agaaacgttt taaaaatttt gaatcgccat gaacatatac
     5341 gttatggtga atcgatatta aaatgctcta ttttaaaatc tcagcacata aataatgtgg
     5401 cagcacaata tttactaggt tttaattcaa atattaaaga acgtgttaag tatattgcac
     5461 tttatgattc aatgcctaaa cctaatcgaa acaagcgtat tgttgcgtat attgtatgta
     5521 gtatatcgag cttcacatga aacagctaaa gaagctttgg gcgataaaga gttaagagcc
     5581 attgcacatg agttaactaa aacagttaag gataacatga gtgttgattg gtctaaacga
     5641 gacagtgcta aagctaaaat gagagttcaa gttagacgcc tattaaagaa atatggctat
     5701 ccaccagatc ttcaaaaaat ggctgtggaa caagttgtag agcaagcaga attaatggca
     5761 agtcagcaat aaaaaaataa atcataatga gtccgggaca taaagttctt ggataagtga
     5821 aaaaagacaa tttctattga aataatatag aaattgtctt ttttataaat tttttgatta
     5881 ttttcagctc gttgagctac tacttttctt atattaagtg ccattaatac aaaaccaagt
     5941 tctcttttga ctttattgag tcctcggaca gacatccgag tgaaacccaa aatagccttc
     6001 ataaatccaa aaacaggttc cacatcaatt tttctttgat tgtagatatt ttttgtttct
     6061 ggttctgaaa gctttttgtt aatttgggat ttaaaatatt cccagttata attcttcatt
     6121 atttttttgt ttgtttttga attgaagttc atacattgat ttttcagagg acattctgaa
     6181 caatcatcac attcatataa tttgaagtct cgcttataac catacttatc atgacgatag
     6241 gcatatcttt taaaacctag ccgtttatta ttcggacaaa tgaattcgtc attaatttcg
     6301 tcatagttcc aattttgagt attaaagatg tcacttttat attttttagt tttatctttt
     6361 ataaacattc catatgttat gagtggcgtt cgattaaagt catctataat tgccttataa
     6421 tttgattcac taccataacc tgcatcagct acaatatatt caggtaaatg accgtaggtc
     6481 tcttgaattg aatttaaaaa tggaatcatc gttctagtat ccgttggatt ttgatacaca
     6541 ttataagata aaacaaattg ggaatttgtt gctatttgta aattataccc tggcttaagt
     6601 tgtccatttt tcatgtgatc ttctttcatt ctcataaatg tcgcatcata atctgtctta
     6661 gaataactat ttctatcctt taaaatagat ttttgaaatt cgtatcgata ctttcgctca
     6721 aaataatcat tgatttgctt tttgtatttt ttgattttag ttcttttgag acgtatttgt
     6781 tttcttgttt tagtacattt ttcattgttg atatgttggt ttaaatcttc gatttcttta
     6841 tctaagtgac taccaatcaa atctatttct tcttttgtta attcattatc atgatcttct
     6901 ttaatttccg gtatgatttt attggttacc aattcatggt agagggcttt agaatcctca
     6961 ttcatctttg attcatggtt ttgaatactc tttttccata caaatgtata tcgattggca
     7021 tttgcttcaa tttttgtacc atcaataaaa atagctttat catctataag attttgtttt
     7081 acacactgac tgtaaaattg aataaataaa gattctaata aagcatctac ttttggattt
     7141 actctaaatt gattaattgt tttataagaa ggtttttgat tttgtgatag ccacatcatt
     7201 cggatgctat cattaagcat tttttctatt ttacgacctg agaatacaga ttgtgtgtag
     7261 gcatatagaa tcacttttaa catcatttta ggatggtacg aagttgcacc acggtgatgt
     7321 ctgaattcgt cgaattcatt gtcaggaatt gtttcaacaa tatcatttac agtaaaacga
     7381 tgttgatttg ttttgtttcc atattgacct ccatgtattt gctatgattt caaaatccat
     7441 ttttgacgtg ccttagggtt gagtggatgc ataatttcat ttgttactgg attgatgagc
     7501 ttttttactt tctttttatg aggttttaac atttccatca cttgttcgac acggtcgata
     7561 acaactggtc gcttcgcata ggcaccataa gcaagaatca ctgtgtcact ttcactaatc
     7621 gctttcatca aatgaatatc agtgtgctca tcgtatggat ttttgatatg tttgaggttt
     7681 tcgggtgttc taatatttga aaatagattt acaagatata cagcaccata ttgttcagta
     7741 ttagctaatt gattgaggat aagaacagtt gtgagatcga gtgataatac accatctaaa
     7801 tgagggtaca tcgttatcac tgtacaagcg ggtttctttt catcccatgt tttcttgagt
     7861 aaatagcggt gttgttcatc atcgctaaat atggcttctg tgtttatcgt acttttgatt
     7921 gtattcatca tcgtcactcc ttttagtatt cttctggtaa aagcatcaca taataaaaaa
     7981 catctacatc atcttctcgg atgacgtaga ctttcttagg taatgcattt tgatttttta
     8041 tatagtttgt atagtgatat tccaatttgt acgtgggttg ttcttgctca tgtatgattg
     8101 aaagtatatt ctcatcttct ttcagtctaa aaatgtgtag gtaatctgta tcaggttgat
     8161 tatctctttc ttttaccatg ttccaaagta agatttgaag atctagagat aggtgttcac
     8221 taatgcctct tgtgatatat cgattgatgt tcatactatt ttcctccatt ttgcttttct
     8281 ttcatgatgt caatcacttc gttaatgact gtaacagata tttgtgccac tttgatccaa
     8341 ttattcatgg cgagtccctc cttcttttag tagatgacgt tcatcgataa tcgtattttt
     8401 agtatctgtg agatataaaa agtccatgtc aaaatgatcc agataaccga tactgatgag
     8461 ttggttattg gtgtacatta gaaatggata gatacttagc tcatgtagct catcattata
     8521 gtaggtataa gtgtcaagtg taagatgcgc aagtggggta tggtctacaa agcgagtagg
     8581 aagtatattt tctgctgctt cttctaacgc ttcacattcc catgtttcat tgttagatag
     8641 ttggaataga cgagttatat attgtttgag ttcttgagtg gttgttttca tatcattgcc
     8701 tcctagatag tgttagcgat gtatttcata tacatcactg agataatata tatttgattt
     8761 atcatttatt acgaatcccg gtgggaataa gagaaaatcc catatgaaaa actgctacaa
     8821 acattgatat gacaagaaaa tcccgttatc ccgctcattt gttgggaaat atagctatat
     8881 atttatatat catttggatt tggtggtgtt attacgactt actttttctt tttatattat
     8941 ttatttataa ataataacgg gattttggga ttacgcttgc gtaatccttc tcctacatga
     9001 agttagccaa tcccgttact atcccactta tattttgttt tgggatgttc tttcgtcata
     9061 tcaatataag cttcacattg agccatgatt tgttagcgtg ttgaatatat ttgttagatg
     9121 agtgttattg aatgacgaaa ggacagtaca tagatattat atttgaaagt agagtgtttg
     9181 aggcaaaaac aaagacgaag tgctgagaag cacttcgtct agattattat tattgaaaag
     9241 ttgtttaata atttcattat taagttttag tgtaacaaag aattgctttt tatgattctc
     9301 atctttacga atgtcaatac ggtcaataac cgttaggtac aaagctttga gctgtgattt
     9361 atccatggat tctatatttt gaaatattcg ttgtaataaa gcagcgattt gtttagtatc
     9421 ataaaatggt ttctcttgat tttgttggtg cttgagttga ttaatttggt ttgtgatatc
     9481 attcagttgt gtttcatatt gatgaatggt tggtttgagt gcagatgtta agtctggatt
     9541 gtcttcgatg gtttgaatta gatttttaag tttagtgcta atttcatcaa attgttgttg
     9601 tttataagca atatcatggt taagtgcagc tacatcgact tgattctctt gattgacacg
     9661 ttcgacaact tgtttgagaa ctttatcact tttgacaatt tcaagtattt ggtccataac
     9721 atatttttca atgacatcgg ctctaacact attcgcagaa catacctttg agcctttatt
     9781 tcgaaaatta ctacacgaat agtaacgaat acgtttttag tgccatcttt aagtgtgttt
     9841 gtggtgttac tcgcagccat aggtgcagaa cattggggac acgaaattat tccagttaaa
     9901 atattggttc ctttaccatg gacttgtggt ttttcactta cttgtttctt acgtgcttgc
     9961 actttatccc ataatgattg actaataata ggcgtgtgtt taccttcagc gattactggc
    10021 ttatcgttta atcctttacg tcgtttatca ttccaatctt tgtatttcgc gaattgaatt
    10081 ttaccaatat agaatgggtt tgagagaata taagtaacag ctgaaatact aaatggattg
    10141 ccttttttag tcacatagcc tttgtgattg aatgcattgg ctattttacg ataaccatga
    10201 cctttggcat aagattcaaa gatatattta acgatgttag cttcatgttg attaatcatt
    10261 aattcttttt tattatcagg tatgttatta tatcctaatg gaagattgcc ttgataatag
    10321 ccctctaaag ctctttgacg ttgtcaggtg taaatattct ctaaaattgt atttctttcg
    10381 aattcggaaa aacttgcaag tatctggagc attaacttgc ctgttgaatt tttgacttcc
    10441 atacgttcag acaagctaaa aaattcaaca ttttggcgat gaagttcttc gactattgta
    10501 agtaaatcgg aagtattacg tgccaaacga tttgttttat aaaccataac acagtctaat
    10561 tttccatttt tagcatcatt taacatgcgc tgtaattcag gacggttcat agattttcct
    10621 gatatacccc gatctgcata tatatcaaca agttcatagc cgttaaattg gcaatattgc
    10681 tctatttgtg taatttgtcc ctctatgcta taaccttcta cttgtctctc tgtggacaca
    10741 cgaatgtagc ctcctacaag ctttttcttc attttatcca ttataatcca tcctttcttt
    10801 aattatacaa ttgataattc catagtctgc tttacaatat tcagtggttc atttttgaaa
    10861 tagatgccag cgaggctttt atttttagaa atattaattt catcaatata ggggtacaac
    10921 atgtttagcg tgaaacgttg ttgaatgatg ttttggaaag cttttcgaat ttgatacgta
    10981 ctgattgatg atataggttt tgattgctga cgtaatgatt gcgtttgttc tctgaacgtt
    11041 tctgcatcaa ttttgtcttg ggctaatttt tctatcagct gctcgtgatt gagtgtagtt
    11101 ttagtttcta tatctctttg tcttttgagt cgttgttgaa tagtatggtt tatttttgaa
    11161 tagagctgtt gattttgaaa gaagtcctga caagtcgcta aaacacttgt ttctaattct
    11221 tgtgcgttga tccctttgaa ttcacagaca aaacgagatg cattcatatt ttgaggacaa
    11281 acataataac gtaatgtatg gtgctttttt ctaatggtca tattagttag tgttgaatca
    11341 caataaggac atttgatttt ttgtttgagt tggttttctg acggcttacg ttttactggt
    11401 ttctgagttc gggtaacttg agcttcttcg tatatcgttg tactgacaat agctgggaac
    11461 atgttttcat attgtccgta ttgattgata acacggccac agtaattagg gttaaggata
    11521 atattacgca cttgataggg cttacgatta atgaatttat catcagcttc taagtattgc
    11581 gcaatttttt tataaccata accttgaagg taataattga acacagcttt tactgttggt
    11641 gcttttactg tgtctatcgt gaaagtacca ttatgatagt gatacccaaa gggtgcatgt
    11701 gttgtaatca ttttaccttg tttcgctttt tctttgattc catttttgac ttgttcgcct
    11761 atattatcag attctagttc ggccaagctg atgaaaatat tgagtttgag ccgatcgaat
    11821 gctttatcca tatcaaaata gccatcatga acgcttaaga tatggacatg gtatttttga
    11881 cacaatttca tgagttttaa tgcattttta agattgcgat gaagtcggtt taatctgtaa
    11941 caacataata catcacattg tccttgttga atcagttcag taatttgttg gtaaccgttc
    12001 cgcttatcag tgcgtcctga ttgcttatcg ctataaaagg taatgtattg aatattatgt
    12061 tttttggcta atgcctcgat ggtttgtttt tgtgctgcta aggattgttg ctttgtagtg
    12121 ctctgtcgta agtaacctat tgcttgtttc atcgtatttc ctccttccaa agtgataata
    12181 tatatttatg aacgaattta tagatgagcc caacacctgc tggtgttggg cgttattatt
    12241 agtcatcagc atgattaatt tcttcaaaaa ctaaatcagc tagtaattca atcaattcat
    12301 ccattttatt cactcctgta cgatttcatc tttaagttat taaaaatcaa ttaaatcatc
    12361 attctgtttt ttccatgatt caagtatctt tttgttatcc aagttaattt cagctttaat
    12421 aggttcagca tctttagtta gaccaaaaat agacgcatat tctgaatcta gctttaaatg
    12481 gtaaaagaca agtgactgtt ttttgccatt gccatctttg actgttcttt ttgttgtaat
    12541 tcgatcatgg tcagattcga taaatccttt atcccttagc gcattaacaa cattattaac
    12601 atcttggaag tgatgctcta acaacatatt tttaaataca gacgcaatga ttttgacttc
    12661 gatatgatta tcttttaagg caattagtcc atagttctcg aacatattct ttaacgctgt
    12721 atcatcagaa aatttaccac ggttttgtgc tacaaattga gtaatgactt cgatcgcttt
    12781 atctgccagt gatcgttcag agactgtatg agcatgataa tcaataaagt agtctctgat
    12841 tttagcgata tcaatatctg tagctaaaac acgacctaat attttcgcag atgttgtaat
    12901 gactgcataa cgcttaaaca tacgaatacc tgtattgttt gtttcactgt tcaatttagc
    12961 ttcaaaccaa tctacttcct tgtaaaacca ttgaataact tcatcttcac gatttataag
    13021 gtattgagct actaacggta aaacatgacc atggtttagt gccacagctt ttttgatatt
    13081 gtcagcattg gtcgcatttg tagtaaattg ttcattaatc tcgatggttc ttacacgtaa
    13141 tccatcgttt tgagcagaat cagtaaagat actgtattca gaggttgaaa tcacagaagt
    13201 gccccaattc ttaggcgttt taacttctcc gtgtacattg gaacgttgac gcccttgacc
    13261 ttcagcgata gagtacaata accccgttgt atctttaaaa gttgctgatg agagttcatc
    13321 aaatacaata ggtataccaa aattgttact caagtaactt tcaagtgcat tacgtgtggc
    13381 attccaactt cgaaaaagtg tttgattacc tttagttgga tttccagcga cggatactgc
    13441 taaagctgct gctgttgatt taccagttga tgactggcct gtaaaactaa agataattcc
    13501 tgcaaattcg atttcacgtt tgtacttcag aaagcttgtc actaaggcag aaattccaaa
    13561 tacgaccgct aactctagaa gaagatgacc tttgacttcg ttaatataca tatttaacca
    13621 atctttaaat gtacctttag gctctaatgg ataagcacta tcgacaatag gatctaaaga
    13681 tgataattga tcatattgtt tagatgtata aatggtatct atcattacaa tataaccgtg
    13741 gggtgtttct atgatgcccg agccatcata taaatcagaa gtgggcattt catcgcgcat
    13801 taattgtagt gcatagctca aatcttttat ataattttca ttgatactgt gaccatattt
    13861 aatcaaggaa ggtaactttc gagttgttaa aatatcagag tcaaatgtat gttctttatc
    13921 cttaccgtta gaaataatta ttttttctgt attttctaag acatgccaaa atttagcttc
    13981 aacagccata caactagaca tagtcactac ttttttctca tctccatctt ttttaggtgg
    14041 gatagtttta tgccaaccca ttgtatctaa atggtatagg cctagtctaa aaatgtcatg
    14101 atgactcatt agcgaacacc tcctttcgaa gggttgctat cattgagtgg attaggtccg
    14161 actttcatat atactaaatg accattggta tttttaccga taataataaa tggaacacgt
    14221 ggcgcttgtt ttacaaaata tgcgaaccaa cgtccaacat tttgttgtac agcttttgag
    14281 cattgtacat ttgcacgacg gttcaagtca tggaaagtaa atgtttgtcc ttctggtaaa
    14341 ttaattgaaa tacctaaaat tctatttttt aattttttaa aatcatcttc ttgcttgtaa
    14401 gacatttgaa ttcctcctaa atattattaa ttaattctat cttctggcta tttcagaaga
    14461 ttacattgct tataatagag gtgtactgtt tttattgctc gaatagtatt gagcaaaaga
    14521 cgaacacata aatgcaagcc tttttgcttg acaaattaga aaagaggtaa acaaagtgta
    14581 tgatttttta gaatacttac atcgttattg tataaaatca attaataatt gggaggctgt
    14641 tgcagacata tcatgcaaag ttgaacgtgg aaatgttagt acgggctatt atgttaaaca
    14701 agatagaatt gtaatagatg atagtgatat acctccaatt attaaaataa gtggaagtta
    14761 tatagcagca gacatattag ttactagata tttagatgga atgggtgaat ttataaaggt
    14821 atcaaaatta gatcaatcga gctattacga atggtttatg tttgttgaag aaacgagaag
    14881 aatatttaga ggtacagaaa tagtttatca atttttaaaa tatctattta cgcataccta
    14941 tgaacataaa aatgaagaaa aaagaataga aaaacatatg aaaaacatta tcatagataa
    15001 tcaatttaga gggcagcata tcaatgatat cgttcgttta gacatgaaag atgataatat
    15061 gttattttac aattttgata tatacgatac aaatgttctt tataaagaaa tagacgagga
    15121 aaaattactt agaattttag atgaaataag taatactgac aattacaaag cgctatttaa
    15181 cattataagt gagaatcaaa agaaattttg gaaatcaaat attaaaccaa ttgtaagtga
    15241 atgttcagat ggtataaata caaccacatt tgatttatat gcttatgtaa ataagtatat
    15301 aagtaataaa atatttgact gtgataatta tttaattact aaaaatgagg ttgtggattt
    15361 ctattttaat catggtagtg actttaataa tttcaagatg ggacagacag gcacaaagtc
    15421 caaatttaag cagggaaata aacttaaaat acacgaatat atcattgcag taacttatgt
    15481 aaatttatta aatcattcat atatgaaata tatcaatgct gaaagttact atgaccctag
    15541 caaaaaaata ataaaaggaa tgaaaaatga ttatcataaa tttacagatt cattcagtga
    15601 ttttgtagaa atggtggacg atataacatg gagaatccgt gattcgtttg attatattgg
    15661 aggattaaaa aataaagaaa ttagcgaaga tgagaacgaa tatatcgaac aattaattca
    15721 atttgttata ttatctaaat tcggctatat gaatgtggaa aatcatttta attatattga
    15781 gaacttaaat acacttaata acgaattaac gactatatta agaagtgaat tcgcgcacat
    15841 ttcaaatgat atgtataata atttatttgg taatttattc gatgttgtaa atacatggaa
    15901 aaaagattat tcaaataatt tttataataa tactcagaat actataccta cagaaaaatt
    15961 agatataata tcttcattta taaaacaata tgataaacca attgaacgag acgaacatgg
    16021 caaacacgtt aaagcaaaag tgtttgaagg tataagtgat tttcataagc gtgtaaaaaa
    16081 aggatttgat aataatgatg tgctattgca tttgagattg gaaatgagtg tacatgaaaa
    16141 taagtatgat taactactag tttatccaat aatataaaaa ggactataag ctatatctaa
    16201 atacttatag tccttcttca ttagtataaa tattaagaaa gttgtatatc tttataacct
    16261 tcatttacat taataatgtt gtgataacct ttgtgttcta aaataccaat agctatcgaa
    16321 cttctaatgc cagactgaca gtgtacataa ataacatcgt ttttattgaa aggtaaatct
    16381 gtttctaaaa gtttgccgtg tggtacatga accgcttgag ataagtggcc attattccat
    16441 tcattatcat tacgtacatc taatatatgt gattcgttac ctgtaatgtc ttcactatga
    16501 atggaacgtg tttgaatctt agattgcggt aattgatatc cagcaatatc atcgtatcca
    16561 atgagttgta aggtgtgtgt tgcttttgaa acaaggtgat agtctccaat caagttaatt
    16621 tcttgatcat agtttagata ccagccaatt tgattgatga aatttttatc atatggaata
    16681 ttgattgtac cttcaatatg tccaccatga taagcctcct tactgcggag atcaaaagtt
    16741 aatctgtttg tatttgtagc tggataaacc gtataaggtt gatataaatt cataccgaat
    16801 tgattaattt ttttcatttg tgcaaaatga tgtggtggtg caggttggtc agaaatgagt
    16861 ttatcgataa aggtagcttc gttattttca gaaaaagccc agttcgtttg tttttcatag
    16921 ccaagagtag atgttggaat agcacctaaa gatttaccac aaggactacc agcgccatgg
    16981 ccaggccaaa tttgaatgta atctggcaag tctttaatac tttcaatcga tttaaacatt
    17041 tgtttagcgc ctatttcaga tgatccttct actttaaccg ctttttctag taaatcaggt
    17101 ctaccgatat ctcctacaaa aataaaatca ccactgaata gtcccattgg aacttgtgct
    17161 ccagcacctt cgtcagtaag taaaaaactt atactttctg gcgtgtgacc cggtgtatga
    17221 agcactttta attttatatt tcctacataa atatcgtcat tatgttgaac aaaatgagtg
    17281 tggttaggca tatttttata acctaatgtg tcatcacttt cacccgatac ataaatatta
    17341 gcatttaact ttatagcaac atctctaatt cctgaagcaa aatctgcatg tatatgtgtt
    17401 tcagctgcat gagtaatggt taaaccttct tcatcagcaa ctcgaatata tgaagataag
    17461 tcacgaatag gatcaataat catggcttct ccagtttttt gacaaccgat taaataagat
    17521 gcttgagata aatgtttatc ataaaattgt ttaaaaaaca taatatcatt cctttctaat
    17581 tatataaata aattgtgatt agcttgttct gtatatccaa tatatgcacc tacgccaccg
    17641 tattctacat catcacgtag ttcttctttt gtaatgccca tcacatccat actcattgta
    17701 caagcgataa gtttaacacc ttgctcaact gcttgatcaa taagagaagg taaagtatcg
    17761 acatttttct ttttcatgac ataacgcatc attagattgc ctaaaccaaa catattcatt
    17821 ttagaaatag gcatgttaat tggtgaattt ggaagcatga agtcaaaaag ttttgcaata
    17881 ccttttttct taatacgttg actttgaatt tttttaagtg catttaagcc ccaaaatgtg
    17941 caaaaaatgg ttacatctct acctgcagct ttagcaccat tagcaataat cattgctgca
    18001 actgctttat ctagctcgcc gctaaataaa acaattgttg ttccactttt cgtgtgtgtc
    18061 acttctatat ttttattttc ttctttttga ataatagcgc gaatttcatt gccaaaatcg
    18121 ttgagtctaa caagcgtatg tccagtttgt ttgacccaac ttttaatatc atttaaaaat
    18181 ccgtgatcag tcacaacaac ttctatttga tcgccaatag cgatgttttt gatttcttta
    18241 ctaatattaa caataggtcc tggacactgt agattactat aattgaatgt cttacgatta
    18301 tctttaattt ctctatcttc ttttacttta gataaattat cattatgatg ttgttgttcg
    18361 tatgcggtat aacctccgtc taaattcact acatcgtatc cgcgttgtgc aagaaattga
    18421 ctggcttttc tacttctatt accactttta caatagatat agtaagtttt atttttgctt
    18481 tgtttaaaag tctctatatt ttcaactgaa tgtaataaag cgtttttaat gtgtcctaat
    18541 tcaaattctt caggatgtcg aacgtcaatt aattgaccct tagaactcaa ttcttgtaat
    18601 tcttttttag tgaaatcatt aatgtgtttc gttttatatt gtgacataat tgcctccttt
    18661 taaataccta tgggggtata ttataacgaa ttagatagtt tgtcaaatac ctatgggggt
    18721 atttgacaaa ctaaaattta atcaatatga tgtaattatt aaaaatgaat gtggagtgaa
    18781 atatattgga atataataaa aagatgatta atcgtattca tcgcatacaa ggacagctta
    18841 atggagtcat taaaatgatg gaggaagaaa aaaattgtaa agacgtcatt agtcaattaa
    18901 gtgcatctaa aagttctatt caacgtttaa tgggtattat tattagcgag aacttagtag
    18961 aatgcgtcaa aatgtctgaa gaaaatagtg aagattctca ggcactaatt aatgaagctg
    19021 ttgaattatt aataaaaagt aaatgataag tataacagta attatagtaa tgttagttat
    19081 tggtatatta ggaggattta tttctggatt agtcggtata gggggagcca ttgttattta
    19141 ccctgctctc ttattattac caccattatt tggtttacct acttatagtg cttatattgc
    19201 ctcaggatta acttcaagtc aggtgttttt tagtacattg agtggatctt taaaagcata
    19261 taaaaataaa aatttttcta gaacgcttat acttaatatg ggaagtggaa tggtaatagg
    19321 tagtattcta ggtgcgttat tagcaactgt atttaatagt cagtttgtta atgtaattta
    19381 tataattatt gctttgttag ctcttattct aatgtttatt aaagtcacac catctactag
    19441 tcatattaag tttaatcgcg tacttttaat tacaataggt ggtatcatcg gtttagtatc
    19501 tggtattgta ggagctggtg gagcattcat tattattcca gtactacttg ttatatttaa
    19561 attaccaatg aatatggttg ttacaaatag tattgtaatt gcattcattt cttctattgg
    19621 agcatttatt attaaattat tacagggtta tattcctatc aatagtgcaa taccgttaat
    19681 tttaggtagt atactattta cgcctctagg catgaaaata gggcaaaaaa tacctgattc
    19741 tattcaaaaa gggattgtaa gtattttaat cgtcattgca atcattaagt tgatatttta
    19801 aaaatatggg agtggggcaa catttatttt gaatttgtag tctcgctccc taaatcaatt
    19861 tatacggtat ttaattcaaa ggttatttat tagaatctaa tcaattttac aaaattttaa
    19921 caaaaaaaac tttttctaaa ttgatatata atagcgggta tggtaatttt aaaatagata
    19981 ctcgtatcta actaattttt aggggtggtt aattgtatga ataaaaattc gaagaagaag
    20041 ctcgattttc ttccaaacaa gcttaataag tactcaatta gacgtttcac tgtagggaca
    20101 gcttcgattt tagtaggagc tactttaatt ttcggtgttg caaatgatca agcagaagcc
    20161 gctgagaata acacaactca aaagcaagat gatagttcag atgcaagtaa agtaaaaggt
    20221 aatgttcaaa ctattgaaca atcttctgca aattcaaatg aatctgatat tcctgaacaa
    20281 gttgatgtaa ctaaagatac aactgaacaa gcatcaacag aagaaaaagc aaatacaact
    20341 gaacaagcat caacagaaga aaaagcagat acaactgaac aagcaacaac agaagaagcg
    20401 ccaaaagctg aaggaacaga caaagtagaa acagaagaag cgccaaaagc tgaagaaaca
    20461 gacaaagcaa cagaagaagc accaaaaact gaagaaacag acaaagcaac aacagaagaa
    20521 gcgccaaaag ctgaagaaac agacaaagca acagaagaag caccaaaaac tgaagaaaca
    20581 gacaaagcaa caacagaaga agcgccagca gctgaagaaa caagcaaagc agcaacagaa
    20641 gaagcgccaa aagctgaaga aacaagcaaa gcagcaacag aagaagcgcc aaaagctgaa
    20701 gaaacagaaa aaacagcaac agaagaagca ccaaaaactg aagaaacaga caaagtagaa
    20761 acagaagaag cgccaaaagc tgaagaaaca agcaaagcag caacagaaaa agcaccaaaa
    20821 gctgaagaaa caaacaaagt agaaacagaa gaagcgccag cagctgaaga aacaaacaaa
    20881 gcagcaacag aagaaacacc agcagttgaa gacacaaatg ctaagagcaa ttcaaatgct
    20941 caaccatcag aaactgagag aactcaagtt gtagatacag ttgctaaaga tttatataaa
    21001 aaatctgaag ttacagaagc agaaaaagct gaaattgaaa aagtattacc aaaagatatt
    21061 tcaaacttat ctaatgaaga aattaaaaaa atagctttaa gtgaagtact taaagaaaca
    21121 gctaacaaag aaaacgcaca accaagagca acattccgtt cagtaagcag caatgctaga
    21181 acaacaaatg ttaactattc agcaacagca ttaagagcag ctgcacaaga cacagttact
    21241 aaaaaaggaa ctggtaactt tactgcgcat ggagatataa tccataaaac ttataaagaa
    21301 gaattcccta atgaaggcac gctaactgca ttcaatacaa acttcaatcc taatacagga
    21361 actaaaggcg cattagaata taatgataaa atagatttta ataaagactt tacaattact
    21421 gttccagtag caaacaacaa ccaaggtaat acaacaggag cagatggctg gggcttcatg
    21481 tttactcaag ggaatggcca agacttctta aaccaaggtg gtattttaag agacaaaggt
    21541 atggcaaatg catctggttt taaaattgat acggcatata ataatgttaa tggtaaagtc
    21601 gataaactcg atgcagataa aacaaacaat ctaagtcaaa ttggcgcagc aaaagttggt
    21661 tacggtacat ttgttaaaaa tggtgcagat ggtgtgacta accaagttgg tcaaaatgcc
    21721 ctaaatacaa aagataaacc tgtaaataaa ataatttatg cagataatac aactaatcat
    21781 cttgatggtc aattccatgg ccaaagatta aatgatgtag tattaaatta tgatgcagca
    21841 acaagtacaa taactgctac atatgcagga aaaacatgga aagctactac agatgattta
    21901 ggaattgata aatcacaaaa atataatttc ttaattactt caagtcatat gcaaaataga
    21961 tattctaatg gaattatgag aacaaatctt gaaggtgtaa caattacaac gcctcaagct
    22021 gatttaattg atgatgtgga agtaacgaaa caaccaattc ctcataaaac tattcgtgag
    22081 tttgatccaa ctctagaacc aggctcacct gatgttattg tacaaaaagg tgaagatgga
    22141 gagaaaacaa caactacacc aactaaagtt gaccctgata caggagatgt agttgaacgt
    22201 ggtgaaccaa caacagaagt tacaaaaaat ccagttgacg agattgtaca ctttgcacct
    22261 gaagaagtac cacaaggtca taaagatgag ttcgatccaa acttaccaat tgacggtaca
    22321 gaagaagtac caggtaaacc aggcatcaag aatcctgaaa caggtgaagt agtaacacct
    22381 ccggt
//
LOCUS       DAPDIM010000045        22290 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000045 DAPDIM010000000
VERSION     DAPDIM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 22290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22290
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.045"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            144..437
                     /locus_tag="RFE25_001866"
                     /pseudo
     CDS             144..437
                     /locus_tag="RFE25_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(573..1475)
                     /gene="cvfB"
                     /locus_tag="RFE25_001867"
     CDS             complement(573..1475)
                     /gene="cvfB"
                     /locus_tag="RFE25_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HDU2816917.1"
                     /translation="MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDD
                     DELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREV
                     LVPWEDLPKVKSLWPQPGDHLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNE
                     VIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSF
                     LPLAHERLDDDGQVIFDLLVEYDGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQ
                     KIINIETGKITLTKKGWSRIDSKE"
     gene            1622..3223
                     /locus_tag="RFE25_001868"
     CDS             1622..3223
                     /locus_tag="RFE25_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDU2816918.1"
                     /translation="MLQVTDVSLRFGDRKLFEDVNIKFTEGNCYGLIGANGAGKSTFL
                     KILSGELDSQTGHVSLGKNERLAVLKQDHYAYEDERVLDVVIKGHERLYEVMKEKDEI
                     YMKPDFSDEDGIRAAELEGEFAEMNGWNAEADAANLLSGLGIDPTLHDKKMAELENNQ
                     KIKVLLAQSLFGEPDVLLLDEPTNGLDIPAISWLEDFLINFDNTVIVVSHDRHFLNNV
                     CTHIADLDFGKIKVYVGNYDFWYQSSQLAQKMAQEQNKKKEEKMKELQDFIARFSANA
                     SKSKQATSRKKQLEKIELDDIQPSSRRYPFVKFTPEREIGNDLLIVQNLSKTIDGEKV
                     LDNVSFTMNPNDKAILIGDSEIAKTTLLKILAGEMEPDEGSFKWGVTTSLSYFPKDNS
                     EFFEGVNMNLVDWLRQYAPEDEQTETFLRGFLGRMLFSGEEVKKKASVLSGGEKVRCM
                     LSKMMLSSANVLLLDEPTNHLDLESITAVNDGLKSFKGSIIFTSYDFEFINTIANRVI
                     DLNKQGGVSKEIPYEEYLQEIGVLK"
     gene            4285..5490
                     /locus_tag="RFE25_001869"
     CDS             4285..5490
                     /locus_tag="RFE25_001869"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDU2816919.1"
                     /translation="MVTRSVLKFGGSSVSDFTKIKRIAEMLKERVNQDEQLIVVVSAM
                     GNTTDQLMTNVSTLTKAPKQQELALLLTTGEQQTVSYLSMVLNDIGVNAKAMTGYQAG
                     IKTIGHHLKSKIAQINPQTFEQAFQENDILVVAGFQGINEHQELTTLGRGGSDTTAVA
                     LAVSNQIPCEIYTDVDGVYATDPRLLPKAKRLDIVSYEEMMEMSALGAGVLETRSVEL
                     AKNYNIPLYLGKTLSNVKGTWIMSNEEILEKKAVTGVALDKHMMHVTISYPLPDNQLL
                     TQLFTELEEGAVNVDMISQIVNLDGLQLSFTIKDSDFHQISMILETLKNQYEALAYKI
                     NEHYVKISLIGSGMRDMSGVASKAFLTLIENNIPFYQTTTSEISISYVIDDFNGQQAV
                     EKLYDAFNI"
     gene            5554..6543
                     /locus_tag="RFE25_001870"
     CDS             5554..6543
                     /locus_tag="RFE25_001870"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDU2816920.1"
                     /translation="MTKLAVVGATGLVGTKMLETLNRKNIPFDELVLFSSARSAGQEV
                     EFQEKTYTVQELTDARASEHFDYVLMSAGGGTSEHFAPLFEKAGAIVIDNSSQWRMAE
                     DIDLIVPEVNEPTFTRGIIANPNCSTIQSVVPLKVLQDAYGLKRVAYTTYQAVSGSGM
                     KGKKDLAEGVNGKAPEAYPHPIYNNVLPHIDVFLENGYTKEEQKMIDETRKILNAPDL
                     KVTATCARVPVQDSHSVEIDVTLDKETTAEDIKALFDQDDRVVLVDNPENNEYPMAIN
                     STNKDEVFVGRIRRDDSLENTFHVWCTSDNLLKGAALNAVQVLEQVMRLKGAN"
     gene            6545..7432
                     /locus_tag="RFE25_001871"
     CDS             6545..7432
                     /locus_tag="RFE25_001871"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDU2816921.1"
                     /translation="MTHLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVN
                     GTTAESPTLTTDEKERILKTVIDLVDKRVPVIAGTGTNDTEKSIQASFQAKALGADAI
                     MLITPYYNKTNQRGLVKHFEAITDAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIV
                     ALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQ
                     ALYDAQQSGLDIQDQFKPIGTLLSALSVDINPIPIKALTSYLEFGNYELRLPLVSLED
                     TDTKVLREAYDTFKAGENE"
     gene            7429..8151
                     /locus_tag="RFE25_001872"
     CDS             7429..8151
                     /locus_tag="RFE25_001872"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDU2816922.1"
                     /translation="MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQ
                     HIADVKDADVAIDFSNPNLLFPLLDEEFHLPLVVATTGEKEKLLNKLDELSQNMPVFF
                     SANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKEN
                     VTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFAN
                     GAIQAAERLVNKPNGFYTFDNL"
     gene            8178..8897
                     /gene="dapD"
                     /locus_tag="RFE25_001873"
     CDS             8178..8897
                     /gene="dapD"
                     /locus_tag="RFE25_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDU2816923.1"
                     /translation="MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFG
                     SEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIR
                     EQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIE
                     PPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIK
                     QASEVQDTKKEIVAALRKLND"
     gene            9040..10191
                     /locus_tag="RFE25_001874"
     CDS             9040..10191
                     /locus_tag="RFE25_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDU2816924.1"
                     /translation="MNELEFVTKHRRHLHQHPELSLHEFETTAYIKAFLDSLNIKYDC
                     PLETGVIAYLEGNGSHTIAYRADIDALPILEENDVPYRSQSDHVMHACGHDGHTTALM
                     LFVQRCKDMQDAGQLPQNVVFIFQPAEETGGGANRLIKAGAFDKYPIEAVFGIHVNPF
                     ADEGIAVIRDEEITASATEYRFFLTGLSSHVADKEQAHSCGEALQHVLTQISQIQQFH
                     LNGLKRNIVHIGHFKAGEAINTVPSNGYLEGTIRTYDIDDLTIVKNQMHKIAESVKLL
                     FNVECEVKFAEGYPPTINSPKLRTQIEDALIKADLNVYDKPTPFLFGEDFSFYGQQLA
                     PAYFVFIGTRNEDKGFVTGLHTSHLNFDEKALINVVNFYENLLNNYKEV"
     gene            10196..11281
                     /locus_tag="RFE25_001875"
     CDS             10196..11281
                     /locus_tag="RFE25_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDU2816925.1"
                     /translation="MTATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQ
                     FIHAGIDTFSTTSLREAIQIRQLAPDATIFLMNAVYEFDLVREHQIHMTLPSLTYYYN
                     HKNDLAGIHVHLEFENLLHRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADE
                     FDVSDYNVERSQWMEIVEALLSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIAL
                     YGSRPYSSLNQHDIVQSLTVKAHVIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGY
                     GDGILRTRAKHEALINGKRYPIRALMMSHMFVEVDGNVHAQDEVILYNNDIRIDEYTF
                     KGVGANSEQLSAMNHDSLKKEYISNDC"
     gene            11271..12536
                     /gene="lysA"
                     /locus_tag="RFE25_001876"
     CDS             11271..12536
                     /gene="lysA"
                     /locus_tag="RFE25_001876"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDU2816926.1"
                     /translation="MTVKYNQNGELTMDGISLKTIAQSFGTPTIVYDELQIREQMRRY
                     HRAFKDSGLKYNISYASKAFTCIQMVKLVAEEDLQLDVVSEGELYTALEAGFEPSRIH
                     FHGNNKTKHEIRYALENNIGYFVIDSLEEIELIDRYANDTVQVVLRVNPGVEAHTHEF
                     IQTGQEDSKFGLSIQYGLAKKAIDKVQQSKHLKLKGVHCHIGSQIEGTEAFIETAKIV
                     LRWLKEQGIQVELLNLGGGFGIKYVEGDESFPIESGIKDITDAIKSEIKVLGIDAPEI
                     GIEPGRSIVGEAGVTLYEVGTIKEIPEINKYVSIDGGMSDHIRTALYDAKYQALLVNR
                     NEEADDSVTIAGKLCESGDIIIKDAKLPSSVKRGDYLAILSTGAYHYSMASNYNQMQK
                     PSVFFLKDGKAREVIKRQSLRQLIINDTK"
     gene            complement(12776..13177)
                     /gene="msa"
                     /locus_tag="RFE25_001877"
     CDS             complement(12776..13177)
                     /gene="msa"
                     /locus_tag="RFE25_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sarA expression modulator protein Msa"
                     /protein_id="HDU2816927.1"
                     /translation="MKYLILSLVANLLVFGVLSAIGLNINILAAMMIVLVIPIMISGI
                     LFFKTNIDKTYIFFNIIFIDFYYYIYNVHLMTLPKFNNYIKAEMMELEDIDVLITSKD
                     FGFDEILFYTLYLLLILIVLYYLKKQVKHKI"
     gene            complement(13374..13574)
                     /gene="cspA"
                     /locus_tag="RFE25_001878"
     CDS             complement(13374..13574)
                     /gene="cspA"
                     /locus_tag="RFE25_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspA"
                     /protein_id="HDU2816928.1"
                     /translation="MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQDGYKSLEEG
                     QAVEFEVVEGDRGPQAANVVKL"
     gene            complement(13745..14053)
                     /locus_tag="RFE25_001879"
     CDS             complement(13745..14053)
                     /locus_tag="RFE25_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HDU2816929.1"
                     /translation="MWTVTKIRADYEGWWLFSDWPENIVEKYQYQDFDDMFKHYQQLI
                     NQCKVQFDNYVTGKYNIYAFYNNCDMNYCEDCEEDLQIFYSFIVLQNNEVYYKLPIID
                     "
     gene            14216..14485
                     /locus_tag="RFE25_001880"
     CDS             14216..14485
                     /locus_tag="RFE25_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDU2816930.1"
                     /translation="MRHIHLQVFGRVQGVGFRYFTQRIAMNYNIVGTVQNVDDYVEIY
                     AQGDDADIERFIQGVIEGASPASNVTSHQLEELELNQKLSDFRSI"
     gene            14504..15133
                     /locus_tag="RFE25_001881"
     CDS             14504..15133
                     /locus_tag="RFE25_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDU2816931.1"
                     /translation="MTVRYNISHIFGVLVGIPVAFLTSIFGMIALDVSFLIDMSIGIV
                     GFLMTYLPIQKLTSRKYLNEIGLTRKDYRYIRNQLNHTHQKLRGILKTYVNIRSIKDF
                     RQINDIYQISRSIYTTVRQRPASFYKVEGFFYSHIDNALNLVDAYTRLAKMPKKSINE
                     QQKLEQTRITLDEVKRTLIADLKRLNEDDYERLDIEMELNKLHQKHHQD"
     gene            15165..16301
                     /locus_tag="RFE25_001882"
     CDS             15165..16301
                     /locus_tag="RFE25_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDU2816932.1"
                     /translation="MTENKSFKESHPLDDFISDKELSNTTIQKEKLTIEQQKQVDTIS
                     KQINPLDNEGLLAFGSDLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLMSKLKSVNPN
                     ELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDT
                     LYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQQVADMQQFID
                     RLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTL
                     MRQRNAVAAQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIE
                     TIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGPNKQS"
     gene            complement(16374..17717)
                     /gene="brnQ"
                     /locus_tag="RFE25_001883"
     CDS             complement(16374..17717)
                     /gene="brnQ"
                     /locus_tag="RFE25_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDU2816933.1"
                     /translation="MNKNTWVIGFTLFAMFFGAGNLIFPPNLGLDSGQFFWPAILAFV
                     LTGIGLPLLGVIVGALDKEGYIGALNKISPKFSILFLIIIYLTIGPLFAIPRTASTSF
                     EMTITPIIHSNSSIALFIFTIIYFIVVLYICLNPSKLIDRIGSLLTPLLLITILAMII
                     KGYLDFSGNSAGKGNEALYHSNFSSFAEGFTQGYLTMDAIAAIAFSMIVVNAVKLTGI
                     TKTNQIFKQTLTAGLIAAVALIFIYISLGYIGNHMPVSDMTLDQLKSKDRNIGTYLLT
                     TMASTGFGSFGKYLLGIIVALACLTTACGLIVAVSEYFHRIVPKVSYKAFVLVFILMS
                     FIIANQGLNAVISMSIPVLSIVYPVAITVVLLILIAKFIPTKRISQQIPVIIVFILSI
                     FSVISKLGWLKINFIESLPLRAYSLEWFPVAIIATILGYLVGIFVKQDPIKYQQE"
     gene            complement(17942..19828)
                     /locus_tag="RFE25_001884"
     CDS             complement(17942..19828)
                     /locus_tag="RFE25_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation protein NorD"
                     /protein_id="HDU2816934.1"
                     /translation="MSDRFIKFNDEQLDAKQVMMLQDLARLLLKNEQTQVKIQKFPYY
                     NPVQNVLITSWFWSHRPSHIEMAGLKTDVMLAAYGYHMMDVQIVNEVVQDKTFKHPKF
                     YQQLFKLLEDMRVLNSIKVERPSTAKLIDLRLDTRVSYTESQIKVYRTKTQYTDLLFL
                     YLEHAFLSQDFFDIPSIHSDLDDILVNMFLYLPNFFQNQNSEDNMYLAQRIMYQVDDI
                     LKEDMLNEYYYLPKTLYNTLASPEFDDLKRTDASQVDGQDDTSEDDDNESEKADSKSA
                     DSESKGGAYLEMELHEGQNSETLGNDEAREGDATDDMTDMMTKKGKGSNDTLNREEGD
                     AVGQSQAFQLDGVNKNVEIKWQIPEIEPQYVLEYQESKQDVQYEIKDLIQIIKKTIER
                     EQRDARFNLTKGRLQKDLINWFIDDQYKLFYKKQDLSKSFDATFTLLIDASASMHDKM
                     AETKKGVVLFHETLKALNIKHEILSFSEDAFDSDDHAQPNIINEIINYDYSTFEKDGP
                     RIMALEPQDDNRDGVAIRVASERLMRRNQHQRFLIVFSDGEPSAFNYSQDGIIDTYEA
                     VEMSRKFGIEVFNVFLSQDPITEDVEQTIHNIYGQYAIFVEGVAHLPGHLSPLLKKLL
                     LKSL"
     gene            complement(19842..20633)
                     /locus_tag="RFE25_001885"
     CDS             complement(19842..20633)
                     /locus_tag="RFE25_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDU2816935.1"
                     /translation="MALKHYKNSDSTVFNDAKALFDLNKNILLKGPTGSGKTKLAETL
                     SEVVDTPMHQVNCSVDLDTESLLGFKTIKTNAEGQQEIVFVDGPVIKAMKEGHILYID
                     EINMAKPETLPVLNGVLDYRRQITNPYTGEVIKAVPGFNVIAAINEGYVGTLPMNEAL
                     KNRFVVIHVDYIDGDILKNVIKEQSLLQDDKQIEQIIKFNEDLRTMSKQGQISEEAAS
                     IRALLDLCDLITVMPVERAIKRTIIDKLEDEREQQAIYNAVELNF"
     gene            complement(20814..21017)
                     /locus_tag="RFE25_001886"
     CDS             complement(20814..21017)
                     /locus_tag="RFE25_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499941.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816936.1"
                     /translation="MLHETWKERTPIKKVEVINTDAKKFTVSDMLTVGKQYDVINETE
                     EYYQIIDNSGLVGGYYKTYFKEV"
     gene            complement(21046..21855)
                     /locus_tag="RFE25_001887"
     CDS             complement(21046..21855)
                     /locus_tag="RFE25_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDU2816937.1"
                     /translation="MCGLRSITLGTTNIEQTKHFMVDILGLNYEELLENSIRFGDADI
                     SPGTRLQFIQVPSEQLEESHFVGIGLRTPTDSGLEEYAEILSNKDIPFTTVKELNGNK
                     YFSLEDNNGHIFSIYSNENNYGVGLGMPSFESAVNPLHQVQGLGPVILKVNHVDITGQ
                     ILTNIFGLEVFAEYQPFDNADYHVQVFKVGTGGLGGEIHLMPVETEMTMPEYGAVDQV
                     EFETKDADFFNQAKSRLDEVEIPYQTLEQDDIESIRITENSGLSFIFTLQK"
BASE COUNT         7745 a         3618 c         3681 g         7246 t
ORIGIN      
        1 tgccgtctca gccaccccaa ccggcacatt gttgtaagct gactatatgt cagcttctgt
       61 gttggggccc ctgtcttcga ctggcactgc tccctcagga gtctcgccat taatactacg
      121 tattaacatg taattttact ttgaaataca ttaaagccca aattaatcaa aagctttctg
      181 aaccagaaac gaaaaaaatc tatagtcata gaaaaattta tgtagagcct gtttttggat
      241 ttatgaaggt tattttgggt ttcactcgaa tgtcagttcg aggaataaat aaagttaaac
      301 gagagctagg ttttgtatta atggcactta atataaggaa aatagcagct caacgagctg
      361 tacattataa aatacatatc aaaaaagcta atttccatca aataattaat agaaatcagc
      421 ttttttacat tgcctaagaa cttaatgtcc cagcctattc gtttgaatta tttaattttt
      481 tactttgaaa ggaatgttta aaaaactact tcatctgtcc gacttaatat tgaatataaa
      541 aaacacgcat cctacgacac gtgtaaaaat gattattctt ttgagtcaat tcgactccaa
      601 ccttttttag ttaaagtgat tttacctgtt tctatattaa taatcttctg tttatataag
      661 tgaccgattg cacgtttgaa tgaaccttta ctcatattga atacttcttt aatcgcttca
      721 gggcttgatt tgtcccagaa tggtaattca ccatcatatt caactagtaa atcaaagatg
      781 acttggccgt catcgtctaa acgttcatgt gcaagtggta aaaatgaacc atttaactca
      841 cctttatcat tatgcccgat aattctaact tgaacagatt cacctaatct tggttcagct
      901 ttacgttctg attcatgtac gaaaattttg taacctgatt cgcttaataa gaagctacca
      961 attcgtaata cgcggtaagg tttggcttca atgacttcgt tttttaaatt atcatcgtgt
     1021 acaggtgtaa acatattttc tacaacagat tcactcgcta aacgtccata catatgattc
     1081 tcacggtcaa ttcgtaatgt aactagcaaa tgatcaccag gttgtggcca tagtgatttc
     1141 acttttggta aatcttccca tggtactaac acttcacggg gtaaaccaac atctatacgt
     1201 gccccatcgc gatccgtttt aagtacttta gcaaaatcat atttatcttt cgtaatatca
     1261 ggcatatttt gagttgcaaa taattcacct gaacggtttg gataaatgaa gaaactatat
     1321 tcttcaccta cttctaattc atcatcatcg ttcatttctg attggtttaa ctttacgttt
     1381 tcaccgtttg gtccttttaa aaggtaagtt gagccttgta accctactac ttcaaggaat
     1441 tctatagaac ctactatatc tttgtctaat gccatgttat tctccttcga ttcttgtatt
     1501 ctttattatt ataacatgtg tgagtcattc tatcattaca acttatatga ggtcgaaact
     1561 gtgacgataa tatgatataa ttcttccgtt agaatatcga atgaaaaaaa ggagaaaatg
     1621 catgttacaa gtaactgatg tgagtttacg ttttggagat cgtaaactat ttgaagatgt
     1681 aaatattaaa tttacagaag gtaattgtta tggattaatt ggtgcgaatg gtgcaggtaa
     1741 atcaacattc ttaaaaatat tatctggtga attagattct caaacaggac atgtttcatt
     1801 aggtaaaaat gaacgtctag ctgttttaaa acaggaccac tatgcttatg aagatgaacg
     1861 cgtgcttgat gttgtaatta aaggtcacga acgtctttat gaggttatga aagaaaaaga
     1921 tgaaatctat atgaagccag atttcagtga tgaagatggt atccgtgctg ctgaacttga
     1981 aggtgaattt gcagaaatga atggttggaa tgctgaagct gatgctgcta accttttatc
     2041 tggtttaggt atcgatccaa ctttacacga taaaaaaatg gctgaattag aaaacaacca
     2101 aaaaattaaa gtattattag cgcaaagttt attcggtgaa ccagacgtac tattactgga
     2161 tgagcctact aacggtctcg atattccagc aatcagttgg ttagaagatt tcttaattaa
     2221 ctttgataat actgttatcg tagtatcgca tgaccgtcat ttcttaaata atgtatgtac
     2281 tcatatcgct gatttagact tcggtaaaat taaagtttat gttggtaact atgatttttg
     2341 gtatcaatct agtcagttag ctcaaaagat ggctcaagaa caaaacaaga aaaaagaaga
     2401 aaaaatgaaa gagttacagg actttattgc acgtttctca gctaacgctt ctaaatctaa
     2461 acaagcaaca agtcgtaaaa aacaacttga gaaaattgaa ttagatgata ttcaaccatc
     2521 atcaagaaga tatcctttcg ttaaattcac gcctgagcgt gagattggta acgacttatt
     2581 aatcgttcaa aatctttcta aaacaattga cggcgaaaaa gtattagata atgtatcatt
     2641 cacaatgaat ccaaatgata aagcgatttt aattggagat agtgaaattg caaaaacaac
     2701 attacttaaa atattagctg gcgaaatgga accagacgaa ggttcattta aatggggtgt
     2761 tactacatca ttaagttact tccctaaaga taactcagag ttctttgagg gtgtaaatat
     2821 gaatctcgtt gattggttaa gacaatatgc tcctgaagat gaacaaacag aaacattttt
     2881 acgtggtttc ttaggtcgta tgttatttag tggtgaagaa gttaagaaaa aagctagtgt
     2941 gctttcaggt ggagaaaaag tacgttgtat gctaagtaaa atgatgttat caagtgcgaa
     3001 tgtactttta cttgacgaac ctactaacca cttagactta gaaagtatta ctgctgtcaa
     3061 tgatggtctt aaatcattta aaggttctat catctttact tcttatgact tcgaatttat
     3121 caacacgatt gcaaaccgtg ttatcgattt aaataaacaa ggcggcgttt caaaagaaat
     3181 tccatatgaa gaatacttgc aagaaatcgg cgttttaaaa taaacataat atgtagaatt
     3241 tcttttcgaa aatctctgta ttgaggcccg accaacttgc acattattgt aagttggctt
     3301 actgtcacct tctatattgg gacttattcc gcaacttgta ttgtttgtag aaattaggaa
     3361 tccaatttct ctatgtgttg caccgacaag gattgaaaaa agctagctac aaagtcattt
     3421 tcattcagtc aactactgtc aatataacat tgcagggtct agggcattga ttcatgcccg
     3481 agactatatt caatttaata gacattaact ggtcgtgagg ctgggacata aatccctaaa
     3541 aaaacagcag taagataatt ttcaattaga aaatatctta ctgctgttct ctatttatac
     3601 aatacttcgt attgaatggc ttcgctttgc ccgtctggca cattactgta aaattctata
     3661 aatagaattt ttgatgacgg gtcccttcct agggtgccgt ctcagcctct ttttacattg
     3721 cctaagaact taatatccca gcctcgtgtc ctttttattt tattttttag cacatcagca
     3781 cagtgaacac cccttctcta aattacaaat acagttatca ccgcattaaa agagtacatt
     3841 tatttaatgt gcatattgag tatgctataa gtattttgaa ttttattttt caaaaagtct
     3901 cattatcacc accttttaaa atataagcaa cgctataact tgaattttca ggttattcca
     3961 aaaaatctaa attatcggtt tacattcata tttgtcatat gtataatgaa cacataccaa
     4021 tttaataata ttttgatgag gcgcatcaat catgagtaaa gtttagatta ctgtctgcta
     4081 acagctgaat ttgaaagggt gcgatgccga agcgattata atagcagtta taatttgttg
     4141 gactttttgg ttaagagctg agagtttgtc attatttaaa aataatggag tgcatcactt
     4201 gtatatagat taagagcaag ttcgcattcc gaacttgttc tttttttatt attgtgtgcc
     4261 cttcctaaca attaggagga ttatatggta acaagaagtg tgttgaaatt tggcggatca
     4321 tccgtcagtg attttacaaa aataaaaagg atcgctgaaa tgttaaagga gcgagtcaat
     4381 caagatgaac aattaattgt cgttgtaagt gctatgggta acacaacaga tcaattaatg
     4441 acgaatgtat cgaccttgac taaagcacca aaacaacaag aactggcatt attattgaca
     4501 accggagagc aacaaactgt atcttattta tcaatggtat taaatgatat cggtgtgaat
     4561 gccaaagcaa tgactggcta tcaagcgggt attaaaacca ttggccatca tttaaaaagt
     4621 aaaattgctc aaattaatcc tcaaacattt gaacaagcct ttcaagaaaa cgatatttta
     4681 gtagttgctg gatttcaagg catcaatgaa catcaggaat taacaacttt aggcagaggc
     4741 ggttctgata cgaccgctgt ggcacttgct gttagtaatc aaataccttg tgaaatttat
     4801 accgacgttg atggtgtgta tgccactgac ccaagacttt taccaaaggc taaacgacta
     4861 gacatcgtct catatgaaga aatgatggaa atgagcgctt taggtgctgg tgtacttgaa
     4921 acaagaagtg ttgaattagc taaaaactat aatatccctt tatatttagg aaaaacttta
     4981 tcgaacgtga aaggaacatg gattatgtca aatgaagaaa tattagagaa aaaagcagtt
     5041 actggtgtgg ctttggataa acatatgatg catgtaacaa ttagttatcc cctacctgac
     5101 aatcagctac ttacccaact atttacggaa cttgaagaag gtgctgtaaa tgttgatatg
     5161 atttcacaaa tcgtcaactt ggatgggcta caactatcct tcacgattaa agatagtgat
     5221 tttcatcaaa tttctatgat tcttgaaaca ttaaagaatc aatatgaagc attagcttat
     5281 aaaatcaatg agcattatgt caaaatttca ttaattggct caggcatgcg tgatatgtca
     5341 ggtgtggcat caaaagcatt tttgacatta attgaaaata atataccttt ctaccaaaca
     5401 acaacatctg aaataagtat ttcatacgtc attgatgatt ttaatgggca acaagcggta
     5461 gaaaaactat atgacgcatt taacatttaa tggtaaaatg attgttaaaa tattctaaaa
     5521 attggaaatt attataaaat ggagtgacaa gttatgacaa agttagcagt tgtgggtgca
     5581 acaggattag taggcacaaa aatgttggag acattaaatc gtaaaaatat tcctttcgat
     5641 gaattagtat tattttcatc agcacgttct gcagggcaag aagttgaatt tcaagaaaaa
     5701 acatatacag tacaagaatt aactgatgct cgtgctagtg aacatttcga ttatgtatta
     5761 atgagtgctg gtggcggtac aagcgaacac tttgccccac tctttgaaaa agctggtgca
     5821 atcgttatag acaattcaag tcaatggcgt atggcagaag atattgattt aatcgttccg
     5881 gaagtcaatg aacctacatt tacaagaggt atcattgcca atccaaactg ctctacgatt
     5941 caatctgttg tgccattaaa agtattgcaa gatgcttatg gtttaaaacg agtggcatat
     6001 acaacatatc aagctgtatc aggttcaggg atgaaaggta agaaagattt agctgaaggt
     6061 gtaaatggta aagcaccaga agcatatcca catccaattt ataataatgt gttaccgcat
     6121 attgatgtgt ttttagaaaa cggatataca aaagaagaac aaaaaatgat tgatgagacg
     6181 agaaaaattt taaatgcgcc agacttaaaa gtaacagcaa catgcgcacg tgtgcctgtt
     6241 caagatagtc atagtgttga aattgatgta acgcttgaca aagaaacgac agcagaagat
     6301 attaaagcgt tatttgatca agatgaccgc gttgttttag tagacaatcc agagaacaat
     6361 gaatatccaa tggcaatcaa ttccactaat aaagatgaag tgtttgttgg ccgtatacgt
     6421 agagatgatt cattagaaaa tactttccat gtatggtgta catcagacaa tttattaaaa
     6481 ggtgctgcat taaatgctgt acaagtattg gaacaagtta tgcgtttaaa aggagcgaat
     6541 taaaatgaca catttatttg agggtgttgg cgttgcactt acaacccctt ttacaaataa
     6601 caaagttaat cttgaagctt tgaaagcaca cgttaatttt ttactagaaa ataatgccca
     6661 agcaatcatc gttaatggaa ctactgctga gagccctact ttaacaacag atgaaaaaga
     6721 acgcattcta aaaacagtta ttgatcttgt agataaacgt gttcctgtca tagctggaac
     6781 tggaactaat gatactgaaa agtcaatcca agcttcattc caagctaaag ccttaggggc
     6841 tgatgcaatt atgttaatta cgccctacta caacaaaacg aaccaacgtg gtttagtcaa
     6901 acactttgaa gcgattacag atgctgtgaa attaccagtc gtgctgtaca atgttccttc
     6961 aagaacgaac atgacaattg aaccagaaac tgtagaaata ttaagtcaac atccttatat
     7021 agttgcttta aaagatgcta cgaatgattt tgagtattta gaagaagtga aaaagcgaat
     7081 tgatacaaat tcatttgcat tatatagtgg caatgatgac aacgtcgtcg aatactatca
     7141 acgtggcggt caaggggtta tctctgttat tgccaatgtc attcctaaag aatttcaagc
     7201 gttatacgat gctcaacaaa gtggattaga tattcaagat caatttaaac caatcggcac
     7261 actgttatca gccctatcag ttgatattaa cccaattcct attaaagctt taacaagtta
     7321 tttagaattt ggaaactatg aattacgttt accattggtt agcctagaag atacagatac
     7381 taaagtgctt cgtgaagcat atgacacatt taaagcgggt gaaaatgagt gaaaatatta
     7441 ctaattggct atggtgcaat gaatcaacgc gttgctagat tagcagaaga aaaaggacat
     7501 gaaatcgttg gggtcattga aaatacaccg aaagcaacaa cgccatatca acaatatcaa
     7561 catattgcag atgttaaaga tgccgatgtt gcaatagatt tttcaaatcc gaatctatta
     7621 ttcccattat tagatgaaga gtttcatttg ccattagttg tggcaacaac tggcgagaaa
     7681 gaaaaactac ttaataagtt agatgaattg agtcaaaata tgcctgtatt tttcagcgcg
     7741 aacatgagtt atggcgttca tgcactgact aaaattttag cagctgctgt tcccctactt
     7801 gatgatttcg acatcgaatt gactgaggca catcataata aaaaagtaga tgcaccaagt
     7861 ggtacgttag aaaaattgta tgatgtgatc gtatctttga aagaaaatgt aacacctgtg
     7921 tatgatagac atgaattaaa tgaaaaacgc cagccacaag atattggtat acattctatt
     7981 cgtggaggta cgattgtcgg tgaacatgaa gttctatttg ctggcactga tgaaacgatt
     8041 caaatcacac atcgtgcaca atcaaaagat atttttgcga atggtgctat acaagcagca
     8101 gaacgcttag ttaataaacc aaacggcttt tatacgtttg acaacttata aacatattaa
     8161 aggagatcga ttattttatg gtacaacatt taacagctga agaaattatt caatatataa
     8221 gtgatgctaa aaagtctaca ccaataaaag tatatttaaa tggtaatttt gaaggcatca
     8281 catacccaga aagttttaaa gtatttggtt cagaacaatc taaagtaatc ttttgtgaag
     8341 cggatgattg gaaacctttt tacgaagcat atggtagtca attcgaagat atagaaattg
     8401 aaatggatcg tcgcaattct gccattccat taaaagactt aacaaatacg aatgcacgta
     8461 ttgaaccagg tgcatttatt agagaacaag ccattattga agatggtgct gtcgttatga
     8521 tgggcgcaac aattaatatt ggcgcagtcg ttggcgaagg tacaatgatt gatatgaatg
     8581 ctactctcgg tggtcgtgct acaactggta aaaatgtaca tgtaggggct ggcgcagtat
     8641 tggcaggtgt gattgaaccc cctagtgcat caccagttat aatcgaggat gatgtattaa
     8701 tcggtgcaaa tgcagttatt ttagaaggtg tacgtgttgg taaaggtgct attgttgcag
     8761 ctggcgcgat tgtgacacaa gatgtaccag ctggtgcagt tgttgctggt acacctgcaa
     8821 aagtgattaa gcaagcttct gaagtacaag atactaaaaa agagattgta gcagcattaa
     8881 gaaaactgaa tgactagtga cgtcaacgta taataatttc aaggttgaga tacgattatg
     8941 tctcaacctt attgtttatc attgaataaa cttatgatca caaatttcga aatacgttac
     9001 actatttata tagtaattta acacaaagga ttgataatta tgaatgaatt agaatttgtt
     9061 acgaaacatc gccgtcattt acatcaacat cctgaattaa gcttacatga atttgaaaca
     9121 actgcttata ttaaagcgtt tttagatagt ttaaatatta aatacgattg cccattggaa
     9181 actggcgtca ttgcatactt agaaggtaat ggctcacata cgatagcgta tagagctgat
     9241 attgatgcgt tacctatttt agaggaaaat gatgtgcctt atcgcagtca atctgatcat
     9301 gtgatgcatg cttgtggaca tgatggtcat acaactgcat taatgctttt tgtacaacgt
     9361 tgcaaagaca tgcaagacgc aggtcaatta ccgcaaaatg tcgttttcat tttccaacct
     9421 gcagaagaaa ctggtggcgg tgcaaatcga ttaataaaag ccggtgcctt tgataagtat
     9481 ccaattgaag cggtatttgg tattcatgtt aacccatttg ctgatgaagg cattgcagtg
     9541 ataagagatg aagaaattac ggccagcgca acagagtatc gctttttctt aacaggcctg
     9601 tcaagtcatg ttgctgataa agaacaagct cattcttgtg gtgaagcatt acaacatgta
     9661 ttaactcaaa tatcacaaat tcaacaattt caccttaacg gtttgaaacg aaatattgtt
     9721 catattggtc attttaaagc tggtgaagcg attaacactg taccaagtaa tggttattta
     9781 gaaggtacaa ttcgtacata tgatattgat gatttaacaa tcgttaaaaa tcaaatgcac
     9841 aagatagcag aaagtgtcaa gcttctgttt aatgtagaat gtgaagttaa atttgcagaa
     9901 ggttatcccc ctacaatcaa tagtccgaaa ttacgtactc aaatagagga cgccttaata
     9961 aaagctgatt taaatgtcta tgacaaacca acgccattct tatttgggga agattttagt
    10021 ttttatggtc aacaactagc tccagcttac tttgttttta taggaacacg aaatgaagat
    10081 aaaggttttg taactggttt gcacacatca catttaaatt ttgatgaaaa agcgttaata
    10141 aacgtggtta atttttacga aaatttatta aataattaca aagaggtgta atacattgac
    10201 agcaacatgg tctgtaaata agaaaatatt tttacaaaat gcaatcacag tcaaaaacaa
    10261 tcagccatta atggcagttg ttaaaaataa tgcatatcac tatgacctag aatttgctgt
    10321 aactcagttt atccatgcag gtatagatac atttagcaca acatcactac gagaagcaat
    10381 tcaaattaga caacttgctc cagatgcaac aatcttttta atgaatgcag tttacgagtt
    10441 tgatttagtc cgtgaacatc aaatacacat gactttgccg tcgttgacat attactataa
    10501 ccataaaaat gatttagcag gtattcatgt tcacttagaa tttgaaaatt tattacatcg
    10561 gtctggattt aaagatttaa acgaaattaa agaagtattg aaagatcacc atcataatca
    10621 aaatgcaaaa atgattatta gtggtttatg gacccatttt ggatatgctg atgaattcga
    10681 tgtgtcagat tataatgttg aacgttcaca atggatggaa attgttgaag cacttttatc
    10741 tgaaggttat cagttcgacc taatccatgc tcaaaatagt gcgagttttt atcgggaagg
    10801 acaaatatta ctaccccacc atacacatgc gcgtgtaggt attgcgttat acggttcaag
    10861 accatatagt tcactgaatc aacatgatat agttcagtca ttaactgtaa aagcacatgt
    10921 tattcaagtg cgcgaagtac aagctggtga ttattgcggt tatagctttg cctttgaagt
    10981 gactaaaaac aatacaaaat tagctgtagt tgatatcggt tatggcgatg gaattttaag
    11041 aactcgtgct aaacatgaag cacttatcaa tggtaaacgc tacccgatac gtgcattaat
    11101 gatgagccat atgtttgttg aagtagatgg caatgtacat gcacaagatg aagttattct
    11161 ttataataat gatatccgca tcgatgaata tacctttaaa ggtgttggtg caaattctga
    11221 acaattaagt gctatgaatc atgattcttt aaaaaaggag tacatttcaa atgactgtta
    11281 aatataatca aaatggcgaa ttaacaatgg atggtattag tttaaaaacg attgcacaaa
    11341 gctttggtac acctaccatt gtttatgatg aactacaaat tagagaacag atgcgccgtt
    11401 accatcgcgc atttaaagat agtggattaa aatacaatat ttcatacgcc tcaaaggcat
    11461 ttacttgcat tcaaatggtc aaacttgtag ctgaggaaga tttacagtta gatgttgttt
    11521 ctgaaggtga attatataca gctttagaag caggttttga accgagtcgc atccatttcc
    11581 atggtaacaa taaaacgaaa catgaaatta ggtatgcttt agaaaataat atcggttatt
    11641 ttgttataga ttcattagaa gaaattgaat taatagaccg ctatgctaat gatacggttc
    11701 aagttgtatt acgagttaat ccaggtgttg aagcacatac acacgaattt attcaaactg
    11761 ggcaagaaga tagtaagttt ggattatcaa ttcaatatgg cttagctaaa aaagcaattg
    11821 acaaagtcca acaatctaaa cacttaaaat taaaaggtgt acattgtcat attggttcac
    11881 agattgaagg tacagaagca tttattgaaa ctgctaaaat tgttttacgt tggcttaaag
    11941 agcaaggtat tcaagttgaa ttattaaacc ttggtggtgg ctttggtatt aaatatgttg
    12001 aaggtgacga aagtttccct atcgaaagtg gtattaaaga tattacagac gcaataaaat
    12061 ccgaaattaa agttctaggt atagatgcac cagaaatagg tattgaaccg ggacgatcaa
    12121 ttgtaggtga agctggcgtt actttatatg aagttggaac cattaaagaa attccagaga
    12181 ttaataaata tgtttcaatc gatggcggta tgagtgatca tatcagaact gcactttatg
    12241 acgcaaagta tcaagcattg cttgttaata gaaatgaaga agcagatgac agtgtaacta
    12301 tagctggaaa attatgtgag tctggtgata tcattattaa agacgctaaa ttaccttcat
    12361 cagtcaaacg tggagactat cttgctatat tatcaactgg tgcatatcat tactctatgg
    12421 catccaatta caatcaaatg caaaagcctt ctgtgttttt cttaaaagat ggcaaagcac
    12481 gtgaagttat aaagcgacaa tcgttaagac aactcattat taatgataca aaataaaaat
    12541 aaacaaagta atccccgaag cacagaaaat tatactgtga ctcggggaat ttttatgcat
    12601 tatagatgac tgtagaaaac atgcttggac atatactcta aaaaaggaag aacagcacat
    12661 ttttagttag aaagtattta tttctttttg tcattaatcc tttatattta gttagcccta
    12721 ttcaactaat ttaaagcatc atatacatac cacactttaa acaagcatca tgaaattaga
    12781 ttttatgctt tacttgcttt ttcaaataat ataaaacgat aagaattaac aacaaatata
    12841 atgtataaaa cagaatttca tcaaatccaa aatctttact tgtaattaat acatcaatat
    12901 cttctaattc catcatctct gctttaatat aattattaaa ctttggcaaa gtcattaaat
    12961 gtacattgta aatatagtaa taaaagtcga taaatatgat gttaaaaaat atgtatgttt
    13021 tatcaatatt agttttgaaa aatagtatcc cagaaatcat tatcggaatc actaatacaa
    13081 tcatcattgc tgctaaaata ttaatattta atccaattgc agataataca ccgaaaacta
    13141 ataaattagc aactaaacta aggataagat atttcataaa atcacctcgt cgttgtacac
    13201 cataattata ttatataaat ataattttct attgcaaaca atgttggtga tataaaaaaa
    13261 gagttctcaa tttggctgag aaactcatcg cgttaagtat ttgtaataag catataaaaa
    13321 caccttactt cttggtaagg tgttagttaa aatcaatgat tcaaatctaa gaattatagt
    13381 ttaacaacgt ttgcagcttg tggaccgcgg tcgccttcaa ctacttcaaa ctcaacagct
    13441 tgaccttctt ctaatgattt gtaaccatct tggttaattg ctgaaaaatg tacgaatacg
    13501 tcattttctc cttcaacttc gataaagccg aatccttttt cagcgttaaa ccatttaact
    13561 gtaccttgtt tcataatctg aaacctccaa gactaaaatt cattcaatat gcttattcgc
    13621 atattacaaa aaatacatgc aaatttcact caaatattct ttgcaatatg gaataatcat
    13681 ctgcttaact tgtattatag tgcagttatt accaaattgc aatacaataa taaaaaatat
    13741 tcatttaatc aattattggt agtttataat atacttcatt attttgtaaa acaatgaaac
    13801 tataaaatat ttgtaaatcc tcttcacaat cttcgcaata gttcatgtca caattattat
    13861 aaaatgcata aatattatat ttgcctgtga cataattatc gaactgaact ttacattgat
    13921 taatcaattg ttgatagtgc ttaaacatgt catcaaaatc ttgatattga tatttttcaa
    13981 caatgttttc tggccagtca ctgaataacc accatccctc ataatcggct ctaattttgg
    14041 taactgtcca cattattaaa gaccccttcc atacttcaaa aactctatac ttatttttat
    14101 acctttatcc tctgaaaatc aagtttgacg acttgaaaca aacaaagtag taactatagt
    14161 aattattagt ttttttaagt aaaactacgt ataataacat tatgaggtgg taaaaatgag
    14221 acatatacat ttacaagtat tcggacgcgt tcaaggcgtc ggatttagat attttacaca
    14281 acgcattgca atgaactata acattgtcgg tactgttcaa aatgtagatg actatgtaga
    14341 gatatatgca caaggggatg acgcagatat agagagattt attcaaggtg taattgaagg
    14401 tgcctcacca gcatcaaatg taacaagcca tcaacttgaa gagttagaac taaatcaaaa
    14461 attatcggat tttcgatcaa tataaaatgc taaataaagg aagatgacag tgagatataa
    14521 tatttctcat atatttgggg tgttagtggg aattcctgta gcgtttttaa caagcatatt
    14581 tgggatgatt gcacttgatg tatctttttt aattgatatg tctattggta ttgttggctt
    14641 tttaatgaca tacctaccga tacaaaaact cacttcacgc aaatatttaa acgaaattgg
    14701 tttgactaga aaagactatc gctatattcg aaatcagtta aatcatacac accaaaaact
    14761 tagaggtatt ttaaaaacgt atgtcaatat aagatcaatt aaagatttta ggcagattaa
    14821 tgatatatac caaatttcac gttctattta tacgacagtt agacagagac ctgcatcatt
    14881 ttataaagtt gaaggctttt tttattctca tattgataat gctttaaatt tggttgatgc
    14941 atatacacgt ctagcaaaaa tgcccaaaaa atcaattaat gaacagcaaa agttagaaca
    15001 aacacgaatt actttggatg aggtcaaacg aacattaatc gctgatttaa agcgtctcaa
    15061 cgaagatgat tatgaacgtt tagatattga aatggaatta aataagttac atcaaaaaca
    15121 tcatcaagat tgatgtaaaa tagcaactat tggagagatg attgatgact gaaaataaaa
    15181 gtttcaaaga aagccatcca ctagatgatt ttataagcga taaagaatta tcgaatacta
    15241 ctattcaaaa agaaaagtta acaattgaac aacaaaaaca ggtagacaca atcagtaaac
    15301 aaattaaccc tttagacaat gaaggtttat tagcgtttgg ttctgattta cagaaacaaa
    15361 tgtctcaatt ttcacatcaa atgttggatg aagtacaaag taaagatgtt ggtcctattg
    15421 gagatacttt gtcagatcta atgtcaaaac taaagtcagt taatccaaat gagttaaata
    15481 ctgataaacc atctatgtta aaaagaattt ttagcagagc aaagtcgtct atcaatgaaa
    15541 tcttttcaag aatgcaatca gttagtgctc aagtcgatcg cataacgatt caactgcaga
    15601 aacatcaaac acatttaaca agagatattg aattattaga tacgctatat gataaaaaca
    15661 aacaatactt tgatgactta tcattgcata tcattgctgc acagcaaaaa aagttgcaat
    15721 tagaaaatga aaagctacca caattgcaac agcaagcgca gcaatccact aatcaaatgg
    15781 atattcaaca agttgcagat atgcagcaat ttatagatag actagataaa cgcatatatg
    15841 acttacagct ttcaagacaa atagctttgc aaactgcgcc acaaattcgt atgattcaaa
    15901 atgttaatca agcacttgcc gagaagatac aaagttcaat tttgacaagt attccactat
    15961 ggaaaaatca aatggccatt gcgcttacat taatgagaca gcgtaatgca gttgctgcac
    16021 aacgagctgt cactgataca actaatgatt tattaacagc aaatgctgaa atgttgaaac
    16081 aaaatgcgat tgaaactgca acagaaaatg agcgtggcat tgttgatctt gatacattga
    16141 aacgtacaca gcgtaacatt attgagacaa ttgaagaaac attaattatt caacaacacg
    16201 gtcgcgaaga acgacaatta gctgaaaaag aattacaaca attagaacaa gatttaaagt
    16261 cacatttagt gaacatcaaa ggaccgaata aacaatcata aattacgaat tagatataac
    16321 aaaaaggaag catcctacga ttaaattgga gatgcttcct tttatattat tcgttattcc
    16381 tgttgatatt taattggatc ttgttttaca aatatgccga ctagatagcc taatatcgtt
    16441 gcaataattg ctactgggaa ccactctaaa gaatacgctc ttagaggcaa tgattctata
    16501 aagttaattt tcagccaacc taacttacta ataacactga aaatcgacaa tataaatacg
    16561 ataataactg gaatttgttg tgaaatgcgt tttgtcggta tgaatttggc aattaaaatt
    16621 aataatacaa cagttattgc tactgggtat acaatgctta ataccggaat tgacattgag
    16681 ataacagcat ttaaaccttg gttagcaata ataaaactca ttaaaatgaa aactaataca
    16741 aatgctttgt atgatacttt aggtacgatt ctatggaaat attcagaaac tgcaacaata
    16801 agcccgcatg ctgtagttag acatgccagc gccacaatga tgcccaataa atattttccg
    16861 aatgaaccaa atcctgttga agccattgtc gttaataaat atgtcccaat gtttcgatct
    16921 ttggatttca attgatctaa cgtcatgtca cttactggca tatgattacc aatataacct
    16981 aatgaaatat atatgaaaat taaagctacg gctgcaatta aaccagcagt caaagtttgt
    17041 ttgaatattt gatttgtttt agtaatgcct gttagtttta ctgcattaac aacaatcatt
    17101 gaaaaagcaa ttgctgcaat ggcatccatt gttaaatagc cttgtgtaaa gccttcagca
    17161 aaacttgaaa aattagaatg atatagtgct tcattgccct ttccagcact attaccgcta
    17221 aagtctaagt atcctttaat aatcatcgct aaaatagtaa tcaataataa tggtgttaat
    17281 aatgaaccaa tacgatcgat taacttagat ggatttaaac aaatatacaa aacgactatg
    17341 aagtagataa tcgtaaatat aaataaagcg atactactat tgctatgtat aattggtgta
    17401 attgtcattt caaaagatgt agatgcagtt ctaggtattg cgaaaagtgg tcctatagtc
    17461 aaataaatga tgattaagaa caatattgaa aatttaggtg aaattttatt taatgcgcca
    17521 atatatcctt ctttatcaag tgcacctaca atcacaccta ataatggtaa accaatccca
    17581 gttagaacaa acgctaaaat ggcgggccag aaaaattgac cactatccaa tccgagatta
    17641 ggaggaaaaa ttagattgcc tgcgccaaaa aacatagcga agagcgtaaa cccaatgacc
    17701 catgtatttt tattcataga gttactcctt tttttaaaac acgaaataat ttacaagtaa
    17761 atattttagc acaaaaaata ataaagagtc tatatgaaat atgttgtaca tagcagaaac
    17821 aaaacacatg tgttgtttaa atcaaattat gccagaaaat aaaattcttc aaattcactt
    17881 tttaaatagt aactgatgac ttttattcac aatttcatat aaactcatat tttaaactta
    17941 tttataaaga tttaagtagt aattttttta ataatggaga gagatgtcca ggtaaatgcg
    18001 caacaccttc aacgaaaata gcatattgac cataaatatt atgaattgtt tgttcaacat
    18061 cttcagttat tggatcttga ctcaaaaata cattaaatac ttcaatacca aatttacgtg
    18121 acatttctac agcttcatac gtatcaataa taccatcttg actataatta aatgcagacg
    18181 gttcgccgtc tgaaaatacg attaaaaatc gttgatgttg atttcgacgc attaatcgtt
    18241 cacttgcaac tctaatagca acaccatcac gattatcatc ttgaggttca agtgccataa
    18301 tacgtgggcc atctttttca aaggttgagt aatcatagtt aataatttca ttaatgatat
    18361 ttggttgtgc atgatcgtct gaatcaaagg catcctcact gaatgataaa atttcatgtt
    18421 taatgttcaa tgcttttaac gtctcgtgga ataacactac acctttcttc gtttcagcca
    18481 ttttatcatg catacttgct gacgcatcaa ttaacaatgt aaacgtcgca tcaaatgatt
    18541 tacttaaatc ttgttttttg taaaacaatt tatattgatc gtcgataaac caattaatta
    18601 aatccttttg taatcgccct tttgttaaat taaaacgtgc atctcgttgt tctcgttcaa
    18661 tcgttttctt tataatttga attaagtctt tgatttcata ttgtacgtct tgtttcgatt
    18721 cttgatattc taaaacatat tgtggctcaa tttcaggaat ttgccatttt atttctacat
    18781 ttttgttcac accatcaagt tgaaatgctt ggctttgacc aacagcatcg ccttcttcac
    18841 gatttagcgt atcgtttgat cctttgccct ttttggtcat catatcagtc atatcatctg
    18901 tagcatcgcc ttcacgtgct tcatcattac ctaatgtttc actattttgt ccttcgtgaa
    18961 gctccatttc taaataggcg ccaccttttg actcactatc tgcagattta gagtcagctt
    19021 tttcactttc gttatcatca tcttctgaag tatcatcttg cccatcgact tgacttgcat
    19081 cagttctctt taaatcatca aactctggac tagctaatgt attatatagt gttttaggta
    19141 agtaataata ttcgtttagc atatcttctt ttaaaatatc atctacttga tacataattc
    19201 tttgagccag atacatatta tcttcagaat tttgattttg gaaaaaatta ggtaaatata
    19261 agaacatatt tactaaaata tcatctaaat ctgaatgtat agatggtata tcaaagaaat
    19321 cttgacttaa aaatgcatgt tctaaataca aaaataataa atctgtatat tgtgttttag
    19381 tacgatacac tttaatttga gattccgtat atgatacccg tgtatctaag cgaagatcaa
    19441 ttaatttagc agtacttggg cgctcaactt taatagaatt taatacgcgc atatcttcta
    19501 ataatttaaa aagttgttga taaaatttag ggtgtttaaa agttttatct tgtactactt
    19561 catttacaat ttgtacatcc atcatatgat aaccgtaagc agctaacata acatctgttt
    19621 ttaaaccagc catttcgata tggcttggtc gatgtgacca aaaccaactc gtaatcaaaa
    19681 cattttgaac aggattatag taagggaatt tttggatttt aacttgtgtt tgttcatttt
    19741 ttaataagag tcgagctaag tcttgcaaca tcattacttg cttggcatct aactgttcgt
    19801 cgttaaattt tatgaaacga tcactcatgt tttatccctc tttaaaagtt tagttctaca
    19861 gcattatata ttgcttgttg ttcacgttca tcttccaatt tatcaataat tgtacgttta
    19921 attgcacgtt caactggcat tacagtgatt aaatcacaca agtctaataa tgcacggata
    19981 ctagcggctt cttcagaaat ttgtccctgc ttagacatag tacgtaaatc ttcgttaaac
    20041 ttaataattt gttcgatttg tttatcatct tgtaataaac tttgctcttt aatcacattt
    20101 tttaaaatgt ccccgtcaat ataatcaacg tgaataacaa caaagcgatt ttttagtgct
    20161 tcattcattg gcaaagtacc aacataacct tcatttatcg ctgctataac gttaaatcct
    20221 ggtacagctt tgattacttc accagtgtat ggattcgtaa tttgacgacg ataatctaat
    20281 acaccattta atacaggcaa tgtttcaggt ttagccatat ttatttcatc aatatataaa
    20341 atatgcccct ctttcatagc tttaataact ggaccatcta caaagacaat ttcttgttga
    20401 ccttccgcat ttgttttaat tgttttaaag cctaataagc tttctgtatc taaatcaaca
    20461 gaacaattga cttgatgcat gggtgtatca acaacttcac ttaatgtttc tgccaacttt
    20521 gttttccctg aacctgttgg acctttaagt aaaatatttt tatttaaatc aaataatgcc
    20581 ttcgcatcat tgaaaactgt tgaatctgaa ttcttataat gttttagtgc cattttaaaa
    20641 cgttctcctt taaataaatt aaaaaactaa gacatggaat aagttcttca aatgccttag
    20701 tttactattc tattctgata taaaacgcaa tacttagtat gcgaattgtt tatattttac
    20761 caaatttact aattgaaaat ctcatattag gcttcatttc aataattatg cgtttaaact
    20821 tctttgaaat atgttttata gtaaccgcca actaatccag aattatctat tatttgataa
    20881 tattcttcag tttcgttgat aacatcatat tgtttgccaa ccgttaacat gtcagaaact
    20941 gtaaatttct ttgcatctgt attaatgact tctactttct tgattggtgt acgttctttc
    21001 caagtttcat gtaacataaa ttttgtcctc actatcgtaa aaaaattatt tttgtaaagt
    21061 gaatataaac gataatccac tgttttcagt aattctaatt gattcaatat catcttgctc
    21121 aagcgtttga tatggtattt ccacttcatc taagcgcgat ttcgcttgat taaagaaatc
    21181 tgcatctttc gtttcaaact caacttgatc gactgcgcca tattccggca ttgtcatttc
    21241 tgtttctaca ggcattaaat gtatttcgcc acctagacca cccgttccaa ctttgaatac
    21301 ttggacatga tagtcagcat tgtcgaaggg ttggtattct gcaaatactt caagtccgaa
    21361 tatatttgtt aaaatttgac ctgtaatatc tacatgattc actttaagaa tcactggtcc
    21421 taaaccttgc acttgatgta acggattgac cgcactctca aaagaaggca tacctaaacc
    21481 aacgccataa ttattctcgt ttgaatatat tgagaaaata tgaccattgt tatcttcgag
    21541 actgaaatat ttattgccat ttaattcttt aactgttgta aatggaatat ccttattcga
    21601 taatatttcc gcatactcct ctaaacctga gtcagttggt gtacgtaatc caatacccac
    21661 aaagtgagat tcttctaatt gctcacttgg aacttgtata aattgaagtc ttgttcctgg
    21721 gcttatatct gcatcgccga aacgaattga gttttcaaga agttcttcat aatttaatcc
    21781 taatatgtca accatgaaat gttttgtctg ttctatattt gttgtaccta atgttatact
    21841 tctaagtcca cacattatag ccacctctat ctttatcttt actattatat tataacttat
    21901 tttaatcata aattatagaa tatcggtcag ttgattttga ttatagatta atatgtgaaa
    21961 aatgtatttc tttaaaagaa ctatttcatt taaataggta acataatatt gttatggttg
    22021 ctattgagta tgtcattaat gagtatctgt atatagcaat tgaatatttc gttttatgta
    22081 gtacataaaa aacatataca tgtcgtatcc ataaagtgaa tttacatctt gttcagatga
    22141 ttttaaatta actaaaggcg cttatagaat tcataaattt catcgcttgt tattatctaa
    22201 aatgatttca ttagcatatt gaaacacgcc attccaccta tatttctatt gtgagtctat
    22261 ttcaataaaa atgatatatt ttttaagttg
//
LOCUS       DAPDIM010000046        21837 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000046 DAPDIM010000000
VERSION     DAPDIM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21837
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.046"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..637)
                     /locus_tag="RFE25_001888"
     CDS             complement(<1..637)
                     /locus_tag="RFE25_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDU2816938.1"
                     /translation="MKNTLYHQLYEKLKKQIIEGQFKEGDKFYSKRQLSKHLSISQTT
                     VEHAYQLLLDEGYIYSRPRSGYFVSEIESLTILNNQPIPSLFDDDSYKPKASDEAYDY
                     AFNLDEIDTKHFPIELFRKYSKDLYDTNHLNQLRRGHFQGELHLRFQLAFYLFTNRGV
                     ICDPNQIIIGSSTEQLVNQLVDLLYTSTFIIEKPSYPPIKNILDKKQVEYEQ"
     gene            741..1628
                     /gene="pdxS"
                     /locus_tag="RFE25_001889"
     CDS             741..1628
                     /gene="pdxS"
                     /locus_tag="RFE25_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011303857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HDU2816939.1"
                     /translation="MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVM
                     ALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYI
                     DESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVE
                     AVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVAT
                     PQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAM
                     KGLDINQLSLEERMQERGW"
     gene            1632..2192
                     /gene="pdxT"
                     /locus_tag="RFE25_001890"
     CDS             1632..2192
                     /gene="pdxT"
                     /locus_tag="RFE25_001890"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HDU2816940.1"
                     /translation="MKIGVLALQGAVREHIRHIELSGHEGIAVKKVEQLEEIEGLILP
                     GGESTTLRRLMNLYGFKEALQNSTLPMFGTCAGLIVLAQDIVGEEGYLNKLNITVQRN
                     SFGRQVDSFETELDIKGIATDIEGVFIRAPHIEKVGQGVDILCKVNEKIVAVQQGKYL
                     GVSFHPELTDDYRVTDYFINHIVKKA"
     gene            complement(2400..3614)
                     /locus_tag="RFE25_001891"
     CDS             complement(2400..3614)
                     /locus_tag="RFE25_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDU2816941.1"
                     /translation="MHILIGIIGIIFFLALAFLFSSDRKNIRWKYVGILLAIQLIFAF
                     ILLKTTMGIKVIGGISNGFNYLLLKAADGVNFVFGGIQYIDPKQPPFFFSVLLPIVFI
                     SAIIGILQYTKILPLIINVLGFLISKINGMGRLESYNAVAAAILGQSEVFISIKKQLP
                     YIPKQRLYTLTASAMSTVSASIIGAYFTLIEPKYVVTAVVLNLFGGFIIASIINPYKV
                     NEEDDKLLVEETEERQQSFFEMLGEYILDGFKVAVIVGAMLIGYIAIIALLNGIVSNI
                     FSTVSGGAISWDFQTLIGFVFAPFAFLVGVPWQDAVQAGSVMATKLLSNEFVAMQALG
                     KLSDLSEHAKGVTSVFLVSFANFSSIGIISGAIKSLNDKKGDTVARFGLKLLFGATLV
                     SFISAAIAGFFI"
     gene            3772..4233
                     /locus_tag="RFE25_001892"
     CDS             3772..4233
                     /locus_tag="RFE25_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000551761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDU2816942.1"
                     /translation="MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNY
                     VIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYII
                     DGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY"
     gene            4252..4818
                     /locus_tag="RFE25_001893"
     CDS             4252..4818
                     /locus_tag="RFE25_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000882074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDU2816943.1"
                     /translation="MLCENCQLNEAELKVKVTSKNKTEEKMVCQTCAEGHHPWNQANE
                     QPEYQEHQDNFEEAFVVKQILQHLATKHGINFQEVAFKEEKRCPSCHMTLKDIAHVGK
                     FGCANCYATFKDDIIDIVRRVQGGQFEHVGKTPHSSHKKIALKRKIEEKNEYLKKLIE
                     IQDFEEAAIVRDEIKALKAESEVQHDDA"
     gene            4808..5815
                     /locus_tag="RFE25_001894"
     CDS             4808..5815
                     /locus_tag="RFE25_001894"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDU2816944.1"
                     /translation="MTHNIHDNISQWMKSNEETPIVMSSRIRLARNLENHVHPLMYAT
                     ENDGFRVINEVQDALPNFELMRLDQMDQQSKMKMVAKHLISPELIKQPAAAVLVNDDE
                     SLSVMINEEDHIRIQAMGTDTTLQALYNQASSIDDELDRSLDISYDEQLGYLTTCPTN
                     IGTGMRASVMLHLPGLSIMKRMTRIAQTINRFGYTIRGIYGEGSQVYGHTYQVSNQLT
                     LGKSELEIIETLTEVVNQIIHDEKQIRQKLDTYNQLETQDRVFRSLGILQNCRMITME
                     EASYRLSEVKLGIDLNYIELQNFKFNELMVAIQSPFLLDEEDDKSVKEKRADILREHI
                     K"
     gene            5829..8285
                     /locus_tag="RFE25_001895"
     CDS             5829..8285
                     /locus_tag="RFE25_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDU2816945.1"
                     /translation="MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEG
                     IAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNF
                     VGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNT
                     PTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIA
                     EGLAQAIVNNEVPETLKDKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVIL
                     FIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKNIEKDAALERRF
                     QPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAI
                     DLIDEASSKVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLE
                     KQYEEAKNEWKNAQNGMSTSLSEEDIAEVIAGWTGIPLTKINETESEKLLSLEDTLHE
                     RVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDD
                     DAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHP
                     DVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDY
                     ETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELKEIVTMMVNKLTNRLSEQNIN
                     IIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDG
                     KEFKYDIAEQTSETKTPSQA"
     gene            8770..10134
                     /gene="radA"
                     /locus_tag="RFE25_001896"
     CDS             8770..10134
                     /gene="radA"
                     /locus_tag="RFE25_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDU2816946.1"
                     /translation="MAKKKVIFECMACGYQSPKWMGKCPNCGAWNQMEEIVEKAANPK
                     HGVKTKELAGKVQKLNSIKHETTPRVLTDSAEFNRVLGGGIVSGSLVLIGGDPGIGKS
                     TLLLQICASLSQKKKVLYITGEESLSQTKLRAERLDEDSSELQVLAETDLEVIYQTVK
                     EEQPDLLVVDSIQTIYHPEISSAPGSVSQVRESTQSLMNIAKQMNIATFIVGHVTKEG
                     QIAGPRLLEHMVDTVLYFEGDEHHAYRILRAVKNRFGSTNEMGIFEMKQSGLKGVNNP
                     SEMFLEERSTNVPGSTIVATMEGTRPLLIEVQALVTPTTFNNPRRMATGIDHNRLSLL
                     MAVLEKKENYLLQQQDAYIKVAGGVKLTEPAVDLSVIVATASSFKDKAVDGLDCYIGE
                     VGLTGEVRRVSRIEQRVQEAAKLGFKRVIIPKNNIGGWTYPEGIQVIGVTTVHEALSF
                     ALHS"
     gene            10159..11232
                     /locus_tag="RFE25_001897"
     CDS             10159..11232
                     /locus_tag="RFE25_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017328539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDU2816947.1"
                     /translation="MNIVKLMVIIIYLIIGSALGIIIIPEIANDLGLQNSSFLKNHYV
                     DGIIGSIFMFLIFGVFIRRVTNAIKGLEHFIMRRSAVEILFATIGLIIGLLISVMVSF
                     ILESIGNSIFNHFIPVIITILLCYFGFQFGLKKRDEMLMFLPENIARSMSQHTKSATP
                     KIIDTSAIIDGRILEVIRCGFIDGNILIPQGVINELQIVADSNDSVKREKGKRGLDIL
                     NELYDLDYPTKVIHPTKTHSDIDTMLLKLAKQYHASIITTDFNLNKVCHVHGIKALNV
                     NDLSEAIKPNVHQGDQLHILLTKMGKEPGQAVGYLDDGTMVVVDNAKNLIGSHVNLEV
                     VSLLQTSSGRIVFAKKIEDTVSL"
     gene            11789..13243
                     /locus_tag="RFE25_001898"
     CDS             11789..13243
                     /locus_tag="RFE25_001898"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDU2816948.1"
                     /translation="MSDRIRVRYAPSPTGYLHIGNARTALFNYLYAKHYNGDFVIRIE
                     DTDKKRNLEDGETSQFDNLKWLGLDWDESVDKDNGYGPYRQSERQHIYQPLIDQLLAE
                     DKAYKCYMTEEELEAEREAQIARGEMPRYGGQHAHLTEEQRQQFEAEGRQPSIRFRVP
                     QNQTYSFDDMVKGNISFDSNGIGDWVIVKKDGIPTYNFAVAIDDHYMQISDVIRGDDH
                     ISNTPKQIMIYEAFGWEPPRFGHMSLIVNEERKKLSKRDGQILQFIEQYRDLGYLPEA
                     LFNFIALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPAFFDKQKLAWVNNQYMKQKDT
                     ETVFQLALPHLIKANLIPEVPSEEDLSWGRKLIALYQKEMSYAGEIVPLSEMFFKEMP
                     ALGEEEQQVINGEQVPELMTHLFSKLEALEPFEAAEIKKTIKEVQKETGIKGKQLFMP
                     IRVAVTGQMHGPELPNTIEVLGKEKVLNRLKQYK"
     gene            13666..14313
                     /gene="cysE"
                     /locus_tag="RFE25_001899"
     CDS             13666..14313
                     /gene="cysE"
                     /locus_tag="RFE25_001899"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDU2816949.1"
                     /translation="MILLKRMRDDIKMVFEQDPAARSTLEVITTYAGLHAVWSHLIAH
                     KLYNQKKYVAARAISQISRFFTGIEIHPGAKIGKRLFIDHGMGVVIGETCTIGDNVTI
                     YQGVTLGGTGKERGKRHPDIGDNVLIAAGAKVLGNIKINSNVNIGANSVVLQSVPSYS
                     TVVGIPGHIVKQDGVRVGKTFDHRHLPDPIYEQIKHLERQLEKTRNGEIQDDYII"
     gene            14297..15697
                     /locus_tag="RFE25_001900"
     CDS             14297..15697
                     /locus_tag="RFE25_001900"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDU2816950.1"
                     /translation="MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPA
                     INYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGA
                     LNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
                     DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWNSPFGEGRPGWHIECSVMAFHELGP
                     TIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILV
                     HDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRNSYQLIEERAQIATN
                     IENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDK
                     FKAVYQIFSDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQ
                     NIILEDTPQGVRFKRG"
     gene            15690..16094
                     /locus_tag="RFE25_001901"
     CDS             15690..16094
                     /locus_tag="RFE25_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDU2816951.1"
                     /translation="MDNQQDNHIKLLNPLTLAYMGDAVLDQYVRTYIVLKLKSKPNKL
                     HQMSKKYVSAKSQAQTLEYLMEQEWFTDEEMDILKRGRNAKSHTKAKNTDVQTYRKSS
                     AIEAVIGFLYLEKREERLEALLNKIITIVNER"
     gene            16102..16848
                     /gene="rlmB"
                     /locus_tag="RFE25_001902"
     CDS             16102..16848
                     /gene="rlmB"
                     /locus_tag="RFE25_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDU2816952.1"
                     /translation="MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAK
                     DQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYADFDQFLKQQKEKEGLSTVLILDG
                     LEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKT
                     IDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPM
                     VGHVNSLNASVAASLMMYEVFRKRHDVGEI"
     gene            16848..17372
                     /locus_tag="RFE25_001903"
     CDS             16848..17372
                     /locus_tag="RFE25_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDU2816953.1"
                     /translation="MKERYLIIDGYNMIGQSPTLSAIAKENLEEARMQLIDAIANYNA
                     VISDEIICVFDAYDQSGVEREYMYHGVKTIFTKEKETADSFIERYVYELYDKHTKHIA
                     VVTSDMSEQHAIFGSGAYRISSREMWRDLKENEIDVSKSLDDISENKPRTRIPLSSEI
                     LAEFEKIRRGHHKK"
     gene            17453..18022
                     /locus_tag="RFE25_001904"
     CDS             17453..18022
                     /locus_tag="RFE25_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDU2816954.1"
                     /translation="MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFN
                     HYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQCLITSVKYDYLRKYLATNKRMDN
                     LINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
                     AQLMHVKEKVIYNAIQRCKNKIKRYFKMI"
     gene            18137..18280
                     /gene="rpmG"
                     /locus_tag="RFE25_001905"
     CDS             18137..18280
                     /gene="rpmG"
                     /locus_tag="RFE25_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002451211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDU2816955.1"
                     /translation="MRKIPLNCEACGNRNYNVPKQEGSATRLTLKKYCPKCNAHTIHK
                     ESK"
     gene            18336..18518
                     /gene="secE"
                     /locus_tag="RFE25_001906"
     CDS             18336..18518
                     /gene="secE"
                     /locus_tag="RFE25_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499089.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDU2816956.1"
                     /translation="MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFF
                     YALDLGITALKNLLFG"
     gene            18531..19079
                     /gene="nusG"
                     /locus_tag="RFE25_001907"
     CDS             18531..19079
                     /gene="nusG"
                     /locus_tag="RFE25_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDU2816957.1"
                     /translation="MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVV
                     IPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSK
                     PNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLT
                     VLVDMFGRETPVEVEFDQIEKL"
     gene            19260..19682
                     /gene="rplK"
                     /locus_tag="RFE25_001908"
     CDS             19260..19682
                     /gene="rplK"
                     /locus_tag="RFE25_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012664221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDU2816958.1"
                     /translation="MAKKVDKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNA
                     RTQDQAGLIIPVEISVYEDRSFTFITKTPPAPVLLKKAAGIEKGSGEPNKTKVATVTK
                     DQVREIANSKMQDLNAADEEAAMRIIEGTARSMGIVVE"
     gene            19890..20582
                     /gene="rplA"
                     /locus_tag="RFE25_001909"
     CDS             19890..20582
                     /gene="rplA"
                     /locus_tag="RFE25_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDU2816959.1"
                     /translation="MAKKGKKYQEAASKVDRTQHYSVEEAIKLAKETSIANFDASVEV
                     AFRLGIDTRKNDQQIRGAVVLPNGTGKSQSVLVFAKGDKIAEAEAAGADYVGEAEYVQ
                     KIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGK
                     VEYRAEKAGIVHASIGKVSFTDEQLIENFNTLQDVLAKAKPSSAKGTYFKSVAVTTTM
                     GPGVKIDTASFK"
     misc_feature    20670..20816
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            20854..21354
                     /locus_tag="RFE25_001910"
     CDS             20854..21354
                     /locus_tag="RFE25_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDU2816960.1"
                     /translation="MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQ
                     LREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKD
                     HEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQ
                     KEENAE"
     gene            21397..21765
                     /gene="rplL"
                     /locus_tag="RFE25_001911"
     CDS             21397..21765
                     /gene="rplL"
                     /locus_tag="RFE25_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDU2816961.1"
                     /translation="MANHEQIIEAIKEMSVLELNDLVKAIEEEFGVTAAAPVAVAGAA
                     GGADAAAEKTEFDVELTSAGSSKIKVVKAVKEATGLGLKDAKELVDGAPKVIKEALPK
                     EEAEKLKEQLEEVGATVELK"
BASE COUNT         8096 a         2980 c         4224 g         6537 t
ORIGIN      
        1 tttgttcata ttcaacttgt tttttatcta aaatattttt gattggtgga taactaggtt
       61 tttcgataat aaacgttgaa gtataaagta aatcgactaa ttgatttact aattgttcgg
      121 tagatgagcc aattataatt tgattaggat cacaaattac accacgatta gtaaataaat
      181 aaaatgccag ttgaaatctt aaatgtaatt ctccttgaaa atgtcctcta cgtaattgat
      241 ttaaatgatt tgtatcataa agatctttgg aatactttct gaaaagttct atagggaaat
      301 gtttcgtatc tatttcatcc aaattaaaag cataatcata agcttcatca ctcgcttttg
      361 gtttatatga atcatcatca aaaagagagg ggataggttg attgtttaaa attgttaaag
      421 attcaatttc ggacacaaaa tatccagagc gaggtcttga ataaatgtaa ccttcgtcta
      481 atagaagttg atatgcatgc tctacggttg tttggctgat agataaatgt ttgcttaatt
      541 gtcttttaga ataaaattta tcgccttctt taaattgacc ttcaattatt tgttttttta
      601 atttttcata aagttgatgg tataaagtgt ttttcaattt tataactgac ctcctaaatt
      661 tatcttattt tgtacctttt taaatatcag tttatacatt acaatgtatt taatcaactt
      721 gaaaaggggt tttatgtata atgagtaaaa ttattggatc agacagagtc aaaagaggta
      781 tggctgaaat gcaaaaaggc ggcgttatta tggatgtcgt taatgctgag caagcaagaa
      841 ttgcagaaga agcaggcgcg gtagcagtta tggcattaga acgagtacct tctgatatta
      901 gagctgctgg tggcgttgca cgtatggcaa accctaaaat tgtagaagaa gtaatgaatg
      961 ctgtttctat tccagtcatg gctaaagcac gtattggtca tatcactgaa gcaagagtat
     1021 tagaggcgat gggtgttgac tatattgatg aatcagaagt gttaacacca gcagatgagg
     1081 aatatcactt aagaaaagat caatttacag taccatttgt atgtggatgt cgtaatttag
     1141 gtgaagctgc gcgtagaatt ggtgaaggtg ctgctatgtt acgtactaaa ggtgaaccag
     1201 gtacaggtaa tattgttgaa gctgtaagac atatgagaca agttaattca gaagttagtc
     1261 gattgactgt aatgaatgat gatgagatta tgacttttgc gaaagatatc ggtgcgcctt
     1321 atgaaatttt aaaacaaatt aaagacaatg gtcgtttacc ggtagttaac tttgcagctg
     1381 gtggcgttgc gactcctcaa gatgctgctt taatgatgga attaggtgct gacggtgtat
     1441 tcgttggatc aggtattttt aaatcagaag atccagaaaa atttgctaaa gcaattgttc
     1501 aagcaacaac acattaccaa gactatgaac taattggaag attagcaagt gaacttggca
     1561 ctgctatgaa aggtttagat atcaatcaat tatcattaga agaacgtatg caagagcgtg
     1621 gttggtaaga tatgaaaata ggtgtattag cattacaagg tgcagtacgt gaacatatta
     1681 gacatattga attaagtggt catgaaggta ttgcagttaa aaaagttgaa caattagaag
     1741 aaatcgaggg cttaatatta cctggtggcg agtctacaac gttacgtcga ttaatgaatt
     1801 tatatggatt taaagaggct ttacaaaatt caactttacc tatgtttggt acatgcgcag
     1861 gattaatagt tctagcgcaa gatatagttg gtgaagaagg ataccttaac aagttgaata
     1921 ttactgtaca acgaaactca ttcggtagac aagttgacag ctttgaaaca gaattagata
     1981 ttaaaggtat cgctacagat attgaaggtg tctttataag agcgccacat attgaaaaag
     2041 taggtcaagg cgtagatatc ctatgtaagg ttaatgagaa aattgtagct gtccagcaag
     2101 gtaaatattt aggcgtatca ttccatcctg aattaacaga tgactataga gtaactgatt
     2161 actttattaa tcatattgta aaaaaagcat agcttaatgt atgctaaatc aacgaattat
     2221 tgatatttat agatttgttg agaagaaaat atctccttca aacttagctt tggaggagtt
     2281 attttttatg tcaaaattaa aaatgataaa aaataaagat atacataaga aaaaacccct
     2341 tcaaagagac tgagaatagt caaaattttg aagggattaa ttcgatgttg atgtatttgt
     2401 taaataaaga atccagcgat tgcagctgaa atgaaagata ctagtgttgc accgaataat
     2461 aatttcaaac caaagcgggc aactgtatct ccttttttgt cattaagtga tttaatagca
     2521 cctgaaataa taccaataga gctaaagtta gcaaatgata ctaagaatac agatgtaaca
     2581 ccttttgcgt gttcagataa atcactaagt ttaccaagtg cttgcattgc tacaaattcg
     2641 ttagataata gttttgtcgc cataactgaa ccggcttgaa ctgcatcttg ccatggcaca
     2701 ccgactaaga atgcaaatgg tgcaaagaca aaaccaatta atgtttggaa atcccaagaa
     2761 atagcgccac ctgaaactgt actaaagata ttgcttacaa ttccatttaa tagagcgata
     2821 atggcaatgt atccgattaa cattgcacct acaatgacag ctactttaaa tccatctaaa
     2881 atatattctc ctagcatttc gaagaatgat tgttgtcttt cttcagtttc ttcaactaat
     2941 aatttgtcat cttcttcatt aactttataa gggttaataa ttgaagcgat gatgaaacca
     3001 ccaaataagt ttaagacaac agccgttaca acatatttag gttcaattaa ggtaaagtat
     3061 gcaccgataa ttgaagcaga aacagtcgac attgctgaag ctgttaatgt gtataaacgt
     3121 tgcttaggta tgtatggtaa ttgtttttta attgaaataa atacttcaga ttgtcctaaa
     3181 attgctgcag caactgcatt gtatgattct aaacgtccca taccattaat tttagaaatt
     3241 aagaatccta aaacattaat gattaaaggt aaaatctttg tgtattgaag gataccgata
     3301 atcgctgaaa taaatacgat aggtaataat acactgaaga agaatggtgg ttgcttagga
     3361 tcgatatatt gaataccacc gaatacaaag ttaacaccat ctgctgcttt taataataag
     3421 tagttaaaac cgtttgaaat accaccaata accttgattc ccattgtagt tttaagcaag
     3481 ataaatgcaa agataagctg aattgcaagt aaaattccta catatttcca gcgaatattt
     3541 ttcctgtctg agctaaatag aaacgcaagt gctaaaaaga agataattcc gataatccca
     3601 attagaatat gcatatattt ctcattcctt tagttttttc tacaatctat catacaataa
     3661 aatggaaggg ctaacatcat aaatttttga aaatataaaa acaaattaat tgaaaaaggt
     3721 caaaataggt catataatat agtcaaagaa ggtcaaaaag gggtgatata catgcacaat
     3781 atgtctgaca tcatagaaca atacatcaaa cgtttatttg aagagtcgaa tgaagatgtc
     3841 gttgaaattc agagagcgaa tatcgcacag cgttttgatt gtgtaccatc acaattaaat
     3901 tatgtaatca aaacacgatt cactaatgaa catggttatg aaatcgaaag taaacgtggt
     3961 ggtggtggtt acatccgaat cactaaaatt gaaaataaag atgcaacagg ttatattaat
     4021 catttgcttc agctgattgg accttctatt tctcaacaac aagcttatta tattattgat
     4081 gggcttttag ataaaatgtt aataaatgaa cgtgaagcta aaatgattca agcagttatt
     4141 gatagagaaa cgctatcaat ggatatggtt tctagagata ttattagagc aaatatttta
     4201 aaacgtttgt taccagttat aaattattac taaatgaaat gaggtgttga agtgctttgt
     4261 gaaaattgtc aacttaatga agcggaatta aaagttaaag ttacaagtaa aaataaaaca
     4321 gaagaaaaaa tggtgtgtca aacttgtgct gaggggcacc atccgtggaa tcaagctaat
     4381 gaacagcctg aatatcaaga acatcaagat aatttcgaag aagcatttgt tgttaagcaa
     4441 attttacaac atttagctac gaaacatggc attaattttc aagaagtagc gtttaaagaa
     4501 gaaaaacgtt gcccatcatg tcatatgact ttgaaagata ttgcacatgt tggtaaattt
     4561 gggtgtgcta attgttatgc aacatttaaa gatgacatca ttgatatcgt ccgcagagtt
     4621 caaggtggac aatttgagca cgttggaaag acaccacatt cttcacataa aaagatagct
     4681 ttaaagcgaa aaatcgaaga aaagaatgaa tatttgaaaa aacttattga aatccaagat
     4741 tttgaggaag cagccattgt tagagatgaa attaaagcac taaaagctga gagtgaggtg
     4801 caacatgatg acgcataata ttcatgataa tatcagccaa tggatgaaaa gtaatgaaga
     4861 aacaccaatt gttatgtctt ctagaattcg gttagcgcgt aatttagaaa atcatgtgca
     4921 tccactaatg tatgctactg aaaatgatgg atttagagtt ataaatgagg tacaagatgc
     4981 cttgccaaat tttgaattaa tgcgtcttga tcaaatggat caacaaagta aaatgaaaat
     5041 ggttgcaaag catttgatta gtcctgaact aataaaacaa ccagcagccg cagtattagt
     5101 gaatgatgat gaatctttaa gtgtcatgat aaatgaagag gaccatattc gtattcaagc
     5161 tatgggaact gacacgacat tacaggcttt atataatcaa gcttcatcaa ttgatgatga
     5221 attagatcga agccttgata taagttatga tgaacaactt ggttatttaa ctacatgtcc
     5281 taccaatata ggtactggta tgagagcaag cgtgatgcta catttaccag gtctatctat
     5341 tatgaaaaga atgacacgga ttgctcaaac cattaatcgt tttggatata caatcagagg
     5401 tatttacggt gaaggttcgc aagtttatgg acatacttat caagtatcca accaacttac
     5461 acttggtaaa tctgagttag aaatcataga aacattaaca gaagttgtta atcaaatcat
     5521 tcatgatgaa aaacaaatac gacaaaagtt agacacttat aatcaattag aaacacaaga
     5581 ccgtgttttt cgctcgctag gtattttaca aaactgtaga atgataacta tggaagaggc
     5641 ttcttataga ttaagcgaag ttaaacttgg tatagattta aattacattg aattacaaaa
     5701 ctttaaattt aatgaattga tggtagctat acagtcacca tttttattag atgaagaaga
     5761 tgacaaatct gtaaaagaaa aacgagcaga tatactaaga gaacatataa agtaggaggt
     5821 cattatttat gttatttggt agattaactg aacgtgcaca gcgcgtatta gcacatgcac
     5881 aagaagaagc aattcgttta aatcattcaa atataggaac agaacaccta ttattggggt
     5941 taatgaaaga acctgaagga attgctgcaa aagtattaga aagttttaat atcactgaag
     6001 ataaagtaat tgaagaagtt gaaaaattaa tcggacatgg tcaagatcat gttggtacat
     6061 tgcattatac acctagagct aaaaaagtca ttgaattatc gatggatgaa gctagaaaat
     6121 tacatcacaa ttttgttgga acggaacata ttttattagg cttgattcgt gaaaatgaag
     6181 gtgttgcagc aagagttttt gcaaatctag atttaaatat tactaaagca cgtgcacaag
     6241 ttgtgaaagc tttaggaaac cctgaaatga gtaataaaaa tgcacaagct agtaagtcaa
     6301 ataatactcc aactttagat agtttagctc gtgacttaac agtcattgcc aaagacggta
     6361 cattagatcc tgttatagga cgtgataaag aaattacacg tgtaattgaa gtattaagta
     6421 gacgtacgaa aaacaatcct gtacttattg gagagccagg tgttggtaaa actgctattg
     6481 ctgaaggttt agcgcaagcc atagtgaata atgaggtacc agagacatta aaagataagc
     6541 gtgttatgtc tttagatatg ggaacagtag ttgcaggtac taaatatcgt ggtgaatttg
     6601 aagagcgtct gaaaaaggtt atggaagaaa tccaacaagc aggtaatgtc atcctattta
     6661 ttgatgagtt gcatacttta gttggtgctg gtggtgctga aggtgctatc gatgcttcga
     6721 atattttgaa accggcatta gcacgtggtg aattacaatg tattggtgct actacattag
     6781 atgaatatcg caaaaatatt gaaaaagacg cggctttaga acgtcgtttc caacctgtac
     6841 aagttgatga accttcagta gtagatacag ttgctatttt aaaaggatta agagatcgtt
     6901 acgaagcaca ccatcgtatt aatatttcag acgaagctat tgaagcagct gttaaattaa
     6961 gtaacagata cgtttcagat cgtttcttac cagataaagc aattgattta attgatgaag
     7021 caagttctaa agtaagactt aagagtcata cgacacctaa taatttaaaa gaaattgaac
     7081 aagaaattga aaaagttaaa aatgaaaaag atgccgcagt acatgctcaa gagtttgaaa
     7141 atgctgctaa cctgcgtgat aaacaaacaa aacttgaaaa gcaatatgaa gaagctaaaa
     7201 atgaatggaa gaatgcacaa aatggcatgt caacttcatt gtcagaagaa gatattgctg
     7261 aagttattgc aggatggaca ggtatcccat taactaaaat caatgaaaca gaatctgaaa
     7321 aacttcttag tctagaagat acattacatg agagagttat tgggcaaaaa gatgctgtta
     7381 attcaatcag taaagcggtt agacgtgccc gtgcagggtt aaaagatcct aaacgaccaa
     7441 ttggtagctt tatcttcctt ggaccaactg gtgttggtaa aactgaatta gctagagctt
     7501 tagctgaatc aatgtttggc gatgatgatg cgatgatccg tgtagacatg agtgaattta
     7561 tggaaaaaca cgcagtgagc cgattagttg gtgctcctcc aggatatgtt ggtcatgatg
     7621 atggtggaca attaactgaa aaagttagac gtaaaccata ttctgtaatt ttatttgatg
     7681 aaattgaaaa agctcatcca gatgtattta atattctatt acaagtttta gatgatggac
     7741 atttgacaga tacaaaagga cgtacagttg atttcagaaa tacaattatc ataatgacat
     7801 caaacgttgg ggcacaagaa ttacaagatc aacgatttgc tggattcggt ggttcaagtg
     7861 atggacaaga ttatgaaaca attcgaaaaa cgatgttaaa agaattaaaa aattcattcc
     7921 gtccagaatt tttaaaccgt gtagatgata tcattgtatt ccataaacta acaaaagaag
     7981 aattaaaaga aattgtaaca atgatggtta ataaattaac aaatcgatta tctgaacaaa
     8041 acataaatat tattgttact gataaagcga aagacaaaat cgcagaagaa ggatatgatc
     8101 cagaatatgg tgcaagacca ttaattagag cgatacaaaa aactatcgaa gataatttaa
     8161 gtgaattaat attagatggt aatcaaattg aaggtaagaa agttacagta gatcatgatg
     8221 gtaaagagtt taaatatgac attgctgaac aaacttcaga aactaaaaca ccatcgcaag
     8281 cataattata aaacagtcca aaacaaatta aagttttggg ctgttttttt agtagcattg
     8341 aactatagaa attcgtgaaa gtatccatca acgaaacaat ctaataaaac aatcatcaaa
     8401 ggatagttaa gaattatatg taacaagtta atgagcctac agcgatagca taaaggtatg
     8461 aatttttata aaggtttttt gtttgaagat actagcaact tacgtcaaaa taaaataggt
     8521 ctatataata ttgtgataaa tctagagaaa agagtttact aagaaattat taagatttta
     8581 tctttgaaag ataccgacta tcaacatgat gtaagtttat tttataatat tcataaaaaa
     8641 taaatctggt aaaacagttt gcgttagtag tcatgttaaa atacaaacaa atgtaactca
     8701 catttaattt gtcataatgg gaatgtgcgt ttaaaataga tttgttcaaa ggaaagtgga
     8761 ggtgcaattt tggccaagaa aaaagtgatt tttgaatgta tggcttgtgg ttatcaatct
     8821 cctaaatgga tggggaaatg tcctaattgt ggcgcttgga atcaaatgga ggaaattgtt
     8881 gaaaaagcag ccaatcctaa acatggagtt aaaaccaagg aattagcagg taaagtacaa
     8941 aaattaaata gtattaaaca tgaaacaacg ccgagagtgt taacagattc agcagaattc
     9001 aaccgtgtat taggtggagg tattgtgagc ggatcgttag tacttattgg tggggatcca
     9061 ggtattggta agtcaacgtt acttttacaa atttgtgcat cgttatctca aaagaaaaaa
     9121 gtactatata ttactggaga agaatcgctt agtcagacta aattacgtgc agagcgatta
     9181 gatgaagatt caagtgaatt gcaagtatta gctgaaacag atcttgaagt tatttatcaa
     9241 acagtaaaag aagaacaacc tgatttatta gtagtggatt cgattcaaac aatatatcat
     9301 cctgaaatca gctctgcgcc aggttctgtt tcacaagttc gtgaaagtac acaaagttta
     9361 atgaatattg ctaaacaaat gaacattgca acttttatag tgggtcatgt aacgaaagaa
     9421 ggtcaaattg ctggcccaag attgctagaa cacatggttg atactgtgct ttattttgaa
     9481 ggcgatgaac accacgcata tcgaattttg cgagctgtta aaaaccgttt tggttcaacg
     9541 aatgaaatgg gaatcttcga aatgaagcaa agtggattaa aaggtgtaaa taatccatct
     9601 gaaatgtttt tagaagaacg ttcaacaaat gttccaggtt caacaattgt tgcaaccatg
     9661 gagggaacca gaccactttt aatagaagtt caagcgctgg taactccaac gacttttaac
     9721 aatccgagac gaatggcaac agggattgat cataatcgat taagtttgtt gatggctgtt
     9781 ttggaaaaga aagaaaatta tctattacaa caacaagatg cttatatcaa agtagctggc
     9841 ggtgtaaagt taacggagcc agcagttgat ttaagtgtaa ttgtagcaac tgcatctagc
     9901 tttaaagata aagctgtcga cggattagat tgctatattg gagaagttgg tttaacgggt
     9961 gaggtacgtc gtgtatctcg gatagaacaa cgcgtgcaag aggctgcaaa actaggtttc
    10021 aaacgtgtaa ttattcctaa aaataatata ggcggatgga catatcctga aggtatacaa
    10081 gtaataggtg taactactgt acatgaagca ttgtcatttg ctcttcattc ataaaacatc
    10141 aagaaaggag gacattgtgt gaatatcgtt aaactaatgg ttattattat ttacttaatt
    10201 attgggagcg cattaggaat aattattatt cctgaaattg caaatgatct tggattacaa
    10261 aactccagct ttttaaaaaa tcactatgta gatggcatta tcggtagtat ttttatgttc
    10321 ttaatttttg gtgtatttat tagacgagtt actaacgcta taaaaggttt agaacatttt
    10381 attatgcgta gaagtgctgt tgaaatacta ttcgcaacaa taggtttaat aatcggatta
    10441 cttatttctg ttatggtgtc gtttatatta gaatcaattg gtaactctat ttttaatcat
    10501 ttcattcctg tcataattac gatattacta tgttatttcg gtttccaatt tggccttaaa
    10561 aaacgagatg aaatgttaat gtttttacct gagaatatag cgcgttccat gtcacaacat
    10621 actaaaagtg ctacgccaaa aattatcgac acaagcgcaa ttattgatgg tcgtatttta
    10681 gaagtcattc gttgcggttt tatcgatggc aatattttaa ttccgcaagg tgttattaat
    10741 gaattacaaa ttgttgcaga ttcaaatgac agtgttaaac gtgaaaaggg taaaagaggc
    10801 ttagatattt taaatgaatt gtatgattta gattatccta caaaggttat acatccaact
    10861 aaaacacata gtgatattga tacaatgcta ttaaagctag ctaaacaata tcatgcaagt
    10921 attattacga cagatttcaa cctaaataaa gtttgtcatg tacatggtat caaagcatta
    10981 aatgttaatg atttatcaga agcaatcaaa cctaatgtac atcaaggtga tcaactgcat
    11041 attttactga caaaaatggg taaagagcct ggtcaggcag taggatatct agatgatggt
    11101 acgatggtag ttgttgataa tgctaaaaat cttattggca gtcatgtcaa tttagaagta
    11161 gtcagcttat tgcaaacatc ttcaggaaga attgtttttg ctaaaaaaat cgaagataca
    11221 gtatcattat aaaaactgta gttgacgaaa acaaaataga tattaaaagg tatatgaaat
    11281 ggcgaagttt gtaatttgaa gtataactat aaataaatgc aaaacatatc agttatcaaa
    11341 aaatacaaat agtgctaata tatcattgaa acaagttcat taagtgttaa attttagata
    11401 ttaataaagt tattcttata gcaatcaaga catacaaaat tagaatcaat tttaacgtat
    11461 ttgaatagtt aatttgaagt ttaattttac agtacataat attcattttt aagtcgttga
    11521 aatgcttatg tagtgcagtc ttgattctta gggatagctt ttttaaagtg ttgaaaaaac
    11581 aactgctttc tatttaaaat ttaagcatat tacccagtga attatgttat gattaaacaa
    11641 tgaaattatt ttaaggtcat gttaaaaagc attgtttcgt tttaacaata agacgagtta
    11701 gacatttgtt atgacggtcg aagatagcaa atgaataatt tatatgaact aacttgaaaa
    11761 tctgatattt aatttaggag tgaaaaaaat gagcgatcgt ataagagtaa gatatgcacc
    11821 aagtccaact ggttatcttc atattggtaa tgcaagaaca gcattattca attacttgta
    11881 tgctaaacat tacaacggag attttgtgat tcgaattgaa gatactgata aaaaacgtaa
    11941 tttagaagat ggagaaacat cacaatttga taatcttaaa tggttaggat tagattggga
    12001 tgagtctgta gataaagaca atggctacgg accatatcgt caatctgaac gtcaacatat
    12061 ctaccaacca ttaatagatc agttactagc agaagataaa gcatataaat gctatatgac
    12121 agaagaagaa ttagaagctg aacgtgaagc gcaaatcgct cgtggtgaaa tgcctcgcta
    12181 tggtggtcaa catgcgcatt tgactgaaga acaacgtcaa caatttgaag cagaaggacg
    12241 ccaaccatca attcgtttcc gagtacctca aaaccaaacg tattcatttg atgatatggt
    12301 aaaaggaaat atttcatttg attcaaatgg tattggtgac tgggttatcg taaaaaaaga
    12361 tggcattcca acgtacaatt ttgcagtagc tatagatgat cattacatgc aaatttcaga
    12421 tgtaattcgt ggtgatgatc atatttcaaa cacgcctaaa caaattatga tttatgaagc
    12481 atttggctgg gagccacctc gttttggtca tatgtcatta attgttaatg aagaacgtaa
    12541 aaagttaagt aaacgtgatg ggcaaatttt acaatttatt gagcaatatc gtgacttagg
    12601 ttatttacct gaagcgttat ttaattttat tgcgttatta ggttggtctc ctgaaggtga
    12661 agaagaaatc ttttctaaag aagaatttat caaaatcttt gatgaaaagc gtttgtcaaa
    12721 atcaccagca tttttcgata agcaaaaatt agcatgggtt aataaccaat atatgaaaca
    12781 aaaagatact gaaacagtat tccaattagc attacctcat ttaattaaag caaatttgat
    12841 tcctgaggtg ccgtcagaag aggatttatc ttggggacgc aaattaattg cgctttatca
    12901 aaaagaaatg agttatgccg gtgaaattgt acctttatca gaaatgttct ttaaagaaat
    12961 gccagctctt ggtgaagaag aacaacaagt gattaatgga gagcaagtac cagagttaat
    13021 gacgcactta ttcagtaaat tagaagcact tgaaccattt gaagcggctg aaattaaaaa
    13081 gacaattaaa gaagttcaaa aagaaacagg aataaaaggc aagcaattat ttatgcctat
    13141 tcgtgttgct gtaacaggcc aaatgcatgg tcctgaatta ccaaatacaa ttgaagtact
    13201 tggtaaagaa aaagtgctaa accgtttaaa acaatataag taatgaaata gacaagatca
    13261 aggtagtata tacttgaatt ttataacgta accacatatg ataaagttgt attaacaaat
    13321 tacaacaata tgaataaagt attttatata aaacgaagga ttagtaatta aatttatacg
    13381 atgcagagag tgtacggttg ctgtgagtac aacgtagaaa ttaatgaatg caccttcgta
    13441 aaatgaatta aatatataat gagagtgatg agcattaagt tgacttagtc tccttgataa
    13501 tttggaagcg cccgcaatat tattaatgtt attcgctaaa ttcagagtgg aaccgtgcgg
    13561 aagcgcctct aacaatacaa tttgtatgtt agtggtgctt ttttgatatt taatttcgca
    13621 ggtacttcaa ttatgtattt acgtagttca atcattgagg aggaaatgat cttgttaaaa
    13681 agaatgagag acgatataaa aatggtattt gagcaggatc cagcggcacg ttcaacatta
    13741 gaagtcatta caacgtatgc aggtttacat gcagtttgga gtcatttgat tgcacataag
    13801 ttatacaacc aaaaaaaata tgttgcagca cgcgcgatat ctcaaatttc aagatttttc
    13861 acaggtatag aaatccatcc aggtgctaaa attggaaagc gtctatttat agatcatggt
    13921 atgggcgttg taataggaga aacatgtaca attggtgata atgtgacaat ctatcaaggc
    13981 gtgacacttg gtgggacagg gaaagaaaga gggaaaagac acccagatat aggagacaat
    14041 gttttaatag cagccggtgc gaaagtttta ggaaatatta aaataaattc aaatgtaaat
    14101 attggtgcaa attcagttgt tttacaatca gttccaagtt attcaacggt tgttggtata
    14161 ccaggacata ttgttaagca agatggtgtt cgagttggaa aaacatttga tcatcgccat
    14221 ctacctgatc caatttatga acaaattaag catttagaac gacaacttga aaagactagg
    14281 aatggagaga ttcaagatga ttacattata taatacgctt acacgtcaaa aagaagtgtt
    14341 caagcctata gaaccaggga aagtaaaaat gtatgtatgt ggtcctactg tatataacta
    14401 cattcatatt ggtaacgcaa gaccagcaat taattatgac gtagtgagac gttactttga
    14461 ataccaagga tataatgtag aatatgtatc aaattttaca gacgtagatg ataaattaat
    14521 taaacgttct caagaattaa atcagtctgt tcccgaaatt gcagaaaaat atatcgctgc
    14581 ttttcatgaa gatgttggtg cgttaaatgt tagaaaagcg acttcaaatc caagggtaat
    14641 ggaccatatg gatgacatta ttcaatttat taaagatttg gtggatcaag gttatgcata
    14701 tgaaagtggt ggcgatgttt actttagaac acgtaaattt gaaggttatg gtaaattaag
    14761 tcatcaatcc atagatgact taaaagtggg tgctcgtata gatgcaggag agcataaaga
    14821 agatgcactt gattttacat tgtggaaaaa agcgaagcct ggcgagatta gttggaatag
    14881 cccatttggt gaaggtagac caggatggca tatagaatgt tctgtaatgg catttcatga
    14941 gctaggacct acaattgata tacatgcggg tggttcagat ttacaatttc cacatcatga
    15001 aaatgaaata gcacaatcag aagcacataa tcatgcgcca tttgctaatt attggatgca
    15061 taatggtttc attaatattg ataatgaaaa aatgagtaaa tcactaggca actttatttt
    15121 agttcacgat attattaaag aagttgatcc agatgtacta agattcttta tgattagcgt
    15181 acattataga agcccaatta actataatct agaattggta gaatcagcac gtagtggact
    15241 agagcgtatt cgcaatagtt atcaattaat tgaagagcgc gcacaaattg ctactaatat
    15301 tgaaaatcaa cagacatata ttgatcaaat tgatgcgatt ttaaatcgtt ttgaaacagt
    15361 tatgaatgat gattttaata cagctaatgc aattacagct tggtatgatt tagcaaaact
    15421 tgcgaataaa tatgtactag agaacacaac atcaacagaa gtaattgata aatttaaagc
    15481 agtttatcaa attttcagcg atgttttagg tgtaccgtta aaatctaaaa atgcagatga
    15541 attattggat gaagatgttg aaaaattaat cgaagagcgt aatgaagcaa ggaaaaacaa
    15601 agattttgca cgagcagatg agattcgaga catgctgaaa tcacaaaaca ttatattaga
    15661 agacacacct caaggggtta gatttaaacg tggataatca acaagataat cacattaaat
    15721 tattgaatcc attgacctta gcatatatgg gagacgcagt cttagatcaa tatgtacgta
    15781 cctatatcgt tttaaagctt aaaagtaagc ctaataaact acatcaaatg tctaaaaaat
    15841 atgtatctgc caaaagtcag gcgcaaacgt tagaatattt aatggagcaa gaatggttta
    15901 cagacgaaga aatggatatt ttgaagcgag ggcgtaacgc gaaaagtcat actaaagcta
    15961 aaaacactga tgttcaaaca tatcgtaaaa gttcagcgat agaagcagtg ataggttttc
    16021 tttatttaga aaaaagagaa gaacgattag aggcattatt aaataaaata ataacaatag
    16081 taaacgaaag gtagtgacga tgtggaagat acggttattg ttggtaggca tgctgttaga
    16141 gaagcgatta ttactgggca tccgataaat aagatattga ttcaagaagg tattaaaaag
    16201 caacaaatta atgaaatttt aaaaaatgca aaagatcaaa aaattattgt tcaaactgta
    16261 ccaaaatcta aattagattt tttagcaaat gcaccacatc agggtgttgc agcgcttatt
    16321 gcaccatatg aatatgctga cttcgatcaa tttttaaaac agcaaaaaga aaaagaaggt
    16381 ttatcgacag tacttatatt agacggctta gaagacccgc ataacttggg atcaatttta
    16441 agaacagccg atgcaacggg agttgatggt gttattattc ctaaacgtcg ttcagttaca
    16501 ctaacgcaaa cagttgcaaa agcctcaaca ggtgcaattg aacatgtacc agttattcga
    16561 gtgacaaatt tagctaaaac tatcgatgaa ctaaaagata atggcttttg ggtagctggc
    16621 actgaagcta ataatgcaac agattataga aatctagaag cggacatgtc attggctatt
    16681 gtaattggta gcgaaggaca gggtatgagt cgcctagtaa gtgataaatg cgatttttat
    16741 attaagattc caatggttgg acatgtaaac agtttgaatg cttcggttgc agcaagttta
    16801 atgatgtacg aagtatttcg aaaaagacat gatgttggag aaatataatg aaagaacgtt
    16861 acttaatcat tgatggatac aatatgatag gacaatcacc aacgctaagc gccattgcaa
    16921 aagagaattt agaagaagct agaatgcaat taatagatgc aattgcaaat tataatgcag
    16981 ttatttcaga tgaaattatt tgtgttttcg atgcttatga ccaatcgggt gttgaaagag
    17041 aatacatgta tcatggcgtt aaaacgattt ttaccaagga aaaagaaaca gctgatagtt
    17101 tcatagaacg ttatgtttat gaactttatg acaagcatac taagcatatt gcagttgtaa
    17161 caagtgatat gagtgagcaa catgctatct ttggatcagg tgcatataga atatcatctc
    17221 gcgaaatgtg gagagattta aaagaaaatg aaattgatgt gagtaaatca ttagatgata
    17281 taagtgaaaa caagccaaga actcgaattc cgttatcttc tgaaatcctt gcagaatttg
    17341 aaaaaatacg aagaggacat cataagaaat gacatttccg tcatcttgaa attttgaatg
    17401 taacaatatt aaactaacct taaattttag atagaagggg ttagtttaat acttgaaata
    17461 tgatttgaca actcaagaca gtacaatcaa acgtaacaat tcaataaatg ataaagactt
    17521 cgaaaagtta gtaatggatc tacaaccatt aattattcga cgcatcaaaa catttggatt
    17581 taatcattat gatttagaag acttatatca agaaatactt atacggatgt ataggtcggt
    17641 ccaaacattt gattttagtg gagagcagcc tttcacaaat tatgttcaat gtttaattac
    17701 gtctgtaaag tatgattatt tgagaaaata tttagctaca aataaaagaa tggataattt
    17761 gattaatgaa tatagagtta cgtatccatg tgcaataaag cgttttgatg ttgaaaacaa
    17821 ttatttgaat aaattagcaa ttaaagagtt gatttgtcag tttaagtatt tgagtgcatt
    17881 tgaaaaagat gtcatgtatt taatgtgtga acaatataag ccgagagaaa ttgctcaatt
    17941 gatgcatgta aaagagaaag tgatttataa tgccatacaa cgatgtaaaa ataaaataaa
    18001 acgttatttc aaaatgattt gaaaagcgcc ttaggacgtg aattgaatta taacgtgtta
    18061 cttactgatg gtttgacatt tgttataaat tttatgtata gtatactggt attataatga
    18121 ataaaggtga attattgtga gaaaaatacc tttaaattgt gaagcttgtg gcaatagaaa
    18181 ttataatgtt cctaagcaag aaggctcggc aacaagatta accttaaaga aatattgtcc
    18241 aaaatgtaac gcgcacacaa ttcataaaga atcgaaataa atacattcga aataatactt
    18301 tgataatatg ttcaaaggat ttggaggttg agcagatggc taaaaaagaa agtttcttta
    18361 aaggcgttaa gtctgaaatg gaaaaaacaa gttggccgac gaaagaagag ctatttaaat
    18421 atactgtaat tgtagtttct actgttatat tcttcttagt ctttttctat gccttagatt
    18481 taggaattac agcattgaaa aatttattat ttggttagag gagtgaagac atgtctgaag
    18541 aagttggcgc aaagcgttgg tatgcagtgc atacatattc tggatatgaa aataaagtta
    18601 aaaagaattt agaaaaaaga gtagaatcta tgaatatgac tgaacaaatc tttagagtag
    18661 tcataccgga agaagaagaa actcaagtaa aagatggcaa agctaaaacg actgttaaaa
    18721 aaacattccc tggatatgtt ttagtggaat taatcatgac agatgaatca tggtatgtgg
    18781 taagaaatac accaggcgtt actggttttg taggttctgc aggtgcaggg tctaagccaa
    18841 atccattgtt accagaagaa gttcgcttca tcttaaaaca aatgggtctt aaagaaaaga
    18901 ctatcgatgt tgaactcgaa gttggcgagc aagttcgtat taaatcaggt ccatttgcga
    18961 atcaagttgg tgaagttcaa gaaattgaaa cagataagtt taagctaaca gtattagtag
    19021 atatgtttgg ccgagaaaca ccagtagaag ttgaattcga tcaaatagaa aagctttaat
    19081 taacaattaa agttattaaa ctaaccaaaa gataaaaaag agtattgatt ttttaattag
    19141 aaaagtgtta aaattatgtg gtcgcgcttt tagagcgccc atttcgtcac gaaatgttaa
    19201 gagtgggagg gcaaaactga gccctgtgac cacatcacga tatcaaggag gtgcacatcg
    19261 tggctaaaaa agtagataaa gttgttaaat tacaaattcc tgcaggtaaa gcgaatccag
    19321 caccaccagt tggtccagca ttaggtcaag caggtgtgaa catcatggga ttctgtaaag
    19381 agttcaatgc acgtactcaa gatcaagcag gtttaattat tccggtagaa atcagtgttt
    19441 atgaagatcg ttcatttaca tttattacaa aaactccacc ggctccagta ttacttaaaa
    19501 aagcagctgg tattgaaaaa ggttcaggcg aaccaaacaa aactaaagtt gctacagtaa
    19561 ctaaagatca agtacgcgaa attgctaaca gcaaaatgca agacttaaac gctgctgacg
    19621 aagaagcagc tatgcgtatt atcgaaggta ctgcacgtag tatgggtatc gttgtagaat
    19681 aattttacga atattaaatt tgattacatg atttaaacga tgaagcagat aacagagata
    19741 ataatgatga attataaata taatctgaat gactagatta atgattgatt tattcataag
    19801 attaattctt ctgttgtctg ctcttaactt gcatatagca agtaatgtgg gaggaaattc
    19861 cgctaaaacc actaaaggag gaactataaa tggctaaaaa aggtaaaaag tatcaagaag
    19921 cagctagtaa agttgaccgt actcagcact acagtgttga agaagcaatt aaattagcta
    19981 aagaaacaag cattgctaac tttgacgctt ctgttgaagt tgcattccgt ttaggaattg
    20041 atacacgtaa aaatgaccaa caaatccgtg gtgcagttgt attaccaaac ggaactggta
    20101 aatcacaaag tgtattagta ttcgctaaag gtgacaaaat tgctgaagct gaagcagcag
    20161 gtgctgacta tgtaggtgaa gcagaatacg ttcaaaaaat ccaacaaggt tggttcgact
    20221 tcgatgtagt agttgctaca ccagacatga tgggtgaagt tggtaaatta ggtcgtgtat
    20281 taggaccaaa aggtttaatg ccaaacccta aaactggaac tgtaacaatg gatgttaaaa
    20341 aagctgttga agaaatcaaa gctggtaaag tagaatatcg tgctgaaaaa gctggtatcg
    20401 tacatgcatc aattggtaaa gtttcattta ctgatgaaca attaattgaa aacttcaata
    20461 ctttacaaga tgtattagct aaagctaaac catcatctgc taaaggtaca tacttcaaat
    20521 ctgttgctgt aactacaaca atgggtcctg gagttaaaat tgatactgca agtttcaaat
    20581 aataaatgat ataaacaatt acaggctgaa agaaatatct ttcagtctgt aaaaatatat
    20641 tgacaataag taatttccaa gttatattac ttattgtgat tattttacct aagacagtag
    20701 gagttattta taacttaaaa tttatcctgc cgaggctaaa attgacttga acgtgatgat
    20761 ctatgatctt tcaagcactt tttgccgtgg gtagaaagtg ctttttttat taattttaaa
    20821 aaaagcacca aaaatttaaa tggaggtgtc tgaatgtctg ctatcattga agctaaaaaa
    20881 caactagttg atgaaattgc tgaggtacta tcaaattcag tttcaacagt aatcgttgac
    20941 tatcgtggat taacagtagc tgaagttact gacttacgtt cacaattacg tgaagctggt
    21001 gttgagtata aagtatacaa aaacactatg gtacgtcgtg cagctgaaaa agctggtatc
    21061 gaaggcttag atgaattctt aacaggtcct actgctattg caacttcaag tgaagatgct
    21121 gtagctgcag cgaaagtaat ttctggattt gctaaagatc atgaagcatt agaaattaaa
    21181 tcaggcgtta tggaaggcaa tgttattaca gcagaagaag ttaaaactgt tggttcatta
    21241 ccttcacacg atggtcttgt atctatgctt ttatcagtat tacaagctcc tgtacgcaac
    21301 ttcgcttatg cggttaaagc tattggagaa caaaaagaag aaaacgctga ataattttta
    21361 gcgtaaaaaa attaaaaata atggaggaat tataaaatgg ctaatcatga acaaatcatt
    21421 gaagcgatta aagaaatgtc agtattagaa ttaaacgact tagtaaaagc aattgaagaa
    21481 gaatttggtg taactgcagc tgctccagta gcagtagcag gtgcagctgg tggcgctgac
    21541 gctgcagcag aaaaaactga atttgacgtt gagttaactt cagctggttc atctaaaatc
    21601 aaagttgtta aagctgttaa agaagcaact ggtttaggat taaaagatgc taaagaatta
    21661 gtagacggag ctcctaaagt aatcaaagaa gctttaccta aagaagaagc tgaaaaactt
    21721 aaagaacaat tagaagaagt tggagctact gtagaattaa aataattcaa gtatcttaaa
    21781 cttaataatc aaagttttat agcaagtatt gctataatat aatgattctt tgagaag
//
LOCUS       DAPDIM010000047        21662 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000047 DAPDIM010000000
VERSION     DAPDIM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21662
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.047"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..83
                     /locus_tag="RFE25_001912"
     CDS             <1..83
                     /locus_tag="RFE25_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDU2816962.1"
                     /translation="LYKKNRRSLQIYGFSPCHEISIMLAS"
     gene            complement(318..2501)
                     /gene="cadA"
                     /locus_tag="RFE25_001913"
     CDS             complement(318..2501)
                     /gene="cadA"
                     /locus_tag="RFE25_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase CadA"
                     /protein_id="HDU2816963.1"
                     /translation="MSEQKVKLMEEEMNVYRVQGFTCANCAGKFEKNVKKIPGVQDAK
                     VNFGASKIDVYGNASVEELEKAGAFENLKVSPEKLANQTIQRVKDDTKAHKEEKTPFY
                     KKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVGSIVIGGYSLFKVGFQNLIRFDF
                     DMKTLMTVAVIGAAIIGEWAEASIVVVLFAISEALERFSMDRARQSIRSLMDIAPKEA
                     LVMRNGQEIMIHVDDIAVGDIMIVKPGEKIAMDGIIINGVSAVNQAAITGESVPVAKT
                     VDDEVFAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAPAQAFVDKFAKYYT
                     PIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAK
                     KGVLIKGGVYLEELGAIKAIAFDKTGTLTKGVPVVTDFEVLNDQVEEKELFSIITALE
                     YRSQHPLASAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGTTYYIGSPKLFKEL
                     NVSDFSLGFENNVKILQNQGKTAMIIGTEKTILGVIAVADEVRETSKNVIQKLHQLGI
                     KQTIMLTGDNQGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDNVAMIGDGVND
                     APALAASTVGIAMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFA
                     IGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMRVKDK"
     gene            complement(2494..2862)
                     /gene="cadC"
                     /locus_tag="RFE25_001914"
     CDS             complement(2494..2862)
                     /gene="cadC"
                     /locus_tag="RFE25_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory
                     transcriptional repressor CadC"
                     /protein_id="HDU2816964.1"
                     /translation="MKKKDTCEIFCYDEEKVNRIQGDLQTVDISGVSQILKAIADENR
                     AKITYALCQDEELCVCDIANILGVTIANASHHLRTLYKQGVVNFRKEGKLALYSLGDE
                     HIRQIMMIALAHKKEVKVNV"
     gene            complement(3425..4270)
                     /gene="blaZ"
                     /locus_tag="RFE25_001915"
                     /pseudo
     CDS             complement(3425..4270)
                     /gene="blaZ"
                     /locus_tag="RFE25_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
     gene            4377..6134
                     /gene="blaR1"
                     /locus_tag="RFE25_001916"
     CDS             4377..6134
                     /gene="blaR1"
                     /locus_tag="RFE25_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="HDU2816965.1"
                     /translation="MAKLLIMSIVSFCFIFLLLLFFRYILKRYFNYMLNYKVWYLTLL
                     AGLIPFIPIKFSLFKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFATDIHKFNWDSI
                     DNICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIV
                     IRKAETIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFN
                     IFSIIMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLNVPFFN
                     KNILSHSFNGKKSLLKRRLINIKEANLKKQSKLILIFICIFTFLLMVIQSQFLMGQSI
                     TDYNYKKPLHNDYQILDKSKIFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPNSTYK
                     IYLAMFGLDRHIINDENSRMSWNHKHYPFDAWNKEQDLNTAMQNSVNWYFERISDQIP
                     KNYTATQLKQLNYGNKNLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQ
                     LSSSLLIKKNEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGKPSGK
                     NAELISEKILKEMGVLNGQ"
     gene            6124..6504
                     /gene="blaI"
                     /locus_tag="RFE25_001917"
     CDS             6124..6504
                     /gene="blaI"
                     /locus_tag="RFE25_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillinase repressor BlaI"
                     /protein_id="HDU2816966.1"
                     /translation="MANKQVEISMAEWDVMNIIWDKKSVSANEIVVEIQKYKEVSDKT
                     IRTLITRLYKKEIIKRYKSENIYFYSSNIKEDDIKMKTAKTFLNKLYGGDMKSLVLNF
                     AKNEELNNKEIEELRDILNDISKK"
     gene            6768..7346
                     /locus_tag="RFE25_001918"
     CDS             6768..7346
                     /locus_tag="RFE25_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDU2816967.1"
                     /translation="MKIGYARVSTGLQNLNLQEDQLNQYGCEKIFSDHISGSKSKRPG
                     LDKAIEFARAGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSST
                     GQLLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLKLLKTLYDNG
                     TPIKTIAEQWKVSRTTIYRYLNRLNNQENKDK"
     gene            7472..8080
                     /locus_tag="RFE25_001919"
     CDS             7472..8080
                     /locus_tag="RFE25_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDU2816968.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRP
                     VFQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGN
                     PLLDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQ
                     KRVIYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
     gene            8326..8664
                     /locus_tag="RFE25_001920"
     CDS             8326..8664
                     /locus_tag="RFE25_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816969.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRK
                     MFIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYY
                     TTNKKYTSKG"
     gene            8669..8854
                     /locus_tag="RFE25_001921"
     CDS             8669..8854
                     /locus_tag="RFE25_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2816970.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTL
                     AFKLARLFDTTVDELFS"
     gene            complement(8987..9553)
                     /gene="qacR"
                     /locus_tag="RFE25_001922"
     CDS             complement(8987..9553)
                     /gene="qacR"
                     /locus_tag="RFE25_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001807342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug-binding transcriptional regulator
                     QacR"
                     /protein_id="HDU2816971.1"
                     /translation="MNLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFK
                     TKENLFLEILNIEESKWQEQWKKEQIKCKTNREKFYLYNELSLTTEYYYPLQNAIIEF
                     YTEYYKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWCINDVNAVSKIAANAVNGIV
                     TFTHEQNINERIKLMNKFSQIFLNGLSK"
     gene            9731..11275
                     /locus_tag="RFE25_001923"
     CDS             9731..11275
                     /locus_tag="RFE25_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /protein_id="HDU2816972.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPE
                     LVRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIF
                     FAESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFG
                     PIIGGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIA
                     GMIGLVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSF
                     SAGTIAAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLA
                     ARFGPKIVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGMASLAVASALIML
                     ETPTSKAGNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHV
                     AEESVVGAVEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSL
                     DITKQK"
     gene            11480..12040
                     /locus_tag="RFE25_001924"
     CDS             11480..12040
                     /locus_tag="RFE25_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816973.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLC
                     LTLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRV
                     IKKYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMI
                     MIFDLIIGLLLNFQIFLKNKKYDDFL"
     gene            12116..12238
                     /locus_tag="RFE25_001925"
     CDS             12116..12238
                     /locus_tag="RFE25_001925"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDU2816974.1"
                     /translation="MAPYTNKGYAVKELCSYLQINMDDVYTIGDRKLIYLCLIP"
     gene            complement(12356..13126)
                     /locus_tag="RFE25_001926"
     CDS             complement(12356..13126)
                     /locus_tag="RFE25_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDU2816975.1"
                     /translation="MKTIKMVADELNVTKQTIVNNAKNLNISFKKENGINYINDNDCL
                     KIIEKITKKERTMQNKESIKKERFNENTAEFEKHIYNNSNGFESLKTKVNELEKQIEI
                     FETRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLENQLEEER
                     QLNYSFDTATNDRQSINPQEATFTEEYQNSNQQQKKIQPIEAELNHKGITKAKKDDSS
                     NEDVLKRDDKLSEEIESGPEDREVETPKKGFWSRLFGS"
     gene            13570..14514
                     /locus_tag="RFE25_001927"
     CDS             13570..14514
                     /locus_tag="RFE25_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDU2816976.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALL
                     KDRFELSIQNEWVDRNNNIYFIFSNKHLCEYLGYGEQKIIKLKKELVNFNLLTQERVG
                     LNKPNRLYLLKPNYDIEASLTKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTELN
                     NTNYIENEDNDTYDMNDIISNTLINNNHHSNHTNHQKTEFNNDALKFQVLEELPQQLQ
                     DYLSKFEIREIRIIKSVLLKGKKSFNTSHDTYYRLEDVEFEIVSVLKRFKAMLLQKNE
                     TVEAMQGYLMQSIKAELEETHALYMRRKNMKQYNIFNQ"
     gene            14507..14832
                     /locus_tag="RFE25_001928"
                     /pseudo
     CDS             14507..14832
                     /locus_tag="RFE25_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
     gene            14837..14983
                     /locus_tag="RFE25_001929"
     CDS             14837..14983
                     /locus_tag="RFE25_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816977.1"
                     /translation="MNTKILTGMTGSSLERKINNFINDNQIEVIDIKFSSSVFYFGVM
                     IIYK"
     gene            15563..15751
                     /locus_tag="RFE25_001930"
     CDS             15563..15751
                     /locus_tag="RFE25_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816978.1"
                     /translation="MNKDTMLDKGYVIATILNVFFLLGLIFISHLENLYILIPYVILM
                     GINAIYLVVKVMNFKKNN"
     gene            16135..16751
                     /gene="cadD"
                     /locus_tag="RFE25_001931"
                     /pseudo
     CDS             16135..16751
                     /gene="cadD"
                     /locus_tag="RFE25_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
     gene            16770..17117
                     /locus_tag="RFE25_001932"
     CDS             16770..17117
                     /locus_tag="RFE25_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2816979.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKK
                     LKIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDD
                     GIREFFSKNHEGF"
     gene            complement(17483..17584)
                     /locus_tag="RFE25_001933"
                     /pseudo
     CDS             complement(17483..17584)
                     /locus_tag="RFE25_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(18466..19377)
                     /locus_tag="RFE25_001934"
     CDS             complement(18466..19377)
                     /locus_tag="RFE25_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014533071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HDU2816980.1"
                     /translation="MSNFATEPNVSYADILEILKIKKAYNVKQCGNVLEFKPTDEGYL
                     KLHKTWFCKSKLCPVCNWRRAMKNSYQAQKVIEEVIKEKPKARWLFLTLSTKNAIDGD
                     TLEQSLKHLTKAFDRLSRYKKVKQNLVGFMRSTEVTVNKNDGSYNQHMHVLLCVENAY
                     FRKKENYITQEEWVNLWQKALQVDYRPVVNIKAIKPNQKGDKDIESAIKETSKYSVKS
                     SDFLTDDDEKNQEIVSDLEKGLYRKRMLSYGGLLKQKHKILNLDDAEDGNLINTSDED
                     KITDEEAKAHSITAIWNFEKQNYYLRH"
     gene            19414..20088
                     /locus_tag="RFE25_001935"
     CDS             19414..20088
                     /locus_tag="RFE25_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDU2816981.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVYH
                     STIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWNYLYRAIDADGHTLDI
                     SLRKKRDNHSAYTFIKRLIKQFGKPQMIITNQAPSTKVAMSKVIKDFKLTPNCHCNSK
                     YLNNLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRFLQIYGFSPCRVI
                     SIMLAS"
BASE COUNT         7581 a         3076 c         3257 g         7748 t
ORIGIN      
        1 ctctatataa aaagaaccgc aggtctcttc agatctacgg attttcgcca tgccacgaaa
       61 ttagcatcat gctagcaagt taagcgaaca ctgacatgat aaattagtgg ttagctatat
      121 ttttactttg caacagaacc agaattaata taacgagata tcaattcctg ttgctacata
      181 taccgcagct gctgtaagta tcgttgcgat catttttcca tctccaatat tttatatttt
      241 aggggtagga cttttcttca aattgaaaag ccccccttga attgcgcaca gcgtgacctt
      301 actattctgt tttctaccta tttatccttc actctcatca gtcgtaaact atttaatgct
      361 accaaaatag tagctcccat atcggaaaga atcgctatcc aaagggttaa ccatcccggg
      421 ataactaata gtaaggcaat tattttaatt ccgatagcaa aagtgatgtt agctttaatg
      481 atatttaaag tttttcgact gagtcttact gcaaatggaa gcttacttaa atcatctccc
      541 attaatgcaa tatcagctgt ttcaattgca gtatccgttc cagcaccgcc cattgcaatt
      601 ccaacagtag atgcagcaag tgctggagca tcattaacgc catcgccaat catagctaca
      661 ttatcatact ccgattgcat ttttttaata taatctaatt tatcctgtgg catcaattca
      721 gactgaatat cagaaacgcc tacatgtgta ccgattgcat ttgcagtacc ttgattatca
      781 cctgtcagca taattgtttg cttgatacct aactgatgaa gtttttgaat cacattttta
      841 cttgtttcac gaacctcatc tgcaacggca attacgccga gaattgtttt ttccgttcca
      901 ataatcatgg ctgtttttcc ttggttttgt aggattttca cattgttttc aaacccaagg
      961 ctaaaatcgg aaacatttaa ttccttgaaa agttttgggc ttccaatata gtaagtagtt
     1021 ccgtttacaa tcccttttat acctcgccca gtaatcgaag tgaattcttc cacttgtaca
     1081 ttagaataag ggatattatc ttgctctgcc tttttcatta ttgctgaagc aagtggatgt
     1141 tgtgaacgat attctaaagc tgtaatgata gagaatagct ctttttcttc cacttggtca
     1201 tttaatactt caaaatctgt taccactggt acaccttttg tcagtgttcc tgttttatca
     1261 aatgcgattg ccttaatggc tcctaattct tctagataga caccgccttt aatcaacaca
     1321 ccttttttag ctgcatttcc aattgccgag acaatcgaga ttggagtaga aataactaat
     1381 gcacacggac atccaactac aagtaccgct aatccttgat aaacccaagt atcccaactt
     1441 ccaccaaaga ataaaggtgg aacgactgca acgagcgccg caataaccat aatgatcggc
     1501 gtataatatt tcgcaaattt atctacgaat gcttgcgctg gagcgcgctc cccttgtgct
     1561 tcctcaacca gatgaataat cttggagata gttgtatcct ctacgtattt ggtgattttt
     1621 acttcaagta gtccctcttc gttaagcgta cctgcaaata cttcatcatc taccgttttg
     1681 gcaacaggga cagattctcc tgttatagca gcctggttga cagccgacac accatttata
     1741 atgatcccat ccatggcaat tttctcccct ggtttgacga tcataatatc acccacggca
     1801 atatcgtcca catggatcat tatttcctga ccattccgca taacaagtgc ttcttttggg
     1861 gcaatatcca tcaatgaacg aatggactgt cttgctctat ccatagaaaa acgttcaagt
     1921 gcttcactga ttgcaaagag aacgacaaca atggatgcct ctgcccattc accaatgatg
     1981 gcagctccaa taactgctac ggtcatcagg gttttcatgt cgaaatcaaa gcgtatcaaa
     2041 ttttgaaaac caactttaaa tagtgaatat ccgccaatta caatcgaacc tacaaataac
     2101 atggaagtta cgaggttatc ttctccattt acaaagtgag aaaggtaacc aaaagcaatt
     2161 agtagtgtgg caaacagcaa tgtactatgt tttttataaa atggtgtttt ctcttcttta
     2221 tgagccttag tgtcatcttt aaccctttgt atcgtttgat tcgctagttt ttcaggagat
     2281 acttttagat tctcaaaagc acctgctttt tcaagttctt caaccgatgc atttccatat
     2341 acatcaattt tagaagcgcc aaagtttact tttgcgtcct gaacgcctgg aatcttttta
     2401 acatttttct caaactttcc tgcacaattt gcacatgtaa atccttggac ccgatagacg
     2461 ttcatttctt cttccattag tttaaccttt tgttcagaca ttgaccttca cttctttctt
     2521 atgtgctagg gcgatcatca ttatctgcct gatatgttca tcacctaaag aatataaagc
     2581 tagttttcct tcttttctaa agttgaccac cccttgctta taaagcgtac gtaaatgatg
     2641 agatgcattt gctatcgtaa cacctaagat atttgctata tcacaaacac acaactcttc
     2701 atcctgacac agagcgtaag taatttttgc tctattttca tcggcaatag cctttaaaat
     2761 ttggctaaca ccagaaatat caactgtttg taaatcccct tgtattcgat taaccttttc
     2821 ttcgtcataa caaaaaattt cacaagtatc tttctttttc atattatcat cccatcttca
     2881 ttcaaatatt tatttgagtg tattataacc attttcgact catcatgcaa gcaaatattt
     2941 gaatgaaaat aaaagaagta agtagggcat aaaattctag tctcaaaaac gaacggtttt
     3001 gaccagggta tgacattaga aaataataca tttcaataag taaaataatt tattaaaaaa
     3061 tacacttgaa taagtgctat ttataaaggt taaaggcttg tagaactaaa taaattctat
     3121 aagtgtcact ttgcttgata tatgagaatt atttaacctt ataaatgaga aaaaagcaac
     3181 gcactttaaa taagatacgt tgctttttcg attgatgaac acctataatt aaactattca
     3241 tctattattt ataatttttt gtatatacaa tatttctagt ttgttaaaga gaattaagaa
     3301 aataaatctc gaaaataata gagggaaaat cagtttttga tatcaaaatt atacatgtca
     3361 acgataatac aaaatataat acaaaatata agatgttatc agtatttatt atgcatttag
     3421 aatattaaaa ttccttcatt acactcttgg cggtttcact tatcaactta tcatttggct
     3481 tatcactttt attgtcttta ttcgtaaaaa tgactaaaac aataggttca gattggccct
     3541 taggataaac aaaagcaaca tcatttctag aagcatatgt tattgcttga ccacttttat
     3601 cagcaacctt atagtctttt ggaacaccgt ctttaattaa agtatctccg cttttattat
     3661 ttaacattaa atcaagtaag aattttttgt tttctttgct taattttcca tttgcgataa
     3721 gtttatttaa agtcttaccg aaagcagcag gtgttgaagt atcttttttg ctctttggtg
     3781 aatagtaatt taattctatc tcatatctaa ctggatttgt tactttatct cctagttctt
     3841 ttagacgttg tttaactttt ttgattccac cgatttcttt tataatttta ttgtttgctg
     3901 tattatcact atatgtcatt gaagcctcaa taagtgcttt taaagtgata tcttttccta
     3961 catatttttc taaaatagga gaataagcaa ctatatcatc tttgttaata tgtacttttt
     4021 tatttaactt attataaggt acttattcta acaaaatagc actatttatc gcttttgaag
     4081 ttgaagcata ggcaaatctc ttatctgaat taaattttac ttccttacca cttttagtat
     4141 ctaaagcata aacaccaata tgagcattat attttttttc taaatcattt aactctttgg
     4201 catgtgaact gtttgaatta catgcactta aaactaaagc aattacaatt aaaaatatta
     4261 actttttcaa aataaaccct ccgatattac agttgtaatt tttataaatc aataatatta
     4321 caattgtaat atcggtgtca atagtttatt ataaatattt gaaagaaggt gttgaaatgg
     4381 ctaagttatt aataatgagc atagtaagct tttgttttat atttctattg ttattatttt
     4441 ttaggtacat attaaaacgc tattttaatt atatgttaaa ttataaagtt tggtatctaa
     4501 ctcttcttgc aggattaatt cctttcattc ctattaaatt ctctcttttt aaatttaata
     4561 atgtgaataa tcaagcgccc acagttgaaa gtaagtcaca cgacttgaac cataacataa
     4621 ataccaccaa acctattcaa gagttcgcaa cagatatcca taagtttaat tgggattcaa
     4681 ttgataatat ctgcacagtt atttggatag ttttagttat tattttaagt tttaaatttt
     4741 tgaaagcctt attatatctt aaatatttaa agaaacagtc actttatcta aacgaaaatg
     4801 aaaaaaataa aatagatacg atacttttca accatcaata taaaaaaaat attgtgattc
     4861 gaaaagcaga gactattcaa tctccaataa ctttttggta tgggaaatat attattttga
     4921 ttcctagttc atattttaaa agtgtaattg acaaaagact aaaatatata atattgcatg
     4981 aatatgctca tgctaaaaat agagatactt tacatttaat tatctttaat atcttctcta
     5041 ttattatgag ttacaatcca ttagtacata ttgtaaaaag aaagataatt catgacaatg
     5101 aagtagaagc cgatagattt gtccttaata atattaacaa aaatgaattt aaaacttatg
     5161 cggaatctat tatggactcc gtattaaatg ttccattttt taataaaaat atattaagcc
     5221 attcatttaa tggtaaaaag tcattactca aaagaagatt aattaatata aaagaagcca
     5281 atctgaaaaa acagtccaaa ttaattctaa tttttatttg tatttttact tttttgctca
     5341 tggtaattca aagccagttt ttgatggggc aatccataac tgattataat tataaaaagc
     5401 ccttacacaa cgattaccaa attttagata aaagtaaaat ttttggttca aatagtggat
     5461 ctttcgtcat gtacagcatg aagaaagaca aatactatat ttataacgaa aaagaaagta
     5521 gaaaaaggta ttctcctaat tcaacttata aaatttattt agctatgttt ggacttgacc
     5581 gacatattat aaatgatgaa aattcacgta tgtcatggaa tcataagcat tacccttttg
     5641 atgcttggaa taaggaacaa gatttaaata cagcaatgca aaattcagtt aattggtact
     5701 tcgaacgtat tagcgatcaa ataccaaaga actatactgc gactcaactc aagcaattaa
     5761 attatggtaa taaaaatttg ggaagttata aaagctattg gatggaagat agtttgaaaa
     5821 tatctaatct tgaacaagta atagttttta aaaatatgat ggaacaaaat aaccatttta
     5881 gtaaaaaagc aaagaatcaa ttatcttctt cattattgat taagaaaaat gaaaagtatg
     5941 aactgtatgg gaaaacaggt acaggtatag taaacgggaa gtataataat gggtggtttg
     6001 taggttacgt aattacaaat catgataagt attattttgc tacacattta tcagatggaa
     6061 agccatctgg gaaaaatgct gaattaatca gtgaaaaaat attaaaagaa atgggtgttt
     6121 taaatggcca ataagcaagt tgaaatatct atggctgaat gggatgttat gaatataata
     6181 tgggataaaa aatcagtatc agctaatgaa attgtagttg aaattcaaaa atataaagaa
     6241 gttagcgata aaacgattag aacattaatc acaagactat ataaaaaaga gattataaaa
     6301 cgatacaaat cagagaatat ttatttttac tcatcaaata ttaaagaaga cgatattaaa
     6361 atgaaaactg ctaaaacctt tcttaataaa ctgtatggag gggacatgaa aagtttagtg
     6421 ctgaattttg cgaaaaatga agaattaaat aacaaagaaa ttgaagaatt gcgagacatt
     6481 ttaaatgata ttagtaaaaa gtaattagag atatgtttca aacataatac atatgtaaac
     6541 tatgcttgac tcttattaaa ttagttttgt taataacatt taaaatatat tattaaagat
     6601 gagagtgtac agaaaataac cattttctat acactctctt tttatgtcta tatatatagc
     6661 gagtatacat attttagtgt tcaataaccc aacagaaaat ctatgttcat aaatatggtt
     6721 agaattaagt tatgatacaa tgaagatgta tataggaggt ttgtattttg aaaataggtt
     6781 atgcaagagt ttcaactggt ttacaaaatt taaatttgca ggaagatcaa ttaaatcaat
     6841 atggttgtga aaagatattt agcgaccaca taagtggatc aaaaagtaaa cgtcctggtt
     6901 tagataaagc cattgaattt gcgagggcag gagatacgat tgttgtttgg agactagata
     6961 gactagggcg taatatggaa gatttaatca cattagttaa tgaacttaat aatcgaggcg
     7021 tgagttttca tagtttagaa gaaaatataa caatggataa atcaagttct acaggacaat
     7081 tgttatttca tttattcgca gcatttgcag agtttgaacg caacttaatt ttagaacgtt
     7141 cttcagcagg acgaattgcc gctcgtgcta gaggacgcta tggaggtcgt cccgaaaaat
     7201 taaataaaca agatttaaag ttactcaaaa cactttatga taatggaaca ccaattaaaa
     7261 ctattgcaga acaatggaaa gtttcacgta ccacaatcta tcgttatctc aataggttaa
     7321 ataatcaaga aaataaagat aaataatatt actaagtttt aagaaagata aaaatagaca
     7381 ggacacaccc taaccataca aaaagaattg ttgaaattat aacaattaaa acgtatgatt
     7441 agggtgtata tttattatgg agtgaagatg aatgattata ggttatgcga gagtatcatc
     7501 gatagatcaa aatttagaaa gacaattgga taatttaaag acgtttggtg tggagaaaat
     7561 ctttacagag aaacagtcgg gaaagtcagt ggaaaataga cctgtatttc aagaagcact
     7621 caattttgtc agaatgggag atcgattcgt tgtggaatct attgatcgtt taggacgtaa
     7681 ctatgatgaa attattgaaa ctgtgaatta tttaaaagaa aaagacgttc agttaatgat
     7741 taccagctta cctatgatga atgaagtaat tggcaatcca ttactggata agtttatgaa
     7801 agatttaatc attcaaatat tagcaatggt ttcagaacaa gagagaaatg aaagtaaacg
     7861 tcgacaagcg caagggattc aagttgcgaa ggaaaaaggc gtatataaag ggcgcccttt
     7921 actttattca ccaaatgcta aagacccaca gaaacgtgtt atttatcatc gcgtggtgga
     7981 aatgttagaa gaaggcaaag cgattagtaa gattgcgaaa gaagttaata tcacaagaca
     8041 aacagtttat agaattaaac atgataaggg attatcttga taaattgatt gtcaatgcaa
     8101 atgagcgtct ctcacagtgt ctcaaattcc ataacatatt attgaattga gattttaata
     8161 attatacaag aaaaaagagt acgagttcgc agctttctat atagtaattg ttttactaat
     8221 aaggtgtttt aaaatatatt ataatgtaaa aagtatttga catttgtatc aaaaatattt
     8281 acactcataa atgtcaaata ctttttacat ttatgaggtg ttataatgaa tttaattcct
     8341 tttattatta ttttaatttt ttcttgttta tggacggcta taactaacaa atatttacct
     8401 tcagaaacat tagataaaaa aggacaacaa gatcgatacg atgaaagaca acgtaaaatg
     8461 tttattgaaa tactggctaa aagttttatt tggattgtat attgtatgtt atttacacta
     8521 gtgcttaaat ttacaggttt gtcaccaagt attgaaggat cttggttttc tcaatatcca
     8581 gaaattttct ttataattgt agcactattt cttatgctgt ttaattacta tactacaaat
     8641 aaaaaatata catctaaagg ttaaattaat gaaaaataga attagagaat atagaaaaca
     8701 aaaaggaatt tctcaagaaa ctttaagtaa agaattaaaa gtgtctaggc aaactattaa
     8761 tgcaatagaa aacaataaat atgatcctac attgacatta gcatttaagt tggcaagatt
     8821 gtttgataca actgtggatg aattattttc ttaaccattc atttatcaca aaaagagagt
     8881 gcgaattcgc actctctttt tgtgtagtag tactattaaa ttttgtctca ataacgaacg
     8941 taatttagaa ataatattta ttggtatttc aagaatatat atataattat ttactaagtc
     9001 catttaaaaa aatttgagag aacttgttca taagtttaat tctttcatta atattttgtt
     9061 catgtgtaaa ggtaacaatt ccattaacag cgtttgctgc tattttacta acagcattaa
     9121 catcattaat acaccattcg ccatttaaat taccctcctt aaaaattaca tgataagcat
     9181 ctatatattt gttttctaat ttattcattt tttcattaat gctattagtt ttataatatt
     9241 cagtgtaaaa ttcaattatt gcgttttgaa gtggataata gtattcggtt gttaaagata
     9301 gttcattata taaataaaat ttttctctat tagttttaca tttgatttgt tcctttttcc
     9361 actgttcttg ccatttagat tcttctatat ttaaaatttc taaaaataga ttttcttttg
     9421 ttttaaagtg ataataaaga ttccctttac tactttctga taatttaaca atttctccag
     9481 tagtagtggc attatatcca ttttttataa ataattcctt tgcgacacct agtattttat
     9541 ctttcaagtt catcacgcct ttaatgagta ttaagtacta tcaatgatag cacaaaaaat
     9601 tcaaagaata attgtataac acaatacagc catttaaatt tcgcaagatt ttttgttgta
     9661 atatgtaaaa aaatagatta taatccttat agaccgatcg aacggtctat aaggattgga
     9721 gggaacttaa atgatttcat tttttacaaa aactactgat atgatgacat caaaaaaaag
     9781 atggactgca ctagtagtat tagctgttag tttgtttgtt gttacaatgg atatgacaat
     9841 attaattatg gctttaccgg aattagtaag agagttagag ccttctggta cccaacagtt
     9901 atggatagtt gatatatact ctcttgtttt agctggcttt ataattccat tgagtgcctt
     9961 tgctgataaa tggggaagaa aaaaagcatt attaactgga tttgctttat ttggcctcgt
    10021 ttcattagct atatttttcg cagaaagtgc agagttcgta atagctattc gatttttact
    10081 tggtattgca ggtgctttaa taatgccaac tactctttca atgataagag taatttttga
    10141 aaaccctaaa gaaagggcca ctgcattagc tgtatggtca atcgcttcat cgataggtgc
    10201 tgtttttgga ccaattatcg gaggagcttt acttgagcaa ttttcatggc actcggcatt
    10261 tttaattaat gtaccgtttg cgataatagc agttgtagca ggtttatttt tattaccaga
    10321 gtctaagtta tcaaaagaaa agtctcactc gtgggatatt ccttctacaa ttttatcaat
    10381 tgcaggcatg attggactgg tatggagtat caaagaattt tcaaaagaag gactagcaga
    10441 tattattcca tgggttgtaa tagtattagc aattaccatg atagtgatat ttgttaaacg
    10501 taatttatca agttctgatc caatgttaga cgtaagactt tttaaaaaga gatcattttc
    10561 agctggtaca attgctgcat ttatgacaat gtttgcaatg gcatctgttt tgttattagc
    10621 ttcacaatgg ttacaggttg tggaagaact ttctcctttt aaagctggct tatacctatt
    10681 acctatggca ataggagata tggtgtttgc accaattgca cccggattag cggcgcgatt
    10741 tggaccgaaa atagtgttac cttccggaat tggaattgca gccattggca tgtttattat
    10801 gtatttcttt ggtcatccat tatcatattc tacaatggct ttagcattaa ttttagttgg
    10861 agctggtatg gcttcactag cagttgcatc tgctctaata atgttagaaa cacctacatc
    10921 aaaagcaggt aatgcagctg ctgttgaaga gtctatgtat gaccttggaa atgtttttgg
    10981 tgtagcagta cttggtagcc tatcttctat gctttatcgt gtatttttag atatttcatc
    11041 tttttcatca aaaggtatag ttggagattt agctcatgta gctgaagaat ctgtagtggg
    11101 cgctgtcgaa gtagctaaag ctacggggat aaaacagctt gcaaacgagg ctgtaacatc
    11161 atttaatgat gcttttgtag caactgcttt agtaggtggg attatcatga ttatcatttc
    11221 aatagttgtc tatttgttaa ttcccaaatc acttgatata actaaacaaa aatagtacta
    11281 aacatatatt tttagatatt gtagattagt ttatttttaa aattagtaat agttaaaaag
    11341 tagaaccatt aattttaaat ggttctactt ttttattatt aagtaaaatt ataaaagaca
    11401 atttcttaaa ttaataatat gatataccta tatctaataa tttattagta ttaataaacc
    11461 ttgaaaggat gattaactga tgaatagagc agatattttt aaaatatttg atgtagaact
    11521 taatataact atatttttag gagcactagt agcaactttc atctatttta taagttacat
    11581 gaacaatgta aatgaattaa ttacattatg cttaacatta gcttttcctg catatttatt
    11641 aaaaattagc agatcgttcg aggttatttt attagaggaa aaaataaaaa atagtaaaat
    11701 caaaatctgt gacaaagata gaattgaacg agagatactg gtgaaaaaga acctaataga
    11761 tgaactattg tttcctaata gagttattaa aaaatataca ctgacaattt taatttacag
    11821 tataggtatt attattcttt tactactttg taatatgtta agttatggaa ttggtgaaaa
    11881 tgtcaatttt atctggagat tactagcttg ttatgtaacg agtgtcacag tgattatagt
    11941 tgccttgatt ataatgataa tgatatttga tcttataatt ggattactat taaattttca
    12001 aatattttta aaaaataaaa agtatgatga ctttttataa ttattcgatt tatataatga
    12061 aaaattaaat gattaaacat agaaacctca aaacaaacca tatttaatag agtttatggc
    12121 gccttataca aataaaggct atgctgttaa agaattatgt agctatcttc agattaatat
    12181 ggatgatgtt tatactattg gcgatagaaa attgatttac ctatgtttaa taccctagat
    12241 aattcttctg ataatttagt ttttgttaga gtttaacata actgatgatt accagaagtt
    12301 ctcactatat aaaaggcact aaaagttata aacttttagt gcctaattaa ttattttagc
    12361 taccaaacaa acgactccaa aacccctttt taggtgtttc tacttccctg tcctcaggtc
    12421 cactctctat ttcttcagat agtttatcat ctctctttaa tacgtcttcg tttgaactgt
    12481 catccttttt cgctttagtt atgcccttat gatttaattc tgcttctatt ggttgtattt
    12541 tcttttgttg ttggttgcta ttttgatatt cttcagtaaa agttgcttct tgcggattaa
    12601 tgctttgtct atcattagtc gctgtatcaa aagagtaatt aagctgtctt tcttcttcta
    12661 attggttttc tagtttttga atctttttat tactttctaa agctaatatt tgttgattct
    12721 ccaacagttt atttaatgta ttaacattgc tattttgttg atctagttgt ttagttaaat
    12781 tctcaatata tttttcgtca tttttagctc tagtttcaaa gatttctatt tgcttttcta
    12841 attcatttac ttttgttttt aatgactcaa aaccatttga attattgtat atatgctttt
    12901 caaactctgc agtattttca ttaaatcttt ctttttttat tgattcttta ttttgcattg
    12961 tcctttcttt cttagtgatc ttttctataa tttttaaaca atcattatca ttaatataat
    13021 taattccatt ttctttttta aaagatatat ttaagttttt agcattatta acaatagttt
    13081 gtttagttac attcaattca tcagcaacca ttttaatagt tttcataaca ttcatcctta
    13141 ggtacataaa ttggtaccta aattttacca cctaacaaat attttttcat ctttcgacat
    13201 ctaaatttac tacctatttc actactttag tacctaatta gccgttaaaa ccttctatag
    13261 gtgactaatt aggtactaaa gtggtgaatt tttatcattt taaagttaca atgttctttc
    13321 aactaaactt aaaaagcttt atatacaatc ttaaaagtgt taatattact ttgtgaatat
    13381 taaaagagtc gatactattg gcgtagcatc gactctcggt aataaaacga ttcgcattcg
    13441 tctgtttata taattttttg atacttgtat tatatatatc taatcatata agtgcaagta
    13501 caaaacatat aacctacgta aaaattgttt tattacctct atccaaaaag tggaaatgag
    13561 gtttttatta tgcccaattt tgagaaatac aatttatcac aagtaaaaac tgaaagattt
    13621 taccaacttc ctaaatattt gttcgaagat gcatatttta agaaaatgtc agcagaagcc
    13681 aaaattatgt atgcattatt aaaagatcgt ttcgaattat ccatccaaaa tgaatgggta
    13741 gatagaaata ataacattta ctttattttc agtaataaac atttgtgcga gtacttaggt
    13801 tatggagaac aaaaaatcat aaaattgaaa aaagagttag taaattttaa tttattaact
    13861 caagagcgtg ttggccttaa taaaccaaat agattatatt tattaaaacc aaattatgat
    13921 attgaagcaa gtcttaccaa ggaacttcca aattcacagt tccagaacaa tgaatttgga
    13981 agttctagaa ctgtgaattt aagtggtcaa gaacttccaa attcacagtc taatgatact
    14041 gagttaaata atactaatta tatagaaaat gaggataatg atacgtatga tatgaatgat
    14101 attatatcta atactttaat aaataataat catcattcga atcatacaaa tcatcaaaaa
    14161 actgaattta ataatgacgc ccttaagttc caagtactcg aagaattgcc acaacaactt
    14221 caagactatt taagtaaatt tgaaattaga gaaattcgga ttattaaaag cgtattactc
    14281 aaagggaaaa agtcatttaa tacttcacat gatacttatt atcgtttaga agatgttgag
    14341 tttgaaattg taagtgtatt gaaacgtttt aaagcgatgt tgctacaaaa gaatgaaacc
    14401 gttgaagcta tgcaaggtta tttaatgcaa tccattaaag ctgaacttga agaaacacat
    14461 gccctttata tgcgccgtaa aaacatgaaa caatataata tctttaatca ataattcaaa
    14521 tgattttata acaatcaaag agacatcaaa atattccgtt aaatcatctg actttttaac
    14581 tgatgacgac gaaaaaaatc aagaaatttt aagtgatcta gaaaaggttt gtatcgaaaa
    14641 cgtatgttaa gttatggtgg attacttaaa gaaaagcata aaattttaaa cttagacgat
    14701 gccgaagatg gtaatttgat taatacaagt gatgaagata aaacgacaga cgaagaagaa
    14761 aaagcacatt cgattacagc aatttggaat ttcgaaaagc aaaattatta tttaaaaaat
    14821 ttaaggagtt aaaaatatga acactaaaat tttaactgga atgactggaa gttctttaga
    14881 acgaaaaatc aataatttta ttaatgataa ccaaatcgaa gtcattgata ttaagttttc
    14941 aagttctgta ttttattttg gggtaatgat tatttataaa taattaaaga gtttaagaca
    15001 ttagtgatga ctgatgtctt tttttactgt ttttttataa aaaagtactg gcttattttt
    15061 gtgacaaatg caatatattg tgtcacaaaa gtgtgacact taagcttttt atgaccccac
    15121 ataaaaatat tgttgaagct ttgaattgtc tggctttgcc agatacccca tgtatacata
    15181 gggtcaaatt tcccttatgc tcttacggag ttacggagtt cttagagaaa aaataaaaat
    15241 tctcgatttt gataaaaaat gtcttgcagg aatttagaaa aacatggggg aagttttaaa
    15301 ggattttatg ctaactttta atttgcatgt aaatgggcag tgtttaaaaa aatagtcatt
    15361 ggttttattt aaaattttgt ttttgaaaat agcatatatg tatttggttc atatttgcgt
    15421 tttaagagat tatgtaggtt ttagatagaa aactatatga tttaccccta aatctttaaa
    15481 ataccccctt aaaattcaaa ataaaggtat ttataatttg agtaagtctt gtgataaagt
    15541 tttttaaaaa ggagttttta ttttgaataa agacacaatg ttagataaag gttacgttat
    15601 agcaactatt ttaaatgttt tctttttact tggattaatt tttatatctc atttggaaaa
    15661 tttatatata ttaattccgt atgttatttt gatgggaata aatgctattt atttggttgt
    15721 taaagttatg aatttcaaaa agaataatta gaatatttga ggggattttg aaacgagttt
    15781 cttcttgttt tcacactatt ttttattcct attggtgttg ttgcttactt tttgtttttc
    15841 tatgaagatg atgattttga cgagatggaa gaaaaatatg attatcatga agataaaaaa
    15901 atagacgacg catttatgcc gagaaaattt attgatgttg agaagaaccc ttaactaaac
    15961 ttgaagacga atgtcggcat agcgtgagct attaagccga ccattcgaca agttttggga
    16021 ttgttagggg ttccgaggct caacgtcaat aaagcaattg gaataaagca cctatgatta
    16081 tttaaaaata ttagttataa tacattcaaa aatatttttg aatgaggtgt atgtatgatt
    16141 caaacggttg tcactgctgc tattctttat attgctacag catttgattt attagtaatt
    16201 ttattaatat tttttgctag agcaaagact aaaaaagaat atagagatat ttatattggt
    16261 caatatttag ggtctattat tttaatatta gttagtttgt ttttagcttt tgtattaaat
    16321 tatgtttcag agaagtggat attaggttta ttgggtttaa taccaattta tcttggaatt
    16381 aaagtggcta tttatgtgat tgtgaaggag aaaagagagc taaaaaagaa ctgaatgaaa
    16441 aaggattgtc taaattagtt ggtacggttg caattgttac gatagcaagt tgtggcgccg
    16501 ataatattgg tttatttgtt ccgtattttg tgacattaag tgttactaat ttattactta
    16561 ctctgtttgt ctttttaatt ttaattttct tcttggtgtt tactgcacaa aaattagcta
    16621 atatcccagg aattggagaa attgttgaga aatttagtcg ttggattatg gctattattt
    16681 atatagcttt aggtttattt attattattg aaaatgacac tattcaaaca attttaggat
    16741 ttatatttta atttagggtg tgattttata tgagttatga aaatacttgt gatgtgatct
    16801 gtgtacatga ggataaagtt aacaatgctt taagtttttt agaagatgat aaatctaaga
    16861 aattacttaa cattttagaa aaaatttgtg atgagaagaa attgaaaatc atattatctt
    16921 tgattaaaga agatgagttg tgtgtttgtg atatttcttt gatattgaaa atgagtgttg
    16981 cttcaacttc acatcattta aggcttttat ataaaaatga ggtacttgat ttttataaag
    17041 atggaaagat ggcatattat tttattaaag acgatggaat aagagagttt ttctctaaaa
    17101 atcatgaggg tttttgaaac gagtgaaacg agtttcttct tgtcttgata ctatatagaa
    17161 ataacgttct tttctaaaat ccttttgaag cgttgatatg acggcgtttc atactgtttt
    17221 gcttggggaa aataaaattt gacataaaaa aactccagta atatgattaa ggtgtctaat
    17281 ctaaatcaat actggagttc tttttatatg caatataata ctactagaag tataaccgaa
    17341 aatcaagata ataaaacgtt aaaagatatg acgaaaagtg gaaaacaacg cccatggaga
    17401 gaaaagaaaa tagataatgt aaggttctgt tgcaaagtta aaaaataagt gtctaacctt
    17461 atgtttaaag taatactttg tattaactag ctagcatgat gctaattaca cggcatggcg
    17521 aaaacccgta gatctgaaga gatctgcggt tctttttata tagtccataa atacattcaa
    17581 tgcctgtgta ttttattcca attgctttat tgtcgttgag cctcggaacc cttaacaatc
    17641 ccaaaacttg tcgaatggtc ggcttaatag ctcacgctat gccgacattc gtctgcaagt
    17701 ttagttaagg gttcttctca acatcaataa attttctcgg cataaatgcg tcgtctaact
    17761 ttttttataa tgtttatcaa accacgatga aaaaaatata aaaaagactg tataaagaat
    17821 aaaccaagta tctaaatgat tttgattcat ttgcttataa ataaaaaaca ataaaaaaat
    17881 accaagaata atttgtaaaa taaataaaga cctcttcaaa aaaccactcc ttttaaaaaa
    17941 ctttatctca ggacttattc aaattataaa cacctttatt ttgaatttta agagggtatt
    18001 ttaaagattt agaggtaaat cttatagtct tctacttaaa aatctataca agctcttaaa
    18061 acgcaaatat gagtcaaata aatatatggt aatttcacaa acaaaaattt cagcaaaacc
    18121 agtgactaat tttttaacac tgcccattta aatgcaaatt aaaaatgagc ataaaatctt
    18181 ttaaaacttc cccatgtttt tctaaattcc tgcagggcgt ttttatcaaa aatcaagaaa
    18241 tttcaatttt tctctaagaa ctccgtaaga gcataaggag aatttgctat cattcaaaaa
    18301 taataggtct ggcaaagcca gacattccaa gggttttaag taattttaaa gtgatatcat
    18361 aaaaagctgt agtgtcacac ttttgtgaca ctacatacag catttgtcac aaaaataaga
    18421 cagtactttt ttacaaaaaa tcaataaaaa agacatcagt catcactaat gtcttaaata
    18481 ataattttgc ttttcaaaat tccaaattgc cgtaattgaa tgtgcttttg cttcttcatc
    18541 tgttatttta tcttcatcac ttgtattaat taaattacca tcttcggcat cgtctaagtt
    18601 taaaatttta tgcttttgtt taagcaatcc accataactt aacatacgtt ttcgatataa
    18661 acctttttct aaatcactta caatttcttg atttttttcg tcatcgtcag ttaaaaaatc
    18721 agatgactta accgaatatt ttgatgtctc tttgattgcc gattcaatat ctttatcgcc
    18781 tttttgatta ggtttaattg ctttaatatt tacaacaggt cgataatcaa cttgtaatgc
    18841 tttttgccat aaattaaccc attcttcttg agttatataa ttctcttttt ttctaaaata
    18901 tgcattttca acacataaca aaacgtgcat atgctgatta taactaccgt catttttatt
    18961 aacggtaact tctgttgaac gcataaatcc aacaagattt tgtttaacct ttttatatct
    19021 actcaaccta tcaaatgctt tagttagatg cttcaaactt tgttctaaag tatctccatc
    19081 tatcgcattt tttgttgaaa gtgttaaaaa caaccaacgt gcttttggct tttccttaat
    19141 tacttcttca atcacttttt gagcttgata actatttttc atagcacgcc tccaattaca
    19201 aactggacat agctttgatt tacaaaacca cgtcttatgt aatttcaaat aaccttcatc
    19261 ggtcggcttg aattctaaga cgttaccaca ttgttttacg ttataagcct tttttatttt
    19321 taaaatttca agtatatctg catagcttac attaggttct gttgcaaagt tagaaatata
    19381 gtataatagt caacaaaaaa tgaggtgcag aggatgaatt atttcagata taagcaattt
    19441 gacaaagatg tcattactgt agccgttggc tactatctaa gatatgcatt aagttatcgt
    19501 gatatatctg aaatattgag agaacgaggc atctatgttt atcattcaac aatttatcga
    19561 tgggtacagg aatatgctcc tattttgtat caaatttgga agaaaaaaaa taagcaagct
    19621 tattataaat ggcatataga tgagacgtat atcaaaatta aagggcaatg gaattattta
    19681 tatcgcgcta ttgatgcaga tggccataca ctagatattt cgttacgtaa gaaacgagat
    19741 aatcactcag catatacgtt tattaaacgt cttattaaac aatttggcaa acctcaaatg
    19801 ataattacaa accaagcccc ttcaacgaag gtggcaatgt ccaaagtgat taaagatttt
    19861 aaacttaccc ccaactgtca ttgtaactct aaatatttaa ataatctcat tgaacaagat
    19921 catcgtcata tcaaagtaag gaaaataagt tatcaaagta tcaatacggc aaagaatacg
    19981 atcaaaggca ttgaatgtat ttatggacta tataaaaaga accgcagatt tcttcagatc
    20041 tacgggtttt cgccatgccg tgtaattagc atcatgctag ctagttaata cgaagtatta
    20101 ttttaaacat aaggttagac acttattttt taactttgca acagaaccaa gaaatcgatc
    20161 caactgaata cctttaccaa atttattata tttggaatca gaaagagtac ctggcaagtg
    20221 aacttcacga acttaccgaa gaagaacaat aaaaaaatat aaaaatattt tgagagttga
    20281 ccacccacat ttgtagttta cggagaacgt gggtggtcaa ctctcaaaat ttatttctta
    20341 aaaatttatt tgttgttctg atgagcgatg aacgactaaa aaagtataat gctattttct
    20401 atcattacac tttttttata cgcttattat actttcgtta tactcttttt gtcgctacac
    20461 gaactatgtg atcaaacggc acgtttgccc atttaaaatg caaattcgga acgatttatt
    20521 gctaattttt aaatttgcat gtaaatgggc agtacgtaaa aatcgcccgt cctggtgtcg
    20581 aaaaaacgaa cagaaaaaat aaaattaaaa tatagtaatc tttttatttt ttacaggtag
    20641 gtttccccat aatttagtac tgcatcagaa atttatctgt acttagaaat gacgacgtat
    20701 tttttctata cgtttatgac atttattcta cattgatcca aatcataaaa atgtgtttaa
    20761 aatgtcctaa aaaggtttta aaaggacgat ttttttatat tacgtatttt tgtactcaaa
    20821 attagagaat gctctaaatg acctcttaaa acgcaaaaaa aatatatatc aaaaagacat
    20881 gtatttttaa aaaaattgat gtgtatgatg catgtctttt gtgtatgttt tatatacata
    20941 aagtatatgt atacgtaacc tgtatgtata cataacgtta tggtttttat acatatgagt
    21001 taaaaaagtg atgtcacttt ttttctagga aaaataactc ggcactgccg agttcaccac
    21061 gttatgggtc tgccaaaata taaaagtggt ggcactttcc cttatgctca tgactttatg
    21121 tataaaagtt agaggtactt ttatgccgag aaaacttttt gagagattaa tttttttatt
    21181 tttttatttt ttacttttat tttcttcaaa tattttgtaa atctctttat gagtaaataa
    21241 aagatagaag cataaagaat aaatgaaaat ttgaaaatat aagtttatat gaatgttgta
    21301 gaaaatcttc aaaattatta agtttaatac gatcatatta gcagttataa agaatatgaa
    21361 taagataata ttattaaatt tctttttgta ttttatatgt aaaaatatta taaaaagttc
    21421 aagaaaaata aatattagat aagttactat aaagaataat gcaatatagc caatgttata
    21481 aaacatatta tttgaatacc aatttattgt tattaaagaa cttatattta aattatctgc
    21541 taatgattgg aaacctatta tgctaaaaaa tggtattgag aatactaata cggatatagg
    21601 tatgattatt attccgagta agaacgttac aattataaag ttcaataagt actctttgtt
    21661 ta
//
LOCUS       DAPDIM010000048        21152 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000048 DAPDIM010000000
VERSION     DAPDIM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21152
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.048"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            219..1448
                     /locus_tag="RFE25_001936"
     CDS             219..1448
                     /locus_tag="RFE25_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDU2816982.1"
                     /translation="MFLLINIIGLIVFLGIAVLFSRDRKNIQWQSIGILVVLNLFLAW
                     FFIYFDWGQKAVRGAANGIAWVVQSAHAGTGFAFASLTNVKMMDMAVAALFPILLIVP
                     LFDILMYFNILPKIIGGIGWLLAKVTRQPKFESFFGIEMMFLGNTEALAVSSEQLKRM
                     NEMRVLTIAMMSMSSVSGAIVGAYVQMVPGELVLTAIPLNIVNAIIVSCLLNPVSVEE
                     KEDIIYSLKNNEVERQPFFSFLGDSVLAAGKLVLIIIAFVISFVALADLFDRFINLIT
                     GLIAGWIGIKGSFGLNQILGVFMYPFALLLGLPYDEAWLVAQQMAKKIVTNEFVVMGE
                     ISKDIASYTPHHRAVITTFLISFANFSTIGMIIGTLKGIVDKKTSDFVSKYVPMMLLS
                     GILVSLLTAAFVGLFAW"
     gene            1703..1795
                     /locus_tag="RFE25_001937"
     CDS             1703..1795
                     /locus_tag="RFE25_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816983.1"
                     /translation="MFCYYKQHKGDNFSIEEVKNIIADNEMKVN"
     gene            1973..2806
                     /locus_tag="RFE25_001938"
     CDS             1973..2806
                     /locus_tag="RFE25_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDU2816984.1"
                     /translation="MNKTVKDLILVVLGSFIFAAGVNAFIISGNLGEGGVTGLAIILY
                     YAFHISPAITNFLVNAVLIAIGYKFLSKRSMYLTILVTILISIFLSLTESWQVETGNS
                     IVNAIFGGVSVGLGIGVIILAGGTTAGTTILARIATKYLDVSTPYALLFFDMIVVAIS
                     LTVIPLDKVLVTVISLYIGTKVMEYVIEGLNTKKAMTIISTNPDKLAKAIDEQIGRGL
                     TILNGHGYYTREEKDVLYVVISKTQVSKAKRLIKQIDKDAFLVIHDVRDVYGNGFLAD
                     E"
     gene            3088..3885
                     /locus_tag="RFE25_001939"
     CDS             3088..3885
                     /locus_tag="RFE25_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2816985.1"
                     /translation="MNRLHGQQVKIGYGDNTIINKLDVEIPDGKVTSIIGPNGCGKST
                     LLKALSRLLAVKEGEVFLDGENIHTQSTKEIAKKIAILPQSPEVADGLTVGELVSYGR
                     FPHQKGFGRLTAEDKKEIDWAMEVTGTDTFRHRSINDLSGGQRQRVWIAMALAQRTDI
                     IFLDEPTTYLDICHQLEILELVQKLNQEQGCTIVMVLHDINQAIRFSDHLIAMKEGDI
                     IATGSTEDVLTQEILEKVFNIDVVLSKDPKTGKPLLVTYDLCRRAYS"
     gene            3921..4925
                     /locus_tag="RFE25_001940"
     CDS             3921..4925
                     /locus_tag="RFE25_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDU2816986.1"
                     /translation="MTNRENPTPLKFLSYIIGLSMILLITLFISTLIGDAKIQASTII
                     EAIFNYNPSNQQQNIINEIRIPRNIAAVIVGMALAVSGAIIQGVTRNGLADPALIGLN
                     SGASFALALTYAVLPNTSFLILMFAGFLGAILGGAIVLMIGRSRRDGFNPMRIILAGA
                     AVSAMLTALSQGIALAFRLNQTVTFWTAGGVSGTTWSHLKWAIPLIGIALFIILTISK
                     QLTILNLGESLAKGLGQNVTMIRGICLIIAMILAGIAVAIAGQVAFVGLMVPHIARFL
                     IGTDYAKILPLTALLGGILVLVADVIARYLGEAPVGAIISFIGVPYFLYLVKKGGRSI
                     "
     gene            4922..5938
                     /locus_tag="RFE25_001941"
     CDS             4922..5938
                     /locus_tag="RFE25_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDU2816987.1"
                     /translation="MISSNNKRRQLIALAVFSILLFLGCTWSITSGEYNIPVERFFKT
                     LIGQGDAIDELILLDFRLPRMMITILAGAALSISGAIVQSVTKNPIAEPGILGINAGG
                     GFAIALFIAIGKINADNFVYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGV
                     GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFK
                     SNTLNIIHTGDNIARGLGVRLSRERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAK
                     RIVGPRHQLFLPIAILVGACLLVIADTIGKIVLQPGGVPAGIVVAIIGAPYFLYLMYK
                     TKNV"
     gene            6172..7140
                     /gene="dhaK"
                     /locus_tag="RFE25_001942"
     CDS             6172..7140
                     /gene="dhaK"
                     /locus_tag="RFE25_001942"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDU2816988.1"
                     /translation="MMKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHG
                     VAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSPTPDKILEAIKAVDTGDGVLLVV
                     KNYAGDVMNFEMAQELAEMEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLA
                     EKGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKG
                     IHREEVKDIDHIVGTLLDELYKEVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAAR
                     TVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQYFK"
     gene            7182..7766
                     /gene="dhaL"
                     /locus_tag="RFE25_001943"
     CDS             7182..7766
                     /gene="dhaL"
                     /locus_tag="RFE25_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HDU2816989.1"
                     /translation="MKVNDMKARLLNLEETFKKHESELTELDRAIGDGDHGVNMVRGF
                     SSLKDKLDDSSMQSLFKSTGMALMSNVGGASGPLYGFSFVKMSAVTKDDMDNQDFITL
                     IKAFAEAVESRGKVTLNEKTMYDVVARAAEKLENGETLTFNDLQQLADNTKDMVATKG
                     RAAYFGEESKGYIDPGAQSMVYILNALIGDEDNA"
     gene            7759..8121
                     /locus_tag="RFE25_001944"
     CDS             7759..8121
                     /locus_tag="RFE25_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HDU2816990.1"
                     /translation="MPKIILVSHSKEIASGTKSLLKQMAGDVDIIPIGGLPDGSIGTS
                     FDIIQEVLTKLEDDALCFYDIGSSEMNVDMAIEMYDGNHRVLKVDAPIVEGSFIAAVK
                     LSIGGSIDDALAEIKQSF"
     gene            8237..8734
                     /locus_tag="RFE25_001945"
     CDS             8237..8734
                     /locus_tag="RFE25_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816991.1"
                     /translation="MQHLIKKHVLNGEFDLVRQLMSETDFMEFEEAYISSAHEVESMM
                     FYTCILDMIKYEESSEMHDLAFLLLVYPLSEYEGALDSAYYHADASIKLTDGKEVKSL
                     LQMLLLHAIPTPVISDKKAFDIAKQILKLDPNNNVARNVLKDTAKRMDNVVVDINELH
                     QRNAR"
     gene            9191..10258
                     /locus_tag="RFE25_001946"
     CDS             9191..10258
                     /locus_tag="RFE25_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816992.1"
                     /translation="MMMNKEATKIGFAYVGIVVGAGFSTGQEVMQFFTKYGLWAYLGV
                     IISGFILAFIGRQVAKIGTAFEATNHESTLQYVFGEKFSKVFDYILIFFLFGIAVTMI
                     AGAGATFEESYNIPTWLGALIMTLAIYITLLLDFNKIVRALGIVTPFLIVLVVLIAGV
                     YLFKGHVSLAEVNQVVPEASIWKGIWFGTIYGGLAFSVGFSTIVAIGGDTEKRTVSGA
                     GAMYGGIIYTVLLALINFALQSEYPTIKNASIPTLTLANNIHPLIATVLSVIMLAVMY
                     NTILGLMYSFAARFTEPYSKNYHIFIIIMMVAGYLLSFVGFAELINKLYTIMGYVGLF
                     IVVAVIIKYFKRKNADKKHIA"
     gene            10409..11452
                     /locus_tag="RFE25_001947"
     CDS             10409..11452
                     /locus_tag="RFE25_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2816993.1"
                     /translation="MNKDNKWTMITALFITVISVLLAFHLKQHYDQITNENHANKDKI
                     NIKNKNVRIYQNLTYNRVFPNSKLDIITPVDMSSNAKLPVIFWMHGGGYIAGDKQYKN
                     PLLAKIAEQGYIVVNVNYALAPQYKYPTPLIQMNQATQFIKENKMNLPIDFNQVIIGG
                     DSAGAQLASQFTAIQTNDRLREAMKFDQSFKPSQIKGAILFGGFYNMQTVRETEFPRI
                     QLFMKSYTGEEDWEKSFKNISQMSTVKQSTKNYPPTFLSVGDSDPFESQNIEFSKKLQ
                     ELNVPVDTLFYDGTHHLHHQYQFHLNKPESIDNIKKVLLFLSRNTSSSGIQTEEKPQM
                     ENPSNELPLNPLN"
     gene            11781..12209
                     /locus_tag="RFE25_001948"
     CDS             11781..12209
                     /locus_tag="RFE25_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2816994.1"
                     /translation="MTRSALKPFKNKRVMVTGRIQRVLFKNYLDRHSTFKPNVRILLK
                     DVFVSGVSIDHLWLYETNKYYALAMELIHQRVKFSANVVPYYKINRNNNLFVQDYGIK
                     RKGRLITEEAYNQNNQYQDKIYEKLPDIDFRLEDFYSKEN"
     gene            complement(12418..12924)
                     /locus_tag="RFE25_001949"
     CDS             complement(12418..12924)
                     /locus_tag="RFE25_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2816995.1"
                     /translation="MAHIIRRVSIKDVENFISMLAKIYDESPYMFYTPGEYDPSVTSA
                     SKQLEEYITSPHKVIFVAESDEQLVGFAFVNTTPFQRIKHVAKIDLGVKKLYQHRGIG
                     QALLDAIMAWCLNNQIHRIEANVPLNNQPALELFKSADFQIEGVLKDKLFIDGKYYDD
                     YMMAKILK"
     gene            13037..13960
                     /gene="graX"
                     /locus_tag="RFE25_001950"
                     /gene_synonym="apsX"
     CDS             13037..13960
                     /gene="graX"
                     /locus_tag="RFE25_001950"
                     /gene_synonym="apsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="auxiliary protein GraX/ApsX"
                     /protein_id="HDU2816996.1"
                     /translation="MKPKVLLAGGTGYIGKYLSEVIENDAELFTISKYPDNKKTDDVE
                     MTWIQCDIFHYEQVVAAMNQIDIAVFFIDPTKNSAKITQSSARDLTLIAADNFGRAAA
                     INQVKKVIYIPGSRYDNETIERLGAYGTPVETTNLVFKRSLVNVELQVSKYDDVRSTM
                     KVVLPKGWTLKNVVNHFIAWMGYTKGTFVKTEKSHDQFKIYIKNKVRPLAVFKIEETA
                     DGIITLILLSGSLVKKYTVNQGKLEFRLIKESAVVYIHLYDYIPRLFWPIYYFIQAPM
                     QKMMIHGFEVDCRIKDFQSRLKSGENMKYTK"
     gene            13976..14650
                     /gene="graR"
                     /locus_tag="RFE25_001951"
                     /gene_synonym="apsR"
     CDS             13976..14650
                     /gene="graR"
                     /locus_tag="RFE25_001951"
                     /gene_synonym="apsR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor
                     GraR/ApsR"
                     /protein_id="HDU2816997.1"
                     /translation="MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFN
                     PEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPF
                     YTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
                     EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGK
                     GYMAHE"
     gene            14643..15683
                     /gene="graS"
                     /locus_tag="RFE25_001952"
                     /gene_synonym="apsS"
     CDS             14643..15683
                     /gene="graS"
                     /locus_tag="RFE25_001952"
                     /gene_synonym="apsS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase GraS/ApsS"
                     /protein_id="HDU2816998.1"
                     /translation="MNNLKWVAYFLKSRMNWIFWILFLNLLMLGISLIDYDFPIDSLF
                     YIVSLNLSLTMIFLILTYFKEVKLYKHFDKDKEIEEIKHKDLAETPFQRHTVDYLYRQ
                     ISAHKEKVVEQQLQLNMHEQTITEFVHDIKTPVTAMKLLIDQEKNQERKQALLYEWSR
                     INSMLDTQLYITRLESQRKDMYFDYVSLKRMVIDEIQLTRHISQVKGIGFDVDFKVDD
                     YVYTDTKWCRMIIRQILSNALKYSENFNIEIGTELNDQHVSLYIKDYGRGISKKDMPR
                     IFERGFTSTANRNETTSSGMGLYLVNSVKDQLGIHLQVTSTVGKGTTVRLIFPLQNEI
                     VERMSEVTNLSF"
     gene            15827..16588
                     /gene="vraF"
                     /locus_tag="RFE25_001953"
     CDS             15827..16588
                     /gene="vraF"
                     /locus_tag="RFE25_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein VraF"
                     /protein_id="HDU2816999.1"
                     /translation="MAILEVKQLTKIYGTKKMAQEVLRDINMSIEEGEFIAIMGPSGS
                     GKTTLLNVLSSIDYISQGSITLKGKKLEKLSNKELSDIRKHDIGFIFQEYNLLHTLTV
                     KENIMLPLTVQKLDKEHMLNRYEKVAEALNILDISDKYPSELSGGQRQRTSAARAFIT
                     LPSIIFADEPTGALDSKSTQDLLKRLTRMNEAFKSTIIMVTHDPVAASYANRVVMLKD
                     GQIFTELYQGDDDKHTFFKEIIRVQSVLGGVNYDL"
     gene            16578..18467
                     /gene="vraG"
                     /locus_tag="RFE25_001954"
     CDS             16578..18467
                     /gene="vraG"
                     /locus_tag="RFE25_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease VraG"
                     /protein_id="HDU2817000.1"
                     /translation="MTFNEIIFKNFRQNLSHYAIYLFSLITSVVLYFSFVALKYAHKL
                     NMTESYPIIKEGSQVGSYFLFFIIIAFLLYANVLFIKRRSYELALYQTLGLSKFNIIY
                     ILMLEQLLIFIITAILGIIIGIFGSKLLLMIVFTLLGIKEKVPIIFSLRAVFETLMLI
                     GVAYFLTSAQNFILVFKQSISQMSKNNQVKETNHNKITFEEVVLGILGIVLITTGYYL
                     SLNIVQYYDSIGILMFILLSTVIGAYLFFKSSVSLVFKMVKKFRKGVISVNDVMFSSS
                     IMYRIKKNAFSLTVMAIISAITVSVLCFAAISRASLSSEIKYTAPHDVTIKDQQKANQ
                     LASELNNQKIPHFYNYKEVIHTKLYKDNLFDVKAKEPYNVTITSDKYIPNTDLKRGQA
                     DLFVAEGSIKDLVKHKKHGKAIIGTKKHHVNIKLRKDINKIYFMTDVDLGGPTFVLND
                     KDYQEIRKYTKAKHIVSQFGFDLKHKKDALALEKVKNKVDKSIKTRSEAISSISSLTG
                     ILLFVTSFLGITFLIAVCCIIYIKQIDETEDELENYSILRKLGFTQKDMARGLKFKIM
                     FNFGLPLVIALSHAYFTSLAYMKLMGTTNQIPVFIVMGLYICMYAVFAVTAYNHSKRT
                     IRHSI"
     gene            19192..19809
                     /locus_tag="RFE25_001955"
     CDS             19192..19809
                     /locus_tag="RFE25_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 domain-containing protein"
                     /protein_id="HDU2817001.1"
                     /translation="MFSKKKDKFMVQLEEMVFNLDRAAIEFGKMDFNTHLDLKAYSDN
                     IKTYESHGDELVHQVITDLNQTFITPIEREDILSLCDAIDDVLDAIEETAAMFEMYSI
                     EYTDEYMAEFVDNIQKAVAEMKLAVGLLVDKKLSHMRIHSINIKEFETNCDGILRQSI
                     KHIFNSETDPITLIKIKDIYESMEEIADKCQIVANNFETIIMKNS"
     gene            19825..20832
                     /locus_tag="RFE25_001956"
     CDS             19825..20832
                     /locus_tag="RFE25_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HDU2817002.1"
                     /translation="MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKT
                     AILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYG
                     IPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFK
                     VIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVE
                     PQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLH
                     FPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLAGLLFYILNLF
                     F"
BASE COUNT         7408 a         2810 c         3863 g         7071 t
ORIGIN      
        1 ataattctta aattaataaa atcgatattt taagaaaaaa atgctcatgg tataatacaa
       61 gttataagca aacatacata tattaaatac tgtagccacg agtcataatt cttcatattt
      121 tacatagcaa tttaactgat tttagagtcc acggtacaga agtttgatat ttcaatgttt
      181 ctaaattttt aaaaaattaa atcataggtg ggtgctaaat gtttttatta atcaacatta
      241 ttggtctaat tgtatttctt ggtattgcgg tattattttc aagagatcgc aaaaatatcc
      301 aatggcaatc aattgggatc ttagttgttt taaacctgtt tttagcatgg ttctttattt
      361 attttgattg gggtcaaaaa gcagtaagag gagcagccaa tggtatcgct tgggtagttc
      421 agtcagcgca tgctggtaca ggttttgcat ttgcaagttt gacaaatgtt aaaatgatgg
      481 atatggctgt tgcagcctta ttcccaatat tattaatagt gccattattt gatatcttaa
      541 tgtactttaa tattttaccg aaaattattg gaggtattgg ttggttacta gctaaagtaa
      601 caagacaacc taaattcgag tcattctttg ggatagaaat gatgttctta ggaaatactg
      661 aagcattagc cgtatcaagt gagcaactaa aacgtatgaa tgaaatgcgt gtattaacaa
      721 tcgcaatgat gtcaatgagc tctgtatccg gagctattgt aggtgcgtat gtacaaatgg
      781 taccaggaga actggtacta acggcaattc cactaaatat cgttaacgcg attattgtgt
      841 catgcttgtt gaatccagta agtgttgaag agaaagaaga tattatttac agtcttaaaa
      901 acaatgaagt tgaacgtcaa ccattcttct cattccttgg agattctgta ttagcagcag
      961 gtaaattagt attaatcatc atcgcatttg ttattagttt tgtagcgtta gctgatctat
     1021 ttgatcgttt tatcaatttg attacaggat tgatagcagg atggataggc ataaaaggta
     1081 gtttcggttt aaaccaaatt ttaggtgtgt ttatgtatcc atttgcgcta ttactcggtt
     1141 taccttatga tgaagcgtgg ttggtagcac aacaaatggc taagaaaatt gttacaaatg
     1201 aatttgttgt tatgggtgaa atttctaaag atattgcatc ttatacacca caccatcgtg
     1261 cggttattac aacattctta atttcatttg caaacttctc aacgattggt atgattatcg
     1321 gtacattgaa aggcattgtt gataaaaaga catcagactt tgtatctaaa tatgtaccta
     1381 tgatgctatt atcaggtatc ctagtttcat tattaacagc agctttcgtt ggtttatttg
     1441 catggtaata tgtcgaagag tgactatgat aatacatttt aactaataaa tatgtccagg
     1501 catgtcgtct attgatatag gtgagatgct tggacttttt tattattgat ataaaggtat
     1561 ttaaatattt ttaaagttac cgaaattgaa gcattataaa aaccaagtgc acatggtaat
     1621 acacttggct tttatgggaa atgaatatta ttgtacatat gacagtaagg actaggtaca
     1681 gtcatagtac ttcgagcaaa atttgttttg ttattataaa caacacaaag gagataactt
     1741 ctctattgaa gaagttaaaa acattatagc agacaatgaa atgaaagtaa attaaaaatt
     1801 cagaatattt ttaattatta tattgtgagt gatatttatt agggaaagct attcttcata
     1861 taaattagtt aaatagtaaa tctttgttag aactctttcc atagagttgt gacagcattt
     1921 ttgttgtgct actattttta tagtctaata aatatataaa ggggatggtt tcgtgaataa
     1981 aacggttaaa gatttaatac tagttgtctt aggttcattt atctttgctg caggtgtaaa
     2041 tgcatttatt atttctggta acttaggtga aggcggggtt acaggtttag caattatttt
     2101 atattatgcg tttcatattt caccagccat cactaacttc ttggtcaacg cagtattgat
     2161 tgccataggt tataaatttt tgagtaagag aagtatgtac ttaactattc ttgtaacaat
     2221 tcttatttca atatttttga gtttaacaga atcatggcaa gtagaaactg gaaacagcat
     2281 tgtgaatgcc atttttggtg gtgtaagcgt tggactagga atcggagtaa ttatccttgc
     2341 aggcggtaca acagcaggta caacaatttt ggcgagaatt gcaacgaaat acctcgatgt
     2401 aagcacgcca tatgctttgc ttttcttcga tatgatcgtt gttgcaattt cacttacagt
     2461 tattccactt gataaagtat tagtaacagt aatatcactt tatataggaa caaaagtgat
     2521 ggaatatgtc atagaaggtt taaacactaa aaaagctatg acgattattt caactaatcc
     2581 cgacaaactt gccaaagcaa tagacgagca aattggaaga ggtttaacca ttttaaacgg
     2641 acatggctat tatacgcgtg aagaaaaaga tgtcttatac gttgttattt ctaaaacaca
     2701 agtttcaaaa gcaaagcgat taattaaaca aatcgataaa gatgcattcc tcgtaattca
     2761 tgatgtaaga gatgtctatg gtaatggctt tcttgcagat gaataaataa atggtatgag
     2821 cacacatact taaatagaag tccacggaca agtttttgaa ctatgaagac ttatctgtgg
     2881 gcgtttttta ttttataaaa gtaatataca agacatgaca aatcgagcta tccaatttaa
     2941 aaagtaatgt tagtcaataa gattgaaaaa tgttataatg atgttcatga taatcattat
     3001 caattgggat gcctttgaaa attgataatt taaaaataga aattattttt tataaacaga
     3061 aagaatttta ttgaaagtag ggaaattatg aatcgtttgc atggacaaca agttaaaatt
     3121 ggttacgggg ataacacgat tataaataaa ttagatgttg aaataccaga tggcaaagtg
     3181 acgtcaatca ttggtcctaa cggctgcggg aaatctactt tgctaaaggc attgtcacgt
     3241 ttattggcag ttaaagaagg cgaagtattt ttagatggtg aaaatattca tacacaatct
     3301 acgaaagaga ttgcaaaaaa aatagccatt ttacctcaat cacctgaagt agcagatggc
     3361 ttaactgttg gggaattagt ttcatatggt cgttttccac atcaaaaagg atttggtaga
     3421 ttaactgctg aggataagaa agaaattgat tgggcaatgg aagttacagg aactgataca
     3481 ttccgacacc gttcaatcaa tgatttaagt ggtggtcaaa gacaacgtgt ttggattgca
     3541 atggcattag cacaaagaac tgatattatc tttttagacg aaccaacaac atatttagat
     3601 atctgtcatc aattagaaat actagaatta gttcagaagc taaatcagga acaaggttgt
     3661 acaattgtca tggttcttca tgatatcaac caagcgattc gtttctcaga tcatcttatt
     3721 gcgatgaaag aaggggatat catcgctaca ggttcaacag aagacgtatt aacacaggaa
     3781 atattagaaa aagtttttaa tattgatgtt gttttaagta aagatcctaa aactggaaaa
     3841 cctttactgg taacttatga cttatgtcgc agagcttatt cttaattaag taagttaata
     3901 tgataaaaag gacaattaac atgacaaata gagagaaccc aacgccattg aagtttttat
     3961 cctatattat aggtttaagt atgatactac taatcacact atttatttct acattaatag
     4021 gtgacgccaa aattcaagcc tctacaatta tagaggctat ttttaattat aatcctagca
     4081 atcaacagca aaacatcatc aatgagatta ggattcccag aaatatagca gcagtaattg
     4141 taggtatggc gcttgcagtt tctggtgcga ttatacaagg tgttactcgt aatggtcttg
     4201 ctgatccggc gctcataggt ttaaattcag gtgcttcatt tgctttagca ttaacatatg
     4261 cagttttacc aaacacttca tttttaatat tgatgtttgc tggattttta ggtgctattc
     4321 taggaggtgc tattgtatta atgataggcc gatctagacg tgatggattt aatccgatgc
     4381 gtattatttt agcgggtgca gcagtaagtg ctatgttaac agcgctaagt caaggtattg
     4441 cattagcttt tagactaaat caaacagtaa cattttggac tgctggaggc gtttcaggca
     4501 caacatggtc acaccttaag tgggcaattc cattaattgg tattgcgtta ttcattatat
     4561 taacaattag taaacaactt accattttaa atcttggtga atcattagct aaaggtttag
     4621 gtcaaaatgt aacaatgatc agaggcatat gtttaattat tgctatgatt ctagcaggta
     4681 ttgcagttgc tatcgctgga caagttgcat ttgtaggttt gatggtacct catatagcaa
     4741 gatttttaat tggaactgat tatgctaaaa ttctaccatt aacagccttg ttaggtggga
     4801 tactcgtgct tgttgccgat gtgatagcac gatatttagg agaagcgcct gttggtgcaa
     4861 tcatttcatt tatcggtgtt ccttactttt tatatttagt taaaaaagga ggacgctcaa
     4921 tatgattagt tcaaataata aacgcagaca attgatagca ctggctgttt ttagcattct
     4981 actatttcta ggttgtactt ggagtattac ctcaggtgaa tacaacatac ctgttgaaag
     5041 atttttcaaa actttaattg gacaaggtga tgccattgat gagttaatct tattagattt
     5101 caggttacct cggatgatga ttactatttt ggctggcgca gcgcttagta ttagtggtgc
     5161 aatagtgcaa agtgtcacaa aaaatccaat agctgaacca ggtatattag gtattaacgc
     5221 aggtggcgga tttgcaatcg cattatttat tgcaattggt aaaattaatg ctgacaactt
     5281 tgtttatgta ctgccgttaa taagtatact aggtggtatc accactgcat tgattatttt
     5341 tattttcagt tttaataaaa atgaaggtgt tacacctgcg agtatggtat taataggtgt
     5401 aggtttacaa acagcattat atggtggctc aattacaatt atgtcaaaat ttgatgataa
     5461 gcaatctgat ttcatcgctg cttggtttgc aggtaatatt tggggtgacg aatggccatt
     5521 tgtcattgca tttttaccgt gggtgttgat tattattcct tacttactat ttaaatcgaa
     5581 tacactaaat attattcata cgggtgataa tattgcacga ggtctaggtg taaggttaag
     5641 cagagaacgt ttaatattat tctttatcgc agtgatgtta tcatctgctg ctgtagcagt
     5701 agcaggttca atttcgttta tcggattaat gggtccgcat attgccaaac gtatcgttgg
     5761 accacgtcac cagttgtttt taccaattgc cattttagta ggggcatgtt tacttgttat
     5821 agctgataca attggcaaaa ttgtattaca accaggtggg gttccagcag gtattgtcgt
     5881 agcaattatt ggtgcaccgt atttcttata tttaatgtac aaaacgaaaa atgtatagtg
     5941 tcaaaggaca caacttattg ctatgaaagg cactttatta taaggctttt catagcattt
     6001 tttatttaat gagccactca agactattta ttttttcaat aatgaaccat taagttatca
     6061 agaggatctt atcaaaaata tatttgataa cggtatcagg ttaattcttt atgatagcgc
     6121 attcatttat tctgttttat actatgactg ataataccaa ggaggtacaa catgatgaaa
     6181 aagttaatca ataaaaaaga aacattttta actgatatgc ttgaaggatt gttaattgcg
     6241 cacccagagt tagatctgat tgctaataca gttattgtaa aaaaagctaa gaaagaacat
     6301 ggtgtagcaa tagtctctgg aggtggaagc ggacatgaac ctgcgcatgc cggttttgtt
     6361 gcagaaggta tgctagatgc agcggtttgt ggcgaagtat ttacatcacc tacacctgat
     6421 aaaatattag aagctattaa agcagtagat actggtgatg gtgtattact agttgtaaaa
     6481 aactatgcag gtgacgtgat gaatttcgaa atggcacaag agcttgcaga aatggaaggt
     6541 ataaatgttc aaactgttat tgttcgtgac gacattgctg tgacaaacga agtacaacgt
     6601 cgtggtgttg caggaacagt gtttgttcat aagcttgccg gttatcttgc tgaaaaaggt
     6661 tattcattaa cagagataaa atcgcgtgta gaagcgttgt tacctgaaat taaaagtatt
     6721 ggtatggcaa ttgagccacc gcttgttcca actactggaa aatatggctt tgatattgaa
     6781 gacgacaaaa tggaaatcgg tattggtata catggtgaaa aaggtattca tagggaagaa
     6841 gtaaaggata ttgatcatat tgttggaaca ttgttagacg aattgtataa agaagttact
     6901 gccaatgatg tcatattaat ggtaaatggt atgggtggta cgccgttatc tgaattaaat
     6961 atcgtaacta aatatattca acaaaattta gctgcaagaa cggttaatgt tgctaaatgg
     7021 tttgttggtg attatatgac atctttagac atgcaaggtt tttctataac tatcgtgcct
     7081 aataaaccag aatatttgga agcattttta gcaccaacaa caagtcaata ctttaaataa
     7141 gaagtgaata tgaataaata tacctttatg aggtggcaca aatgaaagtg aatgatatga
     7201 aagcacgttt attaaattta gaagaaacgt ttaaaaaaca tgaatctgaa ttaactgaat
     7261 tagatcgagc aattggtgat ggtgaccacg gggttaacat ggttcgtggg tttagtagtc
     7321 ttaaagacaa acttgatgat agctcaatgc aatcattgtt caaatcgact ggtatggcat
     7381 tgatgtcaaa tgttgggggt gcatcaggac cactgtatgg ctttagcttt gttaaaatgt
     7441 ctgcagtcac caaagatgat atggataatc aagatttcat tacactaatt aaggcatttg
     7501 ccgaagcggt tgaatcacgt ggtaaagtta ctttaaatga aaagacaatg tatgatgtag
     7561 tagcgcgagc agcagagaag cttgaaaatg gtgaaacttt aacattcaat gatttacagc
     7621 aattagcaga taatacaaaa gatatggtag caacgaaagg tagagctgca tattttggag
     7681 aagaatcaaa aggttatatt gatccaggtg ctcaaagtat ggtttatatt ttaaacgctt
     7741 tgattggaga tgaagataat gcctaaaatt atacttgtta gccacagtaa agaaattgca
     7801 agtggtacaa aatctttgtt aaagcaaatg gcaggtgacg ttgatattat accaatcggg
     7861 ggattaccag atggttcaat tggaacttca tttgatatca tccaagaagt tttgactaaa
     7921 ttagaggatg atgcattgtg tttttacgat attggatctt cagaaatgaa tgtagatatg
     7981 gcaattgaaa tgtatgatgg taatcatcgt gtgttaaaag ttgatgcacc aattgttgaa
     8041 ggcagtttta tcgcagcagt aaagctatca atcggcggtt caattgatga tgcattagca
     8101 gaaatcaaac aatcatttta gttaaaattt actaataatg aaaaatgtaa acctttttca
     8161 aatgaaactt tataaaaaat atgatagtat atatgtaaat gtttaataaa atctggagaa
     8221 ataggaggac attgccatgc aacaccttat aaaaaaacat gtattgaatg gcgagtttga
     8281 tttagtacga caattgatgt ccgaaacaga ttttatggaa tttgaagaag catatatttc
     8341 aagtgcgcat gaagtagaaa gtatgatgtt ttatacatgt attttagata tgattaagta
     8401 cgaagaatca tctgaaatgc atgacttagc atttttattg cttgtgtatc cactaagtga
     8461 atatgaaggt gctttggatt ctgcttatta tcatgcagac gcttccataa aacttactga
     8521 cggcaaagaa gttaaaagtt tgttacaaat gttattattg catgcgatac caacacctgt
     8581 tatttcagat aagaaggctt ttgatatcgc caagcaaatt ttaaaattag atcctaataa
     8641 taatgttgct cgtaacgtct taaaagacac tgccaaacgt atggacaacg ttgttgttga
     8701 tataaatgaa ttacaccaac gtaatgcacg ttaattacat ttcaattata ttagcttaat
     8761 aatagtttta acatttggtt gggttgggac atatgttcca gcctttttta atacttaaaa
     8821 actaacgaag tatacttgtg tgcacaaatg gtttttatac aacattttat aaatttatac
     8881 attttaataa agaacatacg atatatggtt taaaccttgt taactgagag attttgatat
     8941 gtattcttcg aaatttaact aaatttacga aattcaagaa gcacaataat taatcaattt
     9001 tcctatacaa aagttcgtat gactgcatta taaaagcata aatttataat ttttttaaat
     9061 gtcattgaac gtgataatgt gaatggattg agcaattttg aaaaagtgaa aaataaccta
     9121 tgcgacttgc aattaatttt cagtacgtta taatgcacac tgtgcaaaat taaggaggtc
     9181 tattattcac atgatgatga ataaagaagc aacaaaaatt ggatttgcct acgtcggcat
     9241 tgtagtgggc gcaggatttt caactggaca agaagttatg caatttttca ctaaatatgg
     9301 cttgtgggct tatttaggtg ttattatatc tggttttatt ttagctttta ttgggcgcca
     9361 agtagcaaaa attggtactg cctttgaagc gacaaaccat gaatcaacat tacaatacgt
     9421 attcggtgaa aagtttagta aagtctttga ttatatttta atcttcttct tatttggtat
     9481 agctgtaacc atgatagctg gtgcaggcgc aacatttgaa gaaagttata acatacctac
     9541 atggctaggt gctttaatta tgacattagc gatttatatt acgttgctat tagactttaa
     9601 taaaatagta cgtgcacttg gtatcgttac accattttta attgttttag ttgtattaat
     9661 cgctggcgtt tatttattta aaggtcatgt ttcattagca gaagttaacc aagtagtgcc
     9721 tgaagcaagt atttggaagg gaatctggtt tggtacaata tatggtggat tagctttttc
     9781 tgtaggtttt agtaccatcg tagcaatcgg tggggataca gaaaagcgta cagtgtcagg
     9841 tgcaggcgcg atgtatggtg gtattatcta tactgtatta ctagcattga tcaactttgc
     9901 attgcaaagt gaatatccaa ctattaaaaa tgcctcaatt ccaacattga cgttagcaaa
     9961 taatatccat cctttaatag caacagtgtt atctgttatt atgctggcgg ttatgtataa
    10021 tactattcta ggactaatgt attcatttgc agcacgtttt acagaaccat acagtaaaaa
    10081 ttatcatatc tttattatta taatgatggt agcaggttat ttattaagtt tcgtaggatt
    10141 tgctgaatta attaataagt tatatacaat tatgggatat gtaggcttat ttattgtagt
    10201 agctgtaatt attaaatatt tcaaacgtaa aaatgcggat aaaaaacata ttgcttaata
    10261 tcatatgatg gatatccgaa actttacaat tgaatcactt tgttttaacc ttaaaagcaa
    10321 ttcgtctcta ctcttatcgg gcgaattgct ttttatattt attcagtcta ttaatatgag
    10381 cgtctaacaa atagagaggt acgatgtaat gaataaagat aataaatgga cgatgataac
    10441 tgcgcttttt ataactgtaa tcagtgtatt gttagcattt catctgaaac aacattatga
    10501 ccaaattaca aatgagaacc atgctaataa agacaaaatt aatattaaaa ataaaaatgt
    10561 gcgcatttat caaaacctta catacaatag agttttccct aacagtaaat tagatattat
    10621 tacacctgtt gatatgtctt ctaatgccaa actgccagtt attttttgga tgcacggtgg
    10681 tggttatatt gcgggtgata agcagtataa aaacccatta ttagcgaaaa ttgctgaaca
    10741 agggtacatt gttgtgaatg taaattatgc attggcgcca caatataaat atcccacacc
    10801 attaattcaa atgaatcaag caactcaatt cattaaagaa aataaaatga atttacctat
    10861 tgattttaat caagtaatta ttggcggtga ttctgcaggt gctcaattag ctagccaatt
    10921 tacggcaata cagacgaatg atcgcttaag agaagccatg aaatttgatc agtcattcaa
    10981 accatcgcaa attaaaggtg ctatactatt tggtggtttt tataatatgc aaacagttag
    11041 agaaactgag tttccaagaa tacagttatt tatgaaaagt tatactggcg aagaagattg
    11101 ggaaaagagc tttaaaaata tttcacaaat gtcgacagta aaacaatcga caaaaaatta
    11161 tccaccaaca tttttatctg ttggagatag cgatccattc gaaagtcaaa atatagaatt
    11221 cagtaagaaa ttacaagaat tgaatgtacc agtagatact ttgttttatg atggtacgca
    11281 tcatttacat catcagtatc aatttcacct taataaacct gaatcgatag ataacatcaa
    11341 aaaagtgtta cttttcttaa gtcgtaatac atcttctagt ggtattcaaa ctgaagagaa
    11401 accacaaatg gaaaatccga gtaatgaatt accgttaaat cctttaaact aatgataaac
    11461 agtagtaatt tattacttaa gcaacattta agatcttcaa attgaaaacg aagaatttaa
    11521 aacatgtggg gctaatgtgt aagagtctga gatataataa attgttagcg gttctttatc
    11581 atttctatct caccctatta tgatgtgaca tttattttac aaactaattt gttttgaacc
    11641 tgaaaataac tttttacaac taaattgtcg aaaaacagtg tgtacatgat ataataaatt
    11701 tataaattga aaagaattca aaagaaaaaa taaaatatag attgagcacg aagtgatttg
    11761 aaataaggtt gtgaaaggga atgacaaggt cagcattaaa accatttaaa aataaacgcg
    11821 ttatggttac tggacgtata caacgtgttt tgtttaaaaa ttatttagat agacatagca
    11881 catttaagcc gaatgtaagg atattattaa aagatgtatt tgtttcaggt gtatcaatag
    11941 atcatttatg gttatatgag acaaataaat actatgcatt ggcaatggaa cttattcatc
    12001 aacgagtaaa atttagtgcg aatgttgtac catattacaa aataaataga aataataatt
    12061 tattcgtaca agattatgga attaagcgta aaggtaggtt aattactgaa gaagcttaca
    12121 atcaaaacaa tcagtatcag gataagatat atgaaaaatt accggatata gattttagac
    12181 tcgaagattt ttatagtaag gaaaactaaa caacatatat aaagcactac taatcgtagt
    12241 tgatagttga tcaattacac attagtggtg ctttattttg aatttaaatt tgataaatga
    12301 ataagagtat acgcattcat ttaagattag atgacattga taagtatgag taatgtatta
    12361 ggtaaccatt aaattcgttg ttatgcgatt ctgatacaag attatgataa aatagcttta
    12421 tttaagaatt ttagccatca tatagtcatc gtaatattta ccatcgataa ataacttatc
    12481 ttttaaaacg ccttcgattt gaaaatcggc acttttaaaa agctcgaggg caggttggtt
    12541 attgagtggt acatttgctt caattcggtg tatttgattg tttaaacacc aagccataat
    12601 ggcatcaaga agtgcttggc caattccacg atgttgatat aatttcttta cacctaaatc
    12661 aattttagca acatgtttaa tgcgttgaaa tggtgtcgta ttaacaaagg caaagccaac
    12721 gagttgttca tcactttcag caacaaagat gactttatgt ggagaagtga tatattcttc
    12781 taattgttta ctagccgacg tgacgctagg atcatattct cctggtgtgt agaacatata
    12841 cggagattcg tcgtatattt tcgctaacat tgaaatgaaa ttttctacat ctttgatact
    12901 aactctacgt ataatatggg ccataaaaag cctccagtat tttgaaattt taaaacattt
    12961 gctactatta taatatatat gtaactaaaa ggtggagtaa tatgtttttt ggttacagtt
    13021 taaaggagta ttttagatga aacctaaagt tttattagca ggtggaacag gatatattgg
    13081 taagtattta agtgaagtga ttgaaaatga tgctgaactt tttactatat caaaatatcc
    13141 agacaataaa aaaacagatg atgttgaaat gacttggatt cagtgtgata tatttcatta
    13201 cgaacaggtt gttgcagcaa tgaatcaaat agatattgct gtattcttta tcgacccaac
    13261 aaagaattct gccaaaataa cacaatcatc agcaagagat ttaacattaa tcgcagcaga
    13321 taattttggt cgagcagcgg ctatcaatca agtaaaaaaa gtaatctaca tacctgggag
    13381 tcgttatgat aatgaaacaa ttgaacgcct aggtgcatat ggcacacctg tagaaacaac
    13441 aaatttagtt tttaaacgtt ctttagttaa tgtagaatta caagtttcaa agtatgatga
    13501 tgttagatca acgatgaagg tagttttacc aaagggatgg acattaaaga acgttgtaaa
    13561 ccattttatt gcatggatgg gttacactaa aggaactttt gtgaaaacag aaaaatcaca
    13621 tgatcaattt aagatatata ttaagaataa ggtgcgaccg ctcgcagtat ttaaaataga
    13681 agaaacagct gacggaataa taactttaat tttattgagt ggaagtttag tgaaaaaata
    13741 cacagttaat caagggaagt tagaatttag attaatcaaa gagtcggcag tcgtttatat
    13801 acatctatac gattatatcc ctcgattatt ttggccgatt tattacttta tacaagcacc
    13861 aatgcaaaaa atgatgattc atggctttga agttgactgc cggattaaag attttcaaag
    13921 tcgattaaaa tcaggagaaa atatgaaata tactaaatga tattgggtga tatggatgca
    13981 aatactacta gtagaagatg acaatacttt gtttcaagaa ttgaaaaaag aattagaaca
    14041 atgggatttt aatgttgctg gtattgaaga tttcggcaaa gtaatggata catttgaaag
    14101 ttttaatcct gaaattgtta tattggatgt tcaattacct aaatatgatg ggttttattg
    14161 gtgcagaaaa atgagagaag tttccaacgt accaatatta tttttatcat ctcgtgataa
    14221 tccaatggat caagtgatga gtatggaact tggcgcagat gattatatgc aaaaaccttt
    14281 ctataccaat gtattaattg ctaaattaca agcgatttat cgtcgtgtct atgagtttac
    14341 agctgaagaa aaacgtacat tgacttggca agatgctgtc gttgatctat caaaagatag
    14401 tatacaaaaa ggtgacgata cgatttttct atccaaaaca gaaatgatta tattagaaat
    14461 tcttattacc aaaaaaaatc aaatcgtttc gagagataca attatcactg cattatggga
    14521 tgatgaagca tttgttagtg ataatacgtt aacagtaaat gtgaatcgtt tacgaaaaaa
    14581 attatctgaa attagtatgg atagtgcaat cgaaacaaaa gtaggaaaag gatatatggc
    14641 tcatgaataa tttgaaatgg gtagcttatt ttttgaaatc tcgcatgaac tggatatttt
    14701 ggatattgtt tttaaacttg cttatgttag gcattagtct aatcgattat gattttccaa
    14761 tagacagttt attttatatt gtttctttga atttaagttt aacaatgatt tttcttatat
    14821 tgacatattt taaagaagta aaattatata agcattttga caaagataaa gaaatagaag
    14881 aaattaaaca taaagattta gcggaaacgc catttcaacg tcatacagtt gattatttat
    14941 atcgtcaaat ctcagcgcac aaagaaaagg ttgttgagca acagttacaa ttgaacatgc
    15001 atgaacaaac cattacagaa tttgtgcacg acataaaaac acctgtgaca gccatgaaat
    15061 tattaattga tcaagaaaaa aatcaagaaa gaaaacaggc attactatat gaatggtctc
    15121 gtataaactc gatgctggat acacagctgt atattactag attagaatct caacgcaaag
    15181 atatgtattt tgattacgtg tcacttaaac gcatggtcat tgatgaaata caattaacaa
    15241 gacatattag tcaggttaaa ggtattggtt ttgatgttga ctttaaagtg gatgattatg
    15301 tttatacaga tacaaaatgg tgtcgtatga ttattagaca gattttgtca aacgcattga
    15361 aatatagtga gaattttaat attgaaattg ggacagaatt aaatgatcaa catgtttcgt
    15421 tatatattaa agactatggc agaggtatta gtaaaaaaga tatgccgcga atatttgaac
    15481 gaggatttac gtcaacggct aacagaaatg aaacgacgtc ttcaggtatg ggtctatatt
    15541 tagtaaatag tgtaaaggat caattaggta ttcacctgca agtcacgtcg actgttggta
    15601 aggggacaac tgtcagattg attttcccat tacaaaatga aattgttgaa cgcatgtcgg
    15661 aagtgacaaa tttgtcattt taaacatgcg ttttgttact tagaattgat acatcaatgc
    15721 agcttcaacg ttataataag atagatgtta gtcatatgtt aaattgaaga tacaagtgcc
    15781 aaagcctaaa ggaaatgaag ttaagataaa ttataggagt gttaaagtgg caattttaga
    15841 agtaaaacaa ttaacaaaaa tatatggaac taaaaaaatg gcacaagaag tgttgcgaga
    15901 tatcaatatg tctattgaag aaggcgagtt tattgctatt atgggtccct ctggatctgg
    15961 gaaaacgaca ttattaaatg ttttaagttc aattgattat atttcacaag gttctattac
    16021 attaaaagga aaaaaattag aaaagctttc aaacaaggaa ttatctgata tacgcaagca
    16081 tgatattggt tttatttttc aagagtataa tttactgcat acattgactg ttaaagaaaa
    16141 cataatgtta ccactaacgg ttcagaagtt agataaagaa catatgttaa atcgttatga
    16201 aaaagtagca gaagcattaa atatattgga tattagtgat aaataccctt ctgaattgtc
    16261 tggtggacaa agacaacgaa catctgctgc aagagcgttt attacattac cttctattat
    16321 atttgctgac gaaccaacag gtgcactgga ttctaaaagt actcaagatt tattaaaacg
    16381 attaacaaga atgaatgaag catttaagtc tacaattatt atggtaacgc atgatcctgt
    16441 tgcagcaagt tatgccaatc gagtagtgat gctaaaagat ggtcaaattt tcactgaatt
    16501 ataccaaggg gatgacgata aacatacctt tttcaaagaa ataatacgtg tacaaagtgt
    16561 tttaggtggc gttaattatg acctttaacg agataatatt taaaaatttc cgtcaaaatt
    16621 tatcacatta tgccatctat cttttttcat taattacgag tgtagtattg tattttagct
    16681 ttgtagcatt aaaatacgcg cataaactaa acatgacaga gtcatatcca attattaagg
    16741 aaggctcaca agtcggaagc tactttctat ttttcatcat aattgcattt ttgttatatg
    16801 ccaatgtgtt atttattaaa cgacgaagtt atgagcttgc attatatcaa acattaggtt
    16861 tatctaaatt caacattatt tatatactaa tgctcgaaca attactaata tttataatta
    16921 cggcaatatt aggtattatt attggtattt ttggttcaaa actgttatta atgattgtct
    16981 ttacattatt aggaattaaa gaaaaggttc caattatttt tagtttgagg gcggtatttg
    17041 aaacattaat gttaatcggt gtcgcttatt ttttaacctc tgctcaaaat tttatattag
    17101 tgttcaaaca atctatttca cagatgtcaa agaataacca ggttaaagaa acaaatcata
    17161 ataaaattac atttgaagag gttgttttag gcatcttagg tatagtattg attaccacag
    17221 gatactatct atctttgaac attgttcaat attatgattc tatcggtata cttatgttta
    17281 ttttattgtc aactgtgatt ggggcatact tattttttaa aagctctgtt tctctagttt
    17341 ttaaaatggt gaagaagttt agaaaaggtg ttataagtgt aaatgatgtc atgttctcat
    17401 catctattat gtatcgtatt aagaaaaatg ctttttcact tacggtcatg gcaatcattt
    17461 cagcgattac tgtttcagtt ctttgctttg ctgctataag tagagcgtcc ttatcaagtg
    17521 aaataaaata tactgcacca cacgacgtta caattaaaga ccaacaaaaa gctaatcaat
    17581 tagcaagtga attaaacaat caaaaaattc ctcattttta taattataaa gaagtaattc
    17641 atacgaaatt gtataaagat aatttatttg atgtaaaagc gaaagaacca tacaatgtaa
    17701 caattactag tgataaatat atccctaata ctgatttgaa acgtggacaa gctgatttgt
    17761 ttgtagcgga aggttctatc aaagatttag tgaaacataa gaagcatggt aaggcaatta
    17821 taggaacgaa aaaacatcat gttaatatta agttacggaa agatattaat aaaatctatt
    17881 ttatgacaga tgttgattta ggtggaccaa cgtttgtctt aaatgacaaa gactatcaag
    17941 aaataagaaa gtatacaaaa gcaaagcata tcgtctctca atttggattc gatttgaaac
    18001 ataaaaaaga tgctttagca ttagaaaaag tgaaaaataa agttgataaa tctattaaaa
    18061 caagaagtga agcgataagc tcaatatcaa gtttaaccgg aatattatta tttgtaacat
    18121 catttttagg tattacattc ttgattgctg tatgttgcat tatatacatt aagcaaatag
    18181 atgaaaccga agatgagtta gagaattata gtatattgag aaagcttgga tttacacaaa
    18241 aagatatggc aaggggacta aagtttaaaa ttatgtttaa ttttgggtta cctttagtta
    18301 ttgcactatc acatgcatat tttacatcat tagcatatat gaaattaatg ggtacaacga
    18361 atcaaatacc ggttttcata gtaatgggat tatacatttg tatgtatgct gtttttgcag
    18421 tgacggctta taatcattcc aagcgaacaa ttagacattc catataaaat atacagatgg
    18481 ctttcagtag agtagtggat tcgaattcac gaactatact ggaagctttt tattataaat
    18541 gaagagaagt tatattttta gcatgtatag ttgaatactg ggttaaaata ccatattaat
    18601 aatgaagtaa aggtatgagt gattatgaaa gtgttttgaa tgaaatatat ttaattggtg
    18661 atgcttttaa ttgaaaagat taacaggatt caactttgta aattgtatta aatgtgagaa
    18721 aataaaagta tattcattga gatatatatg agtcaatgat cgttttaaac aagataagtg
    18781 tattttaata tgtaaaagtt atgtaataaa tattgtatcg ttgcaaattt cccaactata
    18841 tccatttaca atttttagag ttgtatagat aaaaaaatgc ctataaaata actttttcaa
    18901 aacaaatgcc tactactatt taaattttat gtaaaagtta agtttcggaa ttgttaaaaa
    18961 tttgtaaatt gaattgtggg attgtaaatt ttgtgctatt ttcatataag ggcaaataca
    19021 gtaaattgtt tactgtgagg catttttgaa attaatatca gtacactaaa attatactga
    19081 cgattgataa taacaaattt gtatcattag tttgtaaatt cacttgtctt aatttgaaac
    19141 aaattataac tgaatgtgat tggtgacaat cgcttaaatg gaggatttta aatgtttagt
    19201 aagaaaaaag ataagtttat ggttcaatta gaagagatgg ttttcaatct ggatcgtgct
    19261 gctattgaat tcggtaaaat ggatttcaat acacatttag atttaaaagc atactcagac
    19321 aacattaaaa cttatgagtc acatggtgac gaattagtac atcaagtaat tactgattta
    19381 aatcaaacat ttatcacacc aattgaacgt gaagatattt tatcattatg tgatgcaatt
    19441 gatgatgttt tagatgcaat tgaagaaacg gcagctatgt ttgaaatgta ttcaatcgaa
    19501 tacacagatg aatatatggc tgagtttgtt gataacattc aaaaagcagt tgcagaaatg
    19561 aaacttgctg tcggcttatt agtcgataaa aaattatcac atatgcgtat tcattcaatt
    19621 aatattaaag aatttgaaac aaactgtgat ggtattttaa gacagtcaat taaacatatt
    19681 ttcaatagcg aaacagatcc aatcacatta attaaaataa aagatattta tgaaagcatg
    19741 gaagaaattg ctgataaatg tcaaatcgta gcaaataatt ttgaaactat tattatgaaa
    19801 aatagctaag gggagtatat atttatgtca tatataatca tcgtcactat agctgtagtt
    19861 attttctcgc tgatatttga ctttatcaat ggattccatg atacagccaa tgcagtagct
    19921 actgctgtat ctactagagc gttaacgcct aaaacggcaa ttttaatggc agcagtgatg
    19981 aactttatag gtgctttaac atttacgggc gttgcaggca ccattactaa agacattgtc
    20041 gatccattta aattggaaaa tggattagtt gttgtgttag ctgcaatact tgcggctatt
    20101 atttggaatt tagctacttg gttttacgga attccaagtt cgtcttcaca tgcacttata
    20161 ggttcaattg cgggtgcagc aatcgcatct gaaggctcat ttggagtgtt acattaccaa
    20221 ggtttcacaa aaattattat tgtattaatc gtttcaccga taatcgcatt ttgtgttggt
    20281 ttcttgatgt attcaatttt taaagttatc tttaaaaatg caaatttaac aagagcgaat
    20341 cgtaacttta gatttttcca aattttcacg gcagcgttac aatcattctc tcacggtacg
    20401 aatgatgcgc aaaaatcaat gggtattatt acgttggcat tgattgtcgc taatgtacag
    20461 aatgatggca gtgttgaacc acagttatgg gtaaaatttg cctgtgcgac agcaatgggg
    20521 cttggtactg caattggtgg ctggaaaatt atcaaaactg taggtggtaa tattatgaaa
    20581 atacgtccag caaatggtgc tgcggccgat ttatcatctg cattaacaat ttttgttgca
    20641 tcatcgctac atttcccatt atcaacaact cacgttgtgt catcatcaat cttaggtgtt
    20701 ggtgcttcta accgagctaa aggtgtaaaa tggagcactg cgcaacgaat gatcattaca
    20761 tgggtgatta cattacctat ttcagcattg ttagcaggtt tactattcta tatacttaac
    20821 ttatttttct aattgaaaat aaaactaaac tgaacttcag tatcacaaac atatggtggt
    20881 attgaagttc atttttttat gtaagtagat aacatatttt atagaattta cgtagaatga
    20941 ccaagacaaa gcattttaat tagggggcta agttataaat ttattccatg gaacataaac
    21001 agttaggtca ttaaaatata agtaagcgta aaataatgat ttaatagttt atattcttca
    21061 atgaaggaat aattaaatag ttatcaactt gtttaattaa cctaaattgt attgggcttt
    21121 atttaatata aatttgtata tgtagaagaa aa
//
LOCUS       DAPDIM010000049        21122 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000049 DAPDIM010000000
VERSION     DAPDIM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21122
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.049"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            86..622
                     /gene="amaP"
                     /locus_tag="RFE25_001957"
     CDS             86..622
                     /gene="amaP"
                     /locus_tag="RFE25_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDU2817003.1"
                     /translation="MKRLKNFILGLLIVVIVGFLLFMYIQDGRITEYQDYFLQFEWFQ
                     PLLISLAALLILIGFILVFSIFKPTHRKPGLYKDFDDGHVYVSRKAVEKTAFDTVAKY
                     DQVRQPNVVAKLYNKKNKSYIDIKTDFFVPNNVQVQSLTEAIRSDIKKNVEYFTEMPV
                     RKLEVNVRDQKTSGPRVL"
     gene            635..874
                     /locus_tag="RFE25_001958"
     CDS             635..874
                     /locus_tag="RFE25_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDU2817004.1"
                     /translation="MANNHNQNGQDSTQQVINFLKVFKWRIVGFLAFLLIAILFLTLG
                     FWKTVLIIVLCLIGVGIGYMKDRKQDFMNFLNRWS"
     gene            937..1446
                     /locus_tag="RFE25_001959"
     CDS             937..1446
                     /locus_tag="RFE25_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDU2817005.1"
                     /translation="MTVDNNKAKQAYDNQTGVNEKEREERQKQQEQNQEPQFKNKLTF
                     SDEVVEKIAGIAAREVKGILDMKGGLTDTFTNAFSSGNNVTQGVSVEVGEKQAAVDLK
                     VILEYGESAPKIFRKVTELVKEQVKYITGLDVVEVNMQVDDVMTQKEWKQKHEKNNEN
                     NNQERQGLQ"
     gene            complement(1607..3583)
                     /gene="sfaD"
                     /locus_tag="RFE25_001960"
                     /gene_synonym="sfnaD"
     CDS             complement(1607..3583)
                     /gene="sfaD"
                     /locus_tag="RFE25_001960"
                     /gene_synonym="sfnaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ornithine--citrate ligase SfaD"
                     /protein_id="HDU2817006.1"
                     /translation="MNLNLIFKEQTLKFNKEEQETYLFLQQHNSDWANIFKEMILQGR
                     DKVTQRLVTSMHRENLVKARTQSKKILSRDLIMLDISTTHILEIQFPQAKQTLYAPIT
                     GEHAFDRIDVEGPFYIKDDITNTITRVHHPNEILECILIEAPDLKNAASDQFQQDLIN
                     SATNMTFAISYQALSMQHDSAPLFNIIENSEDSYLRSEQAVIEGHPLHPGAKLRKGLN
                     ALQTFLYSSEFNQPIKLKIVLIHSKLSRTMSLSKDYDTTVHQLFPDLIKQLENEFTPN
                     FNFNDYHIMIVHPWQLDDVLHSDYQAEVDKELIIEAKHTLDYYAGLSFRTLVPKYPAM
                     SPHIKLSTNVHITGEIRTLSEQTTHNGPLMTRILNDILEKDVIFKSYASTIIDEVAGI
                     HFYNEQDEVDYQTERSEQLGTLFRKNIYQMIPQEVTPMIPSSLVATYPFNNESPIVTL
                     IKRYQSAASLSDFESSAKSWIETYSKALLGLVIPLVTKYGIALEAHLQNAIATFRKDG
                     LLDTMYIRDFEGLRIDKAQLNEMGYSTSHFHEKSRILTDSKTSVFNKAFYSTVQNHLG
                     ELILTISKASNDSNLERHMWYIVRDVLDNIFDQLVLSTHKSNQVNENRINEIKDTMFA
                     PFIDYKCVTTMRLEDEAHHYTYIKVNNPLYRENN"
     gene            3685..4878
                     /gene="sfaA"
                     /locus_tag="RFE25_001961"
     CDS             3685..4878
                     /gene="sfaA"
                     /locus_tag="RFE25_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin A export MFS transporter"
                     /protein_id="HDU2817007.1"
                     /translation="MTKYFFSSSFLLFLGNWIGQIGLNWFVLTTYHNAVYLGIVNFCR
                     LVPILLLSVWAGAIADKYDKGRLLRITISSSFLVTAILCVLTYSFTAIPISVIIIYAT
                     LRGILSAVETPLRQAILPDLSDKISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAP
                     TTFLAQAICYFIAALLCLPLHFKVTKIPEDATRYMPLKVIIDYFKLHMEGRQIFITSL
                     LIMATGFSYTTLLPVLTNKVFPGKSEIFGIAMTMCAIGGIIATLVLPKVLKYIGMVNM
                     YYLSSLLFGIALLGVVFHNIVIMFICITLIGLFSQWARTTNRVYFQNNVKDYERGKVL
                     SIIMMDRGMIPLGSLLMSICADVFGIVRTFSIMGISTICITMVFYFINRKLKLKLEES
                     NHGIS"
     gene            4865..6622
                     /gene="sfaB"
                     /locus_tag="RFE25_001962"
     CDS             4865..6622
                     /gene="sfaB"
                     /locus_tag="RFE25_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin A synthetase SfaB"
                     /protein_id="HDU2817008.1"
                     /translation="MVYLEWAKADRNIQYRVINAIIKERIYPEQTFISQKGSLIEIQY
                     HMHVLTIEVVRKSALERYEFTGDITYLNKGETSLIITLEGLLDVLNHDFDIPISERLR
                     EELIHSRDSLVETYKQMSHRQTLISQSFKFSRLPQDINFFSWLQHVKDSDKTDDLTYS
                     ESLVPEGHPTHPLTKTKLPLTMEEVRAYAPEFEKEIPLQIMMIEKDHVVCTAMDGNDQ
                     FIIDEIIPEYYNQIRVFLKSLGLKSEDYRAILVHPWQYDHTIGKYFEAWIAKKILIPT
                     PFTILSKATLSFRTMSLIDKPYHVKLPVDAQATSAVRTVSTVTTVDGPKLSYALQNML
                     NQYPGFKVAMEPFGEYANVDKDRARQLACIIRQKPEIDGKGATVVSASLVNKNPIDQK
                     VIVDSYLEWLNQGITKESITTFIERYAQALIPPLIAFIQNYGIALEAHMQNTVVNLGP
                     HFDIQFLVRDLGGSRIDLETLQHRVSDIKITNDSLIADSIDAVIAKFQHAVIQNQMAE
                     LIHHFNQYDCVEETELFNIVQQVVAHAINPTLPHANELKDILFGPTITVKALLNMRME
                     NKVKQYLNIELDNPIKKEV"
     gene            6629..7699
                     /gene="sfaC"
                     /locus_tag="RFE25_001963"
     CDS             6629..7699
                     /gene="sfaC"
                     /locus_tag="RFE25_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin A biosynthesis protein SfaC"
                     /protein_id="HDU2817009.1"
                     /translation="MAHVNINISKIKYNAKVLQTVFQSKNIQFTPVIKCIAGDRTIVE
                     SLKALGINHVAESRLDNIISIADQDLTYTLLRTPAKKEISDMIEKVDMSIQTELSTIH
                     QINEVAEVLGKKHKILLMVDWKDGREGVLTYDVLDYIKEIIHLKNIHFVGLAFNFMCF
                     KSDAPSDDDIFMINRFVSAVEREIGYRLKIISGGNSSMLPQLLYNDLGKINELRIGET
                     LFRGVDTTTNQAIAMLYQDAITLEAEILEIKPRVNTQTHESFLQAIVDIGYLDTKVDN
                     ISPMDQHINILGASSDHLMLDLNGQGHYQVGDHISFSLNYEALSHSMYMKNLHKVYID
                     DSKIDTLLQNFDVKSPAMVNQY"
     gene            complement(7800..7925)
                     /locus_tag="RFE25_001964"
     CDS             complement(7800..7925)
                     /locus_tag="RFE25_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817010.1"
                     /translation="MYHCYIIFALIQLTPFSMTVIPVIQLILSVAILCDELLHLI"
     gene            8091..9074
                     /locus_tag="RFE25_001965"
     CDS             8091..9074
                     /locus_tag="RFE25_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDU2817011.1"
                     /translation="MRGLKTFSILGLIVALLLVAACGNTDNSSKKESSTKDTISVKDE
                     NGTVKVPKDAKRIVVLEYSFADALAALDVKPVGIADDGKKKRIIKPVREKIGDYTSVG
                     TRKQPNLEEISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTI
                     AKALNKEKEGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQF
                     LNELGFKNALSDDVTKGLSKYLKGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKK
                     LQEDATWKKLNAVKNNRVDIVDRDVWARSRGLISSEEMAKELVELSKKEQK"
     gene            9086..10117
                     /locus_tag="RFE25_001966"
     CDS             9086..10117
                     /locus_tag="RFE25_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDU2817012.1"
                     /translation="MAIKEISSQSAIDHKRKRRTTLTYIVSLCFLFICIYLNMAIGSS
                     KINFSDIIHYVTGHTDTKATFLLHNVRMPRMIAGLFIGGALAVSGLLMQAMTRNPLAS
                     PKIFGVSSGASFFIVFVTIIIPSLEYYALYLGVIGAFIGGLTVYTLSGATKGMTPIKL
                     ALAGMAIHLFFSSMTEGIIILNENSNEQVMFWLVGSLSSMKWDEILTILPWIIGALIV
                     TIFIGRQLTIMELGDDIAKGLGQNINKVRIIIGLLVIILTGMSVSVAGPIGFVGLIVP
                     HIVKRYVSKNYLVMIPLTFIIGADLLLLSDVLSRLITYPYESPVGIVTSFVGALYFLF
                     ITIKGVKRI"
     gene            10114..11082
                     /locus_tag="RFE25_001967"
     CDS             10114..11082
                     /locus_tag="RFE25_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDU2817013.1"
                     /translation="MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFTQ
                     DDFILNEYRIPRTLLGIIIGSSLAISGAIIQAVIRNPLASPDVIGISKGASLAAVIII
                     MIFPTAPLFVLPIGSFLGAFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFL
                     LIRNPLEANKALVWLTGSLYGHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVA
                     TALGLKVKTIKMLLLILAVILAGSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMS
                     GLIGAILLTFGDGLARGIHPPLDIPVGVIIAIIGAPYFLILLRRMK"
     gene            11318..12688
                     /locus_tag="RFE25_001968"
     CDS             11318..12688
                     /locus_tag="RFE25_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiH family protein"
                     /protein_id="HDU2817014.1"
                     /translation="MDSFSRKEIVIGRLKFITMSLIGILLFLVPIPVEQDGQKQTTLP
                     VAFLAGVLKDVLGGVMPFLIVTIITLSGIITLICSTILKDKLKPDGLMNNAFNVRIGW
                     LILRILAVVFAWMTFLRIGSKVIYSDETGGLLFSSLLPTLVAVFLFAALFLPLLMEYG
                     LLEMLGPIFRPVMRPLFTLPGRSTVDNLASFIGDGTVGVLITSRQYGEGYYSRREATV
                     ISTTFSVVSITFAIVVAETVHMQNQFFAFYLSVIVSCLVAAVIMPRIWPLNKIPDEYA
                     KEVPESARTEALPEGKTALRHGFDTATEVGIKAPGVIDFFKSGLKTVIDMWFVILPVV
                     MSIGTIATIIANYTPFFVILGKPFVPFLELMQIPEAAQASQTIIIGFADMFLPSILIE
                     GVQNDITRFVIGALSISQLIYLSEVGGVILGSKIPVSIGKLFMIFLIRTIITLPIISL
                     MAHLLL"
     gene            complement(12820..13080)
                     /locus_tag="RFE25_001969"
     CDS             complement(12820..13080)
                     /locus_tag="RFE25_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817015.1"
                     /translation="MAMTVKKDNNEVRIQWRVADIKIPTSEIKNITQDQDIHAVPKLD
                     SKDVSRIGSTFGKTNRVIIDTEDHEYIIYTQNDQKVYNELTK"
     gene            13257..13772
                     /locus_tag="RFE25_001970"
     CDS             13257..13772
                     /locus_tag="RFE25_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDU2817016.1"
                     /translation="MTGKTHASCGMLVGALTTQYFQTDIFSSVTVIILATLASLLPDI
                     CHTQSKIGRRFKVISFFVRLIFGHRTFTHSILFIAIIAFLLQIIQTPNYYMAAIIIGL
                     VSHVILDMITPRGVKLFYPLPFNVKTPIQFKTGGLVDLSLATALMVGTVYVLFQPFIN
                     DIISNWNTKFL"
     gene            13816..15003
                     /locus_tag="RFE25_001971"
     CDS             13816..15003
                     /locus_tag="RFE25_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDPGP type 1 family protein"
                     /protein_id="HDU2817017.1"
                     /translation="MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAK
                     LYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGG
                     QGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYF
                     EAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYL
                     EEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNV
                     DCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDEN
                     FGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRM
                     GLI"
     gene            15022..15705
                     /locus_tag="RFE25_001972"
     CDS             15022..15705
                     /locus_tag="RFE25_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDU2817018.1"
                     /translation="MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLV
                     LPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMI
                     YVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMG
                     WVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLL
                     HLIAILYFM"
     gene            15882..17225
                     /locus_tag="RFE25_001973"
     CDS             15882..17225
                     /locus_tag="RFE25_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDU2817019.1"
                     /translation="MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLIS
                     LIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRV
                     IQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWH
                     WLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQL
                     LLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNL
                     YIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVS
                     SIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNL
                     GASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE"
     gene            17324..17797
                     /gene="sepA"
                     /locus_tag="RFE25_001974"
     CDS             17324..17797
                     /gene="sepA"
                     /locus_tag="RFE25_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter SepA"
                     /protein_id="HDU2817020.1"
                     /translation="MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRI
                     LIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATF
                     HLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK"
     gene            18120..19563
                     /gene="lmrS"
                     /locus_tag="RFE25_001975"
                     /pseudo
     CDS             18120..19563
                     /gene="lmrS"
                     /locus_tag="RFE25_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500890.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter LmrS"
     gene            19711..20775
                     /locus_tag="RFE25_001976"
     CDS             19711..20775
                     /locus_tag="RFE25_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-loop NTPase"
                     /protein_id="HDU2817021.1"
                     /translation="MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVK
                     LAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEG
                     LLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGI
                     DEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIE
                     YLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVI
                     ENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSD
                     DRLGKIYSSIAQKVIAATNK"
     gene            20864..21048
                     /locus_tag="RFE25_001977"
                     /pseudo
     CDS             20864..21048
                     /locus_tag="RFE25_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500888.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         7077 a         2854 c         3859 g         7332 t
ORIGIN      
        1 aatttattat gtttaagaaa aaaactgatg ggtacatatt taatatgttt ttaaattaac
       61 tttaactaag gaggtgtcgt taggggtgaa acgacttaaa aactttatcc ttggcttatt
      121 aatagtagta atcgtggggt tcctgttatt catgtatatc caagatggac gtataactga
      181 atatcaagac tacttccttc aatttgaatg gttccaacca ttacttattt cacttgctgc
      241 actattgata ttaataggtt ttatattagt atttagtatc ttcaaaccta cgcatcgaaa
      301 acctggatta tacaaagact tcgatgatgg tcatgtttac gtatctcgta aagctgttga
      361 aaagacggca ttcgatacgg ttgcaaaata tgatcaagta agacaaccaa atgtagttgc
      421 gaaactatat aacaaaaaaa ataaatctta tatcgacatt aaaactgact ttttcgtacc
      481 aaataatgtt caagttcaat ctttaactga agcaattcgt tcggatatta aaaagaatgt
      541 agaatatttc acagaaatgc cagtacgtaa gttagaagtt aatgtgagag atcagaaaac
      601 ttctggtcca cgagtgttgt aagggaggta tatcatggct aacaatcata accaaaacgg
      661 acaagactct acacaacaag tgattaattt tttaaaagta tttaaatgga gaatcgttgg
      721 tttcctagcg tttctattaa tcgcgatatt attcttaacg ttaggttttt ggaaaacagt
      781 acttatcatc gttttatgtt taattggtgt aggtattggg tatatgaaag accgtaagca
      841 agattttatg aattttttaa atcgatggag ttaattcatc aatttagaat ttaattaaaa
      901 aaatataaaa attaacaagt aaaaggagaa tctattatga ctgtagataa caataaagca
      961 aaacaagcat acgacaatca aactggtgtt aacgaaaaag aaagagaaga gcgtcaaaaa
     1021 caacaagaac aaaatcaaga gcctcaattc aaaaataaat taactttctc tgatgaagtt
     1081 gttgaaaaaa ttgctggtat cgctgcacgt gaagttaaag gtatcttaga catgaaaggt
     1141 ggcttaactg atacattcac taatgcattc tcaagtggaa ataacgttac tcaaggtgta
     1201 tctgttgaag ttggtgaaaa acaagctgct gtagacttaa aagtaatttt agaatatggt
     1261 gaatcagcac caaaaatctt ccgtaaagta actgaattag ttaaagaaca agttaaatat
     1321 attactggtt tagatgttgt tgaagttaac atgcaagttg atgatgtaat gactcaaaaa
     1381 gaatggaaac aaaaacacga aaaaaataat gaaaacaata accaagaaag acaaggttta
     1441 caataagtta ttcgataaaa aagctcggca caccatttta gtgccgagct tttttgtgat
     1501 ttttaataat ttgaatatgg aaaatgtatt attctctcat ttgtatagat tgtatttaat
     1561 aagttaatgt aatccttgag ctcacgatta ataaaattct ataattttaa ttattttctc
     1621 gatacaaagg attattaact ttaatataag tataatgatg tgcctcatct tcaagacgca
     1681 ttgttgtaac acacttataa tctataaatg gcgcgaacat ggtatcttta atttcattta
     1741 tgcgattctc atttacttga ttagatttgt gtgtcgaaag tacaagttga tcaaaaatgt
     1801 tatctagtac atcacgaacg atataccaca tatgtctttc taagtttgaa tcatttgatg
     1861 ctttagagat tgtaagaatt aattcgccta aatggttttg aacggtagaa taaaaggctt
     1921 tgttaaacac agacgttttt gaatcagtaa gaattcttga tttttcatgg aaatgagatg
     1981 tactgtatcc catttcattt agttgtgctt tatcaattct taaaccttca aagtctctaa
     2041 tatacatcgt gtccaataga ccatctttcc gaaatgttgc aatagcattt tgcaagtgag
     2101 cctctaatgc aatgccatat ttagtaacta gtgggattac gagaccaagc aatgctttac
     2161 tataagtttc aatccacgat ttcgccgatg attcaaaatc agacaatgat gcagctgatt
     2221 gataacgttt aatcaatgtc acgataggtg attcattgtt aaatgggtag gttgcaacta
     2281 agcttgaagg aatcattggt gtgacttctt gtggaatcat ttggtatatg ttttttctaa
     2341 ataatgtacc taattgttca cttcgttcag tttgatagtc tacttcgtct tgctcattat
     2401 aaaaatgaat accagcaact tcatcaataa ttgttgatgc ataggactta aatatgacat
     2461 ctttctccaa aatatcattt aaaatacgtg tcattagtgg accattgtgc gtcgtttgtt
     2521 ctgataatgt acgaatttca cctgtaatat gaacgtttgt cgacaatttg atgtgtggcg
     2581 acatagctgg gtatttagga actaatgttc tgaaagataa accggcataa taatccaacg
     2641 tatgttttgc ttcaatgatt aattctttat ctacttctgc ttgataatca gaatgtaata
     2701 cgtcatctaa ttgccatgga tgtacaatca taatgtgata atcattaaag ttaaagtttg
     2761 gcgtaaattc attttctaat tgtttaatta agtccggaaa tagctgatga acagttgtat
     2821 cataatcttt agacagtgac atagtacgac ttaatttact gtgaatcagt actattttca
     2881 acttaatagg ttgattaaat tctgaagaat ataggaatgt ttgtaatgca tttaaacctt
     2941 tacgtaattt agccccagga tgtagcggat gaccttcaat aacggcttgc tctgaacgca
     3001 agtaactatc ttcgctattt tcgataatat taaataaagg tgcagaatca tgttgcattg
     3061 acagtgcttg atagctaatt gcaaatgtca tattagttgc actgtttatt aaatcttgct
     3121 gaaattgatc actagcagca ttttttaaat ctggtgcttc aattaaaata cactcaagaa
     3181 tttcatttgg atggtgtact cgtgtaatcg tatttgtaat gtcatcttta atgtagaaag
     3241 ggccttcaac atcaattcga tcaaaggcgt gttctccagt gataggagca tataatgttt
     3301 gcttagcttg tgggaactgg atttctagta tatgagtcgt tgagatatct aacataatca
     3361 aatcacgact caatattttc ttactttgag tgcgcgcttt aactaagttt tcgcgatgca
     3421 ttgatgtgac taatctctga gtgactttat ctcttccttg taaaatcatc tctttaaaaa
     3481 tattagccca atcgctatta tgttgttgta aaaataaata tgtttcttgt tcttctttgt
     3541 taaattttaa tgtctgttct ttaaaaatta agttcaagtt cataattcac ctctatgaaa
     3601 tattttacaa aagcaagata gatttgtata atccatatta atgataatga ttcttattat
     3661 caacagaatg cgggtgtaag ttttatgaca aaatattttt ttagcagttc ttttctacta
     3721 tttctaggta attggattgg acaaataggg ctaaattggt ttgtacttac cacttatcat
     3781 aacgcagttt atctggggat tgtcaatttt tgcagacttg taccaatatt attactaagt
     3841 gtgtgggcag gggcaattgc cgataaatat gataaagggc gattgctgag aattacaatt
     3901 tcatcatcat ttttagtaac tgcaatttta tgtgtgctca cgtatagttt cactgcaatt
     3961 ccaattagcg tcattattat atatgcgaca ttaagaggga ttttaagtgc ggttgaaaca
     4021 cctttaagac aagcaatctt accagattta tcagataaaa tatctactac acaagctgta
     4081 tcatttcatt cattcatcat taatatttgt cgttcaatag ggcctgccat tgctggtgtc
     4141 atattagcag tctatcatgc gccaacaaca tttcttgcac aggcaatttg ttattttatc
     4201 gcagctttat tatgcttacc attacatttt aaagtaacta aaatacctga agatgcaaca
     4261 agatacatgc cgttaaaagt tattatagat tacttcaaat tacatatgga aggtcgacaa
     4321 atatttataa catcattatt gattatggcg acaggttttt catatacgac acttttacca
     4381 gttttgacaa acaaagtatt tccggggaaa tctgaaatat ttggtatcgc tatgacgatg
     4441 tgtgccattg gtggtattat tgcaacgcta gttttaccta aagtacttaa atatattggt
     4501 atggtaaata tgtattattt aagttcactt ttatttggca ttgctttgtt aggtgtggta
     4561 tttcacaata ttgtcatcat gttcatttgt attacattga ttgggttatt tagtcaatgg
     4621 gcacgtacga caaatcgcgt ttattttcaa aataatgtta aagattatga acgtggtaaa
     4681 gtactgagta ttattatgat ggatagaggt atgattccat tgggaagtct gttaatgagt
     4741 atatgtgcag atgtgtttgg cattgttaga actttttcaa taatgggaat aagtactata
     4801 tgcattacaa tggtattcta ttttataaat agaaagttga agttaaagtt ggaggaaagt
     4861 aatcatggta tatcttgaat gggcaaaggc agatagaaat attcaatatc gtgtaattaa
     4921 cgccattatt aaagaacgta tttaccccga gcaaacattt atttcgcaaa aaggatcttt
     4981 aattgaaatt cagtatcata tgcatgtgtt gactattgaa gttgttagaa aaagtgcatt
     5041 agaacgctat gagtttacag gtgatattac ttatttaaat aaaggtgaaa cgtcattaat
     5101 tataacttta gaaggtttgt tagatgtgtt gaatcatgac tttgatatcc ctatttcaga
     5161 gcgactacgc gaagagttaa tacacagtcg agatagttta gttgaaacat ataagcaaat
     5221 gtctcacaga caaacattaa taagtcaaag ttttaaattt tcaagattac cacaagatat
     5281 taactttttt tcatggttac aacatgtaaa agatagtgat aagacagatg atttaactta
     5341 ttctgagagc ttggtaccag aggggcatcc aacacaccct ttaaccaaaa cgaaattgcc
     5401 cttaactatg gaagaagtac gagcatatgc acctgagttt gaaaaagaaa tccctttgca
     5461 aattatgatg attgaaaaag atcatgttgt gtgcacagct atggatggta atgatcaatt
     5521 tattattgat gaaataattc ccgaatacta caatcagatt cgtgtgtttt taaagagttt
     5581 aggtttgaaa agtgaagact atagagcgat tttagtacat ccttggcaat atgatcatac
     5641 gatagggaaa tattttgaag catggattgc taaaaaaata ttaattccaa cgccgtttac
     5701 aatactttca aaagcaactt tatcatttag gacgatgtct ttaattgata aaccatacca
     5761 tgttaagttg cccgtcgatg cacaagcaac aagtgccgtt agaacagtct caactgtgac
     5821 tactgtagat ggaccaaagt taagttatgc tttacaaaac atgttgaatc aatatccagg
     5881 atttaaagtt gctatggaac cgttcggtga atatgcaaat gttgataaag atagggcacg
     5941 tcagcttgct tgtattataa gacaaaagcc tgaaattgat ggaaaaggtg caacagtagt
     6001 tagtgcaagt ctagttaata aaaatccaat agatcaaaaa gttatcgtgg atagttactt
     6061 agagtggtta aatcaaggaa ttactaaaga aagtattacg acatttattg aacgatacgc
     6121 tcaagcatta atcccgcctt taattgcttt tattcaaaat tatggaattg cattagaagc
     6181 acacatgcaa aatacagtag tgaacttggg gccacatttt gacattcaat ttttagtgag
     6241 agatttaggt ggttctagaa ttgatttaga aacattacaa catcgtgtat cagatattaa
     6301 aattacaaat gatagtttaa tagctgattc tatagatgca gtgattgcaa aattccaaca
     6361 tgctgttatt caaaatcaaa tggcagaatt aatccatcat tttaatcagt atgattgtgt
     6421 tgaagaaacc gaattattta acatagtaca gcaagtagta gcgcatgcta ttaacccaac
     6481 actaccacat gcaaatgagt taaaagatat tttgtttgga ccaacaatta ctgtcaaagc
     6541 gttgttaaat atgagaatgg aaaataaagt aaagcaatat ttaaatattg agttagataa
     6601 tccgataaaa aaagaggtgt agtactacat ggcacacgtt aacataaata tatcgaagat
     6661 taaatataac gccaaagtac ttcaaacagt ttttcaaagt aaaaatatac aattcacacc
     6721 agtaattaag tgtatagctg gtgaccgtac aattgtagaa agcttaaaag cgttaggtat
     6781 caatcatgtt gcagaatcca gattggataa cataattagt attgcagatc aggatttaac
     6841 atatacgtta ttgcgtacgc ctgccaaaaa agagatttca gatatgatag aaaaagttga
     6901 tatgagtatc caaacagaat tatctaccat acatcaaata aatgaagtag cagaagtttt
     6961 aggaaaaaaa cataagattt tattaatggt agattggaaa gatggccgtg aaggtgttct
     7021 gacttatgat gttttagatt atattaaaga gattattcac ttgaaaaata tccattttgt
     7081 aggtttagca ttcaatttta tgtgttttaa atctgatgcg ccaagtgatg atgatatctt
     7141 tatgattaat cgattcgtct cagctgttga aagagaaata ggatatcgat tgaaaattat
     7201 ttcaggtggt aattcgagca tgttaccaca acttttatat aatgatttgg gtaaaataaa
     7261 tgaattgcga ataggtgaaa cgttgtttag aggtgttgat acaacgacaa atcaagcgat
     7321 cgctatgtta tatcaagatg cgattacatt ggaggctgag attttagaaa ttaaacctcg
     7381 agttaataca caaacgcatg aatcattctt acaagctatt gtagatattg gttatttaga
     7441 tacaaaagtc gataatattt cacctatgga tcagcatatc aatattttag gcgcttcgag
     7501 tgatcattta atgcttgatt taaatggtca aggacactat caagttggag atcatatatc
     7561 tttttcatta aattatgaag cactttctca ttcgatgtat atgaaaaatt tacataaggt
     7621 atatattgat gattcaaaga ttgatacgct acttcaaaat tttgatgtga aatctcctgc
     7681 tatggtaaac caatattaat atatttatca ataattctaa gttgacaagt tatactacat
     7741 atcgtttgca cggttgtatc ataattgttc aacttagatt ttttgtattt gttgatttat
     7801 caaattaagt gcaacagttc gtcacataaa attgcaacag ataatatcag ctgaattaca
     7861 gggataacgg tcatgctaaa tggtgtcaat tgtattaatg caaagatgat atagcaatga
     7921 tacattatca gtattttgtc taaggaaatg tgctaattgt agtcataatt attagaggaa
     7981 atatatagtc atacatttta gaaatataaa aaagattgaa cgctacttga caatgataat
     8041 tgttatcaat aaaataataa atgaagttat acatattaag gagtggaacg atgagaggtc
     8101 taaaaacttt tagtatattg ggattaatag ttgccttact tttagttgca gcttgtggta
     8161 atacggataa ttcaagtaaa aaagaatcat caactaaaga tactatttcg gtaaaagatg
     8221 aaaatggtac agtaaaagta cctaaagatg caaaacgtat cgttgtatta gagtactcat
     8281 ttgcagatgc attagcagca ttagacgtta aaccagttgg tattgctgat gatggtaaga
     8341 aaaaacgtat cattaaacca gttagagaaa aaattgggga ttatacttct gtaggtacac
     8401 gtaaacagcc aaacttagag gaaattagta aattaaaacc ggatttaatt atcgctgata
     8461 gcagtagaca taaaggtatt aataaagaat taaacaaaat tgcaccaaca ttatcattaa
     8521 agagttttga tggagactac aaacaaaata ttaattcgtt caaaacaatt gctaaagctt
     8581 taaataaaga aaaagaaggc gaaaaacgtc ttgctgagca tgataaatta atcaataagt
     8641 ataaagatga aattaaattt gatagaaatc aaaaagtgct tccagcagta gttgctaaag
     8701 ctggtttatt agcacatcca aactattcat atgttggaca atttttaaac gaactaggat
     8761 ttaaaaatgc attaagtgac gatgtaacaa aaggtttaag taaatatttg aaaggacctt
     8821 acttacaatt agacactgaa catttagctg atttaaatcc agagcgtatg atcattatga
     8881 cagatcatgc taaaaaagat tctgctgaat tcaagaagtt acaagaagat gcaacatgga
     8941 aaaagttgaa tgcagttaaa aataatcgcg tggatattgt tgaccgtgat gtttgggcaa
     9001 gatctcgtgg cttaatttct tctgaagaaa tggctaaaga acttgttgaa ttatcaaaaa
     9061 aagaacaaaa gtaaggtgga agtaaatggc tataaaagaa ataagtagcc aatctgccat
     9121 agatcataaa agaaaaagac gcacaacact cacgtatata gtgagtttgt gctttctttt
     9181 tatttgtata tatttaaata tggcgattgg ttcttcgaaa attaatttta gcgatatcat
     9241 tcactatgtt actggtcata cagatacgaa agcaacgttt ttattgcata atgtacgtat
     9301 gccaaggatg attgcagggt tatttattgg cggtgcatta gcggtatctg gtttgttaat
     9361 gcaagcaatg acacgcaatc cgctagcatc acctaaaatt tttggtgtca gttctggtgc
     9421 atcgtttttc attgtatttg tgacgattat cattccatca ttagaatatt atgcattata
     9481 tttaggtgtg ataggtgcat ttataggtgg tttaactgtt tatacacttt caggtgctac
     9541 gaaaggtatg acacccatta aattagcatt ggctggtatg gccatccatt tgttttttag
     9601 tagtatgact gaaggtatta ttattttgaa tgagaattca aacgaacaag tgatgttttg
     9661 gcttgtcggt tcattatcca gtatgaagtg ggatgaaatt ttaaccattt taccatggat
     9721 tattggtgct ttaattgtaa cgatttttat tggacgtcaa ctaacgatta tggaactagg
     9781 cgatgacatt gctaagggat tgggtcaaaa tataaataaa gttagaatta tcattgggct
     9841 attagtcatt attcttacag gtatgtcggt gtcagtggca ggaccaattg gatttgttgg
     9901 cttaatcgta ccgcatatag tcaaacgcta tgtgagtaag aattatttag tcatgattcc
     9961 attaacattt attataggtg cagatttgtt actactatca gatgtattaa gtcgtttaat
    10021 cacttatcct tacgaatcac ctgtaggtat tgtgacatca ttcgtaggtg cactttactt
    10081 cttatttata acgattaaag gggtgaaaag aatatgatga caacgaaaat tatacgtcgt
    10141 tatagtttaa tcacaatcct tttaattgtg agtatattca taagtttatg tgtagggtct
    10201 gtcatgattc atccgattga tgctattaag ggaatcttta cacaagatga ttttatttta
    10261 aatgagtatc gtatacctag aacattactt ggtattatta tcggtagtag cttggctata
    10321 tcaggtgcaa ttatacaagc tgtaataaga aacccgttag cctcacctga tgttataggt
    10381 atttctaaag gtgccagttt agctgctgta attattatta tgatctttcc aacagcacca
    10441 ttgtttgttt tacctatagg ttcattctta ggtgcctttg cagtaagttt atttttatca
    10501 tttttaattt caaaatatga tgttaaaggt tcaaagcttg ccttaattgg tttagcaata
    10561 ggcgcaatat gtacggcgat tgtgcagttc ttattaatca gaaatccact ggaagcaaac
    10621 aaagcgcttg tttggttgac aggtagtcta tatggacatg atatgtcgaa tatttatact
    10681 atattacctt ggtttttaat aacgatacca atcatcattt tattgagtta tcaattagat
    10741 gtattgaatc taggtgatgc tgttgcaacc gcactcggtt taaaagttaa aactattaaa
    10801 atgctattgc taattttagc agtaatatta gcaggatccg caatttcagt tgtcggtggt
    10861 attagctttt taggattaat tgcacctcat attgcgagac aattaatagg aaataaaaca
    10921 ttacacgtta ttatcatgtc ggggttaatt ggtgctatat tgttaacatt tggagatggt
    10981 ttagcccgtg gcattcatcc gccactggat attcctgtag gggttatcat tgcaattatc
    11041 ggtgcaccat acttcttaat attattacga agaatgaaat aactaacata tgattagagt
    11101 ttaaaaaagg ttaagtacga aatcagtaat tgtacttaac cttttttgaa ttcatcttga
    11161 aaaattacaa gtaatagcgt atatttaata actgtaatta ttcattattt tgcatacata
    11221 aacattttga aagatagaat gataaggaat atgtttgtta actgaataga attctgtata
    11281 tacttaaaac gaatacatag agaaatggat tgattttatg gatagctttt caaggaaaga
    11341 gatagttatt gggagactta agtttattac gatgtcttta attggtatct tattatttct
    11401 agtaccaatt ccagtcgaac aagatggaca gaagcaaaca acgttgcccg tagcattttt
    11461 agcaggcgtg cttaaagatg tattaggtgg cgtaatgcca tttttaattg tgacgataat
    11521 tactttatcg ggtatcataa ctctgatttg ttcaactatt ttaaaagata aattgaaacc
    11581 tgacgggcta atgaacaatg cttttaacgt tagaattggt tggttaattt tacgaatatt
    11641 agcagttgtt tttgcatgga tgacattttt acgaattggt tcaaaggtta tttactcaga
    11701 tgaaacgggt ggattattgt tctcaagttt attgccaaca ttagtggcag tattcttatt
    11761 tgcagctcta tttttaccgc tattaatgga atacggtttg ttagagatgt tgggtcctat
    11821 ttttagaccg gttatgagac ctttatttac attgccagga cgttcgacgg tagataattt
    11881 agcatcattt attggagacg gaactgttgg tgtcttaatt acaagtagac aatatggtga
    11941 aggatattat tctcgtcgtg aggcaacagt tatttcaacg acatttagtg tagtttctat
    12001 cacctttgca attgtagttg ctgaaacagt gcacatgcaa aatcaatttt ttgctttcta
    12061 tttatcagtg atagtatcct gcctcgttgc agcagtcatt atgccaagaa tttggccttt
    12121 aaataaaatt cctgatgagt atgctaagga ggtacctgaa agtgcgcgta ctgaggcatt
    12181 gccagaagga aagacggcat tgagacatgg ctttgatact gcaacagaag ttggtattaa
    12241 agcaccgggc gttattgact tttttaagtc aggattaaaa acagtcattg atatgtggtt
    12301 tgttattttg cctgtagtga tgagtattgg tactattgct accattattg cgaactacac
    12361 gccctttttt gtcatattgg gtaaaccttt tgttccattt ttagagttaa tgcaaatacc
    12421 tgaagcggca caggcttctc aaacgattat tatcggtttt gccgatatgt ttttaccttc
    12481 tatattaatt gaaggtgtac aaaatgatat aactcgtttt gttattgggg cacttagtat
    12541 atcgcagtta atatacttgt ctgaagtagg tggcgtcata cttggttcga agattcctgt
    12601 aagcatcggc aaattgttta tgattttctt gattagaaca atcattacac taccaattat
    12661 ttctttgatg gcacatcttt tgttataaat atatgtgaaa aaggacaact gttaaaatta
    12721 tgagaacagt tgtccttttg tatttgttta tgctgggtgt tgaatcaatt aaaaaaatca
    12781 ttcatgaagc cctcaccatg aatgattttt ttatacaatt tatttagtta attcattgta
    12841 aactttttga tcattttgag tataaataat gtattcgtgg tcttcagtat cgataataac
    12901 gcgattcgtt ttaccaaacg ttgagccgat tctagataca tctttgctgt ctaatttagg
    12961 aactgcatga atatcttggt cttgtgtaat atttttaatt tcacttgtag gaattttgat
    13021 atcagcaact ctccattgaa tacgcacttc attattatct ttctttactg tcattgccat
    13081 tattcaaaca catcctttaa atattttgta aatacatcat aaacgatttt gtaatcgttt
    13141 tcaagagtta tgtgatactt ttttaaattg tgtcatacta atgaatttta acccgaaaat
    13201 atgttcgtgt ttttgttagg gatgtggtaa aatgtgagta ttaaaggaga acaaatatga
    13261 caggtaaaac acatgcttca tgtggcatgc tcgttggagc gctaacaaca caatattttc
    13321 aaacggatat tttttcgtcg gttacggtta tcattctagc aactctagct agcttattac
    13381 ccgatatatg tcacactcaa agtaagattg gcagaaggtt taaggtaatt agtttttttg
    13441 tgagattgat ctttggacat cgaaccttta cgcattcaat attatttatc gcaatcatag
    13501 catttttatt gcaaattatt cagacgccta attattatat ggcagcaatt ataattgggt
    13561 tagtgtcaca tgttatacta gatatgataa caccaagagg cgtgaaatta ttttatccgt
    13621 taccgtttaa tgtgaagaca ccgattcaat ttaaaacagg tggacttgta gacttatctt
    13681 tagctacagc gttaatggtt ggaacagttt atgttttatt tcagcctttc atcaatgata
    13741 taataagcaa ctggaatact aagtttttat agaaaataaa ttattaaagg ttacaaactc
    13801 agcaggaggc ataaaatgct agataaaaat caattagcta aatataaaca agatcatttg
    13861 tgtgaatatg aaaaaataat gagtaacaat gaaaaagaag cacttgaaga gaaggtagcg
    13921 tcattagatt tagattttat tgccaaatta tataacgatt tatacatcaa taagaaaaca
    13981 atagatgatg tatctgcagt ttctgaagtg aaatatgata ttaaatcaca aatgagtgat
    14041 gatgagatta agcgtttaga ggaacaagga cttcaagcta ttaaagaagg acaatttgca
    14101 gtacttttga tggcaggtgg tcaaggaaca agacttggtt acaagggccc taaaggttcg
    14161 tttgaaattg aaggtgtaag tttatttgaa cttcaagcta accaattaaa aacattgaat
    14221 catcaatctg gacatacgat tcaatggtat attatgacaa gtgatatcaa tcatgaagaa
    14281 actttagctt atttcgaagc acatagttat tttggatatg atcaagaagc aatccatttc
    14341 tttaaacaag ataatattgt ggcgcttagt gaagaaggga agttaatttt aaatcaacag
    14401 ggtcgtatta tggaaacgcc gaatggtaat ggtggcgtgt ttaaatcttt agacaaggca
    14461 ggatacttag aagaaatgtc taataatggc gttaagtata ttttcttgaa taatatcgac
    14521 aatgttttag taaaagtgtt ggatccacta tttgcaggat ttacggtaga acatgattac
    14581 gatattactt ctaaaacgat tcaaccaaaa ccaggagaaa gtgttggacg tttagttaat
    14641 gtcgattgta aagatacagt actggagtat tcagaattag atccagaagt tgcaaatcaa
    14701 tttaacaatg ctaatatcgg tattcatgca tttaaacttg gttttatttt aaacgctgta
    14761 aatcgtgagt taccttatca tttagctatt aagaatttga aacaattaga tgagaacttt
    14821 ggggttattg aacaaccaac tttaaaattc gaattgttct attttgacat atttacttat
    14881 ggaactagtt ttgtcacgtt acaagttcct agagaagaag aattttcacc tcttaaaaat
    14941 aaagaaggta aagatagtgt tgcaactgca acagaagatt tacgtagaat gggtttaatt
    15001 taatgatagg cggtgactat gatgtccaaa tcaactaaaa aaagtaatga cacaatcgta
    15061 gaaacattta aggatatcat ccctttatca tttggagaag aaattggtaa tgcggcatct
    15121 catggtgttg cagctttgtt aacattatta gtgttaccct atgcggctgt gcacagttat
    15181 attgcacatg gtacgcttgc gtctgtgagt atgtctattt atgttatttc tatctttatg
    15241 atgtttattt catctactat ttatcattct atgcaaaatg aaacacctca taaatatatt
    15301 ttaaggatta tcgatcacag tatgatttac gtagcaattt ctggtacata tacgcctatt
    15361 ttgttaacag ttgtaggtgg ttggataggt tggacggtat ttattttatt atggggaacg
    15421 acactttggg ggattttata taaatccata gctgtcaaag ttaaccaaaa gttaagctta
    15481 attgtctatt tagtgatggg ctgggtaggt attatcttgt taccaattat ttttattcgc
    15541 acatcatgga tattcatatt attcattttc ttaggtggtg tgtcttatac aattggtgca
    15601 tggttttatg cacaaaagaa tagaccatat tttcatatga tttggcatat ttttattgta
    15661 atagcatcac tattgcattt aattgcgatc ttatatttta tgtagtcgtt tagaaaagct
    15721 gggggaaact ccgctttttt tattacataa atcattctaa taggggattg tattgtaata
    15781 gaattatcgt taagatttga aagtcaaaag tgtttataca tatgaaaacc aattatttgt
    15841 aaataaaatc ttataaataa atatatagaa ggaggtattt catgcgatta aagtcaatca
    15901 taactgttat agctttaata ttaattatgt ttatgtcagc gattgaatca tctattattt
    15961 cgcttgcatt acctacaatt aaacaagatt taaatgcagg aaatttaatt tcattaattt
    16021 ttacagcgta ttttatcgca ttagtaattg ccaatcctat agtgggagaa ttactttcga
    16081 gatttaaaat tatttatgtg gcaattgcag gattactttt atttagtata ggtagtttta
    16141 tgtgtggttt aagtactaat tttactatgc taattatatc acgcgtgata caaggttttg
    16201 gatcaggtgt attgatgtca ttatcgcaaa ttgttccaaa gttagcattt gaaattccgt
    16261 tacgatataa aattatgggc atagttggca gtgtttgggg tatttcgagt atcattggac
    16321 cgcttctagg tggtggtata ttagaatttg caacatggca ttggttattc tacataaata
    16381 taccgattgc gatcattgcc attatattag ttatatggac atttcatttt ccagaggaag
    16441 aaacagttgc taaatcaaaa tttgatacta aagggctcac gctattttat gtatttattg
    16501 gattgattat gtttgcttta ttaaaccaac agctattact tttaaatttc ttgagtttta
    16561 tcttagctat cgttgtggca atgtgtttat ttaaagtaga aaaacatgtt tcttcaccat
    16621 ttttacctgt ggttgaattt aatcgttcga ttactttagt ttttataacg gaccttctaa
    16681 cagctatttg tttaatggga ttcaatttat atattccagt ctaccttcaa gaacaactag
    16741 gattatctcc attgcaaagt ggattggtta tttttccttt atctgtagct tggattacat
    16801 tgaattttaa tttacatcga attgaagcaa aactatcaag gaaagttatt tacttactat
    16861 catttacatt gttactagta agtagtatta tcatttcatt tggtattaaa ttgccggtac
    16921 ttatagcatt tgtgttaatt ttggcaggat taagttttgg atatatttat acgaaagata
    16981 gtgtaattgt ccaagaggaa actagcccat tacaaatgaa gaaaatgatg tcattttatg
    17041 gattaactaa aaatcttggg gcatcaatag gttcaacaat aatgggatat ctttatgcga
    17101 tacaatcagg aatctttggt ccaaacttac acaatgtgtt aagtgctgtt gctgtaatta
    17161 gcattgggct tattgtttta tgggtcgtat tttttaaaga acagtcatct caatcaaaag
    17221 aatagaatta tgattaaaat tgatgtagtg taattaaagt aagaaataat aaatttccta
    17281 gatactagat aaatcgttca atattttatt aataaggagg ccaatgattg tgaattatct
    17341 taaacataag ttttataact tgttaactac aatgattgtt ctctttattt ttgtactttc
    17401 tggtgcgatt tttttaacat ttctagggtt tggtttatat ggattaagta gaatacttat
    17461 ttattttagg ttgggtgact ttacatataa tagaagtatg tacgataacc tattatatta
    17521 tggcagttat ataatctttg ggtacttcat catatttgca gtcgagcatt taatggatta
    17581 ttttagaaaa atgttgcctg aaaatgcata ttttagaggc gcgacttttc atttgatttc
    17641 ttacacagtt gcaacaacgt tattttattt catcattcat ttaaattatg tttatatcaa
    17701 tatcgatttt tgggtcatca tggttattat agggttctta tatgtttgta agcttcaatt
    17761 ttaccctgaa agtaaaaatt taaataatag aaaatagata tctgaagttg agggcacata
    17821 tgtgttccaa cttctttttg ttcaatagaa gaatcgataa tagtgagtct tagtgctcaa
    17881 tttgtggtaa ataagttaaa taaccattgt atgagtctga gaaataaaat aaattattag
    17941 gccctacaat gttatattgt tagtttttta agtacacatt agctgtgcct aatgtgtaag
    18001 aaccaataat gatttattat gtagtgcttc tttatcattt gagtactact cccattatgt
    18061 taatggctat atgtattaaa gggacaagtg tatatctgtt ttaaaaagga ggaattatga
    18121 tggctaaagt tgaattaaca acccggagac gaaacttcat agttgctgtt atgttgatta
    18181 gtgcgtttgt agctatttta aatcaaacat tattaaatac agcgttacct agtataatga
    18241 gagaattaaa tattaatgaa agtacatcgc aatggctagt tactgggttt atgcttgtta
    18301 atggcgtcat gatacctctg acggcatatc taatggatag aattaaaact agacctttat
    18361 acttagcggc gatggggaca tttttattag gttctattgt tgcagcctta gctccgaatt
    18421 ttggagtttt aatgttagca cgtgtaattc aagcgatggg tgcaggcgta cttatgccct
    18481 taatgcaatt tacgttattt acattgttca gtaaagaaca tcgaggtttt gcaatgggac
    18541 tagcaggttt agtaattcaa tttgcaccag caataggccc tacagttaca ggattaatta
    18601 ttgatcaagc gagttggcga gtaccattta ttataattgt aggaattgct ttagttgcct
    18661 ttgttttcgg cttagtttca atctcaagtt acaatgaagt gaaatatacg aaattagata
    18721 agcgctcagt aatgtattca actattggat tcgggttaat gctatacgca tttagtagtg
    18781 caggagattt aggatttaca agtccaatag taataggtgc gttgataata agtatggtta
    18841 ttatctattt atttatacgt agacaattta atattactaa tgtactttta aatttaaagg
    18901 ttttttaaaa atagaacatt tgcattatgt acgattagtt caatgattat aatgatgtca
    18961 atggttggac ctgcgctgct tataccgcta tatgttcaaa atagtttatc tttatctgcc
    19021 ttgttatcag gacttgttat catgcctggt gcaataataa atggtattat gtcagttttt
    19081 acaggtaaat tttatgataa gtatggtcct agaccattga tttatactgg ttttacaatt
    19141 ttaacaatta ctacaattat gttgtgtttc ttgcatacag acacatctta tacgtattta
    19201 atagtcgtat atgcaattag aatgttttca gtttctttac tcatgatgcc gataaatact
    19261 acaggaatta attctttgag aaatgaagaa atctcacatg gcacggctat tatgaacttt
    19321 ggtcgtgtaa tggctggttc actaggcaca gctttaatgg ttacattaat gagttttggt
    19381 gcaaaaatat ttttatctac atcgccatcg catttaactg caactgaaat taaacagcaa
    19441 tccattgcta taggggtgga tatctcattt gcttttgtag ctgtgcttgt tatggcagct
    19501 tatgtgatag cactttttat aagagaacct aaagaaatag aaagtaatag aaggaaattt
    19561 taaaataatt atagtagttg gtctatttaa aataataggc taactgcttt ttttatttaa
    19621 taaaaagttt tatactttta gtgatagact aagcaaaaat tgttatttgc tatgatgtag
    19681 atgtcttaaa atgattaagg gggatttgct ttgttaacgg tagatcaagt gaaagaattg
    19741 gtaggagaaa ttaaagatcc tattatagat gtgcctttaa aagaaacaga aggtattgtt
    19801 gaagtttcta ttaaggaaga aaaagaacat gtgagtgtta aattagcaat ggcacaatta
    19861 ggtggtgcac cgcaattaga tttacagatg gctgttgtta atgcattaaa agaaaacggt
    19921 gcgaaaacgg tcggtatacg atttgaaaca ttgccggaag aaaaagtaaa tcaatttaaa
    19981 ccaaaagaag aaaataaacc taaaacgata gaaggcctat tatctcaaaa taatccagtc
    20041 gaatttattg caatagcctc cggtaaaggt ggtgtcggta aatctactgt tgcagtaaat
    20101 ttagccgttg ccttagctcg tgaagggaaa aaagtcggat tagtagatgc cgatatatat
    20161 ggatttagtg taccagatat gatgggtatt gatgaaaagc ctggaattaa agggaaggaa
    20221 gtaattccag ttgaacgtca tggcgttaaa gttatatcaa tggccttttt tgtggaagaa
    20281 aatgcgccag ttatatggag agggccaatg ttaggtaaaa tgttgacgaa tttctttaca
    20341 gaagttaaat ggggagacat tgaatattta atactcgatc ttccacctgg aacaggagat
    20401 gtagctttag atgttcatac gatgttacct tcaagtaagg aaattattgt aacgacacct
    20461 catcctacag cagcatttgt tgcagctcgc gcaggtgcga tggcaaaaca tacggatcat
    20521 tctattcttg gcgtaattga aaacatgagt tattttgaaa gtaaagagac gggtaataaa
    20581 gaatatgtct ttggcaaagg tggcggtact aagttagctg atgaacttaa tactcaatta
    20641 cttggggaat tacctttaga gcaaccatct tggaatccaa aagattttgc accgtcaata
    20701 tatcaatcag atgatcgtct aggtaaaatt tatagctcga ttgcacaaaa agttatagct
    20761 gctacaaata aataggtata atatatgcta aacgtacaaa attactttta ttttgtacgt
    20821 ttttatgttg atttgttttg gaatgctggt aaaataagtt cttgtgttaa gcaataaacg
    20881 cgttgaaaaa gaagcgggtt gtgaacacaa aaagttttaa aaaagttatt gactttaaat
    20941 tccaaagttg ataatatgat aaagtcgtca aaaacgacgc agttgttttt aaagaagaat
    21001 ttcaaaagtg taaaacttac cattgaaata actataaaaa caatatagaa taaataaagt
    21061 aatcgttcaa aaagttattg acttcaagaa acaaatgaag tagaataaaa gagattgaat
    21121 at
//
LOCUS       DAPDIM010000050        20871 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000050 DAPDIM010000000
VERSION     DAPDIM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 20871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20871
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.050"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(27..1286)
                     /gene="femB"
                     /locus_tag="RFE25_001978"
     CDS             complement(27..1286)
                     /gene="femB"
                     /locus_tag="RFE25_001978"
                     /EC_number="2.3.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine glycyltransferase FemB"
                     /protein_id="HDU2817022.1"
                     /translation="MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLL
                     GIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQC
                     LYVKLDPYWLYHLYDKDIVPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMG
                     VLNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGF
                     VSKTDDYFYNFIDTYGDKVLVPLAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDK
                     QMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEKY
                     NQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELI
                     GDFYKPIHKVKYWLFTTLDKLRKKLKK"
     gene            complement(1305..2567)
                     /gene="femA"
                     /locus_tag="RFE25_001979"
     CDS             complement(1305..2567)
                     /gene="femA"
                     /locus_tag="RFE25_001979"
                     /EC_number="2.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine glycyltransferase FemA"
                     /protein_id="HDU2817023.1"
                     /translation="MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVG
                     IKNNNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRC
                     LYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSV
                     LDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDTSESKAFA
                     DRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPEN
                     KKAHNKRDNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSN
                     AFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIE
                     YVGDFIKPINKPVYAAYTALKKVKDRIF"
     gene            complement(2889..3617)
                     /locus_tag="RFE25_001980"
     CDS             complement(2889..3617)
                     /locus_tag="RFE25_001980"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HDU2817024.1"
                     /translation="MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGP
                     VIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDT
                     GVYGLIIPDLPYELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTM
                     NATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIV
                     KRFKSNTREEIIRYLQSIQQTLNN"
     gene            complement(3610..4824)
                     /gene="trpB"
                     /locus_tag="RFE25_001981"
     CDS             complement(3610..4824)
                     /gene="trpB"
                     /locus_tag="RFE25_001981"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HDU2817025.1"
                     /translation="MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKAD
                     PEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQA
                     LLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
                     AKVVAVEEGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKE
                     IKSQILKKEGRLPDAIVACIGGGSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALA
                     IGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHSYYHDIGRVTFENAS
                     DTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETI
                     RQYMAERGLAND"
     gene            complement(4817..5424)
                     /locus_tag="RFE25_001982"
                     /pseudo
     CDS             complement(4817..5424)
                     /locus_tag="RFE25_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499897.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
     gene            complement(5424..6206)
                     /gene="trpC"
                     /locus_tag="RFE25_001983"
     CDS             complement(5424..6206)
                     /gene="trpC"
                     /locus_tag="RFE25_001983"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HDU2817026.1"
                     /translation="MTILAEIVKYKQSLLQNGYYQDKLNTLKSVKIQNKKSFINAIEK
                     EPKLAIIAEIKSKSPTVNDLPERDLSQQISDYEKYGANAVSILTDEKYFGGSFERLQA
                     LTTKTTLPVLCKDFIIDPLQIDVAKQAGASMILLIVNILSDKQLKDLYNYAISQNLEV
                     LIEVHDRHELERAYKVNAKLIGVNNRDLKRFVTNVEHTNTILENKKPNHHYISESGIH
                     DASDVRKILHSGIDGLLIGEALMRCDNLSEFLPQLKMQKVKS"
     gene            complement(6208..7206)
                     /gene="trpD"
                     /locus_tag="RFE25_001984"
     CDS             complement(6208..7206)
                     /gene="trpD"
                     /locus_tag="RFE25_001984"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HDU2817027.1"
                     /translation="MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSE
                     REIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGV
                     KVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQ
                     PVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGA
                     NGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNI
                     LNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE"
     gene            complement(7212..7778)
                     /locus_tag="RFE25_001985"
     CDS             complement(7212..7778)
                     /locus_tag="RFE25_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDU2817028.1"
                     /translation="MILVVDNYDSFTYNLVDIVAQHTDVIVQYPDDDNVLNQSVDAVI
                     ISPGPGHPLDDQQLMKIISTYQHKPILGICLGAQALTCYYGGEVIKGDKVMHGKVDTL
                     KVISHHQHLLYQDIPEQFSIMRYHSLISNPDNFPEELKITGRTEDCIQSFEHKERPHY
                     GIQYHPESFATDYGVKIITNFINLVKEG"
     gene            complement(7775..9181)
                     /locus_tag="RFE25_001986"
     CDS             complement(7775..9181)
                     /locus_tag="RFE25_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HDU2817029.1"
                     /translation="MDIFYKKIKANVTPEVLAQLHSKKIILESTNQQQTKGRYSVVIF
                     DIYGTLTLDNDVLSVSTLKESYQIIERPYHYLTTKINEDYHNIQDEQLKSLPFISGYV
                     GTCSFDLVRHEFPKLQSIQLEDHKQHDVRLYMVEQVYVFDHYKDELYIIATNQFSNST
                     KSDLENRVNKSIEDLTKIQPFMPTQDFDFKTKEIQSNISEERFIEMIQYFKEKITEGD
                     MFQVVPSRIYKYAHHASQHLNQLSFQLYQNLKRQNPSPYMYYLNIDQPYIVGSSPESF
                     VSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVS
                     KIGTSKITKLMVIEKYEHVMHIVSEITGKINQNLSPMTVIANLLPTGTVSGAPKLRAI
                     ERIYEQYPHKRGVYSGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPE
                     KELNETKLKAKSLLEVRP"
     gene            complement(9673..10704)
                     /locus_tag="RFE25_001987"
     CDS             complement(9673..10704)
                     /locus_tag="RFE25_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDU2817030.1"
                     /translation="MEPILEMIKTLTGINSPSGDTEEAIQFVEKYAKDLGYQTTLTNK
                     GALLITVPGKNDEVQRCITAHVDTLGAMVKEIKEDGRLAIELIGGFTYNAIEGEYCQI
                     KTDAGQIYTGTICLHETSVHVYRNNHEIPRDQKHMEIRIDEVTTSEEDTKSLGISVGD
                     FVSFDPRTVITSSGFIKSRHLDDKASVAMILQLLKKLKEEQIILPHTTQFYISNNEEI
                     GYGANASIDSKIKEYIALDMGALGDGQASDEYTVSICAKDASGPYHKQLKSHLVNLCK
                     INNIPYKVDIYPYYGSDASAALHAGADIRHGLFGAGIESSHAMERTHIDSIKATEKLL
                     YAYCLSPIE"
     gene            10869..11960
                     /locus_tag="RFE25_001988"
     CDS             10869..11960
                     /locus_tag="RFE25_001988"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDU2817031.1"
                     /translation="MTTVLFVGLGLIGGSLASNIKYHNPNTNIIAYDADTSQLDKAKS
                     IGIINEKCLNYSEAIKKADVIIYATPVAITNKYLSELIDMPTKPGVIVSDTGSTKAMI
                     QQHESNLLKHNIHLVSGHPMAGSHKSGVLNAKKHLFENAYYILVYNEPRNEQAANTLK
                     ELLSPTLAKFIVTTAEEHDYVTSVVSHLPHIVASSLVHVSQKNGQEHHLVNKLAAGGF
                     RDITRIASSNAQMWKDITLSNKTYILEMIRQLKSQFQDLERLIESNDSEKLLSFFAQA
                     KSYRDALPAKQLGGLNTAYDLYVDIPDESGMISKVTYIMSLHNISISNLRILEVREDI
                     YGALKISFKNPTDRERGMQALSDFDCYIQ"
     gene            complement(12097..13359)
                     /locus_tag="RFE25_001989"
     CDS             complement(12097..13359)
                     /locus_tag="RFE25_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDU2817032.1"
                     /translation="MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADT
                     KRQGSVILAATPKLKELGIKTGSRLFEIPHRNDIYIINPSMRKYLNVSVAISKIALRY
                     IPPEDLHQYSIDEFFMDVTDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLL
                     SKIAMDVEAKHSQNGIAEWRYQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGD
                     LAKYPYKFLKKEFGILGVDMHLHANGIDQSKVREKHKISNPSICKSQILMRDYHFDEA
                     KVVMQELIEDVASRVRARKKVARTIHFAFGYSDEGGVHKQYTLKDPTNLEKDIYKVVM
                     HFADKLCNKQALYRTLSISLSQFINEDERQLSLFEDEYQRKRDECLAKTIDQLHLKYG
                     KGIVSKAVSFTEAGTKHGRLGLMAGHKM"
     gene            13507..13692
                     /locus_tag="RFE25_001990"
     CDS             13507..13692
                     /locus_tag="RFE25_001990"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HDU2817033.1"
                     /translation="MPIVNVKLLEGRSDEQLKNLVSEVTDAVEKTTGANRQAIHVVIE
                     EMKPNHYGVAGVRKSDQ"
     gene            complement(13780..14763)
                     /locus_tag="RFE25_001991"
     CDS             complement(13780..14763)
                     /locus_tag="RFE25_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDU2817034.1"
                     /translation="MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLI
                     ALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDS
                     IMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINP
                     EYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFR
                     HDPEGDFGRVRRQQQVMQTLKKEMVNFRTVVKLPKVAGILRDYVNTNIPDSGIFQTGL
                     SFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAIKDFLDED"
     gene            14900..15409
                     /gene="msrA"
                     /locus_tag="RFE25_001992"
     CDS             14900..15409
                     /gene="msrA"
                     /locus_tag="RFE25_001992"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDU2817035.1"
                     /translation="MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYE
                     QVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVIDPLDTGGQYQDRGPQYQTAIFYT
                     NDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQK
                     IRQEYKNKQ"
     gene            complement(15612..18134)
                     /gene="mprF"
                     /locus_tag="RFE25_001993"
     CDS             complement(15612..18134)
                     /gene="mprF"
                     /locus_tag="RFE25_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDU2817036.1"
                     /translation="MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVE
                     FSKINRMSLVLLFIGGGASLVILSMYDVILSRALKMDISLGKVLRVSYIINALNAIVG
                     FGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD
                     KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCG
                     VIVDAHVSFMSFIAIFIIAALSGLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLL
                     LYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTSFLMSYQKDIIAKIP
                     SLSLAILVFFTSMIFFVNNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYK
                     QSRRAIIFAMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRN
                     IVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMHTSVLRYYFWLTILIIAIIIGMIAW
                     LFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYKAS
                     SLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGE
                     EAIIDLTQFSTSGKKRRGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDN
                     RQEMHFSVGQFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYFNDAISVDLIRWLPELD
                     LPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYR
                     FQGLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK"
     gene            complement(18615..19823)
                     /locus_tag="RFE25_001994"
     CDS             complement(18615..19823)
                     /locus_tag="RFE25_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDU2817037.1"
                     /translation="MNENEKNIRKNFLKFTESRYMKFVGGNDLVFSLIALVLLGIVIF
                     IFEKVSYVFDPFIIVFKTIAAPIIVSLILFYLFNPIVNMMERYRIPRVAGISIIYLAV
                     VGVITLIVNLLIPIIGSQVDSLVKNSPQYLEKLINSIDKIANNTFFSSYYSQINDWLN
                     SLPKKIPSMLSEFTDGFGSKIATFAETIANIGVVIVTTPFVLFFMLKDGHHFKEFSTN
                     IMPPKFRKDFHDLLEKMSVQVGSYIQGQIIVSFCIGILLFIGYSVIGLKYSLVLASIA
                     AVTSVVPYLGPTIAISPAIVIAAITSPWMLLKLAVVWTLVQFVEGHFISPNIMGKTLK
                     IHPLTIIFILLCAGKLLGIVGVILGIPGYSILKVLVTHLFQLFKRRYNRFYGNDVGEY
                     DIKESNKIVE"
     gene            complement(19816..19983)
                     /locus_tag="RFE25_001995"
     CDS             complement(19816..19983)
                     /locus_tag="RFE25_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817038.1"
                     /translation="MKKGLINPKLSVLHGRFVAVKGICMVSLMLVILHKWTVFIQHLM
                     NILSGGESIIE"
     gene            complement(19958..20809)
                     /locus_tag="RFE25_001996"
     CDS             complement(19958..20809)
                     /locus_tag="RFE25_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDU2817039.1"
                     /translation="MGEYIVTKTLNNNVVVCTNNDQEVILIGKGIGFNKKEGMALNDQ
                     TITIEKIYKLESEQQKAHYKSLVEIADDNVLQVIIDSLNFISNTAMNVDSKQLVVSLT
                     DHIIFAYKRLKQNQVISNPFVMETMQLYSDAYHIAKQVIDQLNAALDVHFPEDEIGFI
                     ALHIASNTEDLSMHEMTLINNVIKKGIDIIESDLVTTVDKESLQYQRFIRHVQFLIRR
                     LRRKEYIHAQDDFVSMIKNHYPICYNTAYKILTMIQKQFDVNISESEIIYLTLHIHHF
                     EERINQS"
BASE COUNT         6800 a         3764 c         2934 g         7373 t
ORIGIN      
        1 actataagcc ctaacatcat ttacatctat ttctttaatt ttttacgtaa tttatccaat
       61 gttgtgaaca accaatattt cactttatga attggtttat agaaatcccc tattaattct
      121 tcgatttgta cattaaatcc acgtttaaag cggtatacgc cataatcttc actgttttcc
      181 gtaaaatcac ctgataaacc atagaaatta taacgatcat agccattatc gaagcaatag
      241 ttaatcataa accaatgcat catgtatggt cccataaatt gattatattt ttctgatgaa
      301 ccaccagaga aataattcac ttcatatgca tttgcaaaat aaacgccaga agcaaggttt
      361 agaattgggc cgtccgtttt gctcaattca cttgcattca ataattcatg ctgatcatga
      421 tcaatttgct tatctaattc tgcaattttc ttcatttgtt tatctgattt gttttctttc
      481 gccatcattt gatcacgacg attttctttg tcattcaatt cctgttgcaa ctttaacaca
      541 tattcatcaa ggtcaatata tgctaatggt actaatactt tatctccata tgtgtcaata
      601 aagttataaa aataatcatc tgtttttgac acaaatccag cacgctcttc agtttcacga
      661 tataaatcta agaaaagatt gaactcatca cgttcaagga atctgacttt aacaccatag
      721 tttatcgctt tattaatatt acgtttacgt tgactatcaa atgtcttttt caatgtttcg
      781 ggtgttttac cttcaaggtt taatacgccc atccatcgta cttggctcga tgtatcatac
      841 tcagttgtaa agccatgatg ctcgtaacca tgtgatttaa acaagtttac taaggcatca
      901 tttttctcgc gaccttcaaa tggcacgata tctttatcat atagatgata taaccaatac
      961 ggatctaatt taacatataa acattgatgt tgctgtaaat atttatctaa ctcttttaaa
     1021 taataatcaa ctaatcctaa atctgaaaaa tccattactg gaccacgatt cgaatagtaa
     1081 acataacttc ccatagtagg aattttagag aaaaggcttg ctgcaattac tttgttattg
     1141 tcgtctttaa tacctaataa aactacttca aagccatcat tctcacgggt aactatattt
     1201 tcttttactt ggaaataatg actttccaat gatggatttt gtacaaagtt gtcaaattcg
     1261 gtaacagtta actctgtaaa tttcatgttt tgataattcc cttcctaaaa aattctgtct
     1321 ttaacttttt taagtgcggt atatgctgcg taaacaggtt tattaattgg tttaataaag
     1381 tcaccaacat attcaataat ttcagcattg taaccttttt tgaatttaac tacaccagca
     1441 tcttcagcat cttctgtaaa tttaccacta acaccataga aattataacg gtcaatgcca
     1501 tgatttaatg cataattaat catttcccat tgcactgcat aacttccggc aaaatgacgg
     1561 aatgcatttg atgtaccacc agcataataa acaacttcaa atgggttgat aaagaagaaa
     1621 ccagcagaga taggtaattc attaccatgt tcttcttgta gacgtttacc ttcttcaatc
     1681 ttttgctcat tagcatcaag ttgttgttgt aagttatctc gcttgttgtg tgctttttta
     1741 ttttcaggac gtttttcaat atcctttaac gctttattta aatctttatt taaaatatca
     1801 cgctcttcgt ttagttcttt aatatattca tcaaagttga tatacgctaa aggtactaac
     1861 acacggtctt tgtaatattt taagcgattg tagtaaaatt tgtcatcacg atcagcaaaa
     1921 gcttttgatt ctgacgtatc ttccataaat gatctaaaaa ttggcagttc ttcttcagat
     1981 aaatatctta ctttaacacc attcttttta acttttttcg tgtttctttt tctaagtcca
     2041 tccatatttt taatgatgtc atctgctgtt ttatctttta aatctaacac tgagtgataa
     2101 cgaatttgta gcacaggatc aaatccttta tggaatccag tatgttcaaa tcctaagtta
     2161 ctcattttat caaagaacca atcattacca gcattacctg taatctcgcc atcatgattc
     2221 aagtattgat atggtaaata tggatcgata tgtaggtata gacaacgatg ttttttaaca
     2281 tattttgata attcattaaa gaaaaagtgt acgagttctt gattttcata atcgatcact
     2341 ggaccgcgat ttgaataaaa atacttgaac actttcataa caggtacagc agtaagtaag
     2401 caagctgcaa tgacctcgtt attattgttt tttattccca ctaaatgtgt ttcataacct
     2461 tcagcaagct ttaactcata gtggccaaca gtttgcgtga aatgactgta tggcatgcta
     2521 tctgtaaagg caccaaactc tttagctgtt aaatttgtaa acttcattat cattactcct
     2581 atttgtctct cgttaattaa tttcatttcc gtatttgcag tttttctatt tcccctctgc
     2641 aaatgtcaaa aataataaat ctaatctaaa taagtataca atagttaatg ttaaaactaa
     2701 aacataaacg ctttaattgc gtatactttt atagtaatat ttagattttt gcatacaatt
     2761 tcaaaaaaag taatatgaac gtttgggttt gctcatatta cttttgtatc atttctattc
     2821 aattttataa ttcaccgttt ttcacttttt caaacagtat tcgcctaatt tttttaaatc
     2881 aagtaaactt aattattcaa tgtttgttgg atagattgta aatatctaat gatttcctca
     2941 cgcgtgttag atttaaatcg cttaacgatt tcgctaccaa tgacgatgcc atctgcaacc
     3001 tcttttatat ctgcaacatg ttgtggtgtt cttataccaa atcctgcgac aactggcaca
     3061 ttggctatcg ctttaattga ctcaattttt cgttttaatt ctggatgaaa cgcaccgttt
     3121 tgtcctgttg tcgcattcat cgtcacagta taaataaagc cttccgcatg agatacgata
     3181 tcttttatac gtttgtcatc agtagtcatc gcaactaacg atatgatttt gacgccatag
     3241 tgactaaatt gttgttttaa acgctgcgat aattcatatg gtaaatcagg aataattaag
     3301 ccgtagacac cagtatctcg acatttttca aaaaacgctt gttctccata atgacaaata
     3361 atattataat acgtcattaa tacatagtta cacttaattt gatcaccatg tttttctaat
     3421 tgattgaaaa tataatctat cgtgatgcct tgtttaatcg cttgttgacc tgcttccatg
     3481 ataactggac catcagcaac cggatcagag aaaggtacac caatttcaat tatatctgca
     3541 ccattttcac tcaacaatgt tgcattttca atcaaatctt tattgcccat aatataaggt
     3601 ataaataatt tagtcatttg caagacctcg ctctgccata tattgtctaa ttgtttccat
     3661 atctttatcg ccacgtccag aaatagttac tacaataata tcttctttcg acatcgtagg
     3721 cgctagtctt tcaacataac tcagtgcatg tgcactttca attgcaggta taataccttc
     3781 atgttttgta aagttgatta aagcattcat tgcttgtgta tcacttgcat tttcaaaagt
     3841 tactctacca atgtcgtggt aataagaatg ttcaggccca ataccaggat aatcaagtcc
     3901 tgctgaaata gaatgtgcta gttgcacttg cccaccttca tcttgaatta aatacatttt
     3961 agtaccatgt aatacgccag gtgatccttt gccaattgca agtgcatgtt tatcagtatc
     4021 ctcgccttga cctgcggctt caacaccgta taatgcaaca tcatctttaa taaatggata
     4081 aaatgtaccg attgcatttg agccaccacc gatacatgct acaattgcat ccggaagtcg
     4141 accttctttc ttcaatatct gtgattttat ttctttacca atgacactct gaaaatctct
     4201 aacaatcgtt gggaatgggt ctggacctaa tgcagaacct aataaataat gtgtatcatc
     4261 tacatgactt acccaatatt gcaatgcttt attaactgca tccgataaag tcccttgacc
     4321 ttcttcaact gccacaacct ttgcaccaag taattccatt ctaaatacat taagttgttg
     4381 tcttttaata tcttcacttc ccataaagac aacaagttcc atatcaaata atgcagcaac
     4441 cgtagcacta gctacaccat gttgacccgc accagtttca gcaacaagct tcttcttgcc
     4501 cattctttta gcaagcaacg cttgacctaa cgcattatta attttatggg cgcctgtatg
     4561 atttagatcc tctcgtttca aatatatttt agcgccacct aggctttcag tatatgatgc
     4621 agcatatgta agtggtgtcg cgcgtcctac atactctgat aaatagtatt ccagttctct
     4681 ttgaaactct gggtctgctt ttgcctcttt ataagctttt ttcaactcaa taattgctgg
     4741 cattaatgtt tctggaacat attgccctcc atattcacca aagaaaccta attcatctgc
     4801 ttctgtttgt atttgtttat tcattgtctc tatctccttt cacaatattt acaattgctg
     4861 tcattttttc tatatctttt cgcccattta cttctatacc tgatgcaaga tcataacctt
     4921 gatgtgataa tttaagttga ttaactgttt gaatattttc agagttaatg cctcctgcta
     4981 tcaaataagg tatgtctttt atgtgcttca aaatagtcca gtcatatgtt tgaccggtac
     5041 caccatacga cactgagggt gtgtcgataa taaataaatc tacgaaccct ttatatttat
     5101 ttatgttttg gattatgttt tcatctgcag ctaaagcttt agtgatttta atgcttgaat
     5161 atttcttttt aatttcctgt ataaaatcaa tagattctgt gccgtgtaac tgtattgtgg
     5221 ttcaattgtt gttaaatcag gatttaccat gacacatact ttatcgatat gatttggaac
     5281 agcagacgct aactttttta tttgggtaat tgtttgatgc cttttacttt tttcataatg
     5341 gatgaaacct atcgcatcaa taggtaattg actggccgct gtaacatcct ttattgatgt
     5401 aaagccacaa aatttcaatt tcatcatgac ttcacctttt gcattttcag ttgtggtaaa
     5461 aattcagata gattgtcaca acgcataagc gcctcaccta ttagtaagcc atcgatacca
     5521 ctatgcaaga tttttcttac atcagatgca tcgtgaatac cactttcaga aatataatga
     5581 tgattgggtt ttttattttc taaaatagta tttgtatgtt ccacatttgt gacaaatcgt
     5641 tttaagtccc tgttatttac accaatcaat ttagcattaa ccttataggc acgttctaat
     5701 tcatggcgat catgtacttc aattaacact tctagatttt gcgatatagc gtagttatat
     5761 aaatctttca attgtttatc cgataagatg ttaacgatca ataaaatcat agatgcacca
     5821 gcttgtttag caacatcaat ttgaagcggg tctataataa agtctttgca taatacgggt
     5881 aatgttgttt ttgttgtcaa tgcttgtaat ctttcaaaac taccaccaaa gtacttttca
     5941 tcagttaaaa tggacacggc atttgcaccg tacttttcat aatctgagat ttgttgcgat
     6001 aaatctcgtt caggtaagtc attaactgta ggactcttcg atttaatttc tgcaataatt
     6061 gctagctttg gttctttctc aattgcgttt ataaaagatt ttttattctg aatcttcaca
     6121 cttttcaagg tattaagttt gtcttgataa tagccatttt gtaaaagtga ctgtttatat
     6181 ttaacaattt ctgctaaaat cgtcatatta ttcacctctc atttgatggt attttttcaa
     6241 tgcttcacca ttatcaatca atgtagttgc aagttctatg ccttctgcga tggtatccac
     6301 tttctctgca acataaaggc ttaaacccgc atttagtaag acaacatcac gtcgacttga
     6361 ctgatcttta ccattcaaga tattaaggga gattgctaaa ttttcttcag gtgaaccgcc
     6421 tttaaaatca ctattcggcg catgtttcaa accataatca gtcgcattta atgtgtaatt
     6481 tttgatttct ccatcttcag tcaattcata tatcaaatta tcaccagata gtgttgcttc
     6541 atccatacca tttgcaccat gtaaaacgat tgcacgtttt ctacctaaat ctttaatcgt
     6601 tttagcaact aactttaact ttgtaggatc aaagacgcct accatttgat acgttaagtg
     6661 atatggatta attaatggac ccacaaggtt taatattgta ggctttccaa tcatttttct
     6721 aactggttgc atatacttca tgattggata tgattcagtt gcaccaatga atacaaggtc
     6781 tttttcattt aattggttag gtgtatcatc aacagttgtt gtttgtatgt tcatttgatt
     6841 taacaaatcc gtactacctg aatttgaggt aatactttta ttaccatgtt ttataacttt
     6901 tacgccagca cttgctacaa caaaagcaac agtcgttgaa atgttgaaac tatttgactt
     6961 gtcaccacct gtgccgcaca cacacatagc cccttcataa catggttgat gtggatacat
     7021 tgtattaatt aagctacgta caatatatgt taattcttgt tgttggattt ctcgctccga
     7081 ataggaacta agtaattcat atttaatatc agttccaata ctaggagaaa taagtatatc
     7141 gattagctct ttaatgtcgc tttcaagtaa tatagtttca gtttttattc ttgttagtaa
     7201 tgtcatggtt ttcatccttc cttcactaga ttaatgaaat ttgtaattat tttgacacca
     7261 tagtctgtag caaatgattc aggatggtac tgaataccgt aatgcggtct ttctttatgc
     7321 tcaaatgact gtatacaatc ttcggtacgt ccagtaattt tcaattcttc tggaaaattg
     7381 tcagggttac ttattaatga atgatatctc ataattgaaa actgttctgg tatatcttga
     7441 tataacagat gttgatgatg cgatataacc tttagtgtat caacttttcc gtgcataacc
     7501 ttgtcgcctt taatgacttc tccaccgtaa taacaagtca gtgcctgagc acctaggcaa
     7561 atacctaaaa tgggtttgtg ttgataggtt gatatgattt tcattaactg ttgatcgtct
     7621 aatggatgcc ctggaccagg agatataata acagcgtcca ccgattgatt cagcacatta
     7681 tcatcatcag gatattgaac aatgacgtca gtatgttgag caacaatatc cactaggtta
     7741 tatgtaaagg aatcataatt atctacaact aagatcatgg cctcacctcc aataagcttt
     7801 tagctttcaa tttcgtttca ttcagttctt tttcaggaat agaatcatat acaacgccac
     7861 aaccagcttc tacgttgata tactgctcat ctatcatcat cgttcgaatt gctaaagcaa
     7921 aatctaagtt atgattacaa tttatgtatc caacaccacc actataaacg cctcgtttat
     7981 gtggatattg ttcatatatt ctttcaattg cacgtaattt tggtgcacct gaaacggtac
     8041 ctgttggtaa taaattcgca ataactgtca ttggtgataa attttgattt attttacctg
     8101 tgatttcact tacgatatgc ataacatgtt catatttttc aataaccatt aatttagtaa
     8161 tttttgaggt accgatttta cttactctat gaatatcatt acgtcctaaa tcaactagca
     8221 tacgatgttc gctgcattct tttggatcat taagtagttg tttcatattc tcattatcta
     8281 tttgtgtcgt ctcaccacgt tgaatcgtac ctgcaatagg attagttgtt acaatttgat
     8341 ctttgacact tacgaaactt tcgggagaac taccgacaat atatggttga tcgatattaa
     8401 gataatacat atatggactt gggttttgtc gttttaaatt ttgatacagt tgaaacgaaa
     8461 gttgatttaa atgctgacta gcatgatgcg catatttgta aattcttgat ggcacaactt
     8521 ggaacatatc cccttctgtt attttctctt tgaaatactg aatcatttcg ataaatcttt
     8581 cttcagaaat atttgattga atttctttag ttttaaaatc aaaatcttgt gtaggcatga
     8641 atggttggat tttagttaag tcttcgatag acttattaac tcgattctca agatctgatt
     8701 ttgttgaatt tgaaaattga ttcgtcgcga tgatatataa ctcatctttg taatggtcaa
     8761 atacataaac ttgttcaacc atatataacc ttacatcgtg ctgcttgtga tcttctaatt
     8821 gtattgattg caatttagga aattcatgtc ttactaaatc aaagctacac gtcccaacat
     8881 atccagatat aaacggtaat gacttaagtt gctcatcttg aatattatgg tagtcttcat
     8941 ttattttagt cgttaaataa tggtacggtc tttcaatgat ttgatacgat tcttttaaag
     9001 tgcttactga taatacatca ttatctaaag ttaaagtgcc ataaatatca aaaataacaa
     9061 ctgaatagcg acctttagtt tgttgttgat ttgtactttc caaaatgatc ttcttggaat
     9121 gaagttgtgc taaaacttcg ggcgttacat ttgcttttat ttttttataa aatatatcca
     9181 ttctatacgc tcctttcaaa aaagcgccag catccttatc aatataaagg acgctgacgc
     9241 gtggtaccac ctaaattaac cgaatattca aaatattcat agttcactct ttactatata
     9301 taatttttct gttgcagaca aaacccaatt tcattaatct cggtgttagt tcacatcatc
     9361 cactaacttt ctgttgctac ctttaattaa ctactacatt ttgtctaaat aaaaagacac
     9421 cacataacgc atatacctgt aaggacgcgt taccgtggtg ccaccttagt taacataatt
     9481 catgttcact ttcaaaactc attcaattgt tttccaaagt ccaattcaca agatatggcg
     9541 tgctaattcc catcacccat tagctttcta tttgctacgt ttcatatctg ctactatttc
     9601 tttagaaaat tctaattatt tttatagttc attatattac ataggtcgtt cacatttgtc
     9661 aacactaatt gtttactcaa ttggtgataa gcaatatgca tatagtaatt tctctgtcgc
     9721 tttaatagaa tcaatatgtg ttcgttccat tgcatgagat gattcaatgc cagcgccaaa
     9781 taaaccatgt ctgatatccg caccagcatg taaagctgct gaagcatctg aaccataata
     9841 tggatatatg tctactttat atggaatgtt atttattttg caaagattaa ctaggtgcga
     9901 tttcaattgc ttatgatatg gacctgaagc atctttggca caaatagaaa ctgtatattc
     9961 atccgatgct tgaccgtctc ccaacgcgcc catatctaat gcaatatatt ctttgatttt
    10021 cgaatcaatt gatgcatttg caccgtaacc tatttcttcg ttattagaaa tataaaattg
    10081 cgttgtatgt ggtaatatta tttgctcttc ttttaatttc tttagtaatt gtagtatcat
    10141 cgctacgcta gctttatcat ctaaatgacg agatttaata aaacctgatg acgtgataac
    10201 tgtacgtgga tcaaagctaa caaaatcacc tactgaaata cctaaactct ttgtatcttc
    10261 ttctgatgta gttacttcat caattcttat ttccatatgc ttttgatctc taggtatttc
    10321 atgattattt ctatatacat gaacacttgt ttcatgcaga caaattgttc ctgtatatat
    10381 ttgaccagca tcagttttaa tttggcaata ttcaccctca atcgcgttat acgtgaatcc
    10441 tccaattaat tctattgcta agcgaccatc ttctttaatt tctttaacca ttgcacctaa
    10501 agtatcaaca tgagcagtaa tacagcgttg tacttcatca tttttgcctg gcactgttat
    10561 taataacgca cctttatttg ttagtgttgt ttgataaccc aagtcttttg catatttttc
    10621 gacaaattga attgcttctt ctgtgtctcc tgaaggacta ttaatacctg ttaatgtttt
    10681 aatcatttct aatattggtt ccattgattt acccctccgt tgccattgtg ttactatact
    10741 ctttattgta gatgatttat ctccgtttat ctattaatgc tattatcgat ttttatttac
    10801 tattgcactg tgtcaacagc tcatttacaa tgttattatt ctgaaaattt cgaaataagg
    10861 tgatttatat gacaacagtt ttatttgttg gacttggatt aattggtgga agtcttgcta
    10921 gcaatataaa ataccataac cctaatacta atattattgc atacgatgca gatacttctc
    10981 agttagataa agctaaatca atcggcatta ttaatgaaaa atgtttaaat tatagtgaag
    11041 ctattaaaaa agccgatgta attatttatg caacacctgt tgctatcaca aataaatatc
    11101 ttagcgagct tatagatatg ccaactaaac ctggtgttat tgtttctgat actggtagta
    11161 ctaaagcaat gatacagcaa cacgaatcca atttattaaa gcataatatt catttagtca
    11221 gtggtcatcc aatggctggt agtcataaat ctggtgtact aaatgctaaa aagcacttat
    11281 ttgaaaacgc ttattatatt ttagtctata atgagccaag aaatgagcaa gcagcaaaca
    11341 cgttaaaaga actgttatca cctactcttg ctaaatttat tgtaactact gctgaagaac
    11401 acgactacgt aacaagcgtc gtaagtcatt tacctcatat cgttgcatct agtttagttc
    11461 atgttagtca aaagaacggt caagaacatc atttagttaa taaacttgca gctggtggtt
    11521 ttcgtgatat cactcgtata gctagtagta atgcacaaat gtggaaagat atcaccttga
    11581 gtaataaaac gtatatttta gaaatgattc gacagctaaa aagtcagttt caagatttag
    11641 aaagactaat tgaaagcaat gattctgaaa aattgttatc attttttgcc caagctaaat
    11701 cgtatcgcga cgcactaccc gctaaacaac taggtggact aaatactgcg tatgatctat
    11761 atgtagatat tccggatgaa tcaggtatga taagtaaagt gacttatatc atgagtttac
    11821 ataacatatc tataagcaac ttaagaatct tagaagtacg cgaagatata tacggtgctt
    11881 taaaaattag tttcaaaaat cctactgacc gagaacgcgg tatgcaagca ttgagtgatt
    11941 ttgattgtta tatccaataa ttattaagtc tcttttgata aattcccatg tattcttaga
    12001 tattattgtg aaatctattg tgatatatga aatatttatc tttagagact tattttatac
    12061 gaatcacagt tatatattcc ttaaaccgta tagtcattac attttatgtc cagccattaa
    12121 acctaatcta ccatgttttg tacctgcttc tgtaaacgat actgctttgg acacaatacc
    12181 tttgccgtat ttcaaatgta attggtctat cgttttagct aggcattcgt cacgtttgcg
    12241 ttggtattca tcttcaaaca gacttaactg tcgctcatcc tcattaataa attgactcaa
    12301 agatatactt agcgtacgat atagtgcttg tttattacat aatttatctg caaaatgcat
    12361 tactacttta taaatatctt tttctaagtt tgttggatct ttcaaagtat attgcttatg
    12421 tacaccgcct tcatcactat agccaaaggc aaaatgtatc gttcttgcca ctttttttct
    12481 tgctcgaact ctgctagcaa catcttcaat taactcttgc attactactt ttgcttcatc
    12541 aaaatgataa tctctcatta atatttgact tttgcatatc gatggattgc tgatcttgtg
    12601 cttttcacgt actttactct gatctatccc attcgcatgt agatgcatat caacacctaa
    12661 aataccgaac tcttttttta aaaatttata tggatatttc gctaaatctc ctatagtaaa
    12721 aattcctctt ttattcaatt tggcttctgt tcgacgatta ataccccaaa aatctcgcaa
    12781 gggctgaatt ggccataatt tcgttggtac atcttgatat cgccattcag ctataccatt
    12841 ttgactatgc ttcgcttcaa catccatagc aattttactt aataacatat tagaaccaat
    12901 gcccacagta caataaatgc ctgtttcttc ataaatttca cgtttaagtc tttcgcaaaa
    12961 tgcatgtact gtagaactaa atctatgata gctatcagta acatccataa aaaattcgtc
    13021 aatactatat tggtgtaaat cttcaggtgg aatataacgc aatgcaatct tagaaatagc
    13081 aactgaaaca ttaagatatt tacgcatact tggattgata atgtaaatat catttctatg
    13141 tggtatttca aacaatcgcg accctgtctt gatgcctaat tcttttaatt taggtgtcgc
    13201 agccaatatt acagaaccct gacgcttagt atctgcaaca acagctaact ttgtttctaa
    13261 tggatctagc cccttttcaa tacaagaaac actcgcaaaa aaactttttt ggtcaataca
    13321 tagaacatcc ctatcttcta ataaatgata attatacact gttattcctc ccttacttga
    13381 accttattat atacgaacac gtgttctatt tcaactattt tagaacaaat gttctgttat
    13441 tttgcaaatg aatttttaag tattacatga tatactcaaa ttaataatga ttaggaggtt
    13501 tggatgatgc caatcgtcaa tgtaaaatta ttagaaggtc gttcggatga acaattaaaa
    13561 aatttagtta gcgaagtaac tgacgccgta gaaaaaacaa cgggggcaaa tagacaagca
    13621 attcacgttg ttatagaaga aatgaaacca aaccattatg gtgtggctgg cgtaagaaag
    13681 tcagatcaat aattcttcat aagatgcatg ccaattaatt ctttgaaaac gaacaaggcg
    13741 acttctatct gagtatgata gaaatcgcct tgtttatttt taatcttcat ctaaaaagtc
    13801 tttaatagct tgtttatttg tgtttttatt aatctgtaat gcactaccat cagtatttgt
    13861 attgacatct tcgtatgagt tcttgattgg cacagtcaat gacttaacat ctttttcacc
    13921 tcggatgcca aaactcaaac ctgtttggaa aatccctgaa tcaggaatgt ttgtattcac
    13981 atagtctctt aaaatacctg caacttttgg taatttaaca actgttctaa aattaaccat
    14041 ttcttttttc aatgtttgca tcacttgttg ctgacgtcgc acgcgtccga agtcaccttc
    14101 agggtcgtga cggaatcttg cataaccaag taattcttta ccattcaacc tatggttacc
    14161 ctttttcaaa gatacaccaa tatttttcga catatccttt tcgacattaa ttggtacacc
    14221 ttctggcatt aattcatcaa tcattttctc aaatccagta aaatcaacta ctgcataata
    14281 ttcaggatta attcctaaat ttttatcaag tgtttttcta agtagctctg gaccacctaa
    14341 agcgtatgct gaattaattt tgtgttttcc atatcctgga atatctgcat aaatatcacg
    14401 catgacagac atcattttca tttttttatt gataaagtca tattgaacaa ccatgataga
    14461 atctgttctt gattgtccac cttgtgcttt atctgcaccg agtacaagaa tagaaatttt
    14521 accatcattt tttactggtc cattaaattg atgtacttta acatctttcg catgtttctt
    14581 ggcatattct acaccgctat tgtaactatg tacaatatat acaactaatg cgataagtaa
    14641 aattacaaca atcagaagaa tgataggtaa tttcctaatt ttcttcttct tttttcgctt
    14701 aggcgccgaa gtgcgatgtt cactttgacg tctatattcg ttgtcattag tttctttatc
    14761 catatttacc taccttatat cttcaaaaat agatttttgt gtactataat aatcacatat
    14821 taacgttata taaaaacaat tcaaaaagca agtgatttct taataaatcg tactaaggtc
    14881 taatgaaagg atgtcaaaaa tgaatattaa tacagcttat tttgccggag gttgcttttg
    14941 gtgtatgacg aaaccatttg acacctttga cggcatagaa aaagtaactt ctggatatat
    15001 gggcggacat attgaaaatc ctacttacga acaagtaaaa tcaggtacga gtggtcattt
    15061 agaaactgtt gaaattcaat atgatgttgc attattctca tacaataagt tattagaaat
    15121 atttttctca gtcattgacc cattagatac aggtggtcaa tatcaagacc gtggtcctca
    15181 atatcaaaca gctattttct acactaatga tcatcaaaaa gaactcgctg agacatatat
    15241 cgagcagctt aaaaatacga ttaatgctga taaggcaatt gcaacaaaaa tattaccagc
    15301 gtcacaattt tacaaagccg aagactatca ccaagatttt tataagaaaa atccagagcg
    15361 ctatgcagaa gaacaaaaaa tacgccaaga atacaaaaat aagcaataac atttatactt
    15421 gatgaaactg attgggctga taataaaagt taggcgactt aacttaagct catttcaata
    15481 ttaaaatacg gtacagatag gaaacttaaa tattcttatc tgtaccgttt tttataaatc
    15541 attctttata gaaaccaaaa aatccaagcg cttcaggcat aactgtatac ctcttagcac
    15601 ttggatttta attatttgtg acgtattaca cgcattactt tagaaagtga ttcccaaagc
    15661 gaattatctt tacgataaac taaaaagcgt ggttcccaat tcggattata tttagattta
    15721 taacgacgta atccttggaa acgatataga ccgttgaaat gttcaaagac acggcctgca
    15781 agtcgttctc ttaaatatga ataatgcaat tgaccaacgt tcgataacgt tgccataccc
    15841 atattaaatt ttgtataacc ttgttcttta ctccaaagta acatgtgcaa gtataatcca
    15901 tccattaatg gtaaatctaa ctctggcaac catctaatta aatcgactga aatggcatca
    15961 ttaaagtatg ttggcattaa actacagaat gcaattactt cattttcttc atttcgcatt
    16021 acaccaattg gcgctttaga taagtattct tcattaaatt gacccacaga gaaatgcatt
    16081 tcctgacgat tatctagcca taaatcactt acatgttgaa gctcatttat aaattcagtt
    16141 gaaaacggtg gttcaataat ttcgaatgaa atattaagtt catcgaattt gtttaaagtc
    16201 gctctaaatc cacggcgttt tttacctgaa gttgaaaatt gcgttaaatc aataattgct
    16261 tcttcaccta atttgaaaaa ttggttaccg aaattatgat ataaaggcat gtgttgatct
    16321 gtaacttgat agaatataac atcatagcct aaatactcag cgtaattata gaatgcttct
    16381 aacaattcat caaaggcatt ttcatcacct aacggatctc caagaaccac taatgaactt
    16441 gctttataac gatacattaa aaatgctgtt ttattttcat tagtgaaaaa ctgcttgtca
    16501 ccactatata tcaagtgact caaataatta ccgccgtact gattaataat ctcctcgcaa
    16561 tcttcaattt tagaagaaat acgtactttg ctaaattgat aatcaaacaa ccatgcaatc
    16621 atacctatga tgatagcgat gattaaaatc gtaagccaga agtaatagcg caatacagat
    16681 gtatgcattt caatcgtata aatatctaat gcatataacg ttccagcaat aaatatatgg
    16741 ttaacatata aaataaataa actgaataaa agcattgcaa ctatatttct cattcttact
    16801 gggcgtttca acctacgtgc tctacggaaa gctacaataa gcagaacaaa aataatagct
    16861 aaccatgtta ttaaaatata tgaagcgtaa gtgaagaatg tcgccactgt gattaataaa
    16921 attgaaatca tagcaaagat aatggcacgt ctactttgct tataaatacc aactacattc
    16981 agtaaaagta ataaacaagc actagtatga attgccaata gaatataata cgttaagtga
    17041 tttccatcat ataaagcatc gtaaacaatc gttaagttat ttacaaaaaa gatcatactt
    17101 gtaaagaata ctaaaattgc taatgataat gatggaattt tagcaataat atccttttga
    17161 taagacatta aaaatgacgt aacatcttta gcaggaataa agtatttaga tccctcaatg
    17221 tacttcttag ctgatgtacc aaattcaaat gatgataaaa ttaatgcaat aattaccggt
    17281 acaaaatagt acgcaaaacg atatagaagt agcattaata atactttttc ctcagggaca
    17341 cctaaagttt taaatcctag taatacaact aaatcgaaag cgccgaaacc accaggaata
    17401 aagctgacta aacctgataa tgcagcaatg ataaatattg caataaagga catgaatgat
    17461 acatgagcgt caacaattac accacagaaa tataatacaa ctgcagctgc taaccattca
    17521 acacacgaca ctaaagtgca gtacaatcct acaaaacgat tgtttttatc gggtggtcta
    17581 accattgaat aaataatgaa taatggtaag aaaaatgaca ctacatataa tacccatctt
    17641 acccatgtaa tcttatctaa gattaaagat gcatcgaaaa catggaatac aattagcaat
    17701 gataataagc ttaaacctgt caacattgaa ataagtatta aggatataaa gtgaactaat
    17761 ttctttttat catgcgtata gtttttataa accattgctc taacgcctgc accaataaag
    17821 ccaccgaaac ctacaatcgc attcaatgca ttgatgatat aacttactct taaaactttg
    17881 cctaaggata tatccatttt taaagctcta gataaaatca catcatacat tgatagaata
    17941 acaagcgatg ccccaccacc aataaatagt aacactaagg acatacggtt aatcttacta
    18001 aattcaacca acgtatcttt aaagttaata ccagataact cccgatacaa tgtgattgct
    18061 acaaaaataa ataaagctgt agcaaacgta atttttaaga ttgaaaatat tttgttttta
    18121 acttcctgat tcattttttc acatcaattc taattatttc tgttataaat caaaatatat
    18181 catataaacc ataaaaatag catatcattt acctttgatt tatataacac ttttgtcata
    18241 ttgatatctg tattaagaag taaatagaaa atatttctat ctcaaacaga acaatatggt
    18301 tatctatact gattcatatt taacataaag aaaatgatga atcaatactt atgaaaaata
    18361 ttattaatta acagccgatt atgagtgctt cttaatatat taaaaatacc acttattttt
    18421 attttcgaca taataatgaa gtactaatca agtggcaaat actcgtttca ttatgcatgt
    18481 gctttataaa cggctaaact ttcgtaaaaa tttataagct aaacatgtgc tgataatcat
    18541 aaatgtaact gcccaacatt ataagcacca taaaaaatac caacaaacat atagtcattg
    18601 gtatttttta ttacttattc aactatttta ttactttctt taatatcata ttcacctaca
    18661 tcattaccat agaaacgatt gtatcgacgt ttaaataatt ggaataaatg agtaactaat
    18721 acttttaaaa tagaatatcc cggaatacct aaaataacgc ctacaatacc aagcaatttg
    18781 cctgcacaca gtaaaatgaa aatgattgta agtggatgaa tcttaagtgt tttacccatg
    18841 atatttggtg aaatgaagtg cccttcaaca aattgtacta aagtccatac tactgctaat
    18901 tttaagagca tccacggcga tgttatagca gctattacaa tagctggaga aatcgctata
    18961 gtaggcccta aatatggtac aacacttgta actgccgcaa tactagctaa tactaagcta
    19021 tatttcaacc cgataaccga ataaccgata aacaacagta taccgataca gaatgaaacg
    19081 ataatttgtc cttgaatgta tgaaccaact tgaacactca ttttttcaag tagatcatga
    19141 aaatcttttc ggaatttcgg tggcataata ttcgttgaaa attctttgaa gtgatgtcca
    19201 tctttaagca taaagaatag tacaaatggt gttgtgacaa tcacaacgcc aatattagca
    19261 atcgtttctg caaacgttgc aattttagac ccaaagccat ctgtaaattc acttaacata
    19321 gatggtattt tcttaggtaa agaatttaac caatcattaa tttgactata atacgaagag
    19381 aaaaacgtat tatttgctat tttatcaata gaattaatta atttttctag atattgcggt
    19441 gaatttttaa ctaaactatc tacttgcgaa ccaataatag gtatcaataa attaacaatt
    19501 aacgtaataa cacctactac agctagataa ataatagaaa tacctgcaac tcttggtatt
    19561 ctataacgtt ccatcatatt tacgattggg ttaaatagat agaatagaat taaagagacg
    19621 atgataggtg ctgctatcgt cttaaaaacg atgataaaag gatcaaaaac atatgatact
    19681 ttttcgaaaa taaaaataac aatacccaac aatactagcg ctattaatga gaagactaaa
    19741 tcattcccac caacaaactt catataccgt gattcggtaa attttaaaaa attctttctt
    19801 atattctttt cattttcatt caattataga ttcaccacca cttaaaatat tcataagatg
    19861 ttgtataaaa acagtccact tatgtaaaat tactaacatc aatgatacca tacaaatacc
    19921 ctttacagca acgaaacgcc cgtgtaatac acttaattta ggattgatta atcctttctt
    19981 caaaatgatg aatgtgtaat gttaaatata taatttcaga ctcactgata ttaacatcaa
    20041 attgtttttg tatcatagtt aaaattttat atgctgtgtt atagcaaatc ggatagtgat
    20101 ttttaatcat agacacaaaa tcatcttgtg catgtatata ttcttttctt cttaatcggc
    20161 gaattaaaaa ttgtacgtgc cttataaaac gttggtattg taatgattcc ttatcaacag
    20221 ttgtcacaag gtctgattca atgatatcta tacctttttt aataacatta ttgatcaagg
    20281 tcatctcatg catagataaa tcttctgtat tagatgcaat atgtaatgca ataaatccta
    20341 tctcatcttc aggaaaatgt acatctaatg ctgcatttaa ctgatcaatc acctgtttag
    20401 caatatgata tgcatcacta tataactgca tagtttccat aacaaatgga ttgctaataa
    20461 cttgattttg ttttaagcgt ttataagcaa atataatatg atccgttaat gaaactacaa
    20521 gttgttttga atcaacattc atcgcagtat tagaaataaa attcaacgaa tcaataatta
    20581 cttgtaatac attatcatca gcgatttcaa ctaaactttt ataatgtgct ttttgttgct
    20641 cactttctaa tttataaatt ttctctattg taatagtttg gtcgtttaac gccattccct
    20701 cttttttgtt aaaaccaata cctttaccga ttaaaataac ttcttgatca ttattagtac
    20761 atactacgac attgttgttc aatgttttag taacaatata ttctcccatt atcatcacct
    20821 atttttctat tattaagatt atatatcgga aatgtctaac ttgaaagtat a
//
LOCUS       DAPDIM010000051        20098 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000051 DAPDIM010000000
VERSION     DAPDIM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 20098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20098
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.051"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(55..128)
                     /locus_tag="RFE25_001997"
     tRNA            complement(55..128)
                     /locus_tag="RFE25_001997"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(94..96),aa:Gly,seq:tcc)
     gene            complement(150..232)
                     /locus_tag="RFE25_001998"
     tRNA            complement(150..232)
                     /locus_tag="RFE25_001998"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(197..199),aa:Leu,seq:gag)
     gene            complement(879..1334)
                     /locus_tag="RFE25_001999"
     CDS             complement(879..1334)
                     /locus_tag="RFE25_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HDU2817040.1"
                     /translation="MNNDKLQRMVENLSEEKFGRTFRHCAYFNKRLRTTGGRYLLKSH
                     DIEINPKQYEHYGEDAVVKIILHELCHYHLHIAGKGYQHKDQDFKRLSQQVGAPRFCN
                     SIESYQQRANYEYYCTKCHAKYIRIRKVDTNRMRCGHCNGKLRMKRQLK"
     gene            complement(1327..3477)
                     /locus_tag="RFE25_002000"
     CDS             complement(1327..3477)
                     /locus_tag="RFE25_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDU2817041.1"
                     /translation="MDNQLINSIIEKYQFSKKQIEAVLTLLEEKNTVPFIARYRKEQT
                     GGLDEVQIKQIDDEYQYMVNLQKRKEEVIKNIEQQGLLTEELKKDILKQNKLQRVEDL
                     YRPFKQKKKTRATEAKRKGLEPLAIWMKARKHEVSIEEKAQQFINEEVQSVEDAIKGA
                     QDIIAEQISDNPKYRTKILKDMYHQGVLTTSKKKNAEDEKGIFEMYYAYSEPIKRIAN
                     HRVLAVNRGEKEKVLSVKFEFDTTSVEDFIARQEINHNNVNRSYILEAIKDSLKRLIV
                     PSIEREIHADLTEKAENHAIDVFSENLRNLLLQPPMKGKQILGVDPAFRTGCKLAVIN
                     PFGTFIAKGVIYPHPPVSKKEAAEKDFVQMVKAYDVQLIAIGNGTASRETEQFVADLI
                     KKHQLPVQFIIVNEAGASVYSASEIARDEFPDFQVEERSAVSIGRRVQDPLSELVKID
                     PKSIGVGQYQHDVNQKALENALTFVVETAVNQVGVDVNTASSSLLQYVSGLSSQIAKN
                     IIAYREENGAIKHNKELSKIKRLGAKTFEQSIGFLRIVDGSEPLDNTSIHPESYKVTY
                     QLLDKLGFGGNDLGSDALKAKLNSLDMDELAIELQVGVPTLEDIIKSLKAPNRDPRDE
                     FDTPILKSDVLSIEDLKEGMKLSGTVRNVVDFGAFVDIGVKQDGLVHVSKLSKKFVKN
                     PMDIVSVGDIVDVWVYSIDKNKDKVSLTMIDPHE"
     gene            complement(3911..4681)
                     /gene="sigB"
                     /locus_tag="RFE25_002001"
     CDS             complement(3911..4681)
                     /gene="sigB"
                     /locus_tag="RFE25_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor SigB"
                     /protein_id="HDU2817042.1"
                     /translation="MAKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIE
                     SLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDK
                     TWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIANRLEVSEEEVLEAMEMGQSY
                     NALSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCT
                     FIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQEAAHK"
     gene            complement(4656..5135)
                     /gene="rsbW"
                     /locus_tag="RFE25_002002"
     CDS             complement(4656..5135)
                     /gene="rsbW"
                     /locus_tag="RFE25_002002"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001190828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma B factor RsbW"
                     /protein_id="HDU2817043.1"
                     /translation="MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAK
                     IAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPY
                     DKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS"
     gene            complement(5137..5463)
                     /locus_tag="RFE25_002003"
     CDS             complement(5137..5463)
                     /locus_tag="RFE25_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019468012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma factor antagonist"
                     /protein_id="HDU2817044.1"
                     /translation="MNLNIETTTQDKFYEVKVGGELDVYTVPELEEVLTPMRQDGTRD
                     IYVNLENVSYMDSTGLGLFVGTLKALNQNDKELYILGVSDRIGRLFEITGLKDLMHVN
                     EGTEVE"
     gene            complement(5582..6583)
                     /locus_tag="RFE25_002004"
     CDS             complement(5582..6583)
                     /locus_tag="RFE25_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PP2C family protein-serine/threonine
                     phosphatase"
                     /protein_id="HDU2817045.1"
                     /translation="MEEFKQHYKGLIDESLTCQDKVELIKKCEKYTDEVIRKDVLPED
                     IVDIHKNYILTLNLTREDVFKTLDVLQEIVKGFGYSYRDYQRLVDKLQVHDKEIDLAS
                     SLQQTMLKTDIPQFDSIQIGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPA
                     ALAMSMIKFGMDSYGHSQLPSDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCS
                     SAGHEPGYIYRAEKEEFEEISVRGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEA
                     RNSEGTFIDKQKLLEYIKKHKHMHPQDIVQIIYEAILKLQNPNKKDDMTILIIKRVN"
     gene            complement(6933..7295)
                     /locus_tag="RFE25_002005"
     CDS             complement(6933..7295)
                     /locus_tag="RFE25_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDU2817046.1"
                     /translation="MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVA
                     AITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTYLSDDKMKEV
                     DNALMISLGLNAVAHQKN"
     gene            complement(7292..7462)
                     /gene="mazE"
                     /locus_tag="RFE25_002006"
     CDS             complement(7292..7462)
                     /gene="mazE"
                     /locus_tag="RFE25_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HDU2817047.1"
                     /translation="MLSFSQNRSHSLEQSLKEGYSQMADLNLSLANEAFPIECEACDC
                     NETYLSSNSTNE"
     gene            complement(7547..8695)
                     /gene="alr"
                     /locus_tag="RFE25_002007"
     CDS             complement(7547..8695)
                     /gene="alr"
                     /locus_tag="RFE25_002007"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDU2817048.1"
                     /translation="MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYG
                     LGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVA
                     LTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQL
                     VFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAI
                     RPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTT
                     IALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDN
                     HRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK"
     gene            complement(8761..9120)
                     /locus_tag="RFE25_002008"
     CDS             complement(8761..9120)
                     /locus_tag="RFE25_002008"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDU2817049.1"
                     /translation="MIHGIGVDLIEIDRIKVLYSKQPKLVERILTKNEQHKFNNFTHE
                     QRKIEFLAGRFATKEAFSKALGTGLGKHVAFNDIDCYNDELGKPKIDYEGFIVHVSIS
                     HTEHYAMSQVVLEKSAF"
     gene            complement(9124..9615)
                     /locus_tag="RFE25_002009"
     CDS             complement(9124..9615)
                     /locus_tag="RFE25_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HDU2817050.1"
                     /translation="MRDYNFMSPHAKKVMRLSAVLFWIPIALVLLIAFNILNWLFWEI
                     LDNNISIVSSVIIILLVAVFTLVIAPVYRYKHCRYAFEKHHLRVRNGILFLDEKVIPY
                     FRIQNIDIDVGPIMRRYRLATLTLYTAGGQAEIELIDRSEARRLKRWLNNERHLENNK
                     NEE"
     gene            complement(9602..11185)
                     /locus_tag="RFE25_002010"
     CDS             complement(9602..11185)
                     /locus_tag="RFE25_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HDU2817051.1"
                     /translation="MSEPQKLHPISYFNGIINAIKQNIVVFFIFIIFQLKDFDYTNPE
                     SYLWIGIVFVFFLISYISQIVGIMNTRYWIEDNYFILTTGIFNKKRKELNIKRIQSVD
                     MTQGVVNQIIGGVDLQIKTPSDGIVLSVISKKQGEYLERYIDQLQTELKTEVAQKSSA
                     EKNDNCNHDIEGNVEDIAEGRLDEVQNTDSMLNQKNKRIPIYQMNFKESLFMAMTSGA
                     IGVTLAALVPIYGAVRELIPWSKLNHEISQWVQIVSISVLIIILLVLIVAYIIGTIIT
                     MIRFYGFSVMLENEQLKIEYGLFNKKKVTVPTKRLQAVVERQSYIRRLFGYTAIHFII
                     TSDFENKKIEDDDNDSGSVPILPFIKRDKAYQIIQNLVPDLSYQQVNEGMPLSGFHRH
                     FLIPSIIVIAMAGIGCYFWNQLLLLFTIITIVIIGLFVIKGYLYVKHAGFKMTEEQIT
                     IQNFELLKRNIYYFKAHHIIGFDTWQHTLLKRNNLNNFSFIVAKGVGAQSINLKYARS
                     EDANKLKSWYLRGENDEGL"
     gene            complement(11178..11657)
                     /locus_tag="RFE25_002011"
     CDS             complement(11178..11657)
                     /locus_tag="RFE25_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817052.1"
                     /translation="MSDYTKLTKSPKSALLYYYITNGLEFILSVAVYVIFYFIWLRFE
                     WPHYLLYILLVLGALSTLKLFIKPLWQYHCRFYKVDQLSVQYRTSFFIYKEETSRIER
                     LQYLSIKSNPISKVLNLYKVGFMTAGHTIYLPMMSHDDVKIIEARTMSNLRGVESDV"
     gene            complement(11865..12425)
                     /locus_tag="RFE25_002012"
     CDS             complement(11865..12425)
                     /locus_tag="RFE25_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDU2817053.1"
                     /translation="MNTIRNSICLTIITMVLCGFLFPLAITLIGQIFFYQQANGSLIT
                     YDNRIVGSKLIGQHWTETRYFHGRPSAVDYNMNPEKLYKNGVSSGGSNESNGNTELIA
                     RMKHHVKFGNSNVTIDAATSSGSGLDPHITVENALKQAPRIADARHVSTSRVADLIQH
                     RKQRGVLTNDYVNVLELNIALDKMKD"
     gene            complement(12445..14472)
                     /gene="kdpB"
                     /locus_tag="RFE25_002013"
     CDS             complement(12445..14472)
                     /gene="kdpB"
                     /locus_tag="RFE25_002013"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDU2817054.1"
                     /translation="MHHVNKYFNQTMVIEALKMSFYKLNPKQLIKNPIMFVVEVGMVL
                     TLILICFPDIFGTSYLSRGYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQS
                     NLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESA
                     PVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIAL
                     FTLLTTLTIIFLVVIVTLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGM
                     DRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMLEKLIVAA
                     YMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKPFTAETRMSGIITNEISVFKGA
                     PNSMINLVKQQQGNIPLNIESLCMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVE
                     RFTELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIV
                     AMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMT
                     RGALTTFSLANDVAKYFAILPALMMSTIPEMTSLNIMHLSSPKSAIISALIFNALIIV
                     ALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV"
     gene            complement(14491..16167)
                     /gene="kdpA"
                     /locus_tag="RFE25_002014"
     CDS             complement(14491..16167)
                     /gene="kdpA"
                     /locus_tag="RFE25_002014"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit A"
                     /protein_id="HDU2817055.1"
                     /translation="MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCF
                     KIIGTDLEHMSAKTYVKHFLAFNGFMGFITFVLLIVQQWLFLNPNHILNQSIDLAFNT
                     AISFLTNSNLQHYNGESDVTYLTQMIVMTYLMFTSSASGYAVCIAMLRRLTGLTNIIG
                     NFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASL
                     ESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKR
                     VHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSAL
                     FTVITTAFTTGSVNNMHDSLTPIGGLGPMVLMMLNVVFGGEGVGLMNLLIFVLLTVFI
                     CSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILNLVFSALAFMIPGASESITNPSFH
                     GISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVN
                     KKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK"
     gene            complement(16191..16301)
                     /gene="kdpF"
                     /locus_tag="RFE25_002015"
     CDS             complement(16191..16301)
                     /gene="kdpF"
                     /locus_tag="RFE25_002015"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDU2817056.1"
                     /translation="MLLCCKEVMAMLIVLLLVVIALVLYLFYALIRSEKF"
     gene            16439..19096
                     /locus_tag="RFE25_002016"
     CDS             16439..19096
                     /locus_tag="RFE25_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDU2817057.1"
                     /translation="MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNV
                     DIKIGYIEPHQRDETNALAEQLPKITTNFTKHGSHHFQYLDVDRIIEESPTIVLIDEL
                     AHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY
                     FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVA
                     DLMSDKEKVRHNHKTSLKPHIAVAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFE
                     KNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRN
                     KWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMIL
                     IQIICVMMGLWIYQLDKHESSTIILMIFLIGIILLSIWTRSFIIGFLAAIINVFVFNY
                     FFTEPRYTFEVYRFDYPITFIVSILTSILTSALLKQIKFQYSITKKQLYRTDLLFQFN
                     DSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTTQQHEQA
                     LSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESM
                     LNELSLAVENVTLLKQTRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSH
                     SKDMSIIEKEQLLVHSFQESQYLYLLVTNILSLTKLQSSNVQIKLQPYLVSELVEEID
                     MILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYA
                     SYEQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKH
                     QSNLQYKPNQPHGSIFYFNIYTDFNEGDV"
     gene            19096..19791
                     /locus_tag="RFE25_002017"
     CDS             19096..19791
                     /locus_tag="RFE25_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2817058.1"
                     /translation="MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQI
                     DKPDVILLDLGLPDKDGLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTK
                     PFNVDELRARIRVIERIAKSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSL
                     LELLSNHKGKVLTYEMILKRIYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTH
                     PRIGYQMLQWKEK"
BASE COUNT         6590 a         3744 c         2749 g         7015 t
ORIGIN      
        1 gaattaacgt tgacatattg tcattcagtt ttcaatgttc attaaaatta tctatggagc
       61 gggtgatggg aatcgaaccc acaacatcag cttggaaggc tgaggttttg ccattaaact
      121 acacccgctt atttaattaa gaattttgat gcggccgaga ggacttgaac ctccacggga
      181 tttctcccac taggccctca acctagcgcg tctgccattc cgccacgacc gcggatatag
      241 gcatttaaaa catcttcgtt tttcagaacg ttatttatta tattatgttt taaaatattt
      301 gtcaataact tttaatcgtt tttttacaat aaattaattt gtgttatcag ttgttaacac
      361 aacgctattt ataataaaac attaagaact tattgtcaac atattttata aattaaattt
      421 agaattgact gtctttcaaa tcaaagttta tttaatttgt tcttttttaa ggaacgtgtt
      481 taatcatact aactataagc tgtacagtca atagaaaagt tcaatcaaaa tgtcattaaa
      541 aatgtataat tatcttttgt gctactttaa agctttaatt gggtaaagtt tatatattat
      601 ttattactaa aatacgtcaa gatttttaat ctaatcaatt taatttcatc ctatcaagtc
      661 acaatttatg ccattaccta tatcataagt agaaaagccg agattgcgaa gtattaaatt
      721 acgacaatct cggctttaaa cattttataa acacaatttc ttcttattca attactatgt
      781 ttaccaatca aaataactca ctgataaatt ctatagaaat tccatacaac tcataaataa
      841 tcttacatat acacgaatta gctctatttg tattgtactt atttcaattg tcttttcatt
      901 cttaattttc cattgcaatg tccgcaacgc atacgattcg tatcaacttt acggatacgt
      961 atatattttg catgacattt agtacaataa tattcataat tcgcccgttg ttgatagctt
     1021 tcaatgctgt tacaaaatct aggcgctcca acctgttggc tcaatcgttt aaaatcttga
     1081 tctttatgtt gataaccttt accagcaata tgcaagtgat aatgacacaa ttcgtgcagt
     1141 ataattttta caacagcatc ttctccataa tgctcatatt gttttggatt aatttcaata
     1201 tcatgggact ttaaaagata acgtccgcct gttgtacgta accttttatt aaaatatgca
     1261 caatgtcgaa acgtacgtcc aaatttttct tccgaaaggt tctcaaccat tcgctgaagt
     1321 ttgtcattat tcatgtggat caatcatcgt taatgatact ttgtctttat ttttgtcaat
     1381 actgtaaacc caaacgtcaa cgatatcacc aacactgaca atatccattg gattttttac
     1441 gaacttctta gaaagtttcg aaacatggac aagtccatct tgtttaacac ctatatctac
     1501 aaatgctcca aaatctacta catttctaac tgtgccactc aatttcattc cttcttttaa
     1561 atcttcaatt gatagcacat cggatttaag gattggtgta tcaaactcgt cccttgggtc
     1621 tcgattaggt gctttcaagg atttaataat atcctctaat gtaggtacac cgacttgtaa
     1681 ttcaatcgcc agttcatcca tatccaatga atttaattta gcttttaatg catcactacc
     1741 taaatcattg ccaccaaatc cgagtttatc taataactga tacgttactt tatagctttc
     1801 gggatgaatc gatgtattat ccaatggctc tgaaccgtct actattctta aaaatcctat
     1861 actctgctca aaagttttag cacccaaacg cttaatcttg cttaactctt tattatgctt
     1921 tattgcgcca ttttcttctc tatatgcaat tatattttta gcaatttgcg aacttagacc
     1981 agacacatat tgtaataatg atgatgatgc tgtattgaca tcaacaccta cttggttaac
     2041 tgctgtttca acaacgaaag ttaatgcatt ttctagtgct ttttgattaa catcatgctg
     2101 gtattgtccg acaccaatag atttaggatc gattttaact aattcactta atggatcttg
     2161 aacgcgtcgt ccaattgata cggcacttct ttcttccact tgaaaatcag gaaattcatc
     2221 tctagcaatt tctgatgctg agtatactga agcgcccgct tcattgacaa tgatgaattg
     2281 tactggcaac tgatgctttt taattaaatc tgcaacaaat tgttctgttt cacgacttgc
     2341 agtaccattg ccaattgcaa ttaattgcac atcatacgct ttaaccattt gtacaaaatc
     2401 cttctctgct gcctcttttt tagaaactgg tggatgcgga taaatcacac cttttgctat
     2461 aaaagtaccg aatgggttaa tgactgctaa tttacaacct gttctaaatg ctggatctac
     2521 gcctaatatt tgtttacctt tcattggagg ttgcagtaat agatttctta agttttcact
     2581 aaaaacatct attgcatgat tttcagcttt ttcagttaaa tcagcatgga tttcacgctc
     2641 tatcgaaggg acaattaagc gtttcaagct atctttaatc gcctctaaaa tataactgcg
     2701 atttacatta ttatgattga tttcttgacg tgcaatgaaa tcctctactg atgtcgtatc
     2761 gaattcaaac tttacagata atactttctc tttttcacca cgattaacag ctaaaactct
     2821 atgattagca atgcgtttaa ttggctcact atatgcatag tacatttcaa aaataccttt
     2881 ttcatcttca gcatttttct ttttagatgt agttaacaca ccttgatgat acatatcttt
     2941 taaaattttt gttctatatt taggattatc tgaaatttgt tccgcaataa tatcttgtgc
     3001 acctttgata gcatcttcaa ccgattgcac ttcttcattt ataaattgtt gtgctttttc
     3061 ttcaattgag acttcatgtt tacgtgcctt catccatatc gctaatggct ctaacccttt
     3121 acgtttcgcc tcagttgccc ttgtcttttt cttttgttta aaaggcctat ataggtcttc
     3181 aacacgttgt aatttgttct gttttaaaat atccttcttt aattcctcag taagtaatcc
     3241 ttgctgttct atatttttga taacttcttc tttacgtttt tgtaaattga ccatatattg
     3301 gtattcgtca tcaatttgct ttatttgaac ttcatctagt ccaccagttt gctcttttcg
     3361 atacctcgca ataaatggta ctgtattttt ttcttctagc agtgttaata ctgcttcaat
     3421 ttgtttttta ctaaattgat atttctctat gattgaatta atcaattgat tgtccattta
     3481 cttaacccac actttttctt aaatttactc atttatttta acatattcta aaatacttct
     3541 attaaggtat gatacttaat gtaattttca cttccaaaac atttaaaacg aattattagg
     3601 tcatactata ttttaaaacg cactaagatt attgaaaatg acacaccatc atttctaaat
     3661 ttcataatct aagactactt tttttattct aatagcaatc cacctattta aaacgacaat
     3721 tagatatctt cttcacttaa attattaata ctatatcgcg acatttatgt ggatacacat
     3781 taaactacgt taataatgta ttaattcgaa aatcttaatt aaattaaaaa tacccctcga
     3841 tttcaattta ataatcaagg gataattata tggatttttc attataaaac gtatcattaa
     3901 taagcaaatt ctatttatgt gctgcttctt gtaatttctt aattgccgtt ctctgaagtc
     3961 gtgatacatg catttgactt aaaccgatac gctcacctgt ctctttttga ctcaatcctt
     4021 caataaacgt acattgtatg atttctcgtt cgcgatcaga taatataggt aatatttttt
     4081 ctaaaatcat acgtttttca gttaagtcat aatggtcatc ttgttgcccc ataatatcta
     4141 atagcgtaac agttgaacca tctttatcag cttcaatgga atgatcaaca cttaacgcat
     4201 tataactttg tcccatttcc attgcttcta acacttcttc ttctgagact tctaatcgat
     4261 tagctatttc actgatagaa ggtgaacgct ctaattcagc ggttagttca tcgctcactt
     4321 ttttgattct tggcccaatt tctttaatac gtctcggaac atgtacactc caagttttat
     4381 ctcgtagata tcttttgatt tcaccgatta cagtaggtac taaaaaggct tcaaacttcc
     4441 gttcaaagga catatcgaat ctatttatgg cacctattaa accaaccata ccaacttgaa
     4501 ctaaatcttc gtgatgtgat tgtcctttag aatatttata tgccaatgac tcaattagtt
     4561 tttggtaatg tttaactaac ttatcctgtg catctgtatt cttattttct tggtgttctt
     4621 taatccattg gttaatttgc tcaggtgaaa cttcattagc tgatttcgac tctttcgcca
     4681 ttatttcgca cctgctcttt ttttatatac ttagtcatac tgattgtcac accagattct
     4741 ttatatactg tgacttcatc cattaaagat tcgattaaaa ataaacctag gccaccttcg
     4801 cgtaaaaagt ctatattttc gtctttatcg taaggaccta tttttgattt agttgtttca
     4861 taatcaaaac tgtcaccttt atcagaaata acaattttaa ttttatcttc taaaatttca
     4921 aaatatatgt taataatgcc cacattgtta ttttctttgt atgcatgttt aactgcattt
     4981 gtcacagctt cactaactgc aatcttggca tcttcaatat catcatatgt agcaccagct
     5041 ctcgaaaaaa cgccagaaag tgttaaacga attaaactta catactctgc cgatgctggc
     5101 acgcgcattt cgataaaatc ttctttagat tgcatgttat tcgacctccg ttccttcatt
     5161 aacatgcatt aaatccttaa gaccagtaat ttcaaatagt ctaccgatac gatctgacac
     5221 acctaaaatg tatagttctt tatcattttg gtttaatgct tttaatgtac ctacgaataa
     5281 acctaaacct gtcgaatcca tataactcac attttctaaa ttaacataaa tatcacgagt
     5341 tccatcttgt ctcataggtg ttaaaacctc ttctaattca ggcacagtat aaacatctaa
     5401 ttctccaccg actttaactt cgtaaaattt atcttgagtg gttgtttcta tattaagatt
     5461 catttcatta cactcctact tattaaaaat atttatcttc attttaagcg ctgtatccac
     5521 catatttata tttcaaatta ttatataccc atcgaaataa tttctaatct tcttttttaa
     5581 attaatttac tctttttata atcaaaatag tcatatcatc ttttttattt gggttttgaa
     5641 gctttaaaat tgcttcatag ataatttgaa caatatcttg tgggtgcata tgtttatgtt
     5701 ttttaatata ttctaaaagt ttttgtttat ctataaaggt accttcacta tttctagctt
     5761 cagtcacacc atccgttaaa atgataatta aatcatcaag gtatatagga atttcttgtt
     5821 gttgatatcg tgtttgtgaa ctgattccta acactctacc tctaactgaa atttcttcaa
     5881 attcttcttt ttcagcgcga taaatatatc caggctcatg accagctgaa ctacaataca
     5941 ataaatggtt catttcttca tataaaccat aaaacattgt gacgaacata ttttgattaa
     6001 tattcttttc aacaacacga tttaaacgtt ttaagccatc actcggtaat tgtgagtgtc
     6061 cataagaatc catgccaaac tttatcatac tcattgctaa agcagctggt atacctttcc
     6121 caatgacatc tgcaacagca aagctcattg tgccatcgtt atggtcaatt aaattaaaat
     6181 aatctccact tactttttgt gctgccactg aaataacgcc aatttgaata ctatcaaatt
     6241 gtggaatatc tgttttaagc attgtttgtt gtaagctaga agctaagtct atctctttat
     6301 cgtgaacttg aagtttatct accaatcttt gataatctcg ataactataa ccaaagcctt
     6361 taacgatttc ttgtaagaca tctaatgtct tgaacacatc ttcacgcgtt aagtttaacg
     6421 tcaatatata gtttttgtga atatcgacaa tgtcttcagg caagacgtcc ttacgaatca
     6481 cttcgtcagt gtatttctca cactttttta tcaattctac tttatcttgg cacgttaaac
     6541 tttcatcaat taaaccctta taatgttgct taaattcttc cacgattagt tgcctcctca
     6601 cttcccttac aaagcaaatg cttaagcaag gataattatg attcacttac taacatttat
     6661 ttaattgcac ttatcaattt tgtcgtttgc aattttgctg tagatgatac ttttaagcta
     6721 aaaaaaactt taggatggaa tacctaaagc ctaaaaaact taagacatcc ttttataata
     6781 aaaaatatga atatcataac tggtatttgc taaaatctat gtttataaga aaattcttcg
     6841 tacagaattt agaaatagtt ataattatta taaagttatt gtcttttata tcaatatttt
     6901 atttatctct gaaaaataca tataatagac gcctaatttt tctggtgagc tactgcattc
     6961 agccctaaac taatcattag tgcattatct acttctttca ttttatcatc ggataagtac
     7021 gtcagttttt ctttcaatcg ttttttatca agtgtacgaa tttgttctaa taatataact
     7081 gagtctttat ccaatttata ctttttcttt tcaatctcta catgtgtcgg tattttcgct
     7141 ttattaatcc taccagttat tgccgcaaca ataactgtag gactatattt attaccagta
     7201 tcattttgaa ttatgactac aggtctgact cccccttgtt cagatccctg tactggtgat
     7261 aaatctgcta aataaacatc tcctcgtcta atcattcatt cgttgaatta gaagataaat
     7321 atgtttcgtt gcaatcgcat gcttcacact ctatcggaaa agcttcgttc gctagggaga
     7381 gatttaaatc agccatttgt gaatatcctt cttttaaaga ttgttctaag ctatgacttc
     7441 tattttgact aaaagataac atatgagaac ctccaattga ttccaaaagt tattaaatga
     7501 tctttaatta ctctaatgat aacaaatttt atatgcactg accatattat tttaacaatt
     7561 catttgttac aaaacgttga tcaccatcat gatagattcg cggcaaacgt ctcgacaagt
     7621 tacaaagcac ttcataatta atagtatgtt gcttttcagc taccacctct accgactgtg
     7681 gactttctct atgattatct attaaaatca ccgaatctcc agctttaact tgatctggca
     7741 ctttaacaat tgtctgatcc atacatacgc gaccaataac ttcgcattga tgaccattta
     7801 catttacaaa gctaccttgc attatgcgta aatagccatc tgcatatcca ataggtaaca
     7861 aagctattgt agttgggtca gtagctgtat aagttgcacc ataacttaca gactcacccg
     7921 cttgtagcgt ctttgtttga actacattag caattaattg cacacttggt ttaaggtgta
     7981 ctttaacttt ttgctgtaca tactctgatg gataatatcc ataaagggaa attcctggtc
     8041 ttattgcatt acagaattgg caatccatta atagagagcc tgctgagttc tgacaatgta
     8101 tatattcagg tttaattgct tcattgacca tatctttaaa acgttgatat tgttcagttg
     8161 tcatatctcc tggttcgtca gcacaggcaa agtgtgtaaa cacgccttca aatacaagtt
     8221 gctcatattg ttgaatgatt tcaatcactt cttgatacgt attagtatct ttaataccta
     8281 aacgtcccat tcctgtatct aatttaatgt gcaaccataa ctttttctct tgctcaccag
     8341 aaatgttttt aattgcttct ttcaaccact gtttagacgg aaccgttaag gcaactctgt
     8401 gttgtatcgc tttatcaata tctttagctg gtaacacacc taagactaaa attttagcag
     8461 taatcccatg cattctaagt tctatcgctt catctaacgt tgctacagca aaaaatgtgg
     8521 cgccattttc cattaaatga cgtgctactt taacactacc tagtccatag gcattggctt
     8581 taacgacagc catcactgtt ttatttggat gcaatgtact gaatactttg aaatttgatg
     8641 caacagcgtt taaatctaca ttcatatacg cagatctata atatttatcc gacatattac
     8701 ttcctcctgt aattcccaca cgttttaaaa ctagatctta attatcattg tataacaaat
     8761 ttaaaatgct gacttttcta aaacaacttg gctcatcgca taatgctcag tgtgtgagat
     8821 actaacatgt acgatgaacc cttcgtaatc aatctttggt ttgccaagtt cgtcgttgta
     8881 acagtctata tcgttaaaag ctacatgttt tcctaagcct gtgcctaatg ctttactgaa
     8941 cgcttctttt gtagcaaacc tgccagctaa aaattcaatt ttacgttgct catgtgtgaa
     9001 attgttgaat ttgtgctgtt catttttagt taaaatccgc tcaaccaatt ttggctgctt
     9061 actatataac acttttattc gatcgatttc gattaaatct acaccaattc catgtatcat
     9121 tgattattcc tcatttttat tgttttctaa atgtctctcg ttatttaacc atcgtttcaa
     9181 tctacgtgct tcacttctat ctattaattc aatttcagct tgaccacccg ctgtataaag
     9241 ggtcaaagtt gctaatcgat agcgtctcat tataggacca acatcgatat caatattttg
     9301 aatacgaaaa tatggtatta ctttttcatc caaaaataaa atgccgtttc gtacacgcaa
     9361 atggtgtttt tcaaatgcat atctgcagtg cttatatcga tatactggcg ctatgacaag
     9421 cgtgaaaaca gcaacaagta atattataat cacactacta acaatggata tattgttatc
     9481 taatatctcc caaaatagcc agttcaaaat attaaatgcg attaaaagta caagcgctat
     9541 gggtatccaa aacagcacag cacttaacct catcactttt ttagcgtgtg gtgacataaa
     9601 attataatcc ctcatcattt tcacctctta aataccatga tttcaattta tttgcatctt
     9661 cacttcttgc gtattttagg ttaatcgatt gggctcccac acctttagca acaataaagc
     9721 taaaattatt taaattgttg cgtttaagta atgtatgttg ccaagtgtca aatcctataa
     9781 tgtgatgcgc tttaaaataa taaatatttc gtttcaatag ctcgaaattc tggatagtaa
     9841 tttgttcttc tgtcatttta aaacccgcat gtttgacata aagatatcct ttgatcacaa
     9901 ataaaccaat aatgactatt gttataatcg taaataacaa taataattga ttccaaaaat
     9961 aacagccaat acctgccata gctatgacaa taatactagg tattaaaaag tgtctgtgga
    10021 aacctgacaa aggcatacct tcattaactt gttgataaga taaatctggt actaaattct
    10081 ggataatttg atatgctttg tctcgtttaa taaacggcaa tatcggcaca ctacctgaat
    10141 cattgtcatc atcttcgatt tttttatttt caaaatcact tgtgatgata aaatgtattg
    10201 ctgtgtagcc aaataatctt cgtatatatg actgacgttc aacaacagct tgcaatcgtt
    10261 tcgttggtac agttactttc ttcttgttaa agagaccata ttcaatttta agttgctcat
    10321 tttcaagcat caccgaaaag ccataaaatc ttatcattgt tataatcgtt ccaataatat
    10381 atgccactat taatactagt aaaatgatga ttaatactga aatacttaca atttgaaccc
    10441 attgactaat ttcatgattt agcttcgacc atgggatcaa ctctcttaca gccccgtaaa
    10501 tcggtactaa agctgctaac gttacaccaa tggcgccact ggtcattgcc ataaatagtg
    10561 attctttaaa attcatctga tatataggaa tgcgtttatt tttctgatta agcatactat
    10621 cagtgttctg cacttcatct aagcgacctt ctgcgatgtc ttccacatta ccttcaatgt
    10681 catgattaca gttgtcattc ttctcagcac tagacttttg cgccacttct gtcttcaact
    10741 ctgtttgcaa ttgatcaata tatcgttcaa gatattcacc ttgttttttc gaaataacac
    10801 ttaagacaat accatcactt ggtgttttga tttgtaaatc cacaccacca ataatttgat
    10861 tgacgacccc ttgtgtcata tcaacggact gaatacgttt tatatttaat tctttacgct
    10921 ttttattaaa aatacctgtt gttaaaatga aataattatc ctcaatccaa tatcgcgtgt
    10981 tcataattcc gacaatttga gaaatgtatg atattaaaaa gaatacaaat acaataccta
    11041 tccataaata tgattcggga ttcgtataat caaaatcttt caattgaaag ataatgaaaa
    11101 taaaaaagac gactatgttt tgtttgatag cattgattat gccattaaaa tatgaaatcg
    11161 gatgtaattt ttgaggttca gacatcactt tcaacccctc tcaaattcga catagttctc
    11221 gcttcgatta ttttaacatc gtcatgagac atcatcggta aataaatagt atgacctgca
    11281 gtcataaatc caactttata caaattaagc actttactaa ttggattaga tttaatcgac
    11341 aagtattgta aacgttcaat tcgactcgtt tcttctttat atataaaaaa tgatgtacga
    11401 tattgtacac ttagttgatc aactttataa aagcgacaat gatattgcca taaaggctta
    11461 ataaataatt ttaatgtact cagagcacct aaaaccaaca aaatataaag taagtaatgt
    11521 ggccattcaa atcttaacca tataaaataa aaaatgacat acacagctac actcaatata
    11581 aattctaagc cattcgtaat gtagtaatac aacaatgctg acttaggact cttagtcaac
    11641 ttagtataat ctgacataac ccctctcccc aaataaaaaa ttatacggat ttataatcta
    11701 tttcatttta tttttatatg atgataatta tagcatatgg aatatttcat gctaatttat
    11761 tcttcctaaa ggtacatcta aaaatttaat taagcagaaa gtgcttgaat tgctaaaaag
    11821 acaccatgtt ataattttat caacatgatg cctttcatct ataatcaatc tttcatctta
    11881 tcaagagcga tatttagttc aagcacattc acataatcat ttgttaacac accacgctgc
    11941 ttacgatgtt gaatcaagtc ggccactctt gaagtagata catgacgagc atcagcaata
    12001 cgaggtgctt gcttcaatgc attttcgacc gtaatatgcg gatctaagcc cgacccagaa
    12061 cttgttgcag catctattgt tacatttgaa ttcccaaatt taacatgatg tttcatgcgt
    12121 gctattaatt cggtgtttcc attcgattca ttacttccac ctgaagatac gccgttttta
    12181 tataattttt caggattcat attataatca actgcactcg gtctcccgtg aaaatatcgt
    12241 gtctctgtcc agtgctgtcc aatcaatttt gatccaacta tacgattgtc atacgtaatt
    12301 aaactgccat ttgcttgttg ataaaaaaat atttgaccaa ttaacgtgat agctaacggg
    12361 aataaaaatc cacataatac catagttatt atcgttaaac aaatactatt tcttatcgta
    12421 ttcatggtac aggctccttc ctctttacac aaaaaattgt acaatcatat ctattaattt
    12481 aatgcctaaa aacgggacga ttaatccacc taatccataa atcaacatat tatttataaa
    12541 gattctatca atgctgtaac cctttacttt tacacctttc atggcaattg gaattaaggc
    12601 aacaatgatt aatgcattga atatcaaagc tgatataatt gcagatttag gtgacgataa
    12661 atgcataata tttagtgaag tcatttctgg aattgttgac atcattagtg caggtaaaat
    12721 tgcaaagtat tttgctacgt cattagccaa actaaatgtc gttaatgcac ctctcgtcat
    12781 taataattgt ttgcctattt ttacaacctc tattaacttt gtaggattcg aatctaaatc
    12841 aattagatta gctgcctctt tagcactaat tgtccctgag ttcatagcta atcctatatt
    12901 cgcttgtgct agcgcaggtg catcatttgt accatctcct gtcatcgcaa caatatggcc
    12961 tttcgcttgt tcatctttga tgactttaat tttatcttcg ggtttacact ctgcaacaaa
    13021 tctatcaacc ccggcttctt ttgcaattgt agctgctgtt aaagcattat cacctgtaca
    13081 cataactgtt tcaatcccca tttttctcaa ttcagtaaat cgttctacaa gaccatcttt
    13141 aatcacatct tttaaataaa tcacgccaag catgacattg ttttcaatga ctattaatgg
    13201 tgtgccacct ttactcgata catccataca gagagactca atgttaagag gaatattgcc
    13261 ttgttgttgt ttgacaagat ttatcatact attaggtgca cctttgaata ccgatatttc
    13321 atttgtaatg attccgctca ttctagtttc agctgtaaaa ggcttatatg tgccatcaat
    13381 gtctttaggc agctcattta tatacatctg cttcgctaat cgtacaatac tttttccttc
    13441 tggcgtatca tcgtagattg atgacatata agcagcgact atcaattttt ccagcatttg
    13501 ttgattcact ggtaaaaatt cactagcgat tcgattgcca taagtgattg tccctgtctt
    13561 gtctaaaatc attacatcga catctccaca tacttctaca gcacgcccac ttttcgctaa
    13621 tacattgaat tgagtaacac gatccatgcc tgcaatacca atcgccgata acaaaccacc
    13681 gattgtcgtt ggtattaaac atactgttaa cgcaatgagc atcgcaatag gtaaaattaa
    13741 atgcaggtaa gatgctattg gatataacgt tacaataacg actaaaaata taattgttaa
    13801 cgttgttaat aatgtaaaaa gtgcaatttc atttggtgtt ttatttcttt ccgccccttc
    13861 aactaaggca atcattttat ctaaaaaaga tgtacccgct tcactctcaa cacgtatttc
    13921 taaccaatca gatgttacaa gtgtaccgcc aatgactcca tcaaaatcgc cacctgattc
    13981 ttttatcaca ggtgcagact caccagtaat tgcagattca tcaacggttg ctaatccatt
    14041 tattacaacg ccatcagcag ggattgtttc tccattttct acccgaatat tttgtccggc
    14101 ttttaactct gtggcgttca ctatccgata cgcaccattt tcttctatca atcgagcagt
    14161 taaatttgat tgtgcttgtc ttaaactatc agcttgcgct tttccacgac cttcagcaaa
    14221 ggcttctgaa aaattagcaa acaatatagt tattaataat atgataaaaa ttgtaatcaa
    14281 ataacctcgc gatagatagc tagttccaaa tatgtcagga aaacatatta atatcaacgt
    14341 taaaaccatt ccaacctcaa cgacaaacat tatcggattt tttattaatt gtttaggatt
    14401 cagcttataa aaactcattt tcaaagcttc tatcaccatt gtttgattga aatatttatt
    14461 tacatgatgc attttttcca tccctttact ttattttaaa gttaaaaatt caccaatagg
    14521 accaagtaat agtactggaa taaatgtcaa accacttagt aaaacgataa atacgattag
    14581 tgatacgcca aaataaggtt tatcaatcgc tattgtatat ttatcttgat ggtatgattt
    14641 tttattcact aaacttgatg caatcattaa ttgcaaaata attggtatat aacgagaaag
    14701 caacataatg attcctgtag agatattcca gaatgttgta tcatctttca gtccttcaaa
    14761 ccctgatcca ttgttcgcag cagctgatgt catttcatac ataacttgtg aaataccatg
    14821 aaaagacgga ttcgttatac tttcacttgc tccaggaatc ataaaagcaa gtgctgaaaa
    14881 tactaaattt aaaattgggt gtatgagaaa gactaagaca atacatttca tttcacgggc
    14941 gccaattggc atatttaaat attctggtgt tttaccaacc atcaaactgc atataaacac
    15001 cgtcagtaag acaaatatca ataaattcat gagtcctacg ccttcgccac caaatacaac
    15061 atttagcatc attaatacca ttggtcctaa tccacctata ggcgttaagc tatcatgcat
    15121 gttattaaca gaacccgttg taaatgccgt cgtaataact gtaaatagtg ctgacaaacc
    15181 tgctccaaac cgtacctctt taccttccat attcggtcca taaatgccta aattcgctag
    15241 tattggatta ccacgatact cactccacat agttaatgta agaattgcta taaaaatgaa
    15301 aaacattgcg acaaataata tcaacgcatg acgatgtact cgtttaccat gtctacttaa
    15361 catgcgacca aataagaaca acattgacat aggaagtaac atcatactgc ccatttctat
    15421 aaaattgctc caaatatttg gattttcaaa aggtgttgca gaatttcctg ctaaaaatcc
    15481 tccaccattc gtaccaagat gttttattga ttcaagtgat gcaataggtc caaatgcaat
    15541 atgttgaata tgtccgctta aagtccgaat cattaaatta gcatgcaacg tttgtggtac
    15601 accttgagtc atcaataaaa tactaattaa acatgataat ggtaaaagta ctcggacaat
    15661 aaaccgaaca atatcttgat aaaaattacc aatgatatta gttaatccag ttaaacgtct
    15721 caacatcgct atacaaacgg cgtaacctga tgcactagat gtaaacatta aatatgtcat
    15781 tacaatcatt tgcgttaaat atgtcacatc tgattcaccg ttatagtgtt gtaaattact
    15841 atttgttaaa aaagatattg ctgtattaaa cgctaaatct atcgattggt ttaaaatatg
    15901 atttggattt aaaaaaagcc attgctgaac tattagcaat acaaatgtta taaaccccat
    15961 aaatccatta aatgccagaa aatgtttgac atatgtttta gctgacatgt gttctaaatc
    16021 tgtgccgata attttaaaac acatattttc aaatctagta aatattaaat ctactcttga
    16081 cgattgcacc aatgctacgc gatatagata tccactaaaa acatacgtaa tcataaccat
    16141 cattgttaga aacaaaatta tttccatgat aaccctcact taatatattt ctaaaatttt
    16201 tcactacgaa ttaaggcata aaataaatac aaaactaatg caataactac cagtaataaa
    16261 acgatgagca ttgccataac ctccttacaa cacaacaaca tcgtaacaac ttgtttatga
    16321 gagaaatatt aattttcaaa cttagttatt aagaaatcat taagatgtgt atgcagaaat
    16381 aaattttata gcatttaatt gtgaagaata ttatgatatt gctatcgagg tgaaggttat
    16441 gtcaaacact gaatcgctaa acataggaaa aaagcgtgga tctttaacaa tttacatcgg
    16501 ttacagtcca ggtgttggta aaacatttga gatgctttca aatgccattg aactatttca
    16561 aagtaacgtt gatattaaaa taggatatat tgaaccgcat cagcgtgatg aaacaaatgc
    16621 attagctgaa caattaccta aaatcacaac caattttact aaacatggta gtcatcattt
    16681 tcaatattta gatgtcgacc gcataatcga agaatcgccg acaatagtac ttatcgatga
    16741 gttagcacat acgaatattt ctagagatcg tcatgagaaa cgatatatgg atattgaaga
    16801 aattttaaat catggtatcg atgttcatac cactttgaac attcaacata ttgaaagttt
    16861 aagtagtcaa attgaactga tgaccggtgt acatgttaaa gaacgtgtac ccgactattt
    16921 cataatgagc gccgatgtat tagaagtcgt agatatctca cctgaacaat taattaaacg
    16981 cttaaaagct ggcaaggtat ataaaaagga taggctagat gtagcattta gtaatttctt
    17041 tacgtatgcc cacctaagcg aactgcgtac attgacgtta agaacagttg ccgacttgat
    17101 gagtgataaa gaaaaagtcc gacacaacca taaaacgtca ctcaaacctc atattgctgt
    17161 ggcaattagt gggagcattt ataatgaagc agtaattaaa gaggcattcc atattgctca
    17221 aaaagaacat gcgaagttca ctgctattta tatagatgta ttcgaaaaaa acaggcaata
    17281 taaagatagt caaaagcaag tgcatcaaca tctcatgctt gcaaaatcat taggagcaaa
    17341 agtaaaagta gtttatagcc aaaccgttgc attaggatta gacgaatggt gtaaaaatca
    17401 agatgtaacc aaattaatta tcggacaaca tattagaaat aagtggcgag actttttcaa
    17461 tacaccttta attgaccatt taatgtcctt tgaacatagc tataaaatcg aaatcgttcc
    17521 aatcaaacaa atacctgttg aattgaaaat gaacaaatca ccctatcgtc ctaaaggcaa
    17581 acgtttcgcc atagatatgt taaaaatgat tttgattcaa ataatttgtg taatgatggg
    17641 actgtggatt tatcaacttg ataagcatga gtctagtacg attattttaa tgatttttct
    17701 catcggcatc attttattat ccatttggac gcggtccttc atcattggct ttttagcagc
    17761 aattattaac gtatttgttt ttaattattt ttttacggaa cctagatata catttgaagt
    17821 atatcgcttt gactatccta ttacatttat cgttagcatt ttaacaagta ttttaacgag
    17881 tgctttatta aaacaaatta aattccaata ctccattact aaaaagcaac tttatcgtac
    17941 agatttatta tttcaattta atgattcgat taaacaaact tatacagttg aaaacttact
    18001 aataaatgct ggataccaaa ttaatcaatt attgcaacaa tcaattacta tatacgttat
    18061 caatcaatcg aaagtaatta aaacaatacc attgcaaaac catatcgata atacgactca
    18121 acagcatgaa caagcattaa gctgggtaat taaaaatgaa agacaagctg gtgcaacaac
    18181 agatacattt ccaggcatta ataaatggtt gataccaatt ggcacatctc cgattaaagg
    18241 cattctagcc attgattacc aaagttctca agtgattaat ccatatgatg catcaatatt
    18301 agaatcaatg ttaaatgaac tttctctcgc cgttgaaaat gtgacgttac ttaaacaaac
    18361 gagagaatcc atgttacagg ctgaacgtca actgacacat tcaaattttt taagatcaat
    18421 ttcgcatgac atacgtacac cgttaacaac aattatggga aatttagata ttttagtatc
    18481 acatagtaaa gatatgtcta tcatagaaaa ggaacaatta cttgtacata gttttcaaga
    18541 aagtcagtat ttatatctat tagtgacaaa tattttatca ttaacaaaat tacagtcatc
    18601 aaatgttcag ataaaattgc aaccttatct cgttagtgaa ttagtagaag aaatcgatat
    18661 gattttagaa cgtcgccatt taaaaaagcg tataactgta tcatcctccg taaatttaca
    18721 gtttatacac attgacagta agttgatttt acaagcttta ttcaatttga ttgaaaatgc
    18781 agttaaacac acttctactg acaccaaaat caatttatct attcgttatg ctagctatga
    18841 acaaatcgaa tttgccgtta tagacgaagg acctggaatt agtttagaag aacaacaaaa
    18901 gatattcgag cctttttaca caggatcaaa taaatatttt aaagataacc aaaaagaaag
    18961 catgggacta ggcttatatt tagtacagac tatcctacac aaacatcaat caaacttaca
    19021 atataaaccg aaccaaccac acggcagtat attctatttc aatatatata cagactttaa
    19081 cgaaggagac gtataatgca atctaaaata ttgataattg aagatgatca cgcaatcaca
    19141 catttacttg atgttgcatt aactttagat tattacaatg taactacagc cgacaatgcc
    19201 acacaagcac actttaaaat tcaaattgat aaaccagatg tcattttatt agatttaggt
    19261 ttaccagata aagatggatt atgtttgatt tcagaaatca ggcaacatac tgacattcct
    19321 atcattgtaa taagtgcaag acaagaagaa caaacaatta ttcaagcttt agataacggt
    19381 gcgaatgact atatgactaa accttttaat gttgatgagc ttcgggcacg aatacgagtc
    19441 atcgagagaa tcgctaagtc acatcaagaa actaacattg tatttactaa cggtttgcta
    19501 agcatcgact ttggctccaa atctgttgtt attaataatc aggaggtaca tttgacgcca
    19561 aatgaattta gcttgttaga actattgtca aatcataaag gaaaagtact cacttatgag
    19621 atgatattaa aacgaatata tggctatgtt aataagactg aaatgcctag tttaagagtg
    19681 catatgacat cattaagaca aaaactttca caatgtcatg aggacgcaaa agatattatt
    19741 aaaacacatc cacgcattgg ttatcaaatg ttgcagtgga aagagaaata attaaataaa
    19801 aaagatcgct gccattaaac gaatgattgg cagtgatctt ttttatattc aacttattat
    19861 ttatcgcgca ctagcgtcag caaaaagccc tattgttttt tataagaaca tgatactgaa
    19921 atttcataaa gtttatttat gttcgattat tcttaattta agtagttgtt atattctaga
    19981 ttcatattta tatttacaca gaatgatata accgcataca gatctcaatc caattaaata
    20041 tttaaccttt aaaacgttag tactttgata tctacagaga atcaattatt gaaaacaa
//
LOCUS       DAPDIM010000052        20016 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000052 DAPDIM010000000
VERSION     DAPDIM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 20016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20016
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.052"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            9..191
                     /locus_tag="RFE25_002018"
     CDS             9..191
                     /locus_tag="RFE25_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817059.1"
                     /translation="MSISVGDKVFNPETNSTLEIVQLVGDIRDTHYKLSDGSIISLID
                     FVVKPIHLIKEAQEND"
     gene            184..714
                     /locus_tag="RFE25_002019"
     CDS             184..714
                     /locus_tag="RFE25_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP pyrophosphatase"
                     /protein_id="HDU2817060.1"
                     /translation="MTNTLQVKLLSKDARMPERNHKTDAGYDIFSAETVVLEPQEKAV
                     IKTDVAVSIPEGYVGLLTSRSGVSSKTYLVIETGKIDAGYHGNLGINIKNDMEHDGIT
                     SLYEDLDDKLVNTLDIKGNYINEGEGARKIYKINKGDKLAQLVIVPIWTPELKQVEEF
                     ESVSERGAKGFGSSGV"
     gene            751..957
                     /locus_tag="RFE25_002020"
     CDS             751..957
                     /locus_tag="RFE25_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1381 domain-containing protein"
                     /protein_id="HDU2817061.1"
                     /translation="MTQYLVTTFKDSTGQPHEHFTTARDNQTFTVVEAESKEEAKEKY
                     EAQVKRDAIIKLGQLFENIRECRK"
     gene            954..1148
                     /locus_tag="RFE25_002021"
     CDS             954..1148
                     /locus_tag="RFE25_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000132921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817062.1"
                     /translation="MTDVKIKTISGGVYFVKTAEPFEKYVERMTSFNGYIYASTIIKQ
                     PTYIKTDTIESITLIEERGK"
     gene            1145..1348
                     /locus_tag="RFE25_002022"
     CDS             1145..1348
                     /locus_tag="RFE25_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817063.1"
                     /translation="MNQLRILLHDGSSLILHEDELFNEIVFVLDDFRNDDDYLTIEKD
                     YGRELVLNKGYIVGINVEEADDD"
     gene            1341..1514
                     /locus_tag="RFE25_002023"
     CDS             1341..1514
                     /locus_tag="RFE25_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator RinB"
                     /protein_id="HDU2817064.1"
                     /translation="MTKQILRLLFLLAMYELGKYVTEQVYIMMTANDDVEAPSDFAKF
                     SDQSDLMRAEVSE"
     gene            1515..1661
                     /locus_tag="RFE25_002024"
     CDS             1515..1661
                     /locus_tag="RFE25_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817065.1"
                     /translation="MMWLIIAIILLVILLFGVMLQAEQLKGDLKVKEREIEILRSRLR
                     HFED"
     gene            1676..2095
                     /locus_tag="RFE25_002025"
     CDS             1676..2095
                     /locus_tag="RFE25_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDU2817066.1"
                     /translation="MSLRKSTQRYLESELSNYNYFDKDIARVRDEVLNPWSQQDTNIG
                     GDRVQSNVSVTEIKAIRVVNDRRLSQLARMKSAIEVVYNHSTVETQKLMELYYFKKPR
                     TLNLTGVAQEINVSKSTAYDMRKDILTRLADELGIIH"
     gene            2282..2776
                     /locus_tag="RFE25_002026"
     CDS             2282..2776
                     /locus_tag="RFE25_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDU2817067.1"
                     /translation="MNELTKKQRLFAEVYTIPGTECYGNATKSAVHAGYSEKTAYSQG
                     QRMLKNVEIQSYIKEVETKLFDENIMSGKEVLYRLTRTARGEHSEVEAVVTKTGDYKE
                     NPDTGKMQLVYDEHIQLVSKSPKISDQNKALEMLGRHHKLFTDKQEVDYKIPMFVDNI
                     PEDD"
     gene            2779..4074
                     /locus_tag="RFE25_002027"
     CDS             2779..4074
                     /locus_tag="RFE25_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HDU2817068.1"
                     /translation="MYEILDLKNKIGGGYNKFWHNKSFYRVVKGSRGSKKSKTTAINF
                     VYRLMKYDWANILVVRRFSNTNKQSTYTDLKWATNQLGVAHLFKFNESLPEITYKPTG
                     QKILFRGLDDPLKITSITVDTGILCWAWFEEAYQIETFAKFSTVVESIRGSYDSPEFF
                     KQITVTFNPWSERHWLKPTFFDEETKLNNTFSDTTTYRVNEWLDKVDIERYEDLYIKN
                     PRRARIVCDGDWGVAEGLVFDNFKVEDFDWFVEFKRTQEITHGMDFGFSQDPTTVVST
                     VVDLKNKKLFIYDEHYEKAMLTDDIKQMLIKKGLDDVDIAADYGAGGDRVISELKSKG
                     IKGIRKALKGANTILPGIQFIQGFEVIIHPSCEHAIEEFNTYTFDQDNDGKWLNKPID
                     ANNHIIDALRYSLEKYHIVRKKRKKNIESKTKVIKSLGL"
     gene            4085..5620
                     /locus_tag="RFE25_002028"
     CDS             4085..5620
                     /locus_tag="RFE25_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDU2817069.1"
                     /translation="MLKVNEFETDTDLRGNINYLFNDEANVVYTYDGTESDLLQNVNE
                     VSKYIEHHMDYQRPRLKVLSDYYEGKTKNLVELTRRKEEYMADNRVAHDYASYISDFI
                     NGYFLGNPIQYQDDDKDVLEAIEAFNDLNDVESHNRSLGLDLSIYGKAYELMIRNQDD
                     ETRLYKSDAMSTFVIYDNTIERNSIVGVRYLRTKPIDKTDEDEVFTVDLFTSHGVYRY
                     LTSRTNGLKLTPRENVFESHSFERMPITEFSNNERRKGDYEKVITLIDLYDNAESDTA
                     NYMSDLNDAMLLIKGNLNLDPVEVRKQKEANVLFLEPTVYADSEGRETEGSVDGGYIY
                     KQYDVQGTEAYKDRLNSDIHMFTNTPNMKDDNFSGTQSGEAMKYKLFGLEQRTKTKEG
                     LFTKGLRRRAKLLETILKNTRSIDANKDFNTVRYVYNRNLPKSLIEELKAYIDSGGKI
                     SQTTLMSLFSFFQDPELEVKKIEEDEKESIKKAQKGIYKDPRDINDDEQDDDTKDTVD
                     KKE"
     gene            5627..6622
                     /locus_tag="RFE25_002029"
     CDS             5627..6622
                     /locus_tag="RFE25_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDU2817070.1"
                     /translation="MPNKNTQEYWEERGRKAIENELKRDKTKAEEIERILNMMIKRIE
                     KEINAFIVKYGDFAGVTLQEAQKIIDEFDVKAFQEEAKRLVENKDFSDRANEELKKYN
                     TKMYVSREQMLKIQIEFLIAYATAQTELSMREYFESTAYRVFSDQAGILGEGVQVAKE
                     VIDTIVDTQFHGVVWSERLWTNTEAMKQEVEEIIANVVIRGRHPNEYVKDMRKHLNKF
                     EGTARQKTAAIKSLLYTESARVHAQSSIDSMKEISPEGYYMYIAKIDNRTTKVCKGLN
                     GEIFKVKDAKIGVNFYPMHINCRSDCALLPKSMWPKKPSKKRKTKYFGGKVKSGD"
     gene            6695..6865
                     /locus_tag="RFE25_002030"
     CDS             6695..6865
                     /locus_tag="RFE25_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817071.1"
                     /translation="MSNTDKYLRDIARELKGIRKELQKRNETVIIDANLDSVRSAVLA
                     DKEKSKYNEPLF"
     gene            7000..7614
                     /locus_tag="RFE25_002031"
     CDS             7000..7614
                     /locus_tag="RFE25_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HDU2817072.1"
                     /translation="MDIQEKLKLKLQFFAEESDGDNGKSKDNNDDEGKDKQDKKTNSE
                     EEIEKRLQEEYNKRLKEELSRRMKQKEKEKQEAVDEAKRLAKMNKDQIAEYEREQMEK
                     ELEQLRSEKQLNEMRSEARKMLSEAEVDSSDEVVNLVVTDTAEQTKLNVEAFSNAVKK
                     AVNEAVKINARQSPLTGGDSFNHSTKNKPKNLAEIARQKRIIKN"
     gene            7628..8602
                     /locus_tag="RFE25_002032"
     CDS             7628..8602
                     /locus_tag="RFE25_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDU2817073.1"
                     /translation="MEQTQKLKLNLQHFASNNVKPQVFNPDNVMMHEKKDGALMNEFT
                     TPILQEVMENSKIMQLGKYEPMEGTEKKFTFWADKPGAYWVGEGQKIETSKATWVNAT
                     MRAFKLGVILPVTKEFLNYTYSQFFEEMKPMIAEAFYKKFDEAGILNQGNNPFGKSIA
                     QSIEKTNKVIKGDFTQDNIIDLEALLEDDELEANAFISKTQNRSLLRKIVDPETKERI
                     YDRNSDTLDGLPVVNLKSSNLKRGELITGDFDKLIYGIPQLIEYKIDETAQLSTVKNE
                     DGTPVNLFEQDMVALRATMHVALHIADDKAFAKLVPADAKPSSNPGEV"
     gene            8624..8911
                     /locus_tag="RFE25_002033"
     CDS             8624..8911
                     /locus_tag="RFE25_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817074.1"
                     /translation="MPEIIGIVKVDFTDLEDNRHVYMKGHVYPRKGYDPTDERIKALA
                     SVENKRNEQMIYIVNDKLTKKELVEIASVAGLQVDEKQTKAEIINTFESLE"
     gene            8920..9252
                     /locus_tag="RFE25_002034"
     CDS             8920..9252
                     /locus_tag="RFE25_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HDU2817075.1"
                     /translation="MTTLADVKKRIGLKDEKQDEQLEEIIKSCESQLLSMLPIEVEQI
                     PERFSYMIKEVAVKRYNRIGAEGMTSEAVDGRSNAYELNDFKEYEAIIDNYFNARTRT
                     KKGRAVFF"
     gene            9249..9551
                     /locus_tag="RFE25_002035"
     CDS             9249..9551
                     /locus_tag="RFE25_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817076.1"
                     /translation="MRYEDRAVFQSEQAATYNPKTSKKENTLITYDAIPCNINPISRA
                     RKQLEFGDVKNDVSVLRIKESISYPVSHVLINGIRYKIIDTKTYRHETSYYIEEVN"
     gene            9551..9898
                     /locus_tag="RFE25_002036"
     CDS             9551..9898
                     /locus_tag="RFE25_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDU2817077.1"
                     /translation="MNIDGLDALLNQFHDMKNNIDDDVDDTLQEKAKEYVVRAKLKAR
                     EVMNKGYWTGNLSRNIRYKKTGDLQYTITSHAAYSGFLEFGTRYMEAEPFMWPVYEVI
                     RKSTVEELKALFE"
     gene            9910..10293
                     /locus_tag="RFE25_002037"
     CDS             9910..10293
                     /locus_tag="RFE25_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817078.1"
                     /translation="MTPNLQLYNKAYETLQGYGFPVISRKEMQQEIPYPFFVIKMPES
                     NRSKYTFDSYSGDTNLVIDIWSVSDDLGHHDGLVKRCIDDLTPSVKTNDYDFEEEDTN
                     ITQLVDDTTNQELLHTSVTISYKTF"
     gene            10312..10893
                     /locus_tag="RFE25_002038"
     CDS             10312..10893
                     /locus_tag="RFE25_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HDU2817079.1"
                     /translation="MANMKNSNDRIILFRKAGEKVDATKMLFLTEYGLSHEADTDTED
                     TMDGSYNTGGSVESTMSGTAKMFYGDDFADEIEDAVVDRVLYEAWEVESRIPGKNGDS
                     AKFKAKYFQGFHNKFELKAEANGIDEYEYEYGVNGRFQRGFATLPEAVTKKLKATGYR
                     FHDTTKADALTGEDLTAIPQPKVDSPPVAPREV"
     gene            10955..11320
                     /locus_tag="RFE25_002039"
     CDS             10955..11320
                     /locus_tag="RFE25_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HDU2817080.1"
                     /translation="MNVEINGKSLELSFGFKFLREIDNRLGLKVEQASIGQGVSMLPV
                     GLESGNPVVIGEVLIAATSHLKKQAITINNIDEALDEIAENIGLEEFGSDILTELGKR
                     PMTRNLVEVVETEEKPAEA"
     gene            11350..11694
                     /locus_tag="RFE25_002040"
     CDS             11350..11694
                     /locus_tag="RFE25_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817081.1"
                     /translation="MSTLGITDLNVIEQMTLTEYNYRMYAKEYEMLTQEFERYKLAFA
                     IRDAAATKNVGTENKPKEEYVFNNANDVLPYEENIQRLNEGKDIRFSSERDEYEPQNN
                     EFFKVIAEFNKQ"
     gene            11711..15175
                     /locus_tag="RFE25_002041"
     CDS             11711..15175
                     /locus_tag="RFE25_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817082.1"
                     /translation="MTEYKIKATIEASVAKFKKQIDSAVKSVQKFKRVADQTKDVELN
                     ANDKKLQKTIKVAKKSLDAFSNKNVKAKLDASIQDLQQKILESNFELDKLNSKEASPE
                     VKLQKQKLTKDIAEAEAKLSELEKKRVNIDVNADNSKFNRVLKVSKASLEALNRSKAK
                     AFIDVDNGVANSKIKRTKEELKSIPNKTRSRLDVDTGLSIPTIYAFKKSLDALPNKKT
                     TKVDVDTNGLKKAYAYIIKANDNFQRQMGNLANMFRVFGTVGSNMVGGLLTSSFSILI
                     PVIASVVPVVFALLNAIKVLTGGVLALGGAVAIAGAGFVAFGAMAISAIKMLNDGTLQ
                     ASSATNEYKKALDGVKSAWTDIIKQNQSAIFTTLANGLNTVKTAMQSLQPFFSGISRG
                     MEEASQSVLKWAENSSVASRFFNMMNTTGVSVFNKLLSAAGGFGDGLVNVFTQLAPLF
                     QWSADWLDRLGQSFSNWANSAAGENSITRFIEYTKTNLPIIGNIFKNVFVGINNLMNA
                     FGGSSTGIFQSLEQMTAKFREWSEQVGQSQGFKDFVSYIQTNGPLIMQLIGNIARGLV
                     AFATAMAPIASAVLRVAVAITGWIANLFEAHPATAQLVGVIITLVGAFRFLIAPILAV
                     MDFLGPLAARLVALVTKFGWAKTGTLVLSKAMTSLKGPIKLVTAIFQLLFGKIGLIRN
                     AITGLVTVFGILGGPITIVIGVIAALIAIFVLLWNKNEGFRNFIINAWNAIKTFMVTV
                     WNVLKTVASVVWNAILKAITTAVSNVYNFIMIIWNQIVAYLQGLWNGIIAIATTVWNL
                     LVTIITTVFTTIMTIVMTIWTAIWTFLSTIWNTIITIATTIWNLLVTVITTVFTTIMT
                     IAITIWNAIWTFLQTLWNTIVTVATKVWNAITTAISTALQAAWSFISNIWNTIWSFLS
                     GILTTIWNKVVSIFTQVVSTISDKMSQAWNFIVTKGMQWVSTITSTLINFVNRVVQGF
                     VNVVNKVSQGMTNAVNKIKSFIGDFVSAGADMIRGLIRGIGQMAGQLVDAAKNVAKKA
                     LDAAKSALGIHSPSREFMDVGMYSMLGFVKGIDNHSSKVIRNVSNVADKVVDAFQPTL
                     NAPDISSITGNLSNLGGNINAQVQHTHSIETSPNMKTVKIEFDVNNDALTSIVNGRNA
                     KRNSEYYL"
     gene            15188..16135
                     /locus_tag="RFE25_002042"
     CDS             15188..16135
                     /locus_tag="RFE25_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HDU2817083.1"
                     /translation="MDIELTKKDGTVIKLSEYGFIVNDIVIDSMQINTKYQDKENMNG
                     RILMGSNYISRDIVVPCFCKVKNRSDIAYMRDMLYSLTTDIEPMYLREIRRKEELNYR
                     FTQPTSDDYVKLDKNNFPDYEYSRHDQQIYVNGKQYKVIFNGVINPKQKGNKVSFELK
                     FETTELPYGESIGTSLELEENKKVGLWSFDFNIDWHAGGDKRKYTFENLSKGTVYYHG
                     SAPNDQFNMYKKITIILGEDTESFVWNLTHAEIMKIEGIKLKAGDRIVYDSFRVYKNG
                     VEISTETNIAQPKFKYGANKFEFNQTVQKVQFDLKFYYK"
     gene            16144..18045
                     /locus_tag="RFE25_002043"
     CDS             16144..18045
                     /locus_tag="RFE25_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDU2817084.1"
                     /translation="MTITIKPPKGNGAPVPVETTLVKKVNADGVLTFDILENKYTYEV
                     INAIGKRWIVSHVEGENDKKEYVITVIDRKSEGDRQLVECTAREIPIDKLMIDRIYVN
                     VTGSFTVERYFNIVFQGTGMLFEVEGKVKSSKFENGGEGDTRLEMFKKGLEHFGLEYK
                     ITYDKKKDRYKFVLTPFANQKASYFISDEVNANAIKLEEDASDFATFIRGYGNYSGEE
                     TFEHAGLVMEARSALAEIYGDIHAEPFKDGKVTDQETMDKELQSRLKKSLKQSLSLDF
                     LVLRESYPEADPQPGDIVQIKSTKLGLNDLVRIVQVKTIRGINNVIVKQDVTLGEFNR
                     EQRYMKKVNTAANYVSGLNDVNLSNPSKAAENLKSKVASIAKSTLDLMSRTDLIEDKQ
                     QKVSSKTVTTSDGTIVHDFIGKSNIKDVKTIGTIGDSVARGSHAKTNFTEMLGKKLKA
                     KTTNLARGGATMATVPIGKEAVENSIFRQAEQIRGDLIILQGTDDDWLHGYWAGVPIG
                     TDKTDTKTFYGAFCSAIEVIRKNNPASKILVMTATRQCPMSGTTIRRKDTDKNKLGLT
                     LEDYVNAQILACSELDVPVYDAYHTDYFKPYNPAFRKSSMPDGLHPNERGHEVIMYEL
                     IKNYYQFYG"
     gene            18060..19970
                     /locus_tag="RFE25_002044"
     CDS             18060..19970
                     /locus_tag="RFE25_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817085.1"
                     /translation="MDNKLITDLSRVFDYRYVDENEYNFKLISDMLTDFNFSLEYHRN
                     KEVFAHNGEQIKYEHLNVTSSVSDFLTYLNGRFSNMVLGHNGDGINEVKDARVDNTGY
                     DHKTLQDRLYHDYSTLDAFTKKVEKAVDENYKEYRATEYRFEPKEQEPEFITDLSPYT
                     NAVMQSFWVDPRTKIIYMTQARPGNHYMLSRLKPNGQFIDRLLVKNGGHGTHNAYRYI
                     GNELWIYSAVLDANENNKFVRFQYRTGEITYGNEMQDVMPNIFNDRYTSAIYNPIENL
                     MIFRREYKASERQLKNSLNFVEVRSADDIDKGIDKVLYQMDIPMEYTSDTQPMQGITY
                     DAGILYWYTGDSNTANPNYLQGFDIKTKELLFKRRIDIGGVNNNFKGDFQEAEGLDMY
                     YDLETGRKALLIGVTIGPGNNRHHSIYSIGQRGVNQFLKNIAPQVSMTDSGGRVKPLP
                     IQNPAYLSDITEVGHYYIYTQDTQNALDFPLPKAFRDAGWFFDVLPGHYNGALRQVLT
                     RNSTGRNMLKFERVIDIFNKKNNGSWNFNPQSAGYWEHIPKSITKLSDLKIVGLDFYI
                     TTEESKRFSDFPKDYKGIAGWVLEVKSNTPGNTTQVLRRNNFASAHQFFVRNFGTGGN
                     SGWSIIEGKEVE"
BASE COUNT         7482 a         2842 c         4067 g         5625 t
ORIGIN      
        1 acaggaaaat gagcattagt gtaggagaca aggtttttaa tccagaaaca aattcaactt
       61 tagaaattgt acaacttgtt ggcgatatta gagacacgca ttacaagtta tctgacggat
      121 ctattattag tcttatagac tttgttgtta aaccaattca tttaatcaag gaggcacagg
      181 aaaatgacta acacattaca agtgaaacta ttatcaaaag acgctagaat gcccgaacga
      241 aatcataaga cagatgcagg ttatgacata ttctcagccg aaaccgtcgt acttgagccg
      301 caagaaaagg cagtgattaa aacagatgta gctgtaagta taccagaggg ctatgtcggg
      361 ctattaacta gccgtagtgg tgtaagtagt aaaacgtatt tagtgattga aacaggaaag
      421 atagacgcgg gatatcatgg taatttaggg attaatatca agaatgatat ggagcatgac
      481 ggcataacat cattatacga agatttagac gacaaactag taaatacttt agatataaaa
      541 ggtaattata taaacgaagg agaaggcgct agaaagatat ataaaatcaa caaaggcgac
      601 aaactagctc aattggttat cgtgcctata tggacaccgg aactaaagca agtggaggaa
      661 ttcgagagtg tttcagaacg tggagcaaaa ggcttcggaa gtagcggagt gtaaagacat
      721 cttagatcga gtcaaggagg ttttggggaa gtgacacaat acttagtcac aacattcaaa
      781 gattcaacag gacaaccaca tgaacatttt actactgcta gagataatca gacgtttaca
      841 gttgttgagg cagagagtaa agaagaagcg aaagaaaagt acgaggcaca agttaaaaga
      901 gatgcaatta ttaaattagg tcagttgttt gaaaatataa gggagtgtcg gaaatgacgg
      961 atgttaaaat taaaactatt tcaggtggag tttattttgt aaaaacagct gaaccttttg
     1021 aaaaatatgt tgaaagaatg acgagtttta atggttatat ttacgcaagt actataatca
     1081 agcaaccaac gtatattaaa acagatacga ttgaatcaat cacacttatt gaggagcgtg
     1141 ggaaatgaat cagctgagaa ttttattaca tgacggtagt agtttgatat tacatgaaga
     1201 tgaattattt aacgaaatag tatttgtttt ggatgatttt agaaatgatg atgactattt
     1261 aacgatagaa aaagattatg gcagagaact tgtattgaac aaaggttata tagttgggat
     1321 taatgttgag gaggcagacg atgactaaac aaatattaag actattattc ttactagcga
     1381 tgtatgagct aggtaagtat gtaacggagc aagtatatat tatgatgacg gctaatgatg
     1441 atgtagaggc gccaagtgac ttcgcaaagt ttagtgatca gtctgatttg atgagggcgg
     1501 aggtgtcaga gtagatgatg tggttaatca tagcaattat attactagtc atcttattgt
     1561 ttggcgtgat gttacaagct gaacagttaa aaggcgattt gaaagttaaa gagcgagaga
     1621 tagaaatatt aagaagtaga ttgagacact ttgaagatta acgggggtta aacgaatgag
     1681 tttgagaaaa tcaacgcaaa gatatttaga aagtgaatta agcaattaca actacttcga
     1741 taaagatata gcgcgtgtaa gagatgaagt tttaaacccg tggagtcaac aagatactaa
     1801 tatcggtgga gatagggttc aaagtaatgt aagtgtaact gaaataaaag ctattagggt
     1861 tgttaacgat agaagattat cacaattagc tagaatgaag tcggctatag aggttgtgta
     1921 taatcacagt actgtagaga ctcaaaaact tatggagctt tattatttca aaaaacctag
     1981 aacattaaat cttactgggg ttgctcaaga aattaacgtg agtaagtcga ctgcttatga
     2041 tatgagaaaa gatatattaa ctcgattagc agatgaatta ggaataatac attaagtttg
     2101 gaaaaagtct ggaaaaataa cgtcactttc ggtgttaata tgatagcgta agatattgac
     2161 tatcttactg cgtttccctt atcgcaatta ggaataaagg atctatgtgg gttggctgat
     2221 tatagccaat ccctttttta attttaaaaa gcgtatagcg cgagagttgg tggtaaatga
     2281 aatgaacgaa ttaactaaaa agcaacgttt gtttgcagaa gtatatacaa tacccggtac
     2341 tgaatgttat ggcaacgcta ctaagtcagc tgtgcatgct ggatatagcg aaaagacggc
     2401 gtactcacaa ggacagcgta tgttgaagaa tgttgaaata caaagttata tcaaggaggt
     2461 tgaaacaaaa ctctttgatg agaatatcat gtcaggtaaa gaagtgttgt atagactaac
     2521 tagaacagct agaggagaac actcagaagt tgaagcagtc gtaacaaaaa ctggagacta
     2581 taaagagaat cccgacactg gcaaaatgca attggtatac gatgaacaca tacaacttgt
     2641 ttctaagtca cctaaaataa gtgaccaaaa caaagcttta gagatgttag gtagacacca
     2701 taaattattt acagacaaac aagaagttga ctacaaaata ccaatgtttg tcgataatat
     2761 tccggaagat gattagtcat gtatgaaata cttgatctaa aaaataaaat cggtggtggc
     2821 tacaataagt tttggcacaa taaaagtttt taccgtgtcg ttaaaggttc aaggggtagc
     2881 aagaaaagta aaactaccgc tattaatttt gtttatcgat taatgaaata tgattgggca
     2941 aatatacttg tagtcagacg atttagcaac actaacaaac aatcaacgta tacagattta
     3001 aagtgggcaa ccaaccaatt gggtgttgct cacttattta aattcaacga aagtttgccg
     3061 gaaataacgt ataaacctac tggacaaaaa atactgttta gaggtttaga tgacccattg
     3121 aaaataacat cgattactgt tgatactggc attttgtgtt gggcttggtt tgaagaggct
     3181 tatcaaatag aaacattcgc taagtttagc actgttgttg agtcaatacg tggtagctac
     3241 gatagtccgg aatttttcaa gcaaatcaca gtcactttta acccgtggtc ggaaagacat
     3301 tggttgaagc ctacattttt tgatgaagaa acaaaattaa acaatacttt ttcagataca
     3361 acaacttata gagttaatga atggctagat aaagtcgata ttgaacgata tgaagatttg
     3421 tatataaaga atcctagacg tgcaagaatc gtttgcgatg gagattgggg cgttgcagaa
     3481 gggcttgtat tcgataattt taaagtggaa gactttgatt ggtttgtgga gtttaaaaga
     3541 actcaagaaa taactcatgg aatggatttt ggatttagtc aagaccctac aacagttgtt
     3601 agtacggttg tcgatttaaa aaacaaaaag ttattcatct atgatgaaca ctatgaaaaa
     3661 gcgatgctaa ctgatgatat aaaacaaatg cttattaaaa aaggattaga tgatgtagat
     3721 attgcagccg attatggtgc tggcggagat agagtgatca gtgaattgaa atctaaaggg
     3781 attaaaggta taagaaaagc attgaaaggc gctaatacta ttttaccagg cattcaattc
     3841 attcaaggct ttgaagttat tatacaccca tcatgtgaac acgctattga agagttcaac
     3901 acttatacat ttgaccaaga taatgatggt aagtggttga acaagcctat agatgctaat
     3961 aaccatatta tcgatgcatt gcgttatagt cttgagaaat atcatatcgt acgtaaaaaa
     4021 cgtaaaaaga atatagaaag caaaacaaaa gtaattaaat ctctaggatt ataggaggga
     4081 acaaatgtta aaagtaaacg aatttgaaac agatacagat ctacggggaa acataaatta
     4141 cttatttaat gatgaagcca atgttgttta cacatatgac gggacggaat ccgatttatt
     4201 acaaaacgtt aatgaagtaa gtaaatacat tgaacatcac atggattacc aacgacctag
     4261 attaaaagtg ttgagtgatt actacgaagg taaaactaag aatctggttg agttaacacg
     4321 acgcaaagaa gagtacatgg cagataaccg tgtagcgcat gattacgcat cttatattag
     4381 tgattttatt aacggttatt tcttaggtaa tccaattcaa tatcaagatg atgacaaaga
     4441 tgtattagaa gctattgagg cgttcaatga tttgaatgat gttgagtcgc acaatagatc
     4501 tttaggatta gatttgtcaa tttatggtaa agcttatgaa ttaatgatta gaaaccaaga
     4561 tgatgaaacg cgtttataca agagtgatgc aatgagtact tttgtcatat acgacaatac
     4621 aattgaacgt aatagtatcg taggcgttag atatttaaga actaaaccaa tagacaagac
     4681 tgacgaagat gaagtgttta cagttgattt atttacttct cacggtgttt atagatatct
     4741 taccagtaga acaaatggat tgaagctcac accacgtgaa aacgtttttg aatcacactc
     4801 tttcgaacgt atgcctatta cagaatttag caacaacgaa agaagaaaag gggattatga
     4861 gaaagtaatc actttaattg atttgtatga taatgctgaa tcagatactg ctaactatat
     4921 gagtgattta aatgacgcta tgttacttat taaaggtaat ttaaatttag atcctgtaga
     4981 agttagaaaa caaaaggaag ctaacgtgtt gtttttagaa ccgactgttt atgctgatag
     5041 cgaaggtaga gaaacagaag gttcagttga cggtggttat atttataagc aatacgatgt
     5101 acaaggtacc gaagcttata aagaccgttt gaacagtgat atacacatgt ttaccaacac
     5161 gcctaacatg aaagatgata actttagtgg cactcaatcg ggcgaggcaa tgaaatacaa
     5221 attatttgga ttggaacaac gtactaaaac taaagaagga ttgtttacta aagggttaag
     5281 acgtcgtgct aagttattag agacgatact taaaaacaca cggtcaattg acgctaacaa
     5341 agatttcaat acagttaggt acgtatacaa cagaaactta cctaaatcat tgattgaaga
     5401 attaaaagct tatattgatt ctggcgggaa gattagtcaa acaactttga tgtctctatt
     5461 ctcgttcttc caagaccctg aattggaagt caagaaaata gaagaagatg agaaagaatc
     5521 tattaaaaaa gctcaaaaag gtatttataa agaccctaga gacatcaatg atgacgaaca
     5581 agatgatgat acaaaagata ctgttgataa aaaggaatga ttgtaattgc ctaacaaaaa
     5641 cactcaagaa tattgggaag aacgcggacg caaagcaatc gagaatgagt tgaagcgtga
     5701 taaaactaaa gctgaagaaa tagaacgtat attgaatatg atgattaagc gcattgaaaa
     5761 agagatcaat gcgtttattg ttaagtacgg agattttgca ggcgttacat tacaagaagc
     5821 acaaaagatt attgatgagt tcgatgtaaa agcgtttcaa gaagaagcaa aaagattggt
     5881 cgaaaacaag gactttagcg atagagcaaa tgaagaatta aagaagtata acactaagat
     5941 gtatgtatct agagaacaga tgttaaagat tcaaatagaa ttcttaattg cttatgcaac
     6001 agctcaaaca gaattatcga tgagggaata tttcgaatca acagcttatc gtgtgttcag
     6061 tgatcaagcg ggtattttag gtgaaggtgt acaagtagct aaagaagtta tagatacaat
     6121 cgttgataca caatttcatg gtgtcgtttg gtcagagcga ttatggacta atactgaagc
     6181 gatgaaacaa gaagtagaag aaataattgc taatgtagtt attagaggtc gacatcctaa
     6241 tgaatatgtt aaagatatgc gcaagcactt aaataaattc gaaggcacag cacgacaaaa
     6301 gaccgcagca attaaatcat tgctttatac ggaatcggca cgtgttcacg cacaatcaag
     6361 cattgacagc atgaaagaaa tttcaccgga aggatattat atgtatattg caaaaatcga
     6421 taatagaaca actaaagtat gcaaagggct taatggagaa atattcaaag ttaaagacgc
     6481 taaaattggt gttaatttct atcctatgca tatcaattgt cgttcagatt gcgctttact
     6541 acctaaatct atgtggccga aaaaaccaag caagaaacga aaaacaaaat acttcggagg
     6601 gaaagtgaaa agcggtgatt gatttaaaag taaagttttt taaaggcaag ttagttttgt
     6661 atgacagtaa attaaatgtt tggaggatac taatatgagt aatactgaca aataccttag
     6721 agacatagca agagaattaa aaggtatacg taaagagtta caaaagcgaa acgaaacagt
     6781 tattattgat gcaaacttag acagtgtaag gtcggcagta ttagccgata aagaaaaatc
     6841 gaaatataat gaacctctct tttaatagct agcacttaat tgtgttggct attttttatg
     6901 tccaaaccat gcttatgaca ataaaagatg caagtgtaac agcccgaacc atgtatggct
     6961 taaaactaat caagagtaaa taaatgaggt gtaaaaacta tggatatcca agaaaagtta
     7021 aaactcaagt tacagttttt tgctgaagaa tcagatggag ataatggaaa atcaaaagat
     7081 aacaacgatg atgaaggcaa agacaaacaa gacaaaaaga ctaattcaga agaagaaatc
     7141 gaaaaaagac tacaagaaga atataacaag cgtcttaaag aagaattaag tcgtcgtatg
     7201 aagcagaaag aaaaagagaa acaagaagct gttgatgaag ctaaacgatt agcaaaaatg
     7261 aacaaagatc aaatcgctga atatgaacgc gaacaaatgg aaaaagagct ggagcaatta
     7321 cgctcagaaa aacaattaaa tgaaatgcgt tcagaagcaa ggaaaatgtt aagtgaagca
     7381 gaagttgatt catcagatga ggttgttaat ttagttgtaa cagatactgc tgaacaaact
     7441 aaattgaatg ttgaagcttt ttctaatgca gtaaaaaaag cggttaatga agcggttaag
     7501 attaacgcta gacaatcgcc attgactggt ggagattcat ttaatcactc gactaaaaat
     7561 aaaccgaaaa acttagctga aatagctaga caaaaaagaa ttattaaaaa ttaacggagg
     7621 catttaaatg gaacaaacac aaaaattaaa attaaatttg caacattttg cgagtaacaa
     7681 tgttaaaccg caagtattta accctgataa tgtaatgatg cacgaaaaga aagatggcgc
     7741 gttgatgaat gaattcacaa cgcccatctt acaagaggtt atggaaaact ctaaaattat
     7801 gcaattaggt aagtacgaac caatggaagg tactgagaag aagtttactt tttgggctga
     7861 taaaccaggt gcttactggg taggtgaagg tcaaaaaatc gaaacatcta aagctacatg
     7921 ggttaatgct actatgagag cgtttaaatt aggggttatc ttacctgtaa caaaagagtt
     7981 tttgaattac acttattcac aattctttga agaaatgaag cctatgattg ctgaagcatt
     8041 ctataaaaag tttgatgaag cgggtatttt gaatcaaggt aacaatccat tcggtaaatc
     8101 aattgcacaa tcaattgaaa aaactaataa ggttattaaa ggtgacttca cacaagataa
     8161 cattattgat ttagaggcat tacttgaaga tgacgaatta gaagcaaatg cgtttatctc
     8221 aaaaacacaa aacagaagct tgttacgtaa aattgtagat cctgaaacga aagaacgtat
     8281 ttatgaccgt aacagtgata cgttagatgg tctacctgtg gttaacctta aatcaagcaa
     8341 cttaaaacgt ggtgagttaa tcactggtga tttcgataag ttgatttacg gtatccctca
     8401 attaattgaa tacaaaatcg atgaaactgc acaattatct acagtcaaaa atgaagatgg
     8461 aacacctgta aacttgtttg aacaagacat ggtggcatta cgtgcaacta tgcatgtagc
     8521 attgcatatc gctgatgata aagcgtttgc taagttagtt cctgctgatg caaaaccatc
     8581 ttcaaatcca ggagaagttt aataaataat taggagtggt aacatgcccg aaatcattgg
     8641 aattgttaaa gtagatttta cagatttaga agataacaga catgtctata tgaaagggca
     8701 tgtctaccct cgcaaaggtt atgatcctac agatgaacgt atcaaagctt tagctagtgt
     8761 tgaaaataaa cgcaacgaac aaatgattta cattgtaaat gacaaattaa ccaaaaaaga
     8821 acttgtcgaa atagcaagtg ttgctggctt acaagttgat gaaaaacaaa caaaagctga
     8881 aattatcaac acttttgagt cgctagagta ggtggttata tgactacgct agctgatgta
     8941 aaaaaacgta ttggccttaa agatgaaaag caagatgaac aattagagga aattataaaa
     9001 agttgtgaaa gccagttgtt atcaatgtta cctattgaag ttgaacaaat accggaaagg
     9061 tttagttaca tgattaaaga agttgcagtt aaacgctaca acaggattgg tgctgaaggt
     9121 atgacatcag aagcggttga cggacgtagc aatgcgtatg aattgaacga tttcaaggag
     9181 tatgaagcta ttattgataa ttactttaat gctagaacga gaactaaaaa aggaagggct
     9241 gtgttctttt gagatatgaa gatagagccg tctttcaatc agaacaagca gcaacttaca
     9301 atcctaaaac tagcaaaaaa gaaaacactc taatcactta tgatgcgata ccatgcaata
     9361 ttaatcctat ttctagagca agaaagcaac ttgaattcgg cgatgtaaaa aacgatgtaa
     9421 gtgtcctgag gataaaagaa tcaatatctt accctgttag ccacgtgtta attaatggta
     9481 ttcgctacaa gataattgat acaaagacat acagacacga aacgtcatat tatatcgaag
     9541 aggtcaattg atgaatatag acggattaga cgcactgtta aaccaatttc acgatatgaa
     9601 aaacaacatc gatgatgatg tagatgatac tttacaagaa aaagccaaag aatatgtagt
     9661 acgagctaaa ttgaaagcta gagaagtaat gaataagggt tattggactg gtaatttatc
     9721 acgcaatatc agatataaaa aaactggcga tttgcaatac actatcacat cgcatgcagc
     9781 ttatagtggt ttcttagagt ttggtactcg atacatggag gcagaacctt ttatgtggcc
     9841 agtatatgag gtaataagaa aatcaactgt agaagaattg aaagcgttgt ttgaatagga
     9901 gataaaagca tgacaccgaa cttacaactt tataataaag cgtatgaaac gctacaagga
     9961 tatggattcc ctgttatttc tcgtaaagag atgcaacaag agattccgta tccttttttt
    10021 gtaataaaaa tgccggagtc aaacagaagt aaatacacgt ttgatagtta ttctggtgac
    10081 acgaatttag ttattgatat ttggagtgta agtgatgatt taggacatca tgacggactt
    10141 gttaaaagat gtattgatga tttaacacct agcgttaaaa caaacgatta tgactttgaa
    10201 gaagaagata ctaacatcac acagttagtt gatgatacta ccaatcaaga attgctacac
    10261 acatcagtaa cgatatctta caaaacattt taaaaaacgg aggaatattg aatggcaaat
    10321 atgaaaaata gtaatgatcg tattatttta tttagaaaag ctggcgaaaa agtagatgct
    10381 actaaaatgc tttttttaac tgaatacggc ttatcacatg aagctgatac agatacagag
    10441 gatacaatgg acggttctta taacactggt ggttctgttg agtcaacaat gtctggtact
    10501 gctaaaatgt tttatggtga cgattttgca gatgaaattg aagatgcagt tgtagatcgc
    10561 gtattgtatg aagcttggga agttgaaagt agaataccag gcaaaaatgg ggattccgct
    10621 aaatttaaag cgaaatattt ccaaggtttc cacaataaat ttgaattaaa agcagaagct
    10681 aacggtattg atgaatatga atatgaatat ggagtgaatg gtcgtttcca acgtggattt
    10741 gcaacactac ctgaggctgt aacaaagaaa cttaaggcga ctggatacag attccacgac
    10801 actacaaaag cagatgcatt aactggcgaa gatttaacag caattccaca acctaaagta
    10861 gattcaccac cggttgcacc aagagaggta taaaaatagg gcgttaagcc ctttttattt
    10921 tgtttaaatt aattatgaat ggagatttta agttatgaat gtagaaatta acggaaagtc
    10981 attagaatta agttttggtt ttaaattttt aagagaaatc gataaccgat taggtttaaa
    11041 agttgaacaa gcttctatcg gtcaaggtgt atcaatgttg cctgtaggtt tagaaagtgg
    11101 aaatccggtt gtgattggcg aagttttaat cgcagctaca tctcacttaa aaaaacaagc
    11161 aattactatt aataacattg atgaagcatt agatgaaatc gcagaaaata tcggactaga
    11221 agaattcggt tcggatattt taacggagtt gggaaagcga cctatgaccc gaaacctagt
    11281 cgaagtagtg gaaacggaag aaaaaccagc ggaagcctaa taacttacga cagaatcgtt
    11341 ataacttgta tgtcaacact tggtattaca gatttgaacg ttattgagca aatgacatta
    11401 acagaatata actatcgaat gtatgcgaaa gagtatgaaa tgctaaccca agaattcgaa
    11461 cgttacaaac ttgcgtttgc tattcgtgat gctgcagcta ctaaaaatgt tgggacagaa
    11521 aataaaccta aagaggaata tgtttttaac aatgcaaacg acgtattgcc ttatgaagaa
    11581 aatatccaac ggcttaacga aggtaaagat ataagattta gtagcgaacg tgatgaatac
    11641 gaaccacaaa ataatgaatt ctttaaagtt atagcagaat ttaataagca atagaaagag
    11701 aggtgttaat gtgacggaat ataaaattaa agcgactatt gaagctagtg tagctaaatt
    11761 caaaaagcaa attgatagtg cggttaaatc tgtacaaaaa ttcaaaagag tagcagatca
    11821 aactaaagat gttgaattaa acgctaacga taaaaaatta caaaaaacta tcaaggttgc
    11881 taaaaagtct ttagatgcct ttagcaacaa aaatgtaaaa gctaaattag atgctagtat
    11941 acaagactta caacaaaaga tattagaatc aaattttgaa ctagacaaac ttaactccaa
    12001 agaagctagc ccagaagtta aactacaaaa acaaaagtta actaaagata tcgctgaagc
    12061 agaagctaag ttatccgaac tggaaaagaa acgtgtcaat attgacgtca atgcagataa
    12121 cagtaaattc aatcgagtgt taaaagtatc taaagctagt cttgaagcat taaataggtc
    12181 taaagctaaa gcttttatag acgtggacaa tggtgttgct aactctaaaa tcaaacgcac
    12241 taaagaagag cttaaaagta ttccaaacaa aactagatct cgactagatg tagatacagg
    12301 gctttctata ccaactattt atgcgtttaa aaaatcatta gacgcattgc cgaacaaaaa
    12361 aacaacaaag gtagatgtcg atactaatgg tttaaagaaa gcttatgcct acataataaa
    12421 agcaaatgac aattttcaaa gacagatggg gaatttagct aatatgttcc gtgtgttcgg
    12481 tactgtaggt tctaatatgg ttggtggatt acttacatca tcttttagta tcttaatacc
    12541 tgtaatagcg agcgtagtac ctgtagtatt tgcgctatta aacgctatca aagtgttaac
    12601 tggtggtgta cttgctttag gtggtgccgt agcaatagcg ggagcaggat ttgtagcgtt
    12661 tggcgcaatg gctatcagcg ctataaagat gcttaatgat ggcactttac aagctagctc
    12721 agcaacaaac gaatacaaaa aagcgttaga tggcgtaaag tcagcatgga ctgatattat
    12781 aaagcaaaat caatccgcta tcttcacaac tcttgcaaat ggtttaaata ctgttaaaac
    12841 tgcaatgcag agcttacaac cgttttttag tggtatttca agaggaatgg aagaagcgtc
    12901 tcaaagcgtg cttaaatggg ctgaaaatag cagtgtagct tcaagattct ttaatatgat
    12961 gaatacaacg ggtgtttcgg tatttaacaa gctattaagt gctgcaggtg gttttggtga
    13021 cggattagtc aatgtattca cgcaattagc accactgttt caatggtcgg ctgattggtt
    13081 ggatagatta ggtcaatctt tctctaactg ggctaatagt gcagctggag aaaattcgat
    13141 aactcgtttt attgaataca caaaaacaaa cttacctatc attggtaata ttttcaaaaa
    13201 tgttttcgtt ggaattaata atttgatgaa tgcattcggt ggatcatcaa ctggcatatt
    13261 ccaatctctt gaacaaatga cagctaagtt tagggaatgg tctgaacaag taggacaatc
    13321 tcaaggtttt aaagactttg tcagttatat acaaacaaat ggaccactaa taatgcaatt
    13381 gattggaaac atcgcaagag gattagttgc attcgcaaca gcgatggctc ctatagctag
    13441 tgcagtatta cgcgttgcag tagcaataac tggttggata gctaacttgt ttgaggcgca
    13501 tccggctaca gcacaattag ttggtgtcat tataacttta gttggtgcat ttagattttt
    13561 aattgctcca atattagcgg taatggattt tctggggcca ttagcagcaa gattagtcgc
    13621 attagtaact aagtttggtt gggctaaaac aggaacttta gtattaagta aggcaatgac
    13681 atcattaaaa ggtccaataa aattagttac agctatattc caattgttat tcggtaagat
    13741 tggattaatt agaaatgcta tcacaggact tgtaactgtg tttggtattt taggtggtcc
    13801 aataacgata gttattggtg taatcgctgc attaatagct atatttgttt tattgtggaa
    13861 taaaaatgaa ggattcagaa actttattat aaatgcttgg aatgcgataa aaacatttat
    13921 ggttacagtt tggaatgtgt tgaaaactgt agcttcggtt gtatggaatg ctattttaaa
    13981 agctatcact acagcggtat caaatgtata caattttata atgattattt ggaatcaaat
    14041 agttgcttat ttgcaagggc tatggaatgg aattatcgct attgcaacaa cagtatggaa
    14101 ccttttagtt acaatcatta caactgtttt cacgacgata atgacaatag ttatgacgat
    14161 atggacagct atttggacat tcttaagtac aatctggaac acgataatta caatcgctac
    14221 tacgatttgg aatttgttag tcactgtaat aactacagtg tttaccacaa ttatgactat
    14281 cgcaataaca atttggaacg ctatttggac gttcttacaa acgttgtgga acactatagt
    14341 tactgtggca actaaggttt ggaacgctat cactacagct atatctactg cgttacaagc
    14401 ggcatggagt tttatttcta atatatggaa tacgatttgg agtttcttat ctggtatatt
    14461 aacgacaatt tggaataaag ttgtaagcat attcacacaa gttgtttcaa ctatatcaga
    14521 caaaatgtct caagcttgga acttcattgt cactaaaggt atgcaatggg tatctactat
    14581 aacaagtacg ctaattaact ttgttaatag agttgttcaa ggattcgtta atgttgtaaa
    14641 caaagttagt caaggtatga caaatgcagt aaataaaata aaaagcttta taggagattt
    14701 tgtgtctgca ggtgctgata tgatccgtgg tttaattaga ggtattggac aaatggctgg
    14761 tcaattagta gatgcagcta aaaatgttgc taagaaagct ttagatgcag ctaaaagtgc
    14821 tttgggtatt cactcacctt cacgtgaatt catggatgtt ggtatgtatt caatgctagg
    14881 tttcgttaaa ggtatagata atcattcaag taaagttatc cgtaatgttt ctaatgttgc
    14941 agataaagta gttgatgcat ttcaacctac attaaacgca cctgacattt ctagtattac
    15001 aggaaactta agtaatttag gtggaaatat aaatgcgcaa gtacaacaca cacattctat
    15061 tgaaacatca ccgaacatga aaactgttaa aattgaattc gatgtcaata acgatgcgct
    15121 tactagtatt gttaacggca gaaatgctaa acgcaattct gagtattact tataaaggag
    15181 gttacaaatg gacatagaat taacaaaaaa agatggtact gtaatcaaat taagtgaata
    15241 cgggtttatc gttaacgata tagtaattga tagcatgcaa atcaacacaa agtatcaaga
    15301 caaagaaaat atgaacggtc gtatattaat ggggagcaat tatatcagta gagatatagt
    15361 tgttccttgt ttttgtaaag ttaaaaatcg ttcagacatt gcttatatgc gagatatgtt
    15421 gtattcgtta acgacagaca tagaacctat gtatttgcga gaaatcagaa gaaaagaaga
    15481 gttgaattac aggtttactc aaccaacttc tgatgattac gtgaaattag ataaaaacaa
    15541 cttcccggat tacgaatatt caagacacga tcaacaaatt tatgtaaatg gtaaacagta
    15601 taaagttatt tttaacggag ttataaaccc taaacaaaaa ggtaataaag tttcttttga
    15661 actaaaattc gaaactacag aattaccata cggtgaaagt attggaacaa gcctagagtt
    15721 agaagaaaac aaaaaggttg gattgtggtc gtttgatttt aatattgatt ggcatgcagg
    15781 cggagacaaa agaaagtata catttgaaaa tttgagcaaa ggtacagttt attatcacgg
    15841 tagtgctcct aacgaccaat tcaacatgta taaaaagata acaattattt taggcgaaga
    15901 tacagaatcg tttgtatgga atttaacgca tgctgaaata atgaaaatcg aagggatcaa
    15961 actaaaagct ggagacagaa ttgtttatga tagcttccga gtttataaaa acggtgttga
    16021 aataagtacc gaaacgaata tagcccaacc aaaatttaaa tacggagcta ataaatttga
    16081 gtttaatcaa acggtacaaa aagttcagtt tgatttgaaa ttttattata agtaggtgtc
    16141 agaatgacaa taactattaa accacctaaa ggtaatggcg cacctgtacc agtagaaaca
    16201 actttagtaa aaaaagttaa tgctgacggt gtattaactt ttgatattct agaaaataaa
    16261 tatacttatg aagttattaa cgctataggg aaaagatgga ttgttagtca tgtcgaaggt
    16321 gaaaacgaca agaaagaata tgtaataact gtcattgata ggaaatcaga aggtgacaga
    16381 caactggttg aatgtactgc tagagagatt cctatagaca agttaatgat tgataggatt
    16441 tatgttaatg taacaggatc ttttacagta gaaagatatt ttaacattgt gtttcaaggt
    16501 actggaatgc tttttgaagt cgaaggtaag gttaagtctt cgaagtttga aaatggtggt
    16561 gaaggcgaca caaggttaga aatgtttaaa aagggattag aacatttcgg tttagaatat
    16621 aaaataacgt atgacaaaaa gaaagacaga tataagtttg tattgacgcc ttttgcaaat
    16681 caaaaagcgt cttattttat ttctgacgaa gtcaacgcca acgctataaa actcgaggaa
    16741 gatgcaagtg atttcgccac cttcattaga ggatatggta attattcagg agaagaaaca
    16801 ttcgaacacg ctgggctcgt aatggaagct agaagtgcat tagctgaaat atacggcgac
    16861 atccacgcag aaccatttaa agatggtaaa gtgactgacc aagaaactat ggataaagaa
    16921 ttacaatcga gattgaaaaa gtcgttaaaa caatctttgt ctttggactt tttggtgtta
    16981 agagaatcat atccagaagc agacccacaa cccggagaca tagtacaaat aaaatctacc
    17041 aaactaggtt tgaatgattt agtccgtata gtacaagtta aaacgattag gggtataaac
    17101 aatgtaattg ttaagcaaga tgtaacgctt ggtgagttta atcgagaaca acgatatatg
    17161 aaaaaagtta atactgcagc taactatgtt tctggattaa atgatgttaa cctttctaat
    17221 cctagtaaag cggcagaaaa cttgaagtct aaagtagcgt caatagctaa atcaacactc
    17281 gatttgatga gtagaactga tttgattgaa gataaacaac agaaggtaag ctctaaaact
    17341 gtgactacat ctgacggcac tatcgttcat gattttatag gtaaatcaaa cattaaagat
    17401 gtaaaaacaa ttggaacgat tggcgattct gtagctagag gatcacatgc gaaaactaat
    17461 ttcacagaaa tgttaggcaa gaaattgaaa gccaaaacga ccaaccttgc aagaggtggc
    17521 gctacaatgg caacagttcc aataggtaaa gaagcggtag aaaacagcat ttttagacaa
    17581 gcagagcaaa taagaggaga cctaatcata ttacaaggta cagatgatga ctggttacat
    17641 ggttattggg caggtgtacc gataggcact gataaaacgg atacaaaaac gttttacggt
    17701 gccttttgtt ctgcaattga agttatccgg aaaaataatc cggcttcaaa aatacttgtt
    17761 atgacagcta ctagacaatg tcctatgagt ggcacaacga tacgtcgtaa agatacggat
    17821 aaaaacaaac tagggttaac gttagaggat tatgtcaatg ctcagatatt ggcttgtagt
    17881 gaattggatg taccagtata tgatgcctat catacagatt attttaagcc atataatcca
    17941 gcgttcagaa aatcaagtat gccagacgga ttgcatccga acgagagggg tcatgaagtt
    18001 attatgtacg aacttattaa aaattattac cagttttacg gatagaaaag gaggaagaca
    18061 tggataacaa attaattaca gacttaagta gagttttcga ttacagatat gtagatgaaa
    18121 atgagtataa tttcaagctt atttcagaca tgctgactga ttttaatttc tctcttgaat
    18181 accatagaaa taaagaggta tttgcacata atggagagca aataaagtat gagcatttaa
    18241 atgtcacaag tagcgtctct gattttttaa cgtatctaaa cggccgtttc agcaatatgg
    18301 tactaggtca taacggcgac ggtatcaacg aagtaaaaga cgcgcgtgtt gataatactg
    18361 gttatgatca taagacattg caagatcgtt tgtatcatga ttattcaaca ctagatgctt
    18421 tcactaaaaa ggttgagaaa gctgtagatg aaaactataa agaatatcga gctacagaat
    18481 accgattcga accaaaagag caagaaccgg aattcatcac agatttatcg ccatatacta
    18541 acgcagtaat gcaatcattt tgggtagacc ctagaacaaa aattatttat atgacacaag
    18601 cgcgtccggg caatcattac atgttatcta gattgaagcc taatggacaa tttattgata
    18661 gattgcttgt taaaaatggc ggtcacggca cacacaacgc ctatagatat atcggcaatg
    18721 agttatggat ttattcagca gtgttagacg ctaacgaaaa caacaagttt gtacgtttcc
    18781 aatatagaac tggagaaata acttatggta atgaaatgca agatgtcatg ccgaatatat
    18841 ttaacgacag atatacatca gcgatttata atcctataga aaatttaatg attttcagac
    18901 gtgaatataa agcttctgaa agacaactta agaattcgtt gaactttgtt gaggttagaa
    18961 gtgctgacga tattgataaa ggtatagaca aagtattgta tcaaatggat atacctatgg
    19021 aatacacttc agatacacaa cctatgcaag gtatcactta tgatgcaggt atcttatatt
    19081 ggtatacagg tgattcgaat acagccaacc ctaactactt acaaggtttc gatataaaaa
    19141 caaaagaatt gttatttaaa cgacgtatcg atattggcgg tgtgaataat aactttaaag
    19201 gagacttcca agaagctgag ggtctagata tgtattacga tctagaaaca ggacgtaaag
    19261 cacttttaat aggggtaact attggacctg gtaacaacag acatcactca atttattcta
    19321 tcggccaaag aggtgttaac caattcttga aaaacatcgc gcctcaagta tcaatgactg
    19381 attcaggcgg acgtgttaaa ccgttaccaa tacagaaccc agcatatcta agtgatatta
    19441 cggaagttgg tcattactat atctatacgc aagacacaca aaatgcgtta gatttcccgt
    19501 taccgaaagc gtttagagat gcaggttggt tctttgatgt gctgcctgga cactataatg
    19561 gtgctctaag acaagtactt accagaaaca gcacaggtag aaatatgctt aaattcgaac
    19621 gtgttatcga catctttaac aagaaaaaca acggttcatg gaattttaac ccacaaagtg
    19681 ctggttattg ggaacatatc cctaagagca tcacgaaatt gtctgattta aaaattgttg
    19741 gtttagactt ctatatcacc actgaagaat caaaacgttt ttctgacttc cctaaagatt
    19801 acaaaggtat tgcaggctgg gtgttagaag taaaatcaaa tacaccgggt aacacaacac
    19861 aagtgctaag acgtaataac tttgcttctg ctcaccagtt tttcgttaga aactttggta
    19921 ctggtggtaa tagtggttgg agcataatag aaggtaagga ggttgaataa tggtagtaga
    19981 taatttttca aaagatgata acttaatcga gttaca
//
LOCUS       DAPDIM010000053        19013 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000053 DAPDIM010000000
VERSION     DAPDIM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 19013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19013
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.053"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            3..1655
                     /gene="ezrA"
                     /locus_tag="RFE25_002045"
     CDS             3..1655
                     /gene="ezrA"
                     /locus_tag="RFE25_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HDU2817086.1"
                     /translation="MAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNL
                     KGETKTKYDAMKKDNVESTNKYLAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDS
                     YEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANRHQFGEAASLLETEI
                     EKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQF
                     QDLKYGCRDLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDK
                     LDDMYDLIEHEVKAKNDVEETKDIITDNLFKAKDMNYTLQTEIEYVRENYYINESDAQ
                     SVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQEKLQNHL
                     IQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQF
                     SERPIHVKQLKDKVSKIVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKS
                     LNEAERLFKNNRYKRAIEIAEQALESVEPGVTKHIEEEVIKQ"
     gene            complement(1729..1870)
                     /locus_tag="RFE25_002046"
                     /pseudo
     CDS             complement(1729..1870)
                     /locus_tag="RFE25_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2019..3167
                     /locus_tag="RFE25_002047"
     CDS             2019..3167
                     /locus_tag="RFE25_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDU2817087.1"
                     /translation="MFILIYLDNAATTKAFEEVLDTYLKVNQSMYYNPNSPHKAGLQA
                     NQLLQQAKAQINAMINSKTNYDVVFTSGATESNNLALKGIAYRKFDTAKEIITSVLEH
                     PSVLEVVRYLEAHEGFKVKYVDVKKDGSINLEHFKELVSDKVGLVTCMYVNNVTGQIQ
                     PIPQMAKVIKNYPKAHFHVDAVQAFGKISMDLNNIDSISLSGHKFNGLKGQGVLLVNH
                     IQNVEPTVHGGGQEYGVRSGTVNLPNDIAMVKAMKIANENFEALNAFVTELNNDVRQF
                     LNKYHGVYINSSTSGSPFVLNISFPGVKGEVLVNAFSKYDIMISTTSACSSKRNKLNE
                     VLAAMGLSDKSIEGSIRLSFGATTTKEDIARFKEIFIIIYEEIKELLK"
     gene            3167..4390
                     /gene="thiI"
                     /locus_tag="RFE25_002048"
     CDS             3167..4390
                     /gene="thiI"
                     /locus_tag="RFE25_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDU2817088.1"
                     /translation="MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVK
                     GKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTIEAMSAAAIKFAQQFEE
                     NSTFKIDVKRADKNFPMDTYELQRELGGTVLKQIENVSVNVKRPDHEIRVEVRLDAIY
                     MYEEVVPGSGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQ
                     AKEKVIELTRILAERVGPIKLHIVPFTELQKQVNKVVHPRYTMTSTRRMMMRVADKLV
                     HQIGALAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTF
                     ETSIQPFEDCCTIFTPKNPVTEPNFEKVVQYESVFDFEEMINRAVENIETLEITSDYK
                     TIKEQQTNQLINDFL"
     gene            4434..5204
                     /locus_tag="RFE25_002049"
     CDS             4434..5204
                     /locus_tag="RFE25_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDU2817089.1"
                     /translation="MDLNLTMIIIIILFGFIAAFIDSVVGGGGLISTPALLAIGLPPS
                     VALGTNKLASSFGSLTSMIKFIRSGKVDLFVVAKLFGFVFLASACGAYIATMVPSQIL
                     KPLIIIALSSVFIFTLLKKDWGNTRTFTQFTFKKAIIFAALFILIGFYDGFVGGGTGS
                     FMLFVLLVFGFDFLSAAGNAKVLNFASNIGALVLFMVLGQVDYVIGLIMAISMIAGSY
                     TGAHFAIKQGVGYVKVLFIIITAILILKNAFDYIQQFV"
     gene            5302..5796
                     /gene="tpx"
                     /locus_tag="RFE25_002050"
     CDS             5302..5796
                     /gene="tpx"
                     /locus_tag="RFE25_002050"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HDU2817090.1"
                     /translation="MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAG
                     KKKLISVVPSIDTGVCDQQTRKFNSEASKEEGIVLTISADLPFAQKRWCASAGLDNVI
                     TLSDHRDLSFGENYGVVMEELRLLARAVFVLDVDNKVVYKEIVSEGTDFPDFDAALAA
                     YKNI"
     gene            5919..6866
                     /locus_tag="RFE25_002051"
     CDS             5919..6866
                     /locus_tag="RFE25_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDU2817091.1"
                     /translation="MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTN
                     ERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEE
                     LHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQD
                     AIMPLPLEEADIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINALKDAG
                     YAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSG
                     ETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK"
     gene            6954..8156
                     /locus_tag="RFE25_002052"
     CDS             6954..8156
                     /locus_tag="RFE25_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDU2817092.1"
                     /translation="MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFT
                     IEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESV
                     AITDEVEKEIEELSELTPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYL
                     YSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAID
                     GGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGL
                     SGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGEN
                     SVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARD
                     VMTFGGLK"
     gene            complement(8402..8902)
                     /locus_tag="RFE25_002053"
     CDS             complement(8402..8902)
                     /locus_tag="RFE25_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDU2817093.1"
                     /translation="MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSR
                     TYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAH
                     EINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQL
                     REKYQN"
     gene            9043..10161
                     /gene="ald"
                     /locus_tag="RFE25_002054"
     CDS             9043..10161
                     /gene="ald"
                     /locus_tag="RFE25_002054"
                     /EC_number="1.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HDU2817094.1"
                     /translation="MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSF
                     FEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKL
                     TQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLG
                     GVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIM
                     SNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFET
                     TDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFK
                     SNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL"
     gene            10285..10383
                     /locus_tag="RFE25_002055"
     CDS             10285..10383
                     /locus_tag="RFE25_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817095.1"
                     /translation="MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLG"
     gene            complement(10477..11532)
                     /locus_tag="RFE25_002056"
     CDS             complement(10477..11532)
                     /locus_tag="RFE25_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDU2817096.1"
                     /translation="MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFAL
                     LIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTV
                     ARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEG
                     VTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGV
                     IYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIIS
                     EKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIED
                     DILVTNEGYEVLTHYEK"
     gene            11707..12396
                     /locus_tag="RFE25_002057"
     CDS             11707..12396
                     /locus_tag="RFE25_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDU2817097.1"
                     /translation="MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYI
                     VLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGS
                     VKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPV
                     DVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDV
                     QILKPGESVQF"
     gene            complement(12701..13114)
                     /locus_tag="RFE25_002058"
     CDS             complement(12701..13114)
                     /locus_tag="RFE25_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDU2817098.1"
                     /translation="MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQ
                     ASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEI
                     VVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK"
     gene            13319..14617
                     /locus_tag="RFE25_002059"
     CDS             13319..14617
                     /locus_tag="RFE25_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDU2817099.1"
                     /translation="MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDAD
                     KMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGA
                     MELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPV
                     LSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANR
                     TGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMI
                     WEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGIT
                     VEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHI
                     TVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV"
     gene            14929..15870
                     /gene="pde2"
                     /locus_tag="RFE25_002060"
     CDS             14929..15870
                     /gene="pde2"
                     /locus_tag="RFE25_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pApA hydrolase Pde2"
                     /protein_id="HDU2817100.1"
                     /translation="MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQK
                     FPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGSKLI
                     KIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTG
                     RFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFC
                     QVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIIN
                     DIAQDFGGGGHPNASGVSVNSWDEFEQLATALRTKLN"
     gene            15891..>19013
                     /locus_tag="RFE25_002061"
     CDS             15891..>19013
                     /locus_tag="RFE25_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDU2817101.1"
                     /translation="MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLY
                     GFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNSM
                     ENVSFELLQQFSSNLIIIFKNVADEHRDIVQVFDSHEDTYLDHQSVLVQGIKHVWIQN
                     VCYQTRQDADTISALAAIRDNAKLDLIHDQEDFGAHFLTEKEIKQLDINQEYLTQVDV
                     IAQKCNAELKYHQSLLPQYQTPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYK
                     VITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLF
                     ERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVG
                     RIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLP
                     RHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSII
                     HQILIQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEH
                     FEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKNTYGVIIYQEQIMQ
                     IASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILK
                     FADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQG
                     ITILPPNINESHWFYKPSQEGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFAR
                     RIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPK
                     QMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNYKPILVQ
                     FDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHR
                     KQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVVLSFY
                     DETIKQMTTLG"
BASE COUNT         6683 a         2669 c         3534 g         6127 t
ORIGIN      
        1 tgattgctgt aggtgtatta ttctatttac gttcaaataa acgacaaatt attgaaaaag
       61 caatcgaacg taaaaatgaa attgagacgt taccttttga tcaaaacctt gcacaattat
      121 ctaagttgaa tttaaaaggt gaaacaaaaa cgaaatacga tgcaatgaaa aaggacaacg
      181 tagaaagtac aaataagtat ctagctcctg tggaagaaaa aatccataat gctgaggctt
      241 tattagataa atttagtttc aacgcatctc aaagtgaaat tgatgatgca aatgagttga
      301 tggatagtta cgaacaaagc tatcagcaac aattagaaga tgtaaatgaa attattgcgt
      361 tatacaaaga taatgatgaa ttatatgaca aatgtaaggt tgattatcgt gaaatgaaac
      421 gtgatgtttt agcaaatcgt catcaatttg gtgaggcagc aagtctactt gaaactgaaa
      481 ttgaaaagtt tgagccaagg ttagagcaat atgaagtact aaaagctgat ggtaattatg
      541 tacaagcgca caaccatata gctgccttga atgaacaaat gaaacagcta agatcttata
      601 tggaagaaat accagaatta attagagaaa ctcaaaaaga attacctggt caattccaag
      661 atttaaaata tggttgccgt gatcttaaag ttgaagggta tgatctggat cacgtaaaag
      721 tagacagtac attacaaagc ttaaaaacag agcttagttt cgttgaacca ttaattagcc
      781 gcttagaatt agaagaagct aatgataaac tagctaatat caatgataag ttagatgaca
      841 tgtatgattt aattgaacat gaagttaaag ctaaaaatga tgtcgaagaa acaaaagata
      901 tcattacgga taacttattc aaagctaaag acatgaatta tacattgcaa acagaaattg
      961 aatatgtacg tgaaaactac tatataaatg aatctgatgc tcaaagtgtt cgtcaatttg
     1021 aaaatgaaat tcaaagttta atttctgtat atgatgatat tttaaaagaa atgtctaaat
     1081 ctgctgtacg atatagcgag gttcaggata atttacaata tttagaagat catgtcacag
     1141 ttattaatga caaacaagaa aagctacaaa atcatctgat tcaattgcgt gaagatgaag
     1201 cagaagcaga agacaatctg ctacgagtac aatcgaagaa agaagaagtg tatcgtcgat
     1261 tacttgcttc taacttaaca agcgttcctg aaaggtttat catcatgaaa aatgaaattg
     1321 atcatgaagt tcgtgatgtt aacgaacaat ttagtgaacg tccaatacac gttaaacagt
     1381 taaaagataa agtgtctaaa attgtgattc aaatgaatac atttgaagat gaagcaaatg
     1441 atgttcttgt taatgctgtt tatgcagaga aattaattca atatggaaat agatatcgta
     1501 aggactatag caatgttgat aagagcttaa atgaagctga acgattattt aaaaataatc
     1561 gctataagcg tgcgattgaa attgcagagc aagctcttga aagtgttgag ccaggtgtca
     1621 ctaaacatat tgaagaagaa gttattaagc aatagaaact agtatgtagt tatacttaaa
     1681 taatatgagc actctgtcaa attggactga tgagtttaat aattgaagtt agccaacgat
     1741 acgttgtcta gcttcttttt ttatatggat aaatgaaagg gacaataaat ataaatagca
     1801 attgtttaaa gataaacgta atcaaatgtg ttgttttaat taatataagt agtgaaaaaa
     1861 gcataatcac acagctgttt aaatagagtg aaatagtcta attcttattt aataagtaga
     1921 aataagatta ttttgcgcta taacctttat tttttgtcgg ataatagtat aatgcttgag
     1981 taaaacaatt ttaacgattg atgattaatg aaagagaagt gtttattttg atatatctag
     2041 ataatgcggc aacgacgaaa gcatttgaag aagtgttaga tacttattta aaagtaaatc
     2101 aatcaatgta ttataatccg aatagtccgc ataaagctgg tttgcaggca aatcaattac
     2161 tacaacaagc aaaagcccaa attaatgcaa tgattaattc aaaaacaaat tatgatgttg
     2221 tattcactag tggtgcaact gaatccaata atcttgcttt aaaaggtatt gcctatcgta
     2281 aatttgatac agcgaaggaa ataattacat ccgtgttaga gcatccgtcc gtattagagg
     2341 ttgtaagata tttggaagca cacgaaggat ttaaagttaa atatgttgat gtaaagaaag
     2401 atggcagtat taacttagaa cacttcaaag aattagtgtc agacaaagtc ggtttagtaa
     2461 catgtatgta tgtaaataat gtaactggac aaatacagcc tattccacaa atggctaaag
     2521 ttataaaaaa ttatcctaag gcacattttc atgtagatgc ggttcaagca ttcggcaaaa
     2581 tttcaatgga tctcaataac atagatagta ttagtttaag tggacacaag tttaatggtt
     2641 taaaaggaca aggcgtctta cttgtaaatc acattcaaaa tgttgaacca actgtccatg
     2701 gtggtggtca agaatatggc gttagaagtg gaacagttaa tttgccaaat gatattgcaa
     2761 tggttaaagc gatgaagata gctaatgaaa actttgaagc attgaatgca tttgttactg
     2821 agttaaataa tgacgtccgt caatttttaa ataaatatca tggagtttat attaattctt
     2881 caacttcagg ttcaccattc gttttaaata ttagttttcc tggcgtaaaa ggtgaagtat
     2941 tagttaatgc tttttcaaaa tatgacatta tgatatctac gacgagtgct tgttcatcta
     3001 aacgtaataa attaaatgaa gtattggctg caatgggatt atcagacaaa tctattgaag
     3061 gtagtataag attatcattt ggggctacta caactaaaga agatatagca aggtttaaag
     3121 aaatatttat catcatttat gaggaaatta aggagttgct aaaataatga agtatgatca
     3181 cttgcttgtt agatacgggg agttaacatt aaagggttca aatagaaaaa aatttgtaaa
     3241 tcaattaaga aataatgtaa ataagtcatt aaaaggactt gatgggtttg tcgttaaagg
     3301 caaacgagat cgtatgtata ttgaacttga agaccatgca gatataaatg aaataacata
     3361 tcgattatca aaaattttcg gtattaaatc tattagtcca gtattaaaag tagaaaaaac
     3421 aatagaggca atgagtgcag cggcaattaa atttgcgcag caatttgaag aaaacagcac
     3481 atttaaaatt gatgtgaagc gtgccgataa aaatttccca atggatacgt atgaattaca
     3541 acgtgaattg ggtggtaccg tattgaaaca aattgaaaat gtttctgtta atgtcaaacg
     3601 tccagatcat gaaattcgag tggaagttag attagatgca atttatatgt atgaagaagt
     3661 tgttccgggt tcaggcggat taccagttgg tactggtggt aagacgttac taatgctttc
     3721 aggcggtata gactcaccag ttgctggaat ggaagtgatg agacgtggcg taacaattga
     3781 agcgattcat ttccatagtc caccatttac aagtgatcaa gcaaaagaaa aagttattga
     3841 attgacacgt attttagctg aacgtgttgg accaattaaa ttgcatattg taccatttac
     3901 agaattgcaa aaacaggtaa ataaagttgt acatccaaga tatacaatga cttcaacgag
     3961 acgtatgatg atgcgtgttg ctgataaatt agtacatcaa ataggggctt tagctattgt
     4021 aaatggtgaa aacctagggc aggtagccag tcaaacactt catagcatgt atgcaattaa
     4081 taatgtaact tctactcctg tattacgtcc tttattaact tacgataaag aagaaattat
     4141 tattaaatcg aaagaaattg gtacatttga aacatctatt caaccatttg aagattgttg
     4201 tacaattttc acccctaaaa atccagtaac cgaaccaaac tttgaaaagg tagtccaata
     4261 tgaaagtgtc tttgattttg aagagatgat taatcgtgct gttgaaaata ttgaaacact
     4321 tgaaataact agtgattata aaactattaa agaacagcaa acaaaccaat taataaatga
     4381 ctttttataa ataaaatcct agagtaaatt taaacataag gggatgttaa actatggatt
     4441 tgaacttaac gatgattata atcataattt tatttggttt tatcgcggcg tttatagatt
     4501 cggttgtagg gggtggcggt ttaatttcta cgccagcatt attagcaatc ggtctaccac
     4561 catctgtggc tttaggtaca aataaattgg caagttcatt tggttcttta actagtatga
     4621 taaagtttat aaggtccggt aaagtggact tatttgttgt tgccaaatta tttggttttg
     4681 tatttttggc atctgcatgt ggcgcatata ttgcaacgat ggttccgtca caaatattga
     4741 aacctctaat cattattgca ctttcgtcgg tgtttatatt cacattactt aaaaaagatt
     4801 ggggcaatac acgcacgttt actcaattta catttaagaa agccataata tttgcagcac
     4861 tttttatatt aatcggcttt tatgatggat ttgtaggtgg gggaacaggt tcatttatgc
     4921 tttttgtatt gttagtcttt ggttttgatt ttttaagtgc agcaggaaat gctaaagttt
     4981 tgaactttgc ttctaatata ggtgcgcttg tattatttat ggtattagga caagtagatt
     5041 atgtaatagg tttaattatg gctataagta tgattgctgg gtcatatact ggagcacatt
     5101 ttgctatcaa acaaggtgtt ggctatgtaa aagtattatt tattattatt actgctattt
     5161 taattttaaa aaatgctttt gattatattc aacaatttgt ataaaattaa atttgctttt
     5221 gattaaagca tgaaaattgt aatcaaacca taaattgtcg tatgatgtag ttagaatttt
     5281 aaaatgcagg aggtcaagta tatgactgaa ataacattca aaggtggacc aatccactta
     5341 aaaggtcaac aaattaatga aggtgatttt gcacctgatt ttacagtgtt agataatgac
     5401 ttaaatcaag taacattagc agattatgct ggtaaaaaga aattaattag tgtggtacca
     5461 tcaattgata caggtgtttg tgatcagcag actcgcaaat tcaactctga agcttctaaa
     5521 gaagagggga ttgtgcttac aatttcagca gacttaccat tcgcacaaaa aagatggtgc
     5581 gcttcagcag gtttagacaa tgtcattaca ttaagtgacc accgtgactt atcatttggt
     5641 gaaaactatg gcgttgttat ggaagaactt cgcttattag ctcgtgcagt atttgtatta
     5701 gatgtagata ataaagttgt ttataaagaa atcgttagtg aaggtactga tttcccagat
     5761 tttgatgctg ctttagctgc atacaaaaat atttaatcat taaagagata aatcttaaaa
     5821 tgtatacatc gtgtccatcg ttgtcaacag cattaaaata gaattgtttt ctatgattgc
     5881 taagacctat gggcactttt tattggagag ggacgaatat ggcagaacaa caaacaatta
     5941 tggaacgctt gtttcataca ttagatgaaa aagctaaaac attaaataat gaaaatggcc
     6001 aaagttttat tgaaaatctt gggctagcaa tggaacaagt atataccaat gaaagaggat
     6061 tgttagaaca atcgacgtta caagatcgac gtaaagcatt ccaatttgca tatttaagtt
     6121 taatgcagga agaaaagata caagcaaatc atcaaattac accagattca attggattga
     6181 tactaggatt tttagttgag cgttttatga acaaccaaga agaattacat attgttgata
     6241 ttgcaagtgg tgccggtcat ttaagtgcta ctgtaaaaga agtgttacct gaaattgcgg
     6301 ttatgcatca tttaattgaa gttgatccag ttttatcacg tgttagtgta catttagcaa
     6361 acttcttaga aattcctttc gatgtgtatc ctcaagatgc catcatgcca ctaccattag
     6421 aagaagcaga tatcgttatt ggtgattttc cagtaggcta ttatccaatt gatgaaagaa
     6481 gtaaggagtt taagctaggt tttgaagaag gacatagtta ttcacattat ttattaatag
     6541 aacaagcaat aaatgcatta aaagatgctg gatatgcctt tctagtggta ccaagtaata
     6601 tttttacagg tgaacatgta aaacagcttg aaaaatatat tgcaacagag acagagatgc
     6661 aagcattttt aaatttacca ccaactttat ttaaaaatga aaaagcgcga aaatctatat
     6721 taattttaca aaagaaaaaa tcgggtgaaa caaagccagt tgaagtatta ttggcaaata
     6781 ttcctgattt caaaaatcct tcacaatttc aaggatttat gacagagtta aatcagtgga
     6841 tggacacaaa tcgtcctaaa aaataatctg taatagtata gtcataaaac tgtatgaatg
     6901 ataaaatgag aaatgaaata gtataaaaag caaacgatgg aggatcatta cttatgtcaa
     6961 aattaatctt ggctatcaat gctggtagtt catcattaaa atttcaatta attagaatgc
     7021 ctgaagagga attagtaaca aaaggtttaa tagaaagaat cggattgaag gattcaattt
     7081 ttacaattga agtcaacggg gaaaaagtta aaacagtaca agatatcaag gatcacgttg
     7141 aggcagttga tatcatgttg gatgctttta aagcgcataa tattattaat gatattaacg
     7201 atatcgatgg aacaggtcac cgtgttgtac atggtggtga aaaattccct gaatcagtag
     7261 ctattactga tgaggttgaa aaggaaattg aagaattaag cgaattaaca ccgcttcaca
     7321 acccagctaa cttgatgggt attcgtgctt tccgtaagtt attaccaaat atccctcatg
     7381 tggcaatttt tgatacagca ttccatcaaa caatgcctga aaaagcatat ctatatagct
     7441 tgccatatca ttattataaa gattatggca ttcgtaagta tggtttccat ggtacaagcc
     7501 ataaatttgt atcacaaaga gcggcagaaa tgttagataa gccaattgaa gatttacgta
     7561 ttatttcatg tcacattggt aatggagcat caattgcagc tatcgatggc ggtaaatcta
     7621 ttgatacatc aatgggcttc acaccacttg ctggtgtaac aatgggtact cgttctggta
     7681 atattgaccc tgctttaatt ccatttatta tggaaaaaac aggtaaaact gctgaacaag
     7741 tattggaaat cttaaacaaa gaatcaggtt tattaggatt atcaggtaca tctagtgatt
     7801 tacgtgactt atcagaagaa gctgaatcag gtaaagcacg ttcacaaatg gctttagatg
     7861 tatttgcttc taaaattcac aaatatattg gatcatatgc tgcgagaatg catggtgttg
     7921 atgttatcgt atttacagca ggtatcggtg aaaactcagt agaaattcgt gcgaaagttc
     7981 ttgaaggctt agaatttatg ggtgtttact gggatcctaa gaaaaatgaa aacttactac
     8041 gtggtaaaga aggatttatt aactatcctc attcaccagt taaagttgtc gttattccaa
     8101 cagatgaaga aagtatgatt gcccgtgatg ttatgacatt cggtggttta aaataatttt
     8161 taaataaata ttaagcgtct atctccgcta caattatatg taggaggtag acgctttttg
     8221 tattgtttga aaattaacta gtgtaatgtc tcttttcacg aatatcttaa agaattaagt
     8281 agtcgaagaa gattatgaaa acattattaa gtgagtttta tttataaaca ataaaaaacc
     8341 aagtgcagaa agttgcactt ggttcataat gatcaagtag ttatctaatg atcatctata
     8401 tttaattttg atatttttca cgtaattgag ttgttgcaac ttgtggttgg aagtctgctg
     8461 gtaactcttc agtacgaaca actaacacgt cacatggcgc atgacgaacg atagattctg
     8521 atacagaacc aacaataaat ctttccacgg catttaagcc tgatgtacca ctcataatca
     8581 agtctgcatt aatttcatgt gcaagctttt taggaatgat agatttagga gagccaaact
     8641 ctagacgcgt ttctacatct ttaacaccag cgttagtagc tacttcttta taaccattta
     8701 ataattcttc tgcaaaatgc ttagattttt cagtaaattg agcatcataa acttcataag
     8761 aagaatacgt tcttgaatca attacattca caattgttaa cttcgcatcg ttacgtttag
     8821 caacaccaac tgctctgtta aatgcccatt ccgcttcatg tgaaccgtca actgcgatta
     8881 aaatattttt gtaagtaatc atagtaagtg cctccttgtt ctttcttaat tatattttac
     8941 cacaattttc ggaaaagtca gtgtaataac ctttacaatt ttgtggattt ttgattgcgc
     9001 tttcaaaatg ttcgcgttaa gatgattatg gaggtggatg gtatgaaaat tggtatacca
     9061 agggagatta aaaataatga aaatcgtgtt ggtttatcac cgagtggtgt gcacgcttta
     9121 gtagaaagtg ggcatactgt tttagtggaa acaaatgcgg gttcaggatc gttctttgaa
     9181 gatgtagatt acaaagaagc aggtgctgag attgttgctg aacaagcaaa agtttgggat
     9241 gtggatatgg ttattaaagt taaagaacca cttgaatctg aatatccata ttttaaagaa
     9301 gggcttgtat tattcactta tcttcattta gcaaatgaag aaaaattaac acaagctttg
     9361 atagatagaa aagtaattag tattgcatat gagactgtgc agttaccaga ccgatcttta
     9421 ccattgttat caccaatgag tgaggtagca ggaagaatgt cagctcaagt tggcgcagag
     9481 ttcctacaaa aacttaatgg tggtatggga attctactag gtggtgtccc aggagtacct
     9541 aagggtaaag taactattat cggtggtggt caagcaggaa caaatgcagc taaaattgca
     9601 ctaggactag gtgcagatgt tacgatttta gatgttaatc caaagcgttt acaacaatta
     9661 gatgatttat tcggtggacg tgtacataca attatgtcaa atccgttgaa tattgagttg
     9721 tatgttaaac aaagtgattt agtaataggt gcagttttaa ttccaggtgc taaagcgcca
     9781 agacttgtaa cagaagacat gattaaacaa atgaaaaatg ggtcagttat tattgacatt
     9841 gctattgatc aaggcggtat ttttgaaaca actgataaaa ttacgacaca tgatgatcct
     9901 acatatatta agcatggtgt ggttcattat gcagttgcaa atatgccagg tgcagtaccg
     9961 cgtacttcga cgttagcttt aaataatgct acgctacctt atgcgctcat gctagctaat
    10021 aaagggtata gagaagcatt taaatcaaat caaccattat cattaggttt aaatacttac
    10081 aaaggtcacg taaccaataa aggcgttgca gaggcatttg aaatggaata taaatctgta
    10141 gaagaagcat tacaattata atttgaattt gatgaaaagg gaatggatta cagcgtacta
    10201 aagaatgacg ttatcatctc cttggttatt aaaattaaat aatgataaat taaagctaga
    10261 aacaatgcga agaaatcatc gaacatgaat gatattgatt tgattcatta catgttactg
    10321 atgaacatac ctgcatatgt gtttctagct tgtttgttac atattgcatt tagacttgga
    10381 taaaaattta tgtcttaggc gctacaatgt tatattggca gtgtttgact gaatgagaat
    10441 gtgcttgtaa caagcttttc atttttatcc cactccttat ttttcgtaat gtgttaatac
    10501 ttcatatcct tcattagtga caagtatgtc atcttcaatt cttacacctg caacacctgg
    10561 tacataaata cctggttcga ttgtaataac catgccagct tctaacaaat tagaattagt
    10621 acttgaaaca tcttgatatt catgttcttg taatcctaaa ccatgaccta agcgatgagg
    10681 gaaatattca ccataacctt tttctgaaat aatatttcta gcgatatgat cgatatcttt
    10741 taaaggtatt ccaggtttaa ttgcttggat tgcagatgtt tctgcttcta atacaatatt
    10801 ataaatttct tgtgcttctt tgctaggttc accaaattta atggtacgtg tcatatcgct
    10861 acaataatgc tcataaatta cacctaaatc aaatagtaca tattcattgc tttttaatct
    10921 gcgatctcct ggtgtgccat gaggtgatgc ggcatgatct ccaaataaaa ccatcgtatc
    10981 aaaactcatt tcattgacgc catattgttt gatagtttgc tcaatatggt tgactacttc
    11041 acgttcagtc acaccttctt ttaaataaga aacacctatt tcgatacact tatctgctaa
    11101 ctcagcagct ttacgtattt tgctaatttc atcttcggat ttaatatttc ttaattgttt
    11161 gattgttaaa tcaacatctc cgaatgaatt gacattgaaa ccagagatta attgtttttg
    11221 gcgtgctact gttaagtgct cgctttcaat tagtaattta ttgattgttt gaggataaag
    11281 tgaaaaagga ttttcagtgt ctaaatatcc aacgatttca cctgtgaaag gtgatgcttt
    11341 gacttcttcg acttccattt ttggacaaaa tagtacttgt ttaccatctt tcttaatcaa
    11401 taatgcaaat aatctttcat ggggttcgct acggtatcca gtaaaataat atacattcaa
    11461 cggtgttgta atccatgctg catcagcttg ttgattgttc agttcgtcta ttatttttga
    11521 tatttttgtc atttcataaa cactcctcaa cataatatta cttccatttt atgccaatta
    11581 ttattagatt tcaaaatcga gctaatacat taactagatt ttcaattttt aaaatttgag
    11641 aatttgttat aattaagtgg caaaagggta ctaaatttat atagcaattg ataggaggat
    11701 gctcaaatga agttatcatt tcatggtcaa tcaacgattt atttagaagg gaacaacaaa
    11761 aaggttatcg tagatccgtt tatttcaaat aaccctaagt gtgatttgaa tattgaaaca
    11821 gtgcaggtag actatatcgt tttaacgcac ggtcattttg atcattttgg tgatgttgtg
    11881 gaactagcaa agaaaacagg agcaacagta attggaagtg cagaaatggc tgactatctt
    11941 tcttcatatc acggtgttga aaatgttcat ggtatgaata ttggtggtaa agcaaacttt
    12001 gatttcggaa gcgttaaatt tgttcaagca tttcatagtt caagttttac acatgaaaat
    12061 ggtattccag tttatttagg tatgccaatg ggtatcgtgt ttgaagttga aggaaaaaca
    12121 atttatcata ctggtgatac aggtctgttt agtgacatgt cacttattgc gaaacgtcat
    12181 ccagttgatg tatgttttgt accaattgga gataatttta cgatgggtat tgatgatgca
    12241 agttatgcta ttaatgaatt tattaaacca aaaatttctg taccgattca ttatgataca
    12301 ttcccattaa tcgaacaaga tccacaacaa tttaaagatg ctgttaatgt aggggacgtg
    12361 caaattttaa aaccaggtga atctgttcag ttttaaatag aatatagatt ttacactaaa
    12421 aaacacctcg ctaatctatg tggaagttat cgtctgcata tttttagtgg gtgtttttat
    12481 attctactga ttcagttacg acgtggacgg gggacatcag tggttcttta tcatttctga
    12541 cctactctcg taattttagt tttatacaat tagacattga ttataaattt actacgatat
    12601 aaaaaatcca gaaccacagt cataatcatt tcttgtgttt actcagtcgt ttgagactgc
    12661 atcatgattg aaagattatt tgtgattctg gataaaaatt ttatttaacg attaatacag
    12721 ggatagtcgc acgttttgct actttgtggc tgacacttcc aagtacaaat ttctttttgt
    12781 cttctgcttt acggttactt aaaacaacaa tttcgtattt accgctatta gcatgtttta
    12841 atagttcttc ttttgcatta ccacgaacaa ttatttggtc ataatcaata ccataatctt
    12901 ctaaagcttt gcgtgttttt tccaatcgct tgcttcgttc ttcagtaagt ttgtttaaat
    12961 gaacacctgc tttaattgat gcttgagcat cttgttcgct gattgcgttt aaaactgtta
    13021 cgactgtacc ttcgccagct aatttagaca cttcttttag tgctttttca ttttttaact
    13081 gagtgtctac accaagtaat atatttttat acattagtac atccctcctc acttacattc
    13141 taataaataa taatggattt ttccatttaa aattaaagat tttgtgatct ttgtgtttgt
    13201 tgtatatttt caaaaaataa aataggtgaa acgatcatta tttcatttca cttcaatgct
    13261 ttttatccaa aataaagtta taatgtagtt aatactgttc gaaaagaaga ggtaaagaat
    13321 gacaaaacat gaacaaattt tagattatat tgaatcgtta tctataggct ctaaaatttc
    13381 ggtgcgtaaa atcgctaaat ttttaaacgt atctgaaggg acagcatatc gtgcaattaa
    13441 agatgctgat aaaatgggca tggtcgcaac gatagatcgt gttggtacgg ttcgaatcga
    13501 aaaacgtaat cgtaatgaaa ttgaacattt aacttttaat gaaattgtca atattattga
    13561 tggccaagtg ttaggtggca ataaaggtat cactaagatg gtatctaaat ttgcaattgg
    13621 agcaatggaa ctcaaagata ttttaaaata tattggtcca aagacattat tgattgtcgg
    13681 aaatcgcgaa gatgtgcaga ttgaagcttt aaaaagaggt acggctatat taattactgg
    13741 tggatttaag ccatctaata aagttattaa ttttgcgaat gaacatgatt tacctgttct
    13801 atcatcaagt tatgatacat tcctagttgc aaatattatc aacaaagcac tttttaatca
    13861 gaaaatacga aaagatatct taatagttca agatataatg acgccattag atgatttgtc
    13921 tgtgctgttt gatacgatga aaatagcaga ttataagcgt atggcgaatc gaactggcca
    13981 tacaagattt ccggtagtca atgagtcgta taaattagta ggtattgtaa caagtcgaga
    14041 gatgattaat acaaaggacg acgacgaaat agataaagtg atgacgcgaa accctattta
    14101 tgtaaatgct atgagtacag tagcaagttg tgcgcatatg atgatttggg aaggtattga
    14161 attgattcct gtcgtttcga gtaataaaaa gacagtgggt gtgattaata gacaagatgt
    14221 tttaaagtct atgcaacttt taggaagaca gcctcagatg ggtgaaacaa ttaacgatca
    14281 aatcgccaaa tatataacaa tgaatcaaga tggaattaca gtagaagttt caccactttt
    14341 aatcaatcat tacggaacag taagtaaagc ggcatttgta agtattatag aagaaacaat
    14401 acaatatgaa atgcgtaaat ttaaaaaagg taatgtcatg atagagaact taaatatcgt
    14461 gtatattaaa acagtaccta ttgaatcaca tataacagtg cgctttggca tactagacgt
    14521 cggaagaaac ttcgccaaaa tagaagtgaa catgcatagt caaaacgaca aagtagcgag
    14581 cgctctcgtg atatgccaaa tgtttgacga agtataggaa cttagcagag aaaataggca
    14641 taagatagat ttcgcacaaa cgttggagcc caacttacat tgtttgtaga atttcttttc
    14701 gaaattcttt gtgttggggc cccaccccaa cttgcatcgt ctgtagaaat tgggggtcca
    14761 atttcactgt gttggggccc ctgaactaaa tagtatggaa atatatatat ctaaataatt
    14821 aaaacgggca aatagtttaa tatggcagta acaattttta taatttagat attttgatat
    14881 agactaatgc ttaaattaag caacttttct aaaaaaggga gtatgaaaat gattagtact
    14941 ttgaatgaaa ttatgaaatg tatcgaagac aacgatacaa ttattataca cagacatgtt
    15001 agaccagatc cagatgcata tggttcacaa cttggtttaa aatactatat tcagcagaaa
    15061 tttccgcaaa agcaagtatt tgcagtgggt gaagcggaat catcattaag ttttattgga
    15121 gagttggata acattgatga taaaacatat caagatgcgc ttgtaattgt atgtgatact
    15181 gccaatgctc cacgaattga cgatgaacga tatagtacag gtagtaaact tattaaaata
    15241 gatcatcatc ctgcagttga tcagtatggt gatattaatt tagttaatac gaacgcgtca
    15301 tctacaagtg aaatcattta tgatttaatc tcacatttta atgatgaagc aattgttaat
    15361 aaagatatcg cgagtgtttt ataccttggt atcgtcggtg atactgggcg attccttttt
    15421 aacaatacct cagaacatac tatggaaatt gctggaaagt taattgggca tgatattgat
    15481 cataatgcgc tattaaataa aatgatggag aaggacccaa aaatgttgcc gtttcaaggt
    15541 tatgttttac aacatttcga acttatggat gatggattct gccaagttaa aataactgaa
    15601 gatgtattgg agcaattcgg tattcagcca aatgaagcat ctcagtttgt taatacaatt
    15661 gctgacatca aaggtttgaa aatatgggtg tttgcagttg atgagggtag tgaaataaga
    15721 tgtcgcttac gctctaaagg gcaattgatt attaatgata ttgcgcaaga ttttggtggc
    15781 ggtggccatc cgaatgcgtc aggagtttca gtgaacagct gggatgaatt tgagcaactt
    15841 gctacagctt tacgcacaaa acttaactaa tagaaaggag ccattcaatc atggtggcat
    15901 atttaaatat tcatacggct tatgatttgt taaattcaag cttaaaaata gaagatgccg
    15961 taagacttgc tgtgtctgaa aatgttgatg cacttgccat aactgacacc aatgtattgt
    16021 atggttttcc taaattttat gatgcatgta tagcaaataa cattaaaccg atttttggta
    16081 tgacaatata tgtgacaaat ggattaaata cagtcgaaac agttgttcta gctaaaaata
    16141 atgatggatt aaaagatttg tatcaactat catcggaaat aaaaatgaat tcaatggaaa
    16201 atgtttcatt tgaactattg caacaatttt catcgaattt gattatcatt tttaaaaatg
    16261 ttgcagacga acatcgtgac attgttcaag tttttgattc gcatgaagat acgtatttag
    16321 atcatcaaag tgttttagtt cagggtataa agcacgtatg gattcaaaat gtttgttacc
    16381 aaacacgtca agatgccgat acgatttctg cattagcagc tattagagac aatgcaaaat
    16441 tagacttaat tcatgatcaa gaagattttg gtgcacattt tttaactgaa aaggaaatta
    16501 aacaattaga tattaaccaa gaatatttaa cgcaggttga tgttatagct caaaagtgta
    16561 atgcagaatt aaaatatcat caatctctac ttcctcaata tcagacacct aacgatgaat
    16621 cagctaaaaa atatttgtgg cgtgtcttag ttacacaatt gaaaaaatta gaacttaatt
    16681 atgacgtcta tttagagcga ttgaaatatg agtataaagt tattactaat atgggttttg
    16741 aagattattt cttaatagta agtgatttaa tccattatgc gaaaacgaat gatgtgatgg
    16801 taggtccagg tcgtggttct tcagctggct cactggtcag ttatttacta ggtattacaa
    16861 cgattgatcc tattaaattc aatctattat ttgaacgttt tttaaaccca gaacgtgtaa
    16921 caatgcctga tatagatatt gactttgaag atacacgccg agaaagggtt attcagtacg
    16981 tccaagaaaa atatggcgag ctacatgtat ctggaattgt gactttcggt catctgcttg
    17041 caagagcggt tgctagggat gttggacgaa ttatggggtt tgatgaagtt acattaaatg
    17101 aaatttcaag tttaatccca cataaattag gaattacact tgatgaagca tatcaaattg
    17161 acgattttaa aaaatttgta catcgaaacc atcgacatga acgctggttc agtatttgta
    17221 aaaagttaga aggtttacca agacatacat ctacacatgc ggcaggaatt attattaatg
    17281 accatccatt atatgaatat gcccccttaa cgaaagggga tacaggatta ttaacgcaat
    17341 ggacaatgac tgaagccgaa cgaattgggt tattaaaaat agattttcta gggttgagaa
    17401 acttatcgat tattcatcaa atcttaatac aagtcaaaaa agatttaggt attaatattg
    17461 atatcgaaaa gattccgttc gatgatcaaa aagtgtttga attgttgtcg caaggagata
    17521 cgactggcat attccaatta gagtcagacg gtgtaagaag tgtattaaaa aaattaaagc
    17581 cggaacactt tgaagatatt gttgctgtaa cttctttgta tagaccaggt ccaatggaag
    17641 aaattccaac ttacattaca agaagacatg atccaagcaa agttcaatat ttacatccac
    17701 atttagaacc tatattaaaa aatacttacg gtgttattat ttatcaagag caaattatgc
    17761 aaatagcgag cacatttgca aacttcagtt atggtgaagc ggatatttta agaagagcaa
    17821 tgagtaaaaa aaatagagct gttcttgaaa gtgagcgtca acattttata gaaggtgcaa
    17881 agcaaaatgg ttatcacgaa gacattagta agcaaatatt tgatttgatt ctgaaatttg
    17941 ctgattatgg ttttcctaga gcacatgctg tcagctattc taaaattgca tacattatga
    18001 gctttttaaa agtccattat ccaaattatt tttacgcaaa tattttaagt aatgttattg
    18061 gaagtgagaa gaaaactgct caaatgatag aagaagcaaa aaaacaaggt atcactatat
    18121 tgccaccgaa cattaacgaa agtcattggt tttataaacc ttcccaagaa ggcatttatt
    18181 tatcaattgg tacaattaaa ggtgttggtt atcaaagtgt gaaagtgatt gttgatgaac
    18241 gttatcagaa cggcaaattt aaagatttct ttgattttgc tagacgtata ccgaagagag
    18301 tcaaaacgag aaagttactt gaagcactga ttttagtggg agcgtttgat gcttttggta
    18361 aaacacgttc aacgttgttg caagctattg atcaagtgtt ggatggcgat ttaaacattg
    18421 aacaagatgg ttttttattt gatattttaa cgccaaaaca gatgtatgaa gataaagaag
    18481 aattgcctga tgcacttatt agtcagtacg aaaaagaata tttaggattt tatgtttcgc
    18541 aacacccagt agataaaaag tttgttgcca aacaatattt aacgatattt aaattgagta
    18601 acgcgcagaa ttataaacct atattagtac agtttgataa agttaaacaa attcgaacta
    18661 aaaatggtca aaatatggca ttcgtcacat taaatgatgg cattgaaact ttagatggtg
    18721 tgattttccc taatcagttt aaaaagtacg aagagttgtt atcacataat gacttgttta
    18781 tagttagcgg gaaatttgac catagaaagc aacaacgtca actaattata aatgagattc
    18841 agacattagc cacttttgaa gaacaaaaat tagcatttgc caaacaaatt ataattagaa
    18901 ataaatcaca aatagatatg tttgaagaga tgattaaagc tacgaaagag aatgctaatg
    18961 atgttgtgtt atccttttat gatgaaacga ttaaacaaat gactacttta ggc
//
LOCUS       DAPDIM010000054        18826 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000054 DAPDIM010000000
VERSION     DAPDIM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 18826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18826
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.054"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(721..1989)
                     /gene="ilvA"
                     /locus_tag="RFE25_002062"
     CDS             complement(721..1989)
                     /gene="ilvA"
                     /locus_tag="RFE25_002062"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HDU2817102.1"
                     /translation="MTVKTTVSTKDIDEAFLRLKDIVKETPLQLDHYLSQKYDCKVYL
                     KREDLQWVRSFKLRGAYNAISVLSDEAKSKGITCASAGNHAQGVAYTAKKLNLNAVIF
                     MPVTTPLQKVNQVKFFGNSNVEVVLTGDTFDHCLAEALTYTSEHQMNFIDPFNNVHTI
                     SGQGTLAKEMLEQSKTDNVNFDYLFAAIGGGGLISGISTYFKTYSPTTKIIGVEPSGA
                     SSMYESVVVNNQVVTLPNIDKFVDGASVARVGDITFEIAKENVDDYVQVDEGAVCSTI
                     LDMYSKQAIVAEPAGALSVSALENYKDHIKGKTVVCVISGGNNDINRMKEIEERSLLY
                     EEMKHYFILNFPQRPGALREFVNDVLGPQDDITKFEYLKKSSQNTGTVIIGIQLKDHD
                     DLIQLKQRVNHFDPSNIYINENKMLYSLLI"
     gene            complement(2004..2576)
                     /gene="leuD"
                     /locus_tag="RFE25_002063"
     CDS             complement(2004..2576)
                     /gene="leuD"
                     /locus_tag="RFE25_002063"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDU2817103.1"
                     /translation="MAAIKPITTYKGKIVPLFNDNIDTDQIIPKVHLKRISKSGFGPF
                     AFDEWRYLPDGSDNPDFNPNKPQYKGASILITGDNFGCGSSREHAAWALKDYGFHIII
                     AGSFSDIFYMNCTKNAMLPIVLEKSAREHLAQYEEIEIDLPNQTVSSPDKRFHFEIDE
                     TWKNKLVNGLDDIAITLQYESLIEKYEKSL"
     gene            complement(2577..3944)
                     /gene="leuC"
                     /locus_tag="RFE25_002064"
     CDS             complement(2577..3944)
                     /gene="leuC"
                     /locus_tag="RFE25_002064"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDU2817104.1"
                     /translation="MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGL
                     RLQNRKLRRPDLTFATLDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSD
                     EQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQT
                     KPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTI
                     CNMAIEGGAKYGIIQPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELD
                     VSTLEPQVTWGTNPEMGVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLG
                     SCTNARLSDLIEASHIVKGNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWR
                     EPGCSMCLGMNPDQVPEGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAIHGKFVDV
                     RKVVV"
     gene            complement(3958..5004)
                     /gene="leuB"
                     /locus_tag="RFE25_002065"
     CDS             complement(3958..5004)
                     /gene="leuB"
                     /locus_tag="RFE25_002065"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDU2817105.1"
                     /translation="MTYNIVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFG
                     GASIDTFGEPLTEKTLNACKRADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFAN
                     IRPTTVVKGASSLSPLKEERVEGTDLVIVRELTSGIYFGEPRHFNNHEALDSLTYTRE
                     EIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVSQLYPEVTVNHLLVDA
                     CSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRLYEPIHGS
                     APDIAGKNVANPFGMILSLAMCLRESLNQPDAADELEQHIYNMIEHGQTTADLGGKLN
                     TTDIFEILSQKLNH"
     gene            complement(5007..6536)
                     /locus_tag="RFE25_002066"
     CDS             complement(5007..6536)
                     /locus_tag="RFE25_002066"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDU2817106.1"
                     /translation="MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIE
                     AGFPASSTGSFKSVQAIAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIAT
                     SPIHLEHKLKMSQEDVLASIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVD
                     AGATVINIPDTVGYSYHDEYAHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAI
                     EGGARRIEGTVNGIGERAGNAALEEVALALYVRNDHYGAQTALNLEETKKTSDLISRY
                     AGIRVPRNKAIVGQNAFSHESGIHQDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGK
                     HAFSEKLKALGYNIDKEAQIDLFKQFKTIADKKKSVSDRDIHAIIQGSEHEHQALYKL
                     ETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYR
                     INSVTEGTDAQAEVHVNLLIEGKTVNGFGIDHDILQASCKAYVEAHAKFAAENVEKVG
                     N"
     gene            complement(6566..7585)
                     /gene="ilvC"
                     /locus_tag="RFE25_002067"
     CDS             complement(6566..7585)
                     /gene="ilvC"
                     /locus_tag="RFE25_002067"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDU2817107.1"
                     /translation="MEEFIMTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDN
                     GYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNL
                     EKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQD
                     ASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETL
                     VEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVK
                     ENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKS
                     KSIEK"
     gene            complement(7707..7961)
                     /locus_tag="RFE25_002068"
     CDS             complement(7707..7961)
                     /locus_tag="RFE25_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDU2817108.1"
                     /translation="MTRILKLQVADQVSTLNRITSAFVRLQYNIDTLHVTHSEQPGIS
                     NMEIQVDIQDDTSLHILIKKLKQQINVLTVECYDLVDNEA"
     gene            complement(7961..9730)
                     /gene="ilvB"
                     /locus_tag="RFE25_002069"
     CDS             complement(7961..9730)
                     /gene="ilvB"
                     /locus_tag="RFE25_002069"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDU2817109.1"
                     /translation="MSKTQHEVNQNIDPLKMAESLELEQLNEKTLNDMRSGSEVLVEA
                     LLKENVDYLFGYPGGAVLPLYDTFYDGKIKHILARHEQGAVHAAEGYARVSGKTGVVV
                     VTSGPGATNVMTGITDAHCDSLPLVVFTGQVATPGIGKDAFQEADILSMTSPITKQNY
                     QVKRVEDIPKIVHEAFHVANSGRKGPVVIDFPKDMGVLATNVDLCDEINIPGYEVVTE
                     PENKDIDTFISLLKEAKKPVVLAGAGINQSKSNQLLTQFVNKHQIPTVTTLLGLGAVP
                     YEDTLFLGMGGMHGSYASNMALTECDLLINLGSRFDDRLASKPDAFAPNAKIVHVDID
                     PSEINKVIHVDLGIIADCKRFLECLNDKNVETIEHSDWVKHCQNNKQKHPFKLGEEDQ
                     VFCKPQQTIEYIGKITNGEAIVTTDVGQHQMWAAQFYPFKNHGQWVTSGGLGTMGFGI
                     PSSIGAKLANPDKTVVCFVGDGGFQMTNQEMALLPEYGLDVKIVLINNGTLGMVKQWQ
                     DKFFNQRFSHSVFNGQPDFMKMAEAYGVKGFLIDKPEQLEEQLDAAFAYQGPVLIEVR
                     ISPTEAVTPMVPSGKSNHEMEGL"
     gene            complement(9758..11446)
                     /gene="ilvD"
                     /locus_tag="RFE25_002070"
     CDS             complement(9758..11446)
                     /gene="ilvD"
                     /locus_tag="RFE25_002070"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDU2817110.1"
                     /translation="MRSDMIKKGDHQAPARSLLHATGALKSPTDMNKPFVAICNSYID
                     IVPGHVHLRELADIAKEAIREAGAIPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADA
                     AETVINAHWFDGVFYIPNCDKITPGMILAAMRTNVPAIFCSGGPMKAGLSAHGKALTL
                     SSMFEAVGAFKEGSISKEEFLDMEQNACPTCGSCAGMFTANSMNCLMEVLGLALPYNG
                     TALAVSDQRREMIRQAAFKLVENIKNDLKPRDIVTREAIDDAFALDMAMGGSTNTVLH
                     TLAIANEAGIDYDLERINAIAKRTPYLSKIAPSSSYSMHDVHEAGGVPAIINELMKKD
                     GTLHPDRITVTGKTLRENNEGKEIKNFDVIHPLDAPYDAQGGLSILFGNIAPKGAVIK
                     VGGVDPSIKTFTGKAICFNSHDEAVEAIDNRTVRAGHVVVIRYEGPKGGPGMPEMLAP
                     TSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAASGGPIALIEDGDEITIDLTN
                     RTLNVNQPEDVLARRRESLTPFKAKVKTGYLARYTALVTSANTGGVMQVPENLI"
     gene            complement(11764..11919)
                     /locus_tag="RFE25_002071"
     CDS             complement(11764..11919)
                     /locus_tag="RFE25_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817111.1"
                     /translation="MIIHCSIVSNFIFNLYIVTNFNLNFLSLKQIIYSKLIVRKFKIF
                     VDILKQI"
     gene            11957..12418
                     /gene="tsaE"
                     /locus_tag="RFE25_002072"
     CDS             11957..12418
                     /gene="tsaE"
                     /locus_tag="RFE25_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDU2817112.1"
                     /translation="MIKINNLDEMNQFAMFLVEQLKSGDLILLNGDLGAGKTTLTQFI
                     GKALGVRRTINSPTFNIIKSYRGKNLKLHHMDCYRLEDSDEDLGFDEFFEDQAITVIE
                     WSQFIKDLLPATHLSINISTISENTRQIELFAQGEHYEQIKEAIIHEFAAH"
     gene            12399..13061
                     /gene="tsaB"
                     /locus_tag="RFE25_002073"
     CDS             12399..13061
                     /gene="tsaB"
                     /locus_tag="RFE25_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDU2817113.1"
                     /translation="MNSLLIDTSNQPLSVALMQNDEVLAEITTDSKQNHSVQLMPAIS
                     QLFEQSKIAKQQLDAIIVAEGPGSYTGLRIGVTVAKTLAYALDVKLYGVSSLKALAAT
                     IDHTDKLLVPVFDARRQAVYTGIFQWQNGQLVTILEDQYMSIEALRAFLEDLNQPFIY
                     IGKDTIKLQDELQGEVIAQLPNASVMYQLIDKPTDVHTFTPKYHKLAEAERNWINSQK
                     NN"
     gene            13034..13498
                     /gene="rimI"
                     /locus_tag="RFE25_002074"
     CDS             13034..13498
                     /gene="rimI"
                     /locus_tag="RFE25_002074"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDU2817114.1"
                     /translation="MDQQSKEQLNIREMTKEDVPQVFDLERRSFNDSSWTIDAFYHEI
                     EQNNFAKYFVLEFEQQIIGYLGLWIVIDQAQITTVAIDDNYRGYGLGQMLLKYGINYA
                     SHTCDVMSLEVRVNNKVAQHVYENLGFQYGGKRKNYYGEGEDAMVMWVNLND"
     gene            13491..14516
                     /gene="tsaD"
                     /locus_tag="RFE25_002075"
     CDS             13491..14516
                     /gene="tsaD"
                     /locus_tag="RFE25_002075"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDU2817115.1"
                     /translation="MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFG
                     GVVPEVASRHHVEGITTTINEALVDADVSMEDIDAIAVTEGPGLIGALLIGVNAAKAL
                     AFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGET
                     RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKS
                     AVINQLHNQRQKNIPIIEANVATSFQNSVVEVLTFKAIQACKEYSVQRLIVAGGVASN
                     KGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQGRFADLALNGHSNID
                     LEEYSAE"
     gene            complement(14831..16441)
                     /locus_tag="RFE25_002076"
     CDS             complement(14831..16441)
                     /locus_tag="RFE25_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MutS family DNA mismatch repair protein"
                     /protein_id="HDU2817116.1"
                     /translation="MSTNQTFLIFVIAIILLTSVIGIVGRYMSRQRLLKSMETLWQTI
                     SPLEAFIRPNSHFDYEYKLYKEKFESHSLVDDKTWSDLNMNAIFHKMNYNLTAIGEMK
                     LYACLRGMLSITNKSLLSLFNDNAEFRKNVTYHLALIGKTVYPTFPDQITPVKRQNIL
                     FLCPFLPVISFAVIFINSQVGILLFLMSCLFNIILSATLKRTYEDDLKSIFYASNVLK
                     QGYTISKIKHAPQPEVNFKQFRTARHLTSVLAEVNDEDIGAMVIKLVKLIFMLDYVLF
                     HSIQKSYTTHMNELKNCFDYIAELDNHYALAMYRRTLECYTEPQIDDTNDGIVFSELT
                     HPLIADAVANDFSLSQNILLTGSNASGKSTFMKSIAINIILASAIQTVTASKFVYQPG
                     IVFTSMANADDVLSGDSYFMAELKSIKRIVEIPDNQKIYCFIDEIFKGTNTTERIAAS
                     ESVLSFLHEKSNFRVIAATHDIELAELLKQRYENYHFNEVIENNNIHFDYKIKPGKAN
                     TRNAIELLKITSFPAKIYERAKDNVSNG"
     gene            16530..16658
                     /locus_tag="RFE25_002077"
     CDS             16530..16658
                     /locus_tag="RFE25_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817117.1"
                     /translation="MIKTMSIENMRTYQQRVNNLWIKGVDNVIYCGYQVGKQKINN"
     gene            complement(16803..18731)
                     /gene="abc-f"
                     /locus_tag="RFE25_002078"
     CDS             complement(16803..18731)
                     /gene="abc-f"
                     /locus_tag="RFE25_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HDU2817118.1"
                     /translation="MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKST
                     LMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSNATVFEEMSKPFEHIKRMESLIK
                     EETDWLSKHANDYDSDTYKTHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDF
                     NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVI
                     ISHDRYFLDKIVTQIYDVALGDVKRYVGNYEEFIQQRDLYYQKRMQEYESQQAEIKRL
                     ETFVEKNITRASTSGMAKSRRKILEKMERIDKPMLDAKSANIQFGFDRNTGNDVMHVK
                     NLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGDITFGANL
                     QIGYYDQKQAEFKSSKTILDYVWDQYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGG
                     EKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQ
                     LANKVFDLTIDGGKMYLGDYQYYIEKVEEAEALKAHQEEQSVNVQAHKKSMEQSSYHN
                     QKEQRREQRKLERQISECENEIETLETTILQIDEQLTQPEVYNNPQKANELAIQKQDS
                     EQKLEHAMSKWEELQQKL"
BASE COUNT         5943 a         3292 c         3211 g         6380 t
ORIGIN      
        1 gttgagaccg caggtctctt ttttttatgt ctaaaacgtc aaaataaaag caaacacaaa
       61 gaaagatggc ttggcgaagt gaaaacgttt gaatctgacg aaacaagaaa agagcgcaac
      121 gagtttagta gagctaaatg agtaagcgag agccgaagga gaggaaagaa gcaagcgatt
      181 gtcacaagtc aagaaaggtc tttagcgacg atggtagcaa acttacgttc cgctagagta
      241 gaacgttgcc aggcaagttg agaccgcaag gtctcttttt ttatgtctaa aacgtcaaaa
      301 taaaagcaaa cacaaagaaa gatggcttgg cgaagtgaaa acgtttgaat ctgacgaaac
      361 gagaaaagag tgcaacgagt ttagtagagc taaatgagta agcgagagcc gaaggagagg
      421 aaagaagcaa gcgattgtca caagtcaaga aaggttctta gcgacgaagg tagccaactt
      481 acgttccgct agagtagaac gttgccaggc aaaaagtgga tgcgatgagc cgcattgaga
      541 ccgcaaggtc tcttttttta tgtctaaagt tacatagtaa aaagcaaaca caaagaaaga
      601 tggcttggcg aagtgaaaac gtttgaatct gacgaaacga gaaatgtaaa gtataataaa
      661 aagcagtcat aagatgattt caattagaaa tcaatttatg actgtttttc ttactatgtg
      721 ttaaattaac aatgaatata acatcttatt ttcattaata taaatattgg aaggatcgaa
      781 atgatttaca cgttgtttga gttgtattaa atcatcatga tctttaagtt gaataccaat
      841 aatgacagta cctgtatttt gagaagattt ttttaagtat tcaaattttg taatatcgtc
      901 ttgtgggcct aaaacatcat ttacaaattc tcttaatgca ccagggcgtt gagggaagtt
      961 taaaataaaa taatgtttca tttcttcata taataaagaa cgttcttcaa tttccttcat
     1021 acgattaata tcattattac caccactaat gacacaaaca acagttttac ccttaatgtg
     1081 gtctttgtag ttttcaagag cactcacact taatgcgcca gcaggttctg ctacaattgc
     1141 ttgttttgaa tacatgtcta aaatcgtaga acaaactgca ccttcatcta cttgaacgta
     1201 atcatctaca ttttcttttg caatttcaaa tgtaatatcg ccaactctag ctacagatgc
     1261 accgtccaca aatttatcga tattaggcaa tgtgactacc tgattattta cgacaacaga
     1321 ttcatacata ctacttgcac ctgaaggttc aacacctata attttcgtag taggtgaata
     1381 ggttttaaag taagtactaa tacctgaaat taatccacca ccaccaatag cggcaaataa
     1441 ataatcaaag ttaacattgt cagtctttga ttgttctagc atttctttag caagcgtacc
     1501 ttgtccagaa attgtatgaa cattattgaa tggatctata aagttcattt gatgttcact
     1561 tgtataagtt aaagcttcag ctaaacagtg atcaaatgta tcaccagtga gtacaacttc
     1621 aacgttacta tttccaaaga actttacttg atttaccttt tgtaaaggtg tagtgactgg
     1681 cataaagata acagcgttta aattaagttt tttagctgta taggcaacac cttgagcatg
     1741 attacctgca ctcgcacatg taataccttt acttttagct tcatctgata aaacagaaat
     1801 agcgttgtaa gcacctctta atttaaaaga acgtacccat tgtaaatctt ctcgttttaa
     1861 ataaacttta caatcatact tttgagataa gtaatggtct aattgtaaag gtgtttcttt
     1921 gacaatatct ttaagtctta aaaatgcttc atcgatatct ttcgtagaaa ctgttgtttt
     1981 gactgtcata atattcaact cccttaaagt gatttttcat atttttctat taatgattca
     2041 tattgtaggg tgattgcaat gtcatctaag ccatttacaa gtttattttt ccaagtttca
     2101 tcaatttcaa aatggaaacg cttgtctggt gatgacacag tttgatttgg taaatctatt
     2161 tcaatttcct catattgtgc aagatgttca cgagcacttt tttctaaaac gataggcaac
     2221 atcgcatttt tagtgcaatt catataaaat atgtcactga aacttcctgc aataataata
     2281 tgaaaaccat agtccttaag agcccaagca gcatgttcac gacttgaacc acatccaaaa
     2341 ttatctccag taattaaaat agaagcccct ttatattgtg gtttgttagg attgaaatca
     2401 ggattatctg aaccatcagg taagtaccgc cattcatcaa aagcaaatgg accaaagcca
     2461 ctttttgaaa tacgctttaa gtgtacctta ggaatgattt ggtctgtatc gatattgtcg
     2521 ttgaagagag ggactatttt acctttatat gttgtaatag gtttgattgc tgccatttaa
     2581 acaaccacct ttcttacgtc cacaaattta ccatgaatag ctgctgctgc catagcaggg
     2641 gatactaaat gtgttcttgc acctttgcct tgtcgtcctt caaagtttcg attacttgta
     2701 gatgcacaat gtacgccctc aggtacttgg tcaggattca tgcctaaaca cattgaacat
     2761 cctggttcac gccattcaaa tcctgcattt ttaaagatag tatctagacc taatttttct
     2821 gcttcttttt ttactgtacg agaacctggt acgacaatag ctgtaatatt tggatgaact
     2881 ttatttcctt taacaatatg actagcttca atcaaatctg atagtctagc atttgtacat
     2941 gaaccgagaa aaacataccc taagtcgatg tcttcagctt tttgacctgg ttctaacccc
     3001 atataatcat acgcacgttg atcgttgata tcattgattt cagggaatgg ttcactgaaa
     3061 ttaacaccca tttcaggatt agttccccat gtcacttgtg gttctaatgt tgaaacatca
     3121 agttcaatta cacgatcaaa tatcgcgtcg tcatcagaat atagctcacg ccacttatca
     3181 actgatttag cgaagttatc ggcaaatggt ctccctttaa catattcaaa tgttatatca
     3241 tcaggttgga ttatgccgta tttggcacca ccttcgatag ccatgttaca aatagtcatt
     3301 cgaccgtcca ttgaaaggtt tttaattgtt tcgccagtaa attccaaagc atagcctgta
     3361 ccaaaatcaa caccatacgt tttaattaaa tgcagaataa tgtccttagc atagacgcct
     3421 gttggtaagg taccattaat atcgattttt aagtttttgg gttttgtttg ccatagcgtt
     3481 tgagttgcga aaacatgttc aacttcactt gttccaattc caaatgcaat agcaccaaat
     3541 gctccatgtg ttgctgtgtg agagtcacca caaacgattg ttttgccggg ctgtgtaagt
     3601 cctgtctcag gtcctaccat gtgaacaata ccttgttcat cagagcccat atcaaaaata
     3661 tgcaccccaa aatctatggc gtttttttgt aatgttgtga tttgtttgtt tgcaatttca
     3721 tctttaatat tgaaaatatc aatagtagga acattgtgat cgagtgttgc aaatgttaaa
     3781 tctgggcgtc ttaattttct gttttgaagc ctaagtcctt caaatgcttg aggagaagta
     3841 acttcatgta taaggtgtaa atcaatgtat aatagttgcg gttcgcccaa tttcccgtat
     3901 aacacatgtc tgttccacac cttgtcaaat aatgtttgac ccatttacat ctccccctta
     3961 gtgattcaat ttttgagata gaatttcgaa aatatcagta gtattcaatt tgccgcctaa
     4021 atctgctgtc gtttgcccat gttcaatcat gttataaata tgttgttcta attcatctgc
     4081 agcatctggt tgatttaagc tttcacgtaa acacatcgct aaagatagaa tcattccaaa
     4141 tggattggca acgtttttac ctgcaatatc tggtgctgat ccatgaatag gctcatacaa
     4201 tcttggacca tcgttactaa aactagcaga aggtgataaa ccaagtgaac caggaatcac
     4261 tgaagcttca tcacttaaaa tatcgccaaa taagttttca catacgatga cgtcaaattg
     4321 ttttggattt gtgattaaat gcatactaca agcatcaaca agtaagtgat ttactgttac
     4381 ttctggatat aattgactta cttcatttac gactttgcgc cacaatttac tagaagctaa
     4441 tacattttct ttatcaactg atgttagttt tcctcgtctt gaagcggcca atttaaatgc
     4501 tacgtgaaca atgcgttcta tttcttctct tgtataagta agagaatcta aggcctcgtg
     4561 attattaaaa tgtctaggtt ctccaaaata aataccactt gtcaattcac ggactataac
     4621 taaatctgtg ccttcaacgc gttcttcctt taaaggtgat aaagaactag cgcctttgac
     4681 aacggtagtg gggcgaatat ttgcaaataa atttaaggat ttacgcaatt ttaataatcc
     4741 ttgttctggt cgattgttag gatctgtcca tttaggtcca ccgattgcac ccagtaaaat
     4801 agcatctgct cttttacacg catttaaggt tttctcagtt aaaggctcgc cgaatgtatc
     4861 aatagaggca ccaccaaatt cgtggtgctc tatttgataa ttaaagttat atttattact
     4921 tataatttca agcaatgata gagatccgtt caaaatttct ggaccgattc catcaccagg
     4981 tagggcaaca atgttataag tcataattaa ttacctacct tctcaacatt ttcagctgca
     5041 aatttagcat gtgcttctac gtatgcttta caagaggctt gtaaaatatc atgatcaata
     5101 ccaaagccat tgacagtctt accttcaatc aataaattta catgtacttc tgcttgggca
     5161 tcagtacctt cagtgacaga attaatacga taatcaatta attctgtttc tttctggaaa
     5221 atacgatcaa ctgcattgta aattgctacg attgaaccag taccaatact tgaatcctgg
     5281 taaatatgac cctctttatc tttaacaaca acaacagcac tttgaaggcc gctagagaca
     5341 tattgtagtt gtagtgtttc caatttataa agtgcttgat gctcatgctc agaaccttga
     5401 ataatcgcat gaatatctct atctgaaaca gatttctttt tgtccgcaat ggtcttgaat
     5461 tgtttaaata aatctatttg cgcttcttta tcaatgttat aacctaatgc ttttaacttc
     5521 tctgagaagg cgtgtttacc agataatttt cctaatggaa gttcagtcgt gcttacacca
     5581 acaagttgag gtgtcataat ttcatatgtt tcacgatgtt ttaatacgcc atcttggtga
     5641 atacctgatt catgactaaa tgcattttgg ccaacaattg ctttatttct aggcactcga
     5701 atacctgcat atcttgaaat taaatccgat gtttttttag tttcttcgag attaagggca
     5761 gtttgagcac cataatgatc atttcgaacg tatagtgcaa gcgcgacttc ttcaagtgct
     5821 gcattacctg ctcgttcacc aataccattt acagtgcctt caattcgtct cgcaccgcct
     5881 tcaattgcag ctaaactatt tgaaacagcc attcctaaat cgtcatggca atgagcacta
     5941 taaataattt catttgaaga tgttacagat tctgttaagg ttttgaaaat atgtgcatat
     6001 tcatcatggt aactgtagcc gactgtatca ggaatattaa taactgtagc tccagcgtca
     6061 acggcagttt gtacacattt cactaagaat ggtaattcag tacgcgttgc atcttcaggt
     6121 gaaaattgaa caacgtcaaa taattgtttc gcgtatgtga catgttcttt aatagatgct
     6181 aaaacgtctt cttgagacat tttaagttta tgttcaagat gaataggtga tgttgctata
     6241 aaaacatgca cgaccggctt cgctgcatct tttgttgctt catatacagc atcgatgtca
     6301 gattttttac atctagctaa accacataca gccgttgttg ttaatgtttg tgcaattgct
     6361 tgaacagatt taaagctacc tgtacttgaa gcaggaaatc cagcttcaat aacatctaca
     6421 ccccattttt ctaattgcaa tgcaatacgc aagcgttcat caaaagtaaa attcactcct
     6481 ggtgtttgtt caccgtctct tagtgtcgta tcaaaaattt gaatatgact actcatattt
     6541 aacaactcct cattgtaggt ctatcttatt tttcaatgct tttagattta ataaaaggca
     6601 tcatttcgcg taattcacga ccaacttttt caatttgatg accatgttgt tcttcgcgta
     6661 atttataaaa ttctttgaat ccatttttat tgtcttcgat aaagcgatta ctgaagttac
     6721 cattttggat atcagttaat acagctttca tattttcttt aacatctggt gtgataacac
     6781 gtggtcctga aacatagtca ccaaattcag cagtatttga aattgagtaa cgtacatttt
     6841 ccataccgcc ttcatacatc aaatcaacga ttaatttcat ttcatgtaat acttcaaaat
     6901 aagctaattc tggttgataa cccgcttcta ctaatgtttc aaagccactt tgaattaatt
     6961 tcgatacacc accgcaaagt actgcttgtt caccaaataa atctgtctca gtttcttctt
     7021 taaatgttgt ttcaataaca cctgcacgag ttgcaccaat accttttgca taacttaaag
     7081 caatattacg tgcttgacct gaagcgtctt gttgaatacc aaatagtgat ggtacagcag
     7141 aaccttcaac aaatgtacgt ctaactaaat gacccggtcc tttaggagct actaaaaata
     7201 catcaacatc agctggtggt tgaataacac caaaatgaat gttaaagcca tgagcaaatg
     7261 caagcgcatt atgtttttct aaatttggtt caatttcgtt tttgtataca tcaccttgaa
     7321 tttcatcagg taatagcacc ataattacat cagcttgctt aactgcttct gcaacaggga
     7381 acacatcaaa tccatcttct ttagccttgt caaaagaacg acctgggcga ataccgatga
     7441 ctacatcata tccattgtct tttaagtttt gtgcatgcgc gtggccttgt gatccataac
     7501 ctactactgc aatttttttg ccttgtaaag cgtccgtttt tacgtcttga tcataataaa
     7561 ctgttgtcat aataaattcc tccaaataat taaatgtttt gtttttcgaa aattctgaaa
     7621 tataactttg taatagtggc agatgttaac tagcagccta tgatatatct ataactaatt
     7681 agcgcatcat tgcctttgtc ttaaaattaa gcttcgttat caacaaggtc gtagcattca
     7741 accgttaaaa cattaatttg ttgttttaat tttttaatta atatatgaag tgatgtatca
     7801 tcttgaatat cgacttgaat ttccatgtta gaaatcccag gttgttcaga atgtgtaaca
     7861 tgtaatgtat cgatattata ttgtaggcga acaaaagcac ttgtaattcg atttagcgtg
     7921 ctgacttgat ccgcaacttg taatttaaga attcttgtca ttataagccc tccatttcat
     7981 gatttgattt gccactcgga accattgggg ttacagcttc agtaggggaa atacgaacct
     8041 caattaaaac tggtccttga taagcaaacg ctgcatctaa ttgttcttcc agttgttctg
     8101 gcttatcgat taagaaacct ttgacgccat atgcttctgc cattttcata aaatcaggtt
     8161 gaccattaaa tactgagtgt gagaagcgtt gattaaagaa cttatcttgc cattgtttaa
     8221 ccatacctaa tgttccatta ttgattagta cgattttgac atctaaacca tattcgggta
     8281 aaagtgccat ttcttggttt gtcatttgga aaccaccgtc accgacgaaa catacgactg
     8341 ttttatcagg attagctaat ttggcaccaa ttgacgaagg aataccgaat cccattgttc
     8401 ctaaaccacc gcttgtaacc cattgtccgt gatttttaaa tggataaaat tgagctgccc
     8461 acatttgatg ttgtcccacg tctgtagtaa caattgcttc accatttgta attttgccga
     8521 tatattcgat tgtttgttgt ggcttacaaa atacttgatc ttcttcacca agtttaaatg
     8581 ggtgtttctg cttattattt tgacaatgtt taacccagtc actgtgttct atagtctcaa
     8641 catttttatc atttaaacat tctaaaaatc ttttacagtc tgcaataata cctaaatcta
     8701 catgaataac tttattgatt tctgaaggat caatatctac atgtacaatt ttggcgttag
     8761 gtgcaaaggc atcaggtttg cttgctaatc tatcatcgaa gcggctacct aaattaatga
     8821 gtaaatcaca ctcagttaat gccatgttac tagcataaga accatgcata cctcccatac
     8881 ctaaaaatag tgtatcctca taaggtacag cacctagacc tagtaaagta gtaactgttg
     8941 ggatttgatg tttattaaca aactgtgtta ataattgatt tgattttgat tgattaatac
     9001 ctgcgccggc taatacgaca ggctttttcg cttcttttaa aagtgagatg aaagtgtcaa
     9061 tgtctttatt ttctggttct gtaacaactt cataacctgg aatattgatt tcgtcgcata
     9121 aatccacatt tgtagctaaa acacccatat cttttggaaa atcaatcact acaggacctt
     9181 tgcgtccaga attagctaca tggaaagctt cgtgtacgat tttagggata tcttcaacac
     9241 gtttcacttg ataattttgt tttgtaattg gtgaagtcat agatagaata tccgcttctt
     9301 ggaatgcatc tttaccaatg cctggtgtag caacttgtcc agtgaataca actagaggta
     9361 aagagtcgca atgtgcatcc gtaatacctg tcattacatt agttgcacct ggaccgcttg
     9421 taactacaac gacgccagtt ttaccagata cacgtgcata accttctgca gcatgaacag
     9481 caccttgttc gtgtcttgct aaaatatgtt tgattttacc atcataaaat gtgtcgtata
     9541 aaggtagtac ggcaccacca ggataaccga ataaataatc cacattttct ttaagtagag
     9601 cttctactag cacttctgat cctgaacgca tgtcatttaa agttttttca tttagttgtt
     9661 caagttcaag tgattcagcc atttttaaag gatcaatatt ttggtttact tcatgttgag
     9721 ttttagacat tttaaccatc tccaatataa aaataaatta aattaaattc tcagggactt
     9781 gcatgacgcc acctgtattt gcgctagtta ctagggcagt ataacgagct agataacctg
     9841 tttttacttt cgctttaaac ggtgttaaag attctcggcg acgcgctaga acatcttcag
     9901 gctggtttac gtttaatgta cgatttgtta aatcaatagt aatctcatct ccatcttcaa
     9961 ttaaggcaat tggtccacca gatgcagctt caggggaaat atgaccaact gcaatacctc
    10021 ttgtggcacc ggaaaaacgc ccatcagtaa ttaatgcaac atctttacct aagccgcgac
    10081 caacaataga ggaagtaggt gctaacattt caggcatacc tggtccacct ttaggtcctt
    10141 catatctaat gacaacgacg tggcctgcac gaacggtacg attgtctatt gcttcaacag
    10201 cttcatcatg cgaattgaaa caaattgctt tcccagtaaa tgttttgata gatggatcaa
    10261 cgccgccaac tttaataact gcgcctttag gggcgatatt accaaataag atagataaac
    10321 cgccttgtgc atcatatggt gcatcaagag ggtgaatgac atcaaagttc ttaatttctt
    10381 tgccttcgtt attttcacgt aacgttttgc cagtaactgt gattctatct gggtgtaacg
    10441 tgccatcttt cttcatcaat tcattaataa ttgctgggac gccaccagct tcatgcacat
    10501 catgcattga atacgatgaa ctaggtgcta tttttgataa atatggcgtg cgtttggcaa
    10561 tagcattaat gcgctctaag tcataatcaa taccagcttc attggcaatg gctaacgtat
    10621 gcagtaccgt gtttgttgaa ccacccatag ccatatcaag tgcaaatgca tcatcaattg
    10681 cttcgcgagt aacgatatca cgtggtttta aatcattttt aatattttca actaatttaa
    10741 aagctgcttg gcgaatcatt tcgcgtcgct gatcactgac tgcaagtgca gtaccgttgt
    10801 atggtaatgc tagacctaaa acttccatca aacagttcat tgaatttgca gtaaacatcc
    10861 cagcacatga accacaagta gggcaggcat tttgttccat atctaaaaat tcttctttag
    10921 aaatcgatcc ttctttaaat gcgccgactg cttcaaacat tgatgaaagt gttaatgctt
    10981 ttccatgtgc agataagcca gctttcattg gtccaccaga gcaaaagata gctggtacgt
    11041 ttgtcctcat ggctgctaaa atcataccgg gtgtaatctt gtcacaatta ggaatgtaaa
    11101 atacgccgtc aaaccaatga gcgttaatta cagtttcagc tgcatctgca ataatttcac
    11161 gtgatggtag agaatatcgc attccgatat gtcccatagc tattccatca tcaacaccaa
    11221 ttgtattgaa ttcaaatgga atggcaccgg cttctctaat tgcttcttta gctatatctg
    11281 caagctctct caagtgaaca tgtccaggaa caatatcaat ataagagtta caaatagcta
    11341 caaatggttt gttcatatca gttggacttt ttagcgcgcc cgtggcatgt aaaagacttc
    11401 ttgctggtgc ttggtgatct ccttttttga tcatgtcgct tcgcatagta aattcccccg
    11461 taaattttaa tgattaatca tgttttatag taataaaaat aagtaattga aagataaaac
    11521 ataaaaaaac gtcccaatat tattgggacg tttacaagtc ccattcaaac agaaatagga
    11581 cttaaagcgt ttagtaaata tttactaacg ttcgagtcct aaagagtata ataaaataat
    11641 aatatttgaa gttgtcggtt gatgttcagt atattgatta agcattttat tatactcctt
    11701 ccgtgaatgg tatatatcac tttaatagtt agaattgtct aaaaatttga taaatttaat
    11761 ttactatatc tgctttagta tgtcaacaaa tattttaaat tttcttacaa ttaactttga
    11821 atagataatc tgtttcaaag ataagaaatt taagttgaaa tttgttacaa tataaaggtt
    11881 aaatataaag ttagatacga ttgaacaatg gataatcatt tttatgaatg aaaagcataa
    11941 tataggagaa tcaacattga taaagataaa taatttagat gaaatgaatc aatttgctat
    12001 gtttttagtt gagcaattga aaagtggtga tttgatttta cttaacggag atttaggagc
    12061 aggtaaaaca acgttaacgc aatttatagg aaaagctctt ggtgtaagac gtacgattaa
    12121 ttccccgaca tttaacatca ttaaatcata taggggtaaa aatttaaaat tgcatcatat
    12181 ggattgttat cgcttagaag attctgatga agatttaggg tttgatgaat ttttcgaaga
    12241 tcaggcaatt actgttattg aatggagtca atttataaaa gatttacttc cagcgacgca
    12301 tttatctatt aacatttcaa caatatctga aaatacaaga caaattgagt tgttcgcgca
    12361 aggagaacat tatgaacaaa ttaaggaggc aattatccat gaattcgctg ctcattgata
    12421 catcgaatca accattatca gtagcattga tgcaaaacga tgaagtttta gctgaaataa
    12481 ctacggattc taaacaaaat cattcagtgc aattaatgcc tgcgattagt cagctatttg
    12541 agcagagcaa aatagctaaa cagcaattag atgcgattat tgttgctgaa ggtcctggtt
    12601 catatactgg cttacgtatc ggtgttactg ttgctaaaac attagcgtat gcgttagatg
    12661 ttaaattata tggtgtttca tcattaaagg cattggcagc aacaatcgat catactgata
    12721 aattattggt tcctgtgttt gatgcaagac gacaagcagt ttatacaggc atattccagt
    12781 ggcaaaatgg tcaattagtg actattttag aagatcaata tatgtcgata gaggcattgc
    12841 gagctttttt agaagattta aaccaaccat ttatttatat tgggaaagat actataaaat
    12901 tacaagatga attacaaggt gaagtgattg cgcagctacc aaatgcatca gtcatgtatc
    12961 aattgataga taaacctaca gacgtacata catttactcc taaataccat aaattagctg
    13021 aggcggaacg aaattggatc aacagtcaaa agaacaatta aacattagag agatgactaa
    13081 agaagatgtg ccacaagtct ttgatcttga gcgtcggagt ttcaatgaca gttcttggac
    13141 aattgacgca ttttatcatg aaatagagca aaataacttt gcgaaatatt ttgtcttaga
    13201 atttgaacaa caaattattg gttatttagg tttatggatt gttatcgatc aagctcaaat
    13261 tacaacagtt gcaatcgatg ataattatag aggctatggt ttaggtcaaa tgcttttaaa
    13321 atacggaata aactatgcaa gtcacacttg tgatgtgatg agtttagaag taagagttaa
    13381 taataaagtg gcacaacatg tatatgaaaa tttaggattt caatatggtg gtaaacgtaa
    13441 aaattattat ggtgaaggtg aggacgcaat ggttatgtgg gtgaatttaa atgactaaag
    13501 atatattaat actagctgtt gaaacaagtt gtgatgaaac aagcgttagt gttataaaaa
    13561 atggcagaga tattttatca aatacagttt taagtcagat tgaaagtcat aaacgatttg
    13621 gcggtgtcgt tcccgaagtg gcaagtagac atcacgttga aggtataaca acaacaataa
    13681 acgaggctct agtggatgcc gatgtatcaa tggaagatat tgatgccata gcggttacag
    13741 aaggccctgg actaattggt gcgttactaa taggtgttaa tgcagccaaa gcattggcat
    13801 ttgcttacga taagccactt attcctgttc atcatattgc aggacatata tatgctaatc
    13861 acatagaaga gccattaaca ttcccgctaa ttgcacttat tgtttcaggt ggacatactg
    13921 aattagttta tatgaaagat catttatcat ttgaagtcat tggtgaaaca cgagatgacg
    13981 cagtaggtga ggcttatgat aaagtggcac gaacaattgg tttaaattat ccaggtggtc
    14041 cacaagttga tcggttggct gctgaaggtg aagatactta ttcattccct cgtgtttggt
    14101 tggataaaga tagttatgat tttagtttta gtgggttgaa aagtgccgtg atcaatcaac
    14161 ttcacaatca acgacaaaaa aatattccaa tcattgaagc taacgtagca acgagctttc
    14221 aaaatagtgt tgtagaggtg cttacgttta aagctattca agcttgtaaa gaatatagtg
    14281 ttcagcgatt aattgttgct ggtggcgtgg cgagtaataa aggattacgt caatctttag
    14341 cggatcaatg caaagtcaat gacattcaat taactatccc aagtcctaaa ttatgcacag
    14401 ataatgctgc aatgataggc gttgccggcc actatttgta tcagcaaggt cgatttgctg
    14461 atttagcatt aaatgggcac agcaatatag atttagaaga gtattctgca gaataaaata
    14521 aacgtcagtt attaacatga ttacgatgaa cattattgaa actgttcata gtcttctgtc
    14581 atgtgatagc tgacgttttt atattgcaat taggggagtg agacagaaaa gataaagaac
    14641 cactaatgat ttattatgtt gggattctgc caacttgcac attattgtaa gctgactttc
    14701 cgccagcctc tgtattgggg cccccggact agtattgaaa aaacttatta caagcgtatt
    14761 ttcatttagt caaagactgt caatataaca atgttgcgac ttgaacattg attgatgttc
    14821 aagattcatg ctaaccattg gaaacattat cttttgctcg ttcatatatt tttgctggaa
    14881 atgaagtgat ttttaataat tcgatggcat tacgagtatt tgctttgcca ggcttaattt
    14941 tgtaatcaaa atgtatgtta ttattttcta ttacctcatt gaaatgataa ttttcataac
    15001 gttgttttaa gagttcagct aactcaatat catgtgttgc tgcaataact ctaaagttag
    15061 atttttcatg taaaaatgat agtactgatt ctgaagcggc aattcgttca gttgtgttgg
    15121 tacctttaaa aatttcatcg ataaagcagt atattttttg attatctgga atttcaacaa
    15181 tacgcttaat agattttaat tcagccataa aataactatc gcctgataac acatcatcgg
    15241 catttgccat tgacgtgaac acaattccag gttgatatac aaatttgctt gcggtaactg
    15301 tttgtatagc cgatgcaaga ataatgttta ttgctatgga tttcataaat gttgatttac
    15361 ccgaagcatt agacccagtt aacagtatat tttgtgaaag tgagaaatca ttggctactg
    15421 catctgctat gagtggatgt gttaactcag agaatactat gccatcattt gtatcatcaa
    15481 tttgtggttc agtataacat tctagcgttc tacgatacat tgctaatgca taatgattat
    15541 ctaattcagc tatgtaatcg aaacaatttt taagctcatt catatgtgtt gtatagcttt
    15601 tttgaattga atgaaataaa acataatcaa gcatgaaaat aagtttaact agtttaatta
    15661 ccatagctcc gatatcttca tcattaactt cagctaaaac actcgttaaa tgacgtgctg
    15721 ttctaaattg cttaaaattg acttcaggtt gtggagcatg tttaattttt gagatagtat
    15781 agccttgttt taaaacattg gatgcataaa agatagattt taagtcatcc tcatatgtac
    15841 gctttaaagt tgctgataaa atgatattaa ataggcaact cataagaaat aataaaatac
    15901 caacttgtga attaataaat ataactgcaa atgagataac tggtaaaaac gggcatagaa
    15961 acaatatatt ttgacgtttt accggtgtga tttggtctgg aaatgttgga taaacagttt
    16021 taccaatcaa agctaaatga tatgttacgt tttttctaaa ttcagcatta tcattaaata
    16081 aactaagtaa tgatttgttc gtaattgaaa gcattccacg taaacaggca tatagcttca
    16141 tttcaccaat agctgttaaa ttataattca tcttatgaaa aattgcattc atatttaagt
    16201 cggaccaagt tttatcatca actaatgaat gtgattcaaa tttttccttg tagagcttat
    16261 actcatagtc gaaatgtgag ttcggtctga taaaagcttc taatggagaa atcgtttgcc
    16321 ataatgtttc catagatttt aatagacgtt gacgactcat gtatcgtcca acaattccta
    16381 ttacagatgt aagtagaata attgctataa caaatattaa aaatgtttga tttgtgctca
    16441 taagtatctc cttatttatt tttaataata ataaaaatat acttcaataa tattattatt
    16501 tcataaagaa agtgtcttaa caatgaattt tgataaaaac aatgtcaata gagaacatgc
    16561 gtacttatca acaaagagtg aataacttgt ggataaaagg tgttgataac gtcatttatt
    16621 gtggatatca ggtgggaaaa cagaaaataa ataattgatt agtgttaatt tacttgtgga
    16681 taactaggat aagtctgtgg atagctataa tatcagcgtt tttattgtga ataaaaaaaa
    16741 ttaaaatttg taaaaaaata actctaacta tagcgaattt acagttagag ttatgtatat
    16801 ttttatagtt tttgttgtaa ttcttcccat ttagacatag cgtgttctaa tttttgttcg
    16861 ctatcttgtt tttggatagc taattcgttt gctttttgtg gattgttata cacttctggt
    16921 tgggttaatt gctcgtctat ttgtaagata gtagtctcta aagtttctat ttcattttca
    16981 cactcggata tttgtcgttc aagtttgcgt tgttcacgtc tttgttcttt ttggttatga
    17041 tacgacgatt gttccataga ctttttatgt gcttgtacgt taactgactg ttcttcttgg
    17101 tgcgctttca acgcttcggc ttcctcaact ttttcaatgt aatattgata atctcctaaa
    17161 tacatctttc cgccatcaat tgttaaatca aataccttgt ttgctaattg gttaataaag
    17221 taacgatcat gggaaacaaa tagtattgtt ccttcaaaat gttggagtgc ttgctctaac
    17281 atttcttttg aatctatatc gaggtggttg gtaggttcat ctaaaataag tacattgtca
    17341 cgttgcaaca taagtagtgc tagttgtaaa cgtgcttttt caccaccaga taaatcatta
    17401 attatctttt taacatcgtc ttgtacaaat aagaaacgtc caagaactgc tcgaatatct
    17461 ttttcattca ttaacggata ttgatcccac acataatcta aaatcgtttt actagattta
    17521 aattctgctt gcttttgatc ataataacca atttgtaaat ttgcgccgaa agtaatatcg
    17581 ccattaagcg ctttttgttg attagcaata gttttaatta aggtcgattt tccaatacca
    17641 tttggcccaa tgattgctat atgatcgcct ttagagacct ctatactgat aggtttggta
    17701 attgcagttt gataaccgat ttctaaattt tttacatgca tgacgtcatt acctgtattc
    17761 cggtcaaagc caaattgaat atttgcactt ttggcatcta acattggttt atcaatgcgt
    17821 tccatttttt ctaaaatctt acgtctactt tttgccattc cacttgttga agcacgggta
    17881 atatttttct caacaaaagt ttctaatcgt tttatttctg cttgttgact ttcatattct
    17941 tgcattcgtt tttgataata taaatcccgt tgctgtataa attcctcgta attaccaaca
    18001 tagcgtttga catcacctaa agccacatca taaatttgag taactatttt atctaaaaag
    18061 taacgatcat ggctgatgat gacgattgca cctttaaaat aacgtagata atcttcaagc
    18121 cactttgtcg tttctaaatc taagtggtta gtaggttcat ctaaaagtaa taaatcaggt
    18181 tcgtttaata gcatttgagc taaagataaa cgtgtttttt ggccgccgct aaaatcattg
    18241 ataggtttat tgaaatcttc ttcactaaaa tttaacccgt gaagtactgt tttaatttta
    18301 ctttcatatt gatatccttc taattgttca aattgattcg ataaagattc ataacgggac
    18361 atatgtgttt tatatgtatc actatcgtaa tcatttgcat gttttgataa ccaatctgtt
    18421 tcttctttga ttaagctttc cattcgttta atatgttcaa atggttttga catttcttca
    18481 aaaactgttg cattagaatt taaagtcatt tgttgagtta aataacctag ttttaagttt
    18541 ttaatttttg acacatttcc agaatcatag ttttctacac cagctataat tttcatcaat
    18601 gttgatttac cggcgccatt tcttcctacg ataccaattc gttcaccagt ttttacttca
    18661 aaatcaacat cagtaaatat atcttcacca tcgaacgatt ttgatatatg attgagttgt
    18721 aaaagtatca ttcgatcttc acctttcgtc tttctcaaat tttattaact tatgaaaaaa
    18781 gtcgtaatta ttacattaat aaccatttta cagtataaaa cgccgt
//
LOCUS       DAPDIM010000055        18228 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000055 DAPDIM010000000
VERSION     DAPDIM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 18228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18228
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.055"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(44..271)
                     /locus_tag="RFE25_002079"
     CDS             complement(44..271)
                     /locus_tag="RFE25_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817119.1"
                     /translation="MTKLTYPMLYITRKEKGDTQKKVASKLGISPQRYQLKESGKAIF
                     NLNECQILSEMYDMPIDELFSSKIKVEGSRQ"
     gene            complement(307..513)
                     /locus_tag="RFE25_002080"
     CDS             complement(307..513)
                     /locus_tag="RFE25_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817120.1"
                     /translation="MNNKVSNYRRYIGLTQNQMANNLKISVTAYRNKERGITPFKDSE
                     KVFIKNKLIENGIKDITIDDIFFN"
     gene            671..1318
                     /locus_tag="RFE25_002081"
     CDS             671..1318
                     /locus_tag="RFE25_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017636857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817121.1"
                     /translation="MSQQSILANNIKKIRKELGLTMEEFGEKFTHKAHKSIVSKWEKG
                     LTKPSNERLKEIAKLGNISVHQLIYGDFLGLLESIANEEIKFILDTNMCANNSFLANE
                     LSSSVSRFIFSYYERGKENFNENLFRKLLQHYLQLELDLGNRDLESLTYFAYQRTINA
                     QELVVDYYEDSKAKEFLKDESIDEFLTTISNKYFDLLEYIDDYRVKHDLEKISEE"
     gene            1324..2430
                     /locus_tag="RFE25_002082"
     CDS             1324..2430
                     /locus_tag="RFE25_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDU2817122.1"
                     /translation="MSYNLNLSHNIYKDAKLGTYYFRITYYDKSNTRKYITRKGFKQR
                     KDAVKKCNEMMDELEGVGHLNRLPFDKLVEEYIDWYSARRKTSSVKALKTHTNNHLLP
                     YFKSMDVFKMTTQDVMKFQNKKLKEGHSGDYLKKMHVYLVSLLNHAMKFHELKQNVAS
                     LVGNFEIESQKRLNYWTLEQFNQFYEALATQQQKLFFKLLFYSGARKGEIRALTWRDI
                     NFDDDFIHINKTDYHGEVTAPKTKSAIRDIYLPTHMMYDIKDYLIWYKENNIYKDDYV
                     LFGTFYKAYSESTIDRWFTNALKVLDEQLPNGQNFPRIVIHELRHSHASMLVNLGASV
                     MIIAQRLGHSDTTEVYNRYGHLYPSTQKEIVKYL"
     gene            complement(2541..2902)
                     /gene="ssrA"
                     /locus_tag="RFE25_002083"
     tmRNA           complement(2541..2902)
                     /gene="ssrA"
                     /locus_tag="RFE25_002083"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2993..3457)
                     /gene="smpB"
                     /locus_tag="RFE25_002084"
     CDS             complement(2993..3457)
                     /gene="smpB"
                     /locus_tag="RFE25_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDU2817123.1"
                     /translation="MAKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGS
                     ANLKDSYAQVKNGEMYLNNMHIAPYEEGNRFNHDPLRSRKLLLHKREIFKLGEQTREI
                     GYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVKRDVARDMKARY"
     gene            complement(3479..5851)
                     /gene="rnr"
                     /locus_tag="RFE25_002085"
     CDS             complement(3479..5851)
                     /gene="rnr"
                     /locus_tag="RFE25_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDU2817124.1"
                     /translation="MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLV
                     ELEQSGLIERTKTDRYQKKHSSKGHSKLIKGTLSQNKKGFAFLRPEDEDMEDIFIPPT
                     KINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDD
                     KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSI
                     IYQHGIEIEFPDEVLQEAEAVPDHIENTEIKGRHDLRDELTITIDGADAKDLDDAISV
                     KKLANGNTQLTVSIADVSYYVTEDSALDKEAYDRATSVYLVDRVIPMIPHRLSNGICS
                     LNPHVDRLTLSCRMEIDASGRVVKHEIFDSVIHSDYRMTYDAVNQIITEKDPNIREQY
                     KEITPMLDLAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEVGIPTDVQLRQRGEGERL
                     IESFMLIANETVAEHFSKLNVPFIYRVHEQPKSDRLRQFFDFITNFGIMIKGTGEDIH
                     PTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFTSPIRRY
                     PDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAE
                     YMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHIANMTDDYYRFEERQMALIGERQ
                     AKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDRSQRPARGKTIQAKTRGKSLD
                     KSKSDDKGRKKKGKQRKGKNQRNNDKSGNSKHKPFYKDKSVKKKARRKKK"
     gene            complement(5885..6625)
                     /locus_tag="RFE25_002086"
     CDS             complement(5885..6625)
                     /locus_tag="RFE25_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase"
                     /protein_id="HDU2817125.1"
                     /translation="MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYT
                     SYAPQYEGHAAPPEEILKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKL
                     SLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKNQETIDNEMDHFKPTET
                     LKELSEALDTIKDQVDEVFDPILVIQVENDNMIDPQSANYIYDHVDSDDKDIKWYSQS
                     GHVITIDKEKEQVFEDIYQFLESLDWSE"
     gene            complement(6741..6974)
                     /gene="secG"
                     /locus_tag="RFE25_002087"
     CDS             complement(6741..6974)
                     /gene="secG"
                     /locus_tag="RFE25_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDU2817126.1"
                     /translation="MHTFLIVLLIIDCIALITVVLLQEGKSSGLSGAISGGAEQLFGK
                     QKQRGVDLFLNRLTIILSILFFVLMICISYLGM"
     gene            complement(7041..7499)
                     /locus_tag="RFE25_002088"
     CDS             complement(7041..7499)
                     /locus_tag="RFE25_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817127.1"
                     /translation="MADRTNKEIKTGRFIATASIVFSILLIIHYFVSLDNATAKALLN
                     LTNQNTSDKAIDYILNSFRFTGIMYILAYLAGFITFWNRHTYVWWFMFAVYVSNSLFT
                     LINLSITIQAIKAAHGAYLTLPILIVIIGSVALAIYMLVVSIKRKSTFNR"
     gene            complement(7838..9142)
                     /gene="eno"
                     /locus_tag="RFE25_002089"
     CDS             complement(7838..9142)
                     /gene="eno"
                     /locus_tag="RFE25_002089"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDU2817128.1"
                     /translation="MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTG
                     EHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGT
                     PNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDA
                     PIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTE
                     DAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVD
                     YLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIEN
                     GIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK"
     gene            complement(9272..10789)
                     /locus_tag="RFE25_002090"
     CDS             complement(9272..10789)
                     /locus_tag="RFE25_002090"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDU2817129.1"
                     /translation="MAKKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQ
                     IEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIA
                     HVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSA
                     LKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKE
                     GVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGF
                     KVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHV
                     TYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILN
                     FANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDD
                     QPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH"
     gene            complement(10792..11553)
                     /locus_tag="RFE25_002091"
     CDS             complement(10792..11553)
                     /locus_tag="RFE25_002091"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDU2817130.1"
                     /translation="MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAI
                     QLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRE
                     LFHETDEEINKKAHAIFKHGMTPIICVGETEEERESGKANDVVGEQVKKAVAGLSEDQ
                     LKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKP
                     NNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK"
     gene            complement(11675..12865)
                     /locus_tag="RFE25_002092"
     CDS             complement(11675..12865)
                     /locus_tag="RFE25_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDU2817131.1"
                     /translation="MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTI
                     QYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEA
                     AIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHAS
                     NVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIAD
                     KIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSN
                     DAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTI
                     GVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKA
                     INNK"
     gene            complement(13004..14014)
                     /gene="gap"
                     /locus_tag="RFE25_002093"
     CDS             complement(13004..14014)
                     /gene="gap"
                     /locus_tag="RFE25_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDU2817132.1"
                     /translation="MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHL
                     LKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTD
                     KDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVA
                     KVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIG
                     KVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTED
                     EIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAEL
                     SK"
     gene            complement(14067..15080)
                     /locus_tag="RFE25_002094"
     CDS             complement(14067..15080)
                     /locus_tag="RFE25_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDU2817133.1"
                     /translation="MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHM
                     DMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIK
                     NKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAI
                     HLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLL
                     EPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQ
                     GQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKI
                     ILE"
     gene            complement(15781..16410)
                     /locus_tag="RFE25_002095"
     CDS             complement(15781..16410)
                     /locus_tag="RFE25_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4887 domain-containing protein"
                     /protein_id="HDU2817134.1"
                     /translation="MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFA
                     YVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQ
                     QNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQP
                     AQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK"
     gene            17113..18015
                     /locus_tag="RFE25_002096"
     CDS             17113..18015
                     /locus_tag="RFE25_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HDU2817135.1"
                     /translation="MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKIS
                     YVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSR
                     NKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVV
                     IGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESA
                     SGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPN
                     KIQALGFQFKYSNLKMALEDLIKE"
BASE COUNT         5675 a         3438 c         2746 g         6369 t
ORIGIN      
        1 attgttaaca atgaaactaa gcagatataa gttaagtaca ttttcattgc cttgacccct
       61 ctactttaat ttttgatgaa aataactcat caattggcat gtcatacatt tctgaaagaa
      121 tctgacactc atttaaatta aatattgctt taccactttc ctttaactgg tagcgttgtg
      181 gactaatacc aagtttgcta gcaactttct tttgcgtgtc acctttttct tttctagtaa
      241 tgtataacat tggataagtt agttttgtca ttctaatcac tcctaaagga aactttatgc
      301 tacttattaa ttaaaaaaaa tatcatcaat agtaatgtct ttgataccat tttctattaa
      361 tttatttttt ataaacacct tctctgaatc tttaaatggt gttattcctc tttctttatt
      421 tctataagca gtaactgaaa tttttaaatt attagccatt tgattttgtg ttaaaccaat
      481 ataccttctg taattgctta ctttattatt catcaaaacc acctccttga aactttatgc
      541 tacaatcata taacctctcc ttttacttgt caacactttt tatgatactt tatgaaactt
      601 ataattccac taaagctaaa ttaatgatag aatactaaca taaatattca tcattaagga
      661 ggcgtttagt atttcacaac aatcaatttt agctaataat ataaaaaaaa ttagaaaaga
      721 attaggtctt acgatggaag agtttggtga aaaattcaca cataaagctc ataaatctat
      781 tgtttcaaaa tgggaaaaag ggctaacaaa accaagtaat gaaagattaa aagagattgc
      841 taagttaggg aatataagtg tacatcaatt aatatacggt gattttctag ggttgttaga
      901 aagtattgca aacgaggaaa taaagtttat tttagacaca aatatgtgtg ctaacaatag
      961 ttttctagct aatgaattat catcttcagt ttctcgtttt atattttcct attatgaaag
     1021 aggtaaagaa aattttaacg aaaatttatt tagaaaattg ttacaacatt atttacaatt
     1081 agaattagat ttaggaaata gagatcttga atctttaaca tatttcgctt atcaaagaac
     1141 aataaatgcg caagaattag tagttgacta ttatgaagat tcaaaagcaa aagaattttt
     1201 aaaagatgag agcatcgatg aattccttac gacaatatct aacaaatact ttgatctatt
     1261 agaatacatt gatgactata gagttaaaca tgatctagag aaaattagtg aagagtgaat
     1321 acaatgtcat ataacttaaa cttatcccac aacatatata aagacgctaa acttggcact
     1381 tactatttcc gtatcactta ctatgacaaa agcaatactc gtaagtacat aacacgtaag
     1441 gggtttaaac aacgtaaaga tgcagtaaag aaatgtaacg aaatgatgga cgaattagag
     1501 ggagtcggac accttaatag attacctttt gacaagctcg ttgaagaata tatagactgg
     1561 tattcagcac gtcgaaagac atcaagtgta aaagcattaa agacacatac caataaccat
     1621 ttgctacctt attttaaatc tatggatgta tttaaaatga ctacacaaga tgtgatgaag
     1681 tttcagaata agaaattaaa agagggacat tctggagact acttaaagaa gatgcatgta
     1741 tatttagtat cattactgaa tcatgcaatg aagtttcatg agttaaaaca aaatgttgca
     1801 tctcttgtag ggaattttga aatagaatca cagaaacgat tgaattattg gacgttagaa
     1861 caattcaatc aattctatga ggcgcttgct acacaacaac aaaaattatt tttcaaacta
     1921 ttgttctact ctggagcaag aaagggcgaa attagagctc tcacatggcg cgatattaac
     1981 tttgatgatg actttatcca tataaacaaa acagactatc acggtgaagt gacagcccct
     2041 aaaacgaaat cagccatacg tgatatatat ttacctactc acatgatgta tgacatcaaa
     2101 gattatttaa tttggtataa agagaataac atatacaagg acgactatgt attgtttggc
     2161 acattctata aagcttacag cgagtctact attgatcgtt ggtttactaa cgcattaaaa
     2221 gtgttggatg agcaattacc aaacggacaa aatttcccta gaatcgttat acacgagtta
     2281 agacatagcc atgcatctat gctagttaat ctaggggcta gtgtaatgat tatagctcag
     2341 cgtttaggtc acagcgatac gactgaagta tataaccgat atggtcattt atatcctagt
     2401 acacagaaag aaatagttaa atacttataa ggcactgcca actaaaattg gttgtgtctt
     2461 tttgtatcct gtgcactatc tgtgcacttt ttgtgcactc aaaaataaaa agcctacaac
     2521 cactaaggtc gcagactata taatggagac ggcgggattt gaacccgcgt ccagaggtcc
     2581 tgatacacat ctttctacgt gtgtagttta tcgaaaggtt tcgcatcatg aaaagtgata
     2641 aacaaccaac atgatgctag cttgattaag tttcttctaa acagacttca aacggcagtg
     2701 tttagcatat cctattaagg ttgaatcgcg ttaacagcac ataggaaatg ctgttaggcg
     2761 atgcagagtg cgattaggca gctactgcga aattattgtt tgatttgcca gttattataa
     2821 actgtgtgtg ttgatgacga agccaaccct ccgacacgct taatgagctc gggggacccc
     2881 tgtcgaatcc atgaacgtcc ccgaaataat aaatcaaaca aatcatactt ttgtaattta
     2941 caaaagcaca tataactata tcaaatatag cccgattaag caactaaatc gcttaataac
     3001 gggctttcat atcgcgcgca acatctcgtt tgactgcttt ttctttcaaa gcttgacgtt
     3061 tatcatattt tttcttacct cgtgcaacac caagtaatac tttacaatgt ccatgcttca
     3121 aataaagctt taacggcaca atcgaataac caatttctcg agtttgttca cctaatttaa
     3181 agatttcacg tttatgcaat aataattttc gagaacgaag aggatcgtga ttaaaacgat
     3241 tcccttcttc gtatggtgct atatgcatat tattcaaata catttcaccg tttttaactt
     3301 gcgcgtaact atctttaagg ttagcactac ctcggcgaat cgattttatt tctgtacctt
     3361 gtaatacgat tcccgcttca atcgtatctt caatattata atcatgtctt gctttacgat
     3421 tttccgctaa tgtacctggt gatttcttct tagccattca tactcacctc attgctgctt
     3481 attttttctt acgacgtgct ttctttttca cacttttatc tttataaaat ggcttatgct
     3541 tactattacc tgatttatca ttattacgtt ggtttttacc tttacgttgc ttaccttttt
     3601 tcttacgacc cttatcatca gatttcgatt tatctaaaga tttgccacgc gttttagctt
     3661 gaatcgtttt acctcttgct ggtcgctgtg agcggtcatt tttaggtaaa ggcattccaa
     3721 caatttgaaa atcaattaat cgttcatcta catcaacatg cgtcacttta accttaactg
     3781 tgtcaccaat tctaaatact ttagcttgac gctcaccaat taatgccatt tgacgctctt
     3841 caaaacggta ataatcatca gtcatattcg caatatgaac cataccttct atcgtatttg
     3901 gcaattcaat gaacataccg aagttagcta ctgagctgac aataccttca aattcatcac
     3961 caatatgttg aatcatatat tctgcttttt tcaattcatc agtatcacgt tctgcctcaa
     4021 tagcacgacg ttcacgttta gaagtatgtt cagctaactc aggcaatttg tcttcccaac
     4081 gcttcacttc tttgttatcc attgatttct caattaaata cttacggatt aaacgatgaa
     4141 ctgttaaatc aggataacgt ctaattggtg atgtaaaatg cgtataatat tcagctgata
     4201 agccaaaatg tcccaagttc acatcatcat aatgcgcttg ttgcattgaa cgtaacatca
     4261 ttgttgaaat gaccatttgt tcaggtcgac cttctacttc ttcttgaacc ttttgaagtg
     4321 ttgttggatg aatatcttcg ccagtgccct taatcatgat gccaaagttt gtaataaaat
     4381 caaagaattg tcttaagcga tctgatttag gttgctcatg cactcggtaa ataaaaggta
     4441 catttaactt actaaaatgt tcagcaactg tttcatttgc aattaacata aatgattcaa
     4501 ttagacgttc accctcgcca cgttgtctta attgaacatc tgttggtata ccgacttcgt
     4561 taactaatac ttttgcttca ctaatatcaa aatcgatttc accacgtcgt tttctcattt
     4621 gaatcaaacg attagataaa tcttgtgcta aatctaacat aggcgtaatt tctttatatt
     4681 gttcgcgaat gttaggatcc ttttcagtaa taatctgatt taccgcatca tacgtcattc
     4741 gataatcaga atgtataaca ctatcaaaaa tttcatgttt aacaacgcga ccactagcat
     4801 cgatttccat gcgacagctt aacgttaaac gatcaacatg aggatttaat gaacaaatac
     4861 cattgcttaa tcgatgtgga atcatcggaa tcacacggtc aacaagatat acacttgtcg
     4921 ctctatcata agcttcttta tctaaagctg aatcttcagt tacataataa ctgacatcag
     4981 caatacttac agtcaactgc gtattaccgt tcgctaactt tttaacacta attgcgtcat
     5041 ctaagtcttt agcatcagca ccatcaattg tgattgtcaa ttcatcacgt aaatcatgac
     5101 ggcctttaat ttcagtattt tcaatatgat caggtactgc ttcagcttct tgtaacactt
     5161 catcaggaaa ttcaatttct atgccatgtt gatagataat agataaaata tctacgccag
     5221 gatcattttt atgtcctaaa atagcagaaa tatgtccttc tggattatct gaaccatcag
     5281 catatttagt aatttgaaca agtaccttat gcccatctac tgcacctaaa ctttgtcctt
     5341 taggaatgaa aatatcttgc ataatacgtt tatcatctgg aataacaaat ccgaaatgtc
     5401 tagcttcact atacgtacca acaacttgag ttactgaatg cttctcaatc gacttaactt
     5461 ccccttcaat tttaccttta tgttcacctt tagattgatg tatttctaca attacagtat
     5521 ctccatctaa ggcacgatta atttttgttg ggggaataaa tatatcttcc atatcctcat
     5581 cttcaggtct taagaatgca aagccttttt tattttgact taacgttccc tttatcaatt
     5641 ttgaatgacc ttttgaacta tgcttttttt gatatctgtc tgtttttgta cgttcaatta
     5701 atcctgattg ttctaattct acgagcacct taattaaatc tctaaatgag tcggcactac
     5761 ttaaacctaa tgcatcttga aaatctgaca ctgacatagg ttcatattca ggttgattaa
     5821 taatctcttc tattgattgc tttaaattca ttatgcccct cctttctaat gttaaaatct
     5881 ctttttattc tgaccagtct aatgactcta aaaattgata aatatcttca aatacttgtt
     5941 ctttttcttt atcaatcgta ataacatgtc ctgattgact ataccacttg atgtctttgt
     6001 catcagaatc tacatggtca tatatataat ttgcggattg tggatcaatc atattgtcgt
     6061 tttctacttg aatcactaaa attgggtcaa atacctcatc aacttgatct ttaatcgtat
     6121 ctaatgcttc acttagttct tttaaagttt cagttggttt aaaatgatcc atttcattat
     6181 caatagtctc ttgattttta ccttcatact ttttaaaatt acgtgcatac tctaaaaagc
     6241 cttcataaat ggcaccttca gttttgccac ccattggtgc acacatcgtt acaataccct
     6301 ttacatctct atttaagctt aattttaaag caaaatcccc acctaatgat agaccagcaa
     6361 caacaatttc atcataacct tgttcaacaa gataatcata accatctaac gcatctttaa
     6421 accaaacgaa aggactagat ttcagtattt cctctggtgg tgccgcgtga ccttcatatt
     6481 gtggtgcata cgaagtatat cccttttttt gtaaaaatcg acctaattga cgtacatcag
     6541 acgaattgcc tgtaaatcca tgtaataata acacggcacg tttgccttct tcaaaaaaga
     6601 aaggttttgg taattttatc tgcataaatc taacgctccc tttgcatact taactaggct
     6661 atatatttta catagcttat tgttaatcta ttacattctt aattataaat aaaaaagccc
     6721 gacatttaca tcgccggacc ttacatacca agataactta tgcaaatcat aagtacaaaa
     6781 aataatattg ataaaataat tgttaatcta tttaagaata aatcgacgcc acgttgtttt
     6841 tgtttaccga ataactgctc agcaccacca ctgatggcac ctgaaagtcc actgctttta
     6901 ccttcttgga gtagtacaac agttattaat gcaatacaat caatgattaa taatacgatt
     6961 aaaaatgtat gcataaattg tcctccgttc cttatatacg acaagtagta tatcatattt
     7021 ttattgttaa aatcaatttt ctagcgatta aatgtacttt tacgtttgat agaaacaaca
     7081 agcatataaa tcgctaatgc aaccgaacct ataataacga ttaaaattgg caatgttaag
     7141 tacgcaccgt gtgcagcttt tattgcttga attgtgattg ataaattaat caacgtaaac
     7201 aaactatttg atacataaac tgcaaacata aaccaccaca cataagtatg tcgattccaa
     7261 aaagtgatga agcctgctag ataagccaaa atatacataa taccagtgaa tctaaagctg
     7321 tttaaaatgt aatcaatcgc tttatctgaa gtgttttgat tcgttaaatt aagtaatgct
     7381 ttggcagtcg cattatccaa cgaaacaaag taatgaataa tcaataatat tgagaatacg
     7441 attgatgcag ttgcaataaa gcgtcctgtt ttaatttctt tattcgttct atcagccatt
     7501 tgtttactcc tcatatattt aaatacgttc tataaaacct ttatttaatt ttacctttca
     7561 ataaaagtga ataccctgtc atacaatatt catttcaaca taaatttatt ataccagttt
     7621 aagaatacaa gttaaatatg tgttattagt tacctcatga ttattagtct gttatgaata
     7681 atacttcaaa ataaaaaacc taccacagtc tcaactctgt ggcaggttat aaatacaagc
     7741 gtgaactttt taagcgtgaa ctcaaaaact ttattcaatt tataccgaca taataatcct
     7801 caactaaaat tatggcagta cttaatgttt aaaatgatta tttatctaag ttatagaatg
     7861 atttgatacc gtcatattta gcagtttcaa ataattcatc ttcgatacgt aataattgat
     7921 tgtatttagc aatacggtca gtacgtgata atgaaccagt tttaatttga ccagcgtttg
     7981 tagcaacagc aatatcagca attgttgtat cttctgtttc acctgaacgg tgagaaacta
     8041 ctgctgtgta accagctttt tgagccattt cgattgcatc aaatgtttca gttaatgtac
     8101 cgatttggtt aactttaatt aagattgagt taccaattcc gttttcaata ccttttgcta
     8161 aaatttcagt gtttgttacg aataaatcgt cacctactaa ttgtacacgg tcaccgatac
     8221 gttctgtaag ttgtttccaa ccatcccagt cgttttcgtc cataccgtct tcaattgtaa
     8281 tgataggata tttgtctact aattgttcta agtagtcaac ttgttctgca gctgtacgtt
     8341 ttgcaccgtg ttcgccttcg aacttactgt agtcatatac accattttca tagaattctg
     8401 atgatgcaca gtcaaatcct aagaatactt cttcacctgg tttgtaacca gctgcttcga
     8461 ttgcttggat aattgtttca acagcatctt cagtaccttc aaatttagga gcgaaaccac
     8521 cttcgtcacc tactgcagtt tctaaaccac gtttgcttaa aattgatttt aagttgtgga
     8581 aaatttcagt accccaacgt aatgattctt tgaacgttgt agcacctaca ggtaaaatca
     8641 tgaattcttg gaatgcaatt ggagcatctg agtgagaacc accattaacg atgttcatca
     8701 ttggtactgg taactgctta ccattaaatc cacctaaata tttgtaaagt ggttgaccta
     8761 ataagtcagc tgctgcacgt gctactgcga tagatacacc taaaatagca tttgcaccta
     8821 atttaccttt gtttggagta ccgtctaatg cgatcatcat tttatcaata gatacttgat
     8881 ctaatactga aaattcacct tcaataattt ctggtgcgat gatttcatta acgttttcaa
     8941 ctgctttagt aacaccttta cctaaataac gtgatttgtc tccatcacgt aattcaacag
     9001 cttcgtgttc accagttgaa gcacctgatg gtactaatgc acgaccaaat gcgccacttt
     9061 cagttaatac ttctacttca acagttgggt taccacgaga gtctaagact tcgcgagcgt
     9121 aaacatctgt aataattggc atgtttataa tctcctttaa atagttattc tataattatt
     9181 atagctttat tctttcattt aacaaaatga tattactatt attttcaaaa aataagtgtc
     9241 attaagcgtt tacttaacat cttttacaat attagtgttt aattaaagat tcacctgtca
     9301 tgtcttcagg ttgttctaca tttaataaat ctaataatgt aggtgctaag tcacctaagc
     9361 gaccagtttc tcgaagtgta acgccttctt ttgttacaat cactggtact gggttcgttg
     9421 tatgcgtagt cattggttga tcatcatccg tcaatacttg atcagagtta ccatggtcag
     9481 cagtaataat tgcataaccg tccatgtcta aaatcttatc aacgacttca cctaaacatt
     9541 catcaaccgc ttcgattgct ttgattgtcg gctcaagcat accactatgt ccaaccatat
     9601 cagggttagc aaagtttaaa ataattaagt ccaagtcacc tttatttaac tcttctaata
     9661 atgcatcttt aacttcataa gcactcattt ctggtttcaa gtcatacgtt gcaactttag
     9721 gtgaatcaat taaacgacgg cgttcacctt taaattcctc gttacgtcca ccactcataa
     9781 agtaagtaac gtgaggatat ttttcagttt ctgcaatacg taattgtgtt aaattgttat
     9841 tttgtgcaat ttcaccaatt gtattattta aatcaacttt ttcgaaaacg atagccgcat
     9901 cgatattgtc gttatactta gtgaatgttg catagaataa gtctttaact tgttcaactt
     9961 taaagccttc gaatgctctg ttcgcaaaaa tttccgataa ttgtgctgct ctatcaggtc
    10021 ggaaattata gaagatcact gcatctccat cattaacacc gtcattttga ttctcaacga
    10081 tgaatggtac tacgaattcg tcagttaagc cctcattata gcttgcttct acaccttctt
    10141 tggcagttgc ataagttggg gcatcaaaat tacgaatagc attgtaagct ttttcttcac
    10201 gttcccaacg tttgtcacgg tccattgcat aataacgacc agacacagat gcaaattgac
    10261 caatgcctaa ttcattgaat ttagcttcag tctcttcgat gtatttcaaa gcggattttt
    10321 gatctacgtc acgaccatct aaaaatgcgt gtacgtaaac tttttcaaca ccttgttttt
    10381 tagcaagttc taacaaagca aataaatgtt tgtaatgact gtgcacacca ccgtcagaca
    10441 ataaaccaaa gatgtgtaac gctgaatcat gtgaattcac gtgtgcaatt gcattattta
    10501 aaacatcatt ttcaaagaaa tcaccgtctt caattgattt attgattcga gttaaacttt
    10561 gataaacgat acgtcctgca ccgatattca tatgaccaac ttctgagtta cccatttgtc
    10621 cttcaggtag tccaacatct aagccactcg cttcgatttg agtcgttgga tatttgttgt
    10681 aataacgatc aaaattaggc ttgtttgcta attttaccgc attaccatgt tcgctttcgc
    10741 ggttcgcaaa accatctaaa ataattaacg cagttggttt cttagccatg attattttgc
    10801 accttctaac aattgtacga aatcttcaac tttaagtgat gcgccaccta ctaatgcccc
    10861 atcaatatca gtttgtgcca tgtattcttt aatgttgtta ggtttaacac taccaccata
    10921 ttgaatacga gttgcttctg atacttcttt gcttgataag tcagcaatag tttgacgtac
    10981 aaatgcacac atttcatttg catcttcaga tgttgatgat ttaccagttc cgattgccca
    11041 gattggctca taagcaatta caactgattt aagttgatct tcagataaac ctgcaacagc
    11101 tttcttaact tgctcaccta caacatcgtt agctttacca ctttcacgct cttcttctgt
    11161 ttcaccaaca caaataattg gagtcattcc atgtttgaaa atagcgtgcg cttttttgtt
    11221 aatttcttca tctgtttcgt ggaataattc acgacgttca gaatgaccga taacaacgta
    11281 tttaacgcct aaatctgcta atgcaactgg agacgtttca cctgtgaacg caccattatc
    11341 ttcgaaatac gtattttgag caccgatttc taaaccttgt gcttttcctt ctttaactgc
    11401 agtagttaat gcatctaatt gaattgctgg tgcacaaatt actgattcta cttcttttga
    11461 atctggtaat gttggtaatg cattgacgaa gtcttttgct tcttgtactg ttttgttcat
    11521 tttccagtta ccagctataa ttggtgttct cattaaagac actccttgtt ttgtaaatat
    11581 ttttgaaaag tgatgaaaca cgatgtcatc ttgtgactgt tttcccgtaa caatgttaaa
    11641 caaacatgcc acatcacttt aaactatcac tttattattt attattgatt gctttgatac
    11701 caggcaattc tttaccttct aggtactcta atgacgcgcc gccaccagtt gaaatatgag
    11761 tgaagtcatt ttcaaaacct aaagagattg ctgctgcagc tgaatcaccg ccaccgataa
    11821 tcgtaattgc atctttaagg tttgcaattg ctttacatac accaattgta ccttgtgcaa
    11881 agttactgaa ctcgaataca cccataggtc cattccatac aacagtgtgc gcaccttcta
    11941 attcatctgc aaataatttt acagtgtttg gtccaatatc cataccttct tggtctgctg
    12001 gaattgaatc agatggtact acagtgattt tggcatcatt agaaaattct ttagcaactt
    12061 tagtgtctac tggtaataca attttatcac catgtttttc taataaatct tttgcgaagt
    12121 cgattttatc ttcttctaat aatgaaatac caatttcttt accttgcgct tttaagaaag
    12181 tataagccat acctccgccg atgataattt tatcagctat gttaactaag tttttgatga
    12241 cattaatttt gtcagatact tttgctccac ctaaaatagc aacaactggt ttatgtggat
    12301 cgttaactac gccaccaata aacttaattt ctttatccat taagaatcca gctgcagttt
    12361 ctaaatgtgt agaaatacca acattagatg catgctcacg atgcgcagta ccaaaagcat
    12421 catttacaaa cacatcacct aaagatgccc agtatttacc taattctgga tcatttttag
    12481 attctttttt accgtctaaa tcttcataac gtgtattttc aactaataat acgtcgcctt
    12541 ctttaaggtc tttaatagca gcttcaagtt tttcgccgcg tgtttctggt acgaaaacaa
    12601 cttctttatc taatttctta gataagtctt cagcaactgg acgtaaagtt aattttgctt
    12661 tatcactttc ttctttcact ttacctaaat gtgaaaatag tacgatttta ccaccttgtt
    12721 cgatgatgta ttgaattgta ggtaaagctt gaacgatacg gttgtcatta gtaatttcac
    12781 cgtcttttaa aggtacgtta aaatcagcac gtactaggac tgttttacct ttaagatcta
    12841 aatcagaaac aattttttta gccatggtgt ttcctccttg taattaggaa attttatata
    12901 aaaataagcg gagaagcgtt tgtgctcccc gcttactcat aagctttaat taatgctaaa
    12961 tagttctgag cactagcgta tttgaataaa aactatacta aaattattta gaaagttcag
    13021 ctaagtatgc taatgtacga actaattgtg cagtatatga catttcgtta tcataccaag
    13081 ctgcaacttt aactaattga cggtcgccaa ctgacattac acgagtttgt gtagcgtcga
    13141 ataatgaacc gtaagtcata cctacaacgt ctgaagaaac gatttcgtct tcagtgtaac
    13201 cgaatgattc gtttgaagca tttttcatag cttcgttaac ttgttcaact gttacgtctt
    13261 gtttttctaa tactactgtt aattcagtta atgaacctgt agctacagga acacgttgtg
    13321 caccaccatc taatttacca tcgatttcag gaataacttt accgatagct ttagcagcac
    13381 ctgttgagtt agggatgatg ttttctgccg ctgcacgagc acgacgtttg tcaccttttc
    13441 tgtgaggtgc gtcttgtgta ttttgatcac ctgtgtaagc gtgaattgta gtcattaaac
    13501 cttcaactaa accaaagtca tcgtttaaaa ctttagcaac tggtgctaat gagtttgtag
    13561 tacatgaagc acctgaaaca actgtttcag aaccgtctaa ctcttggtgg ttagtgttga
    13621 atacgattgt ttttaagtca ccagtagctg gtgctgagat taatactttt ttagcgcctg
    13681 cttcaatatg agcttgtgct ttatctttat cagtgtagaa accagtacat tctaacacta
    13741 catcgatatt taagtctttc caaggtaatt tgcttgcatc tggttcactg aatgatttaa
    13801 cttctttacc atttacgcgg aaaccaccat caactacctc tacttcacct gtgaaacgac
    13861 cttgcatagt gtcatatttt aataaatgcg ctaacatgtc gtcatctgtt aagtcgttta
    13921 ctgctacaac ttcaagacct tctacttctt gaattcttct gaatgctaaa cgaccaattc
    13981 taccaaaacc attaattgct acttttactg ccattataat ggcctccttt aaaatgatat
    14041 ttaaaaagta ttaaactttt tatctcttat tcaagtatta tctttgctgc ggcttcatca
    14101 gtgattaaca ctgtattctt gggtgcaatc gtcaagtatg ctttaattgc ttcacctttc
    14161 gatttgcctc ctgcaactgc aaaaataaag tcttttgatt caaggtcttc taattgaagt
    14221 ccaattgttt taaccttatg gacaatttga ccttgtgtat caaaataata accaaatgcc
    14281 tctccgacag cttgatgatg ttgaagttgt tcaatgacct tttcaggtga ttgacgtcga
    14341 tgcgccatct tcagcgcatc accaatgccg tgtaatataa cgtttgcttg tttaattttg
    14401 tctaaagtgt ttatgactga tggctctaac aacaatgtgt tatatgttgt ttcactgaca
    14461 ttatcaggta catacatcgt cgtataataa ccgccagctt gttgtgccat actggctgca
    14521 attgtgtttg cctgaaagac aacattttcg cctagtccac ctctggctgg tacgaagaat
    14581 acattatatg gtaataaatg aattgcttca ctaacacatg ccatcgtgga tccgccagtt
    14641 acagcaacta tcgcgtcttc ttgtaatatg ccttcaagta attgacctgc ttgtctacct
    14701 aattctgttt taacagattg actattatca gcatcaccag gaacaacatg aacttcctta
    14761 atttgaaatt tattcttaat accttctgac agacgattat catctgcata gatatcaaag
    14821 taacctttca attgcgaaat cagttgctca ccttcagctg taatttccat tccggtaggc
    14881 ttaactttta tcaaatcttg tttcttaagc atatctgttt cagaacgcag tacacgttca
    14941 gtcatatcca tatgttcgct taaacttcga cgtccgacag gctgattttt tgagatagta
    15001 gtaagaatag aaaaacgttt atacatttta tctatgagat ccggtataag cttttgctgt
    15061 gcttgcaata agtctttcac tactacctcc tccttatatt tataaatgta aataaggata
    15121 tgtcacaacc agtggttgcc tttttaagtc ccgcgtggga caaaaattaa cctctttaca
    15181 cttgcaatag tactattcta tttcaaaaat tgcaagcata aaacttaaat tttctaaata
    15241 atttgataaa gcgcttgcaa tacattttcg atttgttatt caacaaaacg ttttatttta
    15301 ttcgctgtag tcaaatgtat acccttatac tgactcgcta atcatttgct tattatttga
    15361 gactaagaca taaaacaatg ctctagaatc cgaaaagtca cattagtagt agttgaccga
    15421 acgaaaatgc acttgtaaca agctttttcc aattaaagtc aggggcccca acatagagaa
    15481 attggatttc caatttctac aggcaatgca agttggggtg gggccccaac acagaagctg
    15541 acggaaagtc agcttacaat aatgtggaag ttggggtcag acgacgaaat aaattttgcg
    15601 aaaatatcat ttctgtccca cctcactcaa aataaatttc actatccgta aaataaacaa
    15661 ctaactattt aagtatcatc tctcccctaa ttaacaatta taaaaataag aaccaatatt
    15721 cgagacaacc taattaattg tgttgtctgt catactggtt catttttgtt tgactaaata
    15781 ctacttatca ttagcattat tttgtttatt tgttgttgat tggctatttt gttgtggtgc
    15841 ttgtggtttt gcttgctgat ttgattgatt attttgttga ttattatttg gctttggtgt
    15901 tggttgttgc ggctgtggtt taggctgagc tggttgttta ttatcatcag ttttcttctg
    15961 attatcatct gatttatctt gagatgcatt gtcatcctta tctttcgact catcctttga
    16021 tgctttatca tcattctctt ctttagcagg acgttgcttt gtaggtgctt gttgctgagg
    16081 tggcacatat tgatattgat tctgctgtgg caattgctga tattggtttg cttgtgaatc
    16141 tagctcattc tgctcttttt cctcttgttg ctttttcttt ctctcttttt ctgcattttc
    16201 tttttgacgc ttttcttttt gttcctgctt ttgttcgttc aacatacgtt ctttagcttt
    16261 attcgaatga tctacatatg caaaaattgc aaatactaat cctccgagta atagcaatac
    16321 cgtcgcaatg ctaactactt tcgctgttgt actcattttc ttcttacttc catcttcatt
    16381 tttattgtag tcgtaatttt gattcgacat actctccctc acttcaaact aatttaaata
    16441 tagaaattat cacgcaacca ttaacatttt cacaactaat ttgcttacct agtttctaca
    16501 aatattaata aacatttact ctttttgcct tcttcaactt aaaactgcct tcactattac
    16561 tcactcgtaa atcggattca tttttacaaa gaaatagtag tcttatatat cttaacattt
    16621 aataactaaa tcaaacatat tttgagcctt tttttgaaaa ttaacatttt aacctttttg
    16681 attttacaac aaattatagc tacgtattga aaattaaagc attggtttaa gtgttgtgtt
    16741 aaaagttttt atgtttagat tgttatatta ctatgtattc ttaaatttgt ttaaaaaatt
    16801 aatgctttaa attgatgtat aatgggaata agaaataaat aaaaacgacc cgcacgatta
    16861 acgtacgggt ccactactaa agggagtcaa atttttacct tcgtttgtat catgcagcgt
    16921 tttacacata cttttaagag atgtttattc gttatcgaag gtacaccttt attataactt
    16981 atatcatttt tattaaaata caattcaaaa aaagttattg acatattatt gtctaaataa
    17041 tgtataacct ttgaacaaca ataatgatta ttaaatagta actaaataca aaattacatg
    17101 gggtgaatga taatgaaaca atacttaatt actggtggga ctggtatggt tggatctcaa
    17161 ttagttaatg aaattaaaaa atcagattca catatcacga tattaacgcg acacgaccaa
    17221 atttcaaatg ataagaaaat ttcatatgtc aactgggcta aatctgggtg ggaacacaaa
    17281 gttcctcaaa atatcgatgt ggtcatcaac ttagcaggtg ctacactgaa taaacgatgg
    17341 acaccggaat ataaacaaac gctaatgcta agtagaattc aatctacgca agctttatat
    17401 gaattgttta aatcacgtaa taaagcacct aaagttttat ttaatgctag cgccactggt
    17461 tactatcctc ctgatttatt tatgagttac acagaagttt ataaaacttt accatttgat
    17521 ttcttatcag atattgtgta tcaatgggaa cgtttcgcac aacaatttga acaattaggt
    17581 acgcgagttg tcatcggtcg tttcggtatg attttatcga atgaaggcgg tgcgttacaa
    17641 acaatgaaac taccatacaa atattacatt ggtggtaaat taggttctgg tcaacaatgg
    17701 tattcatgga ttcatatcaa tgatttaatt caagctattt tatttttaat aaataacgag
    17761 tcagctagtg gtccgtttaa tttaactgca cctatacctg agcgtcaaaa tttatttggc
    17821 tacactttag caagagctat gcataagccc catgaaactt gggcaccaag tcttgcaatg
    17881 cgtctcatac ttggtcaaat gtcaacagta gtattggata ctcaaaaagt attacctaat
    17941 aaaattcaag cattgggatt ccaatttaaa tatagtaatt taaaaatggc acttgaagat
    18001 ttaatcaaag aataatcaat accattaatg agcattagaa acaacatatg tactaaatgt
    18061 aatgtctaga gcgacttaca aacaaaggat tgaaatgttc ctttcaatgt ctactttgaa
    18121 gggaacattt catatagtta cggttcaact agcttcattc aatcatattt ccgctcaaag
    18181 tatagtaaac aatttattga cacctcggtt tactcataca aaaagagc
//
LOCUS       DAPDIM010000056        17887 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000056 DAPDIM010000000
VERSION     DAPDIM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 17887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17887
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.056"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            284..1774
                     /locus_tag="RFE25_002097"
     CDS             284..1774
                     /locus_tag="RFE25_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDU2817136.1"
                     /translation="MNYFVGNSLGVNLTGIEKAIINRLNLFKEMGRPAQCVFLSWNRY
                     LYRNAQNYITSSDYINMYDFFQEATYLERNEPFDWLSYWTDECHYTLKHVENSHDFRI
                     YDQERFLMYAHFQDPKYRILDYVNHFDSQRRKVKRDFYDVRGFLSCSRILVDKQQTLC
                     EFFYNPEGDTKLEKYFSYKDGKPEVQKIIVYYANKQYFFNNETELGAFFIKQLYQHGD
                     LFFSDRNVYTAPIFNLTPESIPVVAVLHSTHIKNIDALDSSPFKNVYKAMFENLSRYR
                     AIIVSTEQQKLDVEKRINHTIPIVNIPVGYSETIDTPVQTLDQRSVKLISVARYSPEK
                     QLHQQIELIKRLVSYVPKIELHMYGFGSESKKLNELIQKYGLENHVYLRGFLSNLNQE
                     YSDAYLSLITSNMEGFSLALLESLAHGVPVISYDIKYGPNELITPDFNGYLITKNDED
                     ALFDKVKYVIDHPEVQQRLSKGSLAKAQQYSKASLIKQWDQFVRLI"
     gene            complement(1899..3371)
                     /locus_tag="RFE25_002098"
     CDS             complement(1899..3371)
                     /locus_tag="RFE25_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDU2817137.1"
                     /translation="MNYILGTILESKITGVEKAQINRLKLFKQHGISSKCVYVKWNPY
                     SYTYAKQHQIENDVFTMYDYFQKAINYKKTKQVNWIQYWEKSCRYTLKFVENSNDVRI
                     YDEEQFVMYAHFLDKQYHQLNYVNYFDHKRRKVKRELYDGRGFLSCSRILGEGQRIVL
                     ENYYTPNGEIVIQKYFDDIKGKNTLTKVILNEDQQQQFFDTEDELVQYFLHQLCKNND
                     QIILDRPHELGNVIAGLNQSIPVVVVLHSTHLSGTGNGIKSFYKTVFNNLTRYKAIVV
                     STEQQCQDISQYIENKIPVINIPVGYVANLKYQFDINQKEKNHIISIARLVENKQIKH
                     QIEVIKQLVTKHPNIQLNIYGHGNGLSEYRQLVEDYHLSEHVKFHGFKTHINEEIAKA
                     ELMLSTSKMEGFGLAILESLSVGTPVISYDIDYGPSELIQDGFNGYLVPKGDINQMVE
                     KVDQLLNNTQKLQQFSINSIESAQQYNATTISTKWQNILN"
     gene            complement(3491..6952)
                     /gene="sdrE"
                     /locus_tag="RFE25_002099"
     CDS             complement(3491..6952)
                     /gene="sdrE"
                     /locus_tag="RFE25_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin SdrE"
                     /protein_id="HDU2817138.1"
                     /translation="MINRDNKKAITKKGMISNRLNKFSIRKYTVGTASILVGTTLIFG
                     LGNQEAKAAENTSTENAKQDDATTSDNKEVVSETENNSTTENDSTNPIKKETNTDSQP
                     EAKEESTTSSTQQQQNNVTATTETKPQNIEKENVKPSTDKTATEDTSVILEEKKAPNY
                     TNNDVTTKPSTSEIQTKPTTPQESTNIENSQPQPTPSKVDNQVTDATNPKEPVNVSKE
                     ELKNNPEKLKELVRNDNNTDRSTKPVATAPTSVAPKRLNAKMRFAVAQPAAVASNNVN
                     DLITVTKQTIKVGDGKDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTINYDKNVIPSD
                     LTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKYEDIKARLTLYSYIDKQA
                     VPNETSLNLTFATAGKETSQNVSVDYQDPMVHGDSNIQSIFTKLDENKQTIEQQIYVN
                     PLKKTATNTKVDIAGSQVDDYGNIKLGNGSTIIDQNTEIKVYKVNPNQQLPQSNRIYD
                     FSQYEDVTSQFDNKKSFSNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMR
                     TTDKYGYYNYAGYSNFIVTSNDTGGGDGTVKPEEKLYKIGDYVWEDVDKDGVQGTDSK
                     EKPMANVLVTLTYPDGTTKSVRTDANGHYEFGGLKDGETYTVKFETPAGYLPTKVNGT
                     TDGEKDSNGSSITVKINGKDDMSLDTGFYKEPKYNLGDYVWEDTNKDGIQDANEPGIK
                     DVKVTLKDSTGKVIGTTTTDASGKYKFTDLDNGNYTVEFETPAGYTPTVKNTTAEDKD
                     SNGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKDVKVTL
                     LNEKGEVIGTTKTDENGKYRFDNLDSGKYKVIFEKPAGLTQTVTNTTEDDKDADGGEV
                     DVTITDHDDFTLDNGYFEEDTSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDAGKHTPVKPMSTTKDHHNKAKALPETGSENNGSNNATLFGGLFAALGSLLLFG
                     RRKKQNK"
     gene            complement(7346..11503)
                     /gene="sdrD"
                     /locus_tag="RFE25_002100"
     CDS             complement(7346..11503)
                     /gene="sdrD"
                     /locus_tag="RFE25_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin SdrD"
                     /protein_id="HDU2817139.1"
                     /translation="MLNRENKTAITRKGMVSNRLNKFSIRKYTVGTASILVGTTLIFG
                     LGNQEAKAAESTNKELNEATTSASDNQSSDKVDMQQLNQEDNTKNDNQKEMVSSQGNE
                     TTSNGNKSIEKESVQSTTGNKVEVSTAKSDEQASPKSTNEDLNTKQTISNQEGLQPDL
                     LENKSVVNVQPTNEENKKVDAKTESTTLNVKSDAIKSNAETLVDNNSNSNNENNADII
                     LPKSTAPKSLNTRMRMAAIQPNSTDSKNVNDLITSNTTLTVVDADNSKTIVPAQDYLS
                     LKSQITVDDKVKSGDYFTIKYSDTVQVYGLNPEDIKNIGDIKDPNNGETIATAKHDTA
                     NNLITYTFTDYVDRFNSVKMGINYSIYMDADTIPVDKKDVPFSVTIGNQITTTTADIT
                     YPAYKEADNNSIGSAFTETVSHVGNVEDPGYYNQVVYVNPMDKDLKGAKLKVEAYHPK
                     YPTNIGQINQNVTNIKIYRVPEGYTLNKGYDVNTNDLVDVTDEFKNKTTYGSNQSVNL
                     DFGDITSAYVVMVNTKFQYTNSESPTLVQMATLSSTGNKSVSTGNALGFTNNQSGGAG
                     QEVYKIGNYVWEDTNKNGVQELGEKGVGNVTVTVFDNNTNTKVGEAVTKEDGSYLIPN
                     LPNGDYRVEFSNLPKGYEVTPSKQGNNEELDSNGLSSVITVNGKDNLSADLGIYKPKY
                     NLGDYVWEDTNKNGIQDQDEKGISGVTVTLKDENGNVLKTVTTDADGKYKFTDLDNGN
                     YKVEFTTPEGYTPTTVTSGSDIEKDSNGLTTTGVINGADNMTLDSGFYKTPKYNLGNY
                     VWEDTNKDGKQDSTEKGISGVTVTLKNENGEVLQTTKTDKDGKYQFTGLENGTYKVEF
                     ETPSGYTPTQVGSGTDEGIDSNGTSTTGVIKDKDNDTIDSGFYKPTYNLGDYVWEDTN
                     KNGVQDKDEKGISGVTVTLKDENDKVLKTVTTDENGKYQFTDLNNGTYKVEFETPSGY
                     TPTSVTSGNDTEKDSNGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQ
                     DSTEKGIKDVKVILLNEKGEVIGTTKTDENGKYRFDNLDSGKYKVIFEKPTGLTQTGT
                     NTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDAGKHTPVKPMSTTKDHHNKAKALPETGNENSGSNNATLFGGLFAALGSLLLFG
                     RRKKQNK"
     gene            complement(11870..14773)
                     /gene="sdrC"
                     /locus_tag="RFE25_002101"
     CDS             complement(11870..14773)
                     /gene="sdrC"
                     /locus_tag="RFE25_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin SdrC"
                     /protein_id="HDU2817140.1"
                     /translation="MNNKKTATNRKGMIPNRLNKFSIRKYSVGTASILVGTTLIFGLS
                     GHEAKAAEHTNGELNQSKNETTAPSENKTTEKVDSRQLKDNTQTATADQPKVTMSDSA
                     TVKETSSNMQSPQNATASQSTTQTSNVTTNDKSSTTYSNETDKSNLTQAKNVSTTPKT
                     TTIKQRALNRMAVNTVAAPQQGTNVNDKVHFTNIDIAIDKGHVNKTTGNTEFWATSSD
                     VLKLKANYTIDDSVKEGDTFTFKYGQYFRPGSVRLPSQTQNLYNAQGNIIAKGIYDSK
                     TNTTTYTFTNYVDQYTNVSGSFEQVAFAKRENATTDKTAYKMEVTLGNDTYSKDVIVD
                     YGNQKGQQLISSTNYINNEDLSRNMTVYVNQPKKTYTKETFVTNLTGYKFNPDAKNFK
                     IYEVTDQNQFVDSFTPDTSKLKDVTGQFDVIYSNDNKTATVDLLNGQSSSDKQYIIQQ
                     VAYPDNSSTDNGKIDYTLETQNGKSSWSNSYSNVNGSSTANGDQKKYNLGDYVWEDTN
                     KDGKQDANEKGIKGVYVILKDSNGKELDRTTTDENGKYQFTGLSNGTYSVEFSTPAGY
                     TPTTANAGTDDAVDSDGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQ
                     DSTEKGIKGVKVTLQNEKGEVIGTTETDGNGKYRFDNLDSGKYKVIFEKPAGLTQTGT
                     NTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGKHTPT
                     KPMSTVKDQHKTAKALPETGSENNNSNNGTLFGGLFAALGSLLLFGRRKKQNK"
     gene            complement(15203..15769)
                     /locus_tag="RFE25_002102"
     CDS             complement(15203..15769)
                     /locus_tag="RFE25_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDU2817141.1"
                     /translation="MKGLIIIGSAQVNSHTSALARYLTEHFKTHDIEAEIFDLAEKPL
                     NQLDFSGTTPSIDEIKQNMKDLKEKAMAADFLILGTPNYHGSYSGILKNALDHLNMDY
                     FKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDFAKNEDGSYYLN
                     DSEFQLRARLFVDQIVSFVNNSPYEHLK"
     gene            complement(15791..16660)
                     /locus_tag="RFE25_002103"
     CDS             complement(15791..16660)
                     /locus_tag="RFE25_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDU2817142.1"
                     /translation="MIKLIATDMDGTLLNAAHEISQPNIDAIKYAQEQGITVVIATGR
                     AFYEAQAPVADTDLTVPYICLNGAEVRDETFNVMSTSHLNKSLVHKITNVLKDAGIYY
                     QVYTSRAIYTEDPQRDLDIYIDIAERAGQHANVERIKNGIQRRIDNGTLKVVDNYDAI
                     ENIPGELIMKILAFDGNLEKIDKASKILAESPNLAISSSSRGNIEITHSDAQKGIALE
                     TIAERLGIEMKDVMAIGDNLNDLSMLEKVGYPVAMENGAEEVKKIAKYVTDTNENSGV
                     GKAIMKLLREQQV"
     gene            complement(16807..17277)
                     /locus_tag="RFE25_002104"
     CDS             complement(16807..17277)
                     /locus_tag="RFE25_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDU2817143.1"
                     /translation="MTNDIYFMTLAIEEAKKAAQLGEVPIGAIITKDDEVIARAHNLR
                     ETLQQPTAHAEHIAIERAAKVLGSWRLEGCTLYVTLEPCVMCAGTIVMSRIPRVVYGA
                     DDPKGGCSGSLMNLLQQSNFNHRAIVDKGVLKEACSTLLTTFFKNLRANKKSTN"
     gene            17344..>17887
                     /locus_tag="RFE25_002105"
     CDS             17344..>17887
                     /locus_tag="RFE25_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDU2817144.1"
                     /translation="MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSD
                     FYEDISKWSFQTEMFFLCNRYKQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSPVEFQK
                     FSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREY
                     YESLQSNGSNVVLIDTTSIDF"
BASE COUNT         5086 a         3089 c         2686 g         7026 t
ORIGIN      
        1 aatatcatat gattaattca aacgcgtaac attagttgcg cgtttttatt ataccttcta
       61 gagttgtata tctcttttat aaatcttctc atttgatgtg cctgaggcat aaatcaatat
      121 cctaagctct acaatgatat attggtcgta gttgattgaa taactactat cattataaat
      181 atcaaaattt gttgttttat aaataaacac atcatccagt taaaagaagt aattaaatat
      241 tatgtgatat aattataaaa aatagatata agtggtgttg taaatgaatt attttgtagg
      301 taatagttta ggtgttaatt taactgggat agaaaaagca attattaatc gtttaaattt
      361 atttaaagaa atgggaagac cagcgcaatg tgtatttctg tcatggaata gatatttata
      421 tagaaatgcc caaaattata ttactagttc tgactatatt aatatgtatg atttcttcca
      481 agaagcaaca tatttagaac gcaatgaacc atttgactgg ttgtcgtatt ggactgatga
      541 atgtcattat actttaaaac atgttgaaaa tagtcatgac tttagaatat atgatcaaga
      601 gcgtttctta atgtatgccc attttcaaga tcctaaatat cgtatattag attatgtgaa
      661 tcattttgat agtcaaagac gaaaagtaaa acgtgatttt tatgatgtgc gtggcttttt
      721 aagttgtagt aggattcttg ttgataaaca acaaacatta tgtgaatttt tctataatcc
      781 agaaggtgac acaaaattag aaaagtattt ttcttacaag gatggcaaac cagaagtaca
      841 aaaaattatt gtttactatg ctaacaaaca atatttcttt aataatgaaa cggaattagg
      901 cgcatttttc attaaacaac tatatcaaca tggggattta tttttcagtg accgtaatgt
      961 gtatacagca cctattttca acttaacacc tgagtcaatc ccagtagtag ctgtgcttca
     1021 cagtacacac attaaaaata ttgatgcatt agattcatcg ccatttaaaa atgtatataa
     1081 agcgatgttt gaaaatttat ctcgatatcg tgcaattatc gtttctactg agcagcaaaa
     1141 attagatgtt gaaaaacgta ttaaccatac tattccaatt gttaatattc ctgtcggcta
     1201 tagtgaaaca attgatacac cagtccaaac attagatcag cgcagtgtta aattaatttc
     1261 cgttgctcgt tattcacctg aaaaacaatt acatcaacaa attgaattaa ttaaacgctt
     1321 agtatcgtat gtcccaaaaa tagagcttca tatgtatggt tttggttctg aaagtaaaaa
     1381 attaaatgaa ttgatacaaa aatatggatt ggaaaatcat gtttacttac gtggcttttt
     1441 aagcaatcta aaccaagaat acagcgatgc ttacttaagt ttaataacaa gtaacatgga
     1501 aggtttctct ttagcgctac ttgaatcttt agcacatggt gttccagtta ttagttatga
     1561 tattaaatat ggacctaacg aattgattac gcctgatttc aatggttatt taattactaa
     1621 aaatgatgaa gatgccctat ttgataaagt aaaatatgtg attgatcatc ctgaagtaca
     1681 acaacgactg tcaaaaggta gtttggcaaa agcgcaacaa tatagtaaag cgtcgttaat
     1741 taaacaatgg gaccaatttg ttcgtcttat ataaatgtac ttcaccttta tttttataaa
     1801 aaaaagcgtt ttcctatgtc atttaactaa acatgtaagt tcgtatgaac gttgtttgtt
     1861 aaatagatga ttctaggaaa atgctttttt cttttgactt agtttaaaat attttgccac
     1921 tttgtactga tagtagttgc attgtactgt tgtgcagatt ctatgctatt aatcgaaaac
     1981 tgttgcaatt tttgagtatt atttagtaat tgatcgacct tttcaaccat ttgattgatg
     2041 tcacctttag gtactaaata gccattaaat ccatcttgaa tcagttctga tggcccataa
     2101 tctatatcat aactgatcac tggtgtacct actgaaagcg actctaaaat tgctaagcca
     2161 aaaccttcca ttttacttgt cgataacatc agttctgctt tagcaatctc ttcattaata
     2221 tgcgtcttaa aaccatgaaa tttaacatgt tccgataaat gataatcttc tacaagttgt
     2281 cgatattctg acaaaccatt tccatgtcca taaatattca attgaatatt gggatgtttt
     2341 gttactaatt gcttgatcac ttcaatttga tgtttaattt gtttattttc aacgaggcga
     2401 gcaattgata tgatatgatt tttctccttt tgattgatgt caaattgata ctttaaattt
     2461 gccacgtagc caaccggaat attgataact ggtattttat tttcaatata ttgtgaaata
     2521 tcttggcatt gctgttctgt tgatacaaca atcgctttat aacgtgttaa attattaaat
     2581 actgttttat aaaaactttt tataccatta ccggtaccgg ataaatgtgt actatggagc
     2641 acaacaacaa ctggaatact ttgatttaat cccgctataa catttcctaa ttcatgagga
     2701 cgatctaata tgatttgatc attattttta cataattgat ggagaaaata ttgaactaat
     2761 tcatcttctg tatcaaaaaa ttgttgctgc tggtcttcat ttaagataac ctttgtgagc
     2821 gtgttttttc cttttatatc gtcgaaatat ttttggatga cgatttcccc attaggtgta
     2881 tagtaatttt cgagtacaat ccgttgtcct tcgcctaaaa ttcgagaaca acttaaaaag
     2941 cctcttccat catacaattc gcgttttact tttcttcttt tatgatcaaa ataattcaca
     3001 tagtttaatt gatgatactg tttatctaaa aaatgagcat acattacaaa ttgctcttca
     3061 tcatatattc tgacatcatt tgaattttcc acaaatttca atgtgtacct acatgacttt
     3121 tcccaatact gtatccagtt aacttgcttt gtctttttat aattgattgc tttttgaaaa
     3181 tagtcataca ttgtaaatac atcattttca atctgatgtt gcttcgcata tgtgtatgaa
     3241 taaggattcc atttaacata tacacatttt gaagatatgc cgtgttgttt gaacaacttc
     3301 aatctattta tttgcgcttt ttctacacct gtaattttac tttctaaaat tgttcctaaa
     3361 atgtaattca tattatcgcc tcatataagt tttattccgt atctttattg tttattttat
     3421 atgaaaaata catctattgc atgtgtaatc ataaaaaaaa ccaggccaca aggacctggg
     3481 tcatattgta ttatttgttt tgttttttgc gacgaccgaa taacaataat gaacctaatg
     3541 ctgcaaataa tccaccaaat aacgttgcgt tatttgagcc gttattttca ctacctgttt
     3601 ctggtaatgc ttttgcttta ttgtgatggt ctttagtagt actcattggt ttaacaggtg
     3661 tatgttttcc tgcatccgag tccgaatcgc tatctgagtc tgaatcactg tctgagtctg
     3721 agtcgctatc tgagtctgag tcgctgtccg aatctgagtc gctatctgag tctgagtcgc
     3781 tgtctgaatc tgagtcgcta tctgagtctg aatcactgtc cgaatctgag tcgctatctg
     3841 aatctgaatc gctgtctgag tctgagtcac tgtctgagtc tgagtcgcta tctgagtctg
     3901 agtcactgtc tgaatctgag tcgctatctg agtctgaatc gctgtctgaa tctgagtcgc
     3961 tatctgagtc tgaatcgctg tccgaatctg agtcgctatc tgagtctgag tcgctgtctg
     4021 agtctgagtc gctatctgag tctgagtcgc tgtctgaatc tgaatcgcta tctgagtctg
     4081 aatcactgtc tgaatctgag tcgctgtctg agtctgaatc actgtctgag tctgaatcac
     4141 tgtctgatgt atcttcttca aagtatccgt tatcaagtgt gaaatcatca tgatccgtaa
     4201 ttgttacgtc aacttcgcca ccatcggcat ctttatcatc ttcagttgta tttgtaactg
     4261 tttgtgttaa gccagcaggc ttttcaaaaa taactttgta tttaccgcta tctaaattat
     4321 cgaaacgata tttaccattt tcatctgttt tagttgttcc aattacttcg cctttttcat
     4381 ttaataaagt aactttaaca tctttgatac ctttttcagt tgaatcttgt ttaccgtctt
     4441 tattactgtc gtaccaaaca taatcaccta aactgtattt tggtgtttta tagaaaccac
     4501 tgtctaatgt catattatct gcatctttaa tgacacctgt tgttgttaaa ccattagaat
     4561 ctttatcttc agctgtagta tttttaaccg ttggcgtgta acctgctggt gtttcaaatt
     4621 ctactgtata gttaccatta tctaaatctg taaatttata tttacccgag gcatcagtag
     4681 tagttgtacc aataactttt ccagtactat cttttaatgt aaccttaaca tctttgatac
     4741 caggttcatt agcatcttgg ataccatctt tatttgtatc ttcccataca tagtcaccaa
     4801 gattatattt aggttcttta taaaaaccag tgtctaaaga catatcatct ttaccattaa
     4861 ttttaacagt tatagaacta ccatttgagt ctttttcacc atcagttgtt ccatttactt
     4921 ttgttggaag atatccagct ggcgtttcga atttaactgt ataagtttct ccgtctttca
     4981 aaccaccgaa ttcataatga ccgttagcat ctgttcttac tgattttgta gtaccgtccg
     5041 ggtaagttaa tgtaactaaa acgtttgcca ttggcttttc tttcgaatct gtaccttgga
     5101 caccgtcttt atcaacgtct tcccatacat agtcaccaat tttgtataac ttttcttcag
     5161 gtttaacagt accgtcgcca ccgccagtgt cattagaagt tacgatgaag tttgaatatc
     5221 ctgcataatt ataataacca tatttatcag ttgttctcat actagtacct tgagcaatat
     5281 ctagttcgcc atctgatgta ggtgtatatt tactaacaac tttgataata taggctgaat
     5341 taatatcacc aaaatccaat gttgctacat tattactaaa tgatttttta ttatcaaatt
     5401 gacttgttac atcttcgtat tgactaaaat catagattct attactttga ggcaattgtt
     5461 gattagggtt aactttataa acttttattt ctgtattttg gtcaataatg gtactaccat
     5521 ttcctagttt aatatttcca taatcatcta cttgactacc agctatatca actttagtgt
     5581 tagttgctgt ttttttcaaa ggattaacat aaatttgttg ttcaatagtt tgtttgtttt
     5641 catctaactt tgtaaagata gattgaatgt ttgaatcacc atgaaccatt gggtcttgat
     5701 aatcaacaga aacgttttgg ctagtttctt tacctgctgt tgcaaacgtt aaattcaaac
     5761 tagtttcatt aggtactgct tgcttatcaa tatatgagta taaagttaaa cgtgctttta
     5821 tatcttcata tttatctaca taatctgtaa atgtatatgt gatttgctta gtcgctttat
     5881 caaatgttcc tttggcaatg acctctcctg atggatcagt aatatcgata ggatcatttt
     5941 tatctgttaa atccgaagga attacattct tatcataatt aatcgtcatt gtatcgcctt
     6001 ttttgacttt attgtcaatt gtaaactctg tatcatattc aatatcttta ccgtcatgcg
     6061 ctgctgccac attatcttta ccatcgccaa ctttgatcgt ctgtttcgta actgtaatta
     6121 agtcatttac attatttgaa gcaactgctg ctggttgtgc aactgcaaaa cgcattttcg
     6181 catttaatcg ttttggtgca acacttgttg gagctgtagc aactggttta gttgaacgat
     6241 ctgtattgtt atcatttcta actaattctt ttaatttctc aggattattt ttaagttctt
     6301 cttttgacac atttactggt tcttttggat tagttgcatc tgtaacttga ttgtctactt
     6361 ttgaaggcgt tggttgcggt tgtgaatttt caatatttgt agattcttga ggtgtagttg
     6421 gttttgtttg aatttcactt gtagatggtt ttgtagttac atcgttattt gtataatttg
     6481 gtgctttctt ctcttctaaa ataacagatg tatcttctgt cgcagtttta tcagttgaag
     6541 gtttaacatt ttctttttca atgttttgag gcttagtttc agttgtagct gtaacgttat
     6601 tttgctgttg ttgagtactt gatgtagttg attcttcttt agcttctggt tgtgaatcag
     6661 tatttgtttc tttcttaatt ggatttgttg aatcattttc tgttgtcgaa ttattttcag
     6721 tttccgacac tacttcttta ttatcactag tcgttgcatc atcttgtttc gcattttctg
     6781 tactagtgtt ttcagcagct ttagcttctt ggttccctag accaaaaatc aatgtcgtac
     6841 ctactaaaat cgatgcagtt cctacagtat actttctaat cgaaaatttg tttaagcgat
     6901 ttgaaatcat accctttttt gttattgcct ttttattatc cctgttaatc atataaatct
     6961 cctttaaaat atcaatattt gcaaaaaatt aatattttta catataaaaa tttgtattcc
     7021 catcgtaata catttttaga taaatcacaa tactttaaat aaatttattt atctaagact
     7081 gttattttac actttggttt gaataaatta attctagtaa tttttaatta ttcgtttgtt
     7141 ttttatatca attgttttaa atggtttgat actgtgttta attgcttttc ttattcgttt
     7201 gtacttttaa tgtaaagatg aattaaattt atgttgattt atgttatatt ttttaaaaaa
     7261 ttgcactatt taatctcaaa cataagatac atttcataaa ttttgaaata aaaaaccagg
     7321 cctcacggac ctggtataag ctgtattatt tattttgttt tttacgacga ccgaataaca
     7381 ataatgatcc taatgctgcg aataatccgc caaataacgt tgcgttattt gagccactat
     7441 tttcattacc tgtttctggt aatgcttttg ctttattgtg atggtcttta gtagtactca
     7501 ttggtttaac aggtgtgtgc ttacctgcat ctgagtctga atcactgtct gaatctgagt
     7561 cgctatctga gtctgaatcg ctgtccgaat ctgagtcact atctgagtct gaatcgctgt
     7621 ctgaatctga gtcgctatct gagtctgagt cgctatctga atctgaatca ctgtctgagt
     7681 ctgagtcgct gtccgaatct gagtcgctgt ctgaatctga atcgctatct gagtctgagt
     7741 ctgaatcgct atctgaatct gagtcgctgt ctgaatctga atcactgtct gaatctgaat
     7801 cgctgtctga atctgaatcg ctatctgagt ctgagtcgct atctgagtct gaatcgctgt
     7861 ctgagtctga gtcgctatct gagtctgaat cgctgtccga atctgagtcg ctatctgagt
     7921 ctgagtcgct gtctgaatct gaatcgctgt ctgagtctga atcgctatct gaatctgaat
     7981 cgctatctga gtctgagtca ctatctgagt ctgagtcgct gtctgaatct gaatcactat
     8041 ctgaatctga atcactatct gaatctgaat cactatctga gtctgaatcg ctgtctgagt
     8101 ctgaatcgct gtccgaatct gagtcgctat ctgatgtttc ttcttcgtag tagccattat
     8161 caagtgtgaa atcatcatga tccgtaattg ttacatcaac ttcgccacca tcggcatctt
     8221 tatcatcttc agttgtattt gtacctgttt gtgttaagcc agtaggcttt tcaaaaataa
     8281 ctttgtattt accgctatct aaattatcaa agcggtattt accattttca tctgttttag
     8341 ttgttccaat tacttcgcct ttttcattta ataaaataac tttaacatct ttgatacctt
     8401 tttcagttga atcttgtttg ccgtctttat tactgtcgta ccaaacataa tcacctaaac
     8461 tatattttgg tgttttatag aaaccactgt ctaatgtcat gttatctgca tctttaatga
     8521 cacctgttgt tgttaaacca ttagaatctt tttcagtatc atttccagaa gttactgaag
     8581 ttggtgtata acctgatggt gtctcgaatt caactttata agttccattg tttaaatcag
     8641 tgaattgata tttaccattt tcatctgttg taactgtttt taaaactttg tcgttttcat
     8701 cttttaacgt aactgttaca cctgaaatac ccttttcatc tttatcttga acaccgtttt
     8761 tatttgtatc ttcccataca tagtcaccta agttgtaagt cggtttgtag aaaccagagt
     8821 caatagtatc gttatcttta tctttaatga cacctgttgt tgatgtacca tttgaatcta
     8881 taccttcatc agttcctgaa cctacttgtg ttggtgtgta acctgatggt gtttcgaatt
     8941 caactttata agttccattt tctaatccag taaattgata tttaccatct ttatctgttt
     9001 tagttgtttg taaaacttca ccgttttcat ttttcaatgt aactgttacg cctgaaatac
     9061 ctttttcagt tgaatcctgc ttaccatctt tatttgtatc ttcccataca taattaccta
     9121 aattatattt tggtgttttg tagaatccac tatctaatgt catgttatca gcaccattaa
     9181 taacacctgt tgttgttaaa ccattagagt ctttttcaat gtcgctacca gatgttactg
     9241 tagtcggtgt atagccttct ggtgtagtaa attcaacttt ataattacca ttatctaaat
     9301 cagtaaattt atatttgcca tctgcgtctg ttgtaactgt ttttaacacg ttaccgtttt
     9361 catcttttaa tgttaccgtt acgccagata tacctttttc atcttggtct tggataccat
     9421 ttttatttgt atcttcccag acatagtcac ctaagttgta tttaggtttg taaataccta
     9481 agtctgcaga taagttatct ttgccattaa ctgtaataac tgaagataag ccgtttgaat
     9541 ctaattcttc gttattacct tgttttgaag gggttacttc ataacctttt ggtaagtttg
     9601 aaaattctac acggtaatct ccattaggta agtttggaat caagtatgac ccatcttctt
     9661 tagtaactgc ttctcctact tttgtatttg tattattatc aaatacagtt acagttacat
     9721 tgccaacgcc tttttctcct aattcttgaa caccgttttt attagtatct tcccatacgt
     9781 agttaccaat tttatatact tcttgaccag ctccgccact ttggttatta gtaaatccta
     9841 aagcattgcc agtagaaacg gatttattac ctgttgaaga taaagtagcc atttgaacaa
     9901 gtgttgggct ttcgctattt gtatattgga attttgtatt aaccattaca acatatgctg
     9961 atgtaatatc accaaaatca agattaacac tttgatttga tccatacgtc gttttatttt
    10021 taaattcatc agttacgtct accaaatcat tagtattaac gtcatatcct ttattcaatg
    10081 tatatccttc aggaacacga tatattttta tatttgtaac attttgatta atttgaccaa
    10141 tattagttgg atatttcgga tggtacgctt caacttttaa cttagcacct tttaaatcct
    10201 tatccatagg attaacatat actacctggt tatagtaacc agggtcttca acatttccta
    10261 catgagaaac tgtctctgta aaagctgatc ctattgaatt attgtcagct tctttataag
    10321 ccggataagt gatatctgct gttgtagttg taatttgatt tccaatagtt acactaaaag
    10381 gaacatcttt cttgtcaaca ggaattgtat ctgcatccat ataaattgag taattaatac
    10441 ccatttttac tgaattaaat cgatcaacat aatctgtaaa tgtatatgta attaaattat
    10501 ttgcagtatc atgttttgca gtcgcaattg tttcaccatt atttggatct ttaatatcac
    10561 caatattttt aatatcttcc ggattcaatc catatacttg tactgtatct gagtatttaa
    10621 ttgtgaaata atcacctgat ttaactttgt catcaactgt aatttgtgat tttaatgata
    10681 aataatcttg ggctggtaca atcgttttgc tattatctgc atcaacgaca gttaatgttg
    10741 tatttgatgt gattaaatca ttaacatttt tagaatctgt tgagtttggt tgtattgctg
    10801 ccatacgcat tcttgtattc aaacttttag gtgctgtact ttttggcaaa atgatatctg
    10861 cattattttc attatttgaa ttactattgt tatcaacaag agtttcagca ttactcttga
    10921 tagcatcact tttaacattt aatgtagttg attcagtttt cgcatctacc tttttgtttt
    10981 cctcattagt tggttgaaca tttaccactg atttattctc tagcaaatca ggttgtaacc
    11041 cttcttgatt acttatagtt tgtttagtgt ttaaatcttc attcgtagat tttggtgaag
    11101 cttgctcatc tgatttggca gttgaaactt caactttatt tccagtggta gattgtacac
    11161 tttctttttc tattgattta ttcccatttg aagtcgtttc attaccttga gatgatacca
    11221 tttctttttg attatcattt ttagtattgt cttcttgatt tagttgctgc atatcaactt
    11281 tatcactcga ttgattatca cttgctgaag ttgtcgcttc gttcaattct ttattagtac
    11341 tttctgcagc ctttgcttct tggttcccca gaccaaaaat taatgttgta cctactaaaa
    11401 ttgatgctgt tcccactgtg tactttctaa tcgaaaattt atttaatcga ttggatacca
    11461 tgccttttct tgttattgcc gttttatttt ctctgtttag cattagatta ctcctaattc
    11521 atcaaatttt taaataatac aattgtttta aatacaaaaa tgtatatcaa tatagtatta
    11581 catttttaga taaagcacaa tactttaatt atttttcttt atcgtaaaac gttatttaac
    11641 atttgtgttt aaataaaagt ttttatgagt tttgtaatct ttatttaatt atcataaaaa
    11701 atagtattat ttgcccttaa aattaatatc ttagcttttc taattcatag acaattacat
    11761 ttctgtaaca aattaaattg catctattcc ttaaagattt tttgttttat atctgggaat
    11821 ttctaaacag aaaaaaccag gccacatgga cctggttaag ttaatcatat tatttatttt
    11881 gttttttacg acgaccgaat aacaataatg atcctaatgc cgcgaataat ccaccgaata
    11941 atgtgccatt atttgaatta ttattttcac tacctgtttc tggtaatgct ttagctgttt
    12001 tatgctgatc tttaaccgta ctcattggtt tagtcggagt atgtttacct gcatctgaat
    12061 ctgaatcgct atccgaatct gaatcgctgt ctgagtcgct atctgagtct gaatcgctgt
    12121 ctgagtctga gtcgctatct gaatctgagt cgctgtctga atctgaatcg ctatctgaat
    12181 ctgaatcgct gtctgaatct gagtcgctgt ctgaatctga atcgctatct gagtctgagt
    12241 cgctgtctga atctgagtcg ctatctgagt ctgaatcgct gtcagaatct gagtcgttgt
    12301 ctgagtccga atcgctatct gaatctgagt cgctatccga atctgaatcg ctgtctgaat
    12361 ctgagtcgct gtctgagtct gagtcactgt ctgaatctga gtcgctgtct gaatctgagt
    12421 cgctatctga gtctgagtcg ctatccgaat ctgattcgct gtctgaatct gagtcgctgt
    12481 ccgaatctga atcactatct gagtctgagt cgctgtctga gtcgctatct gagtctgagt
    12541 cgctatctga gtctgagtca ctatctgaat ctgagtcgct atctgagtct gaatcgctgt
    12601 ccgaatctga gtcactatct gatgtttctt cttcgtagta gccattatca agtgtgaaat
    12661 catcatgatc cgtaattgtt acatcaactt cgccaccatc ggcatcttta tcatcttcag
    12721 ttgtatttgt acctgtttga gttaaaccag caggcttttc aaagataact ttgtatttac
    12781 cactatctaa attatcaaag cggtatttac catttccatc tgtttcagtt gtaccaatta
    12841 cttcgccttt ttcgttttgc aaagtaactt taacaccttt aattcctttt tcagtcgaat
    12901 cttgtttacc atctttatta ctgtcgtacc aaacataatc acctaaacta tattttggtg
    12961 ttttgtagaa tccactatct aatgtcatgt tgtcagcgtc tttaatgaca cctgttgtag
    13021 ttagtccatc agaatctaca gcatcatctg tacctgcatt tgcagttgtc ggtgtataac
    13081 cggctggtgt tgaaaactct acactataag ttccattgct taaaccagtg aactgatatt
    13141 taccattttc atctgttgtc gtacgatcta attctttacc gttactatct ttaagaatga
    13201 cataaacacc tttaatccct ttttcattgg catcttgttt accatcttta tttgtatctt
    13261 cccatacata gtcacctaga ttatatttct tttggtcgcc atttgcagtt gatgagccat
    13321 tcacatttga ataactgttt gaccaactac tttttccatt ttgtgtttct aaagtataat
    13381 caattttccc attatctgtt gaactattat ctggataagc aacttgttga atgatgtact
    13441 gtttatcact actagattga ccattcaata aatctactgt cgccgtctta ttatcattac
    13501 tataaataac atcgaattga ccagtaacat ctttaagttt tgaagtatct ggggtgaaac
    13561 tatccacaaa ttgattttga tctgtcactt cgtaaatttt gaagttttta gcatctggat
    13621 taaatttata accagttaaa tttgttacaa atgtttcttt tgtataggtc tttttaggtt
    13681 gatttacata aacagtcata ttacgtgaca aatcttcatt attaatataa tttgtactcg
    13741 aaataagttg ttgacctttt tgattaccat aatcgacaat gacatcttta ctatatgtat
    13801 cattacctaa agttacttcc attttataag cagttttatc agttgttgca ttttcacgtt
    13861 tcgcaaatgc gacttgttca aagctaccgc taacatttgt gtattgatct acataattcg
    13921 taaaagtata cgttgttgta tttgttttac tatcgtaaat accttttgca ataatattac
    13981 cttgggcatt atataaattt tgagtttgtg aaggtaatct tacagaacct ggacggaaat
    14041 attgaccata tttaaaagta aatgtatcgc cctctttaac agaatcatcg attgtgtaat
    14101 tcgcttttaa ttttaaaaca tcacttgaag ttgcccaaaa ttcagtattt cctgttgttt
    14161 tattaacatg tcctttatca atcgcaatat caatgttcgt aaaatgtact ttatcattaa
    14221 catttgttcc ttgttgtgga gctgcaacag tattcactgc catgcgattt aaagctcttt
    14281 gtttaatagt cgttgtttta ggtgtagttg aaacgttttt tgcttgtgtt aaattacttt
    14341 tatcagtttc attactatat gtagttgatg atttatcatt tgttgttaca ttgctagttt
    14401 gtgtagtaga ttgactagct gtagcgtttt gtggtgattg catgttacta ctagtttctt
    14461 taactgttgc actatcactc attgtcactt taggctgatc tgcagttgca gtttgcgtat
    14521 tgtcttttag ttgacgacta tcaacttttt cagttgtttt attctcactt ggggctgtcg
    14581 tttcattttt tgattgattt aattctccat tcgtatgttc tgccgcttta gcttcatgac
    14641 cacttaaccc aaaaatcaat gttgtcccta ctaaaattga agcagtacct acagaatact
    14701 ttcttatcga aaatttgttt aatcgatttg gtatcatgcc ttttctattt gttgctgtct
    14761 ttttattatt catttaataa tactccttta aaatatcaaa atttgataaa tataatattt
    14821 tgcatatata aatttctgca ttactatcgt aatataaatt tcaataaagt gcaatacttt
    14881 aattattttt ctttatttta caatgttatt tgctacaaat attaatatga atcacagttt
    14941 aagaattgca atttttaata ctttttttct ttaattgctt taaattattt atctatattt
    15001 ttaaaactct cttttaatct aagcttgttt tcaattcgct attacatctt attttaatta
    15061 ataacattgc tcacaacagt aatctcaaag gcttactatt ggtgcattag aacaaaaaaa
    15121 ggcatgtgac ttaaaagcat tctcaatgaa ataccttaag ctacatacct atttttaatg
    15181 tatatttaca tattttttaa tattatttta aatgttcata tggactatta ttcacaaaag
    15241 atacaatttg atcgacaaat aatcttgctc gtaattggaa ttcactatca tttaagtaat
    15301 atgaaccatc ttcattttta gcaaaatcag aatcatgtgt tgctatttga gttggtacag
    15361 caatgcctag taaacttctg acgattactc ttaaatgtga caatggctct gaactaacaa
    15421 taccaccact atttcctatt aagcctacag gtttcatttt aaaataatcc atatttagat
    15481 gatctaatgc atttttcaat attccagaat atgaaccatg atagtttggc gttcctaata
    15541 ttaaaaagtc cgccgccatt gctttctctt ttaaatcttt catattttgt ttgatttcat
    15601 caatagacgg tgttgttcct gaaaaatcta attgatttaa cggtttttct gctaaatcga
    15661 atatttccgc ttcaatatca tgtgttttaa aatgctcagt taagtatctt gctagtgcac
    15721 ttgtatgtga attcacttgt gcactgccaa taataattaa tcctttcata tttgacccct
    15781 ctttttttta ttaaacttgt tgttcacgta ataatttcat aatagctttt ccaacaccac
    15841 tattttcatt cgtatctgtg acatatttcg ctattttttt aacttcttct gcaccatttt
    15901 ccatcgcaac tggatagcca actttctcta acattgataa gtcatttaaa ttgtcaccta
    15961 ttgccatgac atctttcatt tcaatcccta atctttcggc aattgtttct agcgcaatac
    16021 ctttttgtgc atctgaatgc gttatttcta tatttcctct cgaagatgat gatatagcta
    16081 aattcggaga ttcagctaaa attttactag ctttgtcaat tttttctaaa tttccatcaa
    16141 atgctaatat tttcataatt aattcaccag gtatgttttc aatagcatca taattatcaa
    16201 caactttcaa cgtaccatta tctatgcgtc tttgaatacc atttttaata cgctcaacgt
    16261 ttgcatgttg acctgcacgc tcagcaatat ctatgtaaat gtctaaatct ctttgtggat
    16321 cttcagtata aatcgcacga ctcgtgtata cttgataata aatacctgca tcttttaaaa
    16381 catttgtaat tttgtgtact aacgatttat taaggtgtga agtgctcatt acattgaaag
    16441 tttcatcacg tacttcagca ccattcaaac aaatatatgg tactgttaaa tctgtgtcag
    16501 caactggtgc ttgtgcttca taaaatgctc gacctgtcgc gataacaacc gttatccctt
    16561 gttcttgagc gtatttaatc gcatcaatat taggttgaga aatttcatgt gctgcattaa
    16621 gtagcgtgcc atccatatca gtggctatta gttttatcat tatgttacct cgtttcgtaa
    16681 atttaaaatc ttgttcttaa ataagaatat atactcagcg cacatacttt tctattaaca
    16741 tttatattgt cattaattta tcatataatg taattctaac aaattttaat tagtatgtac
    16801 tatcgtctaa ttggtggatt tcttattggc tcttaagttt ttaaaaaatg ttgttaataa
    16861 tgtgctacat gcttctttaa gtacaccttt atcaacaatt gcacgatgat taaaattaga
    16921 ttgttgcaat aaattcatta aactgccact acaaccacct ttaggatcat ctgcgccata
    16981 gacgactctt ggaatgcgac tcattacaat tgttcctgcg cacatgacac atggttctaa
    17041 ggttacatat aatgtgcaac cttctaaacg ccaactacct aacactttgg ctgcacgttc
    17101 aattgcaata tgttcagcat gcgccgttgg ttgttgtagt gtttctctta aattatgtgc
    17161 tctagcgata acttcatcat ctttagtgat gatagcacct ataggtactt cgcctagttg
    17221 agctgctttt ttagcttctt caatcgctaa tgtcataaaa tatatatcat ttgtcattta
    17281 tgtccagata cctcacttat ggtacaatac tcaatgtcta ttttaacatt tggagatgtg
    17341 aatatgaaca aaccttttat agcaattgaa ggtcctattg gcgtaggtaa atcttcactt
    17401 gcacacaaat taagtcaaac tttagatttt tatgaagaaa aagaaatcat cacagaaaat
    17461 ccatttttat cagactttta tgaagatatc tctaaatgga gttttcaaac tgaaatgttc
    17521 tttttatgca atagatataa gcaatttcaa gatgtaacac aactaaatca aggtgtagtt
    17581 agtgattatc atatacataa aaataagata tttgctaaaa atactttgag tcctgttgaa
    17641 tttcagaaat tcagtaaaat ttatgatatt ttaactgaag atatgattat gccgaatatg
    17701 attatctttt tagatgcaga ccttgatgtg ttaaaatcta gaattgctaa acgtaaccgt
    17761 agttttgagc atcaaataga agatgaatat ctgttaaagt taaaaaaaga ttatcgtgag
    17821 tattatgagt ccttacaaag taatggttca aatgtagttt taatcgatac aacttctatt
    17881 gattttc
//
LOCUS       DAPDIM010000057        17560 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000057 DAPDIM010000000
VERSION     DAPDIM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 17560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17560
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.057"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..191)
                     /locus_tag="RFE25_002106"
     CDS             complement(<1..191)
                     /locus_tag="RFE25_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HDU2817145.1"
                     /translation="MSYSIGIDYGTASGRVFLINTTNGQVVSKFVKPYTHGVIESELN
                     GLKIPHTYALQNSNDYLEI"
     gene            complement(350..1228)
                     /gene="hchA"
                     /locus_tag="RFE25_002107"
     CDS             complement(350..1228)
                     /gene="hchA"
                     /locus_tag="RFE25_002107"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HDU2817146.1"
                     /translation="MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEH
                     KGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLS
                     GYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGH
                     AAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPD
                     SLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNE
                     LGKLAVNEMLNAIQNK"
     gene            complement(1498..2685)
                     /locus_tag="RFE25_002108"
     CDS             complement(1498..2685)
                     /locus_tag="RFE25_002108"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDU2817147.1"
                     /translation="MVQSLHEFLEENINYLKENGLYNEIDTIEGANGPEIKINGKSYI
                     NLSSNNYLGLATNEDLKSAAKAAIDTHGVGAGAVRTINGTLDLHDELEETLAKFKGTE
                     AAIAYQSGFNCNMAAISAVMNKNDAILSDELNHASIIDGCRLSKAKIIRVNHSDMDDL
                     RAKAKEAVESGQYNKVMYITDGVFSMDGDVAKLPEIVEIAEEFGLLTYVDDAHGSGVM
                     GKGAGTVKHFGLQDKIDFQIGTLSKAIGVVGGYVAGTKELIDWLKAQSRPFLFSTSLA
                     PGDTKAITEAVKKLMDSTELHDKLWDNAQYLKNGLSKLGYDTGESETPITPVIIGDEK
                     TTQEFSKRLKDEGVYVKSIVFPTVPRGTGRVRNMPTAAHTKDMLDEAIAAYEKVGKEM
                     KLI"
     gene            2856..4031
                     /locus_tag="RFE25_002109"
     CDS             2856..4031
                     /locus_tag="RFE25_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDU2817148.1"
                     /translation="MLDWFQLANNKENKTIQLRRYLHQYPELSFEEFQTHDYIVNQLS
                     QLSCDIETPIGRNGIKATFKGLGTGPTIALRADFDALPVEELNDVPYKSKNPGCMHAC
                     GHDGHTAILLTVAEILDEHKHLLEGNVVLIFQYGEEIMPGGSQEMIDAGCLENVDRIY
                     GTHLWSGYPTGTIHSRAGAIMASPDEFSVTIKGRGGHGAKPHETIDPIVIMAEFILSA
                     QKIISRTIDPVKQAVLSFGMIQAGTTDSVIPDQAFCKGTVRTFDSDIQNHVMDKMDKL
                     LQGLAIANDINYDLNYIKGYLPVHNNEKAYQVIKEATNDLHVRFNESDLMMIGEDFSH
                     YLKVRPGAFFLTGCGNESKGITAPHHNPKFDIDEKSLKYAVAVFLKIIELEQVFKTN"
     gene            complement(4313..5497)
                     /gene="tuf"
                     /locus_tag="RFE25_002110"
     CDS             complement(4313..5497)
                     /gene="tuf"
                     /locus_tag="RFE25_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDU2817149.1"
                     /translation="MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVA
                     QSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGG
                     ILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSE
                     YDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDV
                     FSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIG
                     ALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFR
                     TTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEI
                     IK"
     gene            complement(5714..7795)
                     /gene="fusA"
                     /locus_tag="RFE25_002111"
     CDS             complement(5714..7795)
                     /gene="fusA"
                     /locus_tag="RFE25_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDU2817150.1"
                     /translation="MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETH
                     EGASQMDWMEQEQDRGITITSAATTAAWEGHRVNIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA
                     PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAV
                     AETSDELMEKYLGDEEISVSELKEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVID
                     YLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDPYVGKLTFFRVYSGT
                     MTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGE
                     KNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVII
                     GGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKSSAQVQGKFSRQSGGRGQYGD
                     VHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLIDVKAKL
                     YDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVT
                     SRRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSI
                     AEDIIKKNKGE"
     gene            complement(7918..8388)
                     /gene="rpsG"
                     /locus_tag="RFE25_002112"
     CDS             complement(7918..8388)
                     /gene="rpsG"
                     /locus_tag="RFE25_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDU2817151.1"
                     /translation="MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILY
                     SAFDLVEQRSGRDALEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKAFAHYRW"
     gene            complement(8454..8867)
                     /gene="rpsL"
                     /locus_tag="RFE25_002113"
     CDS             complement(8454..8867)
                     /gene="rpsL"
                     /locus_tag="RFE25_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDU2817152.1"
                     /translation="MPTINQLVRKPRQSKIKKSDSPALNKGFNSKKKKFTDLNSPQKR
                     GVCTRVGTMTPKKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKD
                     LPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN"
     gene            complement(8965..9219)
                     /locus_tag="RFE25_002114"
     CDS             complement(8965..9219)
                     /locus_tag="RFE25_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDU2817153.1"
                     /translation="MSKEKVARFNKQHFVVGLKETLKALKKDQVTSLIIAEDVEVYLM
                     TRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK"
     gene            complement(9356..12952)
                     /gene="rpoC"
                     /locus_tag="RFE25_002115"
     CDS             complement(9356..12952)
                     /gene="rpoC"
                     /locus_tag="RFE25_002115"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDU2817154.1"
                     /translation="MKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFG
                     PTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIP
                     SRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFRDYYDKYPGQFVAK
                     MGAEGIKDLLEEIDLDEELKLLRDELESATGQRLTRAIKRLEVVESFRNSGNKPSWMI
                     LDVLPIIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEK
                     RMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSV
                     IAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDVL
                     EEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHV
                     PLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFN
                     NTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEEQNKKILATSVGKIIFNEIIPDSF
                     AYINEPTQENLERKTPNRYFIDPTTLGEGGLKEYFENEELIEPFNKKFLGNIIAEVFN
                     RFSITDTSMMLDRMKDLGFKFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQF
                     NRGLITEEERYNAVVEIWTDAKDQIQGELMQSLDKTNPIFMMSDSGARGNASNFTQLA
                     GMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRR
                     LVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEII
                     IRPDELITPEIAKKITDAGIEQMYIRSAFTCNARHGVCEKCYGKNLATGEKVEVGEAV
                     GTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEARNPKGQAVITEIEGV
                     VEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEIGQPVQRGEVLTEGSIEPKNYL
                     SVAGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSL
                     VDIHNFTDANREAFKHRKRPATAKPVLLGITKASLETESFLSAASFQETTRVLTDAAI
                     KGKRDDLLGLKENVIIGKLIPAGTGMRRYSDVKYEKTAKPVAEVESQTEVTE"
     gene            complement(13116..16667)
                     /gene="rpoB"
                     /locus_tag="RFE25_002116"
     CDS             complement(13116..16667)
                     /gene="rpoB"
                     /locus_tag="RFE25_002116"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDU2817155.1"
                     /translation="MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREG
                     LIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKE
                     TGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA
                     TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLR
                     NTLEKDGTENTEQALLEIYERLRPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTN
                     KKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMDVLESNANSEVFELH
                     GSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLS
                     GIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINI
                     RPVIASIKEFFGSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYS
                     HYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQIDYLTAD
                     EEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATAC
                     IPFLENDDSNRALMGANMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVE
                     HVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSGTCYNQRPIVAVGDVVEYNEI
                     LADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEA
                     RDTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAE
                     ERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIV
                     QKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLGVPSRMNIGQVL
                     ELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRI
                     SVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA
                     AYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGLDVKVMD
                     EQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD"
     gene            complement(16882..17490)
                     /locus_tag="RFE25_002117"
     CDS             complement(16882..17490)
                     /locus_tag="RFE25_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDU2817156.1"
                     /translation="MSHYYDEDPSVISNEQRIQYQLNHHKIDLITDNGVFSKDKVDYG
                     SDVLVQTFLKAHPPGPSKRIADVGCGYGPIGLMIAKVSPHHSITMLDVNHRALALVEK
                     NKKLNGIDNVIVKESDALSAVEDKSFDFILTNPPIRAGKETVHRIFEQALHRLDSNGE
                     LFVVIQKKQGMPSAKKRMNELFGNVEVVNKDKGYYILRSIKA"
BASE COUNT         5264 a         3443 c         2823 g         6030 t
ORIGIN      
        1 ataatttcta aataatcatt actattttga agtgcatatg tatgtggtat tttcaaacca
       61 tttaattcac tttcaatgac accatgtgta tatggtttca caaattttga tactacttga
      121 ccgttagttg tattaattaa aaacacacgg cctgaagcag ttccataatc aattccaatg
      181 ctatacgaca tcatgtttcc tccatatcgc tagttgcggt tattagtttt gcaagcgttt
      241 tcttaaatca tactcataat aggttctatt ttacaagtat cacttaaatt ttgccaaaaa
      301 aaagagtcct catacattta catatgaggc tcctctaatt aatatttaat tatttatttt
      361 gtattgcatt taacatttca ttaactgcta attttcctaa ctcatttgaa gctaaaggac
      421 tgtcacctgt taataattta cgatctttta acgttcttcc tgtcatatcg tcgttaacta
      481 cttttaatcc ttgtttagtt aataaatcag caactaacca tttcaagcgt ccaggtaaat
      541 aacctatttc aatatttgca ccttcatcta atgagtcagg gaagacacaa acagagtatc
      601 cttctaatgg agatttttct ctgttaagcc ctgctgaaag tagtgctgct ggtccatgac
      661 ataatgtaac tataaagcgg tcattgtcta atgcccaatc taatgtttgt tgaacgtcct
      721 cactttcaga aataccaaca actgcagcat gtccgcctgg gataaagaca gataaatagt
      781 ctgaatcagg tcctaattca tttttaatca catctgctaa tttttttggc tgttttaatt
      841 tttctttcaa tttattataa gtacttataa ctgcctcgtc ttcagttggc atagcccata
      901 attctaattt aactggataa ccagataatg tcgcaacatc aacgtcaaaa cctgcttcca
      961 ttaaatgatg taaaggtaat aacatttcaa caggatgatt acccgtagag aacatttttc
     1021 cattttccaa taatacatat ctctcttcag cagcaatcat caatactttc catttaccat
     1081 ctttataggc acctttgtgt tcaacaccat caaaatctgt tttaggtgct gtatattgac
     1141 taagggaata tggtgatggg aaaaatgcgt tatcttctgc tttatctggc gttggttgct
     1201 tacttaattc atttacatct tgtgacatag tttattccta ctttctctat atagttacta
     1261 ctagtataga catatactac acactataaa catgtattac tattaaaata ctcattatca
     1321 aaaataatca aaatgaattt ctttgtaaaa aatacaacta aattctacaa gatgctttta
     1381 aaattcaaac ttcaattttg gggagcacta aacattgtta taagaactta ctgttaataa
     1441 actaaacatt aaaaaaagcc cacgacaata tttgccgtgg gaataaataa ataaatatta
     1501 aatcaacttc atttcttttc ctactttttc ataagccgca attgcttcat ctaacatgtc
     1561 ttttgtatgt gcagctgtag gcatatttct tacacgtcct gtacctcttg gtactgttgg
     1621 gaaaacgata gatttcacat agacaccttc gtcttttaaa cgcttactaa attcttgagt
     1681 tgttttttca tcaccaataa ttactggtgt aattggagtt tctgactcac ctgtatcata
     1741 tcctaatttt gacaatccat tttttaaata ttgtgcattg tcccataatt tatcatgtaa
     1801 ttcagttgaa tccattaact ttttaactgc ttcagttatt gctttggtat ccccaggtgc
     1861 taatgatgta gagaataaga atggtcgtga ttgtgctttt aaccaatcta ttaactcttt
     1921 tgtacctgct acatagccgc caacgacacc aattgcttta gaaagcgtac ctatttggaa
     1981 atcgatttta tcttgtaaac caaaatgttt aaccgtacca gcgcctttac ccataacacc
     2041 tgaaccatga gcgtcgtcaa cataagttaa taaaccaaat tcttctgcaa tttctacaat
     2101 ttcaggtaat ttagccacat caccatccat actaaaaacg ccatcagtga tatacatcac
     2161 tttattgtat tgacctgatt caactgcttc ttttgctttc gcacgtaaat catccatgtc
     2221 tgaatggtta actcgaataa ttttagcttt agataagcga catccatcaa taattgatgc
     2281 atgattaagc tcatctgata aaatagcatc atttttattc atgacagctg aaatagcagc
     2341 catattacaa ttaaatcctg actgataagc tattgcagct tctgttcctt taaattttgc
     2401 tagtgtttct tctaattcgt cgtgtaaatc taatgtacca ttgattgtac gaacagcgcc
     2461 tgcacctaca ccatgtgtat caatagctgc ttttgcagct gatttcaaat cttcatttgt
     2521 tgctagtcct aaataattat ttgaagataa gttaatgtat gatttcccat tgattttgat
     2581 ttctggtccg tttgcacctt caattgtatc tatttcatta tacaaaccat tttcttttag
     2641 ataatttata ttttcctcta aaaactcatg taatgattga accacagtat ataatccccc
     2701 ttaagtattg tttggtaata cctttatcat acagtaattc tacataactt gaaagcctta
     2761 tcattcatag ataaaatatc tcaaagcaat catttagtac gataatttca taaaatgtta
     2821 tactataaac attattttag aaagtagtga taagggtgtt agattggttc caactagcaa
     2881 ataataaaga aaataaaaca attcaactca gacgttattt acaccaatat cctgagttat
     2941 cttttgaaga atttcaaaca catgattata ttgttaacca attaagccag ttatcttgtg
     3001 atattgaaac tcctatcggc cgcaatggta tcaaagccac atttaaaggc ttgggcacag
     3061 gacctaccat tgcattaaga gctgactttg atgcgttacc tgtcgaggaa ttaaacgatg
     3121 tgccttataa gtctaaaaat ccaggatgta tgcatgcgtg tgggcatgat ggtcatacag
     3181 caattttact tactgtagca gagattttag atgaacataa acatttatta gaaggtaatg
     3241 ttgtattaat attccagtac ggtgaagaaa tcatgccagg tggttctcaa gaaatgatag
     3301 atgctggatg tctggaaaat gtagatagaa tttacggtac acatttatgg agtggttatc
     3361 ctactggaac tattcattca cgtgcggggg caatcatggc ctctccagat gaatttagcg
     3421 tcacaattaa aggtcgtggt ggtcatggtg ccaaacctca tgaaaccatt gacccaatag
     3481 taatcatggc agagttcatt ttaagtgcac aaaaaataat ttcacgtacg atcgatccag
     3541 ttaaacaagc tgtactttca tttggaatga ttcaagcagg taccacagat agcgttattc
     3601 ctgatcaagc attttgtaaa ggtacagtta gaactttcga ttcagatata cagaatcatg
     3661 taatggacaa aatggataag cttctacaag gtttagcaat agcaaatgat attaactatg
     3721 atttgaatta tattaaaggg tatttgcctg tccataataa cgagaaagca tatcaagtta
     3781 ttaaagaagc aacaaatgac ttacatgtac gctttaatga atcagattta atgatgattg
     3841 gagaagattt ttcacattat ttgaaagtac gaccaggtgc attctttctg actggttgtg
     3901 gtaatgaaag taaaggtatt acagcgccac accataatcc caaatttgat attgatgaaa
     3961 aatcattaaa atacgctgta gctgtatttt taaaaatcat tgaattagag caagtattta
     4021 aaacaaatta agcatttaaa ttaattgaaa gatatgaatc tgggacataa actaatgaaa
     4081 tgctcccttc aaagtagaca ttgaaaaaat gaaaactttg aagggagcat tttacaatgt
     4141 ccaagactca acaattttat ttaaacagta ttatcagtta taagttttat tagtcagtct
     4201 ttcatcaatt attgttcttc taaatcgaat agccattaca aaatttacac attaaaaaaa
     4261 gacccctcga ttgagggatc ttctttttat ataaaatcta agaaattaga aattatttaa
     4321 tgatttcagt aacaacgcct gatcctacag tacgtccacc ttcgcggatt gagaaacgag
     4381 taccgtcttc aatcgcgatt ggagcgatta attctactgt catttcaacg ttatcaccag
     4441 gcattaccat ttcagtacct tctggtaagt gaacaacacc agttacgtca gtagtacgga
     4501 aatagaattg tggacgatag tttgagaaga atggagtgtg acgtccacct tcgtcttttg
     4561 ataatacgta tacttctgct ttaaattcag tatgtggtgt aattgaacca ggagcagcta
     4621 atacttgacc acgttgtacg tcttcacgag caacaccacg taataatgca ccaatgttgt
     4681 caccagcttc agcgtagtct aataatttac ggaacatttc aacacctgta acagttgttt
     4741 tagatgtgtc atgtaaaccg atgatttcaa cttcttcacc aactttgatt tgaccacgtt
     4801 caacacggcc tgtagcaaca gtaccacgac cagtgattga gaatacgtcc tcaactggca
     4861 tcatgaatgg tttgtcagaa tcacgttctg gagttggaat gtaagtatct acagcttcca
     4921 ttaattctaa gattttttct tcgtattgag catcgccttc taaagctttt aatgctgaac
     4981 cagcgattac aggtacatcg tcacctggga agtcatattc gcttaataag tcacgaactt
     5041 ccatttctac taattctaat aattcttcat cgtcaaccat gtcaactttg tttaagaata
     5101 ctactaatgc tggtacacca acgttacgtg ataaaagaat gtgttcacga gtttgtggca
     5161 ttggaccgtc agcagcagat actactaaga taccgccgtc catttgagca gcaccagtga
     5221 tcatgttttt aacgtagtca gcgtgtcctg ggcagtcaac gtgagcgtag tgacgtttgt
     5281 cagtttggta ctcaatgtga gaagtattga ttgtgatacc acgttctttt tcttctggag
     5341 cgttgtcaat catgtcatat gattgtgcaa ctgagtcacc attttttgct aatacagtag
     5401 cgattgctgc tgttaatgtt gttttaccat ggtcaacgtg accgatagta ccgatattgg
     5461 catgttcttt agaacgatcg aatttttctt ttgccattat aaaatctctc ctattctaat
     5521 taaaaataat atttaaattt atctctcatg atagtttctc accatcatga gaaattattt
     5581 atagcgatgc aaaaagaatt ttacaattct tttataatgc attcacccca aaaaatcaaa
     5641 ctataaagat gatagcttac atttaagctc accttgtatt ttaacctagg ctagctagtc
     5701 aaaacaagtt atattattca cctttatttt tcttgataat atcttcagcg attgattttg
     5761 gaacttcagc atagtgatcg aagtacatag tgtaagtacc gcgaccttga gtgtttgaac
     5821 gtaatgatgt tgcataaccg aacatttctg aaagtggtac ataagcatta acaacttgtg
     5881 cattaccacg aggttccata ccatcaacac gtccacgacg agatgttacg tcacccatga
     5941 tatcacccat gtactcttca ggcatttcaa tagttacttt catcattggt tctaagatta
     6001 caggatcaca ttttttagca gcttctttaa gtgctaatga tgcagcaatt ttgaaggcca
     6061 tttcagatga atcgacatca tggtatgaac catcatataa tttagcttta acatcaatta
     6121 aaggataacc tgctaagaca ccattttcca tagcatcttt aagaccagct tctactgatg
     6181 gaatgtattc acgaggaact acaccaccaa cgatagcgtt ttcgaattcg aaacctgcgc
     6241 ctgtttcgtt tggtgtgaat tcaatgtgaa catcaccgta ttgaccacga ccaccagatt
     6301 gacgagagaa tttaccttga acttgtgcag atgatttgaa tgtttcacga tatgaaacca
     6361 ttggagcacc tacgttacat tcaacgttga attctttctt catacggtct actaagatgt
     6421 ctaagtgaag ctcacccata ccaccgatga taacttgtcc agtttcttcg tcagtgtgtg
     6481 catggaatgt tgggtcttct tcttgtaatt taactaaagc ttgagtcatt ttatcttggt
     6541 cagctttaga ttttggctct actgataagt gaataactgg ctctgggaat tccattgatt
     6601 ccaagataat gtcatttttc tcaccacata aagtatcacc agtacctgta tctttaagac
     6661 ctaccgcagc cgcgatatct ccagagtata cagtatcgat ttcttgacgt gagttagcgt
     6721 gcatttgtaa taaacgacct acacgttcac gtttaccttt agtagagttc ttaacgtatg
     6781 aaccagatgt cattgtacct gaatacacac ggaagaatgt taatttacca acataagggt
     6841 cagtcataac tttgaacgct aatgcagcga attcagctga atcgtctgct ttcgcgatta
     6901 cttcttcttc agggttgcta gcacggtgac caataattgg tttaacgtct agtggtgaag
     6961 gtaagtaatc aattacagcg tcaagcatta attgaacacc tttgtttttg aaagctgtac
     7021 cacaaagtac tgggtagaat tctacgttag tagtagcttg gcggatagct tcttttaatt
     7081 cagaaactga aatttcttcg tcaccaagat atttttccat taattcgtcg ctagtttctg
     7141 caactgcttc gattaagcta gcacgagctt cttcagctct atctaagtgg tcttcaggaa
     7201 tttcaatttc ttcaatttca gtacctaaat catttgtata tttgaaacat ttcatttcaa
     7261 ctaagtcaat gattgcttcg aattcgtctt ccgcaccaat tggtaattgg attggagcag
     7321 cgttagcttg taaacgatca tgtaatgtac ttacagagta ttcgaagtta gcacctaatt
     7381 tgtccatttt gtttacaaat acgatacgtg gaacaccata agttgtagcc tgacgccaaa
     7441 ctgtttcagt ttgtggttca acacctgatt gtgcatcaag tactgtaact gctccgtcaa
     7501 gtacacgtaa tgaacgttca acttctacag tgaagtctac gtgtccaggt gtatcgataa
     7561 tgtttacacg gtgaccttcc caagctgctg ttgttgcagc agatgtgata gtaataccac
     7621 ggtcttgttc ttgctccatc cagtccattt gtgaagcacc ttcgtgtgtt tcaccaattt
     7681 tgtggatacg gccagtgtaa taaagaatac gttcagtcgt agtcgtttta ccagcatcaa
     7741 tgtgagccat gataccgata ttacgagttt tttctaatga aaattctcta gccatgtatt
     7801 ttttctcctt ccagtttata ttactgaata aatacgatag atatggcgat gccctaagca
     7861 tgaacgctta atgaaaattc attaatatag aacacactca gggtaaaagc ttttatctta
     7921 ccaacggtag tgagcaaatg ctttgtttgc ttcagccatt ttgtgagtgt cctcacgttt
     7981 cttaacggca ccacctgtat tatttgctgc atctaaaatt tcgttagcta aacgatcttc
     8041 catcgttttt tcaccacgaa gacgtgcata gttaactaac caacgtaaac ctaaagtagt
     8101 acgacgctct ggacgaactt ctactggtac ttgatagtta gaaccaccta cacgacgagc
     8161 tttaacttct aatactggca taatgttgtt gattgcttct tcgaatactt ctaatgcatc
     8221 acgaccactg cgttgttcaa ctaggtcgaa tgctgaataa agaattcttt gtgctgttcc
     8281 acgtttacca tctaacataa ttttgttaat taatttagtt actaacttag agttatgaat
     8341 tggatctggt aatacgtctc ttttaggtac tgatccttta cgaggcataa tgtaaatcct
     8401 cccttcctta tattaaatat tttaagttta agatttaatt aaaaactaaa ttcttagttt
     8461 ttaggtttct tagttccgta taatgaacga ccttgtctac gtccgtcaac acctgaagta
     8521 tcaagtgctc cacgtacaat atggtaacgc acacctggta agtcttttac acgtccacca
     8581 cgtacaagta caacactgtg ttcttgtaag ttatgtccga taccagggat gtatgcgtta
     8641 atttcgatgt tgtttgataa acgcacacgt gcatatttac gtaacgctga gttaggtttt
     8701 ttaggtgtca ttgtacctac acgagtacat acaccacgtt tttgtggtga gtttaagtca
     8761 gtaaattttt tctttttact gttgaaacct ttatttaaag ctggagaatc tgattttttg
     8821 attttgcttt gtcttggttt acgtactaat tggttaatag ttggcatgtg atatgtcctc
     8881 ctctcttcac tttttaatcc cacacatcca ggtggttcat ttttaggtta aataaaattt
     8941 agtaagtaaa acacttacta attctcattt aatcaatgct actattgtcg cattgacgtt
     9001 aatacctaca tgtttaccca aagcatgttt gcttttgaaa aaagatacag gtatattttt
     9061 ctgattgatt tggcttaaca cgcgagtcat taaatatact tcaacgtctt cagcaataat
     9121 caaagatgta acttgatctt tctttaacgc tttaagcgtt tctttaagac caactacaaa
     9181 atgttgtttg ttaaagcgtg caactttttc cttagacaat aatttatcct ccaaagttct
     9241 gcttgcatca acctttaata ttttaacatt gaacaagaga attcgtcaac attaaatcaa
     9301 ataatttaca taaaaataac aagaggctaa agcattagcc tctgttatat acttgttatt
     9361 ccgttacttc agtttgagat tcaacttctg caactggttt agctgttttt tcgtatttta
     9421 cgtcgctata acgtctcata ccagtaccag ctggaattaa cttaccaata attacgtttt
     9481 ctttaagacc taataagtca tcacgcttac ctttaattgc tgcatctgta agaactcttg
     9541 ttgtttcttg gaatgatgct gcagataaga aactttctgt ttcaagtgat gctttagtaa
     9601 taccaagtaa tactggttta gctgttgcag gacgcttacg gtgtttaaat gcttctctat
     9661 ttgcatctgt aaagttatga atatcaacta atgaacctgg taataacttc gtatcacctg
     9721 cttcgataat tctaacttta cgtaacattt gtcgaaccat aacctcaacg tgtttatcgt
     9781 cgatttctac accttgcata cggtaaactt tttgtacttc ttttaataag tagctttcag
     9841 tcgcgtttaa tccagcaaca gataagtaat tcttaggttc aatagaacct tcagttaata
     9901 cttcaccacg ttgaactggt tgaccgattt ctacaataat tcttgaagta cctgaagcaa
     9961 ggtatgatct tgtttcatta gcacctttaa caacaatttc ttgttgtcta tcttttgcta
    10021 atttaatatc ttctacgaca ccttcgattt ccgtaattac cgcttgacct ttagggttac
    10081 gtgcttcgaa aatctcttga atacgaggaa gaccttgtgt gatatcgcta cctgctaccc
    10141 cacctgtatg gaatgtacgc attgtaagct gtgtacctgg ttcaccgata gattgggctg
    10201 caattgtacc aactgcttca ccaacttcaa ctttttcacc agtagcaagg tttttaccgt
    10261 aacatttttc acaaacacca tgtcgtgcgt tacaagtaaa tgctgagcga atatacattt
    10321 gttcaatacc agcatctgta attttcttag caatttcagg tgtaattaat tcatcaggac
    10381 gaatgattat ttcatcagtt tcaggatgac gaattgtttc tttagaataa cgaccttcaa
    10441 tacgttcgat aaatggttca atcatttctg taccttcttt aatatcagaa actaataaac
    10501 ctctatcagt accacagtct tcttcacgaa caataacatc ttgtgccacg tcaacaagac
    10561 gacgagtaag atatcctgag tcagctgttt taagtgctgt atcggcaaga cctttacgtg
    10621 caccgtgagt tgagatgaag tattcaagta ctgttaaacc ttcacggaat gaagatgtga
    10681 ttggtaattc gataatctta ccagatggtg cggccatcaa tccacgcata cctgctaact
    10741 gtgtaaagtt agatgcgtta ccacgggcac ctgaatcact catcatgaag attgggttag
    10801 ttttatcaag tgattgcatc aattcacctt gaatttgatc ttttgcatct gtccaaattt
    10861 caacaactgc attatatctt tcttcttcag tgattaaacc acggttgaat tgttttgtaa
    10921 ttctgtcgac taatttttca tgctcatcaa gtatttgttg cttatcaggt aatactacga
    10981 tatcagcaac acctactgta ataccagctt tagatgagaa tttgaatcct aagtctttca
    11041 tacggtctaa catcattgat gtatcagtga tgctaaatct gttgaatact tctgcaataa
    11101 tattacctaa gaattttttg ttgaaaggtt caattaattc ttcattttca aagtattctt
    11161 ttaatccacc ttcacctaaa gttgtaggat cgatgaaata tctgtttggt gtctttcttt
    11221 ctaagttttc ttgcgtaggt tcattaatat aagcaaatga atctggaatg atttcattga
    11281 atataatttt acctactgac gtagcaagaa tctttttgtt ttgttcttca gtaaatgttg
    11341 gattattgaa cgaacttgca tgtacaccaa ttctagtgtg taaatgtaca aagccatttg
    11401 catatgcttt taatacttca tttgtattat taaagattgc gcctgtattt actgcatctt
    11461 ttctttctaa agtaaggtaa tagttaccaa gtaccatatc ttgtgatggt gtaactacag
    11521 gtttaccatc tttagggttc aagatgtttt gtgctgctaa catcaacatt cttgcttcag
    11581 cttgtgcctc ttttgataaa ggaacgtgaa ccgccatttg gtcaccgtca aagtcagcat
    11641 tataagctgt tgttacaagt ggatgtagac gaatcgcacg accttcaact aaagttggtt
    11701 caaatgcttg aataccaagt ctatgaagtg ttggtgcacg gttaagtaat acaggatgtt
    11761 ctctaattac ttcttccaat acgtcccaaa cttcatcatc catacgttcg attttactct
    11821 tcgcattttt aatgttagtt gcaatttcac gttgaactaa ttctttcatt acgaatggtt
    11881 taaatagttc aagtgccatt tcttttggta aaccacattg gtacattttc aagcttggac
    11941 ctactgcaat aactgaacgt cctgaatagt cgacacgttt accaagtaag ttttgacgga
    12001 aacgaccttg tttacctttt aacatatgag ataaagattt taatggacgg ttacctgggc
    12061 cagtaactgg acgaccacga cgaccattat caattaaagc gtcaacggct tcttgtaaca
    12121 tacgtttttc gttttgaacg atgataccag gtgcacctaa atctaataaa cgtttcaaac
    12181 gattatttcg attaattaca cgacggtata agtcgtttaa gtcacttgtt gcaaatcgtc
    12241 caccatctaa ttgaaccatt ggacgaattt ctggtgggat gattggaagt acatctaaaa
    12301 tcatccatga aggtttgtta cctgaattac ggaatgattc aacaacttct aaacgtttaa
    12361 ttgcacgagt aagtctttga ccagtagctg attccaactc atcgcgtaac aatttaagtt
    12421 cttcgtcaag atcaatctct tcaagtaaat ctttaatacc ttctgcaccc atttttgcaa
    12481 cgaattgacc tgggtattta tcataataat ctctgaattc agcttcagat aataaagttt
    12541 tcttttctaa accagttgga cctggatcta caacaacata agaagcaaag taaataacct
    12601 cttctaatgc tcttggtgac atgtcaagta ataatcccat acgacttggt atacctttga
    12661 aataccaaat gtgagaaact ggagcagcaa gttcaatgtg acccattctt tcacgacgta
    12721 ctttagattt agttacttca actccacatc tgtcacagac catgcctttg tagcgaacac
    12781 gtttgtattt accacaacta cattcccagt cttttgtagg tccgaaaatt ctttcacaga
    12841 atagaccatc tttttcaggt tttaatgtac ggtagttgat tgtttcaggt tttttaactt
    12901 caccaaaaga ccaagaacgg attttttcag gtgaagccaa tcctattttc atataatgga
    12961 aattatttac atcaatcaag gagcctacct ccttcaattt agattagctg tgctatttga
    13021 ttgatttgca tttatttaaa atggcttaaa gtactaaact gaatcatcaa taaaattcag
    13081 cttagtatct ttttgcctgt tttgtaaatt gcgtattaat cagtaacttc tttttgtgtt
    13141 tcaggagcat cattttgttg taaatctact ttgcgttcta caacatcatc gtcatcaacg
    13201 tctgtcattt cgatttcatt atcttgctca tccataactt ttacatctaa acctaaactt
    13261 tgtaattctt tcatcaatac tcggaatgat tctggaacac ttggtctaga gatgttttca
    13321 cctttaacaa tagcctcgta tgttttcaca cgtcctactg tatcatcgga tttgtaagtt
    13381 aagatttctt gtaatgtgta tgcagcacca tatgcttcaa gtgcccatac ctccatctca
    13441 ccgaaacgtt gtccaccgaa ttgcgcttta ccgccaagtg gttgttgtgt aacaagtgaa
    13501 tatggtcctg ttgaacgcgc atgtaattta tcatcaacca tgtgcgcaag tttcaacatg
    13561 tacattacac ctactgaaat acggttatcg aatggttcac ctgtacgtcc atcataaagt
    13621 acagttttac catcacgagc cataccagct tcttcaattg ttgaccatac atcgtcatcg
    13681 tttgcaccgt caaatactgg tgatgcaacg tgaataccaa gatttttagc agccatacct
    13741 aagtgtagct ctaatacttg tccgatgttc atacgagatg gtacaccaag aggatttaac
    13801 atgatatcga tcggacgtcc atctggtaag taaggcatat cttcttcagg aacaatctta
    13861 gaaatgacac ctttgttacc atgtcgacca cacatcttat caccaacatg aattttacgt
    13921 ttttgaacga tatatacacg tactaattgg tttacaccag gtgataatgt atcgtcgcct
    13981 tcttcacgat tgaatacttt tacatcaaga acgataccgc cagcgccgtg aggtacacgt
    14041 aatgaagtat ctctaacttc acgtgctttt tcaccaaaga ttgcatgtaa caatctttct
    14101 tcggcagtta actcagttac acctttaggc gttactttac caactaaaat atctccatct
    14161 tttacttctg caccaatata aacgatacca cgatcgtcta agttcttaag tgcactttca
    14221 gaaacattag gaatatctct tgtgatttct tcaggtccta acttagtatc acgtgcttct
    14281 gattcatact cttcaatatg aatagaagta tacacgtcat ctttcacaag tctttcactc
    14341 atgataacgg catcctcata gttgtaaccg tcccaagtca tgaaaccaac tactacgttt
    14401 ctacctaatg ccatttctcc taattccata gatggtccat ctgctaaaat ctcgttatac
    14461 tcaacaacat ctccaactgc aacgattgga cgttggttgt aacatgtacc tgagtttgaa
    14521 cgtttaaatt tagctaatgg atagcgatct aattcacctt catgctcaac gccgttctct
    14581 tcaactagac gacgtacaag aatttcatta gattcaacat gttcaacacg acctctgtgc
    14641 ttagctgtaa tagctgcacc agaatcacgt gctgcaacgt gttccatacc tgttccaaca
    14701 aatggtgctt ctggattcat caaaggcact gcttgacgtt gcatgttcgc acccatcaat
    14761 gcacggtttg agtcatcgtt ttctaagaat ggaatacatg ctgtcgctgc tgaaacaact
    14821 tgcttcggcg atacatccat ataatccatt ttttctttag ccataactgt attgttacca
    14881 cggaaacgac atacaacttc atcatccatg aaacgaccat tttcatctaa tttagagttt
    14941 gcttgtgcta caacatagct atcttcttcg tcagctgtta aatagtcaat ttgatcagtg
    15001 atagcatgtg tatctaaatc aactttacga tatggtgttt caataaagcc gaattcattt
    15061 acacgtgcat aacttgataa tgagttaatc aatccaatgt ttggtccctc aggtgtttca
    15121 attggacaca tacggccata gtgagagtag tgaacgtcac gtacttccat ttgagcacgt
    15181 tcacgtgtta aaccaccagg tcctaatgct gatagacgac gtttatgcgt taactcagct
    15241 aatgggtttg cttggtccat gaattgtgat aattgagagc taccaaagaa ttctttaata
    15301 gatgcaataa caggtcgaat attaattaat tgttgaggtg tgatagactc agtatcttga
    15361 attgacattc tttcacgtac aactctttcc attcttgata aaccgatacg gaattggttt
    15421 tgtagtaatt cacctacaga acgtaaacga cggttaccta aatggtcaat atcatctgta
    15481 tatccaatac cgcttaataa gttaaagaag taactcattg aagcaatgat atctgctggt
    15541 gtaatgcatt taacttctga gtcagggaaa gcattaccaa ttacagttgt cgtacgacct
    15601 tcatcatcgt taggaacata tactttaatt gattgaattt ctactggctc gtctataacg
    15661 ctaccatgca attcaaacac ttcgctgttt gcatttgatt caagtacatc catgatttcg
    15721 tcgattttac gacgatcaag cactgtacct tcttcaacta caatttcacc agtttcagta
    15781 tttacaattg gctcagctaa tttttgatta aataaacgat gttttaaatg taattttttg
    15841 tttgttttat aacgacccac gcttgctaag tcatagcgtt ttggatcaaa gaaacgtgaa
    15901 tacaatagac ttttagcatt ttcaacagtt ggtggttcac ctggacgtaa acgttcatag
    15961 atttctaata acgcttgttc agtgttttca gtgccgtctt tctctaaagt attacgtaaa
    16021 tattcattgt cacctaaaag gtcaacaatt tcttggtcac ttgagaaacc taatgcacgt
    16081 aacaatactg ttaatggtag tttacgtgtt ctatcaatac gtacgtatac aacatcttta
    16141 gcatctgttt catattctaa ccatgcacca cggtttggaa taattgttgc atcatagttt
    16201 tcacgaccat ttttgtcgat tttttcattg aaataaacgg atggtgaacg aactaattga
    16261 gatacgatta cacgttctgc accattgata acgaacgtac ctgtatcagt cattaatggg
    16321 aaatcaccca taaagacttc ttgttcttta acttctcctg tttctttaat gattagacgc
    16381 acttttacac gaagaggtgc agcataagta gcgtcacggt ttttagattc ttctaaatca
    16441 tattttggtt ctcctaaacg gtaatccaca aactctaatg acaaattacc agtaaaatct
    16501 tcaattggag aaatgtctct aaacatttcg attaaacctt ctcttaggaa ccactcgtaa
    16561 gatttagttt gaatttctat taagtttggt aattctaata cttctgaaat tctcgcgtag
    16621 tttctacgtt tacgatgtct tccatattgg acaacttgac ctgccaaaca gattcacccc
    16681 tcaaaaatta tgtgatccgc ttttagctaa ataccataag catattaata aaaagacaaa
    16741 aagaaaacgg caacactaat gatgacacca ttttcgattc tatatttatt cttaattaac
    16801 ttatctattt aacgtaaaag tacacactta ttgaacataa atttttacat tatataacta
    16861 taacagaata tccatttcat ttcaagcttt tatacttctc agaatgtaat atcctttatc
    16921 tttatttacc acttctacat ttccaaaaag ttcattcatt cttttctttg cagatggcat
    16981 accttgcttc ttctgaatta caacgaatag ttcaccgttc gagtctaatc tatgtaatgc
    17041 ttgctcgaat atacgatgca cggtttcttt ccctgctctt attggtggat tggttaaaat
    17101 aaaatcaaaa cttttgtctt ccacagcaga caaagcatca ctttccttta cgatcacatt
    17161 atcaatacca tttaattttt tgtttttttc aactaaggct agcgctctgt gattaacatc
    17221 tagcattgta attgaatgat gtggtgatac tttagcaatc atcaaaccaa ttggtccgta
    17281 accacaacca acatcggcaa ttcgcttact tggaccaggt ggatgcgctt ttaaaaaagt
    17341 ttgaacaaga acatctgaac cataatctac tttatctttc gaaaacactc cgttatcagt
    17401 tattaaatca attttatgat ggtttaattg atattgaata cgttgttcat tgctaattac
    17461 acttggatct tcatcgtaat aatgactcat tattccacct catcttcact ttgtaactcg
    17521 tcattataat tataacattt cactcagtct ttaaatgaat
//
LOCUS       DAPDIM010000058        16269 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000058 DAPDIM010000000
VERSION     DAPDIM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 16269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16269
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.058"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            59..1225
                     /gene="scpA"
                     /locus_tag="RFE25_002118"
     CDS             59..1225
                     /gene="scpA"
                     /locus_tag="RFE25_002118"
                     /EC_number="3.4.22.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease staphopain A"
                     /protein_id="HDU2817157.1"
                     /translation="MKRNFPKLIALSLIFSLSVTPIANAESNSNIKAKDKKHVQVNVE
                     DKSVPTDVRNLAQKDYLSYVTSLDKIYNKEKASYTLGEPFKIYKFNKKSDGNYYFPVL
                     NTEGNIDYIVTISPKITKYSSSSSKYTINVSPFLSKVLNQYKDQQITILTNSKGYYVV
                     TQNHKAKLVLKTPRLEDKKLKKTESIPTGNNVTQLKQKASVTMPTSQFKSNNYTYNEQ
                     YINKLENFKIRETQGNNGWCAGYTMSALLNATYNTNKYHAEAVMRFLHPNLQGQRFQF
                     TGLTPREMIYFGQTQGRSPQLLNRMTTYNEVDNLTKNNKGIAVLGSRVESRNGMHAGH
                     AMAVVGNAKLDNGQEVIIIWNPWDNGFMTQDAKNNVIPVSNGDHYRWYSSIYGY"
     gene            1256..1582
                     /locus_tag="RFE25_002119"
     CDS             1256..1582
                     /locus_tag="RFE25_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphostatin A"
                     /protein_id="HDU2817158.1"
                     /translation="MEQIELFSIDKFKCNSEAKYYLNIIEGEWHPQDLNDSPLKFILS
                     TSDDSDYICKYINTEHKQLTLYNKNNSSIVIEIFIPNDNKILLTIMNTEALGTSPRMT
                     FIKHKS"
     gene            complement(1874..2047)
                     /locus_tag="RFE25_002120"
     CDS             complement(1874..2047)
                     /locus_tag="RFE25_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NETI motif-containing protein"
                     /protein_id="HDU2817159.1"
                     /translation="MKFKVNENETIADCLSRMKMQGYMPVKRIEKPVFQEQKDGTVEV
                     SHQEIVFVGKKIQ"
     gene            complement(2028..2630)
                     /locus_tag="RFE25_002121"
     CDS             complement(2028..2630)
                     /locus_tag="RFE25_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HDU2817160.1"
                     /translation="MSFVTENPWLMVLTIFIINVCYVTFLTMRTILTLKGYRYIAASV
                     SFLEVLVYIVGLGLVMSNLDHIQNIIAYAFGFSIGIIVGMKIEEKLALGYTVVNVTSA
                     EYELDLPNELRNLGYGVTHYAAFGRDGSRMVMQILTPRKYERKLMDTIKNLDPKAFII
                     AYEPRNIHGGFWTKGIRRRKLKDYEPEELESVVEHEIQSK"
     gene            complement(2901..3722)
                     /gene="nadE"
                     /locus_tag="RFE25_002122"
     CDS             complement(2901..3722)
                     /gene="nadE"
                     /locus_tag="RFE25_002122"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDU2817161.1"
                     /translation="MSKLQDVIVQEMKVKKRIDSAEEIMELKQFIKNYVQSHSFIKSL
                     VLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAVKLPYGVQKDADEVDQALRFIEP
                     DEIVTVNIKPAVDQSVQSLKEAGIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTD
                     HSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKELYEKTPTADLEDDKP
                     QLPDEDALGVTYEAIDNYLEGKPVTPEEQKVIENHYIRNAHKRELAYTRYTWPKS"
     gene            complement(3715..5184)
                     /locus_tag="RFE25_002123"
     CDS             complement(3715..5184)
                     /locus_tag="RFE25_002123"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500623.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDU2817162.1"
                     /translation="MYQLEDDSLMLHNDLYQINMAESYWNDNIHEKMAVFDLYFRKMP
                     FNSGYAVFNGLKRVIDFIEHFGFSESDLEYLKSIGYKDDFLSYLKDLKFTGSIRSMQE
                     GELCFGNEPLLRVEAPLIQAQLIETILLNIVNFHTLITTKASRIRQIASNDKLMEFGT
                     RRAQEIDAALWGARAAYIGGFDSTSNVRAGKLFGIPVSGTHAHAFVQTYGDEYVAFKK
                     YAERHKNCVFLVDTFHTLKSGVPNAIKVAKELGDKINFVGIRLDSGDIAYLSKEARRM
                     LDEAGFTETKIIASNDLDEETITSLKAQGAKVDSWGVGTKLITGYDQPALGAVYKLVA
                     IENEEGSYSDRIKLSNNAEKVTTPGKKNVYRIINKKTGKAEGDYITLENENPYDEQPL
                     KLFHPVHTYKMKFIKSFEAIDLHHNIYENGKLVYQMPTEDESREYLAQGLQSIWDENK
                     RFLNPQEYPVDLSKACWDNKHKRIFEVAEHVKEMEEDNE"
     gene            5368..6444
                     /locus_tag="RFE25_002124"
     CDS             5368..6444
                     /locus_tag="RFE25_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide synthase oxygenase"
                     /protein_id="HDU2817163.1"
                     /translation="MLFKEAQAFIENMYKECHYETQIINKRLHDIELEIKETGTYTHT
                     EEELIYGAKMAWRNSNRCIGRLFWDSLNVIDARDVTDEASFLSSITYHITQATNEGKL
                     KPYITIYAPKDGPKIFNNQLIRYAGYDNCGDPAEKEVTRLANHLGWKGKGTNFDVLPL
                     IYQLPNESVKFYEYPTSLIKEVPIEHNHYPKLRKLNLKWYAVPIISNMDLKIGGIVYP
                     TAPFNGWYMVTEIGVRNFIDDYRYNLLEKVADAFEFDTLKNNSFNKDRALVELNYAVY
                     HSFKKEGVSIVDHLTAAKQFELFERNEAQQGRQVTGKWSWLAPPLSPTLTSNYHHGYD
                     NTVKDPNFFYKKKESNANQCPFHH"
     gene            6464..7258
                     /locus_tag="RFE25_002125"
     CDS             6464..7258
                     /locus_tag="RFE25_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDU2817164.1"
                     /translation="MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNLFEVIKAVADD
                     DTSIGVVPIENSIEGTINIVADALAQQDVFAHGEIRLDINFALYGNGTDSISDIKKVY
                     SIAPAISQTTNYIHQHQFDYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHI
                     EDYPHNVTRFLVIKNQQQFDQNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIE
                     SRPLKTQLGMYRFFVQADSAITTDIKKVIAILETLDFKVEMIGAFN"
     gene            7330..7437
                     /locus_tag="RFE25_002126"
     CDS             7330..7437
                     /locus_tag="RFE25_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817165.1"
                     /translation="MVDFLLFVLFLHDAAVYVSLPLVQAIANVTFYFSF"
     gene            complement(7448..9010)
                     /locus_tag="RFE25_002127"
     CDS             complement(7448..9010)
                     /locus_tag="RFE25_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDU2817166.1"
                     /translation="MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFL
                     LTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQV
                     SSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLS
                     MFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGT
                     LIGTPPLIILKGQYMQHFGHEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYL
                     PGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKKWEVTSSVADGTIAI
                     FISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGE
                     QLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAP
                     AAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPIV
                     LGIDINQPLPLK"
     gene            complement(9215..10312)
                     /locus_tag="RFE25_002128"
     CDS             complement(9215..10312)
                     /locus_tag="RFE25_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectate lyase"
                     /protein_id="HDU2817167.1"
                     /translation="MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYD
                     ICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRFGFYRGYNGHSHIHIKGGKFDMN
                     GVSYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSG
                     ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHA
                     SRHNRYYENIHIRNNIFEDIQGYALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNA
                     ADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHKDVLIVGNTFNNSTQ
                     SIHLEDIDTVFLSPVEAGIQVTTINIDEIKK"
     gene            10681..11241
                     /locus_tag="RFE25_002129"
     CDS             10681..11241
                     /locus_tag="RFE25_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDU2817168.1"
                     /translation="MTHRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNY
                     YQDHIFFLMDLHYLHDIHHPESKLFPPHNIVDTSGRELYGKVGKLYETIKAQPNVHFI
                     DKTRYDSFFGTPLDSLLRERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVA
                     SFNQKGHEWALAHFKNSLGAEVEQHV"
     gene            11294..12223
                     /locus_tag="RFE25_002130"
     CDS             11294..12223
                     /locus_tag="RFE25_002130"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDU2817169.1"
                     /translation="MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVS
                     AETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIAN
                     FETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQ
                     QDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQ
                     VNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGE
                     AFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK"
     gene            complement(12416..12589)
                     /locus_tag="RFE25_002131"
     CDS             complement(12416..12589)
                     /locus_tag="RFE25_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817170.1"
                     /translation="MIVVAVNFKWSFELYMLKVENRAMNRVHNNIYNFNHNEKGRKKT
                     KIYTQHRKYFKKM"
     gene            12641..14020
                     /locus_tag="RFE25_002132"
     CDS             12641..14020
                     /locus_tag="RFE25_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDU2817171.1"
                     /translation="MNIIEQKFYDSKAFFNTQQTKDISFRKDQLKKLSKAIKSYESDI
                     LEALYTDLGKNKVEAYATEIGITLKSIKNARKELKNWTKTKNVDTPLYLFPTKSYIKK
                     EPYGTVLIIAPFNYPFQLVFEPLIGAIAAGNTAIIKPSELTPNVARVIKRLINETFDA
                     NYIEVIEGGIEETQTLIHLPFDYVFFTGSENVGKIVYQAASENLVPVTLEMGGKSPVI
                     VDETANIKVASERICFGKFTNAGQTCVAPDYILVHESVKDDLITALSKTLREFYGQNI
                     QQSPDYGRIVNLKHYHRLTSLLNSAQMNIVFGGHSDEDERYIEPTLLDHVTSDSAIMQ
                     EEIFGPILPILTYQSLDEAIAFIHQRPKPLSLYLFSEDENATQRVINELSFGGGAIND
                     TLMHLANPKLPFGGVGASGMGRYHGKYSFDTFTHEKSYIFKSTRLESGVHLPPYKGKF
                     KYIKAFFKN"
     gene            complement(14140..15168)
                     /locus_tag="RFE25_002133"
     CDS             complement(14140..15168)
                     /locus_tag="RFE25_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDU2817172.1"
                     /translation="MTNGYIGSYTKKNGKGIYRFELNENQSRIDLLEIGFELEASTYL
                     VRNNEVLYGINKEGEQCGVASLKIDDNGELHLLNKCLSSKAGTGCYVSISEDKRYLFE
                     AVYGAGIIRMYELNTHTGEIIRLIQELAHDFPTGTHERQDHPHAHYINQTPDGKYVAV
                     TDLGADRIVTYKFDDNGFEFYKESLFKDSDGTRHIEFHDNGKFAYVVHELSNTVSVAE
                     YNDGKFEELERHLTIPENFDGDTKLAAVRLSHDQQFLYVSNRGHDSIAIFKVLDNGQH
                     LELVTITESGGQFPRDFNIASSDDLLVCAHEQGDSVVTVFERSKETGKITLCDNTRVA
                     SEGVCVIF"
     gene            15438..15839
                     /locus_tag="RFE25_002134"
     CDS             15438..15839
                     /locus_tag="RFE25_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YolD-like family protein"
                     /protein_id="HDU2817173.1"
                     /translation="MTSYEEETDYRNVPRELLDNNIPMGRGMIKWAPFATLPEQFETI
                     QQYIIDQNKITRPVLSDDQLAELNIRLHEALQYAQPVEVKFYNNGFVDSVRLTIYRID
                     AINYEIDGYVYNQQQRQKISIFDILDIVLLP"
     gene            complement(15857..16065)
                     /locus_tag="RFE25_002135"
                     /pseudo
     CDS             complement(15857..16065)
                     /locus_tag="RFE25_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5512 a         2828 c         2392 g         5537 t
ORIGIN      
        1 tgaaactctt aactaaattt aatataatta ttttataata aaataaagga gtttttatat
       61 gaaaagaaac tttccaaaat taatagcttt aagtttaata ttttctttaa gtgttacccc
      121 tattgcaaac gctgagagca attcaaatat caaagcaaaa gataagaagc atgtgcaagt
      181 taatgtcgag gacaagagtg ttcctactga cgtacgtaat ttagcgcaaa aagactatct
      241 ttcttatgtt acttcacttg ataaaatcta taataaagag aaagcctcgt atacacttgg
      301 tgaacctttt aaaatttata aattcaacaa aaagagtgat ggtaattatt attttccagt
      361 tttgaacact gaaggtaata tcgattatat agttacaatt tcaccaaaaa tcactaagta
      421 ttctagttca tcttctaaat acacaatcaa tgtttctcca tttttatcta aagtcttaaa
      481 tcaatataaa gatcaacaaa ttactatttt gacaaactca aaaggttact atgtggttac
      541 tcaaaatcat aaagctaaac tagtactaaa aacaccacgt ctagaagata aaaagttaaa
      601 aaagactgag agtataccta ctggcaataa tgtaacgcaa ctaaagcaaa aagcttctgt
      661 cactatgcca actagtcaat ttaaaagtaa taattatact tacaacgagc aatatataaa
      721 taaacttgag aatttcaaga taagagaaac tcaaggtaac aatggttggt gtgcaggcta
      781 tacgatgtct gcattactaa atgcgactta taatactaac aaatatcatg cagaagctgt
      841 gatgagattt ttacacccaa acttacaagg acaacgattc caatttactg gtttaacgcc
      901 aagagagatg atttattttg gacaaactca gggaagaagt ccacaacttc ttaatagaat
      961 gactacatat aatgaagttg acaatcttac taaaaataat aaaggaattg ctgttttagg
     1021 tagtagagta gaatcaagaa atggtatgca cgcagggcat gccatggcag ttgttgggaa
     1081 cgctaaatta gataatggac aagaggttat aattatatgg aatccatggg ataatggttt
     1141 tatgactcaa gatgctaaaa acaatgttat tccagtatcc aatggcgacc attatcgatg
     1201 gtattcatct atttatggtt attaaaattt gtattttaga aaggtaaata atattatgga
     1261 acaaattgaa ttatttagta ttgataaatt caaatgtaat tcagaggcta agtattatct
     1321 taatattatt gagggagaat ggcatcctca agatttaaat gatagtcctt taaaatttat
     1381 tctcagtacc tcagacgatt ctgattacat ttgcaaatat ataaatacag aacacaaaca
     1441 actcacatta tataataaaa ataatagctc aattgttatt gaaatattta taccaaatga
     1501 taataaaata ctactaacaa ttatgaacac agaagctttg ggaacttctc ctagaatgac
     1561 tttcattaag cataagtcat aagactatct agatatgatt aagtaaacta ttaatcttat
     1621 taaaggtctc taggaagaaa aaatttcatg cgatgagatt gttttagaaa aagcgacgat
     1681 atatataatc taacaataat ttttaaaata ttaagaaccc ccagcatatg ctttatatag
     1741 cttgctgggg gtttctcata caatatggat cgagcatctt gcatgtataa acaaataggc
     1801 tattcaaagt aaaattactc aaactttgaa tagcctttcc tcttcaaata gtctttattt
     1861 aaattggatt atgttattgg attttcttac ctacaaaaac gatttcttga tgtgatactt
     1921 caaccgtgcc atctttttgc tcttgaaaca cgggtttttc aatacgtttt accggcatat
     1981 acccttgcat tttcattcgt gacaaacaat cagcaattgt ttcattctca tttactttga
     2041 atttcatgtt ctactacact ttccagttct tctggttcat aatctttaag ctttctacga
     2101 cgaatgcctt tagtccagaa tccaccatgt atgtttcgag gttcatacgc aatgataaat
     2161 gctttcggat ctaaattttt tatcgtatcc atcaatttac gttcatattt tcttggtgtt
     2221 aaaatttgca tcaccatacg actaccatct ctaccaaacg cagcatagtg cgtaacgcca
     2281 tatcctaaat ttcgaagttc attcggtaaa tctaactcat attctgctga agttacattt
     2341 acaactgtat aacctaatgc cagtttttct tctattttca taccaacaat gatacctatt
     2401 gaaaaaccaa atgcgtaggc aataatattt tgaatatggt ctaaattaga cataaccaaa
     2461 cctaaaccaa cgatataaac taatacttct aaaaaactaa ctgatgcagc aatataacga
     2521 taacctttca acgttaaaat tgttcgcatc gttaaaaacg ttacataaca aacgttaatg
     2581 ataaatatag ttagtaccat taaccatgga ttttctgtta cgaatgacat aaggcgcccc
     2641 actctctttc aattacactt taaataccaa actgcttcaa cctaacctta atgaatgcat
     2701 attaatataa tatagtacga aaactctcat aaataaatag cgaatttgtc ataaataaaa
     2761 atttattctc aaatgaacat acttacttta gttcatacac tttcaattta tacactgaag
     2821 tagtctagct gaatgtggtt taatgttatt aattctaact catatttaat ttaagtcaca
     2881 cgttagaaga aaaaattaaa ttaggatttt ggccacgtgt atcttgtata tgcaagttca
     2941 cgtttgtgtg catttcgtat ataatgattt tcaattactt tttgttcttc tggcgtaact
     3001 ggcttacctt ctaaataatt atcaatcgcc tcataagtta cacctaatgc atcttcatct
     3061 ggaagctgtg gtttatcatc ttctaaatca gcagttggcg ttttttcata taattccttt
     3121 ggcgcaccaa gatacgctaa taattgacga ccttgtcgtt tattcaaacc aaatataggt
     3181 gcgatatctg cagcaccatc accgtacttc gtataaaacc cagttatatt ttcagctgaa
     3241 tgatctgttc ctactacaat accttgtcgg tttgaagcaa ttgaaaattg tactttcata
     3301 cgttcacgcg ctttttcatt tcctttttgg aaatctgtaa gaacaatacc agcttctttt
     3361 aatgattgca cactttgatc aactgcaggc ttaatattga ctgttactat ttcatctggt
     3421 tcaatgaatc gcaaagcttg gtcaacttca tcagcatctt tttgaactcc ataaggtaat
     3481 ttaactgcaa taaacgtaca atcaatgcct tcttcacgta attcgttaac agacatttgt
     3541 actagttttc caactaatgt agaatcttgt cctcctgaaa tacctaacac taaagatttt
     3601 ataaatgaat gtgattgtac ataatttttt ataaattgct ttaattccat aatttcttca
     3661 gcactatcga tacgcttttt cactttcatt tcttgtacaa taacgtcttg taatttactc
     3721 attatcttct tccatctcct taacgtgttc cgcaacttca aaaatacgtt tatgtttatt
     3781 atcccaacat gccttgctta aatcgactgg atattcttgt ggattaagga aacgcttatt
     3841 ttcatcccaa atagattgta atccttgtgc taaatattca cgtgattcat cttctgttgg
     3901 catttgatat actaatttac cattttcata aatattatga tgcaaatcaa tggcttcgaa
     3961 agattttata aatttcattt tataagtatg cactggatgg aataatttta aaggttgttc
     4021 atcgtatgga ttttcatttt ccaaagtaat ataatcgcct tctgccttac ctgttttctt
     4081 gtttataatg cgatatacat ttttcttacc tggcgtcgta accttttcag cgttatttga
     4141 taatttaata cgatcactat atgaaccctc ttcattttca atagctacaa gtttatatac
     4201 tgcacctaat gctggttgat cgtatcctgt aatcagcttt gtaccaacgc cccaagaatc
     4261 tacttttgca ccttgtgctt tcaaactcgt aatcgtttct tcatccaaat cattagacgc
     4321 gataatttta gtttcagtaa atcctgcttc atcaagcata cgtcttgcct ctttagataa
     4381 ataagcgata tctccagaat ccaatcgaat acctacaaag ttaattttgt cacctaattc
     4441 ttttgcaact tttattgcat ttggcacgcc agattttaaa gtatggaatg tatctactag
     4501 gaacacacaa tttttatgtc tttcagcata ttttttgaag gcaacatatt catctccata
     4561 agtttggaca aatgcgtgtg catgtgtacc agacacaggt ataccaaata atttacctgc
     4621 cctaacatta cttgtagaat caaagccccc gatgtaagca gctctagcgc cccacaatgc
     4681 tgcatcaatt tcttgcgcac gacgtgtacc aaactccatt aatttatcat ttgatgcaat
     4741 ttgacgaatt ctactagcct ttgttgtaat tagtgtatgg aaatttacaa tgtttaataa
     4801 aattgtttct attaattgcg cttgaatcaa tggtgcttct acgcgtaaca atggttcgtt
     4861 accaaagcat aattcgcctt cttgcatcga acgaatgctt cctgtgaatt ttaaatcttt
     4921 taaatatgat aagaaatcat ccttgtagcc aatagacttt aaatattcca aatcagattc
     4981 tgaaaatcca aaatgttcta taaaatcaat gacgcgtttt aaaccattaa aaacagcata
     5041 gccactatta aatggcattt ttctaaaata caaatcaaat acagccattt tttcatgaat
     5101 attatcattc caataacttt cagccatatt tatttgatat aagtcattat gtaacattaa
     5161 actgtcgtct tctaattggt acacttgtat ctctccaatc gacctaaata ttttcttaca
     5221 ttttatcata attcattttt ttatatacat aagagcccct taatttccat acttttaatt
     5281 aaaatcaacc aacaatttaa tgacatatac ataattttta agagtatttt aataatgtag
     5341 actataatat aaagcgaggt gttgttaatg ttatttaaag aggctcaagc tttcatagaa
     5401 aacatgtata aagagtgtca ttatgaaacg caaattatca ataaacgttt acatgacatt
     5461 gaactagaaa taaaagaaac tgggacatat acacatacag aagaagaact tatttatggt
     5521 gctaaaatgg cttggcgtaa ttcaaatcgt tgcattggtc gtttattttg ggattcgtta
     5581 aatgtcattg atgcaagaga tgttactgac gaagcatcgt tcttatcatc aattacttat
     5641 catattacac aggctacaaa tgaaggtaaa ttaaagccgt atattactat atatgctcca
     5701 aaggatggac ctaaaatttt caacaatcaa ttaattcgct atgctggcta tgacaattgt
     5761 ggtgatcctg ctgaaaaaga agttacacgc ttagcaaatc acttaggttg gaaaggaaaa
     5821 ggtactaatt ttgacgtgtt accactgatt taccaattac ctaatgagtc agttaaattt
     5881 tacgaatatc ctacttcatt aattaaagaa gtacctattg aacataatca ttatccaaaa
     5941 ttaagaaaat tgaacttaaa atggtatgca gtccctatca tttccaatat ggacttaaaa
     6001 atcggtggca ttgtatatcc aactgcaccc tttaacggtt ggtatatggt aactgaaatt
     6061 ggcgtacgta actttattga tgattaccgt tacaatttac tagaaaaagt tgcagatgcg
     6121 tttgaatttg atacacttaa aaataattca tttaataaag atcgagcact tgttgaattg
     6181 aactatgctg tgtatcattc ctttaaaaaa gaaggcgtat caattgtcga tcatttgacc
     6241 gctgcaaagc aattcgaact attcgaacgt aacgaagcac aacaaggtcg tcaagttacc
     6301 ggaaaatggt cttggctagc accgccatta tctccaacat tgacgtcaaa ttatcatcac
     6361 ggatatgaca atacagtaaa agatccaaac tttttctata aaaagaaaga atcaaatgct
     6421 aaccagtgcc ctttccatca ttaagttagt agaggtgtag catatgcaat tatattattt
     6481 aggccctaaa ggtacatttt catatttggc ttgtcgtcag tatttttctg aaaatgaagc
     6541 aacttttcaa ccaaagtcaa atttatttga agtcatcaag gcagttgcag atgatgacac
     6601 atcgattggt gttgtcccta ttgaaaattc tatagaagga acaatcaaca ttgtggcaga
     6661 tgcacttgca cagcaagatg tctttgcaca cggtgaaata cgtttagata ttaactttgc
     6721 attatatggt aatggaacag attccatttc tgatattaaa aaagtgtatt ctattgcacc
     6781 agcaatcagt caaacaacaa attacataca tcaacatcaa tttgactatg attatgtcga
     6841 cagtacaatt caaagtttga ctaaaattga aaatggcgtt gcagcaattg cacctttagg
     6901 tagtggcgaa gcttatggtt ttacacctat tgatacacat attgaagact atccacataa
     6961 cgtgacacgt tttttagtta taaaaaatca gcagcaattt gatcaaaatg cgacatcatt
     7021 gatgttttta attacaccaa tgcatgataa acctgggctg ttagcaagtg tgcttaatac
     7081 atttgctttg tttaatatta atttatcctg gattgagtct cgtcctttaa aaacacaatt
     7141 aggtatgtat cgatttttcg ttcaggctga ttctgcaatt acaaccgata taaagaaagt
     7201 cattgctatt ttagaaacct tagatttcaa agtagaaatg attggtgctt ttaattaaac
     7261 tttattttct aggttctaca atttaaataa aataaagagt caaccaagga ttaaaatagg
     7321 aatccatcct tggttgactt tcttttgttt gtattgtttt tacacgatgc tgcggtatac
     7381 gtttcattac cactcgttca agcaattgct aatgtaacct tttatttttc gttctaatct
     7441 gcaattacta tttcaatggc agtggttgat ttatatcaat acctaaaact ataggcatta
     7501 cataatacac gactaaaata ataattattg cactgattaa gtttacccag aatcctactg
     7561 atgccatttg tttgatagat attttacctg aaccaaagat aattgcattc ggtggtgtcc
     7621 ctactggtaa catgtatgca cagttagccg ccatagctgc aggtgccata agtagtaatg
     7681 gatgcactcc aacagcaaca gacaacgttg ctaaaatcgg taaaatcatc gttgcagttg
     7741 cagtattaga tgtcacttca gttaaaaata agacaaagat tgttatgaca attacaataa
     7801 gaatcggact aacaccattt aatgatttca actgttcgcc taaccatttt gctaaaccac
     7861 tttcagaaat acctttcgct aatgctaaac cgccaccaaa taaaattaat acaccccaag
     7921 ggagctcttt tgcaacttcc cagtcaatga tacggcgatg tttttcagta tttttagctg
     7981 gaataataaa taataatatt gatataaaaa tagcaatcgt accatctgca acagatgacg
     8041 taacttccca ttttttcaga agaaactctc ttgtaatcca taataagctg gcaagtacaa
     8101 agatagtttg tactaccttt tcttcatact tcattttgcc aagctcgtct aacttttgtt
     8161 taattaacgt ctgaccacca ggtaaatatt tcaaatcatg tctaaacgca acatatctta
     8221 aatagagcca agtaatacct aacaaaacaa tgaccgttgg aatccctaca atcatccatt
     8281 tagcaaaact aatttcatgt ccaaaatgtt gcatgtattg tccttttaaa ataattaatg
     8341 gcggggttcc gattaatgta cccaagccac caatcgtacc tgcatagcca attgctaaaa
     8401 ctagagattt ttcaaacttt tgaatacttg tttgattcgt attggcttct tgtaaatcat
     8461 gtgcttcctt aataattgct aaaccaatcg gaatcataat cattacagct gcagtgttcg
     8521 atacaaacat agataagaat cctgttgcca ccatgaatcc aagtaatatt tttgaagtgc
     8581 ttgcaccaat taaattaata atagtcaaag ctactctcgt atgtaaattc catctttcca
     8641 ttgcaattgc caaaataaat ccacctaaaa acaaaaagat aatatcattg ccatattcgg
     8701 atgatacttg ttctggtgta agtatgtgac ctaatggtaa taacacaatt ggtaataagc
     8761 tcgttgctgc aataggaatt gcttcagtaa tccaccaagt cgcaatccat aaagtaatcg
     8821 ctaagacata tacgcctttc caaggtaagt cttgtggatg aaagaacaat aatgttaata
     8881 ggaaaagtaa tggacctaat attagtccaa taagttgtcc cgcactaaac ggtttctttt
     8941 tctttgattt tgaaaagaat gttaaatacc ttttcgatat cattgattga tgttgattga
     9001 aataagccat aaatttcccc ctcatgatga ttatgacaag ctacttcaac tcactatatt
     9061 agagtataga aagttgtcta tcttgtatta tcattaccgt caaaataccc cttttatcag
     9121 ataattgggt ttattatagc atatttatac cgttttatga atgcgctttc aaaaattatc
     9181 tactattctt aatcctaatg tcatgcgaaa ctttttactt ttttatttca tctatattga
     9241 ttgtagtaac ttgaataccc gcttcaacag gacttaaaaa cactgtatca atatcttcta
     9301 aatgaattga ttgagtcgaa ttattgaatg tattcccaac gattaataca tctttatgtt
     9361 taacattatt ataattacgt acatgtatcg catctttaga cattgatcct ttaaattcat
     9421 ttccaattat attcatattt atgcctgctt gggaacctaa gtcttttcct gtcatcacat
     9481 ctgctgcatt tttaccatct ctaactccta aatatctaat accaccctca cagttaataa
     9541 acttattatt aataatgaaa gcatctttat acttcaaggg agttaatgca taaccttgta
     9601 tatcttcaaa tatattattt ctaatatgaa tattctcata gtaacgatta tgtctacttg
     9661 catgtgagcc aatagcacga ttccaacttc ccatttcggg caattctgaa ggtccaaaat
     9721 aacaatcttc gataacgaca tttttcgtta tcgtaccatc tgtcgttccg aattttggaa
     9781 aagcaccagg tacttgaatg tctaattgta ttgcttcaga ataaaagcgt tcgccactat
     9841 agtctatgaa tccttcaaat gaacagcttt taatatagag tccgttaatc ccacaagcat
     9901 caattgcatg accactcact acattcttaa tggtcacacc tattaattga atatcttcag
     9961 catgcccaat gcacatagct gtattgttat aaggatacga tacaccattc atatcaaact
    10021 tgccgccttt aatatgaata tgactgtgtc cattataacc acgataaaaa ccaaagcgat
    10081 gaccattttt taataaagga ccagaatgac atcggcgtaa aatagtttca ttatctaaca
    10141 aaagtgttgt attgccatat atcgttaatg gtttgcaaat atcatacgtc cctttcggta
    10201 tataaactgt cgttggttta catcttccac gatttaacgc acgttgtatt gctcgagtat
    10261 ctttagtttt gtttatgcct gttaacccat aatctttcat attgatatac ataaatcgtc
    10321 atcctttgtc tattttctaa ttactcatat attaaccaat tattcaaatt ataatcgtgt
    10381 taggttgatt tagcagatag tcataaatct cgtgatgcca tctattagca tttttatatt
    10441 caaaacatca acacttgata ttagttctaa gtttgtcaca tttagtattc tattacagct
    10501 attttaaaac tatcgcaaaa acttcttata ttatttgttg attgcgtgat ttgctcttcc
    10561 aaaaaagttg attaatctat atacttaatc tatatttata tattaaccat tagggttaaa
    10621 aattactcta gcatttatga atagatggga gtttatttta ttatatagga gagatgttga
    10681 atgacacatc gcgcactatt agttgttgac tattcatatg actttatcgc agatgacggc
    10741 ttactaacat gcggtaaacc tggacaaaat attgaagatt ttattgtttc tcgtatcaat
    10801 gactttaatt attatcaaga ccatatattc tttttaatgg atttacatta tttacatgac
    10861 attcatcatc ctgaaagtaa attattccca ccacacaata tcgtagatac aagtggtaga
    10921 gaattatacg gtaaagtagg taaattatac gaaacaatta aagcgcaacc taatgtacat
    10981 ttcattgata aaacgcgcta tgattcgttc tttggtaccc cgcttgatag tttattgaga
    11041 gaaagaagta ttaatcaagt cgaaatcgtt ggtgtatgta ccgatatttg cgtgttacat
    11101 acagcaattt ctgcatacaa cttaggttat aaaatttcag tacctgctga gggagtggct
    11161 tcatttaatc aaaaagggca tgaatgggca cttgcacatt tcaaaaactc attaggtgca
    11221 gaggtagaac aacacgttta aatcgtgcta aaataattat aaagaataca atttacaagg
    11281 gagatatttg acaatggcta aaacatatat tttcggacat aagaatccag acactgatgc
    11341 aatttcatct gcgattatta tggcagaatt tgaacaactt agaggtaatt caggagccaa
    11401 agcataccgt ttaggtgatg tgagtgcaga aactcaattc gcgttagata catttaatgt
    11461 acctgctccg gaattattaa cggatgattt agatggtcaa gatgttatct tagttgatca
    11521 taacgaattc caacaaagtt ctgatacgat tgcctctgct acaattaagc atgtaattga
    11581 tcatcacaga attgcaaatt tcgaaactgc tggcccttta tgttatcgtg ctgaaccagt
    11641 tggttgtaca gctacaattt tatacaaaat gtttagagaa cgtggctttg aaattaaacc
    11701 tgaaattgcc ggtttaatgt tatcagcaat tatctcagat agcttacttt tcaaatcacc
    11761 aacatgtaca caacaagacg ttaaagcagc tgaagaatta aaagatattg ctaaagttga
    11821 tattcaaaag tacggcttag atatgttaaa agcaggtgct tcaacaactg ataaatcagt
    11881 tgaattctta ttaaacatgg atgctaaatc atttactatg ggtgactatg tgactcgtat
    11941 tgcacaagtt aatgctgttg accttgacga agtgttaaat cgtaaagaag atttagaaaa
    12001 agaaatgtta gctgtaagtg cacaagaaaa atatgactta tttgtacttg ttgttactga
    12061 catcattaat agtgattcta aaattttagt tgtaggtgct gaaaaagata aagtcggcga
    12121 agcattcaat gttcaattag aagatgacat ggccttctta tctggtgttg tttctcgaaa
    12181 aaaacaaatc gtacctcaaa tcactgaagc attaacaaaa taatactata ttactgtcta
    12241 atcatagaca tgttgtattt aactaacagt tcattaaagt agaatttatt tcactttcaa
    12301 tgaactgttt tttatttacg tttgactaat ttacaacctt ttcaatagta gttttcattc
    12361 ctttagctat cctaacccac agattagtga tttctataca attcctcttt tgtctttaca
    12421 ttttcttaaa atatttgcga tgttgagtat aaatttttgt tttcttccta cctttttcgt
    12481 tatgattaaa gttataaata ttattatgta cacgattcat cgctctattt tcaactttca
    12541 acatatataa ttcgaaagac catttaaaat taacggccac aacaatcaaa tcaattaatc
    12601 actttttcca aaataatcat ataaggaggt tcttttcatt atgaatatca ttgagcaaaa
    12661 attttatgac agtaaagctt ttttcaatac acaacaaact aaagatatta gttttagaaa
    12721 agatcaatta aagaagttaa gcaaagctat taaatcatac gagagcgata ttttagaagc
    12781 actatataca gatttaggaa aaaataaagt cgaagcttat gctactgaaa ttggcataac
    12841 tttgaaaagt atcaaaaatg cccgtaagga acttaaaaac tggactaaaa caaaaaatgt
    12901 agacacacct ttatatttat ttccaacaaa aagctatatc aaaaaagaac cttatggaac
    12961 agttttgatc attgcaccat ttaactatcc ttttcaacta gtattcgaac ctttaatcgg
    13021 tgctattgca gcaggtaata cagcaattat taaaccatct gagttgacac caaatgttgc
    13081 acgagtgatt aaacgattaa tcaatgaaac atttgatgca aattacattg aagttattga
    13141 gggaggaatt gaagaaacgc aaacgttaat tcacttacct tttgactatg tcttctttac
    13201 aggaagtgaa aatgtaggca aaatcgttta tcaagctgcc agcgaaaatt tagttcctgt
    13261 gacattagaa atgggtggta aatctccagt catcgttgat gaaacagcga atattaaagt
    13321 tgctagtgag cgcatttgtt ttgggaaatt cactaatgcc ggccaaacat gtgttgcacc
    13381 agattacatt ttagtacacg aatctgtaaa agatgattta atcacagccc tatcaaaaac
    13441 gttgcgtgaa ttttatggtc aaaatataca acaaagtcca gattatggcc gcattgtaaa
    13501 ccttaaacat tatcatcgtc tgacttcatt acttaacagt gcacaaatga atattgtatt
    13561 tggtggtcat agtgatgagg atgaacgtta tatagaacca acattgttag atcacgttac
    13621 aagtgattca gcaattatgc aagaagaaat ttttggtcct atcttaccga ttttaacgta
    13681 tcagtcattg gatgaagcaa tagcctttat tcaccaaaga ccaaaacctt tgagtttata
    13741 tttatttagc gaagatgaaa atgctacaca acgtgtaata aacgagttat catttggcgg
    13801 cggcgctatt aatgatacat tgatgcacct agcgaatcct aaattaccat ttggtggtgt
    13861 tggcgcctca ggtatgggac gctatcatgg taaatattca ttcgacactt ttacacatga
    13921 aaaaagctac attttcaaat ctacacgatt agaatcaggt gtccatttac caccatataa
    13981 aggtaaattt aaatacatca aagctttctt taaaaattaa tttttgagac aaaaataaac
    14041 catgcttcca taatttgatg ttcttgaaaa caataaattt caaggtatac acaaattttt
    14101 tgtaaacatg gttttctttt tatcatgatt aattaaagat taaaatatga cacatacacc
    14161 ttcagatgct acacgagtat tatcacatag agtaatttta cctgtttctt tacttctttc
    14221 aaaaacagtt acaactgaat ctccttgctc atgagcacaa actaaaaggt catctgatga
    14281 ggcaatatta aaatctcttg ggaattgacc accactttca gtaattgtta ctagttctaa
    14341 gtgttgacca ttatcaagaa ctttaaaaat tgcaatgcta tcatgccctc tattagatac
    14401 atataagaat tgttgatcat gagacaaacg cactgctgca agtttagtat ctccatcaaa
    14461 gttttcagga attgttaaat gacgctcgag ctcttcaaat ttaccgtcat tatattctgc
    14521 aacactcaca gtatttgata attcgtgtac gacataagca aattttccat tatcatgaaa
    14581 ttcaatatgt cttgtcccat cactatcttt aaataaagat tctttataaa attcaaaccc
    14641 gttgtcatca aatttataag taacgatacg atcagcacct aaatctgtta ctgcaacgta
    14701 cttaccatct ggagtttgat taatataatg tgcgtgtgga tgatcttgtc tttcatgtgt
    14761 acctgttgga aaatcatgtg caagttcttg aattagacgt ataatttcac ctgtgtgcgt
    14821 atttaattca tacatacgta tgatgccagc accatatacc gcttcaaata aatatcgttt
    14881 atcttctgaa atcgatacat aacaacctgt accagctttt gaagacaaac atttatttaa
    14941 taaatgcaat tcaccattgt catcaatttt caaactcgca acaccgcatt gttctccttc
    15001 tttgttgatt ccatataaaa cttcgttatt acgcaccaaa tatgtagacg cttctaattc
    15061 aaatcctatt tctaataaat caatacgtga ctgattttcg tttaattcaa aacgataaat
    15121 ccctttacca ttctttttag tgtaagaacc aatatatcca tttgtcatta cttttacccc
    15181 tccatgtcag tcttattttc attttattaa attttagcta gaattaacaa tcatttatca
    15241 tttccttaac gctaaaactg tttaactact ttaaaagaac tatttgctgt gatatgtcat
    15301 tattcgattt taattaatcc ctctttttta cttacacgag cattaattat taacgcgttt
    15361 atgcttccac aaaatttttg ttgcaaaaca gaacacatgt tcgtataatg taattatcag
    15421 attggggtga attaaggatg acaagttatg aagaagaaac tgattatcgt aacgttccaa
    15481 gagaattact agataacaat atacctatgg gaagaggcat gattaaatgg gctccttttg
    15541 caacattacc cgaacaattc gaaacgattc aacaatacat tatcgaccaa aacaaaatta
    15601 cacgtcctgt attatcagat gatcaattgg ctgagctaaa cattcggcta cacgaggcgc
    15661 tacaatatgc ccaacctgta gaagttaaat tttataataa tggctttgta gattcagtac
    15721 gcttaaccat ttatcgtatt gatgctatta attatgaaat tgatggttat gtttacaatc
    15781 agcaacaacg tcaaaaaatt tctatctttg atatcttaga tattgtcttg ttaccttaat
    15841 gctttgaaca taattaaaca gattgagtat atgcatataa gatgattttt aacatcattt
    15901 ttggatgata ggatgttgcg ccacgatgat gtctgaattc atcgaattcg ctatcaggta
    15961 ttgtttcaac aatttcatta acatatcgtg aaatatcatt ttgagggatt ctaacagaag
    16021 tttctattgg tagtgtagtt gggtcatgtt ataattttta tacataaggc acctcgttaa
    16081 tttagtttag tggtatttat taaattataa gaagggaccc aacacagaaa attcatttta
    16141 ttgaatttta catttatgtg caagttgggc aaagtgtctt attttttaaa agtatttcaa
    16201 agtaaaatta catgttaata cgtagtatta atggcgagac tcctgaggga gcagtgccag
    16261 tcgaagacc
//
LOCUS       DAPDIM010000059        15906 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000059 DAPDIM010000000
VERSION     DAPDIM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 15906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15906
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.059"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            95..1051
                     /locus_tag="RFE25_002136"
     CDS             95..1051
                     /locus_tag="RFE25_002136"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDU2817174.1"
                     /translation="MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLS
                     KGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYNGP
                     DMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKD
                     GNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQL
                     YQRSADIFLGVPFNIASYALLTHLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLA
                     RESFNPPTLKINSDKSIFDINYEDLEIVDYESHPAIKAPIAV"
     gene            1251..1730
                     /locus_tag="RFE25_002137"
     CDS             1251..1730
                     /locus_tag="RFE25_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDU2817175.1"
                     /translation="MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMG
                     RKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEM
                     IDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK"
     gene            1745..2584
                     /gene="fakB2"
                     /locus_tag="RFE25_002138"
     CDS             1745..2584
                     /gene="fakB2"
                     /locus_tag="RFE25_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid kinase binding subunit FakB2"
                     /protein_id="HDU2817176.1"
                     /translation="MTKQIIVTDSTSDLSKEYLEVNNIHVIPLSLTIEGASYVDQVDI
                     TSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQA
                     SQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIG
                     QLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEF
                     IGDHEIKSIGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVV
                     LKK"
     gene            2670..3203
                     /gene="msrA"
                     /locus_tag="RFE25_002139"
     CDS             2670..3203
                     /gene="msrA"
                     /locus_tag="RFE25_002139"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDU2817177.1"
                     /translation="MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHVDNPTYE
                     QVCTNKTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYH
                     DEHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQR
                     GSGRKAFIESHWGNQNA"
     gene            3196..3624
                     /gene="msrB"
                     /locus_tag="RFE25_002140"
     CDS             3196..3624
                     /gene="msrB"
                     /locus_tag="RFE25_002140"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDU2817178.1"
                     /translation="MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKIS
                     GKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMVRTEVRSEESNSHLGHVFN
                     DGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK"
     gene            3636..4136
                     /locus_tag="RFE25_002141"
     CDS             3636..4136
                     /locus_tag="RFE25_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDU2817179.1"
                     /translation="MFKKLFGKGKEVQKDIAIYAPLTGEYVKIEDIPDPVFAQKMMGE
                     GFGINPTEGEVVSPIAGRVDNVFPTKHAIGLKADNGLELLVHIGLDTVQLDGEGFEVL
                     VSSGDEVNVGDPLVRFNLEFINNNAKSVISPIIITNTDQAASINIYDENAVIKGETKV
                     IDVTMN"
     gene            4136..4357
                     /locus_tag="RFE25_002142"
     CDS             4136..4357
                     /locus_tag="RFE25_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDU2817180.1"
                     /translation="MKNYSFYQFVMTVRGRHDDKGRLAEEIFDDLAFPKHDDDFNILS
                     DYIETHGDFTLPMSVFDDLYEEYTEWLKF"
     gene            4549..6039
                     /locus_tag="RFE25_002143"
     CDS             4549..6039
                     /locus_tag="RFE25_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDU2817181.1"
                     /translation="MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILI
                     GTTLITAVITVVAYIFINQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKA
                     AIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
                     ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREK
                     IHVKSVEYKKKGKVGVITINKFQNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLD
                     EAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDSLKEAKDMDISILVNEGSASASEVF
                     TGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPD
                     VTIDTPKYQSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQV
                     KAFQQANKLEVTGEFNKETNNKFTELLVEKANKHDDVLDKLINILK"
     gene            6439..6948
                     /locus_tag="RFE25_002144"
     CDS             6439..6948
                     /locus_tag="RFE25_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2817182.1"
                     /translation="MIRLGKMSDLDQILNLVEEAKELMKEHDNEQWDDQYPLLEHFEE
                     DIAKDYLYVLEENDKIYGFIVVDQDQAEWYDDIDWPVNREGAFVIHRLTGSKEYKGAA
                     TELFNYVIDVVKARGAEVILTDTFALNKPAQGLFAKFGFHKVGEQLMEYPPYDKGEPF
                     YAYYKNLKE"
     gene            6960..8030
                     /locus_tag="RFE25_002145"
     CDS             6960..8030
                     /locus_tag="RFE25_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDU2817183.1"
                     /translation="MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIERE
                     MIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGG
                     FVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADF
                     IGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQ
                     VIHLTGKGLKDAQVKKSGYIQYEFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPM
                     LLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQELNEMEQERTRIINNM
                     KSYEQSYTKEALFDKMIKDALN"
     gene            8047..8661
                     /locus_tag="RFE25_002146"
     CDS             8047..8661
                     /locus_tag="RFE25_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDU2817184.1"
                     /translation="MSQWKRISLLIVFALVFGIIAFFHESRLGKWIDNEVYEFIYSSE
                     SFITTSIMLGATKVGEVWAMLCISLLLVAYLMLKRHKIEALFFALTMALSGILNPALK
                     NIFDRERPTLLRLIDITGFSFPSGHAMGSTAYFGSGIYLLNRLNQGNSKGILIGLCAA
                     MILLISISRVYLGVHYPTDIIAGIIGGVFCIILSTLLLRNKLIN"
     gene            8778..8978
                     /locus_tag="RFE25_002147"
     CDS             8778..8978
                     /locus_tag="RFE25_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817185.1"
                     /translation="MTNPTRTKRCGGDVLCGIDNHFQLLLYISENHCQLETKTFFEYF
                     LRIVNKTHDYAILENKKICISH"
     gene            9055..9187
                     /locus_tag="RFE25_002148"
                     /pseudo
     CDS             9055..9187
                     /locus_tag="RFE25_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499947.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9449..10108
                     /gene="arlR"
                     /locus_tag="RFE25_002149"
     CDS             9449..10108
                     /gene="arlR"
                     /locus_tag="RFE25_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor ArlR"
                     /protein_id="HDU2817186.1"
                     /translation="MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSH
                     YYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITAKSDTYDKVAGLDYGADDYIVKP
                     FDIEELLARIRAILRRQPQKDIIDVNGITIDKNAFKVTVNGAEIELTKTEYDLLYLLA
                     ENKNHVMQREQILNHVWGYNSEVETNVVDVYIRYLRNKLKPYDRDKMIETVRGVGYVI
                     R"
     gene            10105..11460
                     /gene="arlS"
                     /locus_tag="RFE25_002150"
     CDS             10105..11460
                     /gene="arlS"
                     /locus_tag="RFE25_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase ArlS"
                     /protein_id="HDU2817187.1"
                     /translation="MTKRKLRNNWIIVTTMITFVTIFLFCLIIIFFLKDTLHNSELDD
                     AERSSSDINNLFHSKPVKDISALDLNASLGNFQEIIIYDEHNNKLFETSNDNTVRVEP
                     GYEHRYFDRVIKKRYKGIEYLIIKEPITTQDFKGYSLLIHSLENYDNIVKSLYIIALA
                     FGVIATIITATISYVFSTQITKPLVSLSNKMIEIRRDGFQNKLQLNTNYEEIDNLANT
                     FNEMMSQIEESFNQQRQFVEDASHELRTPLQIIQGHLNLIQRWGKKDPAVLEESLNIS
                     IEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDEIRSRIHSLKQLHPDYQFDTDL
                     TSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKKIKVKTRLKNKQKIIEITDHGIGIP
                     EEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQLNGGSIKIKSEINKGTTFKII
                     F"
     gene            11744..14542
                     /locus_tag="RFE25_002151"
     CDS             11744..14542
                     /locus_tag="RFE25_002151"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HDU2817188.1"
                     /translation="MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLF
                     STIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPK
                     LEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNT
                     ERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALV
                     PMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPED
                     GSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDD
                     TQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIG
                     FTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDL
                     VGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEMHSFIEQVQ
                     KELRQAHDKINKADKMDNPDMEKPAELALPLQADEQSFTFDHLKEINDALLTYPDGFN
                     ILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHR
                     HAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEA
                     QYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAA
                     ENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSG
                     GFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIE
                     ALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDG
                     EIHKLVQNKIIENALKNN"
     gene            14556..15824
                     /gene="sucB"
                     /locus_tag="RFE25_002152"
     CDS             14556..15824
                     /gene="sucB"
                     /locus_tag="RFE25_002152"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HDU2817189.1"
                     /translation="MPEVKVPELAESITEGTIAEWLKNVGDSVEKGEAILELETDKVN
                     VEVVSEEAGVLSEQLASEGDTVEVGQAIAIIGEGSGNASKENSNDNTPQQNEETNNKK
                     EETTNNSVDKAEVNQANDDNQQRINATPSARRYARENGVNLAEVSPKTNDVVRKEDID
                     KKQQAPASTQTTQQAPAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLLEVSNNTAMLT
                     TFNEVDMTNVMELRKRKKEQFMKDHDGTKLGFMSFFTKASVAALKKYPEVNAEIDGDD
                     MITKQYYDIGVAVSTDDGLLVPFVRDCDKKNFAEIEAEIANLAVKAREKKLGLDDMVN
                     GSFTITNGGIFGSMMSTPIINGNQAAILGMHSIITRPIAIDQDTIENRPMMYIALSYD
                     HRIIDGKEAVGFLKTIKELIENPEDLLLES"
BASE COUNT         5970 a         2237 c         2868 g         4831 t
ORIGIN      
        1 cctaaaatga gtgataacaa aatgctacat aaaattaagt tatatcaaac taaatataca
       61 tactataaat aatgaaaatg aggtgttatc gcatatgttg aattcatttg atgcagcata
      121 tcacagtctt tgtgaagagg ttttagaaat aggaaataca cgaaatgatc gcacaaatac
      181 aggtacgatt tcgaaatttg gtcatcaact tcgctttgac ttatctaaag gatttccact
      241 attaacgaca aagaaagttt cttttaaatt agtagcaacc gaattattat ggttcattaa
      301 aggagataca aacatccaat acttattaaa atataataat aatatttgga acgaatgggc
      361 ttttgaaaat tatataaaat cagacgagta taacggtcca gatatgacag atttcgggca
      421 tcgtgcattg agtgatcctg aatttaacga acaatataaa gaacaaatga aacaatttaa
      481 gcaacgtatt cttgaagatg atacttttgc gaagcaattc ggtgatttag gaaatgttta
      541 tggtaaacaa tggcgagatt gggttgataa agatggtaat cattttgatc aacttaaaac
      601 agtaattgaa caaattaagc ataatccaga ttcaagacga cacatcgtat ctgcatggaa
      661 tccaacagaa attgatacaa tggcacttcc gccttgtcat accatgttcc agttttatgt
      721 ccaagatggt aagttaagtt gccagttata ccaacgtagc gcagatatct ttttaggtgt
      781 gccatttaat atcgcaagct acgctttatt gacacacctt attgccaaag aatgtggact
      841 tgaagtagga gaatttgtgc atacatttgg agatgcacat atttattcaa atcatattga
      901 tgcgattcaa acacaattag cacgtgaaag cttcaatcct ccaacattaa aaattaacag
      961 tgacaagtct attttcgaca taaattatga agatttggaa attgttgact atgaatcaca
     1021 tccagcaata aaagctccaa tagcagtgta gtcattgcat agttagctaa ccatatagac
     1081 atcaaaatga catcatagta ttttcaagtg caaaaaagta cttttttgtg ttaaacgttt
     1141 tcataaatta tgcaaaatca ttatttctat cacactttat gataaaaatt gtgttaaatt
     1201 aaagataact tagtaataaa aaatgaaatg atagaagaag gaggataatt atgactttat
     1261 ccattctagt tgcacatgac ttgcaacgag taattggttt tgaaaatcaa ttaccttggc
     1321 acctaccaaa tgatttgaaa catgttaaaa aattatcaac aggtcatact ttagtaatgg
     1381 gtcgtaagac atttgaatcg attggtaaac cactaccgaa tcgtcgaaat gttgtactta
     1441 cttcagatac aagtttcaac gtagagggcg ttgatgtaat tcactctatt gaagatattt
     1501 accaactacc gggccatgtt ttcatatttg gagggcaaac attatttgaa gaaatgattg
     1561 ataaagtgga cgacatgtat attactgtta ttgaaggtaa attccgtggt gatacgttct
     1621 ttccacctta tacatttgaa gactgggaag ttgcctcttc agttgaaggt aaactagatg
     1681 agaaaaatac aattccacat acctttctac atttaattcg taaaaaataa gggggaaaac
     1741 gaccatgaca aaacagatta tagtaacaga ctcaacatcc gatttatcta aagaatactt
     1801 agaagtaaac aacattcatg taattccttt aagtttaact attgaaggag cttcatacgt
     1861 tgaccaagta gatattacat cagaagaatt tattaatcat attgaaaatg atgaagatgt
     1921 aaagacaagt cagccagcca taggtgaatt tatatctgct tatgaagaac taggaaaaga
     1981 tggctctgaa atcataagta ttcatctttc ttcaggatta agtggtacat ataacactgc
     2041 ttaccaagca agtcaaatgg tagatgctaa tgtaactgtt attgattcaa aatctatttc
     2101 ttttggttta gggtatcaaa tacaacacct agtagagctt gtaaaagaag gtgtctcaac
     2161 ttctgaaata gttaaaaagt taaatcattt aagagaaaac attaaattat ttgtagttat
     2221 agggcaattg aatcaattaa ttaaaggtgg cagaattagt aaaacaaaag gtttgattgg
     2281 taatcttatg aaaattaaac caattggtac acttgatgat ggtcgcttag agcttgtgca
     2341 caatgcgaga actcaaaatt ctagtatcca atacttgaaa aaggaaattg ctgaatttat
     2401 aggagatcat gaaatcaaat ccattggtgt cgcacatgct aacgtcattg aatatgttga
     2461 taaattgaag aaagttttta acgaagcttt tcatgtgaat aattacgata taaatgtaac
     2521 tacaccagtt atttctgcac atactggtca aggtgcgatt ggcctcgtag tccttaagaa
     2581 gtaaatttaa tcttttcagt gttaattact tccatttcaa tcctttatag actaaattta
     2641 taattagata gatagaggag gtaattcata tgacaaaaga atatgcaaca ttagcaggag
     2701 gatgtttctg gtgcatggtt aaaccattta catcatatcc aggcatcaag tcagtcgtat
     2761 ctggttatag tggcggtcat gttgataacc ctacttatga acaggtatgt acgaataaaa
     2821 ccggccatgt cgaagcagta caaattacgt ttgatccaga ggttacttcc tttgaaaata
     2881 tattagacat atatttcaaa acatttgacc caactgatga tcaagggcaa tttttcgata
     2941 gaggcgaaag ctatcaacca gtcattttct atcatgatga gcatcagaaa aaggctgctg
     3001 agtttaaaaa gcaacaatta aatgaacaag gtattttcaa gaaaccagtg attacaccta
     3061 ttaaaccata taaaaatttc tatccagctg aagactacca tcaagattat tataaaaaga
     3121 acccggtaca ttattaccaa tatcaacgtg gttcaggtag aaaagcgttt atagaatcac
     3181 attgggggaa tcaaaatgct taaaaaagat aaaagtgaac taacagacat agaatatatt
     3241 gttacacaag aaaatggcac tgaaccacca tttatgaatg aatattggaa tcattttgct
     3301 aaagggattt atgtagataa gatttctggt aaacctttat ttacatctga agaaaagttt
     3361 cattctgaat gtggatggcc tagcttttct aaagcgcttg atgacgatga aattatagaa
     3421 ttagtcgaca aatcatttgg tatggtaaga actgaagtgc gttcagaaga atcaaatagt
     3481 catttaggac acgtctttaa tgatggacct aaagaaagtg gcggcttaag atactgtatc
     3541 aattccgctg caattcaatt tattccatat gaaaaattag aagaattggg ttatggcgat
     3601 ttaatatcac attttgataa gtaggagtgg aaagtatgtt taaaaaatta ttcggaaaag
     3661 gcaaagaagt tcagaaagat atcgcaattt atgcaccatt aactggagaa tacgtgaaaa
     3721 ttgaagatat tccagatcct gtattcgcac aaaaaatgat gggcgaaggt tttggtatta
     3781 atccaactga aggagaagtt gtgtctccaa ttgcaggacg tgttgacaat gtctttccaa
     3841 ctaagcatgc gattgggtta aaagcagata acggattaga attattagtt catatcggtt
     3901 tagacacagt tcaattagac ggtgaaggat ttgaagtgtt agtgtctagt ggtgacgaag
     3961 ttaacgtcgg agatccatta gtaagattca accttgaatt tattaataat aacgctaaat
     4021 ctgttatttc accaattata attactaaca ctgatcaagc agcttcaatt aatatttatg
     4081 atgaaaatgc tgtgattaaa ggtgaaacaa aagtgattga tgtgacaatg aactaatgaa
     4141 aaactattcg ttttatcaat ttgtcatgac agttcgtggt cgacacgacg ataaaggtcg
     4201 tctagcagaa gagatatttg acgatcttgc tttcccaaaa cacgatgatg attttaacat
     4261 actgtctgat tatattgaga cacatggtga tttcacattg ccaatgtctg tatttgatga
     4321 tttatatgaa gaatatacgg aatggctaaa attttaatat aatttttaaa aataatagtt
     4381 agaaccaggg tgatgcaatt cgttatcctg gttttaattt aaaataaact aagttgtgac
     4441 taaaaattaa tcaattatag tgaaatatgg tgcgctatct tgcataaatt gatatgatta
     4501 actacacaga atttaaaagt acataataca taataaggaa gtgatacaat ggatgataag
     4561 caacacacat cttcatccga tgatgaacgc gctgaaattg caacaagcaa tcaagaccaa
     4621 gaaactaatt catcgaaacg cgttcactta aaacgttggc aattcatatc aatattaatt
     4681 ggcacaaccc taataacagc tgtcatcaca gttgttgcat atatttttat aaatcaaaaa
     4741 ataagtggtt taaacaaaac tgatcaagca aacttaaata aaattgaaaa tgtgtataaa
     4801 atcttaaata gtgattatta caaaaaacag gactctgaca agttaagtaa agctgcaatt
     4861 gatggtatgg tcaaagaatt aaaagatcct tattctgaat atttaacaaa agaacaaacg
     4921 aaatccttta atgaaggtgt ttcaggtgat tttgtaggta ttggtgcaga aatgcaaaag
     4981 aaaaatgatc aaattatggt tactagccct atgaagggtt ctccagcaga acgtgctggc
     5041 atccgtccta aagatgtcat tactaaagta aatggaaaat caattaaagg aaaagcatta
     5101 gacgaagttg tcaaagacgt tcgtggtaaa gaaaacactg aagtaacttt aactgttcaa
     5161 cgaggcagtg aagaaaaaga cgttaagatt aaacgtgaaa aaattcatgt taaaagtgtt
     5221 gagtataaga aaaaaggtaa ggttggagtt attactatta ataaattcca gaatgataca
     5281 tcaggtgaat tgaaagatgc agttcttaaa gctcacaaag atggtttgaa aaagattgtt
     5341 ttagatttaa gaaataatcc tggtggacta ctagatgaag ctgttaaaat ggcaaatatt
     5401 tttatcgata aaggaaaaac tgttgttaaa ctagaaaaag gtaaagatac tgaagcaatt
     5461 caaacttcta atgactcgtt aaaagaagcg aaagacatgg atatatccat cttagtgaat
     5521 gaaggttcag ctagtgcttc tgaagtgttt actggtgcgc taaaggacta taataaagct
     5581 aaagtttatg ggtcaaaaac attcggcaaa ggtgtcgtac aaactacaag agagtttaag
     5641 gatggttcat tgttaaaata tactgaaatg aaatggttaa cgccagatgg tcattatatt
     5701 cacggtaagg gcattaaacc agacgttact attgacacac ctaaatatca atctttaaat
     5761 gtcattccta atacgaaaac atttaaagtt ggagacgatg ataaaaatat taaaactatt
     5821 aaaattggtt tatcagcttt aggttataaa gttgataatg aatcaacgca atttgatcaa
     5881 gctttagaaa atcaagttaa agctttccaa caagcgaata aactcgaggt aactggtgaa
     5941 tttaataaag aaacgaataa taaatttact gagttattag ttgaaaaagc taataaacat
     6001 gatgatgttc tcgataagtt gattaatatt ttaaaataag cgatacacac tactaaaatt
     6061 gtattattat tatgttaatg acacgcttcc taaatttgca aagatagcaa tttaggaggc
     6121 gtgtttattt ttattgacgt ctaaccctaa aagatataaa ttagacattt acaaatgatg
     6181 taaataacgc aatttctatc atcgctgtta acaattcatg ctttaatata ctatgagcat
     6241 atacttttta aatagtatta ttcactagtt ttaacaatcg attaattggt atatgatact
     6301 tttattggtt attttcatcc catagtgtga taattactat ttttcattca taataaaggt
     6361 ttaaagcatg ttaatagtgt gtaagattaa catgtactga aaaacatgtt taacataacg
     6421 atataaggag tgacgtacat gatccgtcta ggtaaaatgt cagatttaga tcaaatctta
     6481 aatctagtag aagaagcaaa agaattaatg aaagaacacg acaacgagca atgggacgat
     6541 cagtacccac ttttagaaca ttttgaagaa gatattgcta aagattattt gtacgtatta
     6601 gaggaaaatg acaaaattta tggctttatt gttgtcgacc aagaccaagc agaatggtat
     6661 gatgacattg actggccagt aaatagagaa ggcgcctttg ttattcatcg attaactggt
     6721 tcgaaagaat ataaaggagc tgctacagaa ttattcaatt atgttattga tgtagttaaa
     6781 gcacgtggtg cagaagttat tttaacggac acctttgcgt taaacaaacc tgcacaaggt
     6841 ttatttgcga aatttggatt tcataaggtc ggtgaacaat taatggaata tccgccatat
     6901 gataaaggtg aaccatttta tgcatattat aaaaatttaa aagaatagag gtaatattaa
     6961 tgacgaaaat cgcatttacc ggagggggaa cagttggaca cgtatcagta aatttaagtt
     7021 taattccaac tgcattatca caaggttatg aagcgcttta tattggttct aaaaatggta
     7081 ttgaaagaga aatgattgaa tcacaactac cagaaattaa gtattatcct atttcgagtg
     7141 gtaaattaag aagatatatt tctttagaaa atgccaaaga cgtatttaaa gtattgaaag
     7201 gtattcttga tgctcgtaaa gttttgaaaa aagaaaaacc tgatctatta ttttcaaaag
     7261 gtggatttgt atctgtgcct gttgttattg cagccaaatc attaaatata ccaactatta
     7321 ttcatgaatc tgacttaaca ccaggattag cgaataagat agcacttaaa tttgccaaga
     7381 aaatatatac aacatttgaa gaaacgctaa actacttacc taaagagaaa gctgatttta
     7441 ttggagcaac aattcgagaa gatttaaaaa atggtaatgc acataatggt tatcaattaa
     7501 caggctttaa tgaaaataaa aaagttttac ttgttatggg tggaagctta ggaagtaaaa
     7561 aattaaatag cattattcgc gaaaacttag atgcattatt acaacaatat caagtgatac
     7621 atttaactgg taaaggatta aaagatgctc aagttaaaaa atcaggatat atacaatatg
     7681 aatttgttaa agaggattta acagatttat tagcaattac ggatacagta ataagtagag
     7741 ctggatcaaa tgcgatttat gagttcttaa cattacgtat accaatgtta ttagtaccat
     7801 taggtttaga tcaatcccga ggcgaccaaa ttgacaatgc aaatcatttt gctgataaag
     7861 gttatgctaa aacgattgat gaagaacaat taacagcaca aattttatta caagaactaa
     7921 atgaaatgga acaggaaaga actcgaatta tcaataatat gaaatcgtat gaacaaagtt
     7981 atacgaaaga agctttattt gataagatga ttaaagacgc attgaattaa tggggggtaa
     8041 tgctttatga gtcaatggaa acgtatctct ttgctcatcg tttttgcatt ggtttttgga
     8101 attatcgcgt ttttccacga atcaagacta gggaaatgga ttgataatga agtttatgaa
     8161 tttatatatt catcagagag ctttattacg acatctatca tgcttggggc tactaaagta
     8221 ggtgaagtct gggcaatgtt atgtatttca ttacttcttg tggcatatct catgttaaag
     8281 cgccacaaaa ttgaagcatt attttttgca ttaacaatgg cactatctgg aattttgaat
     8341 ccagcattaa aaaatatatt cgatagagaa agacctacat tgctgcgttt aattgatata
     8401 acaggattta gttttcctag cggtcatgct atgggatcaa ctgcatattt tggaagtggt
     8461 atctatctat taaatcgatt aaatcaaggt aattcaaaag gtattcttat agggttatgt
     8521 gcagctatga ttttattgat ttccatatca cgtgtatatc taggtgtaca ttatccaaca
     8581 gatattattg ccggcattat tggtggcgta ttttgcatta ttttatcaac gttattactt
     8641 agaaataaat taataaatta aatagtaaaa aaacaaaagc agtaaaccta aagtgtcgta
     8701 agggtttact gcttttataa aacgttgtta taacgtatat tgtcttttac gggcatataa
     8761 aaggggaata tttgaaaatg accaatccaa caagaacgaa acgttgtggg ggggatgttc
     8821 tatgtggtat tgataatcat tttcaactac tattatacat tagtgagaat cattgtcaat
     8881 tagaaactaa aacttttttt gaatattttt taagaatagt aaataaaacg catgattacg
     8941 ctattttaga aaataaaaaa atttgtattt ctcattagaa ttagaatatt taaaagttat
     9001 gaggtttaaa aattatattg tttacatact ccttttgaat ttatacatta tgaaatgtta
     9061 cttccaagtt caaaatcgca cattgaaatg atgtgtgaaa atgtttaaac tacggtcatt
     9121 ttgtgaaaat aaagataata actattcatt ttacaatagt gaaaagtcag tatatgacaa
     9181 caattaatat tgcggtaagg ccttgtgtta cagtattcta tatttaagta ctgcaatcag
     9241 aattaacaga atgccattaa ctgattatta aatatttgag ttaataaata attaatgatt
     9301 gtagcttgaa aaatttaaaa catggttatt gatttgtgat aaaatttaaa cgtaaacaaa
     9361 ctaatttaaa aagcaactat tgtatagaaa aatacaaaat ttaaaatata ttaccttatt
     9421 agaaaaagtc gtaatatgag gtgtacaaat gacgcaaatt ttaatagtag aagatgaaca
     9481 aaacttagca agatttcttg aattggaact cacacatgaa aattacaatg tggacacaga
     9541 gtatgatgga caagacggtt tagataaagc gcttagccat tactatgatt taatcatatt
     9601 agatttaatg ttgccgtcaa ttaatggctt agaaatttgt cgcaaaatta gacaacaaca
     9661 atctacacct atcattataa ttacagcgaa aagtgatacg tatgacaaag ttgctgggct
     9721 tgattacggt gcagacgatt atatagttaa gccgtttgat attgaagaac ttttagcaag
     9781 aattcgtgca attttacgtc gtcagccaca aaaggatatt atcgatgtca acggtattac
     9841 aattgataag aacgctttta aagtgacggt aaatggcgca gaaattgaat taacaaaaac
     9901 agagtatgat ttactatatc ttctagctga aaataaaaac catgttatgc aacgggaaca
     9961 aattttaaat catgtatggg gttataatag tgaagtagaa acaaatgtcg tagatgttta
    10021 tataagatat ttacgaaaca agttaaaacc atacgatcgt gacaaaatga ttgaaacagt
    10081 tcgtggcgtt gggtatgtga tacgatgaca aaacgtaaat tgcgcaataa ctggattatt
    10141 gttaccacga tgattacgtt tgtcacgata tttttgtttt gtttaattat tatttttttc
    10201 ttgaaagata cactgcataa tagtgagctt gatgatgcag aacgaagctc aagcgatatt
    10261 aataatttat ttcattctaa gcctgttaaa gatatatctg cattagactt gaatgcatct
    10321 ttaggtaatt ttcaagagat aattatttat gatgagcata ataataaatt atttgagaca
    10381 tcgaatgata acacagtgag agttgaacca ggttatgaac accgttattt tgaccgcgta
    10441 ataaaaaaac gctataaagg cattgaatat ttaattatta aagaaccaat tacaacgcaa
    10501 gatttcaaag ggtatagctt gttaattcat tcactagaaa attatgataa catcgtaaaa
    10561 tcattgtata tcattgcgct ggcatttgga gtgattgcaa caattataac tgccacaatc
    10621 agttatgtat tttcaacaca aattactaaa ccgcttgtca gtttatcaaa taaaatgatt
    10681 gagattcgac gagatggttt tcaaaataaa ttgcaattaa atacaaatta tgaagaaata
    10741 gataatttag caaatacgtt taatgagatg atgagccaaa ttgaagaatc atttaatcaa
    10801 caaagacaat ttgttgaaga tgcgtcacat gaattacgaa caccattaca aattattcaa
    10861 ggtcatttaa atttgattca gcgatgggga aaaaaagacc cagcagtatt agaagaatcg
    10921 ttaaatattt ctattgaaga aatgaatcgt atcataaaat tagtcgaaga attacttgaa
    10981 ttgactaaag gagatgtaaa tgacatttct tctgaagcgc agaccgtgca tattaatgat
    11041 gaaattcgct cgcgaataca ctcattaaaa caattgcatc ctgattatca atttgatacg
    11101 gatctgacat ctaaaaatct agaaattaaa atgaaacctc atcaattcga acaattattt
    11161 ttaatcttta ttgataatgc aatcaaatat gatgtgaaga ataagaaaat taaagttaag
    11221 acaaggttaa aaaataagca aaaaataatt gaaattacag atcatggaat tggtattcca
    11281 gaggaagatc aagatttcat ttttgatcgc ttttatcgag tggataaatc tcgttcaaga
    11341 agtcaaggcg gtaatggact cggattatct attgctcaaa aaatcattca attaaacgga
    11401 ggatcgatta aaattaaaag tgaaattaat aaaggaacaa cgtttaaaat catattttaa
    11461 tcatgtctga gacgtcaatc aaagtcatag gatcaatttt ttaagtacac attagctgtg
    11521 actaatgtat aagaacaact ataaaacaaa taaacagtgg ttctttatca tttctgttgt
    11581 actcccaaaa tttacaataa aatacatcta taaacctaga agaatcaacg cttttgttga
    11641 ttcttctttt tagcagataa ataggtaaat ctactttaac aaataactaa atagtgatat
    11701 tattacattg taagcgtttc aacatttttg tggagggtgt aaaatgacta acgaaagaaa
    11761 agaagtttca gaggctcctg taaacttcgg tgcgaattta ggtctaatgt tagatctata
    11821 tgatgacttt ttacaagatc catcatctgt accagaagat ttacaagtct tattcagcac
    11881 aattaagaat gatgactcaa ttgtaccagc tttaaaaagt acaagtagtc aaaatagcga
    11941 cggcacaatt aagcgtgtca tgcgtctaat tgataatatt cgccaatacg ggcatcttaa
    12001 agccgatatt tatcctgtaa atcctccaaa aaggaaacat gtacctaaat tagagattga
    12061 agactttgat ttagatcaac agactttgga aggtatatca gcaggaattg tttcagatca
    12121 ctttgccgac atttatgata atgcttatga agcaatttta agaatggaaa aacgttacaa
    12181 aggaccaatt gcatttgagt atacacatat taataacaat accgaacgtg gttggttaaa
    12241 aagaagaatt gaaacgccat ataaagtaac gttaaataat aacgaaaaaa gggcactatt
    12301 caaacaatta gcgtatgttg aagggtttga aaaatatctt cataaaaact tcgttggtgc
    12361 aaagcgtttt tcaattgaag gggtagacgc acttgtaccg atgttacaac gtactattac
    12421 gattgctgcg aaagaaggta ttaaaaatat acaaataggc atggctcacc gtggacgttt
    12481 aaacgtttta acgcatgtct tagaaaaacc gtacgaaatg atgatttcag aatttatgca
    12541 tacagatcca atgaaattct tacctgaaga tggtagcttg cagttaactg ctggatggac
    12601 tggtgatgtg aaatatcacc ttggtggcat taaaactact gattcatacg gtacaatgca
    12661 gcgtattgca ctggctaaca atccaagtca cttggaaatt gttgcacctg ttgttgaggg
    12721 gcgtacgaga gcagcacaag atgatacaca acgagctggg gctccgacga ctgatcatca
    12781 taaagcaatg ccaattatta tacatggcga tgctgcttat cctggtcaag gaattaactt
    12841 cgaaacaatg aacttaggaa acttgaaagg ctattctacg ggtggttcat tgcatattat
    12901 tactaacaat agaattggat ttactacaga accaattgat gcacgttcaa caacttattc
    12961 tacagatgtg gccaaaggtt atgatgtgcc aatattccat gtcaatgctg atgacgttga
    13021 agctactatt gaagcaattg atattgcaat ggaatttaga aaagagtttc ataaagacgt
    13081 cgttattgat ttagtaggtt atcgtcgttt cggacataac gaaatggatg aaccatcaat
    13141 tactaatcca gttccttatc agaatattcg caaacatgac tctgttgaat atgtgtttgg
    13201 taaaaagctt gttaatgaag gtgtcatttc agaagatgaa atgcattcat ttatagaaca
    13261 agtccaaaag gaactaagac aagctcatga taaaattaat aaagctgata aaatggataa
    13321 tccagatatg gaaaaacctg cagaacttgc attaccgtta caagcagacg aacaatcatt
    13381 tacgtttgat catttgaaag aaataaatga tgcattgtta acatatccgg atggctttaa
    13441 cattttgaaa aagttaaaca aagttcttga gaagcgtcat gagccgttta ataaagaaga
    13501 tggcttagtt gattgggcac aagcagaaca acttgcattt gcgacaattt tacaagatgg
    13561 tacaccgatt cgcttaactg gtcaagatag tgaacgtggt acattcagtc ataggcatgc
    13621 cgtgttacat gatgagcaaa caggtgaaac atatacacct ttacatcatg ttcctgatca
    13681 aaaagcgaca tttgatatac acaattctcc gctttcagaa gcagcagtag ttggttttga
    13741 atacggctat aatgtggaaa acaaaaaaag cttcaatatt tgggaagcgc aatatggtga
    13801 ttttgcaaat atgtcacaaa tgatttttga caacttctta ttcagttctc gctcaaaatg
    13861 gggagaacgt tcaggattaa cattattctt acctcatgca tatgagggtc aaggacctga
    13921 acattcatca gcaagattag agcgattttt acaattagct gctgaaaata attgcacagt
    13981 tgtcaactta tctagttcaa gtaattattt ccacttattg cgtgcacaag cagctagttt
    14041 agattctgaa caaatgcgac cattggttgt tatgtcacca aaaagcttat tgagaaataa
    14101 aacagttgcc aaaccaattg atgagtttac ttctggtgga tttgagccaa ttttgacaga
    14161 atcatatcaa gcggataagg ttacaaaagt tattttagca actggtaaaa tgttcattga
    14221 tttaaaagaa gcattagcta aaaatccaga cgaatccgtg ttactcgttg cgattgaaag
    14281 attgtatcca ttcccagagg aagagattga agcattacta gcacaattgc caaaccttga
    14341 agaagtgtca tgggtacaag aagaacctaa aaatcaaggt gcatggttat atgtctatcc
    14401 atatgttaaa gtgctagttg cagataaata tgatttaagt tatcatggca gaattcaaag
    14461 ggctgctcca gctgaaggcg atggagaaat tcataaactt gttcaaaata aaattataga
    14521 aaatgcatta aaaaataact agggggaaat aagtcatgcc agaggttaaa gttccagaat
    14581 tagcagaatc tattacagaa ggtaccattg cagaatggtt gaaaaacgta ggggatagcg
    14641 tagaaaaagg tgaagctatt cttgaattag aaactgataa agttaatgtc gaagttgtat
    14701 ctgaagaagc aggtgtatta tctgaacaac ttgcaagtga aggcgacact gtagaagttg
    14761 gacaagcaat tgctatcatc ggcgaaggta gtggcaatgc ttctaaagaa aatagtaacg
    14821 acaatactcc acaacaaaat gaagaaacaa ataataaaaa agaagaaaca acaaataatt
    14881 cggtagataa agctgaagtc aatcaagcaa atgatgacaa tcagcaacgt attaatgcta
    14941 cgccttctgc gcgtcgatat gctcgtgaaa atggtgtgaa tcttgctgaa gtaagtccga
    15001 aaacaaatga tgtggttcgt aaagaagata ttgataagaa acaacaggca ccggcatcaa
    15061 cacaaacaac acaacaagca cctgcaaaag aagagaaaaa atacaatcaa tatcctacaa
    15121 aaccagtgat tcgtgaaaaa atgtcacgca gaaagaaaac agctgccaaa aaattattag
    15181 aggtatctaa taatacagct atgttaacaa catttaacga agttgacatg acaaatgtta
    15241 tggaattgcg taaacgtaag aaagaacaat ttatgaaaga tcatgatggt actaaattag
    15301 gatttatgtc attctttact aaagcttctg tagcagcttt gaaaaagtat ccagaagtta
    15361 atgcagaaat cgatggcgac gacatgatta cgaaacaata ttatgatatt ggtgtagctg
    15421 tttctacaga tgatggatta ttagtaccat ttgtaagaga ttgtgataaa aagaattttg
    15481 cagaaatcga agcagaaatt gctaatttag cagttaaagc acgagagaaa aaacttggct
    15541 tagatgatat ggttaatggt tcatttacga ttacaaatgg cggtattttt ggatcaatga
    15601 tgagtacgcc aattatcaat ggtaatcaag ctgcaatctt aggcatgcat tcaattatta
    15661 caagaccaat tgcgattgat caagatacaa tcgaaaatcg tccaatgatg tatattgcat
    15721 taagctatga tcatagaatt attgacggta aagaagcagt tggattctta aaaacaatta
    15781 aagaattaat tgaaaaccca gaagacttat tattagaatc ttaatccaca acacaaaata
    15841 gtttactatt cctaaaaacg taatcaaatc aataacaaac agcagtaaga ttattttcta
    15901 gtcgaa
//
LOCUS       DAPDIM010000060        15233 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000060 DAPDIM010000000
VERSION     DAPDIM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 15233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15233
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.060"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            76..393
                     /locus_tag="RFE25_002153"
     CDS             76..393
                     /locus_tag="RFE25_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5011 domain-containing protein"
                     /protein_id="HDU2817190.1"
                     /translation="MNKLLQSLSALGVSATLVTPNLNADATTNTTPQIKGANDIVIKK
                     GQDYNLLNGISAFDKEDGDLTDKIKVDGQIDTSKSGKYQIKYHVTDSDGAIKISTRYI
                     EVK"
     gene            complement(534..659)
                     /locus_tag="RFE25_002154"
     CDS             complement(534..659)
                     /locus_tag="RFE25_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817191.1"
                     /translation="MERKRKHFKKEFAKSNLSLNNEKWKFVCSKSKHFLKRAVKF"
     gene            964..2064
                     /gene="qoxA"
                     /locus_tag="RFE25_002155"
     CDS             964..2064
                     /gene="qoxA"
                     /locus_tag="RFE25_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit II"
                     /protein_id="HDU2817192.1"
                     /translation="MSKFKSLLLLFGTLILLSGCSNIEIFNAKGPVASSQKFLILYSI
                     VFMLVICFVVLGMFAIFIYKYSYNKNAESGKMHHNAIIETIWFVIPIIIVAALAIPTV
                     KTLYDYEKPPKSEKDPMVVYAVSAGYKWFFAYPDEHIETVNTLTIPKDRPVVFKLQAM
                     DTMTSFWIPQLGGQKYAMTGMTMNWTLEASQTGTFRGRNSNFNGEGFSRQTFKVNAVS
                     QKDYDKWVKEVKGKKTLDQDTFDKQLLPSTPNKALEFNGTHMAFVDPAADPEYIFYAY
                     KRFNFELKDPNFTSEENMFKDVSDKPLIPARKAQITNANYKRHGMKLMILGNDEPYNN
                     EFKKDESKNAKEMKKISKDAQDQDNDDHGGGH"
     gene            2064..4052
                     /gene="qoxB"
                     /locus_tag="RFE25_002156"
     CDS             2064..4052
                     /gene="qoxB"
                     /locus_tag="RFE25_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit I"
                     /protein_id="HDU2817193.1"
                     /translation="MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLY
                     KEWFTSVDHKKIGIMYLICAVLMFVRGGIDALLIRAQLTVPDNKFLESNHYNEIFSTH
                     GVIMIIFMAMPFIFGLWNIVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGG
                     SPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFM
                     QMPMFTVTTFITTLIVILAFPPLTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWV
                     WGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAFLSFLVWVHHFFTMG
                     NGALINSFFSISTMLIGIPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVT
                     GVMLAMASADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKW
                     CFWFFMIGFNVCFLPQFILGLDGMPRRLYTYMPSDGWFLLNLISTIGALLMAIGFLFL
                     VVSIVYSHFKSPREATGDNWDGLGRTLEWTTASAIPPKYNFAITPDWNDYDTFVDMKE
                     HGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGGFFLIFETVIPALICLFGIFGTMIY
                     RSFQIDHGYHIPAAEVAETEARLREARIKEREAVSHES"
     gene            4042..4647
                     /gene="qoxC"
                     /locus_tag="RFE25_002157"
     CDS             4042..4647
                     /gene="qoxC"
                     /locus_tag="RFE25_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit III"
                     /protein_id="HDU2817194.1"
                     /translation="MSHDTNTIDSRTHEGELNKLGFWIFITAEFALFGTLFATLLTLQ
                     HGGDYAGKMTTELFELPLVLIMTFALLFSSYTCGIAIYYMRQEKQKLMMFWMIITLLL
                     GLVFVGFEIYEFAHYASEGVNPTIGSYWSSFFILLGTHGCHVSLGIVWAICLLIQIQR
                     RGLDKYNAPKLFIVSLYWHFLDVVWVFIFTAVYMIGMVYSG"
     gene            4656..4934
                     /gene="qoxD"
                     /locus_tag="RFE25_002158"
     CDS             4656..4934
                     /gene="qoxD"
                     /locus_tag="RFE25_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit IV"
                     /protein_id="HDU2817195.1"
                     /translation="MKHTVGFIASIVLTLLAVYVTLYTSLTFHAKLTIIFGFAFVQAG
                     LQLLMFMHLTEGKDGRLQTFKVIFALVITLCFVVGTYWVMQGGHSSHL"
     gene            complement(5471..6664)
                     /gene="fmtA"
                     /locus_tag="RFE25_002159"
     CDS             complement(5471..6664)
                     /gene="fmtA"
                     /locus_tag="RFE25_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala esterase FmtA"
                     /protein_id="HDU2817196.1"
                     /translation="MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETK
                     LSDNEKYLVDRNKEKVAPSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKM
                     SKGYGYQDFEKGIKNTPNTMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFK
                     TSKPIPLKDLMLHQSGLYKYKSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLV
                     LAKVIEEVTGKSYAENYYTKIGDPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRP
                     NILDQYYGAGNLYMTPTDMGKLITQIQQYKLFSPKITNPLLHEFGTKQYPDEYRYGFY
                     AKPTLNRLNGGFFGQVFTVYYNDKYVVVLALNVKGNNEVRIKHIYNDILKQNKPYNTK
                     GVIVQ"
     gene            7115..8332
                     /locus_tag="RFE25_002160"
     CDS             7115..8332
                     /locus_tag="RFE25_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase"
                     /protein_id="HDU2817197.1"
                     /translation="MNKFLKYFLILLALVLIVVPIVFATLLFKTSQDAFESSQDSKNA
                     NRQSNLRDNKVNPEEQPISILFLGIDDNDGRRKKGQDAEHSRSDAMILTTFNQSKHQI
                     RMLSIPRDTISYIPKVGYYDKITHAHAYGGPIAAMDSVEATMNVPVDYYVRVNMKAFV
                     EAVNELGGIYYDVPYDLNEPNTDDTGKIKIKKGYQKLNGDEALAVARTRHHDSDLKRG
                     QRQMELIKILFQKAQEVDSIDKLDNVIQIVGKNAKHNLTNSEIKALAKMYLTNDVEIK
                     TAQLKGKDDMLNGIYYYHPSVESIQKYANLLRKDLELSPINDKNDFLDQRVINHYGSL
                     IPLTPLDSSLLRKEQNDTTDKDKTSNENNDSTNNSDSSNQQQPATDQNLNQNQGGTQQ
                     APQASNNQNGVVN"
     gene            8380..8850
                     /locus_tag="RFE25_002161"
     CDS             8380..8850
                     /locus_tag="RFE25_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499548.1"
                     /note="Essential protein for resistance to osmotic stress
                     from salt; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic stress response protein"
                     /protein_id="HDU2817198.1"
                     /translation="MSRKTYEKIANINGMFNMLEQQIIHSQDMAHFRSEFFYVNHEHR
                     ENYEALLIYYKNSIDNPIVDGACYILALPEIFNSVDVFESELPFSWVYDENGITETMK
                     SLSIPLQYLVAAALEVTDVNIFKPSGFTMGMNNWNIAQMRIFWQYTAIIRKEAL"
     gene            9005..9439
                     /locus_tag="RFE25_002162"
     CDS             9005..9439
                     /locus_tag="RFE25_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2817199.1"
                     /translation="MFSKVNNQKMLEDCFYIRKKVFVEEQGVPEESEIDEYESESIHL
                     IGYDNGQPVATARIRPINETTVKIERVAVMKSHRGQGMGRMLMQAVESLAKDEGFYVA
                     TMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIEMTKKLTSLN"
     gene            9667..13413
                     /locus_tag="RFE25_002163"
     CDS             9667..13413
                     /locus_tag="RFE25_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional autolysin"
                     /protein_id="HDU2817200.1"
                     /translation="MAKKFNYKLPSMVALTLVGSAVTAHQVQAAETTQDQTTNKNVLD
                     SNKVKATTEQAKAEVKNPTQNISGTQVYQDPAIVQPKTANNKTGNAQVSQKVDTAQVN
                     GDTRANQSATTNNTQPVAKSTSTTAPKTNTNVTNAGYSLVDDEDDNSEHQINPELIKS
                     AAKPAALETQYKAAAPKAKTEATPKVTTFSASAQPRSVAATPKTSLPKYKPQVNSSIN
                     DYIRKNNLKAPKIEEDYTSYFPKYAYRNGVGRPEGIVVHDTANDRSTINGEISYMKNN
                     YQNAFVHAFVDGDRIIETAPTDYLSWGVGAVGNPRFINVEIVHTHDYASFARSMNNYA
                     DYAATQLQYYGLKPDSAEYDGNGTVWTHYAVSKYLGGTDHADPHGYLRSHNYSYDQLY
                     DLINEKYLIKMGKVAPWGTQFTTTPTTPSKPTTPSKPSTGKLTVAANNGVAQIKPTNS
                     GLYTTVYDKTGKATNEVQKTFAVSKTATLGNQKFYLVQDYNSGNKFGWVKEGDVVYNT
                     AKSPVNVNQSYSIKSGTKLYTVPWGTSKQVAGSVSGSGNQTFKASKQQQIDKSIYLYG
                     SVNGKSGWVSKAYLVDTAKPTPTPIPKPSTPTTNNKLTVSSLNGVAQINAKNNGLFTT
                     VYDKTGKPTKEVQKTFAVTKEASLGGNKFYLVKDYNSPTLIGWVKQGDVIYNNAKSPV
                     NVMQTYTVKPGTKLYSVPWGTYKQEAGAVSGTGNQTFKATKQQQIDKSIYLFGTVNGK
                     SGWVSKAYLAVPAAPKKAVAQPKTAVKAYTVTKPQTTQTVSKIAQVKPNNTGIRASVY
                     EKTAKNGAKYADRTFYVTKERAHGNETYVLLNNTSHNIPLGWFNVKDLNVQNLGKEVK
                     TTQKYTVNKSNNGLSMVPWGTKNQVILTGNNIAQGTFNATKQVSVGKDVYLYGTINNR
                     TGWVNAKDLTAPTAVKPTTSAAKDYNYTYVIKNGNGYYYVTPNSDTAKYSLKAFNEQP
                     FAVVKEQVINGQTWYYGKLSNGKLAWIKSTDLAKELIKYNQTGMTLNQVAQIQAGLQY
                     KPQVQRVPGKWTDANFNDVKHAMDTKRLAQDPALKYQFLRLDQPQNISIDKINQFLKG
                     KGVLENQGAAFNKAAQMYGINEVYLISHALLETGNGTSQLAKGADVVNNKVVTNSNTK
                     YHNVFGIAAYDNDPLREGIKYAKQAGWDTVSKAIVGGAKFIGNSYVKAGQNTLYKMRW
                     NPAHPGTHQYATDVDWANINAKIIKGYYDKIGEVGKYFDIPQYK"
     gene            complement(13483..13593)
                     /locus_tag="RFE25_002164"
     CDS             complement(13483..13593)
                     /locus_tag="RFE25_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817201.1"
                     /translation="MSLCTQQKLNHELQAKVAVIVKIDGKQSPLFLLVYV"
     gene            complement(13620..14039)
                     /locus_tag="RFE25_002165"
     CDS             complement(13620..14039)
                     /locus_tag="RFE25_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDU2817202.1"
                     /translation="MYKQLEKLITLTNNDLNLVNRRFGQRTDITSEQLELLRILFNYD
                     RLSQYDLTMKISREQSIVSRWIKKLVLKGYITSQQSSEDLRCKELILTDQARTLISQI
                     NNARCELIEARCQCLSEVELDNLNQLLDKLNQRRISL"
     gene            14192..15202
                     /locus_tag="RFE25_002166"
     CDS             14192..15202
                     /locus_tag="RFE25_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HDU2817203.1"
                     /translation="MTSLKERDYFFDNARAILILLVVFGHMLQPYTSGDKYLSALYLV
                     IYSFHMPTFLFISGYFAKNIDKPYYLEKISKRLIVPYMIFFAFFSIYYFLTGKSDELQ
                     LDPFNPVFALWFLITLFFFHVILVIVRRFNPYKVLSVSIIISIGAGFSDNIDSYLSIS
                     RTIVFFPIFYLGYIFTKKHTAIFKNKKLIPVSIITFILFFIIYVIHPINADWLLGSSP
                     YTSLENEGQSIFSPFKRLILYGIILIAMTAFLNLMSTKKKLYTYIGSRTLYVYLLHGL
                     IIGIVRGFEWYPFDNPISLMTYLYLISISVIIVYVLSTNFVCKWTNPIINLQRPSQFK
                     DS"
BASE COUNT         5291 a         2524 c         2383 g         5035 t
ORIGIN      
        1 tatgatgtgt aaataatata aattaaggta tagtaaagct aactcagaaa tgacttatca
       61 ttcggaggtt acattatgaa taaactatta cagtcattat cagccctcgg tgtttctgct
      121 acactagtaa caccaaattt aaatgcagat gcaacgacga atactacacc acaaattaaa
      181 ggcgctaatg atatcgttat taagaaaggt caagattata accttctaaa cggcataagt
      241 gcatttgata aagaagatgg agatttaacc gataaaatta aagtcgatgg ccaaattgat
      301 acatctaaat ctggtaaata tcaaattaaa tatcatgtca ctgattcaga tggtgcaatt
      361 aaaatttcca ctaggtatat tgaggttaaa tagccctcat cactatactg taaataaaat
      421 ggtagcaaac gaacatgttt tgctaccatt ttatttgtta ttccaacttc atctgcaact
      481 ttaacctaaa tattgtattt tttctgtata ccaaaggact acctatcaaa ttattaaaac
      541 ttaactgctc tttttaaaaa atgttttgat tttgaacaaa caaatttcca cttttcattg
      601 tttaacgata aattactttt ggcaaattcc tttttaaagt gtttgcgctt cctttcaatg
      661 aactagccat cattttcaat ttattagaca atttcaaact ttttttattt tcattcaatt
      721 aacctttaat tgaaagctat tctcaacttt ccttttaaat atgaagcaat tttttcaaaa
      781 acgctattag tcacaaaatg tacacataat tttaacaaat gtgtgaaccc acgtcacacc
      841 ttgatttatc aacatttttg atacaatttt attaattttt ttcccataag cccttgtaaa
      901 tattgtgtaa taacttaaaa ttaatgttaa gccctacatt tgtagtatta ggaggtcaaa
      961 aaagtgtcaa aatttaagtc tttgcttcta ttatttggca cactaatttt acttagtggt
     1021 tgttcaaata tagaaatttt caacgcaaaa gggccagtag caagtagtca gaagttcttg
     1081 attctttatt caatcgtctt catgcttgtt atttgtttcg ttgtacttgg catgttcgcc
     1141 atttttattt acaagtatag ttataataag aatgccgaat ctggtaagat gcaccataat
     1201 gccatcattg aaacaatatg gtttgtaata cctatcataa tcgttgctgc tttagctatt
     1261 cctacagtta aaactttata cgattacgaa aaaccaccga agagtgagaa agatccaatg
     1321 gttgtatatg cagtaagtgc aggatacaaa tggttctttg cttatccaga tgaacatata
     1381 gagactgtta atacattaac aatccctaaa gatcgtcctg tcgtatttaa gcttcaagct
     1441 atggatacaa tgacaagttt ctggattcca caattaggtg gtcaaaaata tgccatgact
     1501 ggcatgacaa tgaattggac gttagaagca tctcaaactg gtacgttcag aggtcgtaac
     1561 tctaacttca atggtgaagg attctcacgt caaacattta aagtaaatgc cgttagtcaa
     1621 aaagactacg acaaatgggt gaaagaagtt aaaggtaaga aaacgttaga tcaagataca
     1681 tttgataaac aattattacc aagcacacct aataaagctt tagaatttaa tggtacacat
     1741 atggcgtttg ttgatccagc agccgatcca gaatacatct tctatgcata taaacgtttc
     1801 aatttcgaat tgaaagatcc aaacttcact agtgaagaaa atatgtttaa agatgtatca
     1861 gacaaaccat taatacctgc tcgtaaagct caaattacaa atgcgaacta taaacgacat
     1921 ggtatgaagt tgatgattct tggaaatgac gaaccatata acaatgagtt caagaaagat
     1981 gaatcgaaaa atgcgaaaga aatgaagaaa atttcaaaag atgcgcaaga tcaagacaat
     2041 gatgatcatg gaggtggaca ttaatgaatt ttccatggga tcaattacta gttaaaggta
     2101 actggatgat tacaatggca caaattggtg ccccattctt agttattggt ttaatcgcag
     2161 taattactta ctttaaatta tggaaatatc tttacaaaga atggttcaca tctgtagacc
     2221 ataagaaaat cggtattatg tatttaatct gtgccgtatt aatgttcgtc cgtggtggta
     2281 ttgatgcgtt acttattcgt gcgcaattaa cagtacctga taacaaattt ttagaatcta
     2341 accactataa cgaaattttt agtacacatg gtgtaatcat gattatcttc atggcaatgc
     2401 catttatctt tggtttatgg aatatcgttg ttccattaca aattggagca cgtgatgttg
     2461 cattcccagt attaaacaac gtaagtttct ggctattctt tgcaggtatg attttattca
     2521 acctgtcatt tattattggt ggttcaccag cagctggttg gacaaactat gcgccactag
     2581 caggtgaatt cagtcctggt ccgggtgtta actattactt aatagctata caaatttcag
     2641 ggcttggtac cttagctaca ggtatcaact tctttgtaac aattttaaga tgtaaaacac
     2701 caactatgaa gtttatgcaa atgccaatgt ttacagtaac aacatttatt actacattaa
     2761 ttgttattct tgctttccct cctttaacag tagcgttagc attaatgaca actgatagaa
     2821 tatttgacac agcattcttc acagttgcac atggcggtat gccaatgctt tgggctaact
     2881 tcttctgggt atgggggcac cctgaagttt atatcgttat ccttccagca tttggtattt
     2941 actcagaaat tatcccgaca ttcgctcgta agcgtttatt cggacatcaa agtatggtat
     3001 gggcaactgc cggtatcgcg ttccttagtt tcttagtttg ggttcaccat ttcttcacaa
     3061 tgggtaatgg tgcgttaatc aactcattct tctcaatttc aacaatgctg attggtattc
     3121 caactggtgt gaaattgttt aactggttat taacattata taaaggacgt attacatttg
     3181 agtcaccaat gctattctca ttagcattta tccctaactt ccttttaggt ggtgttacgg
     3241 gtgtaatgtt agcaatggca tcagctgact atcaatatca caatacgtac ttcttagtag
     3301 ctcacttcca ctatacattg gttactggtg ttgtatttgc ctgcttagct ggtttaatct
     3361 tctggtatcc aaagatgatg ggttacaaat taaacgaaac attaaacaaa tggtgcttct
     3421 ggttcttcat gatcggattt aacgtttgtt tcttaccaca attcattctt ggattagatg
     3481 gtatgccacg tcgtttatac acttatatgc catcagatgg ttggttctta ttaaacttaa
     3541 tttcaactat cggtgcatta ttaatggcaa tcggattctt attccttgtt gttagtatcg
     3601 tatacagtca cttcaaatct ccacgtgaag caactggaga taactgggat ggccttggcc
     3661 gtactctaga gtggactact gcatcagcaa ttccacctaa atacaacttt gccattacac
     3721 cagattggaa tgactacgac acatttgttg atatgaaaga acatggtcgt cattacttag
     3781 acaaccataa ttacaaagac attcatatgc caaacaatac tcctgttgga ttctggattg
     3841 gtatctttat gactatcggc ggtttcttct taattttcga aactgtaatt ccagcattaa
     3901 tttgtttatt cggtattttt ggtactatga tttatcgcag tttccaaatc gatcacggat
     3961 atcatatccc tgctgctgaa gttgctgaaa ctgaagctag attaagagaa gcgcgtatta
     4021 aagaaaggga ggctgtaagt catgagtcat gatacaaaca ctattgattc acgcacacat
     4081 gaaggcgaat taaataagct tggcttttgg attttcatta cagccgaatt tgcgttattc
     4141 ggtaccctat ttgcgacact attaactttg caacatggtg gcgattatgc aggtaaaatg
     4201 actactgagt tatttgaatt gcctcttgtt ttaataatga cgtttgcatt attattcagt
     4261 tcttacacat gtggtattgc tatttactac atgcgccaag aaaaacaaaa gttaatgatg
     4321 ttttggatga tcattacgtt acttttaggt ttagtctttg ttggattcga aatttatgaa
     4381 ttcgcacact atgcatcaga aggcgttaac ccaacaattg gttcttactg gtctagtttc
     4441 tttatcctat taggaacgca tggttgtcac gtatcgctag gtatcgtttg ggccatttgt
     4501 ttattaatcc aaatccaacg acgcggatta gacaaatata atgcgccaaa attatttata
     4561 gtaagtttat actggcactt cttagatgtt gtttgggttt tcatctttac tgccgtatat
     4621 atgataggga tggtgtatag cggatgagta caataatgaa acatactgta ggatttatcg
     4681 catctatcgt attaacgctt ttagcagttt acgtaacact atacacgtca ttaacattcc
     4741 acgcgaagtt gacaattatc tttggctttg cattcgtcca agcaggactt caattattaa
     4801 tgttcatgca tttaactgaa ggtaaagatg gacgtttaca aacattcaaa gttatctttg
     4861 ctcttgtaat tacactttgt ttcgttgtcg gaacatattg ggttatgcaa ggcggtcact
     4921 cttcacactt ataaacaaca ttttaataat gtaaagttta accagctaac acttttgtta
     4981 gctggttttt attttccttc aatttttaaa tggttaagtc cccttctata tcttataaga
     5041 caatcattat aatcaattca attaatacat taacaaccac aactaataaa tatagtaact
     5101 tcaaaatcca tatttatgtc taaagataat ctcaatgttg ttcacgtcaa taaaattatc
     5161 cctaggtttt taaaaattgt acatgtttaa acaatcaaaa gtgtacatta ttaaattatc
     5221 atttccagtt agatttagaa aacattcaca ccacgcatgg accaacgtat tcgtcttcat
     5281 tcattttagt ctgatgccaa ctcaccaaat gatttcccct tttatcagtt aacacatatt
     5341 tttaaactca tccttcttca accttatact ttaaactttt taccactata aaaaaaaaga
     5401 tataactcgt atactggtca gataaggtcg atgccttaat gccatataca tgttatatct
     5461 tctatattaa ttattgaaca ataacaccct tcgtattgta aggtttattt tgttttaaaa
     5521 tatcattata aatatgtttg attcgaactt cattgtttcc ttttacattt aatgcaagta
     5581 caactacata cttatcatta tagtaaacag taaagacttg tccaaagaat cccccgttaa
     5641 gtctattcaa tgttggctta gcatagaaac catatcgata ttcatctgga tactgtttcg
     5701 taccaaactc atgtaataat ggattggtta ttttaggact gaataattta tattgttgta
     5761 tttgagtaat taatttaccc atatctgttg gtgtcatata taaattacct gcaccatagt
     5821 attggtccaa aatattaggt cttaagaatg aaagtcctgt actattataa gcataacctt
     5881 ttgctagata ttttttaaaa ggttgttcat cataaaatgc tgtgtgctga agttttaaag
     5941 gatctcctat ttttgtataa taattctcag cataagattt acctgtaact tcttcaataa
     6001 ctttcgcaag tactaaataa ttcccatcgt tatacatatg ctttttgtat ttcttaggat
     6061 caataccacg tttttgaatc gctttaactg cttgatctaa atttttataa tcttttgagg
     6121 atttatattt atataatcca ctttgatgca acattaaatc tttcaatggg ataggcttag
     6181 atgttttaaa ccatggaagg tatttactta ctggatcatt gatatttatt ttatgttctt
     6241 cttctaactg ttttaacagt aaccctgttg aaaatttttg agctgaacct attaaaaaca
     6301 tcgtattcgg tgtgttttta ataccttttt caaaatcttg atatccataa cctttactca
     6361 ttttcaattt gccattttca tatatagcta ctgaaccgtt aaataatgaa ctttgtaaat
     6421 acttgtcaat tttcttatat ttaggatcct tgctattata tacctctttt agtttagacg
     6481 gcgcaacctt ttccttatta cgatccacta aatatttttc attgtctgat aattttgttt
     6541 ccttatgtat tgggtctata gaatgtgtct tcgtctgtaa tcgatgaaaa attaacgcta
     6601 tagaaataat gataaataat agtacacacg catgtataac tagttttact ttattaaatt
     6661 tcatttgata attgcctcac aatgtattca ttttatatat ttaaatcgtt aaaaatttga
     6721 acctagatgc ctaataatac aacttacaaa aattaactta tcattcattt atgctttacg
     6781 ctacatagta ataagttttt ctaatatgtt atctatacaa caaaattaat tataccttat
     6841 cactttgtat aaatcactcg aatttatatt acgcctttaa attttttaag acatcatact
     6901 aaagtcgcat tatattttta aaaatgcttt ttgattttaa caaaacattc aaattacaag
     6961 gaactttgac ataacatttg tattttttac tataaagtac tacaatttaa ggctataatg
     7021 tattagtaat gaagttgtat aaatatcgtt caactaatta tattttaaaa ttatgattat
     7081 gatttaacaa aaatttaata taggagcatc aatcatgaat aaatttttaa aatacttttt
     7141 gatccttcta gcattggttc tcattgttgt tccaatagtc ttcgctacgt tactttttaa
     7201 aacgtcccaa gatgcattcg aatcttctca agacagcaaa aatgctaatc gtcaatccaa
     7261 cttaagagat aataaagtca atcccgaaga acaacctatc tctattcttt tcttaggtat
     7321 cgatgataac gatggaagaa gaaaaaaagg acaggatgct gaacactcta gatcagacgc
     7381 tatgatttta actactttta atcaatcaaa acatcaaatt agaatgctta gtattccacg
     7441 tgatactatc agctacattc ctaaagttgg ctattacgat aagattaccc atgcacatgc
     7501 atatggtggt ccaattgccg caatggattc ggtagaagct accatgaatg tacctgttga
     7561 ttattatgtg agagtcaata tgaaagcatt tgtcgaggct gtaaatgagc ttggtggcat
     7621 atactatgat gtgccatacg acttaaatga acctaacaca gatgatactg gtaagattaa
     7681 aattaaaaaa gggtaccaaa aattaaatgg tgatgaggct ttagcagttg ctagaactag
     7741 acatcatgat tcagacttaa aacgtggaca acgtcaaatg gaattaatta agattttatt
     7801 ccaaaaagca caggaagttg attctattga taaacttgat aacgtgattc aaattgtagg
     7861 caaaaatgca aagcataatt taactaactc tgaaattaaa gctttagcaa aaatgtactt
     7921 aacaaatgat gttgaaatta aaactgcgca attaaaaggt aaagatgata tgttaaatgg
     7981 tatttactat tatcatccaa gtgttgaaag cattcaaaaa tatgcaaact tacttcgtaa
     8041 agacttagaa ttatcaccta ttaatgataa aaatgatttc ttagatcaac gtgtcattaa
     8101 tcattatggt tcattaatac cgttaacgcc tttagatagt agtttattga gaaaagaaca
     8161 aaatgatacg acagataaag ataagacatc taacgagaac aatgattcaa ctaataacag
     8221 tgattccagc aatcaacaac aacctgctac agatcaaaac ttaaatcaaa atcaaggtgg
     8281 cacacaacaa gcgccacaag cttcaaataa ccaaaatggt gttgtaaatt aatattatat
     8341 gacgattaac atttactatt tatgaaagga gcatcataca tgagtagaaa aacatacgaa
     8401 aagattgcaa atataaatgg catgtttaat atgttagaac aacaaatcat tcatagccaa
     8461 gatatggctc attttagaag tgaatttttt tacgtcaatc atgagcatcg agaaaactat
     8521 gaagcactcc taatttatta caaaaatagt atcgacaatc ctattgtaga tggtgcatgt
     8581 tatattttag ccctacctga aattttcaat agtgttgatg ttttcgaatc agagttacca
     8641 ttttcatggg tatatgatga aaatggcatt accgaaacaa tgaaatcact aagcattcca
     8701 ttacaatatt tagttgcagc agcattagaa gtaactgatg tgaatatatt taagccttca
     8761 ggatttacaa tgggaatgaa taattggaat attgctcaaa tgcgaatctt ttggcaatat
     8821 acagcaatta ttagaaaaga agcactataa cattaataat taattagcta taaagatgat
     8881 tcttgtgaat catctttata gcttttttat gtctaattat ttttgaggaa aataacaatc
     8941 gttattctat gttattatta gtaaattaaa tgtaaatgat tttgttagga tgtggaggaa
     9001 ttttatgttt tcaaaagtaa acaatcaaaa gatgttagaa gattgcttct atataagaaa
     9061 gaaagtgttt gtagaagaac aaggcgtccc tgaggaaagt gaaattgatg aatatgaatc
     9121 tgaatctatt cacctcattg gatatgataa tggacagcca gttgccactg ctcgaatacg
     9181 ccctattaat gaaacaactg tcaaaataga acgagtagct gtgatgaaat cacatcgtgg
     9241 acaaggaatg ggtagaatgc ttatgcaagc tgtagaatca ttagctaaag atgaaggttt
     9301 ttacgtagct actatgaatg cccaatgtca tgctatccca ttttatgaaa gtttaaactt
     9361 taaaatgaga ggtaatatat ttcttgagga aggcatcgag catattgaaa tgacaaaaaa
     9421 gttaacctcg cttaattaaa aaaagttgta tctattttag aaacatttgt aataaaccaa
     9481 ttcttaaatt gacatcaatt ctatttgatt tgtcacgtca ccattgagat tcaaaatttt
     9541 tttcattttt ttacagtgaa aatgtaaatt aagagtatat tacaaattgg ttaaatacgc
     9601 acaggtatat aaaacaggta ctataatgtt agtaataatt aataaatgtt aggagtaata
     9661 aatagaatgg cgaaaaaatt caattacaaa ctaccatcaa tggttgcatt aacgcttgta
     9721 ggttcagcag tcactgcaca tcaagttcaa gcagctgaga cgacacaaga tcaaactact
     9781 aataaaaatg ttttagatag taataaagtt aaagcaacta ctgaacaagc aaaagctgag
     9841 gtaaaaaatc caacgcaaaa catttctggc actcaagtat atcaagaccc tgctattgtc
     9901 caaccaaaaa cagcaaataa caaaacaggc aatgctcaag taagtcaaaa agttgatact
     9961 gcacaagtaa atggtgacac tcgtgctaat caatcagcga ctacaaataa tacgcagcct
    10021 gttgcaaagt caacaagcac tacagcacct aaaactaaca ctaatgttac aaatgctggt
    10081 tatagtttag ttgatgatga agatgataat tcagaacatc aaattaatcc agaattaatt
    10141 aaatcagctg ctaaacctgc agctcttgaa acgcaatata aagccgcagc acctaaagct
    10201 aaaactgaag cgacacctaa agtaactact tttagcgctt cagcacaacc aagatcagtt
    10261 gctgcaacac caaaaacgag tttgccaaaa tataaaccac aagtaaactc ttcaattaac
    10321 gattacattc gtaaaaataa cttaaaagca cctaaaattg aagaagatta tacatcttac
    10381 ttccctaaat acgcataccg taacggcgta ggtcgtcctg aaggtatcgt agttcatgat
    10441 acagctaatg atcgttcgac gataaatggt gaaattagtt atatgaaaaa taactatcaa
    10501 aacgcattcg tacatgcatt tgttgatggg gatcgtataa tcgaaacagc accaacggat
    10561 tacttatctt ggggtgtcgg tgcagtcggt aaccctagat tcatcaatgt tgaaatcgta
    10621 cacacacacg actatgcttc atttgcacgt tcaatgaata actatgctga ctatgcagct
    10681 acacaattac aatattatgg tttaaaacca gacagtgctg agtatgatgg aaatggtaca
    10741 gtatggactc actacgctgt aagtaaatat ttaggtggta cggaccatgc cgatccacat
    10801 ggatatttaa gaagtcataa ttatagttat gatcaattat atgacttaat taatgaaaaa
    10861 tatttaataa aaatgggtaa agtggcgcca tggggtacgc aatttacaac tacccctact
    10921 acaccatcaa aaccaacaac accgtcgaaa ccatcaactg gtaaattaac agttgcagca
    10981 aacaatggtg tcgcacaaat caaaccaaca aatagtggtt tatatactac tgtttacgac
    11041 aaaactggta aagcaactaa tgaagttcaa aaaacatttg ctgtatctaa aacagctaca
    11101 ttaggtaatc aaaaattcta tcttgttcaa gattacaatt ctggtaataa atttggttgg
    11161 gttaaagaag gcgatgtggt ttacaacaca gctaaatcac ctgtaaatgt aaatcaatca
    11221 tattcaatca aatctggtac gaaactttat acagtacctt ggggtacatc taaacaagtt
    11281 gctggtagcg tgtctggctc tggaaaccaa acatttaagg cttcaaagca acaacaaatt
    11341 gataaatcaa tttatttata tggctctgtg aatggtaaat ctggttgggt aagtaaagca
    11401 tatttagttg atactgctaa acctacgcct acaccaatac ctaagccatc aacacctaca
    11461 acaaataata aattaacagt ttcatcatta aacggtgttg ctcaaattaa tgctaaaaac
    11521 aatggcttat tcactacagt ttatgacaaa actggtaagc caacgaaaga agttcaaaaa
    11581 acatttgctg taacaaaaga agcaagttta ggtggaaaca aattctactt agttaaagat
    11641 tacaatagtc caactttaat tggttgggtt aaacaaggtg acgttattta taacaatgca
    11701 aaatcacctg taaatgtaat gcaaacatat acagtaaaac caggcactaa attatattca
    11761 gtaccttggg gcacttataa acaagaagct ggtgcagttt ctggtacagg taaccaaact
    11821 tttaaagcga ctaagcaaca acaaattgat aaatctatct atttatttgg aactgtaaat
    11881 ggtaaatctg gttgggtaag taaagcatat ttagctgtac ctgctgcacc taaaaaagca
    11941 gtagcacaac caaaaacagc tgtaaaagct tatactgtta ctaaaccaca aacgactcaa
    12001 acagttagca agattgctca agttaaacca aacaacactg gtattcgtgc ttctgtttat
    12061 gaaaaaacag cgaaaaacgg tgcgaaatat gcagaccgta cgttctatgt aacaaaagag
    12121 cgtgctcatg gtaatgaaac gtatgtatta ttaaacaata caagccataa catcccatta
    12181 ggttggttca atgtaaaaga cttaaatgtt caaaacctag gcaaagaagt taaaacgact
    12241 caaaaatata ctgttaataa atcaaataac ggcttatcaa tggttccttg gggtactaaa
    12301 aaccaagtca ttttaacagg caataacatt gctcaaggta catttaatgc aacgaaacaa
    12361 gtatctgtag gcaaagatgt ttatttatac ggtactatta ataaccgcac tggttgggta
    12421 aatgcaaaag atttaactgc accaactgct gtgaaaccaa ctacatcagc tgccaaagat
    12481 tataactaca cttatgtaat taaaaatggt aatggttatt actatgtaac accaaattct
    12541 gatacagcta aatactcatt aaaagcattt aatgaacaac cattcgcagt tgttaaagaa
    12601 caagtcatta atggacaaac ttggtactat ggtaaattat ctaacggtaa attagcatgg
    12661 attaaatcaa ctgatttagc taaagaatta attaagtata atcaaacagg tatgacatta
    12721 aaccaagttg ctcaaataca agctggttta caatataaac cacaagtaca acgtgtacca
    12781 ggtaagtgga cagatgctaa ctttaatgat gttaagcatg caatggatac gaagcgttta
    12841 gctcaagatc cagcattaaa atatcaattc ttacgcttag accaaccaca aaatatttct
    12901 attgataaaa ttaatcaatt cttaaaaggt aaaggtgtat tagaaaacca aggtgctgca
    12961 tttaacaaag ctgctcaaat gtatggcatt aatgaagttt atcttatctc acatgcccta
    13021 ttagaaacag gtaacggtac ttctcaatta gcgaaaggtg cagatgtagt gaacaacaaa
    13081 gttgtaacta actcaaacac gaaataccat aacgtatttg gtattgctgc atatgataac
    13141 gatcctttac gtgaaggtat taaatatgct aaacaagctg gttgggacac agtatcaaaa
    13201 gcaatcgttg gtggtgctaa attcatcggc aactcatatg taaaagctgg tcaaaataca
    13261 ctttacaaaa tgagatggaa tcctgcacat ccaggaacac accaatatgc tacagatgta
    13321 gattgggcta acatcaatgc taaaatcatc aaaggctact atgataaaat tggcgaagtc
    13381 ggcaaatact tcgacatccc acaatataaa taagcaacat gaacatagga tcaaaagtca
    13441 tcccccacta tcaatcatgg gggatgacct ttgatccctt ttttatacat acacaagcaa
    13501 aaatagcggt gattgtttac catcaatttt aacaatcacc gctacttttg cttgtaattc
    13561 atgattcaat ttttgttgtg tgcacaatga cactaaatta tgtgtttgct attgtcgtgt
    13621 tacaacgata tgcgtcgttg atttaactta tcaagtaatt gatttaaatt gtctaattcg
    13681 acttccgata aacattgaca tcttgcttca atcaattcgc aacgtgcatt atttatttgt
    13741 gaaattaatg tacgtgcttg atcagtcaaa attaattctt tacatcttaa atcttcgcta
    13801 gattgttgac ttgtgatgta acctttcaaa actaatttct taatccacct tgaaactata
    13861 gattgttccc tgctaatctt catcgtcaaa tcatactgtg ataagcgatc gtaattaaat
    13921 aaaatacgga gaagttctag ctgttcagat gtgatatccg tgcgttgtcc aaatcttcta
    13981 ttcactaagt ttaagtcatt gttagtcagt gtaataagtt tttcaagttg tttatacatg
    14041 ttgatctact ccactacata ttatttataa tattatatgc tttttttata atttttacaa
    14101 tactattcga cacaatagac aaatttgttg cataactaat acaaaatata ataaattagt
    14161 aagagtctta tggacataaa ggagataaaa tatgacttca ttaaaagaga gagattattt
    14221 ttttgacaac gcaagagcaa ttttaatatt attagtcgta tttggacata tgttacaacc
    14281 ctacactagt ggcgataaat atttatcagc attataccta gttatttata gtttccatat
    14341 gccaacattt ttgtttatat ctggttattt cgcgaaaaat attgataaac catactattt
    14401 agaaaaaatt tcaaaacgtt tgatagtacc ttatatgata ttttttgcat tcttttcaat
    14461 atattatttc ttaacaggta aaagtgacga attacaactt gatcctttta acccagtatt
    14521 tgcgttatgg tttttgatca cgctattttt ctttcatgtc attttagtaa tagttagaag
    14581 atttaatcca tataaagtgc tatcagtttc aattattata tctattggag caggtttttc
    14641 agataacatc gatagctact tgagcatttc aaggacaatc gtatttttcc caatatttta
    14701 cctaggttac attttcacca aaaaacatac ggctattttt aaaaataaaa aactaatacc
    14761 agtatctatc attaccttta ttttgttttt tatcatttac gtgattcatc ctatcaatgc
    14821 agattggtta ttgggaagtt caccatatac ttcacttgaa aatgaaggac agagtatatt
    14881 cagtcctttt aaacgactta tattatatgg aattatatta atcgcaatga ctgcgtttct
    14941 aaatttaatg tcaacaaaga aaaaattata tacttatatt ggtagtcgta cgctatacgt
    15001 atatttatta catggtttaa ttattggcat tgttagagga tttgaatggt acccattcga
    15061 taatcctata tcattaatga cttatcttta tttaataagt atatctgtaa tcatcgtata
    15121 tgtattatct acaaactttg tttgtaaatg gacaaatcca ataattaatt tacaaagacc
    15181 atcacagttt aaagattcat aattttatag tgtctaagta cattaactgt aac
//
LOCUS       DAPDIM010000061        15021 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000061 DAPDIM010000000
VERSION     DAPDIM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 15021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15021
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.061"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(353..1066)
                     /locus_tag="RFE25_002167"
     CDS             complement(353..1066)
                     /locus_tag="RFE25_002167"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDU2817204.1"
                     /translation="MAKLNVEVFADGADIEEMKAAYKNKQVDGFTTNPSLMAKAGVTD
                     YKAFAEEAVKEIPDASISFEVFADDLETMEKEAAILKQYGENVFVKIPIVNTKGESTI
                     PLIKKLSADNVRLNVTAVYTIEQVKEITEAVTEGVPTYVSVFAGRIADTGVDPLPLMK
                     EAVKVTHSKDGVKLLWASCRELFNVIQADEIGADIITCPADVVKKVNTNLGRDINELS
                     VDTVKGFAKDIQSSGLSIL"
     gene            1326..1628
                     /locus_tag="RFE25_002168"
     CDS             1326..1628
                     /locus_tag="RFE25_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817205.1"
                     /translation="MSRSKKYFYLSSLMIILSFFFNTNNVFLSGFFNSFIKLILFCSV
                     INSIVLILSIIFADRSIKSLKPDADWIRIASKSLPWIILIVILVHIFSIVRTFGFI"
     gene            1884..2249
                     /gene="crcB"
                     /locus_tag="RFE25_002169"
     CDS             1884..2249
                     /gene="crcB"
                     /locus_tag="RFE25_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDU2817206.1"
                     /translation="MQYVYIFIGGALGALLRYLISFLNTDGGFPIGTLIANLTGAFVM
                     GLLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQLELIHMFDHQQFITLLLYAVTS
                     YVFGILLCYVGIKLGGGLS"
     gene            2246..2599
                     /locus_tag="RFE25_002170"
     CDS             2246..2599
                     /locus_tag="RFE25_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CrcB family protein"
                     /protein_id="HDU2817207.1"
                     /translation="MISIILVMIGGGFGAIARSAITDYFNHKFTSKLPIATLIVNLVG
                     SFLIGLTIGLSISISWFPAFFVTGFLVGLTTFSTLAKELTLMMTPKFDINLFLNYSLL
                     QFIIGFIACYIGYHI"
     gene            2998..4533
                     /locus_tag="RFE25_002171"
                     /pseudo
     CDS             2998..4533
                     /locus_tag="RFE25_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(4596..5429)
                     /locus_tag="RFE25_002172"
     CDS             complement(4596..5429)
                     /locus_tag="RFE25_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDU2817208.1"
                     /translation="MEVKTFYNGNTMPQIGLGTFRVENDENCMESVKYAIEQGYRSID
                     TAKVYGNEEQVGAGIRAGLESTGIAREDLFITSKLYFEDFGRENVAAAYEASLSRLGL
                     KYLDLYLVHWPGTNEAVMVDTWKGMEDLYKNNKAKNIGVSNFEPEHLEALLAQVSIKP
                     VINQVEYHPYLTQHKLKLYLAAQHIVMESWSPLMNAQILNDETIKDIAQELGKSPAQV
                     VLRWNVQHGVVIIPKSVTPNRISENFQIFDFELSDEQMTRIDGLNQDKRIGPDPKTFE
                     G"
     gene            complement(5641..6549)
                     /locus_tag="RFE25_002173"
     CDS             complement(5641..6549)
                     /locus_tag="RFE25_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HDU2817209.1"
                     /translation="MDLSSPVVIGLIIAVVIALIFFVLFLVALGSKKKVKRQTEEKYE
                     QQEQNIKKSHEEALEKERIQNKKTITKQQEDYNHMVSTKDREIDALKLFSKNHSEYVT
                     DMRLIGIRERLVKEKRIRPEDMHIMANIFLPKDGFNNIERISHLVLTRTGLYIIDSQL
                     LKGHVYNGISGGQFKDLPPMEQVFDTLDLDKSRPQTIVMDQNDDKRSLSFVNYSDQIE
                     AIKQLAEDLQKELGAKYTPTSILYFNPKNEGDVTISNYNQNSAVKVLVGAEQLDEFFN
                     KFVFHGRIQYNVEDLQQMMDKIESFN"
     gene            complement(6671..7867)
                     /locus_tag="RFE25_002174"
     CDS             complement(6671..7867)
                     /locus_tag="RFE25_002174"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDU2817210.1"
                     /translation="MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVAC
                     ETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQS
                     PDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKR
                     LSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHADDVTLEQIQEDIKA
                     HVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCF
                     SGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKV
                     SEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEEL
                     KDAVKY"
     regulatory      complement(7973..8084)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            8239..9831
                     /gene="pckA"
                     /locus_tag="RFE25_002175"
     CDS             8239..9831
                     /gene="pckA"
                     /locus_tag="RFE25_002175"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDU2817211.1"
                     /translation="MSVDTYTETTKIDKLLKKPTSHFQLSTTQLYNKILDNNEGVLTE
                     LGAVNASTGKYTGRSPKDKFFVSEPSYRDNIDWGEINQPIDEETFLKLYHKVLDYLDK
                     KDELYVFKGYAGSDKDTMLKLTVINELAWHNLFAKNMFIRPESKEEATKIKPNFTIVS
                     APHFKADPEVDGTKSETFVIISFKHKVILIGGTEYAGEMKKGIFSVMNYLLPMQDIMS
                     MHCSANVGEKGDVALFFGLSGTGKTTLSADPHRKLIGDDEHGWNKNGVFNIEGGCYAK
                     AINLSKEKEPQIFDAIKYGAILENTVVAEDGSVDFEDNRYTENTRAAYPINHIDNIVV
                     PSKAAHPNTIIFLTADAFGVIPPISKLNKDQAMYHFLSGFTSKLAGTERGVTEPEPSF
                     STCFGAPFFPLHPTVYADLLGELIDLHDVDVYLVNTGWTGGKYGVGRRISLHYTRQMV
                     NQAISGKLKNAEYTKDSTFGLSIPVEIEDVPKTILNPINAWSDKEKYKAQAEDLIQRF
                     EKNFEKFGEKVEHIAEKGSFNK"
     gene            complement(10209..10955)
                     /locus_tag="RFE25_002176"
     CDS             complement(10209..10955)
                     /locus_tag="RFE25_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDU2817212.1"
                     /translation="MPIESFTHQFEEITYLSDDLQVKALMMTPHHEVNRIVVYLRGGK
                     GQVGRVRAGRLMQFSDSQTLVIGPYYRGNNGSEGKDEFYRGDLNDVTQLLRLLHDKYP
                     HAFIHMVGFSRGGLQGLLTFQDLPVTSYTIWGGVSDIDLMYEERVDLRGMLRRMIGHP
                     KKDRAAYEARQAIPNINENSPPILIVHGGKDQQVGIHHAYYLADQLELKGATHETFYQ
                     MAEGHVPRPPAMVETLTYIKEFMKQVELHS"
     gene            complement(10960..11433)
                     /gene="ytkD"
                     /locus_tag="RFE25_002177"
     CDS             complement(10960..11433)
                     /gene="ytkD"
                     /locus_tag="RFE25_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase YtkD"
                     /protein_id="HDU2817213.1"
                     /translation="MKFRDKDNRQVNLTFKKDNEIADGNHVLAIPTFKNQLLFTKHNL
                     RGIEFPGGKRERGESSAEAVTRELYEETGAKVKNIHYIAQYTIETHDQTDFVKDVYFI
                     EVESLVSKNDYLETAGPVLFNCINDIELAQRSFLLQDSTILKCVERVQSLGFYQT"
     gene            11499..11756
                     /gene="yidD"
                     /locus_tag="RFE25_002178"
     CDS             11499..11756
                     /gene="yidD"
                     /locus_tag="RFE25_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDU2817214.1"
                     /translation="MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAF
                     KGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH"
     gene            complement(11753..12754)
                     /gene="menC"
                     /locus_tag="RFE25_002179"
     CDS             complement(11753..12754)
                     /gene="menC"
                     /locus_tag="RFE25_002179"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HDU2817215.1"
                     /translation="MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAY
                     FGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSFETYEAALKLVDSLENTPAARAT
                     IVMALYQMFHVLLSFSVAYGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLR
                     ELDFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIAL
                     DEKATSLLDIINLIELYNVKVVVLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYG
                     LSRYFTAMLARKGDYPGDVTPAGYYFDQDVVTKSGILKEGRLEFRPPLVDITQLQPY"
     gene            complement(12759..14237)
                     /gene="menE"
                     /locus_tag="RFE25_002180"
     CDS             complement(12759..14237)
                     /gene="menE"
                     /locus_tag="RFE25_002180"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HDU2817216.1"
                     /translation="MDFWLYKQAQQNGHHIAITDGQESYTYQNLYCEASLLAKRLKAY
                     QQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLIFCTLP
                     LELRGFQIVSLDDIEFAGRDITTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNL
                     DDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGLS
                     VLLRAVIEGFTVRIVDKFNAEQILTMIKNERITHISLVPQTLNWLMQQGLHEPYNLQK
                     ILLGGAKLSATMIETALQYNLPIYNSFGMTETCSQFLTATPEMLHARPDTVGMPSANV
                     DVKIKNPNKEGHGELMIKGANVMNGYLYPTDLTGTFENGYFNTGDIAEIDHEGYVMIY
                     DRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESDISK
                     AQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKLQRNKLYRG"
     gene            complement(14396..14851)
                     /locus_tag="RFE25_002181"
     CDS             complement(14396..14851)
                     /locus_tag="RFE25_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4909 domain-containing protein"
                     /protein_id="HDU2817217.1"
                     /translation="MKICLMLYLLIFLSSCGTNNKIVGQRFEIQQHNETIGSIYFSAD
                     YAHIRGIEKGTAKYFIDKVGSKRYLFIEYIPDNVLNCKPDFWKTLKYKKDKVTYYVYL
                     IENLDDEVFHLSALQDMNRIPIDIADDVATMGKSPHQNDRMTLKLNKNN"
BASE COUNT         4809 a         2764 c         2233 g         5215 t
ORIGIN      
        1 cgtgtcatca agtgcaaaat aatttagaac taatacaaac ataaaaactt ttgctttacg
       61 cttaaaatca aaagtcacat acctagatat aagtacaact tgtatatttt gtactctaat
      121 aagtatgtgg cttaaataat atttaattct tgagttgcat atagtaattg tttttattca
      181 ttttctaaaa tatgcgagac taatttcctt ttctactcct gttgaatcaa tttagacttt
      241 tttataactc gggcttttac ttagctgaat tttgacttct tcttcattaa taactatgat
      301 ggaaaaaccc ccataagcac aatgcctatg agggtttaaa tatgtttata aattatagaa
      361 tagaaagacc tgaagattga atatctttcg caaagccttt aactgtatct actgataatt
      421 cgttaatatc gcgacctaag tttgtattca cttttttcac aacatctgca gggcatgtaa
      481 taatatctgc accaatttca tcagcttgaa tcacattgaa taattcgcgg caacttgccc
      541 ataataattt aacgccgtct ttactatgcg taacttttac agcctctttc attaatggta
      601 atggatctac gcctgtatct gcaatacgtc ctgcaaatac tgaaacatat gttggcacac
      661 cttcagttac tgcttcagtt atttctttaa cttgttcaat tgtgtaaaca gccgtaacgt
      721 ttaatctcac attgtcagct gaaagttttt taattaaagg aatcgttgat tcaccttttg
      781 tatttacaat aggaatttta acaaatacat tttcgccata ttgttttaaa attgctgctt
      841 ctttttccat agtttctaaa tcgtctgcaa atacttcaaa tgaaattgaa gcatctggaa
      901 tttctttcac agcttcttca gcaaaagctt tgtaatctgt tacgcccgct ttcgccatta
      961 aactaggatt tgttgtaaaa ccatccactt gtttgttttt ataagctgct ttcatttctt
     1021 caatatctgc accgtccgca aatacttcta catttagttt agccatataa tatagcctcc
     1081 ttgattctta ttaaaatttt aacaacatct gcatgtcttt ttcttacaac catttgtaaa
     1141 aaatgatttt tatttctttg ttatataaaa catttatatc acgcttttat aatatatagc
     1201 taattttttg cctatatttt ttaaaaatga ctttagcaaa cattgtgtct acaagttaat
     1261 aaaactattg ttttatgatt gtttatgata cgatatgtaa atgataatca tccaggaggt
     1321 ctagcatgtc tcgttcaaaa aaatactttt acttatctag cttaatgatt attttaagct
     1381 ttttctttaa tacaaataac gttttcctaa gtggattttt taattctttt attaaattaa
     1441 tacttttctg cagtgttatt aactcaattg tactaatttt gtctataatt tttgcagatc
     1501 gttcaattaa atcactaaag cctgatgcag attggattag aattgcgagt aaaagtttgc
     1561 cttggattat tctaattgtt attttagtac atatcttttc aattgttcgt acattcggtt
     1621 ttatttaaaa aagataaaat gtcaatgtag cgttaataca aaacaataca atgtatcatg
     1681 ctataatgag taaaacaatt tgatgacgtt gttgcgtata aaaaatatta gattttcgaa
     1741 atcataacta tgcatctaat cgctatagtt atacaacaag atataacata taatgaggtt
     1801 tgataatgca tcgacaattt ttgtcgtcgt gttgccaaaa cctctttttt aaattcaaac
     1861 tacttctttt cgaggtgaac caaatgcaat atgtatatat ttttatcggt ggtgctttag
     1921 gcgctttatt acgttacctc atttcttttc tgaatactga cggaggtttt ccaatcggaa
     1981 cactgatagc caatttgact ggtgcctttg taatgggatt gctaacagcc ttaacaattg
     2041 catttttttc aaaccatccg accctaaaaa aagctattac gactggtttt cttggtgctt
     2101 taacgacttt ttcaacattt caattagaat taatacatat gtttgatcat caacaattta
     2161 taactttact actatatgct gtaacaagtt atgtctttgg tattttgtta tgttacgtcg
     2221 gtataaaact aggtggtggt ttatcatgat atcaatcatt ttagtcatga ttggcggcgg
     2281 ttttggcgca attgctagaa gtgccattac tgattatttt aatcataaat ttacttcaaa
     2341 gttacctatc gcaacattga tagtaaatct agttggtagt tttttaattg gattaactat
     2401 aggcctatca atttcaatct catggttccc tgcgttcttt gtcaccggtt ttttagttgg
     2461 cttaacaact ttctcaacgt tagccaagga acttacatta atgatgacac caaaatttga
     2521 tattaacctt tttctcaatt attcactttt acaattcatc attggattta tagcttgtta
     2581 tattggctat catatttaaa aataaaatgc ttcattcagc aaataggtaa attacgacac
     2641 cttcctgaac gaagcatttt ttaattttca tgcaaatttt ttaacaccat ataatgccta
     2701 tcaaaataaa acaatctttg ttgccgttta aataatgtga atgtcaataa attctccaaa
     2761 ctagtcgaaa ataaaacagg ctgggacata aatccctaaa aaaacagcag taagataatt
     2821 ttcaattaga aaatatctta ctgctgttct ctatttatac aatacttcgt attgaatggc
     2881 ttcgctttcc tagggtgccg tctcagcctc ggtcttcgac tggcactgct ccctcaggag
     2941 tctcgccatt aatactacgt attaacatgt aattttactt ttacatactt taaaaaaata
     3001 agacactttg cccaacttac actaccaata gaaacttctg ttagaattcc ttaaaatgat
     3061 atttcgcgat atgtaaatga aattgttgaa acgatacctg atagcgaatt cgatgaattc
     3121 agacatcatc gtggcgcaac atcctatcat ccaaaaatga tgttaaaaat catcttatat
     3181 gcatatactc aatctgtatt ttctggtcgt agaatagaga aattacttca tgacagtatt
     3241 cgaatgatgt ggttagctca agatcaaaca ccttcttata aaactattaa tcgttttaga
     3301 gtgaatccta atactgatgc gttaattgaa tctttattta ttcagttcca tagtcaatgt
     3361 ttaaagcaaa atcttattga taataattca atttttattg atggtacata agtagaagct
     3421 aatgccaata gatatacatt tgtgtggaag aaaagtattc aaaatcacga gaagaaatag
     3481 atttaattgg tagtcattta gataaagaaa tcgaagattt aaatcattct atttagaacg
     3541 aagattgtgc tcaaattaga aaacagaccc gtaaaaaaga actgagatta agaagttcaa
     3601 aaagaaattt gatgattatt ccgaaagaaa aaataaatat gaagaacaaa aatcgattct
     3661 taaagataga aatagctttt ctaaaactga tcatgatgca acttttatga gaatgaagga
     3721 agaccatatg aaaaatggcc aacttaagcc aggatacaat ttacaaatag cgacaaattc
     3781 tcaatttttt tatcctatga cctatttcaa accccaacag atactagaac tttaattcca
     3841 tttttaacaa tgattcaaaa taccttcggt tatttaccag agtatattgt agctgatgca
     3901 ggttatgata gtgagcaaaa ctatatggct attatagatg attttaataa aacgccactt
     3961 attacgtatg gcatgtttat taaagataaa actagaaagt ttaaaagtga catttttaac
     4021 actcaaaatt ggaaatatga cgaacttaat gatgaattta tatgtcctaa taacaaaaga
     4081 ataggtttta aaagatatgc ataccgtaat gatagatatg gttttaaacg tgacttcaag
     4141 ctatatgaat gcgatgactg ttcagcatgt tctttgaggc aacaatgcat gaaaccaaat
     4201 tcgaaatcca ataagaaaat catgaagaat tataattggg aatactttaa agcccaaatt
     4261 aatcaaaagc tttctgaacc agaaacgaaa aaaatctata gtcaaagaaa aattgatgta
     4321 gagcttgttt ttggatttat gaaggctatt ttgggtttca ctcgaatgtc agttcgagga
     4381 ataaataatg ttaaacgaga gctaggtttt gtattaatgg cacttaatat aaggaaaata
     4441 gcagctcaac gagctgtaca ttataaaata catatcaaaa aagctgattt ctatcaaata
     4501 attaatagaa atcaactttt ttacattgcc taagaactta atgtcccaag ccctgacaat
     4561 tcatctaacc ttttcatcag ttgagtgatt ttaatctatc cttcaaaagt ttttggatca
     4621 ggtccaattc tcttatcttg atttaaacca tcaattcgcg tcatttgttc atctgataat
     4681 tcgaaatcaa atatttggaa gttttcagag attctgtttg gtgttaccga tttagggatt
     4741 ataaccacac catgctgcac attccatctt aaaacaactt gggcaggtga ctttcctaat
     4801 tcttgagcaa tgtctttaat tgtctcatca tttaaaattt gtgcattcat caatggtgac
     4861 caagattcca tcacgatatg ttgtgctgcc aaatataatt tcaatttatg ttgcgttaaa
     4921 tatggatgat attcaacttg attaattaca ggtttaattg acacttgtgc caacaaagct
     4981 tccaaatgtt caggttcaaa attgctgaca cctatatttt tagctttatt atttttatat
     5041 aaatcttcca tacctttcca tgtatcaacc attacggctt cgttcgtgcc tggccaatgt
     5101 actagataca aatctaagta ttttaaacct aatctagata aactagcttc gtaagcagct
     5161 gctacatttt cacgaccgaa atcctcaaaa tataattttg aagtaataaa taagtcttct
     5221 ctagcaatac cagttgactc caatccggca cgaatgccag cacctacttg ttcttcattc
     5281 ccataaactt ttgcggtatc aatactacga tatccttgtt caatggcata cttaacactt
     5341 tccatgcaat tttcatcatt ttccacacga aatgtcccta aaccaatttg tggcatcgtg
     5401 tttccattat aaaatgtttt aacctccata aatatcgcct cacctttttg atgtattata
     5461 ccctgttatc ataacaaatc tgagttgaat acatgagaaa aaacacttag agcaatcaac
     5521 cactaaaatt ctagtaatat ctctcaaaca ttaatcaaat tgtaaaagca attatgttta
     5581 atttatgaca aactaaaaaa gccgaagtca caacatatag tcatcacttc agcctaacat
     5641 ttaattgaat gattcaattt tatccatcat ttgttgtaag tcttccacgt tgtattgaat
     5701 acgaccatgg aatacaaatt tgttaaagaa ctcgtctaat tgttcagcac cgacaagcac
     5761 tttgacagca ctattttgat tataatttga aatcgttaca tcgccttcat ttttaggatt
     5821 aaagtataaa attgaagttg gcgtatattt ggcacctaat tctttttgta agtcttcagc
     5881 caattgttta atcgcctcaa tttgatctga ataatttaca aaagataatg aacgtttgtc
     5941 atcattttga tccatcacaa tagtttgtgg tctagattta tctaaatcca atgtatcaaa
     6001 tacttgttcc attggtggta aatctttaaa ttgaccgcca ctaataccat tataaacatg
     6061 accttttaac aattgagaat caataatata aagaccagtt cttgttaata ctaaatgact
     6121 aattcgttca atattattaa agccatcctt tggtaaaaag atatttgcca taatgtgcat
     6181 atcttctggt cgaattcgtt tttctttaac taatctttca cgaataccaa ttaatctcat
     6241 gtccgttaca tattcactat gatttttcga gaacaatttt aatgcgtcaa tctcacgatc
     6301 ttttgtacta accatgtgat tataatcttc ttgttgtttt gtaattgtct ttttattttg
     6361 aatacgctct ttctctaaag cttcttcatg agacttttta atgttttgtt cttgttgttc
     6421 atacttttct tctgtttgtc gcttaacttt tttcttacta cctaaggcaa ctaagaaaag
     6481 gacaaaaaag attaatgcaa tgactactgc aataatgagt ccaatgacta ccggtgaaga
     6541 taaatccatc acaacaacgc tcctttttaa tatatgaata actttaatta taatagaaaa
     6601 gctaaagatt ttcgatacat attatcattt atataccgaa aatcttttat ttagctatat
     6661 taaattcatc ttaatatttt actgcgtctt ttaattcttc cactttgtct aatttttccc
     6721 atgggaataa tacatctgta cgtccaaaat gaccataagc agcagtttgt ttgtaaatcg
     6781 gttgtttcaa atcaagcatt ttaataatgc ctgcaggtct taggtcaaag tgttttctaa
     6841 ctgcttcgac aagttgtcct tcagaaactt tacctgttcc aaatgtatca attgcaattg
     6901 acactggttc tgcaacacca atcgcatatg ccaattgtac ttcacattga tctgctaaac
     6961 ctgctgcaac aatattttta gccacataac gtgcagcata tgcagctgag cggtctactt
     7021 ttgtaggatc cttaccactg aagcatccgc caccatgacg tgcatagcca ccatacgtat
     7081 caacaatgat tttacgtcct gttaatcctg catcaccttg aggtccaccg attacaaagc
     7141 gtcctgtagg attgatgtag aatttagttt gttcattaat caagttttct ggaacagttg
     7201 gataaatgac atgcgctttg atgtcttctt gaatttgttc aagtgtcaca tcatcagcat
     7261 gttgtgttga tacgacaatc gtatcaatac gtactgggtt atcattttca tcatattcaa
     7321 cagtgacctg aactttaccg tctggtcgta aataatttaa cgtaccatct ttacgcacat
     7381 cagataaacg ttttgccaat tgatgtgata aataaattgc tagaggcatg tacgtttctg
     7441 tttcattcgt tgcgtaacca aacattaaac cttggtcacc tgcacctgtt gcttcaattt
     7501 cttcttcgct atctttatca cgatactcta atgctttatc cacgccttgt gcaatgtcag
     7561 gtgattgttc atcaatcgca gttaaaattg ccattgtttc ataatcataa ccatattttg
     7621 ctcttgtgta tccaatttct ttaattgttt ctctaacaac tttcggaata tcaacatatg
     7681 ttgttgtaga aatttcgccg gcgatcaatg ccatacctgt tgtaacagtt gtttcacaag
     7741 ctacacgtgc atttgggtcg tcttttaaaa tagcatctaa tattgcatct gacacttggt
     7801 cagcgatttt atctgggtgt ccttctgtaa cagactctga agtaaataat cgtttgttat
     7861 ttaacatagt ttgctccttt aaatttatat tacgaaaatt ctctctctgt gagctaaata
     7921 aaaaagacct tctaactatt aatatagaga gaaggcctaa tacgtccatt cgctcttatc
     7981 gttcagacct atttgtctgc aaacggtttg gcacctttct tttataaaaa aagaggttgc
     8041 tgggtttcat tgggtccatg tccctccacc actcaggata agagaatccg ttaaaaataa
     8101 tagtacctaa ttaatgaatt aatgtcaatt tttcacaaat aaatttacag taaaatattg
     8161 tagattaatt atgttaatgt gttatactaa ttaaatgtaa aggcttacat ttaaattatc
     8221 gctttggagg gatttaggat gtcagtagac acatacactg aaacaactaa aattgacaaa
     8281 ttactgaaaa aaccaacgtc acattttcaa ctttcgacga cacaacttta taataaaatc
     8341 ttagacaata acgaaggggt attaacagaa cttggtgctg ttaatgcaag tactggaaaa
     8401 tatactggtc gttcgcctaa agacaaattt tttgtctctg aaccttcata tagagataac
     8461 attgattggg gagaaattaa tcaacctatc gatgaagaaa ctttcttgaa gttataccat
     8521 aaagtactag actatttaga taaaaaagat gaactatacg tatttaaagg ctacgctggt
     8581 agcgataaag atacaatgtt aaaacttaca gtcatcaatg aattagcatg gcataattta
     8641 tttgctaaaa atatgtttat tagacctgaa tcaaaagaag aagctacaaa gattaaacct
     8701 aacttcacta tcgtttctgc accacatttt aaagcagatc cagaagttga tggtactaaa
     8761 tctgaaacct ttgtcattat ttcatttaaa cacaaagtca ttttaatcgg cggtactgaa
     8821 tacgctggtg aaatgaaaaa aggtatcttc tctgtaatga attatctctt accgatgcaa
     8881 gatattatga gcatgcattg ctcagcaaac gttggtgaaa aaggcgatgt tgcattattc
     8941 tttggtctat ctggcactgg taaaacaacc ttatcggctg acccacaccg taaactaatc
     9001 ggtgatgatg aacacggatg gaataaaaac ggggtcttta atatcgaagg tggctgctat
     9061 gcaaaagcaa ttaatctttc caaagaaaaa gaaccacaga tttttgacgc aatcaaatat
     9121 ggtgcaattt tagagaacac tgtagttgca gaagatggtt cagtggactt tgaagacaat
     9181 cgttatacag aaaacacgcg tgccgcttat ccaattaatc acattgacaa tattgtagta
     9241 ccatcaaaag cagcacatcc aaatacaatt attttcttaa ctgcggatgc atttggtgtt
     9301 attccaccga tttcaaagtt aaataaagac caagcaatgt atcatttctt gagtggtttc
     9361 acttctaaat tagctggtac agagcgtggt gtgacagaac ctgaaccatc attctcaaca
     9421 tgtttcggag caccgttctt cccgttacac cctactgttt acgctgattt attaggtgaa
     9481 cttatcgatt tacatgatgt tgatgtttat cttgttaata ctggatggac tggcggaaaa
     9541 tatggtgtag gacgtagaat cagcttacat tacacacgtc aaatggtaaa ccaagcgatt
     9601 tctggcaaat tgaaaaatgc agaatataca aaagatagta cgtttggttt aagcattcct
     9661 gtagaaattg aagatgtacc gaaaacaatt ttaaatccaa ttaatgcttg gagcgacaaa
     9721 gagaaatata aagcacaagc agaagattta attcaacgtt ttgaaaagaa cttcgaaaaa
     9781 tttggtgaaa aagttgaaca tattgctgaa aaaggtagct tcaacaaata aatttgaata
     9841 ctaattaaag agccaaccgt tgttatagtc taacaatggt tggctcctct tattttatgt
     9901 gctaaaaatt tataggcaat tttattacaa caatgcacat ttaaggtgac cttcatgcca
     9961 aactcgcatc actcatttaa tggaagcagc acgtcttcac ataaagtacc ggttccttac
    10021 gctatgcatg ttgccccact ttgcataaag tacttatcgt taactcaacg caagttgttc
    10081 ctattcacaa aaagcacata cagttatctg catggagcac attttcattg aaagcgcata
    10141 cccctcattc aacgtatatc acacatcttc aaagcttgat agttcccatg cgcacaccac
    10201 gtttcatact agctatgcaa ctcaacttgt ttcataaact ctttaatata agtcaatgtt
    10261 tcaaccatcg ctggtggtct tggcacatgt ccttctgcca tttgataaaa tgtttcatgc
    10321 gtggcacctt ttaactctag ttggtccgct aaataatacg catgatgaat accaacttgc
    10381 tggtctttcc ctccatgtac aattaatatt ggcggactgt tttcattaat gtttggaatc
    10441 gcttggcgtg cctcatatgc cgctcgatct tttttcggat gaccaatcat tcttcgtagc
    10501 atgcctctta aatcgacacg ttcttcatac attaaatcaa tatctgagac accaccccag
    10561 attgtataac ttgttactgg taagtcttga aatgtcaaca atccttgtaa accacctcgc
    10621 gaaaaaccaa ccatgtggat aaatgcatgt ggatatttat catgtagcaa ccttaataat
    10681 tgcgtcacat catttaaatc gccacggtaa aattcgtctt taccttcact cccattgtta
    10741 cctcggtagt atggcccaat cactaaagtt tgactatctg aaaattgcat taatctacct
    10801 gcgcgcacac gtcctacttg acctttgcca cctcgcaaat aaactacaat gcgatttact
    10861 tcatgatgtg gtgtcatcat taaagctttt acttgtaagt catctgacaa atatgtaatt
    10921 tcttcgaatt gatgcgtaaa agattcaatt ggcattcgtt tacgtttgat aaaatccaag
    10981 tgattgcacc ctctctacgc attttaaaat ggtactatct tgcagtaaga aactccgttg
    11041 tgcgagttca atatcattga tacagttaaa caacactggc cctgctgttt ctaaataatc
    11101 gttcttgctt accaatgatt caacttcgat aaaatataca tcttttacaa aatcagtttg
    11161 atcatgtgtt tcaatggtat attgtgctat gtaatgaata tttttaactt tggcgcctgt
    11221 ttcttcatat aattcacggg taactgcttc agcactactt tccccgcgtt cccttttacc
    11281 accaggaaat tcaatccccc gtaaattatg tttggtaaaa agcaattgat ttttaaacgt
    11341 tggaatagct agcacatgat tgccatctgc tatctcatta tcctttttaa atgtcaaatt
    11401 aacttgacga ttatctttat ccctaaactt cacgcgcatc acatccctac attgtatgtt
    11461 aatataatag ttaattacta tcgttggagg cattaattat gaaaaagata ttcttggcga
    11521 tgattcattt ttatcaacgt ttcatttcgc cactcactcc accaacttgt cgtttttatc
    11581 caacatgttc agagtacact agagaagcga ttcaatacca cggtgctttc aaaggccttt
    11641 atttaggcat ccgtcgtatt ttaaaatgtc atccgcttca taaaggtggc tttgaccctg
    11701 ttccgttaaa aaaagacaag tcagcaagca agcattcaca taaacataac cattaatatg
    11761 gttgtaattg agttatatcc actaaagggg ggcgaaattc gagtcgcccc tcttttaata
    11821 tgcctgattt agtaaccaca tcttgatcaa aataataacc tgctggtgta acatctcctg
    11881 gataatcacc tttacgagca agcatcgctg taaaataacg gcttaaacca tattcgtaca
    11941 tgccgccaat aaccactttt acaccatgac ttttcaaagt atcaattgcc gtttgcactt
    12001 tatcaatgcc acctagacga aatggtttta atacaacaac tttcacattg tataattcta
    12061 tcaaattaat tatgtccaac aacgatgttg ccttttcatc aagggctatt ggaggtattg
    12121 ttccatccac tacttcatca agcatggaga tatctttaaa tggctcttcg atataaagaa
    12181 cctgttcacg cgctaatagc tgtaactgtg tgaaatcttg acgatccaat gactcatttg
    12241 catctataac caattgaaag tgaaagtcta attcccgtaa cactctaatt tgatgcatga
    12301 tttgaggcgt ccattttaat ttaattctgg tcggctttgt tgctttcaat gactctagtt
    12361 gtttatttga taagccgctc gctgtcgctc catatgctac tgaaaatgaa agcagtacat
    12421 gaaacatttg atacaatgcc atgacaatag ttgcccttgc agcaggcgta ttttccaatg
    12481 aatctactaa ttttagtgct gcttcatacg tttcaaatga tttatttcta ttatcttcga
    12541 accattgctc aattacatgt ttcactgaag caattgtttc atgatcatac caatctgttt
    12601 gaaaagcgtt acattccccg aaatatgcat ttcctttgtc atcaatcaat tcgataaaca
    12661 aacaatcacg atgcgttaaa gtgactttcg gtgttacaat ttgtgactta aatggctcac
    12721 tatatttata aaaatgcaaa gctgtcaact tcatcaaatc atcctctata caacttattt
    12781 ctctgtaatt tacccgttga tgtataaggt aaagtatcaa ccttttcaaa gtgtttcggt
    12841 actttatatt tcgctaaatg ttttgataaa tatgcaatca attgtgcctt tgaaatgtca
    12901 ctttcactga caaaatataa tttaggcact tggccccaag tatcatcagg atgccctaca
    12961 catactgcgt cactgatacc tggaaattgc ttcgctaccg tttcaatttg atatggataa
    13021 atattttcac cgccactaat aattaaatct ttacgtcggt cataaatcat aacataacct
    13081 tcatgatcta tttcagcaat gtcacctgta ttaaaataac cattttcaaa cgtacccgtt
    13141 aaatctgttg gatacaaata tccattcatc acattggcac ctttaatcat taattctcca
    13201 tgaccttctt tattaggatt tttaatttta acgtcaacat tggcacttgg catccctaca
    13261 gtgtcaggac gtgcatgcaa catttccggt gttgctgtta aaaattgcga acatgtctca
    13321 gtcataccaa atgaattata aattggcagg ttatattgta atgccgtctc tatcatagtg
    13381 gcagataatt tagcaccgcc gagtaatatt ttttgtaaat tataaggttc atgtaaacct
    13441 tgttgcataa gccaatttaa agtttgtggc acaagcgaaa tgtgcgtgat tcgttcattt
    13501 ttaatcatcg ttaaaatttg ttcggcattg aatttatcaa caatgcgcac agtaaaacct
    13561 tcaataacag ctcttaaaag tacactgaga cccgaaatat gataaatcgg caagacagat
    13621 agccaattag tgtcacgatc aaatcccaag ctctctttac atccgattgc actggcataa
    13681 tgattacgaa acgtttgtgg caccgctttt tgagggcccg ttgtccctga tgtaaacata
    13741 attgatgcaa tgtcatctaa attaaatgat gtatttaata tgttggacgg cgactctttc
    13801 ggcaccacag tttcattcga tgtatcatat tggataccca ttgtgttgtc caacaaaccg
    13861 ttcgttgtaa tatcccttcc agcgaattca atatcatcca gcgatacaat ttgaaaccct
    13921 cgcaattcca gtggcaaggt acaaaaaatc aattgtacat cgattgacct catctgattc
    13981 gtcatctcat taggtgtcaa ccttgtatta atcatcgcaa tttcaatatt tgccaaccaa
    14041 catgcatgta ttaaaatgat cgattgaatc gaattatcta tgtatagccc gacacgagat
    14101 tgttgataag ccttgagtct tttagccaat agactcgctt cacagtataa attttgataa
    14161 gtataagatt cttgaccgtc tgttatcgca atatgatgtc cattttgttg tgcttgttta
    14221 tataaccaaa agtccatgcg ttattcctcc aaaatcattt acattataat tataacgatt
    14281 ttatgacatt ctagcagtgg ttatgtttaa aaatataaaa aagtagacga attgattcat
    14341 tgatatgatt gttataatgc tcaatacata tcgttatatc attcgtctac tattatcagt
    14401 tatttttatt taattttagt gtcattctgt cattttgatg tggtgattta cccattgttg
    14461 ccacatcatc tgcaatgtca attggtatac gattcatgtc ttgtaatgca cttaaatgga
    14521 atacttcatc atctaaattt tcaatgagat atacataata tgttaccttg tcctttttat
    14581 attttaacgt tttccaaaag tccggcttgc aattcaatac attatccgga atatattcaa
    14641 taaataagta acgtttgctg cctactttgt ctatgaaata ttttgcagtg cctttttcta
    14701 tacctcttat atgtgcatag tctgctgaaa agtaaatact acctattgtt tcattatgtt
    14761 gttgtatttc aaatcgttgg cctactattt tattatttgt gccacaacta cttaaaaaaa
    14821 tcagtagata tagcattaaa catattttca tccccttgaa ttttaaaaac tttttcaaaa
    14881 gcaacacctc taaaaataaa tacaatatat tatagcaaat agaaattatt attttgttaa
    14941 attatgttgt catgttcgtg tcattttgag tcgtaataca actttacaat tattaaatta
    15001 acacttctac aatccaaaaa t
//
LOCUS       DAPDIM010000062        14968 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000062 DAPDIM010000000
VERSION     DAPDIM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 14968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14968
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.062"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            19..414
                     /locus_tag="RFE25_002182"
     CDS             19..414
                     /locus_tag="RFE25_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817218.1"
                     /translation="MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQL
                     NLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVAL
                     NPYTTIVSAVLYILTAIATVEATKTKYRN"
     gene            610..1995
                     /gene="fumC"
                     /locus_tag="RFE25_002183"
     CDS             610..1995
                     /gene="fumC"
                     /locus_tag="RFE25_002183"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HDU2817219.1"
                     /translation="MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVV
                     YGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSN
                     MNVNEVVSYVANMYLKDHQIDESIHPNDDVNESQSSNDTFPTAMHVALYQEVETKLEP
                     ALKLLRNTLKEKEDKFESIIKIGRTHLQDATPIKLGQEISGWRYMLDRCEIMLSESKK
                     HILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLH
                     GTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMV
                     AVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPI
                     EENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEA
                     WIKPEDMVDPH"
     gene            complement(2448..3269)
                     /locus_tag="RFE25_002184"
     CDS             complement(2448..3269)
                     /locus_tag="RFE25_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDU2817220.1"
                     /translation="MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPA
                     RLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKES
                     NTLMNHVIYTIDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKAN
                     VKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKEAVCQLEIKLDT
                     GRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD"
     gene            3432..4544
                     /locus_tag="RFE25_002185"
     CDS             3432..4544
                     /locus_tag="RFE25_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing sensor histidine kinase"
                     /protein_id="HDU2817221.1"
                     /translation="MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGW
                     IFFINSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRI
                     NLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLG
                     SAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQA
                     FKTIEKTSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSN
                     EIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASS
                     HGINNIKQRVKLLRGKVTFHSQPTKGTQIQFTIPIK"
     gene            4566..5189
                     /locus_tag="RFE25_002186"
     CDS             4566..5189
                     /locus_tag="RFE25_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2817222.1"
                     /translation="MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLK
                     EHEHPDIVLLDLVMPGMNGIEITEYIKAHYPEIKVLVLTSYVDDEHVISAINKGADGY
                     EMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
                     GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI"
     gene            5545..6009
                     /locus_tag="RFE25_002187"
     CDS             5545..6009
                     /locus_tag="RFE25_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817223.1"
                     /translation="MDRQSFTDLIQTKFKMVRIEAGYTQDTMAQTIGLSKKTLVQIEK
                     ERVLPNWTTCISICALFRDSEVLNSTFGCDPLEIVQTISRNHCAYPNHAPTSDIYWNN
                     IETRNGYILQSNKVSNIYRVLNPDNQPIFGTSKMREAETYFNRNAKEELVHI"
     gene            6188..7312
                     /locus_tag="RFE25_002188"
     CDS             6188..7312
                     /locus_tag="RFE25_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HDU2817224.1"
                     /translation="MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVP
                     FTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKLTKD
                     QLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLDQH
                     VDNATDLLCDRARNYLSSAKGTQDINDMLDTFFHEKGKLIGMLQMFMTKESIADRIQQ
                     ELIRLTSHPKARTIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYVTTYASNQ
                     ANKPVVTLMPQFVDYLEGQLSSKLANLIIEKLSIHLSTIMKKVDLRGLIEEQINTFDL
                     DYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV"
     gene            7381..7725
                     /locus_tag="RFE25_002189"
     CDS             7381..7725
                     /locus_tag="RFE25_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HDU2817225.1"
                     /translation="MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDE
                     FRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQ
                     IIVKPLDEIYAD"
     gene            8264..8362
                     /locus_tag="RFE25_002190"
     CDS             8264..8362
                     /locus_tag="RFE25_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817226.1"
                     /translation="MSVGSLAVLTITEIAFPTEIFEKNQRTLQIKF"
     gene            8653..9849
                     /locus_tag="RFE25_002191"
     CDS             8653..9849
                     /locus_tag="RFE25_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDU2817227.1"
                     /translation="MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDI
                     ALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKIS
                     SNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHI
                     GVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGR
                     HFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQV
                     REEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDES
                     PLVNEFSAELLVDQTVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMR
                     GEQNDN"
     gene            9839..12775
                     /locus_tag="RFE25_002192"
     CDS             9839..12775
                     /locus_tag="RFE25_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDU2817228.1"
                     /translation="MIIKSLEIYGYGQFVQRKIEFNKNFTEIFGENEAGKSTIQAFIH
                     SILFGFPTKKSKEPRLEPRLGNQYGGKLVLILDDGLEIEVERIKGSAQGDVKVYLPNG
                     AVRDDAWLQKKLNYISKKTYQGIFSFDVLGLQDIHRNLNEKQLQDYLLQAGALGSTEF
                     TSMREVINRKKDELYKKSGKNPIINQQIEQLKQLESQIREEEAKLETYHRLVDDRDKS
                     SRRLENLKHNLNQLSKMHEEKQKEVALHDHSQEWKSLEQQLNIEPITFPEKGVDRYEK
                     ARAHKQSLERDIGLRNERLAQLKEEATQLEPVKQSDIDAFISLNQQENEIKNKEFELT
                     AIEKDIANKQRDKDELQANIGWSETHHDVDSSEAMKSYVSEQIKNKQEQAAYIKQLER
                     SLEENKIEDNAVHSELDSVEEKIVPEETFEKKKEYSQQVIELNEKENLYSKLKERFEI
                     EQQEKQKRQKLLRTTFILLTLVGIGLTAFSFISNNMLFGIIFAVLTLVFVIGIIMSKS
                     KEVDYSEAITDEIEEIKAQLAILDENYDLDFDLDEQYRIRDHWQQALKNKDILEEKRQ
                     YIEGRLNDAKGRHDELQSTVENVKDELYLSSKISNDLIVDSISTMANIKALDQHISDL
                     NQQRQQLVQELDTFYNHAEAVTKSQFVYFNKLSLFHDVQQWLKSAEDTNEKWRINAEN
                     TKLVTNELNHLNAQLEENNKEITALFDFINVGTEEDFYQHHEDYQTYTSNLSRFNDLT
                     KYLENQNYSYELSSSLSEKTTAQLEEEDHLLATQVDEYNEQYLEMQAQVSDLSAQINH
                     METDTTLANLRHEYHSLKNQLNDIAKDWASLSYLQSLVDEHIKQIKDKRLPQVINEAV
                     EILKHLTDGRYTMINYNEDSITVKHVNGQLYDPVELSQSTKELLYVALRISLIKVLRP
                     YYPFPLIVDDAFVHFDKKRTEKMLNYLRSLSEHYQVLYFTCVKDNIVPSKEVITLNKI
                     EEGGKR"
     gene            12772..13713
                     /gene="yhaM"
                     /locus_tag="RFE25_002193"
     CDS             12772..13713
                     /gene="yhaM"
                     /locus_tag="RFE25_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM"
                     /protein_id="HDU2817229.1"
                     /translation="MRNIENLNPGDSVDHFFLVHKATQGVTAQGKDYMTLHLQDKSGE
                     IEAKFWTATKNDMATIKPEEIVHVKGDIINYRGNKQMKVNQIRLATTEDQLKTEQFVD
                     GAPLSPAEIQEEISHYLLDIENANLQRITRHLLKKYQERFYTYPAASSHHHNFASGLS
                     YHVLTMLRIAKSICDIYPLLNKSLLYSGIILHDIGKVRELSGPVATSYTVEGNLLGHI
                     SIASDEVVEAARELNIEGEEIMLLRHMILSHHGKLEYGSPKLPYLKEAEILCYIDNID
                     ARMNMFEKAYKKTDKGQFTDKIFGLENRRFYNPESLD"
     gene            complement(13834..14796)
                     /locus_tag="RFE25_002194"
     CDS             complement(13834..14796)
                     /locus_tag="RFE25_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HDU2817230.1"
                     /translation="MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVA
                     DTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKAL
                     QQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
                     LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEK
                     ALFKLKDGEVSEVVKSSFGYHIIKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAY
                     KDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ"
BASE COUNT         5502 a         2137 c         2577 g         4752 t
ORIGIN      
        1 gaggagattt atatatttat gttaggaaaa tactggattc aattattgat agcaacagtt
       61 attataagtt taatatcaat taaagctttt ccattggcaa ttggggcatt atatttacct
      121 gttattttca aagtaataaa attacaactc aatttatcaa aaggattaat cgatgatgtt
      181 aatgcgcaaa cattcattaa aagtaatcaa tcaggtattg taataagtgt aatttgttgt
      241 ttattaataa caggaatatt gtattataca cttgatgggt tttatgcgag tttaacagga
      301 gttttaggta cgcttgttgc tctaaatcca tatacgacaa ttgttagtgc tgtattatat
      361 atacttacag ctattgctac ggttgaagct actaaaacaa agtatcgtaa ttaaacttag
      421 ttcaacaata actaaataat gatagataac acactaatcg tatgaccgta tcactgtaat
      481 aaagggtgag tacgtgcgat tagtgtattt ttatttcaaa ttatgaaaac gttttaatca
      541 taaattgctc aattaaatta tttaatgata tactacagtt aaataaacag tgataagggg
      601 agaaattgaa tgtcagtaag aattgaacat gatacttttg gagaaataga agtacctgca
      661 gataaatatt ggggtgctca aacagaaaga agtaaacgca atttcccagt tggtaaagag
      721 cgtatgccaa tcgaagtagt ttatggtttt gcacaactaa agcgtgcagc agcattagct
      781 aattttgatt taggaaaatt aagcgaggca aagaaagatg ccattgtata cgcatgtgat
      841 caaattttat caggtgaatt agatgaacac ttcccactag ttgtatggca aacaggaagc
      901 ggtacacaaa gtaatatgaa tgtgaacgaa gtagtaagtt atgttgctaa tatgtattta
      961 aaagatcatc aaattgatga aagtatccac ccaaatgatg atgtaaatga atcacaaagt
     1021 tcgaatgata cattcccaac tgctatgcac gttgcattat atcaagaggt tgaaacaaaa
     1081 ttagaacctg cattaaaact tttaagaaat actttgaaag aaaaagaaga caaatttgaa
     1141 tcaattatta aaattggtcg tacacattta caagatgcaa cgccgatcaa actaggacaa
     1201 gagattagtg gctggcgtta tatgcttgac cgttgcgaaa taatgttatc tgaatctaag
     1261 aagcacattt taaatcttgc catcggtggt acggctgttg gtactggtat taatgcgcat
     1321 cctgaatttg gtgataaggt ggcacattat atttcagaaa atacgggtta tccatttgta
     1381 tcttctgaaa ataaattcca cgcacttaca gcgcatgatg aagttgttca attgcacgga
     1441 acattgaagg cattagctgg agatttaatg aaaattgcta atgatgtgag atggttggct
     1501 tcaggtccac gagctggttt ggcagaaatt tccatccctg aaaatgaacc aggttcatca
     1561 attatgcctg gtaaagttaa tcctacacaa tgtgaaatgt taacaatggt tgcagtccaa
     1621 gtaatgggta atgatacagt tgttggcttc gcaagttcac aaggtaactt tgaattgaat
     1681 gtttataaac cagttattat gcataataca ctacaatcaa tttacctttt agctgatggt
     1741 atggaaacat ttaataacaa ttgtgcagtg ggcattgagc caatcgaaga gaatattgat
     1801 aattatttaa atcaatcatt aatgttagtt actgcattaa atccacatat tggttatgaa
     1861 aaagcagctc aaattgctaa gaaagcccat aaagaaggtt taactttaaa agaatctgca
     1921 attcaaactg gatatgttac agaagaacaa tttgaagcat ggattaaacc agaagatatg
     1981 gtagatcctc attaattaaa tattaatata aaataaagtt tgggcattat agtgttcaag
     2041 ctttattttt tgtctatgtc aaattgaact tataagtccg atttgatata gagccatgaa
     2101 aaggaaaaac ttttcatgga gtccgtttta ttatagaacc tattttttat atgatgaatt
     2161 gttgtacatg tattggccaa acaacctgtg ataaaaatct tatgatgtca tgtattgtcc
     2221 atagatacac gtaacgcagt tgaaaaagac tacaagtcat tatccaagga tgttataaaa
     2281 tgaataattg ctaaaatatc aaaatataaa atcctaagca tcgtaaaaaa caaaaaaacc
     2341 gaacatctga aaaaattaat aattttccat ctatccgatt taagttgata cttgatttag
     2401 ttacaatgcg gtattgcatg tttaaatatc atgcaaaact aatcaaatta gtcatccaaa
     2461 gaaacggaaa tgacttcctt agtcaaggga tgcacaaact ctattttgta actttcaagt
     2521 tctaattgtc ttaacgttga atcaccatat aaaggatcac caataacagg gtgaccaatt
     2581 tcagctaaat gcacacgaat ttgatgagta cgtccagtat ccaacttgat ttcaagttgg
     2641 cacacagctt cttttatcat ttttgaagtt aaaatgtgtg taattgcacg ctgtccagta
     2701 ggagacacac gtcgtttatt cgaatggaat ttatctttac caattggcat atcaatcgtt
     2761 tgtggtttta aaggtaaaag tgccttaaca tttgctttgt atatccgcgt aatatcattg
     2821 tcttctaaca tgcgatcaag aatttttttc attaaaggat ttttagcaac aattaataat
     2881 cctactgttt cctggtccag tcgatgaatt ggttcgacat agtcactatc aatagtgtaa
     2941 atcacatgat tcattaaagt attgctttct tttaaatcat tagggtgagt cttaacacct
     3001 ttaggtttca ttacgattgc catatcatcg tcttcgtatt taatttgtgc ataacgataa
     3061 cttggaacat aattactttt ttcatcgatg gttggaacaa atacatcgtc gccagtatgc
     3121 actttatcca ttaatcgcgc aggtttatca ttaatagtaa tatctttaga catatttaaa
     3181 tgatgtaaat cttttttagg taccttaagt tgttggaaaa tatctcgtaa acttaagtca
     3241 ttaaagtttt ctggtatttt aaatttcata aaatcctcct atagtcttta atatcatatc
     3301 acaaatcagt tctcctaaat ataactattg agtaatcaag gccattttat catgttcacg
     3361 tctaagattt aaaaatataa taactcaatg tataatagtt aatacacgta aaaatgaatt
     3421 ggagcgattt gatggaacaa aggacgcgac tagctttatt aaaagagatt gccgaatttt
     3481 taaacgaaga aactgaaatg tatagcatga cccaaggtgc gttaaaatat ttaattgagg
     3541 gcagtaattt cacgacaggc tggatatttt tcatcaatag cgtaggtgaa catgaacttg
     3601 tatcacatgt ggctctacca caatctttga cagcagacca ctgtcactat attaaagatg
     3661 ggtcttgttg gtgtgtgaaa gcatttaatc aacgtaggct aatgaaagcg tcgaatatcg
     3721 tcaattgttc tcgtattaac ttagcctcta aagcatttcc tagccaaaat gacaatatta
     3781 cacatcatgc aacggtacca cttaaatcgg gtcaagaaca attcggcatt ttaaatgtag
     3841 cgtccccaaa tactgaaata tatagtgatg aagatttaga gttgctagag tctgtcgcat
     3901 ttcaattagg gtcagccatc aaacgtattt atttaacaga ccgtgaaaaa gaagcagcaa
     3961 aaattaatga acgtaatcgt ttagctagag atttacatga ttcagtaaat caaatgttat
     4021 tttctgtaaa actaacagca catgctgcgt atggcatgtc aaacgaatcc atcgctaaac
     4081 aagcattcaa gacgattgag aaaacgagtc aaaatgccgt taatgaaatg cgtgcattga
     4141 tttggcaact taagccagtt ggacttgagc aaggtttaat tcatgctttg acagcatata
     4201 gtaaattaat gcatatacaa ttaaatgtaa atgtagaagg tttaatcgat ttatctaatg
     4261 aaatcgaaga aaacatatat agagcattac aagagtgtat taataatgtt aagaaacatg
     4321 ctgatacgaa taaaatggat cttacattaa aacaaatgaa cgatatacta tatattgacg
     4381 tgattgatta tggtcaagga tttgagatcg ataatgttca gatagcttca tcacacggta
     4441 ttaataacat aaaacaaaga gttaaattat taagaggtaa agtgaccttt cattctcagc
     4501 caacaaaggg tacacaaata caattcacaa ttcctataaa atagcttgat ttaaggagat
     4561 aacccatgaa caaagtaata ttagtagatg accattatat tgtgcgacaa ggattgcgat
     4621 ttttattatc cacgattgaa aacatagaag ttttacaaga ctttgcagat ggagaaacat
     4681 ttttagaata tttaaaagag catgagcacc ctgatattgt gctattagat ttagtgatgc
     4741 ctggcatgaa tggtattgaa attacggaat atattaaggc acattatccg gaaattaaag
     4801 ttttggtatt aacaagttat gttgatgatg aacatgtaat ttcagcaatc aataaaggtg
     4861 ctgatggtta tgaaatgaaa gacgttgagc ctcagcaatt aattgaaact attagacgag
     4921 ttatgaacgg tgaaaaaatg atacatccta aggcacaaga tgtattcgaa acagttagcc
     4981 aaaaaccaca ctacacgaat aagttgtcaa agagagaaat tgaagtgtta cgtgaaatgg
     5041 ttaaaggtaa aacaaataaa gagattgcag aaactttatt tgtatctgaa aaaacaatta
     5101 aaacacatgt cagtcatata tttagtaaat tacaagttag cgatcgtaca caagcagcaa
     5161 tttatgcaat ggaaaataag ttgatttaga atgagctttt aaatatttgt cgaaaaatag
     5221 acaattttta atctgatttt gatgaatttt ttatagcgat agggtttatt atacagtttt
     5281 ctttgtaaat ttgatatcat tataaaagtg taagttttat caaatctagt gattgtgcat
     5341 aaaattttac ttcatttact ttcgcttcat tataaagtaa acttaactct tgttgacttg
     5401 atcaaaattt aatacaaatg tgaaattgac tcttttcatt ttattaaaaa tatattaaga
     5461 tgtaatctgt gtttcaagaa atgtgtatta ttgcaatttc ttgtgtccgg ataaaattcc
     5521 ccaaacagaa aggtagataa cagaatggat agacagagtt ttacagattt aattcaaaca
     5581 aaatttaaaa tggttcgtat agaggctggt tatacgcaag atactatggc gcaaacaatt
     5641 ggactttcta aaaagacttt agtacaaatc gaaaaagaga gagtattacc aaactggaca
     5701 acttgtattt caatttgtgc attattcaga gactctgaag tattaaacag tacatttggc
     5761 tgtgatccat tagaaatcgt tcaaacaatt tcaagaaatc actgtgcata tccaaaccat
     5821 gcaccaacaa gtgatattta ttggaataac attgagactc gtaatgggta cattttacaa
     5881 agtaacaaag taagcaatat ttatcgtgta ttaaatccag ataaccaacc aattttcggt
     5941 acttctaaaa tgagagaagc tgaaacatac tttaacagaa atgctaaaga agaattagta
     6001 catatctagg cctatatact tttaataaat aataaaagcg atgtaacaca cctgtttcga
     6061 gaggtgaggc atcgcttttt gtatgtaaac taataataaa ttgagcagaa agtgaaatga
     6121 ttaatgaatt aaaaaataaa aatagtggta taatgaataa ctatgttgtc acaaaggagt
     6181 caaaattatg aatgcactat ttattatcat atttatgatt gtagtagggg cgataattgg
     6241 gggcattact aatgtaattg caattagaat gctgtttcac ccctttaaac catactatat
     6301 atttaaattt agagtcccat ttacaccagg tttaataccg aaaagacgcg aagaaattgc
     6361 aactaaaatt ggccaagtga ttgaagagca tttgcttaca gaaactttaa ttaatgaaaa
     6421 attaaaaagc gagcaatcac agcaagcaat agaatctatg attcaacagc agttacaaaa
     6481 gttgacgaaa gatcaattgt caataaaaca aattacttct caaatcgata ttgatttaga
     6541 acaagtatta caaactaatg gaaatcaata tattgaatca caattgaata attattatac
     6601 aaagcatcaa aaccaaacaa tagcatcttt attgccaaat caacttgtaa catttttaga
     6661 tcagcatgta gataacgcaa cagacttatt atgtgatcgt gcaaggaatt atttatcatc
     6721 tgcaaaaggc acacaagata ttaatgatat gttggatact tttttccatg agaaaggtaa
     6781 gttaattggt atgttgcaaa tgtttatgac aaaagagagc attgcagatc gcattcaaca
     6841 agaacttata cgtttaacat ctcatcctaa agcaagaaca attgtgacat cgttaattac
     6901 caatgaatat caaactttta aagataaacc attgaatgaa ctgttagatg catcgcagtt
     6961 taatgaaatc gctgaaaatc tatcagtgta tgtaacaaca tatgcaagca atcaagcgaa
     7021 taagccagtg gttacgttaa tgcctcaatt cgttgattat ttagaaggtc aactctctag
     7081 caaattagca aatttaatca ttgaaaaatt atcgattcac ttatctacaa ttatgaaaaa
     7141 agtggattta cgaggattaa ttgaagaaca aattaatacg tttgacttag attatattga
     7201 aaaattaatt atagaaattg ctaacaaaga actaaagttg attatgtcat taggtttcat
     7261 tttaggtggt attattggat ttttccaagg tttggttgca atctttgtct aaaaaagcga
     7321 gatgtggtaa agtaatatcg aacgttttaa taaacatcac aacaaaggag tgctataacc
     7381 atggcagtaa atttatatga ttatgcaaat caattagaac aagctttaag agaaagcgaa
     7441 gaatacaaag caatcaaaga agcattcgct aatgtaaaag ctaacgaaga atctaaaaag
     7501 ttattcgatg agttccgtga aactcaaatt aacttccaac aaaaacaaat gcaaggtgaa
     7561 gaaattgctg aagaagattt acaaaaagcg caagaacaag cgcaagcaat tgaaaaagat
     7621 gaaaacatct ctgcattaat gaatgctgaa caaaaaatga gtcaagtatt ccaagaaatc
     7681 aaccaaatta tcgttaaacc attagacgaa atttacgctg actaatatta aaataatatt
     7741 tttcaatcct ttaaatagag gaatagactg ccgacagagt ccgagacttt gtgggtagtt
     7801 tttttagttt tgataacgga agttagaggc tctctgtcaa attgggcaga tgcgttcact
     7861 atcggaattt aggctactaa acatgtccta gctttagctc agaatggacg acggaagctg
     7921 ggcaatcaaa catggctagc tctatgccaa aacgggcaga tgagcttgat aacggaagtt
     7981 agaggttcta tgtcaaattg ggcagatgca ttcagtaacg gaagttaggc tagtaaacgt
     8041 gtcctaactt cctttttgca ttttgaagtg taaagttttc aacataatac tattagttcg
     8101 gtcatgtatc ggactgatgg aaaagcgttt cacttttaat gactcattaa gaacggcctg
     8161 aaaatgtttg gcgtattaag tgcaatgata gttttgacat ttagtttcta attggtcatt
     8221 actgccgagc aaatctagta gagtaatcat gtaaatcttt aatgtgtcag ttggttcact
     8281 agcggtgtta acaattacgg aaattgcatt tccgactgaa atttttgaaa aaaatcaacg
     8341 cacgctacaa ataaaatttt aaactgttat aaatgtgtct caatttcata tgttcatcga
     8401 cgatatgaag cgtattatgg taaaatgaag aaataataaa cttgttaata aataaaacat
     8461 cacgatttga ctaaagcact ttattattgt gtagataata attttttaac gaaataaaaa
     8521 tggcgactgg ttttaataaa tcagctaatg aatcactaca cctataagta tgaatatagt
     8581 gattagaatg ctttgtatag ttggattttg caaaattgat gttagaacct ttaattaagg
     8641 agatatggat gtatggttaa atttattcat tgttcggatt tacatttaga tagtcctttc
     8701 aaatctaaga gtcatataag ccctaaaatt tttgaggatg ttcaaaaaag tgcttatgaa
     8761 agttttaaaa atattgtaga tattgcatta caacaagatg ttgattttgt aattatcgcg
     8821 ggtgatttat ttgatagtga aaacagaaca ttacgtgctg aaattttctt aaaacagcaa
     8881 tttgaacgtt tacaaaatga acaaatcttt gtttatgttt gtcatggtaa tcacgatcct
     8941 ttatcatcaa agatttcatc aaactggcca gataatgttt ctgtattttc aaataaagtt
     9001 gagacgtatg aagcaattac taaatctggt gaaacaattt atattcacgg atttagttat
     9061 gaaaatagag caagttatga gaacaagatt gatgaatatc catcaagtca aggccaaaaa
     9121 ggcatacata ttggtgtctt gcatggtacg tatagtaaat cttcagttaa cgaaagatat
     9181 accgagttca ttttagaaga tttaaacagt aaattgtatc attattgggc tttaggtcat
     9241 atacatgaac gtcaacaatt aagtgatatg cctgtaatta actattcagg taatattcaa
     9301 ggtagacatt ttaatgagca aggtgaaaaa ggttgcttat taatcgaggg tgaccactta
     9361 aaattaaaga ctaaatttta tcctacacag tatattagat ttgaagaagc aactattgaa
     9421 acggataaga catctaagca aggtttatac gaggtcattc aaaactttaa agaacaagtg
     9481 agagaagaag gaaaagcctt ttatcgttta acgcttgtta ttaatagtga gacattaatt
     9541 tcacctcaag atttattaca agttgaagaa atgattacag attatgaaga aaacgaaaat
     9601 caatttgtat atattgatga gttaaaaata caatatgcac aaaatgatga gtcaccttta
     9661 gttaatgaat tttcagcgga attattagtc gatcaaactg tttttgataa agcgatgtca
     9721 gatttatatt taaatccaag ggcatctaag ttcctagacg attatggaac attcgaccat
     9781 acagcattag ttaatcgtgc tgaagaaata ttaaaagctg aaatgagagg tgaacaaaat
     9841 gataattaaa tcacttgaaa tttatggtta cggtcaattt gttcaacgta aaattgaatt
     9901 taataaaaac ttcactgaaa tttttggtga aaatgaagcg ggtaaatcga cgattcaagc
     9961 attcatccat tcgatattat ttggttttcc aactaaaaag tctaaagagc caagactaga
    10021 accacgtcta ggtaaccaat acggtggtaa attagtactt attcttgatg atggcttaga
    10081 gattgaagtt gaacgaatta aaggcagtgc tcaaggtgat gtgaaagtat atttacctaa
    10141 tggtgctgtg cgtgatgatg cttggttaca aaagaaactt aattatattt ctaaaaagac
    10201 atatcaaggt atcttttcat ttgatgtact agggcttcaa gacattcata gaaatctaaa
    10261 tgaaaaacaa ttgcaagatt atttattaca agcaggggct ttaggatcaa ctgaattcac
    10321 gtcaatgcgc gaagtgatta atcgtaaaaa agatgaatta tataaaaaat caggtaaaaa
    10381 tccgatcatt aatcaacaaa ttgagcaatt aaaacaacta gaaagtcaaa ttcgtgaaga
    10441 agaagcaaag ctagaaacat atcatcgctt agtagatgat cgagataaat catcacgtcg
    10501 attagagaat ttaaagcata atttaaatca attatcaaaa atgcatgaag aaaaacaaaa
    10561 agaggttgct ttacatgatc attcacaaga atggaagtct ctagaacaac agttaaatat
    10621 tgagccaatc acattcccag aaaaaggtgt ggatcgttac gaaaaagcgc gagcgcataa
    10681 gcaatcgtta gaaagagata ttggtttaag aaatgagcgt ttagctcaac ttaaagaaga
    10741 agcgactcaa ttagagccag ttaaacaatc tgatattgac gccttcatta gtttgaatca
    10801 acaagaaaat gaaattaaaa ataaagaatt tgaacttact gcaatcgaaa aggatattgc
    10861 gaataaacaa cgtgataaag atgaattgca agcaaatatt ggttggtctg aaacgcatca
    10921 tgacgtagat agttcagagg caatgaaaag ttatgtcagt gagcaaatca agaataaaca
    10981 agaacaagct gcatacatta aacaattaga acgtagttta gaagaaaata aaatcgaaga
    11041 taatgcggtt catagcgaac tagattctgt tgaagaaaaa atagttcctg aagagacttt
    11101 tgaaaagaaa aaagaatact cacaacaagt cattgaatta aacgaaaaag agaacttgta
    11161 tagcaaattg aaagaacgtt tcgaaattga gcaacaagaa aaacaaaaac gtcaaaaatt
    11221 gttacgaaca acgtttattc ttttaacatt agtaggtatt ggtttaactg ccttctcatt
    11281 tatttcaaac aacatgttgt ttggtattat tttcgcagta ttaactttag tatttgttat
    11341 cggtatcatc atgtctaaat caaaagaagt agattatagc gaggccatca cagatgaaat
    11401 cgaagaaatt aaagcacaac tagccatttt agatgaaaat tatgacttag attttgatct
    11461 tgatgagcaa tatcgcattc gtgatcactg gcaacaagct ttaaaaaata aagatatttt
    11521 agaagagaaa cgtcagtata ttgaaggtcg tttaaatgat gcgaaagggc gtcatgatga
    11581 attacaatcg acagttgaga acgttaagga tgaattatac ttatcatcta aaatttcaaa
    11641 tgatttaatt gttgatagta tttctacaat ggcgaatatt aaagcattag atcaacatat
    11701 cagtgattta aatcaacaac gccagcaatt ggttcaagaa ttagatacat tctacaatca
    11761 tgctgaagct gttacaaaat cacaatttgt ttatttcaac aaattatctt tattccacga
    11821 tgtgcaacaa tggttgaaat cagctgaaga cacgaatgaa aaatggcgta ttaatgctga
    11881 aaataccaaa cttgttacaa atgaattaaa tcatttaaat gctcaattag aagaaaataa
    11941 taaagaaatt acagcactat tcgattttat caatgttggt actgaagaag atttttacca
    12001 acatcatgaa gattaccaaa cttatactag taatttgagt cgttttaatg atttaactaa
    12061 atatcttgag aaccaaaact attcttatga attaagttct agtttaagtg aaaaaacaac
    12121 tgcacaactt gaagaagaag atcatttatt ggctactcaa gttgacgaat ataatgagca
    12181 atatcttgaa atgcaagcac aagtcagtga tttaagtgca caaatcaatc acatggaaac
    12241 tgatacaacg cttgctaatt taagacatga atatcacagt cttaaaaatc aacttaatga
    12301 tatcgcaaaa gattgggcaa gtttaagtta tttacaaagt ttagttgatg aacacattaa
    12361 acaaattaaa gataaacgtt tgcctcaagt tattaatgaa gcggtagaaa tattgaagca
    12421 tttaacagat ggcagatata cgatgattaa ctataatgaa gattcaatta cggttaaaca
    12481 tgttaatggt caattatatg atcctgttga actaagtcaa tctacaaaag aattacttta
    12541 tgtagcttta cgtatcagtt taattaaggt actaagacca tattatccgt tcccattaat
    12601 tgttgatgat gcatttgttc attttgataa aaagcgtact gaaaaaatgt tgaattattt
    12661 acgatcatta tcagaacact atcaagtact atactttaca tgtgtaaaag ataatattgt
    12721 tccatcaaaa gaagtgatta cattaaacaa aatagaggaa ggcgggaaac gatgagaaat
    12781 atagagaatc taaatcccgg agattcagtt gatcactttt tcttagtgca taaagctaca
    12841 cagggtgtaa cagcacaagg taaagattat atgacattac atttgcaaga taaaagtggt
    12901 gaaattgaag cgaaattttg gacggctaca aaaaatgata tggcaacaat caagcctgaa
    12961 gaaattgtac atgttaaagg tgacatcata aactatcgcg gaaataaaca gatgaaagtc
    13021 aaccaaatta gactagcgac aactgaagat caattaaaaa cagaacaatt tgtagatggt
    13081 gcacctttat caccggcaga aatacaagaa gagatttctc attatttgct agatattgaa
    13141 aatgctaatt tacaacgtat cacacgtcat ttattgaaaa aatatcaaga acgattttac
    13201 acatatccag ctgctagttc tcatcatcat aactttgcga gtggcttaag ctatcatgta
    13261 ttgacgatgt tacgtattgc aaaatcaatt tgtgacattt atccattgtt aaacaaaagt
    13321 ttgttatata gtggtattat tttgcatgat attggtaaag ttagagaatt gagtggtcct
    13381 gttgcgacgt cgtatacagt cgaaggtaac ttattaggac acatctcgat tgcgagtgat
    13441 gaagtagttg aagcagctcg tgaattgaac attgaaggag aagaaatcat gttgttaaga
    13501 catatgattt tatctcatca tggtaagtta gagtatggtt cgccaaaact gccatactta
    13561 aaagaagcag aaattttatg ctatatcgat aacatcgatg ctagaatgaa tatgtttgaa
    13621 aaggcttata aaaaaactga caagggtcag tttacagata aaatatttgg tcttgaaaat
    13681 cgtagattct acaatcctga atcactcgat taagaattaa aagatatcgg acagatgagt
    13741 atactgaaac atgagctcct ctgtccgatt tttaatgcga aaaaaccgag cggccgtggt
    13801 atgatttttg aaccacggtc gctcggtttt gtgttattgg ctcatgccgg attgtccgcc
    13861 ttgtgcgcca ccttgtttaa gtttttcagg gtttaagatt ttatcttcga caactgattt
    13921 aatatcacga tctttaaagt caacatcgta ttcttttaat agatctttgt atgcatcagt
    13981 taataatttt ggattttttt gtactttctg atcgactaat ttttctttca ggctttgttt
    14041 ttcactgtta aagtctgttg gtttatcagc tttaataata tgatatccaa agcttgattt
    14101 aacaacctct gatacttcac catctttaag cttaaatagt gctttttcaa aatctttatc
    14161 agtttgtcct ttaagaacat aacctaattc gccatctttt ttagctgaac cagtatccat
    14221 tgattctttt ttagcgattt caccaaattt acttggatct tttgaaactt ctttttgaat
    14281 ttcttcagct ttttgtttcg cttctttatc gtctaagcct tctttgtcgc ttttcttaga
    14341 tttaacttta attaaaatgt gtgaagcttt cttgctgtct tctttaattt cagaatcaga
    14401 gattttaatt ttatctgata gtaattcttt atgataagca gcagtacgta aattttcttt
    14461 atatttatcg gctgttaaac cttgctgttg aagggccttt tcaaatttat ctttaccgcc
    14521 gtattgcttt tgcatttttt caatttgttc gtcaatcttc ttatcattaa ctttattttt
    14581 atatttatca gctaaaattt tatttaacat ttcagtaaat gatgcatttg caatttgatc
    14641 tttaccgatt tttttcattg tatctgcaac tgttacatct ccagctttag aagaaattaa
    14701 tgtattttct ttagagtctg tggcactagc gccacaagcg cctaataata aagcactagc
    14761 tgttaccgga acgattaatt tgtttatcat cttcatagtt gaaactcctt tgtaagttaa
    14821 tcatcgtgaa tataacatag ttttatatta tcaccaatca ataacccatg acatcagact
    14881 agagcattag gtttaggggt agaaattgat gaaaataaaa aaacaaggtc tatatacatt
    14941 tgattgtaag ctattacata gcctaaaa
//
LOCUS       DAPDIM010000063        14693 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000063 DAPDIM010000000
VERSION     DAPDIM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 14693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14693
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.063"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(4..171)
                     /locus_tag="RFE25_002195"
     CDS             complement(4..171)
                     /locus_tag="RFE25_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817231.1"
                     /translation="MRYVISIIMGIVLAIWSYKQLSQSHLDSGFIFFFIVYVLCISYF
                     NNDKHDKNKKR"
     gene            complement(283..1827)
                     /gene="pruA"
                     /locus_tag="RFE25_002196"
     CDS             complement(283..1827)
                     /gene="pruA"
                     /locus_tag="RFE25_002196"
                     /EC_number="1.2.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glutamate gamma-semialdehyde dehydrogenase"
                     /protein_id="HDU2817232.1"
                     /translation="MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGE
                     KIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELML
                     RVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDR
                     EGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLM
                     EILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEG
                     QNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYD
                     EVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDS
                     KGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITN
                     NREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQK
                     VVSEMF"
     gene            complement(2017..2616)
                     /locus_tag="RFE25_002197"
     CDS             complement(2017..2616)
                     /locus_tag="RFE25_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDU2817233.1"
                     /translation="MTEKEKMLAEKWYDANFDQDLINERARAKDICFELNHTKPSDTN
                     KRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVF
                     IGPNCGFYTATHPLNFYHRNEGYEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAG
                     SVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK"
     gene            2855..3046
                     /gene="cwrA"
                     /locus_tag="RFE25_002198"
     CDS             2855..3046
                     /gene="cwrA"
                     /locus_tag="RFE25_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall inhibition responsive protein CwrA"
                     /protein_id="HDU2817234.1"
                     /translation="MRILITGTVAILIILGLVKTIQDYEMTNDTSRQLSDNKDDDKVI
                     HLNNFKNLHAKEFNPSDFF"
     gene            3286..5694
                     /locus_tag="RFE25_002199"
     CDS             3286..5694
                     /locus_tag="RFE25_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDU2817235.1"
                     /translation="MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKA
                     TVEYNPDQHDVQEFINTIQHLGYGVTVETVELDITGMTCAACSSRIEKVLNKMNGVQN
                     ATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIK
                     LIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLR
                     NGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLLTLILFGKYLEA
                     RAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKII
                     KGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVE
                     EAQSSKAPIQRLADIISGYFVPIVVGIALLIFIVWITLVTPGTFEPALVASISVLVIA
                     CPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVT
                     DYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDH
                     HHILVGNRKLMADNDISLPKHISDDLTHYERDGKTAMLIAVNYSLTGIIAVADTVKDH
                     AKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQG
                     KKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKAT
                     IRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPR
                     RKDA"
     gene            6232..6438
                     /gene="copZ"
                     /locus_tag="RFE25_002200"
     CDS             6232..6438
                     /gene="copZ"
                     /locus_tag="RFE25_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HDU2817236.1"
                     /translation="MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSV
                     QYDDSKVAVSQMKDAIEDQGYDVV"
     gene            complement(6529..7527)
                     /locus_tag="RFE25_002201"
     CDS             complement(6529..7527)
                     /locus_tag="RFE25_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDU2817237.1"
                     /translation="MTKIKIMSVRDEDMPYIKAWAEKHHVEVDITKEALTDDNVEGVA
                     GYDGLSLSQQIPLSEHVYKRLNELGIKQIAQRSAGFDTYDLELANKYNLIVSNVPSYS
                     PNSIAEFAVNQAINVVRHFNQIQTKVREHDFRWEPTILSKSIKDLKVAVIGTGRIGRV
                     VADIFANGYQSDVVAYDPFPNAKIATYVDYKDTIEEAVEGADIVTLHVPATKYNHYLF
                     NAELFKHFKKGAVFVNCARGSLVDTKALLDALDNGVIKGAALDTYEFERKLFPSDQRG
                     KTPNDPLLESLIDREDVILTPHIAFYTEAAVKNLIVDALDATLDVLQTGDTRLRVN"
     gene            complement(7550..8704)
                     /locus_tag="RFE25_002202"
     CDS             complement(7550..8704)
                     /locus_tag="RFE25_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDU2817238.1"
                     /translation="MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQG
                     IIDHFQKALTIPENQKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGL
                     VAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSTVDSQIID
                     KTKLIYLTYPNNPTGSTATKEVFDEAIAKFKGTDTKIVHDFAYGAFGFDAKNPSILAS
                     ENGKDVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIY
                     ALNHYDDFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQ
                     FLVQEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTELAYLYE"
     gene            complement(9132..10640)
                     /locus_tag="RFE25_002203"
     CDS             complement(9132..10640)
                     /locus_tag="RFE25_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDU2817239.1"
                     /translation="MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKK
                     DGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDL
                     AELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAK
                     LKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIK
                     GGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTA
                     DFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDD
                     FRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSD
                     EALTQQIKEIIYRKLGTIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLA
                     QSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIERGV"
     gene            complement(10652..11515)
                     /locus_tag="RFE25_002204"
     CDS             complement(10652..11515)
                     /locus_tag="RFE25_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="HDU2817240.1"
                     /translation="MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVC
                     RKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQ
                     SFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRL
                     GESLQLINILRDVGEDFDNERVYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAI
                     AEKDFQDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKL
                     FHEINSKYHRI"
     gene            complement(11552..12679)
                     /gene="crtQ"
                     /locus_tag="RFE25_002205"
     CDS             complement(11552..12679)
                     /gene="crtQ"
                     /locus_tag="RFE25_002205"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,4'-diaponeurosporenoate glycosyltransferase"
                     /protein_id="HDU2817241.1"
                     /translation="MKWLSRILTVIVTMSMACGALIFNRRHQLKTKTLNFNHKALTII
                     IPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGK
                     WYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHI
                     TKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANR
                     HIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPK
                     IMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLL
                     MVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ"
     gene            complement(12685..14178)
                     /locus_tag="RFE25_002206"
     CDS             complement(12685..14178)
                     /locus_tag="RFE25_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDU2817242.1"
                     /translation="MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNTHIGGKVNRH
                     ESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYE
                     GIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNA
                     LINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLW
                     YVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIIS
                     NMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAY
                     LNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYA
                     KFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFK
                     FPKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINARETKNRK"
     gene            complement(14171..14659)
                     /gene="crtO"
                     /locus_tag="RFE25_002207"
     CDS             complement(14171..14659)
                     /gene="crtO"
                     /locus_tag="RFE25_002207"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl-4,4'-diaponeurosporenoate
                     acyltransferase"
                     /protein_id="HDU2817243.1"
                     /translation="MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSF
                     NFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAEL
                     IHWISILPVIIFNKGSRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGER
                     HD"
BASE COUNT         4569 a         2896 c         2282 g         4946 t
ORIGIN      
        1 ctactatcgt tttttatttt tatcgtgctt atcgttatta aaataactga tacacaacac
       61 ataaactatg aagaaaaaaa taaatccgct atctaaatga ctttgactca gttgtttata
      121 tgaccaaatt gctaatacaa ttcccattat tattgaaata acgtatctca cattcttata
      181 cctataatcc ttttctaaaa atatggttgc tattacttaa tttttaaagt tataaataaa
      241 aagagccaac cgcaatggat ggcccttgtt cattatgaag cattagaaca tttctgaaac
      301 aaccttttgt tctaagaagt gtaataagta gtctgggcta cctgttttag cgtccgtacc
      361 tgacattttg aaaccaccaa atggatggta tccaacaact gctgaagtac aacctctgtt
      421 aaggtataaa ttacctacat caaattcgtt taccgcttta atccaatgct cgcgattatt
      481 tgtaatcact gcaccagtta aaccgtaatc tgtatcattt gcaacctcaa tggcttcatc
      541 aaaatcgtta actttcacaa agccaacaac tggaccaaaa atttcttctt gcatgattct
      601 atctttagat ttaagtcctg aaatgattgt tggttctaca aagtaacctt ttgaatcatc
      661 agtgccgcca ccttgttcta atttaccttc ttctttacca atctcaatat aatttttaat
      721 cttatcaaat tgttttttat taataactgg gcccatatac gtattgtcta cagtattgcc
      781 caacgttaat tcttttgtta atttgattga tttctctaat acttcgtcat aaacgtcttt
      841 atgcacaatt gcacgtgaac atgcagaaca tttttgacca gagaaaccaa acgctgacgt
      901 tacaatagct tctgccgcca tatctgtatc aatattttca tcaactacaa tggcatcttt
      961 accacccatt tcagcgataa cacgtttcaa gaagttttga ccttcttgaa ctacggcact
     1021 acgttcataa attctagtac ctgtcgcacg tgatcctgta aatgtaacga aatgcgtatc
     1081 tttatgatca actaagtaat caccaatttc tttcggatca ccaggaacaa agttaactac
     1141 gccttttggt aatcctgctt cttctaaaat ttccattaat ttataagcga tataaggtgt
     1201 atcctcagca ggtttcaata acactgtatt acctgcaaca actggtgcta aagtcgtacc
     1261 agccataatc gcaaacggga agttccacgg tggaattgta acacctgtac caattgattt
     1321 atagaaatat ttattgtgtt caccttcacg atcaagtact ggcttacctt gagccaaatc
     1381 catcattgaa cgtgcatagt attcaataaa atcaatacct tcagctgcat caccaactgc
     1441 ttcatcccat ggcttacctg cttcataaac cataattgct gcaatttccg cttttcgacg
     1501 acgaataatt gccgaaacac gtaacataag ctctgcacga tcatttgctg accatgtttt
     1561 ccaagattta taagcttcgt ttgctgcttt aaatgcatct tcaacatctt gttttgttgc
     1621 ctttgatgca tttgcaatca cttgtgatgt gtctgcagga ttgattgatt taattttgtc
     1681 atctttgaaa atcttctctc cattaatcac taatggtatg tcttgaccta attctttttc
     1741 cacgtctttc aatgctttct taaacatatc cacattttct tggactgaaa aatcgtaacc
     1801 aggttcattt ttaaattcta ctaccatgta cacttacccc ctataaattt tgaaagtggt
     1861 ttaacccttt gatttaatga tataacatca tttaaactca ttttactatg attaaggtta
     1921 gttttgcaat cgctttcatt tttatgcttt atcacttatt ctcaagtatt ttgaaattga
     1981 ttggttactt tttaaaattt atatgggtcg caactgctac tttatcgttt cgtcatttaa
     2041 tgtttcggat ggtaggtcat tatcaatttt acgaacgact ttacaagggt ttccaaccgc
     2101 taagctgtgt ggcggaatat ctttagtgac aacactacca gcaccaatca cactgccttc
     2161 tccaatcgtc acccctggta acacggctac atgaccgcca aaccaagtat tactgccaat
     2221 atgaatgggt ccggcttttt cataaccttc atttctatga taaaaattaa gtggatgtgt
     2281 tgctgtgtag aatccacaat taggtcctat aaaaacatta tcgccaattg taatctgtcc
     2341 accatccata aaataacaat tggtgtttac atagacattt tttcctagtt taacgttcca
     2401 accataatct gtatcaaaag gaatcgaaat acttacattg tctgttgttg tttgaaataa
     2461 ttgatcgatt aattcctttc ttttatttgt atcactcggc tttgtatgat ttaattcaaa
     2521 gcaaatatct ttcgctcgtg cacgttcatt gattaagtct tgatcaaagt ttgcatcgta
     2581 ccatttttct gctaacattt tttctttttc agtcattaca cctttcaact cctaataact
     2641 tatttacttg tttaaaagtt aatcaaataa acattcgcct atgcaactaa tacgctataa
     2701 cattatgaaa tcatgacctt atcaccctta tctatacaat tctcgcatca aatactgcta
     2761 aagtagtaga taaattcaat actacagacg cattcatttt ttaatctatt aacgtacaat
     2821 gtgagtaaga gaaatataaa ggagtatgat agcgatgaga atattaatta caggcacagt
     2881 tgctatctta atcattctag gtttagttaa aacgatacaa gattacgaaa tgacaaacga
     2941 tacaagtcgt cagttgtcag acaacaaaga tgatgataaa gtcatccatc ttaataattt
     3001 caaaaattta catgcgaaag aatttaaccc atctgatttc ttttaagtca cctaagaatt
     3061 gcaaatccag aagtcattta agttttacct ttcattcata catcctttaa tattaattac
     3121 gacttctttt atatagatgc taaatagaga gattgttgtg caatgtttgc acggcaatct
     3181 ctctttttct ttttaaaatt ggtaaaagta aaacgcaacg attgacttat atacctagag
     3241 ggggtacatt agacgtgtaa caatgaatca cagggaggca ataatgtggc taatacgaaa
     3301 aaaacaacat tagatatcac tggtatgact tgtgccgcat gttcaaatcg tatcgaaaag
     3361 aaactgaata aacttgatga cgttaatgcc caagtgaatt taactacaga gaaagcaact
     3421 gttgagtata accctgatca acatgatgtc caagaattta ttaatacgat tcaacattta
     3481 ggttacggtg tcactgtaga aactgtcgaa ttagacatta caggtatgac ttgtgctgca
     3541 tgctcaagcc gtattgaaaa agtgttaaat aaaatgaacg gcgttcaaaa tgcaacggtc
     3601 aatttaacaa cagagcaagc taaagttgac tattatcctg aagaaacaga tgctgataaa
     3661 cttgtcactc gcattcaaaa attaggttat gacgcgtcta ttaaagataa caataaagat
     3721 caaacgtcac gcaaagctga agcgctacaa cataaattga ttaagcttat catatcagca
     3781 gtattatctt taccactatt aatgttaatg tttgtgcatc ttttcaatat gcatatacca
     3841 gcactattta cgaatccatg gttccaattt attttagcta cacctgtaca atttattatt
     3901 ggatggcaat tttatgtagg tgcttataaa aacttaagaa atggtggcgc caatatggat
     3961 gtacttgttg ctgttggtac aagtgcagca tatttttaca gtatttatga aatggttcgt
     4021 tggctaaatg gctcaacaac gcaaccgcat ttatactttg aaacaagcgc cgtactactt
     4081 accttaatct tattcggtaa gtatttagaa gctagagcga agtctcaaac aaccaatgcg
     4141 cttggcgaat tattaagttt acaagctaaa gaagcacgca ttttaaaaga tggtaatgaa
     4201 gtgatgattc ctctaaatga agtacatgtt ggagatacac ttatcgttaa accaggtgaa
     4261 aagatacctg ttgatggcaa aattattaaa ggtatgactg ccatcgacga atctatgtta
     4321 acaggtgaat ctatccctgt tgagaagaat gttgatgata ctgtaattgg ttcaacgatg
     4381 aacaaaaacg gtactattac tatgacagca acaaaagttg gcggggacac tgcgttggca
     4441 aatattatta aagttgtcga agaagctcaa agttctaaag cgccgattca acgattggca
     4501 gatattattt ctggttattt cgttcctatc gttgttggta tcgcactatt aatatttatc
     4561 gtgtggatta ctttagttac accaggtaca tttgaacctg cacttgttgc gagtatttcc
     4621 gttcttgtca ttgcttgtcc atgcgcatta ggacttgcta caccaacttc tattatggta
     4681 ggtactggtc gcgctgctga aaatggcatt ttatttaaag gtggcgagtt tgttgaacgc
     4741 acacatcaaa ttgataccat cgttttagat aagacgggta ccattacaaa tggtcgtcca
     4801 gtcgtgacag attatcatgg tgacaatcaa acgctacaac tgcttgctac tgctgaaaaa
     4861 gattctgaac acccattggc agaagccatt gtcaattatg caaaagaaaa gcaattaaca
     4921 ttaactgaga caacaacatt taaagcagta cctggccatg gtattgaagc aacgattgat
     4981 catcaccata tattggttgg taaccgtaaa ttaatggctg acaatgatat tagcttgcct
     5041 aagcatattt ctgatgattt aacacattat gaacgagatg gtaaaactgc tatgctcatc
     5101 gctgttaatt attcattaac tggtatcatc gcagtggcag atactgtcaa agatcatgcc
     5161 aaagatgcta taaaacaatt gcatgatatg ggcattgaag ttgccatgtt aactggcgat
     5221 aataaaaaca ctgctcaagc cattgcaaaa caagtaggca tagatactgt tattgcagat
     5281 attttaccag aagaaaaagc tgcacaaatt gcgaaactac agcaacaagg taagaaggtt
     5341 gcgatggttg gtgacggtgt aaatgatgca cctgcattag ttaaagctga tatcggtatc
     5401 gccattggta caggtacaga agttgccatt gaagcagctg atattactat tcttggtggc
     5461 gacttgatgc ttattcctaa agccatttat gcaagtaaag caaccattcg taatattcgt
     5521 caaaatctat tttgggcatt cggctataat attgccggta tccctatagc tgcattgggc
     5581 ttacttgcgc catgggttgc tggtgctgca atggcactaa gttcagtaag tgttgtcaca
     5641 aacgcactta gattgaaaaa gatgcgatta gaaccacgcc gtaaagatgc ctagattcct
     5701 taataatgaa ggattcgttg gtgattctga gataggctag tgattggctc tataatgtcg
     5761 cggtttacag ttgggtcttc gctcctactg catatatagt tacacttttc gcttagcgaa
     5821 ttagtgtatc ttacctaata gcttcgccta ttaggttcca tcattattat aaataataag
     5881 tacactacgg tttacagttg gatcttcgct cctactgcat atatagttac acttttcgct
     5941 tggcgaatta gtgtatctta cctaatagct ccgcctatta ggttccatca ttattataaa
     6001 taataagtac actatggttt acagttggat cttcgctcca actgcataag agcctgagac
     6061 ataaatcaat gttctatgct ctacaaagtt ataatggcag tagttgactg aacgaaaatg
     6121 cgcttgtaac aagctttttt caattctagt caactttgcc ggggtgggac gacgaaataa
     6181 attttacgaa aatatcattt ctgtcccact ccctaaaagg aggtgaatgc tatgtcacaa
     6241 gaaattttaa atgttgaagg tatgagctgt ggtcactgca aaagtgctgt tgaatctgca
     6301 ttaaataata ttgacggtgt cacttcagct gacgttaacc ttgaaaatgg tcaagtaagt
     6361 gttcaatatg atgacagtaa agttgctgta tctcaaatga aagacgcaat tgaagatcaa
     6421 ggttacgatg tcgtttaatt aggcaatatt caacgtcatc aacaccaaat taaaaaaatc
     6481 gaactgatga gaatcccaac aatccaaatt atctcatcag ttcgattttt aatttactcg
     6541 taacctagta tctccagtct gcaatacatc taatgttgca tctaatgcat cgacaattag
     6601 atttttaact gcagcttcag tataaaacgc aatatgtggt gttaatatga catcttccct
     6661 gtcaatcaac gattctaaca atggatcgtt cggtgttttg cccctttgat cacttgggaa
     6721 aagtttgcgt tcaaattcat acgtatcaag tgctgcacct ttaatcacac cattgtctaa
     6781 tgcgtctaat aacgccttag tatctactaa agaacctctc gcacaattga caaatactgc
     6841 gcccttttta aaatgtttaa ataattcagc attaaataga taatgattat atttcgttgc
     6901 aggtacatgt aatgtcacga tatcagcacc ttcaaccgct tcctcaatcg tatctttgta
     6961 atcgacatac gttgcaattt tagcattagg aaacgggtcg tatgcgacca catcactttg
     7021 ataaccattg gcaaatatat cggctactac acggccaatt cgacctgtac caataacagc
     7081 tacttttaaa tctttaatgg atttcgataa aatagtaggt tcccatctaa aatcatgctc
     7141 ccgcactttc gtttgaattt gattaaaatg acgaaccaca ttaatagcct ggttcacagc
     7201 aaactccgca attgaattcg gagagtatga cggcacattt gacacaatca agttatactt
     7261 gtttgctaac tccaaatcat atgtatcaaa tccagcacta cgttgtgcga tttgtttaat
     7321 acctagttca tttaatcgtt tataaacatg ctctgataat ggtatttgtt gtgatagcga
     7381 taagccatca taaccagcga caccttcaac attgtcatca gttaatgctt ctttagtaat
     7441 atctacctca acatgatgtt tctctgccca cgccttgata taaggcatat cttcatcacg
     7501 tacactcatg attttaattt ttgtcatttt aacatcaccc ttaactttat tattcatata
     7561 aatatgctag ttctgttaat cttattgcag cttcgtctaa tttctggtca tctaacgcca
     7621 atgaaattct cacataacga ttaccattct ctccaaatgg tttccctgga gcaacaagta
     7681 ttgacttctc ttgcactaaa aattgctcaa attgctcgct gtcataacca ggcggtgttt
     7741 ccaaccatac atatatgcca cctttagcat gaacaaatgg caaatcagct tttgcaagca
     7801 tggcttcgaa tcggtcacga cgtgttttaa atacattgct ttgttcttct aaaaaatcat
     7861 cataatgatt caaagcatat attgcggcat cttgtaatgc accaaacatc ccagcatttg
     7921 tgtgcgtttg gtactttttc aaagcttgaa tcatatcttt attaccaact gcaaaaccga
     7981 ctctaaaacc tgacatgtta taacctttag acaaggaata aatttcaatc gcaacatctt
     8041 tcccattttc cgaagcaagt atactaggat ttttagcgtc gaaaccgaaa gcaccataag
     8101 caaaatcatg cacgatttta gtgtctgtac ctttaaattt agctatcgct tcatcaaaaa
     8161 cttctttcgt agctgtcgat ccagttggat tatttggata cgttaaataa atgagttttg
     8221 ttttatctat tatttgtgaa tcaactgtgg accaatctgg caaataatgt ggcggttcta
     8281 aattaagcgg aactggcttg ccatcagcta aaagtacacc tgctaaatag tccgtgtagc
     8341 ctggatcagg tagtaataca tagtctcctg gattgataac acatgttggt actgccacta
     8401 atccattttt tgtaccatat aaaatgcata cttcatcttc tttatctaac gtcacattat
     8461 attgtctttg ataaaaatct acaatagctt gcttgaacgc ttctttacca tgaaaagcac
     8521 catatttttg attttcagga atagttagtg ctttttgaaa atgatcaata ataccttgtg
     8581 gcgtgggccc atcagggatc ccaactgcca tattaattaa tggcaatggt ccatgttcga
     8641 ttttacgtcc catcgttttc ccgaaataac tatcagggat atttgctaat ttgttagaga
     8701 tcatcaaatt cctcctctat cattaaacat agcctgggcg actatcataa tcctaacaac
     8761 ttgtatcact ctcatttaga tggttacaat gacatcgcca ttcaccgtta tgttcaacag
     8821 aacttatgac acacgttgta ttgaatgaat ttattttcat tttaggtagg tacattatta
     8881 ttgtcaatat taggaatttt cagattaata tgcactcaat cgttatgatt taactgtcat
     8941 gcatatccgc atgcgcaacc agttagatat gcttatataa agtataacgc ccctcaaggt
     9001 acgtattcaa acgtgaacct taacaggcgc ctattcattg ttaaataaaa cttctttaga
     9061 acatacttat ttcactatgc cttttacttt ccccttatac ttttctcaca tctttctctt
     9121 agactactcc cttatacgcc ccgctcaata tctttaatca tttcgtctac agttattttc
     9181 gcacttgtta agacaatagg aacgcctgca cctgggtgcg tacttgcacc tgcaaaatat
     9241 aaatctttat aatctcgcga tacattttgt ggacgataat aattactttg cgctaaagtt
     9301 ggcattaaac cgaatgccga accaaatttc gcatgatacg tttgctcaaa atcatttggc
     9361 gtaaagattg tttctgaaac aatatgcgat tttatatctt caaatacttc aattgttcct
     9421 aatttacgat aaataatttc ctttatttgt tgcgtcaaag cttcatctga ccaatcgatt
     9481 ccgctacctg ttttaagttc cggcgtcggc attagcacat aaataccagt tttgccttct
     9541 ggcgcaagtg atttatcagc gaccgctggt acatacacat aaatagaagg atcatatgat
     9601 aaacgtccct caaatatttc ttcaatattg cctctaaagt catctgaaaa aataacatta
     9661 tgaagtctca cttgatctgt cacatcaata tctataccga tatacattaa aaatgctgaa
     9721 caagagtaat ctaagtctgc aattttatgt ggtggatact ttttaatagg tgcaaaatct
     9781 ggcattaatg attccgcaac actagggaaa tcagccgtac ataaaatttt atcaaatttt
     9841 cttatgtcac cattcacttt tatcgcatcg gcccgtttga atttaggatc aataataatt
     9901 tgctcaattt cagcatttag ttcaatatta acgcctaagt ctttatttaa ttgcgctagc
     9961 ccttgagcca taccatacat accgccttta ataaaatgca caccaaacat catttcaatc
    10021 ataggaataa ttgaatatag tgacgggcct cgttttggat caattcctat gtataacgtt
    10081 tgaaacgcta aaagcttttg tatcttttcg ttatcaatat aatgttcaat tagctgatct
    10141 gcatgattta acgtttttaa cttagcacct tgcacaagtg acgtcatatt ataaaagtca
    10201 ctcggtttgc gatacgttct ttctaagaaa tagcgacgtg caatttcata ttttttataa
    10261 acatccgtta aaaaggacat aaaaccatgc gttgaaccag gttctatact ttctagcatt
    10321 tgctgtaatt cagctaaatc tgtaggcacc gttatacgat catcgtggtc aaaatacaca
    10381 tcgtaaatat aacgtaattg tctcaattca atataatctt cataattttt accacacgct
    10441 gtaaaaacat ctttataaac atctggcatc atgacaattg tgggacccat atcaaatgta
    10501 aagccgtctt tctttaattg attcatacgc ccgcctacat tattattttt ttcaaatatc
    10561 gtcacttcat gaccttgaga agcaatacgg gctgccgctg ctaatcctgt gacacctgca
    10621 ccaattactg caatcttcat tattcaacca cctatattct atgatattta ctatttattt
    10681 catgaaacaa ctttgccttt ttccgcttat ccacaaaaac acgttcatgt aatgtatagt
    10741 tagcctgtct cacttcgtcc agtatttcaa tatatatacg tgctgctaat tctatgattg
    10801 gttgtgcttc aatactaaat actttgattt gatccataac atcttgaaaa tctttttctg
    10861 cgatagctgc ataatattcc cataagtcaa tataatgatt attaacacca ttttggtaca
    10921 cttcagcaat atcaacttca tattgcttta atcgttgctt actaaaatat acccgttcat
    10981 tgtcaaaatc ttcaccgaca tctcttaata tattaatcaa ttgcaacgat tcaccaagtc
    11041 ttcttgcgac atcgtatgtc tgatgtgttt catgatcact taaaatcggc gtcaatactt
    11101 cacctactgt accagcaaca ccataacaat atccgaataa ttcagcgtcc gtttcaaaca
    11161 ttgtaaaatg ttgatcttta tatacagtat caatgagatt ataaaaagat tgaaaggcga
    11221 tatttttatg ttgtgcaaca tgctgaagcg ccatcatgat tctacgatca ctttgaaagt
    11281 gatgatgttc atatgggtat ttttcaatag attgtatatc ttcttttatt tgatttaaaa
    11341 attgaatatc gccataaaca tctatactgt catcaatttt acgacacaca gcataaattg
    11401 cccaaaccgc ttttctttga tcttctggta acaagtcaaa agcgtaagaa aagctttttg
    11461 aatgtttctt catgatttta tgacaatatt taaaattcat atccatcatt gtcatactag
    11521 tcctcctata ttgaaatgcc attaccttga tttattgttc tttagatata gaatattgac
    11581 gacctttcca ttcaactaca ccataacgat gcgtttgttt ccaagattgg atgaaaattt
    11641 tagtaaaaaa cataaataac aatggatgac ataccattaa caaattagaa aattggccga
    11701 cccttcgatg cagataaata aattgtgtag tatagctcaa gtaaagtgct accatttttc
    11761 ttacagacat ttggcgatat tttaaactaa gacatagccc taaaatactc gctatagaac
    11821 cgaacaacca caacacaatt gctgtcatga tcttaggctt tgtgccacct gccccagttg
    11881 acaaatgctt tgtccatcct tcttgtaatg actgaaatcc ttcttgatac atgcgaaatg
    11941 caacaaatgg aaatccttca taaactgtta cgggcaatga ttgtgaagta tatgcacttc
    12001 ctaaagcaaa tccttcaata atatgacggt tcgcactttt atgacctcca gttgcataat
    12061 aatcttcttt atttgttaat gtcaccggtc caaatgcatg ctggttagtc cgaccgtcgt
    12121 ctaaggtaga aaatacattc ataccaacga ctgtcattaa attaaatatc gctgaaaacc
    12181 cttcgtagaa acgctttgtt atatgataag gctgtacgct taacaatcct ttttcacctt
    12241 gtaattgata ctgattaatc aacgtttcaa cagcatcttt ccttaagaaa gttacatcag
    12301 catctacaaa ggcaatacga ttcgtacatg catgcgtcac accttgataa caagcatgtg
    12361 atttcccata ccatttgccg tcagtatcat caacaacatc tactacagtc gcaccatatg
    12421 aacgtgctac acgtgctgtt tcatctgtcg atccgtcatt cataacaatg acatctactg
    12481 gaacttgctg ttgtattatc gaatgtagta aatgacctat tcttttttct tcatttctag
    12541 ccggaataat aattgttaat gctttatgat tgaagttcag cgttttcgtc tttagctgat
    12601 gtctacgatt aaatatcaat gcaccacacg ccatagacat ggtcactatt actgttaata
    12661 ttcgtgataa ccatttcata gatatcactt cctattcttc gtttctcgcg cgtttatttt
    12721 gtctgcgact tgttgcccac ttaatgtaac cattggcatg ccaccaccag gatttactga
    12781 tccacctaca aagtacaagt tttcaaaata ctgactttct ttaggaaatt taaatccttt
    12841 gtttttcttt ttatctgcta caacaccata tattgcacca cgattagaac gataattttt
    12901 ttcaatatcc tccggtgtcc aaacatcttc ataaataatg tgttttctta aatcagtaag
    12961 tcccattttt tctaatttat ccaaaatttt atccctaaac ttcgcataat cttcagtggt
    13021 aaaaggctga tcttgaatat atggaatatg tggtaagact ttgatatttt cataacctac
    13081 tggcgcttgt gtgtgatcag ttttattcgt atttactaga taaatggtcg gatcatctgg
    13141 caataccttt tcatgaaaaa cttgttgata attgagataa gcattttccg taaaaaagaa
    13201 attatgatgt gctaattgcg ggtattggca agcaacacct aaatgcatca catatcctga
    13261 gcttgccggc tcaaattccc tctctaattt gtttaatcgt tgagtatcaa ggtgaattaa
    13321 atatttataa gtaggtatga cttccatatt tgaaataata taatctgcct ttacaaactc
    13381 acctgtatct aatctgacac ccgtcacacg tctttgatat gttttaatat tgtccacacg
    13441 tgcacctgta tgaattgtga caccttcttc acgcgctagc ttttccaagg cattggctaa
    13501 atgatggatt ccaccttcta cataccaaag gccttgctct tgttgcatat ggaataacat
    13561 agataataca gctggcgcat cgtatgatga agaacctaca tatttgataa aatagcctaa
    13621 catttgtcgc aagtatggat tcgagatacg cttgtctatg gcctgttgca tagtatgtac
    13681 ataatcataa ttaataagag catttaatgg cccatgaaat ttaataattt gagatagtgt
    13741 atctaaacca tagttaaaat accctttttc agtaatacga tcgattcgtc ttgtataatt
    13801 caaataattt tgcagttcct ctatatcctg tttcgacaat atcgcattat gctgacctgt
    13861 ttctttaata ccttcataca aatcgatagt cgtgccatct ggaaaaaagc tacgccattg
    13921 atgtggcaaa cgcttgattg taacgtagtc tgacatttgc ttcttgctat attcgaataa
    13981 tttttcaaaa atataaggca tcgttaaaat agatggacct aaatcaaagc caaagccatc
    14041 tgattcatga cgattcactt tgcctcctat atgagtattt tgttcatata atgagaccga
    14101 atagccactt tgtgccattc gaattgctgc agaaatccca cctaagccac caccaataac
    14161 gatgatatgt ttagtcatga cgttcacctc ttcgttttaa tatgcgtagt aactgcgtta
    14221 atctcggtcg attatagcgt tgcacaataa tgattggaac attagctatc attgcataga
    14281 aaatatttat atactttact aaacgagagc ctttattgaa tatgatgact ggaagtatcg
    14341 atatccaatg aatcaactct gccctctttg tctctataat cattttttca atttcatcag
    14401 tattgattgt cattaaatga cgctgatcat atatattttg attaagctga tgaccatcta
    14461 aaatcttatg tttccatttt cttacgtaaa accatttgtt ccaaaatttt ccatgcttct
    14521 caaaattaaa tgatttaaat attatgtact tctgacgaaa atacttatca ggaattcttg
    14581 tacctaaatt tgctatattt agttgaacaa ttaaccaata catactacaa aaaaatgctg
    14641 ttttgatata ttttttcatg attttcatct aaattgaatc actctcaatc ata
//
LOCUS       DAPDIM010000064        14509 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000064 DAPDIM010000000
VERSION     DAPDIM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 14509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14509
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.064"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(1011..1940)
                     /locus_tag="RFE25_002208"
     CDS             complement(1011..1940)
                     /locus_tag="RFE25_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDU2817244.1"
                     /translation="MKKLVPLLLALLLLVAACGTGGKQSSDKSNGKLKVVTTNSILYD
                     MAKNVGGDNVDIHSIVPVGQDPHEYEVKPKDIKKLTDADVILYNGLNLETGNGWFEKA
                     LEQAGKSLKDKKVIAVSKDVKPIYLNGEEGNKDKQDPHAWLSLDNGIKYVKTIQQTFI
                     DNDKKHKADYEKQGNKYIAQLEKLNNDSKDKFNDIPKEQRAMITSEGAFKYFSKQYGI
                     TPGYIWEINTEKQGTPEQMRQAIEFVKKHKLKHLLVETSVDKKAMESLSEETKKDIFG
                     EVYTDSIGKEGTKGDSYYKMMKSNIETVHGSMK"
     gene            complement(1937..2773)
                     /locus_tag="RFE25_002209"
     CDS             complement(1937..2773)
                     /locus_tag="RFE25_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDU2817245.1"
                     /translation="MLEFVEHLFTYQFLNRALITSIIVGIVCGTVGSLIVLRGLSLMG
                     DAMSHAVLPGVALSFLFGIPMFVGALITGMIASIFIGYITSSSKTKPDAAIGISFTAF
                     LASGIIIISLINTTTDLYHILFGNLLAITNSAFLTTIVIGSIVLILIIIFYRPLMIST
                     FDPTFSRMSGLNTTLLHYFVMLLLSLVTVASIQTVGIILVVALLITPASTAFLISKKL
                     YSMMIIASLISVISSIVGLYYSYIYNIPSGATIVLCTFVIYIITLFFTKFTNRKKRGS
                     LT"
     gene            complement(2767..3510)
                     /locus_tag="RFE25_002210"
     CDS             complement(2767..3510)
                     /locus_tag="RFE25_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDU2817246.1"
                     /translation="MLETKDLNLFLGNKHVLKNISLSIPVRGEIIGIMGPNGAGKSSL
                     IKSLIGEFNATGTKLLYNKPIQQQLQHITYIPQKAHIDLDFPISVEQVILSGCYKEIG
                     WFRRPNKSARDKLKQLLSDLELESLRHRQISELSGGQLQRVLVARALMSESEVYFLDE
                     PFVGIDFSSEKLIMTKIENLKQQGKLILIIHHDLSKAKQYFDRIILLNQTLRYFGDSE
                     EAMSVTRLNETFMSSTDCSDPSQRSNITC"
     gene            3632..4276
                     /locus_tag="RFE25_002211"
     CDS             3632..4276
                     /locus_tag="RFE25_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDU2817247.1"
                     /translation="MLTEEKEDYLKAILTNNGDKNFVTNKILSQFLNIKPPSVSEMVG
                     RLEKAGYVETKPYKGVRLTEDGLTHTLDIIKRHRLLELFLIEILKYNWEEVHQEAEIL
                     EHRISDLFVERLDSLLNFPETCPHGGVIPRNNEYKEKYITTILNYEPGDIVTIKRVRD
                     KTDLLIYLSSKDISIGNEVEIVSKDEMNKVIIIKRNDNVIIVSYENAMNMFAEK"
     gene            complement(4356..5108)
                     /locus_tag="RFE25_002212"
     CDS             complement(4356..5108)
                     /locus_tag="RFE25_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HDU2817248.1"
                     /translation="MNYLSNFFNTTIQLNIYIIVIVAACYIAIHQYRHKPVLNYLDVI
                     LNYIPVLTHEFGHVLFNKLAGGRAKDLVIVTSPRERQQTLQQGFAITQSRHLAGQWLT
                     TIGGYLMPPIMLLIGLASSHYQIPSFFIFTYLLIFIYFLILTSRKGSPIVVITLISIM
                     LYFILKDENIVEIQLLVTMSYQYILGVLLGEVLQSSWTIAKLTFQRPSPQWDGSALKE
                     LSHVPIFIYSTIWIIFNLYAVNILLKYTHLIN"
     gene            5344..6108
                     /locus_tag="RFE25_002213"
     CDS             5344..6108
                     /locus_tag="RFE25_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HDU2817249.1"
                     /translation="MTVEERSNTAKVDILGVDFDNTTMLQMVENIKTFFANQSTNNLF
                     IVTANPEIVNYATTHQAYLELINQASYIVADGTGVVKASHRLKQPLAHRIPGIELMDE
                     CLKIAHVNHQKVFLLGATNEVVEAAQYALQQRYPNISFAHHHGYIDLEDETVVKRIKL
                     FKPDYIFVGMGFPKQEEWIMTHENQFESTVMMGVGGSLEVFAGAKKRAPYIFRKLNIE
                     WIYRALIDWKRIGRLKSIPIFMYKIAKAKRKIKKAK"
     gene            complement(6169..6963)
                     /gene="tagH"
                     /locus_tag="RFE25_002214"
     CDS             complement(6169..6963)
                     /gene="tagH"
                     /locus_tag="RFE25_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acids export ABC transporter
                     ATP-binding subunit TagH"
                     /protein_id="HDU2817250.1"
                     /translation="MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDIS
                     LKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTG
                     IENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITV
                     NPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEG
                     GKLKDYGELDDVLPKYEAFLNDFKKKSKAEQKEFRNKLDEARFVIK"
     gene            7310..8122
                     /gene="tagG"
                     /locus_tag="RFE25_002215"
     CDS             7310..8122
                     /gene="tagG"
                     /locus_tag="RFE25_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acids export ABC transporter permease
                     subunit TagG"
                     /protein_id="HDU2817251.1"
                     /translation="MSAIGTVFKEHVKNFYLIQRLAQFQVKIINHSNYLGVAWELINP
                     VMQIMVYWMVFGLGIRSNAPIHGVPFVYWLLVGISMWFFINQGILEGTKAITQKFNQV
                     SKMNFPLSIIPTYIVTSRFYGHLGLLLLVIIACMFTGIYPSIHIIQLLIYVPFCFFLT
                     ASVTLLTSTLGVLVRDTQMLMQAILRILFYFSPILWLPKNHGISGLIHEMMKYNPVYF
                     IAESYRAAILYHEWYFMDHWKLMLYNFGIVAIFFAIGAYLHMKYRDQFADFL"
     gene            8221..9324
                     /locus_tag="RFE25_002216"
     CDS             8221..9324
                     /locus_tag="RFE25_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDU2817252.1"
                     /translation="MNVLIKKFYHLVVRILSKMITPQVIDKPHIVFMMTFPEDIKPII
                     KALNNSSYQKTVLTTPKQAPYLSELSDDVDVIEMTNRTLVKQIKPLKSAQMIIIDNYY
                     LLLGGYNKTSNQHIVQTWHASGALKNFGLTDHQVDVSDKAMVQQYRKVYQATDFYLVG
                     CEQMSQCFKQSLGATEEQMLYFGLPRINKYYTADRATVKAELKDKYGITNKLVLYVPT
                     YREDKADNRAIDKAYFEKCLPGYTLINKLHPSIEDSDIDDVSSIDTSTLMLMSDIIIS
                     DYSSLPIEASLLDIPTIFYVYDEGTYDKVRGLNQFYKAIPDSYKVYTEEDLIMTIQEK
                     EHLLSPLFKDWHKYNTDKSLHQLTEYIDKMVTK"
     gene            9321..10382
                     /locus_tag="RFE25_002217"
     CDS             9321..10382
                     /locus_tag="RFE25_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDU2817253.1"
                     /translation="MRLTIIIPTCNNEATIRQLLISIESKEHYRILCIDGGSTDQTIP
                     MIERLQRELKHISLIQLQNASIATCINKGLMDIKMTDPHDSDAFMVINPTSIVLPGKL
                     DRLTAAFKNNDNIDMVIGQRAYNYHGEWKLKSADEFIKDNRIVTLTEQPDLLSMMSFD
                     GKLFSAKFAELQCDETLANTYNHAILVKAMQKATDIHLVSQMIVGDNDIDTHATSNDE
                     DFNRYIIEIMKIRQRVMEMLLLPEQRLLYSDMVDRILFNNSLKYYMNEHPAVTHTTIQ
                     LVKDYIMSMQHSDYVSQNMFDIINTVEFIGENWDREIYELWRQTLIQVGINRPTYKKF
                     LIQLKGRKFAHRTKSMLKR"
     gene            10445..10843
                     /gene="tagD"
                     /locus_tag="RFE25_002218"
     CDS             10445..10843
                     /gene="tagD"
                     /locus_tag="RFE25_002218"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HDU2817254.1"
                     /translation="MKRVITYGTYDLLHYGHIELLRRAREMGDYLIVALSTDEFNQIK
                     HKKSYYDYEQRKMMLESIRYVDLVIPEKGWGQKEDDVEKFDVDVFVMGHDWEGEFDFL
                     KDKCEVIYLKRTEGISTTKIKQELYGKDAK"
     gene            complement(10960..12255)
                     /gene="pbp4"
                     /locus_tag="RFE25_002219"
     CDS             complement(10960..12255)
                     /gene="pbp4"
                     /locus_tag="RFE25_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP4"
                     /protein_id="HDU2817255.1"
                     /translation="MKNLISIIIILCLTLSIMTPYAQATNSDVTPVQAANQYGYAGLS
                     AAYEPTSAVNVSQTGQLLYQYNIDTKWNPASMTKLMTMYLTLEAVNKGQLSLDDTVTM
                     TNKEYIMSTLPELSNTKLYPGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVD
                     LMNNKAKAIGMKNTHFVNPTGAENSRLRSFAPTKYKDQERTVTTARDYAILDLHVIKE
                     TPKILDFTKQLAPTTHAVTYYTFNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKR
                     GKFRINQVIMGAGDYKNLGGEKQRNMMGNALMERSFDQYKYVKILSKGEQRINGKKYY
                     VENDLYDVLPSDFSKKDYKLVVEDGKVHADYPREFINKDYGPPTVEVHQPIIQKANTV
                     AKSMWEEHPLFTIIGGACLVAGLALIVHMIINRLFRKRK"
     gene            12676..14403
                     /locus_tag="RFE25_002220"
     CDS             12676..14403
                     /locus_tag="RFE25_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817256.1"
                     /translation="MKRENPLFFLFKKLSWPVGLIVAAITISSLGSLSGLLVPLFTGR
                     IVDKFSVSHINWNLIALFGGIFVINALLSGLGLYLLSKIGEKIIYAIRSVLWEHIIQL
                     KMPFFDKNESGQLMSRLTDDTKVINEFISQKLPNLLPSIVTLVGSLIMLFILDWKMTL
                     LTFITIPIFVLIMIPLGRIMQKISTSTQSEIANFSGLLGRVLTEMRLVKISNTERLEL
                     DNAHKNLNEIYKLGLKQAKIAAVVQPISGIVMLLTIAIILGFGALEIATGAITAGTLI
                     AMIFYVIQLSMPLINLSTLVTDYKKAVGASSRIYEIMQEPIEPTEALEDSENVLIDDG
                     VLSFEHVDFKYDVKKILDDVSFQIPQGQVSAFVGPSGSGKSTIFNLIERMYEIESGDI
                     KYGLESVYDIPLSKWRRKIGYVMQSNSMMSGTIRDNILYGINRHVSDEELINYAKLAN
                     CHDFIMQFDEGYDTLVGERGLKLSGGQRQRIDIARSFVKNPDILLLDEATANLDSESE
                     LKIQEALETLMEGRTTIVIAHRLSTIKKAGQIIFLDKGQVTGKGTHSELMASHAKYKN
                     FVVSQKLTD"
BASE COUNT         5002 a         2158 c         2469 g         4880 t
ORIGIN      
        1 atgaagaacc tgaaaaactg aagggctttt catcaatccc ttttatttta ggggaattga
       61 atagatagtt ttaaactata cgaattatta atatttgaga tttaattgaa ataagtttta
      121 aaaattggag gagatagatt aatcgaagtc atttaaagat gaagataagt gcattcacaa
      181 aaaatagcca cactcatatg acatcggatg agtgtggctt aaggatctat ggggggagga
      241 aaccatagat gtttactttg ataggccaga ttaaatatca aagtatgcga ttatttatag
      301 cttgatgcaa aagtggtatg cctattaaaa gttactgcac atagctttta atattccgtt
      361 caaaggaaag gggcatacaa ttgaacaatc tgtaatagta cttttaacca gctatgctaa
      421 aagtctagta gggagaacag ttgtccaatc acataagaac ctctaacttc gttagtacga
      481 ttaagaaaag ctttttagtt agtatgtaat acaatttatt gacgcgcgtg aatctctttt
      541 ataagagtgt gtagggaatg gcgttgtata aattgtatta gaagaacttc taacgcatct
      601 ctgtggttaa aagagatgaa gggaacgaca gtttaattaa aactgcataa gaacttctag
      661 cttttctctt tcgttcaaag agaagcagct gttcgcagtt taatcaaaac cacataaagc
      721 ttttaacttt actctttgat ttaaagagtg acaaatgttt acagtttaat taaaactgca
      781 taagaacttc tagcttttct ctttcgttca aagagaagtt ctaataccac catatcgtgc
      841 gatcgggaac ggtatatata ttaataggag ggtaatatat atttaacgca cgatatggga
      901 ctattagcct tcgactttgt tatgttgatg tgtagcctaa aatattggag ataccaatat
      961 tttaggttgc atcaacatca attcatctta cttcattaaa acacagcgtg ttatttcatg
     1021 cttccgtgta cagtttcaat atttgatttc atcattttgt agtaagagtc acctttagtg
     1081 ccttctttac cgattgaatc tgtgtacact tcaccaaaga tatctttctt cgtttcttca
     1141 gataaacttt ccattgcttt cttatcaaca cttgtttcta ctaataagtg ttttaatttg
     1201 tgctttttaa caaactcaat agcttgtctc atttgttcag gtgtaccttg tttttcagtg
     1261 ttaatttccc aaatataacc tggtgtaata ccgtattgtt ttgagaagta cttgaaggca
     1321 ccttcacttg taatcatggc acgttgttct tttggaatgt cattaaattt gtctttactg
     1381 tcattattta atttttccaa ttgagcaatg tatttgttac cttgcttttc ataatctgct
     1441 ttatgttttt tgtcgttatc gataaatgtt tgttgaattg tttttacgta tttaatacca
     1501 ttatctaaac ttaaccatgc gtgtggatct tgtttatctt tgttgccttc ttcaccgttt
     1561 aaatagatag gtttaacatc ttttgatact gcgataactt ttttatcttt taatgattta
     1621 ccagcctgtt ctaaggcttt ttcaaaccaa ccgttaccag tctctaaatt taatccgttg
     1681 tataaaataa cgtcagcgtc agttaacttt ttaatatctt taggtttaac ttcatattca
     1741 tgaggatctt gaccaacagg tacaatacta tgaatatcga cgttgtctcc accaacattt
     1801 ttagccatat catataaaat tgaattcgtc gttactactt ttaatttgcc atttgactta
     1861 tcactgcttt gtttaccacc agtaccacat gcagcaacta gaagtaataa ggctaataat
     1921 aaaggtacta attttttcat gttaaacttc ctcgtttctt tctattcgta aattttgtga
     1981 aaaataatgt gatgatataa attacaaacg tacaaagtac gattgtcgca ccactaggaa
     2041 tgttgtaaat atagctgtaa taaagtccga caattgaact tatgacactt attaaacttg
     2101 ctataatcat cattgagtat agttttttac taattaaaaa tgctgtagat gcaggtgtaa
     2161 ttaataatgc aactacaaga ataataccta ccgtttgaat acttgctact gttactaatg
     2221 agagtaacaa catcacaaag taatgtaata acgtcgtatt tagaccactc attctactaa
     2281 acgttggatc gaatgtagaa atcattaatg gacgatagaa aataatgatt agaataagga
     2341 cgattgaacc aatcacaata gttgttaaaa atgcactatt tgtgattgcc agtaaattac
     2401 caaacagaat atggtacaaa tctgtcgtag tgtttattaa gctaataata ataatccccg
     2461 aagctaagaa agcggtaaaa ctaattccaa tagcggcgtc aggtttcgtt ttactactag
     2521 atgtgatata accgataaaa atacttgcga tcataccagt tataagtgcg cctacaaaca
     2581 ttggaatacc aaataagaat gatagggcaa caccaggtaa tactgcgtga ctcattgcat
     2641 ctcccattaa tgaaagacca cgtaatacaa ttaaactacc aactgtacca caaactatcc
     2701 ctacaataat tgaagttatc aatgctcgat tcaagaattg atatgtaaat aaatgttcga
     2761 caaactctaa catgttatat tgctcctttg actagggtca ctacagtcag tgctactcat
     2821 aaatgtttcg tttaagcgag tgacactcat agcctcttca ctatcaccaa agtatcgtaa
     2881 tgtttgattt aatagaataa tgcgatcaaa gtattgcttt gcttttgata gatcatggtg
     2941 gatgataaga ataagttttc cttgttgttt taagttctcg atttttgtca tgattaattt
     3001 ttcgctacta aaatcaattc cgacaaacgg ctcatctaga aaataaactt cactttcgga
     3061 catcaatgct cttgctacta gcacacgttg taattgtcca ccacttaatt ctgaaatttg
     3121 tcgatgacgt aaagattcta attctaaatc gcttaataac tgtttgagtt tatcccttgc
     3181 tgatttatta ggtcgtctaa accatccaat ttctttgtag caacctgata aaatcacttg
     3241 ttccacactt ataggaaaat ctaaatcaat atgtgctttt tgtggaatat atgtaatatg
     3301 ttgcagttgt tgttgtatag gtttgttata taacaattta gtaccggtag cattaaattc
     3361 accaattaaa gacttgataa gggaagattt accagcacca ttcgggccca tgataccaat
     3421 tatttcgccg cgtactggta tcgataagga aatgttttta agtacatgct tattacctaa
     3481 aaacagattt aaatcttttg tttctaacaa acgtttatac ctcctaatta aaagtttagg
     3541 ctaacctaat taattgtata ataaactgag aatatttatc atgtcaagta aattcgtgat
     3601 ataatataga caatgtatgt gaggtgaaag tatgttaact gaagaaaaag aggactattt
     3661 aaaggcaatc cttacgaata atggcgataa aaactttgtg acaaataaaa tcttatctca
     3721 atttttaaat attaagcctc catctgtaag tgaaatggta ggacgtcttg aaaaagcagg
     3781 ctatgttgaa acaaaaccat acaaaggtgt tagattaaca gaggatggtt taacgcatac
     3841 gcttgatatc attaagagac atcgactatt agaattattt ttaatagaaa tattgaaata
     3901 taattgggaa gaagtacatc aagaagcaga aattttagaa catcgaattt cagatttatt
     3961 tgttgaaagg ctggatagcc tgttaaattt cccagaaact tgcccgcacg gcggtgtgat
     4021 tcctagaaat aatgaatata aagagaaata tataacaacg attttgaatt atgaacctgg
     4081 tgatatcgtt acaatcaaac gtgtgagaga taagaccgat ttgctaatat atttgtctag
     4141 taaagatatt tctattggta atgaagtgga aattgtatcg aaagatgaaa tgaataaagt
     4201 aattatcatt aaacgtaatg ataatgtaat tattgtcagt tacgaaaatg caatgaacat
     4261 gtttgctgaa aaataaaata aagaagccat aaagatatcc atgattgaac tgataaagac
     4321 atatggataa ttgctttagg cttctttttt attagttaat ttatcaagtg agtatatttg
     4381 agtaaaatat tcactgcata aagattgaag ataatccaga ttgtactata aatgaagata
     4441 ggtacatgac tgagttcttt aagtgcacta ccatcccact gtggactcgg acgctggaaa
     4501 gtcaatttag caatcgtcca actagattgt agaacttcgc ctaataatac acctaaaata
     4561 tattgataac tcattgtgac aagtagttga atttctacta tattttcatc ttttaatata
     4621 aaatacaaca tgatagaaat taaagttata acaacaatgg gtgagccttt tctagatgtt
     4681 aaaattaaaa aataaataaa tatcaataaa taggtaaata taaagaaact aggtatctga
     4741 taatggctcg acgctaaacc tatcaataac ataataggtg gcattaaata accaccaatc
     4801 gttgtaagcc attggcctgc tagatgtcta gattgtgtaa ttgcgaatcc ttgttgtaat
     4861 gtctgttgtc gctctcgtgg acttgttaca atgactaaat cttttgcacg gccaccagcg
     4921 agtttattaa acagtacatg accaaattca tgtgttaaaa cagggatata gtttaaaatg
     4981 acatctaaat agttcaaaac aggcttatgt ctatattgat gaatagcaat ataacaagct
     5041 gcaacaataa cgataatgta tatattaagt tgaattgtcg tattaaaaaa gtttgataaa
     5101 taattcattg ttaacctcat ataagatatt aatttaaagt ttgcttagca cttattataa
     5161 atgatattgg catcaatagc gttagacttt agacttacct tagttaaact aattttaatt
     5221 tttgaaaagg tgaatatgtg ttaaaataaa gcaaaatcat ttcgatataa ataggatgaa
     5281 tataaatact gttaatattg attacactaa cataataatg aaataagata ggagattcct
     5341 gttatgactg ttgaagaaag atccaataca gccaaagttg acattttagg ggtcgatttt
     5401 gataatacaa caatgttgca aatggttgaa aatattaaaa ccttttttgc aaatcaatca
     5461 acgaataatc tttttatagt aacagccaac cctgaaatag tgaattacgc gacgacacat
     5521 caagcgtatt tagagttaat aaatcaagcg agctatattg ttgctgatgg gacaggagta
     5581 gtcaaagctt cgcatcgttt aaagcaacct ctagcgcatc gtatacctgg tattgagttg
     5641 atggatgaat gtttgaaaat tgctcatgta aatcatcaaa aagtattttt gctaggggca
     5701 actaatgaag ttgtagaagc ggcacaatat gcattgcaac aaagatatcc aaacatatcg
     5761 tttgcacatc atcacggtta tattgattta gaagatgaga cagtagtaaa acgaattaaa
     5821 ctgtttaaac ctgattacat atttgtaggt atgggattcc ctaaacaaga agaatggatt
     5881 atgacacatg aaaaccaatt tgaatctaca gtgatgatgg gcgtaggtgg ttctcttgaa
     5941 gtatttgctg gggctaaaaa gagagcgcct tatatattta gaaaattaaa cattgaatgg
     6001 atatatagag cattaataga ttggaaacgt attggtagat tgaagagtat tccaatattt
     6061 atgtataaaa tagccaaagc aaaaagaaaa ataaaaaaag cgaaatagtc atgatgataa
     6121 aaataaaacc gaggaaatcc ttaaatggag attctcggtt ttttcggttt atttaataac
     6181 gaagcgggcc tcatcgagtt tgtttctaaa ttctttttgt tcggctttgg atttcttttt
     6241 aaaatcgtta aggaaagctt catatttagg taatacatca tcaagttcac cgtaatcttt
     6301 taactttccg ccttcaatcc aagcaatctt agtacaaaat tgtctcactt ggcctaagtt
     6361 atgactaacg aaaaagatgg ttttgttttg ctctttaaac tcgtaaattt tatctaaaca
     6421 tttttgtgca aaagtttggt cacctacaga taaagcttcg tcaatgacta agatatctgg
     6481 attaactgtg atattaattg aaaaaccaag ttttgcacgc ataccacttg aatacttttt
     6541 aactggttga taaataaact caccaagttc actaaattca ataatcttag gtgtcatcgc
     6601 tttaatttct tttcgcttaa agcccataca taacatttta aattcgatat tttcaatccc
     6661 tgtaagttgt ccactcaagc cagcactaat tgcgataacg ctgacttcac cattacgatc
     6721 cactttgcca acagtaggcg acaaagaacc gccaatgata ttgctcaacg ttgatttgcc
     6781 ggaaccattg atgccaacaa gccctatgac gtcaccttca tatgctttta aactaatgtc
     6841 atctaaagcg aaaaatgttt tgtttttatg tttgggaatg agcgcatctt tcatacgttc
     6901 tttatttgta cgataaatac gatattcttt tgttacattt ttaatgttta ccgaaacgtt
     6961 catttgtaga ccttccttat tcacatttat ctagattata atatactact caacagttgt
     7021 taaattttaa aacctgttgt aaagtgtata gaagattttg ttattatcag agttggtgtt
     7081 ttgacacaaa atgttaatca tcaatgataa caatgatatt taaaaactaa acttatttca
     7141 acttacatga ttgtatacta taatgtattt gtaataaact aatattttaa agaactagac
     7201 aataattttg atagcatcca tgtatagtga tagtatttac aacaattatt ataatactat
     7261 ttagttaagt agagaaatag ttaaacattt gaaagtgtgg tttaatggaa tgtcagcaat
     7321 aggaacagtt tttaaagaac atgtaaagaa cttttattta attcaaagac tggctcagtt
     7381 tcaagttaaa attatcaatc atagtaacta tttaggtgtg gcttgggaat taattaaccc
     7441 tgttatgcaa attatggttt actggatggt ttttggatta ggaataagaa gtaatgcacc
     7501 aattcatggt gtaccttttg tttattggtt attggttggt atcagtatgt ggttcttcat
     7561 caaccaaggt attttagaag gtactaaagc aattacacaa aagtttaatc aagtatcgaa
     7621 aatgaacttc ccgttatcga taataccgac atatattgtg acaagtagat tttatggaca
     7681 tttaggctta cttttacttg tgataattgc atgtatgttt actggtattt atccatcaat
     7741 acatatcatt caattattga tatatgtacc gttttgtttt ttcttaactg cctcggtgac
     7801 gttattaaca tcaacactcg gtgtgttagt tagagataca caaatgttaa tgcaagcaat
     7861 attaagaata ttattttact tttcaccaat tttgtggcta ccaaagaacc atggtatcag
     7921 tggtttaatt catgaaatga tgaaatataa tccagtttac tttattgctg aatcataccg
     7981 tgcagcaatt ttatatcacg aatggtattt catggatcat tggaaattaa tgttatacaa
     8041 tttcggtatt gttgccattt tctttgcaat tggtgcgtac ttacacatga aatatagaga
     8101 tcaatttgca gacttcttgt aatatattta tatgacgaaa ccccgctaac cattaataaa
     8161 tggaagtggg gttcattttt gtttataatt taagtaaata acatattaag ttggtgtatt
     8221 atgaacgttt taataaagaa attttatcat ttggtagttc gaatactttc taaaatgatt
     8281 acgcctcaag tgattgataa accgcatatc gtatttatga tgacttttcc agaagatatt
     8341 aagcctatca tcaaagcatt aaataattcg tcgtatcaga aaactgtttt aacaacacca
     8401 aaacaagcgc cttatttatc tgaacttagc gacgatgttg atgtgataga aatgactaat
     8461 cgaacattgg taaaacaaat taagcctttg aaaagcgcgc agatgattat tatcgataat
     8521 tattacctat tactaggtgg atataataag acttctaatc aacacattgt tcaaacgtgg
     8581 catgcaagtg gtgcattaaa aaactttgga ttaacagatc atcaagtcga tgtgtctgac
     8641 aaggcaatgg ttcagcagta ccgtaaagtt tatcaagcga cggattttta cttagtgggt
     8701 tgtgaacaaa tgtcacaatg ttttaaacag tctttaggtg caacagaaga gcaaatgctg
     8761 tattttgggc ttccgagaat taataaatat tacacagctg atagagcaac ggttaaggca
     8821 gagttaaagg ataaatatgg aattacaaat aagttggtat tatatgtacc aacatataga
     8881 gaagataaag cagataatag ggctattgat aaagcttatt ttgaaaaatg tttaccagga
     8941 tatacactga ttaataaatt acatccatca attgaagatt cagacattga tgacgtatct
     9001 tcaatcgaca cgtctacatt aatgctaatg tcagatataa ttattagcga ctatagttcg
     9061 ctgccaatag aagctagctt gttagatatt ccaactatat tttatgtgta tgatgaagga
     9121 acatatgata aagtgagagg cctgaatcaa ttttacaaag caataccgga tagctacaaa
     9181 gtgtatactg aagaagattt aataatgacg atacaagaaa aagaacatct attaagtccg
     9241 ttatttaaag attggcataa gtataatact gataaaagtt tacatcagct cacagaatat
     9301 atagataaga tggtgacaaa atgaggctta cgataatcat acctacatgt aataatgagg
     9361 caacaattcg acaattgtta atatctattg agagtaaaga acactataga atcctttgta
     9421 ttgatggtgg ttctactgat caaacaattc ctatgattga acggttacaa agagaactca
     9481 agcatatttc attaatacaa ttacaaaatg cttcgatagc tacgtgtatt aataaaggtt
     9541 tgatggatat caaaatgaca gatccacatg atagtgacgc atttatggtc ataaatccaa
     9601 catcaatcgt attgccaggt aaattagata ggttaactgc agctttcaaa aataatgata
     9661 atattgatat ggtaataggg cagcgagctt acaattacca tggtgaatgg aaattgaaaa
     9721 gtgctgatga gtttattaaa gataatcgaa tcgttacatt aacggaacaa ccagatttgt
     9781 tatcaatgat gtcttttgac ggaaagttat tcagtgctaa atttgctgaa ttacagtgtg
     9841 acgaaacttt agctaacaca tacaatcacg caatacttgt caaggcgatg caaaaagcta
     9901 cggatataca tttagtttca cagatgattg tcggagataa cgatatagat acacatgcta
     9961 caagtaacga tgaagatttt aatagatata tcatagaaat tatgaaaata agacaacgag
    10021 tcatggaaat gttactatta cctgaacaaa ggctattata tagtgatatg gttgatcgta
    10081 ttttattcaa taattcatta aaatattata tgaatgaaca cccagcagta acgcacacga
    10141 caattcaact cgtaaaagac tatattatgt ctatgcagca ttctgattat gtatcgcaaa
    10201 acatgtttga cattataaat acagttgaat ttattggtga gaattgggat agagaaatat
    10261 acgaattgtg gcgacaaaca ttaattcaag tgggcattaa taggccgact tataaaaaat
    10321 tcttgataca acttaaaggg agaaagtttg cacatcgaac aaaatcaatg ttaaaacgat
    10381 aacgtgtata ttgatgacca taaactgcaa tcctatgatg tgacaatatg aggaggataa
    10441 cttaatgaaa cgtgtaataa catatggcac atatgactta cttcactatg gtcatatcga
    10501 attgcttcgt cgtgcaagag agatgggcga ttatttaata gtagcattat caacagatga
    10561 atttaatcaa attaaacata aaaaatctta ttatgattat gaacaacgaa aaatgatgct
    10621 tgaatcaata cgctatgtcg atttagtcat tccagaaaag ggctggggac aaaaagaaga
    10681 cgatgtcgaa aaatttgatg tagatgtttt tgttatggga catgactggg aaggtgaatt
    10741 cgacttctta aaggataaat gtgaagtcat ttatttaaaa cgtacagaag gcatttcgac
    10801 gactaaaatc aaacaagaat tatatggtaa agatgctaaa taaattatat agaactatcg
    10861 atactaaacg ataaattaac ttaggttatt ataaaataaa tataaaacgg acaagtttcg
    10921 cagctttata atgtgcaact tgtccgtttt tagtatgttt tattttcttt ttctaaataa
    10981 acgattgatt atcatatgaa caataagtgc taatccagcg acaaggcatg caccaccaat
    11041 gatagtgaat aatggatgtt cttcccacat acttttagca acagtatttg ccttttgaat
    11101 aattggctga tgaacttcta cagttggagg tccataatct ttattaataa attctcttgg
    11161 atagtccgcg tgtactttac catcttcgac tacaagttta taatcttttt tactaaaatc
    11221 acttggtaaa acatcgtaaa gatcattttc aacataatat ttcttaccat ttatcctttg
    11281 ctcaccttta gacaatattt ttacatattt atactgatca aatgagcgtt ccattaatgc
    11341 attccccatc atattacgtt gcttctcgcc accaaggttt ttatagtctc ctgcacccat
    11401 gataacttga ttaattctaa atttacctcg tttggtagta atcgtatggt tgtaatttgc
    11461 tgtatcactt gatccagttt ttaaaccatc tgtaccaggc aaactcattt ttgcaccttc
    11521 caatgaaaag ttgaatgtgt aatacgtaac tgcatgcgtt gttggtgcta actgctttgt
    11581 aaagtctaat attttaggtg tctctttaat cacgtgtaaa tctaaaatgg catagtctct
    11641 agcagtcgtt acagtacgtt cttggtcttt atactttgtt ggtgcaaatg aacgtaatct
    11701 tgaattttca gcacccgttg gattgacgaa atgtgtattt ttcattccga tagctttagc
    11761 tttgttattc attaaatcaa cgaaatcgct ggtgtttttt gataccttct tagctaaaat
    11821 taatgccgcg gcattactag aattagatac tgtaatttgt aataggtctg cgattgtcca
    11881 tacttgtcca ggatatagtt tcgtattact caactcaggt agtgtagaca taatatattc
    11941 tttgttcgtc attgtgactg tgtcatcaag tgaaagctgc cccttattta cagcttccaa
    12001 tgttaagtac attgtcatta atttagtcat agacgctgga ttccacttag tatcgatatt
    12061 gtattgatac agtaattgtc cagtttgact tacattaaca gcactcgtcg gttcgtatgc
    12121 agccgacaaa cctgcataac catattgatt tgctgcttgt acaggggtta cgtcactgtt
    12181 agtagcttgt gcatatggtg tcataatact taatgttaaa cataaaatga tgataataga
    12241 tattaaattt ttcataaagc gttaatcttc ccttttccaa ttcttaaata ttccctaaaa
    12301 gcaatggtta ttcctactta cggaaatcat tgctaattca cttcacctta attaaattgt
    12361 tgaaaataaa gttttctgca gttaatttga aaaataatgc aaatatatta cgtgtgtagc
    12421 taaaggtgtt ataatgtttg tacgaagagc aaacttactc aaaagcgatt aattttcatg
    12481 ttttaatata aagactttga gaagttatta caaaaaatgc aatagaaata ttctatcata
    12541 taaatgttat gagcggtatt ttggggcaac actttatttg atttttaaag ttttgttggg
    12601 agaaagtata tgatagaaat gcatgtatct atctaaatga attaactata aatttcaaac
    12661 agaagaggta aaactatgaa acgagaaaat ccattgtttt tcttatttaa aaaactatca
    12721 tggccagtgg gtcttatcgt tgcagctatc actatttcat cactagggag cttaagtgga
    12781 ctattagtgc cactgtttac tggacgaatt gtagataaat tttccgtgag ccatatcaat
    12841 tggaatctaa tcgcattatt tggtggtatc tttgtcatca atgctttatt aagcggatta
    12901 ggtttatatt tattaagtaa aattggtgaa aagattattt atgcgatacg ctcagtttta
    12961 tgggagcata tcatacaatt aaaaatgcca ttctttgaca aaaatgaaag tggtcaatta
    13021 atgagtcgat taactgacga tacgaaagtg ataaatgaat ttatttcaca aaagctacct
    13081 aacttattac catcaatcgt tacattagtt gggtcactaa tcatgttatt tattttagat
    13141 tggaaaatga cattattaac atttataacg ataccgatat tcgttttaat tatgattcct
    13201 ctaggtcgta ttatgcaaaa gatatcgaca agtacacaat ctgaaattgc aaacttcagt
    13261 ggtttgttag ggcgtgtcct aactgaaatg cgtcttgtta aaatatcaaa tacagagcgt
    13321 cttgaattag ataatgcaca taaaaatttg aatgaaatat ataaattagg tttaaaacag
    13381 gctaaaattg cggcagttgt acaaccaatt tcaggtatag ttatgttgct aacaattgca
    13441 attattttag gttttggtgc attagaaatt gcgactggtg caatcactgc aggtacatta
    13501 attgcaatga tattttatgt tattcagtta tctatgcctt taatcaatct ttccacgtta
    13561 gttacagatt ataaaaaggc agtcggtgca agtagtagaa tatacgaaat catgcaagaa
    13621 cctattgaac cgacagaagc tcttgaagat tctgaaaatg tattaattga tgacggtgta
    13681 ttgtcatttg aacatgtaga ctttaaatat gatgtgaaga aaatattaga tgatgtgtcg
    13741 ttccaaatcc cacaaggtca agtgagtgct tttgtaggtc cttctgggtc tggtaaaagt
    13801 acgatattta atctgataga acgtatgtat gaaattgagt caggtgatat taaatatggc
    13861 cttgaaagtg tctatgatat cccgttatct aagtggcgac gcaaaattgg atatgttatg
    13921 caatcaaatt cgatgatgag tggaacaatt agagacaata ttttatacgg aattaatcgt
    13981 catgtttcag atgaagaact tattaattat gctaaattag cgaactgtca tgattttatc
    14041 atgcaatttg atgaaggata tgacacgctt gtaggtgaac gaggattgaa actgtctggc
    14101 ggacaacgtc aacgtattga tattgctaga agttttgtta aaaatcctga tattttgtta
    14161 cttgatgaag caacagctaa tctcgatagt gaaagtgaat tgaaaattca agaagcttta
    14221 gaaacattga tggaaggtag aacaacgatt gtcattgcgc atcgtttgtc tacaattaaa
    14281 aaagccggtc aaattatatt cttagacaaa ggacaggtaa caggtaaagg tacgcattca
    14341 gaactgatgg catcacatgc gaagtataaa aactttgtag tgtctcaaaa attaacagat
    14401 taattttata tataagtaag cttggagcaa atacacatat accatcgagg aaattaaagt
    14461 gtggcacatt gatggatata gatgttaata aattgcttca agcttttgt
//
LOCUS       DAPDIM010000065        14290 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000065 DAPDIM010000000
VERSION     DAPDIM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 14290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14290
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.065"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(59..220)
                     /locus_tag="RFE25_002221"
     CDS             complement(59..220)
                     /locus_tag="RFE25_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817257.1"
                     /translation="MLLILELRFWNLEFGFRNSTFGIQNYNEWKILIIACLMTWFCSD
                     FYLMNCFFV"
     gene            complement(257..997)
                     /locus_tag="RFE25_002222"
     CDS             complement(257..997)
                     /locus_tag="RFE25_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDU2817258.1"
                     /translation="MFILRNDLETLKHIIDSSNRITFFTGAGVSVASGVPDFRSMGGL
                     FDEISKDGLSPEYLLSRDYLEDDPEGFINFCHKRLLFVDTKPNIVHDWIAKLERNQQS
                     LGVITQNIDGLHSDAGSQHVDELHGTLNRFYCNACHKSYTKSDVIDRTLKHCDNCGGA
                     IRPDIVLYGEMLDQPTIIRALNKIEHADTLVVLGSSLVVQPAAGLISHFKGDNLIIIN
                     KDRTPYDSDATLVIHDDMVSVVKSLMTE"
     gene            1203..1994
                     /locus_tag="RFE25_002223"
     CDS             1203..1994
                     /locus_tag="RFE25_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDU2817259.1"
                     /translation="MTHRLNKGGNFTLNKHERLDEIAKLVNKKGTIRTNEIVEGLNVS
                     DMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRYIARKAASL
                     IEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMR
                     HITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYL
                     LIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD"
     gene            2361..2789
                     /gene="lacA"
                     /locus_tag="RFE25_002224"
     CDS             2361..2789
                     /gene="lacA"
                     /locus_tag="RFE25_002224"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HDU2817260.1"
                     /translation="MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDAT
                     LAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMI
                     TMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC"
     gene            2805..3320
                     /gene="lacB"
                     /locus_tag="RFE25_002225"
     CDS             2805..3320
                     /gene="lacB"
                     /locus_tag="RFE25_002225"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HDU2817261.1"
                     /translation="MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPI
                     FGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNAN
                     VIGFGGRIIGELLMCDIIDAFINAEYKATEENKKLIAKIKHLETSNEDQADPHFFDEF
                     LEKWDRGEYHD"
     gene            3333..4265
                     /gene="lacC"
                     /locus_tag="RFE25_002226"
     CDS             3333..4265
                     /gene="lacC"
                     /locus_tag="RFE25_002226"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HDU2817262.1"
                     /translation="MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTR
                     VLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHEGQQTEI
                     LEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPV
                     ILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEW
                     IIVSLGAQGAFAKHNHTFYRVNIPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKK
                     ANTLGMLNAQEAQTGYVNLNNYDELFNQIEVLEV"
     gene            4269..5249
                     /gene="lacD"
                     /locus_tag="RFE25_002227"
     CDS             4269..5249
                     /gene="lacD"
                     /locus_tag="RFE25_002227"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDU2817263.1"
                     /translation="MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEP
                     TVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKG
                     RLPDCLVEWSAKRLKEQGANAVKFLLYYDVDDAEEINIQKKAYIERIGSECVAEDIPF
                     FLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGF
                     AEGEVVYTKEEAAQHFKDQDAATHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLC
                     GRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK"
     gene            5271..5582
                     /locus_tag="RFE25_002228"
     CDS             5271..5582
                     /locus_tag="RFE25_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDU2817264.1"
                     /translation="MNREEVQLLGFEIVAFAGDARSKFLEALTAAQAGDFAKADALIE
                     EGNNCIAEAHRAQTSLLAKEAQGDDIAYSVTMMHGQDHLMTTILLKDLMKHLLEFYKR
                     G"
     gene            5588..7300
                     /locus_tag="RFE25_002229"
     CDS             5588..7300
                     /locus_tag="RFE25_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDU2817265.1"
                     /translation="MMQKLIAQIEKGKPFFEKLSRNIYLRAIRDGFISAMPVILFSSI
                     FLLIAYVPNIFGFKWDKGMEAILMKPYNYTMGLVAFLVAGTTAKSLTDSFNRKLESTN
                     QINFISTMLAAMCGFLFLASDPAKDGGFLSAFMGTKGLLTAFLSAFVTVIVYNFCVKR
                     NITIKMPKEVPPNISQVFKDLIPFSAVIIILYALDLVIRNSFKSNVAEGILKLFEPLF
                     TAADGWIGVTIIFGAFALFWFVGIHGPSIVEPAIAAITYANIEANFKLLQAGEHADKI
                     ITSGTQMFIVTFGGTGATLVVPFMFMWMTKSKRNKAIGRASVVPTFFGVNEPILFGAP
                     LVLNPVFFIPFVLAPIVNVWIFKLFVEVLGMNSFSVNLPWTTPGPLGIIMGTGFGLWS
                     FVLAITLIVVDIIIYYPFLKVYDSEILDEEEGRKESNSDLKEKVAANFDTKKADSILA
                     ASGVSDDAAKASNITEQTNVLVLCAGGGTSGLLANALNKAAEEYHVPVKAAAGGYGAH
                     MDIMKEYQLIILAPQVASNYEDIKQDTDRLGIKLAKTQGAEYIKLTRDGQAALDFVQQ
                     QFEN"
     gene            7318..8730
                     /gene="lacG"
                     /locus_tag="RFE25_002230"
     CDS             7318..8730
                     /gene="lacG"
                     /locus_tag="RFE25_002230"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDU2817266.1"
                     /translation="MTKTLPEDFIFGGATAAYQAEGATNTDGKGRVAWDTYLEENYWY
                     TAEPASDFYNRYPVDLELSEKFGVNGIRISIAWSRIFPNGYGEVNPKGVEYYHKLFAE
                     CHKRHVEPFVTLHHFDTPEVLHKDGDFLNRKTIDYFVDYAEYCFKEFPEVKYWTTFNE
                     IGPIGDGQYLVGKFPPGIKYDFEKVFQSHHNMMVAHARAVKLFKDGGYQGEIGVVHAL
                     PTKYPFDPSNPEDVRAAELEDIIHNKFILDATYLGKYSRETMEGVQHILSVNGGKLNI
                     TDEDYAILDAAKDLNDFLGINYYMSDWMRGYDGESEITHNATGDKGGSKYQLKGVGQR
                     EFDVDVPRTDWDWMIYPQGLYDQIMRVVKDYPNYHKIYITENGLGYKDEFIESEKTVH
                     DDARIDYVRQHLNVIADAIKDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQE
                     RYPKKSAYWYKELAETKEIK"
     gene            8996..9865
                     /locus_tag="RFE25_002231"
     CDS             8996..9865
                     /locus_tag="RFE25_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2817267.1"
                     /translation="MKKIFVIITTLLAVAIIIGSIITVVFSQRQAQTFKIQQQQFVKK
                     PIPTLFLHGFGGSANSEKFMVKQAEKRGVTKDIITAYVSKDGAVTFKGKLRKDAVNPI
                     VKIELENNRQGYLDKNAAWFKNVLTKLQSEYNFDKFNFVGHSMGNLTFAQYMMTYGND
                     KSLPQLNKQVNIAGTFNGVLNMNEDVNEITVDKDGKPSRMNQPYQQLRVLKDIYKGKG
                     IEVLNIYGDLKDGTHSDGRVSNSSSKSLKYLLGNSPKSYRESKYEGEPAQHSQLHENE
                     NVANELIDFLWKK"
     gene            10143..11144
                     /locus_tag="RFE25_002232"
     CDS             10143..11144
                     /locus_tag="RFE25_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDU2817268.1"
                     /translation="MQNKQILFNKIPEGMPQEDTFKIEEIDTPKLESDGVLVQTLYIS
                     VDPYMRGRMTKADSYVQPFEIGKPIVSHVVAKVIDSTLADYKKGDVVVGMLPWRIINH
                     VQADQITKVPTTDVPLDLYLSVLGMPGQTAYHGLLDIGQPKAGDTVVVSAASGAVGSV
                     VGQIAKIKGCRVVGIAGGDKKVNYLTETLGFDAGIDYKKEDFAEALAQAVPDGIDVYF
                     ENVGGTVGDEVFKHLNRFARVPVCGAISSYNHPEADIGPRIQGTLIKKQVMMRGFLVS
                     EFANAFKEASEQLATWVQEGKIQSQVTIEDGFENAPHAFKNLFTGDNFGKQVIKVTE"
     gene            11379..12386
                     /locus_tag="RFE25_002233"
     CDS             11379..12386
                     /locus_tag="RFE25_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDU2817269.1"
                     /translation="MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNP
                     VDTKQRQMKVTQAPRVLGFDAIGTVEAIGPDVTLFSPGDVVFYAGSPNRQGSNATYQL
                     VSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISHNPSENVGKSVLIINGAGG
                     VGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEKEIPLVDY
                     IFCTYNTDLYYNTMIELIKPLGHITTIVAFNEDQDLNALKLKSITFTHEFMFARPIHR
                     TPDMIKQHEYLEDITKNIELGHYQPTTTQVFEGLSPENLYQAHQLLEKQSMIGKLVIN
                     I"
     gene            12694..14256
                     /locus_tag="RFE25_002234"
     CDS             12694..14256
                     /locus_tag="RFE25_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HDU2817270.1"
                     /translation="MKNKSVSLVFWVSLVICTIFVAFGAIFPKQLEKLTQNITTFIAL
                     HFSWYYLLLVLVILFVCVYILFSRYANITLGEEGEDPEFSLPSWFAMLFSAGMGIGLV
                     FWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFH
                     KGYPGLVSATLTPLLGEKAMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFL
                     FNVPSNFTMQVILIVIATILFTWSAWSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTL
                     YILNTFTNGLGNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWWISWAPFVGIFIAR
                     VSKGRTIKEFILGVLFVPALVCFIFFAVFGASAIYLQDNHIADIAKAATETATFATLQ
                     HYPLGFVLSLITLLVIMIFFVTSADSATYVLGMLSSRGDINPKSFVKVSWGIIMALFA
                     IIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLLKSLSEEKPRNSNKVLIKHRDPDI
                     LEYRSSKHIDEN"
BASE COUNT         4991 a         2117 c         2758 g         4424 t
ORIGIN      
        1 taatttttta cgaatgggcc tttagcgatt gaaaatgtta taaagtagca tcccaacatt
       61 aaacaaaaaa acaattcatc aaataaaaat cgctacaaaa ccaagtcatt aaacacgcaa
      121 taattaaaat tttccactca ttataattct gaattccaaa tgtcgaattc cgaaaaccaa
      181 actccaaatt ccaaaaacgc aactccaaaa ttaaaagcat ctccctgtta ctcgggaaat
      241 gctttttacc tactgattac tctgtcatta atgattttac aacggaaacc atgtcgtcat
      301 gtatgaccaa agtagcgtcg ctatcataag gtgttcgatc tttattgata ataattaaat
      361 tgtcgccttt aaaatgtgat attaatcctg cggcaggttg tacaacgagt gatgaaccta
      421 gtacaacaag ggtgtcagca tgttcaattt tatttaatgc ccttatgatg gtaggttgat
      481 ctaacatttc accgtataat acgatgtccg gtcgaatggc accaccacaa ttatcacaat
      541 gtttcaaagt tctatcaata acatctgact tcgtataaga tttatgacat gcattacaat
      601 aaaaacgatt taacgtgcca tgtaattcat caacatgttg acttccagcg tctgagtgca
      661 aaccatcgat attttgcgtg atgacaccta aagattgttg attacgttct aattttgcaa
      721 tccaatcatg aacgatatta ggcttcgtat cgacaaatag taaacgctta tggcagaaat
      781 tgataaaacc ttcaggatca tcttctaaat aatcacggct taacaagtat tctggcgaaa
      841 gtccatcttt tgaaatttca tcaaataagc cacccattga acggaaatct ggaacgccac
      901 ttgcgacaga tacaccagca cctgtgaaaa atgtaatacg attcgaacta tctataatat
      961 gttttaatgt ctctaaatca tttctcaaaa taaacacccc atcaaaataa tgaatgattt
     1021 ataacgtctt ttgcttttat tatagtatat tcattttacg attatcaaaa gcgcagttta
     1081 aacagttctt tttaaaaatg aattatacat ataatcgaac agttaaatta tattagtttt
     1141 tacgcaattt ttattataga ataagcatgt atattaaaat tgatgtctaa acataaagga
     1201 taatgaccca tcgcctaaat aaaggaggca attttacatt gaataaacat gaacgtttgg
     1261 acgaaattgc taaactagtg aataaaaagg gcacgataag aacgaatgaa atcgtcgaag
     1321 gtttaaatgt gtctgatatg acagttcgaa gagatttaat tgagttggaa aataagggca
     1381 ttttaacgaa gattcatggt ggtgcacgca gtaattcaac atttcagtat aaagaaatat
     1441 cacataaaga aaaacatact cgtcaaattg ctgaaaaaag atatatagct aggaaagctg
     1501 catcattaat tgaagatggg gatactttgt ttttcggacc gggaacaaca gtggaactat
     1561 tagcagaaga agtcaatcat catacgctca caattattac gaattgtttg ccggtgtata
     1621 aaattttgtt agaaaaacaa acagcacatt ttcgtgtcta tttaattggt ggtgaaatgc
     1681 gccatattac agaagcattt gtaggtgaaa tggcgaatgc catgttggaa aaactaagat
     1741 ttagcaagat gttctttagt agtaacgcag taaataaagg tgctgtgatg acatctacat
     1801 tagatgaagc ctatacgcaa caattggcac taagtaattc aattgaaaaa tacttgttaa
     1861 tcgatcatac gaaagttggc aaagaagatt ttacatcatt ttgtcagtta aacgaattga
     1921 ctgcagtggt catggactat gaagatgaag aaaaagtaga aacgattaaa acatatattg
     1981 aagtagtcga ctaaattaaa agtataactg cattgttaaa atatgtatct atatgctcat
     2041 aagtgaatgt gaatttgcat tcatttatgg gttatttttt tgcaaattta tgtaaacggg
     2101 aacatcgaca aagttttact acaatttcag acgaatacct aattaaaaca acaccacaat
     2161 aggaatgttc acttattgtt tgaaaatatg tcataaacaa acagattata aacatattat
     2221 gttgatttat tgtttgttta tgtttataat ttaaacgtaa tcaaattgaa agccttttct
     2281 caagattttc ataagctaca aataaatatg tcatatttta agaaaggtat ttcaaaatta
     2341 aagtaaaaag gagtcttatt atggcgatta ttattggttc agatgaagct ggcaaacgat
     2401 taaaagaagt catcaaatca tacttattag acaataaata tgatgttgtt gacgtaacag
     2461 aaggacagga agttgacttt gttgatgcaa ctttggctgt agcaaaagat gttcaaagtc
     2521 aagaaggtaa cttaggtatt gttatcgatg catttggtgc aggtagcttt atggttgcta
     2581 caaaaatcaa aggcatgatt gctgctgaag tatcagatga acgctctgga tatatgacta
     2641 gaggccataa caattcaaga atgatcacta tgggatctga aattgttgga gacacattag
     2701 cgaaaaatgt cgttaaaggt tttgttgaag gtaaatacga tggtggtaga caccaaatcc
     2761 gcgtagatat gcttaataaa atgtgctaag gaggaaaaat tactatgaag attgcattag
     2821 gatgcgacca tattgttaca gatacaaaaa tgcgtgtatc tgaattttta aaatcaaaag
     2881 gacatgaagt cattgacgta ggaacatacg attttacaag aacacattat ccaatttttg
     2941 gtaaaaaagt tggcgaacaa gttgttagcg gtaatgcaga cttaggtgtt tgtatttgtg
     3001 gaacaggtgt tggtattaac aatgctgtaa ataaagtacc tggcgttcgt tcagcactag
     3061 tacgtgatat gacatcagcg ttatatgcta aagaagaatt aaatgcgaac gttattggct
     3121 ttggtggacg tattataggt gagttattaa tgtgcgatat tatcgatgca tttattaacg
     3181 ctgaatataa agcaactgaa gagaacaaaa aattaatcgc taaaattaaa catttagaaa
     3241 caagcaatga agatcaagct gatccacatt tctttgatga attcttagaa aaatgggaca
     3301 gaggcgaata ccacgattaa gggacgacac atatgatttt aactttaaca ttaaatccat
     3361 ccgttgatat ttcatatcca ttaacagcat tgaaattaga tgatgttaat cgtgttcaag
     3421 aagtaagtaa aacagctggt ggtaaaggtt taaatgtaac aagagtactt gcgcaagtag
     3481 gcgagccagt ccttgcgagt ggttttattg gcggtgaatt aggtcaattt attgctaaaa
     3541 aattagatca tgccgacatc aagcatgcat tttataacat taagggtgaa acacgaaact
     3601 gcattgcaat tttacatgaa gggcaacaaa cagaaatttt agagcaggga ccggagattg
     3661 ataatcaaga ggctgcagga tttattaaac attttgaaca attattagaa aaagttgaag
     3721 cagttgctat ttcaggtagc ttacctaaag gattaaatca agattattat gcacaaatta
     3781 ttgaacgatg ccaaaacaaa ggtgtgcctg tgatattgga ctgctcgggt gcaactttgc
     3841 aaacagtttt ggaaaatcca tacaaaccaa cagtcattaa accaaacatt tctgaactat
     3901 atcaattgct taaccagcca cttgatgaaa gtttagaaag tttgaaacag gcagtgtcac
     3961 aacccttatt cgaagggatt gagtggatta ttgtgtcttt aggtgcacaa ggtgcattcg
     4021 ctaagcacaa tcatacattc tatagagtga atattccgac aataaacgta ttaaatccgg
     4081 ttggttcagg tgattctaca gttgctggaa ttacttcagc aattctcaat catgaaaacg
     4141 accacgattt actaaaaaaa gctaatactt taggcatgct gaatgcgcaa gaagcacaaa
     4201 caggatatgt caatttaaat aattatgatg aattattcaa tcaaattgaa gttttagagg
     4261 tgtaaataat gtcaaaatct aatcaaaaaa tcgcatcaat tgaacaatta agtaataacg
     4321 aaggtatcat ttctgcatta gcatttgacc aacgtggtgc tttaaaacga atgatggcta
     4381 aacatcaaac ggaagagcca actgtcgctc aaattgaaca attaaaagta ttggttgcgg
     4441 aagaattaac acaatatgcg tcttcaattt tattagatcc agaatacggt ttaccagcat
     4501 ctgatgcacg taacaaagat tgtggattat tgctagctta tgaaaaaact ggttatgacg
     4561 taaatgctaa aggtcgttta cctgactgtt tagtagagtg gtctgcaaaa cgtttaaaag
     4621 aacaaggtgc aaatgctgtt aaattcttac tttactatga tgttgatgat gctgaagaaa
     4681 ttaacattca aaagaaagca tacattgaaa gaatcggttc agaatgtgtt gcagaagaca
     4741 ttcctttctt cttagaagta ttaacatacg atgacaacat tcctgataac ggtagtgttg
     4801 aattcgcaaa agttaagcct agaaaggtta acgaagcaat gaaattattc tcagaaccac
     4861 gctttaatgt tgatgtattg aaagttgaag taccagtaaa catgaagtat gtagaaggct
     4921 ttgctgaagg tgaagtggtt tatacaaaag aggaagcggc acaacacttt aaagatcaag
     4981 atgcagcaac tcatttacca tacatttact taagtgctgg tgtttctgcg gaattattcc
     5041 aagaaacttt aaaatttgct cacgaagctg gtgctaaatt caacggtgta ctttgtggcc
     5101 gtgctacatg gtctggtgct gttcaagtat acattgaaca aggtgaagat gctgctcgtg
     5161 aatggttacg tacaactggt ttcaaaaata ttgatgactt aaataaagta ttaaaagata
     5221 ctgcgacatc ttggaaacaa agaaaataag tataaaaggg gattaatgct atgaatagag
     5281 aagaagtcca attattaggt tttgaaattg ttgcatttgc aggggatgca cgttctaagt
     5341 ttttagaagc attgacagca gctcaagctg gagattttgc aaaagcagat gcattgattg
     5401 aagaaggaaa caattgcatt gctgaagcgc atagagcaca aacaagcctg ttagctaaag
     5461 aagcgcaagg tgatgatatt gcatacagtg taacgatgat gcatggtcaa gaccatttaa
     5521 tgacaacaat tttactgaaa gatttaatga agcatttatt agaattttat aaaagagggt
     5581 gatgacaatg atgcaaaaat tgatcgcaca aattgaaaaa gggaagccat ttttcgagaa
     5641 attatcacgt aacatatatt taagagccat ccgtgatgga tttatttctg caatgcctgt
     5701 catcttattc tcaagtatct ttctattaat tgcatacgtg ccaaatatat ttggttttaa
     5761 atgggataaa ggcatggaag ccattttaat gaaaccatat aactatacga tggggcttgt
     5821 agcattttta gtagcaggaa cgacagcgaa atctttaaca gattcattta accgtaagct
     5881 agaaagtaca aatcaaatta actttatttc tacaatgcta gcagcgatgt gtggattctt
     5941 gttcttagct tctgatccag ccaaagatgg tggattctta agtgcattta tgggaactaa
     6001 aggtttatta acagcatttt tatcagcatt tgtaactgtt attgtttata acttctgtgt
     6061 gaagcgcaat attacaatta aaatgccgaa agaagtaccg ccgaatattt cacaagtatt
     6121 taaggactta attccatttt cagcggtaat catcattctt tatgcattag atttagtcat
     6181 tcgcaacagc tttaaatcaa atgtagcgga aggtatttta aaattattcg aaccattatt
     6241 tacagcagca gatggatgga ttggtgtcac aattatcttt ggtgcctttg cattattctg
     6301 gtttgtagga attcatggtc catcaatagt agagccagca attgcagcca ttacatatgc
     6361 gaatatcgaa gcgaacttca agttgcttca agctggagaa cacgcagata aaattattac
     6421 atcaggtaca caaatgttta tcgttacttt tggaggtacg ggtgcaacat tggtcgtccc
     6481 gttcatgttt atgtggatga cgaaatctaa acgaaacaaa gcgattggac gtgcatcagt
     6541 tgtaccaaca ttctttggtg taaacgaacc aattttattt ggtgcaccac tagtattgaa
     6601 tcctgtgttc tttattccat ttgtattagc accaattgtt aacgtatgga ttttcaaact
     6661 tttcgttgaa gtgttaggaa tgaatagttt tagtgtaaat ttaccttgga caacaccagg
     6721 tccattgggc attatcatgg gtacaggttt tggtttatgg tcattcgtac tagctattac
     6781 tttgattgtt gtagatatta ttatttacta cccattccta aaagtttatg atagtgaaat
     6841 tcttgatgaa gaagaaggac gtaaagaaag taattcagat ttaaaagaaa aagttgcagc
     6901 aaactttgat acgaaaaaag ctgattcaat tttagcggca agtggtgtat cagacgatgc
     6961 agctaaagct tcaaatatca cagaacaaac aaatgtctta gtactttgtg ccggtggtgg
     7021 tacaagtgga ttattagcca acgcacttaa taaagcagct gaagaatatc atgtgccagt
     7081 gaaagcagca gctggcggat acggcgcaca tatggacatt atgaaagagt accaattaat
     7141 cattttagcg ccacaagttg cgtctaacta tgaagatatt aagcaagata cagatagatt
     7201 aggtattaaa ttagcgaaga ctcaaggtgc tgaatatatc aaattgacac gagacggcca
     7261 agcagccctt gatttcgttc aacaacaatt tgaaaattaa gaataggagt ttttcatatg
     7321 actaaaacat tacctgaaga ttttattttt ggtggagcaa cagcagcata tcaagcagaa
     7381 ggtgcgacaa atacagatgg taaaggtcgt gttgcatggg atacgtattt ggaagaaaac
     7441 tattggtaca ctgcagaacc agcgagtgat ttttataaca gatatccagt ggatttagaa
     7501 ttaagtgaaa aattcggtgt taatggtatc cgtatttcaa ttgcatggtc acgtatcttc
     7561 ccaaatggat atggcgaagt taaccctaaa ggtgttgagt attaccataa gttatttgca
     7621 gagtgtcata aacgtcatgt tgaaccattt gtaacattgc atcattttga tacaccagaa
     7681 gtgttacaca aagatggcga ttttctaaat cgtaaaacga ttgactactt tgtagattat
     7741 gctgaatatt gttttaaaga attcccagaa gtaaaatatt ggactacatt caatgaaatt
     7801 ggacctattg gtgatggtca atatttagta ggtaaattcc ctccaggtat taaatatgat
     7861 tttgaaaaag ttttccaatc acatcacaat atgatggttg ctcatgcaag agcagtaaaa
     7921 ttatttaaag atggcggcta tcaaggagaa attggtgttg tacacgcatt gccaacaaaa
     7981 tatccgttcg atccatcaaa tcctgaagat gttcgtgcag cagaattaga agatatcatc
     8041 cataataaat tcatcttaga tgcaacatat ttaggtaagt attctcgtga aacgatggaa
     8101 ggtgtgcaac atatcttatc tgttaatggc ggtaaattaa atattacaga tgaagattat
     8161 gccattttag atgcagccaa agatttaaac gacttcttag gtatcaatta ctacatgagt
     8221 gactggatga gaggttacga tggagaatct gaaatcacgc ataatgcgac aggtgataaa
     8281 ggcggttcta aataccaact taaaggtgtc ggacaacgtg aatttgatgt cgacgtacct
     8341 cgcacagact gggactggat gatctatcct caaggtttat atgatcaaat catgcgtgtt
     8401 gttaaagatt atcctaacta tcacaagatt tatatcactg aaaatggttt aggatataaa
     8461 gatgaattta ttgaatctga aaaaacagtt catgatgatg cacgtattga ttatgtaaga
     8521 caacatttga acgttattgc agatgctatt aaagatggtg caaatgttaa aggttacttt
     8581 atttggtcat taatggatgt gttctcttgg tcaaatggtt atgaaaaacg atatggttta
     8641 ttctatgtcg attttgagac tcaagaacgt tatcctaaga aaagtgctta ttggtacaaa
     8701 gagttagccg aaacaaaaga aattaaataa ttatagatat taaaaggcct atcagtcgag
     8761 tgctggtagg tctttattta tagaaagaga taaattaaac aagtatatac atatttatat
     8821 attaatcaat gggtgacaca ccattgaaag ctaaagaagc aatcaattaa caaacgttaa
     8881 cggacaactt tccaaagtca tcttaaaagt taatgatgta ttcaaaatca actaaaggac
     8941 atttttaatc acatccttta tacttatata aaagacatga atgggagtta aaagtgtgaa
     9001 gaaaattttt gtaattatta cgacattgtt agcggtcgct attattatag gctctattat
     9061 tacggtggtg tttagtcaac gacaggcaca aacatttaaa atacaacaac agcaatttgt
     9121 taaaaagcca attccaacat tgttcttaca tggatttggt ggtagtgcca attctgaaaa
     9181 gtttatggtg aagcaagcag aaaaaagagg ggtaactaaa gatatcatca ctgcttacgt
     9241 ttcaaaggat ggtgcagtga catttaaagg gaaactaaga aaagatgcag tgaatcctat
     9301 tgtgaaaatt gaacttgaaa ataacagaca aggctatttg gataagaatg ctgcgtggtt
     9361 taaaaatgta ctgactaagt tacaatctga atacaatttc gataaattca actttgtcgg
     9421 tcactcaatg gggaacttaa catttgcaca atatatgatg acatatggta acgacaagtc
     9481 actgccacag ttaaacaaac aagtgaatat tgcagggaca tttaatggtg ttttaaatat
     9541 gaatgaagat gtcaatgaaa ttacagttga taaagatggt aaaccaagtc gaatgaatca
     9601 accttatcag caattacgcg tgctaaaaga tatttataaa ggtaaaggta tcgaagtgct
     9661 aaatatttat ggagatttga aagatggtac acattcagac ggcagagtgt ctaatagttc
     9721 ttcgaaatca ttaaaatatt tactgggaaa tagtccgaaa agttatcgag aatctaaata
     9781 tgaaggtgag cctgcacaac atagtcagct tcatgagaat gaaaatgttg ctaatgagtt
     9841 aatcgacttc ttatggaaaa aataaagcaa ctgctagttt tctggggcaa aaaagcttgt
     9901 aatattagag cttttcaaaa attatctatt gtttgagagt ttccataaaa tgtctaagtc
     9961 gtaacatttt taatttatgt ttacagcaaa tataatgtac ttgaagttaa atgaatcagt
    10021 gcttaagtca aaatataaca actaagaatg tatttgcata cagacatcac gaagacacaa
    10081 ttaaaactta acgcttaagt aacaaataag taaaagtttc aaataaagaa aggtgattaa
    10141 tgatgcaaaa taaacaaatt ctttttaaca aaataccaga aggcatgcct caagaggata
    10201 cattcaaaat tgaagagatt gacacgccta aacttgagag cgatggtgta cttgtacaaa
    10261 cgctgtatat ttcagtggat ccatatatga gaggacgtat gactaaggca gattcgtatg
    10321 tacagccttt tgaaattggt aaaccgattg ttagccatgt cgttgcaaaa gtaattgatt
    10381 cgacactcgc agattataaa aaaggagatg tcgttgtagg tatgttgcct tggcgaatca
    10441 ttaatcatgt ccaagcggat caaattacta aagttccaac gacagatgta ccacttgatt
    10501 tatatttaag tgttttagga atgccaggac aaacagcata tcatggtctg cttgatattg
    10561 gacaacctaa agccggtgat actgttgtgg tttcagctgc atctggtgct gtaggttcag
    10621 ttgtaggtca aattgctaag attaaaggtt gccgtgtagt aggtattgcg ggtggcgaca
    10681 aaaaagtaaa ttatttaaca gagacactgg gctttgacgc tggtattgat tataagaaag
    10741 aggattttgc agaagcgtta gcacaagcag taccagatgg tattgatgtt tattttgaaa
    10801 atgttggtgg tacagttggc gatgaagtat ttaagcattt aaatcgtttt gcacgtgtac
    10861 cagtatgcgg cgcaatttcg tcatataatc atcctgaagc agatatcgga ccacgtattc
    10921 aaggtacgct tattaagaag caagtaatga tgagaggctt cttagtaagt gaattcgcta
    10981 atgcttttaa agaagctagt gaacagctcg caacatgggt tcaagaaggt aaaattcagt
    11041 cacaagtaac cattgaagat ggttttgaaa atgcgccaca tgcatttaaa aatttattta
    11101 ctggcgataa ctttggtaaa caagttatta aagtaacgga ataataaagt atacgtttta
    11161 acaaactaac tttgttaatt gatcaaaatt taataacttt cttatctaaa gcaaatttgt
    11221 tcagtaacat ggtagaaata agtctaaaat gtaatacgaa agtcgtctgt aattatttat
    11281 atattcaaat gaaaaaggag tcatgatgct gcggtataag cacacatggc ttctattttg
    11341 tataataaga aataagttca taaatgaggt gaaacgatat gaaaatgata ggatttgaaa
    11401 agccctttaa attggaagaa ggaaatttat ttaaagtata cgaacaaaga aagccaacgc
    11461 cagaaaacga tgatatctta gtcaaagtaa atagtattag tgtaaatcct gtagatacaa
    11521 aacaacgtca aatgaaagtc actcaagcac ctcgtgtact tgggtttgat gctattggta
    11581 ctgttgaagc tatcggacca gacgttacat tatttagtcc gggtgacgtt gtattttatg
    11641 ctggatcgcc aaatagacaa ggatcaaatg cgacatatca attggtgtca gaagctatag
    11701 ttgcaaaggc accacacaac ataagtgcta atgaagcggt tagtctaccg ctaactggta
    11761 ttacggcata tgaaacgttt tttgatacat ttaaaatttc acataatcct tctgaaaatg
    11821 taggtaaatc cgtgttaatc attaatggtg ccggtggtgt aggcagtata gccactcaaa
    11881 ttgctaaacg gtatggttta actgtcatta caacagcatc acgacaagaa acaacagagt
    11941 ggtgtgaaaa gatgggcgca gatatcgtat tgaatcataa agaggattta gtgcgtcaat
    12001 ttaaagaaaa agaaattcca ttagtagatt atatattttg cacttataat acagacttgt
    12061 attacaatac tatgattgaa ctgataaaac cattagggca tattacgact atcgtagctt
    12121 ttaatgaaga tcaagattta aatgcattaa aattaaaaag tataacattt acacatgaat
    12181 ttatgtttgc gcgtccaatt catcgaacgc ctgatatgat taaacaacat gagtatttag
    12241 aagatattac gaaaaatata gaattagggc attaccaacc aacaacgaca caagtttttg
    12301 aaggtttatc acctgaaaac ttatatcaag cacatcaatt gttggaaaaa caatcaatga
    12361 ttgggaaatt agtaattaat atatagatta gtaagtaaag tcgccttatg cagaaaatac
    12421 tgtatagggc gacttatttt ttgtgtctag cgactattga ttctaaacgg aaatatggca
    12481 actttacagg tatcaaatca ataatgcact agaaaggcat tacttaaata caataaaata
    12541 ctttgttgct caatgataaa taatttgagt gtgttttata tatcattttt aaaagatgag
    12601 gcattattaa ttgtgtctat ataaaattac aaatgattaa aatgttgcag ttatgggtat
    12661 gaacttacca ttacacagaa agggtttgta tttatgaaaa ataaatcagt aagtctagtg
    12721 ttttgggtat ctttagtgat atgtacgata tttgttgctt ttggagcaat atttccgaaa
    12781 caattagaaa aactcacgca aaacattact acatttattg cgctacattt ttcttggtat
    12841 tatttattgc tcgttttagt tattttattt gtctgtgtgt atattttatt ttcgagatac
    12901 gcaaacatta cattaggtga agaaggcgaa gatcctgaat tctcattgcc gtcttggttt
    12961 gctatgttat ttagtgctgg tatgggaata ggacttgtgt tctggacaac ggcagaacca
    13021 atcagtcatg ccttcaaatt aacgcctatt cataaagctg gcacgcaatc tgcaattaat
    13081 gatgcaatgc agttttcatt tttccattgg gggattcatg catgggcagt ctatggtatt
    13141 gtcgcgcttg tgtttgcata ttttagcttt cataaaggat atcctggctt agtcagcgct
    13201 acattgacgc ctttattagg tgaaaaggca atgcgtggac ctttaggtgg tgccattgat
    13261 gtattggcag tcatagctac agtaacaggc gttgctgcaa cattaggttt cggtgcattg
    13321 caaataaacg aaggtttaca ttttttattt aatgtaccga gtaacttcac gatgcaagta
    13381 atcttgattg tcattgcaac catattattt acttggtcag catggtcagg tatcgataaa
    13441 ggtatcaaaa cgttgagtaa tatcaacatg ttacttgctt ttgtagtact tattggtctt
    13501 tttattgttg ggccaacgct ttacatttta aatacattta caaatggtct aggtaattat
    13561 attgcaaatt tctttagtat gagtttacgt attccgtcag gcggtcaaaa attccaatgg
    13621 ttacaaaatt ggacaatctt ttactgggca tggtggatat cttgggcacc atttgtaggt
    13681 atatttattg cacgtgtgtc aaaaggacgt acgattaaag aatttattct aggtgtactt
    13741 tttgtcccgg cgttagtttg ctttatattc tttgcggtat tcggcgcgtc agcaatttac
    13801 ttacaagata atcatattgc cgatattgct aaagcagcga cagaaacagc aacttttgca
    13861 acgctacaac attacccact aggttttgta ttaagcttaa ttactttact tgttattatg
    13921 attttctttg ttacatcagc ggattcggca acttatgttt taggtatgtt gagttcaaga
    13981 ggtgatatta atccgaagtc atttgtcaaa gtgagttggg gtatcattat ggcattattt
    14041 gcaattatca tgatctacac aggtggtact caagcgattc aaaatttatt aatcattgct
    14101 gcgttaccat tttccgtggt cattatagcg atgatatggt cgcttttaaa atctttaagt
    14161 gaagaaaaac ctagaaatag taataaggtt ttaattaaac atcgtgaccc agatatttta
    14221 gaatatcgtt cttcaaaaca tattgacgaa aattaattaa taatgaggtt ttatttacaa
    14281 aaactaggga
//
LOCUS       DAPDIM010000066        14107 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000066 DAPDIM010000000
VERSION     DAPDIM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 14107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14107
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.066"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            178..1737
                     /gene="rny"
                     /locus_tag="RFE25_002235"
     CDS             178..1737
                     /gene="rny"
                     /locus_tag="RFE25_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002459258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDU2817271.1"
                     /translation="MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVN
                     QAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSD
                     LLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQ
                     RVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPND
                     EMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDG
                     RIHPGRIEDMVEKARKEVDDIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQN
                     VLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKY
                     GENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETL
                     SESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTV
                     VRETRAVEYAK"
     gene            complement(2034..2249)
                     /locus_tag="RFE25_002236"
     CDS             complement(2034..2249)
                     /locus_tag="RFE25_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817272.1"
                     /translation="MSINIDPEKFAELVVMSNPSKFEDAEDIAKESLKLYINAYRLAE
                     RYSTIATNCYDTAEVIKELKKTDLQLK"
     gene            2423..3220
                     /locus_tag="RFE25_002237"
     CDS             2423..3220
                     /locus_tag="RFE25_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HDU2817273.1"
                     /translation="MRIMFIGDIVGKIGRDAIETYIPQLKQKYKPTVTIVNAENAAHG
                     KGLTEKIYKQLLRNGVDFMTMGNHTYGQREIYDFIDEAKRLVRPANFPDEAPGIGMRF
                     IQINDIKLAVINLQGRAFMPDIDDPFKKADQLVKEAQEQTPFIFVDFHAETTSEKYAM
                     GWHLDGRASAVVGTHTHIQTADERILPKGTGYITDVGMTGFYDGILGINKTEVIERFI
                     TSLPQRHVVPNEGRSVLSGVVIDLDKEGKTKHIERILINDDHPFSTF"
     gene            3360..5120
                     /locus_tag="RFE25_002238"
     CDS             3360..5120
                     /locus_tag="RFE25_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="HDU2817274.1"
                     /translation="MKPQLSWKVGGQQGEGIESTGEIFATAMNRKGYYLYGYRHFSSR
                     IKGGHTNNKIRVSTTPVHAISDDLDILIAFDQETIDVNHHEMREDSIILADAKAKPVK
                     PEGCHAQLIELPFTATAKELGTALMKNMVAIGATSALMNLNTNTFEELITNMFSKKGD
                     KVVEVNIQALNEGYQLMQSRLPEIDGDFELESTDALPHLYMIGNDAIGLGAIAAGSQF
                     MAAYPITPASEVMEYMIANISKVNGAVIQTEDEIAAVTMAIGANYGGVRAFTASAGPG
                     LSLMMEAIGLSGMTETPLVIINTQRGGPSTGLPTKQEQSDLMQMIYGTHGDIPKIVVA
                     PTDAEDAFYLTMEAFNLAEQYQCPVIVLSDLQLSLGKQTVEKLDYNRIEIKRGEIIQS
                     DIEREEDDKGYFKRYALTSNGVSPRPIPGVKGGIHHITGVEHNEEGKPSESASNRQQQ
                     MEKRMRKIEQLLIESPVEANLQHEDADILYIGFISTKGAIQEGSNRLNQQGIKVNTIQ
                     IRQLHPFPTSVIQDAVNKAKKVVVVEHNYQGQLASIIKMNVNIHDKIENYTKYDGTPF
                     LPHEIEEKGKIIATEIKEMV"
     gene            5121..5987
                     /locus_tag="RFE25_002239"
     CDS             5121..5987
                     /locus_tag="RFE25_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit
                     beta"
                     /protein_id="HDU2817275.1"
                     /translation="MATFKDFRNNVKPNWCPGCGDFSVQAAIQKAAANIGLEPEEVAI
                     ITGIGCSGRLSGYINSYGVHSIHGRALPLAQGVKMANKDLTVIASGGDGDGYAIGMGH
                     TIHALRRNMNMTYIVMDNQIYGLTKGQTSPSSAVGFVTKTTPKGNIEKNVAPLELVLS
                     SGATFVAQGFSSDIKGLTKLIEDAINHDGFSFVNVFSPCVTYNKINTYDWFKEHLTSV
                     DDIENYDSTDKQLATKTVIEHESLVTGIVYQDKETPSYESQIKELDDTPLAKRDIKIT
                     EDTFNALTEQFI"
     gene            6081..6374
                     /locus_tag="RFE25_002240"
     CDS             6081..6374
                     /locus_tag="RFE25_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HDU2817276.1"
                     /translation="MKDTLMSIQIIPKTPNNDNVIPYVDEAIKIIDESGLHFRVGPLE
                     TTVQGNMNECLILIQSLNERMVELECPSIISQVKFYHVPDGITIETLTEKYDE"
     gene            6508..8052
                     /gene="miaB"
                     /locus_tag="RFE25_002241"
     CDS             6508..8052
                     /gene="miaB"
                     /locus_tag="RFE25_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDU2817277.1"
                     /translation="MNEEQRKASSVDVLAERDKKAEKDYSKYFEHVYQPPNLKEAKKR
                     GKQEVRYNRDFQIDEKYRGMGNERTFLIKTYGCQMNAHDTEVIAGILEALGYQATTDI
                     NTADVILINTCAIRENAENKVFSEIGNLKHLKKERPDILIGVCGCMSQEESVVNKILK
                     SYQNVDMIFGTHNIHHLPEILEEAYLSKAMVVEVWSKEGDVIENLPKVREGNIKAWVN
                     IMYGCDKFCTYCIVPFTRGKERSRRPEDIIDEVRELAREGYKEITLLGQNVNSYGKDL
                     QDIEYDLGDLLQAISKIAIPRVRFTTSHPWDFTDHMIDVISEGGNIVPHIHLPVQSGN
                     NAVLKIMGRKYTRESYLDLVKRIKDRIPNVALTTDIIVGYPNESEEQFEETLTLYDEV
                     GFEHAYTYLYSQRDGTPAAKMKDNVPLNVKKERLQRLNKKVGHYSQIAMSKYEGQTVT
                     VLCEGSSKKDDQVLAGYTDKNKLVNFKAPKEMIGKLVEVRIDEAKQYSLNGSFVKEVE
                     PEMVIQ"
     gene            8053..8418
                     /locus_tag="RFE25_002242"
     CDS             8053..8418
                     /locus_tag="RFE25_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
                     /protein_id="HDU2817278.1"
                     /translation="MYNKDDVLKQADNIANKIKNLDTIKTYQQIEAQIHQNQTIKTKM
                     DMLKKHQKQAVNFQNYGKQNALEQSEHTIQSIEAEINTLPIVEQFQTSQYEANQLLKM
                     FVSTMETRLNDHNKAKHSD"
     gene            8445..8936
                     /gene="thiW"
                     /locus_tag="RFE25_002243"
     CDS             8445..8936
                     /gene="thiW"
                     /locus_tag="RFE25_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HDU2817279.1"
                     /translation="MKSRKLAITALLIAINVVLSSIIIIPLGPVKAAPVQHFVNVLSA
                     VIVGPWYGLAQALISSILRVLFGTGTAFAFPGSMIGVLLASMFYIYRKHIFMAAVGEV
                     LGTGVIGSLICIPLAYFLGLQDFFIKPLMITFIVSSAIGSIISYFLLITLKKRGILQR
                     FIK"
     gene            9239..11857
                     /gene="mutS"
                     /locus_tag="RFE25_002244"
     CDS             9239..11857
                     /gene="mutS"
                     /locus_tag="RFE25_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDU2817280.1"
                     /translation="MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRV
                     LEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNNGYKVAICEQMEDPKQTKGMVRR
                     EVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
                     LNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQAT
                     QLLLDYIHHTQKRDLSHIEDVVQYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWL
                     MDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIERDTLRTYLNQVYDIE
                     RLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILE
                     QSLVEEPPISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKIS
                     FNKVFGYFIEITRANLQNFEPSEFGYMRKQTLSNAERFITDELKEKEDIILGAEDKAI
                     ELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFSENKTLE
                     LVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQM
                     GAYVPCKEAVLPIFDQIFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDE
                     IGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHELTTLDQALPSLKNVHVAANEY
                     KGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLK
                     MVENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMT
                     PIEALVKLSELQNQLK"
     gene            11870..13879
                     /gene="mutL"
                     /locus_tag="RFE25_002245"
     CDS             11870..13879
                     /gene="mutL"
                     /locus_tag="RFE25_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDU2817281.1"
                     /translation="MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEIS
                     IEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALAS
                     ISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
                     KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVAR
                     DLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLT
                     IGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKN
                     NLDYVPKKNKVLYSFEQQKIEFEQRQNTENNQEKTFSSEESNSKSFMAENQNDEIVIK
                     EDSYNPFVTKTSESLITDDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNEDASVQ
                     NYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAA
                     QERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGG
                     HDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHY
                     LQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM"
     gene            13885..>14107
                     /locus_tag="RFE25_002246"
     CDS             13885..>14107
                     /locus_tag="RFE25_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HDU2817282.1"
                     /translation="MNQVNNNILPAIRNIKDLEKLIKTDYKMCVLLDMHIGHIKSIME
                     LLKQNHIECFIHIDLIKGLSHDEFASEFII"
BASE COUNT         5352 a         1915 c         2649 g         4191 t
ORIGIN      
        1 cttcaaaact ttagaaaata gtagaaatag cattcaatat agtgcaaaag tgcaaattga
       61 taacttgaca cttatctcct ataaaccgta caattaattt gtatgattta tatataattt
      121 cataaagtca tattgaattt catataaaga gcaaacccta gaaaaggagg tgtttgtgtg
      181 aatttattaa gcctcctact cattttgctg gggatcattc taggagttgt tggagggtat
      241 gttgttgccc gaaatttgtt gcttcaaaag caatcacaag ctagacaaac tgccgaagat
      301 attgtaaatc aagcacataa agaagctgac aatatcaaaa aagagaaatt acttgaggca
      361 aaagaagaaa accaaatcct aagagaacaa actgaagcag aactacgaga aagacgtagc
      421 gaacttcaaa gacaagaaac ccgacttctt caaaaagaag aaaacttaga gcgcaaatct
      481 gatctattag ataaaaaaga tgagatttta gagcaaaaag aatcaaaaat tgaagaaaaa
      541 caacaacaag tagatgcaaa agagagtagt gttcaaacgt taataatgaa gcatgaacaa
      601 gaattagaac gcatctccgg tctcactcaa gaagaagcta ttaatgagca acttcaaaga
      661 gtagaggaag aactgtcaca agatattgca gtacttgtta aagaaaaaga aaaagaagct
      721 aaagaaaaag ttgataaaac agcaaaagaa ttattagcta cagcagtaca aagattagca
      781 gcagatcaca caagtgaatc aacggtatca gtagttaact tacctaatga tgagatgaaa
      841 ggtcgaatca ttggacgaga aggacgaaac atccgcacac ttgaaacttt aactggcatt
      901 gatttaatta ttgatgacac accagaagcg gttatattat ctggttttga tccaataaga
      961 agagaaattg ctagaacagc acttgttaac ttagtatctg atggacgtat tcatccaggt
     1021 agaattgaag atatggtcga aaaagctaga aaagaagtag acgatattat tagagaagca
     1081 ggtgaacaag ctacatttga agtgaacgca cataatatgc atcctgactt agtaaaaatt
     1141 gtagggcgtt taaactatcg tacgagttac ggtcaaaatg tacttaaaca ttcaattgaa
     1201 gttgcgcatc ttgctagtat gttagctgct gagctaggcg aagatgagac attagcgaaa
     1261 cgagctggac ttttacatga tgttggtaaa gcaattgatc atgaagtaga aggtagtcat
     1321 gttgaaatcg gtgtagaatt agcgaaaaaa tatggtgaaa atgaaacagt tattaatgca
     1381 atccattctc accatggtga tgttgaacct acatctatta tatctatcct tgttgctgct
     1441 gcagatgcat tgtctgcggc tcgtccaggt gcaagaaaag aaacattaga gaattatatt
     1501 cgtcgattag aacgtttaga aacgttatca gaaagttatg atggtgtaga aaaagcattt
     1561 gcgattcagg caggtagaga aatccgagtg attgtatctc ctgaagaaat tgatgattta
     1621 aaatcttatc gattggctag agatattaaa aatcagattg aagatgaatt acaatatcct
     1681 ggtcatatca aggtgacagt tgttcgagag actagagcag tagaatatgc gaaataattt
     1741 ttgtctccct cacaaattag tgagggagct tttttaagtt gtagtctcaa tctaattaga
     1801 cagcacttta tcggtaataa ctatagtaaa cagtggttat ttgaaagtaa gacggacctt
     1861 atattaaata agaagttatt gcttttaata aaaatgtttt aggcttcgta tttactatat
     1921 ttatattatg taaacctata aagatgagtg cttttctaac caataaaaaa gaagagaaga
     1981 tgtaacacat cttctcttct gcaatattaa ttaggattta tttctaagtt gagttatttt
     2041 aattgtaaat ctgttttctt taattctttt ataacttctg cagtatcata acaatttgtt
     2101 gcaattgttg aatatctctc tgctaaacga tatgcattaa tgtaaagctt taaactttct
     2161 ttagctatat cctctgcatc ttcgaatttt gatgggttag acataaccac taattctgca
     2221 aatttttctg gatcaatatt aatagacatg tatttattta caactcctat ttattttgat
     2281 gtcttaatac taacatattg aagttttcag acaaagtaat gtctctctat aattgaagaa
     2341 aaataattca aagaatttaa tatttacttt aaatattaga acgtatgaat taaactagta
     2401 tttatgagag gatgaacaaa acatgagaat aatgtttata ggggatatcg taggtaaaat
     2461 tggacgagac gcaattgaaa cgtacatacc tcaactgaag caaaagtata aaccaacagt
     2521 tacaattgta aatgctgaaa atgcagcaca tggtaaaggt ttgactgaaa aaatatataa
     2581 acaattacta agaaatggtg tagatttcat gactatgggt aatcacacat atggtcaacg
     2641 tgaaatttat gattttatag atgaagcaaa acgactagta agaccagcga attttccgga
     2701 tgaagcgccg ggaattggta tgagatttat acaaattaat gatattaaac ttgcagttat
     2761 taatctgcaa ggaagagcgt ttatgccaga tattgatgat ccttttaaaa aggcagatca
     2821 attagtcaag gaagcacaag aacaaactcc gtttatattt gttgattttc atgcagaaac
     2881 aacttctgaa aagtatgcaa tgggatggca tttagatggt agagctagcg ctgttgttgg
     2941 aacgcataca cacattcaaa cagcagatga acgtatttta ccaaagggga cagggtatat
     3001 aacggatgtt ggtatgacag gtttttatga cggcatttta ggaataaata aaacagaggt
     3061 aattgagcgt tttatcacta gtttgccaca aagacatgtt gttccaaatg aaggtagaag
     3121 tgtattatct ggtgttgtta ttgatttaga caaagaaggt aaaacaaagc acatcgaacg
     3181 tatattgata aatgatgacc atccattttc aacattttaa aattacgtaa gtaaacattc
     3241 gaattggacc ctatcgtcca ttagtatgaa tttaatatag taccactgtt tacatagtaa
     3301 atcggtggtt ctttttgtta tcatttaata tgaaatatat ccataggagg catataacta
     3361 tgaaaccaca attatcgtgg aaagttggcg gtcaacaagg cgaaggtatt gaatcaactg
     3421 gggaaatctt cgctacggct atgaatagaa aaggatatta tttatatgga tatagacatt
     3481 tttcaagtcg tatcaaaggt ggacatacga ataataaaat tagagtttct acgacgcctg
     3541 ttcatgcaat tagtgatgat ttagatattt tgattgcatt tgaccaagaa acaattgatg
     3601 ttaaccatca tgaaatgaga gaagacagta ttattttagc tgatgccaag gctaaacctg
     3661 tgaaaccaga aggatgtcat gcacagctta ttgaattacc ttttacagca accgctaaag
     3721 aattaggtac agcattaatg aaaaacatgg ttgcaatagg tgctactagc gcattgatga
     3781 atttgaatac aaatacattt gaagaactta ttactaatat gttttctaaa aaaggtgaca
     3841 aggtagttga agtcaatatc caagcattaa acgaaggtta tcaattaatg caatcccgct
     3901 tacctgaaat cgacggggac tttgaattag agtcaacaga tgcactacca catctatata
     3961 tgattggtaa cgatgccatt ggattaggtg caattgctgc aggttcacaa tttatggcgg
     4021 catatcctat tacacctgcg tctgaagtta tggaatatat gattgccaat atatctaaag
     4081 taaacggagc ggttattcaa acagaagatg aaattgctgc tgtaactatg gctattggtg
     4141 caaattatgg tggagtcaga gcgtttacgg ctagtgctgg tccaggttta tctttaatga
     4201 tggaagcaat tggattatct ggtatgactg aaacgccatt agtcattatt aatactcaac
     4261 gaggtggacc ttctactgga ttacctacga aacaagaaca gtcagattta atgcaaatga
     4321 tttatggtac acatggtgat attccaaaaa tagttgtagc accaactgat gcagaagatg
     4381 cattttattt aactatggaa gcctttaatt tagcagaaca atatcaatgc cctgttatag
     4441 ttttaagtga tttgcaatta tctttaggta aacaaactgt tgaaaaatta gattataatc
     4501 gcattgaaat taaacgtggt gaaatcattc aatctgatat tgaacgtgaa gaagatgata
     4561 aaggttattt caagcgttat gcgttaacat ccaatggtgt ttctcctaga cctatccccg
     4621 gtgttaaagg aggtattcat catataactg gtgtggaaca caatgaagaa ggtaaaccta
     4681 gtgaatctgc gtcaaataga caacaacaaa tggaaaaacg aatgcgtaaa attgagcagt
     4741 tactaattga atcgccagta gaagctaact tacaacatga ggatgcagat attctttata
     4801 tcggttttat ttctacaaaa ggtgcaattc aagaaggtag taaccgtttg aatcaacaag
     4861 gcataaaagt taacactata caaattagac aattgcatcc attcccaaca agcgttattc
     4921 aagatgcagt taataaagcg aagaaagtcg ttgtagtgga gcacaattat caaggacaat
     4981 tggctagtat tataaaaatg aatgtcaata ttcatgataa gattgaaaat tatacaaagt
     5041 atgatgggac acctttccta ccacatgaaa tcgaagaaaa aggcaaaata attgctactg
     5101 aaataaagga gatggtatag atggcgacat ttaaagattt tagaaataat gttaagccta
     5161 actggtgccc cggatgtggc gatttctcag tacaagctgc aattcaaaaa gcagccgcaa
     5221 atatagggtt agaacctgaa gaagtagcta tcatcaccgg tataggatgt tctggccgtc
     5281 tttcaggata tattaattct tatggcgttc attctattca cggacgtgca ttacctttag
     5341 ctcaaggtgt aaaaatggcg aataaagatt taactgttat tgcatcggga ggagatggtg
     5401 atggttatgc tataggtatg gggcatacaa tccatgcttt aagaagaaat atgaacatga
     5461 cgtatatagt catggataat caaatttatg gtttgacaaa gggacaaaca tcgccgtcat
     5521 cagcagtagg atttgttact aaaacaacgc caaaaggtaa tatagaaaaa aatgttgcgc
     5581 ctttagaatt agtattatca tctggtgcca catttgtagc ccaaggtttt tcaagcgata
     5641 ttaaaggatt aacaaaacta attgaagatg caattaatca tgatggattt tcattcgtta
     5701 atgtcttttc accatgtgtg acttataata aaattaacac atacgattgg tttaaagaac
     5761 atttaacaag tgttgatgac attgaaaatt atgattctac agataaacaa ttagcgacta
     5821 aaactgttat tgaacatgaa tctttagtaa ctggtattgt ttatcaagat aaagaaacac
     5881 catcatatga atctcaaatt aaagagttag atgatacacc acttgctaaa agagatatca
     5941 aaattactga agacaccttc aatgcattaa ctgaacaatt tatttaataa ttaaaactga
     6001 gtcgtataaa tgtatttata acagatccat ttatgctact cagtttttta ctattacaaa
     6061 aaataaagga gtttttaaaa atgaaagaca cattaatgag tatacaaata attcctaaaa
     6121 caccaaacaa tgacaatgtt ataccttacg tagacgaggc gattaaaata attgacgaat
     6181 ctggtttgca ttttagagta ggtccgttag aaacgacagt acaaggaaat atgaatgaat
     6241 gtttaatttt aatacaatca ttaaatgaac gaatggtgga acttgaatgt ccaagtatta
     6301 ttagccaagt taagttttat catgtgccag atggcatcac tattgaaact ttaactgaaa
     6361 aatatgatga ataacattaa aagtgaagta aactggattt gaattggctt gttagagatg
     6421 acgtataact ttaactgttt ttgcacttta tagttaaatt taatataatt attaaatgat
     6481 acgggcaaat agaaaggatt ttgtaaagtg aacgaagaac aaagaaaagc aagttctgta
     6541 gatgttttag ctgagagaga taagaaagca gaaaaagatt atagtaaata ttttgaacat
     6601 gtttatcagc cgcctaattt aaaagaagcg aaaaaaagag gtaaacaaga agttcgttat
     6661 aatagagatt tccaaattga tgaaaaatat cgcggtatgg ggaacgagcg tacattttta
     6721 attaaaacat atggatgtca aatgaatgca catgacactg aggtcattgc tggtatactt
     6781 gaagcattag gctatcaagc aacgactgat attaacactg cagatgttat tttaattaat
     6841 acatgtgcga ttagagaaaa tgccgagaac aaagtgttta gtgaaatagg taatttgaag
     6901 catttgaaaa aagaacgacc tgatatttta atcggtgttt gtggttgtat gtcacaagaa
     6961 gagtcagtag tgaataaaat tttaaaatcg tatcaaaatg tagatatgat atttggtaca
     7021 cataatattc atcatttacc agaaatttta gaagaagcat acttatctaa agcaatggtt
     7081 gttgaagtat ggtctaaaga aggagacgtt attgaaaatc ttccaaaagt ccgtgaaggc
     7141 aacattaaag catgggtcaa tattatgtat ggttgtgata agttttgtac atattgtatt
     7201 gttccattta caagaggtaa agaacgaagc cgtagacctg aagacattat agatgaagta
     7261 cgtgaacttg ctcgtgaagg ttacaaagaa ataacgcttt taggtcaaaa tgtaaattct
     7321 tatggtaaag atttacagga tatagaatat gacttaggag atcttttaca agcaatttct
     7381 aaaatagcga ttccaagagt tcgtttcaca acaagtcatc cttgggactt tacagatcac
     7441 atgattgatg ttatttcaga gggtggtaat atcgttcctc atatccactt gccagttcaa
     7501 tctggaaata atgcagtatt aaaaataatg ggtagaaaat atacacgaga aagttatttg
     7561 gatttagtaa aacgaatcaa agatagaatt cctaatgtag cattaactac agatattatt
     7621 gtagggtatc caaatgaatc agaggaacaa tttgaagaaa ctttaactct gtatgatgaa
     7681 gttggttttg aacatgcata tacgtacttg tattcacaac gtgatggtac gcctgctgct
     7741 aaaatgaaag ataatgtacc tttaaatgtc aaaaaggaac gattgcaacg tttgaataaa
     7801 aaagttggtc attattcaca aatagctatg agtaagtacg aaggacaaac tgtaacagta
     7861 ctttgtgaag gtagtagtaa aaaagatgat caggttcttg ctggctacac tgataaaaat
     7921 aagctagtta atttcaaagc acctaaagaa atgattggta aactagtgga agtacgaata
     7981 gatgaagcta aacagtattc attaaatggc agttttgtaa aggaagtaga gccggaaatg
     8041 gtgattcaat aaatgtataa taaagatgac gtgttgaaac aagcggataa tattgcaaat
     8101 aaaattaaaa atttggatac tatcaaaaca tatcaacaaa ttgaagcaca gattcatcag
     8161 aaccaaacga taaagactaa aatggatatg ttaaaaaagc atcaaaaaca agcagtaaac
     8221 tttcaaaatt acgggaaaca aaatgcgcta gaacagtcgg aacataccat tcaaagtata
     8281 gaagcagaaa taaatacatt gcccatagtt gaacagtttc aaacttcaca atatgaagcg
     8341 aatcaattat tgaaaatgtt tgtatcaaca atggaaacac gtttaaatga ccataataaa
     8401 gccaagcata gtgattaatt acaaacaaaa aggagaacaa tcatatgaaa tcaagaaaac
     8461 tggctataac tgcactttta attgcaataa atgttgtatt aagcagtatt atcatcattc
     8521 ctctaggacc agttaaggca gcaccagtac agcattttgt aaatgtatta agtgcggtca
     8581 tagtaggtcc ttggtatgga ttagctcaag cgcttatatc atcaatttta agagttcttt
     8641 ttggtactgg tacagctttt gcatttccag gtagtatgat tggagtttta ttggctagta
     8701 tgttttacat atatcgtaaa catatattca tggccgcggt cggtgaagta cttggaactg
     8761 gtgtcatcgg aagtttaatt tgtataccat tagcatattt ccttgggctt caagacttct
     8821 tcattaaacc gctaatgatt acgttcatag tctcaagtgc tatcggatct attataagtt
     8881 atttcttatt aattactcta aaaaaacgtg gtattcttca aaggtttata aaataatttt
     8941 atgatatatg atttcaaaca gagtcattgt tcattttaat attgaacgcc cttacttaat
     9001 taaatgtctt gaatgttaga attttaattt aattctaaac atgctattga cacattttat
     9061 taggtttgag gcgttttctt atacatttaa gatgcttcgt gattatatgg tatgaatagg
     9121 tttgtaaaag taagtatgtt aaaatgtata agttaaataa ttaataatta gaaagcttac
     9181 aaacgaatat attgtaaaga caaattttaa aaagagacaa gggttgtgaa gaaataatat
     9241 gtctaatgtt acaccaatga tgcagcaata tttaaaaata aaatcagaat accaagattg
     9301 cttattattt tttagactag gtgatttcta tgaaatgttt tatgaagatg ccaaggaggc
     9361 atcacgtgta cttgaaatta ctttaactaa aagagatgct aaaaaagaaa atccaattcc
     9421 gatgtgtggt gttccgtatc attctgcaga tagttatata gatacacttg ttaataatgg
     9481 atataaagta gctatttgtg aacagatgga agatccgaaa caaacgaaag gtatggttag
     9541 acgtgaggta gtaagaattg tgactccagg aactgtgatg gagcaaggtg gtgtagatga
     9601 taaacaaaat aactatattt taagttttgt tatgaatcaa cctgaaattg cgcttagtta
     9661 ctgtgatgtt tctactggcg aattaaaggt tacacatttt aatgatgaag cgactttatt
     9721 aaatgaaatt acgacgataa accctaacga agttgttatc aatgacaata tttccgataa
     9781 tttaaaaaga caaattaata tggtgacaga aacaataaca gtcagggaaa cgttatcatc
     9841 agaaatctat agtgtgaatc aaactgaaca taaattaatg tatcaagcga cacaattatt
     9901 gctagattat attcatcata cacaaaaacg tgatttatcg catatcgagg atgttgttca
     9961 atatgcagct atagattata tgaaaatgga tttttatgct aagagaaacc ttgagttaac
    10021 ggaaagcatt cgattaaaat caaaaaaagg aacgctactt tggctaatgg acgaaacgaa
    10081 aacaccaatg ggagcacgcc gcttaaaaca atggatagat agaccactaa taagtaaaga
    10141 acaaattgaa gcacgattag atatcgttga tgaatttagt gctcatttca tagaaagaga
    10201 caccttaaga acatatctta atcaagtgta tgatattgaa cgtcttgttg ggcgtgttag
    10261 ttacggaaat gttaatgcga gagatttaat tcaacttaaa cattccattt ctgaaatacc
    10321 gaatattaaa gcattactaa attctatgaa tcagaatacg cttgtacaag ttaatcaact
    10381 agaacccctt gatgatttac ttgatatatt agaacagagt ttagtagaag aaccaccaat
    10441 ttcagttaaa gatggcggac tattcaaagt tggttttaat acgcaattag atgaatatct
    10501 tgaagcttca aaaaacggaa aaacatggtt agcagaatta caagccaaag aaagacaacg
    10561 tacaggaata aaatcattga aaataagctt taataaagtg tttggttatt ttatagaaat
    10621 aacacgtgcc aacttgcaaa attttgaacc aagtgaattt ggttatatga ggaagcaaac
    10681 gttatcgaat gctgaacgtt ttataactga tgaacttaaa gaaaaagaag atatcatttt
    10741 aggtgcggaa gacaaagcca tcgaattaga atatcaatta tttgttcagc tacgtgaaga
    10801 agttaaaaaa tatactgaac gtttacaaca acaagctaaa attatttcag agctagattg
    10861 tttacagagc tttgcagaaa ttgctcaaaa atataattac actaggcctt catttagtga
    10921 aaataaaaca ttagaattag tggaatctag gcacccagta gtggaaagag taatggatta
    10981 taatgactat gtgcctaata attgtcgatt agataatgaa acatttatat atttaattac
    11041 aggtccgaat atgtctggta aatcgacata tatgagacaa gttgccataa ttagtataat
    11101 ggcccaaatg ggagcttatg tcccttgtaa agaggcagtg ttacctatat ttgatcaaat
    11161 attcactaga ataggtgcgg cagatgattt ggtttcaggt aagagtacgt ttatggtaga
    11221 aatgctagaa gcacaaaagg cattaactta tgcaacagag gatagtttga ttattttcga
    11281 tgaaattgga cgtggtactt caacgtatga cggtttagct ttagcgcagg caatgataga
    11341 gtatgtagct gaaacatcgc atgctaaaac gttattttca acacattatc atgaattgac
    11401 aacattagat caagcattac caagtctaaa aaatgttcac gtcgctgcta atgaatataa
    11461 aggtgaactt atattcttgc ataaagtcaa agatggtgca gttgacgata gttatggtat
    11521 tcaagttgcg aaattagctg atttacctga aaaagttatt agcagagcac aagtgatcct
    11581 aagcgagttt gaagcgtctg ctggtaaaaa atcatcgata tcaaatttaa aaatggtcga
    11641 aaatgaacct gaaattaatc aagaaaattt aaacttaagt gttgaagaaa caactgatac
    11701 tttatctcaa aaagactttg aacaagcatc atttgatttg tttgaaaatg atcaagaaag
    11761 cgagattgaa ctacaaatta aaaatttgaa tttatctaat atgacaccaa ttgaggcatt
    11821 ggtgaagtta agtgaattac aaaatcaatt aaaatagagg tgttgcaaaa tggggaaaat
    11881 taaagaactc caaacctcat tagcaaataa aatcgcagca ggtgaagtag ttgaaagacc
    11941 gagttctgtt gtgaaagaac tgttggaaaa tgctatagat gcaggcgcta cagaaataag
    12001 cattgaagta gaggaatctg gcgtccaatc tattcgcgta gtcgataatg gaagcggaat
    12061 tgaagcggaa gacttaggat tagtatttca tagacatgcg actagtaaat tagatcaaga
    12121 tgaagattta tttcatatta ggacattagg attccgtggt gaagcactag ccagtatttc
    12181 atcagttgct aaagtaacat tgaagacttg cacggataat gctaatggaa atgaaatata
    12241 tgtagaaaat ggtgaaatat taaatcataa gcctgcaaaa gcgaaaaaag gaacagatat
    12301 acttgtagaa tcattatttt ataatacacc agcacgttta aaatatatta aaagtttata
    12361 cactgaacta ggtaaaataa cagatattgt caatagaatg gctatgagcc atccggacat
    12421 tcgaatagca ctcatttcag atggcaaaac aatgttaagt acaaatggtt caggacgaac
    12481 taatgaagtg atggcagaga tttatgggat gaaagttgca cgagatttag tacatatatc
    12541 tggagataca agtgattatc acattgaagg ttttgttgca aagcctgaac attctagaag
    12601 taataagcac tatatttcta tttttattaa tggacgatac attaaaaact ttatgctaaa
    12661 taaagcgatt ttagaaggct atcatacact cttaacaata ggtaggttcc cgatttgtta
    12721 tattaatatt gaaatggatc caatcttagt agacgtaaat gttcatccaa caaaactaga
    12781 agtgcgttta tcaaaagaag agcaactata tcaattgata gtgagcaaaa tacaagaagc
    12841 atttaaagac cgtatattaa ttcctaaaaa taacttggat tatgtgccaa aaaaaaataa
    12901 agtattatat tcattcgaac aacaaaaaat cgaatttgaa caaagacaaa acacagagaa
    12961 taaccaagag aagacgtttt catctgaaga aagtaacagt aagtcattta tggcagaaaa
    13021 tcaaaacgat gagatagtta taaaagaaga ttcatataat ccattcgtaa cgaaaacatc
    13081 tgaaagttta ataactgatg atgaatcttc tggttataat aatacacgtg aaaaagatga
    13141 agactacttc aaaaaacaac aagaaatttt acaagaaatg gatcaaacat ttgattcaaa
    13201 tgaggatgca tctgtgcaaa attatgagaa taaagcgtct gatgattatt atgatgtaaa
    13261 cgatattaaa ggaacaaaaa gtaaagaccc taaacgaaga attccatata tggaaattgt
    13321 tggccaagta catgggacgt atattattgc tcaaaatgaa tttggcatgt acatgattga
    13381 ccagcatgca gctcaagaaa gaataaaata tgaatatttt cgagataaaa taggtgaagt
    13441 taccaatgaa gtacaagatt tattaatccc gttaacattt catttttcaa aggatgaaca
    13501 attagttatt gatcaatata aaaatgagct tcaacaagta ggtatcatgt tagaacattt
    13561 tggtggtcat gattatattg taagtagcta tccagtttgg ttccctaaag atgaagtaga
    13621 agaaatcatt aaagatatga ttgagctaat tttggaagag aaaaaagtag atattaaaaa
    13681 attacgtgaa gatgtagcaa tcatgatgtc atgtaaaaaa tctattaaag cgaatcatta
    13741 tttacaaaaa catgaaatgt ctgatttaat tgatcaatta agagaagcgg aagatccatt
    13801 tacatgtcca catggtcgtc caataatcat taatttttca aaatacgaat tagaaaaatt
    13861 atttaagcgt gtgatgtaga gaggatgaat caagtgaata acaacatatt gcctgctata
    13921 agaaacatta aagatttaga gaaactgatt aaaacagatt ataaaatgtg tgtgcttcta
    13981 gatatgcata taggacatat aaaaagtatt atggaattgc tgaagcaaaa tcatatagag
    14041 tgttttattc atatagattt gataaaaggt ttaagccacg atgaatttgc aagtgaattt
    14101 attattc
//
LOCUS       DAPDIM010000067        13722 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000067 DAPDIM010000000
VERSION     DAPDIM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13722
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.067"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            25..741
                     /locus_tag="RFE25_002247"
     CDS             25..741
                     /locus_tag="RFE25_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817283.1"
                     /translation="MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKD
                     QDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMS
                     LFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIP
                     ITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIW
                     ILLVVLVIYFTIRLSSRTRL"
     gene            910..1698
                     /locus_tag="RFE25_002248"
     CDS             910..1698
                     /locus_tag="RFE25_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2817284.1"
                     /translation="MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLA
                     SSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLF
                     TDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEK
                     TMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDK
                     NHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLNFLKSVS"
     gene            complement(1950..2324)
                     /locus_tag="RFE25_002249"
     CDS             complement(1950..2324)
                     /locus_tag="RFE25_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SarA family transcriptional regulator"
                     /protein_id="HDU2817285.1"
                     /translation="MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYIS
                     ENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRK
                     KIESLLSRVNKRITEANNEIEL"
     gene            complement(3272..4201)
                     /locus_tag="RFE25_002250"
     CDS             complement(3272..4201)
                     /locus_tag="RFE25_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDU2817286.1"
                     /translation="MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGT
                     ICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIA
                     TVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKY
                     LLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSITLLILTAIFNSSL
                     KLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILID
                     HFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF"
     gene            complement(4396..4620)
                     /locus_tag="RFE25_002251"
     CDS             complement(4396..4620)
                     /locus_tag="RFE25_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499185.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDU2817287.1"
                     /translation="MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLN
                     IIKSNSGTITKVHSAQIIDKTTTVLFEDKK"
     gene            complement(4637..4840)
                     /locus_tag="RFE25_002252"
     CDS             complement(4637..4840)
                     /locus_tag="RFE25_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817288.1"
                     /translation="MSKINHITIVLSFTKVDANGKQTEFKRRFANINPDASNDQIKTF
                     SKLIERLTGETYNNIELIKSLSI"
     gene            4999..5559
                     /locus_tag="RFE25_002253"
     CDS             4999..5559
                     /locus_tag="RFE25_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDU2817289.1"
                     /translation="MNKVEAIKFNDDIVKMYEALKIKSERDYLFFKLAIHSGLKVSEL
                     LTITVSQVKRLIEKCTLSEMCKAHFHSLIKIRLPETLSKELLQYIEDRSLSNEDVLFQ
                     SLRTNQVLSRQQAYRIIHQASIEAGIDNVGLTTLRKTFAYHAYQKGIPIPVIQKYLGH
                     QSAIETLNFIGLENECEHSIYISLQL"
     gene            5578..7875
                     /gene="mnhA2"
                     /locus_tag="RFE25_002254"
     CDS             5578..7875
                     /gene="mnhA2"
                     /locus_tag="RFE25_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit A"
                     /protein_id="HDU2817290.1"
                     /translation="MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALVAPVISSIY
                     FLIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLTLFMFSMIGIVLSDNTILMYI
                     FWELTSVSSFLLISYWYNNGDSQFGAIQSFMITVFGGLALLVGFIMLYIMTGTNNITD
                     ILGQADHIKNHGLFIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMV
                     KAGIFLLLRFTPLLGLSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLG
                     MIMAMVGIGGGYAQHQQDAIASIYVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGS
                     RDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLI
                     SMIAIVFVGVIASIFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVL
                     VPVIFFVPNIFGKGIIVPALRGVSGGNHQIDPLAPHVSQWHGFNIPLLLTIIIILLGS
                     VLAIKVDWKKVFTGKIRQISVSKGYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGI
                     FMIIIGYGYIRIGLPKVHQLHVSEFGALEIILAIVTVTIGISLIFIRQRLTMVILNGV
                     IGFVVTLFFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISV
                     SLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGL
                     VLIITGLGIYTLLNYQDRRGQDERE"
     gene            7862..8287
                     /gene="mnhB2"
                     /locus_tag="RFE25_002255"
     CDS             7862..8287
                     /gene="mnhB2"
                     /locus_tag="RFE25_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit B"
                     /protein_id="HDU2817291.1"
                     /translation="MKENDVVLRTVTKLVVFILLTFGFYVFFAGHNNPGGGFIGGLIF
                     SSAFILMFLAFNVEEVLESLPIDFRILMIIGALVSSITAIIPMFFGKPFLSQYETTWI
                     LPILGQIHVSTITLFELGILFSVVGVIVTVMLSLSGGRS"
     gene            8284..8628
                     /gene="mnhC2"
                     /locus_tag="RFE25_002256"
     CDS             8284..8628
                     /gene="mnhC2"
                     /locus_tag="RFE25_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit C"
                     /protein_id="HDU2817292.1"
                     /translation="MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIM
                     SMGTYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKED
                     EIEGLRGEDDAK"
     gene            8618..10114
                     /gene="mnhD2"
                     /locus_tag="RFE25_002257"
     CDS             8618..10114
                     /gene="mnhD2"
                     /locus_tag="RFE25_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit D"
                     /protein_id="HDU2817293.1"
                     /translation="MLSNLLILPMLLPFLCALILVFLKNNDRISKYLYLGTMTITTII
                     SLMLLIYVQRHRPITLDFGGWSAPFGIQFLGDSLSLIMVTTASFVITLIMAYGFGRGE
                     HKANRYHLPSFILFLSVGVIGSFLTSDLFNLYVMFEIMLLASFVLITLGQSVEQLRAA
                     IIYVVLNIIGSWLFLLGIGLLYKTVGTLNFSHIAMRLNDMGDNRTVTMISLIFLVAFS
                     AKAALVLFMWLPKAYAVLNTELAALFAALMTKVGAYALIRFFTLLFDQHNDLIHPLLA
                     TMAAITMVIGAIGVIAYKDIKKIAAYQVIISIGFIILGLGTNTFAGINGAIFYLVNDI
                     VVKTLLFFIIGSLVYITGYRQYQYLNGLAKKEPLFGVAFIIMIFAIGGVPPFSGFPGK
                     VLIFQGALQNGNYIGLALMIITSLIAMYSLFRILFYMYFGDKDGEEVNFKKIPLYRKR
                     ILSILVVVVIAIGIAAPVVLNVTSDATELNTSDQLYQKLVNPHLKGED"
     gene            10115..10597
                     /gene="mnhE2"
                     /locus_tag="RFE25_002258"
     CDS             10115..10597
                     /gene="mnhE2"
                     /locus_tag="RFE25_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit E"
                     /protein_id="HDU2817294.1"
                     /translation="MNQIVLNIIIAFLWVLFQDEDHFKFSTFFSGYLIGLIVIYILHR
                     FFSDDFYVRKIWVAIKFLGVYLYQLITSSISTINYILFKTKDMNPGLLSYETRLTSDW
                     AITFLTILIIITPGSTVIRISQDSKKFFIHSIDVSEKEKDSLLRSIKHYEDLILEVSR
                     "
     gene            10594..10896
                     /gene="mnhF2"
                     /locus_tag="RFE25_002259"
     CDS             10594..10896
                     /gene="mnhF2"
                     /locus_tag="RFE25_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit F"
                     /protein_id="HDU2817295.1"
                     /translation="MIQTITHIMIISSLIIFGIALIICLFRLIKGPTTADRVVTFDTT
                     SAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSVSISRFIGGGHVFNGNNKRNL"
     gene            10871..11308
                     /gene="mnhG2"
                     /locus_tag="RFE25_002260"
     CDS             10871..11308
                     /gene="mnhG2"
                     /locus_tag="RFE25_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit G"
                     /protein_id="HDU2817296.1"
                     /translation="MEITKEIFSLIAAVMLLLGSFIALISAIGIVKFQDVFLRSHAAT
                     KSSTLSVLLTLIGVLIYFIVNTGFFSVRLLLSLVFINLTSPVGMHLVARAAYRNGAYM
                     YRKNDAHTHASILLSSNEQNSTEALQLRAKKREEHRKKWYQND"
     gene            11648..13690
                     /locus_tag="RFE25_002261"
     CDS             11648..13690
                     /locus_tag="RFE25_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDU2817297.1"
                     /translation="MEIFETILIFIAVVILSSFVHTFIPKVPLAFIQIFLGMLLFITP
                     IPVQFNFDSELFMVTMIAPLLFVEGVNVSRVHLRKYIKPVMMMALGLVITTVIGVGLF
                     IHWIWPDLPIGAAFAIAAILCPTDAVAVQAITKGKVLPKGAMTILEGESLLNDAAGII
                     SFKIAVGVLVTGAFSLVDAVQLFLIASIGGAVVGLLIGMALVRFRLTLMRRGYENINM
                     FTIIQLLTPFVTYLIAELFHASGIIAAVVAGLVHGFERDRIMQVRTQLQMSYNHTWNI
                     LGYVLNGFVFSILGFLVPEVIIKIIKTEPHNLIFLIGITIVVALAVYLFRFVWVYVLY
                     PYFYLANSPFQKMMTKNDDDNPTTEKPPKRSLYALIMTLCGVHGTISLAIALTLPYFL
                     AGHHAFTYRNDLLFIASGMVIISLVVAQVLLPLLTKPAPKTVIGNMSFKVARIYILEQ
                     VIDYLNQKSTFETSFKYGNVIKEYHDKLAFLKTVEKDDENSKELERLQKIAFNVETKT
                     LESLVDEGQITNSVLENYMRYAERTQVYRQASLIRRMIVLLRGALLKRRVQTRVNSAS
                     SLSVTDNLMELNKINKLVHYNVVSRLSKETTKDNTLEIGMVCDGYLMRIENLTPSNFF
                     NSASEDTITKIKLNALREQRRILRELIDTDEVSEGTALKLREAINYDEMVIVDSMT"
BASE COUNT         4618 a         1853 c         2295 g         4956 t
ORIGIN      
        1 tttcatttta aaggagtact accaatgcgt attaacgata aaattttact agaaaatata
       61 gaagattact ttaatcataa aggtttatca ccgcatttga ttgatgatat taaagagaaa
      121 gtaattactg atataaaaaa ttctgaaaag aaagatcaag attatattga atataaaaga
      181 aaatctccag cacaaatcat attaatgatt caaaggaatt tatttgcttt acaaatgaat
      241 ccagttattt tctttattat aaacttcatt ctcatatcct atttatatga taaacagtat
      301 gttcagtttc aagctattac tggaatgagt ctattttatt gtttagtgat ttttccaatg
      361 actattgttg tatacctaag ggtgtcacaa aagaattact tgcgtagtaa taaaatagaa
      421 atgattatgg gtacaattat cgctatcata tccttgttat taattatatt acaagcattt
      481 aatattactt ggggcgttat accaattaca aattttggac atcaattttt ctttttcatt
      541 ggtattattt tagtaattgc cggcatattt tataagcgac ttgagttttc gggaatcggc
      601 ttattatttt gtcaaaaaac cgtcgatgca atgattcata atccacaatc agcccagatt
      661 ttttcattaa ttatatggat attattagta gttctagtta tatatttcac aattagatta
      721 tcttcacgta caagattata aatatgataa aactattcac ttgattaatt gtattaattg
      781 agatgaatag tttttttatt gttggaataa cttttggtaa tttataaata atttaaaaaa
      841 attgtttata aaatggaagc gtatatagaa tgaaggttgg gtatatagtt tattgaggga
      901 ggtgtcacaa tgaataaagt cacaattaat cctcaaatcc aattaactta tcaaattgaa
      961 ggtaaagggg atcctataat attacttcat ggattggatg gtaatttagc tggatttgaa
     1021 gatttgcaac atcaactagc atcatcatat aaagtactta cttacgattt aagaggtcat
     1081 ggcaagtctt ctaaaagtga atcatacgat ttaaacgatc acgttgagga tttaaaaatt
     1141 ctaatggaga agttaaatat tcatgaggca catattctag gacatgattt aggtggggta
     1201 gttgctaagt tatttacaga taaatatgct tatcgtgtaa aatcattaac taccattgca
     1261 tcgaagaaag atgacttaat acacagcttt actcaattgt taatacaata tcaagatgat
     1321 atagcgggtt ttaataagtc tgaagcgtat attcttttat tttctaaatt gtttagaaat
     1381 caagagaaga cgatgaaatg gtatcaaaaa caaagaatat atagcattaa gtctgaggat
     1441 gatagtgcgg tggcaattcg ttcattaatt ttgcataaag atgaacctat gtatttaaaa
     1501 aaacgtacat gtgtacctac tttgttaatt aatggggaac atgatccttt gattaaagat
     1561 aagaatcatt ttaaattgga agcgcatttt ttaaatgtta cgaaaaaaat cttcgaacat
     1621 tcaggacatg caccgcatat tgaagaacca gaagcattta tgaattatta tttaaatttt
     1681 ttaaaaagcg tatcataata tgtgatatat aaacctaggg cataaagtcc ttaggcaatg
     1741 tgaaaaagct gattactatt cattatttga tagaaatcag ctttttttga aatgtatttg
     1801 atatatactg ctcgttatgc ggctatcttc cttatattaa gtgccattag tgcaaaacct
     1861 cttaacaatt aggtaaaaaa agacataaaa aaaggaagtt taatagaatg tatcatctat
     1921 caaacttcac caaattgcgc taaacaaaat tatagttcaa tttcgttgtt tgcttcagtg
     1981 attcgtttat ttactcgact caataatgat tcgatttttt tacgttgttg tgcattaaca
     2041 agaattaata cagttctttc atcatgctca ttacgttttt tatcgaagta atcttcttga
     2101 gataaaattt taactgcttt aacaacttgt ggttgtttgt agtttaaatg attaataata
     2161 tctttaagat agtattcttt ctctttgttt tcgctgatgt atgtcaatac agcgaattct
     2221 tcaaagctaa ttgaaaattc ctttttaatt aaacttttta atttgtcagc ataagtgacc
     2281 attgataaca actcaaagca atcattgatt tttgtaattg ccatgtttaa aacctcccta
     2341 tttgatgcat cttgctcgat acatttgccc gataatatat tgatatctaa tctttattta
     2401 ttatagatat gttagtcata attttgcatt aaataagttt tattaaatat atttaatgct
     2461 ctattattta gttaattata actaattaaa aatgagaagt aaacaaaaaa gtgtttataa
     2521 aacaaattat tcattagaca cagtgattgt atttctgggt tagcatttgg tttagtcaaa
     2581 aatatcagca ttttttataa tttaccttaa tttaatcgcc aatacaaggt aatttattta
     2641 atgaaacgat ttagcgcaat taaatgtttc gatattcaat gtgtgtctaa agagattctt
     2701 tgttatagct taactcttcc aagttaactt cttctactat ttatacccat ttttcagaat
     2761 tttatcacta aaaatgaaaa atttttataa tttttttaat ttagtaattc tcagtgcagt
     2821 tttaatgata agaaaaacac attaatttag tgattaaaac caatctatag cacgttaaag
     2881 tgtatatacg ttattccgat tgataacggg taacaaataa tagaaagtac gataattgat
     2941 catgcattaa agcactttta tttttcaaac tcgactcaat gaattataaa aagttgtgca
     3001 ttttgactta tttttaatta attgaataac caactatgaa atattagcac gaataacata
     3061 atttttgcta ttaatttggt gtaaattatt aaaaaataac attaatttag gtcttaagaa
     3121 tgagttgact atcgaatttg ctaaattaaa atttgttgtg tcaaagtata ctacccaaat
     3181 caacgctttt ctaaagattt ttagaccaca aaaaaatagc ttatcacttt taaaaataat
     3241 tacaagttaa aatgataagc taaaagttaa tttaaaataa tcttaaaagt ataatgcctg
     3301 tcaaaataca taatagacca atagtttttc tggatgtcat tgctatttta ggtgaaccaa
     3361 ataatccaaa gtgatctatc aatatgccca ttagaatctg gccaaacatc ccaataagtg
     3421 ttgttaatgc tgcacccata tgaggcatta agataatgtt agctgttaca aaagccatac
     3481 caagtatacc gccagtaaaa tagataggct ttaatttacc gaattttaaa tgacttgttt
     3541 ttagttttaa agaactatta aaaatagcgg ttaaaatcaa tagcgttatt gacccaattg
     3601 taaatgatac taatgatgca aaggctggtg aatgagtatg acttgctaaa gcactattaa
     3661 ttgtcgtttg aataggtgga aagaaaccaa aaataaatcc taagagaagc caaaacagta
     3721 aatacttttg atcagttagt aataaattat tcttgttaaa ttgattcatt atgacgatgc
     3781 cgacaatgag taacaatact ccaattgctt taattaaatt aaaatcatga attgtagcgc
     3841 caaataagcc aaatgtatca ataatgacac ccataataat ttgacccgca actgttgcaa
     3901 ttacagttaa tgttgcacct aattttggca ataacaataa attgccagtt aaaaagctaa
     3961 ccccaagcaa accaccgact acccatgtgt agttaaatga ttgattattg taaaagtgaa
     4021 tagtaaatac ttctggattg ataatgatat ttaaaataat taaacaaatt gttccaactg
     4081 aaaatgaaat gaatgaagta tagaaaggcg atttagtata cagtgatagt cttgaattga
     4141 cagatgtttg gataggaata agcattccaa ctaggacacc aatgatatag aaaagaagca
     4201 tatgaataaa gtctcacttt ccaaagttaa taataaaatc atatgaatac attatcatta
     4261 tagagaaaat atacaactca tttacaataa tgttgaaaaa aacaggacat tatcataaca
     4321 aaatcaccct agacaatcat gatgaaagtc tagggtgtta gtatttatac taaattaatt
     4381 gcgctttctt tatatctatt tcttatcttc aaataaaaca gttgttgttt tatcaataat
     4441 ttgagcagaa tgtactttgg tgatagtacc actatttgac tttataatat ttaaatctac
     4501 taatgcattc atactatcac gtgcaacttg ctcggtcact acgttgttta attgtggtaa
     4561 ttgcagtttt acaggcttgt ctagtgaaga tttaaaactt aattcaagtg ttttagtcat
     4621 gaatatgtcc tcctgattaa attgataaag atttgatgag ttcgatattg ttatatgttt
     4681 ctccagtaag tcgctcaata agtttgctga atgttttaat ttggtcgttt gatgcatcag
     4741 ggttaatgtt agcgaatcga cgcttaaatt ctgtttgttt gccgttagcg tctactttag
     4801 taaatgataa tacaatagtg atgtggttta ttttactcat attttaaaac ctcctttcac
     4861 actatatatc gaaataaaat aataaaatgg ctaattttat tttctatgtt taaaatctat
     4921 aaaaaaggca atagatatat gtaactaaaa tataaaatag ctatgattaa gacacttaaa
     4981 gcaaggggag gttgagtaat gaataaagta gaagcgatta aatttaatga tgatattgtt
     5041 aaaatgtatg aagcgctcaa gataaaatct gaacgtgact atttattctt taagttagct
     5101 atacatagtg gattgaaagt atcagaatta ttaacaatta cagtctctca agttaagaga
     5161 ctaattgaaa agtgtacgtt atcagaaatg tgtaaagcac attttcattc gttgattaaa
     5221 attaggttac cagaaacatt atcgaaagaa ctacttcaat atatagagga caggagtctt
     5281 tcgaatgaag acgttctttt tcaatcacta cgaacaaatc aagtattatc tagacagcaa
     5341 gcatatcgaa taattcacca agcatcaatt gaagctggta tagataatgt aggactaacg
     5401 acattgcgta agacatttgc atatcatgct tatcaaaaag gtatacctat accagtcatt
     5461 caaaagtatt tagggcatca atctgctatt gaaacactaa attttatcgg tttagaaaat
     5521 gagtgtgaac atagtattta tatttcatta caattataga aacaaaggag gctaataatg
     5581 agtttggttt atttattaat tgctatactt gtgattatgg cgatgatact tctaatgtct
     5641 aaacgtagag cattggctaa atatgccggg tacatagcgt tggttgcacc tgtaatttca
     5701 tctatctatt ttttgattca aataccatca gtagctaaac tgcaatatct ttctacctct
     5761 attccatgga ttaagacatt agatattaat ttagatttac gtttagatgg tttaagttta
     5821 acgttattta tgttcagtat gattggtatt gtattatcag acaatacgat attgatgtac
     5881 attttttggg aattaacgag tgtatcatca tttttattga tttcatattg gtataacaat
     5941 ggtgacagtc aatttggtgc gattcaatca tttatgatta cagtatttgg tggattggcg
     6001 ttattagttg gttttattat gctgtatatc atgacaggaa cgaataatat cactgacata
     6061 ttaggacaag cagatcatat taagaatcat ggattgttta tccctatgat ttttatgttt
     6121 ttattaggtg catttacaaa atcagcacaa tttccatttc atatttggct acctagagca
     6181 atggctgcac ctacacctgt aagtgcttat ttacattcag ccacgatggt aaaagctggt
     6241 atctttttat tacttcgatt tacaccatta ttaggtctta gcaatatgta catatatatc
     6301 gtcacgtttg ttggtttaat aacaatgtta tttggttcaa tcacagcttt aaaacaatgg
     6361 gatttaaaag gaatcctagc atattcaaca atcagtcaac taggaatgat tatggcaatg
     6421 gtcggtatcg gtggtggata tgctcaacac caacaagacg caatagcatc tatttatgta
     6481 tttgtattat ttggtgcgct atttcatcta atgaatcatg ccatctttaa atgtgcgctt
     6541 ttcatgggag taggtatttt agatcatgaa gcaggttcaa gggatatacg aattttaagt
     6601 ggaatgcgtc aactatttcc taaaatgaat ctagtcatga cgatagcggc tctatctatg
     6661 gctggagtac catttttaaa tggattttta agtaaagaaa tgtttttaga tgcattaaca
     6721 caaactggac aattatccca atttagtttg atttcaatga tagctatcgt gtttgttggt
     6781 gttattgcta gtatttttac attcacatat gcactttaca tggttaaaga agtattttgg
     6841 actaaatatg attctaaagt gtttactaaa aaaaatatcc acgaaccatg gttgtttagt
     6901 ttaccctctc ttatattaat ggtgctagta cctgtaatct tttttgtgcc aaatatattt
     6961 gggaagggga ttatcgttcc agcattaaga ggtgtatcag gtggtaatca tcaaattgat
     7021 ccattggcac cacatgtttc gcaatggcat ggatttaaca taccgcttct tttaaccatc
     7081 atcattattt tattgggtag tgtactagca atcaaagtag attggaaaaa agtgttcaca
     7141 ggtaaaatta gacagatttc agtttcaaaa gggtatgaga tggtatatcg acattttgaa
     7201 aagtttgcta cgaagcgatt taaacgtgtt atgcaagatc gtttaaacca atacattatt
     7261 atgaccttag gcatatttat gattatcatt ggatatggtt atattcgaat tggacttcct
     7321 aaagtacatc agttacatgt ttctgaattt ggggcattag aaattatatt agcaatcgta
     7381 actgtcacaa ttggtatttc tttaattttt atacgtcaac gactgacaat ggtcatttta
     7441 aatggagtca tcggatttgt tgtgacctta ttctttatag caatgaaagc ccctgattta
     7501 gcattgactc agctagtagt tgaaacaata acgacgatac tatttattgt cagtttttca
     7561 agattaccaa acgtaccaag atctaacgct aacaaaaaaa gagaaataat taaaatttct
     7621 gtatcactct tgatggcact tattgttgta tcattaattt ttattacaca acaaacagat
     7681 ggtttatcat caatatcaga cttttattta aaagctgaca aactaacagg tggtaaaaat
     7741 attgtaaatg cgatacttgg tgactttaga gcattagata cattatttga aggattagtg
     7801 ttaattatta ctgggctagg tatttacaca ttattaaatt atcaagatcg gaggggacaa
     7861 gatgaaagag aatgatgtcg tgttaagaac ggtcacgaaa cttgttgtat ttattttatt
     7921 gactttcgga ttctatgtct tcttcgcagg tcataataat cctggtggtg gctttattgg
     7981 tggtttaata tttagttcag cgtttatttt aatgtttctg gcttttaatg ttgaagaggt
     8041 tttagaaagt ttaccgattg attttagaat tttaatgatt attggagcat tggtatcatc
     8101 tattactgcg ataataccta tgttttttgg aaaaccattt ttgtctcaat atgaaacaac
     8161 ttggatactt ccaattttag ggcaaattca tgtaagtaca ataacacttt ttgaattagg
     8221 tattttattc tcagttgttg gtgttattgt cacagtgatg ttgtcgctta gcggaggtcg
     8281 atcatgaatt taatattatt actagttata ggatttttag tgtttatagg aacatatatg
     8341 attttatcaa tcaatttaat tcgtattgta atcggaattt caatatatac tcatgctggt
     8401 aatctcatta ttatgagtat gggaacgtat ggttctagta gatcagaacc attaataact
     8461 ggtggaaacc aattgtttgt tgatcccttg ttacaagcta ttgtactaac tgcaatagtt
     8521 atagggtttg ggatgactgc gtttttactt gtacttgttt atagaactta taaagtaaca
     8581 aaagaagatg aaattgaagg cctaaggggg gaagatgatg ctaagtaact tattgatttt
     8641 accaatgtta ttaccattcc tttgtgcctt aatccttgta tttttaaaaa ataatgatcg
     8701 tatttctaaa tatttatact taggtacaat gactatcacc acaattattt cattaatgct
     8761 attaatttat gttcagcgtc accgtccaat tacgctagac tttggaggat ggtcagcgcc
     8821 ctttggtata cagtttttag gagattcttt aagtttgatt atggttacaa ccgcttcgtt
     8881 tgtgattact ttaattatgg catacggatt tgggcgtggc gaacataaag caaatcgtta
     8941 tcacttgcca tcgttcatat tatttttaag tgttggcgtg ataggctctt ttctaacatc
     9001 agatttattt aatttatacg tcatgtttga aattatgtta ctagcgtcat ttgtactcat
     9061 tacacttgga caatctgtag aacaattacg tgctgcaatt atttatgttg tcttgaatat
     9121 tattggttca tggctattct tattaggtat aggtttactt tataaaacag taggtacatt
     9181 aaacttttca catattgcaa tgcgtttgaa tgacatggga gataatcgca ctgttacaat
     9241 gatttcatta atcttcttag tcgcatttag tgcgaaagca gcgctggtcc tttttatgtg
     9301 gctacccaaa gcctacgctg tgttaaatac tgagcttgca gcattatttg cagcgttaat
     9361 gaccaaagta ggggcctatg cattaattcg attcttcact ttactatttg atcaacataa
     9421 tgatctcata catccattgc tagcaactat ggctgctata actatggtca tcggcgctat
     9481 aggtgtcatt gcttataaag atattaaaaa gattgcagct taccaagtca taatctcaat
     9541 aggatttatc attttaggtt taggaacaaa cacgtttgca ggtattaatg gtgcaatatt
     9601 ttatttggta aatgacattg ttgtaaaaac attgctattc tttattattg gtagtttagt
     9661 ttacattaca ggctatcgac aatatcaata tttgaatggc ttagctaaaa aagaaccttt
     9721 atttggagtt gcgtttatta taatgatttt tgctattggc ggcgtgcctc catttagtgg
     9781 ctttccgggg aaagtactta ttttccaagg tgcattgcaa aatggcaatt atattggact
     9841 agcgttaatg attattacta gtctaattgc aatgtacagt ttatttagga tactttttta
     9901 tatgtatttt ggagataaag atggggagga agttaatttt aagaaaatcc cgctatatcg
     9961 aaaaagaatt ttaagtattt tagtagttgt ggttatcgca atcggaattg ctgcacctgt
    10021 tgtgttaaat gttacaagtg atgcaactga gttgaacacg agtgatcaat tatatcaaaa
    10081 acttgtaaat ccgcatttga aaggagagga ctaaatgaat caaatagttt taaatattat
    10141 cattgcattc ttatgggtat tatttcaaga tgaagatcat tttaaattct cgactttctt
    10201 ttctggatat ctaattggtt taattgtcat ttatatatta cacaggtttt tcagcgatga
    10261 tttttatgtt agaaaaatat gggtagctat taaattttta ggtgtttatt tatatcaatt
    10321 aataacatct agcattagca cgattaatta tattcttttt aaaacaaaag atatgaaccc
    10381 tggattactt tcatatgaaa caagactaac aagtgattgg gcaataacat ttttaacaat
    10441 tttaattatt ataactccag ggtctacagt aatacgaatt tctcaagact ctaaaaagtt
    10501 ttttattcat agtatcgacg tgtcagaaaa agaaaaagat agtttgttaa gaagtattaa
    10561 gcattatgaa gacttaatat tggaggtgtc gcgatgatac aaacaataac acatattatg
    10621 attattagtt cactcattat ttttggaatt gcattaatca tctgtttatt tagattaatc
    10681 aagggaccta caacagcaga tcgtgtcgtt acatttgata caacaagtgc tgtcgtaatg
    10741 tcaattgtgg gtgtgttaag tgtacttatg ggcaccgttt ctttcttaga ttcaatcatg
    10801 ctcattgcca ttatatcttt tgtaagttct gtttcaatat cacgctttat tggtgggggg
    10861 catgtgttta atggaaataa caaaagaaat ctttagtctt attgctgctg tgatgttgtt
    10921 gttaggtagt tttattgctc ttattagtgc aataggtatc gtgaaattcc aagatgtttt
    10981 cttaagaagt cacgctgcga caaaaagttc aactttatcc gtgttattaa ctttaatcgg
    11041 tgtattaatt tattttattg tgaatacagg atttttcagt gtgcgtttat tactgtcact
    11101 tgtttttatt aatttaactt caccagtcgg catgcactta gtcgctcgcg ctgcttatcg
    11161 caacggcgct tatatgtatc gaaaaaatga tgctcacaca catgcatcaa tattattaag
    11221 ttcaaatgaa caaaactcta cagaagcatt acaattacgt gctaaaaaac gagaagagca
    11281 tcgtaagaaa tggtatcaaa acgattgaag tgttggctaa attgttaagc ataacaatgc
    11341 ttttgaaaat ctgttttcaa aattaatcat taaaagagta ctttgaaatt ggttagtcga
    11401 ttttaaggtg ctcatttttt gtattataag ttaatgttgt tatgtgaaag caagttgttt
    11461 atttatacaa acaattagtg ataaaataaa attaaataat tgcaaattta agtactgcaa
    11521 tcgtagacat atatctatat taaagtgctt ttgtggtcgc taactcaatt tatcctctaa
    11581 agtataatta caacgagatg tgatacttaa ttttcaatta aacaatactt tttagagagg
    11641 tgaaagtttg gaaatatttg aaacaattct tatatttata gctgttgtga tactaagttc
    11701 gtttgtccat actttcatac ctaaagtacc cctagcattt atacaaattt tcttgggcat
    11761 gttactattt attaccccaa tccctgttca atttaatttt gattctgaat tgtttatggt
    11821 aacaatgatt gcgcctttgt tatttgtaga aggtgttaat gtttctagag tccatttaag
    11881 gaaatatatt aagccagtga tgatgatggc attaggatta gtcattacta ctgtgatagg
    11941 tgtaggttta tttattcatt ggatttggcc agatttacct attggagcag catttgcaat
    12001 tgctgccatt ctttgtccta ctgatgcagt agcagtgcaa gcaatcacta aaggaaaggt
    12061 cttgccaaaa ggagcaatga caattcttga aggtgagtca ttattgaatg atgctgctgg
    12121 tattatttca tttaaaatag ctgttggagt attagttaca ggtgcttttt cacttgttga
    12181 tgctgttcag ttgtttttaa ttgcatcaat tggtggcgca gtggttggtt tacttatagg
    12241 tatggcatta gtaaggttcc gattaacatt gatgcgtcga ggatatgaaa acattaatat
    12301 gtttacaatt attcaattgt taacaccatt tgttacgtat ttaattgctg aattgtttca
    12361 cgcatcagga atcattgcag cagtagttgc aggacttgta catggtttcg aacgtgacag
    12421 aattatgcaa gtacgtacac aactgcaaat gagttacaat catacatgga atatactagg
    12481 ttatgtttta aatggctttg ttttttcaat attaggattt ttagtacctg aagttattat
    12541 taaaattatc aaaacagaac cgcacaattt aatcttttta ataggcatca ctattgttgt
    12601 tgctttagct gtctatctat ttagatttgt ttgggtttat gtcttatatc cttattttta
    12661 tttagccaac agtccattcc aaaaaatgat gactaaaaat gatgatgata atccaacgac
    12721 tgagaaacca ccaaagcgaa gtttatacgc tttaattatg acgttatgtg gtgtgcatgg
    12781 aacaatttct ttagcaatcg cattaacgtt accttatttt ttagcagggc atcatgcttt
    12841 tacgtataga aacgacttat tatttattgc atctggtatg gttattatta gtttggtagt
    12901 tgcgcaagta ttattgccat tattaacgaa acctgcacct aaaacagtaa ttggcaatat
    12961 gtcgtttaaa gttgctagaa tttatatatt agaacaagtt attgattatc taaatcaaaa
    13021 atctactttc gaaacaagtt ttaaatatgg taacgtgatt aaagaatatc atgataaatt
    13081 agcattttta aaaactgtag agaaagatga tgaaaactct aaagaattag aacgtctaca
    13141 aaaaattgct tttaatgtag aaacaaaaac attagagtct ttagtagatg aaggacaaat
    13201 aacgaatagt gtacttgaaa actatatgcg ttatgctgaa agaacacagg tatatagaca
    13261 agcatcatta ataagaagaa tgattgtatt attacgaggt gctttattaa aacgaagagt
    13321 acaaacgaga gtgaactccg catcttcact tagtgttacg gataacttaa tggaattaaa
    13381 taaaattaat aaattagtcc attataatgt ggttagtcgt ttgtctaagg aaacaacaaa
    13441 agataataca cttgaaattg gaatggtttg tgacggttat ttaatgcgaa ttgaaaactt
    13501 aacaccatca aatttcttca actcagcaag tgaagatacg attactaaaa ttaaattaaa
    13561 tgcattgaga gaacaacgtc gcattttacg tgagttgatt gatacagatg aagtatcaga
    13621 aggtacagcg ttaaaactaa gagaagccat caattatgat gaaatggtta ttgtagatag
    13681 tatgacgtag ttcctaatta tgctaaaagg gattgatgaa aa
//
LOCUS       DAPDIM010000068        13709 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000068 DAPDIM010000000
VERSION     DAPDIM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13709
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.068"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            309..1004
                     /gene="sceD"
                     /locus_tag="RFE25_002262"
     CDS             309..1004
                     /gene="sceD"
                     /locus_tag="RFE25_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase SceD"
                     /protein_id="HDU2817298.1"
                     /translation="MKKTLLASSLAVGLGIVAGNAGHEAHASEADLNKASLAQMAQSN
                     DQTLNQKPIEAGAYNYTFDYEGFTYHFESDGTHFAWNYHATGANGANMSAQAPATNNV
                     EPSAVQANQVQSQEVEAPQNAQTQQPQASTSNNSQVTATPTESKASEGSSVNVNAHLK
                     QIAQRESGGNIHAVNPTSGAAGKYQFLQSTWDSVAPAKYKGVSPANAPESVQDAAAVK
                     LYNTGGAGHWVTA"
     regulatory      1209..1311
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            1391..2080
                     /gene="tenA"
                     /locus_tag="RFE25_002263"
     CDS             1391..2080
                     /gene="tenA"
                     /locus_tag="RFE25_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HDU2817299.1"
                     /translation="MEFSQKLYQAAKPIINDIYEDDFIQKMLSGDIGADALRHYLKAD
                     AAYLKEFTNLYALLIPKMNSMNDVKFLVEQIEFMVEGEVLAHDILAQIVGESYEEIIK
                     TKVWPPSGDHYIKHMYFQAHSRENAIYTIAAMAPCPYIYAELAKRSQSDHKLNREKDT
                     AKWFDFYSTEMDDIINVFEALMNKLAESMSDKELEQVKQVFLESCIHERRFFNMAMTL
                     EQWEFGGKVND"
     gene            2073..2903
                     /gene="thiD"
                     /locus_tag="RFE25_002264"
     CDS             2073..2903
                     /gene="thiD"
                     /locus_tag="RFE25_002264"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDU2817300.1"
                     /translation="MIKPKIALTIAGTDPTGGAGVMADLKSFHSCGVYGMGVVTSIVA
                     QNTLGVQHIHNLNHQWVDEQLDSVFNDTLPHAIKTGMIATADTMETIRHYLMQHESIP
                     YVIDPVMLAKSGDSLMDNDTKQNLQHTLLPLADVVTPNLPEAEEITGLTIDSEEKIMQ
                     AGRIFINEIGSKGIIIKGGHSNDTDIAKDYLFTNEGVQTFENERFKTKHTHGTGCTFS
                     AVITAELAKGRPLFEAVHKAKKFISMSIQYTPEIGRGRGPVNHFAYLKKEGLDDELSK
                     "
     gene            2887..3678
                     /gene="thiM"
                     /locus_tag="RFE25_002265"
     CDS             2887..3678
                     /gene="thiM"
                     /locus_tag="RFE25_002265"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDU2817301.1"
                     /translation="MNYLNKIRIENPLTICYTNDVVKNFTANGLLSIGASPAMSEAPE
                     EAEEFYKVAQALLINIGTLTAQNEQDIIAIAQTANEAGLPIVFDPVAVGASTYRKQFC
                     KLLLKSAKVSVIKGNASEILALIDDTATMKGTDSDANLDAVAIAKKAYAIYKTAIVIT
                     GKEDVIVQDNKAIVLANGSPLLARVTGAGCLLGGVIAGFLFRETEPDIEALIEAVSVF
                     NIAAEVAAENENCGGPGTFSPLLLDTLYHLNETTYQQRIRIQEVE"
     gene            3680..4321
                     /locus_tag="RFE25_002266"
     CDS             3680..4321
                     /locus_tag="RFE25_002266"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDU2817302.1"
                     /translation="MFNQSYLNVYFICGTSDVPSHRTIHEVLEAALKAGITLFQFREK
                     GESALKGNDKLVLAKELQHLCHQYDVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIA
                     QYFTDKIIGLSISDLDEYAKSDLTHVDYIGVGPIYPTPSKHDAHIPVGPEMIATFKEM
                     NPQLPIVAIGGINTNNVAPIVEAGANGISVISAISKSENIEKTVNRFKDFFNN"
     gene            4407..5279
                     /gene="yidC"
                     /locus_tag="RFE25_002267"
     CDS             4407..5279
                     /gene="yidC"
                     /locus_tag="RFE25_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDU2817303.1"
                     /translation="MKKKALLPLFLGIMVFLAGCDYSKPEKRSGFFYNTFVDPMKNVL
                     DWLGNNLLNDNYGLAIIILVLVIRIILLPFMLSNYKNSHMMRQKMKVAKPEVEKIQEK
                     VKRARTQEEKMAANQELMQVYKKYDMNPIKSMLGCLPMLIQLPIIMGLYFVLKDQLVD
                     GLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMI
                     IWISLSSASALGLYWSVSAAFLVVQTHFANIYYEKVAKKEVQPFIEAYEREHNGGSNK
                     KGKNTQVVSKKKKK"
     gene            complement(6192..6839)
                     /locus_tag="RFE25_002268"
     CDS             complement(6192..6839)
                     /locus_tag="RFE25_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDU2817304.1"
                     /translation="MQQSDVISAAKKYMESIHQNDYTGHDIAHVYRVTALAKSIAENE
                     GVNDTLVIELACLLHDTVDEKVVDANKQYVELKSFLSSLSLSTEDQEHILFIINNMSY
                     RNGKNDHVTLSLEGQIVRDADRLDAIGAIGVARTFQFAGHFGEPMWTEHMSLDKINDD
                     LVEQLPPSAIKHFFEKLLKLESLMHTDTAKMIAKERHDFMMMYLKQFFTEWNYHD"
     gene            complement(6867..8351)
                     /gene="cls"
                     /locus_tag="RFE25_002269"
     CDS             complement(6867..8351)
                     /gene="cls"
                     /locus_tag="RFE25_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDU2817305.1"
                     /translation="MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANS
                     IWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENF
                     SNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQ
                     YYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFF
                     PSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGD
                     AVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGY
                     LKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKN
                     AASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQI
                     AKKLKQAFIDDLAVSSELTKARYAKRSLWIKFKEGISQLLSPIL"
     gene            8517..8810
                     /gene="csoR"
                     /locus_tag="RFE25_002270"
     CDS             8517..8810
                     /gene="csoR"
                     /locus_tag="RFE25_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-sensing transcriptional repressor CsoR"
                     /protein_id="HDU2817306.1"
                     /translation="MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDV
                     LTQIRATRSALNSVAIKLLEQHMKSCIMNKVNQGAQEEAMEELLVTFQKLIKD"
     gene            8822..9031
                     /locus_tag="RFE25_002271"
     CDS             8822..9031
                     /locus_tag="RFE25_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDU2817307.1"
                     /translation="MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVT
                     VSYETPANLNSIEKEIYDEGYKIVF"
     gene            9159..9296
                     /locus_tag="RFE25_002272"
     CDS             9159..9296
                     /locus_tag="RFE25_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817308.1"
                     /translation="MKRPEKIQNVVKLLSSLGVNIKKTKSRLDIINTLPASNKVSHEL
                     K"
     gene            complement(9560..10762)
                     /locus_tag="RFE25_002273"
     CDS             complement(9560..10762)
                     /locus_tag="RFE25_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDU2817309.1"
                     /translation="MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQ
                     YSANFGIRQIFYYILGAIFAGIIMFISPKKIKHYTYLLYFLICLLLIGLLVIPESPIT
                     PIINGAKSWYTFGPISIQPSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKII
                     GVSLVPSILILLQNDLGTTLVLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGI
                     LYAPALIENLLGVQLYQMGRINSWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHG
                     EVYIPENHTDFIFSVIGEELGFIGSVILILIFLFLIFHLIRLAAKIEDQFNKIFIVGF
                     VTLLVFHILQNIGMTIQLLPITGIPLPFISYGGSALWSMMTGIGIVLSIYYHEPKRYV
                     DLYHPKSN"
     gene            11080..12150
                     /locus_tag="RFE25_002274"
     CDS             11080..12150
                     /locus_tag="RFE25_002274"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDU2817310.1"
                     /translation="MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYIT
                     NDGDWRKQNNITAEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGED
                     GTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEH
                     NILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNA
                     REIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNM
                     ALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYPELI
                     TKLIELAKERHQDKQKNKYKID"
     gene            12165..13523
                     /locus_tag="RFE25_002275"
     CDS             12165..13523
                     /locus_tag="RFE25_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDU2817311.1"
                     /translation="MINVTLKQIQSWIPCEIEDQFLNQEINGVTIDSRAISKNMLFIP
                     FKGENVDGHRFVSKALQDGAGAAFYQRGTPIDENVSGPIIWVEDTLTALQQLAQAYLR
                     HVNPKVIAVTGSNGKTTTKDMIESVLHTEFKVKKTQGNYNNEIGLPLTILELDNDTEI
                     SILEMGMSGFHEIEFLSNLAQPDIAVITNIGESHMQDLGSREGIAKAKSEITIGLKDN
                     GTFIYDGDEPLLKPHVKEVENAKCISIGVATDNALVCSVDDRDTTGISFTINNKEHYD
                     LPILGKHNMKNATIAIAVGHELGLTYNTIYQNLKNVSLTGMRMEQHTLENDITVINDA
                     YNASPTSMRAAIDTLGTLTGRRILILGDVLELGENSKEMHIGVGNYLEEKHIDVLYTF
                     GNEAKYIYDSGQQHVEKAQHFNSKDDMIEVLTSDLKAHDRVLVKGSRGMKLEEVVNAL
                     IS"
BASE COUNT         4929 a         2152 c         2475 g         4153 t
ORIGIN      
        1 caattaaaaa cgacttacat gactagtact gttgtgtagg tcgtcttttt gtgtagtttt
       61 tctaatagaa aatagacata gattgcaaaa cgattacata aaaaattgca aataaaaaac
      121 atttttactg tcatgacaat tctcgataga atcatatctg aaattatggg ggatttcgtt
      181 gtaatcactg tgtaaaaaac aaggctattt ttttattttg ttgtaacctg cacggatttt
      241 atagatgtta cagtagtctc tgtaaaactt ttagagaaac aaattacttg taggaggatt
      301 ttaagattat gaagaaaaca ttactcgcat catcattagc agtaggttta ggaatcgtag
      361 caggaaatgc aggtcacgaa gcccatgcaa gtgaagcgga cttaaataaa gcatctttag
      421 cgcaaatggc gcaatcaaat gatcaaacat taaatcaaaa accaattgaa gctggggctt
      481 ataattatac atttgactat gaagggttta cttatcactt tgaatcagat ggtacacact
      541 ttgcttggaa ttaccatgca acaggtgcta atggagcaaa catgagtgca caagcacctg
      601 caactaataa tgttgaacca tcagctgttc aagctaatca agtacaatca caagaagttg
      661 aagcaccaca aaatgctcaa actcaacaac cacaagcatc aacatcaaac aattcacaag
      721 ttactgcaac accaactgaa tcaaaagcat cagaaggttc atcagtaaat gtgaatgctc
      781 atctaaaaca aattgctcaa cgtgaatcag gtggcaatat tcatgctgta aatccaacat
      841 caggtgcagc tggtaagtat caattcttac aatcaacttg ggattcagta gcacctgcta
      901 aatataaagg tgtatcacca gcaaatgctc ctgaaagtgt tcaagatgcc gcagcagtaa
      961 aattatataa cactggtggc gctggacatt gggttactgc ataagccatt tatgcatagc
     1021 taatcaatag ttatataagt aacttttaga tcggaatata tcggggaatt ctcgatatgt
     1081 tccggtcttt tttatttcgc aaatatacgt cattatagaa ttattattta aagataataa
     1141 tacaactgag caacaataat tgaaaatgtt gaaaccgttt gctaagatta atttgcaatt
     1201 gaatactaag gaactactag gggagcctaa tgatatggct gagatgaatt gttcagaccc
     1261 ttatgacctg atttggttag taccaacgta ggaaagtagt tattgaagtg atggggctag
     1321 tatagcaaca ttgccatcaa actactttca tgttggaagt agttttttta tttagggagg
     1381 attttttaca atggaatttt cacaaaaatt gtaccaagct gcaaagccaa tcattaatga
     1441 tatttatgag gatgacttta ttcagaagat gttatccgga gatataggag ctgacgcatt
     1501 acgccattac ttaaaagctg atgctgcgta tttaaaagaa tttacaaact tatatgcttt
     1561 gttaattcca aaaatgaata gcatgaatga cgtaaaattt ttagtagagc aaatagaatt
     1621 tatggttgaa ggtgaagtac ttgcgcatga tattttagcg caaattgttg gtgaatcata
     1681 cgaagaaatc attaaaacaa aagtttggcc tccaagtggc gaccattaca taaaacatat
     1741 gtatttccaa gcgcatagtc gtgaaaatgc tatttataca attgctgcaa tggcaccttg
     1801 tccatatatt tatgcagaat tagctaagcg ctctcaaagt gatcataagc ttaatagaga
     1861 aaaagatacg gcaaaatggt ttgattttta tagtactgaa atggatgaca taattaacgt
     1921 atttgaggca ttaatgaata aattagccga atcaatgtct gacaaggaat tggaacaagt
     1981 aaagcaagta tttttagaaa gttgcataca tgagcgtcga tttttcaata tggctatgac
     2041 actagaacaa tgggaatttg gaggaaaagt aaatgattaa acctaaaata gcattaacca
     2101 ttgcaggtac tgatccaaca ggtggtgccg gcgtaatggc tgatttaaaa tcatttcatt
     2161 catgtggtgt atatggtatg ggcgtcgtta caagtattgt tgctcaaaat acattgggcg
     2221 tacaacatat tcataattta aatcatcaat gggtagatga acaacttgat agtgtcttca
     2281 atgatacctt acctcatgct attaaaacgg ggatgattgc tacagcagat actatggaaa
     2341 cgattcgtca ttatttaatg caacatgaat ctattccata tgtaattgat cctgttatgt
     2401 tggcgaaaag cggtgattca ttaatggata atgacacaaa gcaaaacttg cagcatacgt
     2461 tattgccatt agctgacgta gtaacaccga atttaccaga agctgaagaa ataacgggac
     2521 taaccattga tagtgaagaa aaaattatgc aggctggccg catctttatt aatgagattg
     2581 gtagtaaagg tatcatcatt aaaggcggtc attcaaatga tactgatata gcaaaagatt
     2641 atttatttac taacgaaggt gttcaaacat ttgaaaatga acgatttaaa acaaaacata
     2701 cgcatggaac agggtgtaca ttttcagcag ttataacggc agaacttgca aaaggtagac
     2761 cattatttga ggctgtacac aaggctaaaa agtttatttc aatgagtata caatatacac
     2821 ctgaaatcgg ccgtggtaga ggaccagtga atcattttgc atatttaaag aaagagggat
     2881 tagacgatga attatctaaa taaaatacgt attgaaaacc cattaacaat ttgttataca
     2941 aacgatgtag ttaaaaattt tacagcgaat ggtttattaa gtattggtgc gagccctgcc
     3001 atgagtgaag ctcccgaaga agctgaagaa ttttacaaag ttgcacaagc gctattaatc
     3061 aatatcggta ctttaacagc acaaaatgaa caagatatta ttgcgattgc tcaaacggca
     3121 aatgaggcag gcttacctat tgtatttgac cctgtagctg ttggtgcttc tacatatcga
     3181 aagcaatttt gtaaattatt attgaaatca gcgaaagtat cagtaattaa aggcaatgca
     3241 tctgaaatat tagcgttgat tgatgataca gcaactatga aaggtacaga tagtgatgct
     3301 aatcttgatg cggttgcaat agcgaaaaag gcttacgcaa tatataaaac tgcaatagta
     3361 atcacaggta aagaggacgt tattgttcaa gataataaag ccatcgtatt agctaatgga
     3421 tctccattat tagcacgagt aactggagct ggttgtttat taggaggcgt tattgctgga
     3481 tttttattta gagaaacaga accagacata gaagcgttaa ttgaagcggt aagcgtattt
     3541 aatattgctg ctgaggtagc tgctgaaaat gaaaattgtg gtggtcctgg tacgttttca
     3601 ccattgttgc ttgatacgtt atatcattta aatgaaacaa cctatcaaca acggattcgt
     3661 attcaagagg tggaataata tgtttaacca atcgtatcta aatgtgtatt ttatttgtgg
     3721 gacctccgat gttccgagtc atcgaactat tcatgaagta ttagaagcag cattaaaggc
     3781 agggattaca cttttccaat ttcgagaaaa gggtgaatca gctttaaaag gaaacgataa
     3841 acttgtatta gctaaagaat tacagcatct ctgtcatcaa tatgatgtgc cttttatcgt
     3901 taatgatgat gtatccttgg caaaagaaat taacgcggat ggtatacatg tcggtcaaga
     3961 tgatgcgaaa gtcaaagaga tagcacaata tttcactgat aaaattattg gacttagtat
     4021 tagtgattta gatgagtatg caaaatctga tttaactcat gttgattata taggtgttgg
     4081 accaatctat cctacgccgt cgaagcatga cgcgcatata ccagtaggtc cagaaatgat
     4141 tgcaacgttt aaagaaatga atccgcaact accgattgta gctattggcg gtatcaatac
     4201 taataatgtg gcgccgattg tagaagcagg tgccaatgga atttcagtca tttcagccat
     4261 ttctaaaagt gaaaatattg aaaagactgt taatcgattc aaagattttt ttaataatta
     4321 gttaaatttt tccacttatt gtttcatacg tactcattaa tgtgatagaa taaatcctat
     4381 gtgaatataa tgatagaggt ggaaaaatga agaaaaaagc gttactacca ttatttttag
     4441 gtattatggt ctttttggct ggttgtgact attctaaacc tgaaaaacgt agtgggtttt
     4501 tctacaatac attcgtagat ccaatgaaaa atgtattgga ttggttggga aataacttat
     4561 taaacgacaa ttatggttta gctattatta tccttgtatt ggtaattcgt attattttat
     4621 taccattcat gttgtcaaac tataaaaata gtcatatgat gcgtcaaaaa atgaaagttg
     4681 caaagccaga agttgaaaaa attcaagaaa aagtgaaacg tgcgcgtaca caagaagaaa
     4741 aaatggctgc aaaccaagaa ttaatgcaag tatataaaaa gtatgacatg aacccgatta
     4801 agagtatgtt gggttgttta ccaatgctaa tccaattgcc aatcatcatg ggattatact
     4861 ttgtacttaa agaccaactt gtagatggtt tgtttaaata tccacacttc ttatggttcg
     4921 atttaggacg tcctgatatt tggattacaa ttattgccgg tgttttatac tttatccaag
     4981 catatgtatc aagtaaaacg atgccagacg aacaacggca aatgggttac atgatgatgg
     5041 tcatttcacc aattatgatt atctggattt cattaagctc agcatcagca cttggtttgt
     5101 actggtctgt cagtgcggcg ttccttgtag ttcaaacaca ctttgcgaac atttattatg
     5161 aaaaagtcgc taaaaaagaa gtacaacctt tcattgaagc gtatgaaaga gagcacaacg
     5221 gcggcagcaa taaaaaaggc aaaaacacac aagtagtgtc taaaaagaaa aagaaataac
     5281 cttagcaagt ccaaataatg tgcaccctaa aagttgaaga taattttaac tttatagggc
     5341 gcgcattatt tttcgcttca atagcgaaac ttagtgtcac attatacaat atgtgataaa
     5401 tagaaacagc agtaagatga tttcaaatgt gaaagtcatc ctactgctgt ttttatttga
     5461 aataatatta acgagatttc agtatgtaaa aagtggttaa taacagagtt gtcattcttc
     5521 atcgcaatgt catcttgaca caatgattca tcagtgtagc agtatatgtc gcaaatttcc
     5581 acagtaattc actaatacat gtaacagtgt gaaatactaa catcacaacg gcataataca
     5641 cattgcaacg tcccaacaac atatcataga atagtaacgg catggcatca acaccaaacc
     5701 gggctataat accataacac cgcaacgcca catcatagca ctacatcaag tcgcatcgta
     5761 gcaccagcac atcaaagtaa catggcatca acatcaaacc ggtctataac accataacag
     5821 cgcaacgcca catcatagca ctacatcaag tcgcatcgtg gtaccagcac atcaaagtaa
     5881 catggcatca acgccaaacc ggtctataac accataacac cgcaatgcca catcatagca
     5941 ctacatcaag acgcatcgtg gtaccagcac atcaaagtag catggcatcg acgccaaacc
     6001 ggtctataac accataacac cgcaatgcca catcatagca ctacatcaag acgcatcgtg
     6061 gtaccagcac atcaaagtaa catgacatga caccaagctc ccacaacaac acatcaaagt
     6121 aacatggcat gacaccaagc ttccacaaca acacgccatt acatcgcatc atcatactac
     6181 aacttcaatg tctagtcgtg ataattccat tccgtaaaaa actgtttcaa gtacatcatc
     6241 ataaagtcgt gacgttcttt agcaatcatc ttcgccgtat ctgtatgcat taaagattct
     6301 aacttaagta atttttcaaa gaaatgttta attgcagatg gtggcaactg ttcaactaaa
     6361 tcatcattaa tcttatctag tgacatatgt tctgtccaca ttggttcacc aaagtgtcct
     6421 gcaaattgaa atgttcgtgc aacacctata gcgcctatag catcaagacg atctgcatcc
     6481 ctgacaattt gaccttctaa agataaagtg acatgatcgt ttttgccatt gcgatagctc
     6541 atattattaa taataaataa aatatgctct tgatcttcgg ttgatagtga taaagaagat
     6601 aaaaatgact tcaattcaac atattgtttg ttagcatcta caactttttc gtcaacggta
     6661 tcatgaagca aacatgcgag ttcaatgact aaagtatcat taacaccttc attttcagcg
     6721 attgatttag ctaaagcagt gacacgatat acatgcgcaa tatcatggcc tgtataatca
     6781 ttttgatgaa tagattccat atattttttg gcagcactaa tgacgtctga ttgttgcatt
     6841 aaagttacac tcctcatatt tctattttat aagataggtg acaataattg tgaaatacct
     6901 tctttaaatt taatccaaag acttcgctta gcataacgtg cttttgttaa ttcagaagat
     6961 actgctaaat catctataaa agcttgtttt aattttttgg caatttgttg gtcataaata
     7021 aaagcgttga cttcgaaatt caatgtgaaa ctgcgatggt ccatattagc tgttcccaca
     7081 cttgcaattt catcatctat aacaagtgtt tttgagtgta aaaagccatt gtcgtagtga
     7141 aatactttaa caccggcatc taataaggat gctgcatttt ttaaagtagc ccaaaaaaca
     7201 aacggatggt caggtttatt aggaatcatg atattgacat caacaccacc taatgccgca
     7261 attttaatag aatctaaaaa ggcttgatca ggtatgaaat agggagattg aatataaatc
     7321 gattttttag cagatgaaat cattttcaaa tagccgtatt taatctgttc ccattcttcg
     7381 tcaggaccac tagaagctat ttgaacgcca attgttccac cagaatttac atctgggaaa
     7441 taacgatcat cataggagat gtggtcacgt gtggcttgtg aattccaatc tagaataaat
     7501 cgtaattgca atgcattcac tgcatccccg acaattcgta aatgcgtatc tcgccaatag
     7561 ccgaattttt ttgatttacc taagtactca tcaccaacat taaaaccacc aacatatcca
     7621 atttgcccat ctattacaac aatttttcga tggtttcgat tgttcatacg caagttaatt
     7681 aaaggtaatt ttgatgggaa aaatgcttca gcatgtccac ctttattgcg aaacgggcgt
     7741 aagccttttt tacgcagtcc acgagaaccc atgtcatcat aaagaatttt aacttctaca
     7801 ccttgttccg cttttttacc aagttcattt aaaatggtac gacctaattc atcattttga
     7861 ataatatagt attgaaaatg aatataatca gtagcattac ggatgtcttg tattaggtca
     7921 tcaaattttt cttggccgtc tgtgtatatt tttaaatcgt tgtctgttgt taaaaatgct
     7981 gcgttattat ataacaacat ttgaatcatt tctttaaatt ttacaatttg ataattggaa
     8041 tttgaaaagt tttcattttt taaagcagct aattgctcat caacgattaa ctctaatcct
     8101 tttttatctt ccttatcaat tttgaaaatt tggtcacgtt gaatttgtcg tcctaatagt
     8161 aagtataaaa tgaagccgaa taaaggcaag aaaactaaga ctagtaacca agcccagata
     8221 gaattggcag aacgtctttc catgaaaata atggtaaagg cgaataataa gtttaaaata
     8281 aatgcaccaa taaatattga atttaaaata atattagaat gcttgagtgc aatggataat
     8341 aactctatca tttgaaacct cccatcgaaa atcttaaacg agtagtatat cttattaatt
     8401 gtatcatgaa gcaatttaaa tatcatgaca atttagtttg aaaaacacac tttgtgttga
     8461 cgttgtgttt tatgggatat agtatagtaa ggaatgtaaa tgaaggagtg aatgctatga
     8521 ctgaacaaga taatgcacat cattctgaac aaataaaaac gaatcttaaa tcacgtttaa
     8581 atcgaattga aggacaagtg agagcgatta atcgcatgat tgaagaagat gtctattgtg
     8641 atgatgtcct tacgcaaata agagcgacac gttcggcgtt aaacagtgtt gcgataaagt
     8701 tattagaaca acatatgaaa agttgtatta tgaataaagt taatcaaggt gctcaggaag
     8761 aggcaatgga agagttatta gtgacttttc aaaaattgat taaagactaa aggagtttaa
     8821 gatgatacat caaaatacga tttacacagc gggaattgaa acagaagaac aagtaagtca
     8881 attgacagaa cgcatttcaa atatgatagg tgttcatcaa gtgaatatta atataataga
     8941 tggtcaagta actgtatcgt atgagacacc agcaaatttg aatagtattg aaaaagaaat
     9001 ctatgatgaa ggatacaaaa ttgtatttta gggtataatg tagagtgcgc tatagatttt
     9061 aattttgaaa ataaattaaa aattttgtaa atgatgtagt aaaggtatgt cgaatagggt
     9121 aagataatat tgaaagcgat ccaaacgagg tgataataat gaaacgtcct gaaaagattc
     9181 aaaatgtagt caaactattg tcatcattag gtgtgaatat taaaaaaact aaatctcgtt
     9241 tagacattat taatactttg ccagcatcta ataaagtaag tcacgaatta aaataattga
     9301 ctgtgattgt gaatcacaca ccgttaaagc tatcgtcgga ctattcgatg atagcttttt
     9361 tgactggatt tactaaaatg aaagcaagta ctatataaca aaatccctct ttagagtgta
     9421 cattttacaa tgtgtacttc aaagagggat tgttattatc gagtaatatc tatatatgac
     9481 attttaaatc gacgacgtaa atagactata taacgtcatc ttgaaaagtt atgatatttg
     9541 aaactcaaaa tagtttaaat taattacttt ttggatggta taaatcgaca tatcgttttg
     9601 gttcatgata ataaattgat aagactatac ctattccagt catcatactc catagcgcac
     9661 taccaccata actaataaat ggtaatggaa taccagtgat tggtaacaac tgaattgtca
     9721 taccaatatt ttgtaaaata tggaacacaa gtaaagtgac gaaaccaacg ataaagattt
     9781 tgttaaattg atcttcaatt ttcgcagcta atcttattag atggaagatt aaaaataaaa
     9841 atattaagat caatatgaca gaaccgataa agccaagttc ctctccaatc actgaaaaga
     9901 taaagtcagt atgattttca ggtatataaa cttcaccgtg attgtatcct ttacctagta
     9961 actgtccaga accgatagct ttaagtgatt cagttaaatg atagccatca ccactactat
    10021 atgtataggg gtcaagccat gaattgattc gtcccatttg atacagttgg acacctaata
    10081 aattttcaat taatgcgggt gcatatagaa tacctaaaat gactgtcatt gcaccaacaa
    10141 tacctgtaat aaagataggt gctaagatac gccatgttat accacttact aacatcacac
    10201 ctgcaataat agcagctaat actaatgtag ttcctaggtc attttgcagt aatattaaaa
    10261 tacttggtac taacgagaca ccaataattt tgaaaaataa taacaaatca ctttggaatg
    10321 atttattgaa tgtgaattga ttatgtctag aaacgacacg cgctaatgct aaaattaaaa
    10381 taattttcat gaattcagat ggctgaatac tgatagggcc aaacgtgtac caacttttgg
    10441 caccattgat aataggtgta ataggtgact caggaataac gagcaagcct attaataata
    10501 gacagattaa gaaatacaat aaatatgtat aatgtttaat ctttttaggt gaaataaaca
    10561 tgatgatacc tgcaaaaatt gcacctaaaa tgtaataaaa aatttgtctg ataccgaaat
    10621 tagcactgta ttgaccaccg cccattgccg agttaataag cagaacactg aaaattgcta
    10681 aaacagctat agtggctact aatacccagt ctactttgcg aagccaatgc ttatccggct
    10741 gttgacgaga tgaataattc attgcaaact ccttttatac tcactaatgt ttatatcaat
    10801 tttacatgac tttttaaaaa ttagctagaa tatcacagtg atatcagcta tagatttcaa
    10861 tttgaattag gaataaaata gaagggaata ttgttctgat tataaatgaa tcaacataga
    10921 tacagacaca taagtcctcg tttttaaaat gcaaaatagc attaaaatgt gatactatta
    10981 agattcaaag atgcgaataa atcaattaac aataggacta aatcaatatt aatttatatt
    11041 aaggtagcaa accctgatat atcattggag gaaaacgaaa tgacaaaaga aaatatttgt
    11101 atcgtttttg gagggaaaag tgcagaacac gaagtatcga ttctgacagc acaaaatgta
    11161 ttaaatgcaa tagataaaga caaatatcat gttgatatca tttatattac caatgatggt
    11221 gattggagaa agcaaaataa tattacagct gaaattaaat ctactgatga gcttcattta
    11281 gaaaatggag aggcgcttga gatttcacag ctattgaaag aaagtagttc aggacaacca
    11341 tacgatgcag tattcccatt attacatggt cctaatggtg aagatggcac gattcaaggg
    11401 ctttttgaag ttttggatgt accatatgta ggaaatggtg tattgtcagc tgcaagttct
    11461 atggacaaac ttgtaatgaa acaattattt gaacatcgag ggttaccaca gttaccttat
    11521 attagtttct tacgttctga atatgaaaaa tatgaacata acattttaaa attagtaaat
    11581 gataaattaa attacccagt ctttgttaaa cctgctaact tagggtcaag tgtaggtatc
    11641 agtaaatgta ataatgaagc ggaacttaaa gaaggtatta aagaagcatt ccaatttgac
    11701 cgtaagcttg ttatagaaca aggcgttaac gcacgtgaaa ttgaagtagc agttttagga
    11761 aatgactatc ctgaagcgac atggccaggt gaagtcgtaa aagatgtcgc gttttacgat
    11821 tacaaatcaa aatataaaga tggtaaggtt caattacaaa ttccagctga cttagacgaa
    11881 gatgttcaat taacgcttag aaatatggca ttagaggcat tcaaagcgac agattgttct
    11941 ggtttagtcc gtgctgattt ctttgtaaca gaagacaacc aaatatatat taatgaaaca
    12001 aatgcaatgc ctggatttac ggctttcagt atgtatccaa agttatggga aaatatgggc
    12061 ttatcttatc cagaattgat tacaaaactt atcgagcttg ctaaagaacg tcaccaggat
    12121 aaacagaaaa ataaatacaa aattgactaa ctgaggttgt tattatgatt aatgttacat
    12181 taaagcaaat tcaatcatgg attccttgtg aaattgaaga tcaattttta aatcaagaga
    12241 taaatggagt cacaattgat tcacgagcaa tttctaaaaa tatgttattt ataccattta
    12301 aaggtgaaaa tgttgacggt catcgctttg tctctaaagc attacaagat ggtgctgggg
    12361 ctgcttttta tcaaagaggg acacctatag atgaaaatgt aagcgggcct attatatggg
    12421 ttgaagacac attaacggca ttacaacaat tggcacaagc ttacttgaga catgtaaacc
    12481 ctaaagtaat tgccgtcaca gggtctaatg gtaaaacaac gactaaagat atgattgaaa
    12541 gtgtattgca taccgaattt aaagttaaga aaacgcaagg taattacaat aatgaaattg
    12601 gtttaccttt aactattttg gaattagata atgatactga aatatcaata ttggagatgg
    12661 ggatgtcagg tttccatgaa attgaatttc tgtcaaacct cgctcaacca gatattgcag
    12721 ttataactaa tattggtgag tcacatatgc aagatttagg ttcgcgcgag gggattgcta
    12781 aagctaaatc tgaaattaca ataggtctaa aagataatgg tacgtttata tatgatggcg
    12841 atgaaccatt attgaaacca catgttaaag aagttgaaaa tgcaaaatgt attagtattg
    12901 gtgttgctac tgataatgca ttagtttgtt ctgttgatga tagagatact acaggtattt
    12961 catttacgat taataataaa gaacattacg atctgccaat attaggaaag cataatatga
    13021 aaaatgcgac gattgccatt gcggttggtc atgaattagg tttgacatat aacacaatct
    13081 atcaaaattt aaaaaatgtc agcttaactg gtatgcgtat ggagcaacat acattagaaa
    13141 atgatattac tgtgataaat gatgcctata atgcaagtcc tacaagtatg agagcagcta
    13201 ttgatacact gggtactttg acagggcgtc gcattctaat tttaggagat gttttagaat
    13261 taggtgaaaa tagcaaagaa atgcatatcg gtgtaggtaa ttatttagaa gaaaagcata
    13321 tagatgtgtt gtatacgttt ggtaatgaag cgaagtatat ttatgattcg ggccagcaac
    13381 atgtcgaaaa agcacaacac ttcaattcta aagacgatat gatagaagtt ttaacaagcg
    13441 atttaaaagc gcatgaccgt gtattagtta aaggatcacg tggtatgaag ttagaagaag
    13501 ttgtaaatgc tttaatttca tagagattag tcgagcgacc ttttacttat aaaaatgatt
    13561 tgaattaata ctaaaagatt acaaagaaga ggtggttttg tgtgtaaata caaaattgcc
    13621 tttttctttt tatgttaaat ctataaattt gaaactaaat caaggttaat tctatgtaca
    13681 cactttatat aggaagtagt ttgaatgtt
//
LOCUS       DAPDIM010000069        13399 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000069 DAPDIM010000000
VERSION     DAPDIM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13399
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.069"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(35..1588)
                     /locus_tag="RFE25_002276"
     CDS             complement(35..1588)
                     /locus_tag="RFE25_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HDU2817312.1"
                     /translation="MSEEKHVVEHEQQKKEKTKKQYKPFWIVMSFIILIVVLLLPAPS
                     SLPIMAKAVLAILAFAVIMWVTEAVSYPVSATLIIGLMILLLGFSPVQNLGEKLGNPK
                     SGSAILAGSDLLGTNHALSLAFSGYATSAVALVAAALFLAAAMQETNLHKRLALLVLS
                     IVGNKTRNIVIGAIIVSIVLAFFVPSATARAGAVVPILLGMIAAFKVSKDSKLASLLI
                     ITSVQAVSIWNIGIKTAAAQNIVAINFINHQLGFDVSWGEWFLYAAPWSIVMSVALYF
                     IMIKVMPPEINTIEDGKDLIKEELHKLGPVSPREWRLIVISMLLLLFWSTEKVLHPID
                     SASITIIALGVMLMPKIGVMTWKHVENKIPWGTIIVFGVGISLGNVLLKTGAAQWLSD
                     QTFGVLGLKHLPIIATIALITLFNILIHLGFASATSLSSALIPVFISLTSTLHLGDQS
                     IGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKAGIPLTIVGYILVIVFSM
                     TYWKWLGLL"
     gene            complement(1871..2158)
                     /locus_tag="RFE25_002277"
     CDS             complement(1871..2158)
                     /locus_tag="RFE25_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817313.1"
                     /translation="MTNEDKRFEQLRFERKFIVIPYLIYAVIVLLLNIFYSDLKITMT
                     LFGLFFAYNVVILFIAFIKHYKRTLLLSLILTVLSGAAFFGIIYVYGINHF"
     gene            complement(2193..3101)
                     /locus_tag="RFE25_002278"
     CDS             complement(2193..3101)
                     /locus_tag="RFE25_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HDU2817314.1"
                     /translation="MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGI
                     TTMDHADIYGDYQCESLFGNALDLSPELRNKIQIVTKCGIILPSKQFDFTNGHRYDLS
                     SKHIVKSVEQSLINLNVDYLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNF
                     NHSQYQLLNQYIMKERLHISINQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGG
                     KIFDKEDIKAQRIMKVVQSIADKYGVSDTAVMIAWLVKIPHSIMPILGTSQLKRIDQA
                     IEGLQLNLDDQSWFDIYTAIIGQDIP"
     gene            complement(3204..4130)
                     /locus_tag="RFE25_002279"
     CDS             complement(3204..4130)
                     /locus_tag="RFE25_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDU2817315.1"
                     /translation="MKNNKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIM
                     NEFGTFDIDSNSISNEIEVHSLINGCVCCDLKQELVYELKAIALKGDVNHVIIEATGI
                     AHPLELLVACQDPQIVNFFEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMII
                     INKIDLITDDSLEKIDKQLGMICASIPTYKTTYGKVSLEELDLTVKDREISSHHHHHH
                     GIKSMTYTFTGPIDRQLFYQFIMKLPESVLRLKGYVSFRNQPNAIYEFQYAYGLPDYG
                     IIGMQLPLTIVIIGETLDTNHIRNQLDMLQFT"
     gene            4357..4800
                     /gene="mgrA"
                     /locus_tag="RFE25_002280"
     CDS             4357..4800
                     /gene="mgrA"
                     /locus_tag="RFE25_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MgrA"
                     /protein_id="HDU2817316.1"
                     /translation="MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVL
                     TILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKS
                     ETIRPELSNASDKVASASSLSQDEVKELNRLLGKVIHAFDETKEK"
     gene            complement(4927..6600)
                     /locus_tag="RFE25_002281"
     CDS             complement(4927..6600)
                     /locus_tag="RFE25_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding/permease
                     protein"
                     /protein_id="HDU2817317.1"
                     /translation="MKTRLKFQVDKDLLLAIVVGVCGSLVALAMFFLSGYMVTQSALG
                     APLYALMILVVTVKLFGFLRAITRYVERLISHKATFTMLRDIRVQFFGKLVNVIPNVY
                     RKLSSSDLISRMISRVEALQNIYLRVYYPPVVIGLTALVTVIVLAFISIGHALLIMVS
                     MLFTLLIVPWLSSKKARTLKKHAANEQARFLNHFYDYKAGMDELRRFNQINHYRDNLM
                     AKLNHFDKLQLKEQRFLTIYDFILNIIAMLSIFGSLVLGLIQINAGQLNIIYMTSIVL
                     MILTLFEQAVPMTNVAYYKADTDQALHDINEVISVPSTNGKKRLNDKYDATNIYEVKD
                     ASFKYWNQQTYVLSDINFNVNRGEKIAIVGPSGSGKSTLLQIMAGLYQLDSGSVRFEN
                     MDMFEIDDKDKFESLNVLLQSQQLFDGTIRQNLFTDEKDEAVQAIFKQLDLEHLALER
                     QIDLDGHTLSGGEIQRLAITRMLLKDTASTWILDEPTTALDKQNSLKVMDLIEAHAET
                     LIVATHDLTLLSRFETIIVMINGKIVEKGNYQQLLANQGALWNMIQYNA"
     gene            complement(6597..8228)
                     /locus_tag="RFE25_002282"
     CDS             complement(6597..8228)
                     /locus_tag="RFE25_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HDU2817318.1"
                     /translation="MKKLTTILFQYKIFPVLMFLVSTGLGILVITQNILIADFLAKII
                     RHQFQGLWIVLFILLGVLLLRATVQFLNQWLGDTLAFKVKHMLRQRVIYKNNGHPIGE
                     QMTILTENIDGLAPFYKSYLPQVFKSMMVPLIIIIAMFFIHFNTALIMLITAPFIPLF
                     YIIFGLKTRDESKDQMTYLNQFSQRFLNIAKGLVTLKLFNRTEQTEKHIYDDSTQFRT
                     LTMRILRSAFLSGLMLEFISMLGIGLVALEATLSLVVFHNIDFKTAAIAIILAPEFYN
                     AIKDLGQAFHTGKQSEGASDVVFEFLEQPNYNNEFLLKYEENQKPFIQLTDISFRYDD
                     SDRLVLNDLNLEIFKGDQIALVGPSGAGKSTLTHLIAGVYQPTIGTISTNQRDLNIGI
                     LSQQPYIFSASIKENITMFKDIENNTIEEVLDEVGLLDKVQSFTKGINTIIGEGGEML
                     SGGQMRRIELCRLLVMKPDLVIFDEPATGLDIQTEHMIQNVLFQHFKDTTMIVIAHRD
                     NTIRHLQRRLYIENGRLIADDRNISVNITENGDDL"
     gene            8447..9322
                     /locus_tag="RFE25_002283"
     CDS             8447..9322
                     /locus_tag="RFE25_002283"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDU2817319.1"
                     /translation="MFIIELIKGIILGVVEGLTEFAPVSSTGHMILVDDMWLKSSEFL
                     GSQSAFTFKIVIQLGSVFAAAWVFRERFLEILHIGKHKHVEGENDQQRRSKPRRLNLL
                     HVLVGMVPAGILGLLFDDFIEEHLFSVPTVMIGLFVGAIYMIIADKYSVKVKNPQTVD
                     QINYFQAFVIGISQAVAMWPGFSRSGSTISTGVLMKLNHKAASDFTFIMAVPIMLAAS
                     GLSLLKHYQDIQIADIPFYILGFLAAFTVGLIAIKTFLHLINKIKLIPFAIYRIVLVI
                     FIAILYFGFGIGKGI"
     gene            9494..10177
                     /locus_tag="RFE25_002284"
     CDS             9494..10177
                     /locus_tag="RFE25_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817320.1"
                     /translation="MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKV
                     ASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKD
                     ADKMNKILQKNIEKRHKEEQKAREKNEIQRIKDMKKSQKYEEKAGLTPNKLDEKTEKK
                     GDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQ
                     QNKENNTEA"
     gene            10180..10638
                     /locus_tag="RFE25_002285"
     CDS             10180..10638
                     /locus_tag="RFE25_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDU2817321.1"
                     /translation="MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPP
                     HVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKN
                     IQQLLDKRYINAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD"
     gene            10640..11206
                     /locus_tag="RFE25_002286"
     CDS             10640..11206
                     /locus_tag="RFE25_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HDU2817322.1"
                     /translation="MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIG
                     IMGAIQDGVLNHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFV
                     MAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYR
                     ALAPLCDTKESLIESILNFKPLGTRSYD"
     gene            complement(11302..11844)
                     /locus_tag="RFE25_002287"
     CDS             complement(11302..11844)
                     /locus_tag="RFE25_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2817323.1"
                     /translation="MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRS
                     ELDMRTMDAVIKDYGIGLFAVEDKESHQWIGFIGLNYIPETSDYPFKELPLYEIGWRL
                     LPEFWGKGLATEGAKATLKLAEEHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELP
                     NLSKYHLLKRQVRYYINLRK"
     gene            complement(11924..12223)
                     /locus_tag="RFE25_002288"
     CDS             complement(11924..12223)
                     /locus_tag="RFE25_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817324.1"
                     /translation="MHEQDFRILEGQDITLPELGRELENITGHTIADSTGEIKRVIAH
                     LPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK"
     gene            complement(12361..12756)
                     /locus_tag="RFE25_002289"
     CDS             complement(12361..12756)
                     /locus_tag="RFE25_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817325.1"
                     /translation="MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDK
                     KEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKDKEASQDKQSK
                     DQTKSSDKDNHKKPTSTDKDQKANDKHQS"
     gene            complement(12823..13266)
                     /locus_tag="RFE25_002290"
     CDS             complement(12823..13266)
                     /locus_tag="RFE25_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2817326.1"
                     /translation="MRTLNKDEHNYIKQIANIHETLLSQAESNYKCTKLSIALRYEMI
                     CSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIA
                     LEKWAKTMNAKRISSTIHKNNLPMISLNKDLGYQVSHVKMYKDID"
BASE COUNT         4605 a         2317 c         1926 g         4551 t
ORIGIN      
        1 ttaaaataac ctagattctt atttatattt ttaattaaag caaacctaac catttccaat
       61 aagtcatact aaaaactatc actagaatat accctacaat tgtcaatggt atacctgcct
      121 tcaagaaatc tttaaccgta aaagtaccag tgccataagc caacatattt tgaggtgcac
      181 taacaggtaa taagaaacca aaactaataa caaattgttg aattaaaaca aatcctatag
      241 actggtctcc taagtgtaac gtagaggtta gcgaaataaa aacaggtatt aacgctgatg
      301 ataaacttgt tgcactcgca aagcccaaat gaatcaatat attaaaaagc gtgataagtg
      361 caattgtcgc gataataggt aaatgtttta aacctaaaac accaaaagtt tgatcactta
      421 accattgagc tgcacctgtt ttcaaaagaa cgttccctag tgaaatacct acaccaaaca
      481 cgataattgt tccccatggt attttatttt caacatgttt ccatgtcatg acaccaattt
      541 tcggcattaa cataacacct aaagcaataa tagtaatgga tgcagagtca atcggatgta
      601 atactttttc agttgaccaa aacagtaata ataacatcga tataacaatt aaacgccatt
      661 cacgtgggct aacggggcca agtttatgca attcttcttt tattaaatct ttaccatctt
      721 ctattgtatt aatttctgga ggcatcactt taatcatgat gaaatataaa gctacggaca
      781 taactatgga ccaaggcgct gcatataaga accactcgcc ccatgaaaca tcaaatccta
      841 attgatggtt tataaaatta atcgctacga tattttgtgc tgccgccgtt ttgataccaa
      901 tattccaaat tgacacagct tgtactgaag taattattaa taaagacgct aacttgctat
      961 ctttggaaac tttaaatgcc gcaatcatac ccagcaagat tggtacaact gcccctgctc
     1021 tagctgttgc agaaggaacg aaaaatgcaa gtacaattga aacgataatt gctccaataa
     1081 ctatatttct agttttatta ccaacaattg ataacactaa aagagctagt cttttatgca
     1141 aattcgtttc ttgcatagca gcagccaaaa ataatgcagc tgcaacgaga gctacagctg
     1201 aagttgcata tccactaaac gctaatgata atgcatgatt agttcctaga aggtcacttc
     1261 cagctaaaat agcactgcca cttttcggat tacctagctt ctcccctaaa ttttgaaccg
     1321 ggctaaatcc taaaagtaat atcattaagc caataattaa agttgctgac accggatatg
     1381 atacagcttc cgttacccac ataataactg caaaagctaa aatagctagt actgccttag
     1441 ccattatcgg cagacttgaa ggtgccggga gtaatagtac aactataagt attataaaac
     1501 tcatgacaat ccaaaatggc ttgtattgct tttttgtctt ttctttcttt tgttgttcat
     1561 gttccactac atgtttttct tctgacataa cagtcacccc tttgtttaat cttaatttaa
     1621 ttataacaat tttttaaaac atacattttt aatttatgca aaatacacaa ttttatcgaa
     1681 atattttgta aataatattg ctaggtgatg agttatctcg gttaattaca aaacgatatc
     1741 taagtttaaa tattagatca taaaaaaact atctactgaa tatcctcata gcatcatttt
     1801 tctaagcaaa agttaaactt agttagataa aatgcaaatg agattattgt agatagtctc
     1861 tttttaatat ttaaaaatga ttaatgccat aaacataaat aattccaaag aatgccgcgc
     1921 cactaagcac tgttaatata agacttagta acaatgtgcg tttataatgt ttaataaatg
     1981 ctatgaacaa aatgactaca ttatacgcaa agaaaagtcc gaataatgtc attgttattt
     2041 tcaaatcaga atagaaaata tttaatagta atacaatgac tgcataaatt aaatacggaa
     2101 taactataaa tttgcgttca aatcttaatt gttcgaaacg tttatcttcg tttgtcatga
     2161 tatgctcctt tatgatttaa aagtaaataa gtttacggaa tatcttgtcc gataatagcg
     2221 gtgtaaatgt caaaccacga ctgatcatct aaattaagtt gtagcccttc gattgcttga
     2281 tcaatacgct ttaactgact tgttccaagt atcggcatga tactatgcgg tatttttact
     2341 aaccatgcta tcatcacagc tgtgtcactc acaccatatt tgtcagctat tgattgaaca
     2401 actttcataa tacgttgcgc tttaatatct tccttgtcga aaattttacc gcctgcaaaa
     2461 ggactccaag ccataatttg aacatggttt tgatacattg aatccattgt tccatcttgt
     2521 aaactatcaa cgtgatatgg cgataattct aattgattga tgctaatatg tagtctttct
     2581 ttcataatat attgatttaa caattggtat tgtgaatgat taaaattcga caccccgaat
     2641 gacttcaact taccttgttt aacaagttta gttaatgcat cagcaacttg ttctggatcc
     2701 atcaatggtg aaggacgatg aatgagtaga ctatctaaat aatctacatt caaattgatt
     2761 aatgactgtt caacagattt cacgatgtgc ttactactca aatcataacg atgtccattt
     2821 gtaaaatcaa attgcttaga aggcaaaatg ataccacatt tcgtaacaat ttgaatttta
     2881 tttcttaatt cgggtgataa atccaaagca ttaccaaaca gtgattcaca ttgataatcc
     2941 ccataaatat cagcatgatc catcgttgta attccacgtt caactaattc atttataaaa
     3001 taatttaact ctttcgcagt catcttccat tcatttgcac gccaaaaacc ttgtacaagc
     3061 ctagaaaaat gaacatagtg attaatcatt atttgttcca tatctcatcc actccatccc
     3121 tcaatgtcac aaaatattca caataaaagt attaagaaat taatgtgcta tttccgttaa
     3181 attgaaacaa cacattttct gatttacgta aattgtagca tatccaattg attacgtatg
     3241 tgatttgtat ctaaagtttc accaataata acaatcgtta atggtaattg catgccaatt
     3301 attccatagt ctggtaaacc atatgcatat tgaaattcat aaattgcatt tggttgattt
     3361 ctaaatgaca cataaccttt caaacgtaga acagattccg gtaatttcat tataaattga
     3421 taaaacaatt gacgatcaat cggacctgta aacgtgtaag tcatactttt aatcccatga
     3481 tgatggtgat gatgagacga tatctctctg tctttaacag ttaagtccaa ttcttccaac
     3541 gaaacttttc cataggttgt tttataagtt ggaatacttg cacaaatcat acctaattgc
     3601 ttatcaattt tctcaagact gtcatcagtt ataagatcaa ttttattaat aataatcatg
     3661 tcacttagtt tcaactgatc ttccatcagc gaaactgtat tttcggtata ttgatgacgt
     3721 tctaaaaatc gagtcgcatc taatacacca taaataatcg gcttttcaaa gaaattaacg
     3781 atttgcggat cttgacatgc aactagtaat tccaaaggat gcgcaatgcc tgtcgcttct
     3841 atgatgacat gattaacgtc cccttttaaa gcaatggctt ttagttcata gacaagttct
     3901 tgtttaagat cgcaacaaac acaaccatta atcaatgaat ggacttcaat ttcatttgaa
     3961 atactattgc tatcaatatc aaaagtaccg aattcattca tgatgatttt aattttctca
     4021 tcatttttta ataattcact aatataatgt gtcagtaacg tggttttacc actacccaaa
     4081 aatccgttaa ttatggatat tcttattttt tcatctttat tatttttcat tttatattct
     4141 cttttctatt acagttattt ttaaaaatga taacatatat attaaattat ctttttgctt
     4201 gatttaatca aaaatatctt ctaaacttta aacatacttt aattttagca tggcattgaa
     4261 tcaaagaaag ttgtgaatta ataaacaatc aactttttaa tgattaccaa tccgaaaaga
     4321 gaaaaaaacg gatagtatgt ctggaggaga actttaatgt ctgatcaaca taatttaaaa
     4381 gaacagctat gctttagttt gtacaatgct caaagacaag ttaatcgcta ctactctaac
     4441 aaagttttta agaagtacaa tctaacatac ccacaatttc ttgtcttaac aattttatgg
     4501 gatgaatctc ctgtaaacgt caagaaagtc gtaactgaat tagcactcga tactggtaca
     4561 gtatcaccat tattaaaacg aatggaacaa gtagacttaa ttaagcgtga acgttccgaa
     4621 gtcgatcaac gtgaagtatt tattcacttg actgacaaaa gtgaaactat tagaccagaa
     4681 ttaagtaatg catctgacaa agtcgcttca gcttcttctt tatctcaaga tgaagttaaa
     4741 gaacttaatc gcttattagg taaagtcatt catgcatttg atgaaacaaa ggaaaaataa
     4801 ttaacttttg tcatgacaat taaagtaatg tttagaattt attaagaata gaaaaacaat
     4861 tagcacgcgt aagcttgtta gttaaaaaac tgcttgaaag gtttcttagc ctatcaagca
     4921 gtttttttat gcattatatt gaatcatatt ccataaagca ccttgattag cgagtaattg
     4981 ttgatagttt cccttttcaa ctattttacc atttatcatc acaatgatgg tctcaaaacg
     5041 tgacaataaa gttaaatcgt gtgtagcaac aattaatgtt tctgcatgtg cttcaattaa
     5101 atccataact tttaaactat tttgtttatc taatgcagtt gttggttcat ctaaaatcca
     5161 tgttgatgca gtatctttta ataacatcct cgtaatcgct aaacgctgaa tttctccgcc
     5221 agataatgta tgaccatcta agtcaatttg acgttctagt gccaaatgtt ctaaatctaa
     5281 ttgcttaaat attgcttgca ccgcttcatc tttttcatcg gtaaataaat tttgacgtat
     5341 tgtaccatca aataattgtt gagattgtag caagacattt aacgattcaa acttatcttt
     5401 gtcatctatt tcaaacatat ccatattttc gaaacgaaca gagccactat ctaattgata
     5461 taaccctgcc ataatttgta gtaatgtact ttttcctgaa cctgaaggac ccacaatcgc
     5521 aatcttttcg cctctattaa cattaaaatt aatatccgac aacacatacg tttgctgatt
     5581 ccaatactta aaactagcat ccttaacttc ataaatgttc gttgcatcat acttatcatt
     5641 aagacgtttt tttccattag tagaaggtac agatatcact tcattaatat cgtgcaatgc
     5701 ttggtcagta tccgctttat aatacgcgac atttgtcatt ggtacagctt gttcaaataa
     5761 agttaagatc attaaaacta tactcgtcat ataaataata tttagttggc ctgcattaat
     5821 ttgaattaat cctagaacta aactaccaaa aatcgaaagc atagcaataa tatttaatat
     5881 aaaatcataa atcgttaaaa agcgttgctc tttaagttgt aatttatcaa aatgatttaa
     5941 tttagccatc aaattatctc gataatgatt aatttgatta aatcgacgta gttcatccat
     6001 accagcttta taatcataaa aatgatttaa aaatcgggcc tgttcattag ctgcatgttt
     6061 ctttaaagta cgtgcttttt ttgagcttaa ccaaggaaca atgagtaaag taaacaacat
     6121 gctaaccata atcaatagcg catggccgat tgaaatgaac gccaaaacta tgactgtaac
     6181 tagcgctgtc aaaccgataa cgactggtgg ataataaaca cgtaaatata tattttgtaa
     6241 tgcctcaaca cgactaatca tacgtgaaat taaatcacta gaactcagtt tacggtaaac
     6301 attaggaatg acatttacta atttaccgaa aaactgtacc cgaatatcac gtagcattgt
     6361 aaatgtagct ttatgagaaa taaggcgctc tacgtatcga gtaatagctc ttaaaaaccc
     6421 aaacaatttt actgtaacga ctaaaatcat cagagcgtat agtggcgcac caagtgcact
     6481 ttgtgtcacc atataaccac ttaagaaaaa catggcgagc gcaactaaac ttccacaaac
     6541 accaacaact atagctaaca ataaatcctt atctacttga aattttagtc gtgttttcat
     6601 aagtcatcac cattttctgt tatatttact gaaatattgc gatcatcagc aatcagtctt
     6661 ccattttcta tatacaagcg tcgttgtaaa tggcgaattg tattatctct atgtgcaatg
     6721 acaatcatcg ttgtatcttt aaaatgttga aacagaacgt tctgaatcat gtgttctgtt
     6781 tgaatatcta aaccagttgc aggctcatca aatataacga gatctggctt cataactaaa
     6841 agacggcaaa gttctatgcg tctcatctgt ccaccagata acatttcgcc tccttcacct
     6901 attattgtgt taatgccttt tgtgaaagat tgcactttgt ctaataaacc tacttcgtct
     6961 agcacttctt caatagtatt attttctata tctttaaaca tcgtaatatt ctcttttata
     7021 gaagcactga aaatatatgg ctgttgacta agtattccta tatttaaatc acgctggttt
     7081 gtacttatag tacctattgt tggctgataa acacctgcaa taagatgtgt caaagtggat
     7141 ttacctgccc cgcttggacc tacaagtgca atttgatcac ctttaaatat ttccaaattt
     7201 aaatcattta ataccaatct atcagaatca tcatatcgaa atgatatgtc tgttaactga
     7261 ataaatggct tttggttttc ctcatacttt aatagaaatt cattattata gttcggttgt
     7321 tctaaaaact caaacacaac gtcactggca ccttcacttt gttttccagt atggaacgct
     7381 tgccctaagt ccttaattgc attataaaat tcaggcgcta aaataatcgc aattgccgca
     7441 gttttaaaat caatattatg aaatactact aagcttagcg ttgcttccaa tgcaaccaat
     7501 ccaataccta acatacttat aaattcgagc attaatcccg ataaaaaagc actgcgtaaa
     7561 atgcgcattg ttaaagttct aaactgagta ctatcgtcgt aaatatgctt ctctgtttgc
     7621 tctgtacgat taaatagctt taacgtcact aaacctttag caatatttaa aaaccgttga
     7681 ctaaattgat tcaaataagt catttgatct tttgactcat ctcgcgtttt caaaccgaaa
     7741 ataatataaa acaaaggaat aaatggtgca gttattaaca taattaatgc ggtattgaaa
     7801 tggatgaaaa acattgcaat gattatgatg agcggaacca tcattgattt gaacacttga
     7861 ggcaaataac tcttataaaa aggtgctaaa ccatcaatgt tttctgtgag tatagtcatt
     7921 tgttcaccga ttggatgacc attattttta taaataaccc gctgtctaag catatgctta
     7981 actttaaatg ctaatgtatc acctaaccat tgatttagaa attgcacagt tgctcttaaa
     8041 agtaaaacac ctaataaaat aaataataca atccataaac cttgaaattg atgtcttata
     8101 attttagcta aaaaatctgc tattaaaata ttttgcgtta taacgagtat gccgagacca
     8161 gtactgacca agaacatgag taccggaaaa attttatatt gaaacagtat tgttgttaat
     8221 tttttcacaa ttatatcacc taaacctatt ataaaaggtt ttccttaaaa tcaaattaaa
     8281 tagctcaata aaatattgta gttttacatg taaaagaaaa tgaatatata catctttagt
     8341 ctagtattat aactataact agcatgtctt taaatgaata tgctatcatg atatggtaat
     8401 tttgatattt aaataaatta aattgagtaa tgaaagtggg tacattatgt ttatcattga
     8461 attaataaaa ggtattatct taggggtcgt cgaaggatta acagaatttg cacctgtttc
     8521 ctctactgga catatgattc tagttgatga tatgtggtta aaatcatctg aatttttagg
     8581 ttctcaatca gcatttacat ttaaaatcgt catccaatta ggatccgtct ttgcagcagc
     8641 atgggtattc cgcgaacgct tcttagagat tttacatatt ggtaaacaca aacatgttga
     8701 aggagaaaac gatcaacaaa gacgttcaaa gccaagacgt ttaaatttat tacatgtatt
     8761 agtgggtatg gtgccagcag gtattttagg cttactattt gatgatttca tcgaagaaca
     8821 tttatttagt gtgccaactg ttatgattgg cttattcgta ggtgctatct atatgattat
     8881 tgctgataag tattcagtta aagttaaaaa cccacaaaca gtggatcaaa tcaattattt
     8941 ccaagcgttt gtaattggta tctctcaagc agtagctatg tggcctggtt tcagccgttc
     9001 aggctcaaca atttcaactg gggtattaat gaaattaaat cataaagcag catcggactt
     9061 cacatttatt atggctgttc caattatgtt agcagctagt ggtttatctt tattaaaaca
     9121 ttatcaagat attcagattg ctgatatacc tttttatatt ttaggctttt tagctgcatt
     9181 tactgttgga ctaattgcaa tcaaaacatt cttgcatcta attaacaaaa tcaaactaat
     9241 tccatttgcc atttacagaa ttgtattagt aatctttatt gctatacttt acttcggatt
     9301 tggcattggt aaaggtattt aatttccttt taaaatatag actgtcaatt aaggaaccac
     9361 ttgattggca gtttttattg tcttctttta aaaaacatct gaaatactta atagtgattc
     9421 actactatca tcgtttatat tgatgtatca tagggtatgt aaaattaata aagtaattat
     9481 ggaggcaaga tctatggata agaaaaaagt catcaaattt atgattaatg tattaccaat
     9541 tgtattggta ccgttaattg ttgaacgtaa acgtatcaaa caacatccgg acgtacaaaa
     9601 agttacagat gctacaagta aagttgcttc aaaaacatct gcagcaatca gtaacacagc
     9661 gagtgatgtt aaagaatatg tcggcgataa aaaacaagat tttgaaaata aacgtgaact
     9721 taaaaagttt gctagagaac atgatcctgc ctatattgag aaaaaaggcg aaaaattagc
     9781 taaacaaaat cgtaaagacg ctgataaaat gaataaaata cttcaaaaaa atatcgaaaa
     9841 gcgtcataaa gaagagcaaa aagcccgcga aaagaatgaa atacaacgta ttaaagatat
     9901 gaaaaaatca caaaaatacg aagaaaaagc aggcttaaca cctaataaat tagatgagaa
     9961 aactgagaaa aaaggcgata aactagctga aaaaaatcgc aaagaaatcg ctaaaatgaa
    10021 taaaaagtta caaaaaaata ttgaaaaacg acacaaagaa gaacaaaaac gccaacaaga
    10081 agctgataaa gcacgcatca agtcatttaa aaaatataaa gattatgttg ccaaaagcgc
    10141 ctctcaacaa aataaagaaa acaatacaga ggcataattg tgacacatat tattattgat
    10201 ggagatgctt gtcctgttgt tgattctatt atagatttaa caactgagac aggcattttt
    10261 gtgacaatta ttcggagctt cagccatttt tcgaaccaat tatatcctcc acatgtatca
    10321 acattatatg ttgatgatgg accagatgca gttgattaca aaattgttca attatcaacg
    10381 aaggatgata tcgtagtcac tcaagattat ggactcgcaa gtttattagt cgacaaagtc
    10441 ttaattgtca tgcatcataa tgggaagata tacaattcca aaaatattca acaactatta
    10501 gataaacgat atataaatgc acaaattaga aaacaaggtg gtcgccacaa aggtccccca
    10561 ccttttacaa agcaagatca aaaagtgttt gaacaatcac tattaaaagt cattcatcga
    10621 attaaggagc tggattaaca tgaaacgaat cgcagtttat tgtggtgcaa gcaaaggtca
    10681 tgacccttca tatgtacaaa aagcatacga tttaggtaaa tattttgctg aacaaggtta
    10741 tgaattagta tttggtgcag ggtcaattgg cattatgggt gccattcaag atggtgtatt
    10801 aaatcatggc ggcaaagcta ttggcgtcat gcctaaaatg ttagatgaac atgaaatcac
    10861 aagccaacgt ttaactgaat taattttagt tgattctatg catgaacgta aaaataaaat
    10921 ggcagaactt gcagatgcat ttgtcatggc tcctggtggc gcaggttcac tagaagaatt
    10981 tttcgaaatg tatagttggg ctcaaatagg tatccatgaa aagcctattg ccatttataa
    11041 tattaatggc tttttcaatc cactacaaac aatgattgac catatgattg aggaaggttt
    11101 tattgatcct aagtatcgtg ctcttgcacc gttatgcgac actaaggaat cattaataga
    11161 atcaatatta aatttcaaac ctctgggtac tcgttcatac gattaatcat tctaaggtta
    11221 aaaaataaac aaacacccct aatattgtta tcatcagcta aacaatgtta ggggtgtttg
    11281 ttacgattat gtataaattt ttcactttcg aagattaatg taatagcgca cttgcctttt
    11341 taataaatga tacttactta gattgggtaa ttcgaaatga tcatacactg tcatgccaat
    11401 tttttccatt acacgttgtg aggctttatt tgcttctgct gtaaaactat agacatcgta
    11461 tatttgatgt tcttctgcta acttcaacgt tgcctttgcg ccttcagttg ctaatccttt
    11521 tccccaaaat tcaggcaaca agcgccaacc tatttcataa agcggtaatt ctttaaatgg
    11581 ataatcgctt gtttctggaa tataattcaa acctataaag cctatccatt gatgggactc
    11641 tttatcttct acagcaaata atccaatgcc ataatcttta ataaccgcat ccatagttct
    11701 catatctaat tctgaacgac gataactcaa taaacttgga aaatatttac gtacgtcata
    11761 attcgcattc attttttgaa aaggtaacag atcatcttca tgccagtctc ttaatattaa
    11821 acgctctgtt tcacaataaa tcatcgattg acactcctat ataatttctc aataaaaaac
    11881 acaaaatcga tattttgatc aactttgcgt tttagatagc agtttatttt gatttagaaa
    11941 tataacttat aagttcaaca tgaactggca cttcttttaa acgtgctcta tctgatttca
    12001 gcgcagtaaa agttgcatct ataaaatctt gttgatggtt taaacgatat gtagcaacaa
    12061 aagtatctgt atcggactca aagtttggta aatgtgcaat tacacgctta atttcgccag
    12121 tagaatcagc aatcgtatgt cctgtaatat tttctaattc tctacctaat tctggcaaag
    12181 taatatcttg accctctaaa attctaaaat cttgttcatg catgccgttt ctctccttta
    12241 ttaattacgt tgtctatttt tacgttctgt ttcaatcatg accacatttt aattaataca
    12301 tacccttaaa ataaggttta aaacgctgta cctttcatct ataacaagta agcaatacga
    12361 ttatgattgg tgtttgtcat tagctttttg atctttatct gttgatgtag gctttttgtg
    12421 attatcttta tccgatgact tagtttgatc ttttgattgc ttatcttgtg atgcctcttt
    12481 atctttatct ttgtctttat ttttgtcttc gtctttttta tcatccttgt tatcttcttt
    12541 tgaaggtttt aaatctttca cttctttttc aaggtctttt tgcttatctg ctaatttttc
    12601 tttttcttgt tgaagctttt cttttttgtc ttttaattct ttattttctt tttgtaaatt
    12661 atcgatatcc ttttccagag tggctttctc ttgactttta ccacaacctg ttaaaaatag
    12721 catgaccgcc ataatactga tgattaattt cttcatataa aactccttaa cgtcattaaa
    12781 tcttttttaa ttttaacatg aattagcaac ataatcctaa ttctaatcaa tatctttata
    12841 cattttcaca tgactcactt gataacctaa atctttattc aaagatatca ttggcaaatt
    12901 atttttatga attgtactgc ttattcgctt tgcattcata gtttttgccc atttttcaag
    12961 cgcaatcttc agttgcgtag ctattcccag tttgcgaaat tgtggttcaa catatagcag
    13021 ttcaatgtta accatacttt tttcattact aaaatgtccc caaataaacg ctattaattg
    13081 accttcattt tcatatatat aaattttatc atttgtatgt tctaatcttg aacatatcat
    13141 ctcgtaccta agagcaatac tcagtttagt acatttatag ttggattctg cttgcgacaa
    13201 taatgtctcg tgtatattag ctatttgctt gatataatta tgttcatctt tattaagtgt
    13261 cctcattttc ctctccaata ttaatcgtta tatttatgcg tttaatatga tatgattgac
    13321 tttattaata ctataaaatc atttccattt taattaggaa ttaaacattt ttaaaggagc
    13381 gcttaagtaa caatgaaaa
//
LOCUS       DAPDIM010000070        13390 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000070 DAPDIM010000000
VERSION     DAPDIM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13390
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.070"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(131..328)
                     /locus_tag="RFE25_002291"
     CDS             complement(131..328)
                     /locus_tag="RFE25_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817327.1"
                     /translation="MNCYDEIFNTIKKLIENKEISSYQINKDTGISYGNINAMRRGER
                     RIENLSLKNAKILYEYAKKVL"
     gene            complement(821..2161)
                     /gene="glnA"
                     /locus_tag="RFE25_002292"
     CDS             complement(821..2161)
                     /gene="glnA"
                     /locus_tag="RFE25_002292"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HDU2817328.1"
                     /translation="MPKRTFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQL
                     EKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWVIFPWTAGQGKVARLICDVYKTD
                     GTPFEGDPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFD
                     LAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKL
                     VVKTIARKHNLHATFMPKPLFGVNGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQF
                     TAGVLKNARGFTAVCNPLVNSYKRLVPGYEAPCYIAWSGKNRSPLIRVPSSRGLSTRI
                     EVRSVDPAANPYMALAAILEAGLDGIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPS
                     TLYTALKAMRENEVIKKALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY"
     gene            complement(2180..2548)
                     /locus_tag="RFE25_002293"
     CDS             complement(2180..2548)
                     /locus_tag="RFE25_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDU2817329.1"
                     /translation="MISNDAIRRNMAVFSMSVVSKLTDLTPRQIRYYETHELIKPERT
                     EGQKRLFSLNDLERLLEIKSLLEKGFNIKGIKQIIYDSQEHLTTDEQEIRKKMIVDAT
                     QKPIGETLPINRGDLSRFIK"
     gene            complement(2791..4029)
                     /locus_tag="RFE25_002294"
     CDS             complement(2791..4029)
                     /locus_tag="RFE25_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDU2817330.1"
                     /translation="MKDISKIVADVESTLAPYFKEIEETAYINQEKVLNAFHHVKATE
                     SDLQGSTGYGYDDFGRDHLEEIYAQAFKAEDAIVRPQIISGTHAITIALQSLLKHGDE
                     LIYITGSPYDTLLEVIGVNGNGIESLMEHGVSYKDIALKEGKIDIESVLDGVSERTKV
                     IAIQRSKGYDQRPSIPLDEIEKVITRLKNVHPNILIFVDNCYGEFVERREPIECGADL
                     IAGSLIKNPGGGLAKIGGYIAGRKDLIERCGYRLTAPGIGKEAGASLNALLEMYQGFF
                     LAPHVVSQSLKGALFTSLFLEKMNMNTTPKYYEKRTDLIQTVKFETKEQMISFCQSIQ
                     HASPINAHFSPEPSYMPGYEDDVIMAAGTFIQGSSIELSADGPIRPPYEAYVQGGLTY
                     EHVKIAVTRAVNQLKEQGLI"
     gene            complement(4048..5286)
                     /gene="hflX"
                     /locus_tag="RFE25_002295"
     CDS             complement(4048..5286)
                     /gene="hflX"
                     /locus_tag="RFE25_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDU2817331.1"
                     /translation="MAQQQIHDTKNKLEKAVLVGVHAQDDKQFNFESTMEELSSLSET
                     CQLEVLGQITQNRDRVDRKYYVGKGKIEEIQAFIEFKDIDVVITNDELTTAQSKSLNE
                     ALGVKIIDRTQLILEIFALRARSKEGKLQVELAQLDYLLPRLQGHGKSLSRLGGGIGT
                     RGPGETKLEMDRRHIRTRMNEIKHQLRTVEEHRERYRNKRNQNQVFQVALVGYTNAGK
                     SSWFNVLANEETYEKDQLFATLDPKTRQIQINDGFNLIISDTVGFIQKLPTTLIAAFK
                     STLEEAKGADLLVHVVDSSHPEYRTQYDTVNDLIKQLDMSHISQIVIFNKKDLCDHAS
                     NRPASDLPNVFVSSKNDGDKLLVKTLFIDEIKRQLTYYDETIATNNADRLYFLKQHTL
                     VTELKYDEIENVYRIKGFKK"
     gene            5398..5874
                     /locus_tag="RFE25_002296"
     CDS             5398..5874
                     /locus_tag="RFE25_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDU2817332.1"
                     /translation="METIYDFVVETNKGVTYKLDAYKGDVMLIVNTASECGFTSQFEG
                     LQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEH
                     QLPLFRYLTAAQHGFFNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL"
     gene            complement(6096..6329)
                     /gene="hfq"
                     /locus_tag="RFE25_002297"
     CDS             complement(6096..6329)
                     /gene="hfq"
                     /locus_tag="RFE25_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDU2817333.1"
                     /translation="MIANENIQDKALENFKANQTEVTVFFLNGFQMKGVIEEYDKYVV
                     SLNSQGKQHLIYKHAISTYTVETEGQASTESEE"
     gene            complement(6344..7279)
                     /gene="miaA"
                     /locus_tag="RFE25_002298"
     CDS             complement(6344..7279)
                     /gene="miaA"
                     /locus_tag="RFE25_002298"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDU2817334.1"
                     /translation="MNKNKPFIVVIVGPTASGKTELSIELAKRINSEIISGDSMQVYK
                     HMNIGTAKVTPEEMDGIPHHLIDILNPDDTFSAYEFKRLAEDLITDITNRGKVPIIAG
                     GTGLYIQSLIYNYELEDETVTPAQLSIVKQKLSALEHLDNQQLHDYLAQFDAVSAENI
                     HPNNRQRVLRAIEYYLKTKKLLSNRKKVQQFTENYDTLLLGIEMSRKTLYSRINKRVD
                     IMLDHGLFREVQQLVEQGYESCQSMQAIGYKELIPVINGQMIYEDAVNDLKQHSRQYA
                     KRQMTWFKNKMSVHWLDKENMSLQMMLDEITTQIK"
     gene            complement(7297..8211)
                     /locus_tag="RFE25_002299"
     CDS             complement(7297..8211)
                     /locus_tag="RFE25_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2817335.1"
                     /translation="MTEKQFKLTVQDNTNIEVKVNFTDVDSKGIIHIFHGMAEHMERY
                     DKLAHALSKHGFDVIRHNHRGHGINIDESTRGHYDDMKRVIGDAFEVAQTVRGNVDKP
                     YIIIGHSMGSVIARLFVETYPQYVDGLILSGTGMYSLWKGLPTVKVLQLITKIYGAEK
                     RVEWVNQLVSNSFNKKIRPLRTQSDWISSNPIEVDNFIKDPYSGFNVSNQLLYQTAYY
                     MLHTSQLKNMKMLNHAMPILLVSGYDDSLGDYGKGILKLANIYRKAGIKNVKVNLYHH
                     KRHEVLFEKDHDKIWEDLFKWLNQFYKK"
     gene            complement(8361..10034)
                     /locus_tag="RFE25_002300"
     CDS             complement(8361..10034)
                     /locus_tag="RFE25_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase/oxidase"
                     /protein_id="HDU2817336.1"
                     /translation="MALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMK
                     VALVEMQDFAQGTSSRSTKLVHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEW
                     MLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKETLAKEPLVKKEGLKGG
                     GYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNEN
                     YTIKAKKVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEK
                     DGRMIFAIPREGKAYVGTTDTFYDNIKSSPLTTQEDRDYLIDAINYMFPSVNVTDEDI
                     ESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQDIVDLVSK
                     RLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASK
                     YGSNVDELFNIAQTSQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIK
                     DVLDYKDAVIDIMADMLDYSPAQIEAYTEEVEQAIKEAQHGNNQPAVKE"
     gene            complement(10192..11688)
                     /gene="glpK"
                     /locus_tag="RFE25_002301"
     CDS             complement(10192..11688)
                     /gene="glpK"
                     /locus_tag="RFE25_002301"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDU2817337.1"
                     /translation="MEKYILSIDQGTTSSRAILFNQKGEIAGVAQREFKQYFPQSGWV
                     EHDANEIWTSVLAVMTEVINENDVRADQIAGIGITNQRETTVVWDKHTGRPIYHAIVW
                     QSRQTQSICSELKQQGYEQTFRDKTGLLLDPYFAGTKVKWILDNVEGAREKAENGDLL
                     FGTIDTWLVWKLSGKAAHITDYSNASRTLMFNIHDLEWDDELLELLTVPKNMLPEVKP
                     SSEIYGKTIDYHFYGQEVPIAGVAGDQQAALFGQACFECGDVKNTYGTGGFMLMNTGD
                     KAVKSESGLLTTIAYGIDGKVNYALEGSIFVSGSAIQWLRDGLRMINSAPQSESYATR
                     VDSTEGVYVVPAFVGLGTPYWDSEARGAIFGLTRGTEKEHFIRATLESLCYQTRDVME
                     AMSKDSGIDVQSLRVDGGAVKNNFIMQFQADIVNTSVERPEIQETTALGAAFLAGLAV
                     GFWESKDDIAKNWKLEEKFDPKMDEGEREKLYRGWKKAVEATQVFKTE"
     gene            complement(11817..12635)
                     /locus_tag="RFE25_002302"
     CDS             complement(11817..12635)
                     /locus_tag="RFE25_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDU2817338.1"
                     /translation="MNVYLAEFLGTAILILFGGGVCANVNLKRSAANGADWIVITAGW
                     GLAVTMGVFAVGQFSGAHLNPAVSLALALDGSFDWSLVPGYIVAQMLGAIVGATIVWL
                     MYLPHWKATEEAGAKLGVFSTAPAIKNYFANFLSEIIGTMALTLGILFIGVNKIADGL
                     NPLIVGALIVAIGLSLGGATGYAINPARDLGPRIAHAILPIAGKGGSNWSYAIVPILG
                     PIAGGLLGAVVYAVFYKHTFNIGCAIAIVVVIITLILGYILNKSSKKGDIESIY"
     gene            complement(13110..>13390)
                     /locus_tag="RFE25_002303"
     CDS             complement(13110..>13390)
                     /locus_tag="RFE25_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HDU2817339.1"
                     /translation="VIKKAKSLNTLTIFRVFIIDSQALKRSIDLIKKVEPDFVEVLPG
                     VASKAIHHIQKETNTQVIAGGLINTIDEVNEAVKNGAKYVTTSYDKLW"
BASE COUNT         4134 a         2564 c         1839 g         4853 t
ORIGIN      
        1 ttttaaaaaa cataagtaaa tcactaaaca tgatttcttt cacttttaga aaacttttaa
       61 tactataaaa acacccactc agtcactagt ttgggcagtt attgtatgcc tattgaactc
      121 aatgcttata ttacaatacc tttttcgcat attcatataa gatctttgca ttctttaagc
      181 ttaaattttc tattcttctt tccccacggc gcatagcatt aatattaccg taacttatcc
      241 cagtatcttt attaatttga taacttgata tctctttgtt ttctatcaat tttttgattg
      301 tattgaatat ttcatcatag caattcataa attagatgag gcgaaatttt taatttttta
      361 gaatatcaat agtagtataa ctaaaatgaa aataccgatc gataaacaaa aagatatttt
      421 ttgttttgtt tctcttttca tatagtatta cccccttaat aatgcgtagt aaggtccctc
      481 ttttcggggt cttaccttag aacgttctgc aaatgaattc gatgagaagt aatatgaata
      541 tggctatttt caagtaatac tcaacgtttt cgcgacgttc ttttatcgcc tcatctcatc
      601 acctccaaat atattaaaat tcatgtgaac taaaatataa aatggtcttc cccagcttta
      661 aaaaaataaa tacataaaac atttacttga ccaaaacttg accaaatcca ttttttaaca
      721 aaagtggtca agtgaaatcc catctttcca aatcaaaaaa gagctaaagc aaaacgctct
      781 agcccttgat attactgatt tcccatcatt gtttagcgta ttaatattgc ttcatgtact
      841 gatctctttc ccattcagat acttgagttc tgtagtaatc ccattcaatt gattttgaat
      901 taataaattg attatagata tgatttccta aagctttttt aataacttca ttttcacgca
      961 ttgcttttaa tgcagtataa agtgttgaag gtaagtcttg aatgcctact gcttcacgtt
     1021 cttcacggtt catttcgtaa atattttggt taactggttc tggaactttt aatttatttt
     1081 taataccatc tagtccagct tctaagattg cagctaacgc catgtatggg tttgcagctg
     1141 gatctactga acgtacttcg atacgagtag ataatcctct tgaagatggt acacggatta
     1201 atggtgaacg gtttttacca ctccatgcaa tataacatgg tgcttcataa ccaggtacta
     1261 aacgtttata tgagtttact aacgggttac atacagcagt aaatccgcgt gcatttttaa
     1321 gcacacctgc tgtaaattga tatgcagttt ccgttaagcc catttcagta tttggatcaa
     1381 agaatgcatt ttctttacct ttgaataatg aaacgttaaa gtgcataccg ctaccattca
     1441 caccgaataa tggtttaggc ataaatgttg cgtgtaaatt atgtttacgt gcgattgttt
     1501 taacaaccaa tttaaatgtt tggatattat cacatgctgt aacagcatct gcatatttaa
     1561 agtcaatttc atgttgacca ggggcaactt catggtgact agcttcaata tcgaagccca
     1621 tatcctctaa ttctaaaaca atatcacgac gacagttttc acctaaatct gtaggtgcta
     1681 aatcgaaata tccaccatca tcattaagtt ctaaagttgg ttcccctttt tcatccaact
     1741 taaacaagaa gaattctggt tcaggcccta ggttaaagtc tgtgaagcct aaatcttcca
     1801 tttcttttaa tacacgtttt aagtttgcac gaggatcccc ttcaaatggt gttccatctg
     1861 ttttatatac atcacaaatt aaacgtgcaa ctttaccttg tccagcagtc catgggaaga
     1921 ttacccaagt atctaaatct ggatgtaagt acatatctga ttcttcgata cgtacgaaac
     1981 cttcgataga agaaccgtca aacatcattt cgttatcaag tactttttct aattggctta
     2041 caggcacttc aacattttta attgttccta aaatatcagt gaattgtaat cttaaatatc
     2101 ttacattttc ctcttctgca aatttacgaa tgtcttcttt agtgaaagta cgttttggca
     2161 ttttaaaatc ctccaaattt tatttaataa atcgggataa atcaccacga tttattggca
     2221 aagtttctcc aataggcttt tgcgtggcat ctacaatcat cttttttctt atctcttgtt
     2281 catctgttgt taaatgctct tgtgagtcat aaatgatttg tttaatccct ttgatattaa
     2341 atcctttttc taataatgat ttaatttcta gtaatctttc caaatcattg agtgagaaca
     2401 gacgtttttg accttctgtt ctttcaggtt tgatgagttc atgtgtttca tagtaacgta
     2461 tttgccttgg cgttaaatcc gttaacttac ttactacact catagagaag acagccatat
     2521 ttcgtctgat tgcatcattc gatatcattg ttcctctcct ctacttttga acttgttaat
     2581 aacttatcat aattttttta ggatttcaaa aatatgtcag gttttctaac ataaagctta
     2641 aaacattgat ataactgcga tttcgacttc taaaacgaca taaaacaatc tacagctaaa
     2701 atattttttc aatttttaaa aataatctga taaatctccg caaaaaattt cacccaagac
     2761 acattatcat ttagggtgaa atttaatcta ttatataagt ccttgttctt tcaactgatt
     2821 aacagctctt gtcacagcaa ttttaacgtg ttcatatgtt aatcctcctt gaacatatgc
     2881 ttcataagga ggacgaatag gtccatctgc agataattca atcgatgaac cttgaataaa
     2941 cgtaccagct gccataataa catcatcttc gtaaccaggc atataactag gttctggact
     3001 aaaatgtgca ttaattgggg atgcgtgttg aatactttga caaaatgaaa tcatttgttc
     3061 tttcgtttca aatttaactg tttgaattaa atcagttcgt ttttcgtagt acttcggcgt
     3121 tgtgttcata ttcatttttt ctaaaaataa actagtaaac aatgcacctt taagactctg
     3181 actgacaacg tgtggtgcta aaaagaaacc ttgatacatt tcaagcaatg catttaatga
     3241 tgcacccgct tctttaccaa taccaggtgc tgtcaatcta taaccacatc gttcaattaa
     3301 atcttttcta ccagcaatgt atccaccaat cttagctaaa ccaccgccag ggtttttaat
     3361 taatgatcct gctattaaat cggcaccaca ttctataggt tcacgtcttt caacaaattc
     3421 cccataacag ttatccacaa atattaaaat attaggatgc acgtttttca acctagtaat
     3481 taccttttca atttcatcta gcggaattga aggtctttga tcatagcctt tcgaacgttg
     3541 aatcgctatt actttggtgc gctcagaaac cccatctaac acactttcaa tatcgatctt
     3601 accttcttta agtgcaatat ctttatacga tacgccgtgc tccattaaac tttcaatacc
     3661 atttccgttt acgccaatga cttcaagtaa agtgtcatat ggactacccg ttatataaat
     3721 taattcatca ccatgtttta ataaactttg taatgcaata gtaatcgcat gcgtacctga
     3781 aataatttgc ggacgaacaa ttgcatcttc tgctttaaat gcctgcgcat atatttcttc
     3841 taaatgatca cgtccaaagt catcataccc gtatcctgtt gatccttgta gatcactttc
     3901 ggttgctttg acatgatgaa atgcatttaa tactttttct tgattaatat atgctgtttc
     3961 ttcaatttct ttaaaatatg gtgctaacgt tgattcgacg tcagctacta tcttacttat
     4021 atctttcatt tgaatttcgt ccttttatta ttttttaaat ccttttatac gataaacatt
     4081 ttcaatttca tcatatttaa gttcagtcac taatgtatgt tgttttagaa aatataatcg
     4141 atctgcatta ttcgtcgcaa ttgtctcatc ataataagtt aattgccttt tgatttcatc
     4201 aataaataac gtcttaacaa gtaatttatc accatcattt ttagaagaaa caaaaacatt
     4261 aggcaaatca cttgctggac gatttgatgc atgatcacat aagtcctttt tattaaaaat
     4321 aactatttga gaaatatgac tcatatctaa ttgtttgatt aaatcattaa ctgtgtcata
     4381 ctgcgtacgg tattcaggat ggctactatc tacgacatgt actaataaat ctgcaccttt
     4441 agcctcttct aaagttgatt taaaagctgc aattaacgtc gtaggtagtt tctgtataaa
     4501 accaacagta tctgaaataa ttaaattaaa tccatcattt atttgaattt gtcgtgtttt
     4561 aggatctaac gttgcaaata attgatcttt ttcatacgtc tcttcatttg ctaaaacatt
     4621 aaaccatgat gatttaccag catttgtata accaactaaa gctacttgaa acacctgatt
     4681 ttgatttctt ttatttcgat atctttcgcg atgttcttct accgtccgca attgatgttt
     4741 aatttcattc atacgagttc gaatatgtct gcgatccatc tctaacttcg tttcaccagg
     4801 gcctctagtt ccaataccgc cacctaaacg agaaagactt ttaccatggc cttgcaatct
     4861 aggtaataaa taatcaagtt gtgctagctc tacttgcaat ttaccttctt tacttcttgc
     4921 tcttaatgca aatatttcaa gaatcaactg agttctatca ataattttta cacctaaagc
     4981 ttcatttagt gatttggatt gtgcagtcgt taattcatca tttgtgatga ctacatcaat
     5041 atctttgaac tcaataaatg cttgaatttc ttcaatttta cctttaccaa cataatattt
     5101 gcgatctaca cgatctctgt tttgagtaat ttgacccaac acttcaagtt ggcaagtctc
     5161 tgataaagat gataattcct ccattgtaga ctcaaaatta aattgcttat catcttgagc
     5221 atgtacaccg actaagacag ctttttctag tttattttta gtatcatgaa tttgttgctg
     5281 agccatgtta tacatctcct taataaaatc ctactcaaag tattctatca tagagtttta
     5341 gtaaagacta ttacacgatt ttatggtaca ttttaagtaa atcgaaagga tgattcaatg
     5401 gagacaattt atgattttgt agtagaaaca aataaaggtg ttacttacaa attagatgca
     5461 tataagggtg acgttatgct aattgttaat acagctagcg aatgtggctt tacttcacaa
     5521 tttgaaggtt tgcaatcatt atacgagaaa tacaaagatc aagggtttgt aattctaggt
     5581 ttcccttgta atcaatttgg tggtcaagaa cctggatcag gcgaagaagc agctcaaaac
     5641 tgtaaattaa actatggtgt taccttccct atgcatcaaa aaatagacgt aaaaggggaa
     5701 catcaattac ctttatttag atatttgact gcggcacaac acggattctt taatgagaaa
     5761 atcaaatgga atttcactaa gtttttagtg gatcgcgaag gtaacgttgt taaacgattt
     5821 gcacctcaaa aaaaacctgt tcaaatcgaa agagaaatag aaaaattatt ataaaatata
     5881 ctagctcata gcaaataaaa cgcttcatat aaagtcgtat catatattga ctcgaccttt
     5941 atatgaagcg tttttattac aaacattcct ctattgtatc ttgtcatttg aacatcattt
     6001 aattgatgtc acatatgact ttatttctat atctatttat catacttcaa acgttatgta
     6061 cacgagtcat taaatcgtgc ccatatgatt acaacttatt cttcactttc agtagatgct
     6121 tgaccttcag tttctactgt ataagtgctg atcgcatgtt tgtaaatcaa gtgttgtttg
     6181 ccttgagaat ttaagcttac gacatacttg tcgtattctt caataacacc tttcatttgg
     6241 aaaccgttta gaaagaatac agttacttca gtttggtttg ctttaaaatt ctctagtgct
     6301 ttgtcttgga tgttttcgtt tgcaatcatc tgtcggactc cttttactta atctgggttg
     6361 taatctcatc taacatcatt tgaagtgaca tattttcttt atctaaccaa tgaacactca
     6421 ttttattctt gaaccatgtc atttgtcgtt ttgcatattg gcgtgaatgt tgctttaaat
     6481 cattgacagc atcttcataa atcatttgtc cgttaatcac aggtattaat tctttatatc
     6541 caatagcttg catactttgg caagattcat agccttgttc aacaagttgt tgcacttctc
     6601 taaataatcc gtgatccaac ataatatcaa cacgtttatt tattcttgaa tataatgttt
     6661 tacgcgacat ttcaatccct aataataatg tatcataatt ttcagtaaat tgttgcactt
     6721 tcttgcgatt actcaaaagt ttttttgttt ttaaataata ttcaatagcg cgcaacactc
     6781 tttggcggtt gttagggtga atattttctg cagaaaccgc atcaaattga gctaaataat
     6841 cgtgtagttg ctgattatct aaatgttcta atgcagataa cttttgttta actatggata
     6901 attgtgcagg tgtaactgtt tcatcttcta attcataatt atatattaat gattgaatat
     6961 ataagcctgt tccacctgct atgattggaa ctttacctct attcgttata tcagtaatta
     7021 aatcttctgc taatcgcttg aattcatatg ctgaaaatgt atcatcagga ttcaagatat
     7081 caattaaatg atgtggaata ccatccattt cttcaggtgt tacttttgca gttccaatat
     7141 tcatatgttt gtaaacttgc atagaatcac cgcttatgat ttcactattg atacgcttcg
     7201 cgagttctat gctaagctct gttttacctg aagcagttgg ccccacaatt actacaataa
     7261 aaggcttatt tttattcata tttaattcca ctttctttat tttttataaa attgattcaa
     7321 ccatttaaac aagtcttccc aaattttgtc atgatctttt tcaaataata cttcatgacg
     7381 tttatgatga taaagattca ctttaacatt tttaatgcca gcttttctat atatattcgc
     7441 caattttaaa atccctttac cataatcacc taaagaatcg tcatatcctg aaactaataa
     7501 tataggcatg gcatgattta acattttcat attttttaat tgtgatgtat gtagcatata
     7561 ataggctgtt tgatataata attgatttga cacattaaat ccactatatg gatctttaat
     7621 aaagttatct acttcaattg gattactaga aatccaatca ctttgtgtac gtaatggacg
     7681 tattttttta ttaaaactat ttgatactaa ctggttaacc cattcaactc gtttctcagc
     7741 accataaatt tttgtaatca gttgtaacac tttaacggtt ggtaaacctt tccataatga
     7801 atacatacca gtaccactta aaattagacc atcaacatat tgcggatatg tttctacaaa
     7861 caatctagct ataacggatc ccattgaatg tccgattata atgtatggtt tatcaacatt
     7921 gcctctcact gtttgcgcta cttcaaaggc atcaccgata actcgtttca tatcatcgta
     7981 atgccctctt gttgattcat caatattaat accatgtcct cgatgattat gacgtatcac
     8041 atcgaagcca tgctttgaaa gtgcatgtgc taatttatcg taacgttcca tatgttcagc
     8101 cataccatga aatatatgaa taattccttt tgaatctaca tctgtaaaat tcactttaac
     8161 ttcaatattc gtattatctt gtacagttaa tttaaattgt ttttcagtca tcatctcaca
     8221 cctttaataa caacgttttt atattcgctt ttattattat catacattta gtgatgcata
     8281 gtttcaattg actaatgtat ctcgtataaa aaaactgatg cccttaaaac aggacaccag
     8341 tttatgattg tacaaattaa ttattcttta actgctggtt gattatttcc atgttgcgct
     8401 tctttaattg cttgctcaac ttcttcagta tatgcttcaa tttgagctgg agagtaatca
     8461 agcatatctg ccataatatc gatgacagca tctttataat ctaatacatc tttaatattg
     8521 aaatacattt taccagaacg acgaactaag aaatcgttag gtttgtatac catttcttgt
     8581 tgaatactat aaacaagttc tacataaatt tctaatggta acttgctatc atggtattga
     8641 gatgtttgcg caatgttgaa caattcatca acatttgaac catatttaga tgctaaacgt
     8701 cttgcaacat cttcatcaat gccgaatcct ttagctacat ctactttttg ctctacaaac
     8761 gcatcaaagt tcttgctacc acctacatcg ccacctgaaa ttgccagacc ttttgtatta
     8821 catggactaa atgttaaacc gtagtctttt ttcaagcgtt tagatactaa atcaacaatg
     8881 tcttgagcca tgtgacgata gcctgttaat ttaccacctg caatagttaa taaacctgat
     8941 ttaccttccc aaatttcatc cttacgagag atttcagaag ggtctttgcc ttcttcgtaa
     9001 attaatggtc taattcctgc ccatgttgat tcaatatctt catctgtaac attaacacta
     9061 gggaacatgt aattaatcgc atcgattaaa tagtctctgt cttcttgtgt agttaatggt
     9121 gaagatttga tattgtcata gaatgtatct gtagtaccta catacgcttt tccttcacgt
     9181 ggaattgcaa aaatcattct tccatctttt tcagtatcaa agtatactgc ttgacctaat
     9241 gggaattttg attgatcaat aacaacatgt acacctttag ttaaacgtaa ttttttatta
     9301 ttgcgtgcat aatcaccact tctaacatca tcaacccatg ggcctgctgc attaaccact
     9361 tttttagcct taattgtata attttcatta gttaatttat ctataacttt aacaccattt
     9421 acttgttgat ttttatcata agtgaagtgt tcagatttag tatagttgat aatttctgcg
     9481 cctttttcag cagcacgctt cataacttca atagttaaac gcgcatcgtc agtacgatat
     9541 tcaacatagt aaccgccgcc ttttagacct tcttttttaa ctaatggttc tttagctaaa
     9601 gtttcttttt tagataacat ttttttacgt tcagacttct taacacctgc taaacgatca
     9661 tacattccta aaccaattga tgttgagaat ttaccaaatg ttccaccttt atgcattggt
     9721 aaaagcatcc actctggagt cgtaacatga ggcccatttt cataaacaat cgcacgttct
     9781 ttaccagttt cggcaactac tccaatttgg aattgtttta agtaacgtaa accaccatgg
     9841 actaattttg tagatcttga gcttgttcct tgtgcaaagt cttgcatttc aactaatgca
     9901 actttcattc ctctttcact cgcgtctagt gcaatacctg cacctgtaat accgccacca
     9961 ataattacta aatcatattc atcatttctt aaattctttt taatatgttc tctcttaaaa
    10021 gtagacaatg ccattccaaa acgcctccta aaaaatgtaa aaacgagaga cttgtcccac
    10081 ataaacaatc cttcaattgt acatgttcga acaaatctct cgtttctcga ttcaaatatt
    10141 aacttaaatt gattgtatca caatgtttat acaaaagtct aatctacaag tttattctgt
    10201 tttaaaaact tgtgttgctt caacagcttt tttccaacct ctatataatt tttctctttc
    10261 gccttcatcc attttcggat cgaatttttc ttctaatttc cagtttttag cgatatcatc
    10321 tttactctcc cagaatccaa ctgctaaacc tgctaaaaat gcagcaccta aagctgtagt
    10381 ttcttgaatt tcaggtcttt caacagaagt attaacaatg tctgcttgga actgcataat
    10441 aaagttattt ttaactgcac caccatcgac acgtaaactt tggacatcaa taccagagtc
    10501 ttttgacatt gcttccataa cgtcacgagt ttggtaacat aatgattcta aagttgcacg
    10561 gataaagtgc tctttttcag ttccacgtgt taaaccgaaa atcgcaccac gtgcttcaga
    10621 atcccaatat ggtgttccta aacctacaaa agctggaaca acataaacac cctcagtaga
    10681 gtcaactcgt gtcgcataac tttctgattg tggtgctgaa ttaatcattc ttaatccatc
    10741 acgtaaccat tggattgctg aacccgaaac aaagatggaa ccttcaagcg cataatttac
    10801 ttttccatca ataccataag caattgttgt taataaacca ctttcagatt taaccgcttt
    10861 gtcacctgta ttcattaaca tgaagccacc agttccatat gtgtttttca cgtcaccaca
    10921 ttcgaagcaa gcttgtccaa ataatgctgc ttgttgatca ccagctacac cagcgattgg
    10981 tacttcttga ccatagaagt ggtaatcaat tgtcttacca tatatttcac ttgaaggttt
    11041 aacttctggc aacatatttt taggtactgt aagtagttct aataactcat cgtcccattc
    11101 taaatcatgg atattaaaca ttaatgtacg actcgcattt gaataatcag taatatgcgc
    11161 agcttttcct gataatttcc atactaacca agtatcaatc gttccaaata atagatcgcc
    11221 attttctgct ttttctcgtg caccttcaac attgtctaga atccatttaa cttttgtacc
    11281 tgcaaaatac ggatctaaaa gtaatcctgt cttatctcta aatgtttgtt catatccttg
    11341 ttgttttaat tctgaacaaa ttgattgtgt ttgacgtgat tgccaaacaa ttgcgtgata
    11401 aattgggcgg ccagtatgtt tgtcccaaac aaccgttgtt tcacgttggt ttgtaatacc
    11461 gattcctgca atttgatcag ctctaacatc attttcatta attacttccg tcattacagc
    11521 taacacagat gtccaaattt catttgcatc atgttcaacc caacctgatt gtggaaaata
    11581 ttgcttaaac tcacgttgtg ctacccctgc aatttcccct ttttgattga ataaaatcgc
    11641 tcttgagctt gttgttcctt ggtctataga taaaatatat ttttccatta gtagtatctc
    11701 ctttattaaa aaataatcgc taacccattg tacaaaatct gttaaatttt ggcgaaaaaa
    11761 tagcataatc catgaatcaa acatgttaaa ttatgctatt tacgtttctt tttattttag
    11821 taaattgatt cgatatcacc tttttttgat gatttattta aaatgtaacc taaaatcaaa
    11881 gtaataataa ctacaacaat tgcaattgca caaccaatat taaatgtatg tttataaaat
    11941 acagcgtata ccactgcacc taataaacca ccggcaattg gtcctaagat aggaacgatt
    12001 gcatatgacc aatttgaacc acctttacca gctattggta aaatcgcatg tgcaattctc
    12061 ggacctaaat cacgtgctgg gttgattgca taaccagtag caccgcctaa acttaatccg
    12121 attgcaacaa ttaatgctcc gacaattaaa ggatttaaac catcggcaat tttgtttaca
    12181 ccgataaata aaatacctaa agttaatgcc attgttccga taatctcact taaaaagttg
    12241 gcaaagtaat tcttaatagc cggtgctgta gagaaaacac ctaatttcgc gccagcttct
    12301 tctgtcgctt tccaatgtgg caagtacatt aaccatacaa ttgttgctcc gacaattgca
    12361 cctaacattt gagcaacaat ataaccagga actaatgacc aatcaaaact tccgtctaat
    12421 gcaagagcta aagacaccgc tgggtttaaa tgtgcacctg agaattgacc gacagcaaac
    12481 acacccattg taaccgctaa tccccatcca gctgtgatga caatccaatc agcaccattc
    12541 gcagcacttc tctttaaatt gacattggca caaacgccac caccaaaaag gattaagatt
    12601 gcagttccta ggaattctgc taaatataca ttcatattaa atgtcctccc aaaaagacaa
    12661 agagattcct acactagcag tttggctcgt agaaatctcc cgtctctatt ctatgtatta
    12721 acttttatta tatttgttat gatactatcg atatgaaagc gttgtcaatg gtttttgtaa
    12781 aaattttgtc aaatttaatt tttcaagtct ttataaaagt agtttaattt gaaaactaga
    12841 aatatcaatc cgcactaatt tatttatgac gccattttgt ttaattgaca ttcttcagcc
    12901 atatttttta tgactagttg cattttttac taataaacac ctctaaaact ttaatgattt
    12961 taatcgtttt agaggtgcta attatgttat ttaattattc tttgtatgat accttaaata
    13021 ccttattaca tatcccatat gaaaacggct tttttattat gttatatgac taaatctcgt
    13081 gaaaaatgaa atttttgcag acttatgatt taccaaagtt tatcataact agttgttaca
    13141 tatttcgctc catttttaac agcttcattg acttcatcta ttgtattaat taggccacct
    13201 gcaatgactt gtgtgtttgt ttctttctga atatgatgaa tcgctttact cgcaacacct
    13261 ggaagtactt caacaaaatc aggttccact ttttttatca aatctatact gcgtttcaat
    13321 gcttgactat caataataaa tactctaaaa atcgttaaag tatttaatga tttagctttt
    13381 tttattactt
//
LOCUS       DAPDIM010000071        12966 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000071 DAPDIM010000000
VERSION     DAPDIM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 12966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12966
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.071"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            260..1243
                     /locus_tag="RFE25_002304"
     CDS             260..1243
                     /locus_tag="RFE25_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDU2817340.1"
                     /translation="MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSST
                     VAPIVEKLNEKWAQDHSDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQ
                     DKNIKYKEFKIAQDGVTVAVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKI
                     NAVSPNSSHGTYDFFENEVMNKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQN
                     KDKLKEVKIKDENGKATEPTKKTIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVL
                     EDKGKAAEEAGYVAAPEKTYKSQLDDLKAFIDKNQKSDDKKSDDKKSEDKK"
     gene            1434..2360
                     /gene="pstC"
                     /locus_tag="RFE25_002305"
     CDS             1434..2360
                     /gene="pstC"
                     /locus_tag="RFE25_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDU2817341.1"
                     /translation="MTSSTNVKALIEKNINKKGKHNDKIIPVILAAISAISILTTLGI
                     LITLLLETITFFTRIPITEFLFSTTWNPTGSDPKFGIWALIIGTLKITVIATIFAVPV
                     GLGAAIYLSEYASDRARRIIKPILEILAGIPTIVFGFFALTFVTPVLRSFISGLGEFN
                     AISPGLVVGIMIVPLITSLSEDAMASVPNKIREGAYGLGATKLEVATKVVLPAATSGI
                     VASIVLAISRAIGETMIVSLAAGSSPTASLSLTSSIQTMTGYIVEIATGDATFGSNIY
                     YSIYAVGFTLFIFTLIMNLLSQWISKRFREEY"
     gene            2362..3279
                     /gene="pstA"
                     /locus_tag="RFE25_002306"
     CDS             2362..3279
                     /gene="pstA"
                     /locus_tag="RFE25_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDU2817342.1"
                     /translation="METTDNNRQSLVDQQLVQKHLSSRTVKNKVFKLIFLACTLLGLV
                     VLIALLTQTLIKGVSHLNLQFFTNFSSSTPSMAGVKGALIGSLWLMLSIIPLSIILGI
                     GTAIYLEEYAKNNKFTQFVKISISNLAGVPSVVFGLLGYTLFVGGAGIEALKMGNSIL
                     AAALTMTLLILPIIIVSSQEAIRAVPNSVREASYGLGANKWQTIRRVVLPAALPGILT
                     GFILSLSRALGETAPLVLIGIPTILLATPRSILDQFSALPIQIFTWAKMPQEEFQNVA
                     SAGIIVLLVILILMNGVAIILRNKFSKKF"
     gene            3326..4177
                     /locus_tag="RFE25_002307"
     CDS             3326..4177
                     /locus_tag="RFE25_002307"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDU2817343.1"
                     /translation="MAQTLAQTKQISQSHTFDVSQSHHKTPDDTNSHSVIYSTQNLDL
                     WYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRD
                     QDIFDQKYSKEQLRTNVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSL
                     RGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRV
                     EELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTED
                     YISGRFG"
     gene            4184..4825
                     /gene="phoU"
                     /locus_tag="RFE25_002308"
     CDS             4184..4825
                     /gene="phoU"
                     /locus_tag="RFE25_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDU2817344.1"
                     /translation="MAIIRQRYQEQLDDLIKELRRLGANVYVSIENGIKSLSIDDRGF
                     ARQTVKNDKHINQLNYDINERVIMLITKQQPIASDLRMMISSLKIASDLERIGDNASS
                     IANIRLRTKITDDYVLTRLKTMGKLAMLMLKDLDQAFKKKDTVLIREIIERDEDIDDL
                     YSHIINATYLIDNDPFVAAQAHLAARHLERIGDHIINIAESVYFYLTGTHYEQ"
     gene            complement(4965..6779)
                     /gene="pepF"
                     /locus_tag="RFE25_002309"
     CDS             complement(4965..6779)
                     /gene="pepF"
                     /locus_tag="RFE25_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDU2817345.1"
                     /translation="MSQGLPLREDVPVSETWDLVDLFKDDQQYYESIDALVQQANQFH
                     HTYATTLNSIEQINTALAELENILIALDRLSNYAELRLSVDTSNIEAQVLSAKLSTTY
                     GKIVSQLSFVESEILELPEEILQQLEESCPYQHYIKQLIKQKPFQLSASVEQVLATLS
                     PTLNSPYDLYGTTKMLDITFDSFEHDGTTYPVDYATFENDYEDNKDPEFRRKSFKSFS
                     DGIRKYQHTTAATYNMQVQQEKIEADLRGFESVIDYLLHSQEVTRDMFDRQIDMIMRD
                     LAPVMQKYAKLLQRIHGLDNMRFEDLKISVDPDYEPEISIEDSKNYIFGALSVLGDDY
                     TNMLREAYDQRWIDFAQNKGKDTGAFCASPYFTHSYVFISWTGKMAEAFVLAHELGHA
                     GHFTLAQKHQPYLESEASMYFVEAPSTMNEMLMANYLFNTSDNPRFKRWVIGSILSRT
                     YYHNMVTHLLEAAYQREVYHKVDQGESLNAPTLNEIMLNVYKQFFGDAVDMTEGAELT
                     WMRQPHYYMGLYSYTYSAGLTIGTVVSQKIKNEGQPAVDAWLETLKKGGSVSPVELAN
                     IAGVDITTEQPLKSTIQYISDLVDEVEKLTDEIEQANN"
     gene            6984..7328
                     /locus_tag="RFE25_002310"
     CDS             6984..7328
                     /locus_tag="RFE25_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817346.1"
                     /translation="MTLFDMPNYLWITTLIMILLTIFCCLVLNKWFVSAVITFVILGV
                     LAFFIPNFQDIKYQPLLGYAAFLAIMSLLISFLLWYFTRNWRKERKARKLEKQIEKYG
                     YEGAELRRKDKK"
     gene            7276..7461
                     /locus_tag="RFE25_002311"
     CDS             7276..7461
                     /locus_tag="RFE25_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817347.1"
                     /translation="MKNTAMRALNFAVKIKNNIRQLYAQNHRLLSYTAVTIISKEMEY
                     SAIVVFVLTFLYFTWLT"
     gene            7632..8618
                     /locus_tag="RFE25_002312"
     CDS             7632..8618
                     /locus_tag="RFE25_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817348.1"
                     /translation="MFIIKSMLYRLMQMIVVLFVISTLTFILMKLSPGNPVDKILHLD
                     VAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEPVTQILFNYAPI
                     TLLISFSTLVVSLCISIPLGIIAAKRFHKWTDKVIRVISTLSISLPAFFIGIILLFIV
                     TNLMNIDSVILSQFILPVITLSLGMCAYIIRLVRSNLLMLLQSNIVQASRLRGMNERY
                     ILIHDLLKPTILPIIPLLGISLGSLIGGTVVIENLFDIPGIGYLLMDSIKSRDYPVIQ
                     GCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKNKTNTPLISESSDRHA"
     gene            8611..9441
                     /locus_tag="RFE25_002313"
     CDS             8611..9441
                     /locus_tag="RFE25_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817349.1"
                     /translation="MHKIFSKNNLIFFVFVAFIFVVIVLQFFVSSENATKVNLSQTFE
                     PISWLHLLGTDDYGRDLFTRIIIGARSTLFVTVLTLIAIVVIGVTLGLFAGYKKGWIE
                     RLVLRFIDVGLSIPEFIIMIALASFFQPSLWNLVISITVIKWMNYTRLTRSIVNSEMN
                     KPYIKMAQLFHVPTRTILIRHLTPKIIPAIIVLMVVDFGKIILYISSLSFIGLGAQPP
                     TPEWGAMLQQGRDFISSHPIMLIAPASVIAITILIFNLTGDALRDRLLKQRGEYDESH
                     "
     gene            9428..10201
                     /locus_tag="RFE25_002314"
     CDS             9428..10201
                     /locus_tag="RFE25_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817350.1"
                     /translation="MSLIDIQNLTIKNTCEKYLIKGIDLKIFSQQINALIGESGAGKS
                     LIAKALLEYLPFDLSCTYDSYQFDGENISRLSQYYGHTIGYISQNYAESFNDHTKLGK
                     QLTAIYRKHYKSSKEEALSKIDKALSWVNLQSKDILNKYSFQLSGGQLERVYIASVLM
                     LEPKLIIADEPVASLDALNGNQVMDLLQHIVLEHGQTLFIITHNLSHVLKYCQYIYVL
                     KEGQIIERGNINHFKYEHLHPYTERLIKYRTQLKRDYYD"
     gene            10194..10895
                     /locus_tag="RFE25_002315"
     CDS             10194..10895
                     /locus_tag="RFE25_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817351.1"
                     /translation="MIELKHVTFGYNKKQMVLQDINITIPDGENVGILGESGCGKSTL
                     ASLVLGLFKPVKGEIYLSDNAVLTIFQHPLTSFNPDWTIETSLKEALYYYRGLTDNTA
                     QDQLLLQHLSTFELNAQLLTKLPSEVSGGQLQRFNVMRSLLAQPRVLICDEITSNLDV
                     IAEQNVINILKAQTITNLNHFIVISHDLSVLQRLVNRIIVLKDGMIVDDFAIEELFNV
                     DRHPYTKELVQTFSY"
     gene            11019..11492
                     /locus_tag="RFE25_002316"
     CDS             11019..11492
                     /locus_tag="RFE25_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HDU2817352.1"
                     /translation="MGLLDIASIRSIERGFNYYQSECVINLKSFSETQHEAEVKGSGN
                     KVYRCYIDMEHPRKSKCNCPHADGRRVICKHMIALLFTASPEAANKHIMMLNEVEEDY
                     QLRRNMWIDSLKEMINDMSEEELRDAYLNMLIEHGEMAELFGLDEEEEMFEDEFY"
     gene            complement(11540..12307)
                     /locus_tag="RFE25_002317"
     CDS             complement(11540..12307)
                     /locus_tag="RFE25_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDU2817353.1"
                     /translation="MRFVFDIDGTLCFDGRLIDQTIIDTLLQLQHDGHELIFASARPI
                     RDLLPVLPSVFHQHTLIGANGAMISQQSKISVIKPIHTDTYHHILKIIQKYELDYIID
                     DDWNYAAQLDAENAIFERLDPHKLASCIDVANIDTPIKIILLNIDPAQITTILDELNK
                     YHQELEMIHHSNEYNIDITAQNINKYTALQYIFDADVKYIAFGNDHNDIFMLQHASSG
                     YIIGPSEAYTHAILKLDKIKHINNNTQAICKVLKSYK"
     gene            complement(12537..>12966)
                     /locus_tag="RFE25_002318"
     CDS             complement(12537..>12966)
                     /locus_tag="RFE25_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001558444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817354.1"
                     /translation="NGISLIIQGFTAEFTISLISESNIHNNHEFAVNLFRYVIQEGGI
                     SFSTYLVCNFSIIMWLFFSCSLLKERKPVVRCLPLIISCLKLILILLFLLSILLVIYQ
                     TQSAQILFIFIDFLNFVALILVYLCTNPNNRGIDKIACVK"
BASE COUNT         4500 a         1898 c         2194 g         4374 t
ORIGIN      
        1 actgctgttt ttttagggat ttatgtccca gcctcatttt ttgtgtacat atttaaattt
       61 cgataatttt tcaggaagca ttttaatttt actaatgaag caatattttt tagattaaca
      121 aaaattaata tttacatttt cttaacaaat ttttatgtaa catttacagt ttctaaaaat
      181 gaggttaata attcaaggtt aagataaaga tgtaatcaat acaaatacta tttgttgttc
      241 atacagggag gatatttcaa tgaaaaaatg gcaatttgtt ggtactacag ctttaggtgc
      301 aacactatta ttaggtgctt gtggtggcgg taatggtggc agtggtaata gtgatttaaa
      361 aggggaagct aaaggtgatg gctcatcaac agtagcacca attgtggaga aattaaatga
      421 aaaatgggct caagatcact cggatgctaa aatctcagca ggacaagctg gtacaggtgc
      481 tggtttccaa aaattcattg caggagatat cgacttcgct gatgcttcta gaccaattaa
      541 agatgaagag aagcaaaaat tacaagataa gaatatcaaa tacaaagaat ttaaaattgc
      601 gcaagatggt gtaacggttg ctgtaaataa agaaaatgat tttgtagatg aattagacaa
      661 acagcaatta aaagcaattt attctggaaa agctaaaaca tggaaagatg ttaatagtaa
      721 atggccagat aaaaaaataa atgctgtatc accaaactca agtcatggta cttatgactt
      781 cttcgaaaat gaagtaatga ataaagaaga tattaaagca gaaaaaaatg ctgatacaaa
      841 tgctatcgtt tcttctgtaa cgaaaaacaa agagggaatc ggatactttg gatataactt
      901 ctacgtacaa aataaagata aattaaaaga agttaaaatc aaagatgaaa atggtaaagc
      961 aacagagcct acgaaaaaaa caattcaaga taactcttat gcattaagta gaccattatt
     1021 catttatgta aatgaaaaag cattgaaaga taataaagta atgtcagaat ttatcaaatt
     1081 cgtcttagaa gataaaggta aagcagctga agaagctgga tatgtagcag caccagagaa
     1141 aacatacaaa tcacaattag atgatttaaa agcatttatt gataaaaatc aaaaatcaga
     1201 cgacaagaaa tctgatgata aaaagtctga agacaaaaaa taataagacg caatttcaaa
     1261 tgtgtcttga aacatgattt tgatggtgaa tcattattta gagtacaaag cttgatttat
     1321 cgagacgctg attttgacat tcagttagtc tacaagctta tcaacttaaa atagtggttc
     1381 atcattattt tacaaatcta attattttgg gagtaataga aagaggtttg attatgactt
     1441 catctactaa tgttaaagct ttaatcgaaa aaaatattaa taaaaaaggg aagcataatg
     1501 acaaaattat accagttatt ttagccgcaa tttcagcgat ttccatttta acaacactag
     1561 gtatattaat cacattgctt ttagaaacca tcactttttt caccagaatt ccaataactg
     1621 aatttctatt ttctactact tggaatccta ccggttcaga ccctaagttt ggtatctggg
     1681 cattgataat agggacttta aaaatcacag ttattgcgac tatatttgca gttccagtcg
     1741 ggcttggtgc agcaatttat ttaagtgaat atgcaagtga ccgtgcacga cgcataatta
     1801 aaccgatatt agaaatttta gcaggaatac caacaattgt gtttggtttc tttgcattaa
     1861 cctttgttac accagtatta agatctttca tatcaggtct tggagagttt aatgctataa
     1921 gtcccggctt agttgtcggt attatgattg tccctctcat cacaagtttg agtgaggatg
     1981 caatggcatc tgtaccaaat aaaattcgag aaggtgccta tggacttgga gcaactaaat
     2041 tagaagtagc aactaaagtc gtacttcccg cagcaacatc aggtattgta gcttcaatcg
     2101 ttctcgcgat ttcaagagca attggagaaa cgatgattgt atcattagcg gcaggtagtt
     2161 cgccaacagc ttcattaagt ttaacaagtt cgattcaaac aatgactgga tatattgttg
     2221 agatagcgac aggtgatgca acatttggat caaatattta ttacagtatt tatgctgtag
     2281 ggttcacact atttatcttt accttaatca tgaatttact ttctcagtgg atttctaagc
     2341 gttttaggga ggagtattaa tatggaaacg acagataata atagacaatc actcgtcgat
     2401 caacaacttg tccaaaaaca tttatcatcc agaacggtta aaaataaagt gttcaaactc
     2461 atatttttag catgtacatt attaggactt gtcgtactta ttgcgttgtt aactcaaaca
     2521 ttgattaaag gggtaagtca tttaaattta cagtttttca ctaatttttc ttcttcaaca
     2581 ccatctatgg ctggcgttaa aggcgcgtta atcggttcac tttggttaat gttaagtatc
     2641 attccattat caatcatcct aggaataggt acagctatat acttagaaga atatgcgaaa
     2701 aacaacaaat ttactcagtt tgttaaaatc agtatttcca atttagctgg tgtaccatca
     2761 gttgtatttg ggttattagg ttacactttg ttcgttggtg gtgcggggat tgaagccttg
     2821 aaaatgggta acagtatatt ggcagcagcg ctaacaatga ccttactgat attaccaatt
     2881 attattgttt caagtcagga agcaattaga gctgtaccta actcagtacg cgaagcttct
     2941 tatggtttag gtgctaataa atggcaaacg ataagacgtg ttgtcttacc agcagcgtta
     3001 cctggtattt taactggatt cattttgtct ctttcaagag cactgggaga aacagcgcca
     3061 cttgtgctaa tcggtatacc gactatatta ttggcaacac ctagaagtat attggatcaa
     3121 ttttcagcat taccaatcca aatatttact tgggcgaaaa tgcctcaaga agaattccag
     3181 aatgttgcat cggcaggcat tatcgtttta ctagttatct taatcttaat gaatggcgtt
     3241 gcgattattt tacgtaacaa atttagtaaa aaattctaat ttaaacaatc aatctcattt
     3301 atctattaaa aagggagttt taaatatggc gcaaacactt gcacaaacta aacaaatatc
     3361 tcaaagtcat acgtttgatg tctcacaaag tcatcataaa acaccagatg atacaaactc
     3421 acattctgtt atatattcaa cacaaaattt agacttatgg tatggcgaaa atcatgcatt
     3481 acaaaatatt aatttagata tttatgaaaa ccaaattact gccattatag gtccatctgg
     3541 ttgtggcaaa tcaacatata ttaaaacttt gaatcgaatg gttgagttag taccttctgt
     3601 gaaaacagct ggtaaaatat tatatcgaga tcaagacatt tttgatcaaa aatattctaa
     3661 agaacaatta cgtacaaatg tgggcatggt ctttcaacaa cctaatccat ttccaaaatc
     3721 aatatacgat aatattactt acggtccaaa gattcacggt attaaaaata aaaaagttct
     3781 tgatgaaatc gttgagaaat cattacgtgg cgctgcaatt tgggatgaat taaaggatag
     3841 gttgcacaca aatgcatata gtttatccgg tgggcaacaa caacgtgttt gtatcgcgcg
     3901 ttgtttagca attgaacctg aagtcatttt aatggatgaa ccgacatcag cattagatcc
     3961 aatctcaaca ttaagagtag aagagttggt tcaagaacta aaagaaaagt atacaattat
     4021 tatggttaca cataatatgc aacaagcagc tcgtgtatca gataaaactg catttttctt
     4081 aaatggttat gtcaatgaat atgatgatac tgataaaatt ttctctaacc catcaaacaa
     4141 gaaaacagaa gattatattt caggaaggtt tggttgatat ataatggcaa taattagaca
     4201 gcgatatcag gagcaacttg atgatttaat aaaggaatta cgtcggttag gtgcaaatgt
     4261 ctatgtgagt attgaaaatg gtataaaatc attaagtatt gacgatagag gctttgcacg
     4321 acaaacagtt aaaaacgata aacatatcaa tcaattaaat tatgatatta atgagcgagt
     4381 tatcatgtta attacaaagc aacagcccat tgcgagtgat ttgcgtatga tgatttcttc
     4441 attaaaaatc gcctccgatt tagaaagaat aggagataat gcatcgagta ttgccaatat
     4501 tcgattgcgt acaaagatta cagatgatta tgtgttaacc cgtttaaaga caatgggtaa
     4561 attagctatg ttaatgttaa aggacttaga tcaagcattt aaaaagaaag ataccgtatt
     4621 aataagagaa ataattgagc gtgatgaaga tatcgatgac ttatatagtc atattattaa
     4681 cgcaacgtat cttattgata acgatccatt tgtcgctgca caagctcatt tagcagcaag
     4741 acatttagaa cgtattggtg atcatattat taacatcgct gaaagtgttt atttttattt
     4801 aacaggtaca cattacgaac aataacttaa agttattact ataaaatccc ttacgataaa
     4861 tatatatttc tatcattcat aaaccctcaa aaaaaccaag attctcacaa ttagtaatgt
     4921 gaaaatcttg gtttatattg ttctactata aattgtctcg catcttagtt atttgcttgc
     4981 tcaatttcat ctgttaattt ttcaacttca tcgactaaat cagaaatata ttgaattgta
     5041 gatttaagtg gctgttctgt agtaatgtct acacctgcaa tgtttgcaag ttcgacaggt
     5101 gatacactac cacctttttt caatgtttct aaccaagcat caacagctgg ttggccttca
     5161 tttttaatct tttgagaaac gacagttccg attgttaagc cagcagaata cgtatacgaa
     5221 tataatccca tatagtaatg aggttgacgc atccatgtta attcagcacc ctcagtcatg
     5281 tctactgcat ctccaaaaaa ttgtttataa acatttagca ttatttcatt taatgtcggc
     5341 gcatttaaag attcaccttg atctactttg tgatacactt cacgttgata agcagcttct
     5401 aataaatggg taaccatatt atgataatat gttctagata aaattgagcc aataacccaa
     5461 cgcttaaatc ttggattatc acttgtgtta aataaataat tggccatcaa catttcattc
     5521 attgtagaag gggcttcaac aaagtacatt gatgcttctg attcaagata tggttgatgt
     5581 ttttgagcta atgtaaaatg acctgcatga cctaattcat gtgctaagac aaatgcttca
     5641 gccattttac cagtccaaga aataaacaca tatgaatgtg taaagtatgg acttgcacaa
     5701 aatgcgcctg tatctttacc tttattttgt gcaaaatcaa tccatcgctg atcgtatgct
     5761 tcacgtaaca tgtttgtata gtcatcacct aaaacactta acgcaccgaa aatataattt
     5821 tttgagtctt caattgaaat ctctggttca taatcagggt ctacagaaat cttcaagtct
     5881 tcaaaacgca tgttatctaa tccgtgaata cgttgtaaaa gtttagcata tttctgcata
     5941 actggtgcca agtcacgcat aatcatatcg atttgacggt caaacatatc acgcgttact
     6001 tcttgactat gtaataaata atcgatgact gattcaaatc cacgtaaatc agcttcaatt
     6061 ttttcttgtt gtacttgcat attatatgta gccgcggtag tatgctgata ttttcgaatc
     6121 ccatcgctaa acgatttgaa acttttacgt ctaaactcag gatctttatt atcttcataa
     6181 tcattttcaa acgtagcata gtcgacaggg tacgttgtac catcatgttc aaatgaatcg
     6241 aatgtaatat ctagcatttt tgtcgtgccg tataaatcgt aaggactgtt tagcgtaggt
     6301 gataaagttg ctaatacttg ttctaccgac gcagataatt ggaatggctt ttgttttatt
     6361 aactgtttaa tatagtgttg atatggacat gattcttcta attgttgaag tatttcttct
     6421 ggtaattcaa gtatttctga ctctacaaat gataattggc taacaatttt accgtatgta
     6481 gtagataatt tagcgctcaa tacttgtgcc tcgatattac tagtatctac acttaaacgt
     6541 agttctgcat aattacttaa gcgatctaag gcaattaaaa tattttctaa ttcagctaaa
     6601 gcagtattaa tttgttcgat tgaatttaat gttgttgcat atgtatgatg aaattgattt
     6661 gcttgttgta ctagagcgtc aatactttca taatattgtt gatcatcttt aaataagtct
     6721 actaaatccc atgtttctga aacaggaaca tcttctctta aaggtaaacc ttgagacata
     6781 taatcactcc tttggtataa tacattcatt atacataatt ttgtctccta aacgataatg
     6841 ttacgatttc catgtcgcaa ggaacaatga tttttctaat agtagataga atattgcttg
     6901 aaactgactg ctattgttta agtttttaaa aatttataat aaaatgtata caaggaaagt
     6961 aatgaaataa aaggagaatg aatatgacat tattcgatat gcctaattat ttatggatca
     7021 caacattaat aatgatttta ttaacaatat tctgttgctt agttttaaat aaatggtttg
     7081 tatctgcagt aattacattt gttatattag gtgtgcttgc attttttatt ccaaattttc
     7141 aagatataaa atatcaacca ttattaggat acgctgcatt tttagcgatt atgagtttat
     7201 taattagttt tctattatgg tattttacta gaaattggcg taaagaaaga aaagcgcgta
     7261 aattagaaaa gcaaattgaa aaatacggct atgagggcgc tgaacttcgc cgtaaagata
     7321 aaaaataata ttcgacaact atatgcacaa aatcatcgac ttttaagtta cactgcagta
     7381 acaattattt cgaaagagat ggaatacagt gctatagttg tttttgtttt gactttttta
     7441 tattttacat ggttgacttg attcaaaata ttatatttta taatgatttt gttaaaaaat
     7501 taaatatact tcaatttctt tatggataat actataatga acgttggttc ttaatatgta
     7561 agttgcatat acatgcgcca ttctcatgta aaaagaaagt gttagtaact tacacaagga
     7621 gggggactat tatgttcata ataaagtcta tgttgtatag actgatgcaa atgatagttg
     7681 ttttatttgt tatttctaca cttacattca ttttaatgaa attatcacca ggcaatcctg
     7741 ttgataaaat attacatctt gatgtagcac aagtgtcgac ggaacaaata aatgcaacca
     7801 aagataaatt gggattaaat gattctttat tggtacagtg gtggcattgg atgaatcatt
     7861 tattacattt taatttagga aaaagttttg aatcaaaaga accggtaaca cagatattat
     7921 tcaactatgc acccataaca ttactcatat cattttcaac attagtagtg tcgttatgca
     7981 tatctatacc gctcggcatt atagcagcca aacgatttca taagtggacg gataaagtga
     8041 ttagagtgat ctcaacacta tcgattagtt taccagcgtt ctttatcggt attattttat
     8101 tatttattgt cacaaattta atgaatatag atagcgttat actaagtcag tttatattac
     8161 ctgtaatcac gctatcttta ggtatgtgtg catacatcat tcgtttagta cgttctaatt
     8221 tattgatgtt attgcaaagt aatatcgtac aagcatcaag attacgcggt atgaatgaac
     8281 gttatatttt aattcatgat ttactaaaac caacaatttt gccgattatc ccattactag
     8341 ggatttcact tggcagtcta ataggtggta ctgtagtgat tgaaaattta tttgatatac
     8401 ctggtattgg ttatctatta atggatagta ttaaatctcg agattatcct gttattcaag
     8461 gatgcgtgtt atttattggc ttcttcgttg ttattatcaa tacgattgct gatttattaa
     8521 cgttattact tgatccgaag cagcgtttac aattaggaaa tccaaaaaac aaaaccaata
     8581 caccattgat atcagaaagt agtgaccgtc atgcataaaa tattttcaaa gaataacctg
     8641 atattttttg tattcgttgc atttattttt gtggtaattg tactgcaatt ctttgtcagt
     8701 agtgaaaatg caaccaaagt caatttatca caaacttttg aacctattag ttggttgcat
     8761 ttattaggaa ctgatgatta tgggagagat ttatttaccc gaattattat cggtgcacgt
     8821 tcaacattgt ttgttactgt tttaacatta atagctatcg ttgtcatagg tgttacacta
     8881 ggtctatttg ccggatataa aaaagggtgg attgaacgat tagtgttaag gtttattgat
     8941 gttggtctaa gtattccaga atttatcatc atgattgctt tagcaagctt ttttcaacca
     9001 tctttgtgga atttagttat ctcaattaca gtaataaaat ggatgaatta cacaaggttg
     9061 actagaagta tagttaatag cgaaatgaat aagccttata taaaaatggc acaattattt
     9121 catgtaccta caagaacaat attaatacgt catttaacac ctaaaattat accggctatt
     9181 atcgttttga tggtcgttga tttcggtaaa atcattttat atataagttc actatcattt
     9241 attgggttag gtgcacaacc gccaacacca gagtggggcg ctatgttgca acaaggtcgt
     9301 gattttattt cgtctcatcc aattatgttg attgcacctg cttcagtcat tgctataact
     9361 attttaattt ttaatttaac cggagatgcg ctaagagata gattgctaaa acaacgaggt
     9421 gaatatgatg agtctcattg atatacaaaa tttaacaata aagaatactt gtgagaaata
     9481 tcttattaaa gggattgatt tgaaaatttt tagtcaacag attaatgcct tgattggaga
     9541 gagcggcgct gggaaaagtt tgattgctaa agccttactt gaatatttac catttgattt
     9601 aagctgcacg tatgattcgt accaatttga tggagaaaat attagtagat tgagtcaata
     9661 ttatggtcat acaattggtt atatttctca aaattatgca gaaagtttta acgaccatac
     9721 taaattaggt aaacagttaa ctgcgattta tcgtaagcat tataaaagta gtaaagaaga
     9781 ggctttgtca aaaattgaca aggctttgtc gtgggttaat ttacaaagca aagatatatt
     9841 aaataaatat agtttccaac tttctggggg ccaacttgaa cgcgtttaca tagcaagcgt
     9901 tctcatgttg gagcctaaat taatcattgc agacgaacca gttgcatcat tggatgcttt
     9961 gaacggtaat caagtgatgg atttattaca gcatattgta ttagaacatg gtcaaacatt
    10021 atttattatc acacataact taagtcatgt attgaaatat tgtcagtaca tttatgtttt
    10081 aaaagaaggt caaatcattg aacgaggtaa tattaatcat ttcaagtatg agcatttgca
    10141 tccgtatact gaacgtctaa ttaaatatag aacacaatta aagagggatt actatgattg
    10201 agttaaaaca tgtgactttt ggttataata aaaagcagat ggtgctacaa gatatcaata
    10261 ttactatacc tgatggagaa aatgttggta ttttaggcga aagtggctgt ggtaaaagta
    10321 cgctcgcttc attggttctt ggcttgttta aacctgttaa aggagaaatt tacttaagtg
    10381 ataatgctgt gttaacgatt ttccaacacc ctttaactag ctttaaccct gattggacga
    10441 ttgagacctc attaaaagaa gcgttatatt attacagagg cctaactgat aatactgctc
    10501 aggatcaatt attattacaa catttatcta cttttgagtt aaacgcgcaa ttattgacta
    10561 aattaccaag cgaagtgagt ggcggacaat tacaaagatt taatgtcatg cgttcgttat
    10621 tagcacagcc tcgcgtttta atatgtgatg agataacttc aaatttagat gttatagctg
    10681 aacaaaatgt aatcaatata ttaaaagcgc aaacgattac gaacttaaat cattttatcg
    10741 ttatttctca tgatttatcc gtgttacaac gcttagttaa tagaattatc gttcttaagg
    10801 atggcatgat agtcgatgat tttgcaatag aggaattatt taatgttgat agacaccctt
    10861 atacaaaaga attagtgcaa acattttcat attagctatt taagaatgcg ataattctag
    10921 acttgttata aaatatagat gaatcaagta tattaatcta gacacttatc gattttattt
    10981 tctttattta aaaataataa taaaaaggag tatcattaat gggattactt gatattgcaa
    11041 gtattcgttc tatagaaaga ggctttaatt attatcaaag tgaatgcgtc attaacttaa
    11101 aatcattttc agaaacgcag catgaggctg aagtaaaggg cagtggcaac aaagtatatc
    11161 gttgttatat tgatatggaa catcctagaa aatccaaatg taattgtcct catgctgatg
    11221 gaagacgagt gatatgtaaa catatgattg cattactctt tacagctagt ccagaagcag
    11281 caaataaaca tataatgatg ttaaacgaag ttgaagaaga ctatcaatta cgcagaaata
    11341 tgtggattga tagtcttaaa gaaatgatta atgatatgag tgaagaagaa ctccgcgatg
    11401 catatttaaa catgttaatt gaacatggag aaatggcaga attatttgga ttagatgaag
    11461 aggaagaaat gttcgaggac gaattttatt aaaatagccc ctatcgattg ataatgatta
    11521 tcatttgata ggggtgcttt tatttatatg attttaagac tttgcaaata gcttgtgtat
    11581 tattattgat gtgtttgatt ttatcaagtt tcaatattgc gtgtgtgtat gcttctgatg
    11641 gtcctataat atagccacta ctagcatgtt gtaacatgaa aatatcattg tggtcattac
    11701 caaatgctat atatttaaca tctgcatcaa atatatattg taatgcagta tatttattaa
    11761 tattttgcgc tgttatatca atgttatact catttgaatg gtgaatcatt tccaattctt
    11821 gatggtattt atttagctcg tctaatatag ttgtaatttg tgccgggtct atatttaata
    11881 aaatgatctt gattggtgtg tcgatatttg caacatcaat acaactggcc agcttatgtg
    11941 gatctaaacg ctcaaaaatc gcgttctcag cgtcaagttg tgcagcataa ttccaatcat
    12001 catcaataat ataatctaac tcatactttt gaattatttt taagatatgg tgatatgtat
    12061 ctgtatgaat tggtttgata acagaaatct ttgattgctg tgaaatcata gcaccatttg
    12121 cgccaattaa tgtgtgctga tgaaatactg atggtaaaac tggcaacaaa tcacgaatcg
    12181 gacgtgctga tgcaaatata agttcatgac catcatgttg taattgtaac aatgtatcaa
    12241 taatagtctg gtcaattaat cggccgtcaa aacaaagcgt accatcaata tcaaagacaa
    12301 atctcatcaa atcactccaa acaatataat accatgatta tagcataagt aagttatgtg
    12361 acgatattag ataatgatta tgatgtaggg taccttttgc gtcacacaca ttacttccta
    12421 taatatatat tatgtaaact agaatgtgaa attccataag gggacttata taacttcgat
    12481 tttgtataag tcgttttgat tattagtaaa gtatgtttgt agttactatt aactttttat
    12541 ttaacacatg ctattttatc aatacctcta ttattaggat tagtacataa ataaactaaa
    12601 attaacgcga caaaatttag aaaatctata aaaataaata agatttgtgc agattgagtt
    12661 tgatatatga ccaaaagtat tgaaagtaaa aatagtagga ttaatattaa ttttaaacaa
    12721 gatataatta atggtaaaca tctgacaact ggttttcgtt cttttaataa agaacacgaa
    12781 aagaataacc acattattat agaaaagtta cacactagat atgtactaaa agaaatacca
    12841 ccttcttgta tgacatatct aaataagttc acagcaaatt catgattatt atgaatattt
    12901 gactcactaa ttaaactaat tgtaaattct gcagtgaatc cttgaataat caacgaaatt
    12961 ccatta
//
LOCUS       DAPDIM010000072        12674 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000072 DAPDIM010000000
VERSION     DAPDIM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 12674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12674
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.072"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..598)
                     /gene="sdpA"
                     /locus_tag="RFE25_002319"
     CDS             complement(<1..598)
                     /gene="sdpA"
                     /locus_tag="RFE25_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease SdpA"
                     /protein_id="HDU2817355.1"
                     /translation="MQKFKDFFYDDLSVTRGNYFLTLMAAFFITIILFIGIVVSEVHL
                     LYSMLIVLVGLILLRLFKINLFSFKKLTLSQVIYIIGGALLIYGLDNLYLYFHDVPAN
                     ELQLEQEIRNTPFYISIFTVTIIPAIVEEIVFRGMIIRVIFRKHLFLGLLVSSLVFAS
                     LHESDTWIGYLPYLYSGLIFGLIYIKTKRLEVVIFMHFL"
     gene            894..1337
                     /locus_tag="RFE25_002320"
     CDS             894..1337
                     /locus_tag="RFE25_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817356.1"
                     /translation="MNKASFDKKVKKQLWFLNKKEKQALDQRLSSISDDDSVNLNKPV
                     TFANAYLRQNVFRNKETKSYSMFVTLVVMMFAYVALLGLFLFGLITSLSGVQFFVSPK
                     VDLSTTVVILTIIGAILLMIVSIYFIKIVTSYFTKKLLEIKFNSK"
     gene            complement(1324..1767)
                     /locus_tag="RFE25_002321"
     CDS             complement(1324..1767)
                     /locus_tag="RFE25_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComK"
                     /protein_id="HDU2817357.1"
                     /translation="MQDNSTKYLLYIQTATSNHLETNCVFLHCDYILKVPINKLVSYY
                     AKLHLSSQSVLIETAKNILNINKLVPIYINPKTILFPLKHKRAPIQIYINAHYIVGMT
                     AIENSTLIHFQEGIQLEVDEPFSLVSKKCHESLALKHFIENTISN"
     gene            complement(1880..2350)
                     /gene="sigS"
                     /locus_tag="RFE25_002322"
     CDS             complement(1880..2350)
                     /gene="sigS"
                     /locus_tag="RFE25_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor SigS"
                     /protein_id="HDU2817358.1"
                     /translation="MKFNDVYNKHHKIIHHLLKKYNISYNYDEYYQLLLIKMWQLSQI
                     YKPSSKQSLSSFLFTRLNYYLIDLFRQQNQLKDVILCENNSPTLTEQPTYFNEHDLRL
                     QDIFKLLNHRERLWLKLYLEGYKQFEIAEIMSLSLSTIKLIKMSVKRKCQHNFN"
     gene            2549..2773
                     /locus_tag="RFE25_002323"
     CDS             2549..2773
                     /locus_tag="RFE25_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817359.1"
                     /translation="MDYAHLNLEHFFARNDDLDVIRDRADFVMINNFTNEMMYRDGQI
                     EGTIDLNQYYYKNRSNAASFIMMDYKKETK"
     gene            3049..3903
                     /locus_tag="RFE25_002324"
     CDS             3049..3903
                     /locus_tag="RFE25_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDU2817360.1"
                     /translation="MNKHKKGSIFGIIGLVVIFAVVSFLFFSMISDQIFFKHVKSDIK
                     IEKLNVTLNDAAKKQINNYTSQQVSNKKNDAWRDASATEIKSAMDSGTFIDNEKQKYQ
                     FLDLSKYQGIDKNRIKRMLVDRPTLLKHTDDFLKAAKDKHVNEVYLISHALLETGAVK
                     SELANGVEIDGKKYYNFYGVGALDKDPIKTGAEYAKKHGWDTPEKAISGGADFIHKHF
                     LSSTDQNTLYSMRWNPKNPGEHQYATDIKWAESNATIIADFYKNMKTEGKYFKYFVYK
                     DDSKHLNK"
     gene            complement(3990..5282)
                     /gene="arsB"
                     /locus_tag="RFE25_002325"
     CDS             complement(3990..5282)
                     /gene="arsB"
                     /locus_tag="RFE25_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite efflux transporter membrane subunit
                     ArsB"
                     /protein_id="HDU2817361.1"
                     /translation="MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAVITGVVS
                     FSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEWSAIHMLHASKGNGLKMFVYIIL
                     LGAIVAAFFANDGAALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSN
                     LVNIISADYFHVGFVRYFSRMIIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKHPKD
                     AINDLKLFKISWIVLVILLFGYLISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKQV
                     IKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLFSTILGMGFISAFLS
                     SIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVL
                     TQKDVKISWGTYFKTGIIITIPVLFITLIGLYLTLIIF"
     gene            complement(5282..5596)
                     /locus_tag="RFE25_002326"
     CDS             complement(5282..5596)
                     /locus_tag="RFE25_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDU2817362.1"
                     /translation="MTYKELATFLKVLSDSSRLEILDLLSCGELCACDLLAHFQFSQP
                     TLSYHLKALVKTNLVTTRKIGNKHLYQLNHNIFESVINNLSKVHTSNQRCFCHNLKTG
                     EC"
     gene            6119..7621
                     /locus_tag="RFE25_002327"
     CDS             6119..7621
                     /locus_tag="RFE25_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDU2817363.1"
                     /translation="MRVAIIGMGTAGVSVLRELVKHPKFNQLDIDLYDDKVNMGQGVP
                     FQNDSSELLINMPSKKMSLNLDDETEFWKWYKQQTDFNFDEPAYLPRFVFGHYMKSYL
                     SMFTKKYPNISTNYNKVQEIYTNSNIDETNLTYYICTTNSEQSWQAYDYVFLTCGTFA
                     YHDPYNLKGKKGYIATPYPTYNTLDEVNELDDIAIIGTGLASLDVVRYVAAHHPKLPI
                     TMTSRSAHLPSVRGTMIDVTFKYLTKDKLNDIKKHHFGNAPLDTIVSLFLKECAEYDI
                     DFKKLVHRRTGNHIADLKYDLARPTEMGIFQSMIEHLKENLNWIWNSLSIEDQHQFNQ
                     KYSKMIQLNSNPMPPRTAELIIELIENKSLILKKDLEDVKHDGKLYYFSYKNQESVDM
                     YNVVINATGAKSHLNELDQDDQLIKNLENRQIVQAHPMGGIQIIPETNQVISPRFGTL
                     TNMIAIGQMTNGVNKLRNGVKMIVEQVAHTVSQLYDALESNEQQQRSYNQ"
     regulatory      7840..7975
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            8102..9145
                     /gene="ribD"
                     /locus_tag="RFE25_002328"
     CDS             8102..9145
                     /gene="ribD"
                     /locus_tag="RFE25_002328"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDU2817364.1"
                     /translation="MSQFMDYAIQLANMVQGQTGVNPPVGAVVVNEGRIVGIGAHLRK
                     GDKHAEVQALDMAQQNAEGATIYITLEPCSHFGSTPPCVNKIIDCKIAKVVYATKDNS
                     LDTHGDETLRAHGIEVECVDDERASQLYQDFFKAKAKQLPQITVKVSASLDGKQANDN
                     GQSQWITNKEVKQDVYKLRHRHDAVLTGRRTVELDDPQYTTRIQDGKNPIKVILSKSG
                     NIHFNQQIYQDESTPIWIYTENPNLTSNQTHIEIIYLKSCDLTTILHNLYKRGVGTLL
                     VEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQFYQTNDVIEIPDANQFEIVHSE
                     LLNQNVKLTLRKK"
     gene            9152..9784
                     /locus_tag="RFE25_002329"
     CDS             9152..9784
                     /locus_tag="RFE25_002329"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDU2817365.1"
                     /translation="MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVN
                     GACLTVIDFDQTSFTVQVIKSTENKTYLADVKRQSEVNLERAMSGNGRFGGHFVLGHV
                     DELGTVSKINETANAKIITIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLI
                     PETRRSTILSSKKLGDKVHLETDVLFKYVENILNKDKDQLSVDKLRAFGF"
     gene            9795..10976
                     /locus_tag="RFE25_002330"
     CDS             9795..10976
                     /locus_tag="RFE25_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDU2817366.1"
                     /translation="MQFDNIDSALMALKNGETIIVVDDENRENEGDLVAVTEWMNDNT
                     INFMAKEARGLICAPVSKDIAQRLDLVQMVDDNSDIFGTQFTVSIDHVDTTTGISAYE
                     RTLTAKKLIDPSSEAKDFNRPGHLFPLVAQDKGVLARNGHTEAAVDLAKLTGAKPAGV
                     ICEIMNDDGTMAKGQDLQNFKEKHQLKMITIDDLIEYRKKLEPEIEFKAKVKMPTDFG
                     TFDMYGFKARYTDEEIVVLTKGAIRQHENVRLHSACLTGDIFHSQRCDCGAQLESSMK
                     YINEHGGMIIYLPQEGRGIGLLNKLRAYELIEQGYDTVTANLALGFDEDLRDYHIAAQ
                     ILKYFNIEHINLLSNNPSKFEGLKQYGIDIAERIEVIVPETVHNHDYMVTKKIKMGHL
                     I"
     gene            10989..11453
                     /locus_tag="RFE25_002331"
     CDS             10989..11453
                     /locus_tag="RFE25_002331"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDU2817367.1"
                     /translation="MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNE
                     DNIDVAFVPGAFEIPLVAKKLASSGNYDAIITLGCVIRGATSHYDYVCNEVAKGVSKV
                     NDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA"
     gene            complement(11575..12576)
                     /locus_tag="RFE25_002332"
     CDS             complement(11575..12576)
                     /locus_tag="RFE25_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline dehydrogenase"
                     /protein_id="HDU2817368.1"
                     /translation="MALLKNFFIGLSNNSFLNNAAKKVGPRLGANKVVAGNTIPELIN
                     TIEYLNDKNIAVTVDNLGEFVGTVEESNHAKEQILTIMDALHQHGVKAHMSVKLSQLG
                     AEFDLELAYQNLREILLKANTYNNMHINIDTEKYASLQQIVQVLDRLKGEFRNVGTVI
                     QAYLYDSHKLVDKYQDLRLRLVKGAYKENESIAFQSKEDVDANYIKIIEQRLLNARNF
                     TSIATHDHRIINHVKQFMKENHIEKDRMEFQMLYGFRSELAEEIANEGYNFTIYVPYG
                     DDWFAYFMRRLAERPQNLSLAVKEFVKPAGLKRVGIIAALGATVMLGLSTIKKLCRK"
BASE COUNT         4635 a         1741 c         2175 g         4123 t
ORIGIN      
        1 ttaagaagtg catgaatatt accacttcta atcgttttgt ttttatataa attagaccaa
       61 aaatcaaacc agaatataag taaggtaaat aaccaatcca agtgtcagat tcgtgtaatg
      121 atgcaaaaac taaactagac acaagtaacc ctaaaaataa gtgttttctg aatataaccc
      181 ttattatcat accgcgaaaa acaatttctt ccacaatagc ggggatgatg gtaacagtga
      241 aaatagaaat atagaatggt gtatttcgta tttcttgctc taattgtagt tcatttgccg
      301 gtacgtcatg aaaatataaa taaagattat ctaacccata aattaatagt gcaccgccta
      361 taatataaat aacttgagac aatgttaatt ttttaaaaga gaataaattg attttgaata
      421 gcctcaatag aattaaacct actaatacaa ttagcatgct ataaagtaaa tgtacttcac
      481 tgacaactat gccgataaat aaaatgatag taataaaaaa tgctgccatt aaagttaaaa
      541 aataatttcc tcgtgtaacc gataaatcat cgtaaaaaaa gtctttgaat ttttgcatgc
      601 taaatccttt cttttcattt tttaaaatta ttttgaatgc aatatggtta aggctagatt
      661 cattatatat gaaacatata tacgattaaa atttatcatt gtacctacct aaaaagcatt
      721 agtttgaaaa attagcagac tgtattttag cgtcaaatca ccataaatga aattgtaata
      781 tggatttttg tagatttgat acatatattt ctgtaaaata tataaaatac actttcaatt
      841 gacgctaatg tttaaaatta cgtcaatatt ataaaggaga gaaatcctta attatgaata
      901 aagcatcatt tgataaaaaa gttaaaaagc aattatggtt tttgaacaag aaggagaaac
      961 aagcattaga tcaacgatta tcttctatat ctgatgatga cagcgttaac ttaaataagc
     1021 ctgttacctt tgctaatgct tacttaagac aaaatgtatt tcgaaataaa gaaacaaaaa
     1081 gttatagtat gtttgttaca ttagtagtga tgatgtttgc ttatgttgct ttattaggct
     1141 tgtttttatt tgggctaatt acaagtctat ctggcgtaca atttttcgtt agtcctaagg
     1201 tagatttatc aacaactgtt gttattttaa caattattgg agcgatttta ttaatgattg
     1261 ttagcatata ttttataaaa attgtgacat catactttac taagaaactt ttagaaatta
     1321 aatttaattc gaaatagtat tttcaatgaa gtgcttcaaa gctaaacttt catgacattt
     1381 ttttgaaact agagaaaatg gctcatcaac ttctagctga atgccttctt gaaaatgtat
     1441 taatgttgaa ttctctatgg cagtcatacc aacaatataa tgtgcattga tataaatttg
     1501 tatcggtgca cgtttatgtt ttaacggaaa aagtatagtt tttgggttga tgtaaatagg
     1561 aaccagttta ttaatattta gtatgttttt tgcagtctca attagcacac tttgtgatga
     1621 taaatgcaat ttcgcataat atgaaacgag tttgttaatt ggaactttaa gaatgtaatc
     1681 gcaatgtaaa aagacacaat ttgtttcgag atggtttgaa gtagcagttt ggatataaag
     1741 tagatattta gtagaattgt cttgcaaata tagtactcct cgtataataa gttgttaatt
     1801 taatggttaa aataaattta tatgaagatg ttagggtgtt tcaacatcac taacacatcg
     1861 accgaaattt cacaataaac taattaaaat tatgttggca tttacgctta acggacatct
     1921 taattaattt aatcgttgaa agcgataatg acatgatttc agcaatttca aattgcttgt
     1981 atccttcaag gtatagtttg agccatagtc tttctctatg atttaaaagc ttgaagatat
     2041 cttgtaaacg aaggtcatgt tcattaaagt atgttggttg ttcagttaat gttggtgaat
     2101 tattctcaca taaaatgaca tcttttaatt gattttgttg tctgaataaa tcgataaggt
     2161 aataatttaa tcgagtgaat aaaaaagagg ataaagattg cttgcttgag ggtttatata
     2221 tctgactcaa ttgccacatt tttatcaaga gtagttgata atactcatca taattatagc
     2281 taatattata tttttttaaa agatggtgta tgattttgtg gtgtttgttg tatacgtcat
     2341 taaatttcaa gtagtcattc tccaagttat acgtataaca aatatttccg gataaagtta
     2401 gaataaaata tttagaaaaa tcattcattt gcgtaatcgc taaattaagt gttaaatata
     2461 agacataagt aattaattta atgtgatatg atgtattatt actttgctaa atagtagata
     2521 gaacaaaatt tgtaatcggg aggtaacaat ggattacgca catttaaatt tagaacattt
     2581 ttttgcacga aacgacgatt tagatgttat aagagatcgc gctgatttcg tgatgataaa
     2641 taacttcact aatgaaatga tgtatcgtga tggtcaaatt gaaggcacga ttgatttaaa
     2701 tcagtactat tataaaaata gatcaaatgc agcaagtttt attatgatgg attataaaaa
     2761 agaaactaag taaacgaaca aaagaatttt ttgtttttta atacgtgaat aataagatta
     2821 ttgatataaa ggttttcaaa ggttatacaa aaagataaaa catttatgat tcgtagatca
     2881 acgtaaagta atgttgataa atggtttaaa acgtttcatt tacattactg tttatttatg
     2941 aatatgtaac aatgcataga taaaattgtt aaacggtttt aataatgtta aactttatta
     3001 tcgtagtcaa actgaatgta taacaacaat gacctaagag gtgtggatat gaataaacac
     3061 aagaaaggtt ctatttttgg aataatagga cttgttgtca tatttgctgt tgtctcattt
     3121 ttatttttct caatgatatc cgatcagata tttttcaaac atgttaaatc cgacattaag
     3181 attgaaaagt taaatgttac attaaacgat gcagcaaaga aacaaataaa taattatacg
     3241 agtcaacagg tatcaaataa aaagaatgat gcatggagag atgcatctgc aactgaaatt
     3301 aaaagtgcaa tggatagcgg tacttttatc gataatgaaa agcaaaaata tcaattttta
     3361 gatttatcaa agtatcaagg gattgataaa aatagaatta aacgtatgtt agtagataga
     3421 ccaacgttat tgaaacatac ggatgatttc ttaaaagctg ctaaagataa gcacgttaac
     3481 gaagtttatt taatttcaca tgcattatta gaaactggcg cagttaaaag tgaattagct
     3541 aatggagtcg aaattgatgg caaaaaatac tacaatttct atggagtagg agcccttgat
     3601 aaagacccaa ttaaaacagg tgcagaatat gctaaaaagc atggttggga tacacctgaa
     3661 aaagctattt caggcggtgc tgatttcatt cataagcact tcttatcaag cacagatcaa
     3721 aatacattgt atagtatgag atggaatcca aaaaatccag gagaacatca atatgctact
     3781 gatattaagt gggcagaaag taatgcaaca attatcgctg acttttataa gaatatgaag
     3841 actgaaggaa aatacttcaa atactttgtg tataaagatg acagtaaaca tttgaataag
     3901 taatttgata gagttaagtt atgatataac ttgctcaagt ataaaaagac gctttctatc
     3961 gcaataaata gaaagcgtct ttttatttct taaaatatga taagtgttag atacaaccct
     4021 atgagggtta taaatagtac tggaattgta atgatgatac cagttttaaa gtatgtgccc
     4081 caagaaatct taacatcttt ttgtgttaag acgtgtaacc acagtaatgt agctaaagag
     4141 cctatcggtg taatttttgg acctaaatca gaaccgataa cattcgcata aattaggcct
     4201 tcttttaaca tgccatggac atttgattga ccaatagcaa tcgcatctat taaaactgta
     4261 ggcatattat tcattattga tgataaaaac gctgaaatga agcccattcc caaaatggtg
     4321 ctaaatagac cgtaattgga aatatattct aatattttag ccaatattaa agtaatgcca
     4381 gcatttctta agccgaatac gacgatatac ataccaattg aaaataatac tatattccaa
     4441 ggtgcgccct taatgacttg cttaatattt acagcatttg atttacgagc caacattaga
     4501 aaaataaaag caatgattcc agtgaaaatt gataccggaa ttttagtaaa ttcactgatt
     4561 agatagccga aaagtaatat aactagaaca atccatgaaa ttttaaatag ctttaaatca
     4621 ttaatggcat ctttaggatg ctttatatta ttatcatcaa acgttttagg tatcgccttt
     4681 ctaaaatata accacaatac tataatactt gctaaaagcg agaataaatt aggtataatc
     4741 attctactaa aatatcgaac gaatcctaca tgaaaataat cagcagatat aatattcact
     4801 agattgctca cgatcaaagg taaagaagtt gtgtcagcta taaaaccact cgcaataata
     4861 aaagggaata tggcccgctt actaaaacct atatttttaa ccatcgctaa tacaataggc
     4921 gttaagatta acgctgcgcc atcatttgcg aaaaatgcag caacaatggc acccaataat
     4981 atgatataaa cgaacatttt taaaccattt ccttttgaag catgaagcat gtgaatagct
     5041 gaccattcga ataatccaac tttatctaat attaatgaaa taagaatgac tgagacaaaa
     5101 gtcaaagtag cattccaaac aatacctgtt acttcgaaaa catcggaaaa acttacaaca
     5161 ccagtaataa cagcaataaa ggcaccagtt aatgcggtaa tgccaatatc taggccttta
     5221 ggttgccata atacaaataa taaagttact agaaaaatga gtgtcgctaa agttgtcatc
     5281 attagcattc accagtctta aggttatgac aaaaacatcg ttggttagag gtatgaacct
     5341 tagacaagtt attaattacg gactcaaaaa tattatgatt aagctggtat aaatgtttat
     5401 ttccgatttt tcgtgtcgta actaagttgg tttttactaa tgctttcaaa tgatagctaa
     5461 gtgtgggttg agagaattga aaatgtgcta acaaatcaca agcgcataac tctccacaag
     5521 aaagtaaatc tagtatttct aatctgcttg aatctgataa aacttttaaa aatgttgcta
     5581 gttctttata cgtcataaca tacctcctag acgttaaata gattatcatc tatatagatg
     5641 aatgtctatg ttcctttggt atattacacg atatgactat gtaatttgaa tttggtttta
     5701 gtattaaaag ggtattaaag ataaattata gatattgatt ttgcaaaata tactctttgt
     5761 tttgcattga aaaaggtgat tagccatatc ttgagtgtat ggccaatcac cttagttgaa
     5821 tttattttgt aatcaagggt attgattaag aagctttgtt tttacgacta aaaatcataa
     5881 atagaattac taatgagatt aatatctttg ctataaattt caatttaatt cacctcgtta
     5941 aaaatatttt aacacaaaca ctaaggttga tattaaatga aaagttttaa atggtttaat
     6001 ggttgtgaaa gtgaaataat agcttacctt aataaatttt attggaaata ccaaattgct
     6061 ataattatag gtaatagttt aaatataata ttttgaatta caaaaggatg gatgatatat
     6121 gcgtgtagca ataataggca tgggaactgc tggtgtaagt gtattgagag agttagttaa
     6181 gcacccgaag tttaatcaat tagatataga tttatacgat gataaagtaa atatgggaca
     6241 gggcgtacca tttcaaaatg atagttctga gctgctaatt aatatgcctt cgaaaaagat
     6301 gagtttaaat ttagatgatg agactgaatt ttggaagtgg tataaacaac aaactgattt
     6361 taattttgat gaacctgcat atttaccgag atttgtattc ggacattata tgaaatctta
     6421 tttatctatg ttcacgaaaa aatatccaaa tatatcaact aattataata aagttcaaga
     6481 gatttataca aattctaata tcgatgaaac gaatttaact tattacatat gtactacaaa
     6541 ttcagaacaa tcatggcaag cgtacgatta tgtattttta acatgtggta catttgccta
     6601 ccatgatcca tataacttaa agggtaaaaa aggatatatc gctacgcctt atccaacata
     6661 taatacgtta gacgaagtaa atgaactgga cgatattgcg attattggta caggccttgc
     6721 cagtttagat gttgtccgtt atgttgctgc tcatcatccg aaattaccaa ttactatgac
     6781 gagtcgttct gctcatttac caagtgtaag agggacaatg atagacgtga cattcaagta
     6841 cttaactaaa gacaaattaa atgacattaa aaaacatcat ttcggcaatg caccgcttga
     6901 tactatagtt tctttatttt taaaagaatg tgctgaatat gacattgatt ttaaaaaatt
     6961 agtacataga cgtacaggaa atcatattgc agatttgaag tatgatttag cgcgtccaac
     7021 agaaatgggc attttccaaa gtatgattga acatttgaaa gagaatttaa attggatatg
     7081 gaatagctta agtattgaag atcaacatca atttaatcaa aaatactcaa agatgattca
     7141 attaaattca aatccaatgc ctccaagaac tgctgaacta attattgaat taatagaaaa
     7201 taagtcttta attttgaaaa aagatttaga agatgtgaaa catgatggca agttgtatta
     7261 tttttcatac aaaaaccaag aatcagtaga catgtataat gttgtcatta acgcgacagg
     7321 tgcaaaaagt catttaaatg aattggatca agatgatcaa ttaattaaaa atcttgaaaa
     7381 tagacaaatt gtacaagcac atccaatggg aggcatacaa atcataccgg aaaccaatca
     7441 agttattagt ccaaggtttg gaacattaac aaatatgatt gcgataggtc aaatgacaaa
     7501 cggtgttaat aaactacgaa atggtgtgaa aatgatagta gaacaagttg cgcatacagt
     7561 atctcaatta tatgatgctt tagaatcgaa tgagcaacaa cagcgcagtt acaatcaata
     7621 atttgtaact agaagataat aaagagaacg ctctatagag acgaattgaa ggtttgattt
     7681 taatgtctgt tagtaagaat catatcaatg agatgcctat agtactcaga ttatattaaa
     7741 ttaaaaccgt cattaattgt tttttcagaa aacatatagt atcattttaa atgtagttga
     7801 catactacgt actcaaataa tctataacaa tttcatatat aattctttcg gggcagggtg
     7861 aaattcccaa ccggcagtaa ataaagcctg cgacctgcta atatgtttca tattagtggc
     7921 tgatctagtg agattctaga gccgacagtt aaagtctgga tgggagaaag aatgttaatt
     7981 atcgacaaag ataatgtagc gtatttgtaa aaatgtgtac aaataggctt atttaacgat
     8041 aaatttttct ccttgcatct taattcatga tgtgaggatt tttgtttata gaggtgatca
     8101 tttgagtcaa tttatggatt atgcgattca acttgcaaat atggtacaag gtcaaacagg
     8161 tgttaatcca cccgttggcg ctgttgtagt taatgaaggt aggattgttg gtattggtgc
     8221 acacttgaga aaaggtgaca agcatgcgga ggttcaagca cttgatatgg cacaacaaaa
     8281 tgctgaaggt gcgacgattt atattacgtt agagccatgt agtcattttg gttcaacacc
     8341 accctgtgtt aacaaaatta ttgattgtaa gatagcaaaa gtagtatacg caacaaaaga
     8401 caattcgtta gacacacatg gtgatgagac gttacgggct cacggtattg aggttgaatg
     8461 cgttgatgat gaacgggcat cacaattata ccaagacttt tttaaagcaa aagcaaagca
     8521 actgccacaa attacagtga aagtatctgc aagtttagat ggtaaacaag cgaatgataa
     8581 tggacaaagt caatggatta ctaacaaaga ggttaaacaa gatgtctata agttaagaca
     8641 tcgacacgac gcagtgttaa ctggaagacg tacagttgaa ttagatgatc cacaatatac
     8701 tacacgtatt caagatggaa aaaaccctat aaaagtaata ttgtctaagt ctgggaatat
     8761 tcattttaat cagcaaattt atcaagatga atcaacacca atttggatat atactgaaaa
     8821 tccaaattta acaagcaatc aaacacatat tgaaattatt tacttgaagt cttgtgattt
     8881 aacaacaatt cttcacaatt tatataaaag aggagttgga actttgctag tcgaggcagg
     8941 tccaaccact acttcagaat ttctccaatc taattatata gatgaattta ttctctatta
     9001 tgccccgaaa ttaattggcg gatctggaaa ttatcaattt tatcaaacaa atgatgtgat
     9061 tgagatacca gatgcgaacc aatttgaaat tgttcattcc gagttattaa atcaaaatgt
     9121 taaattaact ttacgaaaga agtgatgatg catgtttact ggcatcgttg aagaaatagg
     9181 tgtcgttaaa agtgttcaaa ttcgtcaatc agtcaggacg attgaaatcg aagcacataa
     9241 gattacggca gatatgcata ttggtgattc catcagtgtt aatggtgcat gtttaacagt
     9301 gattgatttt gatcagacat cttttactgt tcaagtaatt aaaagcactg aaaataaaac
     9361 ctatttagca gatgttaagc gacaatcaga agtaaattta gagcgtgcca tgagtggtaa
     9421 cggtaggttt ggtggacatt ttgtcctcgg tcatgtagat gaactaggaa cagtttcaaa
     9481 aataaatgaa acagccaatg ccaaaattat tacgattcaa tgtagccaac atattaataa
     9541 tcagttagtt aagcaagggt ctattactgt ggatggtgta agtctaacgg tatttgataa
     9601 gcatgataac agttttgaca ttcatcttat tccagaaacg aggcgttcaa cgattttatc
     9661 atccaaaaaa ttaggagata aagtacattt agaaacagac gttttgttta aatatgttga
     9721 aaatatttta aataaagata aagaccaatt atctgtagat aaattaagag catttggttt
     9781 ttaggagggg tagcatgcaa ttcgataata ttgacagtgc tttaatggct ttaaaaaatg
     9841 gagaaacaat tattgtagta gatgatgaga atcgtgaaaa tgaaggtgat ttagtagcgg
     9901 ttactgaatg gatgaacgat aataccatta attttatggc gaaagaagca aggggattaa
     9961 tatgcgcacc agtgtctaaa gatattgcac aacgtttgga tttggtacaa atggttgatg
    10021 ataactccga catctttggt acgcaattta cagtgagtat tgatcatgta gatacaacaa
    10081 caggaattag tgcttatgaa cgtacattga ctgccaaaaa gctcattgat cctagtagtg
    10141 aagctaaaga ttttaatcgt cctggtcatt tatttccatt agtagcacaa gataaaggcg
    10201 tattagctag aaatggacac acagaagcgg ctgttgattt agctaaactt actggtgcca
    10261 agcccgctgg tgtcatttgt gagattatga atgatgacgg cacgatggcg aaaggacaag
    10321 atttacaaaa ttttaaagaa aaacatcaat taaagatgat tacgattgat gatttaattg
    10381 aatatcgtaa aaaattagaa ccagaaattg aatttaaggc aaaagtgaaa atgcctacag
    10441 atttcggaac atttgatatg tatggtttta aagcgagata cacagatgaa gagatagttg
    10501 tactgacaaa aggtgcaatt cgacaacatg aaaatgtacg cttacattct gcgtgcctta
    10561 caggcgatat tttccatagt caacgttgtg attgtggtgc tcaacttgaa tcgtctatga
    10621 agtatatcaa tgaacatggt ggcatgatta tttatctacc tcaagaaggt cgtggcatag
    10681 gattgttaaa caaattacgc gcatatgaat taattgagca aggatatgat acagtaactg
    10741 caaatttagc attaggtttt gatgaagatt tacgagatta tcatattgct gcacagattt
    10801 taaaatattt taacatcgaa catatcaatt tattaagtaa taatccaagt aaatttgagg
    10861 gattaaaaca atatggcatt gatattgcag aaagaattga agttatcgta ccagaaacgg
    10921 tacataatca tgattatatg gtaacgaaaa aaataaaaat gggtcattta atataggagg
    10981 actttaacat gaattttgaa ggtaaattaa ttggaaaaga tttgaaagtt gcaatcgtag
    11041 ttagtcgatt taatgatttt atcactggaa gattacttga aggtgcaaaa gatactttga
    11101 ttcgacatga tgttaatgaa gacaatattg atgtagcatt tgttcctggt gcgtttgaaa
    11161 ttcctttagt agctaaaaaa ttagcctcat caggaaatta tgatgcaata attacattag
    11221 gatgcgtaat tcgcggtgct acgtctcatt atgattatgt ttgtaatgaa gtcgcgaaag
    11281 gtgtttctaa agtaaatgat caaactaatg taccagtcat atttggtatt ttaacgactg
    11341 aaagtattga acaagctgtg gaaagagcag gtacgaaagc tggtaataaa ggtgccgaag
    11401 cagcagtaag tgcaattgaa atggctaatt tattaaaatc tataaaagca tagagcgctg
    11461 ttgtgagttc ataatcaaag atttataaat gtttcagaac tgccaatata acatttagga
    11521 gcctagaaca ttgattattg ttccagactc ctaaattatt gtttatgcca tgctctattt
    11581 acggcataat tttttaattg tacttaaacc taacataact gtagctccta aagctgcaat
    11641 tatgccaaca cgttttaagc cagcaggttt cacaaattct tttacagcaa gagataggtt
    11701 ttgtgggcgt tctgctaatc ttctcataaa atacgcaaac caatcatcgc cataaggtac
    11761 ataaatagtg aaattatagc cttcatttgc gatttcttct gctaactctg atctaaaacc
    11821 atagagcatt tggaattcca tacgatcttt ttcaatgtga ttttctttca taaattgttt
    11881 tacatgatta atgatgcgat ggtcatgtgt tgcaattgaa gtgaaattgc gtgcgtttaa
    11941 caaacgttgt tcaattattt tgatgtaatt tgcatctacg tcttccttag attgaaatgc
    12001 aattgattcg ttttctttat atgcaccttt aaccaaacgt aatcgtaaat cttggtactt
    12061 atcaactaat ttgtggctat cgtataaata tgcttgaatt acagtaccaa catttctaaa
    12121 ttcgcctttt aagcgatcta aaacttgaac aatttgttgc aggctagcat atttttcagt
    12181 atcaatattt atatgcatat tgttgtaagt atttgcttta agtaaaattt ctcttaaatt
    12241 ttggtaagct aattctaagt cgaattctgc acctaactga ctcaatttaa cagacatatg
    12301 tgcctttacg ccatgttgat gaagcgcgtc cataattgtt aaaatttgtt ctttagcatg
    12361 attactttct tcaactgtac cgacaaattc ccctaaattg tctaccgtaa cagcgatatt
    12421 cttgtcattt aagtattcga ttgtattaat taactctgga attgtatttc cggcaacgac
    12481 tttattggcg cccaaacgtg ggcccacttt ttttgctgcg ttgtttaaaa aactattatt
    12541 agataatccg ataaaaaaat tctttaatag tgccattgct actcctccaa acccttgtgt
    12601 ttacaataag tttagcatga aaaaaatatt cgagaaagcg ttttcataaa aaacaatcaa
    12661 aaataattat gtat
//
LOCUS       DAPDIM010000073        12233 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000073 DAPDIM010000000
VERSION     DAPDIM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 12233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12233
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.073"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..283
                     /locus_tag="RFE25_002333"
     CDS             <1..283
                     /locus_tag="RFE25_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2817369.1"
                     /translation="KRRAQVGKPVSNRWGNAKNWYYNARKSKYATGRTPRKFAVMQST
                     AGYYGHVAVVEQVYKNGSIKVSEYNFYRPLKYNTRVLSKKAARNFNYIY"
     gene            complement(422..1699)
                     /locus_tag="RFE25_002334"
     CDS             complement(422..1699)
                     /locus_tag="RFE25_002334"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HDU2817370.1"
                     /translation="MQSLDKNFRHLSRQQKLQQLVDKQWLSEDQFDILLNHPLIDEEV
                     ANSLIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTGGFK
                     TVSSERIMIGQIVFDGVDDTEKLSADIKALEKQIHKIADEAYPSIKARGGGYQRIAID
                     TFPEQQLLSLKVFVDTKDAMGANMLNTILEAITAFLKNESPQSDILMSILSNHATASV
                     VKVQGEIDVKDLARGERTGEEVAKRMERASVLAQVDIHRAATHNKGVMNGIHAVVLAT
                     GNDTRGAEASAHAYASRDGQYRGIATWRYDQKRQRLIGTIEVPMTLAIVGGGTKVLPI
                     AKASLELLNVDSAQELGHVVAAVGLAQNFAACRALVSEGIQQGHMSLQYKSLAIVVGA
                     KGDEIAQVAEALKQEPRANTQVAERILQEIRQQ"
     gene            1954..3120
                     /locus_tag="RFE25_002335"
     CDS             1954..3120
                     /locus_tag="RFE25_002335"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HDU2817371.1"
                     /translation="MTIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAV
                     SPVNQDIVSMGANAAKDIITDEDKKKIGMVIVATESAVDAAKAAAVQIHNLLGIQPFA
                     RCFEMKEACYAATPAIQLAKDYLATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAM
                     VIAHNPSILALNEDAVAYTEDVYDFWRPTGHKYPLVDGALSKDAYIRSFQQSWNEYAK
                     RQGKSLADFASLCFHVPFTKMGKKALESIIDNADETTQERLRSGYEDAVDYNRYVGNI
                     YTGSLYLSLISLLENRDLQAGETIGLFSYGSGSVGEFYSATLVEGYKDHLDQAAHKAL
                     LNNRTEVSVDAYETFFKRFDDVEFDEEQDAVHEDRHIFYLSNIENNVREYHRPE"
     gene            complement(3285..3806)
                     /locus_tag="RFE25_002336"
     CDS             complement(3285..3806)
                     /locus_tag="RFE25_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDU2817372.1"
                     /translation="MEYKSYYDSPVRRLELLSDGVSLTAVLFENQQGDGTREENTSLA
                     IFREATQWLDAYFKGDNPEITIPLKPTGSHFQQCVWNELRQVPYGTLTTYGAIAKKVG
                     KVLDKPKMSAQAVGGAVGSNPLSIIVPCHRVVGKTGSLTGFGGTINNKIKLLELENID
                     MSKLYIPKHSTKP"
     gene            4215..6320
                     /gene="clpL"
                     /locus_tag="RFE25_002337"
     CDS             4215..6320
                     /gene="clpL"
                     /locus_tag="RFE25_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpL"
                     /protein_id="HDU2817373.1"
                     /translation="MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEEL
                     AQLTQQGSNQSAEQSAQAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIG
                     RDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
                     DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLS
                     DILKPALSRGEISIIGATTQDEYRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIR
                     EKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVE
                     TEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTI
                     QRLTGIPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPI
                     GSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEYSDTTAVSKMIGTTAGYVGY
                     DDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTI
                     IICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLL
                     DDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHT
                     DVKHVDIDVEDNELVVKGK"
     gene            complement(6389..6559)
                     /locus_tag="RFE25_002338"
     CDS             complement(6389..6559)
                     /locus_tag="RFE25_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDU2817374.1"
                     /translation="MSVIINILIFLAIFGYALYTLVKFFKRSKQGKCGTCDINRDCCG
                     IEQHTANHFPGK"
     gene            complement(6572..8566)
                     /gene="feoB"
                     /locus_tag="RFE25_002339"
     CDS             complement(6572..8566)
                     /gene="feoB"
                     /locus_tag="RFE25_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDU2817375.1"
                     /translation="MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLK
                     ENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNVQLTVQLLE
                     LNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKYLLGEIKHLGE
                     GYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEV
                     VNKLSSLRDQVAEQVGAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKIL
                     THKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFL
                     QDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKS
                     FIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQ
                     SLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAK
                     GFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQA
                     GATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVST
                     VAAIRKETYSWKWTALAVAYPLVTAYVLTFIFYQVGHLFV"
     gene            complement(8578..8805)
                     /locus_tag="RFE25_002340"
     CDS             complement(8578..8805)
                     /locus_tag="RFE25_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDU2817376.1"
                     /translation="MLNIKNGEMNKAYKIKRMDIANENMLYRLSAFGLTDDAIITIKQ
                     KCLFKGPCIIEVNGQQLSIRHCDACSIALEE"
     gene            complement(9021..11510)
                     /gene="farE"
                     /locus_tag="RFE25_002341"
     CDS             complement(9021..11510)
                     /gene="farE"
                     /locus_tag="RFE25_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid efflux MMPL transporter FarE"
                     /protein_id="HDU2817377.1"
                     /translation="MAKFLYKMGTFIAKHKWSAVIAWIVIVAAILIPLATNAPKFDND
                     IKMTGLESLDTNKKIEKHFNQDSEKAQIRVVFKTTKDDGIVQPNITEDIKKTLEDIKK
                     DDKHIDKISDPYENKQISKDKTTAFADITYDVSQTSLKDGSRDNVKSHLKDLRDNHNV
                     QTELTGTGMTSTEVGGNSELVGIIVAFVVLLITFGSVIAAGLPIISALIGLASGVGII
                     SLLTYAFDIPNVTLTLAVMIGLAVGIDYALFILFRYRQVMKTETDYIKGIGLAIGTAG
                     SAVVFAGVTVVIAVCGLSLVGIDFLAVMGFASAISVIFAVFSALTLLPALISIFHKRI
                     KVNKLQSNFKKDIDTPWSKFITGNALAAVLLGLIILVAAAIPVSHMRLGIPDDGVKPA
                     DSTQKKAYDIISDKFGEGFNGQIPMLINVKDKKDDPQGLQQDLQSVYKDIKDKKNVDI
                     VTPPQMSKDNDYALMVVIPKQGPNAESTNDLVHDLRDYHKDAQDKYGFKTEISGQSVI
                     NIDMSKKLNEAIPLFATVIVVLAFFLLMIVFRSILIPLKAVLGFVLSLMATLGFTTLV
                     MQDGFMKGLFGIETTGPMLAFLPVITIGILFGLAMDYEVFLMSRIHEEYSKTGDNDYS
                     IKVGLKESGPVIVAAALIMFSVFFAFVFQEDVMIKSMGMALAFGVLFDAFVVRMMLIP
                     ALTKLFGKGSWYLPAWLNRIIPRVDIEGHALEKYKTVESQESEAKDSKETYDTTFKVY
                     PQGATNVSKHQDVHGQDDAHSIVLDDKTMALYQEVKQQSASSLFLYDALIDYQNKHQL
                     NSKQQVTNIEQLNKNIEKLNQLLEKNLRNKS"
     gene            11655..12203
                     /gene="farR"
                     /locus_tag="RFE25_002342"
     CDS             11655..12203
                     /gene="farR"
                     /locus_tag="RFE25_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid efflux pump transcriptional regulator
                     FarR"
                     /protein_id="HDU2817378.1"
                     /translation="MKETDLRVIKTKKPLSSSLLQLLEQQLFQTITVNQICDNALVHR
                     TTFYKHFYDKYDLLEYLFNQLTKDYFARDISDRLNHPFQTMSDTINNKEDLREIAEFQ
                     EEDAEFNKVLKNVCIKIMHNDIKNNRDRIDIDSDIPDNLIFYIYDSLIEGFIHWIKDE
                     KIDWPGEDIDNIFHRLINIKIK"
BASE COUNT         4070 a         2296 c         1912 g         3955 t
ORIGIN      
        1 taaacgtcgc gcacaagtcg gcaaacctgt ttctaataga tggggcaatg ctaaaaattg
       61 gtattacaat gcacgtaaat caaaatatgc gactggtcgt acaccaagaa aatttgctgt
      121 catgcaatca actgcaggat attatggaca tgtcgcagtt gttgaacaag tatataaaaa
      181 cggtagtatt aaagtttcag aatacaactt ttatcgccca ttaaaataca atacacgtgt
      241 actaagcaaa aaggcagcac gtaactttaa ctatatttac taatcaaaaa acttctatca
      301 cgaacgcttc aatttcctgt atgcgtgtga tagaagtttt tattttttgt tcatattaat
      361 ttatctaagc gctacgatgg actgacttaa acttttcttt aaaatcgcta ttcgccattt
      421 actattgttg tctaatttct tgtaaaatgc gttcagctac ttgtgtattc gcacggggtt
      481 cttgcttcaa tgcttcagct acttgcgcaa tttcatcacc ttttgcacct acaacaatag
      541 ctaaagattt atattgcaag ctcatatggc cttgctggat accttcggaa acgagcgcgc
      601 gacatgctgc aaagttctgt gctaaaccaa cggcagcaac tacatgacct aattcttgtg
      661 ctgaatctac atttagcaat tctaaagaag ctttagcaat tggtaatact tttgtaccac
      721 cgccaacgat tgccaatgtc ataggcactt ctattgtacc aattaaacgt tgacgttttt
      781 gatcgtatct ccatgttgca ataccacgat actgtccgtc acgactcgcg tatgcatgcg
      841 cacttgcttc tgcaccacgc gtatcatttc ctgttgctaa aacaacggca tgtatgccat
      901 tcataacacc tttattatgt gttgcagcac gatgaatatc aacttgtgcc aatacagaag
      961 cacgttccat tcgtttggca acctcttctc cagttctctc gccccttgct aaatctttaa
     1021 cgtcaatttc gccttgaact ttaacaacgg acgctgttgc atgattggat aaaatactca
     1081 ttaaaatgtc gctttgtgga gattcatttt ttaaaaatgc agttatggcc tctaaaatcg
     1141 tattaagcat attagcgccc atagcatctt tcgtatcaac aaatactttt aaagatagta
     1201 actgttgctc aggaaatgta tcaatagcta tacgttggta accaccacca cgcgctttaa
     1261 tagaaggata tgcctcatcc gcaattttat gaatttgctt ttctaaagct ttaatgtctg
     1321 ctgataattt ttcagtatcg tcaacgccat caaagacgat ttgacctatc ataatacgtt
     1381 cagaagatac cgttttaaat ccgccagtct gattcactag ctttgcacca taactagctg
     1441 cagcgacaac tgaaggctct tccaccatca taggtacaac atatgcctta tcgtccacaa
     1501 tgatattcgg taataatcca acgggtaatg caccttgcgc gatgacattt tcaattaaac
     1561 tatttgctac ttcctcatca attaatggat gattcaataa aatgtcgaat tgatcttctg
     1621 ataaccattg cttatctacc aattgttgta acttttgttg acgagataaa tgtcggaaat
     1681 tcttatctaa actttgcatg gacatactcc ttttacttca cataattttt taacatttca
     1741 atcactacta tttttaccat aaaataacgt tattcgtctt aaaattcaat tgaataatta
     1801 ttgttttaac tataaaataa agcaaggtaa attaaaacgc ttacaagaaa cgtcaaatca
     1861 tttttaaatt tagtgtattt ctttgtataa gataagcata ttctgatatg atacaagtgt
     1921 tgcttttata aatttgaaag gatgtaaaac cttatgacaa taggtatcga caaaataaac
     1981 ttttacgttc caaagtacta tgtagacatg gctaaattag cagaagcacg ccaagtagac
     2041 ccaaacaaat ttttaattgg aattggtcaa actgaaatgg ctgttagtcc tgtaaaccaa
     2101 gacatcgttt caatgggcgc taacgctgct aaggacatta taacagacga agataaaaag
     2161 aaaattggta tggtaattgt ggcaactgaa tcagcagttg atgctgctaa agcagccgct
     2221 gttcaaattc acaacttatt aggtattcaa ccttttgcac gttgctttga aatgaaagaa
     2281 gcttgttatg ctgcaacacc agcaattcaa ttagctaaag attatttagc aactagaccg
     2341 aatgaaaaag tattagttat tgctacagat acagcacgtt atggattgaa ttcaggcggc
     2401 gagccaacac aaggtgctgg cgcagttgcg atggttattg cacataatcc aagcattttg
     2461 gcattaaatg aagatgctgt tgcttacact gaagacgttt atgatttctg gcgtccaact
     2521 ggacataaat atccattagt tgatggtgca ttatctaaag atgcttatat ccgctcattc
     2581 caacaaagct ggaatgaata cgcaaaacgt caaggtaagt cgctagctga cttcgcatct
     2641 ctatgcttcc atgttccatt tacaaaaatg ggtaaaaagg cattagagtc aatcattgat
     2701 aacgctgatg aaacaactca agagcgttta cgttcaggat atgaagatgc tgtagattat
     2761 aaccgttatg tcggtaatat ttatactgga tcattatatt taagcctaat atcattactt
     2821 gaaaatcgtg atttacaagc tggtgaaaca atcggtttat tcagttatgg ctcaggttca
     2881 gttggtgaat tttatagtgc gacattagtt gaaggctaca aagatcattt agatcaagct
     2941 gcacataaag cattattaaa taaccgtact gaagtatctg ttgatgcata tgaaacattc
     3001 ttcaaacgtt ttgatgacgt tgaatttgac gaagaacaag atgctgttca tgaagatcgt
     3061 catattttct acttatcaaa tattgaaaat aacgttcgcg aatatcacag accagagtaa
     3121 tctgtgtatt tgaaagacat ttaaatataa cctaaaaaca gcagtaagac agcttctcat
     3181 tgaaatcgtc ttactgctgt tctctattta taacacttcg tattgaatga attcattatg
     3241 cctatttgac acattattga aatttttaat atacccctta tacgttacgg ctttgtactg
     3301 tgtttaggta tataaagctt tgacatatcg atattctcca actctaacag cttaatttta
     3361 ttattaatcg ttccaccgaa tcctgttaag ctacccgttt taccgacaac acgatgacat
     3421 ggcacgataa ttgataatgg attacttccg actgcacctc caaccgcttg ggctgacatt
     3481 tttggcttat caagcacctt acctactttt ttggcaatag caccatacgt tgttagagtc
     3541 ccataaggaa cctgtcttaa ttcattccaa acacactgtt gaaaatgact acctgttggc
     3601 tttaaaggta ttgtgatttc aggattgtca cctttaaaat acgcgtctaa ccactgtgtc
     3661 gcctctctaa atatcgctaa agacgtattt tcttccctag taccatcacc ttgttgattt
     3721 tcaaacaaaa cagcggtcag acttacccca tcactcaaaa gttccaatcg tcttacaggc
     3781 gaatcatagt aactcttata ctccataaaa attccccctt tttctaatca tacgccttaa
     3841 ttgttaaatt agaaaatatt catgttcaca ttttttaaaa ataaataagt cgtcaattac
     3901 gtatataaac acgtaatacc agctatccct ttgctgcaat atacagttac ataacttact
     3961 acacgtgcta acctattact ttgtaaacca aatcttaaat taaaatattg aaaatgcaat
     4021 ggatccttaa tattttatta aacctataat tacttattaa aaataacaca caatattcat
     4081 aaagttttaa aaatattctg ttttatcacc tattattagt ggaaaagtac aattgcaatt
     4141 gtatatagtt tgcataacgc ttcaaaagta atttcttttt tgtttagttc aaaaaaattt
     4201 agaggtgatg ttatatgaat aacggttttt tcaatagcga ctttgattca atttttcgaa
     4261 gaatgatgca agatatgcaa ggttcaaatc aagtcggtaa caaaaagtac tatattaatg
     4321 gtaaagaagt ttcacctgaa gaactagcgc aactcacaca acaaggtagc aatcaatctg
     4381 ctgaacaaag tgcgcaagct tttcaacaag cagcacaaag acaacaaggg caacaaggtg
     4441 gcaacggcaa ttatttagaa caaattggtc gtaaccttac gcaagaagca cgtgacggtt
     4501 tattagatcc agtcattggt cgtgataaag aaattcaaga aactgctgaa gtcttaagta
     4561 gacgaactaa aaacaatcct atattagttg gagaagctgg tgttggtaaa actgcgattg
     4621 ttgaaggttt agcacaggca atcgttgaag gaaatgtacc agcagcaatc aaagacaaag
     4681 aaattatttc tgtagatatt tcatcattag aagctggaac gcaatatcgt ggtgcttttg
     4741 aagaaaatat tcaaaaatta atcgaaggtg ttaaatcttc acaaaatgcc gtactattct
     4801 ttgatgaaat ccatcaaatt atcggttcag gtgccacagg aagtgattca ggtagcaaag
     4861 ggttatctga tattttgaaa cctgcattaa gtcgtggtga gatttctatt attggtgcaa
     4921 caacacaaga tgaatatcga aacaatattc ttaaagatgc tgcattaacg cgcagattta
     4981 atgaagtgct tgttaatgaa ccaagcgcta aagatactgt tgaaatttta aaaggtattc
     5041 gcgaaaaatt cgaagaacac catcaagtaa aattaccaga tgacgtatta aaagcatgtg
     5101 ttgacttatc aattcaatat attccacaac gattattacc agataaagca atcgatgtgt
     5161 tagatattac agcagcacat ttatctgcgc aaagtccagc tgtcgataaa gttgaaactg
     5221 aaaaacgaat ttctgaatta gaaaatgata aacgtaaagc agtaagtgct gaagaatata
     5281 aaaaagctga cgacattcaa aatgaaatca aatcattaca agataaatta gaaaacagta
     5341 atggtgaaca tactgctgtt gctacagttc atgatatttc agatactatt caacgattaa
     5401 ctggcattcc agtttctcaa atggatgata acgatattga acgtttaaaa aatatttcta
     5461 atcgtttaag aagtaaaatc ataggtcaag atcaagctgt agaaatggtt tcacgtgcaa
     5521 ttcgccgtaa tcgcgctggg tttgatgacg gcaaccgtcc aattggtagt ttcttatttg
     5581 tcggccctac tggtgttggt aaaacagagc ttgctaaaca attagcaatt gatctatttg
     5641 gtaataaaga tgcacttatt cgacttgata tgagtgaata tagtgacaca acagctgttt
     5701 caaaaatgat tggtacaact gctggttatg tcggttatga tgacaattca aatacgttaa
     5761 ctgaaaaagt acgccgtaat ccatactcag tcattctatt tgatgaaatc gaaaaagcaa
     5821 atccacaaat tttaacattg ttattacaag taatggatga tggtaatttg actgatggtc
     5881 aaggtaatgt catcaacttt aaaaatacaa ttattatttg tacatcaaat gctggctttg
     5941 gcaatggcaa tgacgctgaa gaaaaagata ttatgcacga aatgaaaaaa ttcttccgcc
     6001 ctgaattcct taaccgcttc aacggcatcg ttgaattctt acatttagat aaagatgcat
     6061 tgcaagatat cgtcaactta ttattagacg atgtacaagt tacattagat aaaaaaggta
     6121 ttacgatgga cgtttctcaa gatgcgaaag attggttaat tgaagaaggc tatgatgaag
     6181 aattaggtgc acgtccatta agacgtattg ttgaacagca agtacgtgac aaaattacag
     6241 attattatct agatcataca gacgttaaac atgtggatat agatgttgag gataacgaat
     6301 tagtcgtaaa aggtaaataa cgacacttta acatatcgcg catcaaaaat gagcatcagg
     6361 tcgcccttgc ctgtgctcat ttttttaatt atttccctgg aaaatgattc gctgtgtgct
     6421 gttctattcc acaacaatca cgattaatgt cacatgtacc acattttcct tgtttcgaac
     6481 gcttgaaaaa ttttactagt gtatataagg catatccgaa aattgctaaa aaaattaaaa
     6541 tgttaataat gactgacact ttaaccactc cttaaacaaa taaatgtccg acttgataaa
     6601 aaatgaatgt taagacatat gcagtgacta gaggataggc aactgcaagt gccgtccatt
     6661 tccatgaata agtctcttta cggattgctg ccactgtaga aacacaagga atatacaata
     6721 gtataaatat cataaatgca tacgcagata gcggtgtgaa ttgattttga atcacattaa
     6781 caaggcctgc atcacctgat gaatagataa tcgccatcga acttacgata acttcttttg
     6841 ctaaaaatcc tggcactaac gtagcacctg cttgccatgt tccaaatccg agcggttgca
     6901 ctaacatgcc aaagaaacta ccaaccatat gtaaaaaact ttgattgata ttcacattga
     6961 taccatgtgg tcctacataa cttaatagcc aaatgactac tgagccgcca aaaataaatg
     7021 tacctgcttt acgaacaaag cccttagcct tttcccaagt actacgccac aacgttttaa
     7081 tggaaggcac acggtatgtt ggcaattcca caataaagat tgcattatca ttttttaaaa
     7141 tcgtcttagt aagtactgta ctgactaaaa atgccataat aatacctaaa acatacaggc
     7201 ttaatactac taaagattga ttctctttga aaaagatacc tacgaacaac gcatacactg
     7261 gcagtctagc agagcatgac atgaatggtg caattaatat cgttgttaaa cgctcttttt
     7321 cattttcaat actgcgcgca gccataatac tcggtacatt acaaccaaat ccgataatca
     7381 ttggtataaa agacttcccg cttaaaccga acgattccat aatacgatcc attaaaaccg
     7441 caatacgtgc catataacct gaatcttcta ataaagatat aaagaaaaag agcacaacaa
     7501 tttgtggtac aaagactaat actgatccta caccagcaat aatgccatct gtaattaaat
     7561 cttgtaaaaa tggtataacc cctagataat tcataatcgt cttcacacta tctgtaaatg
     7621 taccacctat aaatgcatcg agttgatccg acaaaggtgt gccaatccat gtaaatgtag
     7681 tttgaaagat caaccacata attgctagaa agataggcat ccctatatat ttatgtgtta
     7741 atatcttgtc tattctagag ctgaaatatt gcttatcttc atctggatac gttaccacgt
     7801 cttgcaataa cgtctcaata taatgattgc gtatacgctc catctctcga cgaacagata
     7861 cagcccctac ttgttcagca acttgatcac gtaaactcga caatttattt acaacctctg
     7921 aattaagttc gtttgcaatt tgcatgttat ttaataagaa ttgaatcgca ataaacctag
     7981 cttgatactt atcatgagat gtctctgtca ttattatttg acacatattt ttaattgtct
     8041 cttcaatctt ctcaccataa ttgattttaa aatgcggttg atacccttcc cctagatgct
     8101 ttatttcgcc aagtaaatat tttgttcctt tgcctgtacg tgccacaact ggaaaaatag
     8161 gtgtttttaa ctttttcatc aatttatgat aatcgatttt tatcccgcgc tttgtagcta
     8221 catcaatcat atttaatccg atgtatattg gttgattaag ttctaacaat tgtactgtta
     8281 attgcacatt tctttttagt tgactcgcat caacaatgtt aatgattcct gaaaatgaat
     8341 cgtttaataa atagtctgtc actacagttt catctttaga aatcggcgat aaatcatatg
     8401 tacctggtaa atcaattaat tgtcctacat tttctttaag tttccctact tttttctcta
     8461 ccgttacgcc actccagttg cctatatatt catacgaacc agttaaagcg ttaaacaaag
     8521 atgttttacc aacattagga tttcctaaaa tacaataatt ttccattcgt ccggctccta
     8581 ttcttctaat gcaatagaac aagcatcgca atgtctaata cttaactgtt gtccgtttac
     8641 ttcaataata catggccctt taaataaaca tttttgttta atcgttatga tagcgtcatc
     8701 tgttaaccca aaggcactta gacgatacaa catattctca ttagcaatat ccattcgctt
     8761 tattttataa gccttattca tttcaccatt tttaatgttt aacatactat ttcgctctcc
     8821 tattagaaat aataatcatt atcacttaaa aatcataacc cttaaaattg tagctcgcaa
     8881 tactttattt aaataatttt catttttcat gtaaaatttg cgacattgca aaaatgtttt
     8941 gtataatcac ttccatgcaa aaaacctccg cttcaaatgt cattgataga catttaaagc
     9001 ggaggcatgt acatgttatt ttatgattta tttcgtagat ttttttctaa caattgattg
     9061 agcttttcaa tatttttatt caactgttct atattcgtta cttgttgttt tgaatttagt
     9121 tgatgcttgt tttgataatc tattaaagca tcatataaga acaatgaact tgcagattgc
     9181 tgtttcactt cttggtacaa tgccatcgtt ttatcatcta gtactattga atgtgcatca
     9241 tcttgcccat gtacatcttg atgtttcgat acatttgttg caccttgtgg atatacttta
     9301 aaggttgtgt cgtatgtttc cttactatct ttggcttcag attcctgtga ttcaaccgtt
     9361 ttatattttt caagtgcatg tccttcaata tcaactcgtg gaataatgcg attcaaccat
     9421 gctggtaaat accacgaacc ttttccaaac aatttcgtta atgcaggaat taacatcatt
     9481 ctgactacga aggcatcaaa gagtacacca aacgctaatg ccatacccat tgatttaatc
     9541 atgacatctt cttggaatac aaacgcaaag aagacactaa acataattaa tgcagcggct
     9601 acaataacag gaccgctttc tttcaatcct actttgatag aataatcatt atcccctgtt
     9661 ttactatatt cttcatgaat tcgcgacata aggaagactt cataatccat cgctaatcca
     9721 aataagatac ctatagtaat aaccggtaaa aatgctagca ttggtcctgt cgtttcaata
     9781 ccaaacagac ctttcataaa accatcttgc attactaatg ttgtaaatcc tagcgttgcc
     9841 attaatgaca agacaaatcc taaaactgct tttaacggta ttagaattga acggaagaca
     9901 atcattaata agaaaaatgc caatacaaca attactgttg caaataaagg tatcgcctca
     9961 tttaactttt tagacatatc aatattaatg acactttgtc ccgaaatctc cgttttgaac
    10021 ccatatttat cttgtgcatc tttatgataa tctcgtaaat catgcactaa atcatttgtg
    10081 ctctctgcat taggcccttg cttaggtatc acgaccatca aagcataatc attatcttta
    10141 ctcatttgtg gcggcgtaac gatatctaca tttttcttat ctttaatatc tttatataca
    10201 gactgtaaat cttgttgtaa tccttgtgga tcatcttttt tatctttaac atttatcaac
    10261 atcggaattt ggccattaaa tccttcacca aatttatccg agattatatc gtaagctttt
    10321 ttctgtgtag aatctgctgg tttaacaccg tcatctggaa taccaagtcg catatgacta
    10381 actggtattg cagctgctac taatatgatt aaacctagta atactgccgc aagtgcattt
    10441 cctgtaataa atttagacca cggcgtatca atatcttttt taaaattaga ctgcaatttg
    10501 ttcactttaa tgcgtttatg gaaaatacta attaacgcag gtaataaagt cagtgcactg
    10561 aatacagcaa atataacact aattgccgaa gcaaacccca tcactgctaa gaaatctatg
    10621 ccaactagcg ataaaccaca tacggcaatc acaactgtca caccagcaaa aacaactgca
    10681 ctacctgctg ttcctattgc aagaccaatg cctttaatgt aatctgtttc agttttcata
    10741 acttgtcgat acctgaataa aataaacaaa gcataatcga taccaactgc tagtccaatc
    10801 attacggcta atgtcaatgt gacatttggt atatcaaatg cataagttaa caaactgata
    10861 atacctacac cagaggctag accaatcaat gcacttataa ttggtaatcc tgcagcaatg
    10921 actgaaccga atgtgattaa cagtacaaca aatgcaacaa taataccaac tagttcagaa
    10981 ttaccgccta cttctgtaga tgtcattcct gtaccagtta actctgtttg tacattatga
    11041 ttgtcacgta agtctttcaa atgactttta acattatctc tagagccatc ttttaaagat
    11101 gtttgactaa cgtcatatgt gatatctgca aatgcagttg ttttatcttt actaatttgc
    11161 ttattttcat atggatctga tattttatca atgtgcttgt catctttttt tatatcctct
    11221 aatgttttct taatgtcttc tgtaatgttc ggttgcacaa taccatcatc tttagtcgtc
    11281 ttaaagacaa cacgtatttg tgccttttca ctatcttgat taaaatgttt ttcaatcttt
    11341 ttattcgtat ctaacgactc taatcctgtc attttaatat cattgtcaaa tttcggtgca
    11401 tttgtagcaa gtggtatcaa tattgcagct acaatcacta tccatgcaat gaccgcggac
    11461 catttatgtt ttgcgatgaa tgtccccatc ttatataaaa attttgccaa agtatattgc
    11521 ctccttttaa aatcaacgtt atagtttaaa tatacagtgt agattattgt tcgattatag
    11581 tatctatccc cgacctctta aagaatcaat tggaaaattt tgtatattaa actacacaca
    11641 aaggagaaat gtagatgaaa gagactgatt tacgagttat aaagacaaaa aaaccattgt
    11701 cgagtagctt gctacaattg ttagaacagc aattattcca aacgattact gtcaatcaaa
    11761 tttgcgacaa tgcactcgta caccgcacaa cattttataa acatttttat gataaatatg
    11821 atcttctaga gtatttgttc aatcaattga ctaaagacta ctttgctaga gatatcagtg
    11881 accgtcttaa tcatccattc caaacgatga gtgatacgat taataataaa gaggatttga
    11941 gagaaatcgc agaattccaa gaagaagacg ctgaatttaa taaagtatta aaaaatgtct
    12001 gcattaaaat tatgcataac gatatcaaaa ataatagaga ccgtatcgat attgacagcg
    12061 acatcccaga taatctcata ttttatattt atgactcgtt gattgaaggt tttatacatt
    12121 ggataaaaga tgaaaaaatt gactggcctg gcgaagatat tgataacatt ttccatagat
    12181 taatcaatat taagattaaa tagtagatga gaaactcatg agcgttacca aca
//
LOCUS       DAPDIM010000074        11976 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000074 DAPDIM010000000
VERSION     DAPDIM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 11976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11976
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.074"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            201..1631
                     /gene="eap"
                     /locus_tag="RFE25_002343"
                     /gene_synonym="map"
     CDS             201..1631
                     /gene="eap"
                     /locus_tag="RFE25_002343"
                     /gene_synonym="map"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001623710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular adherence protein Eap/Map"
                     /protein_id="HDU2817379.1"
                     /translation="MKFKSLITTTLALGVIASTGANFNTNEASAAAKPLDKSSSTLHH
                     GHSNIQIPYTITVNGTSQNILSSLTFNKNQNISYKDIENKVKSVLYFNRGISDIDLRL
                     SKQAEYTVHFKNGTKRVIDLKSGIYTADLINTSDIKAISVNVDTKKQPKDKAKANVQV
                     PYTITVNGTSQNILSNLTFNKNQNISYKDLEGKVKSVLESNRGITDVDLRLSKQAKYT
                     VNFKNGTKKVIDLKSGIYTANLINSSDIKSININVDTKKHIENKAKRNYQVPYSINLN
                     GTSTNILSNLSFSNKPWTNYKNLTSQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGG
                     KRILQLNSKNYTANLVHAKDVKRIEITVKTGTKAKADRYVPYTIAVNGTSTPILSKLK
                     ISNKQLISYKYLNDKVKSVLKSERGISDLDLKFAKQAKYTVYFKNGKKQVVNLKSDIF
                     TPNLFSAKDIKKIDIDVKQYTKSKKK"
     gene            1646..1936
                     /locus_tag="RFE25_002344"
     CDS             1646..1936
                     /locus_tag="RFE25_002344"
                     /inference="COORDINATES: protein motif:HMM:NF015598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAP domain-containing protein"
                     /protein_id="HDU2817380.1"
                     /translation="MKFPVTINKFENIVSNEFVFYNASKITINDLSIKLKSAMANDQG
                     ITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDERVFKATDIKKVDIELKF"
     gene            complement(2215..3501)
                     /locus_tag="RFE25_002345"
     CDS             complement(2215..3501)
                     /locus_tag="RFE25_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDU2817381.1"
                     /translation="MNPLAQSLNEQLQQSNATAFTMLSDLGQNMFYPKGILSQSAEAK
                     STTYNATIGMATNKDGKMFASSLDAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRD
                     NPELSIDNMSLPIVTNALTHGLSLVGDLFVNQGDTILLPEHNWGNYKLVFNTRNGANL
                     QTYPIFDKDGHYTTDSLVEALQSYNKDKVIMILNYPNNPTGYTPTHKEVTTIVDAIKA
                     LADKGTKVIAVVDDAYYGLFYEDVYTQSLFTALSNLNSNAILPVRLDGATKEFFAWGF
                     RVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQN
                     IQTLKERYEVTKEVVYADQYHSHWQAYDFNSGYFMAIKVHDVDPEELRKHLIEKYSIG
                     VIALNATDIRIAFSCVEKEDIPHVFDSIAKAIDDLR"
     gene            3701..3799
                     /locus_tag="RFE25_002346"
     CDS             3701..3799
                     /locus_tag="RFE25_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817382.1"
                     /translation="MMWWQEGMMTLITGGLLIIFRLWLELKWKNKK"
     gene            4042..4218
                     /locus_tag="RFE25_002347"
     CDS             4042..4218
                     /locus_tag="RFE25_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817383.1"
                     /translation="MKHLTKIFVVLAIILFIIGYYLQATNHESQGIKLLLAAIMFMIC
                     AFISRSNDRRKNSK"
     gene            4476..4856
                     /locus_tag="RFE25_002348"
     CDS             4476..4856
                     /locus_tag="RFE25_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDU2817384.1"
                     /translation="MKIILKNNSDFPIYEQIKQQVKQNILKGHVAPGEHLPSMRELAK
                     DLQVSLITTKRAYEDLEKDGFVTTIRGKGTFVKEQDSSILKEKQFFTIENLVKELVNE
                     AQAIEMSLEELQDILTFIYEEESS"
     gene            4853..5749
                     /gene="pmtA"
                     /locus_tag="RFE25_002349"
     CDS             4853..5749
                     /gene="pmtA"
                     /locus_tag="RFE25_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     ATP-binding protein PmtA"
                     /protein_id="HDU2817385.1"
                     /translation="MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTI
                     IRLIMDLYQPQTGVIRVLEEDMALNPIELKNSIGFVYSENYFNERWTTKQLEKMIAPF
                     YRKWDHQVFEFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLD
                     PLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQ
                     RYQVVSGATEDLDDELASLLIYEEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENL
                     MVYLEKRKPKYHENIKLIEEGF"
     gene            5750..6430
                     /gene="pmtB"
                     /locus_tag="RFE25_002350"
     CDS             5750..6430
                     /gene="pmtB"
                     /locus_tag="RFE25_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     permease subunit PmtB"
                     /protein_id="HDU2817386.1"
                     /translation="MKALLIRNFKLRRYTLIIYVLLLTLYPFYIMLDSTKFFYLLQSF
                     ISPTILIIWILDAGHLFRLNRRLGGNDSYYFYMSLPVSKKQLLNANYITCIVLTLIGT
                     LVISLYAYEADVIEPNSIYFSTAYAFVISNFLSIPIAFSQFTELRRVKVPYGIYVFTI
                     IILVPFLFSIAIVLVNYFVLSQSSFPDLYSYILNIGFLIISIVILIVNYFKQLNKINT
                     RKFKGGSR"
     gene            6427..7299
                     /gene="pmtC"
                     /locus_tag="RFE25_002351"
     CDS             6427..7299
                     /gene="pmtC"
                     /locus_tag="RFE25_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     ATP-binding protein PmtC"
                     /protein_id="HDU2817387.1"
                     /translation="MKLEHITKKYGSNVVLNDIDFDFGDSRIVGLIGKNGVGKTTIMK
                     VMNGNIIKFDGKVDIDNADNIGFLIEHPKLYDNKSGLYNLKLFAQVLGKGFDKAYTDK
                     IIDAFGMRPYIKKKVKKYSMGMKQKLAIAVSLMNKPKFLILDEPTNGMDPDGSIDVLT
                     TIKSLVNELDMRILISSHKLEDIELICDRAVFLRDGHFVQDVNMEVGVASDTTIVTVD
                     HKDFDRTEKYLAEHFQLQNVDKADGHLMINAQKNYQVILKALSELDIYPKYIETRKSS
                     LRDTYFNINQRGDK"
     gene            7299..8039
                     /gene="pmtD"
                     /locus_tag="RFE25_002352"
     CDS             7299..8039
                     /gene="pmtD"
                     /locus_tag="RFE25_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     permease subunit PmtD"
                     /protein_id="HDU2817388.1"
                     /translation="MRILNLVKYDFYSIFKSPLTYLAILVVSSLIATQSILMANSMDN
                     PKHIIVYGSVFAAAKWLLLIIGLMFVVKTITRDFSQGTIQLYMSKVKTRVGYIISKTI
                     SIILISILFALIHYVILIVVQASSNGKNLAFSKYVDNLWFFLIFLLFFGLFLFLITLA
                     SQKTAMIFSLGVFLVLIVPFIKPFITFIPRYGEKVLDAFDYIPFAYLTDKMISSNFDF
                     SNWQWVISLGSIVIFFILNILYVAKKDI"
     gene            complement(8105..8668)
                     /locus_tag="RFE25_002353"
     CDS             complement(8105..8668)
                     /locus_tag="RFE25_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDU2817389.1"
                     /translation="MTNLETYFKNSQPLNEYIDGMKTNQDTVLSIYQSFELPEDDSRI
                     KKIKEMNYSKVLVITEDWCGDAMMNLPILKHISEALNLEVRVFHRDDDTKLIDQYLTN
                     GKSRAIPIFVFLNDQFEQETVWGPRANEVQKFVTDVRADKLPSKDHPDYADLEKETHL
                     VISNRYKTDASFWKAVYNSILNKLENK"
     gene            8789..9313
                     /locus_tag="RFE25_002354"
     CDS             8789..9313
                     /locus_tag="RFE25_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817390.1"
                     /translation="MLYLNKYKERVTSVRIQNRWVVFILFLICSFGVLIGLYQYRHTK
                     TVDLSNLEINDIKLNEKFDKKGYEVNKKIKFDRFKFYNSKAHPDLTVKVREKDNIVKG
                     IILVRDEKIHTNFDGGIGSPINNAIENLGFGYKRTKVGNDFSSVKYIDRDNHLKLNLL
                     YQDLEIKRIEFFSK"
     gene            9373..9930
                     /locus_tag="RFE25_002355"
     CDS             9373..9930
                     /locus_tag="RFE25_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDU2817391.1"
                     /translation="MNKITYLNELETALDALPRHLRDQKMYEYERYFYEQELNGVDEG
                     EILKKLKDPQDVAAETKARSVIDYAESKPTFENISRAVAASLSLGILSIFVILIPVSI
                     VGLFVLALFLISLLLLFCPIILLASAISRGIVDSISNVFFAISYSGLGLVFIIVIFKI
                     LEYIYRLILKYLLWYIKTVKGSVRK"
     gene            9927..10769
                     /locus_tag="RFE25_002356"
     CDS             9927..10769
                     /locus_tag="RFE25_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDU2817392.1"
                     /translation="MKKFFFIGLLVFVVFFTAATIIWFSYDKNKYGTKQYDKTFKDDA
                     FDNVSINLDSTELRIKRGNQFRVKYDGDNDILINIVDKTLKISDKRSKTRGYAIDMNP
                     FHENKKTLTIEMPDKMIKRLNLSSGAGSVRISDVDLENTSIQSINGEVVIKNSNLDAL
                     DSKTNNSSTYISKSNIKNSNIKVVIGTLQIDKSQIKQSIFLNDHGDIEFKNMPSKVDA
                     KASTKQGDIRFKYDSKPEDTILKLNPGTGDSVVKNKTFTNGKVGKSDNVLEFYTIDGN
                     IKVE"
     gene            complement(10826..11866)
                     /locus_tag="RFE25_002357"
     CDS             complement(10826..11866)
                     /locus_tag="RFE25_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDU2817393.1"
                     /translation="MQQVISDIMTFRGSHFELGVKTGKWLQQTPLLKNREKEWKKRVP
                     RFDIDVNETYQIFQTYAPQIWEELMGLQSILKMPTRQIILNFGHYRFTDLKESGCTVF
                     QGKDFMVRNYDYHPATYDGRYLLYQPTDSGLAQIGPVSRVTGRMDGMNESGLTMGYNF
                     MHRKKPANGFVCYMIGRLILENCRNVTEAIQLLKEIPHRSSFSYILMDKSLNHAIVEV
                     TPRSIDVRYDNICTNHFEILTHENRNYTKESKERLARTISQTNDNLDMTTAFKLFNNP
                     QYEIYSKLFKSWSGTIHTSMYQPETLTAYFTLGENAPPEIIDFKSWLDGQDLNITHFT
                     GNIDTDLTFANK"
BASE COUNT         4298 a         1568 c         1960 g         4150 t
ORIGIN      
        1 acttggtata aacaaaatca aacaacattt taggtattgt aaattagtta gttaatcaaa
       61 attaaaagaa cttttaacag tgttaaaaaa ttattgttaa agataattta ttattaatat
      121 tcagttaatt caaaaaatag agaaagtctg gctataataa agttgcaatc acgaattaca
      181 taaaaaagga gagataattt atgaaattta agtcattgat tacaacaaca ttagcattag
      241 gcgttatagc atcaacagga gcaaacttta atactaacga agcatctgcc gcagctaagc
      301 cattagataa atcatcaagt acattacacc atggacattc taacatccag attccatata
      361 caattactgt gaacggtaca agccaaaaca ttttatcaag cttaacattt aataagaatc
      421 aaaatattag ttataaagat atagagaata aagttaaatc agttttatac tttaatagag
      481 gtattagtga tatcgattta agactttcaa agcaagcgga atatacggtt cattttaaaa
      541 atggaacaaa aagagttatc gatttgaaat caggtatcta cacagctgac ttaatcaata
      601 caagtgacat taaagctatc agtgttaacg tagatactaa aaagcaacct aaagataaag
      661 ctaaagcaaa tgttcaagtg ccatatacaa tcacagtgaa cggcacaagc caaaacattt
      721 tatcaaacct aacatttaat aaaaatcaaa atattagtta caaagattta gagggtaaag
      781 ttaaatcagt tttagaatca aatagaggta ttactgatgt tgatttaaga ctttcgaagc
      841 aagcgaaata tacagttaat tttaaaaatg gaacgaagaa agttatcgat ttgaaatcag
      901 gtatttacac agcgaattta atcaattcaa gtgatattaa aagtatcaat attaacgtag
      961 atacaaaaaa acatatcgaa aataaagcta aaagaaacta tcaagttcca tattcaatta
     1021 atctaaatgg tacatctaca aacattttat cgaatctttc attttcaaat aaaccttgga
     1081 caaattacaa aaatttaact agtcaaataa aatcagtact gaagcatgat agaggtatta
     1141 gtgaacaaga tttaaaatat gctaagaaag cttattatac tgtttatttt aaaaatggtg
     1201 gtaaaagaat cttacagtta aattcaaaaa attacacagc aaacttagtt catgcgaaag
     1261 atgttaagag aattgaaatt actgttaaaa caggaactaa agcgaaagca gacagatatg
     1321 taccatacac aattgcagta aatggcacat caacaccaat tttatcaaaa ctaaaaattt
     1381 cgaataaaca attaattagt tacaaatatt taaacgacaa agtgaaatct gtattaaaaa
     1441 gtgaaagagg tatcagtgat cttgacttaa aatttgcgaa acaagcaaaa tatacagtat
     1501 atttcaaaaa tggaaagaaa caagtagtga atttaaaatc agacatcttt acacctaatt
     1561 tatttagtgc caaagatatt aaaaagattg atattgatgt aaaacaatac actaaatcaa
     1621 aaaaaaaata aataaatcta ataatgtgaa attcccagta acaataaata aatttgaaaa
     1681 catagtttca aatgaatttg tgttctataa tgcaagcaaa attacaatta atgatttaag
     1741 tataaaactt aaatcagcaa tggcaaatga tcaagggata actaaacatg acataggact
     1801 tgctgaacgc gcagtgtata aagtgtattt taaaaatggt tcgtcaaaat atgtagactt
     1861 aaaaactgag tataaagatg aaagagtatt taaagcaact gacattaaaa aggtagatat
     1921 tgaacttaaa ttctaatctt taattttata ataaggcatc tcacaatcgt ggggtgcctt
     1981 ttacatttgt agagatgtga tgcttgaatg tttgaagtga tttgccaaaa gttatataaa
     2041 tttgtaccaa ataaattaaa ttttgttagg agagatgtat aaaactaatt aggtatagtg
     2101 tttgacaagt tgctgaataa aatatatctt atgatacttt gaaagaagga ataattttaa
     2161 aaataaaaaa ccaataatcc gagtcatact catcagatta ttggttgaaa ttaattatct
     2221 taagtcatca atcgctttag caattgaatc aaatacatgt gggatatctt ctttttctac
     2281 acagctaaac gcaatacgaa tatctgttgc attaagtgca ataacaccaa ttgaatattt
     2341 ttcaattaaa tgtttacgaa gttcttcagg gtcaacatca tgaactttta ttgccataaa
     2401 gtatccagag ttaaagtcat aggcttgcca atgtgaatga tattgatcag catagacaac
     2461 ttccttagtg acttcatagc gttcttttaa tgtttgaata ttttgttcga tttctttatc
     2521 gaattgttta ttatttttta atacatgctt aacagcgctt tgtgttggaa gaggtccact
     2581 agaaatgtta cttcgtataa gaccttttac tttggcttct aatacttctt tagttgtttg
     2641 atcagacgtt ccaaatgtca taaacccaac acggaatccc catgcgaaaa attcttttgt
     2701 tgcaccatct aaacgaacag gtaatattgc atttgaattt aaattagata atgcagtaaa
     2761 taatgattga gtatacacat cttcatagaa taaaccatag tatgcgtcat ccacaacagc
     2821 tataactttt gtacctttat cagctaatgc tttaattgca tcgacgatgg tagtcacttc
     2881 tttatgcgta ggtgtgtaac ctgtcggatt attaggataa tttaaaatca taatgacttt
     2941 atctttattg tatgattgta aagcttctac aagtgaatca gtagtataat gcccgtcttt
     3001 atcaaagata ggatatgttt gaaggtttgc accatttctc gtattgaaaa caagtttgta
     3061 attaccccaa ttatgctctg gtaacaagat agtgtcacct tgatttacaa ataaatcgcc
     3121 aactaaagat aaaccatgtg ttaatgcatt cgtaacaatt ggtagtgaca tgttgtcgat
     3181 tgatagctct ggattgtcac gcaacatttt ttgttgccat aaatcacgta attcttcgat
     3241 gccttgtggt ggcgcataag ggaatatttc atctggagtt aaatcattaa acattgcatc
     3301 taaagatgat gcaaacattt ttccgtcttt gtttgtcgcc atacctatag ttgcattata
     3361 tgttgtactc tttgcttcag cagattgaga taaaatgcct tttggataaa acatattttg
     3421 acctaagtca gataacattg taaaggcagt tgcatttgac tgttgaagtt gttcatttaa
     3481 gctttgggct aaaggattca ttattgctta acctctcttt aaaaaaattg tatgcctata
     3541 tattatcttt aattatacca aagataaagt gttgttggtg aattaacgaa taatatgtaa
     3601 aatctgctgc caaaatacga acatatgttc tgtttttatg ttagaatagg tgtaggtcat
     3661 ccttcagtat gatactttag tcgaacggag gtgtagtgta atgatgtggt ggcaagaagg
     3721 gatgatgaca cttattacag gtggcttact aattattttt cgactttggt tagaactgaa
     3781 atggaaaaat aaaaaatgat cctacacaca taaataaccc caagtctgct ggtaccagac
     3841 ttggggttgt gtagtataat tctgtggata cacttaaata atatcattga acacaatata
     3901 tcgcaatcaa taatcatttt gattgaatgg ttttgttgcg ctattttagt tgaaagtgat
     3961 tagtaccttg aacttttgaa attcaataac ttattaaaaa aatttatatt tgttataatg
     4021 tcgatgttga ggtgaaataa attgaaacat ctaacaaaaa tatttgtagt acttgcaatt
     4081 attttattta ttattggtta ttatttacaa gcaactaatc atgaaagcca aggtataaaa
     4141 ttattattag cagcgattat gtttatgatt tgtgctttta taagtagaag taatgatcga
     4201 cgtaaaaata gtaaatagaa ttgactgttt aaaacgattg tttatgttga cgctacggtt
     4261 gtcacgtaga gattaaagac attcgtttta gcagtctttt ttattgaagt agacaatgca
     4321 agattaaatg gtagtgtcat ttcattttat tcaactgcta gtaatacaat actcagtgtt
     4381 atttctgaag actggttgat aatggacatg catatttaca aaactgtgta tattgtgtat
     4441 attgtatata tacagaagtt gataggggga cgttgatgaa aataatttta aaaaacaata
     4501 gtgattttcc gatttatgaa cagattaagc aacaagtaaa acaaaatatt ttaaagggac
     4561 atgttgctcc tggagagcat ttgccgtcaa tgagagaact tgccaaagat cttcaagtaa
     4621 gtttgattac taccaaacgt gcttatgaag atttagagaa agacggtttt gttacaacaa
     4681 ttagaggaaa agggaccttt gttaaggagc aagatagttc tattttaaaa gagaaacaat
     4741 tttttaccat tgaaaatttg gttaaagaat tggttaatga agcgcaagcc atcgaaatgt
     4801 cacttgagga acttcaagat attttaacgt tcatttatga ggaggaatca tcatgaatgc
     4861 catagaatta agtaatgtta attattcaag tgatcagttt aatttaaaga atatctcttt
     4921 caaagttcct caaggattcg tcactggttt tattggtaga aatggcgctg gtaaaaccac
     4981 aataataagg ttaattatgg atttgtatca accacaaact ggtgttatta gagtattaga
     5041 agaggatatg gctctcaatc cgatagagtt aaagaatagt attgggtttg tttactctga
     5101 aaattatttt aatgagagat ggactacgaa gcaacttgaa aaaatgattg ccccttttta
     5161 tcgtaaatgg gaccatcaag tatttgaatt ttatcttgaa aagttcgatt taccaatcaa
     5221 taaatcaata aaaacatttt cgactgggat gaaaatgaaa ttatcactag cagttgcatt
     5281 ttcacatcat gctgaattgt atatttttga tgagcctact tcaggtcttg atcccttagc
     5341 tagaaatgag ctattggaga taattcagca agaattaatt gatgaaaata aaacaatatt
     5401 catgtcgaca cacattatct cagatttaga aaaaatagct gattatatca ttcacttaag
     5461 tgacggtgaa gttatcttaa atggttcaaa agaacaactg ttacaaagat atcaagttgt
     5521 gagtggtgca actgaggacc ttgatgatga attagcatct ctacttattt atgaagaaca
     5581 taagcgtacg ggatttatag gattaacaga acatgcgcaa gtatttaaag aaattttagg
     5641 tcataaagtg aatatcacta caccttctat tgagaactta atggtttatc ttgaaaagag
     5701 aaaacctaaa tatcatgaaa acatcaaatt gatagaagaa ggtttttaaa tgaaggcatt
     5761 gttaattagg aattttaaat tacgacgata tacacttatc atctatgttc tattattaac
     5821 cttatatcct ttttatataa tgcttgactc aacaaagttc ttttacctat tgcaatcttt
     5881 tataagtcca acaatattga ttatttggat tttagatgct ggtcacttat ttagactcaa
     5941 tcgtagatta ggtggtaatg attcatatta tttttatatg agtttaccag tgtcaaaaaa
     6001 acaattgctt aatgccaact atattacatg cattgtttta acattaattg gaacgcttgt
     6061 tattagttta tatgcttatg aagcagatgt gattgaacca aattcaatct atttttcaac
     6121 tgcatatgca tttgtcatat ctaacttctt gtctatacca attgcattta gtcaatttac
     6181 agaattgcgt agagtcaaag tgccatatgg tatatacgtg tttactatta tcattttagt
     6241 tccattttta ttttcaattg caatagtgtt ggtgaattat tttgttctaa gtcaatcatc
     6301 attcccagat ttatattcat atattttaaa tattggtttt ctaattatca gcattgttat
     6361 acttattgtt aattatttta aacagctcaa taaaataaat actagaaaat ttaaaggagg
     6421 cagtcgatga aattagaaca tattacaaaa aaatacggct caaatgtcgt tttaaatgat
     6481 attgattttg actttggcga tagtagaatt gtcggattaa taggaaaaaa cggtgttggt
     6541 aaaacaacca ttatgaaagt aatgaatggt aatattatta aatttgatgg aaaagtagat
     6601 attgataatg cagataatat cggtttttta attgagcatc ctaaattata tgataataaa
     6661 tcaggattgt ataacttgaa attatttgca caagtattag gtaagggttt tgataaagca
     6721 tacacagaca aaattataga tgcatttggt atgagacctt atattaaaaa gaaagttaag
     6781 aaatattcaa tggggatgaa gcaaaagtta gcaattgcag tatctttaat gaataaacct
     6841 aaatttttaa tcttggatga gcctacaaat ggtatggatc cagatggctc aattgatgtg
     6901 ctgactacaa ttaagtcttt agtaaatgaa cttgatatga gaattctaat atcaagtcat
     6961 aagttagaag atattgaatt aatttgtgat agagctgtat ttttaagaga cggacatttt
     7021 gttcaagatg taaacatgga ggtaggtgtt gcatctgaca caacgatagt tactgttgat
     7081 cataaagact ttgatagaac tgaaaaatat cttgcagagc atttccaatt acaaaatgtc
     7141 gacaaagcag acggacattt aatgatcaat gcacaaaaaa attatcaagt tatactaaaa
     7201 gcattatctg aattagatat ttatccgaaa tatattgaaa cacgtaaaag ttcattgcgt
     7261 gatacgtact tcaatataaa tcaaagaggt gataaataat gagaatttta aatttagtta
     7321 agtatgattt ttatagtata tttaaaagtc ctttaacata tttagcgata ctagtcgtat
     7381 ctagtttgat tgcaactcaa agtatactta tggcaaattc gatggataac ccgaaacata
     7441 ttattgtcta tggatctgta tttgctgcag caaaatggtt attgttaata attggattaa
     7501 tgtttgttgt taagacaatt acgcgtgatt tttcacaagg tacaattcaa ctatatatga
     7561 gtaaagttaa aacacgcgtt ggatacatta tttcgaaaac aatttcaatt attttaattt
     7621 caatattatt tgcattaatt cattatgtga ttttgattgt tgtgcaggca tctagtaatg
     7681 gaaaaaattt ggcgttttct aaatatgtag ataatttatg gttcttccta atctttttac
     7741 tattctttgg cttgttttta ttcttaatca cacttgcatc acaaaaaaca gcaatgatat
     7801 tttcattagg tgtattttta gtactcattg taccgtttat taaacctttt attacattta
     7861 tcccaagata cggtgaaaaa gttttagatg cttttgatta tatccctttt gcttacttaa
     7921 ctgataaaat gattagctct aactttgatt ttagcaattg gcaatgggta atttcattag
     7981 gttctatagt gatattcttc attttgaata tcttatatgt cgctaaaaaa gacatttaat
     8041 aaaaataatt ttgaggttgg gaattttaaa ttttcccaac ctcaaagttt gtcttattgt
     8101 aaatttattt attttctaat ttatttagga tggaattata aactgctttc caaaatgaag
     8161 cgtcagtttt atagcggttt gatataacta agtgtgtttc tttttctaaa tctgcatagt
     8221 ctggatgatc tttgctcggt aatttatcag cacgaacatc agttacaaat ttttggactt
     8281 catttgctct tggtccccaa actgtttctt gttcgaattg atcattcaag aatacgaaga
     8341 taggaattgc acgtgattta ccatttgtta aatattgatc gatcagtttt gtatcatcat
     8401 ctctatggaa cacgcgtact tctaaattta atgcttcact gatgtgtttt agaattggga
     8461 gattcatcat tgcatctcca caccagtctt cagtaattac taatacttta gaataattca
     8521 tctcttttat ttttttgatg cgtgaatcat cttctggtaa ctcaaatgat tgatagatac
     8581 tgagaacggt atcttgattt gtcttcattc catcaatgta ttcatttaag ggttggctat
     8641 ttttgaaata agtttctaaa tttgtcattg taaaaacctc ctttagcatt tacaacatta
     8701 taccaattta tagtaataaa aggtaatgaa ataaattaat tgcaaattct ttgttaattt
     8761 ttgttaagga tgaaacggga ggcaccttat gctatattta aataagtaca aagaaagggt
     8821 gacatcagtg cgtattcaaa atcgctgggt tgtgtttata ttatttttaa tctgttcttt
     8881 tggtgtatta attggtttat atcaatatcg tcatacgaaa actgtggatt tgtctaatct
     8941 tgaaataaac gatattaaat taaatgagaa gtttgataaa aaaggctatg aagtaaataa
     9001 aaaaattaag tttgatcgtt ttaaatttta taacagtaaa gctcaccctg atcttaccgt
     9061 taaagtgaga gaaaaggata acatcgttaa ggggataata ttagtaagag atgaaaagat
     9121 acatactaat tttgatgggg gaattggttc gccgataaat aacgcgattg aaaatcttgg
     9181 attcggatat aaaagaacaa aagttggcaa tgatttctca tcggtaaagt atattgatag
     9241 agataaccat ttaaaattaa acttacttta tcaagattta gaaattaaac gtattgaatt
     9301 ttttagtaaa tagctttagg tcttaaagtt ataaaaaacg aataaataat tttattggga
     9361 tgagtgacct atatgaacaa gattacttat ttaaatgaat tagaaacagc acttgatgcg
     9421 ctacctaggc atttaagaga tcaaaaaatg tatgaatatg aacgttattt ttatgagcaa
     9481 gaacttaatg gcgttgatga aggggaaatt ttaaagaagt taaaagaccc acaagatgtt
     9541 gcagctgaaa caaaagctag aagtgttatt gattatgctg aatctaaacc aacatttgaa
     9601 aatatttcaa gagctgttgc tgcttcatta agtttaggca ttctatctat ttttgtcatc
     9661 cttataccag tatctatagt tggattattt gtattagcat tatttttaat atcacttttg
     9721 ctgctgtttt gtccaattat tttattagca tcagcaatat ccagaggaat tgtagactca
     9781 attagtaatg tattttttgc catatcatat tcaggattag gattagtatt tatcattgtc
     9841 atatttaaga ttttagaata catttatcgt ttaatcttaa aatatttact ttggtatatt
     9901 aaaactgtca aaggaagcgt tagaaaatga agaaattctt ttttattggg cttttagtgt
     9961 ttgttgtctt ttttacagca gcaaccatta tttggttcag ctatgataaa aacaaatatg
    10021 gtactaaaca atatgataaa acattcaaag acgatgcttt tgacaatgta tctataaatt
    10081 tggatagtac agaacttcgt ataaaacggg ggaatcaatt tagagttaaa tatgatggtg
    10141 acaatgatat attaattaat atagtagata agacgttgaa gattagtgat aaaaggtcta
    10201 agacaagagg atatgcaatt gatatgaatc cttttcatga gaataagaaa acgttaacga
    10261 ttgaaatgcc tgataaaatg attaaacgtt taaatctatc atctggagca ggaagtgtta
    10321 gaatcagtga tgttgattta gagaacacaa gtattcaaag cattaacggt gaagtagtta
    10381 ttaaaaactc aaatcttgac gcactagatt caaagacaaa taatagttct acttatatta
    10441 gtaaaagtaa cattaaaaat agcaatatta aagttgttat tggtacgcta caaatcgaca
    10501 agagtcaaat taaacaatcc atatttttaa acgatcatgg tgacattgaa tttaaaaaca
    10561 tgccatcaaa agtagatgca aaagcttcta ctaaacaagg agatattcgt tttaagtatg
    10621 atagtaaacc tgaagacact atactaaagc taaatccggg aacgggtgat agcgtagtta
    10681 aaaataaaac atttactaat ggtaaagttg ggaaaagcga caatgtttta gaattttata
    10741 cgattgatgg taatatcaaa gttgaataaa taaaggatgt aagcaccgat attaggaagc
    10801 ataatttctc taatatcggt gttatttatt tgttggcaaa agttaagtcg gtatctatat
    10861 tgccagtaaa gtgagtgata ttaaggtctt gaccatctaa ccatgatttg aaatctatta
    10921 tttctggtgg cgcattttct cccaatgtaa aatatgcagt taatgtttca ggttgataca
    10981 ttgatgtatg gatggtgcca gaccagcttt tgaatagttt actgtaaatt tcatactgag
    11041 gattattgaa taacttaaat gctgtagtca tatctaaatt atcattagtt tgtgaaatgg
    11101 tacgcgccag tctttcttta gattcttttg tataattacg attttcatgt gttaatattt
    11161 caaaatgatt tgtacatata ttatcataac gaacatctat tgatctcggt gtcacttcaa
    11221 caattgcatg gttcaatgat ttgtccatca gtatgtagct aaatgagctt ctgtgtggta
    11281 tttctttcaa taattgtatt gcttctgtta catttcggca attttcaaga attagacgac
    11341 caatcatata acatacaaaa ccatttgctg gtttcttccg gtgcataaag ttatagccca
    11401 tagttaatcc tgactcattc ataccatcca ttcttccagt tacccttgat acaggaccaa
    11461 tttgagctaa accgctatct gtaggttgat atagtaagta gcgaccatca taagttgcag
    11521 ggtggtaatc ataatttcta accatgaagt ctttgccttg aaagaccgtg caaccacttt
    11581 cttttaaatc ggtaaaacga taatgtccaa agtttaaaat aatttggcgt gttggcattt
    11641 tgagtatact ttgtagtccc attaattctt cccatatttg aggtgcgtaa gtttggaata
    11701 tttgataagt ttcatttaca tctatatcga aacgtgggac acgttttttc cattcttttt
    11761 ctcgattttt tagaagaggt gtttgttgaa gccatttacc agttttaaca cctaactcga
    11821 aatgtgaacc tctaaaagtc ataatatctg atatcacttg ttgcatatca tcggcccctt
    11881 tctttttagt tgtaatatat tgtaaataaa tagtaatcgt atgtatattg aatgtcatgt
    11941 taaataaagt tatattttac taaatgaaat ataaaa
//
LOCUS       DAPDIM010000075        10596 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000075 DAPDIM010000000
VERSION     DAPDIM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10596
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.075"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..200)
                     /locus_tag="RFE25_002358"
     CDS             complement(<1..200)
                     /locus_tag="RFE25_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817394.1"
                     /translation="MKYKHFAIITLITGIVMLTAMYFVPFGYHKIPIFAGMAIIFTVY
                     FSNKKSIDETNIFSKKNRNKNK"
     gene            complement(433..1281)
                     /locus_tag="RFE25_002359"
     CDS             complement(433..1281)
                     /locus_tag="RFE25_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDU2817395.1"
                     /translation="MNHIEISKDVKIPVLGFGVFQIPQEQTAEAVKEAIKAGYRHIDT
                     AQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEDTIKSIERSLQRLNLDYLDL
                     VLIHQPYNDVYGSWRALEELKENGKIKAIGVSNFGVDRIVDLGIHNQIQPQVNQIEIN
                     PFHQQEEQVAALQQENVVVEAWAPFAEGKNQLFQNQLLQAIADKYNKSIAQVILRWLV
                     ERDIVVLAKSVNPERMAQNLDIFDFELTEEDKQQIATLEESNSQFFSHADPEMIKALT
                     SRELDV"
     gene            complement(1351..1767)
                     /locus_tag="RFE25_002360"
     CDS             complement(1351..1767)
                     /locus_tag="RFE25_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDU2817396.1"
                     /translation="MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDL
                     NWIYLVKNLRNAGVSIESLIEFCRLAQLPKNKNIQTQQKQILNKQLEELNENLKTIHD
                     ARDLLKYKIDNYDNHIAKINASDNHDDNVERLWERK"
     gene            2011..2178
                     /locus_tag="RFE25_002361"
     CDS             2011..2178
                     /locus_tag="RFE25_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817397.1"
                     /translation="MRKIWVIDRLYASTFFVDCLTVDSHLYTLTNFENLNHYLIILLI
                     AHAQHKKETCQ"
     gene            2175..4604
                     /locus_tag="RFE25_002362"
     CDS             2175..4604
                     /locus_tag="RFE25_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide lyase 8 family protein"
                     /protein_id="HDU2817398.1"
                     /translation="MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNV
                     QTPDYEKLRNTWLDVNYGYDKYDEKNDAMKKKFDATEKEAEKLLSSMKTESGRTYLWD
                     SAKDLDNKSADMTRTYRNIEKIAEAMRHPKTTLNTDENKKKVKDALEWLHKNAYGKEP
                     DNKVKELTENFKITDSSKKKALNWWDYEIGTPRSLTNTLILLNDQFSNEEKKKFTAPI
                     KTFAPKSDEILSSVGKAEPAKGGNLVDIAKVKLLESIIEEDKDMMKNSIDSFNKVFTY
                     VQDSATDKERNGFYKDGSYIDHKDVPYTGAYGVVLLEGISQMMPMIKETPFNDKTQNN
                     TTLKSWIDDGFLPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDST
                     KAKYKKIVKTSVKSDSSYGQNDTLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMD
                     RVTYHNKDLDFAFGLSMTSKNVARYESINGENLKGWHTGAGMSYLYNSDVKHYRDNFW
                     ATADMKRLAGTTTLENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAK
                     KSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTASDNQGTNSV
                     FLESTNKPKNNIGYHFLNESKITVKKESHTGKWSDINKSQKQDSKTNQYYEVTQKHSN
                     TDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVKDNESVWAGVNYSNSTQTFDI
                     NNTKVEVKAKGMFILKNKDDNTYECSFYNPESTNTASDIESKISITGYSITNKNTSTS
                     NESGVHFELTK"
     gene            complement(4664..5518)
                     /locus_tag="RFE25_002363"
     CDS             complement(4664..5518)
                     /locus_tag="RFE25_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDU2817399.1"
                     /translation="MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWQFRKLFKSYTR
                     QSDVHELKVCTQNDDTMEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETT
                     LKYAVPTTDCYEVFWGGDNELYNYHYLYLHQRYAIDLVIKENHKTYKNQGKVNTDYFC
                     FGKDIIAPANGTVEKVVNGVQDNSIGSTNESQFLGNYIVIKHAENEYSLIAHLQQYSI
                     IVNEGQNVKYGDFLGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFLNNLELIKGD
                     VVCGLQGE"
     gene            complement(5729..6544)
                     /locus_tag="RFE25_002364"
     CDS             complement(5729..6544)
                     /locus_tag="RFE25_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HDU2817400.1"
                     /translation="MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVI
                     TAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEP
                     FLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDSRILEALVRYA
                     NDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDS
                     GNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY"
     gene            6839..7264
                     /locus_tag="RFE25_002365"
     CDS             6839..7264
                     /locus_tag="RFE25_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAP domain-containing protein"
                     /protein_id="HDU2817401.1"
                     /translation="MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKELTMDGK
                     HTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNELASQRGVTTEKINNAQTA
                     TYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK"
     gene            complement(7648..8352)
                     /gene="budA"
                     /locus_tag="RFE25_002366"
     CDS             complement(7648..8352)
                     /gene="budA"
                     /locus_tag="RFE25_002366"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDU2817402.1"
                     /translation="MTNVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNG
                     EVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEK
                     MLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFT
                     PELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIQDKDFTK
                     ANIDYKDIADEIREAE"
     gene            complement(8389..10053)
                     /gene="alsS"
                     /locus_tag="RFE25_002367"
     CDS             complement(8389..10053)
                     /gene="alsS"
                     /locus_tag="RFE25_002367"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDU2817403.1"
                     /translation="MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGP
                     ELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGG
                     QVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFI
                     SIPQDVISSPVESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSAEE
                     TNAIRKLVERTNLPVVETFQGAGVISRELENHFFGRVGLFRNQVGDELLRKSDLVVTI
                     GYDPIEYEASNWNKELETQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISEKVDEP
                     FINQQHLDELEQLRTHIDEETGIKATHEEGILHPVEIIESMQKVLTDDTTVTVDVGSH
                     YIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQ
                     DLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGL
                     RVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN"
     gene            10351..10575
                     /locus_tag="RFE25_002368"
     CDS             10351..10575
                     /locus_tag="RFE25_002368"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817404.1"
                     /translation="MRCLVNGGLKLSFYGGLKMLFYVGLEFVVLWRYKNAVLWRFQNG
                     VSINKPQQDLDLTMTYTFHTYISDYFYSYK"
BASE COUNT         3551 a         1790 c         1543 g         3712 t
ORIGIN      
        1 tgtttatttt tattgcgatt tttcttacta aagatatttg tttcatcaat agatttttta
       61 ttactaaaat agactgtaaa aataatcgcc attcctgcaa atattggtat tttatgatat
      121 ccaaatggta caaagtacat tgccgtgagc atgacgatgc ctgtaattaa agtaataatg
      181 gcaaaatgtt tatatttcat gttattatcc cctatacaat ttattctaca ttcattatat
      241 acttcatttt ataaaattat caatactata attattatct taggtaagtt attgcataat
      301 acaaaaattc ataataactt atttgcttgc tccattcact ttttaagagt aataaaataa
      361 cctgcaacat agactttaac atccaagttt caggttagcg taatgtaaat tatttacttt
      421 gttatattat gattaaacat ctaattctct gcttgtaagt gctttaatca tctctggatc
      481 agcatgtgag aaaaattggc tattactttc ttctaatgtc gcaatttgtt gtttatcttc
      541 ttctgtaagt tcaaaatcaa atatatctaa gttttgagcc atacgttctg gattcactga
      601 ttttgcgagt acaacaatgt cacgttctac taaccagcgt aaaataactt gtgcaattga
      661 tttgttgtat ttatctgcaa tagcctgcaa caattgattt tggaataatt gatttttacc
      721 ttctgcaaat ggtgcccaag cttctaccac aacattttct tgttgaagtg ctgcaacttg
      781 ttcttcttgt tgatggaatg gattaatttc tatttggttc acttgtggtt gaatttgatt
      841 gtgaatacct aaatctacaa ttcgatcaac gccgaagtta gatacaccga ttgctttaat
      901 tttaccattt tcttttaact cttctaatgc acgccatgag ccatatacgt cattgtaagg
      961 ttggtgaata agcactagat caagatagtc caaatttaat cgttgtaatg atcgttcgat
     1021 tgatttgata gtatcttcat agttaacatt ttcaatccat actttagtcg taatgaatag
     1081 ttcacttcta tcaatacctg aagcttcaat accttgacct acttcagttt catttaaata
     1141 actttgtgct gtatcaatat gtctataacc cgctttaatt gcttctttaa ccgcttctgc
     1201 tgtttgttct tgaggaattt gaaatactcc gaaacctaat actggtatct ttacatcttt
     1261 acttatttca atatgattca taaaatgaac ctcctttatc ttgtatgtcc actataaacc
     1321 atggagcgaa ctctatagca agccagaggt ttactttctc tcccaaagac gttcaacatt
     1381 gtcatcatga ttatcactag cattgatttt agcaatatga ttatcataat tatcaatttt
     1441 atattttagt aaatctctcg catcatgaat tgtctttaag ttttcattta attcttcgag
     1501 ttgcttattt aaaatttgct tttgctgtgt ttgaatattt ttatttttag gaagctgcgc
     1561 taatctacaa aattcgataa gcgattcaat actgacgcct gcatttcgca aatttttcac
     1621 taaataaatc caatttaaat cactatcatt atatattcta tatccatttt catctcgatt
     1681 aacgggtgga atcacaccaa ccttttcata atatcttaaa gtgtcttgag atatattcat
     1741 gagcgctacg acttctttag ttttcattgc gactatcctt tcagttatat ttgggcatct
     1801 aaagtaatgt tgttttatat attgccatct ttgtttgaat acttcttatt ttattactca
     1861 aatttaaatt tgtctctttt ttaacatttt acatttcatc gtttttaatt actttaaaaa
     1921 ttgtataact taaatattta aaatgatata atcactaaga ttgataatat ttaatttttt
     1981 aaaaattatt tttgttgcaa tttttgggtg atacggaaaa tttgggtgat cgatcgttta
     2041 tatgcatcaa cattctttgt ggattgtttg acagtagaca gtcatttgta tacgttaacg
     2101 aattttgaaa atttgaatca ttatttaatc atattattaa ttgcgcacgc acaacataaa
     2161 aaggagacat gtcaatgaca tatagaatga agaaatggca aaaattatcc accattacgt
     2221 tattaatggc tggtgtgatt actttgaatg gtggtgaatt cagaagtatt gataaacatc
     2281 aaatcgctgt ggctgatacg aatgttcaaa cgccagatta tgaaaagttg aggaacacat
     2341 ggttagatgt taactacggt tatgataagt atgatgagaa gaatgacgca atgaagaaga
     2401 agtttgatgc tacggagaaa gaggcagaga aattactcag tagcatgaaa actgaaagtg
     2461 gaaggactta cttgtgggat agtgcaaaag atttagataa caagtctgcg gatatgactc
     2521 gtacctatcg taatattgag aaaatcgcag aagcgatgag gcatcctaaa accactttaa
     2581 atactgacga aaataagaag aaagtgaaag atgcccttga gtggctgcat aaaaatgcat
     2641 atggaaaaga accagataat aaagtaaaag aattgactga gaattttaaa ataactgatt
     2701 catcaaagaa aaaagcttta aattggtggg attatgaaat tggaacacct agatcattaa
     2761 caaatacgct tatattgctg aatgatcaat tttcaaatga agaaaagaaa aaattcactg
     2821 cccctattaa aactttcgcc ccaaaaagtg atgaaatatt atcttctgta ggaaaagctg
     2881 aacctgctaa aggcggaaat ttagtagaca ttgctaaagt aaaactttta gaaagtatta
     2941 tcgaagaaga taaagatatg atgaaaaatt caatagattc atttaataaa gtcttcactt
     3001 acgttcaaga ttctgccact gataaagaac gtaatggatt ttataaagat ggttcatata
     3061 tcgaccataa agatgtccca tacactggtg cttatggcgt tgtactctta gaggggattt
     3121 ctcaaatgat gccgatgata aaagaaacac cttttaatga taaaacccaa aataatacaa
     3181 ccttaaaatc atggattgac gacggatttt taccactcat ttataaaggt gaaatgatgg
     3241 atttatcacg tggtagagcc attagccgtg aaaatgaaac gagtcactca gcatctgcaa
     3301 ctgtaatgaa atcattgttg agattaagtg atgccatgga tgattcaaca aaagctaagt
     3361 ataaaaaaat tgtcaaaact tcagttaaat ctgattcaag ttacggccaa aatgatacat
     3421 taagctctta ttcggatata agcaaaatga agtctttaat ggaagacagc actatttcta
     3481 ctaacggttt aacacaacaa cttaaaatat ataatgacat ggatcgtgtc acctatcaca
     3541 ataaagactt agactttgca tttggtttaa gtatgacgtc gaaaaacgtc gcacgttacg
     3601 aaagtatcaa cggagagaac ttaaaaggtt ggcacactgg tgctggaatg tcttatttat
     3661 acaatagcga tgtgaaacac taccgtgata acttctgggc gacagctgat atgaaacgtt
     3721 tagcaggtac aacaacttta gaaaatgaag aacctaaagg tacggatgtt aaaaagtcga
     3781 gtaaaacttt tgtaggcgga acaaaattcg atgaccaaca tgctagtatc ggaatggatt
     3841 ttgaaaatca ggacaaaact ttaactgcca aaaaatcata tttcatatta aacgataaaa
     3901 ttgtcttctt aggaactggc attaaaagta ctgattcatc aaagaatcca gttacaacga
     3961 ttgaaaatcg caaagcgaat gggtatacgt tatatacaga cgataaacaa acaaccgctt
     4021 ccgataatca gggaaccaat tccgtctttt tagagtcaac caataaacct aaaaacaata
     4081 taggctatca ttttttaaac gaatcgaaaa taactgtaaa aaaagaaagt catactggta
     4141 agtggagtga tataaataaa agtcaaaagc aagacagtaa aactaatcaa tattatgaag
     4201 taactcaaaa gcattctaat acagatagta aatatgcata tgtgttgtat ccaggcttat
     4261 ctaaagatga ctttaataca aaaaaagata aagtaactgt cgttaaacaa gatgatgact
     4321 tccacgttgt gaaagataat gaatcggttt gggctggtgt taattatagt aatagcactc
     4381 aaacttttga cattaacaac actaaagtcg aagttaaagc caaaggaatg tttattctta
     4441 aaaacaaaga tgataacact tatgaatgta gcttctataa tcccgaatct acaaataccg
     4501 cttcagatat tgaatctaaa atttcaataa ctggatactc tattacaaac aaaaatacat
     4561 caacttctaa tgaatccggc gtacactttg aattaactaa ataagcaaga aaatctcgac
     4621 actataccat ttttatagtg tcgagatttt ataagtatcg ccatcattca ccttgtaatc
     4681 cgcagaccac atcccctttg ataagttcta gattatttaa aaatcgaatt ttcaaagacg
     4741 tacatgcttc aatattctta tcattcatta cttggaaatg tatatgaggt tcagtagaat
     4801 tgccagaatt cccaaccttc ccaaggaagt caccatattt aacattttgc ccctcattca
     4861 caatgattga atattgttgt aaatgagcta ttaagctata ctcattttct gcgtgcttaa
     4921 ttacaatata atttcctaaa aactgtgatt cattcgtact tccaatactg ttgtcttgaa
     4981 ccccattcac tactttttca actgtaccat ttgctggcgc aatgatatct tttccaaaac
     5041 aaaaataatc agtatttact tttccttgat tcttatatgt tttatgattt tctttaataa
     5101 ctaaatcaat agcatacctt tgatgtaggt ataaatagtg ataattatat aattcattat
     5161 ctccacccca aaaaacctca tagcaatctg ttgtcggcac tgcgtatttt aaagtcgttt
     5221 cattcttaat cgcatcataa ttgattaacg gacgcataac aaatccgata atactattat
     5281 ctttccaagt cactgccact ccaaattgat ttgctttatc tatccatatt tgctccatag
     5341 tatcatcatt ttgagtacac acttttaact catgtacatc agactgcctt gtataagatt
     5401 tgaaaagttt cctaaactgc caataactaa actctcgctt caaattttga tcaaaaatct
     5461 tatatatttt cctgctctta cttttattta aataatcccc aaagtttgtt ttattcatat
     5521 atacttaacc tcttatatta attttggtat caattctttc tccagttcct gcgtcatttt
     5581 tgcgctacct gaatcgtcta cacttaattg gacaaatcaa catataaata attttttaaa
     5641 actaaagtgt agtctattca ccatattttc taatcatccc ttaaatatta atatttgcac
     5701 ttaaaaagta tacatatcac tcaactaatc aataatcata cttaccttca acaaattctt
     5761 taacatgcag tgttatccct tgataatatg gatattttgt taatctaaat ttctgcttta
     5821 atgcttcatc tctactattc gacatcaaat atgcatgttc aagatagctt aaatatgctt
     5881 cgtcattgcc gctatctcca aaacctaata ttgattttac tggtatattg tattttttca
     5941 tcagaaattg agtagcatat aattttccag catttgacgg tgtgaagtca atatcatacg
     6001 cattttcagg atcaccagct aatggattgc ttcgactaaa tctcgctgta tagttttggt
     6061 catttgcgta tctgacaagt gcttctagga tacgactatc attgttgtga ttacctgttg
     6121 aatgaaaata aaaattataa tgtgtttcat taccttcaaa tgctctttgt ggaataaatt
     6181 cgacattata ttgcgcagaa atatgacgta atatatcttc aatatcttca aataaaaatg
     6241 gttcgctcaa gactttcttt ttatatgttt ctgattcaac atattcgcca ttattccaag
     6301 tgaacatttt agaactcaaa tcagaaaaga tatgtaatgg tttaaacgtc atattaactt
     6361 gatccatttt atccatgaca ctttgaaatg tacttcctgt caatacagca gtgatcactt
     6421 cattattatt agttagtttt tccaacaatt tttccatttc tcttaaatga cttaaatctt
     6481 cttcatttgt attatgttta aaatatgttt catcaaaatc aaacaataat agacgctttg
     6541 acatactcat tcccccataa tattctaatg aatttatcta taacttaaat acactataag
     6601 tctcaattaa aagtataaga tcgactatat gcttttcatg cttattatat acaactaatg
     6661 aatccctata aactaaaaac attgcttacc acttttcaaa atacacgggt catatccctc
     6721 gttaaaaact attactaaaa atcaaaaata taaaaaaatc aaaaagtatg ttttaaactt
     6781 tatgaaacgt gttatataaa tagtgtaata taccacaact ttaaaaggag attgagatat
     6841 gaaactaaaa tcatttgtta ctgccacttt agcattggga ttattatcaa cagtaggtgc
     6901 agctttaccg agtcatgaag catctgcaga tagtaataac ggttataagg aattgacaat
     6961 ggatggaaaa cacactgtgc cttacacgat ctcagtagat ggtattactg cattacatcg
     7021 aacttacttt gtttttccag aaaataaaaa ggtactttat caagaaattg acagtaaagt
     7081 aaaaaatgaa ttagcttcac aacgtggtgt tacaacagaa aaaattaata atgcacaaac
     7141 agcaacgtat acacttactt tgaatgatgg taataaaaaa gtagtgaatc taaagaaaaa
     7201 tgacgacgct aaaaattcaa ttgatccaag tacaatcaaa caaatacaaa ttgtagttaa
     7261 ataataattt gaaaatgaaa atagttacac agggcaaacg ctgaaaaatt gcgtttgtct
     7321 ttttagtatg aaatgaatga tcgaacttat aatttcttat tgattgcttc tactgacaat
     7381 agattagatc ggcctatact aaagtaaatt ctatattaat gtcttccgca atttataatc
     7441 taacataaca gcaaatctca aatatctgga acctaataaa tcccctcact actgctaata
     7501 gtgaagggat ttattttatt acttagacgt aattataaat atatttgttc tattgtagtc
     7561 atggttaatc atatttacaa actatcattt ctaaatcgcg cattatgaag tcaattttca
     7621 taaaccgtca ttatatttct ggattcatta ttcagcttct ctaatttcgt ctgcaatatc
     7681 tttatagtca atatttgctt tagtgaaatc tttatcttga attggaaaat gctgttcaaa
     7741 tgtttctata ttttggattt ctactttaac atcttctact tcaaaatcta agacatgtcc
     7801 accaaagtta cgatcatcat tcgcaaagtg tacatgaaat cctgctgatc cgataccatg
     7861 gaataattct ggtgtaaaga aaccaacgac tgaacctttg acatacgttt cagtttgttc
     7921 aggttgtctt ctagctgaat cgattaaacg tgtataaggt ggttcttgag ccggcatcat
     7981 acgtacatgc atttttttaa ataagcctga aatttttact gctgaaaata aattttcact
     8041 caacatcttt tccttaattt ctgcaaaaac tgcttctgaa gatttatctt tcgtttcata
     8101 gcttgtatct gctacaaatt tagttacagt tgcatatggt gttaactcgt caccttttaa
     8161 ttctacaaat tctttatgtt catttgcatg gtaagctttt ccatctaaaa agattacctc
     8221 accgtttgaa cctgttagtg tagcgatacc taagtcacca tgttgcaata attcatttat
     8281 tgatgcagtt ccttttaata atcctgccat taatgtgcct aatgtaccat gttggtataa
     8341 aacattagtc ataaaatctc ccactcctct ttaacattta tctttatttt agttaaatac
     8401 gtcaggtaac atatttgttg aaagtttgat attatctttg taatttacag gtatatcaat
     8461 taatactgga ccatctgttt catagccctc tttaattgcc gcttctaatt cttcttgatt
     8521 agtaactcgt aaacctttcg cgccaaatga ttctgcatat tttacaaaat ctacaggacc
     8581 gaagtctaca cctgacgaac gtttatattt catttcttct tggaattcaa ccatgttata
     8641 ttttccatca ttccaaataa gctggatgat atttaaattt ttacgtacgg ccgtttctaa
     8701 atcttgtgat gaaaataaaa agccaccatc gccagcaacg gacacaactt gcgtattagg
     8761 gcgcacaagt gcagctgaaa ttgcccacgg taatgctaca ccaagcgttt gcataccatt
     8821 gctaaataat aaatgtcttg gattgtaact tctgaaatta cgtgccatcc aaatatagtg
     8881 acttccaaca tcaactgtta cagtagtatc atcagttaat accttttgca tagattcaat
     8941 aatttccact ggatgtagaa ttccttcttc atgcgtcgct ttaataccag tttcttcatc
     9001 aatatgtgtt cttaattgtt ctaattcgtc taaatgttgt tgatttataa atggctcatc
     9061 cactttttca gaaatcattt caatcgtttt agcaatatta ccaatcaact cttttttcgg
     9121 ttgcatataa ttagtaattt cagcttgaac ttcgtcaata ttgataattt gtgtttctaa
     9181 ttctttattc cagttactag cttcgtattc aattggatca taaccgattg taacaactaa
     9241 atcactttta cgtaataatt catcaccaac ttgattgcgg aataagccca cacgaccgaa
     9301 gaaatgattt tctaattcac gactaattac acctgcacct tggaatgttt ctacaactgg
     9361 taaattcgtg cgctcaacta atttgcgaat ggcatttgtt tcttctgcac ttgaacttct
     9421 cataccagct aataaaacag gaaatgatgc atttttaatc gcttcaatga catcattaat
     9481 atcttgttca ctcggtactc ctaaatttgg tttttggcaa agtgatatag ctttagattc
     9541 aactggtgaa gaaataacgt cttgcggaat actaataaaa cttgcgccat tttttcctga
     9601 agtagcaatt cgaattgcat ttgtcataac ttctgataat gattcaggat cttgtacttc
     9661 ttcactgtat tttgatgaat attttaatag cgcagcatta tcaatacttt gatgcgttaa
     9721 tcgtaataaa tcattacgtt tcacttggcc acctaacgct aatacaggat ccccttcaga
     9781 tgtagctgtt aatagtccag tcgttaaatt acttacacca gggccacttg taacaagtac
     9841 tacacccggt ttacctgtta atcttccaat accttgtgcc atcattgcag cattttgttc
     9901 atgacgagtg acaataagtt caggaccatc atcaattaaa gcattaaata gatagtctat
     9961 ctttgcaccc ggaataccaa aaacatattc taccccatta tttttcaaag tatcaataac
    10021 catatcggct gcagtgtact ttttatcagt catttatatt catttccttc caattgtgat
    10081 gtatagatgt gtattacatg taattacatt gtgatttgta atctaatgat agttacgcaa
    10141 aattaatgat gtttatcaaa attttacatg tacgattaga tttgtaatac ataaaaattg
    10201 ccttcattac attatataac ctttgttaga tgaataaaaa tcgttatttg taatactaag
    10261 tattccaaaa atgcatgagt agattttgtg cgttgtgatt atgagggatg ttggattgat
    10321 tgatgtatag gattgttacg atattttggg atgaggtgtt tagtcaatgg cggtttgaaa
    10381 ttgtcgtttt atggtgggct gaaaatgctg ttttatgtcg ggcttgaatt tgtcgtttta
    10441 tggagatata aaaatgctgt tttatggcgg tttcaaaatg gtgtttcgat taataagcca
    10501 cagcaagact tagatctaac tatgacttat acatttcaca cttatattag cgattatttt
    10561 tatagttata aatgatagat gcagttccta aacaaa
//
LOCUS       DAPDIM010000076        10486 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000076 DAPDIM010000000
VERSION     DAPDIM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10486
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.076"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(300..1178)
                     /locus_tag="RFE25_002369"
     CDS             complement(300..1178)
                     /locus_tag="RFE25_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exonuclease"
                     /protein_id="HDU2817405.1"
                     /translation="MPNKILLVDGMALLFRHFYATSLHKQFMYNSQGVPTNGIQGFVR
                     HIFSAIHEIRPTHVAVCWDMGQSTFRNDMFDGYKQNRSAPPEELIPQFDYVKEISEQF
                     GFVNIGVKNYEADDVIGTLAQQYSTDNDVYIITGDKDLLQCINDNVEVWLIKKGFNIY
                     NRYTLHRFNEEYALEPQQLIDIKAFMGDTADGYAGVKGIGEKTAIKLIQQYQSVENVV
                     ENIDALSAGQRNKINDNLDELYLSKRLAEIHTQVPIDSEALFEKMSFATTLNHILSIC
                     NEHELHVSGKYISSHF"
     gene            complement(1198..4638)
                     /locus_tag="RFE25_002370"
     CDS             complement(1198..4638)
                     /locus_tag="RFE25_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HDU2817406.1"
                     /translation="MINKEQLDLLYKLKKEVEKSRNEALLHTINQVIKKVYLQQYTCS
                     FVGHFSAGKSTLINLLIEQDILPSSPVPTTSNTAIVSVSDNHDIIANLPNQTYAKLSN
                     YDEVREMNRQNVDVESVEINFQSAKFENGFTLQDTPGVDSNVASHQSITEQYMYTSNM
                     IFYTVDYNHVQSELNFKFMKHINDVGIPVVFIINQIDKHQDDELSFSTFKSRVEKSIA
                     DWGIKLERTFYVSKFDHPENELEVLSSYLISLDQHRETIEDYTSRTVEYITEAQLDYI
                     QSEIQEVLEDLGIEEAEFEQAFLNSQQHQAISEEAQLLNNPDELMAFLKNKRKNILEN
                     AYIMPHNMREMLRSYLESMSQDFNVGGFFNKKKKKLQIQQQRLLTATDALQEHVNQQI
                     RQPMREDMSFVTRFINKKEASDKVLNQHYDVKPEMIEDLYQPQTSISNTYVLTFSDEV
                     VKAIKKYVEQQSTPIFKEIIENVQADELPTEESDDLKEYQRYTELNELRQSLTTKNYR
                     HYYIHLDESLDKLIGRQETTYQVATDNTQDNRDNQQLNQNTATTNMSIDIQKALDIIS
                     DVPLFKRTKQDIHETLTRIDNKLIKIGVFGTFSAGKSSLINALLGEHILVSSPNPTTA
                     ATTEISYGDESYITLKSQSQLLDEINAVVEYQDISFSTIEEFINWDLEKLKSHLNKNQ
                     LAFIQAVEKHYKLYVNMLENGEKHAINQQELKKWSAEDEYATFVKTVHIALMHDWLKG
                     KIIVDSLGLHSNNQRHTNETEQILTSSDLILYVSYFNHSFTDNDKAFIEHMKDMNQLN
                     ENQAFKMVINAADLAESQDDLEAVETYVSDALRQVHLQSDIFAVSSRNALQAEDKGID
                     QLKQSIQQFVDVESKSILEQQMIHQLQQMDRSYVEMITEFETNKADISRRQQRLTDYK
                     DKQRLQHQLIDATLQHTDNEVEEQVYHLNARLKLQLLDDVKSVFNSQMTQNSDFNEEK
                     KVSTKVYLDQIHQRLFLEQSLITERIKKYFNKQLTKQIAPIVQQLADLHVIVNPQFNF
                     ESANIEQPLLHIDFNDMLNALPKQLTKRKILNPNGQRDIHESICQSTLGLLQPQMGLL
                     RQQLELYVKQMAVEAESQFESFEANIQTQINDLLAFDLDTTLINQLKDKHQQLKTILY
                     "
     gene            4942..6282
                     /locus_tag="RFE25_002371"
     CDS             4942..6282
                     /locus_tag="RFE25_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDU2817407.1"
                     /translation="MKNTFNPLQRLHFYAAIFIAPLLITLTISGIGYLFFPEVENNIY
                     KNEFFGDSDVKTHQTLNDAVHQVEQQYEGFFVSKVSILDEPYNKRITLSDMAGNQRYV
                     FLDHNNQFVADQNAKHTYSNVMRSIHSSLFTENTIINYLVELTACWTIFMILSGTYLL
                     IKKHLISNKSKALRWQKWHAMIGVIIAIPVFVLVLTGLPWSGFMGSKIAGMMDTNGDL
                     GQGELAINPPKSDLNELPWATRKNKQPASSEKGSSGHHGNAAMPQTKLDYQISIDKVV
                     VQAQKAGIKKPFSIVYPSDKNGTFIVSNTSNSGVTGLDVSPYKEQTLYFDQYSGKKLG
                     TIKYDDYGIIAKWFTWGIPLHEGHLFGILNKIINLFVCITLLVAIGMGFVSWIKRTKN
                     TAVKVPHRVKKPASISLIICLIVLGLLMPLFGLSLILVFIIELILYIKDRRAKQ"
     gene            complement(6488..6820)
                     /locus_tag="RFE25_002372"
     CDS             complement(6488..6820)
                     /locus_tag="RFE25_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4889 domain-containing protein"
                     /protein_id="HDU2817408.1"
                     /translation="MGKKMGLGLSIALVVIGIAVVCLMIFSSQKTTYFGYMNSKTNAE
                     KVVSEKDGLVKHNIKVEPSNDFKPKKGDFVKLVSKDDGKTFYKQEIVKHDDVPHGLMM
                     KIHDMHMN"
     gene            complement(6904..8049)
                     /locus_tag="RFE25_002373"
     CDS             complement(6904..8049)
                     /locus_tag="RFE25_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDU2817409.1"
                     /translation="MFQLLAVCPMGLEAVVAREIQELGYETNVENGRIFFEGDASAIV
                     KANLWLRTADRIKIVVGRFNATTFDELFEQTKALPWESIIDKEGNFPVQGRSVKSTLH
                     SVPDCQAITKKAIVERLRRAYNEKGWLNESGAKYPVEVAILKDNVLLTIDTSGSGLNR
                     RGYRLAQGEAPIKETLAASLIRLANWKGDTPLIDPFCGSGTIAIEACLIAQNIAPGFN
                     REFVSEQWNIMPANIYDDYRDEADKMADYDKEIEVYASDIDPEMVEIAKRNAEEVGLS
                     DIIKFSVKDVNTLTIDTEEPVALIGNPPYGERIGDREEVEEMYRYIGKLMKQHPFLST
                     YILTSNKEFEYLVNRKATKRRKLFNGYIECTYYQYWGKKTERKTIEN"
     gene            complement(8258..8637)
                     /gene="rnpB"
                     /locus_tag="RFE25_002374"
     ncRNA           complement(8258..8637)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RFE25_002374"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(8700..9044)
                     /gene="gpsB"
                     /locus_tag="RFE25_002375"
     CDS             complement(8700..9044)
                     /gene="gpsB"
                     /locus_tag="RFE25_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HDU2817410.1"
                     /translation="MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQK
                     MADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILK
                     RISNLEKAVFGK"
     gene            complement(9058..9621)
                     /locus_tag="RFE25_002376"
     CDS             complement(9058..9621)
                     /locus_tag="RFE25_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HDU2817411.1"
                     /translation="MVKTVYVTGYKSFELNIFKDDAPEVHYLKQFIKHKIEQLLDEGL
                     EWVLIQGQMGIELWTAEVVIELQRTYDSLKFAVITPFQGHTEKWNEHNQSKYANIIKH
                     ADYVDSIFHTSYQGPFQFKQADQFMLEHSDQTLLIYDEEQEASPKFFKQMLVDFMDKT
                     NYTCDIVTFDELTAFINDLQWSEDQSF"
     gene            complement(9614..9964)
                     /locus_tag="RFE25_002377"
     CDS             complement(9614..9964)
                     /locus_tag="RFE25_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YppE family protein"
                     /protein_id="HDU2817412.1"
                     /translation="MNDVVESLIYEVNNMQQNFENVKSQQQDHDFYQTVKPYTEHIDS
                     MLNEIKLHREFIIEVPYMNSRKFELLIANIEQLSVECHFKRTSRKLFIEKLKSVQYDL
                     QNILDGVTKEGTYG"
     gene            complement(10019..10198)
                     /locus_tag="RFE25_002378"
     CDS             complement(10019..10198)
                     /locus_tag="RFE25_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001788819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817413.1"
                     /translation="MLLISRGVFDLNDFIRLKVFSSYNNIHDKILYLYRKFLDLLDLT
                     DNTFEKIVKSNYIEC"
BASE COUNT         3278 a         1779 c         1464 g         3965 t
ORIGIN      
        1 ttatactcca tttgatttat agttgtatta atacattgac tcaaaaacta attaatcaaa
       61 tatgtttttt agattaataa agttgtaact gtactatttt gtagtgtatg gtaatttatt
      121 tggatgaaat ataattcttt aaactctatt gattaatcaa atatgtatct atcaaaattc
      181 gtcttattta ttcactctga catatccaaa tacgcaaaaa gactatttct accttgcatc
      241 gatagaaata gtctttttat acttaattgg tttaattttt cataaaattt tatacttttt
      301 taaaaatggg atgaaatata ttttcctgaa acatgtaatt catgttcgtt acaaattgat
      361 aaaatatgat taagtgttgt tgcaaatgac attttctcaa aaagcgcttc actatcaatt
      421 ggtacttgtg tgtgaatttc agcaagtcgc ttcgataaat atagttcatc taaattgtca
      481 ttaatcttat tacgttgccc agctgataat gcatcaatgt tttcaaccac attttcaacg
      541 ctttgatatt gctgaattaa cttaatagcc gttttctcac caattccttt aacacctgca
      601 tatccatctg ctgtatcacc cataaacgct ttaatatcga ttagttgttg tggttcaagg
      661 gcatattctt cgttaaaacg atgtaatgta tatctattat aaatgttaaa acctttttta
      721 attagccaga cttcaacatt gtcattaata cattgcagta aatctttgtc gcccgtaata
      781 atatagacat cgttatcagt tgaatattgt tgtgctaatg tacctataac atcatccgct
      841 tcatagtttt taacgccaat atttacaaag ccaaattgct ctgaaatttc tttaacataa
      901 tcaaattgtg gtatcaattc ttctggtggt gcagaacgat tttgcttata accatcaaac
      961 atatcatttc taaaagttga ttgtcccata tcccaacata cagctacatg tgtagggcgt
     1021 atttcatgta ttgccgaaaa gatatgacgc acaaatcctt gtattccatt tgtaggtaca
     1081 ccttgtgaat tgtacataaa ttgtttatga agacttgtag catagaaatg tctaaataat
     1141 agcgccatac catctacaag taatatttta ttaggcattt aaaacgttcc ttctttctta
     1201 atataaaata gttttcagtt gttgatgttt atctttcaat tgattgataa gtgttgtatc
     1261 taaatcaaat gctaataaat cgtttatttg cgtttgaata ttagcttcaa aactttcaaa
     1321 ttgcgattca gcttctacag ccatttgctt tacatataat tcaagctgtt gcctcaataa
     1381 tcccatttgt ggttgtaata atcctaacgt actttgacaa attgattcat gtatatctct
     1441 ttgcccattt ggattcaaaa ttttacgttt tgttaattgt ttaggcaatg catttagcat
     1501 atcattgaaa tcgatgtgca ataatggttg ctctatatta gctgattcaa agttaaactg
     1561 aggattaaca atgacatgta aatctgctaa ttgttgaacg attggtgcaa tttgcttagt
     1621 gagttgctta ttaaagtatt tttttatacg ttctgtaatt aaagattgct ctaaaaacaa
     1681 tcgttgatga atttgatcta agtatacttt cgtagacact ttcttttctt cattaaaatc
     1741 actattttgc gtcatttgag aattaaacac tgatttaaca tcgtcaagta gttgtaattt
     1801 taaacgtgca tttaaatgat aaacttgttc ttcaacttcg ttgtctgtat gttgtagcgt
     1861 cgcatcaatt aattgatgtt gtaaacgctg tttatcttta taatctgtta acctttgttg
     1921 gcgacgtgaa atatcagctt tatttgtttc aaattctgta atcatctcta cataagaacg
     1981 atccatttgt tgaagctgat gaatcatttg ttgttctaaa attgatttag attcaacatc
     2041 aacaaattgt tgtatgcttt gttttaattg atcaatgccc ttatcttcag cttgcaatgc
     2101 atttcgactt gatacagcaa aaatgtctga ttgtaagtgt acttgtctta atgcatctga
     2161 tacatatgtt tcaactgctt caagatcatc ttgactttct gctaaatcag cagcattaat
     2221 taccatttta aatgcttggt tttcattcaa ctggttcata tctttcatgt gttctataaa
     2281 cgctttgtca ttatcagtaa atgaatgatt aaaataactt acatacaata ttaagtctga
     2341 agaagttaaa atttgttcgg tttcatttgt atgcctttgg ttatttgagt gtagccctaa
     2401 tgaatcaaca attattttac cttttaacca atcatgcatt aatgcaatgt gtactgtctt
     2461 aacaaatgtt gcatattcat cttctgcact ccactttttc aattcctgtt gattaatggc
     2521 atgtttttct ccattttcca acatattgac atacaattta taatgttttt caactgcctg
     2581 aataaaagcg agttgatttt tatttaaatg tgattttaac ttttctaaat cccaattaat
     2641 aaattcttct atagttgaaa aagatatatc ttggtattca actactgcat taatttcatc
     2701 taataattgc gattgtgatt ttagcgttat ataactctcg tctccataag atatttctgt
     2761 agtagctgct gtagtaggat ttggagaact cactaaaata tgctcgccta ataatgcatt
     2821 tatcaaacta cttttacccg cactaaatgt tccaaataca cctattttta ttaatttatt
     2881 atctatacgt gttaatgttt cgtggatatc ttgctttgta cgcttgaaca aaggcacatc
     2941 cgaaattata tcaagcgctt tttgaatatc tatagacata tttgttgtag ctgtattttg
     3001 atttagctgc tgattatcac gattatcctg agtattatca gtagccactt gatatgttgt
     3061 ctcttgtcga cctattaatt tatctagaga ttcatctaaa tgaatatagt agtgacgata
     3121 attcttagtc gtcaatgact gacgcagctc atttaattct gtataacgtt gatattcttt
     3181 taaatcatca ctttcttctg ttggtaattc atctgcctgc acattttcta ttatttcttt
     3241 aaaaatcggt gttgattgtt gttcaacata tttcttaatg gctttaacca cttcgtctga
     3301 aaatgtaagt acataagtat tgctgattga tgtttgtggt tgatataaat cttcaatcat
     3361 ttccggttta acgtcataat gctgatttaa tactttatct gaagcttctt ttttattgat
     3421 aaaacgcgtt acaaatgaca tatcttctcg cattggttga cgaatttgtt gattaacatg
     3481 ttcttgtaac gcatctgtcg ctgttaataa tcgctgttgt tgaatttgta gctttttctt
     3541 ctttttatta aaaaacccac caacattaaa atcttgagac atactttcca aataacttcg
     3601 taacatttct ctcatattat gcggcataat gtatgcattt tctaaaatat ttttacgctt
     3661 attctttaaa aatgccatta attcatctgg attatttaaa agttgtgcct cttcactaat
     3721 tgcttgatgt tgttgactat ttaaaaatgc ttgttcaaac tccgcttctt cgatacctaa
     3781 atcttctagt acttcctgaa tttcagactg aatgtaatct agctgagctt cggtaatgta
     3841 ttcaaccgtt cttgatgtat aatcctctat tgtctctcta tgttgatcta atgaaattag
     3901 ataacttgat aatacttcaa gttcattttc agggtgatca aatttagata cataaaaggt
     3961 gcgttctaat ttaatgcccc aatctgcaat tgatttttca actcgtgatt taaacgtaga
     4021 gaatgacaat tcatcgtctt gatgcttgtc aatttgatta atgataaaca caacaggtat
     4081 tccaacatca tttatatgct tcataaactt aaagttaagt tcagattgaa cgtggttata
     4141 gtcaaccgta taaaatatca tattacttgt atacatatat tgttctgtta ttgactgatg
     4201 tgatgcaaca tttgaatcaa cacctggtgt atcttgcaac gtaaacccat tttcaaattt
     4261 agctgattga aaattaattt ctacagattc aacgtcgaca ttttggcgat tcatttccct
     4321 tacttcatca taattagata atttggcata tgtttgattc ggcaaattag caataatatc
     4381 gtgattgtct gaaactgaca caatagcagt attacttgtc gttggtacag gtgaacttgg
     4441 taagatatct tgttcaatta ataaatttat cagtgtcgat ttacctgcag aaaaatgtcc
     4501 aacgaacgaa catgtatatt gctgcaaata tactttctta attacttggt taattgtatg
     4561 taaaagtgct tcatttcgcg acttttcaac ttcttttttt aatttatata aaagatctaa
     4621 ttgttcttta ttaatcatgt tactttcccc tttggttcgt tcacatagaa atgcttgctt
     4681 gttaaaacga attcatacaa tatcgatgtc catttaaaca tagatcgtta aatggctcgc
     4741 attgtattat gtttaaattt tatcatagct gcttgataaa acatacgaat aatcaatttt
     4801 cttcaaacat tccaacttaa aagttcatat ttctaaaaat cacaaatcat cgttaaattt
     4861 ttctagaaaa taaatattgt cacagtttgt tcacacacgt cacagaattg acaccgtata
     4921 atagccaatt gggagggaaa tatgaaaaat acatttaatc cattacaaag attacatttc
     4981 tatgcagcaa tatttattgc tccactgtta atcactttaa ccatttcggg cattggttac
     5041 ttgttctttc cagaagttga aaataatatt tataagaatg agttttttgg tgacagtgat
     5101 gtaaaaacgc atcaaacatt aaatgatgca gtacatcaag ttgaacaaca atatgaagga
     5161 ttctttgtaa gtaaagttag catacttgat gaaccatata acaaacgaat tacactgagt
     5221 gatatggcag gaaatcaacg ttacgtcttt ctagatcata acaatcaatt tgttgcagat
     5281 caaaatgcga aacatacgta ttctaatgtg atgcgaagta tacatagttc tttgtttact
     5341 gaaaatacta ttattaatta tttagtagag ttaaccgcat gttggacgat attcatgatt
     5401 ttatctggta cttatttact cattaagaag catttaattt ctaacaaaag taaggcactt
     5461 cgttggcaaa agtggcacgc aatgattgga gttatcattg caattccagt atttgtatta
     5521 gttttaactg gattgccatg gtctggtttt atgggcagta aaattgccgg tatgatggac
     5581 acaaacggtg accttggtca aggtgaatta gcgattaatc cacctaaatc agatttgaac
     5641 gaattacctt gggctacacg taaaaataaa cagccagctt catccgaaaa aggttcaagt
     5701 ggtcatcatg gtaatgcagc aatgcctcaa accaaattag attatcaaat atctattgat
     5761 aaggtcgttg tacaagcgca aaaagctggt attaaaaagc cgttttcaat cgtatatcca
     5821 agtgataaaa atggtacctt tattgtatct aatactagta attcaggtgt tactgggcta
     5881 gatgtatcac cttacaagga acaaacactt tatttcgacc aatatagcgg taaaaagcta
     5941 ggtacgatta aatatgatga ctacggtatt attgctaaat ggtttacatg gggcattccg
     6001 cttcacgaag gtcatttatt cggcatttta aataaaatca ttaatttatt tgtatgtatc
     6061 actttattag tagccattgg catggggttt gtctcttgga taaagcgtac aaaaaatact
     6121 gcagtaaaag taccacatcg cgtaaaaaaa ccagcatcta tatcactcat aatatgttta
     6181 attgtattag gattattaat gccattattt ggattatcac ttatccttgt atttataatt
     6241 gaattaatat tatatattaa agatcgtcgt gctaaacaat aatgcactta aagttttgaa
     6301 ctgacgaaat ttacaaaatg attctcgtct ctctaattac ttaaaacggg ttctataata
     6361 aatcgtactg atggaaagtt tttacttttt atctgtcaga ttttttgaat ttgaagataa
     6421 aaaagcatct aaaacgcata agaagataac tctacttctt caaaattacg ttatagatgc
     6481 ttttttatta attcatatgc atgtcgtgaa ttttcatcat taaaccgtgt gggacgtcat
     6541 catgtttaac aatctcttgt ttataaaatg tcttcccatc atctttagaa actaatttta
     6601 caaagtctcc ttttttcggt ttaaaatcat ttgatggttc tactttgata ttatgtttga
     6661 ctaatccatc tttttcactg acaacttttt ctgcatttgt tttactattc atataaccaa
     6721 aataagtcgt tttttgacta gaaaaaatca ttaaacatac aacggcaata ccaataacaa
     6781 ccaatgctat agataaacct agacccattt ttttacccat ttatagactc ctccattttt
     6841 caaaaatacc tattatcatg agaacttaat tattactaat tttagtcacg cattagaaac
     6901 actttagttt tcaatagttt tacgttctgt ctttttaccc cagtattgat aataagtaca
     6961 ttctatatat ccattaaata acttacgtcg cttcgttgct ttacgattta ctaaatattc
     7021 aaattcttta ttacttgtta aaatgtatgt agataaaaat ggatgttgtt tcattagttt
     7081 accaatataa cggtacattt cttcaacttc ttcacgatca ccaatacgtt caccatatgg
     7141 aggatttcca attaacgcca ccggttcttc tgtatcaatt gttaatgtat tgacatcttt
     7201 tacactaaat ttaataatat cagacaaccc aacttcttca gcgttacgct tagcaatctc
     7261 taccatttct ggatcgatat cagaagcata tacttcgatt tctttatcat aatcagccat
     7321 cttatccgct tcatcacggt aatcatcata aatatttgct ggcatgatgt tccattgctc
     7381 tgatacgaac tcgcgattaa aaccaggtgc gatattttga gcaattaaac aagcttctat
     7441 agctattgta cccgaaccgc aaaatggatc aattaaaggt gtatcacctt tccagtttgc
     7501 aagacggatt aaacttgctg ccaacgtttc tttaattggt gcttcacctt gtgctaatct
     7561 ataaccacgt ctgttcaaac cagaacctga tgtgtcgata gtcaataata cattatcttt
     7621 taaaatagca acttcaacag ggtatttggc acctgattca tttaaccaac ctttttcgtt
     7681 atatgcgcga cgtaatcgtt caacaatagc tttcttagtt atcgcctgac aatctggcac
     7741 actatgtagt gttgatttaa cgcttctacc ttgaactggg aagttacctt ctttatcaat
     7801 tatagattcc caagggagcg ctttggtttg ttcgaataat tcgtcaaacg ttgttgcgtt
     7861 aaaacgtcca acaacaattt tgattcggtc tgctgtgcgc aaccataaat ttgcctttac
     7921 aattgcactt gcgtctcctt caaaaaatat acgaccattt tcaacatttg tttcatagcc
     7981 taattcttga atttccctag caacaacagc ttctaatccc atcggacaaa ctgcaagtaa
     8041 ttgaaacata tatgattctc cttttataca ggtattttat tcttagcttg tgttttttat
     8101 acatttccaa caaatttaat cgctgataca ttaacgcatc cgcttactat tttaaaacaa
     8161 ggcagtgtca ttatatcaag acaaggcgtt aattttaagt gttcttttca tgaaaaaagc
     8221 tctccatcat ctaggagagc taaactagta gtgatatttc tataagccat gttctgttcc
     8281 atcgtactca tcacgtgcac tagtcacact ggtactcagg tgataaccat ctgtctacac
     8341 cacttcattt cgcgaagtgt gtctcgttta tacgttgaat tccgttaaac aagtgctcct
     8401 accaaatttg gattgctcac tcgaggggtt taccgcgttc caccttttat atttctataa
     8461 aagctacgtc actgtggcac tttcaaatta ctctatccat atcgaaagac ttaggatatt
     8521 tcattgccgt caaattaatg ccttgattta ttgtttcatc aagcacgaac actacaatca
     8581 tctcagactg tgtgagcatg gactttcctc tatataatat agcgattacc caaaatatca
     8641 cttttaaaat tataacatag tcattattag taagacagtt aaacttttgt atttagtaat
     8701 tatttaccaa atacagcttt ttctaagttt gaaatacgtt ttaaaatatc tacattattt
     8761 gaagatgtat ttgttgttgt attattcgaa gaaaaacttt tattgtcctg aggtcttgat
     8821 gttgctacac gtagtcttaa ttcttctaat tcttttttaa gtttatgatt ctcttctgat
     8881 aattttacaa cttcattatt catatcggcc attttttgat aatcagcaat aatgtcatct
     8941 aaaaatgcat ctacttcttc tcttctatag ccacgagcca tcgttttttc aaaatctttt
     9001 tcataaatat cttttgctga taatttcaat gaaacatctg acattttttc cacctcatta
     9061 gaaactttga tcttcagacc actgtaagtc attgatgaat gctgttaatt catcgaacgt
     9121 cacaatatca caagtatagt ttgttttatc cataaaatca actaacatct gcttgaagaa
     9181 cttaggactt gcctcttgtt cctcatcata aatgagcaat gtttgatccg aatgttcaag
     9241 cataaattga tctgcttgtt taaattgaaa aggaccttga tacgacgtat gaaaaatact
     9301 atcaacataa tctgcatgct taattatgtt ggcatactta ctttgattat gttcattcca
     9361 cttttctgta tgtccttgga acggtgtaat tacagcaaac tttaacgaat catatgttcg
     9421 ttgtaattca ataacaactt ctgcagtcca taattctata cccatttgcc cttgtattaa
     9481 cacccattct aatccttcat ccaacagttg ttcaatttta tgttttataa attgttttaa
     9541 ataatgtact tcaggtgcgt catctttaaa aatgtttaat tcgaatgatt tgtaacctgt
     9601 tacataaact gttttaacca taagtaccct cttttgttac gccatctaat atattttgta
     9661 aatcatattg gacactttta agcttttcta taaataactt tcgacttgtt cgcttaaaat
     9721 gacattcgac agaaagttgt tcaatgttag caatcagtag ctcaaatttc cttgaattca
     9781 tataaggtac ttctataata aattcacgat gtaatttgat ctcattgagc atgctatcaa
     9841 tatgttcagt atatggcttt acagtttggt aaaaatcatg atcttgttgt tgtgatttca
     9901 cattttcaaa attttgttgc atgttgttaa cttcataaat tagtgattcg actacatcat
     9961 tcatgaggac gcctcctaca ttttttaatt tatcacaata tactgtattc gtcatgtttt
    10021 aacactctat ataatttgat ttaactattt tttcaaatgt gttatctgtt aaatcaagta
    10081 aatctaaaaa cttcctatat aaatacaaaa ttttatcgtg tatgttgtta tacgatgaaa
    10141 atacttttaa tctaataaaa tcatttaaat caaatacacc tctgctgatt aacaacacat
    10201 acttgtactt gcctcaaaaa taaaaattac tgatcatgat ttgactttta taacaaaatt
    10261 caaaaatatt gtaatgagta ttcattttta taagcaaaac ttttcaatta attaaaattg
    10321 tgtgtaaaat tccaacatta acggtaaatg tattataata ttattgtgtt aatgctgaaa
    10381 tcacgttaaa ataagctttg gtgtattgtg tctttcgcat ttatactaat ttaagtttgg
    10441 tgtttcacta taatgttgtg tataataaac aacgtttact accaaa
//
LOCUS       DAPDIM010000077        10451 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000077 DAPDIM010000000
VERSION     DAPDIM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10451
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.077"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            683..1978
                     /gene="purB"
                     /locus_tag="RFE25_002379"
     CDS             683..1978
                     /gene="purB"
                     /locus_tag="RFE25_002379"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDU2817414.1"
                     /translation="MIERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKAD
                     VQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTAL
                     SFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTE
                     MQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDR
                     HAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSEN
                     ITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRL
                     TVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFREL
                     IEQDESITSVLTKEELDECFDPKHHLNQVDTIFERAGLA"
     gene            2087..2389
                     /locus_tag="RFE25_002380"
     CDS             2087..2389
                     /locus_tag="RFE25_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817415.1"
                     /translation="MQIEKLRGAALDELFDAILTLENREECYQFFDDLCTVNEIQSLS
                     QRLQVAKMIKQGYTYATIEQESGASTATISRVKRSLQWGNDAYTMILDRMNIETNE"
     gene            2561..3253
                     /locus_tag="RFE25_002381"
     CDS             2561..3253
                     /locus_tag="RFE25_002381"
                     /EC_number="2.5.1.n9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heptaprenylglyceryl phosphate synthase"
                     /protein_id="HDU2817416.1"
                     /translation="MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVT
                     EDNVIHLMSRIRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALK
                     TYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYI
                     EYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKK
                     ALKTVKIKESSK"
     gene            3250..5442
                     /gene="pcrA"
                     /locus_tag="RFE25_002382"
     CDS             3250..5442
                     /gene="pcrA"
                     /locus_tag="RFE25_002382"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HDU2817417.1"
                     /translation="MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     LDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADR
                     IGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKE
                     ATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHV
                     DEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTI
                     FLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIR
                     EIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLS
                     YLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSK
                     KVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENID
                     EFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIV
                     FIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQS
                     NMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGD
                     KVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED"
     gene            5446..7449
                     /gene="ligA"
                     /locus_tag="RFE25_002383"
     CDS             5446..7449
                     /gene="ligA"
                     /locus_tag="RFE25_002383"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDU2817418.1"
                     /translation="MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIK
                     IEEEHPEYKTVDSPTVRVGGEAQASFKKVNHDTPMLSLGNAFNEDDLRKFDQRIREQI
                     GNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPL
                     NVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFI
                     YSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYD
                     IDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTA
                     ILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDA
                     VTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKI
                     IQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLG
                     IRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQ
                     KLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSS
                     VTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS"
     gene            7462..8661
                     /locus_tag="RFE25_002384"
     CDS             7462..8661
                     /locus_tag="RFE25_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CamS family sex pheromone protein"
                     /protein_id="HDU2817419.1"
                     /translation="MKRTLVLLITAIFILAACGNHKDDQAGKDNQKHNNSSNQVKEIA
                     TDKNVQGDNYRTLLPFKESQARGLLQDNMANSYNGGDFEDGLLNLSKEVFPTDKYLYQ
                     DGQFLDKKTINAYLNPKYTKREIDKMSEKDKKDKKANENLGLNPSHEGETNPEKIAEK
                     SPAYLSNILEQDFYGGGDTKGKNIKGMTIGLAMNSVYYYKKEKDGPTFSKKLDDSEVK
                     KQGKQMASEILSRLRENDDLKDIPIHFAIYKQSSEDSITPGEFITQATAEKSQTKLNE
                     WHNINEKSALLPSSTAADYDENLNNNFKQFNDNLQSYFSNFTQAVGKVKFVDKKPQRL
                     VVDLPIDYYGQAETIGITQYVTEQANKYFDKIDNYEIRIKDGNQPRALISKTKDDKEP
                     QVHIYSN"
     gene            complement(8750..10288)
                     /gene="putP"
                     /locus_tag="RFE25_002385"
     CDS             complement(8750..10288)
                     /gene="putP"
                     /locus_tag="RFE25_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HDU2817420.1"
                     /translation="MLTMGTALSQQVDANWQTYIMIAVYFLILIVIGFYGYKQATGNL
                     SEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINY
                     FVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVVFFTLYTHSGFVSG
                     GKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAM
                     MNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHK
                     MLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVG
                     GFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEKAKTHQKEFVMIGRLSVLVV
                     AIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALV
                     VIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDI
                     VREK"
BASE COUNT         3953 a         1520 c         1917 g         3061 t
ORIGIN      
        1 gaaagtttca tgaaaatata ttagtcgatt ttgaaagaag cgtagtcaat ttatgtcttt
       61 ctataaaaat ttactattaa aaaaatctct gcgtattttt ctataatcag tttcgtattt
      121 atacgattct ggagttcaat attaatgtct tatatttaaa atgccacacc tatgcaatag
      181 aatatatatt ctttttgtga gtagaaaatt tgttatatta gaagcgaata attttaaaac
      241 atattatgaa atgtaagaag aaatattatg aaactaggaa aagtagattg ttgaaaattc
      301 catacaatag gagaagtaaa gtgaataaat tctggtatta ctaaagctat tgattgtcct
      361 aattgttata aaaagttgga tagtgtagtt gaggggagaa aaactaaaat gcaaaaatat
      421 attcttaatg gatcattata aataccaatt agattaaagt attgcgaaca tttacaatta
      481 gaaatcagta ttaatctgcc atagataatt gtattaatgt aaaaaataaa atagaatgag
      541 aatatacgga aattttttat acatttataa ccaattctgt taaactgtga agagtagagt
      601 taaaaacgaa ctttttgttt atttttatta aaaatgttct gtttttgaaa attcgagtat
      661 acatacgata ggagttaaaa aaatgattga acgctattct agagaagaaa tgtctaatat
      721 ttggactgat caaaatcgct atgaagcatg gttagaagtg gaaattttag catgtgaagc
      781 atggagtgaa ttaggacata taccgaaagc tgacgtacaa aaaattcgtc aaaacgcaaa
      841 ggtaaatgtc gaacgtgcac aagaaattga acaagaaacg cgccatgatg ttgtagcctt
      901 tactagacaa gtttctgaaa cgctaggtga agaacgtaag tgggtacatt atggtttaac
      961 ttctactgat gttgtagata cagctttaag tttcgttatt aaacaagcaa atgacattat
     1021 tgaaaaagat ttagaaagat ttatcgacgt tttagctgaa aaagcaaaaa attataaata
     1081 tacattgatg atgggacgta cacatggagt gcatgcagaa ccaactacat ttggtgtcaa
     1141 aatggcattg tggtacacgg aaatgcaacg taacttacaa cgtttcaaac aagtaagaga
     1201 agaaattgaa gtagggaaaa tgagtggtgc agtaggtact tttgctaaca ttcctcctga
     1261 aatagaaagt tatgtgtgta aacatttagg tattggcaca gcgcctgtat caacgcaaac
     1321 attgcaacgc gatcgacatg catactatat tgcgacatta gcattaatcg cgacgtcact
     1381 agaaaaattt gccgttgaaa ttcgtaacct tcaaaaaacc gaaacaagag aagttgaaga
     1441 agcatttgca aaaggccaaa aaggttcatc tgcaatgcct cataaacgaa atccaattgg
     1501 ttctgaaaat atcacaggta tttcaagagt cattcgtggt tatattacta cagcttatga
     1561 gaatgtgcca ttatggcatg aaagagatat ttctcattct tctgctgagc gtattatgtt
     1621 accagatgtt acaatagcac tagattatgc attgaatcgt ttcacaaata ttgtggaccg
     1681 tttaactgta tttgaagata atatgcgtaa taacatagat aaaacatttg gtctgatttt
     1741 ctcacaacgt gtcttattag cattaattaa taaaggtatg gttcgtgaag aagcatacga
     1801 caaagtacaa ccaaaagcga tgatatcttg ggaaacgaaa acacctttcc gtgaattaat
     1861 cgaacaagat gagtctatta caagtgtttt aacaaaagaa gaattagatg aatgtttcga
     1921 tcctaaacat catttgaatc aagttgacac tattttcgaa cgcgctggat tagcataaaa
     1981 ttaaataaag taacgattca gatttaataa aatataaatc gctacacttt aatagattaa
     2041 tgcgttaaaa tgacataaag aataaaatta taggggttgt ttcgatatgc aaattgaaaa
     2101 attacgaggt gcagcgttag atgaattgtt tgatgcaata ctaacgttag aaaatagaga
     2161 agaatgttac caatttttcg atgatttgtg tactgtaaat gaaattcaat cactgtctca
     2221 aagattacaa gttgctaaaa tgattaagca aggttatacc tatgcaacga ttgaacaaga
     2281 atctggagca tcgactgcaa cgatttctag agtgaaacgt tcattacaat ggggtaatga
     2341 tgcttataca atgattttag atcgtatgaa tattgaaaca aatgaataat aaatgaacga
     2401 taaacaatgg ttatctatct gcactaataa ggtagataat cattgttttt tcacgaaaaa
     2461 atttacagag taaaagaact taaaattcat attaagtctt tagaactcga cacttaaaaa
     2521 tgctataatc atatgtatgt taaaaaagga gtttcggaaa atgtatgaca ttaaaaaatg
     2581 gcgccatatt tttaaattag acccagctaa acatatttca gatgatgatt tagatgcgat
     2641 ttgtatgtct caaacagatg caattatgat tggtggaact gatgacgtta ctgaagataa
     2701 tgtcattcat ttaatgagca gaataagaag atacccattg cctttagtac ttgaaatatc
     2761 aaatatcgaa agtgtaatgc ctggttttga tttttatttt gtacctacag tactgaacag
     2821 tacagatgtt gcatttcaca atggtacatt attagaagcg cttaaaacat atggacatag
     2881 tatagatttt gaagaagtaa tatttgaagg gtatgtcgtg tgcaatgctg atagcaaagt
     2941 ggcaaaacat accaaagcaa atacagattt aacaacagaa gatttagaag catatgccca
     3001 aatggtcaat catatgtatc gattaccggt tatgtatata gagtatagtg gcatttatgg
     3061 cgacgtatca aaggttcaag ctgtctcaga acatctaaca gaaacgcaac ttttttatgg
     3121 tggcggtatt tcctcagaac aacaagcgac agagatggca gctattgcag atacaattat
     3181 cgtcggtgat attatttata aagatattaa aaaagcttta aaaacagtaa aaataaagga
     3241 gtctagtaaa tgaatgcgtt attaaatcat atgaatacag agcaaagtga agctgtaaag
     3301 acaacagaag gaccattgtt aattatggca ggtgctggtt cagggaagac acgtgtttta
     3361 acacatagaa ttgcttattt attagacgaa aaagatgtct caccatacaa tgttttggct
     3421 attactttta caaataaagc tgcaagagaa atgaaagaac gtgttcaaaa attagtaggt
     3481 gatcaagcag aagttatttg gatgtcaaca ttccactcaa tgtgtgttcg tattttacgt
     3541 cgtgatgcag atcgaatagg tatagaacgc aattttacga taattgatcc tacagaccaa
     3601 aaatctgtta ttaaagacgt cttaaaaaat gaaaatattg atagtaaaaa gtttgaacct
     3661 cgtatgttta tcggtgcgat cagtaatttg aaaaatgaac ttaaaacacc tgcagatgct
     3721 caaaaagaag ccacagatta tcactcgcaa atggtagcaa cggtttatag tggatatcaa
     3781 cgccaattgt cgcgtaatga agcgttagat tttgatgacc ttattatgac aacgattaac
     3841 ttatttgagc gtgtaccaga agttctagaa tattatcaga acaaattcca atatattcat
     3901 gtagatgagt atcaagatac taataaagca caatatacat tagttaaatt attagcaagt
     3961 aagtttaaaa acttatgtgt tgtaggtgac tcagatcagt caatttatgg ttggcgtggt
     4021 gctgatattc aaaatatctt atcatttgaa aaagactacc cagaagcgaa tacaatcttt
     4081 ttagagcaaa attatcgttc gacgaaaacg attttaaatg cggctaacga agtgattaaa
     4141 aataattctg aacgtaagcc aaaaggactg tggactgcaa atacgaatgg tgagaaaatt
     4201 cattactatg aagcaatgac agaacgtgat gaagcggaat ttgtaatacg agaaattatg
     4261 aagcatcaac gtaatggtaa gaaatatcaa gatatggcaa ttttatatag aacaaatgca
     4321 caatcacgtg tacttgagga aacattcatg aaatctaata tgccatacac aatggttggt
     4381 ggccaaaagt tctatgaccg taaagaaatc aaagatttat taagttattt gcgtataatt
     4441 gccaatagta atgatgacat tagtttgcaa cgtattatta atgttccaaa aagaggtgta
     4501 ggtccttcat ctgttgaaaa agttcaaaac tatgcacttc aaaacaatat cagtatgttt
     4561 gatgcacttg gagaagctga ttttatcgga ttgtcaaaaa aggtgacaca agagtgtctt
     4621 aatttttacg agttaatcca aagcttgata aaagaacaag aatttttaga aattcatgaa
     4681 atagttgatg aagtattaca aaagtctggc taccgagaaa tgcttgaacg tgaaaataca
     4741 ctagaatctc gaagtagatt agaaaacatc gatgaattta tgtcagtacc aaaagactat
     4801 gaggaaaata ccccattaga agaacagtca ttaattaact ttttaacgga tttatcgtta
     4861 gtagctgata ttgatgaggc agatactgaa aatggcgtaa cactaatgac gatgcactcg
     4921 gctaagggcc ttgaatttcc aatcgtcttt ataatgggga tggaagaatc tttattccca
     4981 catattagag cgattaagag tgaagatgat cacgaaatgc aagaagaacg tcgtatttgt
     5041 tatgtagcaa ttacaagggc tgaagaggtg ttatatatca ctcatgcgac atcaagaatg
     5101 ttatttggtc gccctcagtc gaatatgcca tctagatttt taaaggaaat tccagaatca
     5161 ctattagaaa atcattcaag tggcaaacga caaacgatac aacctaaggc aaaacctttt
     5221 gctaaacgcg gatttagtca acgaacaacg tcaacgaaaa aacaagtatc gtcatctgat
     5281 tggaatgtag gtgacaaagt gatgcataaa gcctggggag aaggcatggt gagtaatgta
     5341 aacgagaaaa atggctcaat cgaactagat attatcttta aatcacaagg gccaaaacgt
     5401 ttgttagcgc aatttgcacc aattgaaaaa aaggaggatt aagggatggc tgatttatcg
     5461 tctcgtgtga acgagttaca tgatttatta aatcaataca gttatgaata ctatgtagag
     5521 gataatccat ctgtaccaga tagtgaatat gacaaattac ttcatgaact gattaaaata
     5581 gaagaggagc atcctgagta taagactgta gattctccaa cagttagagt tggcggtgaa
     5641 gcccaagcct ctttcaaaaa agtcaaccat gacacgccaa tgttaagttt agggaatgca
     5701 tttaatgagg atgatttgag aaaattcgac caacgcatac gtgaacaaat tggcaacgtt
     5761 gaatatatgt gcgaattaaa aattgatggc ttagcagtat cattgaaata tgttgatgga
     5821 tacttcgttc aaggtttaac acgtggtgat ggaacaacag gtgaagatat taccgaaaat
     5881 ttaaaaacaa ttcatgcgat acctttgaaa atgaaagaac cattaaatgt agaagttcgt
     5941 ggtgaagcat atatgccgag acgttcattt ttacgattaa atgaagaaaa agaaaaaaat
     6001 gatgagcagt tatttgcaaa tccaagaaac gctgctgcgg gatcattaag acagttagat
     6061 tctaaattaa cggcaaaacg aaagctaagc gtatttatat atagtgtcaa tgatttcact
     6121 gatttcaatg cgcgttcgca aagtgaagca ttagatgagt tagataaatt aggttttaca
     6181 acgaataaaa atagagcgcg tgtaaataat atcgatggtg ttttagagta tattgaaaaa
     6241 tggacaagcc aaagagagtc attaccttat gatattgatg ggattgttat taaggttaat
     6301 gatttagatc aacaggatga gatgggattc acacaaaaat ctcctagatg ggccattgct
     6361 tataaatttc cagctgagga agtagtaact aaattattag atattgaatt aagtattgga
     6421 cgaacaggtg tagtcacacc tactgctatt ttagaaccag taaaagtagc tggtacaact
     6481 gtatcaagag catctttgca caatgaggat ttaattcatg acagagatat tcgaattggt
     6541 gatagtgttg tagtgaaaaa agcaggtgac atcatacctg aagttgtacg tagtattcca
     6601 gaacgtagac ctgaggatgc tgtcacatat catatgccaa cccattgtcc aagttgtgga
     6661 catgaattag tacgtattga aggcgaagta gcacttcgtt gcattaatcc aaaatgccaa
     6721 gcacaacttg ttgaaggatt aattcacttt gtatcaagac aagccatgaa tattgatggt
     6781 ttaggcacta aaattattca acagctttat caaagcgaat taattaaaga tgttgctgat
     6841 attttctatt taacagaaga agatttatta cctttagata gaatggggca gaaaaaagtt
     6901 gataatttat tagctgccat tcaacaagct aaggacaact ctttagaaaa tttattattt
     6961 ggtctaggta ttaggcattt aggtgttaaa gcgagccaag tgttagcaga aaaatatgaa
     7021 acgatagatc gattactaac ggtaactgaa gcggaattag tagaaattca tgatataggt
     7081 gataaagtag cacaatctgt agttacttat ttagaaaatg aagatattcg tgctttaatt
     7141 caaaaattaa aagataaaca tgttaatatg atttataaag gtatcaaaac atcagatatt
     7201 gaaggacatc ctgaatttag tggtaaaacg atagtactga ctggtaagct acatcaaatg
     7261 acacgcaatg aagcatctaa atggcttgca tcacaaggtg ctaaagttac aagtagcgtt
     7321 actaaaaata cagatgtcgt tattgctggt gaagatgcag gttcaaaatt aacaaaagca
     7381 caaagtttag gtattgaaat ttggacagag caacaatttg tagataagca aaatgaatta
     7441 aatagttaga ggggtatgtc gatgaagcgt acattagtat tattgattac agctatcttt
     7501 atactcgctg cttgtggtaa ccataaggat gaccaggctg gaaaagataa tcaaaaacat
     7561 aacaatagtt caaatcaagt aaaagaaatt gctacggata aaaatgtaca aggtgataac
     7621 tatcgtacat tgttaccatt taaagaaagc caggcaagag gacttttaca agataacatg
     7681 gcaaatagtt ataatggcgg cgactttgaa gatggtttat tgaacttaag taaagaagta
     7741 tttccaacag ataaatattt gtatcaagat ggtcaatttt tggacaagaa aacaattaat
     7801 gcctatttaa atcctaagta tacaaaacgt gaaatcgata agatgtctga aaaagataaa
     7861 aaagacaaga aagcgaatga aaatttagga cttaatccat cacacgaagg tgaaacaaat
     7921 cctgaaaaga ttgcagaaaa atcaccagcc tatttatcta acattttaga gcaagatttt
     7981 tatggtggtg gagatacaaa aggtaagaat attaaaggta tgacgattgg tttagctatg
     8041 aatagtgttt attactataa aaaagaaaaa gatggaccga cttttagtaa aaaactagat
     8101 gatagcgaag ttaaaaagca aggtaaacaa atggctagtg agatattatc aaggttacgt
     8161 gaaaatgatg atttaaaaga tataccaatt cattttgcaa tttataagca atcaagtgaa
     8221 gattcaatca caccaggtga atttatcact caagcgactg cagaaaagag tcaaacaaag
     8281 cttaatgaat ggcataatat caatgaaaaa tcagctttat taccttcttc aacagcagca
     8341 gattatgatg aaaatttaaa taataatttc aagcaattta atgataattt gcaatcatat
     8401 ttttctaatt tcacacaagc agtagggaaa gttaaatttg ttgataaaaa gccacaacga
     8461 ttagtagtag atttaccaat cgattactat ggacaagctg aaacaattgg tattacacag
     8521 tacgttactg aacaagcgaa taaatatttc gataaaatcg ataactatga aattcgtatt
     8581 aaagatggta accaaccacg tgctttaatt agtaagacaa aagatgacaa agaaccgcaa
     8641 gttcatattt acagcaatta attgtaaatt aaagataata aaaaggtacc aatgttagtc
     8701 ataattttga ttaacattag taccttttta atttgttaag acttatgaat tatttttctc
     8761 taacgatgtc acgaactttg tttaagtcag tttcaacaaa tgcaccaggt tttttagtaa
     8821 gtttacttac aacatatgta acgattacac ttacaataaa tccaggaata atttcatata
     8881 agccgaatat ttcgttgata tgtgccaatg gtttaatcca cgcaatccaa acgataacga
     8941 ctaaggcacc tgaaaccatt ccacttacag caccggcacg tgtcaaacct ttccagtaaa
     9001 gtgcaaatag cacaagtgga ctgaacgatg caccaaatcc ggcccaagcg ttacctacta
     9061 agtttagaat tgtgtcgttt ggattccatg caatcgcgat ggcaacaatt gctacaacta
     9121 atacagataa tcttccaatc ataacaaatt ctttttggtg cgttttagct ttttcttcac
     9181 cacgaattaa tttataaaag tcttccgtta gtgaactaga tgttacaagt aattgtgaag
     9241 aaatcgtgct cataattgca gctagaatcg cagcaagtaa gaaaccacct acaagaggat
     9301 ggaagagtac ttgactcatc acgatgaata atgtctcagg atcttctagt ttaatatgat
     9361 aagcaggtac gaatgcaata cctgttaaac caacagccac agcgcctaat aaaccaacag
     9421 ccatccagct aatacctaaa cgtctagctt taggtagcat cttgtgtgat ttaatagaca
     9481 taaaccttac aatgatatga ggttgaccga aataacctaa tccccatgaa aatagagaga
     9541 taattcctat aaatgataac cctttaaata aatttaaatt tgtaggtttc atagctgcta
     9601 catcatgaaa cgttccccag ccgtttaaat tcatcatagc aacaataggg accataacca
     9661 tcgcaattaa cataatgaca ccttggaaga aatctgtaat tgatacagct aaatatccac
     9721 caaagaaagt atagaaaatg acaatgaaag caactaatat taaaccgaaa tgataatcta
     9781 atccaaaagc actttcaaat aatttaccac cagatacgaa accagaatgt gtatataatg
     9841 taaagaatac tacgataatc aatccagaaa taatctttaa cacattattt ttatcgttta
     9901 aacgattttt aaagaaatct ggtaatgtaa ttgcatctcc agctaattcg gtataaacac
     9961 gaagtctagg agcaacaaca aagtaattta tataagcacc taatgttaaa ccgattgtaa
    10021 tccacatagc tgatagacca gtgctataga cagaaccagg tagccccata atcatccatc
    10081 cactcatatc tgaagctcca gctgataatg cagtaatata cggtccaata ctacgtccac
    10141 ctaacatgta ctcgcttagg ttaccagttg cttgcttgta accgtaaaag ccaataacga
    10201 ttagtatcaa gaagtagacg gcaatcataa tataagtttg ccaattggca tctacttgtt
    10261 gacttaatgc tgtccccatt gtaagcatga taaacactcc ctttatttaa tttataattt
    10321 agttacttga aaacattata cataaagata aatgtttaga aaagtaggaa aattaaattt
    10381 attctttttg aaatacttgc ataccaatat aggaagcgct ttcgtatttt ttggatatga
    10441 gcaaattttt a
//
LOCUS       DAPDIM010000078        10431 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000078 DAPDIM010000000
VERSION     DAPDIM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10431
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.078"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..527
                     /locus_tag="RFE25_002386"
     CDS             <1..527
                     /locus_tag="RFE25_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HDU2817421.1"
                     /translation="KYFKDSVLFKQVNYYIDTPDFKLKEHRSALRIRVKDNQYEMTLK
                     TPAKVGLLEYNYIVDIKPEMNLIISNDNLPDDIRQIIVEQFGVKDTTLSILGALTTYR
                     QETKYKGDLLVLDKSEYFDTADYELEFEVKDYNQGLQKFQSLLNELNLEHHQPLNKVQ
                     RFFKKKETLSNNIN"
     gene            631..996
                     /locus_tag="RFE25_002387"
     CDS             631..996
                     /locus_tag="RFE25_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="truncated hemoglobin"
                     /protein_id="HDU2817422.1"
                     /translation="MTTTPYDIIGKEALYDMIDYFYTLVEKDERLNHLFPGDFAETSR
                     KQKQFLTQFLGGPNIYTEEHGHPMLRKRHMDFTITEFERDAWLENMQTAINRAAFPQG
                     VGDYLFERLRLTANHMVNS"
     gene            1019..1825
                     /gene="yjbH"
                     /locus_tag="RFE25_002388"
     CDS             1019..1825
                     /gene="yjbH"
                     /locus_tag="RFE25_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease adaptor protein YjbH"
                     /protein_id="HDU2817423.1"
                     /translation="MAGELRIMENKSREDINLSPVSKIEIYSFFDPFSSDCFKLSAIL
                     SKLRIEYNQYIRIRHILNPSLKVLTKCQAQSTSNFDNIALAYKAAELQGRVRAERFIH
                     LMQNEIIPKRDIITESMICDCIQNAGIDLEVFKDALQKSKLTESLKIDLHIAREMEIE
                     QAPSLVFFSEDVHEEGLKVEGLYPYHIYTYIINELMGKPIEKNLPPKLETYIQQQQLV
                     TMEELLTIYEWPEKLLNKELKKLAIQQKIEKLKYPDGDFWKSKMPKIKSK"
     gene            complement(2285..4093)
                     /gene="pepF"
                     /locus_tag="RFE25_002389"
     CDS             complement(2285..4093)
                     /gene="pepF"
                     /locus_tag="RFE25_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDU2817424.1"
                     /translation="MSQQLSREEQERKYPEYTWDLTTIFKDDEAFEAAFKEVENELGK
                     EEQFKGHIGDSAETLYNALELEDTLGTKLEKVYVYAHLKQDQDTTNDKYTGMESRAHQ
                     LIIKFSSAWSFLVPEILQIDEDKIQSFVNSYDKLQKFAFDLKLINEKRPHILDAETEK
                     LLTEAQDALSTPSNVYGMFSNADLVFEDAIDKDGNAHPLTQGTFIKYLESDDRKLRES
                     AFRNVYKAYGAHNNTLGATLAGEVKKNVFNARTHNYKTAREKALSNNHIPENVYDNLV
                     KTVHKYLPLLHRYTELRKELLGLDDLKMYDLYTPLIKDIKFEMPYEEAKEWMLKALEP
                     MGEEYLNVVKEGLNNRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSNTISDLYTLVH
                     EFGHSAHSYFSRKFQPSNSSDYTIFVAEVASTCNEALLSDYMDKHLDDEKRLLLLNQE
                     LERFRATLFRQTMFAEFEHKIHAIEEAGEPLTPTRMNEEYAKLNKLYFGDSVETDEDI
                     SKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVDRYINEFLKKGSSNYPI
                     EILKNAGVDMTTPEPIEQACEVFEQKLNAFEKLMKA"
     gene            complement(4141..5127)
                     /locus_tag="RFE25_002390"
     CDS             complement(4141..5127)
                     /locus_tag="RFE25_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HDU2817425.1"
                     /translation="MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHF
                     AHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKVEIEPFLKEIKQIPDILINNKYV
                     IELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
                     HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQY
                     IKYCRWQNSVLEPTLSAMYQLQLTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLK
                     NGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDRGNDVQILF"
     gene            complement(5248..5967)
                     /gene="mecA"
                     /locus_tag="RFE25_002391"
     CDS             complement(5248..5967)
                     /gene="mecA"
                     /locus_tag="RFE25_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HDU2817426.1"
                     /translation="MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSM
                     MDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKNEDMMNMSDDDATDQFDEQVQEL
                     LAQTLEGEDQLEELFEQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHS
                     NPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYA
                     KIIMSHNVTAQVRRYFPETTE"
     gene            complement(6338..6733)
                     /gene="spxA"
                     /locus_tag="RFE25_002392"
     CDS             complement(6338..6733)
                     /gene="spxA"
                     /locus_tag="RFE25_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDU2817427.1"
                     /translation="MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQ
                     ILKMTEDGTDEIISTRSKTYQKLNVDIGSLPLQDLYSIIQDNPGLLRRPIILDNKRLQ
                     VGYNEDEIRRFLPRKVRTFQLQEAQRMVD"
     gene            7027..8016
                     /gene="trpS"
                     /locus_tag="RFE25_002393"
     CDS             7027..8016
                     /gene="trpS"
                     /locus_tag="RFE25_002393"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDU2817428.1"
                     /translation="METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHA
                     ITMPQDRLKLRKQTRQLAAIYLASGIDPDKATLFIQSEVPAHVQAGWMLTTIASVGEL
                     ERMTQYKDKAQKAVEGIPAGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVD
                     RFNSRYNDVLVKPEIRMPKVGGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKI
                     KSAVTDSDGIIKFDRDNKPGITNLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEI
                     VKAFLVEFQEKYESFYNSDKLDDILDQGRDKAHKVSFKTVKKMEKAMGLGRKR"
     gene            complement(8058..8939)
                     /locus_tag="RFE25_002394"
     CDS             complement(8058..8939)
                     /locus_tag="RFE25_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817429.1"
                     /translation="MQNKSKSPFKIALSRFIHNKIAMLSIIFLLIITIVSIIAPLIAP
                     FPVNQQDLLNIKGEMTAQNILGTDSGGRDNFSRLLYAGRISLSIGITSTIGMLLIGIT
                     VGVISGYFGGIVDTLLMRITEFVMLFPFLIFAIVLNAALGDKIKNPYGSAIILVLVII
                     VLSWGGIARLVRGKVLQEKENEYFLAAKSIGTPTYKIILKHLLPNILSVVIVQATLLF
                     AGMIVVESGLSFLGFGISKAIPSWGNMLSDAQEGDVISGKPWIWMPPAIMITLTILSI
                     NFVGEGLKDAFNPRGRR"
     gene            complement(8951..9913)
                     /locus_tag="RFE25_002395"
     CDS             complement(8951..9913)
                     /locus_tag="RFE25_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817430.1"
                     /translation="MLKLILKRLGLMIPLLILISIVVFSLAIIQPGDPFSDLQNGKIK
                     QEAINAQREKLGLNDSIPHQYIRWVNHVIHGDLGESIKYKRPVIDVIEERIPNTILLG
                     AMSLIITYIISFALGITSGRYSYSLTDYTVQIFNYLMLAIPSFIAGVFAIFIFSFELQ
                     WFPFQGSVDINLKEGTFEYYMSKIYHTFLPALTLGLLSTAGYIQYLRNDIIENSKKDY
                     VLTARSKGLSMNKIYNKHILRNSLIPIITFLGADIVSILGGAVITETIFSYNGIGKLF
                     LESVIGQDYPLMMALTLFFSFLGLLGNLISDITYGFIDPRIRSN"
     gene            complement(9906..>10431)
                     /locus_tag="RFE25_002396"
     CDS             complement(9906..>10431)
                     /locus_tag="RFE25_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817431.1"
                     /translation="EFSGGQRQRVGIARALALRPSLIVADEPVSALDVSVQSQVLNLL
                     KDLQEQFKLSYLFIAHDLSVVKHISDVIGVMYLGHIVEIASDKEIYENPKHPYTKALI
                     SSIPQIDKHNNNRIILKGELPSPSNPPQGCPFHTRCPIAKDKCKENIPQLKDIGNEHQ
                     VACFYVDKVGDLNA"
BASE COUNT         3629 a         1736 c         1439 g         3627 t
ORIGIN      
        1 agaaatattt taaagacagt gtgcttttta agcaagtcaa ttactatatt gatacacccg
       61 atttcaaatt aaaggaacat cgctctgcac tacgcataag agttaaagac aatcaatatg
      121 aaatgacttt aaagacacca gcaaaggttg gtctattaga atacaactat atcgtcgaca
      181 ttaaaccaga gatgaacttg attatttcaa acgacaatct tccagatgac attcgtcaaa
      241 ttatagttga acagtttggt gtaaaagata caactttatc aatacttggt gcattaacga
      301 catatcgcca agaaactaaa tataaaggtg atttactcgt tttagataaa agtgagtatt
      361 tcgatactgc ggattatgag ttagagttcg aagttaaaga ctataatcaa ggtttacaaa
      421 agttccaatc tttattaaac gaactaaacc tcgaacatca tcaaccttta aataaagttc
      481 aacgtttttt caagaaaaaa gaaacacttt caaacaatat aaattaaatt ggcaaatatg
      541 catatttctt ccaaatgttt aaaatcatgt tatattagtt atatattaac ttaagttcgt
      601 aatagtaaat ttttgaaaat gggtgattaa atgacaacaa caccatatga catcattggt
      661 aaagaagcgt tatacgatat gattgattat ttttacaccc ttgtagaaaa agatgaacga
      721 cttaatcacc tgtttccagg agattttgca gaaacaagtc gtaaacaaaa acaattttta
      781 acacagtttt tgggcggtcc aaacatttat accgaagaac acggacatcc tatgctaaga
      841 aaaagacata tggattttac aatcactgaa tttgaaagag atgcatggtt agaaaatatg
      901 cagacagcaa ttaatcgcgc tgcgtttcca caaggtgttg gagattattt atttgagcgc
      961 ttaagattaa ctgctaatca tatggtgaat tcctaaaatt aattgtaggt gaataaacat
     1021 ggctggagaa ttacgaataa tggaaaataa gagtcgtgaa gatattaatc tatcacctgt
     1081 aagtaaaatc gaaatttatt catttttcga tccatttagc tccgattgct tcaaattatc
     1141 agcaatctta tccaaattaa gaattgaata taatcaatat atacgtatca gacatatatt
     1201 aaatccttcg ttaaaagtat taacgaaatg ccaagctcaa agtacatcca actttgataa
     1261 catcgcccta gcttataaag cagctgagtt acaaggtcgt gtacgtgccg aacgatttat
     1321 acatttaatg caaaatgaaa tcatacctaa aagagatatt attacagaat caatgatttg
     1381 tgactgtatt caaaatgcag gtattgattt agaagtattt aaagacgcct tacaaaaaag
     1441 taaactaacc gaaagcttga aaattgattt gcatattgca agagaaatgg aaatcgaaca
     1501 agccccttct ctcgttttct ttagtgaaga tgttcatgaa gaaggtttaa aagtcgaagg
     1561 attataccca tatcacatct atacttatat aattaatgaa ttgatgggta aacctatcga
     1621 aaagaatctt cctcctaaat tagaaactta tatacagcaa caacaacttg taacgatgga
     1681 agaattactt actatttatg aatggccaga aaaactttta aacaaagagt taaagaagtt
     1741 agccattcaa caaaaaattg aaaaacttaa atatccagac ggcgatttct ggaaatctaa
     1801 aatgcctaaa atcaaatcaa aataaataaa ttaaagacct cgtacaccat aaatgtaacg
     1861 aggtcttttt actgactctt aattttgcaa cattaaatta ttagaacgta atgttacaca
     1921 tcgatctaaa tatattagtg atatttttcg aatttaacca gttcgaaaat tatacaaatt
     1981 ataaatttgg tacataatag acttatatta atcgttaatg tataaaaagt gcatatttaa
     2041 tacattttta tacaacttca cttctctctt attaaaaaag aacataaaaa aacgtcgtgt
     2101 ctgaatacac gacgctaaac aaaggggatg ggagaaattt ttcacttcaa acaaaggggt
     2161 atgtttgtta tgtgattaat ttcatgttca taatataaca tgctatctct accatttcaa
     2221 ccttttaata gtacttaatt taaattgtca caatctgttc ataatgtaag cgaatacaat
     2281 agtactaagc tttcattaat ttttcaaaag cgttcaattt ttgttcaaaa acttcacaag
     2341 cttgttcaat tggttcaggt gttgtcatat ctacaccagc attttttaat atctcaattg
     2401 gataatttga gctacctttt ttcaagaatt cattaatata tctatctact gctggcttac
     2461 cttctgttaa aatttgatga cttaagcttt gagctgcact gtaaccagtt gcgtattgat
     2521 atacataata attcatatag aagtgtggaa tacgtgacca ttccttacta atatcttcat
     2581 cagtttctac agaatcaccg aagtataatt tatttaattt ggcatattct tcattcattc
     2641 tagttggcgt taatggttca cctgcttctt caattgcatg aattttatgc tcaaattctg
     2701 cgaacattgt ttgtcggaat aatgtagctc tgaaacgttc taattcttgg tttaataata
     2761 ataagcgttt ttcatcatca agatgtttat ccatataatc acttaaaagt gcttcgttac
     2821 aagttgatgc aacttcagcg acaaaaatag tgtagtcact agaatttgac ggttggaatt
     2881 ttctactgaa gtaactatgt gctgaatgcc caaattcatg aactaatgtg tataagtctg
     2941 aaatagtatt agaccagtta agtagaataa atggattagt taaatgtgca cctgatgaat
     3001 agccacctga acgtttacct ttattctcat agacatcgac ccaacgattg tttaagcctt
     3061 ctttaactac atttaaatat tcttcaccca ttggttctaa agcttttaac atccactctt
     3121 tagcttcttc ataaggcatt tcaaacttaa tatctttaat taatggtgta tataaatcat
     3181 acattttcaa gtcatctaaa cctagcaatt ctttgcgcaa ttcagtatat ctatgtagca
     3241 atggtaaata tttatgtaca gtttttacta gattgtcata tacattttct ggaatatgat
     3301 tattacttaa tgctttttct cttgcagttt tgtaattgtg tgtacgagca ttaaatacat
     3361 ttttcttcac ttcacctgct agcgtagcgc caagcgtatt attatgagca ccatatgctt
     3421 tatatacatt tctaaaagca ctttctctta gtttgcgatc atctgattct aaatacttaa
     3481 taaatgtacc ttgtgttaac gggtgtgcat ttccatcttt atcaatcgca tcttcaaata
     3541 ctaaatcagc gttgctaaac ataccgtata catttgatgg cgttgataac gcgtcctgcg
     3601 cttctgttaa taacttttca gtttcagcat ctaaaatatg aggacgtttt tcattaatca
     3661 acttcaaatc aaatgcgaat ttttgtaatt tatcatatga atttacaaat gattgaattt
     3721 tatcttcatc aatttgtaaa atctctggca ctaagaaact ccatgccgag ctaaatttaa
     3781 taattaattg atgtgctctt gactccatac cagtatactt gtcgttcgtt gtgtcttggt
     3841 cttgttttag gtgcgcgtat acatatactt tttctaattt agtacctaat gtatcttcta
     3901 attctaacgc attgtataat gtctcagcac tatcaccaat gtgtccttta aattgttctt
     3961 ctttgcctaa ctcattttca acttctttaa atgcagcctc aaaagcttca tcatctttga
     4021 aaattgttgt taagtcccat gtatattcag gatatttacg ttcctgttct tctctcgata
     4081 attgttgact catatgtagt aaacctccta ataaaatata attgatataa ttttctcatt
     4141 ttagaacaaa atttgcacgt cattacctct atctgaacaa atatttaaat aattgttaat
     4201 aagtttttct ataattgctg ttttactttc tagagcaaca ataaattttt tcagtttaaa
     4261 ataattaaga ttgtcattta ctaatttgct ttttccattc tttaaccata aatcaacttg
     4321 taattgccac tcaattggat gattttcaat ataaatttgc tctggaaaaa tataaccata
     4381 attgtacact acttcttgat cagttaactg taattgatac attgcactta aagtgggttc
     4441 taaaacagaa ttttgccagc gacaatattt gatatattga ttaattgcga actttgataa
     4501 tttataaaca gcatgataat cacaaggcgc ctcattaaac aactcaataa ttttggcatt
     4561 ccttttttca gcgacatatt tgtgcccgcc taaatattgt atttgttgaa acatcattat
     4621 ttgttttttc tctaaattga acgtatgaag ttttcgagtg attggattaa taaacaaact
     4681 atgaaaatga ttgaacttca ctttattatg acaataatca acatcattta ataaccaact
     4741 tactttatat cccattttct ttaaaccttc cgttcgttga agaatctgtt tataaggaat
     4801 tggcgaatac tgtagctcaa taacatattt attattaatc aaaatatccg gaatttgttt
     4861 tatttctttt aaaaatggct ctatctctac tttacatcct tgttgctgta tcatctgtgc
     4921 taaaatcaat ttacttttat aatgtttaat cgtttcatta ttaaaacatt tttgttccgc
     4981 taaatgttta tgtgcaaaat gactaattac tttgagccca cgctttaaaa taacttgctt
     5041 gccacacaca ggacaaaaat attgtgtctt tctcaatgca gtagttgcta acacacgttc
     5101 cttttcttca tttaaagcta ctaacatatc ttcacctcaa aatattacac gtaagtttaa
     5161 ctactattac tttttcagct tttgaaatca ataaaaaaag agactccaaa gagtctcctt
     5221 tcatagtgcg ttgcttaatt aatatcgtta ttcagttgtc tctggaaaat aacgtcgaac
     5281 ttgagctgtt acgttatgac tcataattat tttagcatag tcatttaaat aaacttctgt
     5341 tctgtctgtt ggatatgcaa attcaagcaa ttgactgtaa ctatcattaa tgacttcttg
     5401 atcaacatga ctatcaaaat gtacagcata ataataagta ccatcaacca tatataacaa
     5461 atcttcaaac tctgtagtta ttggattgct atgatatgca taattaataa catcttctaa
     5521 atcgttaaat ttcacaatga ttgttcttgt atttttacgt gctgaagact tttgacgttt
     5581 agaaccttga gcttcttttt cttttgttcg ttgctcgaat aattcttcta attgatcttc
     5641 accttctaat gtttgagcta acaattcttg aacttgttca tcaaattgat cagttgcatc
     5701 atcatcagac atattcatca tatcttcatt tttagattta gaaattgtga cttcgacacc
     5761 tttttcaaag gcatgtactt gaatccataa tggaccttct acaacaaaat cttcttcttc
     5821 gttaatttca tccatcattg accaaaagaa ttcttcgcca cgtttgcgat ttgtccataa
     5881 atcttcacga ctaaatccac gggcctcgat atcgctatat gttataaaca attttacagt
     5941 tgtatcatct actcgttcta ttctcatatc atctcactcc ttacagtcga tgaatagtat
     6001 ccacattgta ttaaagcatc aaacaaaata caatttattt gtttgatttc tttctctaaa
     6061 atattttggt aacttataat aacatattcg ttgtagcaaa actatttaaa tgatttatac
     6121 agttaaagca ttaaagcact ttcttaattt aattttacct tatcatagca aatgtttcat
     6181 ccaaaacact ctaatataga gctatattaa caattgcaca tttgatttaa aagatactaa
     6241 gcaattattg taaaattaaa accaaaaaag caacactata gaaatagtgt tgcttgacat
     6301 atcttttagt aaagtatgac acatagttaa atggttatta gtcaaccata cgttgtgctt
     6361 cttgtaattg gaacgtacga acttttctag gtaagaaacg tcgaatctcg tcctcattat
     6421 aaccaacttg tagtcgttta ttatctaaaa taattggacg acgtaataag ccaggattat
     6481 cttgaatgat tgaatataag tcttgtaatg gtagtgaacc aatatcaaca tttaattttt
     6541 ggtatgtttt agaacgtgta gaaatgattt catcagtacc gtcttcagtc atttttaata
     6601 tttgcttaat ttcatcaatt gttaaatgtt cagaaaaaat attacgctcc gtatacggaa
     6661 tgtcatgttc ttgtaaccat gctttcgctt tacggcaaga tgtgcaactt ggtgaagtaa
     6721 ataatgttac catacatctc actctcctat ttgaatgaat aaaattcatt gcttaaaatt
     6781 tagttataga tcaagaaaaa acattttttt ctaaaattct taatcgttac tatttattat
     6841 aactatctaa cattaaaatt aaatgagaaa aacctaattt ttcagataag tttctacact
     6901 tataaaaaag attattaatc ctttgttagt agtaagttat acgtatattc taacacatct
     6961 tacattttta agaaatactg ttataatgat aattattaaa atattactaa gaaagtaggc
     7021 atttaaatgg agacattatt ttcaggcatc caacctagtg gaattcctac tattggaaat
     7081 tatattggcg cactaaaaca atttgttgat gtgcaaaatg actatgattg ttatttctgt
     7141 atcgtagatc aacatgcaat tacaatgcca caagatcgtt taaaattacg taaacagacc
     7201 agacaattag cagcgattta tttagcttct ggtatagatc cagacaaagc aacattgttc
     7261 atacaatctg aagtccctgc acacgtacaa gcaggatgga tgttaactac gattgcttct
     7321 gttggagaat tagagcgtat gacgcaatac aaagataaag ctcagaaagc agttgaaggt
     7381 ataccagctg gtctattaac atatccacct ttaatggcag ctgatattgt tctttacaat
     7441 actaatatcg ttccagttgg agatgaccaa aagcagcata tcgaattgac tcgtaacctt
     7501 gtagatagat ttaatagtcg ctataatgat gtgcttgtga aacctgaaat tcgtatgcct
     7561 aaagttggtg gacgtgtcat gagtttacaa gacccaacaa gaaaaatgag taagagtgat
     7621 gataatgcta aaaacttcat ttcattattg gacgagccga atgttgcagc taaaaaaatt
     7681 aaaagcgcag taactgattc agatggtatt attaaatttg atcgtgacaa caagccaggt
     7741 ataacaaatt taatttcaat atacgctgga ttaaccgaca tgccaattaa agatattgag
     7801 gcaaaatatg aaggggaagg ttatggtaaa tttaaaggtg accttgctga aatagttaaa
     7861 gcatttttag tagaattcca agaaaaatac gaaagtttct ataactcaga taaacttgat
     7921 gatattttag atcaaggtag agataaagca cacaaagttt catttaaaac tgtcaaaaaa
     7981 atggaaaaag cgatgggatt aggacgtaag agataaaata aagaggtact agaattaact
     8041 agtgcctctt ttattattta acgtctacct ctaggattaa aagcatcttt aagcccttcc
     8101 cctacaaagt ttatacttaa tatagttaat gtaatcatta tagcaggtgg catccatatc
     8161 cacggtttac cacttataac atccccttct tgagcatcac tcaacatatt accccaagat
     8221 ggtattgctt tactaattcc gaatcctaaa aagctcaatc ctgattccac tacaatcata
     8281 ccggcaaata acaatgttgc ttgtacgata actacactta atatattcgg caaaagatgt
     8341 ttcaaaataa ttttatatgt gggtgtacca attgattttg ctgccaaaaa gtattcattt
     8401 tctttttctt gaagtacttt accacgaaca agtcttgcaa tacctcccca acttaatacg
     8461 ataataacta gaacaagaat tatggcagat ccataaggat ttttaatttt atctccaagt
     8521 gcagcattta atacaattgc aaatattaaa aatggaaata acataacaaa ttcggttatt
     8581 ctcattaata atgtatcaac aatacctcca aaataaccag aaatcactcc aactgtaatt
     8641 ccaatcaaaa gcattcctat tgtagatgta attccaatgg ataatgaaat acgacctgca
     8701 tataacaaac gactaaagtt atccctacca ccagagtctg taccaagaat gttttgtgct
     8761 gtcatttcac cttttatatt taataaatct tgttggttca ctggaaaagg agctattaat
     8821 ggcgctataa ttgatacaat agttatgatt aataaaaaaa taatcgataa cattgcaatt
     8881 ttattatgaa taaatctaga caatgcaatt ttaaaaggcg attttgactt attttgcatt
     8941 ccaatccccc ctagttactt ctaattcttg gatctataaa tccataagta atatcagaaa
     9001 tcaaattacc caataaacct aaaaatgaga aaaataacgt taatgccatc attaatggat
     9061 agtcttgacc tattaccgat tctaaaaata atttaccgat accgttatat gaaaagatag
     9121 tctcagtaat cacagctcca cctaaaatac ttacaatatc agcacctaaa aatgtaataa
     9181 taggtattaa agaatttctc aatatatgtt tattataaat tttattcata gataatcctt
     9241 ttgaccttgc cgtcaataca taatcttttt tagaattttc aataatatca ttacgtaaat
     9301 attgaatata accagcagta gataataatc ctaaagttaa tgcaggcaaa aatgtatgat
     9361 aaattttact catataatat tcaaaagtac cttctttaag gttaatatca acagaacctt
     9421 gaaacggaaa ccattgtaat tcaaaagaaa aaataaaaat tgcaaatact cccgcaataa
     9481 aagatggaat agctaacatc aaataattaa atatttgcac agtataatca gtcaaactgt
     9541 aagaatatct acctgacgtt attcctaaag caaatgagat aatataagta ataattaatg
     9601 acatagcacc gagtaatatt gtatttggaa ttctttcctc aataacatca attaccggcc
     9661 tcttatattt gattgactcc cctaaatcac catgtataac atgattgacc catctaatat
     9721 attgatgtgg tattgagtcg ttgaggccta acttttccct ttgtgcattt attgcttctt
     9781 gttttatttt accgttttgt aaatctgaaa atggatctcc tggttgtatg attgctaatg
     9841 aaaatacaac tattgagatt aaaattagta acgggatcat taaccctaac cttttaagta
     9901 ttaatttaag catttaaatc acctacttta tctacgtaga aacaagcaac ttgatgttcg
     9961 ttaccaatgt cctttaattg tggtatattt tctttacatt tatcttttgc aatcggacat
    10021 cttgtatgaa aaggacaacc ttgcggcgga ttacttggcg aaggtaattc tccttttaat
    10081 ataattctat tgttattatg tttatcaatt tgtggtattg atgaaattaa tgcttttgta
    10141 tatggatgtt tgggattttc ataaatttct ttatcagatg caatttcaac tatatgacct
    10201 aaatacataa ctccaattac atcactaata tgtttcacta cacttaaatc atgcgcgata
    10261 aataaatagc ttaacttaaa ttgctcttgt aaatctttta ataaattcag tacttgagat
    10321 tgaacagata catctaatgc acttacaggc tcatcagcaa caattaaact cggacgcaaa
    10381 gccaatgctc ttgcaattcc cactctttgt ctctgtccac ctgaaaattc a
//
LOCUS       DAPDIM010000079        10158 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000079 DAPDIM010000000
VERSION     DAPDIM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10158
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.079"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(280..1494)
                     /locus_tag="RFE25_002397"
     CDS             complement(280..1494)
                     /locus_tag="RFE25_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDU2817432.1"
                     /translation="MWVREITKNNSTAYRYLERYTDPLTGKYKTVSVTRNKNNVRSQK
                     DAQLELNKIIEQRLKHYSTKQLENLTFHDACDEWLEHYKTHSGSKPTTIKEKKSNTNT
                     VKNAIDSKVLISKITHTYLQNIINEWAKSHSIGHVQSLVIVIRSVFKYAFKYYDLHDI
                     SVLDKIDIPKKAQTRNEFQAKRNNYLEDSEVKELLECFDYLIKHKRHATRKRNYEMVK
                     ALVEFQINNGMRIGELLAIKTDNVDVENKTLEIDGTINWVTDVVTGAFGVKETTKTSK
                     SYRTIGLTAQSINLLKKLMLENKKENQWNDKFIDRGYIFTNTAGSPIDLNKVNNIIKE
                     ATDISSINKRVTTHTLRHTHISTLAQLGINLKAIQERVGHSDYKTTLEIYTHVTDKMA
                     KDMMNKLEGIGS"
     gene            complement(1655..2278)
                     /locus_tag="RFE25_002398"
     CDS             complement(1655..2278)
                     /locus_tag="RFE25_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2817433.1"
                     /translation="MVESNDELKKELGRFLKSIRKQKGKTASEISKQMQYSQGHISGI
                     ENGVKSFPSNKLIESYLMNIKDTNEEYNFYVDEIAKITKNKVKLNKVSNVTNKMEIID
                     RMMDIPYSREFISFDDNNEKSFTIFNISINDLHFHLQDINNYKFYKGIRLTDNDKNNI
                     DKILNNYFENKSVIIKENTKTLRDKNENWEQLVKLSDYIDDKLDKKN"
     gene            2427..2591
                     /locus_tag="RFE25_002399"
     CDS             2427..2591
                     /locus_tag="RFE25_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2817434.1"
                     /translation="MFMTVKEVAQLLRISERHTYKLLQKNVIPHTKIGGKILVNKERL
                     LETLEKKEVK"
     gene            2592..2864
                     /locus_tag="RFE25_002400"
     CDS             2592..2864
                     /locus_tag="RFE25_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002459646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HDU2817435.1"
                     /translation="MPRTKLQDFPSKENTVTEPEQVVVNPLFAKPNALAGIFGISYSS
                     VNRILKEWEKDHKGIDDLYYSLSSSMIVISIPRFEEYMKARHKKWM"
     gene            2876..3049
                     /locus_tag="RFE25_002401"
     CDS             2876..3049
                     /locus_tag="RFE25_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817436.1"
                     /translation="MKMYLTYICLVSLLTILLLAISNMYVAFSVYGMMVTYGFNLTGE
                     ITTCENKLLLQKQ"
     gene            3016..3219
                     /locus_tag="RFE25_002402"
     CDS             3016..3219
                     /locus_tag="RFE25_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817437.1"
                     /translation="MRKQVIITKTVVGWYNIKDTQHNLMLNIPPKVFEQYFPDVSKDV
                     QVACLEMDLSKITEIKNKKKVGS"
     gene            3221..3604
                     /locus_tag="RFE25_002403"
     CDS             3221..3604
                     /locus_tag="RFE25_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817438.1"
                     /translation="MEIKQKYQLSKVVKILEVVLYEEDKFQSDKDYHYQDKAFYEYAL
                     KLVHNGLFNILAELDFEDEVFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTD
                     RKGHVIGMLEWALDYIVGNIEVEVL"
     gene            3605..3931
                     /locus_tag="RFE25_002404"
     CDS             3605..3931
                     /locus_tag="RFE25_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1474 family protein"
                     /protein_id="HDU2817439.1"
                     /translation="MNWEINDLFSDLKLLKDRFEDLKDNHGWHFEELYPHEPNHNLNK
                     DELIREGASYHERRIHNNQMFDLFHLYIEQFDNIIEKFYEIEKASSENFGEESDDAKN
                     SIKVAE"
     gene            3996..4865
                     /locus_tag="RFE25_002405"
     CDS             3996..4865
                     /locus_tag="RFE25_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017636850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HDU2817440.1"
                     /translation="MNEIKLEYDTHVSVVHYESLDSRSFNSFSKPKWSKLVNKLSVPI
                     EANYKYARGVAIYGDMKDDTDENGNEYKKYRKDENVIYRDVLVLDYDDIPKLRILHDA
                     ITETLKGVSWMYHTTFNHRTESPRVRLYIALNEHISADEYRKYTKVLESKIGHPVDEG
                     SYQPSRAMALPVKKSNDSIYIFKYNDAPILSVETLEEWSKELKSQYKESNKFKYPKRR
                     DNEFWKSIAFGVSTGNRNQMLTSLIGVLLNRRVPDPLVYAYCFMWNENCNPPLSSREF
                     NATFESIYKREHR"
     gene            4877..6247
                     /locus_tag="RFE25_002406"
     CDS             4877..6247
                     /locus_tag="RFE25_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002501457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HDU2817441.1"
                     /translation="MTIFPDFLENKTMFDEKDFFDGNKFKFYEFALFLYEEYHGCYID
                     NRPHVFTGKKYEPLNIDVVRKITIKYIPSLREQQNKEVFQKLKTLCLGNHQEQCPARY
                     IGLKNGIYDTVEERLNPFSPQYYITNIIDVDFDKGAQSDLIERFIKDISNEDEEVEQL
                     IYEMIGYGLYRDNFLQVAFFYYSPGGNGKTTLLKLLHHFYNPENTTALSFNDLNDKFK
                     PANLQGKLVNIADDIDPNRIKDTGNFKIIVTGNYITLEFKGQDAFEFKPYVKLIFASN
                     ELPMSNDKSEGFYRRMVIIPMLRKFGKGGQKKDPMLLNKLITPHNMSALLNLALKGLK
                     RTLENNEIIEPKIARKTKEEYQFENNPVLQFIEDATDKDYRQLPVVEGRNTDKAYEIY
                     QIWCVNNGYHHLNKFNFSKELAKIGYKTVSYYSRVEEKSKRFYKKENTINIYDVDGSI
                     LKKLTE"
     gene            6490..6846
                     /locus_tag="RFE25_002407"
     CDS             6490..6846
                     /locus_tag="RFE25_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817442.1"
                     /translation="MNNIKGELVNYIKNNAGTSFVEIEKVFDENAFDYKGQGAYTSAV
                     NNNIVYWYGWNKQAFNLVSDLVNDGVIEMNICESIIYIVDGKGLNFPILKSDDVDTYH
                     WLPVTFTISKKEMECV"
     gene            6848..7111
                     /locus_tag="RFE25_002408"
     CDS             6848..7111
                     /locus_tag="RFE25_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001804819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817443.1"
                     /translation="MNEKHNIFNRFGRNTSIQTVAVKDTYFIEYRKGDEIKYFPIELA
                     TVVKALNIDLHDSDTVSNYENGPKFDIKKLNLYTGDMDQIGDE"
     gene            7113..7754
                     /locus_tag="RFE25_002409"
     CDS             7113..7754
                     /locus_tag="RFE25_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012990921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817444.1"
                     /translation="MNIEIIANQFVTRAGTLLRYYTGLLEHSKVQPYCFKLYNDPFDM
                     CYVVMNSKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISD
                     MMASQLFEDEYFMYGLQTYVESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLY
                     QLATGINEPARELVEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK"
     gene            8462..8806
                     /locus_tag="RFE25_002410"
     CDS             8462..8806
                     /locus_tag="RFE25_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817445.1"
                     /translation="MSEFEVKEKTYNLPNEHRQVLNVIRNTSNKYITKTKLLNQLGYE
                     YNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGS
                     MKRYEALKRIEV"
     gene            8837..9490
                     /locus_tag="RFE25_002411"
     CDS             8837..9490
                     /locus_tag="RFE25_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817446.1"
                     /translation="MTTTTITGDTWDVYFNDRRYRNLLGDFEDLITETKSLIRQGYKT
                     DVIKNKMDNKALSLQSKFKELGQILLDEHEEKIVEIQQKEKESSYENPQVEMLKRQDI
                     EAKVNLIDAEELFNLVYNANPKTTNVYELNIYKKAIESRLTEDENVRLKPYFDVLVEK
                     VIYPYRNNEEYQKLEYNYNVLRQFGLQNNGQPVIKHSDGDIEIINIQSKYNEVFRNA"
     gene            9543..10070
                     /locus_tag="RFE25_002412"
     CDS             9543..10070
                     /locus_tag="RFE25_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDU2817447.1"
                     /translation="MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQI
                     ESMYHLSASTTTCDEIMGIVSVSYPIEKLVIKIIETNARLQNYKNRSISNMVLLKTVL
                     NHYTEKEQKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNIAIENSKI
                     ARVNAYHQSSHVKVV"
     gene            10073..>10158
                     /locus_tag="RFE25_002413"
     CDS             10073..>10158
                     /locus_tag="RFE25_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817448.1"
                     /translation="MDKQQIKGFVCDYHERTRSDVLIDDDINT"
BASE COUNT         3690 a         1321 c         1815 g         3332 t
ORIGIN      
        1 ggtacaactg ttactaaaga attatatgga ctatcatttt tgtttaatac tattccaaaa
       61 tgtctgccag aaaattcatg cccaatattg atgccaaaat ctaaatatat aatagatccc
      121 cttgagaatt ttttgtattt tttgtttata ttgttattat gctccatatt aaaccaatat
      181 gatgttgtct ctaaccaatt tggtaaaaat ttaaactttt tattatctgt gttatataac
      241 agaataaata ctcacagctt tatttattct gttatccatc taactcccta tcccctctaa
      301 tttattcatc atatcttttg ccatcttatc agtaacatgt gtgtatatct ctaaggtggt
      361 tttatagtcc gagtgaccta cacgctcttg tatcgctttt aggttaattc ctaattgcgc
      421 aagtgtagat atgtgtgtgt gacgtaatgt gtgcgttgtc acacgcttgt taattgaact
      481 tatatcagta gcttctttaa taatattatt caccttattt aagtcaatag ggctaccagc
      541 agtgttagta aatatataac ctctatctat gaatttatca ttccactgat tctctttttt
      601 attttctagc atgagttttt taagtaaatt aatactttga gctgtgaggc ctattgttcg
      661 ataactctta ctcgtcttag tcgtttcttt cactccaaat gctccagtta ctacatctgt
      721 aacccagtta attgtgccat caatctctag tgttttattc tccacgtcta cattgtctgt
      781 cttgattgct aggagttcgc caatgcgcat tccattgtta atttgaaatt ctactaatgc
      841 ttttaccatt tcatagttac gtttacgcgt agcatgacgc ttatgtttaa ttagatagtc
      901 gaagcactct agtaactcct ttacttcgct atcttctaaa tagttattac gtttagcttg
      961 aaactcgttt ctggtttggg ctttcttagg tatatctatt ttatctaaca cactaatatc
     1021 gtgcagatca taatatttaa acgcatattt gaaaacggaa cgaataacaa taacaagaga
     1081 ttgaacatgg ccaatactat gtgatttagc ccattcatta atgatgtttt gtaagtaggt
     1141 gtgcgtaatc ttgctgatga gtactttgct atcaatagca tttttaactg tattagtatt
     1201 acttttcttt tctttaatag tggttggttt cgagcctgaa tgtgtcttgt aatgctctaa
     1261 ccattcatcg cacgcatcat ggaacgttaa gttttcaagt tgtttcgtac tgtaatgttt
     1321 caaacgttgc tcaattattt tatttaattc taattgagcg tccttttggc tacgtacatt
     1381 attcttgtta cgtgtaactg atactgtttt atacttgcca gttaaagggt ctgtatagcg
     1441 ctctaaatag cgataggccg tactattgtt tttggtgatt tcacgaaccc acatttgtca
     1501 tccctccttt agatattctg tttttaaaat gtctgaaata aacaagtaac tatcaagtgt
     1561 agtacaaaat aggcaaagtt acgtatgttt ataggattgt acggtagtaa tatttgtagt
     1621 attagcttta agtatttatt ttagcgtgct ttgttcagtt ctttttatct aacttatcat
     1681 ctatataatc gcttaatttt actaattgtt cccagttttc atttttatct cttaaagttt
     1741 ttgtgttctc ttttataata actgatttat tttcgaaata attatttaaa attttatcga
     1801 tgttattttt atcgttatcc gttaatctaa tgcctttgta aaatttataa ttattaatat
     1861 cttgcagatg aaagtgcaaa tcattaatgc taatgttaaa aattgtgaaa ctcttttcgt
     1921 tattgtcatc aaaagatatg aattctctag aatatggtat atccatcatt ctatctataa
     1981 tttccatttt atttgttaca ttagaaactt tgtttaactt aactttattt ttcgttatct
     2041 tagctatttc atcaacataa aaattatact cctcattagt gtcttttatg ttcattaagt
     2101 aactttcgat aagtttattg cttggaaaag atttaacacc attttcaatg ccacttatat
     2161 gcccttgaga atactgcatt tgtttactta tttcgcttgc tgtcttccct ttttgttttc
     2221 ggatagactt taaaaatctg cctaattctt tttttaattc atcatttgat tcaaccattg
     2281 gcgacacctc cgtattttta atgataaacc atgcataaaa ataatacaat attattcttg
     2341 acattcctaa aagaaggtgc gatactctat ttatgcataa aggaataaaa ataaatgcat
     2401 atattcttaa ggtgaggggt gattttatgt ttatgactgt aaaagaagtt gctcaattgt
     2461 tacgtataag tgaacgccat acttataaac ttcttcaaaa aaacgttata ccacatacta
     2521 aaattggcgg aaagatatta gttaacaaag aaaggttatt agaaacttta gaaaaaaagg
     2581 aggttaaata aatgcctaga acaaagttac aagattttcc atcaaaagaa aatacagtta
     2641 cagaaccgga acaagttgta gtaaatccgt tgtttgcgaa acctaatgca ctagctggta
     2701 tttttggaat ttcatacagt tcggtcaatc gtattttaaa agagtgggaa aaagatcata
     2761 aaggtattga tgatttatat tattcactat catcatcaat gattgttatc agtattccgc
     2821 gattcgagga gtacatgaag gcgcgtcata aaaaatggat gtaggaggca aggcaatgaa
     2881 aatgtactta acttatatct gcttagtttc attgttaaca attttattac tagcaatatc
     2941 taacatgtat gtcgctttta gtgtgtacgg catgatggta acttatggat ttaatttaac
     3001 aggagagatt acaacgtgcg aaaacaagtt attattacaa aaacagtagt tggctggtac
     3061 aacattaaag atactcaaca taatttaatg ttaaatatac cgccaaaagt atttgaacag
     3121 tactttcctg atgttagtaa agatgttcaa gttgcgtgtt tagaaatgga tttatcaaaa
     3181 attacagaaa ttaaaaataa gaaaaaggta ggtagttaag atggaaatca aacaaaaata
     3241 tcaattatca aaagtggtta aaatattaga agtagtatta tacgaggaag ataagtttca
     3301 atccgataag gactatcatt atcaggataa agcattttat gaatatgctt taaagttagt
     3361 tcataatgga ttgttcaata ttcttgctga attagatttt gaagatgaag tatttttaat
     3421 tcttgatgaa gtaacgatga cgctaagtga tgtcatgaaa gaaacacaac acgtttatcg
     3481 ttatagtgtc atagacgaaa aaggtgaaca taaacataca acagatcgca aaggacacgt
     3541 gattggaatg ttagagtggg cattagatta cattgtggga aatattgaag tggaggtatt
     3601 ataaatgaat tgggaaatta atgatttgtt tagcgatttg aaattgttga aagatagatt
     3661 cgaagattta aaggataatc atggttggca ttttgaggag ttatatccac atgaaccaaa
     3721 tcataactta aataaagatg aattaattag agagggtgct tcttatcatg agagacgtat
     3781 tcacaataat caaatgtttg atttattcca tctctatata gagcagttcg ataatattat
     3841 cgaaaagttt tatgaaatag aaaaagcatc atctgagaac tttggcgagg aatcagatga
     3901 cgcaaagaat tcaataaaag tagcagagta atatagaaat tacacattct tattataaca
     3961 tctttgctct gttgtttcat taagaggtgc aaaaaatgaa tgaaattaaa ttagaatatg
     4021 acacgcatgt ttcagtggta cattatgaaa gtttagactc acgttcattt aatagctttt
     4081 caaaacctaa atggagtaag ttagttaata aactatctgt acctatagaa gcgaattata
     4141 agtatgctcg tggtgttgct atatacggtg atatgaaaga cgatactgat gaaaatggta
     4201 atgaatataa gaaatatcgt aaagacgaaa atgttattta tcgtgatgtc ctagtgctgg
     4261 actacgatga tatacctaag ttaagaatac tacatgatgc aattacggag actttaaaag
     4321 gtgtttcctg gatgtaccac actacattta atcatcgaac agaaagtcct agagtacgtt
     4381 tgtatattgc tttgaatgag catataagtg cagatgaata ccgtaaatat acaaaagtgt
     4441 tagagagcaa gataggtcat ccagtggacg agggaagtta tcaacctagc agagcgatgg
     4501 cgttaccagt aaagaaatca aacgattcaa tttacatctt taaatataat gatgcaccga
     4561 ttttgagtgt tgaaacgcta gaagaatggt caaaagagct taaatcacaa tataaagaat
     4621 caaataaatt caaatatcct aagcgtcgtg ataatgaatt ttggaagtca attgcttttg
     4681 gggtctcaac aggtaaccga aaccaaatgt taacatcgtt aattggtgta ttgctaaata
     4741 gacgtgtacc cgatccgtta gtatatgcat attgctttat gtggaatgaa aattgtaatc
     4801 ctccattgag ttctagagag tttaacgcca catttgaatc tatatacaaa cgagaacatc
     4861 gataaggagg tattttatga caatatttcc agactttttg gaaaataaaa caatgtttga
     4921 tgaaaaagat ttctttgacg gtaataaatt taaattttat gaatttgcct tgtttttata
     4981 tgaagaatat cacggttgct atattgataa ccgtccacat gtgttcactg gtaagaaata
     5041 tgaaccacta aatatagatg ttgtccgtaa gattaccatt aaatatattc catccttgag
     5101 agaacaacaa aataaagaag tgtttcagaa gttaaaaact ttatgtttag gtaatcatca
     5161 agaacaatgt ccagcacgtt atataggttt aaagaatgga atatatgaca ctgttgaaga
     5221 aaggttaaat ccttttagtc ctcaatacta tataaccaat attatagatg ttgattttga
     5281 taaaggtgct caaagtgatt tgatagaaag attcatcaaa gatatttcaa atgaagatga
     5341 agaagtagaa caattaatat atgaaatgat cggctacggt ttataccgtg ataatttcct
     5401 acaagttgct ttcttctact atagtcctgg tggtaatggt aaaacaacat tacttaaatt
     5461 attgcaccat ttctataatc cagagaatac gacggcgtta tcttttaatg atttaaacga
     5521 taagttcaaa ccggccaact tacaagggaa attagtgaat attgcggatg atattgatcc
     5581 aaatagaata aaagatacag gtaactttaa gattattgtg actggtaact acattacact
     5641 tgagtttaaa ggacaagacg catttgagtt taagccttat gtaaaactta tatttgctag
     5701 taatgaatta ccaatgagta atgataagag tgaaggtttt tatagacgta tggtaattat
     5761 tcctatgttg cgtaagttcg gcaaaggtgg gcagaaaaaa gatccaatgt tattgaacaa
     5821 attgataaca ccgcataata tgtcagcctt acttaattta gctttaaaag gtttaaaaag
     5881 aacattagaa aataacgaga ttatcgaacc gaaaattgct agaaagacaa aagaggaata
     5941 tcaatttgag aataatccag ttttgcagtt catagaagat gcgacagaca aggattatag
     6001 acaattgcca gtagtagaag ggcgtaatac tgataaagca tacgaaatat atcaaatatg
     6061 gtgtgtgaat aacggttatc atcatcttaa taaattcaat ttttctaaag aattggcgaa
     6121 aattggttat aaaacagtta gctattattc aagagtagaa gaaaaaagta aaagatttta
     6181 taaaaaagaa aacaccataa atatatatga tgttgatggt agcatattga aaaagctcac
     6241 agaataagtg tgagtaaatt tatataagtg tgagattaca aacattaata tatcaatact
     6301 tttaaaggtt ttctcacacc tcacacttta ttttaacttt aaaacagata aatcgttata
     6361 tgaattatat atgttcaatt acttaattta tctgtgaggt gtgagaaata agttgtaaca
     6421 cttgatatta aagcgtttat atcattacaa gtaagtgtga gaaaaaagaa tatactgtga
     6481 ggttttgaaa tgaacaatat aaaaggtgag ttagtaaatt atattaaaaa caatgctggt
     6541 acatcatttg tagaaataga aaaagtgttt gatgaaaacg cctttgatta taaaggtcaa
     6601 ggagcataca caagtgcagt gaataataat attgtgtatt ggtatgggtg gaataaacaa
     6661 gcatttaatt tagtaagtga tctagtgaat gatggtgtta tagaaatgaa tatttgtgaa
     6721 tcaattattt atatagttga tggtaaaggg cttaatttcc ctattttaaa gtcagatgat
     6781 gtagacacat atcattggtt acctgtcacg tttactatta gtaagaaaga aatggagtgt
     6841 gtttaaagtg aatgaaaaac ataatatttt caatagattt ggtagaaaca cttctattca
     6901 aactgtagca gttaaagata cttactttat tgaatatcga aagggagacg aaataaagta
     6961 tttcccaata gaacttgcta cggtagtaaa agcattaaac attgatttac atgacagtga
     7021 tactgtttca aattatgaga atgggccaaa atttgatatt aaaaaattga acctctatac
     7081 aggtgacatg gaccaaatag gagatgaata aaatgaatat agaaattatc gcaaatcaat
     7141 ttgtaacaag agcaggcacg ttattaaggt actacactgg attattagaa catagtaaag
     7201 tacaaccgta ttgctttaag ttatataatg atccgtttga tatgtgttat gtggtgatga
     7261 atagtaagtt gtttggtcat gtatatatta aagattgtaa agtaaggcaa tcgtttgaat
     7321 tagcgtcacc taagcacact gaggggctta taagaagcat agaggggcat tatgtaggtt
     7381 atgaattaca tgatggtaaa cagctttcta ttagtgatat gatggccagt caattatttg
     7441 aagatgagta ttttatgtat gggctacaaa catatgtaga atcaaataat agtgatgtgt
     7501 ttgagtacct agaaaatgga tttgatacag atacacttga gggcattcaa tcaagtaata
     7561 ctgatgtgat agcgaatatt gaaatgttgt atcagttagc tacgggaatc aatgaaccag
     7621 cacgagagtt agttgaggga ttaaaattag taactgagtt tgtacaagat gagaatgcga
     7681 cacaagagga ttacaaggcg ttagaacgta aattgaatga tctaaaagcg tcttactata
     7741 gcttgagtaa ataatgttat gaggggtcac atgtagtgtg tggctcctaa taaaaaaacg
     7801 gcaaggtttg tacaaggtat agaagtttaa aatggtaagg ttttcggaag gtgttggctt
     7861 ttaaaatcca aaagtttccc aaaggtgcgc agactctgag aacaatgaaa taggaaggtg
     7921 tacaaggtta aaaaagcgag gtacagaact ttaaaatagt aagtttgagg tagaaagaaa
     7981 acaatgtttt ataccagggt tgcaaaatgg tgagaaaagg gataaatgcg agcaattgaa
     8041 tcaagaagaa gtgaaaaccc caagattttc cgtaggttat aagaatagtg cgattttaga
     8101 taggtacgaa gaattgcgtc aagaaggaaa ctaaaggtaa gtggtttttg atattgataa
     8161 aagtaataag gttttaataa ggtataaaaa atttaaaaag ataatatatg ttaatgtttg
     8221 ttatttttga aaagggcaaa agttttattg ttcgtatttt gttcgtgtaa aaaatgggaa
     8281 cttaagttct atagaaatta atacgtttta ctacaaaatt tcttttcctt atttttttaa
     8341 gagggatagg ggtgatgcta aacgcctgat ataatgcgat ttatagcgaa cataagtttg
     8401 atttagatgt gtagaattgg tataattaga gtaagcaaac aacagaaagc atggtgagac
     8461 aatgagtgaa tttgaagtaa aagaaaagac gtacaactta ccgaatgaac accgccaagt
     8521 actcaatgtg ataagaaata cgtctaataa atatattact aaaacaaagc tgcttaatca
     8581 attgggatat gaatataatt caagcaatga acgatggtta cgaagagtaa tcaattcatt
     8641 agtatatgat tatggttatc ctatcggatg cagttataaa cctagtgaac gtggttatta
     8701 catcattacg acagaacaag aaaagcaaca agcgatgaga agtattaaga aattagctga
     8761 tggcagtatg aaacgctatg aagctttgaa acgaattgaa gtgtaaaaca aaaactaaag
     8821 aaagaggtac ttataaatga caactacaac aatcacgggt gatacgtggg atgtatattt
     8881 taatgataga cgttatagaa atttgttagg agattttgaa gatctaataa cagaaacgaa
     8941 atcattaatt agacaaggct ataaaacgga tgttattaaa aataaaatgg ataataaggc
     9001 tttgagccta caatctaaat tcaaagaatt aggacaaata ttattagatg aacatgaaga
     9061 aaaaatagta gaaatccaac aaaaagagaa agaatcttca tatgagaatc cacaagttga
     9121 aatgttgaaa cgtcaagaca tagaggcgaa agtaaattta attgatgcag aagaactatt
     9181 taatcttgtt tataatgcca atcctaaaac cactaatgta tatgaactta atatctataa
     9241 aaaagcgata gaaagtcgtc ttactgaaga tgaaaatgta aggttaaaac cttactttga
     9301 tgtattggta gaaaaggtaa tttatccata tcgaaataat gaagaatatc aaaaattaga
     9361 gtataactat aatgttttaa gacagtttgg gttacaaaat aacgggcaac cagtcatcaa
     9421 acatagtgat ggcgatatag aaattattaa cattcaaagt aagtataacg aagtgttccg
     9481 taacgcttaa atcaaaaata gcctatccaa tttgggtagg ctctctttat aggagtgaac
     9541 gtatgaaact gcttaaaacg aagaattgtt tatattatcg taatggcgac aataaattat
     9601 ctgagtatca actattaacg caatttaacc cagcatttat taataaaaaa attaagatgt
     9661 gtgaattcca aattgaaagt atgtaccatc tgagtgcgtc gaccacaaca tgtgatgaaa
     9721 taatggggat cgtgtctgtc tcatatccaa ttgaaaaact agttatcaaa attattgaaa
     9781 caaacgcaag attacaaaac tataaaaatc gatctataag taatatggtg ttgttgaaaa
     9841 cagtactaaa tcattataca gaaaaagagc agaagcaagt tgtaaaatat atgcgttcaa
     9901 atggacgata taagccctac aatgtcattg aacgcttaca ggttgatttg tatcaagcaa
     9961 gtattaaaca acgttcagaa cgtcaaaaac aaagaaatat agcaattgaa aatagcaaga
    10021 ttgcacgagt aaatgcttat caccaatctt cacatgtaaa agtggtgtaa caatggataa
    10081 acagcaaata aaaggcttcg tttgtgatta tcatgagcga actagaagtg atgtattaat
    10141 agatgatgat ataaatac
//
LOCUS       DAPDIM010000080         9768 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000080 DAPDIM010000000
VERSION     DAPDIM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9768
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.080"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(322..876)
                     /locus_tag="RFE25_002414"
     CDS             complement(322..876)
                     /locus_tag="RFE25_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase family protein"
                     /protein_id="HDU2817449.1"
                     /translation="MTDVIIVHSMHGNSRNHWYQWLEHNLTLEGYDVTLFNFESPEAK
                     TVDQWIEAMTKQINVRKKDTYFVTHGLGSITALKYIEMIDQPIEGFFSIAGFKEDAEN
                     IDLDIDLSNVTIDYDNIKKKVDNFYGLSSKNDKYVSYKETQRLMNALEGNLRIVEDGG
                     HFLEEDGFETFTALQDRMQDYMTR"
     gene            complement(1199..2599)
                     /locus_tag="RFE25_002415"
     CDS             complement(1199..2599)
                     /locus_tag="RFE25_002415"
                     /EC_number="1.3.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoporphyrinogen oxidase"
                     /protein_id="HDU2817450.1"
                     /translation="MTKSVAIIGAGITGLSSAYFLKQQDPNIDVTIFEASNRPGGKIQ
                     SYRKDGYMIELGPESYLGRKTIMTELAKDIGLEQDIVTNTTGQSYIFAKNKLYPIPGG
                     SIMGIPTDIKPFVTTKLISPLGKLRAGLDLIKKPIQMQDGDISVGAFFRARLGNEVLE
                     NLIEPLMGGIYGTDIDKLSLMSTFPNFKEKEEAFGSLIKGMKDEKNKRLKQRQLYPGA
                     PKGQFKQFKHGLSSFIEALEQDVKNKGVTIRYNTSVDDIITSQKQYKIVYSNQQEDVF
                     DGVLVTTPHQVFLNWFGQDPAFDYFKTMDSTTVATVVLAFDEKDIENTYDGTGFVIAR
                     TSDTDITACTWTSKKWPFTTPEGKVLIRAYVGKPGDTVVDDHTDNELVSIVRRDLSQM
                     MTFKGDPEFTIVNRLPKSMPQYHVGHIQQIRQIQAHIKQTYPRLRVTGASFEAVGLPD
                     CITQGKVAAEEVIAEL"
     gene            complement(2623..3546)
                     /gene="hemH"
                     /locus_tag="RFE25_002416"
     CDS             complement(2623..3546)
                     /gene="hemH"
                     /locus_tag="RFE25_002416"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HDU2817451.1"
                     /translation="MTKKMGLLVMAYGTPYKESDIEPYYTDIRHGKRPSEEELQDLKD
                     RYEFIGGLSPLAGTTDDQADALVSALNKAYADVEFKLYLGLKHISPFIEDAVEQMHND
                     GITEAITVVLAPHYSSFSVGSYDKRADEEAAKYGIQLTHVKHYYEQPKFIEYWTNKVN
                     ETLAQIPEEEHKDTVLVVSAHSLPKGLIEKNNDPYPQELEHTALLIKEQSNIEHIAIG
                     WQSEGNTGTPWLGPDVQDLTRDLYEKHQYKNFIYTPVGFVCEHLEVLYDNDYECKVVC
                     DDIGANYYRPKMPNTHPLFIGAIVDEIKSIF"
     gene            complement(3604..4641)
                     /gene="hemE"
                     /locus_tag="RFE25_002417"
     CDS             complement(3604..4641)
                     /gene="hemE"
                     /locus_tag="RFE25_002417"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HDU2817452.1"
                     /translation="MVHNKNNTILKMIKGEETSHTPVWFMRQAGRSQPEYRKLKEKYS
                     LFDITHQPELCAYVTHLPVDNYHTDAAILYKDIMTPLKPIGVDVEIKSGIGPVIHNPI
                     KTIQDVEKLSQIDPERDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSK
                     NYNFTKAMMYRDEATWFALMNHLVDVSVKYVTAQVEAGAELIQIFDSWVGALNVEDYR
                     RYIKPHMIRLISEVKEKHDVPVILFGVGASHLINEWNDLPIDVLGLDWRTSINQAQQL
                     GVTKTLQGNLDPSILLAPWNVIEERLKPILDQGMENGKHIFNLGHGVFPEVQPETLRK
                     VSEFVHTYTQR"
     gene            complement(4631..4741)
                     /locus_tag="RFE25_002418"
     CDS             complement(4631..4741)
                     /locus_tag="RFE25_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817453.1"
                     /translation="MIKCQFYDIYLLKIRTNERYDNIDKNDFNLGGLYGA"
     gene            4904..5407
                     /gene="traP"
                     /locus_tag="RFE25_002419"
     CDS             4904..5407
                     /gene="traP"
                     /locus_tag="RFE25_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein TRAP"
                     /protein_id="HDU2817454.1"
                     /translation="MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGE
                     TVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKS
                     YRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFER
                     YLYPIKE"
     gene            complement(5531..6754)
                     /locus_tag="RFE25_002420"
     CDS             complement(5531..6754)
                     /locus_tag="RFE25_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817455.1"
                     /translation="MHNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFI
                     FGYGEWLKHIPTNINFALIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHA
                     ILYSYFARILIQLIIVIVMFPLFYNINQHNVAFYICFGFSALIFPYVGLRLRWQWYQS
                     GLKTWQVNLISFIIFALTYYLLLAPKWYIVFVMVALPVLIEFLVKKYKPGFLYPWEKM
                     IAIEHRHHMNYYKFVNMFTDVKHLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIR
                     SFIRGRDAFNIIFRLVIIAVLLMVWLSYPLVTGVIGSLFVYIILLQMAQFYSQQAYGL
                     WPQVWPVPEEKVIKGYEQFLYRLMFVICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIR
                     SIIKKLKYQETLLRD"
     gene            complement(6747..7487)
                     /locus_tag="RFE25_002421"
     CDS             complement(6747..7487)
                     /locus_tag="RFE25_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817456.1"
                     /translation="MTVKVEQLTGGYGKRPVIKDINFELNKGEIVGLIGLNGAGKSTT
                     IKHMLGLLTPMEGSLSISDININDDIEAYRRKLSYIPESPVIYEELTLEEHIEMTAMA
                     YDIDRDEAMNRAMPLLKTFRLENELKVFPSHFSKGMKQKVMIICAFIVNPELYIIDEP
                     FLGLDPLGIQSMLDLMVEKKNEGRIVLMSTHILATAERYCDRFIILDEGEVVAFGDLE
                     ALRQQTGLHNQTLDDIYIHVTQGGDVHA"
     gene            7621..8043
                     /locus_tag="RFE25_002422"
     CDS             7621..8043
                     /locus_tag="RFE25_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HDU2817457.1"
                     /translation="MSETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPK
                     KASANIFETDEETMKHIGAALPKVANAIKRAFNPDGLNIIQNNGEFADQSVFHIHFHL
                     IPRYENDIDGFGYKWETHEDILDNDAKQQIAEQIQAQF"
     gene            8185..8550
                     /locus_tag="RFE25_002423"
     CDS             8185..8550
                     /locus_tag="RFE25_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDU2817458.1"
                     /translation="MKASRILFGIGVGVAAGFVVALQGRDDKSVKNNTIDRTAPTGSK
                     SELQREFETIKQSFNDILNYGVQIKNESAEFGSSIGGEIKSLLGNFKSDINPNIERLQ
                     SHIENLQNRGEDIGNEISK"
     gene            9285..>9768
                     /locus_tag="RFE25_002424"
     CDS             9285..>9768
                     /locus_tag="RFE25_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3267 domain-containing protein"
                     /protein_id="HDU2817459.1"
                     /translation="MFLCKRQIDINARFGLPRIAFMSAVATIIMFLVSYEVMYFLSNT
                     PLSDRHFLIFLLLVFMTYPLHKSIHLLFFLPYRKSFKVHKLTKRKWLIFYNTYVNQPV
                     HKFYFCINLILPLIILSAMFVYLTISFPQYGHYFMFLLALNFGISITDLLYLKIIIFS
                     N"
BASE COUNT         3195 a         1771 c         1343 g         3459 t
ORIGIN      
        1 tattatttct taaataatta cttaaatatc gtagcaacat gttctctgtt gaacacaaat
       61 attagtatat tcatttttgt agtgtacgtc aacgacattt tgaaagtttt ttgtgtaaaa
      121 aaacgcttct tcttcccttt tataatataa gtgtctaata gttgtcataa ttactcatga
      181 actattgaaa aagatgtagg aatcataaat tttataatgc ctacacctct aaactattaa
      241 aatataatta taatcttttt cactaaagtg ctatgcttcg tactgacaca cataacacaa
      301 tacatagcaa ccaaacatta cctatcgtgt catgtaatct tgcatccgat cttgcaacgc
      361 tgtaaatgtt tcgaagccat cctcttctaa gaagtgccct ccatcttcca cgattcgcaa
      421 gttcccctct aatgcattca ttaaacgctg ggtttcttta tatgaaacgt atttgtcatt
      481 tttagaactc aatccgtaaa aattgtcaac tttcttttta atattatcgt aatcaatggt
      541 tacattactt aaatcaatat ctaaatctat attttctgca tcttctttaa agcccgctat
      601 actaaaaaag ccttcaatcg gctgatcaat catttcaata tattttaaag ctgtgattga
      661 acctaaacca tgtgttacaa aatatgtatc ctttttgcgt acattaattt gtttcgtcat
      721 agcttcaatc cactgatcca ctgtcttcgc ttcaggggat tcaaaattaa ataatgttac
      781 gtcatatcct tctaaagtta agttatgctc caaccactga taccaatgat ttctactatt
      841 tccatgcata gaatgtacaa taattacatc tgtcatctca ttctctcctt tcaacttact
      901 acttcttttc tatttttaaa aaaatgactg attacctata attgtaaaat aaaaacacct
      961 taattagaaa tgttatatcg caaagtgaca tttctaatta aagtgtattg tcatcatttc
     1021 aatatcattc aaaaacagct aaacctttgt ctctgcttca atttcacaaa aataattccc
     1081 gctgaaagta tctatattta cacattactt ccaccattat ataacttaaa aatgactata
     1141 tttcatcaaa cattatctaa aggcgtcgca cctacaccaa caccatccaa caattaactt
     1201 acaactctgc gattacttct tcagcagcaa ctttaccttg tgtaatacaa tcaggtagtc
     1261 caaccgcttc aaaagatgca ccagttactc taagtcgtgg atatgtttgt ttaatatgtg
     1321 cttgaatctg tctaatttgt tgaatatgac cgacatggta ctgtggcata cttttcggca
     1381 aacgattgac aattgtaaat tcaggatcac ctttaaatgt catcatttga cttaaatctc
     1441 tacgtacaat cgatactaat tcattatctg tatgatcatc aaccacagta tcacctggtt
     1501 tacctacata cgcacgaatc aaaaccttac cttctggtgt agtaaatggc cattttttcg
     1561 atgtccaagt acatgcggta atgtctgtat cactcgttct cgcaatcacg aagccagtac
     1621 catcataagt attttcaatg tctttttcat caaatgccaa tacaacagtt gcaacagtcg
     1681 tactatccat cgttttaaag taatcaaatg ctggatcttg tccgaaccaa ttcaaaaaga
     1741 cttgatgcgg tgttgtcact aataccccat cgaatacatc ttcttgttga ttactgtaaa
     1801 caattttata ttgcttttga gatgtaataa tatcatccac tgacgtattg tagcgtattg
     1861 tcacaccttt atttttcaca tcttgttcta atgcttcaat aaatgagctt aaaccatgct
     1921 taaattgttt gaattgtcct tttggtgcgc caggatataa ttgtctttgt ttcagacgct
     1981 tatttttctc atccttcata ccttttatca gacttccgaa tgcctcttct ttttctttaa
     2041 aattaggaaa cgtactcatc aaacttaatt tatcaatatc ggtaccataa ataccaccca
     2101 ttaaaggctc aattaagttc tcaagtacct cattacctaa tcttgctctg aaaaatgcac
     2161 caacagaaat gtcaccatct tgcatttgta taggcttttt gattaaatct aatcctgctc
     2221 ttaatttacc aagtggcgat attaattttg tagtaacaaa tggtttaata tctgttggaa
     2281 tacccataat tgaaccacct ggaatcggat ataatttatt tttcgcaaaa atatatgatt
     2341 gtccagtcgt atttgtaaca atatcttgtt ctaatccaat atctttcgct aattctgtca
     2401 taatcgtttt tctacctaaa taagattcag gccctagttc aatcatataa ccatctttac
     2461 gatacgattg aatctttccc cccggacgat tcgatgcttc aaagatggtt acatcaatat
     2521 taggatcttg ctgttttaaa aaatatgcac ttgataaacc tgttatcccc gctcctataa
     2581 tagccactga tttagtcaca acgtttcacg cttctttcgt cattaaaata tagacttgat
     2641 ttcatcaaca attgcaccga taaataatgg atgtgtattc ggcatttttg gacgataata
     2701 attcgcacca atatcatcgc aaacaacttt acattcataa tcattgtcat aaagcacctc
     2761 taaatgctca catacaaaac ctactggcgt atatataaag tttttatact gatgtttttc
     2821 atataaatca cgtgttaaat cttgtacatc tggccctaac caaggtgtac ctgtattacc
     2881 ttcagattgc caaccaatcg cgatatgttc aatattagat tgttctttaa ttaaaagcgc
     2941 agtatgttct agttcttgtg gatatggatc attattcttt tcgattaaac cttttggcaa
     3001 actatgtgcc gaaacaacta ataccgtgtc tttatgttcc tcttccggta tttgagctaa
     3061 tgtttcgttg actttattcg tccaatattc aataaattta ggttgttcat aataatgttt
     3121 cacatgtgta agttgaatac catattttgc agcttcttca tcagcacgtt tgtcatatga
     3181 tcctactgaa aatgaagaat aatgtggtgc tagtactacc gtgattgctt cagtaatacc
     3241 atcattgtgc atttgttcaa ccgcatcttc gataaatggt gaaatgtgtt ttaatcctaa
     3301 gtatagttta aattcaacat ctgcatatgc tttatttaat gctgaaacta gtgcatcagc
     3361 ttggtcatct gttgtacctg ctaatggtga taaaccacct ataaattcat atctatcttt
     3421 caaatcttga agttcttctt cagatggacg tttaccatgt ctaatatctg tataatatgg
     3481 ctctatgtca ctttctttat aaggtgtgcc ataagccata actaataacc ccattttttt
     3541 agtcattgat aataccttcc tttaaatgaa ttatctttca tgtgcttcaa tgtaatacta
     3601 tgattatctt tgtgtatatg tgtgtacgaa ttcgcttact ttacgtaacg tctctggttg
     3661 cacttctggg aaaacaccgt gtcctaaatt aaagatgtgt ttaccgttct ccataccttg
     3721 atctaatatt ggtttcaatc tctcttcaat gacattccat ggtgctaata aaattgatgg
     3781 atctaaattc ccttgtaatg ttttagtaac gcctaattgt tgagcctgat taatagacgt
     3841 tctccaatct aggcctaata catcaatcgg taaatcattc cattcattga ttaaatgact
     3901 ggcacctaca ccgaataaaa ttaccggcac atcatgtttt tctttaacct cactgattaa
     3961 tcgaatcata tgtggtttaa tgtaacgtct gtaatcctcg acatttaatg cacctaccca
     4021 tgaatcgaaa atttgaatca attcggcacc tgcttcgact tgagctgtta catatttaac
     4081 agatacatca actaaatgat tcattaaagc aaaccatgtt gcttcatctc tatacatcat
     4141 cgcttttgta aaattgtaat ttttcgatgg tccgccttca atcatatatg acgctaatgt
     4201 aaatggtgcc ccagtaaatc ctattagcgg cacatttaac ttttcttctg ttaaaagttt
     4261 aattgtatct aatacatatg gtacatctcg ttcggggtct atttgagaaa gtttctcaac
     4321 atcttgaatt gttttgatag gattatgaat cactggacca atacccgatt taatttctac
     4381 atcgacacca attggcttta atggtgtcat aatatctttg tataaaattg ctgcatctgt
     4441 atgataatta tcaactggta aatgtgttac ataagcgcac aactccggct gatgtgtaat
     4501 atcgaatagt gaatattttt ctttcaattt tcgatattct ggttgcgaac ggccagcttg
     4561 tcgcataaac caaacaggtg tatgtgatgt ttcttcacct ttgatcattt ttaaaattgt
     4621 attgttttta ttatgcacca taaaggcctc ctaaattaaa atcattctta tctatattat
     4681 catatcgctc attcgttcgt attttcaata aataaatgtc ataaaactga catttaatca
     4741 tagaactatt tattgtaaat ttaaattcta aagtccatta ttttgtatca ttacttctaa
     4801 atatctcgca agattcatta tagtaatttt aatcaattat taatagtggt aatgactagt
     4861 ttatcatcgt ataataaata aaaacataag ggggaccttt catatgaaga aactatatac
     4921 atcttatggc acttatggat ttttacatca aataaaaatc aataacccga cccatcaact
     4981 attccaattt tcagcatcag atacttcagt tatttttgaa gaaactgatg gtgagactgt
     5041 tttaaaatca ccttcaatat atgaagttat taaagaaatt ggtgaattca gtgaacatca
     5101 tttctattgt gcaatcttca ttccttcaac agaagatcat gcatatcaac ttgaaaagaa
     5161 actgattagt gtagacgata atttcagaaa ctttggtggc tttaaaagct atcgtttgtt
     5221 aagacctgct aaaggtacaa catataaaat ttatttcgga tttgctgatc gacatgcata
     5281 cgaagacttt aagcaatctg atgcctttaa tgaccatttt tcaaaagacg cattaagtca
     5341 ttactttggt tcaagcggac aacattcaag ttattttgaa agatatctat acccaataaa
     5401 agaatagact cgaagaaaac ttccattggt tatgctgtta acgtatagat gctaatgtaa
     5461 tctgaacgcc gtatcatttg gcgttcaaca ttacatgcac ctttacaaca tacatgccaa
     5521 tggaagtttt ttagtctcgt aataatgttt cctgatattt caacttttta ataatacttc
     5581 taatcgttaa taaacctaca atatagaaaa tgagtacaac atagaataac gtcatatgtt
     5641 ttataataaa tgtcactgca aacacagtac aaataacaaa cattaatcta tataaaaact
     5701 gttcataccc tttgattacc ttctcttcag gtacaggcca cacttgaggc cataagccat
     5761 atgcttgttg tgaataaaat tgtgccattt gcaacaatat aatatacaca aaaagacttc
     5821 caataacccc tgtcactaat ggatatgata accaaaccat aagtaaaact gcaataatta
     5881 ctaacctaaa gataatatta aatgcgtctc tccctcttat aaagcttcta ataaataaga
     5941 ataaatacat cgcattagag ttaaatttac taccctttgg aactggtaaa agtatatcta
     6001 gataacttct tctgactgca gattctttca aatgttttac atcggtgaac atattaacaa
     6061 atttataata attcatatga tgtcgatgtt cgatagcaat cattttctcc caaggataca
     6121 aaaagcctgg tttatatttt ttaactaaaa attctattaa cacaggcaaa gcaaccatca
     6181 caaatacgat gtaccatttt ggagctaata gtaagtaata tgttagagca aagatgataa
     6241 atgatattaa attaacttgc catgttttaa gtcccgattg ataccattgc catcttaagc
     6301 gtaaaccaac atatggaaaa attaatgcac tgaatccaaa acaaatataa aatgccacat
     6361 tatgttgatt aatattgtaa aacaacggga acattacaat aacaataatg agttggatta
     6421 atatgcgcgc aaagtaacta tataaaatcg catggcgcat aaattgagac atgtgttttt
     6481 caaatggtaa taaaaagatt ttatccgctt cttttaggag tggtcgcatt ggaaaaatgg
     6541 atgtcaacgc aacaatcact gctgctatta atgcaaaatt gatattcgtt ggaatatgtt
     6601 ttaaccattc accatatcca aaaataaatg cacccagcaa aataagtaaa aagaccatga
     6661 aatgaccatt aaatataaac ttattataat aatttttctc tttacgaagg gcatgtaatc
     6721 ttttattaaa taatgtggtc gcttggttat gcatgtacat ctccaccttg cgtcacatga
     6781 atatatatat cgtctaatgt ttgattatgt aagccagttt gttgtctcaa tgcttctaaa
     6841 tctccaaatg caacgacttc accttcgtct agtatgataa aacgatcaca ataacgttca
     6901 gctgttgcta aaatatgtgt actcattaga acgattctac cttcgttttt cttttcaacc
     6961 attaaatcta acatggattg aattcctaat ggatctagtc caaggaatgg ttcgtctata
     7021 atatacaatt cgggattaac gataaacgca caaataatca tgactttttg tttcatcccc
     7081 ttagaaaaat gactcggaaa aactttcaat tcattttcta aacggaatgt ctttaataat
     7141 ggcattgctc gattcatcgc ttcatcacga tcaatatcat atgccattgc tgtcatctct
     7201 atatgttcct ctaatgtgag ttcttcataa ataaccggtg attccggaat ataagataac
     7261 tttcttctat atgcctctat gtcatcatta atgttgatat ctgaaattga tagagatcct
     7321 tccataggtg taagcaatcc tagcatatgt ttaatcgttg tactcttacc agcgccatta
     7381 aggccaataa gtccaacgat ttcgcctttg tttaattcaa aatttatatc tttaattaca
     7441 gggcgttttc catatccacc tgtaagctgt tctactttaa ctgtcataag gcacctccat
     7501 gacttatatt gtaccaaaaa ttataaaatg ctcatattaa atacacatgt cctaatatcg
     7561 aatttttagc gacaatgtta taatgaatgg taatactagt tgaaaaggag tgtagtcatc
     7621 atgtcagaaa caattttcgg caaaatttta actggagaaa ttcctagctt taaagtatat
     7681 gaagacgatt atgtctatgc ctttttagat atatcacaag ttactaaagg acatacgtta
     7741 ttaattccta aaaaagcttc tgctaatatc tttgaaactg atgaagaaac aatgaaacat
     7801 atcggtgcag cattacctaa agtagcaaat gctattaagc gtgcatttaa tcctgatggt
     7861 ttaaacatta ttcaaaataa tggtgagttt gcagatcaat ctgtatttca tattcatttc
     7921 cacttaattc ctcgatacga aaatgatatt gatggatttg gttataagtg ggaaacacat
     7981 gaagacattt tagataacga tgcaaaacaa caaattgctg aacaaattca agcacaattt
     8041 taaatgtatg cttaatctaa gctcgaacgg gtataatatg attaatatta taacaattgc
     8101 gtttgaagtg ataacatcaa ggttagcaat tttaaacaaa atgagttatc aagataacag
     8161 atgttaaaag tgaggagaat ataaatgaaa gcatcacgca ttctattcgg tatcggtgtt
     8221 ggcgtagcag ctggttttgt agttgcactt caaggacgag acgacaaaag tgtcaagaac
     8281 aacacgatcg atcgtactgc ccctactggt tcaaaatcag aactacaacg tgaatttgaa
     8341 acgattaaac aaagttttaa tgacatttta aactatggtg ttcaaattaa aaacgaaagt
     8401 gcggaatttg gtagttcaat tggtggtgaa attaagtcat tacttggaaa cttcaaatct
     8461 gacattaatc ctaatattga acgtttacag tcacacatcg aaaatttaca aaatcgtggc
     8521 gaggatattg gaaacgaaat ttctaagtag cacgttacgt tctcgatcac aactattttt
     8581 attagtaaca gcatatttat ttttttaaat taaatgccaa ataaacgaga tgacattaga
     8641 aattagatat ttcttgtcat ctctttttta taactcaaat gaacttatgt ttacaaatta
     8701 caggaataca tcgtttgtag tgattttcgc ttaaatcata tttatgaatt gattgaaaac
     8761 attgcttagg attcattgtg ttatccttgc actttgatta cgctttactt atatcattat
     8821 cgacaaacaa catacttata ttttcattga gccgaacctt atatacacat tacatatacc
     8881 ttacttgcac aaattattaa tctggtattt attataatta catatcacta tatttttagc
     8941 atttgtataa cttagttggt caaaagatgc ttttgcatat gccctgccat atccattttt
     9001 tatattattc aagttttcaa atactcatgt cacacgcgcc tttttcataa gtgatgcttt
     9061 attagcaaga agatgtgttc gcagaaattt gttctgcatt ctacttctac gctagtcaat
     9121 cagccaattt taccaatctc cactttcgcg tttcaaatca aacaatacgt gtctcccctt
     9181 tcttcttata taacaattct tctaacatga tatgttacta ttgaattact gaacctgagt
     9241 tagttataat ctaacttata ttgaaaagag atgaggcgta agatatgttt ttatgtaaaa
     9301 gacaaattga tatcaatgca cgatttggtt tgcctagaat tgcatttatg agtgcagttg
     9361 caaccatcat tatgttttta gttagttatg aagtaatgta ttttttatct aatacgccat
     9421 tatcagatag acattttctc atctttttat tacttgtatt tatgacgtat ccattacata
     9481 aaagtataca tttattattt ttcttaccat atagaaaatc gtttaaagtt cataagttaa
     9541 ctaaaagaaa atggcttata ttctataata cctacgtcaa tcaacctgta cacaaatttt
     9601 atttttgcat taacttaata ttgccgttaa ttatcttatc tgcaatgttc gtttatctaa
     9661 caatttcatt cccgcaatat ggacattatt ttatgttctt attggcattg aatttcggta
     9721 tttccattac agatttatta tatttaaaaa taattatatt ttctaatt
//
LOCUS       DAPDIM010000081         9599 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000081 DAPDIM010000000
VERSION     DAPDIM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9599
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.081"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..180
                     /locus_tag="RFE25_002425"
     CDS             <1..180
                     /locus_tag="RFE25_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HDU2817460.1"
                     /translation="KLQDILDKEKQVKDEKAKSEEEKAKAKDEKLKQQEENEKKQKEQ
                     AQKDKEKRQEAERKK"
     gene            202..4641
                     /gene="essC"
                     /locus_tag="RFE25_002426"
     CDS             202..4641
                     /gene="essC"
                     /locus_tag="RFE25_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HDU2817461.1"
                     /translation="MHKLIIKYNKQLKMLNLRDGKTYTISEDERADITLKSLGEVIHL
                     EQNNQGTWQANHTSINKVLVRKGDLDDITLQLYTEADYASFAYPSIQDTMTIGPNAYD
                     DMVIQSLMNAIIIKDFQSIQESQYVRIVHDKNTDVYINYELQEQLTNKAYIGDHIYVE
                     GIWLEVQADGLNVLSQNTVASSLIRLTQEMPHAQADDYNTYHRSPRIIHREPTDDIKI
                     ERPPQPIQKNNTVIWRSIIPPLVMIALTVVIFLVRPIGIYILMMIGMSTVTIVFGITT
                     YFSEKKKYNKDVEKREKDYKAYLDNKSKEINKAIKAQRFSLNYHYPTVAEIKDIVETK
                     APRIYEKTSHHHDFLHYKLGIANVEKSFKLDYQEEEFNQRRDELFDDAKELYEFYTDV
                     EQAPLINDLNHGPIAYIGARHLILEELEKMLIQLSTFHSYHDLEFLFVTREDEVETLK
                     WARWLPHMTLRGQNIRGFVYNQRTRDQILTSIYSMIKERIQAVRERSRSNEQIIFTPQ
                     LVFVITDMSLIIDHVILEYVNQDLSEYGISLIFVEDVIESLPEHVDTIIDIKSRTEGE
                     LITKEKELVQLKFTPENIDNVDKEYIARRLANLIHVEHLKNAIPDSITFLEMYNVKEV
                     DQLDVVNRWRQNETYKTMAVPLGVRGKDDILSLNLHEKAHGPHGLVAGTTGSGKSEII
                     QSYILSLAINFHPHEVAFLLIDYKGGGMANLFKDLVHLVGTITNLDGDEAMRALTSIK
                     AELRKRQRLFGEHDVNHINQYHKLFKEGVATEPMPHLFIISDEFAELKSEQPDFMKEL
                     VSTARIGRSLGIHLILATQKPSGVVDDQIWSNSKFKLALKVQDRQDSNEILKTPDAAD
                     ITLPGRAYLQVGNNEIYELFQSAWSGATYDIEGDKLEVEDKTIYMINDYGQLQAINKD
                     LSGLEDEETKENQTELEAVIDHIESITTRLEIEEVKRPWLPPLPENVYQEDLVETDFR
                     KLWSDDAKEVELTLGLKDVPEEQYQGPMVLQLKKAGHIALIGSPGYGRTTFLHNIIFD
                     VARHHRPDQAHMYLFDFGTNGLMPVTDIPHVADYFTVDQEDKIAKAIRIFNDEIDRRK
                     KILSQYRVTSISEYRKLTGETIPYVFILIDNFDAVKDSPFQEVFENMMIKMTREGLAL
                     DMQVTLTASRANAMKTPMYINMKTRIAMFLYDKSEVSNVVGQQKFAVKDVVGRALLSS
                     DDNVSFHIGQPFKHDETKSYNDQINDEVSAMTEFYKGETPNDIPMMPDEIKYEDYRES
                     LSLPDIVANGALPIGLDYEGVTLQKIKLTEPAMISSENPREIAHIAEIMMKEIDILNE
                     KYAICIADSSGEFKAYRHQVANFAEEREDIKAIHQLMIEDLKQREMDGPFEKDSLYII
                     NDFKTYIDCTYIPEDDVKKLITKGPELGLNILFVGIHKELIDAYDKQIDVARKMINQF
                     SIGIRISDQQFFKFRFIQREPVIKENEAYMVANQAYQKIRWFK"
     gene            4671..5063
                     /gene="esaC"
                     /locus_tag="RFE25_002427"
     CDS             4671..5063
                     /gene="esaC"
                     /locus_tag="RFE25_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion substrate EsaC"
                     /protein_id="HDU2817462.1"
                     /translation="MNFNDIETMVKSKFKDIKKHAEEIAHEIEVRSGYLRKAEQYKRL
                     EFNLSIALDDVESTAKDVQTAKSSANKDSVSVKGKAPNTLYIEKRNLMKQKLEMLGED
                     IDKNKESLQKAKGIAGEKASEYFNKAMN"
     gene            5079..5393
                     /gene="esxB"
                     /locus_tag="RFE25_002428"
     CDS             5079..5393
                     /gene="esxB"
                     /locus_tag="RFE25_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WXG100 family type VII secretion effector EsxB"
                     /protein_id="HDU2817463.1"
                     /translation="MGGYKGIKADGGKVNQAKQLAAKIAKDIEACQKQTQQLAEYIEG
                     SDWEGQFANKVKDVLLIMAKFQEELVQPMADHQKAIDNLSQNLAKYDTLSIKQGLDRV
                     NP"
     gene            5393..6067
                     /locus_tag="RFE25_002429"
     CDS             5393..6067
                     /locus_tag="RFE25_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5081 family protein"
                     /protein_id="HDU2817464.1"
                     /translation="MKDVKRIDYFSYEELTILGGSKLPLVNFELFDPSNFEEAKVALI
                     EKELVTENDKLTDAGFKVATLVREYISAIVNIRINDMYFAPFSYEKDEYILLSRFKNN
                     GFQIRIINKDIAWWSIVQSYPLLMRQEKSNDWDFKQIDDEILENLNNESIDTIGRVLE
                     IEIYNHQGDPQQSLYNIYEQNDLLLIRYPLKDKVLNVHIGVINTFIRELFGFDTDENH
                     INKAEE"
     gene            6067..6384
                     /locus_tag="RFE25_002430"
     CDS             6067..6384
                     /locus_tag="RFE25_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817465.1"
                     /translation="MTLSGKISVKAETIAHVVKELESISQKYDEIAQNFGKIAQLNYY
                     SSEKAAHSMENGYSSAATVISGLKGPLSTLGGGVMNSAQKFFEADEHWGTEFAKLYYN
                     IEG"
     gene            6394..8238
                     /locus_tag="RFE25_002431"
     CDS             6394..8238
                     /locus_tag="RFE25_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease YeeF family protein"
                     /protein_id="HDU2817466.1"
                     /translation="MTKDIEYLTADYDNEKSSIQSVIDAIEGQDFLDVDTTMDDAVSD
                     VSSLDEDGAISLTSSVVGPQGSKLMGYYQNELYDYASQLDSKMKEIIDTPFIEDIDKA
                     FKGITNVKLENILIKNGGGHGRDTYGASGKIAKGDAKKSDSDVYSIDEILKSDQEFVK
                     VIDQHYKEMKKEDKKLSKSDFEKMMTQGASCDYMTVAEAEEIEEQKKKEEAIEIAALA
                     GMVVLSCINPVAGAVAIGAYSAYSAANAATGKNIVTGRKLSKEERIMEGLSLIPLPGM
                     GFLKGAGKSLMKLGFKGGEKFAVKTGLQKTMQQAVSRISPKMGMMKNSVLNQSRNFAQ
                     NTHVGQMLSNMRGQATHTVQQSRNWIGQQAQNVKRIVNNGLDKEIAHPFKQQLAPAGM
                     GGIKFAETTTLRNMGQNMKRTVTPQNHVTHGPKDSMVRSEGKHSVSSHEINLSKYVES
                     PNYTKVKYGEQYARLRPKKLKANIEYTTPTGHIYRTDHKGRIKEVYVDNLSLKDGGRN
                     NHAQRTVGGEDRLPDDDGGHLIARMFGGSKDIDNLVAQSKYINRSFKENGDWYKLEKL
                     WEKAIKSGKSIENIKIEVKYKGNSQRPTIFKVEYEINGKRNIRRILNK"
     gene            8249..8740
                     /locus_tag="RFE25_002432"
     CDS             8249..8740
                     /locus_tag="RFE25_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01741 family protein"
                     /protein_id="HDU2817467.1"
                     /translation="MTFEEKLSKIYNEIANEISNMIPVEWEKVYTMAYIDDGGGEVFF
                     NYTKPGSDDLNYYTDIPKEYNISVQVFDDLWMDLYDLFEELRDLFKEEDLEPWTSCEF
                     DFTREGKLKVSFDYIDWINTEFDQLGRENYYMYKKFGVIPEMEYEMEEVKQIEQYIKE
                     QEE"
     gene            8943..>9599
                     /locus_tag="RFE25_002433"
     CDS             8943..>9599
                     /locus_tag="RFE25_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5079 family protein"
                     /protein_id="HDU2817468.1"
                     /translation="MTTKENIDTLRKPGAQALSLISLFLILFSCLTFFFGLDYERFPN
                     YLKITTIIELIIIVISLLQWIRFIDFEKESARKYKKIYARFLVIINVLTTITVVFALC
                     NLYYFAAVQNHYDLFNYWLMGTISIIISYLLLVIGGMFTLLKLPKVTKRWGGKTKTHF
                     GLLLTALSSFIYIEKIIEYILIPNVVESKFIIIVSMLVIAGAQFVAFQFIMQYSRFYI
                     F"
BASE COUNT         3672 a         1284 c         1895 g         2748 t
ORIGIN      
        1 aaattgcaag atattttaga caaagaaaaa caagttaaag atgaaaaagc gaaatctgaa
       61 gaagagaaag caaaagcgaa agatgagaaa ttaaagcaac aagaagagaa cgaaaagaaa
      121 caaaaagaac aagcacaaaa agataaagaa aaacgccaag aagctgaaag aaaaaaatag
      181 tataggactg aggcaaagac aatgcataaa ttgattataa aatataacaa acaattgaag
      241 atgctcaatt tgcgagatgg taagacatat actattagcg aagacgagcg tgcagatatt
      301 acgttgaaat cgttaggcga agtcattcat ttagaacaaa ataatcaagg tacttggcaa
      361 gcgaatcata cttctattaa taaggtgctt gttagaaaag gtgaccttga tgacattaca
      421 ttacagcttt atacagaagc tgattatgca tcatttgcgt atccttcaat tcaagatacg
      481 atgacaattg ggccaaatgc gtatgatgat atggttattc aaagcttgat gaatgccatc
      541 attattaaag attttcaatc aatacaagaa tcacaatacg tacgcattgt gcacgataaa
      601 aatacagatg tgtatattaa ctatgaacta caagagcaat taacaaacaa agcttacatt
      661 ggtgatcata tttatgttga agggatatgg ctcgaagtac aagctgatgg tttaaatgta
      721 ttgagtcaga atacagtggc atcgtcatta attcgcttaa cacaagagat gccacatgca
      781 caggcagatg attacaatac gtaccatcgt tcgccaagga ttattcaccg tgaaccgacc
      841 gatgatatta agattgaaag accgccacag ccaatacaga agaacaatac agtgatatgg
      901 cgttccatta taccgccatt agtaatgatt gctttaactg ttgtcatctt tttagtgaga
      961 ccaattggta tttatatttt aatgatgatt ggtatgagta cagtaacgat agtatttggt
     1021 attacaacgt atttctctga aaagaaaaag tataacaaag atgttgaaaa acgagagaaa
     1081 gattacaaag cttatttgga taataaatct aaagaaatta ataaagcgat taaagcacaa
     1141 cgttttagtt tgaattacca ttatccaacg gttgctgaaa ttaaagatat cgttgaaacg
     1201 aaagcaccaa gaatatatga aaaaacatcg catcatcacg atttcttaca ttataagtta
     1261 ggtattgcga atgtagaaaa gtcattcaaa ttagattacc aagaagaaga atttaaccaa
     1321 cgtcgtgatg aactattcga cgatgctaaa gaattgtatg aattttacac agatgtagaa
     1381 caagcaccat taatcaatga tttaaatcat ggaccaattg catatattgg tgcacgacat
     1441 ctcattttag aagaattgga gaaaatgcta atccaattgt caacgttcca tagttatcat
     1501 gatttagagt ttctatttgt gacacgtgaa gatgaagttg aaacattgaa atgggcacgt
     1561 tggttgccac atatgacatt gagaggtcaa aacattagag ggtttgttta caatcaacga
     1621 acacgtgacc aaattttaac gtcaatttat agcatgatta aagaacgtat ccaagctgtg
     1681 cgtgaacgca gcagaagtaa tgagcaaatt attttcacac cgcaattagt gtttgtcatt
     1741 acagatatgt cattaattat tgatcatgtc attttagaat atgtaaacca agatttatca
     1801 gaatatggta tttcattaat ctttgttgaa gatgtgattg aaagtttgcc agagcatgta
     1861 gataccatta ttgatatcaa gtctcgtact gaaggcgaac tgattacgaa agaaaaagaa
     1921 ttagttcaat tgaaatttac acctgaaaat attgataacg ttgataaaga atatatcgcg
     1981 agacgtttgg cgaatttgat acacgtcgaa catttgaaaa atgcaattcc tgatagtatt
     2041 acatttttag agatgtataa cgtgaaagaa gtagatcagc ttgatgtggt taatcgatgg
     2101 agacaaaacg aaacatacaa aacgatggca gtacctttag gtgtaagagg taaagatgat
     2161 attttatcat tgaacttaca tgaaaaagca cacgggccac atggtttagt tgctggtacc
     2221 actggttcag ggaaatctga gattatccaa tcatacattt tatctttagc tattaatttt
     2281 catccacatg aagttgcgtt cctattgatt gactataaag gtgggggtat ggcgaactta
     2341 tttaaagatt tagtccattt agttggtacg attacaaact tagatggcga tgaagcgatg
     2401 cgtgccttaa catcaatcaa agccgaattg agaaaacgtc aacgtttatt cggagagcat
     2461 gatgttaacc atattaatca ataccataag ttatttaaag aaggtgttgc aacagaacca
     2521 atgccacatt tattcattat ttccgatgag tttgccgaat taaaatcaga acaacctgat
     2581 tttatgaaag aacttgtatc aacggcacgt attggacgtt cgttaggtat tcatttaata
     2641 cttgcgacac aaaaaccatc gggtgttgtt gatgaccaaa tttggtctaa ctctaaattt
     2701 aaattggcat taaaagtaca agatagacaa gacagtaatg aaattttaaa aacaccagat
     2761 gcagcagaca ttacattacc aggtcgtgcg tatttacaag ttggtaataa tgaaatttat
     2821 gaattattcc aatctgcatg gagtggtgca acatatgaca tcgaaggcga taaattagaa
     2881 gttgaagata agacgattta catgattaat gactatggtc aacttcaagc aatcaacaaa
     2941 gacttgagtg gacttgaaga tgaagaaacg aaagaaaacc aaaccgagtt agaagcggtt
     3001 atcgatcata tcgaatctat tacaacacga ttagaaattg aagaagttaa gcgtccatgg
     3061 ttaccaccat taccagaaaa tgtatatcaa gaagatttag tagaaacaga tttcagaaaa
     3121 ttatggtcag atgatgcaaa agaagtggaa ttaacattag gacttaaaga cgtaccagaa
     3181 gaacaatatc aaggaccgat ggtattgcaa ttgaaaaaag ctgggcacat cgcgttaatc
     3241 ggaagtccag gatatggtag aacaacgttc ttacacaaca ttattttcga tgttgcaaga
     3301 caccatcgtc ctgatcaagc acacatgtac ttgttcgatt tcggtaccaa tggtttgatg
     3361 ccagtcacag atataccaca tgttgctgat tattttacag tagatcaaga agacaagatt
     3421 gctaaggcga tacgtatatt taatgatgaa atcgatcgtc gtaagaagat tttaagtcag
     3481 tatcgtgtta ctagtatttc tgaatatcga aaattaactg gtgaaacaat tccgtatgtc
     3541 tttattctta ttgataactt tgacgcagta aaagattcac ctttccaaga agtttttgaa
     3601 aatatgatga ttaaaatgac acgtgaaggg ctagcattag acatgcaagt aaccttaact
     3661 gcttcaagag ctaacgcaat gaaaacgcca atgtacatta atatgaaaac gcgtatcgcc
     3721 atgtttttat atgataaatc agaggtgtcg aacgtagtag ggcaacaaaa atttgcggtt
     3781 aaagatgtag tgggtcgagc attgttaagt agtgatgaca atgtatcatt ccatattggc
     3841 caaccattta aacatgatga gactaaatca tataatgatc aaattaatga tgaagtatcg
     3901 gcgatgacag aattttataa aggtgaaaca ccaaatgata ttcctatgat gccagatgaa
     3961 attaaatatg aagattacag agaatcatta agcttaccag atatagttgc caatggtgct
     4021 ttaccaattg gattagatta tgaaggtgtt acactacaaa aaattaaatt aactgaacca
     4081 gcaatgattt catcagaaaa tccgagagaa attgcgcata ttgccgaaat tatgatgaaa
     4141 gaaattgaca tattaaatga aaaatatgcg atttgtatcg cagactcaag tggagagttt
     4201 aaagcttata ggcatcaagt ggctaacttt gccgaagaaa gagaagacat taaagcgatt
     4261 catcaactaa tgattgaaga cttaaaacaa agagaaatgg acggtccatt tgaaaaagat
     4321 tcactttaca ttatcaatga ttttaaaaca tatattgatt gcacgtatat cccggaagat
     4381 gatgttaaaa agcttattac aaaaggacca gaacttggct tgaacatttt atttgtcggc
     4441 attcataaag aattaataga tgcttatgat aaacagattg atgttgcacg taaaatgatt
     4501 aaccaattta gtataggtat tcgtatttca gaccaacaat tctttaaatt tagatttatt
     4561 caacgagaac ctgttattaa agaaaacgaa gcgtatatgg tcgcgaatca agcttatcaa
     4621 aagattagat ggtttaaata gtaatgaatt aaataggagg gaggtatgtt atgaatttta
     4681 atgatattga aacaatggtc aagtcgaaat ttaaagatat taaaaagcat gctgaagaga
     4741 ttgcgcatga aattgaagtt cgttctggat atttaagaaa agctgaacaa tataagcgat
     4801 tagaatttaa tttaagtatt gcactagatg atgttgaaag cacagcaaag gacgtacaaa
     4861 ctgcaaaatc tagtgctaat aaagacagtg tatctgttaa aggaaaagcg cccaatacgt
     4921 tatatatcga aaaaagaaat ttgatgaaac aaaagcttga aatgttgggt gaagatatcg
     4981 ataaaaataa agaatccctc caaaaagcta agggaattgc tggcgaaaag gcaagtgaat
     5041 attttaataa agcaatgaat taatattgag gtgaagatat gggtggatat aaagggatta
     5101 aagcagatgg tggcaaggtg aatcaagcga aacaattagc ggcaaaaata gctaaagata
     5161 ttgaagcatg tcaaaagcaa acgcaacagc tcgctgagta tatcgaaggt agtgattggg
     5221 aaggacagtt cgccaataag gtgaaagatg tgttacttat tatggcaaag tttcaagaag
     5281 aattagtaca accgatggct gaccatcaaa aagcaattga taacttaagt caaaatctag
     5341 cgaaatacga tacattatca attaagcaag gacttgatag ggtgaaccca tgatgaaaga
     5401 tgttaagcga atagattatt tttcttacga agaattaaca attttaggtg gtagtaaatt
     5461 gcctctcgta aattttgaat tgtttgatcc atcaaatttt gaagaagcta aagtggcttt
     5521 aattgaaaaa gaattagtaa cagagaatga caagttaact gatgcaggtt ttaaagtggc
     5581 tacattagta agagagtata ttagcgcaat tgtaaatatt cgaattaatg atatgtattt
     5641 tgcaccattt agctatgaaa aagatgaata tattttgtta agccggttta aaaataatgg
     5701 gtttcaaata cgaattatca ataaagacat tgcatggtgg tcgattgtac aatcatatcc
     5761 tttattgatg agacaagaaa aatccaatga ttgggacttt aaacaaattg acgatgaaat
     5821 attggagaac ttaaataatg aaagtatcga tacgattggg cgtgttttag aaattgaaat
     5881 ctacaatcat caaggtgacc ctcaacaaag tttatataac atttatgaac aaaatgattt
     5941 gttactcatt cgatacccat taaaagataa agtgctgaat gttcatattg gtgtcattaa
     6001 tacatttata cgagaattat ttggattcga tactgatgaa aatcatatta ataaagcaga
     6061 ggagtaatga cgttgagtgg aaaaattagt gttaaagctg aaacgattgc acatgttgta
     6121 aaagaattgg aaagcattag tcaaaagtat gatgaaatag ctcaaaactt tggaaaaata
     6181 gcgcaattaa attactacag tagtgaaaaa gctgcacatt ctatggaaaa tggctatagt
     6241 agtgctgcaa cagtcattag tggtctcaaa ggtccattga gtacactcgg tggtggcgtc
     6301 atgaattcag cacaaaagtt ctttgaagca gatgaacatt ggggtacgga atttgccaag
     6361 ctttactata atattgaggg ataggtgcat gacatgacaa aagatattga atatctaaca
     6421 gctgattatg acaatgaaaa gtcatctatc caaagtgtaa tagatgcaat agagggtcaa
     6481 gacttcttag atgtagatac aacaatggat gatgcggtaa gcgatgtcag ttctttagac
     6541 gaagatggcg caatatcatt aacaagtagt gtagtaggtc cacaaggatc taaattaatg
     6601 gggtattatc aaaatgagct atatgattat gcatctcaat tagattcgaa aatgaaagaa
     6661 attattgaca cgccatttat agaagatata gataaagcat tcaaaggtat aacgaatgtt
     6721 aaattggaaa atatattaat aaaaaatggc ggtggtcatg gtagagatac ctatggggct
     6781 tctgggaaaa ttgcaaaggg agatgccaag aaaagtgaca gcgatgttta tagcatcgat
     6841 gaaatattaa aatcggatca agaatttgta aaagtaattg atcagcatta caaagaaatg
     6901 aaaaaagaag ataagaaact atctaagagt gattttgaaa aaatgatgac tcaaggtgct
     6961 tcttgtgatt acatgacagt agctgaagcg gaagagatag aagagcaaaa gaaaaaagaa
     7021 gaagctatag agattgcagc actagctggt atggtagttt tatcttgtat taatcctgtt
     7081 gctggagcag tagctattgg tgcttattcc gcttattcag cagcaaatgc agccacagga
     7141 aaaaatattg taactggaag aaagctatct aaagaagaac gaatcatgga aggactttcg
     7201 cttattccat tgccaggtat gggcttcctc aaaggtgctg ggaaaagttt aatgaaatta
     7261 ggcttcaaag gcggagaaaa atttgcagtt aaaacaggat tgcaaaagac aatgcaacaa
     7321 gcagttagtc gtatttcacc taaaatggga atgatgaaaa acagtgtgtt gaatcaatct
     7381 cgtaactttg ctcaaaatac tcatgttgga caaatgctga gtaacatgcg tggtcaagca
     7441 actcatactg ttcaacaaag tagaaattgg attggacaac aagcacaaaa tgtcaaacga
     7501 atagtgaata atggacttga taaagaaata gcacatccat ttaaacaaca acttgcacca
     7561 gcgggaatgg gtggtataaa atttgctgaa acaactactt tgagaaacat gggtcaaaac
     7621 atgaaacgta ctgttacacc acaaaatcac gtgacacatg gtccgaaaga tagtatggtg
     7681 agaagtgaag gtaaacatag tgtaagtagc catgaaataa atttatcaaa atatgttgaa
     7741 tcaccaaact acaccaaggt caaatatgga gagcaatatg caagacttag acctaagaaa
     7801 ctaaaagcaa atatagaata tacaacacca actggtcaca tatatcggac tgatcataaa
     7861 gggcgcataa aagaagttta tgtagacaat ctttctctaa aagatggcgg tcgtaataac
     7921 catgcacaaa gaactgtggg aggagaggat agattaccag acgatgatgg aggtcactta
     7981 atcgccagaa tgtttggtgg gtcaaaagac atagataacc ttgtagcaca aagtaaatat
     8041 atcaaccgtt catttaagga aaatggtgat tggtacaagt tggaaaaact atgggaaaag
     8101 gcaatcaagt ctggaaaatc aatagaaaat attaaaatag aagttaaata taaaggtaat
     8161 agtcaaaggc cgactatatt taaagttgaa tatgaaatta atggtaaaag aaatattaga
     8221 agaatattaa ataagtagag gtgccaacat gacatttgaa gagaagctta gcaaaatata
     8281 caatgaaatt gcgaatgaga ttagcaatat gataccggta gagtgggaaa aagtatatac
     8341 aatggcttat atagatgatg gaggagggga ggtattcttt aattatacta agccaggtag
     8401 tgatgacttg aattattaca ccgatatacc taaggagtat aacatttctg tgcaagtatt
     8461 tgatgattta tggatggatt tatatgattt gtttgaggag ttaagagatt tatttaaaga
     8521 agaagattta gaaccatgga catcatgtga atttgacttt acaagagagg gtaaattgaa
     8581 agtatcattt gattatatag attggataaa tacagagttt gatcaattgg gccgtgaaaa
     8641 ttattatatg tacaaaaaat ttggggttat accagaaatg gaatatgaaa tggaggaggt
     8701 taaacaaatc gagcaatata ttaaagagca agaagaatag acaatcttaa tgtgagacta
     8761 aacaataaag ctttgtttag tcttttttgg cggttaagta aaaagcaata gataccgtaa
     8821 agttgatgct cgtcaaataa taatataaag atagttttat gctttgtata gataaaaacc
     8881 taagtactta taactttaaa tacgtaatat gctatttaaa agataatgta taggagacag
     8941 atatgactac taaagaaaat attgatactc ttcgaaagcc aggtgcacaa gccttaagtt
     9001 taatatcatt gtttttgata cttttttcat gtctaacttt cttttttggt ttagattatg
     9061 aaaggtttcc aaactattta aagataacga caattataga attaataatt attgtaatta
     9121 gtttacttca atggattagg tttatagatt tcgaaaaaga aagtgcacgg aaatataaaa
     9181 aaatatatgc tcgattttta gttattataa atgtgttaac tactatcact gtagtatttg
     9241 cactgtgtaa cctttattat tttgcagctg tacaaaacca ttatgattta ttcaattatt
     9301 ggttaatggg tacgatttca atcataatta gctatttatt attagtaatt ggcggaatgt
     9361 ttacgttgtt aaaattacct aaagtaacaa aacgctgggg tggtaaaact aaaacacatt
     9421 tcggtttatt attaactgcg ttgagctcat ttatatatat tgaaaaaatt atcgaatata
     9481 tattgattcc taatgtcgta gaatccaagt ttataattat tgtgagcatg ttggttatcg
     9541 ctggagcaca atttgtggca tttcaattta ttatgcaata cagtagattc tatattttt
//
LOCUS       DAPDIM010000082         9455 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000082 DAPDIM010000000
VERSION     DAPDIM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9455
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.082"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            160..795
                     /locus_tag="RFE25_002434"
     CDS             160..795
                     /locus_tag="RFE25_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDU2817469.1"
                     /translation="MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQI
                     DSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTY
                     NFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQ
                     KVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE"
     gene            1099..2178
                     /locus_tag="RFE25_002435"
     CDS             1099..2178
                     /locus_tag="RFE25_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE family protein"
                     /protein_id="HDU2817470.1"
                     /translation="MWMIFSGLIVGGLLGFVMQRTRFCLTGGFRDMYVQKNNKMFYAL
                     LIAITIQSIGLLILTATDILQIPAHSFPILGTIIGSFIFGIGIVLAGGCATGTWYRAG
                     EGLIGSWIALVLYAVTAAITKTGILKPVMDKINQPTNVNSDMSQTTGIPFWGLVVILT
                     IITIFLVVRTLNNKKVRVAVPKLKQRYTGIRYYLFEKRYHPFIAAIVIGLIALLAWPM
                     SASTGRNDGLGITTPSANLVHFLITGETKFIDWGVFLVLGIFIGSYIAARGSREFKWR
                     LPDKITIRNSAIGGICMGFGASVAGGCSIGNGLVETATMTWQGWIALASMIVGVWTMS
                     HFIFVRPMKKVQQQSAKVKQQTQIV"
     gene            2238..2462
                     /locus_tag="RFE25_002436"
     CDS             2238..2462
                     /locus_tag="RFE25_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HDU2817471.1"
                     /translation="MIHELGTVGMVCPFPLIEAQKKMATLQSGDELKIDFDCTQATEA
                     IPNWAAENGYPITNYEQIDNASWTITIQKV"
     gene            2670..3920
                     /locus_tag="RFE25_002437"
     CDS             2670..3920
                     /locus_tag="RFE25_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDU2817472.1"
                     /translation="MNLNDTIFMFLCTLLVWLMTPGLSLFYGGLVQSKNALNTVMQSM
                     AAIVLVTFVWITVGFTISFGNGNLWFGNWEYTFLNHVGFATQEDISPHIPFALFMLFQ
                     MMFCTIAISILSGSIAEKMKFIPYLLFVVIWTALVYSPVAHWVWGGGWINKLGVLDFA
                     GGTVVHITSGVSGLVLAIMIGKGNKHSESTPHNLIITLIGGIFVWIGWYGFNVGSAFT
                     FDNIAMLAFTNTVISASAGAIGWLILEYIFKKTTSLLGLLLGALAGLVVITPAAGYVT
                     YLSATIMALIGGICCYIVINYIKVKLKYHDALDAFGIHGVGGIIGAVLTAVFQSKKAN
                     PDIENGFIYTGDIHIILVQILCVTAVVIFSIVMTFIIAKVIKLITPLSVTEQETNIGL
                     DKIVHGEHAYFEGELNRFNKHIRY"
     gene            4103..5053
                     /locus_tag="RFE25_002438"
     CDS             4103..5053
                     /locus_tag="RFE25_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDU2817473.1"
                     /translation="MKNISDIAKLAGVSKSTVSRFLNNGSVSKKTSEKLTRIIAEHDY
                     QPNQFAQSLRARQTHLIGAIIPRMNSYAVDETIKGLAKQCQKYESQLILNYTGLNIEA
                     EIQALETLARSKVDGIVLMATDITERHIEVINKMNVPIVIVGQQHEQLHSIVHDDYKA
                     GQIIGEWIGQQGYQQVEVFSVSEKDIAVGIHRKRGLLDQLAKYQIKPNIHETNFTYVE
                     AQKDVANVLENVEQVDAVVGATDTIALAAYKYYSDKNDVMKPHQIYGFGGDPMTQLVS
                     PSIKTIHYNYFEAGQCAMEEIQQMLKKQDMPYSVTVDVNI"
     gene            5202..6686
                     /locus_tag="RFE25_002439"
     CDS             5202..6686
                     /locus_tag="RFE25_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HDU2817474.1"
                     /translation="MTEWTREERYQRIEDVDTEYFKTLKQQVDQSKFRQQFHIQPETG
                     LLNDPNGLIFYKGKYYVSHQWFPLGAVHGLKYWYNYTSDDLINFKPEGPILNPDTKYD
                     SHGVYSGSAFEYNGHLYYMYTGNHRDNHWQRHASQMIARLKEDGSVEKFPKPVISQQP
                     EGYTSHFRDPKVFKYGEKYYAIIGAQNNDQQGRLLLYNTEDIINWHYLGEINTELDDF
                     GYMWECPDYFNLDNQDVILICPQGIEPKGNQFKNIYQSGYILGKFDIEKLTYEHENFV
                     ELDNGFDFYAPQTFLDEKGRRVLIGWMGLPEIEYPTDNEGWAHCLTIPRVLNVENGQL
                     KQRPYPALEKLRHNKETALGYANKFTRKLHPYEGKQYELIIDILDNDATEVYFELRTS
                     KTSSTLIAYNKRENKITLDRSDSGLLPTNVEGTTRSTILDTPLKQLQIFVDTSSIEIF
                     CNDGERVLTSRIFPTEDALGIKTSTESGQVYLQFTKYDLKDEHK"
     gene            6683..7642
                     /locus_tag="RFE25_002440"
     CDS             6683..7642
                     /locus_tag="RFE25_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDU2817475.1"
                     /translation="MRRLFSIGEALIDFIPNVTNANLKDVQTFTKQIGGAPCNVACTV
                     QKLGQQAYMITQLGNDAFGDSIIETISSIGVDVSKVYRTNEANTALAFVSLTEAGERD
                     FSFYRKPSADMLFEPSFVNDIDVNENDVVHFCSVDLVDSPMRDAHYQLITKTLNANGT
                     VVFDPNVRLPLWDNAEDLRQTIHTFLPLAHIVKVSDEELEFITGIHDENEAIQSLFTG
                     NVTVVIYTKGADGAAVYLKNGINHYHSGYKVKPVDTTGAGDAFIGAVISRILATDVLN
                     LTQLFENEGEEILAFSNRVAAIVTTKYGAINSLPTLQEVEQAF"
     gene            complement(7830..7939)
                     /locus_tag="RFE25_002441"
                     /pseudo
     CDS             complement(7830..7939)
                     /locus_tag="RFE25_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500747.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8011..8727)
                     /locus_tag="RFE25_002442"
     CDS             complement(8011..8727)
                     /locus_tag="RFE25_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDU2817476.1"
                     /translation="MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVL
                     EQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKV
                     AAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
                     FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKER
                     IVYFKNKEHCYASVRNVKKI"
     gene            complement(8746..>9455)
                     /locus_tag="RFE25_002443"
     CDS             complement(8746..>9455)
                     /locus_tag="RFE25_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDU2817477.1"
                     /translation="VILIMSLFTLKEMKYKRNQEEIETYYEYTLKIEAINNEMRKFRH
                     DYVNILTTLSEYIREDDMIGLRAYFNKNIVPMKDNLQMNAIKLNGIENLKVREIKGLI
                     TAKILRAQEMNIPISIEIPDEVSSINLNMIDLSRSIGIILDNAIEASTEIDDPIIRVA
                     FIESENSVTFIVMNKCADDIPRIHELFQESFSTKGEGRGSGLSTLKEIADNADNVLLD
                     TIIENGFFIQKVEIINN"
BASE COUNT         3262 a         1303 c         1756 g         3134 t
ORIGIN      
        1 gtcttgaaac taagatattt atttttaaaa ttcaataatg tataatattt aggtattcat
       61 tgtaatcaat tatttgtttt ttaataatct aacaattacg ctctaactcg tttgaataca
      121 tagatataat tcattcaaac acgaaggagg aaatagcgaa tgagtgacca agttaaaatt
      181 cctcgagcaa ctttaaaacg tttgccgtta tattatagat ttgtcagttc attaaaatct
      241 aaaggtatag atcgtgtaaa ttcaaaagcg attagcgatg cgttacaaat tgactcggca
      301 acaattcgtc gtgacttttc atattttggc gaattaggta aaaaagggta cggatataat
      361 atagatagtt tattggattt ctttaaatct gaactaagcg agagtgacat gatcaaaatc
      421 gcaattgtcg gagttgggaa cctagggaaa gctttgctca catataactt ttcaatacat
      481 gacgatatga cgattacaga agcgtttgac gtaaaagaag atgttattgg ccagaaaata
      541 gggaacgtta ttgtaaaaga taacgatgaa ttaataacaa cattgaagaa ggaagaaata
      601 gatgttgtga ttctaactac accagaaaga gttgcacaga aagttgcaga tgaactcgtc
      661 caagctggtg tgaaaggtat tttaaacttc actcctggta gaattaatac gccttcagat
      721 gtgcaagtac atcaaattga cttaggtata gaattacagt cattattatt ctttatgaaa
      781 aattacagtg aataaatgtg atgttagctt tgaatgatta accttgttat atctttaatt
      841 aattatagaa cagtctggga ctaagtatgt ctcaggcttt ttctgttatg tttgaaaatg
      901 aaaggaaaaa ctgttgtgtt gataaatata gtataggtta ataaattaac acgtagagat
      961 ataatgatga atcgtaatta atcgccttcc ttatatgaat ataatataaa tatcaaaaat
     1021 attgtgtata aggttgaaaa caagaaaatc atcacctata atacatacta aacttatcgg
     1081 aaatgagggg ttaggattat gtggatgatt tttagtggct taattgtcgg gggactctta
     1141 ggttttgtca tgcaaagaac aagattttgt ttaacaggtg gctttcgaga tatgtatgtg
     1201 caaaagaata ataagatgtt ctatgcatta ttaatcgcta ttactattca aagtatagga
     1261 ttattgattt tgacggcaac agatatttta caaattcctg cacatagttt tccaatattg
     1321 ggaacaatta taggttcttt tatttttgga attggaatag tattggctgg agggtgtgca
     1381 acaggtactt ggtatcgcgc tggtgaaggg ctaattggta gttggattgc attagtatta
     1441 tatgctgtta ctgcagcaat cactaaaaca gggattttaa agccagtaat ggataaaatt
     1501 aatcaaccaa cgaatgtaaa tagtgatatg tctcaaacaa ctggcattcc gttttgggga
     1561 ttagtcgtta tattaactat aatcaccatt tttctagttg taagaacact caataataag
     1621 aaagttcgag ttgctgttcc aaaactaaag caacgttata caggtattag atattacctt
     1681 ttcgaaaaac gataccatcc atttattgca gcaattgtaa ttggacttat cgcactctta
     1741 gcttggccaa tgagtgcatc aactggaaga aatgacggtt taggtataac aacgccttca
     1801 gcaaatttag tacacttttt gattacaggt gaaactaaat ttattgattg gggtgtcttt
     1861 ttagttctag gaattttcat tggttcatat attgcagcta gaggatcaag agaatttaaa
     1921 tggcgattgc cagacaagat tacaatacga aacagtgcca ttggtggcat atgtatggga
     1981 tttggtgcgt cagttgctgg tggttgttct atcggtaacg gtttggttga aacggcaacg
     2041 atgacttggc aaggatggat tgcgctagca tcgatgatag ttggtgtatg gacaatgagt
     2101 cattttatct ttgttcgtcc aatgaaaaaa gtacaacaac aatccgcaaa ggttaaacag
     2161 caaacgcaaa tagtatagaa gattattatg caaatgatgt tgatcaaata aaagtgattg
     2221 gaaaaggaga aataattatg atacacgaat taggtacagt aggaatggta tgtccatttc
     2281 cgttaattga agcgcaaaag aaaatggcaa cattgcaatc tggagatgaa ttaaaaattg
     2341 attttgattg cacgcaagcg acggaagcca ttccaaattg ggctgcagaa aatggttatc
     2401 ctataacaaa ctatgaacaa attgataatg cttcatggac aattacaatt caaaaagttt
     2461 aacgttatca ttttaacaat aaaatagata ttagattcta tggctacttc cgctaattta
     2521 aaagtgagta agtagtcttt tttgttttag ttcatgaaat catttttata tagtgtggca
     2581 tattttattt caaaagatgt aataaaactt aacgcatttt tgctttttat aaattgtcag
     2641 attattatga aaacaaggga gtggtaagta tgaatcttaa cgatacgata tttatgtttt
     2701 tgtgtacatt attagtttgg ttaatgacac caggattaag tttattttat ggtgggttag
     2761 ttcaatctaa aaatgcgctt aatactgtca tgcaaagtat ggcagcaatt gtgcttgtta
     2821 catttgtatg gataacagtt ggttttacaa ttagttttgg gaatgggaat ttatggttcg
     2881 gaaattggga atatactttt cttaatcatg taggttttgc gactcaagaa gatattagcc
     2941 cacatattcc tttcgctttg tttatgttat ttcaaatgat gttttgtacg attgcaattt
     3001 ctattttatc tggttcaatc gctgagaaaa tgaagtttat tccttattta ttattcgtag
     3061 taatatggac tgctcttgta tacagtccag tagcacattg ggtttggggc ggcggttgga
     3121 ttaataaact cggtgtatta gatttcgctg gaggtacggt tgttcatatt acatcaggtg
     3181 tttctggttt agtattagct attatgattg gaaaaggaaa caaacattct gaatcaacac
     3241 cacataatct tatcattacg ttgattggcg gtatattcgt gtggattggt tggtatggat
     3301 ttaatgtagg tagtgctttt acatttgata atattgcgat gcttgcattt acaaatactg
     3361 tcatttcagc cagtgcaggt gctataggtt ggttaatttt agaatatatt tttaaaaaga
     3421 cgacaagttt acttggactt ttactcggtg cattagcagg attagttgtt attactcctg
     3481 cagcaggata tgtaacatat cttagtgcaa caataatggc tttaatagga ggtatctgtt
     3541 gttatattgt cattaattac atcaaggtaa aactaaaata tcatgatgca ttagatgcat
     3601 ttggtattca tggtgttggt ggtattattg gtgctgtttt aacagcagtt ttccaaagta
     3661 aaaaagccaa tcctgacatt gagaatggct ttatttatac tggtgacata catattatac
     3721 ttgtacaaat attatgtgta acagcagttg taatttttag tatcgtcatg acgtttatta
     3781 ttgcgaaagt aattaaatta attacaccat tatctgttac ggaacaagaa acgaatatag
     3841 gattagacaa gattgttcac ggtgaacatg cttactttga aggtgagcta aatagattca
     3901 ataaacatat tcgatattag aatatattta catagaatat tcattgtcct gacatttaac
     3961 taaaggttga tgttgggaca ttttgttata caaaagtttt attttgaaat ctttttatga
     4021 aagaagcaga aatattattt aaagcggtta cacatatgct aaaataaggc taagtgtcac
     4081 aaataatgat aggtgaataa gtatgaaaaa tatatctgat attgccaaat tggcaggcgt
     4141 ttcaaaaagc acagtatcta gatttttaaa taatggatct gtcagtaaaa aaacaagtga
     4201 aaaattaaca agaattatag cagaacatga ctatcaaccg aatcaatttg ctcaaagttt
     4261 aagagcgaga caaacacacc ttattggtgc cattatacct agaatgaatt catatgcagt
     4321 agatgaaaca atcaaaggat tggcaaaaca atgccaaaaa tatgaatcac aattaatttt
     4381 aaattacaca ggtttaaata tcgaagcaga aatacaagcg cttgaaacat tagcacgcag
     4441 taaagtagat ggtattgttt taatggctac agacataaca gagagacata ttgaagtcat
     4501 taataaaatg aatgtaccaa tcgttattgt tggtcaacaa catgaacaac ttcatagtat
     4561 tgtgcatgat gattataaag caggtcaaat tataggcgaa tggattggtc aacagggata
     4621 tcaacaagtt gaagtgttta gtgtaagtga aaaagatatt gcagttggta tacatagaaa
     4681 acgtggttta cttgaccagt tagctaaata ccaaattaaa cctaatatac atgaaacaaa
     4741 ttttacttat gtggaagcac aaaaagatgt tgcaaatgtt ttggaaaatg tggagcaagt
     4801 agatgcggtt gttggagcaa ctgatacgat tgcattagct gcctataaat attattctga
     4861 taaaaatgat gttatgaaac cacatcaaat atatggtttt ggtggtgacc caatgacaca
     4921 attagtgtct ccatcgataa aaacaattca ttataattat tttgaagctg gccaatgcgc
     4981 gatggaagag atacaacaga tgcttaaaaa gcaagatatg ccatatagcg tcacagtaga
     5041 tgttaatatt tagacgctgt attttttaaa acaaatgtgg aaccgatacc atataactat
     5101 aaatggatag gttaaaagtt aaagaacgta ggtaaaattt gctataatag aatataaatt
     5161 gttaacagca taaattataa aaggaggact gggtaaatat tatgaccgaa tggactagag
     5221 aagaacgtta tcaacgaatc gaggacgttg atactgagta ttttaaaaca ttaaaacaac
     5281 aagttgatca atcaaaattt cgtcaacaat ttcatataca accagaaaca ggtttattaa
     5341 atgatcccaa cggacttatt ttttataaag ggaagtatta tgtttcacat caatggttcc
     5401 cattaggcgc agtacatggc ttaaagtatt ggtataacta cacgagtgat gacttaataa
     5461 actttaaacc tgaagggcca atattaaatc cagatactaa atatgacagc catggtgttt
     5521 atagcggtag cgcttttgaa tataacgggc atttatatta tatgtacaca ggaaatcatc
     5581 gagataatca ttggcaacga catgcgagtc agatgatcgc acgattgaaa gaagacggtt
     5641 cagttgaaaa gtttccaaag ccagtaatta gccagcaacc agaaggatat acaagtcatt
     5701 ttagagatcc taaagttttt aaatatggtg agaaatatta tgcaatcatt ggcgcacaaa
     5761 ataatgatca gcaaggtcga ttattacttt ataatactga agatataatt aattggcatt
     5821 atttaggtga aataaataca gagttagatg attttggata tatgtgggaa tgcccagatt
     5881 actttaattt agataatcaa gatgtcatac ttatttgtcc acaaggtatt gaaccaaaag
     5941 gcaatcagtt caaaaatatt tatcaaagtg gttatatact tggaaagttt gatattgaaa
     6001 agttaacata tgaacatgaa aattttgtcg agcttgataa tggctttgat ttctatgcac
     6061 ctcaaacatt tttagatgaa aaaggccgac gagtactaat tggatggatg gggttaccgg
     6121 aaatcgaata tcctactgat aatgaaggat gggcccattg cttaacaatt cctcgtgtat
     6181 taaatgtaga aaatggtcaa cttaagcaac gtccatatcc agcgttggaa aaattacgtc
     6241 acaataaaga gacagcatta ggctacgcaa ataaatttac tcgaaaatta catccgtatg
     6301 aaggtaaaca gtatgaatta atcatagata ttttggataa tgatgctacc gaagtgtact
     6361 ttgaattacg tacatctaag acttcttcaa cattaattgc ttataacaag cgtgaaaata
     6421 aaataacatt agatcgcagc gacagtggtt tattgccgac aaatgttgaa ggtacgacgc
     6481 gtagtacgat attagacacg ccattaaagc aattacaaat ttttgttgat acatctagta
     6541 tagaaatttt ctgtaatgat ggggaacgtg ttttgacatc tcgaattttc ccgacagaag
     6601 acgcactagg tattaaaaca tcaacagaat cagggcaagt atatttacaa tttactaaat
     6661 atgatttaaa ggatgaacat aaatgagacg tctattttca ataggagaag cgttaattga
     6721 ttttattcca aatgttacaa atgcgaattt aaaagatgtt caaacattta cgaagcaaat
     6781 tggtggcgcg ccatgcaatg tagcttgtac agttcaaaag ttaggacaac aagcgtatat
     6841 gattacacaa ttaggtaatg atgcatttgg agatagcatt attgaaacga tatcaagtat
     6901 tggtgtagat gtatcaaaag tgtatcgcac gaatgaagca aacactgcgt tagcttttgt
     6961 gagtttgact gaagcgggcg agcgagattt ttctttttat cgtaagccct ctgctgatat
     7021 gttatttgaa ccaagttttg tgaatgatat tgatgtgaat gaaaatgatg tagtacattt
     7081 ttgttctgtt gatttggtcg atagtccgat gagagatgca cattatcaat tgattaccaa
     7141 aacattaaat gcaaatggta ctgtcgtatt tgatcctaat gtaagattgc cattatggga
     7201 taacgctgaa gatttaagac aaactattca tacctttttg ccattggcgc atattgtaaa
     7261 agtttcagat gaagaattag aatttattac aggtattcat gatgaaaatg aagccattca
     7321 atcattattt acaggtaatg ttactgtagt catttatacg aagggagcag atggtgctgc
     7381 cgtatatttg aaaaatggta ttaatcatta tcatagtggc tataaggtaa aacctgttga
     7441 tacaactggg gcaggggatg cttttattgg tgcagttatt agcaggattt tagcaaccga
     7501 tgtgttaaat ttaactcagt tatttgaaaa tgaaggtgag gaaattttag cgtttagcaa
     7561 tcgcgttgct gcaatagtga caacgaagta tggtgccatt aatagtttgc caacattaca
     7621 agaggttgaa caagcatttt aaataattca tttataaaac agtgtaggaa acaagttgaa
     7681 tcttgtgcta cactgttttt taaaacaaaa taagattcac ggggtaggaa attgtagcat
     7741 tttatttatg gaaactgtca atttcaaatt tagtatattt tgttaaaaat tgcgccatag
     7801 gattgtagag tgaaatagaa attgataaat tatgtagtaa taggaatagg tatacaaaga
     7861 aacgttacat cattttttaa ttcacgcgtc atatttaatt ttgttattaa acaattaaaa
     7921 agccagctat acagtgcatt tgctagttat cttgttaaaa tccaacaaga tttacaattg
     7981 aatacgccgt taactgactt tattatctta ttatattttt ttaacgtttc tcaccgatgc
     8041 atagcagtgt tctttatttt taaaatagac aattcgctct ttcgaatcta tagattcaat
     8101 attatggcga ttgacgacaa agctattatg acatctaaag aaacgatcat ctaattgact
     8161 cagttctttt aaattaccat aaaattcaat ttgacggtta tctaaatggg caatgagtct
     8221 gtgagatttt gttgatgatt caaaaaacat aatatcatca tattgaacat acactgaatt
     8281 actgccacgt tttaattcaa tcgtttcaac gctattatct ttagacaaca attgtaagcg
     8341 tgtatgtgca gtttctaaac aatctataat tcgagttctt aattctgctg gatcatcttt
     8401 aaaaataaaa tccatcgctg caactttgta gacaaatgtt aaataggtaa gttcactgtg
     8461 actcgtaacg aaaataatgt taccaactgg gtcatgctta cgaatttcac tgcctaattt
     8521 gataccatta atatcagttg aaagttgaat atctaaaaag taacagccta tgtcattcat
     8581 atttttagct tgctcaagca cctcataagg attatcagtt gcgagggcaa tttccatagg
     8641 cttttcttct atcattatat aatttttaat aatggtaacc atgttttctc tttgttttgg
     8701 atcgtcttcg caaatgaaaa ttttcataca ttcacatcct tatggctagt tgttaataat
     8761 ttcaactttt tgaataaaga aaccattttc gataattgta tctaataaga cattgtctgc
     8821 attatcagca atttctttta aagttgatag acctgaacca cgaccttcac ctttagtaga
     8881 aaaactttct tggaacaatt catgaatgcg tggtatatca tcagcgcatt tattcataac
     8941 aataaacgtt actgaatttt cactttcaat aaatgcaacg cgaatgatag ggtcatcaat
     9001 ttcagttgat gcctcaattg cattatcaag aataatacca atactgcgac ttaaatcgat
     9061 catattcaag ttaatgctac ttacttcatc gggtatttcg atactaattg gaatattcat
     9121 ttcttgtgca cgtaaaattt tcgcagtaat taagcctttt atctcacgta ctttaagatt
     9181 ttcgatacca tttaatttaa tagcattcat ctgcaaatta tctttcatag gtacaatatt
     9241 tttattgaaa taagcgcgta gaccaatcat gtcatcttcg cgaatgtatt ctgaaagtgt
     9301 cgttaagata ttgacataat catgacggaa cttgcgcatt tcattattaa ttgcttcaat
     9361 ctttaatgtg tattcgtaat aggtctcaat ttcttcttga tttcgtttgt atttcatctc
     9421 tttaagggtg aaaagcgaca ttataagtat tacaa
//
LOCUS       DAPDIM010000083         9415 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000083 DAPDIM010000000
VERSION     DAPDIM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9415
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.083"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            26..643
                     /locus_tag="RFE25_002444"
     CDS             26..643
                     /locus_tag="RFE25_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDU2817478.1"
                     /translation="MYSVISKILNFILVKMSKSLYVIGKDNIPKDSKYVVTCTHESYN
                     EVIMLGMALYPNQIHYMAKKELFKNKWIGKFLTSLNAFPVDRENPGPSTLKRPINLLK
                     DNKTVGIFPTGSRTSQEGAPLKRGASTIAMLSKSPILPVAYVGPTKIHGLLTGQAYIN
                     IGKPIDINDLPKDLKRNERIDYITKEIETRTAKLQQELHEIVKSL"
     gene            771..2237
                     /locus_tag="RFE25_002445"
     CDS             771..2237
                     /locus_tag="RFE25_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIBC"
                     /protein_id="HDU2817479.1"
                     /translation="MYKFFQNLGRSLMLPVAILPAAAIIAGIGNTLNALHATPKIAMF
                     FTTVGTTILEQLGILFAIGVAIGMAKKNDGAVALAATLGYFLVTVVLSPMKLAPLLGM
                     KASEINSAFEKMNNGNVFVGIVIGLIAAYAYNKFSETELPLALSFFSGKRLVPIMTAF
                     YCTFLVVILLFLWPLLYSWIVKFGESIVGLGSFGAFIYGVANRLLIPTGLHHALNSVF
                     WFDTIGINDIGKFQSGKDAIKGITGRYQAGFFPIMMFGIPAAALAMYHTAKTTQKKQV
                     YGWFLASSVAAFFVGVTEPIEFAFMFVAPILYVVHALLTGLSLFIAATFHWTAGFSFS
                     AGLIDYVLSLINPVSNHPLMLLVQGVVFFILYYVIFRVVIQVFNLNTIGRGENELVDP
                     TVVKDNIAPGENDIKQSKYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQ
                     QKIKNAGAVGVTVNGKHSTQVIVGTHVQQVADEIEKHL"
     gene            2344..3474
                     /locus_tag="RFE25_002446"
     CDS             2344..3474
                     /locus_tag="RFE25_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDU2817480.1"
                     /translation="MKKILFDVDGIFLSEERCFDVSALTVYELLMDKCYLGLHSHIDW
                     ETLTDNDIQDIRNRIFQKDKILNKLKSLGLNSNWDMLFIVFSIHLIDILKKLSHDEIE
                     AFMYQDEPVELKLQNISTNLADCFNLNEQLPLQFLDNVKVGKNNIYAALEEFATTELH
                     VSDATLFSLKGALWTLAQEVYQEWYLGSKLYEDVEKKIARTTFKTGYIYQEIILRPVD
                     EVKVLLNDLKGAGFELGIATGRPYTETVVPFENLGLLPYFEADFIATASDVLEAENMY
                     PQARPLGKPNPFSYIAALYGNNRDKYESYINKQDNIVNKDDVFIVGDSLADLLSAQKI
                     GATFIGTLTGLKGKDAAGELEAHHADYVINHLGELRGVLDNL"
     gene            complement(3435..3530)
                     /locus_tag="RFE25_002447"
     CDS             complement(3435..3530)
                     /locus_tag="RFE25_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817481.1"
                     /translation="MKPLVQSFTSSYAVKQQSNYKLSSTPLSSPK"
     gene            complement(3624..5228)
                     /locus_tag="RFE25_002448"
     CDS             complement(3624..5228)
                     /locus_tag="RFE25_002448"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDU2817482.1"
                     /translation="MKQFNVLVADPISKDGIKALLDHEQFNVDIQTGLSEEALIKIIP
                     SYHALIVRSQTTVTENIINAADSLKVIARAGVGVDNININAATLKGILVINAPDGNTI
                     SATEHSLAMLLSMARNIPQAHQSLTNKEWNRNAFKGTELYHKTLGVIGAGRIGLGVAK
                     RAQSFGMKILAFDPYLTDEKAKSLSITKATVDEIAQHSDFVTLHTPLTPKTKGLINAD
                     FFAKAKPSLQIINVARGGIIDEKALIKALDEGQISRAAIDVFEHEPATDSPLVAHDKI
                     IVTPHLGASTVEAQEKVAISVSNEIIEILIDGTVTHAVNAPKMDLSNIDDTVKSFINL
                     SQTVGELAIQLMYNAPSSIKITYGGDLASIDSSLLTRTIITHILKDDLGPEVNIINAL
                     MLLNQQQVTLNIENNKAETGFSNYLEVELSNDSDSVKVGASVFTGFGPRIVRINNFSV
                     DLKPNQYQIVSYHNDTPGMVGKTGALLGKYNINIASMTLGRTEAGGDALMILSVDQPV
                     SNNIIDELKQVGEYNQIFTTELTVQS"
     gene            complement(5215..6372)
                     /locus_tag="RFE25_002449"
     CDS             complement(5215..6372)
                     /locus_tag="RFE25_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDU2817483.1"
                     /translation="MYYHQPLLLTPGPTPVPDAIMREIQAPMVGHRSKDFEDIAQQAF
                     QGLKPIFGSQNDVLILTSSGTSVLEASMLNIVNPEDHFVVIVSGAFGNRFKQIAQTYY
                     KNVHIYDVTWGEAVDVKDFINYLSTLDVEVKAVFSQYCETSTTVLHPIHELGNAINQF
                     NSNIYFVVDGVSCIGAVDVDINKDKIDVLVSGSQKAIMLPPGLAFVAYSHRAKERFKE
                     VTTPKFYLDLNKYISSQADNSTPFTPNVSLFRGVNAYVETVKAEGFNHVIARHYAIRN
                     ALRSALKALDLTLLVNDKDASPTVTAFKPNTNEVKIIKDELKNRFKITIAGGQGHLKG
                     QILRIGHMGKISPFDILSVVSALEIILTEHRKVNYIGKGISKYMEVIHEAI"
     gene            complement(6487..6933)
                     /locus_tag="RFE25_002450"
     CDS             complement(6487..6933)
                     /locus_tag="RFE25_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDU2817484.1"
                     /translation="MHQHDFKVQTSWQGGRNNVGNVQGDILSENISIPASLGGVGIGT
                     NPDEMLVSAASSCYIISLAATLERAKFTDISIEQQSIGTACLNNGKFSMSKIVHHPHI
                     EIPSDQIAQLEKRLPKLITIADNNCMISNAVRNNVDIKIYPIIQAK"
     gene            7013..7756
                     /locus_tag="RFE25_002451"
     CDS             7013..7756
                     /locus_tag="RFE25_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDU2817485.1"
                     /translation="MTLNKLKDELQIVSHRGLPSDFPENTMVGYREVMGLNVAMLEID
                     VHLTKDQHFVVIHDETIDRTSDGKGRIADYTLSQLKSFDFGSYKDVAFKGERIPTLDE
                     VLSLCLKYDKKLLIELKSPNLYPEIECKLLAFLEEKKVDATQVVIQSFDIECIEKLNT
                     LGSIYELGVLCSKRNYWYKKPNFSRIAQIASYVNPNYALVARKFVDKAHHHQLQVMPY
                     TVNKLKTGEKLRQMGVDGLITDNPKLFIK"
     gene            complement(7972..8574)
                     /gene="rpsD"
                     /locus_tag="RFE25_002452"
     CDS             complement(7972..8574)
                     /gene="rpsD"
                     /locus_tag="RFE25_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019165370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDU2817486.1"
                     /translation="MARFRGSNWKKSRRLGISLSGTGKELEKRPYAPGQHGPNQRKKL
                     SEYGLQLREKQKLRYLYGMTERQFRNTFDIAGKKFGVHGENFMILLASRLDAVVYSLG
                     LARTRRQARQLVNHGHILVDGKRVDIPSYSVKPGQTISVREKSQKLNIIVESVEINNF
                     VPEYLNFDADSLTGTFVRLPERSELPAEINEQLIVEYYSR"
     gene            complement(8818..9282)
                     /locus_tag="RFE25_002453"
     CDS             complement(8818..9282)
                     /locus_tag="RFE25_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HDU2817487.1"
                     /translation="MTTINPTNYTLLKKQAASLIEDEHHMIAILSNMSALLNDNLNQI
                     NWVGFYLLEQNELILGPFQGHPACVHIPIGKGVCGTAVSERRTQVVADVHQFEGHIAC
                     DANSKSEIVVPIFKDDKIIGVLDIDAPITDRFDDNDKEHLEAIVKIIEKQLA"
BASE COUNT         3066 a         1427 c         1694 g         3228 t
ORIGIN      
        1 acaaataagt taagtaggtg gcacaatgta ttcagtgatt agtaagattt tgaatttcat
       61 tttagttaaa atgtcaaaat cattatacgt aatcggtaaa gataatattc ctaaggatag
      121 taaatatgtc gtaacttgta cgcatgaaag ttataacgaa gttattatgc taggtatggc
      181 attatatcct aatcaaattc attatatggc taaaaaagaa ttattcaaaa ataaatggat
      241 tggtaaattt ttaacgtctt taaatgcatt tcctgtagat cgtgaaaatc caggacctag
      301 tactttaaaa cgcccaatca atttgttgaa agataataag acagttggta tcttcccaac
      361 aggttctcgc acatcgcaag aaggtgcacc attgaaacgt ggtgcttcaa caattgcaat
      421 gttaagtaag tcaccaatat tacctgttgc ttatgttggt cctactaaga ttcatggtct
      481 tttaacagga caagcataca taaatattgg taaaccaatc gatattaacg atttacctaa
      541 agatttaaaa cgaaacgagc gtatcgatta cattacaaaa gagattgaaa cacgaacagc
      601 aaagttacaa caagaattgc atgaaattgt aaaaagttta taaaataact tgaggtagaa
      661 atatagctgg ttagtatgcc taggtgacta taacggagta tcgaagtagt tattctagtt
      721 acattagtaa tctttatatt tctaccttat tttaagaagg atgacattca atgtataaat
      781 ttttccaaaa tttagggcgt tcgttaatgt taccagttgc cattttaccg gctgcagcaa
      841 ttattgccgg aattggtaat acgttaaatg cacttcatgc gacgccgaaa atcgcaatgt
      901 tctttactac ggtaggtact acgattttag agcaattagg tattttattt gcaattggtg
      961 tagctatagg aatggcaaag aaaaatgatg gtgcagtcgc gcttgcagct acgttaggat
     1021 attttttagt tacagttgta ttatcaccaa tgaaattagc gcctttatta ggaatgaaag
     1081 cttcggaaat aaattcagct tttgaaaaga tgaataatgg caatgtcttt gttggtattg
     1141 taataggttt aatagcagcc tatgcataca ataagtttag tgaaacagaa ttaccattag
     1201 cattatcatt ttttagtggt aaacgtctag ttccaattat gactgcattt tactgtacat
     1261 ttttagttgt catattgtta ttcttatggc cactacttta ttcatggatt gtaaaatttg
     1321 gtgaatctat agtcggttta ggatcgtttg gagctttcat atatggtgtt gccaatagat
     1381 tattaattcc tacaggatta catcatgcac tgaatagtgt gttctggttt gatacgattg
     1441 gtattaatga tattggtaaa ttccaaagtg gcaaagatgc tataaaaggt attacaggac
     1501 gctatcaagc gggattcttc ccaatcatga tgttcggtat tccagcggct gcgttagcaa
     1561 tgtatcatac agctaaaacg actcagaaaa aacaagttta cggttggttc ctagcgagtt
     1621 cagttgcagc atttttcgtt ggtgttacag agccgattga gtttgcattt atgtttgttg
     1681 cgccaatctt atatgttgtt catgcgttat taacaggatt atctttattt atcgcagcta
     1741 cattccattg gacagctgga ttttcattta gtgcaggttt gatagattat gtgttatcac
     1801 taattaatcc agtatcaaat catccattga tgttgcttgt tcaaggtgtt gtatttttca
     1861 tcttatacta tgtgattttc cgtgtagtaa tccaagtatt taacttgaat acgattggta
     1921 gaggtgaaaa tgaattagtt gatccaacag ttgtaaaaga taatattgct cctggtgaaa
     1981 atgatattaa acaaagtaaa tatcatcaac atgctataca aatattagaa ggtttaggcg
     2041 gtcaagagaa tattgttaat ttaaccaatt gtgcaacaag gttgcgtcta gagttaaaag
     2101 acacatctat tattgatcaa cagaagatta aaaacgccgg tgcagttggt gttactgtta
     2161 atggcaaaca ttcaactcaa gttattgtcg gtacacacgt acagcaggtt gctgatgaaa
     2221 ttgaaaaaca tttataaaat ttaaacagct aaagcgcaaa tctaacttca atagggtttg
     2281 cgcttttttt agtcaaatag tagaatgatt tatatctgaa ttttcagaaa tggagtgggg
     2341 attgtgaaga aaattttatt tgatgttgat ggcatttttt taagtgaaga acgttgtttc
     2401 gatgtctctg cattaacggt atatgaatta ttaatggata agtgttattt aggtcttcat
     2461 tcacatatag attgggaaac tttgactgat aacgatatac aagacattag gaatcgaatt
     2521 tttcaaaaag ataagatttt aaacaaatta aaatcgctag ggctgaattc aaattgggat
     2581 atgttattta tcgtttttag tattcattta attgatattt tgaaaaagtt atcacatgat
     2641 gaaattgagg cattcatgta tcaagatgag cctgtcgaat tgaagttgca aaatataagc
     2701 acaaacttag cagactgttt taatttaaat gaacaactac ctttacaatt tttggataat
     2761 gtaaaagttg gtaaaaataa tatttatgct gctttggaag agtttgcaac aacagagtta
     2821 catgtttcgg atgctacttt atttagtttg aagggtgcat tatggacgtt agcgcaagaa
     2881 gtttatcaag aatggtattt aggatcgaag ttgtatgaag atgttgaaaa gaaaatagca
     2941 cgaactactt ttaagacagg ttatatttat caagaaatta ttttgagacc agtagatgaa
     3001 gttaaggtac ttctgaatga tttaaaaggt gctggtttcg aattaggtat tgcaacaggt
     3061 cgtccttata ctgagactgt tgtgccattt gaaaatttag gattgttacc atattttgaa
     3121 gctgatttta ttgcaacagc aagtgatgtt ttagaagcag agaatatgta tccgcaagca
     3181 cgaccattag gaaagccgaa tccttttagt tatatcgcag ctttatatgg taataatcgc
     3241 gataaatatg aatcttatat caataagcaa gataacattg taaataaaga tgacgtattt
     3301 atagtaggcg attcgttagc tgacttatta agtgctcaaa aaataggtgc aacgtttatt
     3361 ggaacattaa caggtttaaa aggtaaggat gctgcaggtg agttagaagc gcatcatgcc
     3421 gactatgtta ttaatcattt aggtgaactt agaggtgtac tagataattt gtaatttgat
     3481 tgttgtttga cagcataact tgaagtgaat gattgaacca aaggtttcat attgagttac
     3541 aatgaaatta ataatgaaaa aatgccaaga agcaatggaa gtaatccaat gtcttcttgg
     3601 cattttgaat ttacataaat tgtttatgac tgtaccgtca attcagttgt gaaaatttga
     3661 ttgtattcac caacttgttt aagttcatca attatattgt ttgaaacagg ttgatcaacg
     3721 gataaaatca ttagcgcatc tccgcccgct tcagttctac ctaaagtcat agatgcaatg
     3781 ttgatattgt atttacctaa caatgcgcca gtttttccta ccatacctgg agtatcatta
     3841 tgatatgaca caatttgata ttgatttggc tttaagtcta cagaaaaatt attaattcta
     3901 acaattcttg gaccgaaacc tgtaaagaca gaagcgccaa ctttaacgga atcgctatcg
     3961 tttgatagtt ctacctctaa gtagttacta aaacctgtct ctgctttatt attttcaata
     4021 tttaatgtca cttgttgttg atttaacaac attagagcat tgataatatt gacttcagga
     4081 ccaagatcat cttttaaaat atgagtaata attgtacgtg ttaataaact actatcaata
     4141 gaggctaagt cgccaccgta cgtaatttta atagagcttg gtgcattgta cattaattga
     4201 atagctaatt caccaactgt ttggcttaaa ttgatgaatg attttacagt atcatctata
     4261 ttgcttaagt ccattttagg tgcattcact gcatgcgtta cagtaccatc aattaaaatt
     4321 tcgatgattt catttgaaac agaaattgcc actttttctt gagcttcgac tgttgatgca
     4381 cccaaatgag gtgtaacaat aattttatca tgtgcaacaa gaggcgaatc agttgcaggt
     4441 tcatgttcaa acacatcgat agctgcccga ctaatttgtc cttcgtctaa tgcttttatt
     4501 agcgcctttt catcaataat accaccacgt gccacattga ttatttgcaa actaggtttt
     4561 gctttggcaa aaaagtcagc attaattaag ccttttgttt taggtgttag tggtgtatgt
     4621 aatgtaacga aatcagaatg ttgggcaatc tcatcaactg ttgccttcgt aatacttaaa
     4681 gattttgctt tttcatccgt taagtaaggg tcaaaagcta gtattttcat tccgaaactt
     4741 tgcgcacgtt tagcaacacc taaaccaatt ctaccagcac caatgacacc taatgtttta
     4801 tgataaagct cagtaccttt aaatgcattt cgattccatt ctttatttgt aagtgattgg
     4861 tgtgcttgcg gaatatttcg agccattgat aataacattg ccagtgaatg ttcagtagct
     4921 gaaatcgtat taccatctgg ggcattaata actaaaatac cttttaatgt tgcagcatta
     4981 atattaatat tatctacacc aacaccggcg cgtgcgatta cttttaaaga atcagcagca
     5041 tttatgatat tttcagtaac cgtagtttga ctacgaacga ttaaagcatg gtatgaaggt
     5101 ataattttga ttaatgcttc ttcggacaag ccagtttgaa tatctacatt gaattgttcg
     5161 tgatctaata atgctttgat accatctttt gatatgggat ctgcaacgag tacattaaat
     5221 tgcttcatga ataacctcca tatattttga tataccttta ccgatatagt taactttacg
     5281 gtgttcagtt aaaataattt ctaaagcaga tactaccgat aaaatatcga aaggactaat
     5341 tttccccata tgaccaattc ttaaaatttg acctttaaga tggccttgac caccagcaat
     5401 tgttatttta aagcgatttt taagttcatc tttgattatt ttcacttcat ttgtattagg
     5461 tttgaatgct gtaaccgttg gagatgcatc tttatcattg actaataaag ttaaatctaa
     5521 tgcttttaag gcgcttctta atgcatttct aattgcatag tgtcgtgcta ttacgtgatt
     5581 gaaaccttct gcttttacgg tttcaacgta tgcatttaca cctctaaata aagacacatt
     5641 tggtgtgaac ggtgtagaat tgtcagcttg tgacgaaatg tatttattta agtctagata
     5701 aaattttggc gtagttactt ctttgaaacg ttcttttgca cggtggctat aagctacaaa
     5761 agctaatcct ggaggtaaca taattgcttt ttgactacca gaaacaagta catcaatttt
     5821 atctttgtta atgtcaacat caacagcacc aatgcaactt acgccgtcaa ctacaaaata
     5881 aatattacta ttaaattgat tgatggcatt tcctaactcg tgaatagggt gtagcactgt
     5941 cgtagatgtt tcgcaatatt gactaaatac tgctttaact tcaacatcta aagttgaaag
     6001 gtaattgatg aaatctttaa catctacagc ttctccccat gttacgtcat aaatgtgcac
     6061 atttttgtaa taagtttgtg caatttgttt aaatcggtta ccaaaggcac ctgaaacaat
     6121 gacaacgaag tgatcttcag ggtttacaat gttcaacata ctagcctcca agacgcttgt
     6181 accgctagat gttaaaataa gtacatcatt ttgactccca aatattggct ttagaccttg
     6241 aaatgcttgt tgtgcgatgt cttcaaaatc tttagaacga tgaccaacca taggtgcttg
     6301 aatttctctc ataatggcat caggtacagg ggttgggcca ggtgttaata acaacggttg
     6361 atgataatac atttatatgc ctcctataaa taagatttca ctattttagc aaattttctg
     6421 aaaatttaaa agcctaaaaa aagtgataac gctatattgt cgaataaacg ttatcacgta
     6481 acgattttat ttggcctgaa tgatgggata gatttttatg tctacattat ttcttacagc
     6541 atttgaaatc atgcaattat tatctgcaat tgttatcaat tttggtaatc gcttttctaa
     6601 ttgtgctatt tgatcacttg gaatttcaat gtgaggatgg tgcacaattt ttgacatact
     6661 gaattttcca ttatttaaac aagctgttcc aatcgattgt tgttcaattg aaatatctgt
     6721 gaactttgca cgttcaagag tagctgctaa tgagatgata taacatgatg aagcggctga
     6781 tactaacatt tcatcgggat ttgttcctat accaacacca cctaaagaag caggtattga
     6841 aatattctct gaaagtatgt cgccttgaac gtttccgaca ttgttacgac caccttgcca
     6901 agaagtttgg actttaaagt catgttgatg caattgcttt aacctccaat ataattgtga
     6961 tagtttaatt ttagaatagt ttatcaaagt ttaacagaaa ggtgacttat caatgactct
     7021 gaataaactg aaagatgaat tacaaattgt ttcgcaccgt ggattaccga gtgattttcc
     7081 tgaaaataca atggtcggtt atcgagaggt aatggggctc aatgttgcta tgttagaaat
     7141 agatgttcat ttgaccaaag accaacattt tgttgtgata catgatgaaa caattgatag
     7201 aacatcggat ggtaaggggc gtattgctga ttacacatta tcgcaattaa aatcatttga
     7261 ttttggtagt tataaagatg ttgcttttaa gggagaacga atacccacgt tagatgaagt
     7321 actttcatta tgcttaaagt atgataaaaa gctattgatt gaattgaaaa gtccgaattt
     7381 atatccagaa atagaatgta aattgctggc atttttggaa gaaaagaaag tcgatgcgac
     7441 acaagtagtt atacaatctt ttgatatcga atgcatcgaa aagttaaaca cattgggcag
     7501 tatatatgaa ttaggtgtgc tttgtagtaa acgtaattat tggtataaaa agccaaactt
     7561 ttcaagaatt gctcaaattg ctagttatgt taatcctaat tatgcattag tggccagaaa
     7621 atttgttgat aaagcacatc atcatcaatt acaggttatg ccatacacag ttaataaatt
     7681 gaaaactgga gaaaaattaa gacaaatggg tgtagatgga ttaattacag ataatccgaa
     7741 attatttatt aagtgagacg atgaatggta atttgataga gggatgagga ttcgtatatc
     7801 gcaattgata attttaaaaa ctaatgatga aatactaaag ataattaaac aaataagact
     7861 tgtaaattct aagttgattg taaaataggg tagctccata taattttgaa tctatcattt
     7921 ttaaattaat aaaaaaaaca cccacaattg tgggtgtttg tattgaacgt attatcttga
     7981 gtagtactca acgattaatt gttcgttaat ttcagcaggt aattcgctac gttctggtaa
     8041 acgtacgaaa gtaccagtta agctgtcagc atcaaagttt aagtactcag gtacgaaatt
     8101 gttgatttca actgattcaa cgatgatgtt taatttttga gatttttcac gaactgaaat
     8161 tgtttgacca ggtttaacag aataagatgg aatatcaaca cgtttaccat ctactaagat
     8221 atgaccgtgg ttaactaatt gacgtgcttg acgacgagta cgagctaaac ctaatgaata
     8281 aacaacagcg tctaaacgac ttgctaataa aatcatgaag ttttcaccgt gtacaccgaa
     8341 ttttttacca gcgatgtcaa atgtgttacg gaattgtctt tcagtcattc catataagta
     8401 acgtaatttt tgtttttcac gtaattgtaa accatattct gataattttt tacgttggtt
     8461 tggaccatgt tgtcctggtg cgtaaggacg tttttctaat tctttaccag taccgcttaa
     8521 agagatacct aaacgacgag attttttcca gtttgaacct ctgaatcgag ccataataag
     8581 actcctcctt taattctttt ttgttgttat gaataaacaa aaaagagtgt tgcatgctta
     8641 ctaagatata ttgttttatg tgtcttcacc ttatagcgac agttacgtga cacgtccgca
     8701 ttgggaacaa catagcgctc aataatatac aactgctact ttcgttaatt cacacaaaga
     8761 ttattgtaac attttcctgc taactgtcaa cactttattg aaaatgctga tgtcctttta
     8821 tgcgagttgc ttttcaataa ttttaacaat tgcttcaaga tgttctttgt cattgtcatc
     8881 aaatcgatcc gttatagggg catcgatatc taagacgccg ataattttat catctttgaa
     8941 aattggaacg acaatctcag acttactatt agcatcacaa gcgatatgtc cttcgaattg
     9001 atggacatca gctacaactt gtgtacgacg ttctgaaacg gctgtaccgc atacaccttt
     9061 tccaattgga atgtggacac aagcggggtg tccttggaaa ggtccaagta taagttcatt
     9121 ttgttccaat aagtaaaagc caacccaatt aatttgattt agattatcat ttaataaggc
     9181 agacatgtta cttaaaatcg caatcatatg atgttcatct tcaataaggc ttgctgcttg
     9241 tttctttaat aatgtgtagt ttgttgggtt aattgttgtc atatttaaaa cctcttattt
     9301 tcatagattt tataatagta tagaatttcg aaaatattat ggcaataaat tcattttata
     9361 atttatcctt aagcaaaatt acgttataat agtaatgata aattaggagg agaag
//
LOCUS       DAPDIM010000084         9054 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000084 DAPDIM010000000
VERSION     DAPDIM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9054
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.084"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..883
                     /locus_tag="RFE25_002454"
     CDS             <1..883
                     /locus_tag="RFE25_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817488.1"
                     /translation="LFIIITITFFLMKLMPGSPFNDAKLNAEQKEILNEKYGLNDPVA
                     TQYLHYLKNVVTGDFGNSFQYHNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVA
                     AATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKLRWFPVAGWEGFSTAVLPS
                     LALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITII
                     VPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVD
                     ILYGVIDPRIRVQGGKK"
     gene            883..1953
                     /locus_tag="RFE25_002455"
     CDS             883..1953
                     /locus_tag="RFE25_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817489.1"
                     /translation="MAENKNNLSINDDHSNAAMTHTSDAIASSDFIIRELDLNQEPEM
                     QRESKNFWQDAWAQLKRNKLAVVGMIGLIIIVIFAFIGPVINKHDYAEQNVEHRNLPA
                     KIPVLDKVPFLPFDGKDADGKDAYKAANAKENYWFGTDQLGRDLWTRTWKGAQISLFI
                     GVVAAMLDIFIGVVYGAISGFFGGRVDTIMQRILEVIASIPNLIVVILFVLIFEPSIW
                     TIILAMSITGWLGMSRVVRGEFLKLKNQEFVMASKTLGASKFKLIFKHILPNTLGAIV
                     VTSMFTVPSAIFFEAFLSFIGIGVPAPQTSLGSLVNDGRAMLLIYPHELFIPAMILSL
                     LILFFYLFSDGLRDAFDPKMRK"
     gene            1969..3051
                     /locus_tag="RFE25_002456"
     CDS             1969..3051
                     /locus_tag="RFE25_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817490.1"
                     /translation="MTERILEVNDLHVSFDITAGEVQAVRGVDFYLNKGETLAIVGES
                     GSGKSVTTKAITKLFQGDTGRIKKGEILFLGEDLAKKPENELIKLRGKDISMIFQDPM
                     TSLNPTMQIGKQVMEPLIKHKNYSKAQAKKRALEILNLVGLPNAEKRFKAYPHQFSGG
                     QRQRIVIATALACEPKVLIADEPTTALDVTMQAQILDLMKELQQKIDTAIIFITHDLG
                     VVANIADRVAVMYGGQMVETGDVNEIFYDPKHPYTWGLLSSMPDLSTTNDTPLLAIPG
                     APPDLLHPPKGDAFARRSQYALDIDFKVEPPWFKVSPTHFVKSWLLDARAPKVELPEL
                     VKQRMKPMPNNYEKPLKVERVSFNEK"
     gene            3041..3982
                     /locus_tag="RFE25_002457"
     CDS             3041..3982
                     /locus_tag="RFE25_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDU2817491.1"
                     /translation="MKNDEVLLSIKNLKQYFNAGKKNEVRAIENISFDIYKGETLGLV
                     GESGCGKSTTGKSIIKLNDITSGEILYEGIDIQKIRKRKDLLKFNKKIQMIFQDPYAS
                     LNPRLKVMDIVAEGIDIHHLATDKRDRKKRVYDLLETVGLSKEHANRYPHEFSGGQRQ
                     RIGIARALAVEPEFIIADEPISALDVSIQAQVVNLLLKLQRERGITFLFIAHDLSMVK
                     YISDRIAVMHFGKIVEIGPAEEIYQNPLHDYTKSLLSAIPQPDPESERSRKRFSYIDD
                     EANNHLRQLHEIRPNHFVFSTEEEAAQLRENKLVTQN"
     gene            4001..5656
                     /locus_tag="RFE25_002458"
     CDS             4001..5656
                     /locus_tag="RFE25_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDU2817492.1"
                     /translation="MTRKFRTLILILIATIALSGCANDDGIYSDKGQVFRKILSSDLT
                     SLDTSLITDEISSEVTAQTFEGLYTLGKGDKPVLGVAKAFPEKSKDGKTLKVKLRSDA
                     KWSNGDKVTAQDFVYAWRKTVDPKTGSEFAYIMGDIKNASDISTGKKPVEQLGIKALN
                     DETLQIELEKPVPYINQLLALNTFAPQNEKVAKKYGKNYGTAADRAVYNGPFKVDDWK
                     QEDKTLLSKNQYYWDKKNVKLDKVNYKVIKDLQAGASLYDTESVDDAVITADQVNKYK
                     DNKGLNFVLTSGTFFVKMNEKQYPDFKNKNLRLAIAQAIDKKGYVDSVKNNGSIPSDT
                     LTAKGIAKAPNGKDYASTMNSPLKYNPKEARAHWDKAKKELGKNEVTFSMNTEDTPDA
                     KISAEYIKSQVEKNLPGVTLKIKQLPFKQRVSLELSNNFEASLSGWSADYPDPMAYLE
                     TMTTGSAQNNTDWGNKEYDQLLKVARTKLALQPNERYENLKKAEEMFLGDAPVAPIYQ
                     KGVAHLTNPQVKGLIYHKFGPNNSLKHVYIDKSIDKETGKKKK"
     gene            5868..7583
                     /locus_tag="RFE25_002459"
     CDS             5868..7583
                     /locus_tag="RFE25_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDU2817493.1"
                     /translation="MGKLIKYISILLIVVLVLSACGKSSNKDEGVKDATKTETSKHKG
                     GTLNVALTAPPSGVYSSLLNSTHADSVVEGYFNESLLATDKKIRPKAYIASWKDIEPA
                     KKIEFKIKKGIKWHDGNELKIDDWIYSIEVLANKDYEGAYYPSVENIQGAKDYHEGKT
                     DHISGLKKIDDYTMQVTFDKKQENYLTGFITGHLLSKKYLSDVPIKDLAKSDKIRKYP
                     IGIGPYKVKKIVPGEAVQLVKFDDYWQGKPALDKINLKVIDQAQIIKAMEKGDIDVAN
                     DATGAMAKDAKSSNAGLKVLSAPSLDYGLIGFVSHDYDKKANKTGKVRPKYEDKELRK
                     AMLYAIDREKWIKAFFNGYASEINSFVPSMHWIAANPKDLNDYKYDPEKAKKILDKLG
                     YKDRDGDGFREDPKGNKFEINFKHYSGSNPTFEPRTAAIKDFWEKVGLKTNVKLVEFG
                     KYNEDLANASKDMEVYFRSWAGGTDPDPSDLYHTDRPQNEMRTVLPKSDQYLDDALDF
                     EKVGIDEKKRKDIYVKWQKYMNDELPGLPMFQGKSITIVNDKVRNLDIEIGTDQSLYN
                     LTKEA"
     gene            7634..8620
                     /locus_tag="RFE25_002460"
     CDS             7634..8620
                     /locus_tag="RFE25_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817494.1"
                     /translation="MNNVLLEVKDLETSLKINNEWLATVENISFELSKGEVLGIVGES
                     GCGKSILSKSIIKLLPEKISKLSSGEVIFDGKRIDTLNEKQLLDIRGNDIAMIFQEPM
                     TALNPVFTIKNQLVESIKSHKKISKKEANNLAKDLLKKVGIARQDEILNSYPHQLSGG
                     MRQRVMIAMAISCSPKLLIADEPTTALDVTIQAQILDLLKELQKETQMAIMMITHDLS
                     VVAEFCDKVLVMYAGQIVEFGGIKEILHNPKHPYTQKLLSTIPKLKEGQKRLETIEGI
                     VPSIQAFHVNKCRFANRCNKKLDICNNQSPKMHVCEDVIVRCHLYKNEYKEI"
     gene            8623..>9054
                     /locus_tag="RFE25_002461"
     CDS             8623..>9054
                     /locus_tag="RFE25_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDU2817495.1"
                     /translation="MENILEVNQIKKYYKIKTGLLQKTQYVKAVDDVSFSIKKGQTFG
                     LVGESGCGKSTLGKVIIRLEDATSGSIIVNGEDITRLQGKKLRKSRQQYQMIFQDPYA
                     SLNPMQMVGDIISEPILNYKKLPKEEIKKEVLYLLKCVGLSE"
BASE COUNT         3380 a         1252 c         1715 g         2707 t
ORIGIN      
        1 tttatttatt attattacaa ttacattttt cttaatgaaa ttaatgccag gttcgccatt
       61 taacgatgct aaattaaatg ctgaacaaaa agaaatttta aatgaaaaat atggattaaa
      121 tgatcctgta gctacgcagt atttacatta tttaaaaaat gttgttacag gcgattttgg
      181 taattcattc cagtatcata atcaacctgt gtgggatttg attaaaccga gactactacc
      241 ttcttttgaa atgggtctta cagcaatgtt catcggtgtg atactgggac ttattttagg
      301 tgttgcagca gctactaaac aaaattcttg ggttgactat acaactacag ttatttcagt
      361 tattgctgta tctgtaccat cttttgtact tgctgtactt ttacaatatg tatttgcagt
      421 taaattaaga tggttcccag tagctggatg ggaaggtttt tcgaccgcgg tattaccgtc
      481 acttgcatta tctgcagctg ttttagcaac tgtcgccaga tacataagag cagagatgat
      541 agaggtatta agttcagact atattttatt agcgagagct aaaggtaatt cgacaatgcg
      601 tgtacttttt ggacatgcac ttagaaatgc tttaattcca attattacaa ttatcgttcc
      661 catgttagca agtattttaa caggcacttt aacaattgaa aatatttttg gggttcctgg
      721 attaggggat caattcgtac gttcaattac aacaaatgat ttctcagtaa tcatggcaat
      781 cacactatta tttagcacac tgtttatcgt ttctattttt attgtagata ttttgtacgg
      841 tgtgatagat ccacgaattc gtgttcaagg aggtaaaaaa taatggctga aaataaaaac
      901 aatttgtcga ttaacgacga tcattctaat gcagctatga cgcatacctc tgacgctatc
      961 gcatcatctg attttattat tagagaatta gacttgaatc aggaacctga aatgcaacga
     1021 gaaagcaaaa acttttggca agatgcttgg gctcagttaa aacgaaataa gttagctgtt
     1081 gtcggtatga taggtttaat tatcattgta atatttgctt ttatcggtcc agttataaat
     1141 aaacatgatt atgctgaaca aaatgtagaa catagaaatc ttccggcaaa aatacctgta
     1201 ttagacaaag ttccattttt accttttgat ggtaaagatg cagatggcaa ggatgcttat
     1261 aaagcagcaa atgctaaaga aaattattgg tttggtactg atcagttggg tcgagattta
     1321 tggacaagaa catggaaagg tgctcaaatt tcattgttta tcggtgttgt tgcagcgatg
     1381 ttagatattt ttattggcgt tgtatatggt gcgatttctg gattcttcgg tggacgtgtc
     1441 gatacgatta tgcaacgtat acttgaagtc atagcatcta ttccgaattt aattgtcgta
     1501 attttatttg tattaatttt tgaaccatcc atttggacaa ttatattggc tatgtctatc
     1561 acaggctggt taggcatgag cagagttgta cgtggagaat ttttaaaatt gaaaaatcaa
     1621 gagtttgtca tggcttcgaa aacattgggg gcttcaaaat tcaaattgat atttaagcat
     1681 attttaccta atacgttagg tgctatcgtg gttacatcaa tgtttacagt acctagtgct
     1741 attttcttcg aagcattttt aagtttcatt ggtataggtg tacctgcacc tcaaacatcg
     1801 ttagggtcat tagtaaatga tgggcgcgca atgttattaa tttatccaca tgaattattt
     1861 ataccagcaa tgattttaag tttattaatt ctattctttt acttatttag tgatggatta
     1921 cgtgatgcat ttgatccgaa aatgcgtaaa taaaaggggg catagcatat gactgaaaga
     1981 atattagaag taaatgattt gcatgtttcc tttgatatta cagcagggga agtgcaggca
     2041 gtgagaggtg tagattttta tttaaacaag ggggaaacat tggcaattgt tggtgaatca
     2101 ggttcaggta aatctgtaac aacaaaagca attacaaaat tattccaagg ggacacagga
     2161 agaattaaaa agggagaaat tttattttta ggggaagatt tagcaaaaaa acctgaaaat
     2221 gagttaatta aattacgtgg caaagatatt tcaatgatct ttcaagatcc aatgacatct
     2281 ttaaacccaa cgatgcaaat tggtaaacaa gtcatggaac cattaattaa gcacaaaaat
     2341 tatagtaaag cacaagctaa aaagcgcgca ttggaaatac taaatcttgt aggtttacca
     2401 aatgcagaaa aaagatttaa agcatatcct catcaatttt caggtggaca aaggcaaaga
     2461 attgttattg caaccgcatt agcttgtgaa cctaaagtgc tcattgctga tgaaccaacg
     2521 actgcattag acgtaacgat gcaggcacaa attttagatt taatgaaaga actacaacaa
     2581 aaaatcgata cagcaattat ttttataacg catgatttag gggttgttgc gaatattgct
     2641 gatagagtgg cagttatgta tggtggtcaa atggttgaaa caggagatgt taacgaaata
     2701 ttttatgatc caaagcatcc atatacatgg ggattattat cgtcaatgcc tgatttatca
     2761 acaacaaatg acacaccatt actagcgatt cctggagcgc cacctgattt attacaccca
     2821 cctaaaggtg atgcatttgc gagacgtagt caatatgcat tagatattga ttttaaagta
     2881 gaaccaccgt ggtttaaagt ttcaccgaca cattttgtga aatcttggtt attagacgca
     2941 cgtgcaccaa aagttgaact acccgagctg gtaaaacaac gtatgaaacc gatgcctaat
     3001 aattatgaaa aaccactcaa ggtagaaagg gtgtcgttca atgaaaaatg atgaagtgct
     3061 attatctatt aaaaatttaa agcaatattt taacgcagga aagaaaaacg aagtgagagc
     3121 gattgaaaat atttcgtttg atatatacaa aggggaaaca ttaggtttag taggagaatc
     3181 ggggtgtggt aaatctacaa ctggtaaatc aattattaaa cttaatgata ttacaagtgg
     3241 agaaattttg tatgagggta ttgatataca aaagattcgt aaacgtaaag atttgcttaa
     3301 atttaataaa aagatacaga tgatttttca agacccatat gcgtctttaa atcctaggtt
     3361 aaaagtaatg gatatagtag ctgaaggtat tgatatccat catttagcaa ctgataagcg
     3421 tgaccgaaaa aaacgtgtct atgatttact tgaaactgtt ggattaagta aagaacatgc
     3481 caatcgctat cctcatgaat tttcaggtgg acaacgccaa cgtattggaa ttgcccgtgc
     3541 attagccgtt gaaccagaat tcattatcgc ggacgaacca atatcggcat tggatgtttc
     3601 aatccaagct caagtagtta atttattatt aaaattacaa cgtgaaagag ggattacgtt
     3661 cctatttata gctcatgatc tatcaatggt gaagtatatt tcagatcgta ttgcagtcat
     3721 gcattttggg aaaatagttg aaattggacc ggcagaagaa atttatcaaa atccattaca
     3781 cgattatact aagtctttat tatcagccat tccacaacct gatcctgaat cagaacgcag
     3841 tcgcaaacga tttagttata ttgatgatga agcaaataat catttaagac aattacatga
     3901 aattagaccg aatcactttg tctttagtac tgaagaagaa gcggcacaac tacgagaaaa
     3961 taaattggtg acacaaaatt aaggggaagg gggaaatgca atgacgagaa aatttagaac
     4021 acttatttta attttgattg ctacaattgc attaagtggt tgtgctaatg acgatggtat
     4081 ttattcagat aaaggtcaag tattcagaaa aattttgtca tcagacttaa catcccttga
     4141 tacatcatta ataacggatg aaatatcttc tgaagtgact gcgcaaacat tcgaaggttt
     4201 atacacatta ggaaaaggtg acaaaccggt gttaggtgtt gcgaaagctt ttcctgaaaa
     4261 gagtaaagat ggtaaaactt taaaggttaa attaagaagc gatgctaaat ggagcaatgg
     4321 tgacaaagtg actgcacaag actttgttta tgcttggaga aaaacagttg accctaaaac
     4381 aggttctgaa tttgcataca ttatggggga cattaaaaat gcgagtgata ttagtactgg
     4441 taagaaacct gtagagcaat taggtatcaa agcattaaat gatgaaacat tacaaattga
     4501 attagaaaag ccggttccat atattaatca attattagca cttaatacct ttgcacctca
     4561 aaatgaaaaa gttgccaaaa aatatggtaa aaattacggt acggcagctg atagagcggt
     4621 atacaatggt ccatttaaag ttgatgattg gaaacaagaa gataaaacct tactatctaa
     4681 aaatcagtat tattgggata aaaagaatgt aaaattagat aaagtgaatt ataaagttat
     4741 taaagactta caagccggtg catcattgta tgatactgaa tcagtagatg acgcagttat
     4801 tactgcagat caagtaaata aatataaaga caacaaagga ttaaactttg tgttaacgtc
     4861 tgggacattt tttgtaaaaa tgaatgaaaa acaatatcct gattttaaaa acaaaaattt
     4921 aagattggct atcgcacaag caatagataa aaaaggatac gttgattcag tgaaaaacaa
     4981 tggctcaatt ccttccgata cactaacagc caaaggaatt gcgaaagcgc ctaatggcaa
     5041 agattatgcg agtaccatga attcgccttt aaaatataat cctaaagaag caagagcaca
     5101 ctgggacaaa gctaaaaaag agttaggtaa aaatgaagtg acattttcaa tgaacacaga
     5161 agatacacca gatgcaaaaa tatctgctga atatatcaaa tcgcaagttg agaaaaattt
     5221 accaggagtt actttgaaaa ttaagcaatt accgtttaaa caaagagtat cactagaact
     5281 gagtaacaat tttgaagcat cacttagtgg ttggtctgca gattaccctg atcctatggc
     5341 ttatttagaa acaatgacca caggtagcgc acaaaataat acagactggg gtaataaaga
     5401 atatgatcaa ttacttaaag tagcaagaac caaattggca cttcaaccga acgaacgata
     5461 tgaaaacttg aaaaaagcag aagaaatgtt cctaggagat gcaccggtag caccaattta
     5521 tcaaaaaggt gttgcacatt taacaaatcc tcaagtaaaa ggattaattt accataaatt
     5581 tggtccaaat aactcactta aacatgtata tattgataaa tcgatagata aagaaacagg
     5641 taagaagaaa aaataatatg ctttgtaaat taggctggag acatatctcc agtctttttg
     5701 tgttggataa aaactttggg aataaaaatt taaaataagt cgttttttaa attactgaaa
     5761 ttgattaaat gcataaataa ctgaatattc taaaaataaa cttgtaataa ttttttctat
     5821 gagtaaacta aaaagaaaaa attagattga aagtaggagg catatgtatg gggaagctaa
     5881 ttaaatatat ttcaatactt cttattgtcg ttttagtgtt gagtgcttgc ggaaaaagca
     5941 gtaataaaga tgaaggagta aaagatgcta ctaaaacgga aacctcaaaa cataaaggtg
     6001 gtaccttaaa tgtagcatta acagcaccgc caagtggtgt ttattcttcg ttattaaata
     6061 gtacacatgc agattctgta gttgagggat attttaacga aagcttatta gcaactgata
     6121 aaaaaatacg tcctaaggca tatattgctt catggaagga catcgagccg gctaagaaaa
     6181 tagaatttaa aattaaaaaa ggtattaaat ggcatgatgg taatgaattg aaaattgatg
     6241 attggattta ttcaattgaa gtcttagcta acaaggacta cgaaggtgct tattatccaa
     6301 gtgtagaaaa tatccaaggt gcgaaagatt atcatgaagg aaaaactgat catattagcg
     6361 gattgaagaa aatagatgac tacactatgc aggttacatt tgataaaaaa caagaaaatt
     6421 acttaacagg atttattact ggacatttat taagtaaaaa atatttatca gatgtaccaa
     6481 ttaaagattt agcgaaatca gataaaatcc gaaaatatcc tattggtatt ggaccgtata
     6541 aagttaagaa aatcgttcca ggtgaggctg ttcaactcgt taaatttgat gattattggc
     6601 aaggtaagcc tgcactagac aaaatcaatt taaaagttat tgatcaagct caaattatta
     6661 aggcaatgga aaaaggcgat attgatgttg cgaatgatgc taccggtgca atggcaaaag
     6721 atgctaagtc atctaatgct ggtctcaagg tattatctgc gccaagctta gactacggtt
     6781 taataggatt cgtatctcat gattacgata aaaaagctaa taaaactggt aaagtgagac
     6841 caaaatatga agacaaagaa ttacgtaaag caatgcttta tgcaattgat agagaaaaat
     6901 ggattaaagc gtttttcaat ggttacgcta gtgaaatcaa tagttttgta ccatctatgc
     6961 attggatagc agccaatcct aaggacctaa atgattacaa atatgatcct gaaaaagcta
     7021 aaaaaatctt agataagtta ggttataaag atagagatgg tgacggattt agagaagatc
     7081 ctaaaggtaa taaatttgag attaacttta aacattattc aggttcaaat cctacttttg
     7141 aaccaagaac tgctgcgata aaagatttct gggaaaaagt tggcttgaaa acaaatgtga
     7201 agttagtaga attcggtaaa tataatgaag acttagcaaa tgcatctaaa gatatggaag
     7261 tgtacttcag atcatgggca ggaggtacag atccagatcc atcagattta taccacactg
     7321 atagacctca aaatgaaatg agaacagttt taccaaaatc agatcaatat ttagatgatg
     7381 cattagactt cgaaaaagta ggcattgatg aaaagaaacg taaagatatt tatgttaaat
     7441 ggcaaaaata tatgaatgat gagttacctg gattaccaat gttccaaggt aaatcgataa
     7501 ctattgttaa cgataaagta cgaaacttag acattgaaat tggaactgat caaagtttat
     7561 ataatttaac taaagaagct tagtaatgta acctcgacga ttttgtcgag gtttacttat
     7621 atggggggat gttatgaata atgtattgtt agaggttaaa gatttagaaa catcattaaa
     7681 aataaataat gaatggttag caactgttga aaatatttct tttgaattat ctaaaggaga
     7741 agttttgggt atagtagggg aatctggttg cggtaagtcc atattaagta agtcaattat
     7801 taaattatta ccagaaaaga tatctaaact aagtagtgga gaagttatat ttgatggtaa
     7861 acgaatcgat acgctcaatg agaagcaatt gctagatatt cgaggaaatg atattgctat
     7921 gatttttcaa gaacctatga ctgctttaaa tcctgtattt accataaaaa atcaacttgt
     7981 ggaatctata aaatcacata aaaaaatttc taaaaaagaa gcaaataact tagcaaaaga
     8041 tttactaaaa aaagttggaa ttgctagaca agatgaaata ttaaatagct atcctcatca
     8101 attatctggt ggtatgagac aaagagtaat gattgcaatg gccatttcat gttctcctaa
     8161 attattaatt gctgatgaac ctacaacagc attggatgtc acgattcaag cgcaaatatt
     8221 agacttatta aaagaattgc aaaaggaaac gcaaatggca attatgatga ttacacatga
     8281 tttgagtgta gttgctgagt tttgcgataa agtcttagtt atgtatgcag gtcaaattgt
     8341 agaatttgga ggcataaaag aaatactaca caatccgaaa catccttata cccaaaaatt
     8401 attatcaaca attccaaaac ttaaagaagg gcagaaacga cttgaaacga tagaaggaat
     8461 tgtgccatca atccaagcat ttcacgttaa taagtgcaga tttgcaaata gatgtaacaa
     8521 aaaactggat atttgtaata atcaatctcc taaaatgcat gtttgtgaag acgtcattgt
     8581 acgttgtcat ttgtacaaaa atgaatataa ggagatataa gaatggaaaa tattttagaa
     8641 gtcaaccaaa taaaaaaata ctacaaaatt aaaactggat tattacaaaa aactcagtac
     8701 gttaaagctg ttgatgacgt atcgttttca ataaaaaaag gacaaacttt tggattagta
     8761 ggagaatcgg gttgtggtaa gtcaacgtta ggtaaagtga ttatcaggct tgaagatgca
     8821 acttcaggtt caataattgt taatggtgaa gatataacaa gattacaagg taaaaaactc
     8881 agaaaatcac gacaacaata tcagatgata tttcaagatc cgtatgcatc attgaatccg
     8941 atgcaaatgg ttggagatat catttcagaa cctattttaa attataaaaa attgccaaaa
     9001 gaagaaataa aaaaagaagt actatattta ttaaaatgtg ttggcctaag tgaa
//
LOCUS       DAPDIM010000085         9052 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000085 DAPDIM010000000
VERSION     DAPDIM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9052
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.085"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(190..459)
                     /locus_tag="RFE25_002462"
     CDS             complement(190..459)
                     /locus_tag="RFE25_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817496.1"
                     /translation="MAENNQNSLVTKIATYGSFIAIASFVILFISIFLKFSFNIEFIA
                     TIMNICRYTLILGFILMSLPDVVDKNIKKIIFDAFIIIVFIFFLL"
     gene            773..1459
                     /gene="mtnN"
                     /locus_tag="RFE25_002463"
     CDS             773..1459
                     /gene="mtnN"
                     /locus_tag="RFE25_002463"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDU2817497.1"
                     /translation="MIGIIGAMEEEVTILKNKLTQLSEISVAHVKFYTGILKDREVVI
                     TQSGIGKVNAAISTTLLINKFKPDVIINTGSAGALDESLNVGDVLISDDVKYHDADAT
                     AFGYEYGQIPQMPVAFQSSKPLIEKVSQVVQQQQLTAKVGLIVSGDSFIGSVEQRQKI
                     KKAFPNAMAVEMEATAIAQTCYQFNVPFVVVRAVSDLANGEAEMSFEAFLEKAAVSSS
                     QTVEALVSQL"
     gene            1479..2006
                     /locus_tag="RFE25_002464"
     CDS             1479..2006
                     /locus_tag="RFE25_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HDU2817498.1"
                     /translation="MGLVRKFFMPNSYVQSIFQIDLDKLVDKGVKGIITDLDNTLVGW
                     DVKEPAERVKAWFKEANEKGITITIVSNNNESRVASFSQHLDIDFIFKARKPMGKAFD
                     KAITKMNIRPDQTVVIGDQMLTDVFGGNRRGLYTIMVVPVKRTDGFITKVNRLIERRL
                     LRHFSKKGYITWEEN"
     gene            2007..3107
                     /gene="yqeH"
                     /locus_tag="RFE25_002465"
     CDS             2007..3107
                     /gene="yqeH"
                     /locus_tag="RFE25_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HDU2817499.1"
                     /translation="MSDILKCIGCGAPLQSEDKNKPGFVPEHNMFRDDVICRRCFRLK
                     NYNEVQDVGLESEDFLKLLSGLADKKGIVVNVVDVFDFEGSFINAVKRIVGNKKIILA
                     ANKLDLLPKQINKRRVKEWLKRTARKYGLEADDVVLISAEKGWGIDDLLSSIANIREN
                     EDVYIVGTTNVGKSTLINKLIEASVGEKDVVTTSRFPGTTLDMIDIPLDESSFMYDTP
                     GIIQDHQMTHLVSEKELKIIMPKKEIKQRVYQLNEAQTLFFGGLARIDYVSGGKRPLV
                     CFFSNDLNIHRTKTEKANDLWRNQLGDLLTPPGNPQNFDLNELKAVRLETGKEKRDVM
                     ISGLGFITIGPGAKVIVRVPKNVDVVLRNSIL"
     gene            3121..3927
                     /gene="aroE"
                     /locus_tag="RFE25_002466"
     CDS             3121..3927
                     /gene="aroE"
                     /locus_tag="RFE25_002466"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDU2817500.1"
                     /translation="MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHL
                     IKEIISKKELDGFNITIPHKERIIPYLDYVDEQAINAGAVNTVLIKDGKWIGYNTDGI
                     GYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
                     INQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPI
                     LEEAERKGNHIYNGLDMFVYQGAESFKIWTNKDADINSMKTAVLQQLKGE"
     gene            3931..4221
                     /gene="yhbY"
                     /locus_tag="RFE25_002467"
     CDS             3931..4221
                     /gene="yhbY"
                     /locus_tag="RFE25_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDU2817501.1"
                     /translation="MLTGKQKRYLRSLAHNIDPIFQIGKGGINENMIKQIDDTLENRE
                     LIKVHVLQNNFDDKKELAETLSEATRSELVQVIGSMIVIYRESKENKEIELP"
     gene            4224..4793
                     /gene="nadD"
                     /locus_tag="RFE25_002468"
     CDS             4224..4793
                     /gene="nadD"
                     /locus_tag="RFE25_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate (nicotinamide) nucleotide
                     adenylyltransferase"
                     /protein_id="HDU2817502.1"
                     /translation="MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPL
                     KKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELY
                     FVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIR
                     QRVSEGKSIQVLVPKSVENYIKGEGLYEH"
     gene            4783..5367
                     /gene="yqeK"
                     /locus_tag="RFE25_002469"
     CDS             4783..5367
                     /gene="yqeK"
                     /locus_tag="RFE25_002469"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDU2817503.1"
                     /translation="MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVE
                     LAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEV
                     LMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISK
                     RTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD"
     gene            5368..5721
                     /gene="rsfS"
                     /locus_tag="RFE25_002470"
     CDS             5368..5721
                     /gene="rsfS"
                     /locus_tag="RFE25_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDU2817504.1"
                     /translation="MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNN
                     ERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEK
                     LYQDAPLESYGQVAY"
     gene            5724..6440
                     /locus_tag="RFE25_002471"
     CDS             5724..6440
                     /locus_tag="RFE25_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDU2817505.1"
                     /translation="MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGT
                     GSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDS
                     LNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWD
                     AVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFT
                     DFNIDEHNEDTERLFFIAKK"
     gene            6480..7166
                     /locus_tag="RFE25_002472"
     CDS             6480..7166
                     /locus_tag="RFE25_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001802022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HDU2817506.1"
                     /translation="MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYT
                     SRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMT
                     SKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
                     GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKT
                     FDKLKSYFTI"
     gene            7258..7719
                     /locus_tag="RFE25_002473"
     CDS             7258..7719
                     /locus_tag="RFE25_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HDU2817507.1"
                     /translation="MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYN
                     GSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCT
                     KSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG"
     gene            7724..>9052
                     /locus_tag="RFE25_002474"
     CDS             7724..>9052
                     /locus_tag="RFE25_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDU2817508.1"
                     /translation="MLYVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPIS
                     LFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEI
                     YPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEK
                     HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAI
                     VFLIYQPLKRLNLPLFVIKGITINVLTLYAQYTNYAPSAVRAIIMTTLVLLITKQIKI
                     KGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFI
                     AQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYL
                     VDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRK"
BASE COUNT         3283 a         1148 c         1651 g         2970 t
ORIGIN      
        1 aatcattaat aatctttgac agtgaaatat aaagtacctg acattatatt gttacaaatg
       61 aaaacagcag taaggatgct aacacttaga aaagtcttac tgctattttc tattagaatt
      121 atctttaatg cacacaggaa ttcgatacga aacaaatatg attaactgtg taattacaaa
      181 ataaaactac tatagtaaaa agaagataaa gacgatgata ataaatgcat cgaatataat
      241 tttcttgatg tttttatcaa caacatcagg taaggacata agtataaatc ctagaattag
      301 agtgtagcga catatgttca taattgttgc tataaactcg atattaaatg aaaactttaa
      361 aaatatactt ataaataaaa tgacaaacga cgcaattgca ataaaactgc cgtatgtagc
      421 tatctttgtt acgagactat tttgattatt ttcagccatt gtaaaatcct cttatttcat
      481 cattattatt ttaaacatat cattttcctg ttatttaata aagtttcttg acacgattgg
      541 ttgatgtaat tgatatgatt agtttttgaa aaatagacaa attagaagca tcgaattcac
      601 tgttatgagt tcaaaaataa ttatttatga taccaagtta ttgaaagagc tttttataaa
      661 aataaagcaa aagttttata cagtaatgaa aatcatgata cttgtcgttg tagtgattaa
      721 aatgtgataa aataacaaat gctaggattt tttaaaagag gtgaatcaaa ggatgattgg
      781 tataattggt gccatggaag aagaagtaac aatattaaaa aataaattaa cacaattaag
      841 cgaaatttca gttgcacatg ttaaatttta tactggcatt ttaaaagata gagaagtagt
      901 gattacccaa agtggcattg gaaaagttaa tgctgcaatt tctacgacat tattaattaa
      961 taagtttaaa ccggacgtca ttattaatac aggttctgct ggagctttag atgaaagttt
     1021 aaatgtaggt gacgttctta taagtgatga tgtaaaatat catgatgcgg atgcaacagc
     1081 atttggttat gaatatggac aaataccaca gatgccggta gcatttcaat caagtaaacc
     1141 tttaatagaa aaagtatctc aagttgtaca acaacaacaa ttaacagcta aagtaggctt
     1201 aattgtaagt ggtgatagct ttatcggtag tgttgaacaa cgccaaaaaa ttaaaaaagc
     1261 atttccaaat gcgatggcgg ttgaaatgga agcaactgca attgcacaaa catgttatca
     1321 atttaatgta ccatttgttg tagttcgtgc agtttcagac ttagcaaatg gagaagcgga
     1381 aatgagcttc gaagcatttt tagaaaaagc agctgtatca tcaagtcaaa ctgttgaagc
     1441 attagtgtct caattataaa aaggtaaagg tgagttaaat gggtttagtt cgcaagtttt
     1501 ttatgccgaa ttcatatgtt caatcaatat ttcaaattga tttagacaag ttagtggaca
     1561 aaggcgttaa aggtattatt acagatttag ataatacgct agtaggttgg gatgttaaag
     1621 aacctgcaga acgtgttaaa gcatggttta aggaagctaa tgaaaaagga atcactatta
     1681 caatcgtgtc taataataat gagtctcgtg ttgctagttt tagtcagcat ttagacatcg
     1741 attttatttt taaagcgaga aagccaatgg ggaaagcgtt tgataaagca ataactaaga
     1801 tgaatatcag accagatcaa actgttgtta taggtgacca aatgcttact gatgtatttg
     1861 gtggtaatcg tcgaggtcta tatacaatta tggttgttcc agttaaacga actgatggct
     1921 ttattactaa ggttaataga ttaattgaaa gacgattatt acgtcatttc agtaaaaaag
     1981 gttatatcac atgggaggaa aattgattgt ctgacatttt aaaatgtatc ggttgtggtg
     2041 cgccacttca atctgaagat aaaaataaac ctggttttgt accagagcat aatatgtttc
     2101 gtgatgacgt gatttgcaga cgttgtttcc gcttgaaaaa ttataacgaa gttcaagatg
     2161 taggattaga aagtgaagac tttttaaaat tattatcagg acttgcggat aaaaagggta
     2221 ttgtcgtcaa tgtcgtggat gtatttgact ttgaaggatc atttattaat gcagttaaac
     2281 gtattgtcgg aaacaaaaaa atcattttag cagcaaataa attggattta ttgccgaaac
     2341 aaattaataa acgtcgagtt aaagaatggt taaaacgaac agcaagaaaa tatggtttgg
     2401 aagctgacga tgtcgtatta atttcagctg aaaaaggctg gggcatagac gacttattat
     2461 catcaattgc gaatattcga gaaaatgaag atgtgtatat tgtagggaca acgaatgttg
     2521 ggaaatctac attgattaat aaactgattg aagctagtgt tggtgaaaaa gatgtagtaa
     2581 caacttcaag attccctgga acaactttag atatgataga tattccttta gatgaatcat
     2641 catttatgta tgatacacca ggtattattc aagatcatca aatgacgcat ttagttagtg
     2701 aaaaagaatt gaaaattatt atgcctaaga aagaaataaa acaacgcgta tatcaattaa
     2761 atgaggcgca gacattattc ttcggcggtc tagcgcgcat agattatgta tcaggtggta
     2821 aacgtccgtt agtttgtttc ttttctaatg acttgaatat acatcgtact aaaacggaga
     2881 aggctaatga tttatggcgt aatcaacttg gcgatttatt aacgccacct ggaaatccac
     2941 aaaattttga tcttaatgag ttaaaggctg ttagacttga aacaggcaaa gagaaacgtg
     3001 atgttatgat ctctggtcta ggctttataa ctataggacc aggagctaaa gtaatcgttc
     3061 gtgttcctaa aaatgttgat gttgtattaa gaaattctat tttataaggt gatttaaaaa
     3121 atgaaatttg cagttatcgg aaatcctatt tcacattcct tgtcgcccgt tatgcataga
     3181 gcaaatttta attctttagg attagatgat acttatgaag ctttaaatat tccaattgaa
     3241 gattttcatt taattaaaga aattatttcg aaaaaagaat tagatggctt taatatcaca
     3301 attcctcata aagaacgtat cataccgtat ttagattatg ttgatgaaca agcgattaat
     3361 gcaggtgcag ttaacactgt tttgataaaa gatggcaagt ggatagggta taatacagat
     3421 ggtattggtt atgttaaagg attgcacagc gtttatccag atttagaaaa tgcatacatt
     3481 ttaattttgg gcgcaggtgg tgcaagtaaa ggtattgctt atgaattagc aaaatttgta
     3541 aagcccaaat taactgttgc gaatagaacg atggctcgtt ttgaatcttg gaatttaaat
     3601 ataaaccaaa tttcattggc agatgctgaa aagtatttag ctgaattcga tatcgttatt
     3661 aatacaacac cagcgggtat ggctggaaat aacgaaagta ttattaattt aaaacatctt
     3721 tctcccaata ctttaatgag tgatattgtt tatataccgt ataaaacacc tattttagag
     3781 gaagcagagc gcaagggaaa ccatatttat aatggcttag atatgtttgt ttaccaaggt
     3841 gcggaaagct ttaaaatttg gactaataaa gatgctgata ttaattctat gaaaacagca
     3901 gttttacaac aattaaaagg agaataacat atgcttactg gcaaacaaaa aagatactta
     3961 agaagtttag cacacaatat tgatccgatt tttcaaattg gaaaaggcgg tatcaacgaa
     4021 aatatgatta aacaaataga tgatacgtta gaaaacagag aattgattaa agtacatgta
     4081 ctacaaaata actttgatga taaaaaagaa ttagctgaaa cattaagcga agctacgcgt
     4141 agtgaattag tgcaagtgat tggatctatg atagtgattt atagagaatc taaagaaaat
     4201 aaagaaattg aattgccata ataatgaaaa agatagtact ttacggcggt cagtttaacc
     4261 ctatccatac tgcacatatg atagtagcta gcgaagtatt tcatgaatta cagccagatg
     4321 aattttattt tttacctagt tttatgtctc cattgaaaaa gcacaataat tttatagatg
     4381 ttcagcacag attaacaatg atacagatga ttatcgacga gcttggtttt ggagatattt
     4441 gcgacgatga aattaaacgt ggtggtcaga gttataccta tgacacgatc aaggcattca
     4501 aggagcaaca caaagacagt gagttgtact ttgttattgg gacggatcag tataaccaac
     4561 tagagaaatg gtatcaaatt gaatacttaa aagaaatggt tacttttgta gttgtaaatc
     4621 gagacaaaaa tagtcaaaat gttgaaaatg ctatgattgc aattcagata cctagggtag
     4681 atataagttc gacaatgatt cgacaaagag ttagtgaagg gaaatctatc caagttcttg
     4741 ttcctaaatc cgttgaaaac tatattaagg gggaaggatt atatgaacat tgaaaaagca
     4801 aaacggcttg caaaagagaa actgccagag aaacgttata atcattcttt aagagttgca
     4861 gaaacagcga ttaaattggc agaaatttat gatggagaca ctagtaaagt agaattagca
     4921 ggtgtattac atgatttctg taaatatgat gatttaggta aaatgtatca aattgttcga
     4981 caatacgaat taggtaatga tctactgagt tatggtagtg aaatattgca tggccctgtg
     5041 tgtgcagcaa tcatggaaca tgaatatggt atcaatgatg aggaagtatt aatggctatc
     5101 aaataccata ctactggacg tcaacaaatg acaaaaactg aaaaactgat ttttattgct
     5161 gattacatcg aacctggaag aacaatccca ggagttgatg atattcgaga tatggcatac
     5221 aatcaaggta gtttagataa gacaatttat gaaatttcta aacgcacagt actattttta
     5281 atacagaaag atattacggt atataataag acgattgact gtttaaatta ttataactat
     5341 agtgacgaaa gaataaagga tgattaaatg aattcacaag aattattagc aattgctgtg
     5401 gatgcaattg acaataaaaa aggcgaagat acgatttctt tagaaatgaa aggtatcagc
     5461 gatatgacag attattttgt tgtaacgcac ggaaataatg aacgacaagt tcaagcgatt
     5521 gctagagcgg tgaaagaagt agccaatgaa caaaatatag aagtaaaacg tatggaagga
     5581 tacaatgaag cgcgttggat attaattgac ttagctgatg ttgtggtaca tgttttccat
     5641 aaagacgaaa gaaattatta taatattgaa aagttatatc aagatgcacc attagaatca
     5701 tatggtcagg ttgcgtatta attatgtcgc aatatgcaga aatgagccta gtgtacgatc
     5761 aattgactca agatcaacca tatgaaaaat ggtttgaaat tgtaaaaaat cactgcaaag
     5821 atgaatcaaa tattttagat attggatgcg gtactggtag tttaacagtt caattagaag
     5881 ctttaggtaa tgttactggt atggatttaa gtgttgatat gttgactgtt gcagctcaaa
     5941 aatcagcaaa tgtaaattgg cttgaaggag atatgacatc ttttgatttg caacaacaat
     6001 ttgatatcat cactattttt tgtgactctc taaattattt gcaagatgaa actgcagtga
     6061 ttgaaacatt catcaatgtt tatcatcatc tgactgattc aggtgtattt atttttgatg
     6121 tacatactgt ttataaaatg atgactttgt ttaataatca aagttatatt gatgataaag
     6181 gggacatttt tttagcatgg gatgctgtgc aaggagattt acctttaagt gtttatcatg
     6241 atatgacatt tttcattcga catgaagatg aaacatattc aagatttgat gagtctcatt
     6301 ttcagagaac atttgatgaa aagacatatt tgtcttggtt agctcaagtc ggttttaaac
     6361 atgttgaaac atttactgat tttaatatag atgaacataa tgaagataca gaaagattgt
     6421 ttttcattgc gaaaaaataa aagtaaaacc actcgctcag acgtgtataa agttgaggag
     6481 tggttttatt gtatcaattt ttattacgct ataaagattt tttaactcag tggaagttat
     6541 atattataag tgctgttgtt ttaattatgg tattaattgg ttttatattc tggagacaag
     6601 atgattatac ttcaagaaat tttgaaaata aagatactgc tctgaaacaa agcactagtg
     6661 aaaataatag tttgtccaaa ttagaagatg tccaggtcaa agatggagat aattccaaaa
     6721 ataaaggtcc tgtatatgtc gatgtaaaag gtgctgttaa acatcctaat gtttataaaa
     6781 tgacatctaa ggatagagta gttgatttac ttgataaagc acaattattg gatgatgcag
     6841 atgtaagtcg aattaatttg tctgaaaaat taacagatca aaaaatgatt ttcatacctc
     6901 ataaaggaca aaagaatgtt gaaccacaaa ttgaagtaaa cagtgtgcac gtaaaaaatg
     6961 ggaacacaaa taatactaaa gtaaatttaa ataccgcatc tgtatcagaa ttgatgtctg
     7021 ttcctggagt agggcaagct aaagctaatg caattgttga atatcgcaac caacaaggtg
     7081 catttcaaga aattgacgat ttgaaaaaag taaaaggttt tggaagtaaa acttttgata
     7141 aactgaaatc ttatttcacg atataatgga ttattttaat tgcaaatttt attttttgtg
     7201 attaatctta tattattaga aaatgttact aaattttaag tatggaaggt gaacatcttg
     7261 gaaagaatca aatgggaaga atattttatg gcacaaagtc atttgctagc attacgttca
     7321 acttgtcaaa gattatctgt aggtgcaacg attgttaagg ataatcgtat tattgctggt
     7381 ggttataatg gctctgtagc tggcgaggtg cattgtatag atgaaggatg tttaattgaa
     7441 gatggacatt gtatcagaac gatacatgca gaaatgaatg ctttattaca atgtgcaaaa
     7501 caaggtgtat ctactgaagg tgcaacaatc tatgttactc attttccatg cctaaattgt
     7561 acaaagtcaa ttattcaagc aggtataaag cgtatctact atgcagaaga ttatcataac
     7621 catgaatatg caactaaatt actcaaacaa tctggtattg aatttaaaaa aattccattt
     7681 tcaccagaat atgttgctaa atatctgact aaaggttaat gttttgctgt atgtcgcgtt
     7741 atcaatgatt gtaggagtgc tttggaattc tagcaaagtg ctctctacat ttcttttcat
     7801 tttacttttg tatattactt atcgtaaaaa taaaatcgtt tatgccccta tttctctctt
     7861 tttaatcatt ttctcctcat ggtatttaca ttattcacaa caagcaatat ttaattatat
     7921 caattatatt gaacgtaatt ctcagtttaa tgagcgtgct caagtaatcc aaattcaacg
     7981 tcaaggtagt gacacatata aaggtaggtt gagtttaaaa aatgaaatat atcctttctt
     8041 tttaacagat aaaaagaatt ttgatttaaa gaaaattgaa agtcgtaatt gtattgttaa
     8101 aggacaattc aaagttaatg aaaataagtt tgtaactctt aaattacaaa gtatagttgt
     8161 acaaagctgc ctagaatcga accggtctaa tttaattgag aaacataaac agtttataat
     8221 gaatcgaatt tatgattcgg gtattaagtt tccggatcgt attatggcat tgattactgg
     8281 tgacgtaaaa gaaattaatg agcaatttaa ggaacgtgtt aaagagatag gtatatatca
     8341 tttgctggca gttagtggct cgcatatagc tgcaattgta ttcttaattt accaaccttt
     8401 aaaacgatta aatttacctt tatttgtcat taaaggaatt acaatcaatg tattaacttt
     8461 atatgctcaa tacacaaatt atgcacctag tgctgtaaga gctataataa tgacaactct
     8521 tgtactgctt attactaagc aaattaaaat aaagggtatt cagctattag catttgcatt
     8581 tataattatg tttattttaa acccactagt tgtttatgat attggatttc aattttcatt
     8641 catcatttca ttttttatta tgctactttt tcctttttta cagcaattgt caaagttaca
     8701 atcattattc ataattacgt ttattgcaca attagcttca tttatcgttg ccattccaaa
     8761 ctttcatcaa cttcaatggg tgggattttt atctaatttg atttttgtac cgtactattc
     8821 gattatattg tttccgctat ctattttatt ctttattaca agtcatttta ttgtgggatt
     8881 aacgccgcta aattacttgg ttgacctaag ttttaatttt catgactggt tactagacct
     8941 attcacaaga attaagcaat cacatttttc tgttcccaag tttaatgatt ggatatttat
     9001 aatatttata atttctgttt attacatatt ttggttattg gctaaacgta aa
//
LOCUS       DAPDIM010000086         8998 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000086 DAPDIM010000000
VERSION     DAPDIM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8998
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.086"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(65..571)
                     /locus_tag="RFE25_002475"
     CDS             complement(65..571)
                     /locus_tag="RFE25_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817509.1"
                     /translation="MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQ
                     SLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTH
                     ISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIK
                     LYRIDLEK"
     gene            complement(707..1507)
                     /locus_tag="RFE25_002476"
     CDS             complement(707..1507)
                     /locus_tag="RFE25_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2817510.1"
                     /translation="MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAQLA
                     KSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADI
                     SVRYPEFTSSLMLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRK
                     MNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLE
                     AKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTASFINKHHDEKHV"
     gene            complement(1491..2210)
                     /locus_tag="RFE25_002477"
     CDS             complement(1491..2210)
                     /locus_tag="RFE25_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDU2817511.1"
                     /translation="MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQL
                     ADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTL
                     YTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFED
                     MIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVE
                     ELLTILPIKNDNKGENYGSIY"
     gene            complement(2265..3215)
                     /locus_tag="RFE25_002478"
     CDS             complement(2265..3215)
                     /locus_tag="RFE25_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDU2817512.1"
                     /translation="MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLP
                     RLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPV
                     FSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTI
                     ANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLIT
                     YIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVIGGQIMVM
                     ADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH"
     gene            complement(3364..4251)
                     /locus_tag="RFE25_002479"
     CDS             complement(3364..4251)
                     /locus_tag="RFE25_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDU2817513.1"
                     /translation="MKKSLIAFILIFMLVLSGCGMKDNDKQGSDDNGSSKSPYHRIVS
                     LMPSNTEILYELGLGKYIVGVSTVDDYPKDVKEGKKQFDALNLNKEELLKAKPDLILA
                     HESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEET
                     KDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGW
                     NPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSR
                     PGPRIDEGLKELRDAIYRK"
     gene            complement(4503..5138)
                     /locus_tag="RFE25_002480"
     CDS             complement(4503..5138)
                     /locus_tag="RFE25_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III domain-containing protein"
                     /protein_id="HDU2817514.1"
                     /translation="MLGTDELYKLLYRHMGPQNWWPADNDIELMLGAILVQNTRWRNA
                     EIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKTLTIKTLLTWLARHHFNYQ
                     EINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKN
                     YDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK"
     gene            complement(5408..7069)
                     /locus_tag="RFE25_002481"
     CDS             complement(5408..7069)
                     /locus_tag="RFE25_002481"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDU2817515.1"
                     /translation="MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDY
                     ATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAII
                     PEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYN
                     VTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHP
                     EIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAK
                     MKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILI
                     DLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLR
                     EIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAK
                     EQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLAAHFH
                     KFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM"
     gene            complement(7066..7482)
                     /locus_tag="RFE25_002482"
     CDS             complement(7066..7482)
                     /locus_tag="RFE25_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDU2817516.1"
                     /translation="MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQI
                     EDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILH
                     FVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE"
     gene            complement(7575..7683)
                     /locus_tag="RFE25_002483"
                     /pseudo
     CDS             complement(7575..7683)
                     /locus_tag="RFE25_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499172.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7758..8768)
                     /gene="adhP"
                     /locus_tag="RFE25_002484"
     CDS             complement(7758..8768)
                     /gene="adhP"
                     /locus_tag="RFE25_002484"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HDU2817517.1"
                     /translation="MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVK
                     NADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETL
                     CRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVK
                     PGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDP
                     VAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVL
                     DGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVI
                     KF"
BASE COUNT         2814 a         1738 c         1145 g         3301 t
ORIGIN      
        1 tgtaataaaa taaccgacaa gtattgcgat ttaacttgtc ggttaagcac gattaattta
       61 attattattt ttccaaatca atacgatata attttatgtt tttatctttt ggtgctgagg
      121 caaattgata agtcgttttg cctttttcaa tatatccaaa attaccagca actttgctat
      181 attccgtatg tgttactgct ttgccaacat aatttttaac agcttgatat gttggaccat
      241 tagcatcatt atacatcatt gaaatatgag ttactttacc attgtttttc ttaccatcag
      301 tagttactaa taacatacct tttttagtat ggaattcgta ataatgttca gttccatctt
      361 cattgtaaga atacatagga tttttgtact tagttaaaac atctttaata gattcgccaa
      421 ttttcacatt ttctaatgac tgatcaccct taattaattg tttaacagta tcaatagagt
      481 tgccacttgc tgcttcggca ctagtgttca ctaagcctac tcccattaca acagaacatg
      541 caattatact tgccgttagt agctttttca taagcactct ctccttttat ttatatcgtc
      601 ttgtgctcac aaccattata caacaatcat ttctaaaaca acagtcatat tacaattata
      661 ttacaaataa taattactac ttttatattt cacttatcac taaaaattaa acatgctttt
      721 catcgtgatg tttgttgata aatgaagctg tatcttcgac gaatctttct tgctcttcaa
      781 caaatgggaa tgcacttgat tcttgatata cttcaaagtc cgcattttgg attaaatcag
      841 ctacttcttt agcttccaat cttgttgttc tttcaccgaa ttctcctgca ataatttttg
      901 tcggtactac gacatttcta taagtttgag aaatatcagc gtttttgaat acctctttaa
      961 ctgcttgaat ttcttcttta gttgatattt catttgtatc tacgacatgt ttaaggaatc
     1021 gattcatttt tctcggacga taatacttac gcttatttaa aaatttatct tgtttttcag
     1081 gatcccagtt tcgaataata tgggcatatt ttctaaataa acgttcttcc ggtaattcac
     1141 cttcaataga tgttggattt accaacataa gtgatgatgt aaattcagga taacgtactg
     1201 aaatatccgc accaatgatt ccacccattt catggcatac aaatgcaact tcttcaatgt
     1261 ataaatattt aagtaattca acaatgtcat cagaaaaatc ttttatttca atgtgacgag
     1321 gtttatcaga atagccatgt ccacgtaaat caattaacac aacttgaaat gattttgcta
     1381 attgtgctgc taatttatta aacacagaat aattatcaag tacagtatga atcaatacga
     1441 taggatagcc ttcacctaat gtactgtaat gtatcgatgt tccatctttt ctagtaaata
     1501 gatccataat tttctccttt attatcattt tttattggta aaatggttaa taattcttcc
     1561 actgttgtaa ttgtaaaatc aacttcttct tcgagtggtt caatttcagc atcttcttgt
     1621 ttataccata cactaaccat gcccatagct cgtgctggag ctacatcatt taacgcatca
     1681 tcgccaacat acataatttg ctcaggtaat acccctagtt gatcaatcat atcttcaaaa
     1741 attttaggat gtggtttacg aaaaccaact gtttctgatg ttgataaata attaataaca
     1801 tgcatcaaac caagtgaatg taatcgaaat tgtttaatct tagatttacc atttgcgata
     1861 acaccaattt gaaagccttt ttgcgatagc ttttctagtg tatacaaagt atcgtaataa
     1921 ggaaatacat aacgataaaa atgcatttca aaatcattaa ataagtcttt ccaagttaac
     1981 ctatctacat ggaaacgttt aatgatttct ttatataaat caggtttatc attatcttca
     2041 tcgtcatcta gctcaataaa tgctttttta aaatctgcca gttgaacatg aattaagtag
     2101 tcatgaaatc gttcatattg ctcttcgata aatttctctc gagatttaac tctgtccaac
     2161 aacgtacctt ctaaatcaaa tacaactgct ttaatttgat tcaaatccat cgcttatgcc
     2221 ctctttatgt ttatagttat ttttatttta gcaaatgtca tgtgctagtg taaccgtttc
     2281 gactgagata ttagcatgta aaataacact ggtataccaa ttaatgcaat aataatgctt
     2341 gccggtattt gtactggtga cagtatatgg ctaccaataa aatctgccat aaccattatt
     2401 tgtcctccaa ttacaatatt caaagccaat tgtcttccta atgattgttt ccactgccat
     2461 tttctaatga gttgtggtat caccatacca atgaatccaa tgatgccaac atatgcgaca
     2521 tttatcgccg ttatcataga agctatacat aacgcgatat atgtaatcaa ttgaacattt
     2581 aagcctagtg actgactttt tagttctcct aattgcaata actttagttg attaagaatg
     2641 ataaatatac caaacagtgc aatgataaat gtgattgcta ttatggatac atttgagtat
     2701 tctgcatcac caaagccacc aaacaaataa ttggcaattg tatttaattt gcgaggtttt
     2761 aataaaatca aaaaatatag aagtgaattg aataatgcac caatcattaa accacttaat
     2821 attaagattc taactggata gccttggctc aataccgacg taatgactaa tacagttatt
     2881 aatgttatca aactaaatgt tattgaaaat acaggaatcc ataacgttgt taaacctaaa
     2941 aataatgcta atcctgaacc aaatgtagca ccgcttgcca atcctaatgt aaagctatct
     3001 gccaatgcat tatttaaaac tgtttgaaat ataagacctg caactgttaa tatcatacct
     3061 gtcaacaatg cttctaataa tctcggtaat ctaacattga ttaaaataga ctggttaaat
     3121 acatcattga tatcccccaa ctgccaaaat agatatatgc tagttgttat aatcaatatg
     3181 actatccagc tcaataatac tttattaaat gtcatagcat tctcttttct ttcatcgata
     3241 attacattca ttatagcaat cacatactcg cgttgctatc attcactaaa tatattttaa
     3301 aaacccctta tctcaaacat gtattttttt acatgtagca ataaggggca taattagaat
     3361 ggtttatttt ctataaattg catctcttaa ttcttttaat ccttcatcaa tacgtggacc
     3421 tggtcttgat acttcatcac catttacaac ttcaatacgt gtattcttga cagcattaat
     3481 tttattgaat ccaccccttt ttttgatgat atccatataa tctgatcttg tcttagcttc
     3541 cgtcgaaatt aatatatctg ggttcttttt aataatactt tccttcgtta cagggttcca
     3601 accattaatg tcactataaa cattttgggc ttctaatttt tctaacatat cattaaaaaa
     3661 tgtatgcttc cctgctgtat atatttcagg ctttgatgaa acctcaataa atacttttga
     3721 ttttttatga tgagcaggaa ttgaatctat gactttatcg atattatctt tagtttcctc
     3781 aacaagttgt tcagcctgct tatcatgatg cgttaatttc ccaatttgct taaatgtgtt
     3841 gtatgtttca tcaattgatt gtgcatcttt aacatacact actttgatgc cttgtttctc
     3901 taatgatgac aatactttat tagcagttgc cttttgcgac tcatgcgcaa gaattagatc
     3961 tggctttgcc tttaaaagtt cctctttatt tagattcaaa gcatcaaatt gtttcttacc
     4021 ctctttcaca tcttttggat aatcatcaac cgttgaaaca ccaactatgt atttacctaa
     4081 tcctaattca tataaaattt cagtattact aggcattaac gaaacaattc tatggtacgg
     4141 cgatttagac gagccattat catcgctacc ttgtttatca ttatctttca taccacagcc
     4201 actcaggaca agcataaaaa tcaaaataaa agcaattaac gatttcttca cattatcaca
     4261 tctccttttt aatcccactt ttcgctttag cgattagagg gatttatgca gttgtgcctt
     4321 agcatccaac tgcgttcctc ttcaccttta gtgattagag gcttttatgc agttgctgca
     4381 caaacaaaca actgtttttt tctttatatg cttctattta ttatataagt ccacatacta
     4441 aaagaaaata gtaaattatt ttttatattt catataaact catctatcta acttcacagc
     4501 gtttactttt taaagtaagg ttctaaaaaa tcataattct ttatatcttt gtctctaaag
     4561 taatgtttac caaatacatc taacagagca tgaaattcat tagcatcttg atttgtaaaa
     4621 tgatttggta atgtgactac tttttttaat tgatcataat ttttagtgtt ttcatatcct
     4681 aatttatcat atatttttct tgtatagcta tctggaataa attcaatacg tccgaatata
     4741 taaacaagta agacatctgc tgtttcactt ccaatacctt tcaaagataa taattctttt
     4801 cttaatccac ctttatatcg ctcattaatc tcttgataat tgaaatgatg tcgtgctaac
     4861 catgttaata atgttttaat cgtcagtgtt ttacttttat aaaagccact tgaatgtatc
     4921 aatgattgta acgtttcaat aggtagttct aatatatgat tgggattaaa atgcgtatgt
     4981 tctttaatct gattcaatgc aatttctgca tttcgccatc tagtattttg aactaaaatt
     5041 gcacctaaca tcagttcaat gtcattatca gcaggccacc aattttgcgg tcccatatgc
     5101 ctatataaca atttatacaa ttcatcagtt cctaacattt acaccctcct tttagagccc
     5161 ctaattaata aattaattag gggctcttat gcagttgctg cgcaagcaag ccaactgtat
     5221 tcctttactc cccttgagct ttagcgattt aggctctctt atgcagttgt gcagtagcat
     5281 ccaactgcgt ccctcttaac cttattcaca tactaagcat tccccaatat gtcacatacc
     5341 taattaaaaa cactccaaca caaagtatct ttcgagaaac tctacgttgg agtgtatata
     5401 aatgttctta cattgattca ggtgcgctta caccgaccat tgccaatgca tttttcaatg
     5461 taattctgac cgcttcaatc atagcaacat gtgcttttgt tttttcaata tcatctgtta
     5521 acactttttc agcattatag aatttatgga aatgagcagc caagtcttga atatagttag
     5581 taattctatg tgctgatcta tgctcagcag cactttcaat tgtaggttcg aaatcagcta
     5641 cttttttcaa caattcaatc gctttttcat ttgtaatcgt tgtaaaatca ttcgcagcag
     5701 tcacttcaat accttgctct ttcgcttgtt ttaaaattga acaaatacgc gcatgtgcat
     5761 attgagcata gtaaactgga ttgtcttgag attgctcttt cgctaattcc atatcaaaat
     5821 caaagtgact atcaggacta cgcatagtta agaaataacg tgcagcgtca acgccaactt
     5881 cgtccataat ttctcttaat gtaatcgcat taccagtacg tttactcatc ttcacttctt
     5941 taccattttc cattaaacga accatttgca tgatttgaat ttctaaacga ttactatcta
     6001 caccaaacgt ttcaagagat gctttcaaac gattaatata accatgatga tcagcaccaa
     6061 ataaatcgat taaaatgtca ttaccacgtt taactttatc gaagtggtac gcaatatctg
     6121 gtaagaaata cgtatatgta ccgtcatttt taattaatac tctgtctttg tcgtctttaa
     6181 aatcagttgt acgtaaccat gtagcgccat cagcttcata cgtataacct aattctttca
     6241 tttttgctaa aacttcaaga atttcgcctt tttcatataa agatgtttca ctaaaccaat
     6301 tatcaaaatg cgtattgaac tctgctaaat catttttcaa tttagccatt tcgtattcta
     6361 cgcctaattt tctaaattct ttcaaacgtg cttcttcaga ataatcttta atttcagggt
     6421 gtttctctgc taaatcttta cctatttcaa taatatcttt tccattatag ccatcttctg
     6481 gcattgaata actattgtca cctaaagctt caaagaaacg tgtttcaatc gaacgcgcta
     6541 agttagtaat ttgattacca gcatcattaa tataatattc acgtgttaca ttatagccag
     6601 ctgcagttaa aatattagct aaagcatcac caactgctgc atttctagca tgaccaatat
     6661 gtaaatctcc tgtagggtta gctgaaacat actcaagcaa tacattttga ccttttgatt
     6721 catttacatg tccaaattga tcaccttttt caattgcttc aggaataatt gctgttaaat
     6781 actgattatc taagtaaaaa ttaatgaatc ctggaccagc aatgtcaatt tgttttacat
     6841 gtgctttttc agtatctaag ttatcaacaa tcgcttgagc aatttcacga ggattacgct
     6901 ttgcaatctt agtcagtacc atcgcaatat tagtagcata atctccattt tttgtatctt
     6961 taggaacttc aattttaata tcaggaatct catctgctaa tcctgctttg ttaatacttg
     7021 ctgcaatttc ttctactaat gtttgtttca cttgatcaat aatattcatt cgcctatctc
     7081 cttatagtta atttcatatt gataagaacc cattttttca ttatcttgat ataattcata
     7141 atgaatcttt agcttgccac cgtctccact tacgaaatgt aaaatgcgta atgttttaac
     7201 ttctagtgga attcgtccag ccgatatatc gtaaaaagtt gttgtcgttt gtccttcaac
     7261 aaaatgcaaa ttcatattaa tgtcgccttt acgaatcaac ttaacgctat catcatccac
     7321 ttttattgta acattaactg ttgcatcctc aatttgttct acataccgaa taaagttaga
     7381 ttgcctttgt tgccaagttc cttcagtagt aaattcaaat ttttcttttt cgttgtgctg
     7441 tttcaacact tgctttgttt gaatacttac ttttttatcc aatttactac tcaccttaat
     7501 cttcgcataa tagaaatatt atagcataaa ataaggtcat cttgttatgc cttcttaaag
     7561 ctaaataggt tcaattaatt aacaattcca tacttaatca acgcttcata tatgtaagcc
     7621 attttataaa atacaaacaa cacctcaaaa ccaaaaaaac acgagatttt cactatcttt
     7681 catgaaaacc tcgtgtttga ttataatgat agtgttcaga gcactacctt ctttatctat
     7741 atagtcagtt gatattttta aaatttaata accattctac cagttatagt accattttcc
     7801 atttcttcaa aaatatcatt gatttcttct aattttctta attgaacttt aggtgttact
     7861 ttattttcag cagcaaattc aaacgcttca cgtaagtctt gtcttgtacc aacaagtgaa
     7921 cctactactt caataccgtc aagcactaat cttgggatat ctaagttcat tttatcaaca
     7981 ggtaaaccaa cggcaacaac tcttgcacca gcttttacaa catcaaccgc ttggttaaat
     8041 ggcgtcttag caactgaagt taccactgtt gcatctaatc ctttgttatc agttaatttc
     8101 ataacttctg caactggatc aacatcttta gaattaataa tagcatctgc acctaattct
     8161 ttcgcgaatg ctaatttatc atcattaatg tcgaaggcaa caattttagc ccccataacg
     8221 tttttagcat attgtaaagc taggttacct aaaccaccta taccaaaaac acctaaccat
     8281 tgaccaggtt ttacattact tacttttaca gctttataag ttgtcacacc tgcgcatgta
     8341 atagaagacg ctgctgctgg atctaatttt tcaggtactt tcacagcata gtctgcagta
     8401 acaataactt gttcagccat tgcaccatct actgtataac cagcattttt cacactacgg
     8461 caaagtgttt cacgacctgt tgtacaatat tcacatcttc cacagctttc gaacatccaa
     8521 gcgatagaca cacggtctcc aatttttaat gattctacat cttctgcaac ttcgatgact
     8581 ttaccaatac cttcatgacc taaagtaacg cctgtaacat caccaaaatc agcattctta
     8641 acatgtaaat cggtatgaca aacaccacaa tattccgttt gtaccaatgc ttcaccaggt
     8701 tttaaagctc ttaacttttt gtcctcaata cttactttgt gatctttcgt tacaactgct
     8761 gctctcataa taatgtcctc cttatagtca ctccagtatg tatgatatta attggcgatt
     8821 actttcaaaa atgaaaacga ataattatag atgtaatttt tatttgtaat agacgccaga
     8881 ttaaaacata ctactgtgac tttgttttta gttagatatc aaccgttaac ttttaacgtt
     8941 tccctagtta atatgttaaa agaaatgaca taatcgatat gctaacgtgt aattttta
//
LOCUS       DAPDIM010000087         8877 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000087 DAPDIM010000000
VERSION     DAPDIM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8877
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.087"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(561..704)
                     /locus_tag="RFE25_002485"
     CDS             complement(561..704)
                     /locus_tag="RFE25_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001094921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDU2817518.1"
                     /translation="MNTLVNMFFDFIIKLAKAIGIVGGVNACSSLFDEPKVPAELTNL
                     YDK"
     gene            complement(707..1270)
                     /locus_tag="RFE25_002486"
     CDS             complement(707..1270)
                     /locus_tag="RFE25_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="HDU2817519.1"
                     /translation="MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKIL
                     VTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINI
                     DINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIH
                     PFYAQFMLLGILVESITLLPIFFPKED"
     gene            1506..1640
                     /locus_tag="RFE25_002487"
     CDS             1506..1640
                     /locus_tag="RFE25_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lysin family phenol-soluble modulin"
                     /protein_id="HDU2817520.1"
                     /translation="MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
                     "
     gene            complement(2240..3025)
                     /locus_tag="RFE25_002488"
     CDS             complement(2240..3025)
                     /locus_tag="RFE25_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen family hydrolase"
                     /protein_id="HDU2817521.1"
                     /translation="MKVQIYQLPIIFGDSSKNETQITQWFEKNMNAEVDVVVLPEMWN
                     NGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNYQIFNTAFSVNKSG
                     QLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPAR
                     SGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINP
                     NGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK"
     gene            complement(3386..4012)
                     /locus_tag="RFE25_002489"
     CDS             complement(3386..4012)
                     /locus_tag="RFE25_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDU2817522.1"
                     /translation="MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHA
                     VKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSY
                     GTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYN
                     PLVDEMTSKEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK"
     gene            4209..5417
                     /locus_tag="RFE25_002490"
     CDS             4209..5417
                     /locus_tag="RFE25_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817523.1"
                     /translation="MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTN
                     LNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPST
                     DSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNLDPKPDPDNPKPKPDPDKPK
                     PNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQG
                     NSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFS
                     GNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPD
                     SKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNK
                     KKNKNESQRR"
     gene            complement(5442..6185)
                     /locus_tag="RFE25_002491"
     CDS             complement(5442..6185)
                     /locus_tag="RFE25_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDU2817524.1"
                     /translation="MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIY
                     IQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIV
                     LTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGN
                     RIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNG
                     FVVIFQLLNPEALKKATEQANFIYHIFIP"
     gene            6360..6644
                     /gene="groES"
                     /locus_tag="RFE25_002492"
     CDS             6360..6644
                     /gene="groES"
                     /locus_tag="RFE25_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDU2817525.1"
                     /translation="MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGT
                     GRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE"
     gene            6720..8336
                     /gene="groL"
                     /locus_tag="RFE25_002493"
     CDS             6720..8336
                     /gene="groL"
                     /locus_tag="RFE25_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500736.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDU2817526.1"
                     /translation="MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFT
                     APLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEG
                     LKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYI
                     SEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYI
                     LVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKA
                     PGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGD
                     GDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKL
                     RIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQ
                     IAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVA
                     AMFLTTEAVVASIPEKNNDQPNMGGMPGMM"
BASE COUNT         3272 a         1310 c         1464 g         2831 t
ORIGIN      
        1 aattaagcta tcaccgtttg aacttgtatt tgtagaataa atataaaaaa atgcaaatgt
       61 tgcaaataat acgaatgaaa ttataatcat ataagtttta tttaaagata agtatgattt
      121 tttaaatttc tttagagata ttcttaccaa atatgtcgct aataatgaaa ctgatgaaaa
      181 agaaagtata tataatggta agagtattgc aggatcagta gtgtattttc ttaaagttaa
      241 aaacaaacct actgttgcaa aattactcaa atacattatg atcatggtca ctaaaattgt
      301 tactattgca tagtacttta atttaaagaa taaaaatatg atagatgaaa aagttggaat
      361 caatacggct ctacttccat agaagtaata caaaaacatg gttggaatta taattccaac
      421 tataataaaa taatccctta aattaaattt aacaaaggaa atgaatttgg ctactgtaaa
      481 aagtattact aattgaaaag tggccatagc taagttgttt attgtttcca tatgctacac
      541 actttctaaa ataactttta ctatttgtcg tataaattcg ttaattcagc gggtacttta
      601 ggttcatcaa ataaactgct gcaagcgttt acgccaccga caattccgat tgctttagct
      661 aatttaatta taaaatcaaa aaacatatta acaagtgtat tcatgattaa tcctccttag
      721 ggaaaaaaat aggtaataat gtaatagatt ccactaaaat tcctaataac ataaattgag
      781 cataaaatgg atgtattatt aaggatagaa tcaaaactaa taaatacata attatagata
      841 aatacttttt acgttttact aattttattg gtataggttg ctttttcgtt gctgcaggtg
      901 cataaataac aacggaaatc aatcctataa tagataaggc cagtaaataa gtaaaattaa
      961 tgtctatatt aattagaaaa taaggtacaa atacaaatgt taaaatactt tgtatgtaac
     1021 aaagtatcga agactttgca tgagcaccat gtgcattata gcgtattaac atataggata
     1081 agtgtgtaac taaggtaaac aaaaatacac ttaagaatat agaaatacta tatgttacaa
     1141 gtattttaaa aaaattacca actataattt gcatccctaa acgtacttgc aaaaattgaa
     1201 tatgatctaa gttatttctc ttttgaagat acgtggcaaa ctggtcaatt ttgttatcaa
     1261 aataattcaa ttttacacca ctctcctcac tgttattata cgatttagta caatctttta
     1321 tcattatatt gcctaactgt aggaaataaa tacttaactg ttaaatgtaa tttgtattta
     1381 atattttaac ataaaaaaat ttacagttaa gaataaaaaa cgactagtta agaaaaattg
     1441 gaaaataaat gcttttagca tgttttaata taactagatc acagagatgt gatggaaaat
     1501 agttgatgag ttgtttaatt ttaagaattt ttatcttaat taaggaagga gtgatttcaa
     1561 tggcacaaga tatcatttca acaatcggtg acttagtaaa atggattatc gacacagtga
     1621 acaaattcac taaaaaataa gatgaataat taattacttt cattgtaaat ttgttatctt
     1681 cgtatagtac taaaagtatg agttattaag ccatcccaac ttaataacca tgtaaaatta
     1741 gcaagtgagt aacatttgct agtagagtta gtttccttgg actcagtgct atgtattttt
     1801 cttaattatc attacagata attatttcta gcatgtaagc tatcgtaaac aacatcgatt
     1861 tatcattatt tgataaataa aatttttttc ataattaata acatccccaa aaatagattg
     1921 aaaaaataac tgtaaaacat tcccttaata ataagtatgg tcgtgagccc ctcccaagct
     1981 cgcggccttt tttattgtaa taaagaaggg gagagttaat cctcattatg agacccaccg
     2041 ttaaaatata tgaataagtc taatgttgga aaaggtcaaa aaattaatca atttaattaa
     2101 gaaaatcatt catttgcaaa gggcgaaatg gattcttact gagttatcta ttataaaaaa
     2161 ataaacatag acttatgaaa aatctctcat aaatctatgt ttagtcatga catgtgttaa
     2221 atattatttc gggcgcttct tatttataca aatctaattt aatactttta aatacaggta
     2281 tattttcgcg ttgctgttct acttcattta agtttaaatc tacagtcaaa atatctgcgg
     2341 attcatttaa ttctccaact aaatctccat ttgggtttat aactatcgaa tgaccagcat
     2401 attctgtgtt accatcgaat ccagtgctat tagttccaat gacaaacata ttattttcaa
     2461 ttgcacgtgc ctttagtaat gaatgccaat gttgaagacg tgacataggc cattgcgcca
     2521 cataaaatgc aattttagca ccactacgag caggatatct taataattct ggaaaacgta
     2581 aatcataaca gataagttgg gtcacataag taccgtcaga caattgaaag ggttcagcta
     2641 cgttttcgcc agcggttaaa aattcatgct ctcttaacat aggaactaaa tgaactttgt
     2701 cgtattcatt aatcagctgg ccacttttat tcacactaaa agctgtatta aatatttgat
     2761 agtttctaat gttagaaact gacccagcta cgatatcgac tttatatttt tcagctaaat
     2821 gtttaataaa tgaaaaactt tgtcctagat tattatctgc tttttcattt aaatgctcta
     2881 aatcatagcc attattccac atttcaggta aaacgactac atctacttca gcattcatat
     2941 ttttttcgaa ccattgcgtt atttgagttt catttttaga actatctcca aaaataatcg
     3001 gtaattgata aatttggact ttcataacat cgcatccttg atagatctta tatataactt
     3061 actaaaagtt atgttgaaac gcaaaaaacg agcccaagac ataaaatcaa agtcctaggc
     3121 tctacaatgt tatattgaca gtagttgatg gggccccaac atagagaaat tggaacacca
     3181 atttctacag acaatgcaag ttggggtggg ctctaacata aagaaatact ttttctttag
     3241 aaattagtat ttcttataca tgagttttac tcatgtattc ctattcttaa gtgcacatta
     3301 gcagcggcta atgtgtaaga actactacat aatgaataac taatgattct ttatcatttc
     3361 tgtcccattc ttaacaatat attgattatt tttttattac gaaacgatct tccactggat
     3421 taaatgtttt ttcgccagca gcttcacgaa tatcaccaaa tggcatttga gcaataagtt
     3481 tccaactttt aggaatatta aattcttttg aagtcatctc atcgacaagt ggattatagt
     3541 gttgtaatga agcacctatg cctttagtag ctaatgcagt ccaaattgca aattgatgca
     3601 tggcatttgt ttgagttgac catattgcaa aattatcata gtagtttggc atttgttctt
     3661 gtaaaccact tacaacatct tgatcttcat aaaacaaaat tgtaccgtat gaatgtttga
     3721 agttatcaat tttttgttca gttggctcga aatcacgatt ctctcccatg acttctttta
     3781 aaattgcttt tgtgttatcc caaaatttat tattgttgtc atttaacaag agaacaattc
     3841 tagttgattg agaattaaat gatgaaggaa catgtttaac tgcatgtgca atcattgatt
     3901 ctaattcgtc atcgctaatt gatatcgaat ctttcaaatt atatattgaa cgtctttctt
     3961 ccattgcatt gtcaaaagtc attgcttttt tatctttttt aaataagccc ataattattg
     4021 ctccttcttt agtaaagaat acttaataga ctaagtataa aatttatact cggacttgta
     4081 aagtaatatt tacgaaaatt tcaagaatat taatattcat tttcaaattc caaatataaa
     4141 tgcattttca acgcatattt attatactta gattaatact tacatgaaaa agggaggtgt
     4201 ctcgtgaaat gtcatatcat tggtttaaga aaatgttact ttcaacaagt attttaattt
     4261 taagtagtag tagtttaggg cttgcaacgc acacagttga agcaaaggat aacttaaatg
     4321 gagaaaaacc aactactaat ttgaatcata atataacttc accatcagta aatagtgaaa
     4381 tgaataataa tgagactggg acacctcacg aatcaaatca aacgggtaat gaaggaacag
     4441 gttcgaatag tcgtgatgct aatcctgatt cgaataatgt gaagccagac tcaaacaacc
     4501 aaaacccaag tacagattca aaaccagacc caaataacca aaacccaagt ccgaatccaa
     4561 aaccagatcc agataacccg aaaccaaaac cggatccaaa accagaccca gataaaccaa
     4621 agccaaatct ggatccaaaa ccagatccag ataacccgaa accaaaacca gatccagata
     4681 aaccaaagcc aaatccgaat ccaaaaccag accctaataa gccaaatcct aacccgtcac
     4741 cagatcccga tcaacctggg gattcaaatc attctggtgg ctcgaaaaat gggggaacat
     4801 ggaacccaaa tgcttcagat ggatctaatc aaggtcaatg gcaaccaaat gggaatcaag
     4861 gaaactcaca aaatcctact ggtaatgatt ttgtatccca acgattttta gccttggcaa
     4921 atggggctta caagtataat ccgtatattt taaatcaaat taataagttg ggcaaagatt
     4981 atggagaagt tactgatgaa gacatttata atattattcg aaaacaaaat ttcagcggaa
     5041 atgcatattt aaatggatta caacagcaat cgaattactt tagattccaa tatttcaatc
     5101 cattgaaatc agaaaggtac tatcgtaatt tagatgaaca agtactcgca ttaattactg
     5161 gtgaaattgg atcaatgcca gatttgaaaa agcccgaaga taagccggat tcaaaacaac
     5221 gctcatttga accgcatgaa aaagacgatt ttacagtagt taaaaaacaa gaagataata
     5281 agaaaagtgc gtcaactgca tatagtaaaa gttggctagc aattgtatgt tctatgatgg
     5341 tggtattttc aatcatgcta ttcttatttg taaagcgaaa taaaaagaaa aataaaaacg
     5401 aatcacagcg acgataatcc gtgtgtgatt cgttttttat attatggaat aaaaatgtga
     5461 tatataaaat tcgcttgttc cgtggctttt ttcaaagctt caggattaag taattggaat
     5521 ataacgacaa atccgttttg taacatatgg ataataattg gaacagcaag ccgttttgtc
     5581 catacatatg ctaatgaaaa aatgacgccc ataccaaaat aaactggaat aaatttgaaa
     5641 tcattatgtg ctaatgcaaa tattaatgaa cttactgttg tagcaataat aaatgctacg
     5701 atacgattac ctttaatcgc attaaataat tctccaaaga ttacttttct gaatacgtat
     5761 tcttctaata aaggaccgat aatagataca aagaagataa atataggtat ttttcgagca
     5821 ataataatta gcttttctgt attaggactt acttgttgtc caccataaat ttgcgttaat
     5881 acaatgctca ctaccatttg ataaatcatt accaatgcaa atccaagcaa tgcccatgga
     5941 atgatatatt ttttaggttc tttaacttct aattctaatt ttgttggatt tttaattttt
     6001 aaattaatta aaataatcgt cgtggcggcg attaaaaata gaacaagttg tatgtaaatg
     6061 actgctttag tcagttctat gccactatat tgtacaaatg gtaatttttt tacaatgaga
     6121 agcggtaaaa attgagacaa tatataaata ataacagtta gcaatgatgc ccataatctt
     6181 gtcataattt tcctccaaat atttgtttat aatttatttt atcgtaaata acttgaagtt
     6241 acaaaactta attaaaaggt tatgacttga aattttgacc aaatttgatt attataaatg
     6301 tatgttagca ctctttaatg ttaagtgcta aactttaggt tttttaagga ggaacaatca
     6361 tgctaaaacc aattggaaat cgtgtgatta ttgagaaaaa agaacaagaa caaacaacta
     6421 aaagtggtat tgttttaact gatagtgcta aagaaaaatc aaacgaaggc gttatcgttg
     6481 cagtaggaac tggacgtcta ttaaatgatg gtacaagagt gactcctgaa gtgaaagaag
     6541 gggaccgtgt cgtgttccaa caatatgctg gtacagaagt taaacgagat aatgaaacat
     6601 atctagtatt aaatgaagaa gatattttag cggtaattga ataatataaa attaaattca
     6661 tagataaatt gtaaagaacg aaaatgaaat atgactaaac aaatggaggt ttatcattta
     6721 tggttaaaca attgaaattc tctgaagatg cacgtcaagc aatgttacgt ggtgtagacc
     6781 aattagcaaa tgcagttaaa gtaacgattg gtcctaaagg acgtaatgtt gtattagata
     6841 aagagtttac agcaccttta attacgaacg atggtgtaac gattgctaaa gaaatcgaat
     6901 tagaagatcc atatgaaaat atgggggcta aactagttca agaagttgca aataagacaa
     6961 atgaaattgc tggtgacggt acgacaactg caacagtatt agctcaagca atgattcaag
     7021 aaggcttgaa aaatgttaca agtggtgcga acccagttgg tttacgtcaa ggtatcgaca
     7081 aagcagttaa agttgctgta gaagcattac atgaaaattc tcaaaaagtt gaaaataaaa
     7141 atgaaatagc gcaagtaggt gcgatttcag cagcagatga agaaattgga cgttatattt
     7201 ctgaagctat ggaaaaagta ggtaacgatg gtgtcattac aattgaagaa tcaaatggac
     7261 taaacactga actagaagtg gttgaaggta tgcaatttga tcgtggttat caatcaccat
     7321 atatggttac tgattcagat aaaatggttg ctgaattaga acgcccatac attttagtaa
     7381 cagataagaa aatctcgtct ttccaagata tcttaccttt attagaacaa gtggttcaat
     7441 ctaatcgtcc aatcttaatt gtagctgatg aagttgaagg cgatgcatta acaaatatcg
     7501 tgctaaaccg aatgcgtggc acatttacag ctgttgcagt aaaggcgcct ggtttcggtg
     7561 atcgtcgtaa agcaatgtta gaagatttag ctattttaac tggtgcgcaa gtgattactg
     7621 atgatttagg cttagattta aaagatgcat caattgatat gttaggtact gcaagtaaag
     7681 tagaagtaac taaagataat accactgttg ttgatggtga cggtgacgaa aacagcattg
     7741 atgcacgtgt aagccaattg aaatctcaaa ttgaagaaac tgaatctgac tttgatcgtg
     7801 aaaaattaca agagcgctta gctaaattag caggtggtgt tgcagttatt aaagtaggtg
     7861 cagcaagtga aacagagctt aaagaacgta aattacgtat tgaagatgca ttaaattcta
     7921 cacgtgcagc agttgaagaa ggtattgttg caggtggtgg tactgcatta gtaaatgttt
     7981 accaaaaagt aagtgaaatt gaagcagaag gtgacattga aacaggtgta aatattgtac
     8041 ttaaagcact aactgcacca gttcgtcaaa ttgctgaaaa tgcaggatta gaaggttctg
     8101 ttattgtaga acgtttgaaa aacgcagagc cgggtgttgg ttttaacgct gctacaaacg
     8161 agtgggttaa tatgttagaa gcaggtatcg ttgatccaac taaagtaaca cgctcagcat
     8221 tacaacatgc tgcaagtgtt gcagcaatgt tcttaacgac tgaagcggtt gtagcatcaa
     8281 ttccagaaaa aaataatgac caacctaaca tgggtggcat gccgggaatg atgtaaaaca
     8341 gtttctagtt ttgactaact agaacattcc atgatagacg agtatgattc gttccaaata
     8401 aatattagag cgtatgaaaa tattttaatt taagacacct tccattagtt gactaaactt
     8461 atgagaggtg tcttttttat gtgctaattt gtaattgaga ttcataatgg tatttaaatc
     8521 attatggtgc gggagttatg gtattgccat aatatgagag tgcatccact tctataagta
     8581 atgcatattg cgagtgcagg aatgaatgag tgcttgatta aaatccttat gggtggttga
     8641 cataattaaa agaaaccaca tttaaaattt cttaatcaca agcggttaac taggtatagt
     8701 ttagttttga gtaaatcttt ttaaaggtgt acttgtgcat tttacttaat taaagagata
     8761 agacatttaa tgggcctaaa ataaataaaa aacaaaaaac tacctgttta ggtagttttt
     8821 taaatgtaat agattaaaac actagttcat ttcttgttaa agatggatag ttatttt
//
LOCUS       DAPDIM010000088         8733 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000088 DAPDIM010000000
VERSION     DAPDIM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8733
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.088"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            131..2281
                     /locus_tag="RFE25_002494"
     CDS             131..2281
                     /locus_tag="RFE25_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817527.1"
                     /translation="MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKII
                     EDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLL
                     LKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYI
                     YQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDST
                     ISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKE
                     IILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKN
                     SQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINDIETTYFVEEAFMSVF
                     RQISPNELSNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPS
                     VFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQ
                     EKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHHTFNAMHL
                     YDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSN
                     FEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNY
                     LKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK"
     gene            2427..2786
                     /gene="sarX"
                     /locus_tag="RFE25_002495"
     CDS             2427..2786
                     /gene="sarX"
                     /locus_tag="RFE25_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarX"
                     /protein_id="HDU2817528.1"
                     /translation="MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHC
                     KDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDD
                     ISKFNALFEDVEQFLNI"
     gene            2976..3692
                     /locus_tag="RFE25_002496"
     CDS             2976..3692
                     /locus_tag="RFE25_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDU2817529.1"
                     /translation="MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESN
                     QALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNN
                     VNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVND
                     VIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKL
                     IDALEDLEDVQNVFHNVDLK"
     gene            3692..4165
                     /locus_tag="RFE25_002497"
     CDS             3692..4165
                     /locus_tag="RFE25_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDU2817530.1"
                     /translation="MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFL
                     LTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYVVPK
                     GTIFASSIEISNTYSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK"
     gene            4257..4373
                     /locus_tag="RFE25_002498"
     CDS             4257..4373
                     /locus_tag="RFE25_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817531.1"
                     /translation="MLQLFLMKIALNDFENDKSVLFIFLKNHFYEEMCVLSN"
     gene            4518..5162
                     /locus_tag="RFE25_002499"
     CDS             4518..5162
                     /locus_tag="RFE25_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDU2817532.1"
                     /translation="MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDP
                     LEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGN
                     ARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDF
                     KGFQKKIMYCFNKINAKAQKNHQKPQNKTNIEKSKQIKPKQYNQTKNHQQQKKN"
     gene            5278..6144
                     /locus_tag="RFE25_002500"
     CDS             5278..6144
                     /locus_tag="RFE25_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDU2817533.1"
                     /translation="MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFG
                     VDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIG
                     QTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFND
                     DHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKE
                     MLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFV
                     NLMASFVEQPKA"
     gene            6276..7496
                     /locus_tag="RFE25_002501"
     CDS             6276..7496
                     /locus_tag="RFE25_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter"
                     /protein_id="HDU2817534.1"
                     /translation="MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGM
                     TTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTI
                     WLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPF
                     IGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKD
                     KTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILG
                     VLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQ
                     DILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFF
                     TKNQKITKEDMIST"
     gene            7493..7981
                     /locus_tag="RFE25_002502"
     CDS             7493..7981
                     /locus_tag="RFE25_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF456 domain-containing protein"
                     /protein_id="HDU2817535.1"
                     /translation="MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHN
                     QHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFG
                     IIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALL
                     IN"
     gene            complement(8080..>8733)
                     /locus_tag="RFE25_002503"
     CDS             complement(8080..>8733)
                     /locus_tag="RFE25_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HDU2817536.1"
                     /translation="VKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLL
                     SAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFL
                     GFFMEKNGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAII
                     LLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL"
BASE COUNT         3194 a         1090 c         1490 g         2959 t
ORIGIN      
        1 ttaaccatta tatagtttta tttatttttg atttggtatt cgtattgtgt taaatttacg
       61 tttaattaaa taagttaaat attataggga atgataaaag tggtacttaa atatagaaag
      121 aggtaaagtt atggcaaaat catgcttgca tatacttact aataatgaat atgcgacaac
      181 gcgttgccaa gatggcatag tcttattttg gccaattgac ggggaaatcg aactacaaaa
      241 atttcgtaaa agtaaaataa ttgaagatga tatatatatt attaatcatc tggatgtatt
      301 tagtattaag aataataaaa aaacgatcat gttgtatttg agtagcgatt ggtttgcgga
      361 attaggcttt actttcttta attaccacta tacagcaaag ttgattaaat catcctataa
      421 tttgaaatgt ctactattaa aattgactta tcgatatctt gataatcaac ctctcaatga
      481 cgctgatatt agaaaattac aggatattat taaaatcatt gcaaaagaag caagtatgga
      541 taaaaagatt gcgcaaaatc aatatcgata tgcctattat ggtgatttac gtgacgagct
      601 cgaatatatt tatcaaaatg taaatcaacg attgacatta aaaagtgtcg ctgataaatt
      661 atttgtctca aagtcaaatt tgtcatcaca attccactta cttatgggca tgggttttaa
      721 aaaatatatt gatactttga aaattggtaa atcgattgaa attctactta ctactgatag
      781 tactattagc aacataagtg agcatttagg ttttagtagt agctccactt actctaaaat
      841 gtttaaaagt tatatggata taacaccgaa tgaatatcgt aatttatcaa aatataataa
      901 atgtttaatg ctaaagccag aaccactagt aggcaaaatg gtgcaagaag taaaagaaat
      961 catattgaat tatattgaac attataaaaa ccacctaact gatgttatac atattgatga
     1021 agacaaattt gaaacaccta aattgtttca aacggttatt caaataaata cttatacaga
     1081 aatgaaatta gttttcttag aaggaatctt taaaacctta ttgaataaga acagtcaagt
     1141 tgtctttttc atcatgccat cgattctaaa aagtaaaaat accatgtccg aagaagaaaa
     1201 attcacaatc attaaaacaa taattgaaag tgatctaaag atagcattta atataaatga
     1261 tattgaaaca acttattttg ttgaagaagc ttttatgagt gttttcagac aaatatctcc
     1321 aaacgaatta agtaatcata ataattacga agtgcatttt gtttttgatt tatcattgat
     1381 ggaaattaga acaatttatc gaatgatatt aaaattacat aacatcatgt tgaatgtgaa
     1441 attaggattg aacattacct gtttatttga aaaaccttca gtttttaaat cactagtatc
     1501 acaaataaag cgacttaaat tcgattcgtt aataatagat aatgcaaatt taagtagccc
     1561 ttatttgatg ggggaaagtg atgagttact attgaaaaat attttgcatt ttaaaaattt
     1621 aaaacaagta attaatgaat tggatattga acaagaaaag cttatttttc taaatgttga
     1681 aaatcataaa ctgcttaata ataaagaacg agatttaagt aatagtgctc cattaattta
     1741 taagacatta agtgcgctgt atcacaactt tgatggcttt ggattaaaca tttttgataa
     1801 tcatcataca tttaatgcga tgcatctata tgataaaaat ggatttaaaa caacactagg
     1861 tcttatattg gaaaaattta tcgaatatgt ctcgaaacca aaatacgaaa acagttatta
     1921 ttctattttt gatatagaga attattattg cctggttatt tatgattggc gagtgattga
     1981 gagcgagaca attatgagca attttgagga tagtcaagtt tatataaatt tcaaaaataa
     2041 tgttttaaac gataaatatc taattgtaat agaaacattg gacgaaaata gtggcaacat
     2101 taatcatttg atttctaaag aattaagaga taaatatgaa tggaacccta gtttactatc
     2161 taaaattgac aactacctta aaccagcaat cgagattaaa gagcataatt ttagtgataa
     2221 ttccttgaat attaacgtta cttttaatgc gttatacata attaaaatag gaaaaaaata
     2281 acaccttgat atgtattaca aaatttaatt tgcatttgtt ggtaattttg acaacgtatt
     2341 aaaaacaaat gagaaagaca atggcaaaaa aatttaagat aataatgaca gaagcattgt
     2401 ctttatatat ttgggggtgc aacattttga atactgagaa attagaaaca ttgcttggct
     2461 tctataaaca atataaagca ttatctgaat atattgataa aaaatataag ttgtcgctaa
     2521 atgatttagc agtcttagat ttaacgatga agcattgcaa agatgaaaaa gtacttatgc
     2581 aatcattttt aaaaactgca atggatgagc tagatttaag taggacaaaa ttattagttt
     2641 ctataagaag actaattgaa aaagaaagac ttagtaaagt tagatcatct aaagatgagc
     2701 gtaaaattta tatttattta aataatgatg atatatctaa atttaatgct ttatttgaag
     2761 atgtagaaca atttttaaat atttaattga aattgagtgt cgaaagcata gaatttgctt
     2821 atcggcacat ttttaattta tacatatttt aaaactaagt aacagtttga aggaatcgta
     2881 gttcaataat gttaattgtg aaaatgtata taaacataaa aaaatcatgt ataatatatg
     2941 ttgttaatta aacagttcga aagcgagatg acattatggg acgtaaatgg aataacatta
     3001 aagaaaaaaa ggcccaaaaa gataaaaaca caagtagaat atatgcgaaa tttggtaagg
     3061 agatttatgt tgcagcaaaa tctggtgaac ccaatccaga atctaaccaa gctttaaggt
     3121 tggtgcttga acgcgctaag acatattcag tgccgaatca tattattgaa aaagcaatag
     3181 ataaagctaa gggtgctgga gacgaaaact ttgatcacct aagatatgaa ggatttggcc
     3241 caagcggatc aatgctaatt gttgatgcgt taacaaataa tgtaaatcgt actgcctctg
     3301 atgtgcgagc tgcttttggt aaaaacggcg gtaatatggg tgtatctgga tcagttgctt
     3361 atatgtttga tcatgtggca acatttggta ttgaaggaaa gtctgttgac gaaatacttg
     3421 aaacattaat ggaacaagat gtagatgtaa atgatgtgat tgacgataat ggattgacaa
     3481 tagtctatgc tgaaccagat caatttgcag tcgttcaaga tgcgcttcgt gcagcaggtg
     3541 ttgaagaatt taaagttgct gaatttgaaa tgttacctca aacagatatt gaactttctg
     3601 aagcggacca agtaacattt gaaaaattaa tcgatgcatt agaagattta gaagatgtac
     3661 aaaacgtatt ccataatgtg gatttgaaat aatgaaatca gcagaacaat ggattgatga
     3721 attgcaactt gaatcacatc ctgaaggtgg tttctataga gagacaattc gagaagtatt
     3781 gaaagatgga cgcagagcgc cgtttagtag tatttatttt ttacttacag atgacaatat
     3841 ttcgcatttt catcgaattg atgctgatga agtatggtac tatcatgctg gtgattctct
     3901 aacaattcat atgataaatc cggatgggga atatacgact gcaacattgg gtactgatat
     3961 ccaaaatgga gatgtattgc aatatgtagt gcctaaagga acaatttttg cttcttcaat
     4021 cgaaatttca aatacttata gtttagtagg ttgtatgtgt caaccggcat ttgagtttaa
     4081 gcagtttgaa ttgtttaagc aatctgaatt aattacacaa tatccgcatc ttaaatcagt
     4141 gattgaaaaa tatgctttaa aataaaaatg atcaatgaag tggtttgaag gttgttaata
     4201 aacctttgag tcacttcatt tttatatgta ttcttgattg aatcagaata gatttgatgc
     4261 ttcagctgtt tttaatgaaa atagcattaa atgattttga aaacgataag agtgtgttat
     4321 ttatattttt gaaaaatcac ttttatgaag aaatgtgtgt actatctaat taatattgtc
     4381 tattttaagt aaattgaagc gagttgtagt aaaataataa taaatatttt catatgatta
     4441 acaaaaacta taaaactgta tcatgacatg acatcattta tgtagtttta tataataatg
     4501 acaaggagtt ggtgactgtg aaagtaaagt atatagataa acgtcactgg cgtcgcctaa
     4561 ttgataggga atacacagag gtaaaagtta ataataatag gtttaagggt attataggct
     4621 tagtcacgat gaaaaaggtt cgtgatcctt tagaggtgac ggtagttgga caaaatatca
     4681 ttgtcgcaga tgacaattat aaatggttgc aaatactacc tgaaaagaaa cgttatagta
     4741 taactgtaat gtttgataat aaaggcaatc cattagaata ttattttgat ataaatatca
     4801 aaaatataac gcaaaaaggt aatgcgcgta cagtagattt atgtttagat gttttagcat
     4861 taccaagtgg tgaatatgag ttggtagatg aagatgattt aatgtttgca ttagaaagtg
     4921 agcaaattac aaaaaagcaa tttcatgaag catatatgat tgcacatcaa attatggcag
     4981 agttagaaaa tgattttaaa ggattccaaa agaaaatcat gtactgcttt aataaaatta
     5041 atgcaaaggc tcaaaaaaat catcaaaagc cacaaaataa aactaatatt gaaaaaagca
     5101 aacaaataaa acctaagcaa tataatcaaa ctaaaaatca ccaacaacaa aagaaaaact
     5161 aagtaattca agctgcagcc atgccaataa aattggtgaa attattcgtt agtaatgaac
     5221 tcatgaatgc ttgtagccat gaaagttcaa taattgaata atttatgggg ggaaattatg
     5281 aagattgaag actatcgttt actaataaca ttagacgaaa cgaaaacgtt acgtaaagcg
     5341 gctgaaattt tatatatatc tcaacctgct gttacacaaa gactaaaagc tattgaaaat
     5401 gcttttggag tagatatttt tatcagaaca aaaaaacaat tgattacaac aactgaagga
     5461 acaatgatta ttgagcatgc ccgtgacatg ttgaaaagag agcgattatt ttttgacaaa
     5521 atgcaggcac atattggtga agtgaatgga acaatatcaa tcgggtgttc ttctttgatt
     5581 ggacaaacct tacttcctga agttttgagc ctatataatg cccaatttcc taatgttgaa
     5641 atacaagtgc aagttggttc aactgaacaa attaaagcaa atcatagaga ttatcatgtt
     5701 atgataactc gtggaaataa ggtaatgaat ttagctaaca cacatttatt taatgatgat
     5761 cattatttta tttttccaaa aaatagacga gatgatgtta caaagttacc atttatagag
     5821 tttcaagctg atccgattta tataaatcaa ataaaacaat ggtataacga taatttagaa
     5881 caagattacc atgcaactat tacagtggat caagtagcaa cttgcaaaga aatgttgatt
     5941 agtggtgtag gtgttacaat tttgccggaa attatgatga aaaatatcag caaagaacaa
     6001 tttgagtttg aaaaagtaga aattgataat gaaccgctga ttcgttcgac atttatgagt
     6061 tatgatccga gcatgttgca attgccacaa gttgattctt ttgtaaatct catggcgagc
     6121 tttgttgaac aaccaaaggc gtagttttag actaatttaa ggtttgtatt taattttaaa
     6181 ctattcggtt aaattgaacg tagttgtttg ctaacgcacc aacagcaaaa gagcccctaa
     6241 ttaataaatt aaaaggggct ctaagaagcg gggttatgga tatgtttgca gcgttattac
     6301 aaataaagaa ttataaactc tttgttgcta atatgtttct actaggtatg ggtattgcgg
     6361 ttacggtccc atatcttgtt ctttttgcaa ctaaagattt aggtatgaca acaaatcagt
     6421 atggattact tctagcatct gcagcgatta gccagtttac agtaaattca attattgcta
     6481 gattttcgga tacgcatcac tttaatagaa aaattattat tattctcgca ttattaatgg
     6541 gtgcgcttgg tttttcaata tacttttttg tagatacaat ctggttattc atattactat
     6601 atgcgatttt ccaaggatta tttgcaccag caatgcccca actttacgca tctgctagag
     6661 aatctatcaa tgtttcaagc tctaaagata gagctcaatt tgccaacaca gtattacgtt
     6721 caatgttctc attgggcttt ttatttggtc catttattgg tgcccaatta atcggtttaa
     6781 aaggctatgc tggattgttt ggtggaacaa taagtatcat tttatttact ttagtacttc
     6841 aagtgttttt ctataaggat ttaaacatta aacaccctat tagtacgcaa caacatgttg
     6901 aaaaaattgc tcctaatatg tttaaagaca aaacgctttt attaccattt attgcattta
     6961 ttttattaca cattggacaa tggatgtata cgatgaatat gcctttattt gttactgatt
     7021 atttaaaaga aaatgagcaa catgtcggtt atttagctag tttatgtgct ggtttagaag
     7081 tgccatttat gatcattctt ggcgttttat catctagatt acatactcga acattgttga
     7141 tttatggagc gatttttggt ggtttattct acttcagcat tggggtattt aaaaacttct
     7201 atatgatgtt agcaggacag gtatttttag ctattttctt agcggttctt ttaggaattg
     7261 gtattagtta tttccaagat atcttaccag attttccagg atacgcctca acactatttt
     7321 ctaatgcaat ggttattgga cagttaggcg gtaacctatt aggtggtgct atgagtcact
     7381 gggtaggttt ggaaaatgta ttttttgtat cagcagcatc aatcatgtta ggtatgatac
     7441 ttatattctt tactaaaaat caaaaaatta caaaagagga tatgatatca acatgacaat
     7501 tattttatgg ctacttatca tcgctgcctt catgttagca tttgttgggt tgattaagcc
     7561 gattattcct tctgttttag tattatgggt tggctttcta atctatcaat ttggctttca
     7621 taatcagcat ttatcatggg tgttttatgt atctatggca ttgctaacaa tactaatttt
     7681 atgtgcggac tttttagcta ataaatattt tgtgaatcgc ttcggtggtt ctaagtttgg
     7741 agagtatgca gctttaattg gtgtggttat tggatgtttt gttttaccgc catttggaat
     7801 tattattata ccttttattt tggtattcat agttgaatta atacaaggct attcatttga
     7861 aagagcagtt aaagtaagta taggttcaat cgtagcattt ttaacaagta gtatagctca
     7921 agcaatcatt atgtttataa tgattgtatg gttctttata gatgctttat tgattaatta
     7981 ataaaaagct tattgcaaaa tatgtttttc ggtaactgta atttagtgat tttatcatta
     8041 acagtaccaa attcgcatat gatgtaataa gctttttgtt tataaaaatg tatgagaatg
     8101 ttttttcgaa atatttcttt caatgcgtaa tccaataggc ataactataa atgaaaatat
     8161 aataaatacc caattgctta cctgaatata tggtccaaag gcaagtaatg attgtggaat
     8221 aaagaataca tagaaaaatc ctacaattag tagaatgatt gctaaatagg tgaatatcca
     8281 tatccaattt gaattgttaa aacactgcag ttgtattgtt ttaaaactaa accatataaa
     8341 taaaaagaca ataaagaatc caacgactac tgaaaacggg aatgaaacaa aatataaatt
     8401 acttccattt ttttccatga aaaatcctaa aaatcctttg agaaaactaa caatcccaat
     8461 taatagaacg atgtgttgat agatatattt aaaaatattt ttaaatgttt cattaggcat
     8521 cgcttttagt tcttttattg catgtgcttt tgggtcgtga ttgaaaaaat ctaaggctaa
     8581 taaaccatgt tgttctgcgc ttaataattg tttgagtata cggttaataa ttaactctgt
     8641 atcatgaggg ttgacgcgaa agtcagagcg catataagtc atataattct cgaagatttc
     8701 tctatcagta ttgcttaatc ttaatgattt aac
//
LOCUS       DAPDIM010000089         8715 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000089 DAPDIM010000000
VERSION     DAPDIM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8715
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.089"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            147..1202
                     /locus_tag="RFE25_002504"
     CDS             147..1202
                     /locus_tag="RFE25_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDU2817537.1"
                     /translation="MTGFSVYLGQPLDEAYIKRMIKQGYQMIFTSVQIPEEDDETKYH
                     YFTKLLNLLKYEQVTYLIDANPSILTPSFYEHLRQYDAQFMIRIDHSTSIEAIEAIMA
                     QGLKCCLNASIISRELLTSLHQQLNDFTLLSFCHNYYPRPDTGLSVDLVNKKNELIYQ
                     FNPKAQIYGFIVGSGLRGPLHKGLPTIEATRHSHPVVAAKLLQETGVSEVLVGDSLIE
                     MRQAKQLIDFCKHRHFTLCIEEVFDTTVTYLFDMCHKVRPDNPENVIRSETSRQICPH
                     SIQPQFTTQRRIGSVTVDNLNNGRYQGEMQIVRQTLSAHDNVNVVAQIIKEDLPLLSC
                     IEPNDTFDFQKTRECKK"
     gene            1202..2098
                     /gene="murQ"
                     /locus_tag="RFE25_002505"
     CDS             1202..2098
                     /gene="murQ"
                     /locus_tag="RFE25_002505"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDU2817538.1"
                     /translation="MENSTTEARNEATMHLDEMTVEEALITMNKEDQQVPLAVRKAIP
                     QLTKVIKKTIAQYKKGGRLIYIGAGTSGRLGVLDAAECVPTFNTDPHEIIGIIAGGQH
                     AMTMAVEGAEDHKKLAEEDLKNIDLTSKDVVIGIAASGKTPYVIGGLTFANTIGATTV
                     SISCNEHAVISEIAQYPVEVKVGPEVLTGSTRLKSGTAQKLILNMISTITMVGVGKVY
                     DNLMIDVKATNQKLIDRSVRIIQEICAITYDEAMALYQVSEHDVKVATVMGMCGISKE
                     EATRRLLNNGDIVKRAIRDRQP"
     gene            2110..3564
                     /locus_tag="RFE25_002506"
     CDS             2110..3564
                     /locus_tag="RFE25_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDU2817539.1"
                     /translation="MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQ
                     ELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYK
                     SYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLM
                     VAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTG
                     IAGKNILMNVFTGEPLQPGQGGIIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIAL
                     LIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFT
                     PIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGI
                     GEPLIYGVTLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYL
                     GYIAGLLAAYAGGFVCTYLFGTTKAMRQTDLLGD"
     gene            3567..4442
                     /locus_tag="RFE25_002507"
     CDS             3567..4442
                     /locus_tag="RFE25_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDU2817540.1"
                     /translation="MTNILYRIDKQLSDFTKTEKIIADYILKNPHKIIDMTVNDLADV
                     TNVSTASIVRFSRKMTHQGFQELKIAISRYLPEDIATNPHLELIENESVETLKNKMIA
                     RATNTMRFVATNIMDAQIDAICDVLKNARTIFLFGFGASSLTIGDLFQKLSRIGLNVR
                     LLHETHLLVSTFATHDDRDCMIFVTNQGSHSELQSIAQVATHYSIPIITISSTANNPV
                     AQIADYALIYGRTDENEMRMAATTSLFAQLFTVDILYYRFVALNYHAILDCITQSKMA
                     LDNYRKHLATIDFKH"
     gene            complement(4636..4917)
                     /locus_tag="RFE25_002508"
     CDS             complement(4636..4917)
                     /locus_tag="RFE25_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817541.1"
                     /translation="MVLITYQIILFFIISLSYYLTLNHYMAVTVGNFTSIFGMFAAIL
                     FMYYYLLYKSPEYNQRKRFKHFIHITNLIIIAFSTFVLVHLALKLFFSI"
     gene            5130..7919
                     /locus_tag="RFE25_002509"
     CDS             5130..7919
                     /locus_tag="RFE25_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDU2817542.1"
                     /translation="MAYQSEYALENEMMNQLEQLGYERVTIRDNKQLLDNFRTILNER
                     HADKLEGNPLTDKEFQRLLTMIDGKSIFESARILRDKLPLRRDDESEIYLSFLDKKSW
                     CKNKFQVTNQVSVEDTYKARYDVTILINGLPLVQVELKRRGIDINEAFNQVKRYRKQN
                     YTGLFRYIQMFIISNGVETRYFSNNDSELLKSHMFYWSDKQNNRINTLQSFAESFMRP
                     CQLAKMISRYMIINETDRILMAMRPYQVYAVEALIQQATETGNNGYVWHTTGSGKTLT
                     SFKASQILSQQDDIKKVIFLVDRKDLDSQTEEEFNKFAKGAVDKTFNTSQLVRQLNDK
                     SLPLIVTTIQKMAKAIQGNAHLLEQYKTNKVVFIIDECHRSQFGDMHRLVKQHFKNAQ
                     YFGFTGTPRFPENSSQDGRTTADIFGRCLHTYLIRDAIHDGNVLGFSVDYINTFKNKA
                     LKAEDNSMVEAIDTEEVWLADKRVELVTRHIINNHDKYTRNRQYSSIFTVQSIHALIK
                     YYETFKRLNKKLEQPLTIAGIFTFKPNEDDRDGEVPYHSREKLEIMISDYNKKFETNF
                     STDTTNEYFNHISKNVKKGVKDSKIDILIVVNMFLTGFDSKVLNTLYVDKNLMYHDLI
                     QAYSRTNRVEKESKPFGKIVNYRDLKKETDDALRVFSQTNDTDTILMRSYEEYKKEFM
                     DAYRELKMIVPTPHMVDDIQDEEELKRFVEAYRLLAKIILRLKAFDEFEFTIDEIGMD
                     EQENEDYKSKYLAVYDQVKRATAEKNKVSILNDIDFEIEMMRNDTINVNYIMNILRQI
                     DLEDKAEQRRNQEQIRRILDHADDPTLRLKRDLIREFIDNVVPSLNKDDDIDQEYVNF
                     ESIKKEAEFKGFAGERSIDEQALKTISNDYQYSGVVNPHHLKKMIGDLPLKEKRKARK
                     AIESFVAETTEKYGV"
     gene            complement(8066..8665)
                     /locus_tag="RFE25_002510"
     CDS             complement(8066..8665)
                     /locus_tag="RFE25_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020808034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817543.1"
                     /translation="MSLSKLPLFNHFANIRIQPKLIIKLFLTLIIIVTYTFVSGLSVD
                     YKKLLSEAGLSETSLAQIKIFSQISIFFSRVFSVLFTFLIILVISRIMRSDANTKSIF
                     SATLSYILFTNAISLIILTIQISAGLSLIDYSITSLNIFAKGNRILGTFDLQFFVQAY
                     ILTVMLIGTSKLSIRASTIWGIIYLILIITFSLISISIQ"
BASE COUNT         3095 a         1230 c         1727 g         2663 t
ORIGIN      
        1 acttgtgaca gaaatatgta agattattac aatgaacagg ctttaactga ttaatattgt
       61 aatgtgtttt ctcttatagt aaaatgtaag cgattacaca actcaactat attttcctaa
      121 taattatatt gataaggagg gctactttga caggcttttc agtgtattta ggacaacctt
      181 tagatgaagc gtatattaag cgaatgatta aacaaggtta ccaaatgatt tttacatctg
      241 tacaaatacc agaagaagat gacgagacaa aatatcatta tttcacaaaa ctactcaatt
      301 tattaaaata tgaacaagtg acttacctca tagatgctaa tccatctatt ttaacaccat
      361 ctttttatga gcatcttcga caatatgatg cacaatttat gattcgtatc gatcatagta
      421 catcaattga ggcaatcgaa gcgataatgg cacagggttt aaagtgctgt ttgaatgcaa
      481 gtattatttc ccgggaattg ttaacaagct tacatcaaca attgaatgat tttacattac
      541 tttcattttg tcataactat tatccaagac cagatacggg attatctgtt gacttggtca
      601 ataagaaaaa tgaactcatt tatcaattta atccaaaggc acaaatatat ggttttattg
      661 tagggagtgg tttgcgaggt cctttgcata aaggcttgcc aacaattgaa gcaacgagac
      721 atagtcatcc tgtcgttgca gctaaattat tacaagaaac tggtgtatct gaagtgttag
      781 ttggagactc attgattgaa atgaggcagg caaaacaact tatagatttt tgcaagcata
      841 ggcatttcac gttatgtatt gaagaagtgt ttgatacgac agtgacttac cttttcgata
      901 tgtgtcataa agtacgcccg gataatccgg aaaatgtcat tcgttcggaa acgtcaagac
      961 aaatatgtcc acattcgatt caaccacagt ttacgacgca acgacgcatt ggttcagtaa
     1021 ccgttgataa tttgaataac ggacgttatc aaggcgaaat gcaaattgtg agacaaacgc
     1081 ttagtgcaca tgacaatgtg aatgttgttg cacaaattat taaagaagac ttaccactgt
     1141 taagttgtat cgagccgaat gatacatttg attttcaaaa aactagggag tgtaagaagt
     1201 gatggaaaat agtacgaccg aagcgcgtaa tgaagcgacg atgcatcttg atgaaatgac
     1261 tgtggaagag gctttaatta cgatgaataa agaagatcag caagtcccgt tagcagttcg
     1321 aaaggcaata ccacaattga caaaagtaat aaaaaaaaca attgcacagt ataaaaaggg
     1381 tggacgattg atctatatcg gtgcaggtac aagtggaaga ttgggtgtct tagatgcagc
     1441 ggagtgtgta cctacattca atactgaccc tcatgaaatt ataggtatta ttgctggtgg
     1501 acaacatgct atgacgatgg ctgtagaagg tgcggaagat cacaaaaaat tagcggaaga
     1561 agatttgaaa aatatagatt taacatcaaa agatgtcgtt ataggaattg ccgcgagtgg
     1621 caaaacgcca tatgttatag gcggtttaac atttgctaac acaatcggtg ctacaacagt
     1681 atctatttca tgcaatgaac atgcagttat aagtgaaatt gcgcagtatc cagtagaagt
     1741 taaagttggt ccagaagtat taactggttc aacacgttta aagtctggta cagcacaaaa
     1801 gttaatttta aatatgattt caaccatcac aatggttggt gtcggaaaag tttacgataa
     1861 cctcatgatt gatgttaaag caaccaatca aaaactgatc gaccgttcag tgcgtattat
     1921 tcaagaaata tgtgctatca catatgatga agcaatggcg ttatatcagg tatctgagca
     1981 tgatgtgaaa gttgcgacag ttatgggtat gtgtggcatt tctaaggaag aagcaacaag
     2041 acggttatta aacaatggtg acattgttaa acgagcaatc agagatagac aaccttagga
     2101 gggatttaaa tgaccaaaga acaacaactt gcagaacgaa ttattgctgc agtaggtggt
     2161 atggataata tagatagtgt catgaactgc atgacacgtg tgcgtattaa agtattagat
     2221 gaaaataaag tagatgacca agaactaagg catattgatg gtgtcatggg tgttatacac
     2281 gatgaacgca ttcaagttgt ggttggacct ggtacagtca ataaagtggc taatcatatg
     2341 gcggaattaa gtggtgttaa actaggtgac ccaataccac accatcacaa tgatagtgaa
     2401 aaaatggact ataaatcata tgcagctgat aaagcaaagg cgaataaaga agcacataaa
     2461 gcaaaacaaa agaatggtaa gttgaataaa gtattgaaat caattgccaa tatctttata
     2521 ccgttgattc ctgcatttat tggagctgga ttaattggtg gtattgcagc agtactgagt
     2581 aacttaatgg tggcaggcta tatttcaggt gcttggatta cgcaacttat aacagtattc
     2641 aatgtcatta aagacggtat gttagcatac ttagctattt ttactggtat taatgcggct
     2701 aaagaatttg gtgcaacacc aggacttggt ggcgtgattg gtggtacaac gttattaacg
     2761 ggtattgctg gtaaaaatat tttaatgaat gtcttcactg gagaaccatt gcaacctgga
     2821 caaggtggaa ttattggcgt tatttttgcc gtttggattt taagtattgt cgaaaagaga
     2881 ttgcataaaa ttgtgccaaa tgcgattgat attattgtaa cgccgactat tgcattgttg
     2941 attgtaggac tattaactat ctttatcttt atgccattag caggttttgt ttcagacagt
     3001 ttagtttcag tagttaacgg aattattagt attggtggcg tatttagtgg atttatcatt
     3061 ggagcaagct tcctaccgtt agttatgtta gggcttcatc atatttttac gccaattcat
     3121 atagaaatga ttaaccaatc tggtgctact tacttattgc caattgcagc gatggctggt
     3181 gctggacaag taggtgccgc attagcactt tgggtaagat gtaaacgcaa cacaacatta
     3241 cgtaatactt taaaaggtgc attgccagtt ggtttcctag gtatcggaga accattaatc
     3301 tatggtgtga ctttgccatt aggtcgacct ttcttaactg cttgtattgg tggtggtatt
     3361 ggtggcgctg taataggtgg aattggacat attggtgcca aagcaatagg cccaagtggt
     3421 gtgtcactct taccattaat ctcagataat atgtatttag gttatattgc aggattactt
     3481 gctgcatatg ctggtggatt cgtttgtaca tatttatttg gaacgacaaa ggcgatgcga
     3541 cagacagatt tgttgggtga ttaatgatga caaatatttt atatcgcatt gataaacagt
     3601 tgagtgattt tacgaagaca gaaaagataa tcgctgatta cattttaaag aatccacata
     3661 aaatcattga tatgacggtg aatgatttgg cagatgttac gaatgttagt acagcatcaa
     3721 ttgttagatt tagtcggaaa atgacacatc aaggttttca agagctaaag attgcgatat
     3781 ctcgatactt acccgaagat attgcaacca atccacattt agaattgatt gaaaatgaat
     3841 ctgtagaaac tttgaaaaat aaaatgattg ctagagcaac gaatacgatg cgatttgtag
     3901 ctactaatat tatggatgcg caaattgatg caatttgtga tgtgttgaaa aatgccagga
     3961 caatattttt atttggattt ggcgcatcga gtttgactat tggtgatctt tttcaaaagt
     4021 tatctcgtat tggcttaaat gtcaggttat tacatgaaac gcatttactt gtgtcaacat
     4081 ttgcgacgca tgatgataga gattgcatga tttttgtgac gaatcaaggt agtcatagtg
     4141 aattgcagtc aattgcacag gtggccacac attacagtat tcccatcata actatatcta
     4201 gtacagctaa taatccagtg gctcaaattg cagactatgc attgatttat ggcagaactg
     4261 atgaaaatga aatgcgtatg gcggctacaa cttcactatt tgcacagtta ttcacggtag
     4321 atatattgta ctatcgattt gtagcattaa attatcatgc gattctagat tgtataaccc
     4381 aatcgaaaat ggcacttgat aattaccgga agcatcttgc gacgatagat tttaaacatt
     4441 agatattgtg agcgttctaa tataaagtta gttgcaacgt aaacaattga agtttttgat
     4501 gtgattcagt tgtttgatga aaaattgttg ctacaagttt gtaaaactgg catagaggct
     4561 attttgaaaa tgataaaggc gtgacaaatt aaagcaaagt tcaggtttga gctttgcttt
     4621 tttcatagat ggaaattaaa tgctgaagaa taattttaat gctaaatgaa ctaatacgaa
     4681 ggtgctaaaa gcaattatta tcaaattagt gatatgaatg aaatgtttaa atcgtttgcg
     4741 ttgattgtat tcgggacttt tatagagtag gtagtagtac ataaagagta tggctgcgaa
     4801 catgccgaat attgaagtga agttacctac agtgactgcc atgtaatgat ttaaagttaa
     4861 atagtaactt agactaataa taaaaaataa aatgatttga taggtaatta acaccattca
     4921 agtccctcca ttaatcgtag acaaaaaatt tatcaatgat ttgattattt gtattcaaat
     4981 tttagtatac gacttacctc aaagacaaat attaaaagat aagacaataa aattagaata
     5041 aatttacgtt tgaagataaa aaacaaacat ttttcattaa agtttatgat atatttagag
     5101 caatagaaag tgtatggaag gggatatgaa tggcatacca aagtgaatac gcattagaaa
     5161 atgaaatgat gaatcaactt gaacaattgg gttacgaaag agtaacgata cgtgataata
     5221 agcaattgct tgataatttt agaacgattt taaatgagcg tcatgcggac aaattagaag
     5281 gcaatccctt aacagataaa gaatttcaac gtctgttaac gatgattgat gggaaaagta
     5341 ttttcgagag tgcccgtatt ttacgtgata aattaccact tagacgtgat gatgagtctg
     5401 agatttattt gtcgttttta gataagaaaa gttggtgtaa aaataagttt caagtgacga
     5461 atcaagtatc tgtcgaggat acatataaag cacgttatga tgtaacgata ttaatcaacg
     5521 gactacccct tgtccaagtt gaattgaaac gtcgaggtat tgatattaat gaggcgttta
     5581 accaagtaaa acgttaccgc aaacaaaatt acacaggctt attccgctac atacaaatgt
     5641 ttatcattag taatggtgtt gaaacgcgat acttttctaa taatgatagc gaactattga
     5701 agagtcacat gttttattgg agtgataaac agaataaccg aatcaataca ttacaatcat
     5761 ttgctgagtc gtttatgaga ccctgtcaat tagctaagat gatatcgcgc tatatgatta
     5821 ttaatgaaac agatagaata ctgatggcaa tgcgtccgta tcaagtgtat gcggtagaag
     5881 cacttattca acaagcgact gagacaggga ataatggata tgtatggcat acaactggaa
     5941 gtggtaagac attgacttct tttaaagcga gtcagatttt atcacagcaa gatgacatta
     6001 agaaagttat ctttttggtt gaccgtaaag acttggatag tcaaacagaa gaggaattta
     6061 ataaatttgc taagggtgct gtagacaaaa cttttaatac ctcgcaactg gtacgccaac
     6121 taaatgataa aagtttgcca cttattgtaa cgacgattca aaaaatggct aaagcgattc
     6181 aagggaatgc ccatttatta gaacagtata aaacgaataa agttgtattt attattgatg
     6241 agtgtcatcg cagtcaattt ggtgacatgc atcgtctagt taaacaacat ttcaaaaatg
     6301 cccaatactt tggattcact ggtacgccac gttttccaga aaatagtagt caagatggta
     6361 gaacaactgc agatattttc ggtagatgct tacatacgta tttaattaga gatgccattc
     6421 atgatggtaa tgtacttggt ttctcagttg actatattaa tacttttaaa aataaagctt
     6481 taaaagcaga agataacagc atggttgaag caattgatac ggaagaagta tggttagcgg
     6541 ataaacgtgt ggaattagta acacgacata tcatcaataa tcatgataaa tatacacgta
     6601 atcgtcaata ttcaagtata tttacagtcc aaagtattca cgcgcttatt aaatattatg
     6661 agacatttaa gcgacttaac aaaaagttgg aacaaccgtt aacgatagct ggtatattta
     6721 cgtttaaacc taatgaagat gatcgtgatg gtgaagtgcc atatcattca cgtgaaaaat
     6781 tagagataat gattagtgat tataataaaa agttcgagac gaatttttca acagacacaa
     6841 ctaatgagta ttttaatcat atttcaaaaa acgttaaaaa gggcgttaaa gatagtaaaa
     6901 ttgatatctt aatcgttgtt aatatgttct taactggttt tgatagtaaa gtactgaaca
     6961 ctttatatgt tgataagaat ttaatgtatc atgatttaat tcaagcgtat tcacgtacaa
     7021 atagggttga aaaagaatca aagccatttg gtaaaattgt aaactatcgt gacttgaaaa
     7081 aagagacaga cgatgcactg agagtattct cacaaacaaa tgatacggat acaattttaa
     7141 tgcgcagtta tgaagagtat aaaaaagaat ttatggacgc ttatcgtgag cttaaaatga
     7201 ttgtgccgac accacacatg gttgatgaca ttcaagatga agaagagcta aagcgctttg
     7261 ttgaagctta tcgtttatta gctaaaataa tattacgttt aaaagcattt gacgagtttg
     7321 agtttacaat tgatgaaatt ggaatggatg aacaagagaa tgaagactat aaaagtaaat
     7381 atttagctgt gtacgatcaa gtaaaaagag cgacggctga gaaaaataaa gtatccattt
     7441 taaatgatat tgatttcgaa atagaaatga tgcgtaatga tacgattaat gtgaattata
     7501 ttatgaatat attgagacaa attgatcttg aagacaaagc ggaacaacgt cgtaaccaag
     7561 aacaaattag acgcatttta gatcatgcag atgatccgac attgaggtta aaacgagatc
     7621 taattagaga attcatcgac aatgttgtac cttctttaaa taaggatgat gatatcgatc
     7681 aagaatatgt taatttcgaa agtattaaaa aagaagcgga gttcaaagga tttgctggag
     7741 agagatctat cgatgaacaa gccctaaaaa caatttcaaa tgactaccag tatagtggtg
     7801 ttgtaaaccc acatcacctt aaaaaaatga ttggtgattt gccattgaaa gaaaagcgta
     7861 aagcaagaaa agccattgaa tctttcgtgg cagaaacaac tgaaaaatac ggtgtgtaat
     7921 gattcagccc cctcgctaga ttagtgtagg gggcattatt atttcattag aaaaggctca
     7981 tttgttaaat tcatcttatc aagaatataa cgaatgttcc ttgttttaaa cttattaatt
     8041 aatagagaca ttttatctga aaatatcact gaatgctaat actaatcaaa gaaaaagtga
     8101 taattaaaat aagatatata ataccccaaa tagtggatgc tcgtatagaa agtttcgacg
     8161 taccaattag catgactgta agtatgtatg cttgtacaaa aaattgtaag tcgaaagtac
     8221 ccagaatgcg atttccttta gcaaaaatat ttaaactagt aatagaatag tcaattaatg
     8281 ataaaccggc acttatttgg atggtaagta taattaaact aatagcattt gtaaacagta
     8341 tgtagcttaa cgttgcagag aatatagatt ttgtattagc atctgagcgc ataattctag
     8401 agataactag aatgattaaa aatgtaaata atacgctgaa aactcttgag aaaaaaatac
     8461 taatttgact aaaaattttt atttgtgcta atgatgtctc tgagagtcct gcttcactca
     8521 ataacttttt atagtccaca gatagtccac taacaaatgt atatgtaaca attattatca
     8581 aagtcagaaa cagcttaatg attaactttg gttgaatgcg gatatttgca aagtgattaa
     8641 acaaaggtag ttttgataat gacatataga cctcctaatg atataattct cctatatttt
     8701 atcataaaaa taata
//
LOCUS       DAPDIM010000090         8661 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000090 DAPDIM010000000
VERSION     DAPDIM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8661
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.090"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            186..1271
                     /locus_tag="RFE25_002511"
     CDS             186..1271
                     /locus_tag="RFE25_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDU2817544.1"
                     /translation="MLNKVWFRTGIALIMLFILIKLFMEVHEVFTPIATIIGSVFLPF
                     LISGFLFYICLPFQNLLEKVGFPRWASITTIMLALFAIIGLIVAFVAPIIISNINNLI
                     SQTPALQKEAEQIIKFALAQMDKLPEDVTSRITNMVKSMGDGVTNILSNSLQYITSLI
                     STIFLLIMVPFFLIYMLKDHEKFIPAVAKFFKGERKVFFVDLLTDLNFTLKSYIQGQV
                     TVSVILGIFLYIGYSIIDLPYIPLLVLFAGVANLIPFLGSWLSFAPAAILGIIDSPTT
                     FIWVCIITLIAHQLEGNIITPNVMGKSLSIHPLTIIVVILAAGDLGGFTLVLIAVPLY
                     AVLKTVVSNIFKYRQRIIDKANSNVKD"
     gene            complement(1468..2238)
                     /gene="fabI"
                     /locus_tag="RFE25_002512"
     CDS             complement(1468..2238)
                     /gene="fabI"
                     /locus_tag="RFE25_002512"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDU2817545.1"
                     /translation="MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERS
                     RKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVFHSIAFANMEDL
                     RGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVM
                     GVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLK
                     RNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK"
     gene            complement(2516..4360)
                     /locus_tag="RFE25_002513"
     CDS             complement(2516..4360)
                     /locus_tag="RFE25_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monovalent cation:proton antiporter family
                     protein"
                     /protein_id="HDU2817546.1"
                     /translation="MEFLSLVIVVLAAFLTPIIVNRLNINFLPVVVAEILMGIVIGNS
                     FLNIVERDSILNILSTLGFIFLMFLSGLEIDFKAFKKDKRARQGQNDDESSIPGHLNL
                     ALTVFAFIMIISILLAYVFKWLGLVDDVLLMVIIISTISLGVVVPTLKEMNIMRTTIG
                     QFILLVAVLADLVTMILLTVYGAINGQGGSTIWLIGILVVFTAISYILGVQFKRMSFL
                     QKLMDGTTQIGIRAVFALIILLVALAEGVGAENILGAFLAGVVVSLLNPDEEMVEKLD
                     SFGYGFFIPIFFIMVGVDLNIPSLIKEPKLLIIIPILIVAFIISKLIPVMFIRRWFDM
                     KTTIASAFLLTSTLSLVIAAAKISERLNAISAETSGILILSAVITCVFVPIIFKKLFP
                     VPDEFNRKIEVSLIGKNQLTIPIAQNLTSQLYDVTLYYRKDLSDRRQLSDDITMIEIA
                     DYEQDVLERLGLFDRDIVVCATNDDDINRKVAKLAKAHQVERVICRLESTTDDTELVD
                     SGIEIFSSYLSNKILLKGLIETPNMLNLLSNVETSLYEIQMLNYKYENIQLRNFPFGG
                     DIIFVRIIRNNESIVPHGDTQLRYGDRLIVTGAKEYVDELKQELEFYF"
     gene            complement(4370..5755)
                     /gene="mgtE"
                     /locus_tag="RFE25_002514"
     CDS             complement(4370..5755)
                     /gene="mgtE"
                     /locus_tag="RFE25_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDU2817547.1"
                     /translation="MSMNTDEKERVQEELYDETLLDQYLENDDIDQFRDEFLALHTYE
                     QSEYFEDTTDENRQKIFQYLSPEEVANFFDQLDIDDDEYELLFDKMNATYASHILEEM
                     SYDNAVDILNELTKPKVASLLTLMNKDDANEIKALLHYDEDTAGGIMTTEYLSLKAHT
                     PVKEALLLVKAQAPDAETIYVIFVVDDDGKLVGVLSLRDLIVAENDAYIEDIMNERVI
                     SVNVADDQEDVAQVMRDYDFMAVPVIDYQEHLLGIITIDDILDVMDEEASEDYSRLAG
                     VSDIDSTNDSIIKTALKRLPWLIILTFLGMITATILGRFEKTLENVALLAAFIPIISG
                     MSGNSGTQSLAVSVRNITTGEINEQSKFRIALREAGSGVLSGVVCSTILFTIIVAIYH
                     QPLLALIVAGSLTCAMTVGTFVGSMIPLLMNKLNIDPAVASGPFITTINDIISMLIYF
                     GLATSFMAYLI"
     gene            complement(5776..6630)
                     /locus_tag="RFE25_002515"
     CDS             complement(5776..6630)
                     /locus_tag="RFE25_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDU2817548.1"
                     /translation="MKFKYHISQQETVKAFLARHDFSKKTVSAIKNNGALIVNDEPVT
                     VRKQLMPNDILEIHLPREIPSVNLIPYARKLEVLYEDAFIIIVTKPNNQNCTPSREHP
                     HESLIEQVLYHCQEHGENINPHIVTRLDRNTTGIVIFAKYGHIHHLFSKVNLKKIYTC
                     LVYGKTHTSGIIEANIRRSKDSIITREVASDGKYAKTSYEVINQNDKYSLCKVHLHTG
                     RTHQIRVHFQHIGHPIVGDSLYDGFHDKIHGQVLQCTQIYFVHPINKNNIYITIDYKQ
                     LLKLFNQL"
     gene            complement(6627..7436)
                     /locus_tag="RFE25_002516"
     CDS             complement(6627..7436)
                     /locus_tag="RFE25_002516"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HDU2817549.1"
                     /translation="MRYTILTKGDSKSNALKHKMMNYMKDFRMIEDSENPEIVISVGG
                     DGTLLQAFHQYSHMLSKVAFVGVHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPL
                     LEIIMRYNDNGYETRYLALNEATMKTENGSTLVVDVNLRGKHFERFRGDGLCVSTPSG
                     STAYNKALGGALIHPSLEAMQITEIASINNRVFRTVGSPLVLPKHHTCLISPVNHDTI
                     RMTIDHVSIKHKNVNSIQYRVANEKVRFARFRPFPFWKRVHDSFISSDEER"
     gene            complement(7453..8088)
                     /locus_tag="RFE25_002517"
     CDS             complement(7453..8088)
                     /locus_tag="RFE25_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDU2817550.1"
                     /translation="MNQWDQFLTPYKQAVDELKVKLKGMRKQYEVGEQASPIEFVTGR
                     VKPIASIIDKANKRQIPFDRLREEMYDIAGLRMMCQFVEDIDVVVNILRQRKDFKVIE
                     ERDYIRNTKESGYRSYHVIIEYPIETLQGQKFILAEIQIRTLAMNFWATIEHTLRYKY
                     DGAYPDEIQHRLERAAEAAYLLDEEMSEIKDEIQEAQKYYTQKRSKKHEND"
     gene            complement(8105..8452)
                     /locus_tag="RFE25_002518"
     CDS             complement(8105..8452)
                     /locus_tag="RFE25_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817551.1"
                     /translation="MRLYINEIKIKDNILYCYTEDSIKGLSEVGQMLVDSDNYAFAYT
                     LDDGKAYAYLIFVQETWTMLHENTTKKIIINDELELTEFHQELTYILDNIKGNNNYGK
                     EFVATVEETFDIE"
BASE COUNT         2845 a         1573 c         1199 g         3044 t
ORIGIN      
        1 gtttgatcca attgcagact tacgaatcat tgaaaagtct cacaaactat tgaaagtaaa
       61 tatcttaaaa tagaaagtga atggttaatt taagtatatt taaaaaatat taaccttttt
      121 aagcactgct atttaggata tactaaataa taactaagtt tagaaaaata ggaggaacat
      181 cgtttatgtt aaacaaggtt tggttccgaa ctggcatcgc tctgattatg ctgttcattc
      241 tcatcaaact atttatggaa gtgcacgaag tatttactcc aatagctaca atcatcggtt
      301 ctgtatttct tccattttta attagtggtt ttttatttta tatctgtcta ccttttcaaa
      361 acttacttga aaaagtcggt tttccaagat gggctagtat aacaacaatc atgttagctt
      421 tgtttgctat tatcggctta attgttgcgt ttgttgcacc aatcatcatt tcaaatatca
      481 acaatttaat tagtcagaca cctgccctac aaaaagaagc agagcaaatt attaaattcg
      541 cactagctca aatggataaa ttacctgaag atgtaacaag tagaattaca aatatggtta
      601 aatcaatggg tgatggcgtt actaatattt tatctaattc attacagtac attacatcat
      661 taatttcaac catcttctta ttgattatgg ttccattctt cttaatttat atgttaaaag
      721 accatgaaaa atttatccca gctgttgcta aatttttcaa aggtgaacgt aaagtatttt
      781 tcgtagattt attaactgat ttaaacttta cattaaaatc ttacattcaa ggtcaagtaa
      841 ctgtcagtgt tattttaggt atattcttat atatcggtta ttcaattatt gacttaccat
      901 atattccttt attagttcta tttgctggtg tcgcaaactt aattcctttc ttaggttcat
      961 ggttatcatt tgcacctgca gcaatactcg gtattataga tagtcctact acatttatat
     1021 gggtttgtat cattacatta attgcacacc aacttgaagg taatatcatt acgccaaatg
     1081 taatgggtaa atctttaagt atccatcctt taacaattat cgttgttatt ttagcagcag
     1141 gagatttagg tggctttaca ttagttctga ttgcagtgcc attatatgct gtacttaaaa
     1201 cggttgttag taatattttc aaataccgcc aacgcattat tgataaagca aacagtaatg
     1261 ttaaggacta attctgtgga tgtcttttaa gaatataaga tactatctcc tcaaaagttg
     1321 aaactacagc ttttgaggag atttttttgt gcataaaaaa aatcagtcag atgaaatatc
     1381 aaataatttt ccatcagtcc gattattata aaagcaaaaa agctttgctc acatatatga
     1441 taacgtgaac aaagctgttg aatgatatta tttaattgcg tggaatccgc tatctacatg
     1501 aatattttca cctgtaacgc cacttgataa gtcacttaat aagtaagccg ctgttttacc
     1561 tacttctact tgatcaacgt tacgttttaa aggtgcacgc tcttcgattt ctttaagaat
     1621 tgtattgaaa ccacccacac cttttgcact taatgtacgg attggaccag ctgaaattgc
     1681 attaacgcga atattatcag gacctaagtc taatgctaaa tatttaacat ttgcttctaa
     1741 gctcgcttta gcaacaccca tcacattata attttgaact gcgaattcgc cacctaaata
     1801 tgttgttgca acaatgctac caccttctgg cattaatttt ttagcttcat gagccacaat
     1861 tgttaatgag taagaactaa tgtcttgagc taacaagaag ccttcacgtg aagtttcaga
     1921 aaagcgtccg cgtaagtctt ccatattagc aaatgcgatt gaatgaaata caccatcaat
     1981 attgccaaca tctttaccaa tttgctcaaa accattaata acctcttcat cgctttgaac
     2041 atcaatttga tataagtgcg cttctggttg atttaattgt tctaataatt tttcaagctc
     2101 tttacggcta cgttctttac ggtaagtaaa tactaattta gcacctaatt gatctaaaac
     2161 tttagcgaca ccaaaagcaa tactacgctt attagcgatt cccatgatga catatgtttt
     2221 gttttcaaga tttaacatgt aagataactc cttataataa ttaatttaac ggatagaata
     2281 tctaatccca gttttaacta actttttatt cgtcaataca ttttaacact attatgactt
     2341 tttaataaag ttatttaaac gtattacaac gataaatgtt tgatttagtc ctttctgtat
     2401 caaacttgat ttacgtaaaa agcatttatt tatcaaaatc atatacatac tagcatttta
     2461 aaatcattaa ttttacgtcg tactaaaata cgtctgcatt ttaatatcat tattgttaaa
     2521 aataaaattc taactcttgc ttcaattcat caacgtattc tttagcaccg gtaacaatta
     2581 agcgatctcc atatcgcaat tgtgtatctc catgcggaac aatcgactca ttattacgga
     2641 taatacgcac gaagatgatg tctcctccga atgggaaatt acgtaattga atattttcat
     2701 atttataatt taacatttga atttcatata gtgacgtttc aacattactt aataaattca
     2761 acatgttagg tgtttcaatt aaacctttta ataagatttt attacttaag tagctactga
     2821 aaatttcaat acctgaatca actaactctg tatcgtccgt tgtgctttca agtctgcaaa
     2881 tgacacgctc aacttgatgt gctttggcta atttagcaac ttttcggtta atatcatcgt
     2941 cattcgtagc acaaacaact atgtctcggt caaacagacc tagtcgttct aaaacatctt
     3001 gttcataatc agcaatttct atcatcgtga tatcatctga caattgacga cgatcactca
     3061 agtctttgcg ataatataat gtcacgtcat ataactgaga tgttaaattt tgcgctatag
     3121 gaatcgttaa ttgattttta ccaattaaac taacttcaat tttacggtta aactcatctg
     3181 gaactggaaa cagttttttg aaaataatcg gaacgaatac acatgtaatg actgcgctta
     3241 aaattaatat acctgacgtt tcagctgaaa tagcatttaa tctttctgaa attttggctg
     3301 cagctatcac gagcgataat gttgatgtta ataaaaatgc tgatgcaatc gttgttttca
     3361 tatcaaacca acgtcgaata aacatgactg gaattaattt tgaaatgata aatgcaacga
     3421 ttaaaatcgg tatgataatt agtaatttcg gttctttaat taatgaaggt atgtttaaat
     3481 ctacaccaac cattataaag aaaataggaa taaagaaccc ataaccaaat gagtctaact
     3541 tttcaaccat ttcttcatct ggatttaata atgaaacaac gacacctgct aagaatgcac
     3601 ctaatatatt ttctgcgcca actccctctg ctagggctac taataatatt attaatgcaa
     3661 ataccgcacg aataccgatt tgcgtcgtac catccatcaa tttttgtaaa aatgacattc
     3721 ttttaaattg aacacctaaa atatatgaaa ttgctgtgaa aacaactaat atacctatta
     3781 accatattgt actgccgcct tgaccattga ttgcgccata gaccgttaat aaaatcatag
     3841 ttactaagtc cgcaagtact gctactaata ggataaattg ccctatagtt gttctcataa
     3901 tattcatttc ttttaaagtt ggaacaacta cgcctaagga aatagttgaa atgataatga
     3961 ccattaataa cacatcatcc actaatccaa gccatttaaa tacatacgct aaaagaatcg
     4021 aaataatcat aataaatgca aatacagtta acgctagatt aagatgccct ggaattgagg
     4081 attcatcatc attttgtcct tgacgtgcgc gtttatcttt tttaaaagct ttaaaatcaa
     4141 tttctaaacc acttaaaaac attaaaaaga taaagcctaa cgttgataaa atatttagaa
     4201 ttgaatccct ttctactata tttagaaatg aatttccaat cacaatcccc atcaaaattt
     4261 ctgcaacaac aactggcaag aaattaatat ttaatcgatt gacaattatt ggagttaaaa
     4321 acgctgctaa aacaacaata actaaagata aaaactccat aactcctcct taaattaagt
     4381 aagccataaa tgatgtagct aaaccaaaat aaatcaacat actaataata tcattaattg
     4441 ttgtaataaa tggtccacta gccactgctg gatcgatatt taatttattc atcaataatg
     4501 gaatcatcga acctacaaac gtccccaccg tcatcgcaca agttaaactt cctgcaacga
     4561 ttaatgctaa aagtggctga tgatatattg caacaataat tgtaaataat attgttgaac
     4621 atacaacgcc cgataataca ccacttcccg cttctcttaa tgcaattcta aatttacttt
     4681 gctcattaat ttcccctgtc gtaatgttac gaactgaaac ggctaaagat tgtgtacctg
     4741 aatttcctga cataccacta ataataggaa taaacgctgc gagtagcgct acattttcta
     4801 atgttttttc aaatctccct aaaattgtcg cagtaatcat tcctaaaaat gttaaaataa
     4861 tcaaccatgg taaacgtttt aatgctgttt taatgattga atcattagtc gaatcgatat
     4921 ctgatacccc ggctaaacga gagtagtctt cactagcctc ttcatccata acgtctaaaa
     4981 tatcatcaat cgtgatgata ccaagcaaat gttcttggta atctataaca ggtacagcca
     5041 tgaaatcata gtctctcata acttgagcaa catcttcttg gtcgtctgct acattcacac
     5101 taatgacacg ttcattcata atatcttcaa tataagcatc attttcagct acaattaaat
     5161 ctcttagtga taaaacacct actaatttac catcatcatc aacgacaaat ataacatata
     5221 ttgtttctgc gtctggcgct tgcgctttga ccaataataa cgcttcttta acaggcgtat
     5281 gcgctttaag tgataaatac tccgtcgtca taataccgcc ggccgtatcc tcatcatagt
     5341 gaagtaatgc tttgatttca ttcgcgtcat ctttattcat caatgttaaa agactagcaa
     5401 cttttggttt agtcaactca tttaaaatat ctactgcatt atcgtatgac atttcttcta
     5461 atatgtgact tgcgtatgtc gcattcattt tatcaaatag caactcatat tcatcgtcat
     5521 caatatctaa ttgatcaaag aaatttgcaa cctcttcagg tgataaatat tgaaaaatct
     5581 tttgtctatt ttcatcggta gtatcttcaa aatactcact ttgttcatat gtgtgtaatg
     5641 ctagaaattc atctctaaat tgatcaatat catcattttc taagtattga tctaataatg
     5701 tctcatcata taattcctct tgaacacgct ctttttcatc tgtgttcatt gacatactta
     5761 caccccctgt gtgaattaga gttgattgaa taatttaagt aattgcttat aatcaattgt
     5821 aatataaata ttgttcttat tgattggatg aacaaaatat atttgcgtac attgcagtac
     5881 ttgaccatga attttgtcat gaaaaccatc atacaaagaa tctcccacaa ttggatgccc
     5941 aatatgttga aaatgtacac gaatttgatg tgtacgtccc gtatgcaaat gaactttgca
     6001 taaactgtat ttatcattct gatttattac ttcataagat gttttagcgt atttaccatc
     6061 cgaggcaact tctctagtta taatactatc ctttgaccgt ctaatattag cttcaataat
     6121 accagatgta tgggttttgc catatacaag gcaagtatat atttttttca agtttacttt
     6181 agaaaataaa tgatggatat gtccatattt agcgaatatc acaataccag ttgtattacg
     6241 atctagacgc gtaacaatat gtgggttaat attttcacca tgttcctgac aatgatatag
     6301 tacttgttcg attaaacttt catgaggatg ttctctcgaa ggcgtacaat tttgattgtt
     6361 tggtttagta actatgatga taaaagcatc ttcatacaat acttctagct tacgagcata
     6421 aggtattaaa ttaacactcg gtatttctcg cggtaaatga atttctaata tatcatttgg
     6481 cattaattgc ttacgtactg tgactggttc atcattaaca attaaagcgc cattattttt
     6541 aatggcgctc actgtcttct tagaaaaatc atgtcgtgct aaaaaagctt taacagtttc
     6601 ttgttgtgat atatgatact taaatttcat cgttcttcat cacttgatat gaaagaatcg
     6661 tgtacacgtt tccagaacgg gaatggtcta aaacgtgcaa acctcacttt ttcatttgct
     6721 acacggtatt gtattgaatt aacattttta tgtttgatac taacatgatc tatcgtcatt
     6781 ctaatggtat catgattaac tggtgatatt aaacatgtat gatgctttgg taatacaagt
     6841 ggtgatccta ccgttctaaa cacacgatta tttattgagg caatttctgt aatttgcatt
     6901 gcttcaagtg aaggatgtat cagtgcgcca cctagcgctt tgttataagc cgttgaaccc
     6961 gaaggtgttg atacacataa tccatcgcct ctaaatcgct caaagtgttt ccctcttaag
     7021 ttaacatcca caacaagtgt tgagccattt tcagttttca tcgttgcttc atttaatgct
     7081 aaataccttg tttcatagcc gttgtcgttg tatctcataa taatttcaag caatggatat
     7141 tcaatgacct gaaactctga attattaatt tcgatgatta atttttcaac ttcatgaggt
     7201 aaccaatccg cataaaatcc taaatgacct gtatgaactc caacaaatgc cacttttgat
     7261 aacatgtggc tatactgatg gaatgcttgt agtaatgtac catcaccacc aactgaaata
     7321 acaatttcag gattttcact atcctcaatc atgcgaaaat ctttcatata gttcatcatt
     7381 ttatgcttta aggcattaga cttggagtca cctttagtta aaattgtata acgcatgatt
     7441 tataacacct cgttaatcat tttcatgttt tttagaacgt ttttgcgtgt aatatttttg
     7501 agcttcctga atttcatctt taatttcaga catctcttca tcaagtaaat acgctgcttc
     7561 tgccgctctt tccaaacgat gttgaatttc atccggataa gcaccatcat atttatatcg
     7621 taaagtatgt tcaatcgttg cccagaaatt cattgctaat gtacgaatct gaatctcagc
     7681 caatataaat ttttggcctt gtaatgtttc aattggatat tcaataatga catgatatga
     7741 gcggtaacca ctttctttag tgttacgaat ataatctcgt tcttcaatta ctttaaaatc
     7801 ttttctttgt cttaaaatat tgacgacaac atcaatatct tctacaaatt ggcacatcat
     7861 tcttaaacca gcgatatcgt acatttcttc tcttaaccta tcaaatggta tttgtcgttt
     7921 gtttgcctta tctataatac tagcgatcgg tttaacacga ccagtaacaa attctattgg
     7981 cgacgcttgt tcaccaactt catattgttt gcgcatgcct ttaagtttca ctttcaactc
     8041 atcaaccgct tgcttataag gtgttaagaa ctgatcccat tgattcatag tgcttcaccc
     8101 cgctttattc aatgtcgaat gtttcttcaa cggttgcaac aaattcctta ccataattat
     8161 tattcccttt tatgttgtct aaaatataag taagttcttg gtggaattca gtcaattcta
     8221 gttcatcatt gataataatt tttttagtcg tgttttcatg caacatcgtc catgtttctt
     8281 gtacgaaaat gagataagca tacgctttac catcatctaa tgtatacgca aaggcataat
     8341 tatcactatc aacgagcatt tgtcctactt cagataatcc tttaatagaa tcttctgtat
     8401 aacaataaag tatgttatct ttaattttaa tttcattaat atataaacgc atgcttaatc
     8461 ctcctcttat tccataacat tttaacacaa ttcaataata caaaacactt acgaacacta
     8521 tttttaatgg tcaaattaac attgataata gataaaggaa attgctttta aaattcaact
     8581 ttgtcattca taatatagtt aagataaatt gaatttgata cgaggtgtat acatatcatg
     8641 gcaacaaatc atgaaataga a
//
LOCUS       DAPDIM010000091         8618 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000091 DAPDIM010000000
VERSION     DAPDIM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8618
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.091"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(336..536)
                     /locus_tag="RFE25_002519"
     CDS             complement(336..536)
                     /locus_tag="RFE25_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDU2817552.1"
                     /translation="MNNGTVKWFNAEKGFGFIEREDGSDVFVHFSAIAEDGYKSLEEG
                     QKVEFDIVEGDRGEQAANVVKM"
     gene            complement(893..1579)
                     /locus_tag="RFE25_002520"
     CDS             complement(893..1579)
                     /locus_tag="RFE25_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDU2817553.1"
                     /translation="MTEYLLSAGICMAIVSILLIGMAISNVSKGQYAKRFFFFATSCL
                     VLTLVVVSSLSSSANASQTDNGVNRSGSEDPTVYSATSTKKLHKEPATLIKAIDGDTV
                     KLMYKGQPMTFRLLLVDTPETKHPKKGVEKYGPEASAFTKKMVENANKIEVEFDKGQR
                     TDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKPNNTHEQLLRKSEAQAKKEKLNI
                     WSEDNADSGQ"
     gene            complement(1920..2441)
                     /locus_tag="RFE25_002521"
     CDS             complement(1920..2441)
                     /locus_tag="RFE25_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817554.1"
                     /translation="MKRKVLVLTMGVICATQLWHSNHANALVTESVETNFVVKDSDNK
                     NILQTHTEITTQEKFSIVEKSQLNKLKALSNDNYIEYDLHTNQTGIKKGWLYGYSEIG
                     SSHFTDRDKRVIRRDHVKEAQSLINDYKDTQSYEDLAKATAKVSTLSQSHQNYLNKQI
                     DKVNNKIEKTEKR"
     gene            complement(2776..3798)
                     /gene="emp"
                     /locus_tag="RFE25_002522"
     CDS             complement(2776..3798)
                     /gene="emp"
                     /locus_tag="RFE25_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular matrix protein-binding adhesin
                     Emp"
                     /protein_id="HDU2817555.1"
                     /translation="MKKKLLVLTMSTLFATQLINSNHAKASVTESVDKKFVVPESGIN
                     KIIPAYDEFKNSPKVNVSNLTDNKNFVVSEDKLNKIVDSSAASKIVDKNFAVPESKLG
                     NIVPEYKEINNRVNVATNNPASQQVDKHFVAKGPEVNRFITQNKVNHHFITTQTHYKK
                     VITSYKSTHVHKHVNHAKDSINKHFIVKPSESPRYTHPSQSLIIKHHFAVPGYHAHKF
                     VTPGHASIKINHFCVVPQINSFKVIPPYGHNSHRMHVPSFQNNTTATHQNAKVNKAYD
                     YKYFYSYKVVKGVKKYFSFSQSNGYKIGKPSLNIKNVNYQYAVPSYSPTHYVPEFKGS
                     LPAPRV"
     gene            complement(4151..5653)
                     /gene="vwb"
                     /locus_tag="RFE25_002523"
     CDS             complement(4151..5653)
                     /gene="vwb"
                     /locus_tag="RFE25_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001628779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="von Willebrand factor binding protein Vwb"
                     /protein_id="HDU2817556.1"
                     /translation="MKNKLLVLSLGALCVSQIWESNHASAVVSGEKNPYVSKALELKD
                     KSNKSNSYENYRDSLESLISSLSFADYEKYEEPEYEKAVKKYQQKFMAEDDALKNFLN
                     EEKKIKNADISRKSNDLLGLTHERYSYIFDTLKKNKQEFLKDIEEIQLKNSDLKDFNN
                     TEQHNADVEINNLENKVLMVGYTFYNTNKDEVEELYSELDLIVGEVQDKSDKKRAVNQ
                     RMLNRKKEDLEFIIDKFFKKIQQERPESIPALTSEKNHNQTMALKLKADTEAAKNDVS
                     KRSKRSLNTQNNKSTTQEISEEQKAEYQRKSEALKERFINRQKSKNESVVSLIDDEDD
                     NENDRQLVVSAPSKKPTTPTTYTETTTQVPMPTVERQTQQQIVYKTPKPLAGLNGESH
                     DFTTTHQSPTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKRE
                     HVREAQKLVDNYKDTHSYKDRLNAQQKVNTLSEGHQKRFNKQINKVYNGK"
     gene            complement(5874..>8618)
                     /gene="clfA"
                     /locus_tag="RFE25_002524"
     CDS             complement(5874..>8618)
                     /gene="clfA"
                     /locus_tag="RFE25_002524"
                     /inference="COORDINATES: protein motif:HMM:NF021909.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin clumping factor ClfA"
                     /protein_id="HDU2817557.1"
                     /translation="TKTSSNTNNGETSVAQNPAQQETTQSSSTNATTEETPVTGEATT
                     TTTNQANTPATTQSSNTNAEELVNQTSNETTSNDTNTVSSVNSPQNSTNAENVSTTQD
                     TSTEATPSNNESAPQNTDASNKDVVSQAVNPSTPRMRAFSLAAVAADAPAAGTDITNQ
                     LTDVKVTIDSGTTVYPHQAGYVKLNYGFSVPNSAVKGDTFKITVPKELNLNGVTSTAK
                     VPPIMAGDQVLANGVIDSDGNVIYTFTDYVDNKENVTANITMPAYIDPENVTKTGNVT
                     LTTGIGTNTASKTVLIDYEKYGQFHNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVVL
                     PALTGNLIPNTKSNALIDAKNTDIKVYRVDNANDLSESYYVNPSDFEDVTNQVRISFP
                     NANQYKVEFPTDDDQITTPYIVVVNGHIDPASTGDLALRSTFYGYDSNFIWRSMSWDN
                     EVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGS
                     DSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS
                     ASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS
                     DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGSNNNVVPPN
                     SPKNGTNASNKNEAKDSKEPLPDTGSEDEANTSLIWGLLASLGSLLLFRRKKENKDKK
                     "
BASE COUNT         2466 a         1496 c         1313 g         3343 t
ORIGIN      
        1 aagtagtaag atattatgcg atgtggtatc ctattattgt taaacatttt gagtgtttaa
       61 cattacttct tgttatcgcc atatacagac tttaattctc gtcattatta aagttctgta
      121 ttggcgcttt ttttattcaa aatcaaaagt cggacagatg aaaagtaaaa aacttttcca
      181 tcaattcgat ttattataga accattatat attgttagat ctccacaatt tattggacaa
      241 aaaaataacg gctagtgctt ttaccacacc aactgttatc gatttaaagc ataaaaaaac
      301 agccctataa taaggactgt ttgaataagt taaaattaca ttttaactac gtttgcagct
      361 tgctcgccac ggtcgccttc aacgatgtcg aattcaactt tttggccttc ttctaatgat
      421 ttgtatccat cttcagcgat tgctgagaag tgtacgaata cgtcgctacc atcttctctt
      481 tcgatgaaac caaaaccttt ttctgcatta aaccatttaa ctgtaccgtt attcatattg
      541 aatacctccg tcgtgctttt gcactaaata ttttgtaaca aattcataaa tgaaaaggag
      601 aatattctat ataaataact cacatttttc ttcacgctct ttattactta actttcatta
      661 tacactttta aatatagaag taaagcatta ttttattttc tgtgataata cacattgaac
      721 tatatagtaa cattccattt taatactaaa tttaaaattt ttattttcta atattaaata
      781 cacttgcttt tgatactatt tactttttta attctgaatt gataataaat catatcgtga
      841 tctaaaaatt ataaaagggc cactagcagc agtgacactt ttacaatgag cattattgac
      901 ctgaatcagc gttgtcttcg ctccaaatat ttaatttctc ttttttcgct tgtgcttcac
      961 tttttcttaa aagttgttca tgtgtattgt taggtttata aacataagca actttagcca
     1021 agccttgacg aactaaagct tcgtttacca tttttccatc agcataaata tacgctaagc
     1081 cacgtccata tttatcagtt ctttgacctt tgtcaaactc gacttcaatt ttatttgcat
     1141 tttctaccat ttttttcgta aatgcacttg cttcagggcc atatttctct acaccttttt
     1201 taggatgctt tgtttcaggt gtatcaacta ataatagtct gaatgtcatt ggttgacctt
     1261 tgtacattaa tttaaccgta tcaccatcaa tcgctttaat taatgtcgca ggttctttat
     1321 gtaatttttt agttgaagtt gcactatata ctgttggatc ttcagaacca cttctattta
     1381 cgccgttatc tgtttgtgat gcatttgctg agctacttag acttgaaact acaactaaag
     1441 ttaacactaa gcaactagta gcgaaaaaga aaaacctctt tgcgtattgc cctttcgaaa
     1501 cattactgat agccatccct ataagtaata ttgaaacaat tgccatacat atgccagcac
     1561 ttaataagta ttctgtcata actaacacct ctttcttttt agttaatttt aatattaaac
     1621 gttaattaat tataattcta catttttaca attaattaat aaaaatttaa taattataat
     1681 aaaataacta tacttacttt tatgtatttt ctatatttta ggtgtcagaa cttatatatt
     1741 tagccttatt tgtaaaatta aaaagcctac aacatgaatc gttgcagact atcatatcga
     1801 gacaaagagg tttattagcg tctctatatc tatgcggaat ttgaaaagat tatttattat
     1861 atttacgggg ataaattgtc atttaaaaac gagatgtata acttataatt tactttggat
     1921 tagcgttttt cagttttctc tattttatta ttcactttat caatttgttt atttaaataa
     1981 ttttggtgag actgactaag tgtacttact tttgcagttg ccttagcgag atcttcatag
     2041 ctttgtgtat ctttataatc gttaattaag ctttgtgctt ctttaacatg atcacgtcta
     2101 ataacgcgtt tgtcacggtc tgtgaaatgt gatgagccaa tttcactata accatataac
     2161 caaccttttt taatacctgt ttgattagta tgtaaatcat attctatgta gttgtcatta
     2221 gatagtgctt ttaatttatt taattgactc ttttctacta ttgaaaattt ctcctgagta
     2281 gtaatttcag tatgggtttg taaaatattt ttattatccg aatcttttac aacaaaatta
     2341 gtttcaacac tctctgtcac taatgcgttt gcgtgattag aatgccataa ttgagttgca
     2401 caaattacac ccattgttag tactagtact ttccttttca tttatttatg ctcccttatt
     2461 tgctttgatt gtaaaaccga ctttttcacc ctgttttctt cgccattgaa aattatatac
     2521 caatatttta gaaacaataa ttaacttgcg atgaacaaac tattaacaat aatcttgagt
     2581 cttatattta tcttaattaa taatatattt atttaagatt atgttacttc caactttcaa
     2641 agtagaaaaa cggtataatt tgttgatggg tgtttattga taaactgcaa aaaatacagc
     2701 ctacaaccac atagattgta gactatattt aaaataatag gtatttatca tatctcgtaa
     2761 acttagtgcc aatttttata ctcgtggtgc tggtaagcta cccttaaatt caggaacgta
     2821 gtgtgtaggg ctataacttg gaacagcata ttgataattt acatttttga tatttaatga
     2881 tggtttccca attttataac catttgattg tgaaaatgag aaatatttct tcacaccttt
     2941 aactacttta taagaataga agtatttata gtcatatgct ttatttactt tagcattttg
     3001 atgtgttgct gttgtgttat tttggaaact tggtacatgc atacgatgtg aattgtgacc
     3061 atatggtgga attaccttga aactatttat ttgtggcaca acacaaaagt gattaatttt
     3121 aatgctagca tgccctggtg taacaaattt atgcgcgtga tatccaggaa ctgcaaaatg
     3181 atgcttgata attaaagatt gagatggatg tgtatatcta ggcgattctg atggtttaac
     3241 aataaagtgt ttattaatag aatcctttgc atgatttaca tgtttatgta catgtgttga
     3301 tttgtatgaa gtaataactt tcttgtagtg ggtttgcgta gtaatgaagt ggtggtttac
     3361 tttgttttgc gtaataaatc tatttacttc tgggccttta gcaacaaaat gcttatcaac
     3421 ttgttgtgaa gctggattgt ttgttgctac attcacgcga ttattgattt ctttgtactc
     3481 tggtacaatg tttcctaact ttgattctgg tacggcaaag tttttatcta caattttact
     3541 agctgccgat gaatctacaa tcttattcaa tttgtcttca gaaactacaa agtttttatt
     3601 gtcagttaaa ttactaacat ttacttttgg cgaattctta aattcatcgt aagctggaat
     3661 aattttatta attcctgatt ctggaactac aaattttttg tcaacactct ctgtcactga
     3721 tgctttagcg tgatttgaat tgataagttg tgtagcaaat agcgtgctca tagttaaaac
     3781 taataatttc tttttcatct gttatttctc ctttatatag actcaatatt ataaccaata
     3841 taatttccct gttatattca ctaacagcat tatataccag aattttcagt ataataatta
     3901 acttgaagta aacgttgtct taacattttt attgtttttc agcttaaaat taattattga
     3961 tattgatagt taagcataat aattttttcg taatataaag tgaaaaaagt aatagtccac
     4021 acctgtttag aatgtggact atactagatt gcatcattga aatgatgact ttgatattat
     4081 ttattgctag tttaaaatgt tgttattttt acgacaaact cattatttgc tttgcagcca
     4141 tgcattaata ttatttgcca ttgtatactt tattgatttg tttattaaaa cgtttttgat
     4201 gaccttcact taaagtattt actttttgtt gtgcatttaa tcggtcttta taactatgtg
     4261 tatctttata attatcaact aacttttgag cttctctaac gtgttcacgc ttgattacac
     4321 gcttctcacg ttcagttaga tgagaagaat caatttgact tataccaacc agtgatcctg
     4381 attttctacc aggtaaagca gacgtttctt caaattcaac aacattatta tgcgtatgat
     4441 ttgaagttgt tggtgattga tgcgttgttg tgaaatcatg actttcacca tttaatccag
     4501 ctaatggttt tggtgttttg taaacgattt gttgctgagt ttgacgctca actgtaggca
     4561 ttggtacctg agtcgttgtt tcagtatatg tagtcggtgt tgttggtttc tttgatggcg
     4621 cagaaaccac aagttgcctg tcgttttcgt tgtcgtcttc gtcatcgatt agtgaaacca
     4681 cagactcatt tttagatttt tgtctgttta taaatctttc ttttaatgcc tctgactttc
     4741 tttgatattc agctttttgt tcttcagaaa tttcttgtgt tgtagattta ttattttgag
     4801 tatttaaact tcttttactt ctttttgata cgtcattttt agcagcttct gtatctgctt
     4861 ttaactttaa tgccatagtc tgattatgat ttttttcact agttaatgct ggtatactct
     4921 ctggacgttc ttgttgaatt tttttaaaaa atttatctat aataaattct aaatcctctt
     4981 tttttctatt taacatcctt tgatttactg ctcttttttt atccgactta tcttgaactt
     5041 ctccaacaat caaatctaac tcactatata attcttcaac ttcgtcctta tttgtattat
     5101 agaatgtata ccctaccatt aatactttat tttctaaatt gtttatttct acgtcggcat
     5161 tatgttgctc tgtattgtta aagtccttta aatcactatt tttcagttgt atttcttcaa
     5221 tatcttttaa aaactcttgt ttatttttct ttaatgtatc aaaaatataa gaatatcttt
     5281 catgtgttaa acctaataaa tcattcgatt ttctgctaat atctgcattt tttatcttct
     5341 tttcttcatt taaaaaattt tttaatgcat catcttcagc cataaatttt tgttgatatt
     5401 tttttacagc cttttcatat tctggctctt catatttttc ataatcagca aaagataatg
     5461 atgaaatcaa actttctaaa ctatctctat aattttcgta agaattggat ttattacttt
     5521 tatctttcaa ttctaaagct tttgatacat atggattctt ctccccagaa accactgcac
     5581 tcgcatgatt actttcccaa atttgtgata cacataatgc tcccaatgat aaaactagca
     5641 atttattttt caactgtatt ttctccttaa ttttccctaa ttaacaacct accttacacc
     5701 ctattttttc gccaagccaa attatataac atctaccttt ttaaaataat taactgttga
     5761 tgaattaatt attaattata ttcaaacaat atatttggaa aatccaagta aaaaagccac
     5821 cttttaaggt ggcttcttca tgaatcatat gattaattta atattattat tacttatttc
     5881 ttatctttat tttctttttt tcttctgaaa agtagtaatg aacctaatga tgctaataat
     5941 ccccaaatta gtgacgtatt cgcttcatct tcagaacctg tatctggtaa tggttcttta
     6001 ctatctttag cctcattttt attagaagca ttagtaccat ttttaggtga attaggcgga
     6061 actacattat tgttagaacc tgactcggaa tcgctatttg aatcactgtc tgagtcgttg
     6121 tctgatcctg tgtcactcgt tgaatcggaa tctgaatcac ttgatgaatc ggagtcacta
     6181 cctgagtctg aatcactcgc tgaatccgaa tcgctatctg aatcggagtc actatctgat
     6241 tctgaatcgc tgtctgaatc ggagtcacta tctgattctg aatcgctgtc tgagtctgag
     6301 tcactatctg aatctgaatc actgtctgag tctgagtcac tatctgattc tgaatcgcta
     6361 tctgaatctg aatcactcgc tgaatccgag tcactatcgg aatctgagtc actgtcggaa
     6421 tctgaatcgc tatcggaatc tgaatcgctg tctgagtctg agtcactgtc ggaatctgaa
     6481 tcgctatctg agtctgaatc actgtctgaa tctgaatcgc tatctgaatc tgagtcactg
     6541 tctgagtctg aatcgctgtc tgaatctgaa tcgctgtctg aatctgagtc gctatctgag
     6601 tcggaatcgc tatctgagtc ggaatcactg tcggaatctg aatcgctatc ggaatctgag
     6661 tcactgtctg agtcggaatc gctatcggaa tctgagtcac tgtctgagtc ggaatcgcta
     6721 tcggaatctg agtcactgtc tgagtcagaa tcgctgtctg agtcagaatc gctgtctgaa
     6781 tctgagtcgc tatctgagtc ggaatcgcta tcggaatctg agtcactatc tgagtctgaa
     6841 tcgctcgctg agtcggaatc actcgctgaa tctgaatcgc tcgctgaatc tgaatcgctc
     6901 gctgaatctg aatcgcttgc tgaatctgaa tcacttgctg aatctgaatc acttgctgag
     6961 tctgaatcac ttgctgaatc tgaatcactt gctgaatctg aatcacttgc tgaatctgaa
     7021 tcactcgctg agtctgaatc acttgctgaa tctgaatcac tcgctgaatc tgaaccacta
     7081 tctgatgtag aatcactgcc agaatctgaa ccgctatctg aattagaatc gctgccagaa
     7141 tctgaacctg ggtcagaatc tgaatcctct ggaattggtt caatttcacc aggctcatca
     7201 ggttgttcag gaacaactgg tttatcgata ccgtcaccag aacctgatcc gttattaaat
     7261 gctacttcgt tgtcccatga catagatctc catataaaat tagaatcata accataaaat
     7321 gtcgaacgta gtgctaaatc acctgtacta gcaggatcaa tatggccatt aacaactaca
     7381 atatacggtg ttgtaatttg gtcatcgtcc gtaggaaatt ctactttgta ttgattagca
     7441 tttggaaatg aaattctaac ttgattagtt acatcttcaa aatcgctagg attcacataa
     7501 taactttcag ataaatcatt agcattatcg actctataaa ctttaatatc agtgtttttt
     7561 gcatctatta acgcattact ctttgtatta ggaattaaat tacctgttaa ggcaggtaac
     7621 acaacgttat ctccgcttgg attgacataa attgtttggc gatacgtatt atttgtttta
     7681 tcgatttgat caatcgtacc tttaattgat aaattatgga attgtccata tttctcatag
     7741 tcgattaata ctgtcttact agcagtattg gttcctatgc cagttgtcaa tgtcacatta
     7801 cctgtctttg taacattttc agggtcaata taagctggca tagtaatatt agctgttaca
     7861 ttttctttat tatcaacata gtctgtaaat gtataaataa cattaccatc actatcgatt
     7921 acaccatttg ccaatacttg atctccagcc ataattggtg gcactttagc agttgaagtt
     7981 acaccattta agtttaattc tttaggtaca gttattttga atgtgtcacc tttaacagca
     8041 gaattaggca ctgaaaaacc ataattcagt ttgacataac ctgcttggtg cggatacaca
     8101 gtcgtaccag agtcaatagt aactttcaca tctgtcaact gattcgtaat atctgtgcca
     8161 gctgccggtg catctgcagc tactgccgct aaactaaatg ctctcattct aggcgtactt
     8221 ggattaaccg cttgactaac tacatcttta ttacttgcat ctgtattctg tggagctgat
     8281 tcattgtttg aaggtgttgc ttcagttgaa gtatcttgcg ttgttgaaac attttccgca
     8341 tttgtagaat tttgaggtga atttacagat gatactgtat tagtatcatt agaagtcgtt
     8401 tcattacttg tttgattcac taattcctcc gcatttgtat tgcttgattg agttgttgcc
     8461 ggtgtattag cttgattcgt tgtcgtagta gtagcttcac cagttaccgg cgtttcttcc
     8521 gtagttgcat ttgttgatga tgattgtgtc gtttcctgtt gtgctggatt ttgcgccaca
     8581 ctcgtttcgc cattattagt gtttgacgat gttttagt
//
LOCUS       DAPDIM010000092         8479 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000092 DAPDIM010000000
VERSION     DAPDIM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8479
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.092"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            141..1670
                     /gene="aur"
                     /locus_tag="RFE25_002525"
     CDS             141..1670
                     /gene="aur"
                     /locus_tag="RFE25_002525"
                     /EC_number="3.4.24.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloproteinase aureolysin"
                     /protein_id="HDU2817558.1"
                     /translation="MRKFSRYAFTSMAAVTLLSTLSPAALAIDSKNKPANSDIKFEVT
                     QKSDAVKALKELPKSENVKNIYQDYAVTDVKTDKKGFTHYTLQPSVDGVHAPDKEVKV
                     HADKSGKVVLINGDTDAKKVKPTNKVTLSKDDAADKAFKAVKIDKHKAKNLKDKVIKE
                     NKVEIDGDSNKYVYNVELITVTPEISHWKVKIDAQTGEILEKMNLVKEAAETGKGKGV
                     LGDTKDININSIDGGFSLEDLTHQGKLSAFSFNDQTGQATLITNEDENFVKDEQRAGV
                     DANYYAKQTYDYYKDTFGRESYDNQGSPIVSLTHVNNYGGQDNRNNAAWIGDKMIYGD
                     GDGRTFTSLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFL
                     MGEDVYTPGKEGDALRSMSNPEQFGQPAHMKDYVFTEKDNGGVHTNSGIPNKAAYNVI
                     QAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGV
                     E"
     gene            2037..2486
                     /locus_tag="RFE25_002526"
     CDS             2037..2486
                     /locus_tag="RFE25_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDU2817559.1"
                     /translation="MKKSKRLEIVSTIVKKHKIYKKEQIISYIEEYFGVRYSATTIAK
                     DLKELNIYRVPIDCETWIYKAINNQTEQEMREKFRHYCEHEVLSSIINGSYIIVKTSP
                     GFAQGINYFIDQLNIEEILGTVSGNDTTLILTASNDMAEYVYAKLFK"
     gene            2489..2656
                     /locus_tag="RFE25_002527"
                     /pseudo
     CDS             2489..2656
                     /locus_tag="RFE25_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501420.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2833..4068
                     /gene="arcA"
                     /locus_tag="RFE25_002528"
     CDS             2833..4068
                     /gene="arcA"
                     /locus_tag="RFE25_002528"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDU2817560.1"
                     /translation="MTDGPIKVNSEIGALKTVLLKRPGKELENLVPDYLDGLLFDDIP
                     YLEVAQKEHDHFAQVLREEGVEVLYLEKLAAESIENPQVRSEFIDDVLAESKKTILGH
                     EEEIKTLFATLSNQELVDKIMSGVRKEEINPKCTHLVEYMDDKYPFYLDPMPNLYFTR
                     DPQASIGHGITINRMFWRARRRESIFIQYIVKHHPRFKDANIPIWLDRDCPFNIEGGD
                     ELVLSKDVLAIGVSERTSAQAIEKLARRIFENPQATFKKVVAIEIPTSRTFMHLDTVF
                     TMIDYDKFTMHSAILKAEGNMNIFIIEYDDVNKDIAIKQSSHLKDTLEDVLGIDDIQF
                     IPTGNGDVIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNDLLRQKGIKVIEISGSEL
                     VRGRGGPRCMSQPLFREDI"
     gene            4101..5111
                     /gene="argF"
                     /locus_tag="RFE25_002529"
                     /pseudo
     CDS             4101..5111
                     /gene="argF"
                     /locus_tag="RFE25_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501418.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
     gene            5202..6632
                     /gene="arcD"
                     /locus_tag="RFE25_002530"
     CDS             5202..6632
                     /gene="arcD"
                     /locus_tag="RFE25_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HDU2817561.1"
                     /translation="MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAII
                     IGWIITAIGMISLAFVFQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLG
                     NVAYATLLMSAVGNFFPIFKGGNTLPSIIVASLLLWGVHFLILKGVETAAFINSIVTV
                     AKLIPILLVIICMIIAFNFDTFKTGFFGMTSEGVLPFSWASTMSQVKSTMLVTVWVFI
                     GIEGAVIFSSRAKNKKDVGSATVIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMA
                     QVLATIVGGWGSTLVNIGLIISVLGAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNG
                     APVNALLITNILVQLFLISMLFTQSAYQFAFSLASSAILYPYMFSAFYQVKYTLEHRQ
                     QATTKQWTIGIIASIYAIWLIYAAGINYLLLTMLLYIPALLVYSIVQKNNQTRLIKSD
                     YILFMIIIVLAVIGLIKLLMGTINVF"
     gene            6649..7590
                     /gene="arcC"
                     /locus_tag="RFE25_002531"
     CDS             6649..7590
                     /gene="arcC"
                     /locus_tag="RFE25_002531"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDU2817562.1"
                     /translation="MKEKIVIALGGNAIQTKEATAEAQQTAIRRAMQNLKPLFDSPAR
                     IVISHGNGPQIGSLLIQQAKSNSDTTPAMPLDTCGAMSQGMIGYWLETEINRILTEMN
                     SDRTVGTIVTRVEVDKDDPRFNNPTKPIGPFYTKEEVEELQKEQPDSVFKEDAGRGYR
                     KVVASPLPQSILEHQLIRTLADGKNIVIACGGGGIPVIKKENTYEGVEAVIDKDFASE
                     KLATLIEADTLMILTNVENVFINFNEPNQQQIDDIDVATLKKYAAQGKFAEGSMLPKI
                     EAAIRFVESGENKKVIITNLEQAYEALIGNKGTHIHM"
     gene            7689..8393
                     /locus_tag="RFE25_002532"
     CDS             7689..8393
                     /locus_tag="RFE25_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDU2817563.1"
                     /translation="MTENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYT
                     KGQVIYFSPQESSNIYFLIEGNIIREHYNQNGDVYRYFNKEQVLFPISNLFHPKEVNE
                     LCTALTDCTVLGLPRELMAFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDR
                     IIKLLCHLCQTVGYDQDEFYEIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKD
                     HKNWLVSKHLFNDVCV"
BASE COUNT         3108 a         1180 c         1637 g         2554 t
ORIGIN      
        1 tttaaaaaag aaaagaatca ataaataaaa tcaacgaaca aaaagtatcg aaataaatag
       61 aaataatcat ttacttttct gaaaaattaa attaatattt tatttataag ctgtttttaa
      121 gatttcagga ggaatgaaat gtgaggaaat tttcaagata tgcatttaca agtatggcag
      181 cagtaacatt gttgagcact ttatcaccag cagcattagc gattgattca aaaaataaac
      241 cagctaattc tgatattaaa tttgaggtga ctcaaaagag tgatgcggtc aaagcattaa
      301 aagaattgcc taaatccgaa aatgtaaaaa atatttatca agattacgct gttactgatg
      361 taaaaactga taaaaaagga tttacgcatt atacattgca accgagtgtt gatggtgttc
      421 atgcacctga caaagaagtg aaagtacacg cagacaaatc aggaaaagtc gttttaatca
      481 atggggatac tgatgcgaag aaagtaaagc caacgaataa agtgacatta agtaaagatg
      541 acgcagccga caaagcattt aaagcagtta agattgataa gcataaagcg aaaaatctta
      601 aagataaagt cattaaagaa aacaaagttg aaatcgatgg tgacagtaat aaatacgttt
      661 ataatgttga gttaattaca gtgacaccag aaatttcaca ttggaaagtt aaaattgatg
      721 ctcaaactgg cgaaatttta gaaaaaatga acttagttaa agaagctgca gaaactggta
      781 aaggaaaagg tgtacttggc gatacaaaag atatcaatat caatagtatt gacggtggat
      841 ttagcctaga agatttaacg catcaaggta aattatcagc atttagcttt aatgatcaaa
      901 caggtcaagc aacattgatt actaatgaag atgaaaactt cgtaaaagat gagcaacgtg
      961 ctggcgtaga tgcaaattat tacgctaaac aaacatatga ttattacaaa gacacatttg
     1021 gtcgtgaatc atatgacaac caaggtagtc caattgtttc attaacgcat gttaataact
     1081 acggtggtca agataacaga aataatgccg catggattgg tgacaaaatg atctatggtg
     1141 atggtgatgg tcgcacattc acaagtttat cgggtgcaaa tgacgtagtg gcacacgaat
     1201 taacacacgg tgtgacacaa gagactgcga acttagaata taaggaccag tcaggcgctc
     1261 taaatgaaag cttttcagat gtttttggat actttgtaga tgacgaggat ttcttaatgg
     1321 gtgaagatgt ctacacacct ggaaaagagg gggacgcttt acgcagcatg tcaaacccag
     1381 aacaatttgg tcaaccagct catatgaaag actatgtatt cactgaaaaa gataatggtg
     1441 gcgtacatac gaattctgga attccaaata aagcagctta taacgtgatt caagcaatag
     1501 ggaaatctaa atcagaacaa atttactacc gagcattaac ggaatactta acaagtaatt
     1561 caaacttcaa agattgtaaa gatgcattat accaagcggc taaagattta tatgacgagc
     1621 aaacagctga acaggtgtat gaagcatgga atgaagtagg cgtggagtaa aaatatataa
     1681 acaagaagaa gtaatgttaa acacttataa ataattaaat tttaaataca gcttatatat
     1741 ggggtatacc tacattgata attgactttg taggtatacc ctctctttgt aattagatga
     1801 gaggagtgtg agggttgtct gccgaaagac tactcggcag tctaaaatca ttacaagtag
     1861 tagatatgtg ataattaaat gctgacttag aatacaaaat tcattttaaa agttgtcaca
     1921 aaaaatttac atgtattttt attatctttt gcaaaacaaa gtgttaaatt ataaatgaaa
     1981 catgcatgaa tttatttttt aatacaagaa acgtaactac caaaggagtt tacaatatga
     2041 agaaaagtaa acgattagaa attgtttcta caatagttaa aaagcataag atttataaaa
     2101 aagaacaaat catttcatat attgaagaat attttggtgt aagatatagt gcaacaacaa
     2161 ttgctaaaga cttgaaagaa cttaatatat atcgtgtccc tatcgattgt gaaacatgga
     2221 tttataaagc tattaataat caaacagaac aagagatgag agaaaagttt agacactatt
     2281 gtgaacatga agttctaagt tcaatcatca atggttcata cattatcgtt aaaacctcac
     2341 ctggtttcgc ccaaggcata aactatttta tcgatcagct aaatatagaa gagatattag
     2401 gtacggtgag tggaaatgac actacattaa tcttaactgc ctcaaatgat atggcagaat
     2461 acgtatatgc aaaattattt aaatagacat gtatcaaatg aataataaaa attagtttcg
     2521 tatcacgtgt acacaagtta gttaccaaat attaacttgt gtacgcgttt ttttatggaa
     2581 agaaagaatt catagtcatt catttgactg tataaaaaac tttatacaac gtgtttttgt
     2641 gggtcttttt gaataaaaaa tgtatatttt gacccaaaac acctttattt atgtataaaa
     2701 atccattatt atgtattgta taacaaaaag atatgaaatt ttcgactttc tttatgtgaa
     2761 tataatcaca tgtaagcgtt tgaagattgt ctatactcta aatgaattca aagataaaag
     2821 gaggaaatag acatgacaga tggtccaatt aaagtaaata gcgaaattgg agctttaaaa
     2881 actgtgttac ttaagcgtcc tggaaaagaa ttagaaaatt tagtacctga ttatttagat
     2941 ggattactat ttgatgatat tccatattta gaagtagctc aaaaagagca tgaccatttt
     3001 gcgcaggtgc taagagaaga gggtgttgaa gtactttacc ttgagaagtt agcagctgaa
     3061 agtattgaaa atcctcaagt aagaagtgaa tttattgatg atgtattagc agagtctaaa
     3121 aaaacaatat taggtcatga agaagaaatt aagacattat ttgcgacact ttctaatcaa
     3181 gaacttgtag ataaaataat gtcaggggta cgtaaggaag aaattaatcc gaaatgtaca
     3241 catctagtag agtacatgga tgataagtat ccattctatt tagatccaat gccaaacctt
     3301 tattttacta gagatccaca agcctcaata ggacacggta taacaatcaa tcggatgttc
     3361 tggagagcac gacgacgaga atcaatattt attcaatata ttgtaaagca tcatcctaga
     3421 tttaaagatg cgaatattcc aatctggtta gatcgagatt gcccattcaa tattgaaggc
     3481 ggcgatgaac ttgttttatc taaagatgtc ttggctatag gcgtttcaga acgtacatct
     3541 gcacaagcta ttgaaaagtt agcgcgacgt atttttgaaa atccgcaggc gacgtttaaa
     3601 aaagtagtag caattgaaat tccaactagt cgaactttta tgcacttaga tacagtattt
     3661 acaatgatag attatgacaa atttacaatg cattcagcca ttttaaaggc agaaggcaat
     3721 atgaatatat ttattattga atatgatgac gtaaataaag atattgccat caaacaatct
     3781 agtcatttaa aagatacttt agaagacgta ctaggtatag atgatatcca attcattcca
     3841 acaggaaatg gtgatgtcat tgatggtgct agagagcaat ggaatgatgg ctcaaataca
     3901 ttatgtataa gaccaggcgt tgtagtgact tacgatagaa actatgtatc gaatgattta
     3961 ttgagacaaa aaggcataaa agtcattgaa atatctggta gcgagctggt acgtggacgt
     4021 gggggcccta gatgtatgag tcaaccacta ttcagagaag acatttaacg taataaatta
     4081 tagaagcgag ggtgaaaata atgacagaaa ttcaaaaacc gtatgattta aaaggcagat
     4141 cattattaaa agaaagtgat tttaccaaag cagaattcga aggacttatt gattttgcaa
     4201 ttacattaaa agagtataag aaaaacggta ttaagcatca ctacttatct ggaaaaaata
     4261 ttgcactact attcgaaaag aattcgacga gaacgcgtgc agcgtttaca gttgcgtcta
     4321 ttgatttagg tgcgcatcca gaatttttag ggaaaaatga tattcaatta ggcaaaaaag
     4381 aatctgtaga ggatactgcg aaagtattag gtagaatgtt cgatggtatt gaattccgtg
     4441 gtttttcaca acaagctgtt gaagatttag cgaagttctc tggtgtaccg gtgtggaatg
     4501 gattaacaga cgattggcat cctacacaaa tgttagctga ttttatgaca ataaaagaga
     4561 attttggata tctagaagga ataaacttaa cttacgttgg agatggacgt aataatattg
     4621 cgcattcatt aatggtagca ggtgctatgt taggtgttaa tgtaagaatt tgtacaccta
     4681 aatcattaaa tccaaaagag gcatatgttg atattgcaaa agaaaaagcg agtcaatatg
     4741 gtggttcaat catgattacg gataatattg cagaagcagt tgaaaataca gatgctatat
     4801 atacagatgt ttgggtatcg atgggtgaag aaagtgaatt tgaacaacgt attaatttat
     4861 taaaagacta tcaagtgaat caatagatgt ttgatttaac aggtaaagat tcaacgatat
     4921 tcttacattg tttaccagca ttccatgata caaatacact ttatggacaa gaaatttatg
     4981 aaaaatatgg attagctgaa atggaagtta cagaccaaat ctttagaagt gaacattcaa
     5041 aagtgtttga tcaagctgaa aatagaatgc atacaattaa ggcagtaatg gcagcaacat
     5101 tggggagtta atcactaaat ggaacgatat gaatatgatg tgtctgatga tataagtgtc
     5161 atgtacagac acctcatatt ggtattaaag gagaaatgaa tatgaacgaa tcaggagata
     5221 acaaactcag taaatcttct ttaattggac tagttatagg atccatgatt ggtggcggtg
     5281 cgttcaatat aatgtctgat atgggcggta aagccggtgg attagccatt attattggtt
     5341 ggattattac agctatagga atgatttcat tagcgttcgt atttcaaaat ttaaccaatg
     5401 aacggccgga gctagacggt ggtatttata gttatgctca agcaggattt ggcgattttg
     5461 taggatttat cagtgcttgg ggatattggt tctcagcgtt tttaggcaat gttgcctatg
     5521 caacactatt gatgtcagca gtaggtaact ttttcccgat ttttaaagga ggcaacacat
     5581 taccaagtat tattgtcgcc tcgttactac tctggggtgt ccatttcttg attttaaaag
     5641 gcgttgaaac agcagcattt atcaatagta ttgttactgt tgcaaagtta atcccgattt
     5701 tacttgtaat catatgcatg ataattgcat tcaattttga cacttttaaa acaggctttt
     5761 tcggtatgac gtcagagggt gtattgccat ttagttgggc gagcacaatg agccaagtta
     5821 aaagtacgat gctagtgaca gtttgggtgt ttatcggtat cgaaggtgca gtaatttttt
     5881 ctagtagagc taaaaataaa aaagatgtag gtagtgccac ggttatagga cttatatcag
     5941 ttttaattat ctatttctta ttaactgtat tagctcaagg cgtgattttg caaaatcata
     6001 tttctcaatt agattcgcca agtatggcac aggtgcttgc aactattgta ggtggttggg
     6061 gatctacact tgtaaatatt ggtttaatta tttcggtact aggtgcatgg ttaggatgga
     6121 cattgcttgc tggtgaatta cctttcattg ttgcaaaaga tggattattt ccaaagtggt
     6181 ttgctaaaga aaataaaaat ggagcacctg taaatgcact gcttattacc aatatattag
     6241 tacaattatt tttaataagt atgctattta cacagagtgc gtatcaattt gcattttcac
     6301 tagcatcaag tgctatttta tacccttaca tgttcagtgc attttaccaa gttaaataca
     6361 ctttagagca tcgacagcaa gcaactacta aacaatggac gattggcatc atagcctcaa
     6421 tttatgctat atggcttata tatgcagcag gtatcaatta cttattattg acgatgttac
     6481 tttatattcc agctcttctt gtttattcaa tcgttcaaaa gaataatcag acacgtttga
     6541 ttaaatcaga ctatattctt tttatgatta ttatcgtact tgcagttatc ggattaatta
     6601 agttattgat gggaacgata aatgtttttt aaaaggagcg acaaaaatat gaaagagaaa
     6661 attgtcattg cattaggcgg taatgcgata cagacaaaag aagcaacagc tgaagcacaa
     6721 caaacagcta ttagacgtgc gatgcaaaac cttaaacctt tatttgattc accagcgcgt
     6781 attgtcattt cacatggtaa tggcccacaa attggaagtt tattaatcca acaagctaaa
     6841 tcgaacagtg acacaacgcc ggcaatgcca ttggatactt gtggtgcaat gtcacagggt
     6901 atgataggct attggttgga aactgaaatc aatcgcattt taactgaaat gaatagtgat
     6961 agaactgtag gcacaatcgt tacacgtgtg gaagtagata aagatgatcc acgattcaat
     7021 aacccaacca aaccaattgg tcctttttat acgaaagaag aagttgaaga attacaaaaa
     7081 gaacagccag actcagtctt taaagaagat gcaggacgtg gttatagaaa agtagttgcg
     7141 tcaccactac ctcaatctat actagaacac cagttaattc gaactttagc agacggtaaa
     7201 aatattgtca ttgcatgcgg tggtggcggt attccagtta taaaaaaaga aaatacctat
     7261 gaaggtgttg aagcggttat agataaagat tttgctagtg agaaattagc aacgctgatt
     7321 gaagcagata ccttaatgat tcttacgaat gtagaaaatg tatttattaa ctttaatgaa
     7381 cctaatcaac aacaaatcga tgatattgat gtagcaacac tgaaaaaata cgcggcacaa
     7441 ggtaagtttg cggaaggatc gatgttgcca aaaatagaag ctgcgatacg atttgttgaa
     7501 agtggggaaa acaaaaaagt tatcattacc aatttagagc aggcatacga agctttgatt
     7561 ggtaataaag gtacacacat tcacatgtag cactttatca cgcgacaaaa cattaaatat
     7621 gtttctccgt tgattcaaat gaaaaagttg tctgctgaca ctttgcaagg tttgaaggag
     7681 tttaacttat gacagaaaac tttattttgg gtagaaataa taaattagaa catgaactaa
     7741 aggcattagc agattacatt aatatcccat atagtatatt acaaccatat caaagtgaat
     7801 gttttgtcag acattatacg aaaggccaag ttatttattt ttcgccacaa gaaagtagca
     7861 atatttactt tttaattgaa ggtaatatta ttagagaaca ttacaatcaa aatggagatg
     7921 tatatcgtta ttttaataaa gagcaagtat tatttccaat cagtaactta tttcatccga
     7981 aagaggttaa cgaattgtgt acagcattaa ccgattgtac agttcttgga ttgcctagag
     8041 aattgatggc ttttttgtgc aaagctaatg atgatatatt tttgacactt tttgcattaa
     8101 taaatgataa tgagcagcaa cacatgaact ataacatggc attaacaagt aaatttgcta
     8161 aagatcgaat tattaaattg ttatgtcatc tatgtcagac agtagggtac gatcaagatg
     8221 aattttatga aatcaaacag tttttaacta ttcaactcat gagtgatatg gctgggattt
     8281 cccgggaaac agctggtcat attattcatg aacttaaaga tgaaaaactt gttgttaaag
     8341 atcataaaaa ttggttagta agcaaacatt tattcaatga tgtatgtgtt taatatacaa
     8401 tgtaaaatga ataagttgaa catgaggtct aacgtacatt tatacgttag gccttttttg
     8461 ctagcatgat gaataattt
//
LOCUS       DAPDIM010000093         8454 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000093 DAPDIM010000000
VERSION     DAPDIM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8454
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.093"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            195..986
                     /gene="pgeF"
                     /locus_tag="RFE25_002533"
     CDS             195..986
                     /gene="pgeF"
                     /locus_tag="RFE25_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDU2817564.1"
                     /translation="MNDNFKKQPHHLIYEELLQQGITLGITTRGDGLSDYPKNAFNMA
                     RYIDDRPYNITQHQLQLAEEIAFDRKNWVFPIQTHENKVACITKDDIGTNIDTLTDAL
                     HGIDAMYTYDSNVLLTMCYADCVPVYFYSTKHHFIALAHAGWRGTYTEIVKEVLKHVN
                     FDLKDLHVVIGPSTSSSYEINDDIKNKFETLPIDSANYIETRGRDRHGIDLKKANAEL
                     LNYYGVPKENIYTTAYATSEHLELFFSYRLEKGQTGRMLAFIGQQ"
     gene            1010..1678
                     /locus_tag="RFE25_002534"
     CDS             1010..1678
                     /locus_tag="RFE25_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDU2817565.1"
                     /translation="MKDNLQQISTQINDKSEKNNFSTKPNVIAVTKYVTIERAKEAYE
                     AGIRHFGENRLEGFFQKKEALPSDAVIHFIGSLQSRKVKDVINDVDYFHALDRLSLAK
                     EINKRAEHKIKCFLQVNVSGEASKHGIALEDVDQFIDDLKKYDKIEIVGLMTMAPLTD
                     DEAYIRSLFKQLRLKKEEIQRLNLEYAPCDELSMGMSNDYLIAVEEGATFVRIGTKLV
                     GEEE"
     gene            1675..2238
                     /locus_tag="RFE25_002535"
     CDS             1675..2238
                     /locus_tag="RFE25_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDU2817566.1"
                     /translation="MSHLALKDLFSGFFVIDDEEEVEVPDKQQQVNEAPAKEQSQQTT
                     KQNAIKSVPQKSASRYTTTSEERNNRMSNYSKNNSRNVVTMNNATPNNASQESSKMCL
                     FEPRVFSDTQDIADELKNRRATLVNLQRIDKVSAKRIIDFLSGTVYAIGGDIQRVGTD
                     IFLCTPDNVEVAGSITDHIENMEHSFD"
     gene            2250..2540
                     /locus_tag="RFE25_002536"
     CDS             2250..2540
                     /locus_tag="RFE25_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDU2817567.1"
                     /translation="MDINVLATIFKFILFVVEIYYFGMIIYFFTSWVPSIRETKVGYF
                     LAKIYEPFLQPFRKVIPPIGIIDISSIAAIIVLVLFQKGLLQIFNWILIQLQ"
     gene            2650..3429
                     /locus_tag="RFE25_002537"
     CDS             2650..3429
                     /locus_tag="RFE25_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDU2817568.1"
                     /translation="MINIDIYQHFRQEEYELIDQLTDKCDQAEQHYAPVLTHFLDPRG
                     QYILEVICGSYEDLNVSFYGGPNAERKRAIISPNYYEPKESDFELTLMEIEYPEKFVT
                     LKHQHILGTLMSLGIEREQVGDIIVNERIQFVLTSRLESFIMLELQRIKGASVKLYTI
                     PVTDMIQSNENWKNESATVSSLRLDVVIKEMIRKSRTIAKQLIEKKRVKVNHTIVDSA
                     DFQLQANDLISIQGFGRAHITDLGGKTKKDKTHITYRTLFK"
     gene            3453..4070
                     /locus_tag="RFE25_002538"
     CDS             3453..4070
                     /locus_tag="RFE25_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDU2817569.1"
                     /translation="MPFTPNEIKNKEFSRVKNGLEPTEVANFLEQLSTEIERLKEDKK
                     QLEKVIEERDTNIKSYQDVHQSVSDALIQAQKAGEETKQAAEKQAEAIIAKAEAQANQ
                     MVGDAVEKARRLAFQTEDMKRQSKVFRSRFRMLVEAQLDLLKNEDWDYLLNYDLDAEQ
                     VTLENIHHLHENDLKPDEVAANAQNNASNTPDNNQQSNDSETTKK"
     gene            4291..7044
                     /gene="ileS"
                     /locus_tag="RFE25_002539"
     CDS             4291..7044
                     /gene="ileS"
                     /locus_tag="RFE25_002539"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDU2817570.1"
                     /translation="MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKN
                     KGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIE
                     QALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE
                     AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDK
                     GVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALD
                     WDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDD
                     YIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITH
                     SYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGE
                     WVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGF
                     THPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSS
                     ITTSVATRGVSPYKFLLSHGFFMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSS
                     TDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLL
                     NRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRS
                     MQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKW
                     RTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVS
                     QVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVK
                     SLV"
     gene            7335..8132
                     /locus_tag="RFE25_002540"
                     /pseudo
     CDS             7335..8132
                     /locus_tag="RFE25_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499700.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(8193..8408)
                     /locus_tag="RFE25_002541"
                     /pseudo
     CDS             complement(8193..8408)
                     /locus_tag="RFE25_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3084 a         1182 c         1579 g         2609 t
ORIGIN      
        1 tactaatttt tagaacatgt agaaggacat ttaagttttt cgaagtcatt aaaagtgttt
       61 aagtatcgtg tcaaaattaa gtcaaaaatt atttgcgcaa cattttaact ttaaacataa
      121 atgttatatt atataattat taactttgta cagttagacg aagataattt aaatgaaatg
      181 atggtgacga tcgagtgaat gataatttta aaaagcaacc gcatcattta atatatgaag
      241 aattattaca acaaggtatt actctaggta ttacaactag aggagatggt ttaagcgact
      301 atcctaaaaa tgcttttaat atggcgagat atattgatga tcgcccatat aatattactc
      361 aacatcaatt gcaattagct gaagaaattg cgtttgatag aaaaaattgg gtgtttccca
      421 tccaaacaca tgaaaataaa gtcgcttgta ttacaaagga tgatataggc acaaatatag
      481 acactttaac tgatgcgctt catggtattg atgcgatgta cacatatgat agtaatgtct
      541 tattaacgat gtgttatgca gactgtgtac cagtatattt ttatagtaca aaacatcatt
      601 ttattgcatt ggcgcatgca ggttggcgtg gtacctatac tgaaattgta aaagaagtgc
      661 taaaacatgt gaactttgat ttgaaagact tacatgtcgt tattggacca tctacatcat
      721 caagttatga aattaatgat gatattaaaa ataaatttga aacattgcca attgatagtg
      781 ccaactatat tgaaactaga ggacgagatc gtcatggtat tgatttgaaa aaagccaatg
      841 ctgaattatt aaattattat ggtgttccta aagaaaatat ttatacgaca gcgtatgcta
      901 catctgaaca tttagaatta tttttctctt atcgattaga aaaaggtcaa acaggacgca
      961 tgttagcatt cattggtcaa cagtaaacaa ggaggagata tgtttgcgtg tgaaagataa
     1021 tttacaacaa atctcaacac aaattaatga caaaagtgaa aaaaataatt tttcaacaaa
     1081 accaaacgtg attgcagtta caaaatatgt tacaatagag cgagctaaag aagcgtatga
     1141 ggctggaata agacattttg gtgagaatag attggaaggc ttttttcaaa agaaagaagc
     1201 attaccatca gatgcggtga ttcattttat aggatcatta caatctcgaa aagttaagga
     1261 cgttataaac gacgtagatt atttccatgc tttagatcga ttgagcttag ccaaagaaat
     1321 taacaaacgt gcagaacata aaattaaatg tttcttgcaa gtgaacgttt cgggagaagc
     1381 ttctaaacat ggtattgctt tagaagatgt tgatcagttt atagatgatc ttaaaaaata
     1441 tgacaaaatc gaaattgtag gtttaatgac gatggcacca ttgacagatg atgaagcata
     1501 tattagatcg ttatttaaac agttacgttt gaaaaaagaa gaaatacaac gactcaattt
     1561 agaatatgcg ccttgtgatg aattatcaat gggaatgagt aatgactatc ttattgcagt
     1621 tgaagaaggt gcgacgtttg ttagaattgg gactaaactt gtaggagaag aggagtgagc
     1681 cacttggctt taaaagattt atttagtgga ttttttgtaa tagatgatga agaggaagta
     1741 gaagtacctg acaaacaaca acaggtcaat gaagcgccag caaaagagca gtcacaacaa
     1801 acaacaaaac aaaacgcaat caaatcagtc cctcaaaaat ctgcatcaag atatacaaca
     1861 acgtcagaag aaaggaataa ccgtatgtct aattattcaa aaaataattc acgtaatgtt
     1921 gtaactatga acaatgctac accaaacaat gcatcacaag aaagttcaaa aatgtgttta
     1981 ttcgaaccac gtgttttttc agatacacaa gatattgctg atgagcttaa aaaccgccgt
     2041 gcgacacttg tcaatttaca acgtattgat aaagtatcag cgaaaagaat tattgatttt
     2101 ttaagcggta ctgtttatgc aatcggtgga gatatccaac gtgtaggtac tgatattttc
     2161 ttatgtacgc ctgataatgt ggaagtagct ggaagcatta cagaccatat tgaaaatatg
     2221 gaacattcat tcgactaagg agttaacata tggatataaa tgtgctagct acaatattta
     2281 aatttatcct ttttgttgtt gaaatttatt atttcggcat gattatatat ttctttacat
     2341 cttgggtacc aagtattaga gaaactaagg taggttattt tttagcgaaa atatatgaac
     2401 ctttcttaca accatttaga aaagtaattc cacctattgg aattatcgac atatcatcaa
     2461 tcgctgcaat tatcgtttta gtattattcc aaaaagggtt actccaaatc tttaattgga
     2521 ttttaattca attacaataa attaagcgac ataacgaggc aagggtacat gatactttag
     2581 cctcgttttt gatatgtatt tttctgaata taagggcaat agatggtatt ttataatttt
     2641 tttaaggtag tgattaacat agatatttat caacacttta gacaggaaga atacgaatta
     2701 attgatcagc taacggataa atgtgatcaa gcggaacaac attatgcacc agtattaacg
     2761 cattttttag atccaagagg gcaatatata ttggaagtga tttgtggcag ttatgaagat
     2821 ttaaacgtct ctttttatgg cgggcctaat gctgaaagaa aaagagcaat catttcgccg
     2881 aactattatg aacctaaaga aagtgacttt gaattaactt taatggaaat agagtatcct
     2941 gaaaaattcg tcactttaaa acatcaacat attttaggga cattaatgtc tttaggtatc
     3001 gaacgcgaac aagttggaga tataattgtg aatgaacgaa ttcaatttgt tttgacaagt
     3061 agattggaat catttattat gttagaatta caacgtatta aaggcgcatc agttaaactt
     3121 tatactattc cagtaacaga tatgatacaa tctaatgaga attggaaaaa tgaaagtgca
     3181 acagttagtt ctttaaggtt agatgttgtt attaaagaaa tgatacgtaa atcacgtacg
     3241 attgcgaaac aactaattga aaaaaaacgt gttaaagtga atcacactat tgttgattca
     3301 gcagattttc aattacaagc aaatgattta atatccatcc aaggttttgg tagagcacac
     3361 attactgact taggtggtaa aactaaaaaa gataaaacgc acattaccta tagaacatta
     3421 ttcaaatagt aatgatttaa ggaggataac aaatgccttt tacaccaaat gaaattaaga
     3481 ataaagagtt ttcacgtgta aagaatggtt tagaacctac tgaagttgct aattttttgg
     3541 agcaactaag cactgaaatt gaacgtctta aagaagataa aaaacaactt gaaaaagtaa
     3601 tcgaagagag agatactaat attaagtctt atcaagacgt gcatcaatct gtaagtgatg
     3661 ctttgataca agctcaaaaa gctggtgaag aaactaagca agctgcagag aaacaagctg
     3721 aagcgattat agctaaggca gaagcgcaag ctaatcaaat ggttggtgac gcggtagaaa
     3781 aagcacgccg tttagcattc cagactgaag atatgaaacg tcaatcaaaa gtatttagat
     3841 cgcgtttccg tatgttagtt gaagcgcaat tagacttatt aaaaaacgaa gattgggatt
     3901 acttgttgaa ttatgattta gacgctgaac aagtgacgct tgaaaatatt catcatttgc
     3961 atgaaaatga tttaaagcca gatgaagttg cagcaaatgc acaaaataat gcatcaaata
     4021 caccagacaa taatcaacaa tccaatgatt cagaaacaac taagaagtaa gaattaaata
     4081 aagacagacg cgtaatatac atttaacttt tcacagcgaa ttaggtaatg gtgagagcct
     4141 agtaaaagca tgtatgttat atcactggct ttttaatatt taaataatgt aatgagagaa
     4201 ctctaagttg agttaataag ggtggtaccg cgagcaatcg tcccttttaa tttaacttag
     4261 agttttttaa atttttaagg agtgaaaaaa atggattaca aagaaacgtt attaatgcct
     4321 aaaacagatt tcccaatgcg aggtggttta ccaaacaagg aaccgcaaat tcaagaaaaa
     4381 tgggatgcag aagatcaata ccataaagcg ttagaaaaaa ataaaggtaa cgaaacattc
     4441 attttacatg atggcccacc atacgcgaat ggtaacttac atatgggaca tgccttgaac
     4501 aaaattttaa aagactttat tgtacgttat aaaactatgc aagggttcta tgcaccatac
     4561 gtaccaggtt gggatacaca tggtttacca attgaacaag cattaacgaa aaaaggtgtt
     4621 gaccgaaaga aaatgtcaac agctgaattc cgtgagaaat gtaaagaatt tgctttagaa
     4681 caaattgaat tacagaaaaa agattttaga cgtttaggtg ttcgtggtga ctttaatgat
     4741 ccatatatta cattaaaacc tgaatacgaa gctgcacaaa ttcgtatttt tggagaaatg
     4801 gcagataaag gtttaattta taaaggtaaa aagccagttt attggtctcc ttcaagtgag
     4861 tcttcattag cagaagcaga aattgaatat cacgataaac gttcagcatc aatttacgtt
     4921 gcatttgacg ttaaagatga caaaggtgtc gttgatgcag atgctaaatt tattatctgg
     4981 acaacaacgc catggacaat tccatcaaat gttgcgatta ccgttcatcc tgaattaaaa
     5041 tatggtcaat acaatgtaaa tggcgaaaaa tatattattg cagaagcctt gtctgacgct
     5101 gtagcagaag cactggattg ggataaagca tcaatcaaat tagaaaaaga atacacaggt
     5161 aaagaattag agtatgttgt agcacaacat ccattcttag acagagaatc gttagtgatt
     5221 aatggtgatc atgttactac agatgctggt acaggttgtg tacatacagc accaggtcac
     5281 ggggaagatg actatattgt tggtcaaaaa tatgaattgc cagtaattag tccaatcgat
     5341 gataaaggtg tatttactga agaaggcggc caatttgaag ggatgttcta tgataaagct
     5401 aataaagccg ttactgattt attaacagaa aaaggtgcac tattaaaatt agactttatt
     5461 acacatagct atccacacga ctggagaaca aaaaaacctg taatcttccg tgctacacca
     5521 caatggtttg cctcaatcag taaagtaaga caagatattt tagatgcaat cgaaaataca
     5581 aacttcaaag taaattgggg taaaacacgt atttacaata tggttcgtga ccgtggcgaa
     5641 tgggttattt ctcgtcaacg tgtgtggggt gtaccgttac cagtatttta tgctgaaaat
     5701 ggcgaaatta tcatgacgaa agaaacagtg aatcatgttg ctgatttatt tgcagaacac
     5761 ggttcaaata tttggtttga aagagaagcg aaagacttac taccagaagg atttacacat
     5821 ccaggcagcc ctaacggtac atttactaaa gaaacagaca ttatggacgt ttggtttgat
     5881 tctggttcat cacaccgtgg cgtgttggaa acaagaccgg aattaagttt cccagcggat
     5941 atgtatttag aaggtagtga ccaatatcgt ggttggttca actcttctat cacaacttca
     6001 gttgctacaa gaggagtatc accttataaa ttcttacttt ctcatggttt ttttatggac
     6061 ggtgaaggta agaaaatgag taaatcttta ggtaatgtga ttgtacctga ccaagtggtt
     6121 aaacaaaaag gtgctgatat tgcgagactt tgggtaagta gtacggacta tttagctgat
     6181 gttagaattt ctgatgaaat tttaaaacaa acatctgatg tttatcgtaa aatcagaaat
     6241 acattaagat ttatgttagg taacattaac gatttcaatc ctgacacaga tagcattcct
     6301 gaatcagagt tattagaagt ggatcgttac ttgctaaatc gtttacgtga atttactgca
     6361 agtacgatta acaactatga aaactttgac tacttaaata tttatcaaga agttcaaaac
     6421 tttatcaatg ttgagttaag taatttctat ttggattacg gtaaagatat tttatatatt
     6481 gaacaacgtg attctcatat ccgtcgtagt atgcaaacag tgttatatca aattttagtt
     6541 gatatgacga agttgttagc accaatctta gtgcatacag ctgaagaagt ttggtctcat
     6601 acaccacatg ttaaagaaga aagtgttcac ttagcagaca tgcctaaagt tgtagaagta
     6661 gatcaagctt tattggataa atggcgtaca tttatgaatt tacgtgatga tgtgaaccgt
     6721 gcattagaaa ctgctcgtaa tgaaaaagtt attggtaaat cattagaagc taaagttacg
     6781 attgctagta acgataaatt taatgcatct gaattcttaa cttcatttga tgcattacat
     6841 caattattta tcgtgtcaca agttaaagtt gtagataagt tagatgatca ggcaacagct
     6901 tatgaacatg gtgatattgt catcgaacat gcagatggtg aaaaatgtga aagatgttgg
     6961 aactattcag aggatcttgg tgctgttgat gaattgacgc atctatgtcc acgatgccaa
     7021 caagttgtaa aatcactggt ataattgaaa ttgtataaag tacttataca gatgatataa
     7081 attaaagctc tcttcataat catgttgtag tttttgttga catgatgaag agagtttttt
     7141 tgtgaataaa aaaatgacca agttactggt tatatgtgtt aaaaaatgtg taatttacta
     7201 aaataaaaat tattcaggaa tggtacaaat tctctgaagc ttataaatgc gttatagttg
     7261 ctattctcaa ttatgttcgc gataatttta agtaaaagta agcacagata ttgaatttga
     7321 taggagttaa ttgaatgtat cataacagta acgcaaactt tgtaaatggt atcactttaa
     7381 atgtgagaga taagaatgaa ttaaagccat tttatgagga cgtattagga ttaaatatta
     7441 taaatgagac attaacatcg atacaatatg aagtaggtca aaataatcat gtcattacac
     7501 ttgttgaatt acaaaatgga cgtgaacctt taatgtccga agcgggactg tttcatatcg
     7561 caattaaact acctcaaatt agtgatttag ctaatttact aattcattta agcgaatatg
     7621 atattccagt taacggaggt atacagcctg cttcgttata attatttttt gaagacccag
     7681 aaggaaacgg ttttaaattt tatgttgata aagacgaagc gcaatggacg aggcaaaatg
     7741 atttagtaaa aattgatatt agaccattaa atgtaccgag attagtgagt catgcaacaa
     7801 aattgttatg gttaggtatt ccagatgacg ctattatagg tgcattgcat attaagacaa
     7861 ttcatttatc agaggtaaaa gagtactacc tcgattattt tggattagag caatcggcat
     7921 atatggatga ttattcaata tttttagcat cgaatggcta ttatcaacat ttggccatga
     7981 atgattgggt atcagcaacg aaacgtgtag aaaattttga tacgtatgga ttagcaattg
     8041 ttgactttca ttatcctgaa acaacacatt taaatttaca aggtccggat ggtatctatt
     8101 atcgctttaa tcatatcgaa gttgaagatt agtatatact ttgaatggac gaaccatata
     8161 atgaatcgtt tttaatgatc tttttataca agttatgaag gaggctggga cattaagttc
     8221 ttaggcaatg taaaaagctg atttctatta attatttgat agaaatcagc ttttttgata
     8281 tgtattttat aatgtacagc tcgttgagct gctattttcc ttatattaag tgccattaat
     8341 acaaaaccta gctctcgttt aactttattt attcctcgaa ctgacattcg agtgaaactc
     8401 aaaatagcct actttcttaa attaacaata tctattctca tagaatttgt ccaa
//
LOCUS       DAPDIM010000094         7252 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000094 DAPDIM010000000
VERSION     DAPDIM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7252
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.094"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..77)
                     /locus_tag="RFE25_002542"
     CDS             complement(<1..77)
                     /locus_tag="RFE25_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1270 family protein"
                     /protein_id="HDU2817571.1"
                     /translation="MSNIYKSYLVAVLCFTVLAIVLMPFL"
     gene            complement(89..352)
                     /locus_tag="RFE25_002543"
     CDS             complement(89..352)
                     /locus_tag="RFE25_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2817572.1"
                     /translation="MPKIIVPPTPENTYRGEEKFVKKLYATPTQIHQLFGVCRSTVYN
                     WLKYYRKDNLGVENLYIDYSPTGTLINISKLEEYLIRKHKKWY"
     gene            complement(382..600)
                     /locus_tag="RFE25_002544"
     CDS             complement(382..600)
                     /locus_tag="RFE25_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817573.1"
                     /translation="MNKLYKTTLLITMAVVTWKVWKIEKHTRKPVISSRALSDYLNNK
                     SLTIPKDAENSTESARRLLKFAEQTISK"
     gene            complement(597..923)
                     /locus_tag="RFE25_002545"
     CDS             complement(597..923)
                     /locus_tag="RFE25_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817574.1"
                     /translation="MNIQKVMKLILKKIHEMREILKKFNKNIRHKDLIVIKVKDENSV
                     PLVIYKGGELKSKRVVKFLWVTRNGNYEGGYDINIEHYAKSEKGRPGRYEKSGFRSLF
                     FKEDSQ"
     gene            979..1611
                     /locus_tag="RFE25_002546"
     CDS             979..1611
                     /locus_tag="RFE25_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817575.1"
                     /translation="MYIDPLKNVRLSINNAINNVEISRSMAIKQSLKLKYQLDIINKN
                     NLNLFSNFKVDFHLNNLIEMNFNLRNSFSSLTFQRNLFSEDAIKSFKELYRFDDEIVL
                     QAQQTIRDFYINPTAISTLAEAINSTYPINEQGTYKRNDKFVNRIKNDFPHPFKQLIR
                     WSNGIAAGADIQIFVTNYINENDLHIQNSLIVAIVCLLSFLSTYCSHSKK"
     gene            complement(1626..1766)
                     /locus_tag="RFE25_002547"
     CDS             complement(1626..1766)
                     /locus_tag="RFE25_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817576.1"
                     /translation="MLQKFRIAKERNKLKLKLLKHASYCLERNNNPELLRAVAELLKK
                     VN"
     gene            complement(1783..2538)
                     /locus_tag="RFE25_002548"
     CDS             complement(1783..2538)
                     /locus_tag="RFE25_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HDU2817577.1"
                     /translation="MQALKTKSNIGEMFNIQEKENGEIAISGRELHQALEVSTRYDKW
                     FERMTEYGFENGIDFISQVEKVHGQKRARTYEQVNHILTLDTAKEIAMIQRSEPGKRA
                     RQYFIQVEKAWNSPEMIMQRALKIANNTINQLETKIERDKPKIVFADAVATTKTSILV
                     GELAKIIKQNGINIGQRRLFEWLRQNGFLIKRKGVDYNMPTQYSMERELFEIKETSIT
                     HSDGHTSISKTPKVTGKGQQYFVNKFLGEKQTS"
     gene            2595..3133
                     /locus_tag="RFE25_002549"
                     /pseudo
     CDS             2595..3133
                     /locus_tag="RFE25_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3157..3417)
                     /locus_tag="RFE25_002550"
     CDS             complement(3157..3417)
                     /locus_tag="RFE25_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDU2817578.1"
                     /translation="MEQITLTKEECVEQCINKDLKLLDYRVQQILEGVLSESTTYGDA
                     RNKLETLKIIAESHFKTEHASVIYKLALKKLDEKINATPIKE"
     gene            complement(3430..3672)
                     /locus_tag="RFE25_002551"
     CDS             complement(3430..3672)
                     /locus_tag="RFE25_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HDU2817579.1"
                     /translation="MIYNFDYSLLYERMAEYRYSQSSLANAIPISRTSINHKLQGKNL
                     FTQWEIKRICELLEIPPTKVGRYFFEQNVQKPVQMS"
     gene            3836..4552
                     /locus_tag="RFE25_002552"
     CDS             3836..4552
                     /locus_tag="RFE25_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2817580.1"
                     /translation="MNSFKDRLKQIMSERKISQSELSRRTGIGRNSISDYLNGKYEAK
                     QDKVFELAKALNVNEAWLMGFDISKNRKIENNDITSIYSKLTPPRQSNVLKYATNQLE
                     EQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALK
                     VNGDSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKK
                     YKDLYFYDNESVRLVGKVIL"
     gene            4564..5418
                     /locus_tag="RFE25_002553"
     CDS             4564..5418
                     /locus_tag="RFE25_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001620117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDU2817581.1"
                     /translation="MKPRKQDEKILSDQYSYFEPIISDSCDIKFDENKRRMGSIFISH
                     EEICFIRKEEDYIFKISLSEVIDYNTVVTIWKNQAFLTLNDNRKLTVYFVTNSPLTGF
                     ISILKTYMQLSKNKETIISNDCLPINDDEQTKVEIFDVVGLNYEGRRKELKKLIKKMK
                     NNDDFFFLYSDLKGNELKEELLYEDKVYEISDYEVIPGVFLQKEPDNPYDENAIKVMI
                     SNEYSEFHVGYVPREYASRLVNHMDNIVSCNAYINGGKYKTLDYLEEKIVTKESDYGL
                     RVHLEYKV"
     gene            5492..5638
                     /locus_tag="RFE25_002554"
     CDS             5492..5638
                     /locus_tag="RFE25_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817582.1"
                     /translation="MDFKEVDINIEEWEMVEIPFYTEEELTYRLNNGLPITKSELEEQ
                     ESKK"
     gene            5635..5820
                     /locus_tag="RFE25_002555"
     CDS             5635..5820
                     /locus_tag="RFE25_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817583.1"
                     /translation="MSSYKEIEHLHINTGGKELTQEQIEEAKAFIDSQEFKDMIREAK
                     ESRQRVMESKITDRTKM"
     gene            6020..6187
                     /locus_tag="RFE25_002556"
     CDS             6020..6187
                     /locus_tag="RFE25_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817584.1"
                     /translation="MKITNCKIKKETIVYEVLTSGNQPFTYELPKDLSSHNARKYLEF
                     ISQKIDGDKLN"
     gene            6327..6866
                     /locus_tag="RFE25_002557"
     CDS             6327..6866
                     /locus_tag="RFE25_002557"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDU2817585.1"
                     /translation="MEEKRYKVYQRGEIIYADFGKGVGHEFSYKHFCIVINKKDNKNN
                     GKVTVIPLTSKSKHNAFVNIHLIKPFLNTLKQSIAKHEKKIESIENIINQNPNDLKVI
                     VYARFLCDSLKNEMKQYDFVENKLKNLVDKSSYAKTQDITTISKDRILNYIKDLSVLI
                     RLPKHETDRLVNICFKKMS"
     gene            7039..>7252
                     /locus_tag="RFE25_002558"
     CDS             7039..>7252
                     /locus_tag="RFE25_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDU2817586.1"
                     /translation="MKTRCYDGKKWQYEFKYEGKRYRKKGFRTKREANSAGLDKLNEL
                     RSGFNIDNYITLEEYFENWIKTYKQPV"
BASE COUNT         2496 a         1093 c         1170 g         2493 t
ORIGIN      
        1 agaaacggca taagtacaat cgctaagact gtgaagcata atactgctac taggtagctt
       61 ttataaatgt tgctcattta atatcctcct aataccattt tttatgcttt ctgatcaaat
      121 actcttccaa tttagaaata ttaatcagag tgcctgttgg tgaataatca atgtataaat
      181 tttctacacc taaattatct ttgcggtaat atttcaacca gttgtatact gtacttctac
      241 atactccaaa caattgatgg atttgtgtag gcgttgcgta taactttttc acaaattttt
      301 cttcgcctct atatgtgttt tctggtgttg gtggtactat gatttttggc atttctatct
      361 ttcctttcgt gtataatgtt gttatttgct aatagtttgt tcggcgaact tcaaaaggcg
      421 acgagcagat tcagtagaat tttcagcatc tttcggtatg gttaaagatt tgttgtttag
      481 atagtcactc aacgccctgc tactaatcac aggttttcta gtgtgcttct caatcttcca
      541 aaccttccac gtcacaactg ccattgtgat gaggagggtt gttttataca atttgttcac
      601 tgtgaatcct ccttaaaaaa caaacttcta aatcctgatt tttcatatct accgggtctg
      661 cctttttcac tctttgcata atgctctatg tttatgtcgt aaccaccttc gtaatttccg
      721 tttctagtta cccataaaaa tttaactact cgtttgctct tcagctctcc acctttataa
      781 atgactaatg gaacgctgtt ttcatctttc actttgatga caattagatc tttgtgtctg
      841 atatttttgt tgaacttttt taaaatctcc ctcatctcat gaattttttt caatattaat
      901 ttcattactt tttgaatgtt catttgttac atctcttttc gtgtataatg ttgttatcaa
      961 cctaaggagg tgatattggt gtatattgat cctttaaaaa atgttcgttt atctattaat
     1021 aacgcaatta ataatgttga aatttctaga agcatggcaa ttaaacagtc tttaaaactt
     1081 aagtaccaat tagatataat taataaaaat aacttaaatt tattttctaa cttcaaagta
     1141 gactttcatc taaacaactt aattgaaatg aattttaatt tgcgtaattc tttttcttct
     1201 ctaacatttc aaagaaattt attttctgaa gatgcgataa aatcttttaa ggaactctat
     1261 aggtttgatg atgagatagt gcttcaagca caacagacca ttagagattt ttatatcaat
     1321 ccaactgcta tctctacttt ggctgaagcc atcaattcga cctatccaat aaatgagcaa
     1381 ggtacctata aaagaaacga taaatttgtc aatcgtatca aaaatgattt tccacatcct
     1441 ttcaaacagt taataagatg gtctaatggc attgcggcgg gtgctgacat tcaaatcttt
     1501 gtaacaaact atataaacga gaacgattta catattcaaa attcattgat agttgctata
     1561 gtttgtttat taagtttttt atcgacctat tgttcacatt ctaaaaagta ataataaggt
     1621 ctaatttagt taaccttctt taacaactct gcaactgctc gcaacagttc agggttgttg
     1681 tttctttcta aacagtaact agcatgcttt agtaatttga gttttaattt atttctttct
     1741 ttcgcaattc taaatttttg taacatttgc tgtgccctcc tgttaagatg tttgtttttc
     1801 tcctaaaaac ttattaacaa agtattgttg tcctttgcct gttacttttg gcgtcttact
     1861 aattgatgtg tgaccgtccg aatgtgtgat tgatgtttct ttaatttcga ataactcacg
     1921 ttccattgaa tactgtgtag gcatgttata atccacaccc ttgcgtttaa taaggaatcc
     1981 gttttgacgt aaccactcaa acaatctgcg ttgcccgatg tttataccgt tttgtttaat
     2041 gatctttgct aactctccaa ctaaaattga tgtcttagta gtagctactg catctgcaaa
     2101 tacaattttt ggtttatcac gttcaatctt tgtttctaat tgattgattg tgttgttagc
     2161 aatttttaaa gcacgttgca taatcatttc tgggctattc catgcttttt caacttggat
     2221 gaagtattgt cttgcacgtt tgccaggttc actacgttga atcattgcaa tctcttttgc
     2281 agtgtcgaga gtgagaatat gattaacttg ttcataagta cgcgcccttt tttgaccgtg
     2341 tactttttca acttgcgaaa taaaatctat cccgttttca aaaccatatt ccgtcattct
     2401 ttcgaaccac ttatcgtacc tagttgaaac ttctaatgct tgatgaagtt ctcgaccgct
     2461 gattgcgatt tctccatttt ctttttcttg tatgttgaac atttcgccga tgttcgattt
     2521 tgtttttaat gcttgcatat tgtttatgct cctttcgtgt ataatgttgt tatcaaccta
     2581 aggaggtgat aagtatggac ataatcgcga tttgtatcgc aatttttagt ttcttactga
     2641 ctgcacttaa atattattta gactatatga aagattctct taacatcgat gttataccta
     2701 ccagaagctt taattacttg gtcgatgaca aatcaagtta caacgatata acatttatta
     2761 atttcacaaa gtttcccatt tctgttattg acgttgaatt tgatattaaa aataaagtaa
     2821 atgaacaaaa aacgttcaaa cctatacgat ataaagataa aaactactcc attccattta
     2881 ctttaggacc ttatgaaagt gtagaatgta ctttttgctc gaagaatatc cagtgatatg
     2941 ggaatgggat gtgactatca aagtcactac caacaaagga atctatataa agcctgttat
     3001 catagaatcg cggacagaac accgagaatc agagccacaa gtgacagagt taacatcagc
     3061 aaataaggta agtgctcttt ccaaccccaa ggatggtttt ttaaagaagt ttttatatca
     3121 tttaaaacct taaacattta aaatcctccc tttccgtcac tctttaattg gagtggcgtt
     3181 gattttttcg tctaactttt tcaatgctaa tttgtaaata actgaagcat gttcggtttt
     3241 aaaatgagat tcagcaataa ttttcaatgt ttctaattta tttcttgcat caccgtatgt
     3301 ggtactttct gatagaacac cttctaaaat ttgttgaact cgataatcta aaagttttaa
     3361 gtctttattg atgcattgtt cgacacactc ttctttggtt aacgtgattt gttccatagt
     3421 gtcctcctgt tacgacattt gtacaggttt ctgtacattt tgttcaaaaa aatatctacc
     3481 tacttttgtt ggtgggattt ctaataattc acagattcgt tttatttccc attgtgtaaa
     3541 taaatttttt ccttgcaact tgtgattaat agatgtcctt gaaataggga ttgcgttcgc
     3601 taaagaactt tggctatatc tatactctgc cattctttcg tacagcaaac tataatcgaa
     3661 attgtatatc ataaactcac ctcccttctt gttcggtttt ctgtacaaat caattaaaac
     3721 acctttgttt aaataagtca acacataaaa tacatttttc tgtacaatat ttgttaaaaa
     3781 ttattgataa tcgtcattgt acgtagtatt atgttcttag gaggtgttca gaaatatgaa
     3841 cagttttaag gatagattaa agcaaattat gtctgaacgg aagatatctc aatcagagct
     3901 atcaagaagg actggtattg gtagaaactc aattagcgat tatttaaacg gaaaatatga
     3961 agcgaaacaa gacaaagtct ttgaactagc aaaggcttta aacgttaacg aagcgtggct
     4021 tatggggttt gatatttcta agaatagaaa aattgaaaat aacgacatca cttccatata
     4081 cagtaaactc acgcctccaa gacaaagcaa tgtactaaaa tatgcgacta atcaattaga
     4141 agaacaaaat aatgacagtg ataatctggt agatttcaat tcttacattc aagaaaaatc
     4201 cgaagtggat atatatggtt gtgcgtcagc tggtattggc gaaagattat ataacgagcc
     4261 tatttcaaaa gaattcgtaa gaggttatgt ccccgcacat gatatagctt taaaagtaaa
     4321 tggagactca atggagccgt tatttaaaaa cggacaaatt atattcattg aaaaatctca
     4381 cactatcaaa gatggacaaa taggcgtctt tattataaat ggagatgctt acgtaaagaa
     4441 agtttatgta gaagataata gattaacgtt ggtttcttta aataaaaagt ataaagattt
     4501 atatttttat gataacgaaa gtgtgaggtt agttggaaaa gttattttat aggaggtagt
     4561 aaaatgaaac ctagaaagca agatgaaaaa atattatcag atcaatacag ttactttgaa
     4621 ccaataatca gcgacagttg cgacataaaa ttcgacgaaa acaagaggag aatgggttct
     4681 atattcattt cacatgaaga gatttgtttt ataaggaaag aagaagatta tatattcaaa
     4741 atctcattat cagaggtgat agattataac actgttgtta ctatttggaa aaaccaagct
     4801 tttttaacat taaacgataa tagaaaatta acagtttatt tcgtaacaaa ctctccttta
     4861 acaggattca tctcaatttt aaaaacttat atgcaattat ctaagaataa ggaaacaatt
     4921 atctcgaatg attgtctacc tattaatgat gatgaacaaa ctaaagttga aattttcgac
     4981 gtcgtaggat taaattatga aggtcgtaga aaagaattaa agaaacttat caagaaaatg
     5041 aaaaataacg acgatttctt tttcttatat agtgatttga aaggaaatga acttaaagaa
     5101 gaattacttt atgaagacaa ggtgtatgaa atttctgatt acgaggttat tcctggtgta
     5161 ttcttacaaa aagaaccgga taatccttat gatgaaaacg cgataaaagt tatgatttca
     5221 aatgaatact ctgaatttca cgttggatat gtacctagag agtatgcttc aagattagtc
     5281 aatcatatgg acaacatcgt ttcttgtaac gcatatatta atggtggtaa gtataaaact
     5341 ttagattatt tagaagagaa aattgttact aaagaatcag actatggatt acgagtacat
     5401 ttagaataca aagtttgaga taggtaaaga ttgtattttt ataagtaatt actataaata
     5461 atagaaaatt catttcacag gagggtttaa catggatttt aaagaagttg acattaacat
     5521 tgaagagtgg gaaatggttg aaatcccctt ttatacagaa gaagaactga cttataggtt
     5581 gaataatggt ttacctataa ctaaaagtga acttgaagaa caggagtcga aaaaatgagt
     5641 tcttataaag aaattgaaca cttacacatc aatactggtg gtaaagagct tactcaagaa
     5701 caaatagaag aagccaaagc ttttatagac agtcaagaat ttaaagatat gattcgagaa
     5761 gctaaagagt cacgtcaaag agttatggag tctaaaatta ctgatagaac taaaatgtga
     5821 ttaataacgt atatttagcg ctttaatata aatataaaca aaggagaaat tgacatgaaa
     5881 aaagcaatct taactttaag tcttatattt attacctact acctcacttt taaatatatg
     5941 tggattaaag aattgaagta ttaattatgc ttatttaaaa aagacgtcta tttcagcagt
     6001 gtttgaaagg aagtttataa tgaaaataac taattgcaaa ataaaaaaag aaactatagt
     6061 atatgaagtt ttaactagtg gtaatcaacc attcacttat gagttaccta aagatttatc
     6121 gtcacataat gcgcgtaaat acttggaatt tatttcacaa aaaatagatg gcgataagtt
     6181 aaattaattc aaagaataaa gtaacttcat aaagagtacg aagaaaacga tctaatgacc
     6241 gaacttattc ttgaatattt agtaaaaaag tatgttgaag aagaatatag gaaataaacg
     6301 cctatatggc gtgaggagga tgagggatgg aagagaaacg atataaagtt tatcaaagag
     6361 gcgaaataat ttatgcagat tttggtaaag gtgtaggtca tgagttttca tacaaacact
     6421 tttgcatagt cataaacaaa aaggataata aaaataacgg caaagtgacc gtaatccctt
     6481 taacttccaa aagcaaacac aatgcttttg taaatataca tcttataaaa ccttttttaa
     6541 atacactaaa acaatcaatt gccaaacacg agaaaaagat agaatcgatt gaaaacatta
     6601 taaatcaaaa tcccaatgat ttaaaagtca ttgtttatgc aaggtttttg tgtgactcct
     6661 taaagaacga aatgaaacaa tacgattttg tggaaaacaa attaaaaaac ttagttgaca
     6721 aaagttctta tgcaaaaaca caggatatta ctacaataag taaggataga attttaaatt
     6781 atattaaaga tttaagcgtt ttaattagat tgccgaaaca cgaaactgac cgattggtta
     6841 acatctgttt caaaaaaatg agttgaacaa ttctaaaata atgttataat acaggtattg
     6901 agggctaaag gtccacctat attgatttga gctttcggct cactgacgtc tgtattatac
     6961 aggcgtcttt ttttatacaa ttttcacggg tagcccgcct acccttatta ttttttgcca
     7021 attttgagga gggaacgcat gaaaacacgt tgttacgatg gtaaaaaatg gcaatatgaa
     7081 tttaagtatg aaggaaaaag ataccgtaag aaaggtttta gaacaaagcg tgaagctaat
     7141 tctgctggac tagacaagtt aaatgagtta agaagtggtt ttaatataga taactatata
     7201 actcttgaag aatacttcga aaattggatt aaaacgtata aacaacctgt tg
//
LOCUS       DAPDIM010000095         7122 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000095 DAPDIM010000000
VERSION     DAPDIM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7122
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.095"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            458..1519
                     /locus_tag="RFE25_002559"
     CDS             458..1519
                     /locus_tag="RFE25_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDU2817587.1"
                     /translation="MSNANNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSG
                     NEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSF
                     MLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRK
                     ITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLG
                     IVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAY
                     VLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELC
                     KKFIPIYSNDIYKFEVPKQ"
     gene            1777..3234
                     /locus_tag="RFE25_002560"
     CDS             1777..3234
                     /locus_tag="RFE25_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500488.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDU2817588.1"
                     /translation="MKCLIRFILVLGLLISSAMVYINPTAHAEQDQTWEKIKERGELR
                     VGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTG
                     KIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKG
                     TEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISN
                     VKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISK
                     YGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPML
                     VQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSL
                     GLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISF
                     DPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD"
     gene            3227..3949
                     /locus_tag="RFE25_002561"
     CDS             3227..3949
                     /locus_tag="RFE25_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDU2817589.1"
                     /translation="MIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLL
                     RCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAP
                     KLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILF
                     DEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESG
                     TPVEIFEQPQHERTQNFLARVL"
     gene            4100..5227
                     /gene="queG"
                     /locus_tag="RFE25_002562"
     CDS             4100..5227
                     /gene="queG"
                     /locus_tag="RFE25_002562"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDU2817590.1"
                     /translation="MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANG
                     YASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWG
                     QDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVIN
                     PKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFL
                     TQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLR
                     MSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRAT
                     AYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE"
     gene            5232..5702
                     /gene="trmL"
                     /locus_tag="RFE25_002563"
     CDS             5232..5702
                     /gene="trmL"
                     /locus_tag="RFE25_002563"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDU2817591.1"
                     /translation="MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKM
                     LKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKAYSDFDFSNHDKDFYFIF
                     GKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN"
     gene            5861..6460
                     /locus_tag="RFE25_002564"
     CDS             5861..6460
                     /locus_tag="RFE25_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate isomerase"
                     /protein_id="HDU2817592.1"
                     /translation="MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAP
                     VLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKI
                     KTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGK
                     TSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA"
     gene            6485..6637
                     /locus_tag="RFE25_002565"
     CDS             6485..6637
                     /locus_tag="RFE25_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817593.1"
                     /translation="MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKN
                     SEEDSQ"
BASE COUNT         2535 a          919 c         1319 g         2349 t
ORIGIN      
        1 tggactcaaa tggcacacgc tttaatagac tctatgtcaa attgtaatga tgagttcaat
       61 attggaagtt aagcaactat gcattgttta acttcttttt ttggtattac attaatgata
      121 atgattatat tatctggggt tatatatttg tttcaacttt tctaataata tatttgtaaa
      181 agtgctattt tattgtgctt tataccaagt cgattcaatt tatctatctt aatagtaata
      241 tggctatttt aatatttaca atttattaca ttattagtca caggatgtaa ttagtagtat
      301 tttaagatta gcatgacatt gattagtgag tagattgttt aaatttactt tattcatttt
      361 gtggattgtt atatttagat taaattagcc aactaatcat tgttaaagtt aattttctat
      421 aatatgatga gtttaatgtt caaattggag gtcgtttatg agtaacgcaa ataatgctga
      481 taataaacag tttttcagta agattttaaa ttctattggt gctggtgttg ttattgcact
      541 tgttccgaat gctttattag gtgaagtatt aaaaatattt aaaagtggta atgaaatttt
      601 agaattaacg tatcagttag tgatactaat tcaatcattt atggcattta ttattggtgt
      661 tttagctgct catcaattta aatttaatgg cgcaggtgct gctatagtag gtacatcagc
      721 tatgattggt tcaggtgctg ttgtatatag caataatagt tttatgttaa aaggtatagg
      781 tgacattata aatacgagtt tggttgttat tattgcatgt cttatatata tggtattaca
      841 aaacaaactt ggatcttttg aattaattat attaccagtt ttagtaccta tcgttagtgg
      901 gggtatcggt ctaatcacat taccttacat tcgaaaaatt actcaagcaa ttggaaatgt
      961 aattcattct tttacagact taaatccgtt gttaatgtct atacttatta gtgtggcatt
     1021 ttcattatta atggtaacac caatatcgtt agtagcgatt gcaactgcga ttagtttaaa
     1081 cggactagga agtggagcag caaacctagg tatagtggct gcctgtgtta ctttcttatt
     1141 tggctcattg cgtgtcaatt ctattggtgt aaatgcagtt ttactcatag gagctgcaaa
     1201 aatgatgatc ccagtttact tgaaaaattt aattatttcg ataccattga ctataaatgg
     1261 aataattact ggaatcattg cttacgttct tcaggttaaa ggaacaccat tgtctgctgg
     1321 atttggatat acaggattag ttggcccaat aaatgcattt aaccgaatgt caggtgatcc
     1381 aacaatgaat attattttat tagcacttgg ttattttgtc ataccatttg tatcggcatt
     1441 tattgttcat gaattgtgta aaaaattcat tcctatatat tctaatgata tttataaatt
     1501 tgaagttcca aaacaataat tgatagcttg atgacaagaa taagttttaa tatatgataa
     1561 atataggcgt tactgtcaat aagatattga tagtagcgct tttttgattg attttaaaat
     1621 gtgagatttg ttcacgtata atagcggatt ttttatgtac agtcttttaa aaagaagctt
     1681 ttctttatat tgataaaaat acatttataa aacactattg catcaaaatg tattaatatg
     1741 tataattatg aatattaatt agggagggct gtataaatga agtgtttaat taggtttata
     1801 ttagtattag ggttgttaat tagcagtgct atggtgtata tcaatcccac agcacatgct
     1861 gaacaagatc aaacatggga gaagattaaa gaacgcggtg aacttagagt gggtctttct
     1921 gcagattatg caccaatgga atttgagcat acagttaatg gtaagactga gtatgcaggt
     1981 gtagatattg atttagctaa aaaaattgcg aaagataata atttaaaatt aaaaatcgtc
     2041 aatatgtcat ttgatagttt gttaggagct cttaaaactg gaaaaattga tattattatt
     2101 tccggaatga cttcaacgcc tgaacgtaag aagcaagttg atttttcaga ttcatatatg
     2161 atgactaaaa atatcatgct tgtaaagaaa gataaagtta atgaatataa agatatcaaa
     2221 gactttaata ataaaaaagt aggggcacaa aagggaactg aacaagaaaa aatcgctcaa
     2281 accgaaattg aaaatgcatc tattacttca ttaagccgtt taccagacgt tatattagca
     2341 ttgaaaagtg gaaaggttga aggtgctgta gttgaaaaac ctgtagcaga agcatattta
     2401 aaacaaaatc ctaaattagg aatttccaat gtgaaattta atgaagaaga aaaagataca
     2461 gtgatagctg tgccaaaaga ttcaccaaaa ttattgtcac aaattaataa aacgattaaa
     2521 gaggttaaag ataaaggatt aatcgataaa tatatgacta atgctgcaaa tgcgatgaat
     2581 gatgacagtg gttttatttc taagtatggt agttttttct tgaaaggaat taagattaca
     2641 atattaattt cacttatcgg tgttgcatta ggttctattt taggtgcatt cgttgcgtta
     2701 atgaaattaa gtaaaataaa aattatttca tggattgctt ctatctatat cgaaatatta
     2761 agaggaacac caatgttagt tcaagtattt atcgtattct ttggtataac tgctgcatta
     2821 ggactagaca tttcagctct tgtttgtgga acaattgcat tagttattaa ttcctcagct
     2881 tacattgctg aaattattcg tgcaggtata aatgctgttg ataaaggaca aatggaagcc
     2941 gcacgtagtc taggtttgaa ttatagacaa acgatgaaaa gtgtaattat gccacaagca
     3001 attaaaaata ttttaccagc tttaggtaat gaatttgtca ctttaattaa agaatcatct
     3061 attgtgtcaa caattggagt tggcgaaatt atgtttaatg cacaagtggt tcaaggtatt
     3121 tcatttgacc cattcacacc attactagtg gcagcagcat tatactttgt cttaacattt
     3181 gtacttacac gcattatgaa catgattgaa gggagattga atgccagtga ttaaaataaa
     3241 caatcttaat aaagtttttg gagataatga agttttaaaa gatatcaatc ttgaaatcaa
     3301 tcaaggggaa gtagtagcaa taataggtcc atctggtagt ggtaaaagta cattgttaag
     3361 atgtatgaat ttattagaag tacccactaa aggtcaagtg atttttgaag gcaatgactt
     3421 aacggaaaaa gggacacaag tagataaact acgtcaaaaa atgggtatgg tatttcaaaa
     3481 cttcaaccta tttccacata aaaaagttgt cgataatatt attttagctc ctaaattatt
     3541 aaagaaagat aataacgatg aattacataa ggaagcattg tcgttattag ataaagtggg
     3601 attaaaagaa aaagcagatg tatatccgaa tcaattatca ggtggtcaaa agcaaagggt
     3661 tgcaattgca agagctttag caatgcatcc agatgttatt ttattcgatg aaccaacttc
     3721 agcattagat cctgaggtag ttggtgatgt attaaaagta atgaaagacc tagccaaaga
     3781 aggtatgacc atggtggttg tgacacatga aatgggattt gccaaagatg taagtgacaa
     3841 agtcatattt atggcagatg gcgttgtcgt agagtcaggc acaccagtcg aaatatttga
     3901 acaaccgcaa catgaaagaa cacaaaattt cttagcaaga gtattataac aacctaacga
     3961 agcttgaata tatgatgcgc accacaaagt tatatcatat attcaagctt tttattatta
     4021 aaattatgtg aaatgaaacc tcaatatgaa taatggttgt gttaaaataa catagtatta
     4081 ttttatgggg ggcatacgat tggatacaaa gcagttaaag caagatatca ttgactatgc
     4141 atatacaatt ggtatcgaca gtattggatt tacaactgcc gatccctttg atgaattgaa
     4201 gcaaaagcta gaagcatatc atgcaaatgg ttatgcctca ggatttgaag aatctgatat
     4261 tgctttacga acggagccta aattatcctt accaacagca aggtcaatca tagcaattgc
     4321 agttggttat cctaacaaac tgaaaggtgc acctaagagt gttagaggtg atcgcagagg
     4381 cttatttgct agagcatcgt ggggtcaaga ttatcataca attatgcgta aacgattaga
     4441 catgttagct gcatttattg aatctaaagt tccagatgtt gaaatcaaat ctatggtaga
     4501 tacgggtgta ttatcagata gggcagtagc agaacgtgca ggtttaggat ttgttggtcg
     4561 taatggcttt gtcatcaatc ctaaactagg aacatggaca tacctcggtg aaatgttagt
     4621 cagtatacct tttgaacctg atgatccatt attagatagc tgtggtgatt gtacaatttg
     4681 tgttgatcgt tgtccaacaa gtgcattagt tggaaatggc caattaaata gtcagaaatg
     4741 cattagtttt ttaacgcaaa caaaaggcta tatgcctgac caatatcgtt ataaaattgg
     4801 gaatagatta tatggttgcg atacgtgtca acaagtttgt ccgaaaaata gaggtattaa
     4861 taccgaacaa gatgacatca ttttggaacc agaaatttta aagccaagat tagtaccttt
     4921 actacgtatg tctaataaag aattcaaaca aacatatggt caccttgcag gtgcttggcg
     4981 tggtaaaaag ccgatacaac gaaatgctat tttagcatta gcgcatttta atgaagtgga
     5041 tgcaattcca gaattgaaaa aagttgcaac aacagatgaa agaccgatga ttcgagcaac
     5101 tgcttattgg gccattggtc aaattcttgg ggaagaagca agagatttta tcaatgctaa
     5161 ttatgatcaa gaggatgcag aagttcagaa tgaaatgata aaaggattag acacaaggag
     5221 agaatagtaa tatgacaaat catatcgttt tatatcaacc agaaatccca gctaatactg
     5281 gtaacattgc acgtacgtgt gcaggtacaa acacacattt acatttaatt aaacctcttg
     5341 gatttagaac tgatgataaa atgttaaaaa gagccggttt agattattgg gaatttgtga
     5401 atattacgta tcatgatagt attgaagcat tttttgaagc cacaaatggc gagtattact
     5461 tattaacaaa atttggtaaa aaggcttata gtgattttga tttttcaaat catgacaaag
     5521 atttttactt catttttgga aaagagacga caggattacc agactgggtg aaagagaaat
     5581 atcaagacac agcgttaaga attcctatga gtgaacatat tcgttcatta aatttatcaa
     5641 atactgctgc gttgttaatt tatgaagcgt tacgtcaaca agattttcca ggattgaatt
     5701 aaaattcgtc tattttcatt ataaaaatga tacttaagtg ctatatttag agtataacca
     5761 tgttaaagtt aaatggtttg atatattgaa agttagggta taataattat taatatcgcc
     5821 gtttttatgt aaaatgcaaa ctaagaggag tgtagaaatc atggcaatga actttaaagt
     5881 ctttgacaat agtcaacttg tagcagaata tgctgctgat attattagaa agcaatttaa
     5941 caataatcct actacaattg caggttttca tttagataca gatcaagcgc cagttctaga
     6001 tgaattaaag aaaaatgttg aaaaacatgc tgttgatttt agccaaataa atattttaga
     6061 ttatgacgat aaaaaatcat atttcgaagc gttaggtgta ccagcaggtc aagtttatcc
     6121 aattgcttat gaaaaagatg caatcgaatt aatcgctgat aagattaaaa ctaaagaaaa
     6181 taaagggaaa ttaacattac aagttgtttc tatcgatgag caaggtaagt taaatgttag
     6241 tattcgtcaa ggactaatgg aagcaagaga aattttctta gtagtgacag gtgctaataa
     6301 acgagatgta gttgaaaaat tatatcaaga aaatggtaaa acaagcttcg aaccagccga
     6361 tttaaaagca catagaatgg taaatgttat tcttgataaa gaagcggctg caggtttacc
     6421 tgaagatgtt aaagcttact ttacgtcacg ctttgcttaa ttaaaaatct gtgaggtatt
     6481 gattatgtct aaagacaaag atccaaaatt aaattatcat gaagaagaaa acagtatggt
     6541 aacggatttt gaagatttaa aagaattagg taaagaaatg gaacaaatct ctgatcaaaa
     6601 tgatcaagaa aaaaattctg aagaagacag tcagtaaagt attataattg tgtaatattc
     6661 agttatttat catgtaaata atgtatagta tagaacatat atcaaatagg attgattatc
     6721 ttgaatatga agttaggtag cattttgtta cctagctttt ttattatatt catagaagct
     6781 gactttctgc cagcttctga gtttgtggcc cgtttcccca acttgcactg tttgtagaaa
     6841 ttagaaatcc gatttcacta tgttggggcc tcgccaactt gcatgaaata gtaagctgac
     6901 tttccaccag cttctatgtt tgtggactgc agttaactac tgccaatata actttgtaaa
     6961 gcataaaaca ttgatttgtg taccagacat agtaatatat caaaagttca attttaaata
     7021 ttaaaacacc atttaaacgg aattgataat taattactcc agacataatt gaaagaagtc
     7081 atctatcagt aatattttta atgaaatcat taaaccgcgt tt
//
LOCUS       DAPDIM010000096         7005 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000096 DAPDIM010000000
VERSION     DAPDIM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7005
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.096"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            13..1125
                     /locus_tag="RFE25_002566"
     CDS             13..1125
                     /locus_tag="RFE25_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001253191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDU2817594.1"
                     /translation="MRRKRKWLIVICVLLVLITISQILKHFNYGTESKEAYNTYTVEK
                     ERQLDLQGKAYPREVKTYYKNNQVGTYLGVQVADGQTVKKGDMLINYKINSNKRQQLV
                     DKINDTQHIITEVYLNITKGLNNREIQKKLIEYKQTLYEAQQQLYQYDSQNRDSMYAS
                     FDGKIMIKNIDNDSDNQPILYLISKESHIKTSVTEFDLNKVKKGDKVNLSITSTGKTG
                     AGIIKQISELPISYEENLSLHENDALHLPESNNDGELANSKSISASPIFKSNNNSELS
                     KYGVIIDDLSLPIRAGYSLEIKVPLNAIKIPKSVLTKGNNVFIVNKNSIVEKRNIRIK
                     RINGDIIVEKGLKPGDKLIKQPKSTMNDGDKVEISS"
     gene            1122..1802
                     /locus_tag="RFE25_002567"
     CDS             1122..1802
                     /locus_tag="RFE25_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817595.1"
                     /translation="MIELKNVYRTFKNGDKNIRVLKDINIHINAGEFIAIMGPSGSGK
                     STLINILGFIDREYHGEYLFEGSNYQTQSDNQLANIRNKTVGFVFQNFKLIHNNTILE
                     NISMPLVYTNMNTIERKNKVMTVLSAVGLDGKGDFTPSKLSGGQQQRVAIARAIINNP
                     KFIIADEPTGALDSDTSKIIMDIFTSLNRDNHTTIILVTHDRKVAEKADRIIHILDGR
                     IQHEEVIK"
     gene            1799..2977
                     /locus_tag="RFE25_002568"
     CDS             1799..2977
                     /locus_tag="RFE25_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817596.1"
                     /translation="MRKVLNIFTIAFKSILKNKGRNIFTMIGIIIGISSVITIMSLGN
                     GFKKTAADQFSDAGAGKQEALISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKE
                     NKEEGIEATITNVQKKSDIFIIKKQNLHSFKVGRGFDKEDNELRKKIVVINDQVAKTV
                     FNNNAIGKSLYIEGQGFEVIGITDKLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIII
                     EDGYNKKTVVKKVESLLNKKGSGSVLGEYTYTDTEEIIKSIDKIFDSITYFVAAVAGI
                     SLFIAGIGVMNVMYISVAERTEEIAIRRAFGAKSRDIELQFLIESILICVTSGFIGLI
                     LGVVFATIIDVLTPDYIKSVVSLSSVIIAVSVSILIGLLFGWIPARAASKKELIDIIK
                     "
     gene            3184..3405
                     /locus_tag="RFE25_002569"
     CDS             3184..3405
                     /locus_tag="RFE25_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cyclic bacteriocin"
                     /protein_id="HDU2817597.1"
                     /translation="MLKLHKKIAWTGIKGSAITTFITALYNGSSVWNALAVAGIAFGG
                     GAGTAVAALGRATVMRFIKRWGVRKTAAW"
     gene            3443..5161
                     /locus_tag="RFE25_002570"
     CDS             3443..5161
                     /locus_tag="RFE25_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001624188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817598.1"
                     /translation="MGKPLFKKGDSMNNSIFYTYLKFNLRYFIRRKFEIVKRSRLNVT
                     TKILFLIKLIFSSLLLFISTIMLADYFSDYIDFIEYYFYASMFIYIVFIPLIPRTKLL
                     INPMDKQLLYRSSLREVDIFNLIYASDVLKKFVGYFNLLIVGMAISLYHISPFIFNLK
                     VFCALIYFSTISYVIQIIFINIKVISTKKLFSYHYCVFNFMMGSIVSVIGFVVSFLLV
                     NLLIKPFLVFSTYVIKSKKTFEWYSYFQDIKNEVIIINEKVMQLLDYISPHTIFMRLN
                     FVNISFVIITIALFIALYYFNKIGFWYRKEDIYLSSTNINFSLPISIKAITTIQLKHW
                     ISNKEEVNLHKPFFYISYSIWFFLGCLIYFSQMAYNQLANAVIFILILNTITRDSFSA
                     GTDFFTKSLRFDSDRKSIGLYRMSNTDFKQIYDSKLSLIRFIGFKETILAIILLAIFL
                     NQDIYLYIIGFEIIIINTVIIPNLSLLPSYLSPHFNHQHYSELESFEEQIFLEDTVFD
                     KVKNFLSSSYFLILFVGYLSQRNYIDIMIFIIIFNILALILVSLFIRFSKQKITKSWR
                     KRDLYL"
     gene            5199..5663
                     /locus_tag="RFE25_002571"
     CDS             5199..5663
                     /locus_tag="RFE25_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDU2817599.1"
                     /translation="MLIIGGLLGCLVYYLLNIDLGKMIVAQDLNLQEIFFHNLIYFFS
                     AIFGFLTLGLLNIGMLLINSGMLGFFIAHGIYSNQLKSILLVLAPHAIFEILALLIAS
                     TFSLGFLSYLYQRMVKKNKIKNKMFHNFVTTIITVIVLTIIASLLEVYVTIN"
     gene            5675..6397
                     /locus_tag="RFE25_002572"
     CDS             5675..6397
                     /locus_tag="RFE25_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020808033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817600.1"
                     /translation="MLVLNNLQKKFTNSKMVLNNVNAKFRSGSINCIVGVNGAGKTTL
                     LNIISSILMPTKGDVYLNSESIFENSTLKKEIFYTPVNPFFYENLSAKDNLYLICSLY
                     NRKIDQITIEKTIKDVGLNIEDLNIPVYNFSSGMKQKLNFASMLLVDSNVLLLDEPFN
                     ALDHVAQKNFTRILKGLVSKEKIIIFTSHLPNTILELSENIYLLKDGCFTDKRKAQSF
                     NQTTLETWLLESQKEVIPYEEK"
     gene            6563..6760
                     /locus_tag="RFE25_002573"
     CDS             6563..6760
                     /locus_tag="RFE25_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817601.1"
                     /translation="MKNNLKIARVSLSMTQKELANKVGVTRQTISLIEKGVHNPSLSL
                     CKNICSVLNKNLDEIFGEKPQ"
BASE COUNT         2636 a          800 c         1141 g         2428 t
ORIGIN      
        1 ggaggacata aattgaggcg taaaaggaaa tggctaattg ttatttgtgt attattagta
       61 ttgattacga tatcacaaat tttgaaacat tttaactatg gaactgagag taaagaagca
      121 tacaatacat atacggttga aaaagaaaga caattagatt tacaaggtaa ggcatatcca
      181 cgtgaagtta aaacatatta taaaaataat caggttggaa catatttggg tgtgcaagta
      241 gcggacgggc aaacagtcaa aaaaggagac atgttaatta attataaaat aaatagtaat
      301 aaacgacagc aacttgttga taagataaat gatactcaac atattattac agaagtttat
      361 ttaaacatta ctaaaggttt aaacaatcga gagatacaga agaagttaat tgaatataag
      421 cagacattat atgaagctca acagcaattg tatcagtatg atagtcaaaa tagggatagt
      481 atgtatgcat catttgatgg caagattatg atcaagaata tagataatga cagtgataat
      541 caacctatac tgtatctcat ttcaaaggag tctcatatta aaacgtctgt tacggagttt
      601 gatttaaaca aagtcaaaaa aggagacaaa gttaacttaa gtattacgag tacgggtaaa
      661 acaggagcgg ggattataaa acaaatctct gagttgccta ttagttatga agagaattta
      721 agtcttcacg aaaatgatgc cctgcattta ccagaaagta acaacgatgg ggaattagca
      781 aattcaaaat cgatttcggc atctccaata tttaagagta ataacaactc tgaattatca
      841 aagtatggag ttataattga tgatcttagt ctaccaatac gtgcaggtta ttcgttggaa
      901 attaaagtcc cattaaatgc gattaaaata cctaaatcag tattaacaaa aggcaataat
      961 gtttttattg ttaataaaaa tagtattgtg gaaaaacgga atattcgtat aaaaagaatc
     1021 aatggtgaca ttattgtaga aaaggggtta aaacctggag acaagttaat taaacaacct
     1081 aaaagtacaa tgaatgatgg tgataaggtt gagatttcgt catgatagaa ttaaagaatg
     1141 tttataggac ttttaaaaac ggtgataaaa atattcgagt tttaaaagac attaatatac
     1201 atatcaatgc aggtgaattc atagcgatta tgggaccatc aggctcaggg aagagcacac
     1261 tgattaatat cttaggattt atagatcgag agtatcatgg tgaatatttg tttgaaggaa
     1321 gtaattatca gacacaatct gataatcaat tggcaaacat aagaaataaa acagttggat
     1381 ttgtttttca aaattttaaa ctaattcata ataatactat tttagaaaat ataagtatgc
     1441 cactggtata tacaaatatg aatacgatag aacgaaagaa taaagttatg actgtgctca
     1501 gtgctgtagg cctagatggc aaaggtgatt ttactcctag taaactatca ggcggtcaac
     1561 aacaacgtgt tgcaattgcg cgagccatta taaataatcc aaagtttatt attgcagatg
     1621 agccaacggg tgctttggat tcagatacat ctaaaattat tatggacata tttacatcat
     1681 taaaccgaga taatcatact acaattattt tagtcacaca tgatcgtaaa gtagcagaaa
     1741 aagctgatcg aataattcat attttggatg gtcgtataca acatgaagag gtgattaaat
     1801 gaggaaagtt ttaaatattt ttacaatagc ttttaaatca atattgaaaa ataaaggtag
     1861 aaatatattt acaatgatag gtataatcat cggtatttct tctgttatta cgataatgtc
     1921 tttgggaaat ggctttaaaa aaactgctgc tgatcaattt tcagatgctg gcgccggaaa
     1981 acaagaagcg ttgattagct ttacttttaa agttgatgag aaaatcaaaa agtatccttt
     2041 taatcaaaga gatatagagt tggtaaatca agttgatggc gtactagatg cgaagctaaa
     2101 ggaaaataaa gaagaaggaa ttgaagccac aataactaat gtccagaaaa aaagtgacat
     2161 cttcattata aaaaaacaaa atttacactc ttttaaagta ggtagagggt ttgataaaga
     2221 ggataatgaa ttacgtaaga aaatagtggt tataaatgat caagtagcaa aaactgtatt
     2281 caataataat gctattggta aatcgctata tattgaggga cagggatttg aagtcatagg
     2341 aattacggat aaactatatt ctgactcatc taccgttata atgcctgaaa atacattcaa
     2401 ctactatatg ggacacttac atcaaggtct gcctacctta cagataatta ttgaagatgg
     2461 ttacaataaa aaaactgtag ttaaaaaagt agaatcacta ttaaataaaa aaggatcggg
     2521 ctctgtttta ggtgagtata catatacaga cactgaagaa attatcaaaa gtattgataa
     2581 aatttttgat agtattactt attttgtagc agctgttgcc ggtatttcac tttttattgc
     2641 tggtattgga gttatgaatg tcatgtatat atctgtagct gaaagaacag aagaaattgc
     2701 gatacgacgt gcatttggtg caaaaagtcg agatattgaa ctacaatttt taatagagag
     2761 cattttaata tgtgtgacaa gtggttttat tggacttatt ttaggtgttg tgtttgcaac
     2821 aataattgat gtattaacac cagattatat taaaagtgta gtaagtttga gttctgtcat
     2881 aattgcggtt agtgtgtcga tattaattgg acttcttttt ggatggatac cagctcgcgc
     2941 agcatctaag aaagagctca tagatattat aaaatagtaa atttaaaatg gtaaaagtac
     3001 tgaagactaa ttatcatatt aaactgacta tcaacaccaa cgatggaaat gcgtattaga
     3061 ataaaagtaa gatatgtatt gcaaaatgta aattatatat tgaatttacg caaaaaataa
     3121 catattactt ttaagatata aaaaaatatt atataatatt tttgagaagg aggtggaagg
     3181 cctatgctaa aattacataa aaaaatagct tggacaggaa tcaaaggttc agctataact
     3241 acatttatta ctgccttata taatggaagt agtgtttgga acgcgctagc tgttgctggt
     3301 attgcttttg gtggtggcgc tggtactgcg gttgcagctc ttggtcgtgc aacagtaatg
     3361 agatttatca aacgttgggg cgtacgaaaa acagctgctt ggtaaaagat aatctaattc
     3421 tttataagag aggctttctt ttttgggaaa gcctcttttt aaaaaaggag attcaatgaa
     3481 taattcaata ttttatacct atttaaaatt taatcttaga tattttatcc gtagaaaatt
     3541 tgaaattgta aaaaggtcgc gacttaatgt tactacaaaa atactgtttt taattaaatt
     3601 gattttttcg tcactattat tatttatttc aactattatg ttagctgact atttcagtga
     3661 ttatattgat tttatagaat attatttcta tgcgagtatg tttatttaca ttgtatttat
     3721 accattaata cctagaacta aattattgat caatccaatg gataaacagc tgttatatag
     3781 atctagtttg agagaagttg acatttttaa cttgatatat gcttcagacg ttttaaaaaa
     3841 gtttgttgga tattttaatt tgttgatagt tggtatggct attagtttat atcatattag
     3901 tccttttata tttaacctca aggttttttg tgcactaata tacttttcaa caatctctta
     3961 tgtaattcaa attattttta taaatattaa agtcataagc acaaaaaaat tattttctta
     4021 tcactattgt gtttttaatt ttatgatggg aagcattgtt tctgttattg gatttgtcgt
     4081 ctcatttctt ttagtaaatt tattaataaa gcccttttta gttttttcga catatgtaat
     4141 aaaaagtaag aaaacttttg aatggtatag ttattttcag gatataaaga acgaagtcat
     4201 tattattaat gaaaaagtta tgcaattatt agattatata tcacctcaca ctatttttat
     4261 gagattaaac tttgtgaata tatcatttgt gattattaca atagctttat ttatagcgtt
     4321 atattatttt aataaaatag ggttttggta tagaaaagaa gatatctatc tatcttcaac
     4381 aaatattaat ttttcgttgc caatttcaat aaaagctata acaacaatac agctaaaaca
     4441 ctggataagt aacaaagaag aagttaattt acataaacct ttcttctata ttagttattc
     4501 aatatggttc tttttagggt gtttaatcta tttttcacag atggcatata atcagttagc
     4561 taatgcagtt atttttattt tgatattaaa cactataact cgtgatagtt tttctgcggg
     4621 gacggatttt tttactaaat cattacgttt tgattcagat agaaaaagta tcggtttgta
     4681 taggatgtca aacactgatt ttaaacaaat ttacgattct aaattatctc taattcgctt
     4741 tattggtttt aaagaaacaa tacttgctat tattttatta gcaatatttt taaatcaaga
     4801 catatattta tatataattg gatttgaaat aataatcatc aatacagtaa taattcctaa
     4861 tttatcatta ttaccttcgt atttatctcc acatttcaat catcaacatt acagtgaatt
     4921 agagtctttt gaagaacaaa tttttcttga agatactgtt tttgataaag ttaagaattt
     4981 tttatcgtca tcatattttt taattctatt tgtaggttac ttatctcaac gtaattatat
     5041 tgacataatg atttttataa ttattttcaa cattttagcc ttaatacttg tttcgttgtt
     5101 tattaggttt tctaaacaaa aaataacaaa gtcttggaga aagagggatt tatatttata
     5161 gtattaaata caaaaaaatt tttattttta atatattggt gttaataata ggcggattat
     5221 tgggatgctt ggtttattac ttattaaata ttgatttagg taaaatgata gttgctcaag
     5281 atttaaattt acaagagatt ttctttcata atttaattta tttcttctct gcaatatttg
     5341 gttttctgac acttggtctg ttaaatatag gtatgttact cataaattct gggatgttag
     5401 gcttttttat agcacatgga atctatagca atcaattaaa atctattcta ttagtattag
     5461 cgccacacgc tatatttgag attttagcac ttttaattgc ttcaacattc tcattaggtt
     5521 ttttatcata cctttatcaa agaatggtaa agaaaaataa aataaaaaat aagatgttcc
     5581 ataattttgt aacaacaata ataactgtta ttgtattaac aataatcgca tcattattag
     5641 aagtttatgt aaccataaat taaggaagtg tatcatgcta gttttaaata atcttcaaaa
     5701 aaaatttact aattcaaaaa tggttttgaa taatgtgaat gctaagttta gaagtgggag
     5761 catcaattgc atagtgggag taaatggggc aggtaaaacg actttgttaa atattattag
     5821 tagtatattg atgccaacaa aaggtgatgt atatttaaat agtgaaagta tttttgaaaa
     5881 tagcacacta aaaaaagaga ttttttacac accagtaaat cccttttttt atgaaaattt
     5941 aagtgctaaa gataatttgt acttaatatg tagcctatat aatcggaaaa tagatcaaat
     6001 aactattgag aaaactatta aagatgtagg tttgaatata gaagatctaa atatacctgt
     6061 atataatttt tcaagtggta tgaagcaaaa actaaatttt gcttctatgt tattagtaga
     6121 ttcaaatgtt ttattattag atgaaccatt taatgccctt gaccatgttg ctcaaaaaaa
     6181 tttcacacga attttaaagg gattagtttc taaagaaaag ataataattt tcactagtca
     6241 tttgcctaat acaattttag aactctcaga aaatatttat ttgttaaaag atggatgttt
     6301 tacagataaa cgaaaagcac agtcatttaa tcaaaccacg ttagaaacat ggttgttaga
     6361 aagtcaaaaa gaggtgatac cttatgaaga aaaatgattt gttagtaatg agtgtagtat
     6421 atattttaac ttcagtcata atgttctaca ttaatggatt aagtaaacaa ttttttacat
     6481 atgtagttgg tttcccaatt atttattttg gttatatatg tctagttaat cttataaaaa
     6541 aaagaagccg gaataattaa aagtgaaaaa taatttgaaa atagctagag tttcactatc
     6601 tatgactcaa aaggagctag caaataaagt tggagtaact agacaaacaa tatctcttat
     6661 agaaaagggt gtacataacc cctctctatc actatgtaaa aatatttgtt cggtgttgaa
     6721 taaaaatttg gatgagatat ttggagagaa accacaataa aagagcttat tgaaagataa
     6781 tctaaaagtc gacaatatat ttcttctcag aaactgctat tattttgaaa agaaaacaca
     6841 cgtattataa atttaaaata ccgaaatata gcattattaa atcaaaaata gaattaaaaa
     6901 agaaaattaa tcgagaaaag tattaaatgt catttatttg aatgtgttaa ttatgaaaga
     6961 aaaagagtaa ttgatgttaa atatacattg actaagctaa gttga
//
LOCUS       DAPDIM010000097         6973 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000097 DAPDIM010000000
VERSION     DAPDIM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6973
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.097"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            70..720
                     /locus_tag="RFE25_002574"
     CDS             70..720
                     /locus_tag="RFE25_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001795210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excalibur calcium-binding domain-containing
                     protein"
                     /protein_id="HDU2817602.1"
                     /translation="MKITYKYRGDLPLNTENNKNQNQSVKNSERRGMLKGCGGCLISF
                     ILLIILLSACSMMFSNNDNSTSNQSSKTQLTQKDENKNEDKPEEKSETATDEDLQSTE
                     EVPANENTENNQHEIDEITTKDQSDDEINTPNVAEDKSQDDLKDDLKEKQQSSNHHQS
                     TQPKTSPSTETNRQQSFANCKQLRQVYPNGVTADHPAYRPHLDRDKDNRACEPDKN"
     gene            801..1796
                     /locus_tag="RFE25_002575"
     CDS             801..1796
                     /locus_tag="RFE25_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDU2817603.1"
                     /translation="MSNQFKSEEERRQWEQFQAFQNQQNQQHQQYGQKKSKKGWFWGC
                     GGCLVLFILIIIGISACTAGVTGNLGGNSSKEANKTHKIGETVKNGDLEVTVNSVETM
                     KSVGPSLAPTNAKGIFVVADVTIKNKGKEALTIDSSMFKLKSGDKTFEADNTGSMSAN
                     QSDNGSIENSFFLQRINPDSTAQGKIVFDVSENIANAKDKKLEVISSLFSVKKITFDL
                     SDAKKTSKAKKDKQDTEVAVASSNSDNVNYEASATTPATTSSADTDSEDSEKSSKDED
                     KQNASKSDKSSVEKSESNEETATVEPMPQSKPTTSEAPPSQNNHNENNMYDASTE"
     gene            1871..2497
                     /locus_tag="RFE25_002576"
     CDS             1871..2497
                     /locus_tag="RFE25_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817604.1"
                     /translation="MKFKAIVAITLSFSLLTACGANQHKENNSKSNDTTKKTQETDNT
                     TQSNTEKQMTPQEAEDIVRNDYKARGANENQTLNYKTNLERSNEHEYYVEHLVRDAVG
                     TPLKRCAIVNRHNGTIINIFDDMSEKDKEEFEAFKKRSPKYNPGMSDHDKTDGESEDI
                     QHHDNDNNKAIQNDTPDQKAVDKNDKNAVNKEEKHDNHAKNSAETKVK"
     gene            2538..2879
                     /locus_tag="RFE25_002577"
     CDS             2538..2879
                     /locus_tag="RFE25_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3969 family protein"
                     /protein_id="HDU2817605.1"
                     /translation="MITFENIQQLEKYTLMTMHGLFNQLKLGIISIDNAEHTLFTPYM
                     MESLSSLGVKPDIIDLIHKGTELEDFAAFNLSIEDTVTVCLQRTEELLNQYKNVEFND
                     KILINWRIIQE"
     gene            2980..3552
                     /locus_tag="RFE25_002578"
     CDS             2980..3552
                     /locus_tag="RFE25_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817606.1"
                     /translation="MEKNEYTAKYNEYSQLLDATYSQAVAYLLNKYGAVTDDYYKEKS
                     YTRFLNGEIKSISKGKYTRASEGLYCHHISEDKFQNLSDLRFISEFKYSYNVQKKENL
                     VYCDLIEHLILHAIITKESNGQFGVAGLCQMIKPTVIDWYISEYTPKPAWMQATKARA
                     YLPRILVEKLLIKIDDMLEGIEIYDFLESR"
     gene            complement(3750..4762)
                     /locus_tag="RFE25_002579"
                     /pseudo
     CDS             complement(3750..4762)
                     /locus_tag="RFE25_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611271.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4907..5002
                     /gene="pepA1"
                     /locus_tag="RFE25_002580"
     CDS             4907..5002
                     /gene="pepA1"
                     /locus_tag="RFE25_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin
                     PepA1"
                     /protein_id="HDU2817607.1"
                     /translation="MMLIFVHIIAPVISGCAIAFFSYWLSRRNTK"
     gene            5125..5226
                     /locus_tag="RFE25_002581"
     CDS             5125..5226
                     /locus_tag="RFE25_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817608.1"
                     /translation="MQGFKEKHQELKKALCQIGLMSSISEVRQLNIA"
     gene            complement(5204..5365)
                     /locus_tag="RFE25_002582"
                     /pseudo
     CDS             complement(5204..5365)
                     /locus_tag="RFE25_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066885.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5356..5850)
                     /locus_tag="RFE25_002583"
                     /pseudo
     CDS             complement(5356..5850)
                     /locus_tag="RFE25_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777469.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6302..>6973)
                     /locus_tag="RFE25_002584"
     CDS             complement(6302..>6973)
                     /locus_tag="RFE25_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDU2817609.1"
                     /translation="DQQIELEEQKLELLQQQKKCYIQKIFSQELRFKDEEGNYYKGWN
                     KKQLKDVLEFSNKRTINENEYPVLTSSRQGLILQSDYYKDRKTFAESNIGYFILPKNH
                     ITYRSRSDDGIFKFNLNLMIDVGIISKYYPVFKGIDANQYYLTLHLNYQLKKEYIKYA
                     TGTSQLVLSQKDLQNIKTKLPSYEEQQKIGDFFSEIDRLVEKQSSKVGRLKVRKKELL
                     QKMFV"
BASE COUNT         2462 a         1097 c         1064 g         2350 t
ORIGIN      
        1 tgatatagtg aaagcgtttt acacttaata actccctctt aaatgcatcc aggttttatg
       61 tagtaaatca tgaaaataac atataaatat agaggagatt tacctttgaa tacagagaac
      121 aacaagaatc aaaaccaatc tgttaaaaat tctgaaagac gcggcatgtt aaaaggatgc
      181 ggcggttgcc ttatttcttt tattttatta ataatcttat tatcagcctg ttcaatgatg
      241 tttagtaata atgacaattc cactagtaat caatcatcaa aaacgcaatt aactcaaaaa
      301 gatgaaaata aaaatgaaga taagcctgag gaaaaatcag aaacagctac agatgaggat
      361 ttacaatcaa ccgaagaagt acccgcaaat gaaaatactg aaaataatca acatgaaatt
      421 gatgaaataa caacaaaaga tcaatcagat gatgaaatta acacaccaaa cgttgcagaa
      481 gataaatcac aagacgactt gaaagatgat ttaaaagaaa agcaacaatc aagtaaccat
      541 catcaatcca cgcaacctaa gacctcacca tcaactgaaa caaacaggca acaatcattt
      601 gctaattgta agcaacttag acaagtttat ccgaatggtg tcactgccga tcatccagca
      661 tatcgtccac atttagatag agataaagat aatcgtgcat gtgaacctga taaaaattaa
      721 acaacaagcg aattgaattc aaattgtatt tagctttatg cactaatcac atagtaaata
      781 atgagggaga ttttttaggc atgagcaatc aattcaaaag tgaagaagaa cgaagacaat
      841 gggaacaatt ccaagctttc caaaatcaac aaaaccaaca gcaccagcaa tacggacaaa
      901 agaaatctaa aaaaggatgg ttctggggtt gtggtggttg tctagtatta tttattttaa
      961 ttatcatcgg tatttcagct tgtacagctg gtgtcactgg taaccttggt ggaaatagtt
     1021 ctaaagaagc gaacaaaacc cataaaatcg gtgaaactgt taaaaatggc gaccttgaag
     1081 tcactgtaaa ttcagtggaa actatgaaat ctgtaggacc gtctcttgca ccaacaaacg
     1141 ctaaaggtat atttgtcgtt gctgatgtga cgattaaaaa caaaggtaaa gaagcgttaa
     1201 caattgatag ttcaatgttt aagttaaaat ccggtgataa aacatttgaa gcagataata
     1261 caggttcaat gtctgctaat caaagtgaca atggtagtat agaaaattca tttttcttac
     1321 agcgtataaa tcctgatagc actgcacaag gtaaaattgt tttcgatgtg tcagaaaaca
     1381 tagccaacgc aaaagataaa aaattagaag ttatttctag tttatttagc gtcaagaaga
     1441 ttacatttga tttatccgat gctaaaaaaa catcaaaagc taaaaaagac aagcaagata
     1501 cagaagtagc tgttgcgagt tcaaatagcg ataatgtaaa ttatgaagct tcggctacta
     1561 cacctgctac aacttctagt gcggatactg attctgaaga tagcgaaaag tctagtaaag
     1621 atgaggataa acagaatgcg tctaaaagtg ataaatctag tgtagaaaaa agtgaatcta
     1681 atgaggaaac tgctactgta gagcccatgc cccagagcaa acctaccact agtgaagcac
     1741 cacctagtca aaataatcac aacgaaaata acatgtatga tgcttcaaca gaataaattt
     1801 tcagggtagc tcagctaccc ttctttttcg gtaaaaataa atatacatag caatataagg
     1861 agattaaaaa atgaaattca aagctatcgt tgcaatcaca ttatcatttt cactattaac
     1921 tgcctgcggt gctaatcaac ataaagaaaa taatagtaaa tcaaatgaca ctactaaaaa
     1981 gacgcaagaa actgacaaca ctacacagtc aaatacagaa aagcaaatga caccacaaga
     2041 agccgaagat atcgttcgaa acgattacaa agcaagaggt gctaacgaaa atcaaacttt
     2101 aaattataaa acaaatcttg aacggagtaa tgaacatgaa tattatgttg aacatctagt
     2161 ccgcgatgca gttggcacac ctttaaaacg ttgcgctatt gttaatcgac acaatggtac
     2221 gattattaat atttttgatg atatgtcaga aaaagataaa gaagaatttg aagcatttaa
     2281 aaagagaagc cctaaataca acccaggtat gagtgatcat gataaaacag atggtgagtc
     2341 agaagacatt caacatcatg acaatgataa taacaaagcc attcaaaatg atacaccaga
     2401 tcaaaaagcc gttgataaaa acgataaaaa tgctgttaat aaagaagaaa aacatgataa
     2461 ccatgcaaaa aattcagcag aaactaaagt taaataaggg tatactttga ttaattgtaa
     2521 tttttaggag aaaaactatg ataacatttg agaatataca acaacttgaa aaatacacct
     2581 taatgactat gcatggtctt tttaatcaac ttaaactcgg tattatttca atcgacaatg
     2641 cagagcatac cctctttaca ccttatatga tggaatcact ctcttcccta ggtgtgaaac
     2701 cagacattat cgatttaatt cacaaaggga cagagttaga agactttgca gcatttaatt
     2761 tatcaattga agatacagtt acagtctgtt tacaaagaac tgaagaacta ttaaatcaat
     2821 acaaaaatgt ggaattcaat gacaaaatat taatcaattg gcgtattata caagagtaat
     2881 agacatataa aagtcgaatg taactacgtg agtactgatt ttattctttg taaattacaa
     2941 gcatttcata tcataaagtt tgaaaagagg tatattgaag tggagaaaaa cgaatataca
     3001 gctaaatata atgaatatag tcaattatta gacgctactt actcgcaagc tgtagcatac
     3061 cttttaaata aatatggcgc tgtaaccgat gattattata aggaaaaatc atacacgcga
     3121 tttttaaatg gagaaatcaa aagtatttca aaaggaaaat acactagagc tagcgaagga
     3181 ttatattgtc atcacataag cgaagacaaa ttccaaaact tatctgacct aagattcatt
     3241 tccgaattta agtactcata caacgttcaa aagaaagaaa acttagtgta ctgtgatcta
     3301 atcgagcatt taattttaca tgcaattatt acaaaagaat ccaatggcca atttggtgtg
     3361 gctggattat gtcaaatgat caaaccaaca gtcattgatt ggtacattag cgaatatact
     3421 ccaaaaccag catggatgca agccaccaaa gcacgtgcct atttgcctag aatattagta
     3481 gagaaactac tcattaaaat tgacgatatg ttagaaggaa tagaaatata tgatttcctt
     3541 gagtctagat aaatgattaa tggagattta ttttttgctg ttgagatttt gttatagatg
     3601 tttaaacctg taattaaata tattttataa aatagaccac gcatacctat ctataaacgg
     3661 acaatgttta taaatgagtt tgcatggtct tgaattgtat taaatttctt ttggttttaa
     3721 tagttcactt agtggtatgt caacattttt tagacagttt tcatgtgtat atttttaaat
     3781 gccactggcg tcaaatactg taatgaagaa tgtggtctaa aattgttgta ccaatttaca
     3841 taatcaaata attctgtttc taactgttct aagttttcaa attgcatttg ttttacaaat
     3901 tctgttttca ttgctttcat cgttgcttcc gcaactgcgt tatcataagg acaacctttg
     3961 gtacttaatg aacgttttat tttaaatgtt tctaggactt catctatcaa atgattatca
     4021 aattctttgt ctctatcagt gtggaatagt ttgatttgtt caagattatg atttattctg
     4081 ctgattgctt ttgatactaa attggcgtcc ttatttttac ctgcactgta accaacaatt
     4141 tctctattaa atagatctat aaataaacat atgtaatgcc atgttcctcc gacttttaca
     4201 tatgtcaaat cacttactaa tgtctccatt ggttgttctc tattaaaagc gcgattcaaa
     4261 tgatttttaa ttcgtttttc attagtttct atttgatgat ttttgtattt agctttcata
     4321 taaacagaaa ctagattttt tcataatcga cctatctttt gtccagatac agtgagaccc
     4381 ttgtcattta aatgattttt aattcgtctt gtactaaaga cttttctatt agaattaaaa
     4441 atatttatgg cggcacgttc tacgtttgaa tcatctttag tgattttatt atcttttctt
     4501 tttatagaat cataataggt acttcttggt atttttagga ctttacacat tgctggtact
     4561 gaatattgat gtgcattctt ttgaatgact tctatttttg ccccataatc agctcttttt
     4621 cttcatctgt taagttatct tggtgattga atgtaccctt gttttgatgt tactttatcc
     4681 attttcctaa cgtcaaaggt gttaaatcat actcgcgtat aatttcattt cttggcttac
     4741 cattttcata taatctaacc atttataact taaactctga actaaatgtt cttctttctt
     4801 aaattaacaa aatctactct catagaattt gtccaattag atgatataat agtagagtcg
     4861 cctatctctc aggcgtcaat ttagacgcag agaggaggtg tataaggtga tgcttatttt
     4921 cgttcacatc atagcaccag tcatcagtgg ctgtgccatt gcgttttttt cttattggct
     4981 aagtagacgc aatacaaaat aggtgacata tagccgcacc aataaaaatc ccctcactac
     5041 cgcaaatagt gaggggattg gtgtataagt aaatacttat tttcgttatc tcaattatac
     5101 tgctaatctt tctctttgta aaatatgcaa ggttttaaag agaaacatca agaactaaaa
     5161 aaggctctat gccaaattgg cctgatgagt tcaatatcgg aagttaggca actaaacatt
     5221 gcttagcttc ctttttactt tttggagcgt aaagttttga acataataat attcgatttc
     5281 gcaaatgatt ataacttcct taaccaaaag atgtacgttt aattaatttt attttgttgt
     5341 ttatcccttc taaaggacca tttgattatc cttcgtttta aagttaatgc cttctttcca
     5401 gtcaaactgt gcttgatgac tggcttttgt ctcgaatctc gttttgcctt taggcgacaa
     5461 ccgttgataa cctttcataa aataacgatt aaattcatca tgtttaagga tataagctct
     5521 aaatgtagaa tatgcacagg ttaatccatg tttatctttc aaatattgcc aaagaataag
     5581 cttatagtag aacttttgtt cactagagtc tgaaagtaat ttttcgatga taggataata
     5641 cttgtcaata atagactgac gatttctctt tttggttggc tcaaagccat ttaaatattt
     5701 atcaactgtt cttctataaa cacccatgtg tctcgctatt tcacttttgt ttattttcat
     5761 gtttaagttc tccatgacaa tttttaattt tggtaaatct gtaagagtag taacttcaaa
     5821 atcagtattt atgtctaaag ataatttcat tgttgttcat ctcaataaaa ttatctatag
     5881 gtttttaaaa attgtacatg tttaaacaat caaaagtgca cattattaaa ttatcatttc
     5941 cagttaaact gtcttgatga ttgaatgact cagtattttg gttttgtttt gtctaatttg
     6001 agagagttaa tgatgttaga ttatattctc gtataatttc gtttctaggc ttaccatttt
     6061 cataaagttt aattatttta atttaaatta tttactaaaa gctcttcagt ctcttgtcac
     6121 aataaaatcg cctaacctct tagtttaaca atatctattc ccatagaatt tgtccaacta
     6181 agtgtagacg attcactaaa ctccaaaaaa ataaatccca aattataata gtttcaatat
     6241 taatatatta caatttattc atagaatttt tatcatttta attaataggc tgttatctgg
     6301 attaaacaaa cattttttgt aatagttctt ttttacgtac ttttaatcgt ccgacttttg
     6361 aagattgttt ttcaaccaat ctatctattt cactgaaaaa atcaccgatt ttttgttgtt
     6421 cttcataaga tggcaattta gtctttatgt tttgcaagtc tttttgtgag agtaccaatt
     6481 gtgatgtacc agttgcatat ttaatatatt cttttttcag ttgatagttt aagtgtaatg
     6541 ttaaataata ttgatttgca tctatccctt taaagacagg gtaatattta ctaataatac
     6601 ctacatcaat cattagattt aaattaaact taaaaattcc atcgtcgctt cttgaacggt
     6661 atgttatatg atttttaggg agtatgaaat acccaatatt actctctgca aaagttttcc
     6721 tatctttata gtagtctgac tgaagtatta aaccttgtct tgacgatgtt aaaacaggat
     6781 attcattttc attaatagtt cttttattac taaattctaa tacatctttt aattgctttt
     6841 tgttccatcc tttatagtaa ttaccttctt catctttgaa tcgtaattct tgtgagaaga
     6901 ttttctgtat atagcatttt ttctgttgtt gaagtaattc aagtttttgt tcttctaatt
     6961 caatttgttg gtc
//
LOCUS       DAPDIM010000098         6936 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000098 DAPDIM010000000
VERSION     DAPDIM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6936
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.098"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            23..775
                     /gene="sarS"
                     /locus_tag="RFE25_002585"
     CDS             23..775
                     /gene="sarS"
                     /locus_tag="RFE25_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarS"
                     /protein_id="HDU2817610.1"
                     /translation="MKYNNHDKIRDFIIIEAYMFRFKKKVKPEVDMTIKEFILLTYLF
                     HQQENTLPFKKIVSDLCYKQSDLVQHIKVLVKHSYISKVRSKIDERNTYISISEEQRE
                     KIAERVTLFDQIIKQFNLADQSESQMIPKDSKEFLNLMMYTMYFKNIIKKHLTLSFVE
                     FTILAIITSQNKNIVLLKDLIETIHHKYPQTVRALNNLKKQGYLIKERSTEDERKILI
                     HMDDAQQDHAEQLLAQVNQLLADKDHLHLVFE"
     gene            1196..2647
                     /gene="spa"
                     /locus_tag="RFE25_002586"
     CDS             1196..2647
                     /gene="spa"
                     /locus_tag="RFE25_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal protein A"
                     /protein_id="HDU2817611.1"
                     /translation="MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQ
                     NAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNK
                     DQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNK
                     EQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNK
                     EQQNAFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNKKP
                     GKEDGNKKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNNKPGKEDGNKPGKEDNKKPG
                     KEDGNKPGKEDNNKPGKEDGNKPGKEDNNKPGKEDGNKPGKEDGNKPGKEDGNGVHVV
                     KPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALP
                     ETGEENPFIGTTVFGGLSLALGAALLAGRRREL"
     gene            complement(2976..4568)
                     /locus_tag="RFE25_002587"
     CDS             complement(2976..4568)
                     /locus_tag="RFE25_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDU2817612.1"
                     /translation="MTLLTVNPFDNVGLSALVAAVPIILFLLCLTVFKMKGIYAALTT
                     LVVTLIVALFVFELPARVSAGAITEGVVAGIFPIGYIVLMAVWLYKVSIKTGQFSIIQ
                     DSIASISEDQRIQLLLIGFCFNAFLEGAAGFGVPIAICAVLLIQLGFEPLKAAMLCLI
                     ANGAAGAFGAIGLPVSIIDTFNLSGGVTTLDVARYSALTLPILNFIIPFVLVFIVDGM
                     KGIKEILPVILTVSGTYTGLQLLLTIFHGPELADIIPSLATMVVLAFVCRKFKPKNIF
                     RLEASEHKIQKRTPKEIVFAWSPFVILTAFVLVWSAPFFKKLFQPGGALESLVIKLPI
                     PNTVSDLSPKGIALRLDLIGATGTAILLTVIITILITKLKWKSAGALLVEAIKELWLP
                     ILTISAILAIAKVMTYGGLTVAIGQGIAKAGAIFPLFSPVLGWIGVFMTGSVVNNNTL
                     FAPIQATVAQQISTSGSLLVAANTAGGVAAKLISPQSIAIATAAVKKVGEESALLKMT
                     LKYSIIFVAFICVWTFILTLIF"
     gene            complement(4830..5303)
                     /locus_tag="RFE25_002588"
     CDS             complement(4830..5303)
                     /locus_tag="RFE25_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDU2817613.1"
                     /translation="MSKIRSFTILSLLIYLAMMCYTVVTYSKLPTKVPIHYNLAGDAD
                     NFADKWVLLLINSAFIVIWLIFFIAGRYYERFAKWSHYNHTPREIRAIKLFLSTLNLE
                     IMSYMSIFTVLEIWQIQHHHQLNLLWFNMIFIIIIGLTLVIFCLLPTIHKMRDSQ"
     gene            complement(5493..6890)
                     /locus_tag="RFE25_002589"
                     /pseudo
     CDS             complement(5493..6890)
                     /locus_tag="RFE25_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
BASE COUNT         2551 a         1238 c          972 g         2175 t
ORIGIN      
        1 gcatatacaa ggagataaaa caatgaaata taataaccat gacaaaatta gagattttat
       61 aatcattgaa gcatatatgt ttcgttttaa gaaaaaagtc aagcctgaag tcgatatgac
      121 tataaaagaa tttatattac tgacttattt atttcatcag caagaaaaca cacttccatt
      181 taagaagatt gtttcagatt tatgttataa acaatcggat ttagtacagc atataaaagt
      241 acttgtgaaa cattcatata ttagtaaagt tcgaagtaaa attgatgagc gtaatactta
      301 catttcaata tctgaagaac aacgagagaa aattgcagaa cgtgttacat tgtttgatca
      361 aatcattaaa caatttaacc ttgcagatca aagtgaatca cagatgatac caaaagatag
      421 taaagaattt ctaaacttga tgatgtatac aatgtatttc aagaatatta tcaaaaaaca
      481 tctaacatta agttttgtag aattcacaat tctagctatt atcacttctc aaaataaaaa
      541 catcgttctt cttaaagatt taattgaaac aatccaccat aaataccctc aaactgttag
      601 agctctcaat aatttaaaaa agcaaggcta tctaataaaa gaacgctcaa ctgaagatga
      661 aagaaaaatt ttaattcata tggatgacgc gcagcaagac catgctgaac aattattagc
      721 tcaagtgaat caattattag cagataaaga tcatttacat cttgtttttg aataatatct
      781 ctattacgca agtgtgctgt attctaaagt gcacttgtgt tttctatttt ttaataaaac
      841 ctcagcacat aatgaacaac tttctatttt ctatatcact taaaaccatt tccgaaatta
      901 aacctcagca cattcaaagc cccactttat tcttaaaaat attttttaac tcatatgtat
      961 taaaccgctt tcattataaa aaatatctct atattttatc tgtttttatt aatcgaaata
     1021 gcgtgatttt gcggttttaa gccttttact tcctgaataa atctttcagc aaaatattta
     1081 ttttataagt tgtaaaactt acatttaaat ttaattataa atatagattt tagtattgca
     1141 atacataatt cgttatatta tgatgacttt acaaatacat acagggggta ttaatttgaa
     1201 aaagaaaaac atttattcaa ttcgtaaact aggtgtaggt attgcatctg taactttagg
     1261 tacattactt atatctggtg gcgtaacacc tgctgcaaat gctgcgcaac acgatgaagc
     1321 tcaacaaaat gctttttatc aagtgttaaa tatgcctaac ttaaacgctg atcaacgtaa
     1381 tggttttatc caaagcctta aagatgatcc aagccaaagt gctaacgttt taggtgaagc
     1441 tcaaaaactt aatgactctc aagctccaaa agctgatgcg caacaaaata acttcaacaa
     1501 agatcaacaa agcgccttct atgaaatctt gaacatgcct aacttaaacg aagcgcaacg
     1561 taacggcttc attcaaagtc ttaaagacga cccaagccaa agcactaatg ttttaggtga
     1621 agctaaaaaa ttaaacgaat ctcaagcacc gaaagctgat aacaatttca acaaagaaca
     1681 acaaaatgct ttctatgaaa tcttgaatat gcctaactta aacgaagaac aacgcaatgg
     1741 tttcatccaa agcttaaaag atgacccaag ccaaagtgct aacctattgt cagaagctaa
     1801 aaagttaaat gaatctcaag caccgaaagc ggataacaaa ttcaacaaag aacaacaaaa
     1861 tgctttctat gaaattttac atttacctaa cttaactgaa gaacaacgta acggcttcat
     1921 ccaaagcctt aaagacgatc cttcagtgag caaagaaatt ttagcagaag ctaaaaagct
     1981 aaacgatgct caagcaccaa aagaggaaga caacaaaaaa cctggtaaag aagacggcaa
     2041 caaaaaacct ggtaaagaag acggcaacaa gcctggtaaa gaagacaaca aaaaacctgg
     2101 taaagaagac ggcaacaagc ctggtaaaga agacaacaac aaacctggca aagaagacgg
     2161 caacaagcct ggtaaagaag acaacaaaaa acctggtaaa gaagacggca acaagcctgg
     2221 taaagaagac aacaacaaac ctggcaaaga agacggcaac aagcctggta aagaagacaa
     2281 caacaagcct ggtaaagaag acggcaacaa gcctggtaaa gaagacggca acaaacctgg
     2341 taaagaagac ggcaacggag tacatgtcgt taaacctggt gatacagtaa atgacattgc
     2401 aaaagcaaac ggcactactg ctgacaaaat tgctgcagat aacaaattag ctgataaaaa
     2461 catgatcaaa cctggtcaag aacttgttgt tgataagaag caaccagcaa accatgcaga
     2521 tgctaacaaa gctcaagcat taccagaaac tggtgaagaa aatccattca tcggtacaac
     2581 tgtatttggt ggattatcat tagccttagg tgcagcgtta ttagctggac gtcgtcgcga
     2641 actataaaaa caaacaatac acaacgatag atatcatttt atccaaacca attttaactt
     2701 atatacgttg attaacacat tcttatttga aatgataaga atcatctaaa tgcacgagca
     2761 acatcttttg ttgctcagtg cattttttat tttacttact tttctaaaca acttctgaaa
     2821 cgcctcaaca ctttctactc tgattacata tacgacattt ttagacatta aaaaatcgaa
     2881 ctagacaaga tgctcattgc atttcgtact agttcgattc atgaataatt agatttaaaa
     2941 tgtcatttga atccaagtga caacattatt tatatttaga atattaacgt tagtataaac
     3001 gtccaaacac aaataaaggc aacaaatata atactgtatt ttaacgtcat ttttaataat
     3061 gcagattctt caccaacttt tttaacagct gcagtcgcaa tggcaattga ttgtggtgaa
     3121 ataagtttcg ctgctacacc acctgcagtg ttagctgcca caagtaatga accgcttgtt
     3181 gaaatttgtt gtgccactgt cgcttgaata ggtgcgaata aagtattgtt atttacaact
     3241 gaaccagtca taaacacacc aatccaacct aatactggag agaataatgg gaaaattgct
     3301 cccgctttag caataccttg tccaattgct acagtcaaac caccgtatgt cataacttta
     3361 gcaatagcta ggatagctga aattgtaagg atcggtaacc ataattcttt aattgcttcg
     3421 accaataaag cacctgcact tttccatttt aacttcgtaa ttaaaattgt aataattact
     3481 gttaataaaa tcgctgtccc agttgcacca attaaatcga gacgcaacgc aattccttta
     3541 ggcgataaat cactcacagt atttggaatt ggcaatttta ttactaaact ttcaagtgca
     3601 cctccaggtt ggaataattt tttgaagaat ggtgcactcc atactaatac aaaggcagtt
     3661 aaaattacga acggactcca agcaaagaca atttctttag gcgttcgttt ttgaatttta
     3721 tgttcagacg cttccaatct gaaaatgttt ttcggtttaa atttacgaca aacaaatgct
     3781 aacaccacca ttgttgctag tgatggaata atgtctgcta gttctggacc atggaatatt
     3841 gttaataata attgtaatcc agtatatgta ccactcactg ttaaaatgac aggtaaaatt
     3901 tctttaatac ctttcatacc atctacaatg aatactaaaa caaatggaat aataaagttt
     3961 aaaattggaa gtgttaatgc tgagtatctc gcaacatcta atgttgtaac gcctccactt
     4021 aagttaaacg tatcaataat actaactggt aaaccaattg caccaaaggc acccgccgca
     4081 ccattagcaa ttaaacataa catcgctgct tttaatggtt caaatccaag ttgaattaat
     4141 aatactgcac aaatcgcaat tggcacacca aatcctgctg caccttctaa aaatgcgttg
     4201 aaacaaaatc caattaataa tagttggatt ctttggtcct ctgaaatact tgcaatacta
     4261 tcttgaataa tagaaaattg tcctgtttta atagaaactt tatataacca aactgccatt
     4321 aaaacgatat atcctattgg gaaaataccg gcaacaacgc cttctgtaat cgcacctgct
     4381 gatacacgcg ctggtaattc aaatacaaat aaagccacaa tcaatgtaac aaccaaagtt
     4441 gtcaatgctg cataaatgcc tttcatttta aaaacggtta agcataataa aaataaaata
     4501 ataggtactg ctgcaactaa ggctgataat ccaacattat cgaatggatt tacagtaagt
     4561 agtgtcataa tgactccctc tctttatata aaatatttat cattctgatt aatctacaac
     4621 ctatttcaac ttatattttg cgatgatcac atatttaaaa tgtaacactc ctatatgtga
     4681 caggcaatcg aatttttaca aaaagttcac aaaatataca caatatttaa ctataataaa
     4741 taatatatca ttttaattat aaatactaga tattatttat aataatatca ggaatccgct
     4801 tcaaaaatgc atcatgacag tttatatttt tattgagaat ctctcatttt gtgaattgta
     4861 ggaagtaaac aaaatatgac aagcgttaaa ccaatgataa tgataaatat catattaaac
     4921 catagtaaat ttaattgatg atggtgttgt atttgccaaa tttctaatac tgtgaagata
     4981 gacatatagc tcataatctc taaatttaac gtacttaaaa ataatttaat cgctcgaatt
     5041 tcacgtggtg tatgattata atgtgaccat ttggcaaatc gttcatagta tctacctgca
     5101 atgaaaaata taagccaaat cactataaat gcgctattta tcaaaagcag tacccattta
     5161 tcagcaaagt tatcagcatc ccctgctaaa ttatagtgaa taggtacttt ggttggtaat
     5221 tttgaatagg tcactactgt atagcacatc atagctaagt aaataagtag acttaatatt
     5281 gtaaaagacc tgattttaga cattctatcg cctctttctt tacattttat gtataacact
     5341 ctgcctattt taccttttaa ttacattacc ccaaacgatt aaacaatatg taatgatact
     5401 ataattgcgt caggagtatc cgcttgttaa atgtgcatag cttatattta gctgtttaac
     5461 atgccacata atgattcgaa ttattgtttt aattaaacct ttttcacata tgtataaatt
     5521 ttatagagcg catgcttaat attttcattt gattcaaagg caaaagatag ccttatactc
     5581 ttttctttac tgccataaat gtaacccgga ttgattaata ttttttcttt acttaacaat
     5641 tcgtaaaata aatatttaat atctatatct attttaaaga ctaaccatac aaaataacct
     5701 ccacttggaa cctcccaatg tgctatatcc ttaaataaat tattgaggat gtttaacata
     5761 aagtctcgtt tatcttttaa aacatacctt aactttacta agtgtttatc ataagactta
     5821 tttttcaaca tctcatatac aaccatttgt gacaaaatac tggatccata gtcaatttgc
     5881 attcttacat ctgccaattg ctctattatt ttttcagaag caacaatcca acctattctt
     5941 attgctggtg caatcgtttt tgaaaaactg cttatatgta taacttttcc caatttatca
     6001 taagttttga tagcaggagt tggatcgcta aagaaaatat ctctaaagat atcatcttca
     6061 atgataggaa tattatgtct ttcgctataa gtaattatat ttttcttttg ctcattcgtt
     6121 aaagaacgac ctgtcgggtt attaaaccta ggttctatat aaatcgcttt atttttaaaa
     6181 ttaataaatc tatcaatgat ggtattaatt tcattaattt gattataagg aacatcaata
     6241 tgtctaaaat tcaattgctc aaaaacattt gtagagtgaa tatatgatgg tgtattcgaa
     6301 attattatgg catcttgacc taaaaaccca atagataaaa gttgaatggc atgtaaagcg
     6361 cctgaagtga tcattacatt ttctctacct acatttatac cttgctttga cattcgttca
     6421 acgataatat ctcttaactt gatataacca tagccattat tataaccaaa agataagtct
     6481 tcaatatgac tggctgtatt agacatggct tttttcaatt gaatatgtgg cattaacgat
     6541 atacccaatt cacctttact tatatgtata tacgaatcat ctgtctcaat tttattaatt
     6601 aattgcaccg tatactgact tctttgttga gaggaccata acatcatttc agaccactta
     6661 tttgtaatat gtgcttcatt caaatagtca ttaacatatg ttccactccc cactttagta
     6721 tagataaatc cttcagcctc taataactca atacttttaa taatcgtcac tctatttacg
     6781 ttgtattgta tcgccaactg cctctgtgga ggtatcttca ttccataaaa ccaatcccct
     6841 gtgattattt tatctcttat gtcactagca atatcttaat atttagccat cttctccctc
     6901 ccttttaaaa ttggataggt aaatccattc aaaatt
//
LOCUS       DAPDIM010000099         6890 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000099 DAPDIM010000000
VERSION     DAPDIM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6890
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.099"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            1..831
                     /locus_tag="RFE25_002590"
                     /pseudo
     CDS             1..831
                     /locus_tag="RFE25_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837660.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
     gene            888..1862
                     /gene="holA"
                     /locus_tag="RFE25_002591"
     CDS             888..1862
                     /gene="holA"
                     /locus_tag="RFE25_002591"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDU2817614.1"
                     /translation="MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYE
                     TEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENL
                     IVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALD
                     LFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRK
                     KEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYR
                     VKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL"
     gene            complement(1907..2158)
                     /locus_tag="RFE25_002592"
     CDS             complement(1907..2158)
                     /locus_tag="RFE25_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDU2817615.1"
                     /translation="MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNAD
                     NKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK"
     gene            2504..4327
                     /gene="lepA"
                     /locus_tag="RFE25_002593"
     CDS             2504..4327
                     /gene="lepA"
                     /locus_tag="RFE25_002593"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDU2817616.1"
                     /translation="MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRD
                     MQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMI
                     GLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISS
                     IRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDD
                     SRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLE
                     FEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVT
                     VDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVN
                     IVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFI
                     VHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGG
                     DISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE"
     gene            4893..6017
                     /locus_tag="RFE25_002594"
     CDS             4893..6017
                     /locus_tag="RFE25_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDU2817617.1"
                     /translation="MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMS
                     TAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQL
                     LEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPK
                     QTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLL
                     MSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPV
                     NHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFG
                     QTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND"
     gene            6118..>6890
                     /gene="hrcA"
                     /locus_tag="RFE25_002595"
     CDS             6118..>6890
                     /gene="hrcA"
                     /locus_tag="RFE25_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDU2817618.1"
                     /translation="MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRN
                     EMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQY
                     DVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
                     HVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMN
                     NHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIES"
BASE COUNT         2594 a          883 c         1243 g         2170 t
ORIGIN      
        1 taataacgtt tccaacaaat tcacatcaca aaattacaat gttaaatgtg gggcagggag
       61 acagtatttt atatgaaggc ggtaagaacc aaaatgtctt gattgataca ggtgggaaag
      121 tgattgatga tactaaacaa cctagttatt caatttctta aatatcatat tttaccaacg
      181 ctaaatgaaa gagggataaa tgaattagag tatctaattt taacacatcc acacaatgac
      241 catattggtg aagtggaata tattattagt catattaaaa ttaaacatat agtgatatac
      301 aataagggat atagtagtaa tacattgatg ttattatcga aattaagcca taagtacaac
      361 attaaactta tggatgtaag acaagttagt agttttaaac ttggagatag tagttttcta
      421 ttttttgata gttttattcc aaatagccga gataaaaatg agtattcgat tattactatg
      481 attacatatc aaaataaaaa agttttatta atgggcgatg ctagtaaaaa taatgaatct
      541 ttactactaa aaaaatataa cttgccggag attgatattt taaaagtagg acatcatggg
      601 agcaagacaa gtagttctaa agaatttata gagatgatta agcctaaaat aagtttgatt
      661 tcttctggga agaacaatat gtatcatctt cctaatatag aagttgttaa acgattgcaa
      721 aggattcgca gtcgcattta caatagtcaa caaaacggtc aagttacaat tgacttagat
      781 gataatttaa aagttgattc aaactcttat ggaaatgcaa gtggtttata gatacagaaa
      841 catgatataa tctattgatg tgtcaaacga atgaaagggt gtaatgaatg agcgacaata
      901 ttgtagctat ttatggagat gtgcctgaat tggttgaaaa acaaagtgca gaaatcatat
      961 cacaattttt gaaaagtgat agagatgact ttaactttgt gaaatataat ttatacgaaa
     1021 cagagattgc accaattgtt gaagaaacat taacattgcc tttcttttca gataaaaaag
     1081 caattttggt taaaaatgca tatatattta caggtgaaaa agcgccaaaa gatatggctc
     1141 ataatgtaga tcaattaata gaatttattg aaaaatatga tggcgaaaat ttgattgtct
     1201 ttgagatata tcaaaataaa cttgatgaaa gaaaaaagtt aactaaaact ctaaaaaagc
     1261 atgcaaggct taaaaaaata gagcaaatgt ctgaagaaga aataaaaaaa tggattcaaa
     1321 gtaaattaaa tgagaatttc aaagatatca aaagagatgc attagattta tttattgagt
     1381 tgacaggtat taactttaat attgtctcac aagagataga aaagttgatt ttatttttag
     1441 gcgatagacc aacaattaat aagcaggatg ttaaccaaat tattaataga agtttagagc
     1501 aaaatgtatt tttactgact gaatacattc agaaaagaaa gaaagaacaa gcaattcatt
     1561 tagtaaaaga tttaataact atgaaagaag aaccaattaa attacttgca ctaattacaa
     1621 gtaattaccg attattttat caatgtaaga ttctgagtca aaaaggatat agtggacagc
     1681 aaattgctaa aacaatagga gtgcatccat acagagtaaa attagcgtta ggacaagtaa
     1741 gacattatca acttgatgaa ttattgaata ttgtagatgc ttgtgcggaa actgattata
     1801 aacttaaatc atcatatatg gataaacagt taatactgga attattcatt ctatctttat
     1861 aaaaaataaa agttcaagca tgcgcttgaa cttttattta aaaagattat ttatttgcag
     1921 tcattaattg tgatttaata cggtcagctt tgtttgaatg tattaaatta ctttgagcag
     1981 ctttgtctac taacttaact gctaagctta ctaattcatt tttattatca gcgttatttg
     2041 aaacagctgt tttagcgttt ttaactgctg tacgcattgc actcttttgt gaaatgttgc
     2101 gtgcttcagc tttttcagtt gtttttacac gtttaattgc agatttgata tttgccattt
     2161 ctgtcacctc ctaaaagtga gttcatctta tcaaaatttt atttgattac aacaagaaat
     2221 attttaacaa aagtctaacc gttgtgcaat catttatttg atggggttag cttaaaattt
     2281 tgcagattta ataaattgtg ttggaaacac aatcaatacg ttttataatt ataagtacgt
     2341 aattaacata ttaacatatc gcaagtatgt atttaaataa agattgttat aatttcaaag
     2401 ttcatccaag attatggcgt ttgcatttac ctattaaaaa cgttattata tcaaagatgc
     2461 gaaagataat acgggtttat tttatgaaag tgagaaggat aaaatggata atgagcaacg
     2521 cttaaaaaga agagagaata taaggaattt ctcgattata gcacatattg accacggaaa
     2581 atctacattg gctgatagaa ttttagaaaa taccaaatca gttgaaacaa gagatatgca
     2641 agatcagtta ctagattcaa tggatttaga aagagaacgt ggtattacaa tcaaattaaa
     2701 cgcagttcgt ttaaagtacg aagctaaaga tggaaatact tatacattcc atttaatcga
     2761 tacgcctgga cacgtcgatt ttacatatga agtgtcacgt tctttggcag cttgtgaggg
     2821 tgcgatttta gtagtagatg cggctcaagg tatcgaagca caaacattag caaatgttta
     2881 tttggcatta gataatgagt tagagttatt gcctgttatt aacaaaattg atttacctgc
     2941 tgcagaacct gaacgcgtga aacaagaaat tgaagatatg ataggtttag accaagacga
     3001 tgttgtttta gcaagtgcta aatctaacat tggaattgaa gagatactag agaaaatagt
     3061 tgaagttgtg ccagctccag atggtgaccc agaagcacca ctaaaagcat taatatttga
     3121 ttctgagtat gatccatata gaggggtaat ttcatcgata agaattgtag acggtgttgt
     3181 taaagctgga gataaaattc gaatgatggc cactggtaaa gagttcgaag taacagaagt
     3241 tggaattaat acacctaagc agcttccagt tgatgaatta acagttggtg atgttggtta
     3301 tattattgca agtattaaaa atgttgatga ttctagggtt ggtgacacca tcacattagc
     3361 tagtagacct gcatcagaac cattgcaagg ttataagaaa atgaatccaa tggtatattg
     3421 cggactgttc ccaatagata acaaaaatta taatgattta agagaagcat tagaaaaatt
     3481 acaattgaat gatgcatcat tagaatttga gcctgaatcg tcacaagcat taggttttgg
     3541 ttatagaact ggtttcttag gtatgttaca catggaaata attcaagaaa gaattgaaag
     3601 agaatttggc attgaattaa ttgcaacagc accatctgta atttatcaat gtattttaag
     3661 ggacggttca gaagtgacgg ttgataaccc agcacaaatg ccagatcgtg ataaaattga
     3721 taaaatattt gagccatatg ttcgtgcaac tatgatggtt ccaaatgact atgtaggtgc
     3781 agtaatggaa ttatgtcaac gtaaacgtgg acaatttata aatatggact atttagatga
     3841 tattcgtgta aatattgttt atgaattacc tttagctgaa gttgtatttg atttcttcga
     3901 tcaacttaaa tctaatacta aaggatatgc atcatttgat tatgaattca tcgaaaataa
     3961 agaaagtaat ttagttaaga tggatatttt attaaacggt gataaagtgg atgcgctaag
     4021 cttcatagtt catagagatt ttgcatatga acgtggtaaa gcattagttg aaaaacttaa
     4081 aacgttaatt ccaagacagc aatttgaagt acctgtacag gctgcaatag gacaaaaaat
     4141 tgtagcgcgt acaaatatta aatcaatggg taaaaacgtt ttagctaaat gttatggcgg
     4201 tgacataagc cgtaaacgta aattacttga aaaacaaaaa gcaggtaaag ctaagatgaa
     4261 agcagttggt aatgttgaaa ttccacagga tgctttcttg gctgtattga aaatggatga
     4321 cgaataagtt tttaaaaaat ttattaacaa tttacaatga ataaagttta ataactaaaa
     4381 agagggagcc taggataaat taacgtcctg ggctttacaa tgttatattg gcagtcatcg
     4441 acagagttaa aatgagctta taacaatggg gccccaacac agagaatttc gaaaagaaat
     4501 tctacaggca atgcaagttg gggtgtgggc cccaacacag agaaattgga ttcccaattt
     4561 ctacagacaa tgcaagttgg ggtgggacaa cgaaataaat tttgcgaaaa tatcatttct
     4621 gtcccactcc cttatgcatg agttttactc atgtaatttt atttttaagg acatattaca
     4681 tctggctaat gtgtaagagc cactacataa taaatcatta gtggttcttt attatttcta
     4741 tctcactccc tctaaacaag aataaatatc aaaatgaatc gatatattag acaaccattg
     4801 attaaacgtt aaagttaaaa gtaagaataa cagcagatag tccaacagga tgtagccgat
     4861 tggataaaca gtctgagaag cggggcatta aaatgacggt acaaagtgca tatatacata
     4921 ttccattttg tgtaagaata tgtacatatt gtgatttcaa taaatatttt atacagaatc
     4981 aacctgtaga tgagtactta gatgcactaa taacagaaat gtctacagca aaatatagga
     5041 acttaaagac catgtatgta ggtggcggca caccaacggc cctttctatt aatcagttgg
     5101 aaagattact taaagcaata cgtgatacgt ttacaatcac aggcgagtat acatttgaag
     5161 caaatcctga tgagttaact aaagagaaag tccaactatt agagaaatat ggagtaaata
     5221 gaatttcaat gggcgttcaa acattcaaac cggagttatt gtctgtttta ggtagaacgc
     5281 acaatactga agatatttac acttcggtgt taaatgctaa aaacgcaggt attaaatcaa
     5341 tcagtttaga tttaatgtat catttaccga aacagacgat tgaagatttt gaacaaagtt
     5401 tagatctagc tttagatatg gatattcaac atatttcgag ttacggctta atacttgaac
     5461 ctaaaaccca attttataat atgtatagaa aagggttgct taaacttcct aatgaggatt
     5521 taggtgctga catgtatcag ttgttgatgt ctaagataga acaatctcct ttccatcaat
     5581 acgaaatatc taattttgca ttagatggcc atgaatcaga acataataag gtttactggt
     5641 ttaatgagga atattatgga tttggagcag gtgcaagtgg ttatgtagat ggtgtgcgtt
     5701 atacgaatat caatccagtg aatcattata tcaaagctat aaataaagaa agtaaagcaa
     5761 ttttagtatc aaataaacct tctttgactg agagaatgga agaagaaatg tttcttgggt
     5821 tgcgtttaaa tgaaggtgtg agtagtagta ggttcaaaaa gaagtttgac caatctattg
     5881 aaagtgtctt tggtcaaaca ataaataatt taaaagagaa agaattaatt gtagaaaaga
     5941 acgatgcgat tgcactaaca aagcgaggga aagtcatagg taatgaggtt tttgaagctt
     6001 tcctaataaa tgattaaaaa aaattgaaat ttcgagtctt taacattgac ttactttgac
     6061 caatttgata aattataatt agcacttgag ataagtgagt gctaatgagg tgaaaacatg
     6121 attacagata ggcaattgag tatattaaac gcaattgttg aggattatgt tgattttgga
     6181 caacccgttg gttctaaaac actaattgag cgacataact tgaatgttag tcctgctaca
     6241 attagaaatg agatgaaaca gcttgaagat ttaaactata tcgaaaagac acatagttct
     6301 tcagggcgtt cgccatcaca attaggtttt aggtattatg tcaatcgttt acttgaacaa
     6361 acatctcatc aaaaaacaaa taaattaaga cgattaaatc aattgttagt tgagaatcaa
     6421 tatgatgtat catcagcatt gacatatttt gcagatgaat tatcaaatat atctcaatat
     6481 acaactttag ttgttcatcc taatcataaa caagatatta tcaataatgt acatttgatt
     6541 cgtgctaatc ctaatttagt tataatggtt atcgtatttt catcaggtca tgttgagcat
     6601 gtacatcttg cttcagacat accgtttagt aatgataaac taaatacaat atcaaatttt
     6661 gttactaaca aactaactga gtttaatcag aatttacaag atgatattgt ctcttttgtt
     6721 caatcagagc aggaagaaat atttatcaat aaattgataa atacgatgaa taatcatatt
     6781 tctaatcaaa gtaatagcat ttatatgggt ggaaaggtta aacttattga tgcattgaat
     6841 gaaagtaatg tatcttcaat tcagcccatt ctacaatata tagaatcaaa
//
LOCUS       DAPDIM010000100         6750 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000100 DAPDIM010000000
VERSION     DAPDIM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6750
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.100"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            120..551
                     /locus_tag="RFE25_002596"
                     /pseudo
     CDS             120..551
                     /locus_tag="RFE25_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086052.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            588..1376
                     /locus_tag="RFE25_002597"
     CDS             588..1376
                     /locus_tag="RFE25_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HDU2817619.1"
                     /translation="MTTFDAKKLKKEYLDWYNQILEFSNLSNNSVKIDTPFKDNSLDN
                     LKIYALYDQSRDMITLTDDGYTIFGLENNGVSINKFKKRKKIFEEHLSAYGIKYNDKT
                     HEIFVQTNFKNFNKSKHNLLQCLIFVNDMYLLSNPKSQNIFTEDVANKLDEHNIYYGR
                     DIPIIGSSGVVHNFDFFISAKKNQKEKFINVFSNPNNSMIIKSKITDAMQAKKIKRHR
                     QNEFIFILNDSKKEINEHNKNLLHENYISTIDYSELDEKIGLLI"
     gene            2210..2704
                     /locus_tag="RFE25_002598"
     CDS             2210..2704
                     /locus_tag="RFE25_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001253430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817620.1"
                     /translation="MRRLLSLLLASTMILVACGNANNENKKKEDEKKSEVKKEATKNN
                     DKPKNEKKNQDINKNNNEQVQNVNNKQPVLNNNSNHNNQQQSNKNNYTVIENGNTVTE
                     IYNGQSHTTTNNPIREEYVEGETDPIYKREYKHFYTPEEAQRAQENSDQILREMGLEP
                     ERYE"
     gene            2782..3018
                     /locus_tag="RFE25_002599"
     CDS             2782..3018
                     /locus_tag="RFE25_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817621.1"
                     /translation="MIRFDVNGSDHANPPNNERIPTPHIHIYTEEYNNGGIAIPLKDI
                     EDLELTDEIIESLDFFMKYTNIKHDNVIKEPRLL"
     gene            3039..3815
                     /locus_tag="RFE25_002600"
     CDS             3039..3815
                     /locus_tag="RFE25_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HDU2817622.1"
                     /translation="MKTIEERMNEYFNWLKQNYIFKELDSSTEITTTFKNHLNDFIRI
                     YADTLPNNEICLSDDGLTINELEMLGIDINTKTRTKLIQNILNQFNLKLVDKEITADV
                     KNESFAQSKHNLIQGILKIYDLTLTTKSNVTNIFYEEVFEFLYDQKIRGLAQVSVSGE
                     SGLKYSIDYIVSETKSQPEKLVNFTNNLDFNKITNEAYIYRDIKPNRPSRNKLEPIML
                     IIVNDVDHPINERAQTVAEHENLEILKWSNKSKIIETLTS"
     gene            complement(4367..5143)
                     /gene="seg"
                     /locus_tag="RFE25_002601"
     CDS             complement(4367..5143)
                     /gene="seg"
                     /locus_tag="RFE25_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031927817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type G"
                     /protein_id="HDU2817623.1"
                     /translation="MKKLSTVIIILILEIVFHNMNYVNAQPDPKLDELNKVSDYKNNK
                     GTMGNVMNLYTSPPVEGRGVINSRQFLSHDLIFPIEYKSYNEVKTELENTELANNYKD
                     KKVDIFGVPYFYTCIIPKSEPDINQNFGGCCMYGGLTFNSSENERDKLITVQVTIDNR
                     QSLGFTITTNKNMVTIQELDYKARHWLTKEKKLYEFDGSAFESGYIKFTEKNNTSFWF
                     DLFPKKELVPFVPYKFLNIYGDNKVVDSKSIKMEVFLNTH"
     gene            complement(5426..6181)
                     /gene="sen"
                     /locus_tag="RFE25_002602"
     CDS             complement(5426..6181)
                     /gene="sen"
                     /locus_tag="RFE25_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type N"
                     /protein_id="HDU2817624.1"
                     /translation="MRLFYIAAIIITLLCLINNNYVNAEVDKKDLKKKSDLDSSKLFN
                     LTSYYTDITWQLDESNKISTDQLLNNTIILKNIDISVLKTSSLKVEFNSSDLANQFKG
                     KNIDIYGLYFGNKCVGLTEEKTSCLYGGVTIHDGNQLDEEKVIGVNVFKDGVQQEGFV
                     IKTKKAKVTVQELDTKVRFKLENLYKIYNKDTGNIQKGCIFFHSHNHQDQSFYYDLYN
                     VKGSVGAEFFQFYSDNRTVSSSNYHIDVFLYKD"
     gene            complement(6220..6750)
                     /gene="seu"
                     /locus_tag="RFE25_002603"
                     /pseudo
     CDS             complement(6220..6750)
                     /gene="seu"
                     /locus_tag="RFE25_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031927818.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="staphylococcal enterotoxin type C1/U"
BASE COUNT         2641 a          939 c          849 g         2321 t
ORIGIN      
        1 tactaaattg atgatataca cttttggttg tgtatgcatc tcacctatct ttttttgctt
       61 ttttcaaata agaaagtatt aaaaattaat gcctatacaa cgttaaagga ggaacagaca
      121 tggctaaact tgatttaaat agtcttgacg atgagcacgt aaaattatta ataaatgaat
      181 taaaatatcc agaaactcat atcgatgtaa atgaataaaa aacaatagtt gctagtcgaa
      241 taaatgaaag gcaagaaata ataagtttta agttaggaat aaagtacttc ttaacaataa
      301 aaagggataa catagaaaaa gataggtttt caatttcaat cattttcaaa gatacctatc
      361 acaccctagt tagaatagat attaacggtg gtactcacga taatccagat ggaacaatcg
      421 ctccgaaaag tcatattcac atatataatg ataagtgtga taaaaaggat aggtttgctt
      481 atgaaattaa cttgaaagat ttccccgaca tctataactt gtataatgtg tatatgtcgt
      541 ttttagagta aaaaaatata aaagaccttg aataaaggag ggataatatg actacgtttg
      601 atgctaaaaa attaaaaaaa gaatatcttg attggtataa tcagatttta gagttttcta
      661 atttatcaaa caattcagta aaaatagata ccccttttaa agataattct ttagataatt
      721 taaaaatata cgctttatac gatcagtcca gagacatgat tacactgact gatgacggct
      781 atactatatt tggtttagaa aataacggtg tttctataaa taaatttaaa aaacgtaaaa
      841 agatttttga agagcacctt tcagcttacg gtattaaata taacgataaa actcacgaaa
      901 tttttgttca aactaacttt aaaaatttta ataaatcgaa acataattta ttacagtgcc
      961 ttatatttgt taatgatatg tacttacttt ctaatcctaa gtcacagaac atatttacag
     1021 aagatgttgc aaacaaattg gatgaacata acatttatta cggaagagat atacctatta
     1081 taggaagcag tggtgttgtt cataatttcg acttttttat tagcgctaag aaaaatcaaa
     1141 aagaaaaatt tatcaatgtt ttttctaacc ctaataattc tatgattatt aagtcgaaaa
     1201 taacggatgc tatgcaagca aaaaaaataa aaagacacag gcaaaatgag tttattttta
     1261 ttttaaatga ctcaaaaaaa gaaataaatg aacataataa aaatcttctt catgaaaact
     1321 atattagtac aatagattat agcgaattag atgaaaagat aggtttattg atttaatatt
     1381 tatagacgtg ataatatcaa tgtttatatt aaatgaaacg aatttgaaaa tttcgaaaca
     1441 gcttaagata gcaaattgaa tagtcttata gataatgcag aatcgtctac acatagttaa
     1501 acaaattatt tgagaataat tattgttaaa ctatgtggat aggcgatttt attttgacaa
     1561 gagtcagaag aacatatatt aaggatttca aattacaaat ggctaaactt tatgaaaatg
     1621 gtatgactag aatcgaaatt atacgcgaat acgatttaac actctcaatc ttctcgaact
     1681 gaataaatac tgggtcattc aatcattaag acaacttaat aagtgatgat atatgttcat
     1741 accattttgc aaatataacc agatactctc aacaaaatgt agagttcaaa attaaaaatg
     1801 tcaacattat agtaaactaa catagtcccc tgttcatatt cttcaatctt taaatcttat
     1861 cgaacaaata aaagcagata attttttaat ttgaacgttt tattttagaa caaaaaagag
     1921 caaggttaac gagtcagaaa atctttttct tgatacgtat atgacacttg ctcttttaag
     1981 aatctgaata tttcacgcta tttccattaa attagcggag aatgaatgat atctttatac
     2041 taataaattt aactttttaa cgtataaaat taatgcattg tactaaagtt tcaattattt
     2101 tataattgta tgaatgaatc gtatacactt aggtagtcaa atctaagaat ttagatattg
     2161 tttaatttta aaactatcga ttcacatata aataaaagga gataacagca tgaggagatt
     2221 actcagtcta ttactagcta gtacaatgat tttagtcgca tgtgggaatg ctaacaatga
     2281 aaataagaaa aaggaagacg aaaaaaaatc agaagtaaaa aaagaagcta cgaaaaataa
     2341 tgataaacca aagaacgaaa agaagaatca agatataaat aaaaacaata atgagcaagt
     2401 tcaaaatgtc aataataaac aaccagtctt aaataataat agtaatcata acaatcaaca
     2461 acaaagcaat aaaaataatt acacagttat agaaaacggg aatacagtta cagaaattta
     2521 taatggacaa tcacacacaa ctacaaataa ccctattaga gaagaatatg tagagggaga
     2581 aacagacccg atatataaaa gagagtataa gcatttttat acacctgaag aagctcaaag
     2641 agcacaagaa aatagcgacc aaattttaag agaaatgggt ctcgaaccag aaagatatga
     2701 ataaaatcaa actaaataat ttcgggtagc ccccctaccc ttattatttt tttgctaaga
     2761 agtaataatt atatttctaa tatgattagg ttcgatgtta atggtagtga tcatgcaaat
     2821 ccaccaaata atgaaagaat acctacgcca catatacaca tatatactga agaatataat
     2881 aatggtggta ttgcgatccc attaaaagat attgaagatt tagaattaac agatgaaatt
     2941 atagaatcat tagacttctt tatgaagtat actaatataa aacacgataa tgttataaaa
     3001 gaaccaagat tactgtaaaa gaaatggagg gatacttagt gaagactatc gaagaaagaa
     3061 tgaacgaata tttcaactgg ttaaagcaaa attatatctt caaagaatta gatagttcta
     3121 cagaaattac tactaccttt aagaaccatt tgaatgattt tattagaata tatgctgata
     3181 cactacctaa taatgaaatt tgtctatcag atgacggatt gacgattaat gaattagaaa
     3241 tgttgggtat tgatataaac acaaaaacga gaactaaact tatacagaat attttaaatc
     3301 aatttaattt aaaattagtt gataaagaaa ttacagcgga tgttaaaaat gagagttttg
     3361 ctcagtctaa acataattta attcaaggca tattgaaaat ttatgacctt actttaacta
     3421 ctaaatctaa cgttacaaac atattctatg aagaagtatt tgaattctta tatgaccaaa
     3481 aaataagagg tttagcacaa gtttctgttt ctggagaatc aggtttaaaa tattctattg
     3541 attatattgt ttctgaaaca aaatcacaac cagaaaaact agttaacttt acaaacaact
     3601 tagatttcaa caaaataact aatgaagctt atatttaccg tgatatcaaa ccaaacagac
     3661 catccagaaa caaattagaa cctatcatgt tgataattgt aaatgatgta gatcatccga
     3721 taaatgaaag agcacaaact gtagcagaac atgaaaacct tgagatatta aaatggtcta
     3781 ataaatcaaa aatcattgaa actttaacct cataaattag cagtagtccc ttatttatat
     3841 tctttaattt ccaaaccata tcgtgcaaat agaaaagcag ataacttttt tatttgcacg
     3901 ttttatttta gaacaagaaa gaacaaggtc aacgagtcag aaaaactttt tcttgatacg
     3961 tatttgacac ttgctctttt aagaaaacta acaattcatt gtatttccgt taaattaacg
     4021 gagaattcgg attacctaga tagatttacc tctagagtgt taaaaaattg tacattctta
     4081 aacaatcata aatgtacgtt attaaattat catttccact ggagaatcat gtcgactaaa
     4141 agattataaa agtaaaaata catttaaaag cacgtcattt tcaaaccgcc ataaaacagc
     4201 atttttaaac cgctattgac ataaaatata tttagaataa atcatttaga aaaattaaat
     4261 aatttaaccg gcaataaact aactatttac atgaatctat aaaacactta gaacaaaagt
     4321 tcgaaaaacg cactttatga ttgtatagtg atatcaaata tacttatcag tgagtattaa
     4381 gaaatacttc cattttaata ctcttagaat caacaacttt attatctccg taaatattta
     4441 aaaacttata tggaacaaaa ggtactagtt cttttttagg aaataagtca aaccaaaaac
     4501 ttgtattgtt cttttcagta aattttatat atccagattc aaatgcagaa ccatcaaact
     4561 cgtatagctt tttttcttta gtgagccagt gtcttgcttt gtaatctagt tcctgaatag
     4621 taaccatatt cttatttgta gttattgtaa atccaagtga ttgtctattg tcgattgtta
     4681 cctgtacagt aattaattta tctctttcat tttctgaact attaaatgta agaccaccat
     4741 acatacaaca acctccaaaa ttttggttta tatccggttc agatttaggt attatacatg
     4801 tataaaaata tggaacgcca aaaatgtcta cttttttatc tttataattg ttagctaatt
     4861 ctgtattttc taattcagtt ttaacctcat tataactctt atactcaatt ggaaaaatta
     4921 aatcatgaga taaaaactgt ctagaattaa taactcctct tccttcaaca ggtggagacg
     4981 tataaagatt cattacatta cccatagttc ccttattatt tttataatca cttactttat
     5041 ttagttcgtc taatttagga tcgggttgag cattcacata attcatatta tgaaaaacta
     5101 tttctagaat caaaataata attacagtag ataatttctt cataaaacct cctctaactt
     5161 attcagtcta tttgacaatg aaccttatta taaattcacg cttatagata gttcaggttg
     5221 tagtgtgtcg atagcattgt tttaaaacta aaaattcact agcagaataa attaaaattc
     5281 tatttatcat tattactaat tacaacaaat aattttgaat ccgtattcaa gataatatat
     5341 aaatttcaaa ttttactaca attcaaatca ttttcctctc ataaaatggt ttaatttcat
     5401 gattcagttg ataatcatca atcacttaat ctttatataa aaatacatca atatgataat
     5461 tagatgagct aactgttcta ttatcactat aaaattgaaa aaactctgct cccactgaac
     5521 cttttacgtt atataaatca taataaaatg attgatcttg atgattatga gaatgaaaga
     5581 aaatgcatcc tttttgtatg ttaccggtat ctttattgta tattttatat aaattttcta
     5641 atttaaatcg aactttagtg tctaattctt gtactgttac tttagccttt ttggttttta
     5701 taacaaaacc ttcttgttgg acaccatctt taaatacatt aacgcctata actttctctt
     5761 catctaattg atttccatca tgtatcgtaa ctcctccgta taagcatgat gttttttctt
     5821 cagttaagcc tacacattta tttccaaaat acagtccata aatatctata ttttttcctt
     5881 taaattgatt tgctaaatct gatgagttaa actcaacttt caaactagaa gttttaagta
     5941 cggatatatc aatatttttt aatattatag tattattcag tagttgatct gtactaattt
     6001 tatttgactc gtctaattgc cacgttatat cagtataata gcttgttaaa ttaaataact
     6061 tactactatc tagatcagat tttttcttta aatctttttt gtctacttca gcattaacat
     6121 aattattatt aataagacat aataaagtta ttataattgc agctatgtag aacaatctca
     6181 taagcttttt aatatttttt ataatattct ctccctcaat tattttttgg ttaaatgaac
     6241 ttctacatta atagatttac tctcaactgt tttattatca ttataaatta gtaaatattt
     6301 agtcggataa aattttttac cagattcagg catcaaatca taccaaaaag aatgaccact
     6361 tccttcgata aactttatat agccagtctc ataaggcgaa ctgttaaatt catataaatt
     6421 tttatgctta agtaaatagt ttctaacttt ataatctatt tcttgtgctg ttatgttttt
     6481 cttattagta ggtatatcaa aagataatga atttctctcg ttttcataaa ctttaattaa
     6541 gatattatga gagttatcag ttgaattatt tttatctatt tgatttccat catgctcggt
     6601 cacaccgcca tacatacacg tttttttcaa ttaatctacc atcatttaat tccatattat
     6661 ccaatgaaaa atagcattga ttataatagt ttgtcccaaa caaatctacg tttttatttt
     6721 tatatttatc cgaaaggctt ttattattaa
//
LOCUS       DAPDIM010000101         6685 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000101 DAPDIM010000000
VERSION     DAPDIM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6685
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.102"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            90..884
                     /locus_tag="RFE25_002604"
     CDS             90..884
                     /locus_tag="RFE25_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2817625.1"
                     /translation="MIHSKKLTLGICLVLLIILIGGCIIMTKINSRNAQIKDTFNQTL
                     NVYPTKNLDDFYDKEGFRDQEFDKRDKGTWIINSGMYIQLKGGALKSRAMVLYINRNT
                     RTAKGYFLISETTEDKKGYVHNKDKKYPVKMERNRIIPTKPITDEKLKKEIENFKFFV
                     QYGNFKDFKDYKDGDISYNPNVPSYSAKYQLNNDDYNVQQLRKRYDISTKRAPELKLR
                     GSGDLKGSSVGSKELEFNFVRNKEENVYFSDGINFKPTEEMNHEQN"
     gene            871..2196
                     /locus_tag="RFE25_002605"
     CDS             871..2196
                     /locus_tag="RFE25_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817626.1"
                     /translation="MNKTKYQINSDNIKSNSEETSAISSISYEIENANNNDLNNASIQ
                     TQIEILKSQNSFPKNLSYLKSYTDPKTGTTTSAFLNKDTGKVTLGMTGTNVHKDAILK
                     QTFGVPSYQGYIDASETLKDIGADVNIGLHSVTDKDPHYKNTQDFIKNIKKDYDIDII
                     TGHSLGGRDAMILGMSNDIKHIVVYNPAPLAIKDVSGLYADQEELKKLIEKYDGHIVR
                     FVSDEDELDAGVRNHLYETAGEKIVLKNGEGHAMSGILMSRTQAIILAELNKVKGYQD
                     ENNKALKSVRKQTRHRLHKVETLRANWIQTTGGSLSSSQQQLLEALTALTIAEGLNQL
                     VNEESQHLKKMYHAMAHKFGDNWKKAQEVGNEIGEKLTSEEVIDELRKGGAYESKLET
                     DPKRKIDDKIKKLNDVYKNCNGYIAKIKQSIEAIVSNDQMLASQIDGMM"
     gene            2196..2522
                     /locus_tag="RFE25_002606"
     CDS             2196..2522
                     /locus_tag="RFE25_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817627.1"
                     /translation="MFTTYKNINELENAYDEERKQLNDAFNQIDELRHQTRKKCEQMY
                     DHFLYLKHKMNYSEDAMIRMTRIIESFDRETNQRIRHHEMKLEDYKDELRREYLKQSD
                     RIEGDE"
     gene            2525..2812
                     /locus_tag="RFE25_002607"
     CDS             2525..2812
                     /locus_tag="RFE25_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817628.1"
                     /translation="MGLDFSGLPDLAVLEQMKEKEQISEVIAPEHVRMHHDHQNKLKS
                     DEKILLDQMVSHFKNFEDDFKNAAQGAWVKNATDELKDISNDLEKIQDIKV"
     gene            3129..3236
                     /locus_tag="RFE25_002608"
                     /pseudo
     CDS             3129..3236
                     /locus_tag="RFE25_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649608.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Csa1 family protein"
     gene            3348..4142
                     /locus_tag="RFE25_002609"
     CDS             3348..4142
                     /locus_tag="RFE25_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2817629.1"
                     /translation="MIHSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKDTFNQTL
                     KLYPTKNLDDFYDKEGFRDQEFKKGDKGTWIVNSEMVIEPKGKDMETRGMVLYINRNT
                     RTTKGYYFISEMTDDSNGRPKDDEKRYPVKMEHNKIIPTKPLPNDKLRKEIENFKFFV
                     QYGDFKDINDYKDGDISYNPNVPSYSAKYQLKNDDYNVKQLRKRYNIPTNKAPKLLIK
                     GDGDLKGSSVGSKNLEFTFVENKEENIYFTDSVQYTSSEDTSYESN"
     gene            complement(4146..4268)
                     /locus_tag="RFE25_002610"
     CDS             complement(4146..4268)
                     /locus_tag="RFE25_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817630.1"
                     /translation="MSYIIKFTFKFFEMATYISQLTLDIELVSSELLVILPGFI"
     gene            4703..4894
                     /locus_tag="RFE25_002611"
     CDS             4703..4894
                     /locus_tag="RFE25_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817631.1"
                     /translation="MRKEIEALIFSDVSSYDIYVNTGVNQGLIGDIKDGYLTIDSMPY
                     IDAERLYHFAMERKSLVTN"
     gene            complement(5033..5218)
                     /locus_tag="RFE25_002612"
     CDS             complement(5033..5218)
                     /locus_tag="RFE25_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817632.1"
                     /translation="MLYILITALNVILNKLKMKDSNIISFIYSRHDRILYVNLVGNRF
                     KNNISMTKATSNIGRGF"
     gene            complement(5154..5435)
                     /locus_tag="RFE25_002613"
     CDS             complement(5154..5435)
                     /locus_tag="RFE25_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDU2817633.1"
                     /translation="MTYHERVLALRAESKRTAFDFRFEDLFSKEEWLSMSLAERQKAE
                     KAFRHEVKNMDDVRMPFSSVHDAQVKLYNVVYSYNGIKRNFKQVENEGF"
     gene            5724..6419
                     /locus_tag="RFE25_002614"
     CDS             5724..6419
                     /locus_tag="RFE25_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDU2817634.1"
                     /translation="MTVLTDKIAVVTGAGSGIGEAIATLLHEEGAKVVLAGRNKDKLQ
                     NVANQLAQDSVKVVPTDVTNKEEVDELMKIAQQTFGGLDIVINSAGQMLSSKITDYQV
                     DEWDSMIDVNIKGTLYTAQAALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAV
                     HTITQGLEKELAKTGVKVTSISPGMVDTAITAAYNPSDRKKLDPQDIAEAVLYALTQP
                     KHVNVNEITVRPV"
BASE COUNT         2613 a          904 c         1187 g         1981 t
ORIGIN      
        1 aattaaattc atttgttcaa aacaattttt cgctttagtt gtaaatatta aaaactgagt
       61 cagaattata aatataaggt ggagaaatga tgattcattc aaaaaaatta acgctcggta
      121 tatgtttggt attactcatt atattgattg gaggttgtat cattatgaca aaaataaata
      181 gtcgaaatgc ccaaattaaa gacacattta atcaaacatt aaatgtgtat ccaaccaaga
      241 atcttgatga tttttacgat aaggaaggct ttcgagatca agaatttgat aaaagagata
      301 aagggacttg gattattaat tctggaatgt acatccaatt aaaaggagga gccttaaaat
      361 ccagagcgat ggtactttac atcaatcgta acactagaac agctaaggga tattttttaa
      421 taagtgagac aacagaagac aaaaaaggat acgttcataa taaagataaa aaataccctg
      481 tcaagatgga acgtaatcga ataattccaa cgaagcccat aacggacgag aagttaaaaa
      541 aagagattga aaactttaag ttctttgtac aatatgggaa ttttaaagat tttaaagatt
      601 ataaagatgg ggatatttca tacaatccta acgtaccaag ttattccgca aagtatcaat
      661 tgaataatga tgattataat gtccaacaat taagaaaacg atatgatata tcaaccaaaa
      721 gggcacctga attaaaattg agaggatctg gcgatttaaa aggctcatcc gtaggttcta
      781 aagaactaga atttaacttt gtaagaaata aagaggaaaa tgtgtatttt tctgatggta
      841 ttaatttcaa acctactgag gaaatgaatc atgaacaaaa ctaaatatca aataaattct
      901 gacaatataa agagtaactc tgaagaaaca agcgcaatat ctagtataag ttatgaaata
      961 gaaaacgcaa ataataacga tttaaataat gcaagtattc aaacgcaaat agaaatatta
     1021 aaatcacaaa atagtttccc taaaaatctt tcatatctta aaagttatac ggaccccaaa
     1081 acaggtacga ctacaagcgc ctttttaaat aaagacactg gcaaagttac tttaggtatg
     1141 acaggtacta atgtacacaa agacgcaata ttaaaacaaa catttggtgt tccttcttat
     1201 caaggatata tagatgcgag tgaaacgcta aaggatattg gggccgatgt caatattggc
     1261 cttcattccg tcacagataa agatccacat tataaaaata cccaagactt tatcaaaaat
     1321 atcaaaaaag actatgatat tgatattatt accggacatt cgctgggcgg tagagatgcg
     1381 atgattttag gtatgagtaa tgatattaaa catatcgttg tgtataatcc agctccatta
     1441 gcgatcaaag atgtgagcgg cctttatgcc gatcaagaag aacttaaaaa attgattgaa
     1501 aagtacgatg gtcacattgt aagatttgtg tctgatgaag acgaattaga tgcaggtgtc
     1561 cgcaatcatt tatatgaaac tgctggagaa aaaatagtac ttaaaaatgg agaaggccat
     1621 gcaatgagtg gtattttaat gagcagaaca caggctataa tcttagctga attaaacaaa
     1681 gttaaaggct accaagacga aaataataaa gcattaaaat ccgttcgtaa acaaacgagg
     1741 catagattac ataaagtaga gacgttaaga gcgaattgga ttcaaacaac gggtggatca
     1801 ctctcttcct cccaacaaca attattagaa gctttaacag cactaaccat tgccgaaggc
     1861 ttaaatcaat tagtgaatga agaaagccaa catttgaaaa aaatgtatca cgcgatggca
     1921 cataaatttg gagacaactg gaaaaaagcg caagaagttg gaaatgaaat tggtgaaaaa
     1981 ttaacctctg aagaggttat agatgaatta agaaaaggtg gcgcgtatga aagtaaactt
     2041 gaaacagatc ccaaaagaaa aattgatgat aagataaaga aattaaatga tgtttataaa
     2101 aattgtaatg gctatatcgc aaaaattaaa cagagtatcg aagcaattgt ttctaatgac
     2161 caaatgttag cgagccagat tgatgggatg atgtaatgtt tactacgtat aaaaatatta
     2221 atgaacttga aaatgcctat gatgaagaaa gaaaacaatt gaatgatgca ttcaatcaaa
     2281 ttgatgaatt aagacatcaa acacgcaaga aatgtgaaca aatgtatgat catttcttat
     2341 atctcaaaca taaaatgaat tatagtgaag acgctatgat caggatgaca cgtattatag
     2401 aatctttcga tagagaaacg aatcaacgta tccgacatca cgaaatgaaa ttagaagatt
     2461 ataaagatga gttaagaaga gaatatctaa aacaatctga cagaattgaa ggagatgaat
     2521 aagcgtggga cttgatttta gtggtttacc agatttagca gtattggaac aaatgaagga
     2581 aaaagaacag attagtgagg ttattgcgcc tgaacatgtt cgtatgcatc atgatcatca
     2641 aaataagctg aaaagtgatg agaaaatatt acttgaccaa atggtaagtc atttcaaaaa
     2701 ctttgaagat gattttaaaa atgcggcaca aggggcttgg gtgaaaaatg ccacagacga
     2761 attaaaagat attagtaatg atttagaaaa aattcaagat attaaagtat aaaaaggtat
     2821 taagaaacac aataagtata taatccattt aataataaat aaattatata gttcataatc
     2881 tcgactataa gtggctatta gccattattt ttcgggatct atgtcaaatc ggactaatga
     2941 attcaataat ggaagttaag caaccaatct ttgtttaact tcttttttat tttttggaaa
     3001 ataaagtttt gaacataata aaatttgatt atgttttaac gaattttgat gtttcttgaa
     3061 ctatatatca tctagtcgtc atttacaatt ggtaaatatg acttcaaact gtatgaaggt
     3121 gatggcgatt aaaaggctca tccgtaggtt ctaaagaact agaatttaac tttataagaa
     3181 ataaagaaga aaatgtgtat ttttctgata gtattaattt caaacctact gaatagggtt
     3241 aatagaagtt tgaaataaaa atttcataaa gtgttcaaaa taatttttcg ctttagttgt
     3301 ataaattaaa gattgagtca atattaaaaa tataaggtgg agaaatgatg attcattcaa
     3361 agaaattaac gctcggtata tgcttggtat tactcattat attgattgta ggttatgtca
     3421 ttatgacaaa aacaaatggt cgaaacgccc aaattaaaga cacatttaat caaacattaa
     3481 aattatatcc aaccaaaaat ctcgatgatt tttacgataa agaaggcttt cgagatcaag
     3541 aatttaaaaa gggtgataaa ggtacttgga tagttaattc tgaaatggta atcgagccaa
     3601 aaggtaagga tatggaaacg agaggaatgg tgctctatat caatcgcaat actagaacca
     3661 caaaagggta ttattttata agtgaaatga cagatgacag taacggcaga ccaaaggatg
     3721 atgaaaaaag gtatccggta aaaatggaac ataataaaat cataccaacg aagccactac
     3781 cgaatgacaa gttaagaaaa gaaatcgaaa actttaaatt ctttgtacaa tacggtgact
     3841 ttaaagatat taatgattat aaagatggtg acatttcata taatcctaat gttccaagtt
     3901 attccgcaaa atatcaattg aaaaacgatg actacaatgt gaagcaactt cgaaaaagat
     3961 ataatattcc aaccaacaaa gctccgaaat tattaataaa aggtgatggt gatttaaaag
     4021 gctcatctgt agggtcaaaa aatctagaat ttacctttgt agaaaataaa gaagaaaaca
     4081 tttattttac agattctgta caatatactt caagtgagga tacaagttat gagtcaaact
     4141 gaatatcaaa taaaacctgg taatataaca agtaactctg aagaaacaag ttcgatatct
     4201 aaagtgagct gtgaaatata ggtagccatt tcaaaaaatt taaaggtgaa tttgataatg
     4261 tagctcaagg agattgggtt aaaaaggcga agaatgaact ggatgatatt agtaagaaat
     4321 taaaaaatat tcaaagaacg gaagtttaat attctagccg attcctgaaa ctaagacagc
     4381 atgcgttcat tcatgccatt attaatataa gcaccgcaac aaaaaagctt ctaatgtgat
     4441 acaggaacct catattccgt atcatgttag aagcttttaa tgtctaaaga acatctacat
     4501 tttatcatat tttctgactt attaaacttt tatataatta actatttctt aattttccaa
     4561 aatagtgata aatttgtgaa atacatcaca aatctcttta tttatttgga aattcatgta
     4621 atattagact tgtaagaagt taataaatag agagagacga gagagtttat ataaataata
     4681 tataaacatt ggagtgatga ttatgagaaa agagattgaa gcgcttattt tctcagacgt
     4741 aagtagctat gatatttacg tgaacactgg tgtaaatcaa ggattaattg gtgacatcaa
     4801 agatggttac ctaactattg attctatgcc ttacattgat gctgagcgtt tgtatcactt
     4861 tgctatggaa cgtaaatcgt tagtcactaa ctagttctta ttgccaatga ttactacccc
     4921 tagtcggcgg caattgaagt gtgattgatg taacttgccc tcgttggtga gcaattgagg
     4981 gcagatccct ttaattaagt aaaccctaac tccccacaaa tctggaacga tactaaaagc
     5041 cacgtcctat attggatgtg gctttagtca tacttatatt atttttaaaa cgattaccta
     5101 caagatttac atataaaatt ctatcatgtc tgctatatat aaacgaaatg atattagaat
     5161 ccttcatttt caacttgttt aaaattacgt ttaatgccgt tataagaata tacaacatta
     5221 tataatttta cttgggcgtc atggacactt gagaagggca ttcttacatc gtccatattt
     5281 ttaacttcgt gtcgaaatgc tttttcagct ttttgtcttt ctgcaagaga catacttagc
     5341 cattcttctt tgctaaataa atcttcgaat cgaaaatcaa atgcggttct tttactttct
     5401 gctcttaatg ctaaaacacg ctcatgatat gtcacgttta attcctccct ctaatcattc
     5461 aatcgaatga taaatcacag tattaacttt agtactaata taatgttttt acaataaaga
     5521 agtgacgatt tttcaacatt tttaaaaata aaaaatataa gcaacgatta attgtatatt
     5581 tcgaatggct tgtaatgtaa tttatctatg aaaatgaagc gagttattat gaccgttata
     5641 tgaattgtga tacgcttttt aaaagtaata tgtatttatg atttaccctg aaaaaataaa
     5701 aagaatcaaa ggagtcgatc attatgacag tattaacaga taaaatagca gtagttacag
     5761 gtgcaggtag tggtattgga gaagcaattg caacattact acatgaagaa ggggcgaaag
     5821 ttgtcttagc cggtagaaat aaagataaac tacaaaatgt ggcgaatcaa ttagctcaag
     5881 atagtgtgaa ggtagtgcca acagatgtaa cgaataaaga agaagtcgat gaattgatga
     5941 aaattgcaca acaaacattc ggtggtttgg atattgttat caatagtgcg ggacaaatgt
     6001 tatcgtctaa gattactgat tatcaagtag atgagtggga tagtatgatt gatgtgaata
     6061 tcaaaggcac tttatatacg gcacaggctg cattaccaac tatgttagaa caatcaagtg
     6121 gacatcttat taacattgca tctatttctg gctttgaagt aacgaaaagt agtacgattt
     6181 atagtgcgac gaaagcagca gttcacacta ttactcaagg attagaaaaa gagttggcaa
     6241 agacaggcgt taaagtaaca agcatttctc caggaatggt agatacagca ataacagccg
     6301 catataatcc aagtgatcgt aaaaagcttg atccacaaga tattgcagaa gcggtattgt
     6361 atgcattaac acaaccaaag catgttaacg tgaatgaaat tacagtgcgt cctgtataaa
     6421 aaggtgtttg aggtgtggga gatagacatt taatgtaata gctatcgatt ttgttaatgt
     6481 tagtaaggca ataatgacat gagggcataa taggcaatta ttccttgtac aattctcagt
     6541 aattggtgat tttaacaatc aagttaatga aggcgacgat gttagtgtta tggtttataa
     6601 tctataatgt tcgtaattac agattacaaa aaaatttcat tttccaccac attttaggag
     6661 ttactttaat gaacaaaaaa catgt
//
LOCUS       DAPDIM010000102         6650 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000102 DAPDIM010000000
VERSION     DAPDIM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6650
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.103"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(161..682)
                     /locus_tag="RFE25_002615"
     CDS             complement(161..682)
                     /locus_tag="RFE25_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwhD family protein"
                     /protein_id="HDU2817635.1"
                     /translation="MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFID
                     VANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAG
                     LTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGM
                     WKLSSDALHQAFN"
     gene            complement(710..2005)
                     /locus_tag="RFE25_002616"
     CDS             complement(710..2005)
                     /locus_tag="RFE25_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDU2817636.1"
                     /translation="MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLR
                     RIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALL
                     HDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVSPEFPREVAEVINKTHH
                     NKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMH
                     AVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFE
                     ETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISE
                     LQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIH
                     SITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN"
     gene            complement(2045..2521)
                     /locus_tag="RFE25_002617"
     CDS             complement(2045..2521)
                     /locus_tag="RFE25_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2817637.1"
                     /translation="MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASY
                     NEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNE
                     GLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYQPEMYGEKLDLALMYKAF"
     gene            complement(2689..3225)
                     /locus_tag="RFE25_002618"
     CDS             complement(2689..3225)
                     /locus_tag="RFE25_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDU2817638.1"
                     /translation="MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDV
                     RHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRY
                     PNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDI
                     MKDNYALARATEWNSILQ"
     gene            complement(3671..4609)
                     /locus_tag="RFE25_002619"
     CDS             complement(3671..4609)
                     /locus_tag="RFE25_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDU2817639.1"
                     /translation="MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQ
                     AINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQP
                     EYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFT
                     LDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHLITFIPYFPLASGILAGKYDE
                     NTKFSDHRTTRRDFIPGVFEENVRRVKALESLAAAHQTSIANIVLAFYLTRPAIDVII
                     PGAKRAEQVIENIKAADIVLSDDEIQYIDELFPIED"
     gene            complement(5057..5689)
                     /locus_tag="RFE25_002620"
     CDS             complement(5057..5689)
                     /locus_tag="RFE25_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDU2817640.1"
                     /translation="MVCEVIAIYKNPKYRIIKYNDEYLMVNIINNWLVLFIPLLNWLT
                     PKRYIKISQEELESLNTFKPAKNNAFWPALGSSVLFSVTFRKYMPLFNVRLEKTIVIA
                     IFFVVFLGILFFYLNLNRRLALSVFTMNKEKSQKMILLPNLKHFFFIIFAYLYFGGFS
                     FFTLYALITIDVQNIIIFICWGAVTMFFFFINIVPIGIKKAHVILLKKAE"
     gene            complement(5829..6449)
                     /locus_tag="RFE25_002621"
     CDS             complement(5829..6449)
                     /locus_tag="RFE25_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000882081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDU2817641.1"
                     /translation="MLCESKIINKNPKYRIIKYNDEYLMIDIISTWISLFFPFINWFI
                     PKRYVKISREEFENLNIVKPAKKNVFWPVASISTLFAVTLRKYTLLLDTQLDKKLVIA
                     ICCTTFIGILIFYVRLIKKSSLNIYNTKNKRSKIILIPTLKNFCFTLFGYVFLIFWTV
                     IFSYALLSMSYQNIIVYFAWITAIIGFFLVNIALIIDKNIHVILKN"
     gene            complement(6496..>6650)
                     /locus_tag="RFE25_002622"
     CDS             complement(6496..>6650)
                     /locus_tag="RFE25_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDU2817642.1"
                     /translation="SYGAFYLLVFENVQNLILYISWLFMTMLFMLMNMHSIIDKKVHI
                     FLKSNK"
BASE COUNT         2220 a         1173 c          867 g         2390 t
ORIGIN      
        1 ttattcaaat tttttattaa ctacagatta atttaatttc aaaaaaatta aaaaaactcc
       61 caaccaatct aagactttat tttcacctca agatttacgt cgtcattgag aaatgaatca
      121 tatctttata gattaattgg gaaattttag tttctaatat ttaattaaat gcttgatgta
      181 aagcatcaga agaaagcttc cacatacctt catcatggtt cattaaaaag tcttttaaaa
      241 tagctttatt ctcgtcacca atttgatcaa tgataatatg atgtttcatt gatttatcca
      301 tcatattaac atgttcaggc atacttttat aaccacgacg aattgcttta ttcactaata
      361 aatagcacgc tgttaaacca gcgtaatatg gtccttgttc attacgttct gttgttaccc
      421 aacacaacca atattcttta gcttcatcgc cttcaacagc agctttatca gtaatccatt
      481 tcacaccttt ttcaactttg gcacgagcat gcatgcctcc aatatcaata aatgcttctt
      541 tgttagcaac atcgataaaa actggtgcaa tattgtctaa gctaattgaa ccaatatttg
      601 tacctttatg accatctaga gggtcatttt ttatgatatt aaaattaaag ccttttttct
      661 cagacaatga tataacctcc atatttaacg ataacaattt tagccctgtt taattaagct
      721 cattaatcaa attttcaata gcttctctaa ttgtcttatc tttaatcttt gcaaccattt
      781 ctctaggata atataattta tagtcttggc gattaatgcc tgtaatacta tgaatgacta
      841 atgattgatt gcttatttct ctaatcgtac catcttgtct taataaatga atcggtttgc
      901 gatttgaccc cggtcgatca tagtcatatg gcaaatccga aaatgcttca ctcacaaaat
      961 aataatctgg attaatacca cctgcttcaa acagttcttg cagttctgat attgtaataa
     1021 ttgagccatc aaatggaata tatttaaata agtctcgatt aataaatcga cttgctaaat
     1081 cacttaaaat ggcatcatct tcttttgtcc atttttccaa ataatacgta actaccgctt
     1141 catcgagttc aacatattgt tcaatcgtaa ctgtctcttc aaaaaatgga ataaaatcat
     1201 gtggatgcaa cttaaattca tagccttcat tataaagctg ttttgcgcgt ttcaaacaat
     1261 tattaagcag cacttctcca ccacgactaa ctgggtggaa gtaaatttgc caatacattt
     1321 gataacgact cataataaag ttttcaactg catgcatacc actttctttg attagtactt
     1381 catctttaga aggtcgcatt aatcttaaaa tacgctccat atcaaaagca ccatatgata
     1441 cacctgtgaa atacgcatca cgttgtaaat aatccattct atccgcatcg atttgtgacg
     1501 aaatcatcga aatgaccaat ttattatgat gcgttttatt aattacttcc gcaacttctc
     1561 ttggaaactc aggcgacact ttacgtaata cagcattcac ctcagtatct ccagtaataa
     1621 tcgcttgtgt gtatgcttca tggtctgtat taaatatttt ttcaaaacta tgtgaaaatg
     1681 gaccatgtcc taaatcatgt aataatgcag cacataatgc caacggtcta tctttattgt
     1741 cccatgcatc atgaccaata aatgactcat caattaatcg tctaactatt tcatacacac
     1801 ctaaagaatg tccaaagcga ctatgttctg ctgtgtgaaa agataggtac agtgttccta
     1861 gttgtctaat tcgacgtaac ctttggaatt ccttagtttt aattaaatcc catatcaatt
     1921 gatcttcaac atgaatatat cgatgtatcg gatctttaaa aactttttct tctactaatt
     1981 ttaaatctac atatgcgtta gtcattattc ccctcctttt cgtttaatat aatatttaat
     2041 ttacttaaaa tgctttgtac ataagtgcta agtctaactt ttcgccatac atttctggct
     2101 gataagagcg taagattgta aaaccttgct ctttatagta agctactgct tcttcatttt
     2161 tattatctac ttctaagtaa acaccttcaa atttatcttc aaaacgtgat aatccttcat
     2221 ttaacaatgc tgtaccataa cctgtatgtt gcgattctgg tttaacataa tgagctgata
     2281 aatataattc ttcaccgtaa ataaagttag caaagccaac gatgtcatta ccttcttcaa
     2341 cgactaagaa taattgttct tgaagtcttt tctttaaatg atgttcatta tatgaagctt
     2401 ctaacaagtg attaactgtt gtcgcagcgt atatatttaa gtatgtatta aaccaagctt
     2461 tagttgcgac atctctaatt tgaacaacat ctttttcagt tgcttgtctt accttgaaca
     2521 tgactttctc cccttattaa caagttttaa taacggcatt ataccacaac ttgctcaata
     2581 cttaataaac aatgattgtc tattcaattt atatatttat attttccgtt aaaattaaaa
     2641 ataaaaataa cgaagcaaaa aatcacttcg tttagtatga ggtatgtctt attgcaatat
     2701 actattccac tcagttgcac gtgctaaggc atagttgtct ttcatgatgt caccaggctt
     2761 ttcagcagtt ccaataatat aaccatttaa agtggcacct aaaaagtcta aactatattt
     2821 catttgcgta attgctggct tcgcttttat ttttggacaa tctccaccaa ctaaaataac
     2881 tctaaaatcc ttttcggcca tttgtgcctt aaaattagga tatcgtttat cttgtaatgt
     2941 ttctgaccaa tgttcgataa atgctttcaa tggtgctgaa atgctatacc aatacactgg
     3001 tgatgcaaaa ataattgtat cactagccaa tattttatct agaatcggca aatagtcatc
     3061 gtcatatgaa gtaatagtct ctgctgtatg tctcacgtca cgtatcggtt taaactgatg
     3121 ttgtgtcacg tcaatccatt gatactctaa atcttgcaaa gcgaattttg ttaattgtgc
     3181 agtattaccg tttggtctac tcccaccaaa caaaacagta atcattttag cctaacctca
     3241 cttttgatta ataaatatct gtgtttttcg ttacctaatt atactatcat aagctttgcc
     3301 taccgaatag taaaacgctt acaactttta tataaatttg acgaaatttc gtcatgcctt
     3361 atataacgtc gtttgtgatg ggagtgggac agaaatgata ttttcgaaaa atttatttcg
     3421 tcgtcccacc ccaacttgca cattattgta agctgacttt tcgtcagctt ctgtgttggg
     3481 gcccacaccc caacttgcat tgcctgtaga atttcttttc gaaattctct gtgttggggc
     3541 ccctgactag gattgaaaaa agcttgttac aagcgcattt tcgttcagtc aactactgcc
     3601 aatataactt cgtagagcat agaacattga tttatgtccc agcctgatat caccattaaa
     3661 tacaattcat ttagtcttca attggaaaca attcatcgat atattgaatc tcatcatctg
     3721 ataaaacgat atctgcagct ttaatatttt caatgacttg ttctgcacgt tttgcaccag
     3781 gaataatcac atcgatagct ggtctcgtta aataaaatgc taatacaatg ttcgcaattg
     3841 aagtttgatg tgctgcagct aggctttcca aagcttttac gcgacgcaca ttctcttcaa
     3901 aaacaccagg tataaaatca cgacgtgtag tacgatggtc actaaattta gtgttctcat
     3961 catattttcc agctaaaata ccggatgcta atgggaaata aggaataaat gtgattaggt
     4021 gatcaacaca atattgcaat actgcctcat tttcgcggtg caataaatta tattctaact
     4081 gtacaacatc aacgtaacca tctttatttg cttctttaag ttgatctaat gtgaaatttg
     4141 atacaccaat ggctttaatc ttcccttgtt ccttaagctc ttgtaatgct gcaactgctt
     4201 gatctttcgg agtgttgtca tcaggaaaat gaatataata taaatcgata taatcagttt
     4261 gtagacgttt caaactattc tcaacttgtt gttttaaata ttccggttga ttgttctgat
     4321 gtacttcttg attttcatca aattcatgag accctttcgt agcaatttta atttgctctc
     4381 gcggatattc cttaacaact tctccaacca attcttctga tcgttctggc ccataaatat
     4441 atgccgtatc taataaatta ataccatgat taatggcttg acgaacaaca tcttttcctt
     4501 gttcttcatc taagttcgga tataaattat gcccacctac tgcgttcgtc ccaagtgcga
     4561 ttggaaacac ttcaacatca gatttaccta agtttacaaa ttgcttcatt agacccagct
     4621 ccttatcttt ataacttttc cactatcaca ctatcatgat ttaatacaac ttccaaatgt
     4681 tagaattagg gtttgaatta aggcggtgta ttagaaaaat gttatgtaga actcagttaa
     4741 aataagtatt gcttaagttg atatgcatat agcgcgattg ctcgttgacc tttaaattac
     4801 atgtactttt gaatcagaaa ttgaaaaaca tttaagaacg acaatattaa agccattgca
     4861 aatttaatta gaaatactat aatgttttga tttgcataac aaagaaatta aaactgttaa
     4921 tattaacatg ggatatccat tataaaatat tcatctttgt agttgataat tctatatttc
     4981 ggatttttat tcattctatc tatgagtcaa atttttatat taaatttaat aattttagat
     5041 ttaaaaaact catttattat tcagcttttt taagaagtat tacatgagct tttttaatgc
     5101 caatgggaac aatgtttata aaaaagaaaa acatagttac tgcaccccaa cagataaata
     5161 taattatatt ttgaacatct atagttatca gggcatataa agtgaaaaat gaaaaaccac
     5221 cgaaatataa atatgcaaat attataaaga aaaaatgttt taaattaggt agtaatatca
     5281 ttttctgact tttttcttta ttcatagtaa aaacacttaa tgctagccta cgatttaaat
     5341 ttaggtagaa aaataaaata ccaagaaata caacaaaaaa tatggctatt actattgttt
     5401 tttccaatct aacattaaat aaaggcatat actttctaaa agtcacacta aataaaactg
     5461 aactacctaa tgctggccaa aatgcattgt ttttagcagg tttgaaagta tttaaacttt
     5521 ctaattcttc ttgactgatc ttgatgtatc tttttggtgt caaccaatta agcaatggaa
     5581 tgaataaaac taaccaatta tttattatat tcaccatcaa atattcatca ttatatttaa
     5641 taattctata tttgggattt ttgtatatag ctattacctc gcaaaccaat gtctccacat
     5701 ccctttaatt ttatgtgtaa tacatttttc gatacttcaa aagacattaa aatattatca
     5761 acttactatc attaaaaatt ttattcattg ttatttgcat atctttaatc tgaatttatt
     5821 accaccattt aatttttaag tatgacatga atgtttttat ctataattaa agctatattc
     5881 actagaaaaa aacctattat tgctgtaatc caagcaaaat atactattat gttttgataa
     5941 ctcattgata atagagcata tgagaaaatc actgtccaaa aaattaaaaa aacatatccg
     6001 aacaatgtga aacaaaaatt ttttagtgtt ggtattaaga tgattttcga ccttttattt
     6061 ttagtattat aaatatttaa agatgatttt ttaattaggc gtacataaaa tattaaaatc
     6121 cctataaatg tggtgcaaca tatggcaata actaattttt tatcaagttg agtgtcaagt
     6181 aaaagcgtat actttcttaa tgtaactgcg aataaagtag agatactagc aactggccaa
     6241 aaaacattct ttttagcagg tttaacaata tttaaatttt caaactcttc tctactaatt
     6301 ttgacgtatc ttttggggat gaaccaatta ataaaaggaa aaaataaact aatccaagtg
     6361 cttattatat cgatcattaa gtactcatca ttatatttaa taattctata ttttgggttt
     6421 ttattgatga ttttagattc gcacagcaat gtttacaccc cctaattagc aattgaaaac
     6481 caactaaatt tgtaactatt tattagactt taaaaatata tgtacttttt tatctataat
     6541 tgagtgcata ttcattaaca taaatagcat agtcatgaaa agccaagaaa tatataagat
     6601 taaattttgt acattttcaa acaccaacaa gtaaaatgcc ccataagaca
//
LOCUS       DAPDIM010000103         6563 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000103 DAPDIM010000000
VERSION     DAPDIM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6563
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.104"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(7..594)
                     /gene="clpP"
                     /locus_tag="RFE25_002623"
     CDS             complement(7..594)
                     /gene="clpP"
                     /locus_tag="RFE25_002623"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDU2817643.1"
                     /translation="MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSI
                     VSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSF
                     LLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQ
                     SIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK"
     gene            complement(1060..2004)
                     /gene="whiA"
                     /locus_tag="RFE25_002624"
     CDS             complement(1060..2004)
                     /gene="whiA"
                     /locus_tag="RFE25_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDU2817644.1"
                     /translation="MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVI
                     NVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGI
                     LKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGL
                     TKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNS
                     VNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLK
                     ELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL"
     gene            complement(2115..3110)
                     /locus_tag="RFE25_002625"
     CDS             complement(2115..3110)
                     /locus_tag="RFE25_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDU2817645.1"
                     /translation="MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGK
                     IRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITN
                     DFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLE
                     PNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVM
                     TQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKA
                     ELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK"
     gene            complement(3107..4018)
                     /gene="rapZ"
                     /locus_tag="RFE25_002626"
     CDS             complement(3107..4018)
                     /gene="rapZ"
                     /locus_tag="RFE25_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499344.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDU2817646.1"
                     /translation="MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPP
                     VLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEAS
                     TEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELK
                     ERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDK
                     DVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERL
                     GNYLNEVFEYNVYVHHRDAHIESGEKK"
     gene            complement(4904..5839)
                     /gene="trxB"
                     /locus_tag="RFE25_002627"
     CDS             complement(4904..5839)
                     /gene="trxB"
                     /locus_tag="RFE25_002627"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDU2817647.1"
                     /translation="MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMA
                     NTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKEL
                     TAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEG
                     TFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTL
                     TSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAG
                     DVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA"
     gene            complement(5906..>6563)
                     /locus_tag="RFE25_002628"
     CDS             complement(5906..>6563)
                     /locus_tag="RFE25_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817648.1"
                     /translation="ASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKL
                     KQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTES
                     IWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQG
                     ELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
                     "
BASE COUNT         2029 a         1270 c          887 g         2377 t
ORIGIN      
        1 tttgaattat tttgtttcag gtaccatcac ttcatcaatt aagccatatt ctttagcttc
       61 ttctgcagtt aagaagttat cacgatctgt gtctttttgt attttttcaa tactttgacc
      121 agtacgctct gataaaatgc ggtttaattt ttcacgtgtt tttaaaatgt gatttgcagc
      181 aatttcgatt tcagttgctt gtccttgagc accacctaat ggttggtgaa tcattacttc
      241 tgcatttggt aacgcgaaac gtttaccttt tgcaccagct gctaataaga atgatcccat
      301 tgatgcagcc ataccgatac aaattgtttg aacatcaggt ttaatgtgtt gaattgtatc
      361 ataaatcgca aaaccagctg ttacacttcc acctggtgaa ttaatgtata aataaatatc
      421 tttctctgag tcttgcgctt gtaagaataa taactgtgat acgattgaat ttgctacgtt
      481 gtcatcaatt tgtgaaccta acataataat acggtctttt aataaacgtg agtatatatc
      541 atatgcacgt tcaccgcggt ttgttgtttc aataactgta ggaattaaat tcatctatat
      601 ttcctccttg taataactgt tactcattat tttacatatt aagtcaaatt tggtcaaaca
      661 ctttgacttt aaatagttac attgtttgac gcttttctct ttcctttgta aactgataat
      721 atctatttta gattgtactt attttacttc tcatagtaca gagatatgat tacatatttg
      781 ctccttgtgg tgtaatggat aacacgtaag attccggttc ttaagatagg ggttcaattc
      841 ccttcaagga ggctgtttta ataaaataca atttttctta tgaccaaatt gatacatatg
      901 atgctactta atgagaaaat taggtaacgc ttggttattg aatttccttc attaaacttt
      961 ccagctcaat ttaatagtta gtcgactatt attcattaaa cactttttaa tcataaaaaa
     1021 ggtatttttg ataattcact accaaaaaca ccttcttact tataattcta tttgttcacc
     1081 atttctaatc ttatcggcta aatcattaag ttttcttaat cggtgattta cacctgattt
     1141 tgaaattgga ccagttgata ccatttctcc aagctctttc aacgaaattt cttgatgttc
     1201 tactcgaatt ctagcaatct ctctcaacct gtctggtaaa ttttcaatac caatttcttt
     1261 atcaatcaat ttaatgctct caacttgttt catcgcagca ctaactgttt tatttagatt
     1321 tgccgtttca caattaacga gtcggttaac agaattacgc atatctctta caatacgtac
     1381 gtcttcaaat tttaataacg cttgatagcc acctatcaaa ctaagaaaat ccgaaatctt
     1441 ttccgcttct tttaaatacg taatacttcc tttttttcgc tctaaatgtt tggcattcaa
     1501 ctcataacta ttcattagtt tcgttaagcc ttctgcatga ctctcatttt gagaaaaaat
     1561 ttccaaatgg tacgaagatg tttcagggtt attcactgag ccacctgcca gaaaagctcc
     1621 tctcaagtaa ctgcgtctca tttcatcatc ttgaatcatt gaatgatcaa tttcatgcgt
     1681 aaaaatgccg tcttttaaaa ttcctaattc atcaagaatt tctttcgctt tcatctttgt
     1741 acgacaaata taaatattat tttttttaag cttcattttt ttacggacta atatttcaac
     1801 ttccacatta aagacacgtt taatcaacga ataaatacgt cttgccgttg ttgcattttc
     1861 cgtttgaaca tttataacaa attgttgatt tgaaagacta agtgcaccat tcattcgaat
     1921 cagcgcactg agctctgctt ttgcattcat ttcatcgacg tctattctag ttaattcatt
     1981 tttcatttct gatgcaaagc tcatcgtaca gtcattcctt tcttatttaa aacatgattc
     2041 accttagaac cactgtctat tttcattttt ttacacagct ctattatcat atcataatat
     2101 gattacgttc tatattattt acgtttatca cttggtacga aaggaatagt actaattaat
     2161 tctaaagcta tatcataaat cattgtcgat aacactttag tattatgtct tactaaatga
     2221 ttttcagaaa tttcaactaa atttgaagat gtttttacat ttatgctttc tttttcaagt
     2281 tcagccttat taacttcaac tggtttagaa tgtttttctt catatttttt caaaacttga
     2341 gcattgaaag tttgtgtact acaaatgaca taatcaataa acggttgtcc agcttgtcta
     2401 tgaatcgcat cgatatgatc tttcacgcta taaccatctg tttccccagg ttgcgtcatc
     2461 acattagaaa catatagctt aggcgcatca gaatgaatta acgcatctga aataccattg
     2521 acacataagt tagaaataac gctcgtatat aatgaccctg gtccaagaac gattaaatct
     2581 gcttccctta aagcatcgat tgcttcttcc attggttgca catcgttagg ttctaaaaac
     2641 acacgatcaa tttttttatg ttttttagga atatttgttt ctccaaaaac aatttctcca
     2701 tcttccataa cagcatttaa ttgcacactt gtatttgtag atggaatgac tctaccttta
     2761 atatttaaaa ttttacttaa tgctttaatg gcatgtccga aatcattcgt aatattagtc
     2821 atacctgcga ttaataaatt acctaatgag tgaccgctaa tttgattttc ttcaaagcga
     2881 tactgaaaaa gttggcttaa aactgactca gaatcactta aagctgcaat cacatttctg
     2941 atgtctcctg gtgctggtat atccatttca tctctgattt tccctgtact cccaccatta
     3001 tcagcaactg ttacaatcgc cgtaatatca attgggaatt ctcttaatcc cctagccata
     3061 actgataagc cagtgccacc accgataagt acaactttta tttgtctcat tttttctcgc
     3121 cactttcaat atgtgcgtcc ctatgatgca cataaacatt atattcaaat acttcattta
     3181 gataattacc tagtcgttct gctaatgcta cagatcgatg ttgtccaccc gtacaaccga
     3241 tggcaattac taattgagat ttcccttctt ttttataccc gggtatcata aaatctaaca
     3301 aatcagttaa tttttcaaag aaaatctccg tctctttcca tttcataaca taattataaa
     3361 cgtctttatc taatcctgtt aaaggtctta aatctactac ataatatgga tttggtaaaa
     3421 atcgtacatc aaatactaaa tctgcatcca tctgaattcc atgtttaaaa ccgaaacttg
     3481 tgacattaat tgtaaaagtt tcaaactctt catcttcata gtatcgacga atgcgttctt
     3541 ttaattcttt aggtgataac tttgtagtat ctataacaaa attagctata cttctaattt
     3601 gagacaaatg ctctcgctca tcattaattg cattaattaa ggatctttta ccttgttcca
     3661 tcaaaggatg tgcacgacgc gtttctttat atcttgaaat taatttttca gtacttgctt
     3721 ctaaaaacat aacatcaatg atgacgtcac tttcactttt aactttatcc actactgcaa
     3781 ctaatgaatt aaatagttcc ttacctctta aatcaattgc aattgccact tttcttaagg
     3841 atggatttcc ttgttccatc aactctacaa atttaggcaa taacactggt ggtagattat
     3901 ctacacaaaa atatcccatg tcttctaaac attgaataac caaagattta cctgctccag
     3961 ataaacctgt tacaactaat agttcacttt tacttttttc tttttcatta ttatccatta
     4021 ttttttcacc gccaaaacga atttcatgat gttaatttaa atgttctatg acaaaattaa
     4081 gcaacgatgt tttatattta tttccaacta tgtctagatt aaatttctaa aaatatacat
     4141 catttaaagg agcttgggac ataaatcaat gtcctagggt ctataatatt atattgctag
     4201 tagttgactg aatgaaaatg cgcttgcaac aagctttttt caactctagt caggggcccc
     4261 aacacagaga aattggattt ccaatttcta cagacaatgc aagttggggt gtgggcccca
     4321 acacagagaa tttcgaaaag aaattctaca ggcaatgcga gttggggtgt gggccccaac
     4381 acagagaaat tggatttcca atttctacag acaatgcaag ttggggtgtg ggccccaaca
     4441 aagagaattt cgaaaagaaa ttctacaggc aatgcgagtt ggggtgtggg ccccaacaca
     4501 gaagcttacg ataagtcagc ttacgataat gtgcaagttg gggtggtaca acgataaagt
     4561 aatacttttt ctatagaaat tagtatttct tatgcatgag ttttactcat gtattcctat
     4621 ttttaagtac acattagctg tggctaatgt ataagaacca ctacataata aatcattagt
     4681 ggctctttat catttctgtc ccactcccat aaagttataa gtttaatata acatataaaa
     4741 aaaactagaa ctcattgaaa cgcacaaatg atacgtacta agttctagtt ttctatataa
     4801 tttgctttaa tttaaaagta agacattatt ttaacaaggt gatgacacta ttaaaataaa
     4861 tatccaaata acttacaact caacatctta attcgacctc gaattaagct tgatcgttta
     4921 aatgttcaat atattccgct gcactttgcg ctgcaatact accatcgcca gtagcagtga
     4981 caatttggcg taaacctttg tcacgaacat ctcctgctgc aaaaatacct ggtactgatg
     5041 ttgtcatatc atcttttgtc acaatataac caacatcatt cgtaatacct aagtctttaa
     5101 atggcgctgt taatggtttc ataccaatat agatgaatac accatcagcc tcgtgtgttt
     5161 cttctgaacc atcttttgta gacgttaatg tcacagaacc cactttgccg tctttttcat
     5221 taattgattt caaagtatga ctccaaataa agtcgatttt atcatttttg aatgctctat
     5281 cttgtaaaat acgctgtgca cgtaactcat cacgacggtg aacgattgtt actttgtcag
     5341 caaatttagt taagaatgtt ccctcttcta ctgctgagtc accaccaccg ataacgaata
     5401 ggcgtttatt tttaaagaat gcaccatcac atactgcaca ataacttaca ccgcgtccac
     5461 caagttcttg ttcacccgga acaccaattt tcttgtattc tgcacctgta gcaataatga
     5521 ccgctttcgc tgttaattct ttattaccaa agttaatcac tttatattcg cctttatctt
     5581 ctacagattt aatatctcca tattgataaa ctgcaccaaa ctttttagcg tgttcaaaca
     5641 tttttgtaga taaatctgga cctgtaatca tttcgaaacc agggaagttc tctacttctt
     5701 ctgtattagc catttgaccg cctggaatac ctctttcaat cataactgtt tttaaattag
     5761 cacgtgatgc gtatactgca gcagtcatac cagctggacc tgcaccgata attgctatat
     5821 caaaatctat ttcagtcatt ttattaacgc ctcctcatta ttaatcatta tgcgcattat
     5881 ataataaatc taacttttca taaatctata tgctcaagag aaattcaatc attttgttca
     5941 gtttatattg tgttatgcct aaccatgttg taatttgctt ctttgtaacg tttcgaggtt
     6001 gatttttaaa atacaaataa ataaacgcac cgatatatgg ctcaacatca gttaaatcta
     6061 ctttttcagc aattatgagt tcaccttgat taatccatgc aaccattaaa tcattttcac
     6121 ttacaaataa ttcattttgg taaagcgtta acaagccgcg atgaatgaag tctaatttat
     6181 tgagcgttaa accttgaact aaatacgtta aatacaattt ctcataatta tttagatttt
     6241 ccagaacctg ccaaatactt tccgtcatca caatttcttt accatttaat tgatccaata
     6301 aaaaaatacc atataaacga taatgactgt catcactttg aagtaatggc aaaatatgtt
     6361 ggtcaaaaac ttctttgcta ttttcaatta cccaaggcgc atgtccaatt tccactttag
     6421 aaatttgctt caatttatcc cagtagtaat gactttcgtc ttcttcacct aaataataat
     6481 aattatatgc taaagcattg tacatttgaa ttgataaaaa tttccctttt ttatataaag
     6541 ggtacaacaa ttgttgtgat gca
//
LOCUS       DAPDIM010000104         6496 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000104 DAPDIM010000000
VERSION     DAPDIM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6496
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.105"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            155..1384
                     /locus_tag="RFE25_002629"
     CDS             155..1384
                     /locus_tag="RFE25_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HDU2817649.1"
                     /translation="MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPC
                     KDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGIN
                     GVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQ
                     HGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRG
                     AIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMA
                     DNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEAT
                     HINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIE
                     VDPQDVYDKTMKLTDLQ"
     gene            1579..2436
                     /locus_tag="RFE25_002630"
     CDS             1579..2436
                     /locus_tag="RFE25_002630"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDU2817650.1"
                     /translation="MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKE
                     LAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQ
                     QKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFI
                     LFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGD
                     INLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEI
                     LKIHQEVTK"
     gene            2436..3380
                     /locus_tag="RFE25_002631"
     CDS             2436..3380
                     /locus_tag="RFE25_002631"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDU2817651.1"
                     /translation="MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERET
                     KKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLN
                     GRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAY
                     PGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTY
                     SVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDVEQQA
                     LAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE"
     gene            3649..4617
                     /gene="pfkA"
                     /locus_tag="RFE25_002632"
     CDS             3649..4617
                     /gene="pfkA"
                     /locus_tag="RFE25_002632"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002462395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDU2817652.1"
                     /translation="MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGL
                     LNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGG
                     DGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTAS
                     SHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHS
                     IVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDL
                     LMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI"
     gene            4639..6396
                     /gene="pyk"
                     /locus_tag="RFE25_002633"
     CDS             4639..6396
                     /gene="pyk"
                     /locus_tag="RFE25_002633"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDU2817653.1"
                     /translation="MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHK
                     GRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPE
                     KFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL
                     PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFP
                     KIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITA
                     TQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSA
                     EAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYR
                     PHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLI
                     IITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDK
                     VIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNM
                     LVTIDAAQGKIFEGYANVL"
BASE COUNT         2293 a          873 c         1335 g         1995 t
ORIGIN      
        1 attattttat tatcgtttat cgctatttgt gttacataat caaaaccata aattcttact
       61 cattcagatt tacccaatat ttttactttt ataatgtaat gcgttttatc caagttattt
      121 tttaaaaata aatattgaat taggggctga tttcatgtca ttaagagatg aagcattgga
      181 aatgcacaaa cgtaatcaag gtaaattaga agttaaacca aatgtaaaag ttactaataa
      241 agaggaatta agtttagcat actcacctgg cgttgctgaa ccgtgtaaag atatttatga
      301 agataaaaga aaagtatatg attacacaat taaaggaaat acagttgcag ttattactga
      361 tggaacagcg gtattaggtt taggtaacat tggacctgaa gcaagtattc ctgtaatgga
      421 aggtaaagca gtattattca aaagcttcgc tggtatcaat ggggtgccta ttgcgttaaa
      481 tacaactgat accgaagaaa tcattaaaac agttaagttg ttagaaccta attatggtgg
      541 tattaattta gaggatattt cggcaccacg ttgttttgaa attgaagaac gattgaaaaa
      601 agaaactaat attccggtat tccatgacga tcaacatggt acagcaattg taacaatggc
      661 aggtttggta aatgcattga gagttgttaa caaagatatt gctaaaataa aagttgtact
      721 aaatggtgct ggtgcagcag gaatagccat tgttaaatta ctatacgcgt atggtgtaag
      781 aaatatggtt atgtgtgact caagaggcgc aatttttgaa ggacgttcat atggtatgaa
      841 tcctacgaaa gatgttgtag ctaaatggac aaataaagat aagattgaag ggtctttaga
      901 agaagtcgta aaagacgcag atgtatttat cggagtttct gtagctaatg cgctgtcaca
      961 agatatggtt aagagtatgg cagataatcc aattatattt gcaatggcta atccaaatcc
     1021 tgaaataata cctgatgatg ccaaagcggc aggtgcacga gttgttggta caggacgttc
     1081 agactatcct aaccaaatta ataatgtatt agctttccct ggtattttta gaggtgcatt
     1141 agaggttgaa gctacacata taaatgaaga aatgaaaaag gcagctgtag aagcgattgc
     1201 tgatttaatc gatagttctg aattaaatga agactactgt atcccaggac cgtttgataa
     1261 acgtgtagcg ccatcagttg ctcgtaatgt tgctaaagcg gcaatggaat ctggagtagc
     1321 taggattgaa gttgatccgc aagatgtgta tgataaaaca atgaaactta cagatttaca
     1381 ataaaaataa ttaacgttta attaaattgc ttaaaagtta gcaataaaga gtcattaaaa
     1441 tgatgaaaat gaaagtttat gataaacatt caacagtcaa acgaatataa atcaaataaa
     1501 tttaaacccg tttttaactg gtcaagttca gtttaaggct ctaaatggtt agaacagagg
     1561 ttatttggag gttttcctat gtttaaagat ttttttaatc gaacaaagaa aaagaaatat
     1621 cttacagtac aagactctaa aaataatgat gtgcctgcag gtattatgac taagtgtcca
     1681 aagtgtaaga aaattatgta cacaaaagaa ttagctgaaa atttaaatgt gtgctttaat
     1741 tgtgatcatc atattgcttt aactgcgtat aaacgtatag aagcaatttc tgatgaagga
     1801 tcatttacag aattcgataa gggaatgacc tctgcgaatc cattagattt tccaagttat
     1861 ttagaaaaaa ttgaaaagga ccaacaaaag acaggtctta aagaagcagt tgtgactggt
     1921 acagcgcaac tagatggtat gaaatttggc gttgctgtca tggattcacg ttttagaatg
     1981 ggaagtatgg gatcggttat cggtgaaaag atatgtcgca tcattgatta ctgcactgag
     2041 aaccgtttac catttattct tttctctgca agtggtggtg cacgtatgca agaaggtatt
     2101 atttccttga tgcaaatggg taaaaccagt gtatctttaa aacgtcattc tgacgctgga
     2161 ctattatata tatcatattt aacacatcca actactggtg gtgtatctgc aagttttgca
     2221 tcagttggtg atataaattt aagtgagcca aaagcgttga taggttttgc aggtcgtcga
     2281 gttattgaac agacaataaa cgaaaaattg ccagatgatt tccaaactgc agaattttta
     2341 ttagagcatg gacaattgga taaagttgta catcgtaatg atatgcgtca aacattgtct
     2401 gaaattctaa aaatccatca agaggtgact aaataatgtt agattttgaa aaaccacttt
     2461 ttgaaattcg aaataaaatt gaatctttaa aagaatctca agataaaaat gatgtggatt
     2521 tacaagaaga aattgacatg cttgaagcgt cattggaacg agaaactaaa aaaatatata
     2581 caaatctaaa accatgggat cgtgtgcaaa ttgcgcgttt gcaagaaaga cctacgaccc
     2641 tagattatat tccatatatc tttgattcgt ttatggaact acatggtgat cgtaatttta
     2701 gagatgatcc agcaatgatt ggtggtattg gctttttaaa tggtcgtgct gttacagtta
     2761 ttggacaaca acgtggaaaa gatacaaaag ataatattta tcgaaatttt ggtatggcgc
     2821 atccagaagg ttatcgaaaa gcattacgtt taatgaaaca agctgaaaaa ttcaatcgtc
     2881 ctatctttac atttatagat acaaaaggtg catatcctgg taaagctgct gaagaacgtg
     2941 gacaaagtga atctatcgca acaaatttga ttgagatggc ttcattaaaa gtaccagtta
     3001 ttgcgatagt cattggtgaa ggtggcagtg gaggtgctct aggtattggt attgccaata
     3061 aagtattgat gttagagaat agtacttact ctgttatatc tcctgaaggt gcagcggcat
     3121 tattatggaa agacagtaat ttggctaaaa ttgcagctga aacaatgaaa attactgccc
     3181 atgatattaa gcaattaggt attatagatg atgtcatttc tgaaccactt ggcggtgcac
     3241 ataaagatgt tgaacagcaa gctttagcta ttaaatcagc gtttgttgca cagttagatt
     3301 cacttgagtc attatcacgt gatgaaattg ctaatgatcg ctttgaaaaa ttcagaaata
     3361 tcggttctta tatagaataa tcaacttgag catttttatg ttaaatcgat actgggtttt
     3421 accataaatt gaagtacatt aaaacaataa tttaatattt agatactgaa ttttaactaa
     3481 gattagtagt caaaattgtg gctactaatc tttttttaat taagttaaaa taaaattcaa
     3541 tatttaaaac gtttacatca attcaataca ttagttttga tggaatgaca tatcaatttg
     3601 tggtaattta gagttaaaga taaatcagtt atagaaaggt atgtcgtcat gaagaaaatt
     3661 gcagttttaa ctagtggtgg agattcacct ggaatgaatg ctgccgtaag agcagttgtt
     3721 cgtacagcaa tttacaatga aattgaagtt tatggtgtgt atcatggtta ccaaggattg
     3781 ttaaatgatg atattcataa acttgaatta ggatcagttg gggatacgat tcagcgtgga
     3841 ggtacattct tgtattcagc aagatgtcca gagtttaagg agcaagaagt acgtaaagtt
     3901 gcaatcgaaa acttacgtaa aagagggatt gagggccttg tagttattgg tggtgacggt
     3961 agttatcgcg gtgcacaacg catcagtgag gaatgcaaag aaattcaaac tatcggtatt
     4021 cctggtacga ttgacaatga tatcaatggt actgatttta caattggatt tgacacagct
     4081 ttaaatacga ttattggctt agtcgacaaa attagagata ctgcgtcaag tcacgcacga
     4141 acatttatca ttgaagcaat gggccgtgat tgtggagatc tagcattatg ggctggatta
     4201 tcagttggtg ctgagacaat tgtagttcca gaagtgaaaa cagatattaa agaaatagct
     4261 gataaaattg aacaaggtat taaacgtggt aagaaacact caatcgttct tgtagcagaa
     4321 ggttgcatga ctgcgcaaga ttgtcaaaaa gaattatcac aatacatcaa tgttgataat
     4381 agagtgtctg tgttaggtca cgttcaacgt ggtggtagcc caacaggtgc ggatagagtt
     4441 ttagcatcac gtttaggtgg atatgcggta gacttattaa tgcaaggtga aacagctaag
     4501 ggtgttggaa ttaagaacaa taaaattgta gcaacatctt ttgatgaaat ttttgatggt
     4561 aaagatcata aatttgatta tagtctatat gaacttgcta acaagttatc tatataagat
     4621 ttcaggagga attataaaat gagaaaaact aaaattgtat gtacaattgg accagcttca
     4681 gaatcagaag aaatgattga gaaattaatc aatgctggta tgaacgttgc acgattaaac
     4741 ttttcacatg gtagtcatga agagcataaa ggtagaattg atacaattcg taaagtagct
     4801 aaaagattag acaaaattgt agcaatttta ttagatacga aaggtccaga aattcgtacg
     4861 cataatatga aagacggtat cattgaactt gaacgtggta acgaagttat tgttagcatg
     4921 aatgaagttg aaggaacacc tgaaaagttc tcagtaacat atgaaaactt aattaacgat
     4981 gttcaagtag gttcatacat tttacttgat gatggcttaa ttgaattaca agttaaagat
     5041 attgaccatg ctaaaaaaga agttaaatgt gatattttaa actctggtga gcttaaaaac
     5101 aaaaaaggtg ttaacttacc tggtgtaaga gtaagtttac ctggtattac agaaaaagat
     5161 gctgaagata tccgtttcgg tattaaagaa aatgttgact tcattgcagc aagtttcgta
     5221 cgtcgtccta gtgatgtttt agaaattcgt gaaattttag aagaacaaaa agctaacatt
     5281 tcagtattcc ctaaaattga aaaccaagaa ggtattgata atattgcgga aattcttgaa
     5341 gtgtctgatg gtttaatggt tgcacgtggt gacatgggtg ttgaaattcc acctgaaaaa
     5401 gtaccaatgg ttcaaaaaga tttaatcaga caatgtaaca aattaggtaa accagttatt
     5461 acagctacac aaatgttaga ttctatgcaa cgtaacccac gtgctacacg tgcagaagct
     5521 agtgacgttg ccaacgcaat ctatgatggt acagatgcag taatgttatc tggtgaaact
     5581 gctgctggtt tatatcctga agaagctgtt aaaacaatga gaaatattgc tgtatcagct
     5641 gaagcagccc aagattataa aaagttattg tcagatcgta ctaaattagt tgaaacttca
     5701 ttagtgaatg ctatcggtat ttcggttgca catacagctt taaacttaaa tgttaaagca
     5761 attgtagctg ctactgaaag tggttcaacg gcacgtacta tctctaaata tcgtccacat
     5821 tcagacatta ttgcggtgac tccaagtgaa gaaacagcac gtcaatgttc aattgtttgg
     5881 ggagttcaac ctgtagttaa aaaaggacgt aagagtacag atgcattgtt aaacaatgca
     5941 gttgcaacag ctgttgaaac tggtagagta tctaatggtg atttaatcat tattactgct
     6001 ggtgtaccaa ctggtgaaac tggaactact aatatgatga aaatccacct agttggtgac
     6061 gaaattgcta atggtcaagg tattggacgt ggatcagttg ttggtactac gttagttgct
     6121 gaaactgtta aagatttaga aggtaaagat ttatctgaca aagttatcgt tactaactca
     6181 atcgatgaaa cgtttgtacc ttatgtagaa aaagctttag gattaattac agaagaaaat
     6241 ggtattacat caccaagtgc aattgttggt ttagaaaaag gtattccaac agttgtaggt
     6301 gtagaaaaag ctgttaaaaa cataagcaat aacatgttag ttacgattga tgctgctcaa
     6361 ggtaaaatct ttgaaggata tgcaaacgta ctataattta taaaaaaacg tctttccatt
     6421 tatcaacaat ggaaaggcgt tttttggttc atctggtatt ttatgacgta attaataggt
     6481 tatttgataa tgatag
//
LOCUS       DAPDIM010000105         6475 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000105 DAPDIM010000000
VERSION     DAPDIM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6475
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.106"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..199
                     /locus_tag="RFE25_002634"
     CDS             <1..199
                     /locus_tag="RFE25_002634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817654.1"
                     /translation="EAFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTDRKGH
                     VIGMLEWALDYIVGNIEVEEL"
     gene            200..523
                     /locus_tag="RFE25_002635"
     CDS             200..523
                     /locus_tag="RFE25_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1474 family protein"
                     /protein_id="HDU2817655.1"
                     /translation="MNWEIRNLMCNIEIVKEKLEDVATTHTWFVDGRFTKRSLKTKEE
                     VVNYGLAYNEHRIHNEQVTELMLTYLEELDGLMNKFHEIEKASLSTDQSESNANVQSI
                     YLNKY"
     gene            568..2184
                     /locus_tag="RFE25_002636"
     CDS             568..2184
                     /locus_tag="RFE25_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage resistance protein"
                     /protein_id="HDU2817656.1"
                     /translation="MDEVSLYKKHFEFHSKLDYVSTINLSRIKEISKRINFASISTDR
                     QVFNNKGNAYHREKDNVAGDYISNLTLDYTIKPKEIGLVYGTVNIKTVDKNGEEEKQS
                     TFKTSHFHNYARFIADLISDRVIYSKQLDCFIIVKNNQYEVIDNTNFALTYPVDNKYY
                     IDDFLDVMLELYREHLNVTHNFKIYPYCIAGNDWVYDCQNLTLTEQKLKSDELYSIKY
                     DVDIKDINLEIPRNFFDLVTDNKKSKNNLMLTHAYTMYRKMKLIQAEKWFLLKDFGRS
                     GKGLFMATFEKLMTVNKVNFDSLISGGFESANEWMNFYGADIAHANETGEITKQMMRI
                     LRKIATGETISGRGIGRNAFTFKNNAVLILDTNESVDTGEITANTTRTVKISLKDRPI
                     NETDEERYQIFKPYWDFIQPNGNTSVNASVSFLITSLEYLKENGREFKFKDVTLKYYF
                     NEDELTETQITMIRLLSKQGFILAGDETLQRLIEQDYSSLRYKNAKEDMRKIGISINN
                     QKKIDGVNTKVHKVGNIELFNMALELISEH"
     gene            2360..3163
                     /locus_tag="RFE25_002637"
     CDS             2360..3163
                     /locus_tag="RFE25_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HDU2817657.1"
                     /translation="MTGYHVAKHLLSKNIEVIPLNNHKKPTVSFADIDITDEFVEYHS
                     NIYHQTNVLGVLTRGVWCIDIDVDHEDGKNGFDSLKQIPYYEELVTNAQNTLVQTTAS
                     GGKHIIFKKHDNIEYGQKIGYLPSVDIKAHPNNYFVLAGSQTAKGIYTHNGVNVTEYQ
                     GEFEKRIFSKAGNYKQQVLEPYSIRRALPNYSFSHVRVGKGGEGKRAYQRIIDGQSEY
                     RNNDLYKAVSYAIQCNVDIEPLRVLIGDNKNGDVFTERDWEATVRSASR"
     gene            3150..3422
                     /locus_tag="RFE25_002638"
     CDS             3150..3422
                     /locus_tag="RFE25_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817658.1"
                     /translation="MQAVKEDYNLDEQAQRIGLITGISNEIYYCSISYLSTVYLEYID
                     NTWTAWRESYIPKLNKRTSYKVIASGSFELVLARLKSYLNYIKRSK"
     gene            3424..4065
                     /locus_tag="RFE25_002639"
     CDS             3424..4065
                     /locus_tag="RFE25_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012990921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817659.1"
                     /translation="MNIETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDM
                     VYVMMNSKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKHLSISD
                     MMASHLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLY
                     QLATGINEPEPELVEGLKLVTEFIQDENATQEDYKALERKLNDLKASYYSLSK"
     gene            4515..4856
                     /locus_tag="RFE25_002640"
     CDS             4515..4856
                     /locus_tag="RFE25_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001668138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817660.1"
                     /translation="MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEY
                     NSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIFTTEQEKQQAMRSIKKLADGSM
                     KRYEALKRIKV"
     gene            4868..5446
                     /locus_tag="RFE25_002641"
     CDS             4868..5446
                     /locus_tag="RFE25_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817661.1"
                     /translation="MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKIDKSTYKQ
                     LIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSS
                     LYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEARE
                     ALNGYFRENIFTSYINGNDLPYEHNNKLFLKR"
     gene            5464..5682
                     /locus_tag="RFE25_002642"
     CDS             5464..5682
                     /locus_tag="RFE25_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001662729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid morphogenesis B protein"
                     /protein_id="HDU2817662.1"
                     /translation="METKYELNNTKKVANAFGLNEADTNLLINAVDLDIKNNMQEISS
                     ELQQSEQSKQKQYGTTLQNLAKQNRIIK"
     gene            5733..6260
                     /locus_tag="RFE25_002643"
     CDS             5733..6260
                     /locus_tag="RFE25_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDU2817663.1"
                     /translation="MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQI
                     ESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSINNTALLKKVL
                     NHYTEKEQKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKI
                     ARVNAYHQSSYVKVV"
     gene            6263..>6475
                     /locus_tag="RFE25_002644"
     CDS             6263..>6475
                     /locus_tag="RFE25_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817664.1"
                     /translation="MDKKQIKDFVCDYHKRTRSDVLIDDEINTDEFFSIGDENSNEWM
                     ADDNIDDHIVKNHLEMIVDQVANDKEF"
BASE COUNT         2550 a          819 c         1233 g         1873 t
ORIGIN      
        1 tgaagcattt ttaattcttg atgaagtaac aatgacgcta agtgatgtca tgaaagaaac
       61 acaacacgtt taccgttata gtgtcataga cgaaaaaggt gaacataaac atacaacaga
      121 tcgcaaagga cacgtgattg gaatgttaga gtgggcatta gattacattg tgggaaatat
      181 tgaagtggag gaattataaa tgaattggga gattagaaat ttaatgtgca atatagagat
      241 agtaaaagaa aagttggaag atgtagcgac tacacataca tggtttgtag atggacgatt
      301 tacgaagaga tcgttaaaaa ctaaagaaga agtggttaat tacggtctag cgtataacga
      361 acatagaatt cacaacgaac aagttacaga attaatgctt acttatttgg aagaattaga
      421 cggtttaatg aataagtttc atgaaataga aaaagcgtca ctctccaccg accaaagcga
      481 aagtaacgca aatgtacaaa gtatttattt aaataaatac tagtaaatat attaacaaaa
      541 ataaaatgat atcgaaagga tgactacatg gacgaagtat cactttataa aaaacatttc
      601 gaatttcatt ctaaattaga ttatgtttca acgattaatc tatctaggat aaaagagata
      661 agcaagcgta taaactttgc atcaatctca acagatagac aagtttttaa taacaaagga
      721 aatgcatatc accgagaaaa agataatgtt gcgggtgatt atattagtaa tcttacttta
      781 gattatacca taaaaccaaa agaaattggg cttgtttatg gaaccgtcaa tatcaagact
      841 gttgataaaa atggtgaaga agaaaaacaa tctacgttta aaactagtca ttttcataac
      901 tatgcacgtt ttatagctga tctaatttct gacagggtca tttattcaaa acaactagac
      961 tgctttatta tagttaagaa taaccagtat gaagtgatag acaatacaaa ctttgcgtta
     1021 acctatccag ttgataacaa gtactatatt gatgatttct tagatgtgat gttagagctt
     1081 taccgcgaac atttaaatgt aactcataac tttaagattt atccatattg cattgcaggt
     1141 aatgactggg tatatgattg ccaaaattta acgcttacag aacaaaaatt aaaaagtgat
     1201 gagctctact caattaaata tgacgtagat attaaagata tcaatttaga aatacccaga
     1261 aacttctttg atttagtaac tgacaataaa aagagtaaaa acaatttaat gctaacacac
     1321 gcttatacaa tgtatcgaaa aatgaaattg atacaagcag aaaagtggtt tttacttaaa
     1381 gattttggtc gttctggaaa aggtttgttt atggctacat ttgaaaaatt gatgacagtg
     1441 aacaaagtta attttgatag ccttatttct ggtggttttg aatcggcaaa tgagtggatg
     1501 aatttttacg gtgcagatat agctcatgct aatgagacag gtgaaatcac taaacaaatg
     1561 atgcgcatat taagaaaaat agcaacaggt gaaacaattt ctggacgtgg cattggaaga
     1621 aacgcattta catttaaaaa taacgccgta ttaatactag atacaaatga aagtgtcgat
     1681 actggtgaaa ttacagctaa tacaacacga acagttaaaa tatcactaaa agatagacct
     1741 ataaatgaaa ctgatgaaga acgttatcag atatttaagc cgtattggga ttttatacaa
     1801 cctaatggca acacttcagt taatgcgtct gtgtcattct taataacgag tttggaatat
     1861 ttaaaagaaa atgggcgaga atttaaattt aaagatgtaa cgctcaagta ttattttaat
     1921 gaagatgaat tgactgaaac tcaaattact atgatcagat tgttatcaaa acaaggcttt
     1981 atattagcag gtgatgaaac attacaacgc ttaatagaac aagattactc aagtttacgt
     2041 tacaagaacg ctaaagaaga tatgaggaaa attggcatta gtatcaataa tcaaaagaaa
     2101 atagacgggg taaatacaaa agttcataaa gttggaaaca ttgaattatt taacatggct
     2161 ttagaactaa tttctgaaca ctaaggttac tgtaactctt ggtaacttat atagtaactc
     2221 taaaaatggc gttataacaa ttggtaacct atataactct tattactgta acattaatcg
     2281 ataactttta atgttgttga tgatataggt aaaaataaga gttattagag ttactggcta
     2341 cctacaaagg aggtatacaa tgacaggtta tcatgtagcg aaacacttat taagtaagaa
     2401 tattgaagtt ataccactaa ataatcacaa aaagccaact gtttcatttg ctgatataga
     2461 tattactgat gaattcgttg aatatcattc taatatttat catcaaacca atgtattggg
     2521 cgtattaaca cgaggtgtat ggtgtatcga cattgatgta gatcatgaag atggtaagaa
     2581 tggtttcgat agtttgaaac aaataccata ttacgaagaa cttgttacca atgcacaaaa
     2641 tacattagta cagacaacgg caagtggtgg gaaacatatc atattcaaaa agcatgacaa
     2701 tatcgaatac ggacagaaga taggttattt accatctgtt gatatcaaag cacatcccaa
     2761 taattatttt gtgcttgcag gtagtcaaac agctaaaggt atatacactc ataacggtgt
     2821 caatgtaact gagtatcaag gagagtttga gaaacgaata ttttctaaag ctggtaatta
     2881 caaacaacaa gtattagagc catattccat tcgacgagca ctacctaatt atagttttag
     2941 tcacgtaaga gttggcaaag gtggagaagg aaaacgtgca tatcaacgca ttatagacgg
     3001 tcaaagtgaa tataggaaca atgatttata taaagcagta agttatgcga ttcaatgtaa
     3061 cgtagatatt gagccgttac gtgtattgat tggagataat aaaaacggcg atgtatttac
     3121 ggagagagat tgggaggcga ctgttagaag tgcaagccgt taaagaggat tacaatttag
     3181 acgaacaagc tcaaaggatt ggtttaataa ctggtatatc taacgaaata tactattgtt
     3241 caataagtta tttatcaacg gtttatttag aatatattga taacacttgg actgcatggc
     3301 gtgagagtta tattcctaaa ttaaataaaa gaacaagtta caaagttata gcttcaggaa
     3361 gttttgaatt agtgctagct agattaaaga gttatttaaa ttatataaaa aggagtaagt
     3421 gatatgaaca tagaaactat tgtaaaccaa tttgaaacac gagcaggcac gttactaagg
     3481 tactacacag gattattaga acatagtaaa gtgcaaccgt gttgctttaa gttatacaat
     3541 gatccatttg atatggtata cgtgatgatg aacagcaagc tattcggtca tgtatatatt
     3601 aaagattgta aagtaaggca atcatttgaa ttagcgtcac ctaagcacac tgaggggctt
     3661 ataagaagca tagaggggca ttatgtaggt tatgaattac atgacggtaa acatctttct
     3721 attagtgata tgatggctag tcatttgttt gaagatgagt attttatgta tggattacaa
     3781 acatatgcag aatcaaataa tagtgatgtg tttgagtacc tagaaaatgg atttgataca
     3841 gatacacttg agggcattca atcaagtaat actgatgtga tagcgaatat tgaaatgttg
     3901 tatcagttag ctacgggaat caatgaacca gaaccagagt tagttgaggg attgaagttg
     3961 gtaactgagt ttatacaaga tgagaatgcg acgcaagagg attacaaggc tttagaacgt
     4021 aaattgaatg atctaaaagc gtcttactat agcttgagta aataatgtta tgaggggtca
     4081 catgtagtgt gtggctccta ataaaatact acgattttat acgaggtata gcagtttaaa
     4141 atggtaaggt tttcggaagg tgttggcttt taaaatcgga aggtatacag tctttgagaa
     4201 ttgaaaaaat ggcaagattt gtgcaaggtg tgcgaacttt gttaacgcta atacaagcta
     4261 aagtttgtgt ttttggcata ggcctaaaag ttaagtttgt tcgctgtttg ttcgtgttat
     4321 tttaccgaac ttaagttcta tattaggtta atgtgaaaag cctaacgtta agtttataac
     4381 atgattttat aagtgttata tatgataagc taaacaattg ataaaacgcg ctataaagcg
     4441 aacgtaagtt tgttttggac ctgtaaaaat ggtataattt aggtatgaaa taattaaaag
     4501 aaagaggtgt agaaatgcaa agtatcgcag aaaaagagac gtatcattta cccaccgaac
     4561 acctgcaagt tttcaatgtg ataaaaaata cgtccaataa gtatattact aaaactaaaa
     4621 tcttaaatca attgggatat gaatataatt caagcaatga acgatggtta cgaagagtaa
     4681 tcaattcatt agtatatgat tatggctatc ctatcggatg cagttataaa cctagtgaac
     4741 gtggttatta catctttacg acagaacaag aaaagcaaca agcgatgaga agtattaaga
     4801 aattagctga tggcagtatg aaacgctatg aagctttgaa acgaattaaa gtgtaaaggg
     4861 gataaaaatg aaaactgaat cgtactttaa agaatacaac caatttgtaa tagatcaaca
     4921 aaaggctata caagaattgg aacaagagcg taatgcattg gagagtaaaa taaagataga
     4981 taagtccaca tataaacagt taatcatgga tggacaagat gataaagcag ataacctata
     5041 tcaagcaaca gatgctgatg aaaagaaact aaaagcactt aataaacgct tagagacaaa
     5101 gaaaagtgtg tcgaaagaag ttaaatatca aaagacaatt gaattattaa aacatcaaag
     5161 cgagttgtca tcattatacg aatcagaaaa gcaatcagct ttaggtaaat taaaaaaagt
     5221 agtcgatgca tataatgaga tcattgatga aatagaagat attaatgata gatatgaaga
     5281 tgagcatcag caatatgcga gtatttatag tcaagaacaa ttatatgatg ataaagaggc
     5341 tagggaagca ttgaatggct actttagaga aaatatattt acatcatata ttaatggtaa
     5401 tgatttgcca tacgaacaca ataacaagtt gtttttaaaa cgttaaaaag aaagggtaat
     5461 taaatggaaa caaaatacga gttaaataat actaaaaagg tcgcaaatgc atttggttta
     5521 aatgaagcag atacaaatct attaataaat gcagttgatt tggatattaa aaacaatatg
     5581 caggagattt caagtgagtt acaacaatca gaacagtcta agcaaaagca atatggtaca
     5641 acgctacaaa atttagctaa gcaaaacagg attattaaat agcaatgatt gcctatccaa
     5701 ttcgggtagg ctctgtttat aggggtgaat aaatgaaact gcttaaaacg aagaattgtt
     5761 tatattatcg taatggcgac aataaactat ctgagtatca actattaacg caatttaacc
     5821 cagcatttat taataagaaa attaagatgt gtgaattcca aattgaaagt atgtaccata
     5881 tgagtgcgtc gaccacaaca tgtgatgaaa taatgggggt cgtgtctgtc tcatatccga
     5941 ttgaaaaatt agttatcaaa attattgaaa caaaagcagg gttacaaaac tataaaaata
     6001 gatctataaa taatacggcg ttgttgaaaa aggtactaaa tcattataca gaaaaagagc
     6061 agaagcaagt tgtaaaatat atgcgttcaa atggacgata taagccctac aacgtcattg
     6121 aacgcttaca agttgatttg tatcaagcaa gtattaaaca acgttcagaa cgtcaaaaac
     6181 aaagaaatac agcaattgaa aacagtaaga ttgcacgagt aaatgcatat caccaatctt
     6241 catatgtaaa agtggtgtaa caatggataa aaagcaaata aaagacttcg tttgtgatta
     6301 tcataagcga actagaagtg atgtgttgat agatgatgaa ataaataccg atgaattctt
     6361 ttcaataggt gatgaaaatt ctaatgaatg gatggcagac gataacattg atgatcatat
     6421 tgtaaagaat cacttagaaa tgattgttga ccaagtagct aatgataaag agttt
//
LOCUS       DAPDIM010000106         5824 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000106 DAPDIM010000000
VERSION     DAPDIM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5824
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.108"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            157..3119
                     /locus_tag="RFE25_002645"
                     /pseudo
     CDS             157..3119
                     /locus_tag="RFE25_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501257.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="E domain-containing protein"
     gene            3503..4704
                     /locus_tag="RFE25_002646"
                     /pseudo
     CDS             3503..4704
                     /locus_tag="RFE25_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501256.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            4676..4909
                     /locus_tag="RFE25_002647"
     CDS             4676..4909
                     /locus_tag="RFE25_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817665.1"
                     /translation="MLRSLCKQNRILINAIKVGIEMKYKISLAYNLAIIIGSLIILCI
                     LISRGYDIYVILIPILTILASLINLICDIKKHK"
     gene            complement(5017..5325)
                     /locus_tag="RFE25_002648"
     CDS             complement(5017..5325)
                     /locus_tag="RFE25_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817666.1"
                     /translation="MTVNIVFSIVFCISMVILGIYVAITKDFTLISYINQTTIADKHK
                     NQIAYIFTLCISLSAVFLMSSILCFEYDFIALSFLFLTIALLLIALFYVCFYKITKYP
                     "
     gene            complement(5469..5735)
                     /locus_tag="RFE25_002649"
     CDS             complement(5469..5735)
                     /locus_tag="RFE25_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817667.1"
                     /translation="MKGSKQILLIMGIISLIVLFIFTLFIMAQYAKHYEQKSDSSNAH
                     TLNSSSAIIEQHTMSNLASLDLYAPVRNITSSRDIHPIYFMTKD"
BASE COUNT         2258 a          788 c         1079 g         1699 t
ORIGIN      
        1 tatttttagt tgtagattgt tttaagtgtg tcaatatata aaataatttt ataaagataa
       61 gtgttatatt ccattgtgca actcctattg tatttgtaaa attacatgta aattcactgt
      121 aagtaaagtg gaaaatatgg aaaaaggagt atgcaaatga gagataagaa aggaccggta
      181 aataaaagag tagattttct atcaaataaa ttgaataaat attcaataag aaaatttaca
      241 gttggaacag catctatttt aattggctca ctaatgtatt tgggaactca acaagaagca
      301 gaagcagctg aaaacaatat tgagaatcca actacattaa aagataatgt ccaatcaaaa
      361 gaagtgaaga ttgaagaagt aacaaacaaa gacactgcac cacaaggtgt agaagctaaa
      421 tctgaagtaa cttcaaacaa agacacaatc gaacatgaag catcagtaaa agctgaagat
      481 atatcaaaaa aggaggatac accaaaagaa gtagctaatg ttgctgaagt tcagccgaaa
      541 tcgtcagtca ctcataacgc agaggcacct aaggttagaa aagctcgttc tgttgatgaa
      601 ggctcttttg atattacaag agattctaaa aatgtagttg aatctacccc aattacaatt
      661 caaggtaaag aacattttga aggttacgga agtgttgata tacaaaaaaa cccaacagat
      721 ttaggggtat cagaggtaac caggtttaat gttggtaatg aaagtaatgg tttgatagga
      781 gctttacaat taaaaaataa aatagatttt agtaaggatt tcaattttaa agttagagtg
      841 gcaaataacc atcaatcaaa taccacaggt gctgatggtt gggggttctt atttagtaaa
      901 ggaaatgcag aagaatattt aactaatggt ggaatccttg gggataaagg tctggtaaat
      961 tcaggcggat ttaaaattga tactggatac atttatacaa gttccatgga caaaactgaa
     1021 aagcaagctg gacaaggtta tagaggatac ggagcttttg tgaaaaatga cagttctggt
     1081 aattcacaaa tggttggaga aaatattgat aaatcaaaaa ctaatttttt aaactatgcg
     1141 gacaattcaa ctaatacatc agatggaaag tttcatgggc aacgtttaaa tgatgtcatc
     1201 ttaacttatg ttgcttcaac tggtaaaatg agagcagaat atgctggtaa aacttgggag
     1261 acttcaataa cagatttagg tttatctaaa aatcaggcat ataatttctt aattacatct
     1321 agtcaaagat ggggccttaa tcaagggata aatgcaaatg gctggatgag aactgacttg
     1381 aaaggttcag agtttacttt tacaccagaa gcgccaaaaa caataacaga attagaaaaa
     1441 aagttgaaga gattccattc aagaaagaac gtaaatttaa tccggattta gcaccaggga
     1501 cagaaaaagt aacaagagaa ggacaaaaag gtgagaagac aataacaaca ccaacactaa
     1561 aaaatccatt aactggagaa attattagta aaggtgaatc gaaagaagag atcacaaaag
     1621 atccgattaa tgaattaaca gaatacggac cagaaacgat agcaccaggt catcgagacg
     1681 aatttgatcc gaagttacca acaggagaga aagaagaagt tccaggtaaa ccaggaatta
     1741 agaatccaga aacaggagac gtagttagac caccggtcga tagtgtaaca aaatatggac
     1801 ctgtaaaagg agactcgatt gtagaaaaag aagaaattcc attcgagaaa gaacgtaaat
     1861 ttaatcctga tttagcacca ggaacagaaa aagtaacaag agaaggacaa aaaggtgaga
     1921 agacaataac gacaccaaca ctaaaaaatc cattaactgg agaaattatt agtaaaggtg
     1981 aatcgaaaga agaaatcaca aaagatccga ttaatgaatt aacagaatac ggaccagaaa
     2041 cgataacacc aggtcatcga gacgaatttg atccgaagtt accaacagga gagaaagagg
     2101 aagttccagg taaaccagga attaagaatc cagaaacagg agatgtagtt agaccaccgg
     2161 tcgatagcgt aacaaaatat ggacctgtaa aaggagactc gattgtagaa aaagaagaaa
     2221 ttccattcga gaaagaacgt aaatttaatc ctgatttagc accagggaca gaaaaagtaa
     2281 caagagaagg acaaaaaggt gagaagacaa taacgacgcc aacactaaaa aatccattaa
     2341 ctggagaaat tattagtaaa ggtgaatcga aagaagaaat cacaaaagat ccagttaatg
     2401 aattaacaga attcggtggc gagaaaatac cgcaaggtca taaagatatc tttgatccaa
     2461 acttaccaac agatcaaacg gaaaaagtac caggtaaacc aggaatcaag aatccagaca
     2521 caggaaaagt gatcgaagag ccagtggatg atgtgattaa acacggacca aaaacgggta
     2581 caccagaaac aaaaacagta gagataccgt ttgaaacaaa acgtgagttt aatccaaaat
     2641 tacaacctgg tgaagagcga gtgaaacaag aaggacaacc aggaagtaag acaatcacaa
     2701 caccaatcac agtgaaccca ttaacaggtg aaaaagttgg cgagggtcaa ccaacagaag
     2761 agatcacaaa acaaccagta gataagattg tagagttcgg tggagagaaa ccaaaagatc
     2821 caaaaggacc tgaaaaccca gagaagccga gcagaccaac tcatccaagt ggcccagtaa
     2881 atcctaacaa tccaggatta tcgaaagaca gagcaaaacc aaatggccca gttcattcaa
     2941 tggataaaaa tgataaagtt aaaaaatcta aaattgctaa agaatcagta gctaatcaag
     3001 agaaaaaacg agcagaatta ccaaaaacag gtttagaaag cacgcaaaaa ggtttgatct
     3061 ttagtagtat aattggaatt gctggattaa tgttattggc tcgtagaaga aagaattaaa
     3121 ataattcata atttaaataa tagttgattt gcattcacta tatttagttt gttaaaaaca
     3181 acctagaata tgatgagaat gatatacacc ccaaaagttg gattgaaaga cctaacttta
     3241 aggggtgtat ttttgttata aatttgattt tttgataata ttttcatatt taatataatc
     3301 ataattagta gaatataacc tctgagtagt cattttgggg ggtatgtatg gtgtttcaag
     3361 tagtatgtat atttcgaaat aattgatatt taactgactt aattttatta gaattaattg
     3421 cgctttggat aaagagagtt tagaagaagg tctaaaaaag gctggtggat gcattcaatt
     3481 atttttatga gaggtgataa atatgttgta cttagaagtt ttgaaaaata gaaactttac
     3541 atatttattg attggtaatt tcttacgtcg gagttgcttt gtgctgtttt cgttacaaat
     3601 aatttggttt actgttgaat tgacaaacca atcatcttta aaattatcaa tgatggttat
     3661 gagtcaaaca cttccattta ttatatttgg tattttcggt ggcgcatatt ctgataaaca
     3721 taataaaaag aaaatacttt atctatctga tcttatacta agtttgatta taataattat
     3781 tcctttactt gcaataacat caaatttaaa ttatctgacg cttctaacca tatctacagc
     3841 tatcaccatt attaactgct atacggatcc tgcgtttagg gcaattcttc ctgaaattat
     3901 tgatgaggag catttagcaa caagtaatgc gttaatcgat agtttgcaaa gaggctcaaa
     3961 tattatttta cctgctttaa ttggtgtcat tgtaatacta gttggtaatg ttggcgtctt
     4021 ttttatttgc agtatattgc tatttttagg atttattttt aatgcacttt taaaatatac
     4081 aaataacaac atgattgata gacactcaaa agaagatttt tctgaaactt gggaattctt
     4141 gaaacaatct aaagaaattc catttatcat aatcatccaa tttgcctgca tattgattaa
     4201 tactggcctt tggcgtgttg cattaccatt gtttatttcc aatatattaa aagagggcgt
     4261 tggtgtatat ggactagcta catcatgttt aggtatagca tctttattaa tgtcattgat
     4321 tatgggttta ctatcagaaa aacgattaat ctttaaattt agtattggtg ttttagtttg
     4381 ggggattggc ttatcgataa ttaatgtgtt tccaagtgtg gcgatactat atataggtgc
     4441 aacattagtg ggacttggac aatctataga gggactaaca agatcagttg ccattcaaat
     4501 aaaaacgcca aatcatttga tggggaaagt atttagtatc tcatctacat cgaattacgc
     4561 agcggataca ttatcttagg actgataagt ttaattatac ctttactaag cttaagtaat
     4621 atatttatat caggaggtgc aattatttca atgcttagct tagctgggtt aaagtttgtt
     4681 aagaagtcta tgcaaacaaa atagaatttt aatcaatgct attaaggtgg gaattgaaat
     4741 gaaatataaa attagtttgg cttataattt agcaattata atagggtcgc taattatatt
     4801 atgtatacta atatctagag gttatgatat atatgtaatc ttgattccaa ttttgactat
     4861 tttagctagt ttaatcaatt taatttgtga tattaaaaag cataaatgat tctatattaa
     4921 tgcaactttg tattcgtaca aggttgtatt tttttcgcaa acaattactt aatgacagcg
     4981 catcaataaa tctaaccaac acactatcgc aaacatttat ggatattttg tgattttata
     5041 aaagcaaacg tagaataatg cgataagtaa taatgctatc gttaaaaata agaatgacaa
     5101 tgcaataaaa tcatattcaa agcatagaat tgaagacatt aaaaatactg cactcaaact
     5161 gatacatagc gtaaatatat atgcaatttg gttcttgtgt ttatctgcaa tggtcgtttg
     5221 atttatataa gaaattagtg tgaaatcttt agttattgcg acataaatgc ctaatataac
     5281 catacttatg cagaatacga tactaaatac gatgttgacg gtcattgttg caccttcctg
     5341 atagaatata atgtactgtc ttttagtaat gaatgcgtat cttatatatg tatgtttcta
     5401 aaaaacagta cgtttttatc aatttttaat ttattagttg aatgaatggg gttatgaaaa
     5461 aggaagtttt aatcttttgt catgaaataa atgggatgaa tatcacgact agaagtaatg
     5521 ttacgaacag gagcgtataa atctagagac gctaaattcg acatagtatg ttgctcaatt
     5581 atggctgatg atgagtttaa agtatgtgcg ttggaactgt cggatttttg ttcataatgt
     5641 tttgcatatt gtgccatgat gaatagtgta aaaataaata aaacaataag agatataatg
     5701 cccataatca aaagtatttg tttagagcct ttcattattt cacatccttt ctaaaatata
     5761 tttgtaacta aatttaaaat agttattttt gtaattctaa acctttttca tcgcgaaaac
     5821 aatt
//
LOCUS       DAPDIM010000107         5682 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000107 DAPDIM010000000
VERSION     DAPDIM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5682
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.109"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            38..766
                     /locus_tag="RFE25_002650"
     CDS             38..766
                     /locus_tag="RFE25_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5067 domain-containing protein"
                     /protein_id="HDU2817668.1"
                     /translation="MKKVMGILLASTLILGACGHHQDSAKKESASHKKKENDNEELNE
                     ELKEFKSKKNMDIKIKGDTIVSDKFEAKIKEPFIINEKDEKKKYIAFKMEITAKKDDK
                     DLNPSSISHDYINITQDDKNTVNKLRDGYLLSDKKYKDWTEHNQDQIKKGKTAQAMFI
                     YELRGDGNINLNVHKYSEDKTVDSKSFKFSKLKTEDFSHRAETREEVEKKEKEFEEEY
                     KKEQEREKEKEKQKDDDHSSLDEV"
     gene            857..1104
                     /locus_tag="RFE25_002651"
                     /pseudo
     CDS             857..1104
                     /locus_tag="RFE25_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728980.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1120..1443
                     /locus_tag="RFE25_002652"
     CDS             1120..1443
                     /locus_tag="RFE25_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817669.1"
                     /translation="MNNEELEMRLLLMKQSIEQLQEELAPNLKTRDLVLLRYMYSYKE
                     INMLDSYLFQLATNKEQITKKQFKTKLENIREVPEIPIRQVNDILEGYKNSELYVELI
                     NSILK"
     gene            complement(2508..3356)
                     /locus_tag="RFE25_002653"
     CDS             complement(2508..3356)
                     /locus_tag="RFE25_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDU2817670.1"
                     /translation="MKRLDGIPESMLIPLIARAKEYEYEKPIIKDALSKKIFDGLDDI
                     YKNVTCDDMSQIGISIRSVIIDSVTKRLIKDNKNLIVINIGCGLDTRFQRFNNEKISW
                     IDLDVPESIEIRKTFFKETDSYKMIAKSMLDYSWIEDVINYKFFNSKSNILFIFEGVL
                     MYFDESVMTKLLHTIIKKFGDHNLTFAIEFCSKTIANNTKRHKSVSKLSSQPVFKYGY
                     NDLNELDKVLPNKMKVINEYNYFDYHKKRWGLFGYCRYIPYLKKRLNNKIVIMEYKPA
                     KLITHN"
     gene            complement(3414..4328)
                     /locus_tag="RFE25_002654"
     CDS             complement(3414..4328)
                     /locus_tag="RFE25_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDU2817671.1"
                     /translation="MKRLIGILLCSLFILTACSTSVDKTSDSTKTIDYKIENGKTLKV
                     PEKPKRVAVLTGFYVGDFIKLGIKPIAVSDITKDSSILKPYLKGVDYIGENDVEKVAK
                     AKPDLIVVDAMDKNIKKYQKIAPTVPYTYNKYNHKEILKEIGNLTNNEDKAKKWIEEW
                     EDKTRKDKKEIQSKIGQATASVFEPDEKQIYIYNSTWGRGLDIVHDAFGMPMTKQYKD
                     KLQEDKKGYASISKENISKYAGDYIFLSKPSYGKFDFEKTHTWQNIEAVKKGHVISYK
                     AEDYWFTDPITLEHLRSKLKKEILNKSH"
     gene            complement(5254..>5682)
                     /locus_tag="RFE25_002655"
     CDS             complement(5254..>5682)
                     /locus_tag="RFE25_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817672.1"
                     /translation="RHFNIKKDINILKTDTTQLYLHSSDKNEIALVGGTFNEIYFLNE
                     FIEVQLMKHYKKEKINNRKMSKDIQRALLSSEDVLKIMNKLDSMLVNKINILYSDNEG
                     DGTMTFVTGTEYFKWYFPEYPDKIKTLKIEDVKKHTFTDK"
BASE COUNT         2040 a          835 c          747 g         2060 t
ORIGIN      
        1 taaaataaat ttttgcgaaa taaaggagac atgttaaatg aaaaaagtaa tggggatatt
       61 attagcaagt acacttatct taggtgcttg tggacatcat caagatagtg caaaaaaaga
      121 gagcgctagt cacaaaaaga aagaaaatga caatgaagaa ttaaatgaag aacttaaaga
      181 atttaaaagc aaaaaaaata tggatataaa aattaaaggc gatactattg ttagtgacaa
      241 atttgaagct aaaataaaag aaccgtttat catcaatgaa aaagatgaga aaaagaaata
      301 tatcgctttt aaaatggaaa ttactgctaa aaaagacgat aaagatttaa atccatcttc
      361 tatttctcat gactatatta atatcactca agatgataaa aatacagtaa ataaattaag
      421 agatggttat cttttaagtg ataaaaaata taaagattgg acagaacata accaagatca
      481 aattaaaaaa ggcaaaactg cacaagccat gtttatctat gagttaagag gtgatggaaa
      541 tattaattta aatgtccata aatactcaga agataaaaca gttgattcta aatcattcaa
      601 atttagtaaa cttaaaaccg aagatttttc tcatagagcg gaaacaagag aagaagtaga
      661 aaagaaagaa aaagaatttg aagaagagta caaaaaagaa caagaacgag agaaagaaaa
      721 agaaaagcaa aaagatgacg accacagtag tttagatgaa gtataaattt ggtttgttga
      781 ttgtcttaca ttcagttatt taatttttag agaaactgac ttatttatag cttagccaac
      841 atgatactat aaaactatga ttaaaaataa aaaatctgtg tttaatggtg ttaaagaaat
      901 cagtccccgt gccggaaaat cataaaaaaa agatgggata aatttgtaaa tcccgcattg
      961 aataatgcat taaaacaaga agaggctaca tggggaaatg tacaaggtca agtttcacaa
     1021 gcattgatgg gaactggtat taaagattct actgcaagaa gcatagggtt ttgggtttcc
     1081 caagttggtc aagcattaat ataaaaagag tgtgataaaa tgaataatga agaattagaa
     1141 atgagattgt tattaatgaa acaatcaata gaacaattac aagaagaact agcgcctaac
     1201 ttaaaaacta gagatttagt gttattaaga tatatgtatt catataaaga aattaatatg
     1261 ctagattctt acttgttcca attggctaca aataaagagc aaataacaaa aaaacaattt
     1321 aaaacaaaat tggaaaacat tagagaagta ccagaaatac ctattagaca agttaatgat
     1381 atattagaag gttataaaaa tagtgagtta tatgttgagt tgataaatag catcctaaaa
     1441 taaaaataaa catactaaga ttagctatga aggaatctat gacgatagat tttttcatag
     1501 ctatttttta tagttataaa gaggagtagt ctgttctgac tcttggattt taaatctgta
     1561 taataaacaa gtaagcttta ctctcgcctt ttaaaattcg tttgtagtat gttgggttct
     1621 taaaatcgtg aataggaaaa tgcaatgaga aaggttaagt aaagttttta acttctcatt
     1681 tattcaatgg agaatttttt atcgattact tagacattaa tattagtaaa agaagtagtg
     1741 tagttgcaaa ttataaaaac taaaaattcc aaaaagagtt tatcatccaa aacaataaaa
     1801 atggctacaa tggtatgttg tgaaatgcat ttcttaacta cgacttcttt tatttccgtc
     1861 tcgtcaacta ttgctgattg tgttaatagg catattgatt ctaatgaaaa tatcaaaact
     1921 cggctcatct ctttataact acacccactt agtgacgtaa caaaaatgaa aagttctttt
     1981 tcagtagcca tttatccaat taagtgtaga cgattcacat ttttatattg acatatataa
     2041 catggagaat tttttgcgta taaagaagtt tcttcatgaa caatgttgaa tgtaaaactc
     2101 agaatccaac ttttttgaca cttatttgac acacatcact gtccccttat atctcaaaaa
     2161 ctaattcata atcacttatt actctttcct ccatcaaata aacacctata caaacactgc
     2221 tatatcaata ctcacaacaa attctgcaat gcattatccc ctgaaaaaca cataataaaa
     2281 aagcctacat ccacaaaggt tgtaggctac aaatatggag acggcgggag ttcattaaag
     2341 cgtttatcta ttcatgtata actcgctata agcattgtca tatcaacgtt taaattgact
     2401 aatcagttgt gtgtaaaatg ttaaaattga aaaaacacaa gatatttgtg cactttactt
     2461 ttaataaatt cctatctacg tttttttgaa atattttact ttaatactca attatgagtg
     2521 attaatttag ctggtttata ttccataatt actattttat tgtttagcct ttttttcaga
     2581 taaggtatat atctacaata cccaaagagc ccccaccttt tcttatggta gtcaaagtaa
     2641 ttatattcat ttataacttt cattttattt ggtaaaactt tatccaattc atttaaatca
     2701 ttgtatccat atttaaaaac aggttgtgag gataattttg atacagattt atgtcttttt
     2761 gtattatttg caattgtttt tgagcaaaat tcaatcgcaa atgtcaaatt atgatctcca
     2821 aactttttaa taatagtatg taataattta gtcattacac tctcatcaaa atacatcaat
     2881 acaccttcaa agataaacaa tatatttgac ttactattaa aaaatttata atttataaca
     2941 tcttcaatcc aactgtaatc cagcattgat ttagctatca tcttataact atctgtttct
     3001 ttaaaaaatg tttttcgtat ttctattgat tcaggtacat ctaaatctat ccacgatatt
     3061 ttttcgttat taaatctttg aaaccttgta tctaagccac aacctatatt gatcacaatc
     3121 aaatttttat tatccttgat aagcctttta gtaacactat ctattatcac agaacgtata
     3181 ctaattccaa tttgagacat gtcatcacat gtaacatttt tgtatatatc atctaaacca
     3241 tcaaatattt ttttagatag tgcgtctttt attattggtt tttcgtattc gtactctttt
     3301 gctcgagcta tcaaaggaat taacattgat tcgggaattc catctagtcg tttcatttaa
     3361 tcactccgta aaaatattat tattaataca ttagaaattt ttataactta tttctagtga
     3421 gatttattta aaatttcttt ttttaattta cttctcaaat gttctaatgt aataggatct
     3481 gtgaaccaat aatcttctgc tttatatgaa attacatgtc ctttttttac agcttcaata
     3541 ttctgccatg tatgtgtttt ttcaaaatca aatttcccgt atgaaggctt acttaaaaat
     3601 atataatcac cagcatattt actaatattt tcttttgaaa tcgaagcata acctttttta
     3661 tcttcttgta atttatcttt atattgcttt gtcattggca taccgaatgc atcatgaaca
     3721 atatccaaac cacgacccca tgtagagtta tatatgtata tttgcttttc atctggttca
     3781 aacacagatg ctgttgcttg accaatttta ctttgaattt cttttttatc tttcctagtt
     3841 ttatcttccc actcttcaat ccattttttt gctttatcct cattattagt caaattgcct
     3901 atttctttta atatttcttt atgattgtat ttattatatg tatatgggac tgttggcgct
     3961 attttttggt attttttaat atttttatcc atagcatcta caacgattaa atcgggtttt
     4021 gctttagcaa ctttttcaac atcattttct ccaatataat caaccccttt taaataaggt
     4081 tttaaaattg aagaatcttt agttatatct gaaacagcaa ttggtttgat tcctaacttt
     4141 ataaaatcac caacataaaa tccagttaat acagcaactc ttttaggttt ctctggtact
     4201 ttcagtgttt taccattttc aattttatag tctatagtct ttgtcgagtc acttgtttta
     4261 tcgacagatg ttgaacacgc agtcaaaata aataaactac ataataaaat tccaattaat
     4321 cttttcataa tatcatcctt tcgcttttaa ttgatattca ttttcaatta tagattttta
     4381 aaaataatag tcaatactta tacctatcct actcgatgga atgaatgtat ttcgttaagc
     4441 cataattaac ttatacattg tttttaacgt gtgagagaat ttttattatc acatgaaagc
     4501 tttttgatat agatgtttgt gaataaaaaa ataggcaagt accgaagtac ctgcctgtta
     4561 tctacattta aatcttgaga gaaatgttaa aaagttctag taaaataata gcacatttta
     4621 tctttaaatg taaatagaaa gcaggtgtgt aacgcacctg cttaaataga catgaatatg
     4681 tcattctaac tgatttctcc ccataagtca cctaatacct gattaggtgg ggcagaacca
     4741 ttccatgttc taataggcaa gtaataacgt tgcccctccc gtttatataa tacccataaa
     4801 tagcatttat ataactaatt tatgtaattt tacaaggctc aaaattgagt tcttccgtta
     4861 aattcataaa catttagtac ggcattttag tttcgccgtt tgatgttatg tgttctttgg
     4921 tgcgttctgg ttcgaaaaga gttgcttatt agtataaaat acttgcgccc atatatcaca
     4981 ctggtgggac atttaattct ggattttcag ctattttcat aaatttatta gctgataatt
     5041 agcttaatcc aattttcaag ccatagccta aattccccat gcactaagtc attttgtttc
     5101 atatggtttt aatctacgac caatcgcaaa gatagattga ccagcgatgt ttaaagtcat
     5161 atttcacgga tccacattta cgataaacat atctagttac acaatattat cccttactgc
     5221 aacacaggac gtttctcagc gtataattta tatttattta tctgtaaacg tatgtttttt
     5281 tacatcttct attttcaagg tttttatttt gtctggatat tcaggaaaat accatttaaa
     5341 atattctgtg ccagtaacaa atgtcattgt tccatcacct tcattatctg agtatagtat
     5401 gtttatttta ttaactaaca tagaatctaa tttattcatt attttcaaaa catcttcact
     5461 agataatagt gctctttgta tatctttact catctttcta ttatttattt tttctttttt
     5521 ataatgtttc attaattgaa cttcaataaa ctcatttaaa aagtaaattt cattaaaagt
     5581 accacctact aatgcaattt catttttgtc agatgaatgt aaatacaatt gtgttgtatc
     5641 agtttttaaa atattaatat ctttctttat attaaaatgt ct
//
LOCUS       DAPDIM010000108         5564 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000108 DAPDIM010000000
VERSION     DAPDIM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5564
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.110"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            38..745
                     /gene="splA"
                     /locus_tag="RFE25_002656"
     CDS             38..745
                     /gene="splA"
                     /locus_tag="RFE25_002656"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease SplA"
                     /protein_id="HDU2817673.1"
                     /translation="MNKNVMVKGLTALTILTSLGFAENISNQPHSIAKAEKNVKEITD
                     ATKAPYNSVVAFAGGTGVVVGKNTIVTNKHIAKSNDIFKNRVAAHYSSKGKGGGNYDV
                     KDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFAEGAKAKDRISVIGYPKGAQTK
                     YKMFESTGTINHISGTFIEFDAYAQPCNSGSPVLNSKHELIGILYAGSGKDESEKNFG
                     VYFTPQLKEFIQNNIEK"
     gene            870..1592
                     /gene="splB"
                     /locus_tag="RFE25_002657"
     CDS             870..1592
                     /gene="splB"
                     /locus_tag="RFE25_002657"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease SplB"
                     /protein_id="HDU2817674.1"
                     /translation="MNKNVVIKSLATLTILTSVTGIGTTLVEEVQQTAKAENNVTKIQ
                     DTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSI
                     KKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHP
                     YKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDN
                     RNAYGVYFTPEIKKFIAENIDK"
     gene            1650..2369
                     /gene="splC"
                     /locus_tag="RFE25_002658"
     CDS             1650..2369
                     /gene="splC"
                     /locus_tag="RFE25_002658"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease SplC"
                     /protein_id="HDU2817675.1"
                     /translation="MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVK
                     DTNNFPYNGVVSFKNATGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKI
                     KSISDYPGDEDISVMNIEEQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLP
                     AQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSE
                     YNGAVYFTPQIKDFIQKHIEQ"
     gene            2490..3209
                     /gene="splD"
                     /locus_tag="RFE25_002659"
     CDS             2490..3209
                     /gene="splD"
                     /locus_tag="RFE25_002659"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease SplD"
                     /protein_id="HDU2817676.1"
                     /translation="MNKNIIIKSIAALTILTSITGVGTTVVDGIQQTAKAENSVKLIT
                     NTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYK
                     VTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPN
                     GNKLQMYESTGKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGEST
                     RSFAVYFSPEIKKFIADNLDK"
     gene            complement(3158..3265)
                     /locus_tag="RFE25_002660"
     CDS             complement(3158..3265)
                     /locus_tag="RFE25_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817677.1"
                     /translation="MLILLLISKNHLSMYGWMIYLSKLSAINFLISGEK"
     gene            3367..4086
                     /gene="splF"
                     /locus_tag="RFE25_002661"
     CDS             3367..4086
                     /gene="splF"
                     /locus_tag="RFE25_002661"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease SplF"
                     /protein_id="HDU2817678.1"
                     /translation="MNKNIIIKSIAALTILTSVTGVGTTMVEGIQQTAKAENTVKQIT
                     NTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYK
                     VTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPN
                     GNKLQMYESTGKVLSVNGNIVSSDAIIQPGSSGSPILNSKHEAIGVIYAGNKPSGEST
                     RGFAVYFSPEIKKFIADNLDK"
     gene            4149..4283
                     /locus_tag="RFE25_002662"
     CDS             4149..4283
                     /locus_tag="RFE25_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817679.1"
                     /translation="MHYLICIKANQRLIFTNSIVDWFYLCMNEQLFDIIKNINDFESI
                     "
     gene            4447..>5564
                     /locus_tag="RFE25_002663"
     CDS             4447..>5564
                     /locus_tag="RFE25_002663"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDU2817680.1"
                     /translation="MSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFY
                     RFLSEKAEQEYADALSGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIR
                     EIETQDFDIEHLATAIRKVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALIS
                     KVMVNLDDLPFVHSDMEIDMLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVT
                     DGKDKLRHVYDPTCGSGSLLLRVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYEN
                     FEIRNDDTLENPAFLGNTFDAVIANPPYSAKWTADSKFENDERFSGYGKLAPKSKADF
                     AFIQHMVHYLDDEGTMAVVLPHGVLFRGAAEGVIRRYL"
BASE COUNT         2116 a          847 c         1016 g         1585 t
ORIGIN      
        1 cattaactat aaaaataaat ttggaaggag gtaaaatatg aataaaaatg taatggttaa
       61 aggtttaact gctttaacta ttttaacatc tcttggtttc gctgaaaata tttctaatca
      121 gcctcattca attgccaaag cagaaaagaa tgtcaaagaa attaccgatg caactaaggc
      181 accatacaat tcagtggtag catttgcggg tggtactggt gtagttgttg gtaaaaatac
      241 aatcgtaact aacaaacata tcgctaaaag taatgatatt tttaaaaata gagtagcagc
      301 acattattcg agtaaaggta aaggcggagg aaactacgac gttaaagaca ttgtagaata
      361 tcctggaaaa gaagaccttg cgatagttca tgttcatgaa acaagtacag aaggtttgaa
      421 ttttaataag aacgttagtt atacaaaatt tgcagaagga gcaaaagcga aagatagaat
      481 ttctgttatt ggttatccaa agggtgcaca aacaaaatat aaaatgtttg aatcgacagg
      541 aacgattaac catatcagtg gaacgtttat agaatttgat gcgtatgcac aaccatgtaa
      601 ttcaggatct cctgtattga attctaaaca tgaactgatt ggtattttat atgcaggtag
      661 tggaaaagat gaatctgaaa agaatttcgg tgtttatttc acaccacaat taaaagaatt
      721 tattcaaaat aatattgaaa aataagtatc atcaattcat tcgtgaagtt gattttttaa
      781 agagtgatta agaaaacggt tacataacca actaaatata ctgaattatg tatctagata
      841 tcaaaataat taaaaaagag gaacttaaaa tgaacaaaaa cgtagtcatc aagagtttag
      901 caactttaac aattttaaca tctgtaacag gtattggaac aacattggtt gaggaagttc
      961 aacaaactgc caaagcagaa aataatgtca caaaaattca agatactaat atttttccat
     1021 atactggtgt agttgctttt aaaagtgcaa ctggatttgt agttggaaag aatactattt
     1081 taacaaataa acatgtgtcg aaaaattaca aagtgggcga tcgtattact gcacatccaa
     1141 atagtgataa aggtaatggt ggtatttatt cgattaaaaa gattattaat tatccaggta
     1201 aagaagatgt atcagtcatt caagttgaag agcgtgcaat agaacgtgga ccaaaaggct
     1261 ttaattttaa tgataatgta acgccattca aatatgcggc aggggctaaa gctggtgagc
     1321 gaattaaagt gattggttat ccacacccat acaaaaataa atatgtttta tatgagtcaa
     1381 ctggccctgt gatgtcagta gaaggtagca gtattgtata ttcagcgcat actgaaagcg
     1441 gaaactctgg atcacctgta ttaaacagca acaacgaatt agttggtatt cattttgctt
     1501 ctgatgtaaa aaatgatgat aacagaaatg catatggcgt ctactttaca ccagaaatta
     1561 aaaaattcat tgcagaaaac atagataaat aaacaaattg actttaaacg agcgttgcaa
     1621 catatctcga attgtaaagg agcttgaaaa tgaataaaaa tatagtcatt aaaagcatgg
     1681 cagcattagc cattctaacc tcagtaactg gaataaatgc tgcagtcgtt gaagagacac
     1741 aacaaatagc aaatgcagag aagaatgtta cgcaagttaa agatacaaat aattttccat
     1801 ataatggcgt cgtttcattt aagaatgcga caggttttgt aattggaaaa aatacaatta
     1861 tcaccaataa acatgtatca aaagattata aagttggcga tagaattact gcccatccaa
     1921 acggtgacaa aggaaatggt ggtatatata aaattaaaag catttctgat tatccgggtg
     1981 atgaagacat ctctgtcatg aatattgaag aacaagcagt tgaacgtgga ccaaaaggct
     2041 ttaattttaa tgaaaatgtc caagcattca attttgcgaa agatgctaaa gttgatgaca
     2101 aaattaaagt tattggttac ccattacctg ctcaaaatag ttttaaacag tttgaatcta
     2161 caggaactat aaaaagaatc aaagacaata ttttaaattt tgatgcatac attgaacccg
     2221 ggaattcagg atcaccagtt ctaaattcta acaatgaggt cataggtgtg gtgtatggcg
     2281 gtattggaaa aattggttct gaatataatg gtgccgtata ctttacgcct caaatcaaag
     2341 attttattca aaagcacatt gaacaataaa caaatttaaa tatacaccat gagcatgtgt
     2401 tcaataattt taatgaaaaa catcggtcga atataacata aaaaaacgtc tatatcaaaa
     2461 gcatcatgaa taaacagagg agcacaaaaa tgaataaaaa tataatcatc aaaagtattg
     2521 cggcattgac gattttaaca tcaataactg gtgtcggcac aacagtggtt gatggtattc
     2581 aacaaacagc caaagcagaa aatagtgtga aattaattac caacacgaat gttgcaccat
     2641 acagtggtgt tacatggatg ggcgctggaa caggatttgt agttgggaat catacaataa
     2701 ttaccaataa acatgttact tatcacatga aagtcggtga tgaaatcaaa gcacatccta
     2761 atggttttta taataacggt ggtggacttt ataaagttac taagattgta gattatcctg
     2821 gtaaagaaga tattgcggtt gtacaagttg aagaaaaatc aacgcaacca aaaggtagaa
     2881 aattcaaaga tttcactagc aaatttaata tagcatcaga agctaaagaa aatgaaccta
     2941 tatcagtcat tggttatcca aatcctaatg gaaataaact acaaatgtat gaatcaactg
     3001 gtaaagtact atcagtgaat ggaaatatag tgacatctga tgcggttgtc caacctggca
     3061 gctctggttc acctatatta aatagtaagc gagaagcaat tggtgttatg tatgctagtg
     3121 ataaaccaac aggtgaaagt acaaggtcat ttgctgttta tttctctcct gaaattaaga
     3181 aatttattgc agataattta gataaataaa tcatccatcc atacattgat aaatgatttt
     3241 tagaaattaa caacaaaatc aacaatttta aacatctctg tgattctatt tattcgaaat
     3301 gatttaaaaa ataaaacttc aaaaacctaa ccttatattt atacgaatac ttagaggagc
     3361 acaaaaatga ataaaaatat aatcatcaaa agtattgcag cattgacgat tttaacatca
     3421 gtgactggcg tcggcacaac aatggttgaa ggtattcaac aaacagccaa agccgaaaat
     3481 actgttaaac aaattacaaa tacaaatgtt gcaccataca gtggtgttac atggatgggc
     3541 gctggaacag gatttgtagt tggaaatcat acaatcatta ccaataaaca tgttacctat
     3601 cacatgaaag tcggtgatga aatcaaagca catcctaatg gtttttataa taacggtggt
     3661 ggactttata aagttactaa gattgtagat tatcctggta aagaagatat tgcggttgta
     3721 caagttgaag aaaaatcaac acaaccaaaa ggtagaaaat tcaaagattt cactagtaaa
     3781 tttaatatag catcagaagc taaagaaaat gaacctatat cagtcattgg ttatccaaat
     3841 cctaatggaa ataaactaca aatgtatgaa tcaactggta aagtattatc agtgaatggg
     3901 aatatagtgt catcggatgc aattattcag cctggtagct ctggttcacc tatattaaat
     3961 agtaaacacg aagctattgg tgtaatctat gccggtaata agccatcagg tgaaagcaca
     4021 agaggatttg ctgtttattt ctctcctgaa attaagaaat tcattgcaga taatttagat
     4081 aaataattaa aacttagaca ttcacccaat cctgacaaaa tatactataa ctaacattta
     4141 ttaatatatt gcattattta atatgcatca aagccaatca acgattgatt ttcaccaact
     4201 caattgttga ttggttttat ttatgtatga atgaacaact ttttgacatc attaagaata
     4261 taaatgattt tgaaagcatt tgaaagctac aacatttcta taaaattttt caataacaat
     4321 tgcgccacta aaactcaaaa tttccaccac caacatccaa attatcaaca tcgcaacata
     4381 accaaatgtt ataataaatc tattacacaa agagataaat tacttatgca aaggcggagg
     4441 aatcacatgt ctattactga aaaacaacgt cagcaacaag ctgaattaca taaaaaatta
     4501 tggtcgattg cgaatgattt aagagggaac atggatgcga gtgaattccg taattacatt
     4561 ttaggcttga ttttctatcg cttcttatct gaaaaagccg aacaagaata tgcagatgcc
     4621 ttgtcaggtg aagacatcac gtatcaagaa gcatgggcag atgaagaata tcgtgaagac
     4681 ttaaaagcag aattaattga tcaagtcggt tacttcattg agccacaaga tttattcagt
     4741 gcgatgattc gtgaaattga aacgcaagat ttcgatatag aacatctagc gacggcgatt
     4801 cgcaaagttg aaacatctac attaggtgaa gaaagtgaaa atgactttat cgggctgttc
     4861 agcgatatgg atttgagttc aacgcgacta ggtaacaatg tcaaagaacg tactgcttta
     4921 atctctaaag tcatggttaa tcttgacgac ttaccattcg ttcacagtga catggaaatt
     4981 gatatgttag gtgatgcata tgaattccta atcgggcgct ttgcggcgac agcgggtaaa
     5041 aaagcaggcg agttctatac accacaacaa gtatctaaga tactggcgaa gattgtcaca
     5101 gacggtaaag ataaattacg tcacgtgtac gacccaacat gtggttccgg ttcattgttg
     5161 ttacgtgttg gtaaagaaac gcaagtgtat cgttatttcg gacaagaacg taacaatact
     5221 acatacaact tagcacgcat gaatatgtta ttacatgatg tgcgttatga gaacttcgag
     5281 atccgtaatg atgacacatt ggaaaatcca gcctttttag gcaatacatt tgatgcggtt
     5341 attgcgaacc caccatacag tgcgaaatgg acagcagatt caaaatttga aaatgatgaa
     5401 cgattcagtg gttacggcaa gcttgcgcca aaatccaaag cagactttgc ctttattcaa
     5461 cacatggtac attacctaga cgatgaaggt accatggcag tcgtactccc acatggtgta
     5521 ttattccgtg gtgccgcaga aggtgtgatt cgtcgctatt taat
//
LOCUS       DAPDIM010000109         5515 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000109 DAPDIM010000000
VERSION     DAPDIM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5515
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.111"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            45..626
                     /locus_tag="RFE25_002664"
     CDS             45..626
                     /locus_tag="RFE25_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016170789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4888 domain-containing protein"
                     /protein_id="HDU2817681.1"
                     /translation="MNTKFLGKTLVASALVLTTLGTGLHSSYLGLNTNKVVKTAKAEE
                     KMTNGQLWKKVKDSLIDSNIISGNENEEITVTYVNKTGYSSSVSAYGNNNDDFSSTPS
                     NFSKLKEIDLKKDNVPSDDFNTTVSGEDSWKTLTSKLKEKGLVTDGQTVTIHCNDKSD
                     NTKSSVSGKVGADLTSGNGTTFKKRFIDKITID"
     gene            complement(1099..1387)
                     /locus_tag="RFE25_002665"
                     /pseudo
     CDS             complement(1099..1387)
                     /locus_tag="RFE25_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BsaG protein"
     gene            1573..2046
                     /locus_tag="RFE25_002666"
     CDS             1573..2046
                     /locus_tag="RFE25_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817682.1"
                     /translation="MHLKLNDEDLNYLVNLSKEILEQYNIKLDETCKGDINITSCNSE
                     YFFTLSYFLKPGKATINFRECRYNYSLLRLNLNDGFHKNSNNEKIRGNRINIFSEKEF
                     IQKADGATHMKAYPLPYNIFDDSSDFVKQLFTLLEYTKTNHNDNIKIETNLFMSW"
     gene            2051..2842
                     /locus_tag="RFE25_002667"
     CDS             2051..2842
                     /locus_tag="RFE25_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HDU2817683.1"
                     /translation="MHDNTIKSISKDYFDYLQTESKFIPLENETIEFYSPIVDYFGDS
                     ISVNISFSGDRYKLTDHGETLWNMEQLGIDLTSNKKQKKYQLLNNIVQNYSLVIENKH
                     INFYTNRINLSQAIHDYVLAISEISYLGILKKENIKSLFKDEVMQYFLSNRKIYPNIF
                     PEFKVEGKSKLIHSFEAVFPGEATEYVKTIKRIDKNNAKNVLFDWNDVEIHRNKNFDS
                     NARLNIITEQQDDISEAVSTMLSQYNVEVFSFENKKQLEEKFSNV"
     gene            complement(3212..4195)
                     /gene="lukD"
                     /locus_tag="RFE25_002668"
     CDS             complement(3212..4195)
                     /gene="lukD"
                     /locus_tag="RFE25_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component leukocidin LukED subunit D"
                     /protein_id="HDU2817684.1"
                     /translation="MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITL
                     YKTTATSDNDKLNISQILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQF
                     YWGGKYNVSVSSESNDAVNVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNG
                     SKSFSETINYKQESYRTTIDRKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNEL
                     FLGGRQSSSNAGQNFLPTHQMPLLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMD
                     RYTNQWNRLHWIGNNYKNQNTVTFTSTYEVDWQNHTVKLIGTDSKETNPGV"
     gene            complement(4197..5132)
                     /gene="lukE"
                     /locus_tag="RFE25_002669"
     CDS             complement(4197..5132)
                     /gene="lukE"
                     /locus_tag="RFE25_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_114304764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component leukocidin LukED subunit E"
                     /protein_id="HDU2817685.1"
                     /translation="MFKKKMLAATLSVGLIAPLASPIQESRANTNIENIGDGAEVIKR
                     TEDVSSKKWGVTQNVQFDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRM
                     IWPFQYNIGLTTKDPNVSLINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFN
                     YSKTISYTQKSYVSEVDKQNSKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGS
                     AREYFAPDNQLPPLVQSGFNPSFITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRT
                     GIYAERKHNAFVNRNFVVRYEVNWKTHEIKVKGHN"
BASE COUNT         1982 a          856 c          734 g         1943 t
ORIGIN      
        1 ttttcattgt aaacgtttac aatataaaaa aaggagcaat taaaatgaat acaaaatttt
       61 taggtaaaac attagtagca agtgctttag tattaacaac attaggaaca ggtttacatt
      121 cttcatactt aggattaaat acaaataaag ttgttaaaac agcaaaagca gaagaaaaaa
      181 tgacaaatgg tcaattgtgg aaaaaagtta aagattcatt aattgattca aatattatta
      241 gtggtaacga aaatgaagag attacagtaa catatgttaa taaaaccgga tattcttcaa
      301 gtgtttctgc ctatggtaat aataatgacg atttttcaag tactccaagt aatttttcta
      361 aacttaagga aattgacttg aaaaaagata atgtaccgtc agatgatttt aatactactg
      421 ttagtggtga agatagttgg aaaacactta catctaaatt aaaggaaaaa ggtttggtta
      481 cagatggaca aacagtaact attcattgta atgataagtc tgacaataca aaatcatctg
      541 tttcaggtaa agtaggagca gatctgacaa gtggcaatgg aactacattc aaaaaacgct
      601 ttattgataa aatcacaatt gattaaacct taaactcaaa tttccttaat tcataaaacc
      661 ttaataacta accctttctt acaaaccacc tagcccataa tatattaaaa cgtcattttt
      721 atttcaatta gcggaaaata aaaaaaccat tccgcattaa ctttggcaag ttggaatggt
      781 taaaaaatat tttagaagcc agcgtttggc ttgctttgac gacatgttcg cgcatgtcgt
      841 cttattttta catttatata ataacacgca attcaataaa atgtctaatc aataaacctc
      901 aattacattc aaattcaaaa actttgcacc taatattcat cgcttaaata aacattacgt
      961 ttaattaacc agacattgtc aatcgcgtct aatacccctg ctgtccgaat acaaaattat
     1021 tttgtattca tatttatctg ttctctttcc tcccttttaa acgcaactaa atttctttta
     1081 ccattagcgc cccaatcttt aatctttaat tgttctaccg ctccatttat taaatccttt
     1141 aaagagtaaa actgctaata gcaacgtgat aataatatag atcgccaatg ttaatgtaac
     1201 tggtatactc ccttcgataa acatataaac gtaacacgta gcatatgtga ttggtaaata
     1261 gaaccacgaa tgatctccaa gcacttctaa tccaaaataa acgttaaaaa taaacattaa
     1321 aactccgaca acaatagcca ttacatcttt aatgaaaaat atatctaaca ttatcacaaa
     1381 ttattaataa tgttaaaaat gacggtacta aataaattaa taaatattcc attgtcatgt
     1441 attgctaaac gattatgacg ctaaaaagga ataattatta agtttataga aaacatctgt
     1501 ataacttact acaaatactg aaaataatat aaggatttaa gatcgtaaaa tctaaactaa
     1561 ggagatgttt aaatgcattt gaaactgaac gatgaagatt taaattattt agtaaatcta
     1621 agtaaagaaa tacttgaaca atacaacatt aaattagacg aaacttgtaa gggagatatt
     1681 aacataacat catgtaattc tgaatacttt ttcactttaa gctatttttt aaagcctgga
     1741 aaagcaacta taaatttcag agaatgccgt tacaactata gcttgttacg tttaaatctt
     1801 aatgacggtt ttcataaaaa ctctaataat gagaaaataa ggggaaatag aattaatata
     1861 ttttctgaaa aagaatttat acaaaaagct gacggcgcaa cccatatgaa agcatatcct
     1921 ttaccttata atatatttga cgatagctct gattttgtaa aacaattatt tactttgctt
     1981 gaatatacaa aaactaatca taatgataat attaaaattg aaactaatct attcatgagt
     2041 tggtgatact atgcatgaca acacaattaa atctattagc aaagactatt ttgattactt
     2101 acaaacagaa tcaaagttta tcccattaga aaatgaaact atagaatttt attcacctat
     2161 cgtcgattat tttggtgatt ctatttctgt aaatatatct ttttcagggg atcgatataa
     2221 actaactgat catggtgaaa ctttatggaa catggaacaa ttaggtatag atttaactag
     2281 taataaaaaa caaaaaaagt atcaacttct caataatatt gtacaaaact acagtctagt
     2341 catcgaaaat aagcacataa acttttatac aaatagaata aacttatctc aagctattca
     2401 tgattatgtt ttggctattt ccgagatcag ttatttggga atattaaaga aagaaaatat
     2461 taagtcctta tttaaagacg aagtgatgca atattttcta tcaaacagaa agatttatcc
     2521 taatatattt cccgaattta aggtagaggg gaaatctaag ttaatccata gtttcgaagc
     2581 agtatttcca ggagaagcta cagagtatgt taaaacaatt aaacgaatcg ataaaaacaa
     2641 tgcaaaaaat gtccttttcg attggaatga tgttgaaata catagaaata aaaattttga
     2701 ttctaatgct agacttaata tcattacaga acaacaagat gatattagcg aagcagtatc
     2761 aacaatgttg tctcaatata atgtagaggt attttcattt gaaaacaaaa aacaacttga
     2821 agaaaagttt agtaacgtat aattatcgtg ttatataatg tttcttcgat aatagtttct
     2881 atttcaatta aatcaccgat acttaaaatg ataaatttac caataccaag tttgtaatga
     2941 actttcaccg tcatacaatc atagatgcta tatctacaaa acgaaccacg ccgattaaga
     3001 cgtggttcca tttttttaat aattttttat atgttggaag tttctaaata attctacttt
     3061 cgtaaattta gcaccctgct atttagcaaa gtaatctaca tttccctaac taaaaattat
     3121 catgtgtgta aataaaaatt atgttagttc tttaattccg tttgataatt gaaataattg
     3181 cactttgttg attatttaat catatacaat tctatactcc aggattagtt tctttagaat
     3241 ccgtaccgat taatttaaca gtatggtttt gccagtcaac ttcataagta gatgtaaacg
     3301 ttactgtatt ttgatttttg tagttattac caatccagtg tagtcgattc cattgattag
     3361 tatatctatc catttctctt tggtaagtta ctttgatttt agattttttt gtatcatttt
     3421 gtttatgaga aagtacgctt ataaattctg ggttaaagtt accacgcgcc aataaaggca
     3481 tttgatgtgt tggcaagaaa ttttgtccag catttgaact actttgtcta ccacctaaaa
     3541 acagttcatt accatatgtt gggtcataac tatctctacc atatggtccc caaccattat
     3601 tcataatttt gtgcgcctca acaccccagc caattgattt atgatttgtt tttctatcaa
     3661 tcgtagttct gtaactttct tgtttataat ttattgtttc tgaaaatgat tttgatccat
     3721 tcaatccacc tgataagcca ttagatatat taatatctcc gccataagaa taacctaatg
     3781 tttgttgaac ttggaattct tcattttgat ttttaggtgc atagtcaaca acatttacag
     3841 catcatttga ttctgaacta accgaaacat tatacttacc gccccaataa aactgtgagt
     3901 aattgtaatc ttttggatta ggctttttat aacctgaatt aatgtttccg gctgccttaa
     3961 gtactaatgt atctttgtca taacttttat ccttaatgaa attaaacgtt aaaatttgag
     4021 aaatattcaa tttatcatta tcagatgttg ctgttgtttt gtataaagtg attttgtcat
     4081 ctactttttt ctcgcttaca ggtgtgatat gttgagctgc atcaactgta ttcgatagca
     4141 aaagcagtgc aattgatgaa gcaactgatg atttgactaa ttttttcatt ttcatattaa
     4201 ttatgtcctt tcactttaat ttcgtgtgtt ttccaattaa cttcatatct aactacaaag
     4261 tttctattta caaatgcatt atgctttctt tctgcgtaaa taccagttct agggaataaa
     4321 gtcgcatatg taatatctaa gtttctacca tatgaaattt caaattcact cgtatcactt
     4381 gaaccttttt catgtgatag tgtagtgata aatgatggat taaagccact ttgaactaaa
     4441 ggtggcaatt gattatcagg agcaaaatat tctcttgctg aacctgttgg accatttgga
     4501 ctttgtacga ataaatatct atcatgcgca gattttttac catcaggcgt aacaaattcg
     4561 tttgctttaa caccccattt aactgatttt gagttttgct tgtctacttc actgacataa
     4621 ctcttttggg tataactaat tgttttagaa taattaaatg agccattgcc acctatagat
     4681 ggtgctgact ggaaattacc tccaatgtta tatcctaatg tttgaccaac atcagtagtt
     4741 tctattttgt ttttaggaag gtaattgatt aagctaacat ttggatcttt agtcgtcagt
     4801 cctatattat attggaatgg ccaaatcatt cgtttagtca attcatatcc actacccttc
     4861 acatctgaaa atgaagttct ggaattaata aaaccttgca ttttaacaat taaagcatct
     4921 ttgttatatt ttttatcttt tacaaagtcg aattgaacat tttgagtaac gccccatttc
     4981 ttactactta catcctccgt acgtttgatt acttcagcac catcaccaat attctctata
     5041 ttagtattag ctctagattc ttgaatcgga gatgctaaag gcgcaatcag tcctactgac
     5101 aaagttgcag ctaacatttt tttcttaaac ataagtttca ctttctttct atataaattt
     5161 ttaatacaaa tttattatag attatttcac ttatttataa aattaactgt tcattaaaaa
     5221 aataaaatgc tataaaatat taaaaatgat acaatttatt catttatgat gctgaaaacc
     5281 ggtcattttg gcgcaacctt cattacattt aaatagttcc ctttatactc gaacaatatg
     5341 ataaaattgc cgatgctcaa ctttttcgct ataaaaatca aaacgaactt taatcaaatc
     5401 ttaaaaaata atgtttgtat tatcaaaaat aatctataat tgaatttaaa attaactgat
     5461 tattaactat tgtccgttaa acggagagga ttacttcgta tactgttata actga
//
LOCUS       DAPDIM010000110         5417 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000110 DAPDIM010000000
VERSION     DAPDIM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5417
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.112"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            145..1263
                     /gene="ald"
                     /locus_tag="RFE25_002670"
     CDS             145..1263
                     /gene="ald"
                     /locus_tag="RFE25_002670"
                     /EC_number="1.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HDU2817686.1"
                     /translation="MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSG
                     FSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIV
                     EKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
                     HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTV
                     VKSTPENLAEQIKKADVFISTILIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTI
                     ETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNIDYILEICDKGLEQAI
                     KDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE"
     gene            1358..2398
                     /gene="tdcB"
                     /locus_tag="RFE25_002671"
     CDS             1358..2398
                     /gene="tdcB"
                     /locus_tag="RFE25_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HDU2817687.1"
                     /translation="MTTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQN
                     ITKGNVYLKLENMQFTGSFKFRGASNKINHLSDEQKAKGIIGASAGNHAQGVALTAKL
                     LGIDATIVMPETAPIAKQNATKGYGAKVILKGKNFNETRLYMEELAKENGMTIVHPYD
                     DKFVMAGQGTIGLEILDDIWNVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQAEN
                     VHGMAESFYKRALTEHREDSTIADGCDVKVPGEKTYEVVKHLVDEFILVSEEEIEHAM
                     QDLMQRAKIITEGAGALPTAAILSGKIDKKWLEGKNVVALVSGGNVDLTRVSGVIEHG
                     LNIADTSKGVVG"
     gene            2429..3751
                     /locus_tag="RFE25_002672"
     CDS             2429..3751
                     /locus_tag="RFE25_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDU2817688.1"
                     /translation="MSNGKELQKNIGFFSAFAIVMGTVIGSGVFFKISNVTEVTGTAG
                     MALFVWFLGGIITICAGLTAAELAAAIPETGGLTKYIEYTYGDFWGFLSGWAQSFIYF
                     PANVAALSIVFATQLINLFHLSIGSLIPIAIASALSIVLINFLGSKAGGILQSVTLVI
                     KLIPIIVIVIFGIFQSGDITFSLIPTTGNSGNGFFTAIGSGLLATMFAYDGWIHVGNV
                     AGELKNPKRDLPLAISVGIGCIMAVYLLINATFLLTLPIELLAGNLNAASDTSKILFG
                     ENGGKIITIGILISVYGTINGYTMTGMRVPYAMAERKLLPFSHLFAKLTKSGAPWFGA
                     IIQLIIAIIMMSMGAFDTITNMLIFVIWLFYCMSFVAVIILRKREPNMERPYKVPLYP
                     IIPLIAILAGSFVLINTLFTQFILAIIGILITALGIPVYYYKKKQKAA"
     gene            3907..5298
                     /gene="norB"
                     /locus_tag="RFE25_002673"
     CDS             3907..5298
                     /gene="norB"
                     /locus_tag="RFE25_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter NorB"
                     /protein_id="HDU2817689.1"
                     /translation="MEKPSREAFEGNNKLLIGIVLSVITFWLFAQSLVNVVPILEDSF
                     NTDIGTVNIAVSITALFSGMFVVGAGGLADKYGRIKLTNIGIILNILGSLLIIISNIP
                     LLLIIGRLIQGLSAACIMPATLSIIKSYYIGKDRQRALSYWSIGSWGGSGVCSFFGGA
                     VATLLGWRWIFILSIIISLIALFLIKGTPETKSKSISLNKFDIKGLVLLVIMLLTLNI
                     LITKGSELGVTSLLFITLLAIAIGSFSLFIVLEKRATNPLIDFKLFKNKAYTGATASN
                     FLLNGVAGTLIVANTFVQRGLGYSSLQAGSLSITYLVMVLIMIRVGEKLLQTLGCKKP
                     MLIGTGVLIVGECLISLTFLPEILYVICCIIGYLFFGLGLGIYATPSTDTAIANAPLE
                     KVGVAAGIYKMASALGGAFGVALSGAVYAIVSNMTNIYTGAMIALWLNAGMGILSFVI
                     ILLLVPKQNDTQL"
BASE COUNT         1885 a          765 c         1030 g         1737 t
ORIGIN      
        1 atttaagaat aagaataata tattaaatat ttattaacaa attatagata aaatatgaat
       61 aattaattaa tggtatttac atattcataa ccaaaggata aaataattgt gaaattattc
      121 acaaatgaaa gaggagtgtt gcaaatgtta gttgcagtag tcaaagaatt aaaacaaggt
      181 gaaggacgtg tagcttgcac acccgaaaat gtgcgtaagt taacggatgc aggacataaa
      241 gtaattgttg aaaaaaatgc tggcattggt tcaggatttt ctaacgatat gtatgaaaaa
      301 gaaggcgcta agatcgtaac tcacgaacaa gcatgggaag ctgatcttgt tatcaaagta
      361 aaagaacctc atgaaagcga atatcaatat ttcaaaaaga atcaaattat ctggggattt
      421 ttacatctag catcttcaaa agaaatagta gaaaaaatgc aagaagttgg tgtaactgcg
      481 attagtggtg aaaccattat aaaaaatgga aaagcagaat tattagcgcc aatgagtgct
      541 atagcaggtc aacgctcagc aattatggga gcttactact ctgaagcaca acatggtggt
      601 caaggtactt tagtgactgg tgtacatgaa aatgtggata tacctggtag tacatatgtg
      661 attttcggtg gtggcgtagc agcaacaaat gcagcaaatg ttgccttggg actaaatgct
      721 aaagtaatca ttatcgagtt aaacgatgac cgcattaaat atcttgaaga tatgtatgca
      781 gaaaaagatg tcacagtagt caaatcaaca ccagaaaatt tagcagaaca aattaagaaa
      841 gcagatgtat ttatttctac aattttaatt ccaggtgcga aaccgccaaa attggttact
      901 cgtgagatgg ttaaatcaat gaaaaaaggt tcagtattaa tcgatatagc tattgaccaa
      961 ggtggaacta ttgaaacaat tagaccaact acaatttctg atccagtgta tgaagaagaa
     1021 ggtgtgattc attatggtgt accaaatcaa ccaggagcag tcccaagaac ttcaacaatg
     1081 gcattagcac aaggaaatat tgattatata ttagaaattt gtgacaaagg cttagaacaa
     1141 gcaattaaag ataatgaagc cttaagtact ggtgtaaaca tttaccaagg acaagtgaca
     1201 aatcaaggat tagcttcatc acatgaccta gattataaag aaatattaaa tgttatcgaa
     1261 tagataataa tttaaatgaa attgagtgaa atgaatattt taaatatagc attatagttt
     1321 ggactaaaaa tttacaaaac ggaaggatgt aattattatg acaaccaaca cagttacatt
     1381 acaaacagca catattgtaa gtttaggaga tatcgaagaa gctaaagcaa gcattaaacc
     1441 atttattcgt cgaacaccac taattaaatc tatgtattta agtcaaaata tcactaaagg
     1501 taacgtatat ttaaaacttg aaaatatgca gtttacaggt tcatttaaat ttagaggtgc
     1561 tagcaataaa attaatcatt tgtcagatga acaaaaagct aaaggtatta ttggcgcatc
     1621 agccggaaat catgcacaag gtgtagcttt gacagcaaaa ctattaggta ttgatgcaac
     1681 gattgtgatg ccagaaacag caccaattgc taaacagaat gctaccaaag gatatggtgc
     1741 aaaagtcatt ttaaaaggta aaaactttaa tgaaactaga ctttatatgg aagaattagc
     1801 gaaagaaaat ggtatgacaa ttgttcatcc atatgatgat aagtttgtca tggctggtca
     1861 aggaacaata ggattagaaa ttttagatga tatatggaat gttaatacgg tcattgttcc
     1921 agttggtgga ggtggcctaa ttgcaggtat tgccaccgct ttaaaatcat tcaacccatc
     1981 aattcatata atcggcgttc aagctgaaaa tgtgcatggc atggcagagt cattctataa
     2041 gagagcttta actgaacatc gtgaagatag cacaattgca gatggttgtg atgtaaaagt
     2101 accaggtgaa aaaacatacg aagtagtaaa acatttagta gatgaattta ttcttgtatc
     2161 agaagaggaa atagaacatg caatgcaaga tttaatgcaa cgtgccaaaa tcattacaga
     2221 aggtgcagga gctttaccta cagcagctat tttaagtggg aaaattgata aaaaatggct
     2281 agagggtaaa aatgtcgttg cattagtttc aggaggaaac gttgacttaa ctagagtttc
     2341 tggtgtcatt gaacatggct taaatatcgc ggatacaagt aagggtgtgg taggttaaaa
     2401 cttccaatct taaaaatgag gtgtaattat gtcaaatggt aaagaattac aaaaaaatat
     2461 aggtttcttc tcagcgtttg ctattgttat ggggacagtt attggttcag gagtattctt
     2521 taaaatatca aacgtaacag aagtaacagg aacagcagga atggccttgt ttgtatggtt
     2581 cctaggcggc atcattacca tttgtgcggg gttaacagca gcagaacttg ctgctgcaat
     2641 ccctgaaaca ggtggcttaa cgaagtatat agaatataca tacggtgatt tctggggctt
     2701 cctatcaggt tgggcgcaat catttattta ttttccagct aacgtagcag cattgtctat
     2761 cgtatttgcg acacagctaa ttaatttatt ccatttatct ataggttcgt taataccaat
     2821 agcaatcgca tctgcgttat ctattgtgtt gataaatttc ctaggttcaa aagcaggcgg
     2881 aattttacaa tcagttactt tagtaattaa actgattcca atcatcgtta ttgtaatttt
     2941 tggtattttt caatctggag atatcacttt ttcattaatt ccaactacag gtaattcagg
     3001 aaatggtttc tttacagcaa ttggtagtgg tttattagca actatgtttg catatgatgg
     3061 ttggattcat gtaggaaatg ttgcggggga acttaaaaat cctaaacgcg atttaccttt
     3121 agcgatttca gttggtatcg gttgtattat ggctgtgtat ttattaatta acgctacatt
     3181 tttattaacg ttgccaatag aactacttgc tggtaactta aatgcagctt cagatacatc
     3241 aaaaatatta tttggtgaaa atggcggtaa aattattaca atcggtatat taatttctgt
     3301 ttatggtacg atcaatggct atactatgac tggtatgcgc gtaccatatg caatggctga
     3361 aagaaaatta ttgccattta gccacttatt cgcaaaatta acaaaatctg gcgcaccatg
     3421 gtttggcgca attatacaac ttataatcgc tatcatcatg atgtcaatgg gagcatttga
     3481 tacaataaca aacatgttaa tctttgttat ttggttgttc tattgtatgt catttgttgc
     3541 tgtaataatt ttaagaaaac gtgaaccaaa tatggagcgt ccatataaag taccgttata
     3601 tccgatcata cctttaattg ctattttggc aggatcattt gtattgatta atacactgtt
     3661 tacacaattt atattagcaa tcattggaat tctaataaca gcacttggta taccagttta
     3721 ttactataag aagaaacaaa aagcagcata aggtaagata actagcattg agaataaatg
     3781 gatggactac taataaattt aaagttttac acattaaaat caaaaaccat tcaattattc
     3841 tatcgaacag acaaatttct gttatggaat ttgtctgttt tcaaaagtat agggaggcaa
     3901 atagagatgg aaaagccgtc aagagaggca tttgaaggca ataataagtt gttaatagga
     3961 attgttttaa gtgtaataac gttttggcta tttgcacaat cattggttaa tgttgtacca
     4021 atacttgaag atagtttcaa tacagatatt ggaacggtta atatcgccgt tagtataact
     4081 gctttatttt caggaatgtt tgttgtagga gcaggtggtc ttgctgataa atatggcaga
     4141 attaaactca cgaacattgg tattatctta aatatattgg gttcattatt aatcattatt
     4201 tcaaatattc ctttattact tattatagga agattaattc aaggactttc agcagcatgt
     4261 attatgcctg caactttgtc tattattaag tcatattaca ttgggaaaga tagacaacgc
     4321 gctttaagtt attggtcaat tggctcatgg ggcggctctg gtgtttgttc attttttgga
     4381 ggtgcagttg caacactttt aggttggcgt tggattttca tcctatcaat tataatttca
     4441 ttaattgcgc tgtttcttat taaaggcaca cctgaaacta aatctaaatc gatttctcta
     4501 aataaatttg acattaaagg tctggttctt ttagtcatta tgctcctcac tttaaatatt
     4561 ttaattacta aaggatcaga attaggtgta acctcacttc tttttatcac tttattagca
     4621 attgcaattg gatcttttag tttatttata gttcttgaaa agcgtgctac aaatccttta
     4681 atcgatttta aattatttaa aaataaagct tatacaggtg caacagcttc aaactttttg
     4741 ttaaatggtg ttgcgggaac attaatagta gccaacacat ttgttcaaag aggtttagga
     4801 tattcctcat tgcaagcagg aagtttatca atcacttatt tagtaatggt actaattatg
     4861 attcgtgttg gtgaaaagtt acttcaaaca ctcggatgca agaaaccaat gttaattgga
     4921 acaggagttc ttattgtcgg agaatgtctc atttcattaa ctttcttgcc agaaatattg
     4981 tatgtcattt gttgtattat aggttattta ttctttggtt taggactagg aatatatgct
     5041 acaccatcaa cagatacagc aattgcaaat gcaccgttag aaaaagtagg agttgctgca
     5101 ggtatctata aaatggcttc tgcattaggt ggagcatttg gcgtcgcatt gagtggtgca
     5161 gtttatgcaa tcgtatcaaa tatgacaaac atttatactg gtgcaatgat tgcattatgg
     5221 ttaaacgcag gtatgggaat attatcattc gttatcattt tgttacttgt gcctaaacaa
     5281 aacgacactc aattatgata attgagaatt aaattgaaat catacaagtc gctacaatat
     5341 taaacaaaaa tataaaccga ttcttatgtg tcattatttt aaatgaacat agggattggt
     5401 tttttattac tctttta
//
LOCUS       DAPDIM010000111         5381 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000111 DAPDIM010000000
VERSION     DAPDIM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5381
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.113"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            62..736
                     /locus_tag="RFE25_002674"
     CDS             62..736
                     /locus_tag="RFE25_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817690.1"
                     /translation="MPKITSYITQDDGTTTVVISGVELGNKETLLLDNGFDVEVDVSV
                     IDPFRITGKQRRKIFALVKDIEEYTGQPMDYMRHMFIEYVRTYYGYDERISLSNCTRT
                     QASQIIEATLDWTFYNDIPLSYKTSNLLKRDKSFLYWSTVNCNCVICGKPHADLAHYE
                     AVGRGMNRNKMNHYDKHVLALCREHHNEQHAIGVKSFDDKYHLHDSWLKVDERLNKML
                     KGEKEK"
     gene            complement(846..1505)
                     /locus_tag="RFE25_002675"
     CDS             complement(846..1505)
                     /locus_tag="RFE25_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016028252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817691.1"
                     /translation="MNNLKKCFIACPIGTDDSKVRRNSDFLLQSIIKPALESDFEIQR
                     SDLISSTNKITDEIIGGLTNSELVIVDLSTHNPNVFYELGYRHALERPTITMINKDEN
                     IPFDVSAYRTIYYSELYADVVNAKDQLKETIKTFTDNDFNFENPVNKYNNIDNEYGVL
                     NRHLLDIKSDLSELKEFLPSVTKQDPDIPADSMVRMMELAVQYPDQFERLMELQNKNS
                     Q"
     gene            1551..2321
                     /locus_tag="RFE25_002676"
     CDS             1551..2321
                     /locus_tag="RFE25_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDU2817692.1"
                     /translation="MATFRTIKESGDFVTVHKSFVFDSNLSAKAKGILLYFLSRPDNW
                     QIYTSEVVKHMNDGQKSINSGVQELMDNKYVHRIQKRAENGVFKGFEYLVYEKPTEMP
                     FSENGLSANGFSENGKTENRKGRTTNNNSTNNDLTNNNNTNNDGSILSGNPTVYSIPY
                     KEIIEYLNKKAGKHFKHNTAKTKDFIKARWNQDFRLEDFKKVIDIKTAEWLNTDSDKY
                     LRPETLFGSKFEGYLNQKIQPTGTDQLERMKYDESYWD"
     gene            2331..3110
                     /locus_tag="RFE25_002677"
     CDS             2331..3110
                     /locus_tag="RFE25_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDU2817693.1"
                     /translation="MKPLFSEKINESLKKYQPTHVEKGLKCERCGSEYDLYKFAPTKK
                     HPNGYEYKDGCKCEIYEEYKRNKQRKINNIFNQSNVNPSLRDATVKNYKPQNEKQVHA
                     KQTAIEYVQGFSTKEPKSLILQGSYGTGKSHLAYAIAKAVKAKGHTVAFMHIPMLMDR
                     IKATYNKNAVETTDELVRLLSDIDLLVLDDMGVENTEHTLNKLFSIVDNRVGKNNIFT
                     TNFSDKELNQNMNWQRINSRMKHNARKVRVIGDDFRERDAW"
     gene            3104..3262
                     /locus_tag="RFE25_002678"
     CDS             3104..3262
                     /locus_tag="RFE25_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817694.1"
                     /translation="MVTKEFLKTKLECSDMYAQKLIDEAQGDENKLYDLFVQKLAERH
                     TRPAIVEY"
     gene            3275..3496
                     /locus_tag="RFE25_002679"
     CDS             3275..3496
                     /locus_tag="RFE25_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3269 family protein"
                     /protein_id="HDU2817695.1"
                     /translation="MPKEKYYLYREDGTEDIKVIKYKDNVNEVYSLTGAHFSDEKKIM
                     TDSDLKRFKGAHGLLYEQELGLQATIFDI"
     gene            3506..3913
                     /locus_tag="RFE25_002680"
     CDS             3506..3913
                     /locus_tag="RFE25_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDU2817696.1"
                     /translation="MEIEIKFNETFEAPMGSPRPRFRNTGRFVQTYMPTAYTNHKAYI
                     QGQMPKLNLERALKIELDFYFPLLKSWSKKKKSEMVGQYKVTKPDIDNLIKTVLDACN
                     GHVWKDDNQITEITSSKRYGLEPKIIMRVEEVI"
     gene            3913..4098
                     /locus_tag="RFE25_002681"
     CDS             3913..4098
                     /locus_tag="RFE25_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001187261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3113 family protein"
                     /protein_id="HDU2817697.1"
                     /translation="MQQQAYINATIDIRIPTEVEYQYFDDVDIEKEALADYLYNNPDE
                     LLEYDNLKIRNVNVEVE"
     gene            4099..4458
                     /locus_tag="RFE25_002682"
     CDS             4099..4458
                     /locus_tag="RFE25_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817698.1"
                     /translation="MSVVKINGKPYKFTEHENGLIKKNGLTPGMVAKRVRGGWALLEA
                     LNAPYGMRLAEYKEIVLSRIMQRESKEREIARQRRKEVELRKRKPHLFNVPQKHSRGP
                     YWFDNTYNQMFKKWQEA"
     gene            4459..4707
                     /locus_tag="RFE25_002683"
     CDS             4459..4707
                     /locus_tag="RFE25_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phi PVL orf 51-like protein"
                     /protein_id="HDU2817699.1"
                     /translation="MPKTDNARKEYLNQFFGSKRYLYQDNERVAHIHVVNGTYYFHGH
                     IVPGWQGVKKTFDTAEELEIYIKQHGLEYEEQKQLTLF"
     gene            4720..5121
                     /locus_tag="RFE25_002684"
     CDS             4720..5121
                     /locus_tag="RFE25_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817700.1"
                     /translation="MKIKVKKEMRLDELIKWARENPELSKGKIFLAKVFSNGFVRFQR
                     NTNTCSISSFIPIDTPFIVEVEEEITEDTVFDRLFEVYELQEGAYMSALHTSISINER
                     LENTFFPTKAFYILNDGLTMTLIWKGGRLVE"
     gene            5118..>5381
                     /locus_tag="RFE25_002685"
     CDS             5118..>5381
                     /locus_tag="RFE25_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817701.1"
                     /translation="MNYETGFQLSVMDARLKKMRKQRDEYKKQRYELIGVIAKLRDCN
                     KELEKKASAWDRYCKSVERDLINKFGNDDERVKFGMELNNKIFM"
BASE COUNT         2049 a          830 c         1071 g         1431 t
ORIGIN      
        1 taatcacaaa gatgttactg atatacatgg taataaatat aaatttgaga agttgatata
       61 aatgccgaaa attactagtt atatcactca agatgacggt acaacaacag ttgtcatctc
      121 gggtgttgaa ttaggtaata aagaaacatt actacttgat aacgggtttg atgtggaagt
      181 cgatgtgagc gtcatagatc cgtttcgaat taccggcaag caacgacgaa aaatattcgc
      241 gcttgtcaaa gacatagaag aatatacagg tcaaccaatg gactatatgc gacatatgtt
      301 catcgagtat gtaaggactt actacggcta tgatgaacgt atttcactaa gtaattgtac
      361 gagaacacaa gcaagtcaaa tcattgaagc aacgcttgac tggacgttct acaatgacat
      421 accacttagc tacaaaacga gtaatctact gaaacgagat aaatcattct tatactggtc
      481 aactgttaac tgcaactgtg taatatgcgg aaagcctcac gctgacttag cacattacga
      541 agcagtaggt agaggcatga acagaaacaa gatgaatcac tacgacaaac atgtattagc
      601 gttatgtcgc gaacatcaca acgagcaaca tgcgattggc gttaagtcgt ttgatgataa
      661 atatcacttg catgactcat ggctaaaagt tgatgagagg ctcaataaaa tgctgaaagg
      721 agagaaagag aaatgaacaa aatattaata cgctttgcta ttaactatat aaaatatcaa
      781 caaaaacaat tgcgtgaaaa agaagcccga attaaatatc tagagggctt cttaaaaggg
      841 aagggttatt gactgttttt gttttgcaat tccatcaatc tttcaaattg atctggatac
      901 tgaacggcaa gttccatcat tcttaccata gaatcagcgg gaatatcagg gtcttgtttg
      961 gtcactgaag gtagaaactc ttttaattcg gataaatcgc tttttatatc taacaaatgt
     1021 ctatttaaaa caccgtattc attatcgata ttattatact tattgactgg attttcaaaa
     1081 ttgaaatcat tatctgtaaa tgttttgata gtttctttaa gttggtcttt ggcatttact
     1141 acatccgcgt ataattcgct gtagtaaatt gtacggtaag cgctaacatc aaaagggata
     1201 ttctcatctt tgttaatcat agtaattgtt ggtctctcta gagcgtgtct gtaacctaat
     1261 tcataaaata cgttcgggtt atgcgtactc aaatctacaa taactaattc agaattcgtt
     1321 aatccaccaa ttatttcatc agtgatttta ttggtcgatg atataaggtc agatcgttgg
     1381 atttcaaaat ctgattctaa agcaggtttt atgatggatt gtaaaagaaa atcagagttt
     1441 cttcttactt tagaatcatc agtacctata gggcaagcaa tgaaacattt tttcaagtta
     1501 ttcactccta atcatatttt tattaattat aacagaaagg agataaaaaa atggcaacat
     1561 ttagaacgat aaaagaaagt ggcgattttg taactgtgca taaatctttt gtgttcgata
     1621 gtaatttaag tgctaaagct aaagggatat tattgtattt cctaagtcgt cctgacaatt
     1681 ggcaaatata cacgtcagaa gtagttaaac atatgaatga tggacaaaaa tcaatcaata
     1741 gtggcgttca agaacttatg gataataaat atgttcacag aatacaaaaa agagctgaaa
     1801 acggtgtgtt taaaggtttt gaatacttag tttacgaaaa accaaccgaa atgccatttt
     1861 cggaaaacgg attatcggca aacgggtttt cggaaaacgg aaaaacggaa aaccgaaaag
     1921 ggcgtactac taataataat agtactaata atgatttaac taataataac aatactaata
     1981 atgatggaag tatattgtcg ggcaacccga ctgtgtattc cattccctat aaagaaatta
     2041 tcgaatactt aaataaaaaa gcaggaaagc attttaaaca taatacagct aaaacaaaag
     2101 attttattaa agcaagatgg aatcaagatt ttaggttgga ggattttaaa aaggtgattg
     2161 atatcaaaac agctgaatgg ttaaacacgg atagcgataa ataccttaga ccagaaacac
     2221 tttttggcag taaatttgag gggtacctca atcaaaaaat acaaccaact ggcacggatc
     2281 aattggaacg catgaagtac gacgaaagtt attgggatta gggggatatt atgaaaccac
     2341 tattcagcga aaagataaac gaaagcttga aaaaatatca acctactcat gtcgaaaaag
     2401 gattgaaatg tgagagatgt ggaagtgaat acgacttata taagtttgct cctactaaaa
     2461 aacacccgaa tggttacgag tataaagacg gttgcaaatg tgaaatctat gaggaatata
     2521 agcgaaacaa gcaacggaag ataaacaaca tattcaatca atcaaacgtt aatccgtctt
     2581 taagagatgc aacagtcaaa aactacaagc cacaaaatga aaaacaagta cacgctaaac
     2641 aaacagcaat agagtacgta caaggcttct ctacaaaaga accaaaatca ttaatattgc
     2701 aaggttcata cggaactggt aaaagccacc tagcatacgc tatcgcaaaa gcagtcaaag
     2761 ctaaagggca tacggttgct tttatgcaca taccaatgtt gatggatcgt atcaaagcga
     2821 catacaacaa aaatgcagta gagactacag acgagttagt cagattgtta agcgatattg
     2881 atttacttgt actagatgat atgggtgtag agaacacaga acatacttta aacaaacttt
     2941 tcagcattgt tgataacaga gtaggtaaaa acaacatctt tacaactaac tttagtgata
     3001 aagaactaaa tcaaaatatg aactggcaac gtatcaattc aagaatgaaa cacaatgcaa
     3061 gaaaagtaag agtaatcgga gacgatttca gggagcgaga tgcatggtaa ccaaagaatt
     3121 tttaaaaact aaacttgagt gttcagatat gtacgctcag aaactcatag acgaggcgca
     3181 gggcgacgaa aataagttat atgacctatt tgtccaaaaa cttgcagaac gtcacacacg
     3241 ccccgctatc gtcgaatatt aaggagtgtt aaaaatgccg aaagaaaaat attacttata
     3301 ccgagaagat ggcacggaag atattaaggt catcaagtat aaagacaacg taaatgaagt
     3361 ttattcgctc acaggagccc atttcagcga cgaaaagaaa attatgactg atagtgacct
     3421 aaaacgattt aaaggcgctc acgggctttt atatgagcaa gagctaggat tacaagcaac
     3481 gatatttgat atttagaggt ggcacatgga aatagaaatt aaatttaacg aaacgttcga
     3541 ggcacctatg ggctcgcctc gtccacgctt tcgtaataca ggtagatttg ttcaaacata
     3601 catgccaaca gcttatacaa atcataaagc gtatatacaa gggcaaatgc ctaagttaaa
     3661 tctagagcgc gcactaaaaa tcgaattaga cttttacttt ccattactta aatcatggtc
     3721 gaagaaaaag aaaagtgaaa tggttggaca gtataaagtg actaagccgg atatcgataa
     3781 cttaattaaa acagtattag acgcatgtaa tggtcatgtg tggaaagacg ataaccaaat
     3841 tacagaaata actagctcaa agcgttatgg actagaacca aaaataatca tgcgagttga
     3901 ggaagtgatc taatgcaaca gcaagcatat ataaacgcaa cgattgatat aaggatacct
     3961 acagaagttg aatatcagta ttttgatgat gtggatatcg aaaaagaagc gctggcagat
     4021 tacttatata acaatccaga cgaattacta gagtatgaca atttaaaaat tagaaatgta
     4081 aatgtagagg tggaataaat gagtgtcgtg aagattaacg gtaaaccata taaatttacc
     4141 gaacatgaaa atggattgat aaaaaagaac gggttaactc ctggaatggt tgcaaaaaga
     4201 gtacgtggtg gctgggcgtt gttagaagcc ttaaacgcac cttatggcat gcgcttagct
     4261 gagtataaag aaatcgtatt atccagaatt atgcaacgag agagcaaaga acgtgaaata
     4321 gctaggcaac gacgtaaaga ggttgaacta cgtaagagga aaccacattt gtttaatgta
     4381 ccacaaaaac attcacgtgg tccgtactgg tttgataata cttataacca aatgtttaag
     4441 aaatggcagg aagcataaat gcctaaaacc gataacgcac gcaaagaata cttaaaccaa
     4501 tttttcggct ctaagagata tctgtatcag gataacgagc gagtggcaca tatccatgta
     4561 gtaaacggca cttattactt tcatgggcat atcgtaccag gttggcaagg cgtgaaaaag
     4621 acatttgata cagcggaaga gctcgaaata tatataaagc aacatggttt ggaatatgag
     4681 gaacagaagc aactaacttt attttaagga gatgtaaaaa tgaaaatcaa agttaaaaaa
     4741 gaaatgagac tagatgaatt aattaagtgg gcgcgagaaa atccggagct atcaaaagga
     4801 aaaatttttc ttgcaaaagt ttttagtaat ggattcgttc gttttcaacg aaatacaaat
     4861 acgtgttcga tatcaagttt tattccaatt gatactcctt tcatagttga agttgaagag
     4921 gaaatcacag aagatacagt atttgatagg ttgtttgaag tgtacgagct tcaagaggga
     4981 gcctatatgt cagcgttaca cacaagtatt agtatcaacg aacgtttaga gaacacgttt
     5041 ttccctacca aagcattcta catcttgaac gacggcctaa ctatgacatt aatttggaaa
     5101 ggtgggagat tggtagaatg aactatgaaa cagggttcca actaagcgta atggacgcta
     5161 ggttgaagaa gatgagaaaa caacgtgatg agtacaagaa gcaacgatat gagcttattg
     5221 gggttatagc gaagttacga gattgtaaca aagaactgga gaagaaagca agcgcatggg
     5281 ataggtattg caagagcgtt gaaagagatt taataaacaa attcggtaac gatgatgaaa
     5341 gagttaaatt cggaatggaa ttaaacaata aaatttttat g
//
LOCUS       DAPDIM010000112         5231 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000112 DAPDIM010000000
VERSION     DAPDIM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5231
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.114"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            44..307
                     /locus_tag="RFE25_002686"
     CDS             44..307
                     /locus_tag="RFE25_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817702.1"
                     /translation="MNMHILYNLRTKHNLEIDELAQQLNEKYGTKYEAHQIWEWENHH
                     HEPKFKDAMHLADFFDAPYEMFLESKVKEYQKHLEEVDIRMDK"
     gene            complement(444..1016)
                     /locus_tag="RFE25_002687"
     CDS             complement(444..1016)
                     /locus_tag="RFE25_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDU2817703.1"
                     /translation="MKLKSLAVLSMSAVVLTACGNDTPKDETKSTESNTNQDTNTTKD
                     VIALKDVKTSPEDAVKKAEETYKGQKLKGISFENSNGEWAYKVTQQKSGEESEVLVAD
                     KNKKVINKKTEKEDTVNENDNFKYSDAIDYKKAIKEGQKEFDGDIKEWSLEKDDGKLV
                     YNIDLKKGNKKQEVTVDAKNGKVLKSEQDH"
     gene            complement(1197..1565)
                     /locus_tag="RFE25_002688"
     CDS             complement(1197..1565)
                     /locus_tag="RFE25_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDU2817704.1"
                     /translation="MKTILKTITYLALTIIGAYAALFILKTIDSHGITDQFNPLVKED
                     DSYVKTTEVSTRMDDQLRSYTQSAFNKEGKETQLMYTATFDVKPHRYLKITHKGHHVE
                     TFEEVEKEEVPKKALDKLSR"
     gene            complement(1934..2545)
                     /locus_tag="RFE25_002689"
     CDS             complement(1934..2545)
                     /locus_tag="RFE25_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDU2817705.1"
                     /translation="MFKKYDSKNSIVLKSILSLGIIYGGTFGIYPKADASTQNSSSVQ
                     DKQLQKVEEVPNNSEKALVKKLYDRYSKDTINGKSNKSRNWVYSERPLNENQVRIHLE
                     GTYTVADRVYTPKRNITLNKEVVTLKELDHIIRFAHISYGLYMGEHLPKGNIVINTKD
                     GGKYTLESHKELQKDRENVKINTADIKNVTFKLVKSVNDIEQV"
     gene            2751..3464
                     /locus_tag="RFE25_002690"
                     /pseudo
     CDS             2751..3464
                     /locus_tag="RFE25_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270135.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            3503..4441
                     /locus_tag="RFE25_002691"
     CDS             3503..4441
                     /locus_tag="RFE25_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HDU2817706.1"
                     /translation="MLNFDEQIAKLKQMNIFFNIIDTEKANEILRKNNYFFKLAYFRK
                     NFEKKNGGYFIEFAYLSDLATIDMKLRYTMLHLTLDIEHSLKCLVLKLITENNQEDGY
                     KIIDEFLCIDKSYSNSNFDTNSRTPEEVMETKIKNKNEIFKHMNKRGQLPEKLNKYYQ
                     NPPAWVCIEFMQLGQFVSFLNFYYKKYNDEELRVANILMPLVKNIRNKSAHNQPIIAN
                     LNYDSRSPQYLFEKGNNIGISRNMFGIKNFIDTFATLELHNQVCSNAIIQARYHDLDQ
                     LQKRYKRNESYYNNALAIKRFFIALDKIIDFNRPKV"
BASE COUNT         1835 a          829 c          727 g         1840 t
ORIGIN      
        1 gagcatcttt gaattttaaa tcaagaagcg aggttaatga acaatgaata tgcatatttt
       61 atataactta cgaactaaac ataatttaga aattgacgaa ttagcacagc aattaaatga
      121 gaaatatggt actaaatatg aagcacatca aatttgggaa tgggagaatc atcatcatga
      181 acctaaattt aaagatgcca tgcatttagc tgacttcttt gatgcaccat atgaaatgtt
      241 tttagaaagt aaggttaaag aatatcagaa acatttagaa gaagtcgata ttcgcatgga
      301 taaatagatg caattaaacc ctcacaacac gtttggcata tatcctttca cgtcaaacag
      361 gacttatgca taagtattgt gagggtattt tattaattaa tatgaattaa gacattttac
      421 aagcgttaat gcaacgaatc tttttagtga tcttgctcac tctttaatac tttaccgttc
      481 ttagcatcaa cagtaacttc ttgtttttta ttaccttttt tcaaatcgat attgtaaaca
      541 agtttgccat catctttttc aagtgaccat tctttaatat caccatcaaa ttctttttgt
      601 ccttctttaa tggctttttt gtaatctata gcatcgctat atttaaagtt atcattttca
      661 ttcactgtat cttctttttc agtctttttg ttaatcactt ttttattttt atcagcaaca
      721 agtacttctg actcttcacc agatttttgt tgcgtcactt tataagccca ttcaccatta
      781 gaattttcaa atgaaattcc tttcaacttt tggcctttgt atgtttcttc agcttttttc
      841 acagcatctt ctgggcttgt tttaacatct tttaaagcaa taacatcttt tgttgtatta
      901 gtgtcttgat tagtatttga ctctgttgat tttgtttcat cttttggagt atcattgcca
      961 catgcagtaa gcaccaccgc tgacattgat aacactgcta atgattttaa tttcataata
     1021 tcactctctc ttcctatttt tgaaactcat aacaaaagct tatatgctat atagattgta
     1081 ttaccccttg tttttaattt tattcataat tattacaaat atttttaaat taatcgtcat
     1141 gcgttacttt cgttcgtact ccttttataa atgaaccatg taatataagc atgctattat
     1201 cgactcagtt tgtctaatgc tttctttggt acttcttcct tttcaacttc ttcaaaagtt
     1261 tctacatgat gacctttatg tgtaattttc aagtatctat gcggtttaac atcaaatgta
     1321 gcagtataca ttaattgcgt ctctttccct tctttattaa aagcactttg agtataactt
     1381 cggagttgat catccattct agtagacacc tctgtcgttt taacataaga atcatcttcc
     1441 tttactaatg ggttaaattg atctgttata ccatgagagt ctattgtttt taaaatgaat
     1501 aaagcagcat aagcgccaat gatagtaagt gcaagatatg ttattgtttt taaaatcgtt
     1561 ttcaaaagat cacctctgac aaaatataaa ataggatgcc tctgaaaaca acttacataa
     1621 ttgtaattaa agtgtaagta ttaggagaaa atgatggtat ttgaacctga aagatacgaa
     1681 tcgtttttaa actaagttat tttatagaga ctttattatg gaattgaaag aagttaattt
     1741 taaggttgtc gaatgtaaaa acatattgat taaccataaa agagaaatta tatttgtaga
     1801 tttcggcata aacgtcatta aagaattttc tatatgatag tgctaatcat aacaaagaaa
     1861 gctaggcacc tttagatacc taactttcaa agtattagca ataaaacact gtatatacta
     1921 attcaactta atttcaaact tgttcaatgt cattaacact tttcacaagt ttgaaagtta
     1981 cattttttat atcggctgta ttaattttta cattttccct atctttttgt agctctttat
     2041 gcgactctaa tgtatattta ccgccatctt ttgtatttat gacgatgtta cctttaggca
     2101 aatgttctcc catatataag ccataagaaa tatgagcaaa tcttatgata tgatccaatt
     2161 cctttaaagt gacaacttct ttattaagag taatatttct cttaggtgta tatactctat
     2221 cagcaactgt gtatgttcct tctaaatgta tacgaacttg gttttcattt aaaggtctct
     2281 ctgaataaac ccaattccta gatttattag attttccatt tattgtatcc ttgctgtatc
     2341 tatcgtaaag ttttttaacc aaagcttttt ctgaattatt tggtacttct tcaacttttt
     2401 gtaattgttt atcttgtaca cttgaggaat tttgtgttga cgcgtctgct tttggatata
     2461 ttccaaatgt tcccccatag atgataccta gcgatagaat agattttaat acgattgaat
     2521 tttttgagtc atattttttg aacatattta attacctcct tgatgtaaag ctttatttgc
     2581 tacaattata aaaataatag acgtgttcat gaattaaatt catcttaact cttgattaac
     2641 tttaatttgc taccactctg aatttaataa ctataaatcg tctacacata attggacaaa
     2701 atctaagaga ataaaatttg ttaatttaaa atagcaagca attcaaagtt atatgtgtaa
     2761 tagataaaat agatatccct atagtgatgc gttactagct aaacatagta acacattaga
     2821 agataatgaa gttaaggagt tactggattg tttcgactat gtaattaagt ataaaaatat
     2881 ccaacgacaa aacgtaatta taaaatggta aaagctatgg tacagtttca aattgctaat
     2941 gacatgcgta tcggtgagct acttgcaata aagagagtaa atataaacta tgaagataaa
     3001 acgctagata tcgacggtaa agttaattgg ataactgaaa aatgacggga gcatccggag
     3061 taaaagagac aactagaaca agtaacagct atagggctat aggcctcact atccatagca
     3121 tcgacttact aagaacactt atgcttgtaa tgataagttt attaatatag ggtacatatt
     3181 cacaaatgca gctggtggcc ctatcgactc gaacaaaatt agcaacatta ttaaaggggg
     3241 cactatcaaa gagacaactg agattagttc tattaagaaa cctgtaacga cgcatacatt
     3301 acatcattcg catatatcta cacttgctca attaggaatt aacttaaaag caatgcaaga
     3361 gcatgtaggt cattcagatt ataaaaaatc tagagatata cacacatgtt actaatcaga
     3421 tggcgaaaga tatgatgaat aaatttgaac gattggggag ttaaaattgg aaaaagatga
     3481 tatactagca gaaattaagc ctatgctcaa ttttgatgag caaatagcga aattaaaaca
     3541 gatgaatata ttttttaata ttattgacac cgaaaaagca aatgaaattc ttagaaaaaa
     3601 taattacttc ttcaaactag cttatttccg aaaaaatttc gaaaaaaaga atggcggcta
     3661 tttcatagaa tttgcttatt tatcagattt agcaactata gatatgaaat taagatacac
     3721 aatgttgcat ttaactttag atattgaaca tagtttaaag tgtctagtct taaaactaat
     3781 aacagaaaat aaccaagaag atggttataa aataatagat gagttcttat gtattgataa
     3841 atcatatagc aattcaaatt ttgacacaaa ttcaagaaca ccagaagaag ttatggaaac
     3901 caaaatcaaa aataaaaacg aaatattcaa gcatatgaat aaacgaggac aactacccga
     3961 gaagttgaat aaatactatc aaaatccacc cgcatgggtt tgcattgaat tcatgcaact
     4021 aggtcaattc gtttcgtttc tcaacttcta ttacaagaag tacaatgacg aagaattgag
     4081 agttgctaat attttaatgc ctttagttaa aaatataaga aacaaatcag ctcataacca
     4141 acccatcata gcaaatctaa attatgacag tagatctcct caatatttat ttgaaaaagg
     4201 gaataatata ggcatatcta gaaacatgtt cggaataaaa aatttcatag atactttcgc
     4261 tacgctagaa ttacataatc aagtttgtag taatgcaatt atccaagcaa gatatcacga
     4321 tttggaccaa cttcaaaagc gatataaaag aaacgaaagc tattataata atgcattagc
     4381 tatcaaaaga ttttttatag ctttagataa aattattgac ttcaacagac caaaagtata
     4441 aactatctag tgaggaaaga gacttatagg tctcgcgagt tattttaatt cgtatgcaag
     4501 aaaaagaaga gctatgcatt ttatttaaaa tgcgtagttc tttttttatg catctaaatt
     4561 catattattt ttgcaatata aacatatctt tgtgcaaatt ccgaacacaa aacattcaca
     4621 tcatcctttt ttgccctttt ctgtcccttt tctatatccc aaacataaaa aaatccccca
     4681 taagcctatg cctacgaggg ttataatata ttaaatatta ttgttcttct tttatatact
     4741 gctattttat gaataatcat tagtgttcaa aaagctgtta aatcaatgtt tcatactcat
     4801 attgttcatt ttgaaagtct atgaacattc acactatttc gtaactttgc gaactttttg
     4861 cgaacatact acccttgccc ctagtttcac aattacacct tttttcgcct ttataacaac
     4921 cacactccta gatcaatagg ttgtaaggtt tgaatgtacc tatagcactg aacattttaa
     4981 tgggctatac ttctcaacaa ttcacatcac ttcataatta acgtattgca atatgtattc
     5041 accgcctgca aagtatgagg tcatattttt atatcaatgt acaaaaaact gttttgccct
     5101 taaaacaacc acattcctga ttaataggta gtttagtttg agcattttat aattaacata
     5161 aaaaatagac aagtaccgaa gtacctgcct tatttctaaa tccacaggaa ttcattaata
     5221 taataattat a
//
LOCUS       DAPDIM010000113         5228 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000113 DAPDIM010000000
VERSION     DAPDIM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5228
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.115"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..143
                     /locus_tag="RFE25_002692"
     CDS             <1..143
                     /locus_tag="RFE25_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817707.1"
                     /translation="ISKNSGVPRQTVTDLKVGKTKIKEAKFKTIIKLYEYQRTLENKT
                     EC"
     gene            843..953
                     /locus_tag="RFE25_002693"
     CDS             843..953
                     /locus_tag="RFE25_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817708.1"
                     /translation="MKMTIKVRKTNKKEKIEFLIGTFIIILVILGFKIMK"
     gene            1377..1562
                     /locus_tag="RFE25_002694"
     CDS             1377..1562
                     /locus_tag="RFE25_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817709.1"
                     /translation="MSEYKKKIIELIESNLTGYEISKKTGVSQYVLSQLKQGKREVDN
                     LTLNTTEKLYEYANKVL"
     gene            2073..2177
                     /locus_tag="RFE25_002695"
     CDS             2073..2177
                     /locus_tag="RFE25_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817710.1"
                     /translation="MFKVNYSILSYYPEYNIAVSWQRLREGKTIKNKI"
     gene            2305..2556
                     /locus_tag="RFE25_002696"
     CDS             2305..2556
                     /locus_tag="RFE25_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817711.1"
                     /translation="MLTLIKLKEDEQVIIYEYIPEDDISNGKGSVTFNKKDAEVIDFS
                     LSEIENEEYFMLYRNKSFSVVRDFIEKQEFPENYKIAWY"
     gene            2632..2835
                     /locus_tag="RFE25_002697"
                     /pseudo
     CDS             2632..2835
                     /locus_tag="RFE25_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002463904.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            2920..3272
                     /locus_tag="RFE25_002698"
                     /pseudo
     CDS             2920..3272
                     /locus_tag="RFE25_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891995.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3279..3473
                     /locus_tag="RFE25_002699"
     CDS             3279..3473
                     /locus_tag="RFE25_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LSM domain protein"
                     /protein_id="HDU2817712.1"
                     /translation="MNLQSYIGKLVKLTLTNNKILIGKVIDFDDKVDNFDGYNSIEID
                     TGRITYDISENKIKTIVLQK"
     gene            complement(4017..5042)
                     /locus_tag="RFE25_002700"
     CDS             complement(4017..5042)
                     /locus_tag="RFE25_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low specificity L-threonine aldolase"
                     /protein_id="HDU2817713.1"
                     /translation="MISFENDYLEGAHEKVLKRLVDTNLVQASGYGFDQFTAQAIEKI
                     KDTIDCPNATIRFLVGGTQTNQVVINSMLESYEGVISADTGHVAVHEGGAIEYSGHKV
                     ITIPSKEGKVSASDVETYMETFKSDFKKDHMVFPGMVYISHPTEYGTLYSKSELEELC
                     KVCKQYQLPLFMDGARLGYGLMSDQSDMTIKDIAKYCDVFYIGGTKIGALCGEAIVFT
                     KNNEPKQFTTRIKHHGALLAKGRLTGIQFLELFTDNLYFNISRHAIEMANKMKDGFKN
                     KGYRLYFDSPTNQQFFILSNEKIAELEQKVKFAVWEKYDDQHRVVRFATSWATTEENL
                     NKLLELI"
BASE COUNT         2044 a          656 c          761 g         1767 t
ORIGIN      
        1 gtatttcaaa aaattcaggt gtaccacgtc aaacagttac agatttaaag gtaggtaaaa
       61 ctaaaataaa agaagctaaa tttaaaacga taatcaagtt atatgaatat caaagaacat
      121 tagaaaataa aacagaatgt taacaaaaat attttgttag gttaggtgga caagaaatta
      181 aatttctaat gatttcatgg ttgtctgtcc acgttttgtc cacctcaata agataatctc
      241 ttagttttag aaattgtaca tggttaaata atcaaaaatg catattatga aattatcatt
      301 gccattaaat cttgaataat ctttaagtga tgatattaaa ggctgaacac agtaaataag
      361 ttaattttaa tgcagtattc tatattatac atattttgta ataatgtttg tgcgaattat
      421 tttttattga caatttttta tattaaattg tgtaattggc atatatgatg atttgtgata
      481 attatattgt aatatagcat ttggtttatg attccaaaat taatagattt gaaaagtata
      541 ctttatttca tgaaagtttt tggtacattt atttgaaaat gtttttatta caaagttaca
      601 tggctaaatg tttcttaaca aaattaattt ttcgagtgta aagaatcgtg tggtaaacat
      661 aatttatata gattataagg aggtgaaaat ggtcgaggaa gttaaaacga taaaatagtt
      721 tgaatctttt gatttcaatt ctggtaggac tattgaattt gcaatctaat aagaatgtga
      781 ggtttgattt aatatgaagt catattcttt gaataaaata ttactttctc accattagta
      841 aaatgaagat gactattaaa gtgcgaaaaa caaataaaaa agagaaaata gaatttttaa
      901 tagggacgtt tataattatt ttagtaatat tagggttcaa aattatgaaa taaatgtata
      961 gtatttgaga aggctatatg actccggaaa aattaaagtc taaagatatc tcaatatcta
     1021 aaatctaaaa gactactgga gttagtagtt tgaatattga aagactctaa tctaataaaa
     1081 atacataaaa ggtttaactt tagaagtggt tgtaaacttc aatgaatatt aaacattgaa
     1141 gtttagtaaa aggcgtaagg tataaaagca atcgtttgtc tttgacaaag taattgatga
     1201 tgaaaagtcg ttaatatgtt gaaagaaaaa ttgataatat gaaatttaac tattatgaag
     1261 tgatgatagc cattaatgaa tagaaaaata ataaaatcat ttataaataa aaactacgtt
     1321 gagttcacag atttcgaaaa aagcagtaaa aattgtacag atatggagat gaaaaaatgt
     1381 cagaatacaa gaaaaagata attgaattaa ttgaaagtaa tttaacagga tatgaaattt
     1441 ctaaaaaaac tggagtttct caatatgtac tttcacaatt aaaacagggc aaacgcgaag
     1501 tagataatct aaccctgaat acaacagaaa aattatatga atatgccaat aaagttttgt
     1561 aatataacta ctgtataaat taatcaagct atgtttattt gatttaacta ttaataaaaa
     1621 tcatatggta aatggatatt ataatgatta aaatacaaaa atagtacatt ccaatttgtg
     1681 aaaaaggagt atgtcgtttc atttagaatt tattacacta aattagcatc gaataaggga
     1741 aaatgagtgt taagttttaa atgataaaat agattggaat ggatcgtctt gaaatgctcc
     1801 cttcaaagtt ttcatttttt caatgtctac ttcgaagggg catttccatt atattgttat
     1861 agctttttat atttgtataa tgaacatata agtttaagaa gatgagagtg aaggaaataa
     1921 aaaagctcaa atgtaccaaa ttgttaatct taataaatct ctactttata aagattgaat
     1981 ggacattcga gcgttaatca gtcaggaggg aatttcactc ctacaattta ataataatac
     2041 ttgcttcaac actgtacaag gagtgatttg ttatgttcaa agtgaattat tcgattttaa
     2101 gttattatcc agaatataat atcgcagtaa gttggcaacg tttaagagaa ggaaaaacaa
     2161 taaaaaacaa gatttaatac tgctgcgtca tgaggcgctt gaacattatt tgatgaataa
     2221 gtataatttc aactatgatt atgcatataa aattgtatca aaaaatacga ttattcaatt
     2281 tttataaaaa agaaggtgga ttaaatgctt acattaataa aattgaaaga agatgaacag
     2341 gttataatat atgaatatat acctgaagat gatataagta acggtaaagg ttcagtaact
     2401 tttaataaaa aagatgcaga ggttatagat ttctcattat ctgaaataga aaatgaagaa
     2461 tattttatgt tatatcgtaa taagtctttt tctgtagtaa gagactttat cgagaagcaa
     2521 gaatttcccg aaaattataa aatagcatgg tattaaagca tcctttctac acagataaag
     2581 agaaagcgat gctattttta tatgcttttt tcattattcg ttgaaaaaga agagtcacaa
     2641 aagttaacat atttaaaaga acttggtgaa gatgacgaat ataaatatgt tgccaaaata
     2701 gatagtaaaa catctaaatt atgtcattca ctcaacggaa aaatatttat agttaaagat
     2761 atgataccag gtgtgaatgc gccacctatg catccttggt gtagaagtac cacagtgcca
     2821 catgttggca attggtgaga caagttcatt aaagagcgtg aaggtaagta tcaagtagaa
     2881 gtaaaagaag caaaattaca agaaaaagct aaaaaagaaa tgcttgatat gataagtaat
     2941 ggtaaaataa agatgcaatt gaataatgaa aaacaacagc gtcatatttt aaacacaaat
     3001 gaatataata acaagaaaaa taattcatct ttcttaccca gttatattac aatagattct
     3061 aatgaaattg aaaaggtgac taaaaaagaa tttattgatt ttccagtttt gtttgatgat
     3121 gaagggaatt tcagaaaaaa acaagttata gattacaaaa agataatagg taaatcttat
     3181 gtgaatggta aatatatgtt gaaacgaaat taggtaaagt tcattattct aaaactggtt
     3241 ttcatgtagt tccgtatatt gaaaaggagt gattaaatat gaatttacag tcatacatag
     3301 gcaaattagt caaattaacg cttactaata ataaaatatt aattggaaaa gtgatagact
     3361 ttgatgataa agttgataat tttgatggtt ataattcgat agaaattgat acaggtagaa
     3421 ttacatatga tatatcagaa aataaaatta aaactattgt tttacaaaaa tagcatcctt
     3481 tctacacaga taaagagaaa gcggtgctat tttttgcact tttataacaa ctaaggatac
     3541 aagacatata ccttcaacaa tatcctcatt taaacctatc gatttcctaa gctcaatttt
     3601 aaacacaaag tttatttgaa atgatgcaca cctataaaaa tcttaatcat cgaaaagtca
     3661 caaacatctc catattaaaa acttaaatag tgcatttcat ttaaactaaa catagatatt
     3721 cttacaaata tatacttagt aattcgattg ttaatacatc actttcataa aataactata
     3781 accatcataa tacttctcaa atctcgtcaa attaaagtaa atacagcaca aattaacatt
     3841 tttaaatata taaaataaaa caagatactc aataatctgt agtatcttgt tttggaataa
     3901 tgtaatttta tatcatcaac ggcttcaaat gagtagtttc atataaatca ataaacacaa
     3961 ctactcaact gatcttaatt aataaatgat ttgtcagatg acacataaca gcattattag
     4021 attaattcta atagtttgtt taaattttct tcggttgtcg cccagctggt tgcgaatcta
     4081 acaacacgat gttgatcatc gtatttttcc caaacagcaa atttaacttt ttgttctaac
     4141 tctgctattt tctcgttact taaaataaaa aattgttgat tggttggaga atcaaagtaa
     4201 agacgatagc ctttattttt aaacccgtct ttcatcttat ttgccatttc gatagcatgt
     4261 ctgcttatat taaaatataa attgtccgta aataattcta aaaattgtat gcctgttaac
     4321 cgtccttttg ctaaaagggc accgtgatgt ttgattcgag tggtaaattg tttcggttca
     4381 ttatttttcg taaaaacaat ggcttccccg cataatgcac ctatcttcgt accacctata
     4441 taaaatacat cacaatattt agcgatgtct ttaatagtca tatctgattg atcactcatc
     4501 aatccatacc ctaatcgtgc accatccata aataatggaa gctgatattg cttacatact
     4561 ttgcataact cttccaattc tgatttagag tataaagtgc catattctgt aggatgagaa
     4621 atatatacca ttcctgggaa taccatatgg tcctttttaa aatcactttt aaatgtctcc
     4681 atgtaagttt caacatctga agcactaact tttccttcct tagagggtat agtaattact
     4741 ttatgtccac tatattcaat tgcaccaccc tcatgcacag caacatgacc agtgtctgct
     4801 gaaatgaccc cttcgtaact ttctaacatt gaattaataa caacctgatt ggtttgtgtt
     4861 ccacctacta aaaaacgaat tgtagcattt ggacaatcaa ttgtatcttt aatcttttca
     4921 attgcctgag ctgtgaattg atcaaagcca tatcccgaag cttgtacaag atttgtatct
     4981 actaatcgtt ttaatacttt ttcatgagca ccttctaaat aatcattttc aaatgagatc
     5041 actacatttc cccctaaaac taatatcagc attttaatat gataaactaa tttcaaaact
     5101 agttcgatat ttaaaatgta ttgtgaattg ttaaagtttg tatcgcatta tcgcgaagtt
     5161 gaataaatat attatacatc aaacaataca ttaagaaaat taattaattt ttaatcatag
     5221 cgactttt
//
LOCUS       DAPDIM010000114         5133 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000114 DAPDIM010000000
VERSION     DAPDIM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5133
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.117"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..281
                     /locus_tag="RFE25_002701"
     CDS             <1..281
                     /locus_tag="RFE25_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817714.1"
                     /translation="VTISMIFLGISSGLTRPQTINKLSSSSNLRVMLNYAETLYFIFN
                     IAFLLIGGYLYSIGTIQYLMLFMSLLTFIYLLTLFYLRRDQHENQHRI"
     gene            259..774
                     /locus_tag="RFE25_002702"
     CDS             259..774
                     /locus_tag="RFE25_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDU2817715.1"
                     /translation="MKINTEFKGNNIPYEYAAGADISDLINGNPIKSFPFEITELPKD
                     TKYLAWSLIDYDAIPVCGFAWIHWSVANVSITGDSISIKADLSRTKGDYVQGKNSFTS
                     GLLAEDFSEIENHYVGPTPPDKDHQYELTVYALDHSLNLKNGFYLNEFLKEVNQHKID
                     QTSINLIGRKI"
     gene            1085..1519
                     /locus_tag="RFE25_002703"
     CDS             1085..1519
                     /locus_tag="RFE25_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAP domain-containing protein"
                     /protein_id="HDU2817716.1"
                     /translation="MKLKSFITVTLALGMIATTGATVTSNEVSAAEKDKLPATQKAKE
                     MQNVPYTIAVDGIMAFNQSYLNLPKDSQLSYLDLGNKVKALLYDERGVTPEKIRNAKS
                     AVYTITWKDGSKKEVDLKKDSYTANLFDSNSIKQIDINVKTK"
     gene            complement(1776..1961)
                     /locus_tag="RFE25_002704"
     CDS             complement(1776..1961)
                     /locus_tag="RFE25_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HDU2817717.1"
                     /translation="MKHLVTFFWALLLMQMVNFVLNSLVGGDSLNVVNPIIMAVLFTI
                     FTAIFAAVIKPPKDSSQ"
     gene            2256..3197
                     /locus_tag="RFE25_002705"
     CDS             2256..3197
                     /locus_tag="RFE25_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDU2817718.1"
                     /translation="MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHW
                     ADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGK
                     VASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDG
                     AGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDAS
                     TRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPL
                     SIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK"
     gene            3209..4453
                     /gene="fabF"
                     /locus_tag="RFE25_002706"
     CDS             3209..4453
                     /gene="fabF"
                     /locus_tag="RFE25_002706"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDU2817719.1"
                     /translation="MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDT
                     EPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINDNTADRI
                     GVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGA
                     TVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIET
                     ACRPFQEGRDGFVMGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPE
                     GEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSS
                     TKSMTGHLLGATGGIEAIFSALSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITY
                     AMSNSLGFGGHNAVLVFKKFEA"
     gene            complement(4508..4879)
                     /locus_tag="RFE25_002707"
     CDS             complement(4508..4879)
                     /locus_tag="RFE25_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HDU2817720.1"
                     /translation="MLKKWLGMALITPILTFIIWVFNSHTIITYLNILFYVSLIIFIS
                     IFLILLVQEGIFDATSYGFRRLKYQMSSSKKKKSISDDPFFNPQEVKKEHYFVSTWII
                     PLLLINILYFIMTIVLSLILV"
BASE COUNT         1866 a          709 c          925 g         1633 t
ORIGIN      
        1 cagttactat ttctatgata tttttaggta tttcttcagg gttaactcgt ccacaaacta
       61 taaataaact ttctagcagt agtaacttaa gagtgatgct taattatgca gaaacgttat
      121 attttatttt taatatcgca tttttactta ttggtggtta tctatattca attggaacta
      181 ttcaatattt aatgttattt atgtcattat tgacgtttat atatttacta acattatttt
      241 atttaaggag agatcaacat gaaaatcaac acagaattta aaggaaataa tataccatat
      301 gaatatgcgg caggcgcaga tataagtgat ttaataaatg gcaatccaat taaatcattc
      361 ccgtttgaaa taacagaact tccaaaagat actaaatatc ttgcatggtc tctgatagat
      421 tatgatgcaa taccagtttg cggatttgca tggattcatt ggagcgttgc taatgtaagt
      481 atcactggtg attcaatttc tataaaagca gatttatcaa gaacaaaggg tgactatgta
      541 caaggtaaaa atagctttac tagtgggttg ttggctgaag atttttcaga aatagaaaat
      601 cactatgtag gaccaacacc acctgataaa gatcatcaat atgaattaac agtttatgcg
      661 ttagatcatt ctttaaattt gaagaatggg ttctacttga atgaattttt aaaagaagta
      721 aatcaacata aaattgatca aacaagtatt aaccttatag gaagaaaaat ttaatgctaa
      781 atatctcatc aatataaaat tgttcaatta aaagtacaaa gaaacaagag atttaattta
      841 tatattaggt acggcgttcg ctataatgca aagaagtaat taaatttaag aaatgtaaac
      901 ttagttattg taatgtgaat ttatttgaaa aaatagaaag tattaacaat tatagctttt
      961 acattaatta aaatttattt ttaaaaacaa gtaaacaatt tacatactta taatttttga
     1021 aacttttaga tttgtgttat attgattttg taagatactt taactcacaa aggagagaga
     1081 ttatatgaaa ttaaaatcat ttataactgt aactttggca ctgggcatga tcgcaacgac
     1141 tggcgctact gtgacaagta atgaggtatc tgcagcagaa aaggacaaac taccggcaac
     1201 tcaaaaagct aaagaaatgc aaaatgttcc atatacaatt gcagtagatg gcattatggc
     1261 tttcaatcaa tcttacttaa atttaccaaa agatagccaa ttatcatatt tagatttagg
     1321 aaataaagtt aaagctttat tatatgatga acgtggtgta acacctgaga agattcgaaa
     1381 tgcaaaatct gccgtttaca cgattacttg gaaagatggt agtaaaaaag aagtggatct
     1441 taagaaagat agctacacag caaacttgtt tgattcaaat tcaattaaac aaattgatat
     1501 taatgtaaaa actaaataaa cacttaaaat tatcaaattc aacatgaagc atttaatttt
     1561 acagtgatga ttataatata attgccttga tacaaagatt actcgtaaat gacatctttg
     1621 tattaaggct ttttctaaat ttaaaagtga tgggttagag gttattgagc tttaaaatat
     1681 tcaaaataca aaacattaat ggccaaaaat aaaagccgcc tttatctggg cagcttcaat
     1741 aataagaaag acatatttca ttttatacta aatagttatt gtgatgaatc tttcggcggt
     1801 ttaattactg cagcaaaaat tgctgtgaaa atcgtgaaca atactgccat gataattgga
     1861 ttcactacat ttaagctgtc tccacctact aggctattaa gtacaaagtt aaccatttgc
     1921 attaataata atgcccaaaa gaatgttacg aggtgtttca tgtcattcta cctccacttt
     1981 aattatatat attttatttt aagtgaaagt tagaaatttg tatagtaaca tctcatatat
     2041 tttgaccata ttatacagtt taaataaatg attttatctg aatggctatt caaatttaag
     2101 cgcattaaaa ccaatttcat actgaaattt gacgataata aagcattaaa attttattaa
     2161 ctagtcaata ttcctacctc tgacttgagt ttaaaaagta atctatgtta aattaatacc
     2221 tggtattaaa aattttatta agaaggtgtt caactatgaa cgtgggtatt aaaggttttg
     2281 gtgcatatgc accagaaaag attattgaca atgcctattt tgagcaattt ttagatacat
     2341 ctgatgaatg gatttctaag atgactggaa ttaaagaaag acattgggca gatgacgatc
     2401 aagatacttc agatttagca tatgaagcaa gtgtaaaagc aatcgctgac gctggtattc
     2461 agcctgaaga tatagatatg ataattgttg ccacagcaac tggagatatg ccatttccaa
     2521 ctgtcgcaaa tatgttgcaa gaacgtttag ggacgggcaa agttgcctct atggatcaac
     2581 ttgcagcatg ttctggattt atgtattcaa tgattacagc taaacaatat gttcaatctg
     2641 gagattatca taatatttta gttgtcggtg cagataaatt atctaaaata acagatttaa
     2701 ctgaccgttc tactgcagtt ctatttggag atggtgcagg tgcggttatc atcggtgaag
     2761 tttcagaagg cagaggtatt ataagttatg aaatgggttc tgatggcact ggtggtaaac
     2821 atttatattt agataaagat actggtaaac tgaaaatgaa tggtcgagaa gtatttaaat
     2881 ttgctgttag aattatgggt gatgcatcaa cacgtgtagt tgaaaaagcg aatttaacat
     2941 cagatgatat agatttattt attcctcatc aagctaatat tagaattatg gaatcagcta
     3001 gagaacgctt aggtatttca aaagacaaaa tgagtgtttc tgtaaataaa tatggaaata
     3061 cttcagctgc gtcaatacct ttaagtatcg atcaagaatt aaaaaatggt aaactcaaag
     3121 atgatgatac aattgttctt gtcggattcg gtggcggcct aacttggggc gcaatgacaa
     3181 taaaatgggg aaaataggag gataacgaat gagtcaaaat aaaagagtag ttattacagg
     3241 tatgggagcc ctttctccaa tcggtaatga tgtcaaaaca acatgggaga atgctctaaa
     3301 aggcgtaaat ggtatcgata aaattacacg tatcgatact gaaccttata gcgttcactt
     3361 agcaggagaa cttaaaaact ttaatattga agatcatatc gacaaaaaag aagcgcgtcg
     3421 tatggataga tttactcaat atgcaattgt agcagctaga gaggctgtta aagatgcgca
     3481 attagatatc aatgataata ctgcagatcg aatcggtgta tggattggtt ctggtatcgg
     3541 tggtatggaa acatttgaaa ttgcacataa acaattaatg gataaaggcc caagacgtgt
     3601 gagtccattt ttcgtaccaa tgttaattcc tgatatggca actgggcaag tatcaattga
     3661 cttaggtgca aaaggaccaa atggtgcaac agttacagca tgtgcaacag gtacaaactc
     3721 aatcggagaa gcatttaaaa ttgtgcaacg cggtgatgca gatgcaatga ttactggtgg
     3781 tacggaagct ccaatcactc atatggcaat tgcaggtttc agtgcaagtc gagcgctttc
     3841 tacaaatgat gacattgaaa cagcatgtcg tccattccaa gaaggtagag acggttttgt
     3901 tatgggtgaa ggtgctggta ttttagtaat cgaatcttta gaatcagcac aagctcgagg
     3961 tgccaatatt tatgctgaga tagttggcta tggtactaca ggtgatgctt atcatattac
     4021 agcgccagct ccagaaggtg aaggcggttc tagagcaatg caagcagcta tggatgatgc
     4081 tggtattgaa cctaaagatg tacaatactt aaatgcccat ggtacaagta ctcctgttgg
     4141 tgacttaaat gaagttaaag ctattaaaaa tacatttggt gaagcagcta aacacttaaa
     4201 agttagctca acaaaatcaa tgactggtca cttacttggt gcaacaggtg gaattgaagc
     4261 aatcttctca gcgctttcaa ttaaagactc taaagtcgca ccgacaatac atgcggtaac
     4321 accagaccca gaatgtgatt tggatattgt tccaaatgaa gcgcaagacc ttgatattac
     4381 ttatgcaatg agtaatagct taggattcgg tggacataac gcagtattag tattcaagaa
     4441 atttgaagca taattataaa aatcttcagt aacgttgttt tagttactga agattttttc
     4501 tgtttcttta tactaagatg agcgacagca caatcgtcat aataaaatat agaatattta
     4561 ttaataataa ggggattatc catgtagaaa caaagtaatg ctcttttttt acctcttgtg
     4621 ggttgaaaaa tggatcatca gagatagact tcttcttttt cgaagatgac atttgatact
     4681 ttaatcttct aaaaccataa cttgtcgcat caaaaatgcc ttcttgtaca agtaaaatca
     4741 aaaatatgct aataaaaata attaatgaaa cataaaacaa tatatttaaa tatgtaatga
     4801 tagtatggct attaaaaacc catataataa acgttaatat tggcgttatt agtgccattc
     4861 caagccattt tttcaacatt tgatcactcc cacttataga aaactcttac gcatagttta
     4921 cattaaaatg agacattgag gaatgatttt ttaatttctg cagctttatt gaaattctaa
     4981 aatcaatcat tcttcattag tttaaagcaa aaaaatattg atatatagta aatattgtat
     5041 atataatatt agttaagatt tcagaaaatt ttgaagggaa tggaaattta gaaatcggaa
     5101 tttgttagag gaggggatta gatggggaaa tat
//
LOCUS       DAPDIM010000115         4956 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000115 DAPDIM010000000
VERSION     DAPDIM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4956
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.119"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..158
                     /locus_tag="RFE25_002708"
     CDS             <1..158
                     /locus_tag="RFE25_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HrcA family transcriptional regulator"
                     /protein_id="HDU2817721.1"
                     /translation="KIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVI
                     QLLNRIW"
     gene            190..816
                     /gene="grpE"
                     /locus_tag="RFE25_002709"
     CDS             190..816
                     /gene="grpE"
                     /locus_tag="RFE25_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDU2817722.1"
                     /translation="MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAI
                     EETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQ
                     AQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEG
                     EAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ"
     gene            885..2717
                     /gene="dnaK"
                     /locus_tag="RFE25_002710"
     CDS             885..2717
                     /gene="dnaK"
                     /locus_tag="RFE25_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDU2817723.1"
                     /translation="MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKN
                     GETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAE
                     SYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDK
                     DEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKEN
                     GVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFE
                     ELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKG
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSK
                     SQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDK
                     NGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNE
                     ADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQ
                     ELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK"
     gene            2853..3992
                     /gene="dnaJ"
                     /locus_tag="RFE25_002711"
     CDS             2853..3992
                     /gene="dnaJ"
                     /locus_tag="RFE25_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDU2817724.1"
                     /translation="MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADE
                     KFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFS
                     SFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPG
                     TSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKT
                     VKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKL
                     NVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDI
                     KVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE"
     gene            3996..4934
                     /gene="prmA"
                     /locus_tag="RFE25_002712"
     CDS             3996..4934
                     /gene="prmA"
                     /locus_tag="RFE25_002712"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDU2817725.1"
                     /translation="MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPED
                     KYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQI
                     IAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTT
                     SMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRR
                     NHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIK
                     EKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE"
BASE COUNT         1932 a          695 c          994 g         1335 t
ORIGIN      
        1 taaaaattgg taatgaaatt gatgacagct taagtgatat ttcaattgta acaagtcaat
       61 atcattttga tgaaacgtta aaaggtcaaa tcgctgtgat tggacctaca gctatgcatt
      121 atcaaaatgt cattcaatta ttaaatagaa tttggtaatg atggattaga aagtattgga
      181 ggacagaaaa tgacaaataa agacgaatca gttgaaaaaa acactgaatc aacagttgaa
      241 gaaacaaaca tcaaacaaaa tattgatgat tcagttgaac aagctgaaga aagtaaaggt
      301 catttacaag atgaagcaat agaagaaacg tctgacgaga atgttattga agaaatagat
      361 ccaaaagatc aaaaaattaa tgaacttcaa caattagcag atgaaaacga agagaaatat
      421 ttaaggctct acgctgagtt tgaaaattat aagcgtagaa ttcaaaaaga aaatgaaata
      481 aataaaacat atcaagcaca acgtgtgtta acagatattt taccagcaat agacaatata
      541 gaacgtgcac ttcaaattga aggtgatgat gagactttta aatctcttca aaaaggtgta
      601 caaatggtgc atgaaagttt gattaacgca ctaaaagata atggtcttga agttattaaa
      661 actgaaggtg aagcatttga tccaaatatt caccaagctg tagttcaaga tgataaccct
      721 gattttgaat ctggcgaaat cactcaagaa ctacaaaaag gatacaagct taaagataga
      781 gtattaagac catcaatggt caaagtaaac caataactta aatttggcga aaagacattg
      841 tttaaaatta aattaattta atgattaaat ggaggaattt tattatgagt aaaattattg
      901 gtatagactt aggtacaaca aattcatgtg taacagtatt agaaggcgat gagccaaaag
      961 taattcaaaa ccctgaaggt tcacgtacaa caccatctgt tgtagctttc aaaaatggag
     1021 aaactcaagt tggtgaagta gctaaacgtc aagctattac aaacccaaac actgttcaat
     1081 ctattaaacg tcatatgggt actgattata aagtagatat tgaaggtaaa tcatacacac
     1141 cacaagaaat ctcagctatg attttacaaa acttaaaaaa tacagctgaa agctatttag
     1201 gtgagaaagt tgacaaagct gtaattacag tacctgcata ctttaacgac gctgaacgtc
     1261 aagcaactaa agatgctggt aaaattgctg gtttagaagt tgagcgtatc attaatgaac
     1321 caacagctgc agcattagca tatggtttag ataaaactga taaagatgaa aaagttcttg
     1381 tttttgactt aggtggcggt acatttgacg tatctatcct agaattaggt gacggtgtat
     1441 tcgaagtact atcaacagcc ggtgacaaca aacttggcgg tgatgatttt gaccaagtaa
     1501 ttattgacta cctagttgca gaattcaaaa aagaaaatgg cgtagactta tctcaagata
     1561 aaatggcatt acaacgtttg aaagatgctg ctgaaaaagc taaaaaagac ttatcaggtg
     1621 tatcacaaac tcaaatctca ttaccattta tctcagctgg tgaaaacggt ccattacact
     1681 tagaagtaaa cttaactcgt tctaaatttg aagaattatc agattcatta attagaagaa
     1741 caatggaacc tacacgccaa gcaatgaaag acgctggctt aacaaactca gatatcgatg
     1801 aagttatctt agttggtgga tcaactcgta ttccagcagt acaagaagct gtcaaaaaag
     1861 aaatcggtaa agaacctaac aaaggtgtaa acccggacga agtagtggca atgggagctg
     1921 caatccaagg tggcgttatc acaggtgacg ttaaagacgt agtattatta gacgtaacac
     1981 cactatcttt aggtattgaa attttaggtg gacgtatgaa tacgttaatt gaacgtaaca
     2041 ctacgattcc tacatctaaa tctcaaatct attcaacagc agtagataat caaccatcag
     2101 tagatgtaca cgtattacaa ggtgaacgtc caatggctgc ggataataaa acacttggta
     2161 gattccaatt gactgatatt ccaccagctg aacgtggtaa acctcaaatt gaagtaacgt
     2221 ttgatatcga taaaaacggt attgtaaatg taactgcaaa agacttaggt acaaataaag
     2281 aacaaagaat tacaattcaa tcaagttctt cattatcaga cgaagaaatc gaccgtatgg
     2341 taaaagatgc tgaagttaac gctgaagcag ataaaaaacg tcgtgaagaa gtagacttaa
     2401 gaaacgaagc tgacagtcta gtattccaag ttgaaaaaac tttaactgat ttaggcgaaa
     2461 atattggtga agaagataaa aaatctgctg aagagaaaaa agacgctctt aaaactgctt
     2521 tagaaggtca agatatagaa gatattaaat ctaaaaaaga agaacttgaa aaagtgattc
     2581 aagaattatc agcaaaagta tatgagcaag cggctcaaca gcaacaacaa gcacaaggtg
     2641 caaatgctgg tcaaaacaac gatagtactg tagaagatgc tgaatttaaa gaagtaaaag
     2701 acgacgacaa aaaataatta aacaatacaa ttagaatgtt gtcatgatct gaaaagtcaa
     2761 agtcaataga acattggctt tggcttttta tttggatagt atgacatatt acgttaaact
     2821 atatgagtta attaagaaaa ggagagatag ctgtggccaa aagagactat tatgaagttt
     2881 taggcattag taaagatgct tcaaaagatg aaatcaaaaa agcgtatcga aagctttcga
     2941 aaaaatatca tccagatatt aacaaagaag aaggtgcaga tgaaaagttt aaagaaattt
     3001 ctgaagccta tgaagtttta agtgatgata ataaacgcgc aagctatgat caatttggac
     3061 atgatggtcc acaaggtttt ggtggacaag gattcaatgg ctctgacttt ggcggtttta
     3121 gtggcttcgg tggcggcggt tttgaagata tctttagctc tttcttcggt ggcggcagac
     3181 aaagagatcc aaatgcaccg caaaaaggtg atgatcttca gtatacaatg acattaacat
     3241 ttgaagaagc ggtatttggt acaacaaaag aaatttcaat ccgtaaagat gtaacatgcg
     3301 aaacatgtca tggtgatggt gcaaagcctg gaacaagtaa aaagacttgt agttactgta
     3361 atggcgctgg tcatgtagct gtagaacaaa acacaatttt aggtagagtt cgtactgaac
     3421 aagtttgtcc taaatgtaat ggaagtggtc aagaatttga agaagcttgt ccaacatgtc
     3481 acggaaaagg tactgaaaat aaaacagtta aattagaagt gaaagtacct gaaggtgtcg
     3541 acaatgaaca acaaattaga ttagctggtg aaggctctcc aggcgtgaat ggaggacctg
     3601 ctggtgattt atacgtagta tttagagtta aaccatctga aacatttaaa cgtgatggtg
     3661 atgatattta ttacaaatta aatgttagct tcccacaagc agctttaggc gatgaaataa
     3721 aaataccaac attaaataat gaagttatgt taacaatccc tgctggtaca caaacaggta
     3781 agcaattccg cttaaaagaa aagggtataa aaaatgttca tggctatgga tacggagatt
     3841 tatatgttga tattaaagta gtaacgccta ctaaattaac agatagacaa aaagaactaa
     3901 tgaaagaatt tgcccaatta aatggtgaag aaattaatga acaaccttcg aattttaaag
     3961 atagagcaaa aagattcttt aagggagaat aaagtatgaa ctggacagag ctttcaatta
     4021 ttattaatca tgaagcagta gaattggcta ccaatatact tgaaaatcat ggatcaaatg
     4081 gtgtcgtgat agaagattca gatgatttaa ttaaccaacc agaagataaa tacggtgaaa
     4141 tttacgcttt gaaaaaagag gattatccag ataagggagt aagattgaaa gcctatttta
     4201 atgaaatgac ttatgatgat aagttgcgac agcaaattaa agatgagtta ttaaatttag
     4261 atgaacttga tcaacataac attcaattca gtgagcaaat tattgcagag acggattggg
     4321 aaaatgaatg gaaaaactat ttccatccat tccgagcgtc gaagaagttc acaatagttc
     4381 ctagttggga aacatatgct aaagaagcgg atgaagagct ttgcattgag ctcgacccag
     4441 gtatggcttt tggaacaggc gatcatccga ctacaagtat gtgtttgaag gcaatagaaa
     4501 catatgtatt gccacagcat tcagtaattg atgttggtac tggctcaggt atattaagta
     4561 ttgcaagtca tctaatcggt gtaaaacgta ttaaagcgtt ggatattgat gaaatggcag
     4621 tgagtgtagc taaagaaaac ttcagaagaa atcattgtga aacgttaatt gaagctgttc
     4681 caggtaactt attgaaagac gaaacagaaa aatttgatat tgtaatagca aatattttag
     4741 cgcatattat tgatgaaatg attgaagatg cttataatac tctaaatgaa ggcggttatt
     4801 ttattacttc tggtattata aaagagaagt atgaaggtat acagtcacat atggagcgtg
     4861 taggttttaa aattatttca gaacaacatg acaatggttg ggtttgtctt gttggccaga
     4921 aagtgagtga ataatgtgca acgttatttc atagac
//
LOCUS       DAPDIM010000116         4901 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000116 DAPDIM010000000
VERSION     DAPDIM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4901
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.120"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..417
                     /locus_tag="RFE25_002713"
     CDS             <1..417
                     /locus_tag="RFE25_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDU2817726.1"
                     /translation="AVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASNDFEKG
                     KNQNHLSDAQVERIIDTYKRKATIDKYSYSATLQEIADNDYNLNIPRYVDTFEEEAPI
                     DLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE"
     gene            410..1633
                     /locus_tag="RFE25_002714"
     CDS             410..1633
                     /locus_tag="RFE25_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDU2817727.1"
                     /translation="MSNTQTKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSE
                     NYTNKGIPFLRSQNIRNGKLNLNDLVYISKDIDDEMKNSRTYYGDVLLNITGASIGRT
                     AINSIVETHANLNQHVCIIRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFK
                     EIANLKIFTPTIFEEQQKIGQFFSKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRF
                     KDENGEDYPDWENSKIEKYLKERNERSDKGQMLSVTINSGIIKFSELDRKDNSSKDKS
                     NYKVVRKNDIAYNSMRMWQGASGKSNYNGIVSPAYTVLYPTQNTSSLFIGYKFKTHRM
                     IHKFKINSQGLTSDTWNLKYKQLKNINIDIPVLEEQEKIGDFFKKMDILISKQKMKIE
                     ILEKEKQSFLQKMFL"
     gene            2016..2699
                     /locus_tag="RFE25_002715"
     CDS             2016..2699
                     /locus_tag="RFE25_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL11"
                     /protein_id="HDU2817728.1"
                     /translation="MKLKNIAKASLALGILTTGMITTTAQPVKASTLEVRSQATQDLS
                     EYYKGRGFELTNVTGYKYGNKVTFIDNSQQIDVTLTGNEKLTVKDDDEVSNVDVFVVR
                     EGSDKSAITTSIGGITKTNGTQHKDTVQNVNLSVSKSTGQHTTSVTSEYYSIYKEEIS
                     LKELDFKLRKHLIDKHDLYKTEPKDSKIRITMKNGGYYTFELNKKLQPHRMGDTIDSR
                     NIEKIEVNL"
     gene            2721..4208
                     /locus_tag="RFE25_002716"
     CDS             2721..4208
                     /locus_tag="RFE25_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKLRK protein"
                     /protein_id="HDU2817729.1"
                     /translation="MRENFKLRKMKVGLVSVAITMLYIMTNGQAEASETNQKVSTNQE
                     SKAVSQTEQNSKETKAAESSKNFVNLDPIKPGAQKVTGTTLPNHIILLNIDGKSADSV
                     EGGYGDFITANDKGEFEYPLNNRKIVHNQEIEVSSSSPDLGDDEEDEEVEESSTEKAG
                     AEEESTDAKATYTTPRYEKAYEIPKEQLKEKDGHHQVFIEPITEGSGIIKGHTSVKGK
                     VALSINNKFINFEERAKGGISKEDTKASSDGVWMPINEKGYFDFDFKKNPFDNLELKK
                     NDEISLTFAPDDEDEALKSLIFKTKVTSLEDIDKAETKYDHTKVEKVKVLKDVKEDIH
                     VDEIYGSLYHTEKGKGILDKQGTKEITGKTKFANAVVKVYSDLGDAQLFPDIQVDENG
                     KFSFDAEKAGFRLQNGETLNFAVVKPITGDLLHQGFVSKYIDVYESPEEKKEREFEEK
                     LENTPAYHKLHGDKIVGYDVQGNPSTWFYPLGEKKVERTTPKLEK"
     gene            complement(4317..4625)
                     /gene="spn"
                     /locus_tag="RFE25_002717"
     CDS             complement(4317..4625)
                     /gene="spn"
                     /locus_tag="RFE25_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myeloperoxidase inhibitor SPIN"
                     /protein_id="HDU2817730.1"
                     /translation="MKFKKVLVATAMVGVLATGVVGYGNQADAKVYSQNGLVLHDDAN
                     FLEHELSYIDVLLDKNADQATKDNLRSYFADKGLHSIKDIINKAKQDGFDVSKYEHVK
                     "
BASE COUNT         2004 a          614 c          855 g         1428 t
ORIGIN      
        1 gccgtgattg ggttaccagc caatattttc tatgggacaa gtattccaac atgtatttta
       61 gtatttaaaa aatgtcgcca acaagacgac aacgtactat ttatcgatgc atccaatgat
      121 tttgaaaaag gaaaaaatca aaaccattta agcgatgccc aagtcgaacg tattatagac
      181 acatataagc gtaaagcaac gattgataaa tatagctaca gcgcgacatt acaagagatc
      241 gccgataacg attacaactt aaacataccg cgatatgttg atacattcga agaagaagca
      301 ccaattgatt tagatcaagt ccaacaagat ttgaaaaata tcgacaaaga aatcgcagaa
      361 attgaacaag aaatcaatgc atacctgaaa gaacttgggg tgttgaaaga tgagtaatac
      421 acaaacgaaa aatgtgccag agttgagatt cccaggattt gagggcgaat gggaagagaa
      481 gaagttaggg aatcttacta ccaaaatagg tagtggaaag actcccaaag gtggaagtga
      541 aaactataca aacaaaggca taccattttt aaggagtcaa aatattagaa atggtaaatt
      601 aaatcttaat gacttagttt atattagtaa agatatagat gatgagatga aaaatagtag
      661 aacgtactat ggtgatgttc ttttaaatat tacaggagca tcaataggta gaacagccat
      721 taattcgata gttgaaacgc atgctaattt aaatcaacat gtatgtatta ttagattaaa
      781 aaaagagtat tattataatt tttttggaca gtatctatta tcaagaaaag gtaaaagaaa
      841 aattttcctt gcacaaagtg gaggtagtcg agaaggacta aacttcaaag aaattgctaa
      901 tttaaaaatc ttcaccccaa ctatatttga agaacaacaa aaaataggac aattcttcag
      961 caaactcgac cgacaaattg aattagaaga acaaaagctt gaattacttc aacaacagaa
     1021 aaaaggctat atgcagaaaa ttttctcaca ggaactgcga ttcaaagatg agaatggtga
     1081 agattatcca gattgggaaa atagcaaaat agaaaaatat ttaaaagaga gaaacgaacg
     1141 ttctgacaaa gggcaaatgc tttcagtaac tataaatagt ggcattataa aatttagtga
     1201 attggataga aaagataatt caagtaaaga taaaagtaat tataaagtag ttaggaaaaa
     1261 tgatattgca tataattcta tgagaatgtg gcaaggggct agtggtaaat caaattataa
     1321 tgggattgtt agccctgcat atactgtgct ttatccaaca caaaatacta gctcattatt
     1381 tattggatat aagtttaaaa cacatagaat gattcataaa tttaaaatta attcacaagg
     1441 attaacatca gatacatgga acttaaaata taaacaatta aaaaatataa atatagatat
     1501 acctgtattg gaggaacaag aaaagatagg tgatttcttt aaaaaaatgg atatattgat
     1561 aagtaaacag aaaatgaaaa ttgaaatatt agaaaaagag aaacaatcct ttttacaaaa
     1621 aatgttctta taactttgat aaatacatag attgcataag aataaaattt gtataattta
     1681 acataaaagt tgtaaaagta aagtgaatta aaaacgaaca ttaaatttag gcactgtgaa
     1741 agcgcagtgt cttttttgtg tcgaaattgt gtacagaata agtagttaaa taaagattaa
     1801 gttgagataa agtgttattc gtaaataaaa gagagtagat cgataggaat tgaatgatat
     1861 tagttaacta tttattaaat tacttaataa tgattaattt ttagttaaag taagtttaat
     1921 gtgaagcacg accattgctc attataatga atgaggattg ttcgtattgc gtaatagaat
     1981 aaatcaaata gactaaaaat tgggagcata gaattatgaa attaaaaaat attgctaaag
     2041 caagtttagc actagggatt ttaacaacag gtatgattac aactactgct cagccagtaa
     2101 aagcaagtac attagaggtt agatcacaag ctactcaaga cttgagtgaa tattataaag
     2161 ggagaggatt tgaattaaca aatgtaacag gatataaata cggaaataaa gttacattta
     2221 tagataattc tcaacaaatt gatgttacat tgacaggaaa tgaaaaatta actgttaaag
     2281 atgatgacga agtttctaat gttgacgtgt ttgtagtaag agaaggtagt gacaaatcag
     2341 ctatcacaac atcgattggt ggaattacaa agacaaatgg gactcaacat aaagatactg
     2401 ttcaaaacgt taatttgtca gtttctaaga gtacaggtca acacactact tctgtgactt
     2461 cagaatacta tagcatctat aaagaagaaa tctcattaaa agaacttgat tttaaattaa
     2521 gaaagcattt aattgataaa catgatcttt ataagacaga acctaaagac agtaaaatta
     2581 gaattactat gaaaaacggt ggctattata catttgaatt aaataaaaaa ttacagcctc
     2641 atcgcatggg tgatacgatt gatagtagaa atatagagaa aattgaagtg aatttataat
     2701 aatattcgag ggagtatatc atgagagaaa attttaaatt acgtaaaatg aaagtcggtt
     2761 tagtatcagt tgcaattact atgttatata tcatgacaaa cggacaagct gaagcatctg
     2821 aaactaatca gaaggtaagt acaaatcaag aatcaaaagc tgtttcgcag actgaacaaa
     2881 attccaaaga aacaaaagcg gcagagtctt ctaaaaactt tgtaaattta gatcctatca
     2941 aaccaggagc tcaaaaagta acaggtacta cattaccgaa tcatattatt ttacttaata
     3001 tagatggtaa aagtgctgat tcagttgaag gaggatatgg tgattttata actgcaaatg
     3061 acaaaggaga gtttgagtat cctttaaata atcgtaaaat tgtccataac caagaaattg
     3121 aggtatcatc atcaagccct gatttaggtg acgatgaaga ggatgaagaa gtagaagaat
     3181 cttcaactga aaaagctggt gctgaggaag aaagtacaga tgctaaagct acatatacaa
     3241 caccacgata tgaaaaagcg tatgaaatac cgaaagaaca actaaaagaa aaagatggac
     3301 accaccaagt tttcatcgaa ccaattactg aaggttcagg tattattaaa ggtcatacgt
     3361 ctgtaaaagg taaagttgct ctatctatta ataataaatt tattaatttt gaagaaagag
     3421 ctaaaggtgg aattagtaaa gaagatacta aagctagttc cgatggtgtt tggatgccta
     3481 ttaatgaaaa aggatatttt gattttgatt tcaaaaaaaa tccttttgat aacttagagt
     3541 taaagaaaaa tgatgaaatc tcattaacat ttgcacctga tgatgaagat gaagcattga
     3601 agtcattaat tttcaaaact aaagtaacga gcttagaaga tatcgataaa gcagaaacaa
     3661 aatatgacca tactaaagtg gaaaaagtaa aagtattgaa agatgttaaa gaagatatac
     3721 atgtagatga aatttacgga agcttatatc atacagaaaa aggtaaaggt attcttgata
     3781 aacaaggaac taaagagatt acagggaaga ctaaattcgc gaatgcagta gtgaaagtat
     3841 attctgactt aggtgatgcg caattgttcc ctgatattca agtagatgaa aatggtaaat
     3901 ttagctttga tgctgaaaaa gctggtttca gattgcaaaa tggagaaaca ttgaattttg
     3961 cagtagttaa acctattact ggtgacctat tacatcaagg atttgtctct aaatatattg
     4021 atgtatatga atctccggaa gaaaagaaag aacgtgaatt tgaagaaaaa cttgaaaaca
     4081 cgcctgcata tcataaatta catggtgata aaattgtagg atatgatgtt caaggtaatc
     4141 catcaacttg gttctatcca ttaggtgaaa agaaagttga acgtacaaca cctaaattag
     4201 aaaaataatt aataaaataa aacagcttaa tgatgtaatg aaattagtga gttaatcact
     4261 gacttcaacg tcattgagct gttttttatt tgcttcgtta caaagcatta ttgaatttat
     4321 tttacgtgtt catattttga aacatcaaag ccgtcttgct tagctttgtt gataatgtct
     4381 ttgattgaat gtagtccttt atcggcgaag tatgatctta agttgtcttt tgtagcttgg
     4441 tcagcattct tatctaataa cacatcgata tagcttaatt catgttctaa gaagtttgcg
     4501 tcatcatgta gtacgagtcc attttgagaa taaactttcg catctgcttg attaccatat
     4561 ccaacaacgc cagttgctaa tacacctacc attgccgtag ctactaaaac ctttttaaat
     4621 ttcatatcta tcactcctct aaaaattgta actctatcat aacactgaat attaagaaaa
     4681 ttacgtttat taagtcgatt taataatttt taataaatag ttaaactgac aaatattgct
     4741 taaatgcaat taatctttaa aacggtgttt atggattttt cctactaaaa ccttgatttc
     4801 aaaaagggtt taaatcaaat gaaacaataa taaaaaataa tgcaacataa taataagtac
     4861 aaatttaatt aagaaattaa attgattgta tatgtatatt t
//
LOCUS       DAPDIM010000117         4838 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000117 DAPDIM010000000
VERSION     DAPDIM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4838
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.121"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            77..949
                     /gene="dprA"
                     /locus_tag="RFE25_002718"
     CDS             77..949
                     /gene="dprA"
                     /locus_tag="RFE25_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDU2817731.1"
                     /translation="MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEW
                     VNREENVLLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLF
                     YKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
                     IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNR
                     IISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAK
                     VVLNANDIFEDYYI"
     gene            1123..3198
                     /gene="topA"
                     /locus_tag="RFE25_002719"
     CDS             1123..3198
                     /gene="topA"
                     /locus_tag="RFE25_002719"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDU2817732.1"
                     /translation="MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQM
                     GVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILEL
                     EDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKV
                     KKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPF
                     KLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKT
                     MMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKA
                     SGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVS
                     LDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPA
                     QHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEI
                     VHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEME
                     KIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCND
                     GDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSN
                     CDYKEAAQK"
     gene            3354..4661
                     /gene="trmFO"
                     /locus_tag="RFE25_002720"
     CDS             3354..4661
                     /gene="trmFO"
                     /locus_tag="RFE25_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HDU2817733.1"
                     /translation="MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHT
                     DKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFS
                     GYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDA
                     AAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEK
                     EKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNI
                     VGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQ
                     FAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKN
                     FQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL"
BASE COUNT         1856 a          701 c          895 g         1386 t
ORIGIN      
        1 gacaatgttt ttgtattaga aatgtaaaac aaaaatagaa tatgattttg tatgattaca
       61 aaaaggagtt gatttattga ttaaactatt tttgcttaag ttatactggg cacacttttc
      121 gactaaacaa attcatcaat ttttaatggc atatcctaat gtaattaaag aggagggaag
      181 aaaaaaagat agttatttat gtgaatgggt gaatagggaa gaaaatgttc ttttattacg
      241 taaatactat gcttttataa aacttgatca taacgatatt attaaagaac tgcagaaatt
      301 aaaagtaagt tacattacat atatggattc tgaataccca gtgctattaa aagaaatata
      361 tcaatttcca ttacttcttt tctataaagg gaacatcaaa ttaataaata atatgcatca
      421 tttggcagta gtaggtgcaa gagattctac aagttatacc caacagtctt tagaattttt
      481 attatcaaat gataaaagca aatatttaac aattgtttcc ggccttgctc aaggagctga
      541 tgcaatggca catcaaatag ctttaaaata caatctccct acaattgcag ttttagcctt
      601 tggccatcaa acacattatc ccaaaagtac attagcatta agaaataaaa tagaagaaaa
      661 aggtttagtt atatccgaat atccaccaca tacaccaatt gctaaatata gatttcctga
      721 gcgcaataga attatcagcg gtttgtcaaa aggggtttta attactgagg ctaaggaaca
      781 aagtggcagt cacatcacga tagattttgc attagagcaa aatagaaatg tttatgtttt
      841 acctggatct atgtttaatc ctatgacaaa aggtaattta ttacgtatcc aagaaggtgc
      901 taaggtagta ttaaacgcta atgatatatt tgaagactac tatatttaaa actaaaaata
      961 acgagttgct tcatatttct tttgttaccc tttgtaattt attttttaat aaaatctata
     1021 aaaaatagac agggaaaatg atttgtttag atataaaacg ttgacaaaag caaaattaag
     1081 cgtttatcat ttatctttag taattagatt agcgaggggg aaatgacatt ggcagataat
     1141 ttagtcattg ttgaatcgcc tgcaaaagca aaaaccattg aaaagtattt aggtaagaaa
     1201 tataaagtta tagcttcaat gggacacgtc agagacttac caagaagtca aatgggtgtc
     1261 gacactgaag ataattacga accaaaatat ataacaatac gcggaaaagg tcctgttgta
     1321 aaagaattga aaaaacatgc aaaaaaagcg aaaaacgtct ttctcgcaag tgaccccgac
     1381 cgtgaaggtg aagcaattgc ttggcattta tcaaaaattt tagagcttga agattctaaa
     1441 gaaaatcgcg ttgttttcaa cgaaataact aaagacgctg ttaaagaaag ttttaaaaat
     1501 cctagagaaa ttgaaatgaa cttagtcgat gcacaacaag cgcgtcgaat attagataga
     1561 ttggttggct ataacatctc gccagttcta tggaaaaaag tgaaaaaagg tttgtcagcg
     1621 ggtcgagttc aatctgttgc acttcgttta gtcattgacc gtgaaaatga aattcgaaac
     1681 tttaaaccag aagaatattg gactattgaa ggagaattta gatacaaaaa atcaaaattc
     1741 aatgctaaat tccttcatta taaaaataaa ccttttaaat taaaaacgaa aaaagatgtt
     1801 gagaaaatta cagctgcact agatggagat caattcgaaa ttacaaacgt gactaaaaaa
     1861 gaaaaaacgc gtaatccagc aaacccattt acaacttcta cattacaaca agaggcggca
     1921 cgtaaattaa actttaaagc aagaaaaaca atgatggtcg cacaacaatt atatgaaggt
     1981 atagatttga aaaaacaagg tacgattggt ttaataacat atatgagaac cgattctaca
     2041 cgtatttcag atactgccaa agctgaagca aaacagtata taactgataa atacggtgaa
     2101 tcttacactt ctaaacgtaa agcatcaggg aaacaaggtg accaagatgc ccatgaggct
     2161 attagacctt caagtactat gcgtacgcca gatgatatga agtcattttt gacgaaagac
     2221 caataccgat tatacaaatt aatttgggaa cgatttgttg ctagtcaaat ggctccagca
     2281 atacttgata cagtctcatt agacataaca caaggtgaca ttaaatttag agcgaatggt
     2341 caaacaatca agtttaaagg atttatgaca ctttatgtag aaactaaaga tgatagtgat
     2401 agcgaaaagg aaaataaact gcctaaatta gagcaaggtg ataaagtcac agcaactcaa
     2461 attgaaccag ctcaacacta tacacaacca cctccaagat atactgaggc gagattagta
     2521 aaaacactag aagaattgaa aattgggcga ccatcaactt atgcaccgac aatagatacg
     2581 attcaaaagc gtaactatgt caaattagaa agtaagcgtt ttgttcctac tgagttggga
     2641 gaaatagttc atgaacaagt gaaagaatac ttcccagaga ttattgatgt ggaattcaca
     2701 gtgaatatgg aaacgttact tgataagatt gcagaaggcg acattacatg gagaaaagta
     2761 atagacggtt tctttagtag ctttaaacaa gatgttgaac gtgctgaaga agagatggaa
     2821 aagattgaaa tcaaagatga gccagccggt gaagactgtg aagtttgtgg ttctcctatg
     2881 gttataaaaa tgggacgcta tggtaagttc atggcttgct caaacttccc ggattgtcgt
     2941 aatacaaaag cgatagttaa gtctattggt gttaaatgtc caaaatgtaa tgatggtgac
     3001 gtcgtagaaa gaaaatctaa aaagaatcgt gtcttttatg gatgttcgaa atatcctgaa
     3061 tgcgacttta tctcttggga taagccgatt ggaagagatt gtccaaaatg taaccaatat
     3121 cttgttgaaa ataaaaaagg caagacaaca caagtaatat gttcaaattg cgattataaa
     3181 gaggcagcgc agaaataata tttttattcc ctagagacat tttaagattg ttaaatagaa
     3241 tcattagtga atcttatttt aaagatagta atggattaat ctaaataagt gcggataata
     3301 taaacataac aacataatta aaagacataa atgacaataa aaggagtata gaaatgactc
     3361 aaactgtaaa tgtaataggt gctggtcttg ccggttcaga agcggcatat caattagctg
     3421 aaagaggaat taaagttaat ctaatagaga tgagacctgt taaacaaaca ccagcgcacc
     3481 atactgataa atttgcggaa cttgtatgtt ccaattcatt acgcggaaat gctttaacta
     3541 atggtgtggg tgttttaaaa gaagaaatga gaagattgaa ttctataatt attgaagcgg
     3601 ctgataaggc acgagttcca gctggtggtg cattagcagt tgatagacac gatttttcag
     3661 gttatattac tgaaacactt aaaaatcatg aaaatatcac agttattaat gaagaaatta
     3721 atgccattcc agatggatac acaattatcg caacaggacc acttactaca gaaacccttg
     3781 cgcaagaaat agtggacatt actggtaaag atcaacttta tttctatgat gcagctgctc
     3841 caattattga aaaagaatct attgatatgg ataaagttta cttaaagtcc cgttatgata
     3901 aaggtgaagc tgcatattta aactgtccta tgactgagga tgaatttaat cgcttttatg
     3961 atgcagtatt agaagctgaa gttgcacctg taaattcatt tgaaaaagaa aaatatttcg
     4021 agggttgtat gccttttgaa gtaatggcag aacgcgggcg caagacatta ctatttggac
     4081 caatgaaacc agtaggatta gaagatccaa agactgggaa acgtccttat gcagtggttc
     4141 aattaagaca agatgacgct gctggcacac tctacaatat tgtcggcttc caaacacatt
     4201 taaaatgggg agctcaaaaa gaagtcatta aattaattcc aggtttagag aatgttgata
     4261 ttgttagata tggtgtgatg catagaaata ccttcattaa ctcaccggac gtattaaacg
     4321 aaaaatatga attgatttca caaccaaaca tacagtttgc gggacaaatg actggtgttg
     4381 aaggttatgt agaaagcgca gctagcggct tagttgcagg tatcaatctt gcgcataaaa
     4441 tattaggcaa aggtgaggta gtatttccga gagaaactat gattggaagt atggcttact
     4501 atatttctca tgctaaaaac aataagaatt tccaacctat gaatgctaac ttcgggttat
     4561 taccatcttt agaaactaga attaaagata aaaaagaacg ctatgaagca caagctaata
     4621 gagctttgga ttacttagaa aatttcaaaa aaactttata aaatagttag aaagactaga
     4681 tatgctattc attcttaagt catcaacgag taagtaatga ctttctaaat ggaaaatact
     4741 tatcctagtc tttttaattt tggaattgtt acgtatttct gacaatttag aattcgtatt
     4801 caaaaaaata tctaaataaa taacacgcaa taagttga
//
LOCUS       DAPDIM010000118         4813 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000118 DAPDIM010000000
VERSION     DAPDIM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4813
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.122"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(140..1948)
                     /locus_tag="RFE25_002721"
     CDS             complement(140..1948)
                     /locus_tag="RFE25_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDU2817734.1"
                     /translation="MHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVL
                     LSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGK
                     FGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQ
                     ITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASE
                     LASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVF
                     TSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHRAFDQAVELAN
                     KSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQ
                     SIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFV
                     RDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKI
                     ESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGF
                     IALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS"
     gene            2080..2472
                     /locus_tag="RFE25_002722"
     CDS             2080..2472
                     /locus_tag="RFE25_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(deoxy)nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="HDU2817735.1"
                     /translation="MKKVINVVGAIIFSDNKILCAQRSEEMSLPLMWEFPGGKIEKNE
                     TEKEALIREIREEMKCDLIVGDKVITTEHEYDFGIVKLTTYKCTLNKELPTLTEHKSI
                     EWLSINELDKLNWAPADIPAVNKIMTEG"
     gene            2474..>4813
                     /locus_tag="RFE25_002723"
     CDS             2474..>4813
                     /locus_tag="RFE25_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDU2817736.1"
                     /translation="MSRLLNDFNQSLKKGFIDKDISHKGNYTPKLLVNNKNEKVLSTI
                     IDELQKCETFYFSVAFITESGLASLKAQLLDLSNKGVKGKILTSNYLGFNSPKMYGEL
                     LKLKNVEVRLTDIAGFHAKGYIFEHKDYSSMVIGSSNLTSNALKVNYEHNVLLSTMKN
                     GDLVDSVKNEFELLWQKSTPLTEQWINSYKESFEYRSLEKLAEVEQTQMLLADKVKKS
                     VEIVPNLMQAEALRSLKAIRDKTKDKALIISATGTGKTILCALDVREVNPNKFLFIVH
                     NEGILNRAKEEFKKVLPIKNDSDFGLLTGKHRDVDAKYLFATIQTLSRDDNFKQFDEN
                     EFDYIVFDEAHRSAASTYQRVFNYFKPKFMLGMTATPERSDELSIFELFDYNIAYEIR
                     LQAALESDILCPFHYFGVTDYVHQGIKEDDVTKLRYLTSDERVNYIIQKTDYYGYSGE
                     ILQGLIFVSSKKEAYDLADKLSSKGIKSVALTGDDSVNYRQIVIEKLKEGKINYIITV
                     DLFNEGIDIPEVNQVVMLRPTESSIIFIQQLGRGLRKSANKEYVTVIDFIGNYKTNYL
                     IPIALSGDQSQNKDNYKKFLTNNDSINGVSTINFEEVAKKQIYNSLDAVSLNQNKLIL
                     KAYEEVENRLGHMPLLMDFIQQHSIDPSVIFSKFSNYYEFLLRYKKIDALLTENESKN
                     LVFFSRQIAPGLKKIDSLVLEELLKNELTYDELKNKMLNEVKDITEDDIDTSLRILDF
                     SFYNAGIEKIYGSPIIECNERMIRLSDAFTNALSNQTFKI"
BASE COUNT         1784 a          635 c          808 g         1586 t
ORIGIN      
        1 gaaaattaat tttctaatat acttttgaaa aattattaca aattagcccc ttcaaaacgc
       61 gaaaacataa ggattctagt ttcaaaaggg ctgataagta taaaatgaaa tgtaatattt
      121 cgatgtataa aatttttaat tagctaaaaa tcatcgcatt aattttttga gctacatcat
      181 caaaatccgg acattttaac gacacatata atttaatttt aggttcagta ccagaaggac
      241 gtaaagcgat aaatccttcg tcaaataaga cacgaataac atttgattta gaagaattaa
      301 tctgtgacgt tgtatcttta tccaaatgat aaacctcgct agttaaataa tcttcaattg
      361 ctttcacttt cagtccttga atctcttgcg gtggatttga acggaaatgt gtcataattg
      421 attcaatttt tttcttacct tctaatcctt ctagcgtatg cgagaataat gtatcctcat
      481 gtctaccaac agtttgataa atctgttcta attcatcttt caatgttttg ccatataatt
      541 ttaactcaga agcgtatttt ataatgagtg gcacaatttg tacggcatct ttatcacgta
      601 caaaaggctc tgatagaaaa ccgtaactct cttcaaatgc gaaaatcata ttttgatgat
      661 catccagttg tcttatttcc tgagcaataa atttaaagcc cgtcagtacc tctttgtatt
      721 taacattatt atagcgtgct aatgactttg ttaactcact acttacaata gattgaatca
      781 ttaagcggtg acgtaattga gacgtttgtt gaatacgata attaagtaac agcgcaccaa
      841 tttggttgcc attaaaatat gtgatatgac catgtgcatc acgttcagca ataccaagtc
      901 gatctgcatc tgggtcagtt gatattaata agtctgcatg acttttattt gcaagttcga
      961 ctgcttgatc aaaagcgcga tgatcttcag gattagcact ttgaactgaa ctaaaattcg
     1021 gatcaggttt acattgtgca tctacaagat taaattgatt gaaattcaaa gattttaata
     1081 actcaggtac aattggaaca cttgtaccat gcaaactagt gaacacaact tgtaaatcag
     1141 atttaggaat atagccaatc atattttgaa tgtgtttcat atagtcatca gttacagatt
     1201 tcggaaaagg tttgatataa gatgtatttt gttttgaaat aggtatatca atctgtaatg
     1261 gatcgccaac ttcttcgata taacgacttg caagctcaga tgcatcagtc gataattgcg
     1321 cgccatcaga accatatact ttaatgccgt tatagtcttt cggattatga cttgctgtaa
     1381 tcataatgcc ggcagtagta ttaagattgc gaaccgcgaa cgataattcc ggtgtcgttt
     1441 tatatgtatc aggtaaataa actgttattt gatggtttgc taatacatta gcaataattt
     1501 gggcgaattc agttgaaaga tgtctaatat cataatgaat gactattgtt ggactgtttg
     1561 tttgggcatt taaataacgc gctaaaccta atgccaattt ttcaatagta aacttattaa
     1621 gtcgaccttc accaagaccg aattttccgc gtatacccgc agtaccaaat gttaatttac
     1681 tttcaaaacc ttctcgctgt tcaatgtcag attgctgctc ataaaaatgt ttaactaaac
     1741 tatcattagc tctttctatc cataattctt tatccattgt tgctaaacat cctttcaaaa
     1801 tctcagttag acttaataaa acatgaaaac taaagccctt acatttatgt aatgaattat
     1861 aaagaaatac gccccaaaag taaaaaaaca cagccccaag acaatacttt tcacaagtat
     1921 tatataatag atgtgtatga aaatgcatgg agtagatgta agagtgatat atcatgcagg
     1981 aaattgtaaa atattaattt ttaatattga tttatatata gttttgtaat ttttgataga
     2041 ataacaatta agatgatttt aaattgaagg gtgagtctta tgaaaaaagt aatcaatgta
     2101 gtaggagcta ttattttttc tgataacaaa attctttgtg cacagagaag tgaagaaatg
     2161 agtctacctt taatgtggga atttcctggc ggtaagattg aaaagaatga aactgaaaaa
     2221 gaagctttga ttagagaaat tagagaagaa atgaaatgtg atctaattgt tggagacaaa
     2281 gtcataacta cagaacatga atatgatttt ggcattgtta agttaacaac atacaaatgt
     2341 actttaaaca aagagttacc aactttaact gaacataaga gtattgaatg gttgtcaata
     2401 aacgaacttg ataaattaaa ttgggcccca gcggatatac cagccgttaa taaaattatg
     2461 actgagggat aatatgagta gattactaaa tgatttcaat caatctttaa aaaaaggttt
     2521 tatagacaaa gatatttctc ataaagggaa ttatacaccg aagcttttag taaataataa
     2581 aaatgaaaaa gtcctttcaa caattataga tgaacttcaa aaatgtgaaa cgttctattt
     2641 ttctgtagct tttataacag aaagcggatt agccagctta aaggctcaac tattagattt
     2701 aagcaataag ggtgttaaag ggaaaatatt aacatctaat tacttaggat ttaatagtcc
     2761 taaaatgtat ggagaattac ttaaattaaa aaatgtagag gtaagattaa ctgatattgc
     2821 tggattccat gccaaaggat atatttttga acataaggat tatagttcta tggtaatagg
     2881 aagctctaat ttaacatcta atgcgttaaa ggttaattat gagcataatg ttttactgtc
     2941 tactatgaaa aatggtgatt tagttgatag tgtaaaaaat gaatttgaat tgttatggca
     3001 aaagagtacc ccactgactg agcaatggat taattcatat aaagaatcat ttgagtaccg
     3061 ttccttagaa aaattagcgg aggttgaaca aactcaaatg ctgctagctg ataaggtgaa
     3121 aaaatcagtg gaaattgtac ccaatttaat gcaagcagaa gcattaaggt cattaaaagc
     3181 tattagggat aaaaccaaag ataaggcgtt aataatatct gcaactggta caggtaaaac
     3241 gattttatgt gcattagatg ttagagaagt aaaccctaat aaatttttat ttattgttca
     3301 taatgagggg attttaaata gagctaagga agaatttaaa aaagtattac ctataaaaaa
     3361 tgatagtgat tttggattgt tgacaggaaa acatagagat gtcgatgcca aatatttatt
     3421 tgcaaccatt caaacattat ctagagatga taattttaag caatttgatg aaaatgaatt
     3481 tgattatatt gtttttgatg aagcacatcg ttctgctgca tctacttatc aacgagtatt
     3541 taactacttc aaacctaagt tcatgctggg aatgactgct acaccagaaa gatcagatga
     3601 attaagtata tttgaactgt ttgattataa tattgcatat gaaataaggt tacaagcagc
     3661 gttagaaagt gatattttat gtccatttca ttattttggt gtgactgatt atgtacatca
     3721 aggtattaaa gaagatgatg taactaaact gagatattta acttctgatg aaagagttaa
     3781 ttatattatt caaaagacag attactatgg atattcaggt gaaattttac aaggattaat
     3841 ttttgtgagt agcaaaaaag aagcttatga tttagcggat aaactaagtt caaaagggat
     3901 taaaagtgtt gctttaacag gagatgatag tgttaattat cgccaaattg taatagaaaa
     3961 attaaaagaa ggtaagatta actatattat aactgtagat ctttttaacg aaggtattga
     4021 tattccagaa gtcaatcaag ttgtaatgtt gagaccaaca gagtctagta ttatattcat
     4081 tcagcaactt ggtagaggat taagaaaaag tgcaaataaa gagtatgtta ctgtaattga
     4141 ttttattggt aattataaga ccaattattt aattccgatt gcgctttctg gggatcaatc
     4201 gcaaaataaa gataattata agaagttttt aacgaataac gattcgatta atggagtatc
     4261 tacaattaat tttgaagaag ttgctaaaaa acagatttac aattcattgg atgcagtatc
     4321 attgaatcaa aataaattaa tattaaaagc ttatgaagaa gttgaaaata gattgggaca
     4381 catgccgtta ctaatggatt ttatacaaca acattctata gatccaagcg ttatattttc
     4441 taaatttagt aattattacg aatttttatt aaggtataaa aaaatagatg ctttattgac
     4501 ggaaaatgaa tctaaaaatc tggttttctt ttcaagacaa atagcacctg gattgaaaaa
     4561 aatcgatagt ttagttttag aagaactttt aaaaaatgaa ttaacatatg atgaattaaa
     4621 aaataaaatg ttgaacgaag ttaaggatat aacagaagat gatatagata cttcattaag
     4681 aattttagat ttttcatttt acaacgcagg aattgaaaaa atctatggaa gtcccattat
     4741 agaatgtaat gaaagaatga taagactaag cgatgcattt actaatgctc taagtaatca
     4801 aacatttaaa ata
//
LOCUS       DAPDIM010000119         4599 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000119 DAPDIM010000000
VERSION     DAPDIM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4599
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.124"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(155..403)
                     /locus_tag="RFE25_002724"
     CDS             complement(155..403)
                     /locus_tag="RFE25_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDU2817737.1"
                     /translation="MAKYTIVDMDTCIACGACGAAAPDIYDYDDEGIAFVILDDNQGT
                     AEVPEELYEDMEDAIDGCPTDSIKIADESFDGDALKFE"
     gene            511..1464
                     /locus_tag="RFE25_002725"
     CDS             511..1464
                     /locus_tag="RFE25_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2817738.1"
                     /translation="MQHIIKTALQQTFNYKTNKSIYNILVGKKSHQTFFDACSQQQLS
                     LYHSLPLLKYPSFELFLEKINEFNAEMEIMLHPRYTFESMGQTFQAIQLLVQTMSNTK
                     QHVFHFVPISQNNKIQETVKIVYNYIKENQLQIDFENELHNLFKAITLKGPCYLHYYL
                     QGYDEPMYTRQQVSLIEKLSQQQLFEYEMNNLVTMMFELESGEYTILSKIIMKPTLLN
                     QTYITYTKLLEQFTMEDIAAQQQVKINTIEDHVLEILIKGYMSNYDDYVELEDQLQFL
                     NFYQQHRGERLKFYKEQFDTLSYFQLKVLIVGFERGDLNVA"
     gene            1454..2833
                     /locus_tag="RFE25_002726"
     CDS             1454..2833
                     /locus_tag="RFE25_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDU2817739.1"
                     /translation="MLHDILRNKFGFENFKPGQQEIIESIMSQQHTLGILPTGSGKSL
                     CYQIPTYLSGKPTLIISPLISLMDDQVMQLKINGEKRVTCIHSGMDEIEKKHNIKCLL
                     HSRFIFLSPEFLLQPSNFKLISMIDFGMIVLDEAHCLSEWGYDFRPHYALIGKVTKHF
                     KEAVVLALTATAPPHLQDDLTEMLAIQFNVIKTTMNRPNISFKHLNFHDDEDKIEWLL
                     PFLQQSGPTIIYVSSKKMCLNLAQLIYDSGFLTGIYHGDMNYQERHTVQQQFLNNDIP
                     IIVATSAFGMGINKKDIRTIIHFHLSTSPSNYIQEIGRAGRDGELSQAISLFQPDDKY
                     ILETLLFADMITEEDVQNFEIGEFLAPDKQDVLTTLHSFYSIGALKQIFKQSFKRKQL
                     GFFRMIGYCKLDQCRRKYLLEFFGEYPPAQDRCCDNDSNITDIVILNKKKVIRSIGFD
                     EKLQNLFLR"
     gene            2986..4446
                     /gene="ebpS"
                     /locus_tag="RFE25_002727"
     CDS             2986..4446
                     /gene="ebpS"
                     /locus_tag="RFE25_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elastin-binding protein EbpS"
                     /protein_id="HDU2817740.1"
                     /translation="MSNNFKDDFEKNRQSIDTNSHQDHTEDVEKDQSELEHQDTIENT
                     EQQFPPRNAQRRKRRRDLATNHNKQVHNESQTSEDNVQNEAGTIDDRQVESSHSTESQ
                     EPSHQDSTPQHEEEYYNKNAFAMDKSHPEPIEDNDKHETIKDAENNTEHSTVSDKSKA
                     EQSQQPKPYFATGANQANTSKDKHDDVTVKQDKDESKDHHSGKKGAAIGAGTAGVAGA
                     AGAMGVSKAKKHSNDAQNKSNSDKSNNSTEDKASQDKSKDHHNGKKGAAIGAGTAGLA
                     GGAASKSASAASKPHASNNASQNHDEHDNHDRDKERKKGGMAKVLLPLIAAVLIIGAL
                     AIFGGMALNNHNNGTKENKIANTNKNNADESKDKDTSKDASKDKSKSTDSDKSKEDQD
                     KATKDESDNDQNNANQANNQAQNNQNQQQANQNQQQQQQRQGGGQRHTVNGQENLYRI
                     AIQYYGSGSPENVEKIRRANGLSGNNIRNGQQIVIP"
BASE COUNT         1770 a          743 c          763 g         1323 t
ORIGIN      
        1 atttatttta ctatatagaa ggcttgcgaa tttcttgaaa agaatttaat caaattaaag
       61 caaaataata tacacataat aataaaaagc aggtgactat caataaacga tagcttgcct
      121 gctttttcta tagaacattt gtctaaaaaa tcaattattc aaattttaaa gcgtccccat
      181 caaatgattc gtctgcaatt ttaatagaat ctgtagggca tccatcaatt gcatcttcca
      241 tatcttcata taattcctca ggtacttctg cagtaccttg gttatcgtca aggattacga
      301 aagcaatacc ttcgtcgtcg taatcatata tatctggcgc tgctgcaccg catgcaccac
      361 atgcaataca agtatccata tcaacgattg tatattttgc caatgtcttc gcctcctttg
      421 ataaaaatgc taaaatagta atgtgactaa aattttagac agcatcattt ttattttcaa
      481 attatccgtt ttacagagtg agggttaaat ttgcaacaca ttataaaaac agcattacaa
      541 caaacattta actataaaac aaataaaagt atttacaata tcttagttgg taagaaatct
      601 caccaaacct tttttgacgc ttgtagtcaa caacagttgt cattatatca cagtttacca
      661 ctattaaaat atccgtcttt tgagctattt ttagaaaaaa tcaatgaatt taatgctgaa
      721 atggaaatca tgttgcatcc tagatataca tttgaaagca tggggcaaac atttcaagca
      781 attcaactat tagtgcaaac catgtctaat accaaacaac atgtttttca ttttgtacca
      841 atctctcaaa ataataagat acaagaaact gtaaagattg tctataacta cattaaagaa
      901 aaccaattac aaattgactt tgaaaatgaa ctacataact tgtttaaagc aataacttta
      961 aaagggccat gttacttaca ttattatttg caaggctatg atgaaccaat gtatacgaga
     1021 cagcaagtta gtttaataga aaaactatct caacagcaat tgtttgaata cgaaatgaat
     1081 aatttagtga caatgatgtt tgaattagaa agtggagaat atactatttt atcaaaaata
     1141 ataatgaaac ctacattatt aaatcaaact tatattactt atacaaaatt gcttgaacaa
     1201 ttcacgatgg aagatatagc ggctcaacaa caagttaaaa tcaatactat cgaagatcat
     1261 gtacttgaaa tcttaatcaa aggttacatg tctaattacg atgattatgt tgaactagaa
     1321 gatcaactcc agtttttgaa tttttatcaa caacatcgtg gcgaacgatt aaaattttac
     1381 aaagaacaat ttgacacgtt atcatatttt caattaaaag tattaatcgt tggatttgaa
     1441 agaggtgatc tgaatgttgc atgatatttt acgaaacaaa tttggcttcg agaattttaa
     1501 accgggacaa caggaaatta tagaaagtat aatgtctcaa caacacactc taggtattct
     1561 tccaactgga agtggaaaga gtttgtgtta tcaaatacct acgtatttat caggtaagcc
     1621 gacattaatt atctcaccgt taatatcttt aatggatgac caagttatgc agttgaaaat
     1681 aaatggagaa aaacgtgtaa catgtattca ctctggtatg gatgaaattg agaaaaagca
     1741 taatattaaa tgtttactac atagccgctt catctttcta agtccagaat ttctcctgca
     1801 accgtcaaat tttaaattaa tatctatgat agactttggc atgattgttc tagatgaagc
     1861 acattgccta tctgaatggg gatatgattt cagaccacat tatgctctaa taggaaaagt
     1921 aacaaagcat tttaaagaag cggttgtctt agcgttgaca gcaactgcac caccgcattt
     1981 acaagatgat ttgacggaaa tgttagcgat tcaattcaac gttattaaaa ctacaatgaa
     2041 tcgcccaaac ataagcttta agcatcttaa ttttcatgat gatgaagata aaattgagtg
     2101 gttgctgccg tttctacaac agtcgggacc aacgattatc tatgtctcat cgaaaaagat
     2161 gtgtctgaat ttagcgcaac ttatttatga ttcaggtttt cttactggca tttatcatgg
     2221 tgatatgaat tatcaagagc gacacacagt tcaacaacaa tttttaaata atgatattcc
     2281 gattatagtc gcaacgagtg cttttggtat gggtattaat aaaaaagata ttcgcacaat
     2341 cattcacttt catctttcaa caagtccttc taactacatt caagaaattg gccgtgcagg
     2401 tcgcgatggt gaactaagtc aggcaattag tttatttcaa ccggacgata aatatatttt
     2461 agaaacgtta ttatttgcag atatgataac agaagaagat gtacaaaatt tcgaaatagg
     2521 agaattttta gcacccgata aacaagacgt tttgacaacg ttgcattcat tctatagtat
     2581 cggcgccttg aaacagatat ttaagcaatc atttaaacga aagcaattag gattctttcg
     2641 catgattggc tattgcaaat tggatcaatg tagacggaag tatttattag aatttttcgg
     2701 tgaatatcca ccggcacaag atcgatgttg tgacaatgat tctaatataa ctgatatcgt
     2761 aattttaaat aagaagaagg taattagaag tattggattt gatgaaaagt tgcaaaattt
     2821 atttctcaga tagtattact ttactaaaag aaaattgaca agctataatt agtgtataca
     2881 caattgaaaa atgattgaaa taattttgaa aaatatacat aaacatatgt catgtgggta
     2941 tattttatgt aaaatcattg taatagaata gaaaggaaga tggctatgtc taataatttt
     3001 aaagatgact ttgaaaaaaa tcgtcaatcg atagacacaa attcacatca agaccatacg
     3061 gaagatgttg aaaaagacca atcagaatta gaacatcagg atacaataga gaatacggag
     3121 caacagtttc cgccaagaaa tgcccaaaga agaaaaagac gccgtgattt agcaacgaat
     3181 cataataaac aagttcacaa tgaatcacaa acatctgaag acaatgttca aaatgaggct
     3241 ggcacaatag atgatcgtca agtcgaatca tcacacagta ctgaaagtca agaacctagc
     3301 catcaagaca gtacacctca acatgaagag gaatattata ataagaatgc ttttgcaatg
     3361 gataaatcac atccagaacc aatcgaagac aatgataaac acgagactat taaagatgca
     3421 gaaaataaca ctgagcattc aacagtttct gataagagta aagctgaaca atctcagcaa
     3481 cctaaaccat attttgcaac aggtgctaac caagcaaata catcaaaaga taaacatgat
     3541 gatgtaactg ttaagcaaga caaagatgaa tctaaagatc atcatagtgg taaaaaaggc
     3601 gcagcaattg gtgctggaac agcgggtgtt gcaggtgcag ctggtgcaat gggtgtttct
     3661 aaagctaaga aacattcaaa tgacgctcaa aacaaaagta attctgacaa gtcgaataac
     3721 tcgactgagg ataaagcgtc tcaagataag tctaaagatc atcataatgg caaaaaaggt
     3781 gcagcgatcg gtgctggaac agcaggtttg gctggaggcg cagcaagtaa aagtgcttct
     3841 gccgcttcaa aaccacatgc ctctaataat gcaagccaaa accatgatga acatgacaat
     3901 catgacagag ataaagaacg taaaaaaggt ggcatggcca aagtattgtt accattaatt
     3961 gcagctgtac taattatcgg tgcattagcg atatttggag gcatggcatt aaacaatcat
     4021 aataatggta caaaagaaaa taaaatcgcg aatacaaata aaaataatgc tgatgaaagt
     4081 aaagacaaag acacatctaa agacgcttct aaagataaat caaaatctac agacagtgat
     4141 aaatcaaaag aggatcaaga caaagcgact aaagatgaat ctgataatga tcaaaacaac
     4201 gctaatcaag cgaacaatca agcacaaaat aatcaaaatc aacaacaagc taatcaaaat
     4261 caacaacagc aacaacaacg tcaaggtggt ggccaaagac atacagtgaa tggtcaagaa
     4321 aacttatacc gtatcgcaat tcaatactac ggttcaggtt caccggaaaa tgttgaaaaa
     4381 attagacgtg ccaatggttt aagtggtaac aatattagaa acggtcaaca aatcgttatt
     4441 ccataatata actatataaa ttgtaactga actgctatat acaaacgtgc atattataag
     4501 tatctctaaa tattttggag aacttaaatt gcgcttataa gtatgtagcg gttttttcat
     4561 ttttcaaagt ttgttattta acaaggtctt gtctcgaat
//
LOCUS       DAPDIM010000120         4206 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000120 DAPDIM010000000
VERSION     DAPDIM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4206
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.126"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..793
                     /locus_tag="RFE25_002728"
     CDS             <1..793
                     /locus_tag="RFE25_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDU2817741.1"
                     /translation="ALQHIQKHKIGKMELSKINRQVYQKFINDYSKEHAKETIRKTNG
                     AIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSEQEKFISVTEYEILKDHVRKKRTRS
                     SLALFIMICTGCRVSGARNIKIEHINQVKNTIFIDERKTDTSPRYISIAKSDMKHIMD
                     VISTFAISYDGYIFKEAGSIINLHAINNALKSACRVNNIPIITSHALRHTHCSYLLAK
                     GVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEEDKKTTKILESM"
     gene            844..1674
                     /gene="sph"
                     /locus_tag="RFE25_002729"
                     /pseudo
     CDS             844..1674
                     /gene="sph"
                     /locus_tag="RFE25_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239616.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sphingomyelin phosphodiesterase"
     gene            complement(1912..2928)
                     /gene="lukG"
                     /locus_tag="RFE25_002730"
     CDS             complement(1912..2928)
                     /gene="lukG"
                     /locus_tag="RFE25_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component leukocidin LukGH subunit G"
                     /protein_id="HDU2817742.1"
                     /translation="MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLD
                     GDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGY
                     WNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGG
                     LTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTND
                     SDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQF
                     VVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLND
                     NEKK"
     gene            complement(2950..4005)
                     /gene="lukH"
                     /locus_tag="RFE25_002731"
     CDS             complement(2950..4005)
                     /gene="lukH"
                     /locus_tag="RFE25_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component leukocidin LukGH subunit H"
                     /protein_id="HDU2817743.1"
                     /translation="MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVD
                     KSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYD
                     KNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNK
                     ISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHW
                     SVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLT
                     YLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKT
                     VKVVDKYSDDNKPYKEG"
BASE COUNT         1419 a          683 c          599 g         1505 t
ORIGIN      
        1 tgcattacaa catatacaaa aacataaaat aggtaaaatg gagttatcaa agataaatag
       61 acaagtttat cagaaattca taaacgatta ttcaaaagaa cacgcaaaag aaactataag
      121 aaaaacaaac ggtgctattc ggtcagcttt agatgacgca ttatatgatg ggcttatttt
      181 taaaaatccc gcttataaag ttaattataa agccggaaaa cctacgaagt cagaacaaga
      241 aaaattcatc tcggtaactg aatatgaaat actaaaagat cacgtcagaa agaagagaac
      301 tcgttcatca ttagcgctat tcataatgat ttgtacgggt tgtcgtgtca gtggtgcaag
      361 aaatataaag attgagcata tcaaccaagt gaaaaacact atatttattg acgagcgaaa
      421 aaccgatact tcccctagat atatcagtat cgctaaatct gatatgaaac acattatgga
      481 cgtcataagt acatttgcaa ttagctatga tggttacatt ttcaaagaag ccggatctat
      541 aattaacctt catgctatca ataatgcttt gaaatcagcc tgtagagtca ataatatacc
      601 aattattaca tcgcacgcat taagacacac tcattgttct tatttactag caaaaggtgt
      661 atctatacat tacatttcta aaagattagg tcataaaaat atagcaataa ctacatccgt
      721 gtattctcat ttgttagaag aaaaatttaa tgaagaggac aaaaaaacaa ctaaaatttt
      781 agaaagtatg taatttaggg acccattagg gactccaaac ccaataaata ctgttgttac
      841 aaggtttcta tgtatccaaa ctggggacaa tataaacgcg ctgatttaat cggacaatct
      901 tcttatatta aaaataatga tgtcgtaata ttcaatgaag catttgataa tggtgcatca
      961 gacaaattat taagtaatgt gaaaaaagaa tatccttacc aaacacctgt actcggtcgt
     1021 tctcaatcag gttgggacaa aactgaaggt agctactcat caactgttgc tgaagatggt
     1081 ggcgtagcga ttgtaagtaa atatcctatt aaagaaaaaa tccagcatgt tttcaaaagc
     1141 ggttgtggat tcgataatga tagcaacaaa ggctttgttt atacaaaaat agagaaaaat
     1201 ggtaagaacg ttcacgttat cggtacacat acacaatctg aagattcacg ttgtggtgct
     1261 gaacatgatc gaaaaattag agctgaacaa atgaaagaaa tcagtgactt tgttaaaaag
     1321 aaaaatatcc ctaaagatga aacggtatat ataggtggcg accttaatgt taataaaggc
     1381 actccagagt tcaaagatat gcttaaaaac ttgaatgtaa atgatgttct atatgcaggt
     1441 cataatagca catgggaccc tcaatcaaat tcaattgcga aatataatta ccctaatggt
     1501 aaaccagaac atttagacta tatatttaca gataaagatc ataaacaacc aaaacaatta
     1561 gtcaatgaag ttgtgactga aaaacctaag ccatgggatg tatatgcgtt cccatattac
     1621 tacgtttaca atgatttttc agatcattac ccaatcaaag cctatagtaa atagtgctca
     1681 actaactaat aactcgcttc gttctaaaag gacgaagcga gttatattgt taaaatttga
     1741 attgacttac attttaataa aatcatctta acaactttaa tttttcatta atacaagtct
     1801 ttactctaca ctcaaacaag attcatacac tgcacatcat aataaatcta tctactcaaa
     1861 tataaataaa agttacctac tacattctat gtagcaggca acttttatta cttatttctt
     1921 ttcattatca ttaagtactt ttacaaactt cacatcatgt gtcttccaat caacttcata
     1981 taatgctgat aatttttctt cttttttatc tacatggttt tcaccagacc aatagcccca
     2041 gaaaccatgg cgattccaat ctattttaaa ctcatccatt gatcttttat aatgaacaac
     2101 aaattgtgat ttacctttgt cttttttatc atgtgacata acagctaaaa attctggatt
     2161 aaacccttca gacacagtta caggcatttt gtctttaggt gtgaaattat ctttcgccca
     2221 taaatttcca tttcgtgtta aagaaaagat ttcactttta gttctattat cactatcatt
     2281 agttaattgt ctcgtatggt catgtcccat attatttatc aaatgtgctt ctactttcca
     2341 acctacacct ttatgtgacg tagattgatc aagtaatgta cgatatgatg gttgttgata
     2401 actaatcgtc tctgaataat tactctcttt tgtaatattt cctgttaagc ctccacgatt
     2461 aatcgaaaaa tctccacctg ttttataacc atacgtatat ttaacttctc ttgattcatc
     2521 ctgatttttt ggtgcaaagt cagtcacatt tgtattgttg ttgtcatcaa cattttgaat
     2581 tgaaactgaa taagatccag gccatcttaa tgtactattc caataaccat ttgggtctaa
     2641 aattctcaaa ccactaccaa ttgtaccttt tgctttaata aatactgttt ctttatcata
     2701 attaggttca gttaagaaat taaattgtaa gctttgagta atattttttt gactatcact
     2761 tgttgtagct gtacgtgtat acattttagt atcaccatca agattcttct cagaaacagc
     2821 tttaatttca gaattaattt ttgcataaga agttgccgga aatacagtta atgcagtaga
     2881 tattgctaaa ctacaaattg tgatgttttt gtataattgt ttaatcatta gtaatccgcc
     2941 ctttcaatat tatccttctt tataaggttt attgtcatca gaatatttat caacgacttt
     3001 aactgtttta tttttccaat caacttcata agtgacaatt aacctttgac catctttatt
     3061 tttttctaaa attggaggtg cataatgtat tccaggtctg tttttcaaaa tatcttgatt
     3121 tcgtgtgtat gttacttcaa attgcgtttt ctcatttgac ttttcattag ataaataagt
     3181 taaaaattct ggattaaagc cacttcttac taatgctggg tatctatatt ttgaagcaaa
     3241 gcttagttca gggttttcta cagtagcaat tctcgtattt ctatagaata ataattcatc
     3301 atttctattt ttcacttctc caccatactt caagtcattc gcaataactg accagtgtac
     3361 atgccagtta ttatttttac cgctggcaat tgtgtcataa ttttgctgat tataactaat
     3421 cgttttggag tagctatttg atgaagttcg tccaatacct ttcgttgaat cgaatttacc
     3481 acctgagcta tatgaaaatg tactgtctac tttcgcagtt gaaattttat ttttcggcaa
     3541 ttggtctaat atttcagttt tacgatttct ttttacttga aaatctacat ggtactcact
     3601 tggatacttt aaccaatttg aatttttttc ttctttatga gattcaaact ttaaatttga
     3661 atgaattgag ccttgttttt taacaagtaa tacattcttg tcataagttg gatcatcgat
     3721 aaagtcgaat tgtaaatttt ggagtatatt tgttttctca tcatatactg tttcagttcg
     3781 ttttgtgatt ttaccgtttt tcccaatatc atcaggtact gttgaatttt tatctttatt
     3841 agtaacatta cgtttgtctt tttgttgaga cttatcaaca tgttctttct tattttgatc
     3901 ttgcgagtct ttatgagctg aatttgcttg agtcgttgct gctgataaca ataaaattgc
     3961 acatgataat gatgacgcta ttaaaacacg ttttttattt ttcattgtta taaccttctt
     4021 tcgtatgatt gatatttgtt gatatgtatc gacatgtgaa taatatcaca aaaatagaga
     4081 atatatattt aactatttat taaatgattt tgttaatatt attaaatact ttatcctctt
     4141 taaaaataat gtgtgtacaa agtcattaat ttagcaaata tttttattta gtagttaata
     4201 accatc
//
LOCUS       DAPDIM010000121         4043 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000121 DAPDIM010000000
VERSION     DAPDIM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4043
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.127"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..727
                     /locus_tag="RFE25_002732"
     CDS             <1..727
                     /locus_tag="RFE25_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1672 domain-containing protein"
                     /protein_id="HDU2817744.1"
                     /translation="AIEFAKKHRKEFEKVGEQFFKDNFGLKVKATNVVGKDDGVEVYV
                     HCEDHGIVFNASLPLYKDAIHQKGSMRSNDNGDDMSMMVGTVLSGFEYRAQKEKYDNL
                     YKFFKENEKKYQYTGFTKEAINKTQNVGYQNEYFYITYLSRNLKEYRKYYEPLIHKND
                     KEFKEGMQRARKELDYTANSNTVATLFSTNDKKNRKEKINNVIDLSEKIERTKDMPIK
                     NTITTQLGNKLIGTKKLVLMIRK"
     gene            749..2911
                     /locus_tag="RFE25_002733"
     CDS             749..2911
                     /locus_tag="RFE25_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817745.1"
                     /translation="MNKINDRDLTELSSYWVYQDINKDNDFTVNGKRFKQVDEYNDNG
                     NKNKKGASDLKIYELLDEKGKPTGEQTMIYQGTSNEAINPNNPLKSLDIGDDWLQNAK
                     LMDNSNKSTDYLKQSDEFADLYRDKLNDANKLSKYNFTQKYGVSPNNYKNKTIVADGG
                     NSEGGAGAKYQGAKHPNEKVVATDPAMVPYAAWQKFARPRFDNMISFNSTNDLLTWLQ
                     DPFIKDMPGKRVNISDGVPRLDALIDSHVGYKRKLNRKDNTYDTVPLIKIKSVKDTEI
                     KNGKKVKKTINITLDMDGRIPINVWTGDSIARSGRGTLIKLNLENLDALSKLITGETS
                     GMLAECVIFLNESFNISENENKNFADRKQQLSEGFKDKINLFQLEEMERTLISKINSL
                     EEVADETIESISAVKHLLPDFALDALKERINELFKGIKSFIEKVYDSIDNEILEIFKN
                     IDHDFRDGVSEEMMKHLKVVKQNIERIKNQNDIYGRQIAEIRSIMKQQDATILDGNFQ
                     INCSGENMVQGLVIPSNYLGRKMKILKDHIDDGIKKIADYVQSIYDEYASKIVDVIKY
                     LINTIPKIRKNLRHAIEMLNVKKKEFLSLIPNVTCNYIKTKLEELDNTLGKWEPFLND
                     LKAVSPILDNHLDDIVKNMKPLIVQMLFEPSHYDDMFILNTQAHARLDQMAQQFEVVC
                     NGLNENEGQAIQTMDQSASLIRSNLIQVKEQLEKLAVY"
     gene            3001..3906
                     /locus_tag="RFE25_002734"
     CDS             3001..3906
                     /locus_tag="RFE25_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020807974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1672 domain-containing protein"
                     /protein_id="HDU2817746.1"
                     /translation="MFKRTKLILIATILLSGCSTTNNESNNETKSVPEEMEASKYVGQ
                     GFQPPAEKDAIEFSKKHKDKIAKRGEQFFMDNFGLKVKATNVVGSGDGVEVFVHCDDH
                     DIVFNASIPFDKSIIESDSSLRSEDKGDDMSTLVGTVLSGFEYRAQKEKYDNLYKFLK
                     ENEKKYQYTGFTKEAINKTQNSGYENEYFYIVANIPTLQEYRKYYEPLIKKNNLNFKK
                     GMKQARKGVGYKAAIEVHTTLFSRSSNFSKDKKLDDVLDLSESTKKLHLNFENTKIFL
                     QLAKSTISTNRVNYSDNESIRIEVE"
BASE COUNT         1681 a          482 c          734 g         1146 t
ORIGIN      
        1 tgcgattgaa tttgcgaaga agcatcgtaa agaatttgaa aaagtaggtg aacaattctt
       61 taaagataac tttggactaa aagttaaagc tacaaatgtt gtaggtaaag atgatggtgt
      121 agaagtttat gtgcattgcg aagatcatgg cattgtattt aatgcaagtc tacctttgta
      181 caaagatgcc atccatcaaa aaggatcaat gcgcagtaat gacaatggtg atgatatgag
      241 tatgatggtg ggtacagtgc tgagtggctt tgaatatcga gcgcaaaaag aaaagtatga
      301 taacttatat aaattcttca aagaaaatga aaagaaatat caatatacag gctttacaaa
      361 agaggcaatt aacaagacac aaaacgttgg atatcaaaat gaatactttt atatcacata
      421 tttatcaaga aacttaaaag aatatcgtaa atattacgaa ccgttgattc ataaaaatga
      481 taaagaattt aaagagggta tgcaacgagc tagaaaagag ttagattata ctgctaatag
      541 taatacagta gcaacgttgt ttagtacgaa tgataaaaaa aatagaaaag aaaagataaa
      601 taatgtaata gatttatccg agaaaattga aagaacaaaa gatatgccaa tcaagaatac
      661 tataactact caattaggaa ataaacttat tggcacaaaa aagctcgttt tgatgataag
      721 aaagtagtgt cgtttggagc atttgaagat gaataaaatt aatgatagag acttaacaga
      781 attgagtagt tactgggttt atcaagacat caataaagat aatgatttta cagttaacgg
      841 aaaaagattt aagcaggttg atgaatataa tgataatgga aataaaaata aaaaaggtgc
      901 ctcagattta aaaatttatg aattgttgga tgaaaaagga aaaccaactg gtgaacaaac
      961 catgatttat caaggaacat ctaatgaggc aataaaccct aataatccat taaaatcttt
     1021 agatatcgga gatgattggt tacaaaatgc gaaattaatg gataatagta ataagtcaac
     1081 ggattatctt aagcaatcag acgaatttgc agatttatat agagacaaac taaatgacgc
     1141 taataaatta agtaagtata actttacaca aaaatatggt gttagtccaa ataattacaa
     1201 aaacaaaacc attgtggcgg atggcggtaa ttcggaaggc ggtgcaggag caaaatatca
     1261 aggagcgaaa catccaaatg aaaaagttgt tgctactgac ccagcaatgg taccttatgc
     1321 tgcttggcag aaatttgcta gaccacgctt tgataatatg attagtttta atagtaccaa
     1381 cgatttatta acatggttac aagatccatt catcaaagat atgccaggaa aacgcgttaa
     1441 cattagtgat ggtgtgccca ggttagatgc tttaatagac agccatgtag gttataaaag
     1501 gaagttaaat agaaaagaca acacatacga tactgtacca ctaatcaaaa ttaagtcggt
     1561 aaaagataca gaaattaaaa atggaaaaaa agtaaaaaag actattaaca taacattaga
     1621 tatggatggg cgaattccga taaatgtttg gacaggggat tcgattgcac gttctggaag
     1681 aggaacttta attaaactta atttagaaaa tcttgatgcg ttgagtaaac tgattactgg
     1741 tgaaactagt ggtatgttag cagaatgcgt aatcttttta aatgaaagtt ttaacatctc
     1801 agaaaatgaa aataaaaatt ttgcagatag aaagcaacaa ttatcagaag gatttaagga
     1861 taagattaac ttatttcaat tagaagaaat ggaaagaact ttaattagta aaataaactc
     1921 acttgaagaa gttgcagatg aaacaataga aagtattagt gctgttaaac acttattacc
     1981 tgattttgca ttggatgcat taaaagaaag aattaatgag ttgtttaaag gtataaaatc
     2041 ttttatagaa aaagtgtatg atagtataga taatgaaatt ttagaaattt tcaaaaatat
     2101 agatcacgac ttcagagatg gagtatctga agaaatgatg aaacatttga aagtagtgaa
     2161 acagaatata gagcgaataa aaaatcaaaa tgatatttat ggtaggcaaa ttgcagaaat
     2221 tagaagtatt atgaaacaac aagatgcaac aattttagat gggaatttcc aaattaattg
     2281 tagcggcgaa aatatggtac agggtctagt tataccttct aattatttag gaagaaaaat
     2341 gaaaatatta aaagaccata tcgatgatgg tattaaaaaa atagcagact atgttcaaag
     2401 tatatatgat gaatatgcat cgaaaattgt tgatgtaata aaatatttga ttaatacaat
     2461 tcccaaaata cgtaagaatt taagacatgc aattgaaatg ttaaatgtaa aaaagaaaga
     2521 atttttgtcc ctgattccta atgtaacttg taattatatt aaaactaaat tagaagaatt
     2581 agataatact ttaggcaaat gggagccatt tcttaatgat ttaaaagcag tgtcaccaat
     2641 tttagataac catttagatg atattgttaa gaacatgaag cctttgattg tacagatgtt
     2701 atttgaacca tcacattatg atgatatgtt tattttaaac acacaagctc atgcacgtct
     2761 tgatcaaatg gcacaacagt ttgaagttgt ttgtaatggc ttgaacgaaa atgaaggaca
     2821 agcaattcaa acgatggatc aatctgcctc tctaatacgg tcaaacttaa ttcaagttaa
     2881 agaacaatta gaaaaactag ctgtatacta agtaatttat taaatgctac ttgttttctt
     2941 tgagaataag tagttttttt aacataaaag ttttacaaac acataaatgg gtgatgagct
     3001 atgtttaaaa gaacaaaact aatcttaata gcaacgatac tactatcagg atgttcaact
     3061 accaataacg aatccaacaa tgaaacaaaa tcagtgccag aagaaatgga agcttcaaaa
     3121 tatgtaggac aaggcttcca accacctgca gaaaaagatg cgattgaatt ttcgaagaag
     3181 cataaagata aaattgctaa acgtggcgaa caatttttta tggataactt tggactaaaa
     3241 gttaaagcta caaatgttgt aggtagtggc gacggtgtag aagtattcgt gcattgtgat
     3301 gaccacgaca tcgtatttaa tgcaagtatt ccatttgaca aatcaataat tgagagtgat
     3361 agctcattaa gaagtgagga taaaggcgat gatatgagta ctttagttgg tacagtgttg
     3421 agtggctttg aatatcgagc gcaaaaagaa aagtatgata atttatataa atttttaaaa
     3481 gaaaatgaaa agaaatacca atatacagga tttactaaag aggcaattaa caaaacacaa
     3541 aatagtggat atgaaaatga atatttttat atagttgcta atataccgac gctccaagaa
     3601 tataggaaat attacgaacc cctaataaag aaaaataatc tgaattttaa aaaaggtatg
     3661 aaacaagcaa ggaaaggagt aggctataaa gctgcaatag aagtacatac aacattgttt
     3721 tcgagaagta gtaacttttc aaaggacaaa aaattagatg atgttttaga tttgtctgaa
     3781 agtacgaaaa agttacacct taattttgaa aatacgaaaa tatttttaca actagcaaaa
     3841 tctactatta gcactaatcg agttaattac agtgataatg agtctataag gattgaggtc
     3901 gaatgacttg aaatcagcta atttctctat attctaaaca aacacataaa tgggagatgg
     3961 gctatgttta aaagaattaa actaatctta atagcaacga taatactatc aggatgttca
     4021 actaccaata acgaatccaa caa
//
LOCUS       DAPDIM010000122         3772 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000122 DAPDIM010000000
VERSION     DAPDIM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3772
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.128"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            151..657
                     /locus_tag="RFE25_002735"
     CDS             151..657
                     /locus_tag="RFE25_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817747.1"
                     /translation="MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYI
                     SLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVV
                     LEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIF
                     NYRMRSYK"
     gene            917..1414
                     /gene="efb"
                     /locus_tag="RFE25_002736"
     CDS             917..1414
                     /gene="efb"
                     /locus_tag="RFE25_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement convertase inhibitor Efb"
                     /protein_id="HDU2817748.1"
                     /translation="MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSIN
                     HNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTD
                     ATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLK
                     QGLVR"
     gene            1564..1914
                     /gene="scb"
                     /locus_tag="RFE25_002737"
     CDS             1564..1914
                     /gene="scb"
                     /locus_tag="RFE25_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement inhibitor SCIN-B"
                     /protein_id="HDU2817749.1"
                     /translation="MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFH
                     DKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVA
                     LEKIYKEIDEIINR"
     gene            2276..2473
                     /locus_tag="RFE25_002738"
     CDS             2276..2473
                     /locus_tag="RFE25_002738"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817750.1"
                     /translation="MQVGVGPQQREIGSPIPTDNASWRGPNIEKLDHQFQQTMQVGVG
                     PNTEAGEKSAYKNVQVGGAPT"
     gene            complement(2680..2865)
                     /locus_tag="RFE25_002739"
     CDS             complement(2680..2865)
                     /locus_tag="RFE25_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817751.1"
                     /translation="MNKHINKKATKLLEDYKKVQQRKSEETDRGCLKSVIMLIVLFFL
                     IIFGIVACSTNVNFFFQ"
     gene            complement(3487..3720)
                     /locus_tag="RFE25_002740"
     CDS             complement(3487..3720)
                     /locus_tag="RFE25_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817752.1"
                     /translation="MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGK
                     LKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH"
BASE COUNT         1414 a          497 c          567 g         1294 t
ORIGIN      
        1 cacttacatt tttaattaga taaaatagtg taaaatcacg tgccaagatt actatagagt
       61 aggcattgag tattattggc aatcacttaa gtgattgtta tttttcgtgg tcaataataa
      121 agatataaat aaatatattg aggtcaaacg atgataatta aaattttaac aattctatta
      181 ctactttgta tattgagcta tttggttaca aatagaaaga agccttttct gttcttaaag
      241 acactcttta tgggtgtggt atttatcttt ataggatata tttcactggc aatatctgcc
      301 gtaattattt atggtattat tcaatttatc acaattgatt ttggtagttt tttcttaatg
      361 ggtattatat tgatcttgat ttcaagtata ttccaattat ttatagttag attacttttt
      421 agaaaaaaga atgtcgattt gacagaggtt gtcgttttag agcatttaat tcaatggttc
      481 ttagtttact ttgcgatcta tcaagcagta aatgaaaaaa tggacattaa tgatattaat
      541 atcgacaatt tccaatctgt cttttttgac gtgtctaatt tgaatttagt aattctacca
      601 acgttaatca ttagctgggt cacaatattt aactatagaa tgagaagtta caaataaaat
      661 ctatgaaatt ataccatcag acaccaacat tcaaatggtg tctttttttg ttgtgtggtt
      721 ttatttttga aattcgaaaa agtagaggcg tgaatttttt gactagtgta taagtgctga
      781 tgagtcacaa gatagataac tatattttgt ctatattata aagtgtttat agttaattaa
      841 taattagtta atttcaaaag ttgtataaat aggataactt aataaatgta agataataat
      901 ttggaggata attaacatga aaaataaatt gatagcaaaa tctttattaa caatagcggc
      961 aattggtatt actacaacta caattgcgtc aacagcagat gcgagcgaag gatacggtcc
     1021 aagagaaaag aaaccagtga gtattaatca caatatcgta gagtacaatg atggtacttt
     1081 taaatatcaa tctagaccaa aatttaactc aacacctaaa tatattaaat tcaaacatga
     1141 ctataatatt ttagaattta acgatggtac attcgaatat ggtgcacgtc cacaatttaa
     1201 taaaccagca gcgaaaactg atgcaactat taaaaaagaa caaaaattga ttcaagctca
     1261 aaatcttgtg agagaatttg aaaaaacaca tactgtcagt gcacacagaa aagcacaaaa
     1321 ggcagtcaac ttagtttcgt ttgaatacaa agtgaagaaa atggtcttac aagagcgaat
     1381 tgataatgta ttaaaacaag gattagtgag ataatacttc tgtcattatt ttaagttcaa
     1441 aataatttaa tattatatta ttttttatta ataaaacgac tatgctattt aatgccaggt
     1501 taatgtaact ttcctaaaat tgactatata atcgttaagt atcaatttta aggagagttt
     1561 acaatgaaat ttaaaaaata tatattaaca ggaacattag cattactttt atcatcaact
     1621 gggatagcaa ctatagaagg gaataaagca gatgcaagta gtctggacaa atatttaact
     1681 gaaagtcagt ttcatgataa acgcatagca gaagaattaa gaactttact taacaaatcg
     1741 aatgtatatg cattagctgc aggaagctta aatccatatt ataaacgtac gattatgatg
     1801 aatgaatata gagctaaagc ggcacttaag aaaaatgatt tcgtatcaat ggctgatgct
     1861 aaagttgcat tagaaaaaat atacaaagaa attgatgaaa ttataaatag ataataaata
     1921 aaacaggttg agacaaaaaa tggtcttaac ctgttttcaa tttgcatatg tgataaattc
     1981 tatatcaaaa tgcttatgta taatgaatga catttaaaag taggggagac aaatataaat
     2041 acaatagttc ctaggattac tctcaaaata actatatcaa ttatttactt tgctcttcta
     2101 ttttttaaaa tatgtacatg tttaaataat caaaagtgta cattattaaa ttatcatttc
     2161 cagttctagt gctatattgg tagtagttga ctaaatgaaa ataagcttat aacaagtttt
     2221 ttcaatactc gtggggcccc aacacagaga atttcgaaaa gaaattctac aaacaatgca
     2281 agttggggtg gggccacaac agagagaaat aggatcacca attccaacag acaatgcaag
     2341 ttggcggggc cccaacatag agaaattgga tcaccaattt caacagacaa tgcaagttgg
     2401 ggtggggccc aacacagaag ctggcgaaaa gtcagcatac aaaaatgtgc aagttggcgg
     2461 ggccccaaca tagaagctgg cgaaaagtca gcatacaaaa atgtgcaagt tggggtagga
     2521 catcgataaa aaaatacttt ttctttagaa attagtattt cttatgcatg agttttactc
     2581 atgtattcat tttttaagta gacattagct acagctaatg ataaagaacc actacataat
     2641 aaatcattag tggttcttta tcatttctat ctcactcttt tactggaaga aaaagtttac
     2701 gtttgtagaa catgccacaa taccaaaaat aattaagaaa aataagacga taagcatgat
     2761 gacacttttc aaacaacctc tatcagtttc ttccgatttt ctttgttgaa cctttttata
     2821 atcttcaagt agttttgtcg cttttttatt tatatgttta ttcatgatgt tgactcctta
     2881 taatatatgt ttaattcatt aaaatagttg aaaacatgac ttgaaataaa gatataaagc
     2941 taaagtaagg atgttcaatt gtttcaaatt ttatgaaagt ataacgttaa atatgttaat
     3001 ttgatgatga tatttgcttt ttattttcca aatggaattt acttaaactg atgcattaaa
     3061 atattaatga agcactagaa tacataaatg aatagtaatg gtgcacagta tagaataatt
     3121 aaggctatat taagtataaa tatcgttaac tgtaagctat ctttagtttt aatataaact
     3181 attaggataa tcgacgtaag aagaatcata tatattaatg atgaagaagt ccatacaaaa
     3241 tccgcatcat ttgttgttaa taatgggact ataattaatc cgaaattaat catgcatgct
     3301 atatatacta taatgttata cacaatgtta atttttgttc accaccttat acttctattt
     3361 taaaaacttc tttataatga tatattgttt aatgttgaaa taattagatt atctaatttt
     3421 catttgcttt acatgtaaaa ggctatatat agtatgctct ttatgattct aaatgctttt
     3481 taatatttaa tgctcatcaa catttggatt ttgaatattc aattcaaaaa ctttattagc
     3541 tacgtcaatt gtaaaatcag aaccatagtt gacatgagct acttttaatt ttccatctaa
     3601 ataatagatt gcgattgcaa catcgtaaaa ttcgtcaatg acaaataaac tcttttcgtt
     3661 tgttacaacc tcatgctctc ctgagtatac aacgttaatt tcccaatcat taaaaaccat
     3721 ttgttaacct ccttgaacat ttaaattgat tcaacttaag tttaacttat tc
//
LOCUS       DAPDIM010000123         3756 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000123 DAPDIM010000000
VERSION     DAPDIM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3756
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.129"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            41..238
                     /locus_tag="RFE25_002741"
     CDS             41..238
                     /locus_tag="RFE25_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817753.1"
                     /translation="MEQIKLKTFTAETLELLEKNINAFLSSEEATNLKLVNITIKEIE
                     ERTFPNNEEEFNAILTLSVNK"
     gene            295..1776
                     /gene="cls"
                     /locus_tag="RFE25_002742"
     CDS             295..1776
                     /gene="cls"
                     /locus_tag="RFE25_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDU2817754.1"
                     /translation="MRYTFSNDLGTLFTIILAIGFIINLVLAFIIIFLERNRRTASST
                     WAWLFVLFVLPLIGFILYLFFGRTVSARKLNKNNGNVLTDFDGLLKQQIESFDKGNYG
                     TDNKQVQKHHDLVRMLLMDQDGFLTENNKVDHFIDGNDLYDQVLKDIKNAKEYIHLEY
                     YTFALDGLGKRILHALEEKLKQGLEVKILYDDVGSKNVKMANFDHFKSLGGEVEAFFA
                     SKLPLLNFRMNNRNHRKIIVIDGQLGYVGGFNIGDEYLGLGKLGYWRDTHLRIQGDAV
                     DALQLRFILDWNSQAHRPQFEYDVKYFPKKNGPLGNSPIQIAASGPASDWHQIEYGYT
                     KMIMSAKKSVYLQSPYFIPDNSYINAIKIAAKSGVDVHLMIPCKPDHPLVYWATFSNA
                     SDLLSSGVKIYTYENGFIHSKMCLIDDEIVSVGTANMDFRSFELNFEVNAFVYDENLA
                     KDLRVAYEHDITKSKQLTKESYANRPLSVKFKESLAKLVSPIL"
     gene            1951..2859
                     /locus_tag="RFE25_002743"
     CDS             1951..2859
                     /locus_tag="RFE25_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDU2817755.1"
                     /translation="MIKLIQISNINKSFNKRCVLKNISFDIEQGKCIALIGKNGAGKS
                     TLIDILIGNVNANSGEIFDKDKLLQSENRSIMFQKTMFPDQLKVIEIINLYQSFYENP
                     LPLEEIIELTKFDSSQLNQFVNKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEI
                     REYFWSIIENLKEDNRTILYTSHYIEEVERMSDKIILIENGEIILNDSTSHIRTNQQS
                     QITLSDEYIRKLKLDKDDLVIQKNHNGTIKIITSNVNDTILYLQQLHINLDDIEIQKV
                     SIVDSYFNNKKQRGSNYDTKLLENRI"
     gene            2828..3559
                     /locus_tag="RFE25_002744"
     CDS             2828..3559
                     /locus_tag="RFE25_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDU2817756.1"
                     /translation="MILSYLKIEFKVIMRKKTTLILSILFPVIFYILFTSILELPEDV
                     KPKFYKEYMYSMTVYSLLSFSLLTFPLDIINEKQNEWRQRLMVTPFTFTSYYISKVVK
                     TMLQFAIAILVIFMVGHFYKGVAMSAVQWLESGIFLWLGASLLITFGILFSLLNDIQK
                     TSALANIVTIGLAVLGGLWFPINTFPNWLQHVAHVLPSYHLRKLGVDIASNHHINLIS
                     FAIILLYVLGSIIAVYCISHFKRAE"
     gene            3563..>3756
                     /locus_tag="RFE25_002745"
     CDS             3563..>3756
                     /locus_tag="RFE25_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDU2817757.1"
                     /translation="MKFLKDTSIAEISSILYLIFPIAGIFFNEVYGPKWLYIISVIVF
                     SLSYLILVIVNNRLNTLMFY"
BASE COUNT         1366 a          460 c          609 g         1321 t
ORIGIN      
        1 agttctatga tttaggaaat agagaaaaga ggggatttaa atggaacaaa ttaaacttaa
       61 aacttttaca gctgagactt tagagttatt agaaaaaaac attaatgctt ttttaagttc
      121 tgaagaagct acaaatttaa aattagtaaa tattactatt aaagaaatag aagaaagaac
      181 attcccaaat aatgaagaag aattcaatgc aattttaact ttatctgtga ataaataata
      241 tgatgtgaaa ggtgcaaaat gttttttgtg cctttcttta taggagaaaa gactatgcga
      301 tatacatttt caaatgattt aggaacactt tttaccatta ttttagccat tggattcatc
      361 attaatttag tattggcttt tattattatc tttttagaaa gaaatagacg tacagcgagt
      421 tcaacttggg catggctatt tgtacttttt gtcttaccat tgattggttt tattctttac
      481 ttgttttttg gtagaaccgt ttcggcacgt aaattgaata aaaacaatgg taacgtgtta
      541 acggatttcg atggactttt aaaacaacaa atagaaagct ttgataaagg taattatggt
      601 actgataaca aacaagttca aaaacatcat gatttagtac gtatgctttt gatggatcaa
      661 gatggttttt taactgaaaa taataaagtt gatcatttca ttgatggaaa tgatttatat
      721 gatcaagttt taaaagatat taaaaatgca aaagaatata tccatttaga gtactatact
      781 ttcgctttag atggtttagg taaaagaatt ttacatgctt tagaagaaaa attgaaacaa
      841 ggtctagaag taaaaatatt atatgatgat gttggatcta aaaatgttaa gatggcaaat
      901 tttgatcact ttaaatcatt aggtggcgaa gttgaagcat tttttgcttc taaattaccc
      961 ttattaaatt tccgtatgaa taacagaaat catagaaaaa tcatcgtaat cgatggtcaa
     1021 ctaggttatg tcggaggatt taacattggt gatgaatatc taggattagg taaactaggg
     1081 tattggagag atacgcattt acgtatacaa ggggatgcgg ttgatgcact gcagttgcga
     1141 tttattttag actggaattc gcaagcgcac cgtccacagt ttgaatatga tgttaagtat
     1201 ttccctaaaa agaacggacc attgggcaat tcaccaattc aaatagctgc aagtggccca
     1261 gctagtgact ggcatcaaat tgaatatggt tatacaaaaa tgattatgag cgctaagaag
     1321 tcggtatatt tgcaatcgcc ttatttcatt ccggataact catatataaa tgccattaaa
     1381 attgcagcta aatcaggtgt agatgttcat ctaatgattc catgtaagcc agatcatcct
     1441 ttagtttatt gggcgacatt ttcaaatgcc tctgacttat tatcaagtgg tgttaaaatt
     1501 tatacgtatg aaaatggatt tatacattct aaaatgtgct taattgatga tgaaatcgta
     1561 tcagtgggca cagcaaatat ggactttaga agttttgaat taaattttga agtaaatgcc
     1621 tttgtatatg atgaaaatct tgctaaggat ttaagggtgg cttatgaaca tgatattaca
     1681 aaatcaaaac aactaaccaa agaatcatat gccaatagac cgctgtctgt taaattcaaa
     1741 gaatcgttag caaaattagt ttcgccaatt ttataattta tttgtaagga gtctcgatta
     1801 tagaggctct ttttattttg cccaaaatta aaataacgat aaatatatta tgtaaaccta
     1861 ataatgacat ttgtcatttc aaatctatga caaagtgttc tattttaaat ctaataaatt
     1921 tactaatatt aaattaagaa aaaaatagag gtgattaaat tgattcaaat atctaatatc
     1981 aacaagtcat ttaataaaag atgtgttcta aaaaatattt cgttcgatat tgaacaaggt
     2041 aaatgtatcg ctttaattgg aaaaaatggt gctggaaagt caacgttaat tgatatatta
     2101 attggtaatg ttaatgctaa ttctggtgag atatttgata aagacaagtt attacaaagt
     2161 gaaaatcgca gtataatgtt ccaaaaaacg atgtttccag atcaattaaa agttattgag
     2221 attatcaact tatatcaatc attttacgaa aatccattac cattggaaga aataatagaa
     2281 ctgacgaaat ttgattctag tcaactgaac caatttgtaa ataaactttc tggtggtcaa
     2341 caacgattac tcgattttgt attatcttta atcggacaac cacaattgat cttattagat
     2401 gaaccaacat cgactatgga tatagaaatt agagaatatt tttggtcaat tattgaaaat
     2461 ttaaaagaag ataatcgaac gatactctat acatcgcact atattgaaga agtcgaacgt
     2521 atgtcagaca aaattattct cattgaaaat ggagaaataa tacttaatga ttcaacgtca
     2581 catattagaa ccaatcagca atctcagatt acgttatccg atgaatatat aagaaagtta
     2641 aaactagata aagatgattt agttattcaa aaaaatcata atggcactat caaaattatt
     2701 acttcaaatg taaatgatac gattttatat cttcaacaac ttcatattaa tttggatgat
     2761 attgaaatac aaaaagtctc aattgttgat tcatacttca acaataaaaa gcaaagggga
     2821 tctaattatg atactaagtt acttgaaaat cgaatttaaa gttataatgc gtaaaaaaac
     2881 aacattaata ttatctattt tatttcctgt gatattctat atattattta cttcgatatt
     2941 ggaattgccg gaagatgtta aacctaaatt ttataaagag tatatgtata gtatgacggt
     3001 ttatagtttg ttaagtttta gtttactaac ttttccatta gatattatta atgaaaaaca
     3061 aaatgaatgg cgccaaagat taatggtaac accatttact tttactagtt attatatttc
     3121 aaaagtagtg aaaactatgc tgcaatttgc aatagcgata ttagttattt ttatggttgg
     3181 acatttttat aaaggtgttg caatgagtgc agttcaatgg ttagagtcag gaatattttt
     3241 atggttaggt gcgtctctat taataacttt tggcatatta ttttctttgt taaatgatat
     3301 tcaaaaaaca agtgctttag ctaatatcgt aacaattggt ttagcagtat taggtggatt
     3361 gtggtttccg ataaacacat ttccaaattg gcttcaacat gttgctcatg ttttaccgag
     3421 ctatcatttg cgtaaactag gtgtagatat tgcttcaaat catcatatca atttaatatc
     3481 atttgctata atactcttgt atgttttagg gagtataata gcagtatatt gtattagtca
     3541 ttttaaaagg gcggaataaa atatgaaatt tttaaaagat acttcaattg ctgaaatatc
     3601 gtctatactt tatctgattt ttcctattgc cggtatattt tttaatgaag tatatggtcc
     3661 caaatggttg tatattatat cagtcattgt cttttcgttg tcgtatctta tattagttat
     3721 agtaaataat agacttaata cattaatgtt ttacat
//
LOCUS       DAPDIM010000124         3318 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000124 DAPDIM010000000
VERSION     DAPDIM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3318
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.130"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            112..345
                     /locus_tag="RFE25_002746"
     CDS             112..345
                     /locus_tag="RFE25_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HDU2817758.1"
                     /translation="MDYIGQYAVIHLVLHVVCICIAYWALQSIRLDQFFKKGYATQLQ
                     VCMIFVAILLGTAVSNFIVDLLQYSTQVKYLIK"
     gene            456..1721
                     /gene="murA"
                     /locus_tag="RFE25_002747"
     CDS             456..1721
                     /gene="murA"
                     /locus_tag="RFE25_002747"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDU2817759.1"
                     /translation="MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVN
                     VPALSDVETINNVLTTLNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMG
                     PLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI
                     HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTIT
                     INGVESLHGVEHAIIPDRIEAGTLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVE
                     LDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTANGHKVVTETVFENR
                     FMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSV
                     TELTHLDRGYVDLHGKLKQLGADIERIND"
     gene            1755..2195
                     /gene="fabZ"
                     /locus_tag="RFE25_002748"
     CDS             1755..2195
                     /gene="fabZ"
                     /locus_tag="RFE25_002748"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDU2817760.1"
                     /translation="METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGN
                     EPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVP
                     GDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK"
     gene            complement(2254..2694)
                     /locus_tag="RFE25_002749"
     CDS             complement(2254..2694)
                     /locus_tag="RFE25_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwpF-like family protein"
                     /protein_id="HDU2817761.1"
                     /translation="MKTFKAVRFQIVNEHGRIIEYELEDGVIINKEESGTGWLLEIVI
                     SNEHYETFKEYQDNEQLLDIRVVITRPANDPALFESTVKSIKNFKTTMSIVFECHIYT
                     LRQQYAESLLEQLIDDGLSGEELKKSFNRMMQSKPKLKDEKLEE"
     gene            2888..3283
                     /locus_tag="RFE25_002750"
     CDS             2888..3283
                     /locus_tag="RFE25_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDU2817762.1"
                     /translation="MLNKIVIVGRLTKDAQIFEKEDRKIATFCVATHRNYKDENGEIV
                     CDYLFCKAFGKLASNIEKYTNQGTLVGITGQMRSRKYDKDGQTHFVTELYVETIKFMS
                     PKSQNNEILSDSILDIDSQNIDNHDLLEI"
BASE COUNT         1187 a          467 c          590 g         1074 t
ORIGIN      
        1 gaattatata gtaagttagc ttaaacttta ctaaaaacgg gtattaaact ttgtatcatt
       61 atttaaattt ttcatgtaca atgtaataca gtaatcttat gaggtgataa aatggattat
      121 atcggacaat atgcagttat ccatttagtg ttacatgttg tatgtatttg tattgcctat
      181 tgggctttac aatcaattag attagatcaa ttttttaaaa aaggatacgc cactcaatta
      241 caagtgtgta tgatatttgt tgctatttta ttaggcactg cagtaagcaa ttttattgta
      301 gatttgttac aatactcgac gcaggtaaaa tatttaataa aataagtcta actctatgat
      361 ttgtaatcaa aactagatat aattaaataa tgacttaaaa taattttaaa atagggaaat
      421 gtaaagtaat aggagttcta agtggaggat ttacgatgga taaaatagta atcaaaggtg
      481 gaaataaatt aacgggtgaa gttaaagtag aaggtgctaa aaatgcagta ttaccaatat
      541 tgacagcatc tttattagct tctgataaac cgagtaaatt agttaatgtt ccagctttaa
      601 gtgatgtaga aacaataaat aatgtattaa caactttaaa tgctgacgtt acatacaaaa
      661 aggacgaaaa tgctgttgtc gttgatgcaa caaagactct aaatgaagag gcaccatatg
      721 aatatgttag taaaatgcgt gcaagtattt tagttatggg acctctttta gcaagactag
      781 gacatgctat tgttgcattg cctggtggtt gtgcaattgg aagtagaccg attgagcaac
      841 acattaaagg ttttgaagct ttaggcgcag aaattcatct tgaaaatggt aatatttatg
      901 ctaatgctaa agatggatta aaaggtacat caattcattt agattttcca agtgtaggag
      961 caacacaaaa tattattatg gcagcatcat tagctaaggg taagacttta attgaaaatg
     1021 cagctaaaga acctgaaatt gtcgatttag caaactacat taatgaaatg ggtggtagaa
     1081 ttactggtgc tggtacagac acaattacaa tcaatggtgt agaatcatta catggtgtag
     1141 aacatgctat cattccagat agaattgaag caggcacatt actaatcgct ggtgctataa
     1201 cgcgtggtga tatttttgta cgtggtgcaa tcaaagaaca tatggcgagt ttagtctata
     1261 aactagaaga aatgggcgtt gaattggact atcaagaaga tggtattcgt gtacgtgctg
     1321 aaggggaatt acaacctgta gacatcaaaa cactaccaca tcctggattc ccgactgata
     1381 tgcaatcaca aatgatggca ttgttattaa cggcaaatgg tcataaagtc gtaaccgaaa
     1441 ctgtttttga aaaccgtttt atgcatgttg cagagttcaa acgtatgaat gctaatatca
     1501 atgtagaagg tcgtagtgct aaacttgaag gtaaaagtca attgcaaggt gcacaagtta
     1561 aagcgactga tttaagagca gcagcagcct taattttagc tggattagtt gctgatggta
     1621 aaacaagcgt tactgaatta acgcacctag atagaggcta tgttgactta cacggtaaat
     1681 tgaagcaatt aggtgcagac attgaacgta ttaacgatta attcagtaaa ttaatataat
     1741 ggaggatttc aaccatggaa acaatttttg attataacca aattaaacaa attatacctc
     1801 acagacagcc atttttatta attgataaag tagttgaata tgaagaaggt caacgttgtg
     1861 tggctattaa acaagtatca ggaaacgaac cattctttca agggcatttt cctgagtatg
     1921 cggtaatgcc aggcgtatta attactgaag cgttagctca aacaggtgcg gtagctattt
     1981 taaatagtga agaaaataaa ggtaaaatcg ctttatttgc tggtattgat aaatgtcgtt
     2041 ttaaacgtca agtagtacct ggtgatactt taacgttgga agtagaaatc actaaaatta
     2101 aaggaccaat cggtaaaggt aatgctaaag ctactgtcga tggtcaactt gcttgtagtt
     2161 gtgaacttac atttgcaatt caagatgtaa aataaaacaa aaaaaacatt caaagattta
     2221 atgtgttggc ataatctttg aatgtttttt attttactct tctaattttt catcctttaa
     2281 ctttggttta gactgcatca ttcgattaaa tgattttttt aattcttcac cagataatcc
     2341 atcatcaata agttgttcta ataaactttc agcatactgt tgacgtaaag tgtaaatatg
     2401 acattcaaat acgatagaca ttgttgtttt aaaattttta atacttttca cagtagattc
     2461 aaataaagct ggatcattgg ctggacgcgt gatgacgaca cgaatatcca ataactgttc
     2521 attgtcttga tattccttaa atgtttcata atgctcatta gaaatgacaa tttcaagcaa
     2581 ccaacccgtg ccactttcct ctttattaat tattacgcca tcttctaatt catattctat
     2641 aattctgccg tgttcattca caatttgaaa ccttactgct ttaaaagttt tcatattccc
     2701 acatcccatt agtttaatat ttatgatttt tgaattattt agaagattta aggtcatttc
     2761 atgactaatt tctttaaata taacaaataa cgagatgcta tagctattaa ttatataaaa
     2821 tttgccattt tgaccatttt taagctagta attaagatat aggcatagga ggtgaatcac
     2881 acactacatg ctaaataaaa tcgtaattgt cgggagactg acgaaagacg cacaaatatt
     2941 tgaaaaggag gatagaaaaa ttgcaacgtt ttgtgttgca acgcaccgaa attataaaga
     3001 tgaaaatgga gaaatcgtct gtgattactt attctgtaaa gcatttggca agttagcttc
     3061 taatatagaa aaatatacta atcaaggtac attggttggt ataactggtc aaatgagatc
     3121 aagaaagtat gataaagacg gacaaacaca ctttgtcact gaattatatg ttgaaacaat
     3181 aaaatttatg tcccctaaat cccaaaataa tgaaattctc tcagatagta ttttagatat
     3241 tgactctcaa aatatagata atcatgactt attagaaatt taaatccaat tatcctaaac
     3301 atccttaata tacattta
//
LOCUS       DAPDIM010000125         2956 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000125 DAPDIM010000000
VERSION     DAPDIM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2956
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.131"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            135..1211
                     /locus_tag="RFE25_002751"
     CDS             135..1211
                     /locus_tag="RFE25_002751"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HDU2817763.1"
                     /translation="MSQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDADKGWH
                     DLKIVPYGPIEISPAAQGVHYGQSVFEGLKAYKRDGEVALFRPEENFKRLNNSLARLE
                     MPQVDEAELLEGLKQLVDIERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLII
                     LSPSGAYYGGETLKPTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQ
                     VLWLDGVEQKYIEEVGSMNIFFVENGKVITPELNGSILPGITRKSIIELAKNLGYEVE
                     ERRVSIDELFESYDKGELTEVFGSGTAAVISPVGTLRYEDREIVINNNETGEITQKLY
                     DVYTGIQNGTLEDKNGWRVVVPKY"
     gene            1461..2144
                     /locus_tag="RFE25_002752"
     CDS             1461..2144
                     /locus_tag="RFE25_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDU2817764.1"
                     /translation="MEWILFDKDGTLIEFDRSWEKIGVRFVQSLLETFPVHNKEAALR
                     QLGVIKESIDPKSVMGSGSLQQIIQAFNDVTGQDTTDWSKSTSQKLVDERIPEINWVE
                     GVKEALIDLKAKGYQLGIVTSDTKKGVEQFLAHTNAISLFDLIISTEADAYEKPNPKV
                     LSPLFEQYNVDPQKVAIVGDTANDMKTASNANLGMAIGVLTGIATKEELHEADIILNS
                     AADILEALN"
     gene            complement(2260..2922)
                     /locus_tag="RFE25_002753"
     CDS             complement(2260..2922)
                     /locus_tag="RFE25_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDU2817765.1"
                     /translation="MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEH
                     NPYLDKFYSDFERWSFHLQIYFLAERFKEQKRMFEYGGGFVQDRSIYEDVDIFAKMHE
                     EEGTMSKEDFKTYSDLFNAMVMTPYFPKPDVMIYLECNYDEVIDRIIERGREMEINTD
                     PEYWKKLFKRYDDWINSFNACPVVRININEYDIHKDPESLNPMIDKIARIIQTYRQVD
                     TR"
BASE COUNT         1045 a          402 c          550 g          959 t
ORIGIN      
        1 taaaagatat agtctttcta gaaaatctgt taattaattt tgaattttta gaaaatttat
       61 tgaacagcaa aatatggatt gttataattt aagttaaaca aattcttata caatattatt
      121 aggaggcaat caccatgtca caagcagtta aagttgaacg acgagaaaca ttaaaacaaa
      181 aaccaaatac atctcaacta ggttttggta aatattttac tgattatatg ttgagttatg
      241 attatgatgc agataaagga tggcatgatt tgaagatagt accttatggt cctattgaaa
      301 tttcacctgc tgcacaaggt gttcattatg gtcaatcggt attcgaagga ttaaaagcat
      361 ataaaagaga tggggaagtt gcacttttcc gtcctgaaga aaattttaag cgtcttaata
      421 actcgttagc acgattagaa atgcctcaag tagacgaagc agaattgtta gaggggctaa
      481 aacaattagt tgatatagaa agagattgga ttcctgaagg ggaaggtcaa tcattatata
      541 ttcgtccatt tgtttttgca acagaagggg cacttggcgt tggtgcatca catcagtata
      601 aattattaat tattttatct ccttcaggtg catattatgg tggtgagact ttaaaaccaa
      661 ctaaaatcta tgtagaagat gaatatgtgc gtgctgttcg tggcggtgta ggctttgcaa
      721 aagttgcagg taactatgcg gcaagtttat tagcacaaac aaatgcaaat aaattaggtt
      781 atgaccaagt attatggctt gatggtgttg aacagaaata tatcgaagaa gttggtagca
      841 tgaatatttt cttcgttgaa aatggaaaag taattacacc agagttgaat ggcagtattt
      901 tacctggtat tacacgtaaa tctattatcg aattagctaa aaacttagga tatgaagtcg
      961 aagagcgccg cgtttcaatc gatgaattat tcgaatcata tgataaaggt gagttaacag
     1021 aagtatttgg tagtggtact gcagcagtta tttcacctgt gggtacattg agatacgaag
     1081 atcgtgaaat cgttattaat aataatgaga ctggtgaaat tactcaaaaa ttatacgacg
     1141 tctatactgg tattcaaaat ggtactttag aagataaaaa tggttggaga gtcgttgtac
     1201 caaaatatta ataaaaattg aatataatca tgaaaacaat atgtaaaagt taatcatgac
     1261 taaaatccct ttcaatgaag cgaagcatgg taataaatta agtttacaat gtttattgtt
     1321 aagtattgaa ggggatttca cttattatta tatttaattc aatatttaaa tagaacaata
     1381 ctacgagttc attttcaggg gataacgaat atcatagaat cagcataata cgaaataaat
     1441 aaataggagt attgatatca atggaatgga tattatttga taaagatggt acgttaattg
     1501 aatttgatag aagttgggaa aaaatagggg tacgatttgt acaatcattg cttgagactt
     1561 tcccagtaca taataaagaa gctgctttaa gacaactcgg tgtcattaaa gaatctattg
     1621 atccaaaatc agtgatgggt tcaggatctt tacaacaaat tatccaggca tttaatgatg
     1681 tgacgggaca agatacaacc gactggtcca agtcaacaag tcaaaagctg gtagatgaac
     1741 gtattcctga aattaattgg gtagaaggtg ttaaagaagc acttatcgat ttgaaagcaa
     1801 aaggctatca acttggtatt gttacgagtg atactaaaaa aggtgtagaa caatttttag
     1861 cacataccaa tgctatctcg ttgttcgatt tgatcatttc taccgaagcg gatgcctatg
     1921 agaagccaaa tcctaaagta ttatcgcctt tatttgagca atataatgta gatcctcaga
     1981 aagtagctat agtaggagac actgctaatg atatgaagac agcaagtaat gcaaatttag
     2041 gtatggcaat aggtgtatta acaggtattg caacaaaaga agaattacat gaagctgata
     2101 ttattttaaa tagtgcggca gatattttag aagctttaaa ttaaaaagaa agacatagtg
     2161 tatatgtgaa ttaatgtatt cgatagaatt gataatgtaa tcgatgatat ctatggaata
     2221 tacattgaat ataaacatat acgctatgtc tttagtcttt tatcgtgtat ctacttgtcg
     2281 atatgtttga ataattcgag caattttgtc tatcatagga tttaaagatt cggggtcctt
     2341 atggatatca tattcattaa tattgatacg tacaactgga catgcattaa agctattaat
     2401 ccaatcgtca tagcgtttaa atagcttttt ccagtattca gggtctgtat taatttccat
     2461 ttcgcgacca cgttcaataa tacgatcaat gacctcatca tagttacatt ctaaataaat
     2521 cattacatct ggtttaggaa aataaggtgt catgaccatg gcattaaata agtctgaata
     2581 tgttttgaaa tcttctttac tcattgtgcc ttcttcttca tgcatttttg caaaaatatc
     2641 aacatcttca taaattgatc gatcttggac aaagccacca ccatattcaa acatacgctt
     2701 ttgttcttta aaacgttcag ctaagaagta aatttgcaaa tggaaactcc atcgttcaaa
     2761 atcgctataa aatttatcta aatatggatt atgttcgaca ttttcaaaag acgttttaaa
     2821 gtttaattta tctgcaagtg cttgcgttag tgttgatttt ccaacaccaa ctgtacctgc
     2881 aatggttata atggcatttt gtggaatacc gtaattattc attggtaata tctcctatca
     2941 taggtaatat aatatg
//
LOCUS       DAPDIM010000126         2842 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000126 DAPDIM010000000
VERSION     DAPDIM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2842
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.132"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..94
                     /locus_tag="RFE25_002754"
     CDS             <1..94
                     /locus_tag="RFE25_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817766.1"
                     /translation="KDISNVLECSEQSVRLWYETLLDKIVEVIE"
     gene            91..660
                     /locus_tag="RFE25_002755"
     CDS             91..660
                     /locus_tag="RFE25_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDU2817767.1"
                     /translation="MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLK
                     KPHIKQYIQEQKDKIIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSG
                     KVQLVYNEHVELIEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGD
                     DEELDKAVKDVSNANPNHTVIVDDIPLED"
     gene            875..1447
                     /locus_tag="RFE25_002756"
     CDS             875..1447
                     /locus_tag="RFE25_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002459634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817768.1"
                     /translation="MCTTIDIRGYHGTDRSCYDNLEINKEFPVNKLPSDLGNGLYLFI
                     DRKNKVGEAIKNAKNYLDRWKPKYEKKIIAQIDIKVKENRLMDLDDHDNQYEFNSFVE
                     ENEETIYNELDKLINNNTKSRGNIDGLIIEIMIREYNLEIDAIQKETYTQFDKSKKRK
                     RSNIPNGKELCIRQNDIIKNKCIYNENVVT"
     gene            1468..1764
                     /locus_tag="RFE25_002757"
     CDS             1468..1764
                     /locus_tag="RFE25_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002459633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusB"
                     /protein_id="HDU2817769.1"
                     /translation="MGLKLKEYINDSNRKLDKETVRKHLVDILNYTVEENSFLDQMTV
                     GKRLYSNQYKNSPSVSLTVNHKIKINEVTSDFSYKFSDNETQTFNLSNELGVVA"
     gene            1764..2204
                     /locus_tag="RFE25_002758"
     CDS             1764..2204
                     /locus_tag="RFE25_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HDU2817770.1"
                     /translation="MASIGFKTYNFNHISYSKNKELDIENVDTFEVNSDFSAKVAFEN
                     EEAYIIMDCQIGNNKPNCPFIINMQLTGVFDIEYENDVEDKNSLKILLTQNAIAILYP
                     YIRSLVSDLTSKANMFDTFIMPVVNVAKMMEENNRIEIVGLDKK"
     gene            2510..>2842
                     /locus_tag="RFE25_002759"
     CDS             2510..>2842
                     /locus_tag="RFE25_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817771.1"
                     /translation="MNNIGIIITIIGTILTVFNTISAIRWRRRNYNYRKQIDYYKNEL
                     EEANQKYIKNLNNKKELTEFINNFVKLSYSTIMSCISFLYTLDFITKSLTKNNEYISQ
                     EKLEKLLQR"
BASE COUNT         1168 a          284 c          509 g          881 t
ORIGIN      
        1 taaagatatt agcaatgtct tagagtgttc agaacaatct gtaagattat ggtatgaaac
       61 cttattagat aaaattgtgg aggtgataga atgagtgagt taacggcaaa acaagcgcgt
      121 tttgtgaatg agtatataag aacacttaat gtaacacaaa gtgccataaa agcaggctat
      181 agcgcaaata gcgcacatgt gacagggtgt aggttattga agaagccaca catcaagcaa
      241 tatatacaag aacaaaaaga taagattata gatgagaatg tattaaccgc aaaagagtta
      301 ctacatgtgc ttacgaatgc ggcagtcggt gatgaaacag aaacgaaaga agttgtagta
      361 aagcgtggag aatataaaga gaatccacaa agtggcaaag tacaattagt ctataatgaa
      421 catgttgaac tgatagaggt accaataaaa cctagtgatc gtttaaaagc tcgtgatatg
      481 ttggggaaat accataagtt atttacagat aagcatgata ttaacgggaa tgtccctata
      541 ttcattaata ttggtgaatg ggacggagac gatgaggaat tagataaggc agtgaaagat
      601 gtatctaacg ctaatcctaa tcatactgtg attgtggatg atattccgtt agaggattaa
      661 tgaggaatat ttacagataa actagatgtg agtcttgtga caccagaaat tgttgatgat
      721 ataggtgggt ttgaggagta atgtaaatag acgccaagcc tatgcgattt agcgtttatt
      781 agactttatg atagtgatta aaagtaaaag gctttataat ctgcttgtat agttgtataa
      841 ttaaacccaa ttgtttttca taaggagtat tactatgtgc acaacaatag atataagggg
      901 ttatcatggt acagatagaa gttgctatga taatttagaa ataaataagg aattccctgt
      961 taataaatta ccatctgatt taggtaatgg tctttatcta tttatagaca gaaaaaataa
     1021 ggttggagaa gcaattaaaa atgctaaaaa ttatttagat agatggaaac caaaatatga
     1081 gaaaaaaatc attgcacaaa tagatataaa agtaaaagag aatagattga tggatttaga
     1141 tgatcatgat aatcaatatg aatttaattc attcgttgaa gaaaatgaag aaacaatata
     1201 caatgaatta gataagttga ttaataataa tacaaaaagt cgaggtaata tagacggctt
     1261 aataattgag attatgatta gagagtataa tcttgaaatt gatgctatcc aaaaagaaac
     1321 ttatactcaa tttgataaaa gcaaaaaaag aaaaagatct aacataccta acggtaaaga
     1381 actttgtata agacagaatg atattattaa gaataagtgt atttataatg aaaatgtggt
     1441 aacttaatat aagtagaggt gatataaatg ggtttgaaat taaaagagta tataaatgat
     1501 agtaatagga aattggataa agaaacagtt agaaagcact tagtagatat actaaattac
     1561 actgttgaag aaaatagttt tctagatcaa atgacagttg gtaaaagact atattcaaat
     1621 caatataaaa actcgccctc tgtatcatta actgtaaatc ataaaattaa aataaatgaa
     1681 gtgacgagtg attttagcta taaattttct gataatgaaa ctcaaacttt taatctttca
     1741 aatgagttag gagtagtagc gtaatggcta gtataggttt caaaacttac aactttaatc
     1801 atattagtta tagtaaaaat aaagaattag atattgaaaa tgttgatact tttgaagtga
     1861 atagtgattt ttctgcaaaa gtagcctttg aaaatgaaga agcttacatt ataatggact
     1921 gccaaatagg taataataaa cccaattgtc cgtttattat aaatatgcaa ttaacaggag
     1981 tctttgatat cgaatatgaa aacgatgttg aagataaaaa tagtttaaaa atattactca
     2041 cacaaaatgc tattgcaatt ttatatcctt atattcgtag tttagtatct gatctcacat
     2101 cgaaagcaaa tatgtttgat acttttataa tgcctgttgt taatgttgct aagatgatgg
     2161 aggaaaataa tagaattgaa attgttggct tggataaaaa atagtgattt ttagaaaaat
     2221 aataattatg aaaactaaat gattaatgaa tactaagcta acttaaaaac gccacttatt
     2281 tgtggcgttt tttgtgtata aaacggagtt ctatattata ttggtttata tctcatgttt
     2341 tgggaacata atttaatcta gaagaaaaat atgatggtaa aaataatcaa tgataggatt
     2401 aatgtatgat attcagtagt tttaagcaaa gaatctaaac aaattggatt aggctatttt
     2461 gtagtttcta tttataatgt taaaatttta ctaaaaaggt gggggataaa tgaataatat
     2521 tggaataata ataactataa tagggactat tttaactgtg tttaatacta tttctgcaat
     2581 taggtggaga agaaggaatt ataattatcg caaacaaata gattattata aaaatgaact
     2641 cgaagaagca aatcagaaat atatcaaaaa tttaaacaat aaaaaagaac tgacagaatt
     2701 tattaataat tttgttaaat taagttattc tacaataatg tcgtgtatca gttttttata
     2761 tacactagat tttattacta aaagtcttac caaaaacaac gaatatataa gtcaggaaaa
     2821 actagaaaaa ttattacaaa ga
//
LOCUS       DAPDIM010000127         2772 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000127 DAPDIM010000000
VERSION     DAPDIM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2772
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.133"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..525
                     /locus_tag="RFE25_002760"
     CDS             <1..525
                     /locus_tag="RFE25_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002955256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1672 family protein"
                     /protein_id="HDU2817772.1"
                     /translation="SNDNGDDMSMMVGTVLSGFEYRAQKEKYDNLYKFLKENEKKYQY
                     TGFTKEAINKTQNVGYQNEYFYITYLSRNLKEYRKYYEPLIHKKDKEFKEGMQRARKE
                     LNYTANTDVVSTLFSTKKNFTKDNTVDDVIELSNKLKDKPNMPQKSQVTIQLGKPSIN
                     TKKPFYDDINPIEG"
     gene            537..942
                     /locus_tag="RFE25_002761"
                     /pseudo
     CDS             537..942
                     /locus_tag="RFE25_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829176.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            996..1952
                     /locus_tag="RFE25_002762"
     CDS             996..1952
                     /locus_tag="RFE25_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1672 domain-containing protein"
                     /protein_id="HDU2817773.1"
                     /translation="MLKKAKLILIAALVLSGCSTIENESKKDRNTETNTETKSVPEEM
                     EASKYVGQGFQPPAEKDAIEFAKKHKDKIAKRGEQFFMDNFGLKVKATNVVGSGDGVE
                     VYVHCDDHDIVFNASIPFDKSIIDSDSSLRSEDKGDDMSTLVGTVLSGFEYRAHKEEL
                     DNLTEVLKEYKSKYKYTGYTENAIMKTQNSGFRNEYYYLTAIPYTLDEYKRYFQPLIK
                     EDDKSFRDGMRNSKKQLKDKSRPYVVTTLFSTKDNFTKDNTIDEMIDFSEVLKKKKNI
                     PHDLNVSLQISNKYINTKRPNYSKKEVIEVGVFNHEKANTND"
     regulatory      2158..2292
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            2354..>2772
                     /locus_tag="RFE25_002763"
     CDS             2354..>2772
                     /locus_tag="RFE25_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDU2817774.1"
                     /translation="MQQNKRLITISMLSAIAFVLTFIKFPIPFLPPYLTLDFSDVPSL
                     LATFTFGPVAGIVVALVKNLLNYLFSMGDPVGPFANFLAGASFLLTAYAIYKNKRSTK
                     SLITGLIIATIVMTIVLSILNYFVLLPLYGMIFNLAD"
BASE COUNT         1100 a          360 c          489 g          823 t
ORIGIN      
        1 agtaatgaca acggtgatga tatgagtatg atggtgggta cagtgctgag tggctttgaa
       61 tatcgagcgc aaaaagaaaa gtatgataat ttatataaat ttttaaaaga aaatgaaaag
      121 aaatatcaat atacaggttt tactaaagaa gcaattaaca agacgcaaaa cgtcgggtat
      181 caaaatgaat atttttatat tacatattta tcaagaaatt taaaagaata tcgtaaatat
      241 tacgaaccat tgattcataa aaaggataaa gaatttaaag aaggtatgca acgagctaga
      301 aaagagctaa actatactgc taatactgat gttgtttcta cacttttttc tactaagaaa
      361 aactttacta aagacaatac agtagatgat gtgattgaat tgagtaataa attaaaagat
      421 aaacccaata tgcctcaaaa atctcaagtt actattcaat taggaaaacc aagtataaat
      481 actaaaaagc cgttttatga cgatataaat ccaattgaag gatgagtgaa tataaagtga
      541 ttaaaataaa tgatagagac atagcagaat tgagcagata ttgagtttat caagatataa
      601 atgaaaaaag attttaaagt aaatggaaaa cggttcaaac aaatagatta ttttaatgat
      661 aaaaataacg ataatatgaa agatgcagtt gatataaaaa cctacgagct acttaatgat
      721 cagggagatc caactggtca aaagacaata atatatcaag gaacatctaa agaggcaatt
      781 aatccaaata atccattaaa atcatcgggt tttggagatg attggcttca aaatgctaaa
      841 ttaatgaata attaaattaa aataatagat tttttaacgc aagtatatgt acttgaagat
      901 ttatatatag gtgaactaaa agatgcaaat aaattaagtg agtataacta tatgcaaaat
      961 gaaacttata aaagcgcata aatgggtgat gagatatgct taaaaaagca aaattaatct
     1021 taatagcagc actagtactg tcagggtgct ccacgattga aaatgaatca aaaaaagaca
     1081 gaaatacaga aacaaataca gaaacgaaat ctgtaccaga agaaatggaa gcttcaaaat
     1141 atgtaggcca aggattccaa ccgcctgcag aaaaagatgc gattgaattt gcgaagaagc
     1201 ataaagataa aattgctaaa cgtggcgaac aattttttat ggataacttc ggtctaaaag
     1261 ttaaagctac gaatgttgta ggtagtggcg acggcgtaga agtatacgtg cattgtgatg
     1321 accacgatat cgtatttaat gcgagtattc catttgacaa atcaattatt gacagtgata
     1381 gctcattaag aagtgaggat aaaggcgatg atatgagtac tttagttggt acagtgttga
     1441 gtggttttga atatcgagca cataaggaag agttggataa tttaacagaa gttttaaaag
     1501 aatataaaag taaatataaa tatactggtt atactgaaaa tgcaattatg aaaacgcaga
     1561 atagtggttt tagaaatgag tattattatt tgactgcaat tccatatact ttagatgaat
     1621 ataaaaggta ttttcaaccc ttaatcaaag aggatgataa gtcttttagg gacggtatga
     1681 gaaactcaaa aaaacaactt aaagataaat cacgtccata tgttgttaca actttattta
     1741 gtactaaaga taattttact aaagataata caatagacga gatgattgat ttttctgaag
     1801 tactaaaaaa gaaaaagaat attcctcatg atttgaatgt ttctcttcaa atttctaata
     1861 aatatataaa tacaaaaaga cctaactata gtaagaagga agtaatagaa gtaggtgtat
     1921 ttaatcatga aaaagctaac acgaatgatt aaactaataa caataaaaag gtaggttcaa
     1981 aaaagccatc tcaacaacag ttaaaaccac aaaccaatca aacctatcca accaatgaac
     2041 tcaaatcacc aatgtatcac tctccaataa tgtaactatg atctaattaa agcatagtta
     2101 ttgaggtttt gtgatatata gtataaaatt aatgagaatt aaatttaata atgtaaaatt
     2161 catcttcggg gtcgggtgta attcccaacc ggcagtaaat aaagcctgcg acctgctagt
     2221 atgtatcata ttagtggctg atctagtgag attctagagc cgacagtata gtctggatgg
     2281 gagaagatgg aggttttttg ttgtgcaata atcctcctat tcttacgaga tgaatggaag
     2341 gagaaaattg aatatgcaac aaaataaacg tcttatcaca ataagtatgt tgagcgcgat
     2401 tgcgtttgtg ttaactttta tcaagtttcc tataccattt ttgccaccat acttaacttt
     2461 agattttagt gatgtaccgt cactactagc tacatttacg tttggaccag ttgccggtat
     2521 cgtagttgca ctggttaaaa acttgctgaa ctacttattt agtatgggcg atccagttgg
     2581 gccgtttgct aactttttag caggcgcaag tttcttatta actgcttacg ccatctataa
     2641 aaataaacgt tcaacaaaat ctttgattac tggattaatc attgcaacaa tcgttatgac
     2701 tatcgtgttg agtattttga actatttcgt tctattacct ttgtacggta tgatatttaa
     2761 cttagctgat at
//
LOCUS       DAPDIM010000128         2744 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000128 DAPDIM010000000
VERSION     DAPDIM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2744
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.134"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..1416
                     /locus_tag="RFE25_002764"
     CDS             <1..1416
                     /locus_tag="RFE25_002764"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HDU2817775.1"
                     /translation="SKIDPVNIVGIGIDFTSSTIIFTDENLNPVHNLKQFKNNPHAYV
                     KLWKHHGAYKEAEKLYQTAIENNNKWLGHYGYNVSSEWMIPKIMEVMNRAPEIMEKTA
                     YIMEAGDWIVNKLTNKNVRSNCGLGFKAFWEEETGFHYDLFDKIDPKLSKVIQDKVSA
                     PVVNIGEVVGKLDDKMAQKLGLSKETMVSPFIIDAHASLLGIGSEKDKEMTMVMGTST
                     CHLMLNEKQHQVPGISGSVKGAIIPELFAYEAGQSAVGDLFEYVAKQAPKSYVDEAAN
                     RNMTVFELMNEKIKHQMPGESGLIALDWHNGNRSVLSDSNLTGCIFGLTLQTKHEDIY
                     RAYLEATAFGTKMIMQQYQDWHMEVEKVFACGGIPKKNAVMMDIYANVLNKKLIVMDS
                     EYAPAIGAAILGAVSGGAHNSINDAVDAMKEPILYEINPEAEKVQRYETLFKAYKALH
                     DIHGYKKANIMKDIQSLRVEG"
     gene            1630..2595
                     /locus_tag="RFE25_002765"
     CDS             1630..2595
                     /locus_tag="RFE25_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDU2817776.1"
                     /translation="MKKIMITGALGQIGTELVVKCREIYGTDNVLATDIREPEADSPV
                     QNGPFEILDVTDRDRMFELVRDFEADSLMHMAALLSATAEKNPILAWDLNMGGLMNAL
                     EAARTYNLHFFTPSSIGAFGDSTPKVNTPQVTIQQPTTMYGVNKVAGELLCQYYFKRF
                     GVDTRSVRFPGLISHVKEPGGGTTDYAVEIYFKAVREGHYTSFIDKGTYMDMMYMDDA
                     IEAIIKLMEADDAKLETRNGYNLSAMSFDPEMVKEAIQEYYPNFTLDYDVDPIRQGIA
                     NSWPDSIDTSCSRGEWGFDPKYDLASMTKLMLEAIEQKDTVKNNN"
BASE COUNT         1018 a          356 c          547 g          823 t
ORIGIN      
        1 tcaaaaatag atccagtcaa tatagtaggt attggtatag actttacttc atctactatt
       61 atttttactg acgaaaacct taacccggta cataatttaa aacaatttaa aaacaatcca
      121 catgcgtatg tgaaactttg gaaacatcat ggtgcatata aagaagcaga gaaattatat
      181 caaactgcta ttgaaaataa taataagtgg ttaggccatt atggatataa tgttagtagt
      241 gaatggatga ttcccaaaat aatggaagtc atgaatcgag caccagaaat tatggaaaaa
      301 acggcttata ttatggaagc gggcgattgg attgtaaata aattaactaa taaaaatgta
      361 cgctcgaatt gtggattagg tttcaaagca ttttgggaag aagaaacagg gtttcattat
      421 gatttatttg ataaaataga ccccaaatta tcaaaagtaa ttcaagataa agtatctgca
      481 ccggttgtta atattggtga agtagtaggg aaactggacg ataaaatggc acagaaatta
      541 ggattatcaa aagagactat ggtaagtcct tttattattg atgcccatgc tagtttatta
      601 ggtattgggt ctgaaaaaga taaagaaatg actatggtga tgggaacaag cacatgccat
      661 cttatgttaa atgaaaagca acatcaagtg ccaggtatat caggttctgt aaaaggagca
      721 attattccag aattatttgc ttatgaagcg gggcaatcag cagtaggtga tttgtttgag
      781 tatgtcgcta agcaagcacc aaagtcatat gtagatgaag cagcaaatag aaatatgact
      841 gtatttgaat taatgaatga aaagataaaa catcaaatgc caggtgaaag tgggctcatt
      901 gctcttgatt ggcataatgg aaatcgaagt gtattaagtg atagcaattt aacaggttgt
      961 atctttggat taactttaca aactaagcat gaggatattt atagagcata tttagaagct
     1021 acagcatttg gtactaagat gattatgcaa cagtatcaag attggcatat ggaagtagaa
     1081 aaggtatttg catgtggcgg tatacctaaa aagaatgctg ttatgatgga tatctatgcg
     1141 aatgtactga ataaaaaact aattgttatg gatagtgagt atgcaccagc aataggcgca
     1201 gcaatattag gtgcagtcag tggtggcgca cataattcaa ttaatgatgc agttgatgct
     1261 atgaaagagc caattttata cgaaattaat ccagaagcgg aaaaagtaca aaggtatgaa
     1321 acattattta aagcttataa ggctttacat gatatccatg gttataaaaa agctaatata
     1381 atgaaagata tccagagttt aagagttgag ggataaaaaa tttaatttga cagtaattag
     1441 caataataaa cgctataaat tactaaaatc aattaataca actagaattt ccatttacag
     1501 aaacatcagc aacatgtaca tgtcatatat acaagaaagc gcttttatat tataattatt
     1561 atgaaaatga atattatgtc cgcttgtgac ggactatagc tatatagaag agacaaagga
     1621 gatatttcta tgaaaaaaat tatgattact ggtgcattag gacaaattgg tacagaatta
     1681 gttgttaagt gcagagaaat ttatgggaca gataatgttc ttgctacaga tattagggaa
     1741 cctgaagcag actcacctgt acaaaatgga ccatttgaaa ttttagacgt aacagatcgt
     1801 gaccgcatgt ttgagttagt tagggacttt gaagcggata gtctaatgca tatggcagca
     1861 ttattatcag caactgcaga gaaaaatcca attctagctt gggatttaaa tatgggtgga
     1921 ttaatgaatg cattagaagc tgcaagaact tataatttgc actttttcac accaagttca
     1981 attggtgcat ttggagactc aactcctaaa gttaatacgc cacaagtaac gattcagcaa
     2041 cctacgacaa tgtatggtgt aaataaagta gctggagaat tattgtgtca atactatttc
     2101 aaacgttttg gtgtagatac aagaagtgtt agattcccag gtttaatctc gcatgttaaa
     2161 gagccaggtg gcggtactac agactatgct gttgaaatat acttcaaagc agtaagagag
     2221 ggtcattata caagcttcat agataaaggc acgtatatgg atatgatgta tatggatgat
     2281 gcaattgaag caattattaa acttatggaa gcagacgacg ctaaattaga aactagaaac
     2341 ggttataatt tgagcgcaat gagttttgat ccagagatgg taaaagaagc aattcaagaa
     2401 tactatccaa attttacatt agattatgat gttgatccta ttagacaagg tatcgctaat
     2461 agttggccgg attctattga tacaagctgt tcacgtggcg aatggggatt tgatcctaaa
     2521 tatgatttag cgagcatgac taaattaatg ttagaagcta ttgaacaaaa agatactgtt
     2581 aaaaataata actaatcatt tccattcact ttaatacacg gaatgatatt ttaaattact
     2641 ctttatttta ataaactagt gcatgaattc taatattatt cattatacat attgaattcg
     2701 cgagcttagt tcattttaaa gtaaagagtt ttttgtatgt aaag
//
LOCUS       DAPDIM010000129         2631 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000129 DAPDIM010000000
VERSION     DAPDIM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2631
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.135"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            35..1909
                     /locus_tag="RFE25_002766"
     CDS             35..1909
                     /locus_tag="RFE25_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016187665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDU2817777.1"
                     /translation="MGLPNPKTRKPTASEVVEWAKSNIGKRINIDNYRGSQCWDTPNF
                     IFKRYWGFVTWGNAKDMANYRYPKGFRFYRYSSGFVPEPGDIAVWHPGNGIGSDGHTA
                     IVVGPSNKSYFYSVDQNWVNSNSWTGSPGSLVRHPYVSVTGFVRPPYSKDTSKPSSTD
                     TSSASKANDSTITGEAKKPQFKEVKTVKYTAYSNVLDKEEHFIDHIVVMGDERSDIQG
                     LYIKESMHMRSVDELYTQRNKFISDYEIPHLYVDREATWLARPTNFDDPRHPNWLVIE
                     VCGGQTDSKRQFLLNQIQALIRGVWLLSGIDKNLSETTLKVDPNIWRSMKDLINYDLI
                     KQGIPDNAKYEQVKKKMLETYIKRDILTRENIKEVTTKTTIRISDKTSVDSASTRGPT
                     PSDEKPSIVTETSPFTFQQALDRQMSRGNPKKSHTWGWANATRAQTSSAMNVKRIWES
                     NTQCYQMLNLGKYQGISVSALNKILKGKGTLDGQGKAFAEACKKNNINEIYLIAHAFL
                     ESGYGTSNFANGRYGAYNYFGIGAFDNDPDYAMTFAKNKGWTSPAKAIMGGASFVRKD
                     YINKGQNTLYRIRWNPKNPATHQYATAIEWCQHQASTIAKLYKQIGLKGIYFTRDKYK
                     "
     gene            1922..>2631
                     /locus_tag="RFE25_002767"
     CDS             1922..>2631
                     /locus_tag="RFE25_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HDU2817778.1"
                     /translation="MYKIKDVETRIKNDGVDLGDIGCRFYTEDENTASIRIGINDKQG
                     RIDLKAHGLTPRLHLFMEDGSIFKNEPLIIDDVVKGFITYKIPKKVIKHAGYVRCKLF
                     LEKEEEKIHVANFSFNIVDSGIESAVAKEIDVKLVDDAITRILKDNATDLLSKDFKEK
                     IDKDVISYIEKNESRFKGAKGDKGEPGQPGAKGEAGKKGEQGAPGKNGTVVSINPDTK
                     MWQIDGKDTDIKAEPELL"
BASE COUNT          968 a          425 c          558 g          680 t
ORIGIN      
        1 tggcttttta ttttgattga aatgaggtgc atacatggga ttacctaacc caaagactag
       61 aaagcctaca gctagtgaag tggtggagtg ggcaaagtcg aatattggta agaggattaa
      121 tatagataat tatcggggca gtcaatgttg ggatacacct aactttattt ttaaaagata
      181 ttggggtttt gtaacatggg gcaatgctaa ggatatggct aattacagat atcctaaggg
      241 tttccgattc tatcgttatt catctggatt tgtaccggaa cctggagaca tcgcagtttg
      301 gcaccctggc aacggaatag gttcggacgg acacaccgca atagtagtag gaccatctaa
      361 taaaagttat ttttatagcg ttgaccaaaa ctgggttaat tctaatagtt ggacaggttc
      421 tccgggaagt ttagtaagac acccttatgt aagtgttaca ggctttgtca gacctccata
      481 ttcaaaagat actagcaaac ctagtagtac tgatacaagt tcagcatcaa aagccaatga
      541 ctcaacaatt actggcgaag cgaagaaacc gcaatttaaa gaagttaaaa cagtaaaata
      601 cactgcttac agcaatgttt tagataaaga agagcacttc attgatcata tagttgtaat
      661 gggtgatgaa cgctcagata ttcaaggatt atatataaaa gaatcaatgc atatgcgttc
      721 tgtagacgaa ctgtatacgc aaagaaataa gtttataagc gattatgaaa taccgcattt
      781 atatgtcgat agagaggcta catggcttgc tagaccaacc aattttgatg acccgcgtca
      841 ccctaattgg ctagttattg aagtatgtgg tggtcaaaca gatagcaaac gacaattctt
      901 attgaatcaa atacaagcgt taatacgtgg tgtttggtta ttgtcaggga ttgataaaaa
      961 cttatctgaa acgacgttaa aggtagaccc taatatttgg cgtagtatga aagatttaat
     1021 taattacgac ttgattaagc aaggtatacc ggataacgca aagtatgagc aagttaaaaa
     1081 gaaaatgctt gagacataca ttaaacgaga tatattgaca cgagaaaata taaaagaagt
     1141 aacgacaaaa acaacaataa gaattagtga taaaacatca gttgatagtg cgtccacacg
     1201 aggccctact ccatcagacg aaaaaccaag catcgttact gaaacaagtc cattcacatt
     1261 ccagcaagca ctggatagac aaatgtctag gggtaacccg aaaaaatctc atacatgggg
     1321 ctgggctaat gcaacacgag cacaaacgag ctcggcaatg aatgttaagc gaatatggga
     1381 aagtaacacg caatgctatc aaatgcttaa tttaggcaag tatcaaggca tttcagttag
     1441 tgcgcttaac aaaatactta aaggaaaagg aacgctcgac ggacaaggca aagcattcgc
     1501 ggaagcttgt aagaaaaaca acattaacga aatttatttg atcgcgcacg ctttcttaga
     1561 aagtggatac ggaacaagta acttcgctaa tggtagatac ggtgcatata attacttcgg
     1621 tattggtgca ttcgacaacg accctgatta tgcaatgacg tttgctaaaa ataaaggttg
     1681 gacatctcca gcaaaagcaa tcatgggcgg tgctagcttc gtaagaaagg attacatcaa
     1741 taaaggtcaa aacacattgt accgaattag atggaatcct aagaatccag ctacccacca
     1801 atacgctact gctatagagt ggtgccaaca tcaagcaagt acaatcgcta agttatataa
     1861 acaaatcggc ttaaaaggta tctacttcac aagggataaa tataaataaa gaggtgtgta
     1921 aatgtacaaa ataaaagatg ttgaaacgag aataaaaaat gatggtgttg acttaggtga
     1981 cattggctgt cgattttaca ctgaagatga aaatacagca tctataagaa taggtatcaa
     2041 tgacaaacaa ggtcgtatcg atctaaaagc acatggctta acacctagat tacatttgtt
     2101 tatggaagat ggctctatat tcaaaaatga gccccttatt atcgacgatg ttgtaaaagg
     2161 attcattacc tacaagatac ctaaaaaggt tatcaaacac gctggttatg ttcgttgtaa
     2221 gctgttttta gagaaagaag aagaaaaaat acatgtcgcg aacttttctt tcaatatcgt
     2281 tgatagtggt attgaatctg ctgtagcaaa agaaatcgat gttaaattgg tagatgatgc
     2341 tattacgaga atcttaaaag ataacgcgac agatttattg agcaaagact ttaaagagaa
     2401 aatagataaa gatgttattt cttacatcga aaagaatgaa agtagattta aaggtgcgaa
     2461 aggtgataaa ggcgaaccgg gacaacctgg tgcaaaaggt gaagcaggta aaaaaggaga
     2521 acaaggtgca cccggtaaga acggtactgt agtatcaatc aatcctgaca ctaaaatgtg
     2581 gcaaattgac ggtaaagata cagatatcaa agcagaacct gagttattgg a
//
LOCUS       DAPDIM010000130         2593 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000130 DAPDIM010000000
VERSION     DAPDIM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2593
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.136"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(145..1188)
                     /gene="recA"
                     /locus_tag="RFE25_002768"
     CDS             complement(145..1188)
                     /gene="recA"
                     /locus_tag="RFE25_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDU2817779.1"
                     /translation="MDNDRQKALDTVIKNMEKSFGKGAVMKLGDNIGRRVSTTSTGSV
                     TLDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQSNGGVAAFIDAEHALDPEY
                     AQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGD
                     THVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYS
                     SVRLEVRRAEQLKQGQEIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDL
                     GVENDIVDKSGAWYSYNGERMGQGKENVKMYLKENPQIKEEIDRKLREKLGISDGDVE
                     ETEDAPKSLFDEE"
     gene            complement(1353..2504)
                     /locus_tag="RFE25_002769"
     CDS             complement(1353..2504)
                     /locus_tag="RFE25_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CinA family nicotinamide mononucleotide
                     deamidase-related protein"
                     /protein_id="HDU2817780.1"
                     /translation="MSIAIIAVGSELLLGQIANTNGQFLSKVFNEIGQNVLEHKVIGD
                     NKKRLESSVRHALEKYDTVILTGGLGPTKDDLTKHTVAQIVGKDLVIDEPSLKYIESY
                     FEEQGQEMTPNNKQQALVIEGSTVLANHHGMAPGMMVNFENKQIILLPGPPKEMQPMV
                     KNELLSHFINHNRIIHSELLRFAGIGESKVETILIDLIDKQTNPTIAPLAGSHEVYIR
                     LTANADSKEQAQSLIQPVKQEILDRIGEYYYGSDDTLIEQAVIKKIHEPFVIYDGITN
                     GALYHRLKEVDLNDVLKGMINHNENFVDINKPIEQQLKDAVQFVNKLFNVSSAIILLE
                     YDGVVHIGYDNNFEFKTEQFKMSKSRNLLKNRSQNYVLIRLLNWLRTTN"
BASE COUNT          797 a          501 c          342 g          953 t
ORIGIN      
        1 aaataaaata aaaaacctta tagtctcgat ttgtagtgta tcccataaag ttagatatta
       61 ttctagcttt atgagatgaa tatcactttc aatcaatcct ataaggatat ttgctaagtt
      121 taactataga tataaatttg tgtactattc ttcgtcaaat aatgactttg gtgcatcttc
      181 tgtttcttca acatcaccat cagatatacc taatttttct ctcaatttac gatcaatttc
      241 ttctttaatt tgtggatttt ctttcaagta cattttaaca ttttccttac cttgacccat
      301 tcgttcgcca ttgtaagaat accatgctcc tgatttatca acgatgtcgt tttcaacacc
      361 taaatcaata agttcaccct ctttagaaat accttgtcca tacataatat caacttcagc
      421 tactctaaat ggtggtgcca ctttattttt aacgacttta attttagttc tattacctac
      481 aatttcttgt ccttgtttaa gctgttctgc acgacgtact tctagtctta ctgaactata
      541 gaattttaat gcacgtccac ctggtgtagt ctctggatta ccgaacataa caccaacttt
      601 ttcacgaatt tggttgatga aaatagcagt tgtatttgat ttagaaatag cacctgaaag
      661 tttacgtaac gcttgtgaca ttaaacgagc ttgtaaacca acgtgagtgt ctcccatttc
      721 tccttcaatt tcagctttag gtgttaaagc agcaactgag tctacaacta caatatcaac
      781 tgcaccactt ctaacaaatg cttcggcgat ttcaagacct tgttcaccat gatccggttg
      841 cgataaatat aaattatcga tatctacgcc taatgcttga gcatattctg gatctaaagc
      901 atgttcagca tcgataaatg ctgccacccc gccattactt tgtacttcag caatagcgtg
      961 aagcgctact gttgtcttac cagaactttc aggaccataa atttcaataa ttcgtccttt
     1021 aggatagcca cctacaccta gcgcattatc taatgtaact gaaccagttg atgtagttga
     1081 aactcggcga cctatattgt cacccaactt cattacggca cctttaccga aagatttctc
     1141 catattttta attactgtat ctaaagcttt ttgacgatcg ttatccaaag cgagacctcc
     1201 taattgaaat tgctatcttt taattatctt atcaatacta tacaaggatt caaaataaaa
     1261 tacaagtgtt ttgcgaatat ttgttcgtat aaaatcttga aatcaaaacg caaaaacgaa
     1321 caaacgtgct tatattttta tcgataatac aattaatttg ttgttctaag ccaatttaat
     1381 aatcttatga gcacataatt ttgacttctg ttctttaata aatttctaga tttagacatt
     1441 ttaaattgct cagttttaaa ttcaaagtta ttatcatagc ctatatggac tacaccatca
     1501 tactctaata gaataattgc tgatgacaca ttaaacaatt tattaacaaa ttgcactgca
     1561 tcttttaatt gctgctcaat aggtttatta atatcaacaa agttttcatt gtgattaatc
     1621 atacccttta gaacatcgtt taaatccact tctttcaatc gatgatataa agcaccatta
     1681 gtaataccat catatattac aaaaggttca tgaattttct ttattacagc ttgctcaatt
     1741 aatgtgtcat ctgaaccata ataatattct ccaatacgat caagaatttc ttgtttaaca
     1801 ggttgaatca atgattgtgc ttgttctttt gagtcggcat ttgcagtcaa tctaatatat
     1861 acttcatgac ttcccgccaa aggcgcaatc gtaggattag tctgtttatc gataagatct
     1921 attaatattg tttctacttt agattcacct attcccgcaa atcttaatag ttcagaatgt
     1981 ataattcgat tatggtttat aaaatgtgac aacaattcat ttttcaccat tggttgcatt
     2041 tctttcggtg gacctggtaa taaaataatt tgtttgtttt caaaattcac catcattcct
     2101 ggagccatgc catgatgatt tgctaataca gttgaacctt caattactaa agcctgttgt
     2161 ttattattag gtgtcatttc ttgtccttgt tcctcaaaat agctttcaat atattttaaa
     2221 gaaggctcat caataactaa atctttacca acaatctggg ccactgtatg cttcgttaag
     2281 tcatctttcg taggacctaa gccacctgtt aaaataacag tatcatattt ttctaacgca
     2341 tgacgtacac ttgattctaa acgtttttta ttatctccaa taactttatg ttctaataca
     2401 ttttgtccaa tttcattaaa tactttagat agaaattgtc cgttggtatt agcgatttga
     2461 cctagcaata gttctgagcc tacagcaata atggcaattg acatttatat cccccttgta
     2521 tcgtttaatt cttttttcat gtattccatt taaaaattca catcaatttt agattcaatg
     2581 tatcagatgc tac
//
LOCUS       DAPDIM010000131         2544 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000131 DAPDIM010000000
VERSION     DAPDIM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2544
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.137"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(91..174)
                     /locus_tag="RFE25_002770"
     tRNA            complement(91..174)
                     /locus_tag="RFE25_002770"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(138..140),aa:Leu,seq:caa)
     gene            complement(213..287)
                     /locus_tag="RFE25_002771"
     tRNA            complement(213..287)
                     /locus_tag="RFE25_002771"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(252..254),aa:Gly,seq:tcc)
     gene            complement(391..465)
                     /locus_tag="RFE25_002772"
     tRNA            complement(391..465)
                     /locus_tag="RFE25_002772"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(430..432),aa:Gly,seq:tcc)
     gene            complement(473..546)
                     /locus_tag="RFE25_002773"
     tRNA            complement(473..546)
                     /locus_tag="RFE25_002773"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(512..514),aa:Cys,seq:gca)
     gene            complement(552..623)
                     /locus_tag="RFE25_002774"
     tRNA            complement(552..623)
                     /locus_tag="RFE25_002774"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(589..591),aa:Gln,seq:ttg)
     gene            complement(635..707)
                     /locus_tag="RFE25_002775"
     tRNA            complement(635..707)
                     /locus_tag="RFE25_002775"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(672..674),aa:His,seq:gtg)
     gene            complement(710..783)
                     /locus_tag="RFE25_002776"
     tRNA            complement(710..783)
                     /locus_tag="RFE25_002776"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(749..751),aa:Trp,seq:cca)
     gene            complement(799..879)
                     /locus_tag="RFE25_002777"
     tRNA            complement(799..879)
                     /locus_tag="RFE25_002777"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(843..845),aa:Tyr,seq:gta)
     gene            complement(885..960)
                     /locus_tag="RFE25_002778"
     tRNA            complement(885..960)
                     /locus_tag="RFE25_002778"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(925..927),aa:Thr,seq:tgt)
     gene            complement(968..1040)
                     /locus_tag="RFE25_002779"
     tRNA            complement(968..1040)
                     /locus_tag="RFE25_002779"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1005..1007),aa:Phe,seq:gaa)
     gene            complement(1059..1134)
                     /locus_tag="RFE25_002780"
     tRNA            complement(1059..1134)
                     /locus_tag="RFE25_002780"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1099..1101),aa:Asp,seq:gtc)
     gene            complement(1156..1229)
                     /locus_tag="RFE25_002781"
     tRNA            complement(1156..1229)
                     /locus_tag="RFE25_002781"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1193..1195),aa:Met,seq:cat)
     gene            complement(1244..1336)
                     /locus_tag="RFE25_002782"
     tRNA            complement(1244..1336)
                     /locus_tag="RFE25_002782"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1298..1300),aa:Ser,seq:tga)
     gene            complement(1375..1450)
                     /locus_tag="RFE25_002783"
     tRNA            complement(1375..1450)
                     /locus_tag="RFE25_002783"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1415..1417),aa:Asp,seq:gtc)
     gene            complement(1461..1550)
                     /locus_tag="RFE25_002784"
     tRNA            complement(1461..1550)
                     /locus_tag="RFE25_002784"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1512..1514),aa:Ser,seq:tga)
     gene            complement(1560..1633)
                     /locus_tag="RFE25_002785"
     tRNA            complement(1560..1633)
                     /locus_tag="RFE25_002785"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1597..1599),aa:Ile,seq:cat)
     gene            complement(1662..1735)
                     /locus_tag="RFE25_002786"
     tRNA            complement(1662..1735)
                     /locus_tag="RFE25_002786"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1699..1701),aa:Met,seq:cat)
     gene            complement(1757..1832)
                     /locus_tag="RFE25_002787"
     tRNA            complement(1757..1832)
                     /locus_tag="RFE25_002787"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1797..1799),aa:Ala,seq:tgc)
     gene            complement(1850..1923)
                     /locus_tag="RFE25_002788"
     tRNA            complement(1850..1923)
                     /locus_tag="RFE25_002788"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1887..1889),aa:Pro,seq:tgg)
     gene            complement(1933..2006)
                     /locus_tag="RFE25_002789"
     tRNA            complement(1933..2006)
                     /locus_tag="RFE25_002789"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1970..1972),aa:Arg,seq:acg)
     gene            complement(2025..2113)
                     /locus_tag="RFE25_002790"
     tRNA            complement(2025..2113)
                     /locus_tag="RFE25_002790"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2077..2079),aa:Leu,seq:taa)
     gene            complement(2124..2198)
                     /locus_tag="RFE25_002791"
     tRNA            complement(2124..2198)
                     /locus_tag="RFE25_002791"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2164..2166),aa:Gly,seq:gcc)
     gene            complement(2202..2283)
                     /locus_tag="RFE25_002792"
     tRNA            complement(2202..2283)
                     /locus_tag="RFE25_002792"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2247..2249),aa:Leu,seq:tag)
     gene            complement(2287..2362)
                     /locus_tag="RFE25_002793"
     tRNA            complement(2287..2362)
                     /locus_tag="RFE25_002793"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2327..2329),aa:Lys,seq:ttt)
     gene            complement(2368..2443)
                     /locus_tag="RFE25_002794"
     tRNA            complement(2368..2443)
                     /locus_tag="RFE25_002794"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2408..2410),aa:Thr,seq:tgt)
     gene            complement(2460..2535)
                     /locus_tag="RFE25_002795"
     tRNA            complement(2460..2535)
                     /locus_tag="RFE25_002795"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2500..2502),aa:Val,seq:tac)
BASE COUNT          709 a          649 c          599 g          587 t
ORIGIN      
        1 cttttatttg tattgtatag agagaaataa aaagaaacct tgttttacaa ggtttctaat
       61 acgttatgtt atgtaaataa cagttaatta taccggtggt cggggtcgaa ccgacactcc
      121 acaagtggaa cgggattttg agtcccgcgc gtctgccaat tccgccacac cggcttaatg
      181 gtaaacaaaa aacttccctt tggaagcaat tatggagcgg aagataggat ttacacctat
      241 acctcgttcc gggaaggaac gtgttctaaa agttgaacta ctcccgcaaa tattaaatta
      301 tggagcggaa gataggattt acacctatac ctcattccag gaaggaatgt attctaagag
      361 ttgaaatact cccgcattat tattaaatta tggagcggaa gataggattt gcacctatac
      421 ctcgttccgg gaaggaacgt gttctaaaag ttgaactact cccgcataaa cctggaggcg
      481 gcaaccggat ttgaaccggt gataaaggtt ttgcagacct ctgccttacc acttggctat
      541 gccgccaata actgggctag ctggattcga accaacgagt gacggagtca aagtccgttg
      601 ccttaccgct tggctatagc ccattaataa taagggcggc tgaaggggat cgaaccctcg
      661 aatgtcggaa ccacaatccg atgtgttaac cacttcacca cagccgccat ggcaggggca
      721 gtaggaatcg aacccacacc aaaggttttg gagacctcta ttctaccgtt gaactatgcc
      781 cctattaaaa ataataaatg gaggggggca gattcgaact gccgaacccg aaggagcgga
      841 tttacagtcc gccgcgttta gccacttcgc tacccctcca taaatggtgc cggccagagg
      901 acttgaaccc ccaacctact gattacaagt cagttgctct accaattgag ctaggccggc
      961 taagaaatgg ttcaggacag agtcgaactg ccgacacatg gagcttcaat ccattgctct
     1021 accaactgag ctactgaacc ataataaaaa tgtaatgatg gcggtctcga cgggaatcga
     1081 acccgcgatc tcctgcgtga caggcaggcg tgttaaccgc tacactacga gacctattaa
     1141 attaaaaact atgtattgcg ggaggcggat ttgaaccacc gaccttcggg ttatgagccc
     1201 gacgagctac cgaactgctc catcccgcga taataaaaaa taatggcgga ggaagaggga
     1261 ttcgaacccc cgcggcccgt taaggccctg tcggttttca agaccgatcc cttcagccgg
     1321 acttgggtat tcctccatta ttataggtaa atcgctatta attataaaat taaatggcgg
     1381 tctcgacggg aatcgaaccc gcgatctcct gcgtgacagg caggcgtgtt aaccgctaca
     1441 ctacgagacc attagtaaaa cggaggaaga gggattcgaa cccccgcgag ccgttaagcc
     1501 cctgtcggtt ttcaagaccg atcccttcag ccggacttgg gtattcctcc aaaattatat
     1561 ggaccttgca ggactcgaac ctgcgaccga acggttatga gccgttagct ctaaccaact
     1621 gagctaaagg tcctaaatat aattttacaa ctaataaata gtggcggtgg aggggatcga
     1681 acccccgacc tcacgggtat gaaccgtacg ctctagccag ctgagctaca ccgccttata
     1741 tagtttgtaa ataatatggt ggagactagc gggatcgaac cgctgacctc ctgcgtgcaa
     1801 agcaggcgct ctcccagctg agctaagccc ccataataat tacagtatat cgggaagaca
     1861 ggattcgaac ctgcgacccc ttggtcccaa accaagtgct ctaccaagct gagctacttc
     1921 ccgtataatt aacgcgcccg ataggagtcg aacccataac ctcttgatcc gtagtcaaac
     1981 gctctatcca attgagctac gggcgcatat gtttttattg aaaatggtgc cgaggaccgg
     2041 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
     2101 ccgccacccc ggcactataa aaatggagca gaagacggga ttcgaacccg cgaccccaac
     2161 cttggcaagg ttgtattcta ccgctgaact acttctgcat atgcgggtga agggagtcga
     2221 acccccacgc cgtaaggcgc tagatcctaa gtctagtgcg tctgccaatt ccgccacacc
     2281 cgcaaatggt gagccataga ggattcgaac ctctgaccct ctgattaaaa gtcagatgct
     2341 ctaccaactg agctaatggc tcttccatgg tgccggccag aggacttgaa cccccaacct
     2401 actgattaca agtcagttgc tctaccaatt gagctaggcc ggcaatatgt aagaataaat
     2461 ggtggagaat gacgggttcg aaccgccgac cctctgcttg taaggcagat gctctcccag
     2521 ctgagctaat tctccgattt aaaa
//
LOCUS       DAPDIM010000132         2451 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000132 DAPDIM010000000
VERSION     DAPDIM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2451
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.139"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            234..1457
                     /locus_tag="RFE25_002796"
     CDS             234..1457
                     /locus_tag="RFE25_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HDU2817781.1"
                     /translation="MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKS
                     EILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRG
                     TTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
                     LIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSE
                     LKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLE
                     FNVRPVLEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVAS
                     SYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKY
                     IDIFKEASIQYLKEK"
     gene            1901..>2451
                     /locus_tag="RFE25_002797"
     CDS             1901..>2451
                     /locus_tag="RFE25_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDU2817782.1"
                     /translation="MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFI
                     ASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNR
                     FLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTS
                     VSAFNNAGFALFKNNLIDYSSDP"
BASE COUNT          840 a          371 c          411 g          829 t
ORIGIN      
        1 atttgaaatt tatatataat tattagctaa ataatatcct gcatctttct catacaattt
       61 actataaaat taagcatacc cgatatcagt gttaataaga tcgttgatac tagacagtta
      121 atttcataga acgaaatcaa ataacacgct actttctgca ttttaaatta tgtttaagaa
      181 taaaaattat gtttatataa atatatatac tactttgaaa aggtgtgagc ttaatgacaa
      241 cttttagtga aaaagaaaaa attcaattac tagcagatat tgttgaacta caaactgaaa
      301 ataataatga aatagacgtt tgtaattatt taaaagattt attcgacaag tacgatatta
      361 aatctgaaat tttgaaagtt aatgaacacc gcgccaatat cgttgcagaa atcggtaacg
      421 gctcacctat actcgcattg agtggtcata tggatgttgt tgatgcagga aatcaagata
      481 attggactta tccccctttt caactcacag aaaaagctgg caaattatac ggtcgaggca
      541 caacggatat gaaaggcggt ctgatggctt tggtcatcac actcattgaa ttaaaagaac
      601 aaaatcaatt gcctcaagga acgataagat tactagctac tgctggcgaa gagaaagaac
      661 aagaaggtgc caaattattg gctgataaag gctatttaga cgatgtagat ggcttaatta
      721 ttgctgaacc aactggatct ggaatttatt atgcacataa agggtctatg tcatgtaaag
      781 taactgcaac tggcaaagct gtccatagct cagttccatt tattggtgac aatgcaattg
      841 atacactgct tgaattttat aatcaattta aagaaaaata ttcagagctt aaaaaacatg
      901 atactaaaca tgaattagat gttgcaccca tgttcaaatc attgatagga aaagaaattt
      961 ctgaagagga tgcaaattat gcatctggtc ttacagctgt atgttcgatt ataaatggcg
     1021 gcaaacaatt taactctgta ccagatgaag cttcacttga atttaacgta agaccagttc
     1081 ttgagtatga taacgacttt atagaatcgt ttttccaaaa tatcattaat gatgtggata
     1141 gcaataagct ttcactcgat attccaagca atcaccgacc tgtaacaagc gataaaaata
     1201 gcaaattaat tactacgatt aaagatgtag cttctagtta tgtagaacaa gacgaaatat
     1261 ttgtttcagc gcttgtaggt gcaacagatg cctctagttt cttaggagat aataaggaca
     1321 atgttgattt agccattttt ggaccaggta atccattaat ggcacatcaa atcgatgaat
     1381 atattgaaaa agatatgtac ctgaaatata ttgatatttt taaagaggct tccattcaat
     1441 atttaaaaga gaaataagaa cgatgctgtc agctgcccta ttcgcgtgct ggcagttttt
     1501 tattgcgaat tttaagttga tagaaatagc gatgaatatt gtttgactgt aaatattcaa
     1561 atatcaacaa gcacattttc attgattaag tgatgtaaaa ctgaaattat ggtggtgatt
     1621 tgtcatacat atattgcatt gtctattgaa attgggaatc caatttctct ttgttgaggc
     1681 ccccacccca acttacattg tttgtagaat ttcttttcga aattctctgt gttggggccc
     1741 ccaccccaac ttgcattgtc tgttgaaatt gggaatccaa tttctctgtg ttggggcccc
     1801 tgactagaat tgaaaagtaa tacacatcag taacatttct attttcattt atgatattat
     1861 ctaattatta atttataata taaaggagta tgcaattaaa atgaacaaag tccacaaacc
     1921 tttatatttt tatttaatgc ttttcttctc tacaactatc ataggtgctc ttttattata
     1981 tttacctttc actggtaaaa agccaatatc ttttttagat gccctattta tagcttcaag
     2041 tgcatttaca gttactggcc tatccccagt tgatatagga tcacagttta atatacttgg
     2101 tgaaatagta atactattat taattcaaat aggtggtctg ggtatcgtga ccgtaaccct
     2161 attgacacta gtatttttaa atagaaagat atcaatgaaa aatagattct tgattatggt
     2221 tacatggaat attgacgaac ctggtggtgt tattaagcta attaaacact tggctattta
     2281 tagtttagtc actgaattaa ttggtatgat ttgtttgtgt ttatctttta taccaaaatt
     2341 tggtataggc aaaggtttat ttttaagctt attcacatca gtatcagctt ttaataatgc
     2401 tggatttgcc ctttttaaga ataacttaat agattattct agtgatccaa t
//
LOCUS       DAPDIM010000133         2418 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000133 DAPDIM010000000
VERSION     DAPDIM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2418
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.140"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(523..1167)
                     /locus_tag="RFE25_002798"
     CDS             complement(523..1167)
                     /locus_tag="RFE25_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDU2817783.1"
                     /translation="MSQNTNHSYYHQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLP
                     LSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDI
                     FYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTI
                     ITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR"
     gene            1528..2325
                     /locus_tag="RFE25_002799"
     CDS             1528..2325
                     /locus_tag="RFE25_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDU2817784.1"
                     /translation="MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKY
                     NTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNII
                     ASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNL
                     YTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGP
                     YGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH"
BASE COUNT          896 a          388 c          316 g          818 t
ORIGIN      
        1 tgtagtcagt ttaattaaac tatccaattg aaaacacact actttttagt attttcaaaa
       61 taattttaaa tgaccacatc tacaacgtat tactattatc ttttgttagt tatatattca
      121 ttttcaattt aaaaataaac acttatttaa atcacattct acttttgaga tgagctcaaa
      181 ctaacattaa attgtttata ttatctatac ttcttcctat taatatttcg attttaaaat
      241 taatacgtag ctatacttta cttttctaat aaaagtgtaa ttagaaaggc aagtacacct
      301 gtttaaagtt tatcttctaa gatttgttta ctttagaact atagcagtta atcattttaa
      361 tgattaataa tatctttaca attaaggtaa taaattttta ttgctttatc agtaaaatct
      421 ctatctaaat ttctaattta tgacaatcgc tccaatttaa ggttgatatt cattattgat
      481 tattccaaaa ctttatacaa atttctttat taatttaact gtttatcttc tgaacatatt
      541 agcaaggtaa agtatatcct taataatatt caacaaatta ataaatagat taaatcccat
      601 ttctcttggt gaatagtcac ctctttttaa acgattaaaa tcatacaaag tataaagtag
      661 aaataacaac agactaacga cggtaataat agtgtaaaaa ataggatttt gaagaaaaat
      721 accaattaga ctcgcaataa ttaatgttat taatgtaacg aataaatatt tgcctatact
      781 cgatgcatct ccaacgaaga aataaccaat aataccaaat gctataaatg caaaaattgc
      841 taatgcgata tttttataga aaatatctgg tcctaaattt tgtaaatacg tggtaaacgt
      901 tgcgtatgac aataagccaa tcactacagc gtaaatatgt gaaataatta aaccgaaccg
      961 tctcgctctt tcaaaaacaa gtgttgctaa aataataatc agtaatccaa atgacaaggg
     1021 ttgtcgccaa cttaatggta aaaactgacc tagatagcat cctatgccaa atataatcca
     1081 ataatacata aaataaagcc acactttact tattgattga gcatgctggt tttgatgata
     1141 atatgaatga tttgtatttt gcgacaaaat aattcctcct tctaccgtcg ttttatgcgt
     1201 caaattttac agtaaatttt gcttcatcaa aagaaataac ctttaacaag tatagtaatt
     1261 ttacatttta caatgttaca aaatataatt ttttataatt agttaaaatc actaaaacgc
     1321 ttttatacac tatcaaatca gcatttataa aaatatgaac cgatatccta aaatgttaat
     1381 aatattacaa gataataaca aaccacacaa agctacttat ttttgataat atggaaatcg
     1441 taatataaaa cgaaaactta atttactata taaattgtct taataatttt taaaagtagt
     1501 aaaacttaat tttaaggagg agtccctttg aaaaaattag catttgcaat aacagcaaca
     1561 tctggtgcag ctgcattttt aacgcatcat gatgcacaag cttctacaca acatacagta
     1621 caatctggtg aatcattatg gagtattgct caaaaataca acacttcagt agagagtatt
     1681 aaacaaaata accaattaga taacaacttg gtattccctg gtcaagttat ctcagtaggt
     1741 ggaagtgatg cacaaaatac gtcaaacact tctccacaag ctggttcagc atcatctcat
     1801 actgtacaag ctggtgaatc attaaatatc attgctagca gatatggtgt ttcagttgat
     1861 caattaatgg cagccaataa cttacgtggt tatttaatta tgcctaacca aacattacaa
     1921 attcctaatg gtggatcagg tggtacaaca ccaacagcta caacaggtag caatggcaat
     1981 gcatcatctt ttaatcacca aaatttatac actgctggtc aatgtacatg gtacgtattt
     2041 gaccgtcgtg ctcaagctgg tagtccaatt agcacatatt ggtcagacgc taagtattgg
     2101 gctggtaacg cagctaatga tggttaccaa gtaaacaaca caccatcagt tggttcaatt
     2161 atgcaaagca cacctggtcc atatggtcat gttgcttatg ttgaacgtgt caatggtgat
     2221 ggtagtatct tgatttctga aatgaattac acatatggtc catacaatat gaactaccgt
     2281 acaattccag cttcagaagt ttctagctat gcattcatcc attaattaaa taaattgtac
     2341 tgatatatac tagcaattca catcatgtga gattgctagt tttttatttt tgaaaaaaat
     2401 tttcattttg gtacaaaa
//
LOCUS       DAPDIM010000134         2208 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000134 DAPDIM010000000
VERSION     DAPDIM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2208
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.141"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            367..522
                     /locus_tag="RFE25_002800"
     CDS             367..522
                     /locus_tag="RFE25_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817785.1"
                     /translation="MMVKKLLKAIKQNFLYEQSNITFKMIVFGYKRLSKMLFQFEINH
                     INFLWEG"
     gene            530..1051
                     /locus_tag="RFE25_002801"
     CDS             530..1051
                     /locus_tag="RFE25_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817786.1"
                     /translation="MINIISAIGSIGTFIMALFYFVSVSVQLYQMKISFLPALGFNQI
                     LLEREKDQLNIMNSATEEHHHKDYIKLYNLGGGAAKKIAIEVLLGNDKVIQKKYVNIL
                     PSKEGYMLPINKNVYEELERTIENNGYEADLNVRMTYYHNVSRKQQEVILKGQIDRFN
                     TYNNKEIYDLQFI"
     gene            1190..1720
                     /locus_tag="RFE25_002802"
     CDS             1190..1720
                     /locus_tag="RFE25_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDU2817787.1"
                     /translation="MQIRQIHQHDFAQVDQLIRTAFENSEHGYGNESELVDQIRLSDT
                     YDNNLEIVAVLQNEVVGHGLLSEVYLDNGAQREIGLVLAPVSVDIHHQNKGIGKRLIQ
                     ALEREAILKGYNFISVLGWPTYYANLGYQRASMYDIYPPYDGIPDEAFLIKELKVNSL
                     AGKTGTINYTSAFEKI"
     gene            1983..>2208
                     /locus_tag="RFE25_002803"
     CDS             1983..>2208
                     /locus_tag="RFE25_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HDU2817788.1"
                     /translation="MNMKKKEKHAIRKKSIGVASVLVGTLIGFGLLSSKEADASENSV
                     TQSDSASNESKSNDSSSVSAAPKTDDTNVSD"
BASE COUNT          853 a          236 c          392 g          727 t
ORIGIN      
        1 ttaaacaaag ttgatatttt gtgagattct aagatgatat taaataattc ttgtaataat
       61 gatcctatgt attgttgcaa taaattaatg aaactataat tactaatatt atattacttt
      121 tattgataga aatatattac ttttttaaaa aacttgtaat atatcgaaag atttaaatgt
      181 aaaattttga tttgttaaga aattacgttt gtaaaaataa aaaaatcaac ttatttgtat
      241 gagatgaata tgtattgaag aagatgtgtt attaatttgg aaaatactgg tcaaagatgg
      301 gagctcttaa aagcgttatt gtatttttta gtcaatgcaa atagattgcc gtaataataa
      361 tcgtacttga tggttaaaaa attacttaag gctataaagc aaaacttttt atatgagcag
      421 tcgaatataa cgtttaaaat gattgttttt ggatataaac gattaagtaa aatgcttttt
      481 cagtttgaaa ttaatcatat aaatttctta tgggaaggtt gatatcttaa tgattaatat
      541 catttcagct ataggatcta ttggaacatt tattatggct ttattttatt ttgtatcagt
      601 ttcagttcaa ctttatcaaa tgaaaattag ctttctgcca gctttaggtt ttaaccaaat
      661 tttattagaa agggagaagg atcaacttaa tataatgaat tcggcaacag aagagcatca
      721 tcataaagat tatattaaac tatataattt aggtggcggt gctgctaaaa aaattgcaat
      781 agaggtttta ttgggtaatg ataaagtcat tcagaaaaaa tacgtgaata ttttacctag
      841 taaagaaggg tacatgttac caattaataa aaatgtgtac gaagaattag aaagaacgat
      901 tgagaataat ggttatgaag ctgatttgaa tgtacgtatg acttattatc ataatgtaag
      961 tcgcaaacaa caggaagtta tattaaaagg tcaaatcgac cgttttaata cttataataa
     1021 taaagaaatt tatgatttgc agtttatcta aaaattgatt taagagggta gttgtttatt
     1081 gcgaaaaata tcattcaatt ttaatgaaat aatggcgtca ttactataaa atattacttt
     1141 atgttgtaat gcatttttct ataagataga actaaaagga ggggcaaaga tgcaaattag
     1201 acaaatacat caacatgact ttgctcaagt tgaccagtta attagaacgg catttgaaaa
     1261 tagtgaacat ggttatggta atgaatcaga gctagtagac caaattcgtc taagtgatac
     1321 gtatgacaat aacttagaaa tagtagctgt tcttcaaaac gaagttgtag ggcacggttt
     1381 actaagtgaa gtttatcttg ataacggagc acaacgggaa attggattag tgttagcacc
     1441 tgtatctgtt gatattcatc atcaaaataa aggtattggg aagcgattga ttcaagcatt
     1501 agaacgagaa gcaatattaa aaggatataa ttttatcagt gtattaggat ggccgacgta
     1561 ttatgccaat ctaggatatc aacgcgcaag tatgtacgac atttatccac catatgatgg
     1621 tataccagac gaagcgtttt taattaaaga attaaaagtg aacagtttag cgggaaaaac
     1681 aggtaccata aattacacat ctgcttttga aaaaatatga tttaaagcta ggattacatt
     1741 aggtagagtt catattaata ataaaaaatg tttgcaatca aatcgtacgt tgtcgtttgt
     1801 aattcttaaa atagcaataa ataaaatgtt tgttagtaaa gtattattgt ggataataaa
     1861 atatcgatac aaattaattg ctataatgca attttagtgt ataattccat taacagagat
     1921 taaatatatc tttaaagggt atatagttaa tataaaatga ctttttaaaa agagggaata
     1981 aaatgaatat gaagaaaaaa gaaaaacacg caattcggaa aaaatcgatt ggcgtggctt
     2041 cagtgcttgt aggtacgtta atcggttttg gactactcag cagtaaagaa gcagatgcaa
     2101 gtgaaaatag tgttacgcaa tctgatagcg caagtaacga aagcaaaagt aatgattcaa
     2161 gtagcgttag tgctgcacct aaaacagacg acacaaacgt gagtgata
//
LOCUS       DAPDIM010000135         2129 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000135 DAPDIM010000000
VERSION     DAPDIM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2129
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.142"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..1407
                     /locus_tag="RFE25_002804"
     CDS             <1..1407
                     /locus_tag="RFE25_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDU2817789.1"
                     /translation="PKDDSDDKEKNNKKVPIWKDVKTIKYTISSQEVNYPEYIYHFIV
                     EGNRRLEKPKGIMIRNAQTMSSVENLYNSRKKYKQDVEYPHFYVDRHNIWAPRRAVFE
                     VPNEPDYIVIDVCEDYSASKNEFIFNEIHAMVVAVDMMAKYEIPLSIENLKVDDSIWR
                     SMLEHVNWNMIDNGVAPKDKYEALEKALLNIFKNREKLLNSITKPTVTKSRIKVMVDN
                     KNADIANVRDSSPTANNGSASKQPQIITETSPYTFKQALDKQMARGNPKKSNAWGWAN
                     ATRAQTSSAMNVKRIWESNTQCYQMLNLGKYQGVSVSALNKILKGKGTLNNQGKAFAE
                     ACKKHSINEIYLIAHAFLESGYGTSNFANGKDGVYNYFGIGAYDNNPNYAMTFARNKG
                     WTSPAKAIMGGASFVRKDYINKGQNTLYRIRWNPKNPAMHQYATAIEWCQHQASTIAK
                     LYKQIGLKGIYFIRDKYK"
     gene            1420..>2129
                     /locus_tag="RFE25_002805"
     CDS             1420..>2129
                     /locus_tag="RFE25_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HDU2817790.1"
                     /translation="MYKIKDVETRIKNDGVDLGDIGCRFYTEDENTASIRIGINDKQG
                     RIDLKAHGLTPRLHLFMEDGSIFKNEPLIIDDVVKGFLTYKIPKKVIKHAGYVRCKLF
                     LEKEEQKIHVANFSFNIIDSGIESAVAKEIDVKLVDDAITRILKDNATDLLSKDFKEK
                     IDKDVISYIEKNESRFKGAKGDKGEPGQPGAKGEAGKKGEQGVPGKNGTVVSINPDTK
                     MWQIDGKDTNIKAEPELL"
BASE COUNT          837 a          316 c          429 g          547 t
ORIGIN      
        1 ccgaaagatg atagtgatga taaggaaaag aataataaaa aagttccgat ttggaaagac
       61 gtaaaaacta taaagtacac tatttctagc caagaggtta attatccgga atatatttat
      121 cactttatag tagagggtaa tcgacgactc gaaaaaccta aagggataat gattagaaat
      181 gctcaaacaa tgagttcagt agaaaattta tataacagta ggaagaaata caaacaagat
      241 gtggaatatc cccactttta tgttgataga cataatattt gggcacctag aagagctgta
      301 tttgaagttc ctaatgaacc tgattatata gttatagacg tatgtgaaga ttatagtgcg
      361 agtaaaaatg aatttatttt taatgagatt cacgcaatgg ttgtagctgt agatatgatg
      421 gccaaatatg agatacctct aagtattgaa aatttaaaag tagacgacag catttggcgt
      481 tctatgttgg aacatgttaa ttggaatatg attgacaacg gtgttgcccc taaagataaa
      541 tacgaagcat tagaaaaggc attacttaat atatttaaaa acagagaaaa attattaaat
      601 tctataacta aaccaacagt aacaaaatct agaataaaag ttatggtaga taataaaaac
      661 gctgatatag ctaatgtaag agactcgtca ccaacagcca acaatggttc ggcatctaaa
      721 caaccgcaga tcataacaga aacgagtcct tatacattca aacaagcact ggataaacaa
      781 atggcaagag gtaacccgaa aaaatctaat gcttggggtt gggctaacgc tacacgagca
      841 caaacaagtt cagcaatgaa tgttaaacga atatgggaaa gtaacacgca gtgctaccaa
      901 atgcttaatt taggcaagta tcaaggtgtt tcagttagcg cacttaataa gatacttaaa
      961 ggtaagggaa cattgaataa tcaaggtaaa gcgttcgcag aagcttgtaa aaagcacagc
     1021 attaatgaaa tttatttaat cgcgcacgct ttcttagaaa gtggatatgg aacaagtaac
     1081 ttcgctaacg gaaaagatgg agtatacaac tacttcggca ttggcgctta cgacaacaat
     1141 cctaactacg caatgacgtt tgcaaggaat aaaggttgga catctccagc aaaagcaatc
     1201 atgggcggtg ctagcttcgt aagaaaggat tacatcaaca aaggacagaa tacactgtac
     1261 agaatcagat ggaatcctaa gaatccagct atgcaccaat acgctactgc tatagagtgg
     1321 tgccaacatc aagctagtac aatcgctaag ctatataaac aaatcggctt aaaaggtatc
     1381 tattttataa gagataaata taaataaaga ggtgtataaa tgtacaaaat aaaagatgtt
     1441 gaaacgagaa taaaaaatga tggtgttgac ttaggtgaca ttggctgtcg attttacact
     1501 gaagatgaaa atacagcatc tataagaata ggtatcaatg acaaacaagg tcgtatcgat
     1561 ctaaaagcgc atggcttaac acctagattg catttgttta tggaagatgg ctctatattc
     1621 aaaaatgagc cccttattat cgacgatgtt gtaaaagggt tccttaccta caagatacct
     1681 aaaaaggtta tcaaacacgc tggttatgta cgttgtaagc tgtttttaga gaaagaagaa
     1741 caaaaaatac atgtcgcgaa cttttctttc aatatcattg atagtggtat tgaatctgct
     1801 gtagcaaaag aaatcgatgt taaattggta gatgatgcta ttacgagaat tttaaaagat
     1861 aacgcgacag atttattgag caaagacttt aaagagaaaa tagataaaga tgtcatttct
     1921 tacatcgaaa agaatgaaag tagatttaaa ggtgcgaaag gtgataaagg cgaaccggga
     1981 caacctggtg caaaaggtga agcaggtaaa aaaggagaac aaggcgtacc cggtaaaaac
     2041 ggtactgtag tatcaatcaa tcctgacact aaaatgtggc aaattgatgg taaagataca
     2101 aatatcaaag cagaacctga gttattgga
//
LOCUS       DAPDIM010000136         2121 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000136 DAPDIM010000000
VERSION     DAPDIM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2121
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.143"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(59..1996)
                     /gene="isdB"
                     /locus_tag="RFE25_002806"
     CDS             complement(59..1996)
                     /gene="isdB"
                     /locus_tag="RFE25_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme uptake protein IsdB"
                     /protein_id="HDU2817791.1"
                     /translation="MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAQAAAEE
                     TGGTNTEAQPKTEAVASPTTTSEKAPETKPVANAVSVSNKEVEAPTSETKEAKEVKEV
                     KAPKETKAVKPAAKATNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKENG
                     EQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVK
                     DYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAE
                     KLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQN
                     VQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYW
                     KDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVD
                     KEAFTKANTDKSNKKEQQDNSAKKEATPATPSKPTPSPVEKESQKQDSQKDDNKQLPS
                     VEKENDASSESGKDKTPATKPTKGEVESSSTTPTKVVSTTQNVAKPTTASSKTTKDVV
                     QTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLPQTGEESNKDMTLP
                     LMALLALSSIVAFVLPRKRKN"
BASE COUNT          528 a          329 c          347 g          917 t
ORIGIN      
        1 atacctcatc cgccaattaa aatttgttaa tttaataatt aaatataaag acgatttatt
       61 agtttttacg ttttctaggt aatacgaatg caacgatgct acttaaagct agtaatgcca
      121 ttaatggtaa tgtcatatct ttatttgatt cttcaccagt ttgtggtaat gattttgctt
      181 tattttcttg tgtattttta ttgttttggc tttgagtgtg tccatcattt gtgtttttaa
      241 tgtttgcttt ttgtaatgga gcactatctt ttgcttcgct agaacctgct gaagtttgaa
      301 caacatcttt tgttgttttt gatgaagcag ttgttggttt tgcaacattt tgagtcgtag
      361 atactacctt agttggagtt gtactacttg attctacttc acctttagtt ggttttgtag
      421 caggcgtttt gtctttacct gactcactag atgcgtcatt ttctttttca acacttggta
      481 attgtttatt gtcatctttt tggctgtctt gtttttgtga ttctttttca acaggtgatg
      541 gtgttggttt gctaggcgta gctggagtag cttccttctt agctgagtta tcttgttgtt
      601 cttttttgtt agatttatcg gtattggctt ttgtaaatgc ttctttatca acgattctga
      661 catggtattg tccatcataa tcaatcgttt ttacgtgaac tttaacgata gcatcatata
      721 gagttttacc ttcaacatat gggaaaataa ttgttctagt attattttta gcatctttgc
      781 ttatagttct aacacgttga ccttcaacca tgaaatcttt ccagtaatcg tcattagtag
      841 tttccatgac catatatttt ttgccgttaa gcatacctgt tttaataggg tgtttaacaa
      901 aagtatccat catagattcg ttattctcaa cactttcata aacaacatat tttgtatctt
      961 gtaaatcagt cattttttca tttgttggtt gtacattttg gaattcagta atagctgatt
     1021 tcacttgctc atctaaagct ttctttgtat cctctaattt cttcttgtac tcagccttta
     1081 atttttcagg aagtttatct tgaattttat ttaattcata aacttgtctt tctagtgttt
     1141 tcgctttttt atatggcgct aataattttt cagctttata atcttcttca gttttgaatt
     1201 tatctgcact gttataaatt ggttgtgcga attccattaa tgtgtaatcg tatttttctt
     1261 ctttgttatt gaagtgagtt gaacttacaa ttttaacggc ttttgttcca tttgaaacag
     1321 agaagcgaat gtaagcgtaa tctttaacag tatcgtatga tactaattta attggcaact
     1381 ttttgtcacc ttcataaact tcaaattttc tccaaaattg acctgattgt aatcctaatt
     1441 caatttctgg ttttgaatca gtgaaaataa ctctagcagg tttaacagag ctggcataat
     1501 gataaaattg ttgctcacca ttttcttttt tcatttcaaa atcaattgga cgagagtttg
     1561 gtgcgctatg atctttatct tttattgcag ggtttttaat cgcttctcta agttcctgat
     1621 tcaaaatagg atatgtattg ttagtggctt ttgctgctgg tttaactgct tttgtttcct
     1681 taggggcttt aacttcttta acttctttag cttcttttgt ttcagaagta ggggcctcaa
     1741 cttctttatt agatactgag acagcattag ctactggttt agtttctgga gctttttcag
     1801 atgttgttgt tggacttgca actgcttcag tttttggttg tgcttctgta tttgtaccac
     1861 ctgtttcttc agctgctgct tgtgcttcgc catttgacat taataataaa agtgtactaa
     1921 tcgctacaga tgcaacgcct agtgatgact ttctaattga ataaaatgat ttaaattctt
     1981 tttgctgttt gttcatgttg tagaaacaac tcctaattgt atattatcaa ctgataatca
     2041 ttatcaattg attacttgta ttgtacattg aaatggtagt taattgcaac attattttat
     2101 aaaaaaataa cctatgttat a
//
LOCUS       DAPDIM010000137         2086 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000137 DAPDIM010000000
VERSION     DAPDIM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2086
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.144"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            151..513
                     /locus_tag="RFE25_002807"
     CDS             151..513
                     /locus_tag="RFE25_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YojF family protein"
                     /protein_id="HDU2817792.1"
                     /translation="MLEPIKEQEVIDLLASFEHKPVYLHVETTNGAYANHFDQRVFNA
                     GTFLRNIQVTYTHAQLKGGNKEPYRIGLKLSNGGWVYVQGLTHFEVNEHDEFLIAGFN
                     YEGQLAAALQISERPFNL"
     gene            527..1192
                     /gene="bshB2"
                     /locus_tag="RFE25_002808"
     CDS             527..1192
                     /gene="bshB2"
                     /locus_tag="RFE25_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol biosynthesis deacetylase BshB2"
                     /protein_id="HDU2817793.1"
                     /translation="MTDERHVLVIFPHPDDETFSSAGTLASYIQKGIPVTYACLTLGQ
                     MGRNLGNPPFATRESLPSIRERELEEACKVIGITDLRKMGLRDKTVEFEPYEHIDGMI
                     KSLIDDTNPSLIISFYPGYAVHPDHEATADAVIRTVERMPKEERPRLTLVAFSNDATE
                     ALGEPDIQNDITDFKELKIKAFEAHASQTGPFLKQLASPEIDGKQHSFLTVEPYWTYH
                     FKS"
     gene            1205..2083
                     /locus_tag="RFE25_002809"
     CDS             1205..2083
                     /locus_tag="RFE25_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002445753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE2"
                     /protein_id="HDU2817794.1"
                     /translation="MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFL
                     FEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIEL
                     EFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDK
                     VTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAM
                     EANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNE
                     ESIHQHDAFAKLKYRK"
BASE COUNT          744 a          341 c          384 g          617 t
ORIGIN      
        1 agtaaaaaac taatgctgta tgattacgta atcctgagta attacccttc atgaaaatta
       61 atttataaat aattgagcaa tcgtatacaa ttatcgaata gtttttagta aaatagaaag
      121 ataaacacat tgatagtgta aggagtgaac gtgttggaac caattaaaga acaagaagtt
      181 atagatttac ttgcttcttt tgaacataaa cctgtgtatc tgcatgttga aacgacaaat
      241 ggggcctatg cgaaccattt cgatcaacgt gtttttaatg ctggtacatt tttaagaaac
      301 atacaagtaa catatacgca tgcacaacta aaaggtggta ataaagaacc ttatcgcatt
      361 ggtcttaaac tatcaaatgg tggttgggtt tatgtacaag gtctaacgca ttttgaggtc
      421 aatgaacatg atgaattttt aattgcaggt tttaattacg aaggtcaact cgctgcagca
      481 cttcaaatta gtgagcgacc atttaattta tagaggaggc atcaacatga ctgacgaaag
      541 acatgtatta gtaatatttc cacatcctga tgatgaaacc ttctcatctg caggcacatt
      601 agcaagttat atccaaaaag gcatacctgt aacatatgca tgtttaaccc taggacaaat
      661 gggcagaaat ttaggtaatc ccccatttgc aacacgcgaa tcattaccaa gtattcgtga
      721 gcgtgaacta gaagaagctt gtaaagttat tggtattact gatttaagaa aaatgggttt
      781 acgtgacaaa actgtcgaat ttgaacccta cgaacatata gatggtatga ttaaatcttt
      841 aatcgatgat acaaatccat cattgattat ttcattttat cctggatatg cagtacatcc
      901 tgatcacgaa gcaacagcag acgctgtaat tcgaacggtt gaacgcatgc ctaaagaaga
      961 acgccctcgt ttaactttag ttgcgttcag taatgatgca accgaagctc ttggagaacc
     1021 tgatattcaa aatgatatta cagattttaa agaacttaaa attaaggcat ttgaagcaca
     1081 tgcttctcaa acaggtccat ttttaaaaca attagcaagt cctgaaatcg atggtaaaca
     1141 acacagcttt ttaacagtcg aaccatattg gacatatcac tttaaatctt aacggaggaa
     1201 aaaaatgact gaatttgatt tatcgacacg agaaggtcgt tggaaacact ttggttccgt
     1261 agatcctatt gaaggcacga aacctactac taagaacgaa atgacagatt tacaaagtac
     1321 acataaagat tttttatttg aaatagaaga agttggtatt aaaaacttag tgtaccctgt
     1381 acttgttgac cagtatcaaa cagctggcac atttagtttt tcaacaagtt taacaaaaga
     1441 cgaaaaaggt attaatatga gccgtataat tgaaagtgtt gaaaagcact atgataatgg
     1501 tattgaactt gaatttaata cactttatca ggtgttacgc actttacaaa cgaatatgaa
     1561 acaaaatgcg gcaggcgttg atgtttctgg gaaatggttc tttgaccgct atagtccaac
     1621 cacaaatatt aaagcagttg gtaatgccga tgtcacttat ggattagcaa ttgacggtga
     1681 taaagttaca cgtaaagaac ttactattga agcaactgtc acaacgctat gcccttgttc
     1741 aaaagaaata agtgagtatt cagcgcacaa ccaacgtggt gttgtcactg ttaaaacata
     1801 tattaataaa gatcaaaaca tagttgatga ctataaaaac aaaattttag atgcaatgga
     1861 agctaatgca agttcaattc tataccctat tttaaaacgt cctgatgaaa aacgtgtgac
     1921 agagcgtgca tatgaaaatc cacgttttgt cgaagactta attcgtttaa ttgccgcgga
     1981 cttagttgaa tttgattggt tagacggttt cgatatcgaa tgtcgtaatg aagagtctat
     2041 ccatcaacat gatgctttcg ctaaattaaa gtatcgcaaa taatat
//
LOCUS       DAPDIM010000138         2085 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000138 DAPDIM010000000
VERSION     DAPDIM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2085
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.145"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(667..1683)
                     /locus_tag="RFE25_002810"
     CDS             complement(667..1683)
                     /locus_tag="RFE25_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="retron St85 family RNA-directed DNA polymerase"
                     /protein_id="HDU2817795.1"
                     /translation="MEKIENEIVNKTYLAINSLEELRNMIGIKSDYFYKCLYVNDHFY
                     NVIKIPKRKKDEYRELMIPNMALKNIQRWILDNVLYRRQVHKCATGFVPRKSIVNNAI
                     PHVGQKYILKMDIENFFPSITFKQVRKIFSEMGYKFELATALANLCTVNNQLPQGAPT
                     SPYIANIIFYNIDKRIFSYCQKNNLRYTRYADDITISGSNKVSFSKEIIREIVNQYNF
                     RINESKTIMFKPGDRKKVTGIIVNEKISVPKTLIREVRKQIYFVNKFGLEEHLIRNNY
                     SLDYEQQFIMSIYGKISFIKMIDFKKGVSLQKKFNEVLGNIESSNMYRDNIDFDDIEL
                     HWIN"
BASE COUNT          707 a          344 c          236 g          798 t
ORIGIN      
        1 tttaatataa aacctaaaaa gtagaaacac cagcatcgca acaataaaat aaacaggaat
       61 aaaagctttc ttccaaaata tagaatcttt caattaggtc actccttatt ttgataatac
      121 tctttaatta aggctcttga gttatcgtcc ggtcgttctt tcccttgaac cactatgatt
      181 agaacacaat cgtctggtta tcgtccaccc tccgcaagct aaatgacaat ttaataatgt
      241 acacttttga ttgtgtaaac atgtacaaat tatacgtgta aatcaataat ccatagttga
      301 attaattcta ttcctaagac attaaataaa ggaaagtcca tttatactct acacatttca
      361 tattccccac acaaacgcaa aaaaacacct cgacataaca tcgaggtgtt ttgtatatat
      421 cgtccgacaa ttaacgtttt aagaaatgag gtgaacgacg agctgcttta agacctggtt
      481 tactttagga tttcgtatag ttgcatatac tgtcttaagg catgatatta aaggatttct
      541 aatttttttg atagtattgg gtttcctcta atttaaccta ggggtattaa aatataataa
      601 aaatctgctg gctggtggta aatttcaaaa gaaatattaa ctaaaatata ttaattatta
      661 agcggtttaa tttatccaat gtagttctat atcatcaaag tcaatattat ctctgtacat
      721 gttagacgat tctatattac ctagtacttc attaaatttc ttttgtaaac taacgccttt
      781 cttgaaatca atcattttaa taaaactgat ttttccatat atactcataa taaattgctg
      841 ctcataatcc aatgaataat tatttcgaat taagtgttct tctaatccaa acttatttac
      901 aaaataaatt tgcttcctga cctctcttat taaagtttta ggaaccgata ttttttcatt
      961 aactataata ccagtaactt tttttctgtc tcctggttta aacataattg tcttactttc
     1021 attaattcta aaattatatt ggtttactat ttccctgata atttctttac taaaacttac
     1081 tttattagat ccagaaatag taatatcatc agcatatcga gtatatctca aattattttt
     1141 ttgacaataa gaaaagattc ttttatctat attgtaaaag atgatattag ctatatatgg
     1201 actggttggt gcaccttgag gcaactgatt attcactgta cacaaatttg cgagtgctgt
     1261 cgcaagttca aatttatagc ccatctcaga aaatattttt ctaacctgct taaatgtgat
     1321 actcggaaaa aagttttcta tatccatttt caatatatat ttctgcccaa cgtgtgggat
     1381 tgcattgttc actattgatt tcctaggaac aaaaccagtt gcacatttat gaacttgcct
     1441 tctgtacaat acattatcta aaatccacct ttggatattt ttgagagcca tattaggaat
     1501 catcaattct ctatattcat ctttttttcg tttaggtatt ttgataacat tataaaaatg
     1561 gtcattcaca taaagacatt tataaaaata gtctgattta ataccaatca tatttcttaa
     1621 ttcttccaaa gaattaattg caagatatgt cttattaact atttcattct caattttctc
     1681 catttaattc tccatttttt atctaaatga gcaactcttg ctaaaccatc ttcttttaat
     1741 tattacatta tttagtcgtt aggggccccc ctaactatta aataatataa ataattatct
     1801 caaaaaatga cctcttaaat taaaataatt atttatagta aaattttcga agaaaaattt
     1861 actgtaatca attgtatacc ttaattctta gataagacga ctcgcttatc agacactctt
     1921 gctcatttta tttattacca tcaaaatttt tctgctgatg taatccgtta ctcttaaatt
     1981 cataaagtat attacttaaa gttatttttt ctaatccata tttttttagt aattctattc
     2041 ctgcataagt aataatataa aaatctgttt gtttaattag aaatt
//
LOCUS       DAPDIM010000139         2033 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000139 DAPDIM010000000
VERSION     DAPDIM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2033
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.146"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(210..722)
                     /locus_tag="RFE25_002811"
     CDS             complement(210..722)
                     /locus_tag="RFE25_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817796.1"
                     /translation="MKQQMLSKVLLSTVVVMGSIAGSSLVMDDNAHAEQKSDNIGKLN
                     QKNESTLHLSFEKGIKGTVDKNGKLTLSDGKTSKVMPTNAKDKKGNDVVLVYKKVKDG
                     FDVQVIKSSQERKTNWVKCGLGTVGGAGTGGLGGASAASVIPGLGTVAGAIIGGVSGG
                     ATGAAASCFG"
     gene            complement(840..1277)
                     /locus_tag="RFE25_002812"
     CDS             complement(840..1277)
                     /locus_tag="RFE25_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3102 domain-containing protein"
                     /protein_id="HDU2817797.1"
                     /translation="MAGQSIFETGRRLKHVKENDLAHGEFGKWLEKVGLDKYQASRFI
                     KVANEQSKLHSSANLGLKALYQIATIPVEHREEKQQTSSGEMKTPYEMTNKEREEFKR
                     QLKQRDEENAQLQSQMEQAQRSEEIARKQYKYGLNNYIFTIKF"
     gene            complement(1419..>2033)
                     /locus_tag="RFE25_002813"
     CDS             complement(1419..>2033)
                     /locus_tag="RFE25_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HDU2817798.1"
                     /translation="SSDTSKTDSIVKMVATFSSVMSNRKNKPLKHYINTHNGVPLWIL
                     VNYLTLGNVSKMYSNLDDDLRLEVAKDYKRKLERDYKTRVQITPSDVDSILQQAHMFR
                     NVCAHEERLYDYKIDRAKSRANIFANYNKIYDKEYVPTMNGSYVFDLLISLCLFLNKH
                     DYIKLVKNMDKLISNYSHSFYTITIDDLYTKMNFPDQTKILDML"
BASE COUNT          623 a          401 c          268 g          741 t
ORIGIN      
        1 taattgtaac ttaattaatg tctattatag ttatatataa tagaagcaaa acctaaaatg
       61 actataaaag ctatcaaaac ataaactgaa aaattatcag ttctaatata aaacttaaaa
      121 agtaagaaca ttacaaaagc aactataaaa tagacaggaa taaacgactt tcgccaaagt
      181 atagagtttt tcatgaattc actctcctat caaccgaaac atgacgctgc ggcacctgtg
      241 gcaccaccag aaaccccacc aataatagca cctgcaacag ttcctaaacc tggtataact
      301 gaagctgcac tagcaccgcc tagcccacca gtgccagcgc ctccaactgt tcctagacca
      361 catttaaccc agttagtttt tctctcttga ctagatttaa ttacttgaac atcaaatcca
      421 tctttaacct ttttataaac caaaacaaca tcgttacctt ttttatcttt agcattagtt
      481 ggcatcactt ttgacgtttt tccatcagat aatgttaact taccattttt gtcaacagtc
      541 cctttaatac ccttttcaaa tgaaagatgc aaggtacttt catttttttg attcagtttc
      601 ccgatattat cacttttttg ttcagcatga gcgttgtcat ccattacaag agaagatcct
      661 gctattgatc ccataactac gactgtactt aataatactt ttgataacat ttgctgtttc
      721 ataataaaaa ctccttttaa aatttttaca ttttaatttt atcagttctt actataacgc
      781 tttaccaaaa tttcttaagt gcaataaaat cattcctaat tgtaaaaaat ggcgtgtgtc
      841 taaaatttta tagtaaaaat ataattattt aatccatatt tatattgctt tctcgctatc
      901 tcctccgaac gttgtgcttg ttccatttgt gattgaagtt gtgcgttttc ttcatcgcgt
      961 tgtttgagtt ggcgcttaaa ttcttcacgt tctttattgg tcatttcgta tggtgttttc
     1021 atctctcctg aagacgtttg ttgtttttct tctcgatgct ctactggaat agttgctatc
     1081 tgataaagcg ctttaagtcc taaatttgcg ctcgagtgca attttgattg ttcatttgca
     1141 actttgataa acctgctagc ttggtactta tctaacccaa ctttttcaag ccacttacca
     1201 aactctccgt gcgctaagtc attttctttc acatgcttca atcttcggcc agtctcgaat
     1261 atcgactgac cagcgatgtt tgaagtcgta tttcacgacg tcacacttac gattagcata
     1321 tctagttaca gaatcttatc ccccactgca acacagggcg tttctcagcg tcttaaaata
     1381 aaaaaacgcc actcgtaagt gacattaaaa aatatctttt ataacatatc cagtattttt
     1441 gtttgatctg gaaaattcat ttttgtatat aggtcatcta tagtaattgt atagaaagaa
     1501 tgtgaataat tacttattag tttatccata tttttcacca attttatgta atcatgttta
     1561 ttcaaaaata gacatagtga aatcaacaaa tcgaatacat aactaccatt cattgtagga
     1621 acgtattctt tatcgtatat tttgttataa ttggcgaata tattagctct acttttagcc
     1681 ctgtctattt tataatcata caatctttct tcatgcgcac acacgttacg aaacatatgt
     1741 gcttgttgta gtatactgtc tacatctgat ggagttattt gaacacgtgt tttataatct
     1801 ctttccaatt tccttttata gtctttagca acttccaatc gaagatcatc atccaaattg
     1861 gaatacattt ttgaaacatt acctaaagtt aaataattca ccaatatcca tagtggcact
     1921 ccattatgag tattaatata atgttttaat ggtttatttt ttctattact cataaccgag
     1981 ctaaatgtag caaccatttt cacgatgcta tctgtcttac ttgtgtcaga tga
//
LOCUS       DAPDIM010000140         1987 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000140 DAPDIM010000000
VERSION     DAPDIM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1987
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.147"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..570)
                     /locus_tag="RFE25_002814"
     CDS             complement(<1..570)
                     /locus_tag="RFE25_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="HDU2817799.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHH
                     STVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDI
                     WLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSK
                     YLNNLIEQDHRHIKVRKTRYQSINTAKNTL"
     gene            complement(807..902)
                     /locus_tag="RFE25_002815"
     CDS             complement(807..902)
                     /locus_tag="RFE25_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDU2817800.1"
                     /translation="MLEILVHITTTVISGCIVALFTHWLRNRNDK"
     gene            complement(1380..1952)
                     /locus_tag="RFE25_002816"
     CDS             complement(1380..1952)
                     /locus_tag="RFE25_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817801.1"
                     /translation="MVLTSTALLFSSFEPVVHAAENKEVVKTVENDNVEFNELLEGQE
                     YIWEVLSRDDEGFKMFLDEQRAFNPNFDNDVLLAKQEGALNSSVFANNSMTLNSNKPT
                     PRGPIGATLKAIKALSPSLRHGGTAISWIIKPLSRKHAVLVKKYSRKMSNAIDRLDKS
                     TKSAVENAFVKAGIPRSDAKTLTYIVFLVI"
BASE COUNT          668 a          342 c          276 g          701 t
ORIGIN      
        1 taaagtattc tttgctgtat tgatactttg ataccttgtc tttcttactt taatatgacg
       61 gtgatcttgc tcaatgaggt tattcagata tttcgatgta caatgacagt caggtttaag
      121 tttaaaagct ttaattactt tagccattgc taccttcgtt gaaggtgcct gatctgtaat
      181 taccttttga ggtttaccaa attgtttaat gagacgtttg ataaacgcat atgctgaatg
      241 attatctcgt tgcttacgca accaaatatc taatgtatgt ccctctgcat caatggcacg
      301 atataaatag ctccattttc cttttatttt gatgtacgtc tcatcaatac gccatttgta
      361 ataagctttt ttatgctttt tcttccaaat ttgatacaaa attggggcat attcttgaac
      421 ccaacggtag accgttgaat gatgaacgtt tacaccacgt tcccttaata tttcagatat
      481 atcacgataa ctcaatgcat atcttagata gtagccaacg gctacagtga taacatcctt
      541 gttaaattgt ttatatctga aatagttcat acagaagact cctttttgtt aaaattatac
      601 tataaattca actttgcaac agaatctttt atagtatcaa agaaaattaa taattctaat
      661 tatagagtta cacttacgtt tcttatgttt ttgcattcct ctactaacca gtgttataat
      721 atgattaaca agaattctag cgtgaataca ccaatcccct cactattgcc gtagtgaggg
      781 gattttttag gtgtgactat agtcgcctat ttatcgttgc gattgcgtag ccaatgcgta
      841 aataacgcaa caatacaacc actgatgact gtggtcgtga tgtgaacaag aatttctagc
      901 atgaataaca cctcctctct gcgtctaaat ttgacgcctg agagataggc gactctatta
      961 ttataccatc tgtgaatata caagcatatc tacttccgat aagtcgtctt atgttatata
     1021 acttcgtttt ttatagtatc aagacaaaag aagaaacgca gttcaaaatc atcacctaaa
     1081 ttcattaatc taaagaaaaa acggtgtaat aaatagtgaa tattatagtc tattaaagaa
     1141 tagatttaaa aacactctaa aaggtgcatt aaagatttgt aaaactttaa tatatccttt
     1201 ttaggtgaaa acttatgata attgtaggtt ctctcattat ctatgattat taattttaac
     1261 tgtatctaga aaatcatcac cccaatcaca aattgaaaat actactttat caagataaga
     1321 aaaaagaaaa aaacttgccc taagatttta taaaatctta gggcaagtca gctcaatatc
     1381 taaataacta aaaatacaat ataagttaaa gttttcgcat cacttcttgg tatacctgct
     1441 ttaacaaaag cattttcaac agctgatttc gtagacttat ctaacctatc aattgcatta
     1501 gacatctttc ttgaatattt ttttactaga acagcatgtt ttctacttaa tggtttaatg
     1561 atccaagata tagcagttcc accatgtctc aaagaaggtg atagagcctt aatagctttt
     1621 aaagttgcac cgataggacc tctaggagta ggcttatttg agtttaaagt catagaatta
     1681 ttagcaaata ctgaagaatt taaagcacct tcttgttttg ctagtaaaac atcattatca
     1741 aaattaggat taaaagctct ttgctcatct agaaacattt taaatccttc atcatctcta
     1801 gataaaactt cccaaatata ttcttgtcct tctaacaatt cattgaattc tacattatca
     1861 ttttctactg ttttaacaac ttccttattt tctgcagcat gaactacagg ttcaaaacta
     1921 gaaaataata atgcagtaga tgttagtacc aaagtatttt taataaaaaa actttttaaa
     1981 ttcttca
//
LOCUS       DAPDIM010000141         1915 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000141 DAPDIM010000000
VERSION     DAPDIM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1915
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.148"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            6..398
                     /locus_tag="RFE25_002817"
     CDS             6..398
                     /locus_tag="RFE25_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2817802.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            399..1838
                     /locus_tag="RFE25_002818"
                     /note="aph(2'')-Ia"
     CDS             399..1838
                     /locus_tag="RFE25_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HDU2817803.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          806 a          138 c          326 g          645 t
ORIGIN      
        1 agtttatgga agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag
       61 gatttcttaa tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag
      121 gatttgcata ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact
      181 caataggaat gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta
      241 ttaaggaata ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta
      301 atcctagagc ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa
      361 tagtatatgt atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa
      421 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
      481 aaagagtatt agaattttat ggtggtagag ataaaaaata tacattagaa tcattaaaaa
      541 aacattatac agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg
      601 ttcctattgg atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt
      661 atccaaaaac tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt
      721 ggagtaaagg aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa
      781 gaaatgctaa tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat
      841 accaaaaatc tggttttaga attattgaag atttgccaga acatgaatta cacgagggca
      901 aaaaagaaga ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg
      961 caatgaaata tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa
     1021 tcggtagtgg ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa
     1081 aatttagtac taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa
     1141 atacaaattt agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg
     1201 aattatctat actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt
     1261 ctactatgtc agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac
     1321 aaatgcacgg tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg
     1381 tattagaaga gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa
     1441 aagattatat agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa
     1501 agtgtttatg ccataatgat tttagttgta atcatctatt gttagatggc aataatagat
     1561 taactggaat aattgatttt ggagattctg gaattataga tgaatattgt gattttatat
     1621 acttacttga agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa
     1681 tgtatggaaa tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt
     1741 atcctattga aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg
     1801 gtagaaaaga aatttataaa aggacttata aagattgatt atataatata tgaaaagcta
     1861 ttataaaaga cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaag
//
LOCUS       DAPDIM010000142         1864 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000142 DAPDIM010000000
VERSION     DAPDIM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.149"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            130..741
                     /locus_tag="RFE25_002819"
     CDS             130..741
                     /locus_tag="RFE25_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5080 family protein"
                     /protein_id="HDU2817804.1"
                     /translation="MEFLLLIVVAGLYYIIYLTAVMYSEKIVVLPIIIYAILFVIIGI
                     TYIFIGDSYDQLTNFNVILYMGSLFYAWMAIRNLWNRPLLLKYKNITDSSSGIVNKSE
                     YNSVESLRINIEIAKYKGIISLIVAIVLTVLMTLKSTPQITAETRDLSISFFILSLFI
                     IIIFAVWDLFIRVRKGAFAFVVIRPILFSCWIFILNMILSRLL"
     gene            876..1094
                     /locus_tag="RFE25_002820"
     CDS             876..1094
                     /locus_tag="RFE25_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817805.1"
                     /translation="MENQKQGNGLKIATWVFIVLTVVTPLFGIGSIVCSINYKKYDAE
                     KGSKLLQIAIIVTIIAFVLNLLAYLGLR"
     gene            1226..1726
                     /locus_tag="RFE25_002821"
     CDS             1226..1726
                     /locus_tag="RFE25_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01741 family protein"
                     /protein_id="HDU2817806.1"
                     /translation="MTFEEKLSQMYNEIANKISSMIPVEWEKVYTMAYIDDEGGEVFY
                     YYTEPGSNELYYYTSVLNKYDISESEFMDSAYELYKQFQNLRNIFKEEGYEPWTSCEF
                     DFTKEGELKVSFDYIDWINTEFDQLGRQNYYMYKKFGVIPEMEYEMEEVKEIEQYIKE
                     QEEAEQ"
     gene            1737..>1864
                     /locus_tag="RFE25_002822"
     CDS             1737..>1864
                     /locus_tag="RFE25_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF600 family protein"
                     /protein_id="HDU2817807.1"
                     /translation="MTFEEKISKLYNEIANEISSMIPVEWEKVYTMAYIDDGGGEV"
BASE COUNT          709 a          178 c          348 g          629 t
ORIGIN      
        1 tgtgaagtat acttaaatta agaaaatcaa cttcaacgta tatcaccata ttattttata
       61 ctcaatgatg tgaatggatt taagtggatt gatattaaag taaaagttat ggaatattga
      121 ggtgcgaata tggagttctt attattaatt gtcgtagccg gactgtatta tattatatat
      181 ttaactgctg tgatgtattc tgaaaaaata gtagtattgc ctataatcat ctatgccatt
      241 ttgtttgtaa taattggtat cacttatatc tttataggcg acagctatga tcaattaaca
      301 aatttcaatg tgattttgta tatggggagt ttgttttatg catggatggc tattagaaat
      361 ctttggaaca gaccactatt actaaaatat aagaacatta cagatagttc aagtggaata
      421 gttaataaat ctgaatacaa ttcagttgaa agcttacgta taaatattga aatagctaag
      481 tataaaggga ttatttcttt gatagtagct atagtactaa cggtattaat gacattaaag
      541 tcaacacctc aaatcactgc agaaacacgt gacttaagta tctcattttt catactcagc
      601 ttatttatca ttattatatt tgcagtttgg gatttgttta ttagagttag aaaaggagcg
      661 tttgcttttg ttgtaataag gccaatatta ttcagttgtt ggatatttat tttgaatatg
      721 attttatcaa gattattata attgtattac atataggtgt gggtaaattt tatttatgaa
      781 atgatgaaaa agtatatact attaatatct tttttactat aattataaat agttaaataa
      841 attgaaagac aaaataatga gtaggagtta atgagatgga aaaccaaaaa caaggcaatg
      901 gcttaaaaat tgcaacatgg gtatttattg tattaacagt agttacaccg ctatttggta
      961 ttggaagtat tgtttgtagt attaattata aaaaatacga tgctgaaaaa ggttcgaagt
     1021 tattgcaaat tgcaattatc gtaacaataa ttgcttttgt tttaaattta ttagcatatt
     1081 taggtttaag ataagtaaaa cgaatttgaa gaagcattaa gcgacatttg ggtgttgttt
     1141 aatgcttttt atttaacgga aataagtgta gagaataaat taatagttta atcaagagat
     1201 atttcgaaca cataggggcg ataacatgac tttcgaagaa aaattaagtc aaatgtacaa
     1261 cgagattgcg aataagatta gtagcatgat accagtagag tgggaaaaag tatatacaat
     1321 ggcttatata gatgatgaag gtggagaagt gttctactat tacacagaac ctggaagcaa
     1381 tgaattatac tactatacta gtgtattaaa taaatatgat atatcggaat cagaatttat
     1441 ggactcagcg tatgagttgt ataaacaatt tcaaaattta agaaatatat ttaaagaaga
     1501 aggatatgaa ccatggacat catgcgaatt tgattttaca aaagaaggtg aattaaaagt
     1561 ttcatttgat tatatagatt ggatcaatac agagtttgat caattgggcc gtcaaaatta
     1621 ttatatgtac aaaaaatttg gggttatacc agaaatggaa tatgaaatgg aagaagttaa
     1681 agaaatcgaa caatatatta aagagcaaga agaagctgaa caatagaggt gataacatga
     1741 ctttcgaaga gaaaataagc aaattatata atgagattgc gaatgagatt agcagtatga
     1801 taccggtaga gtgggaaaaa gtatatacaa tggcttatat agatgatgga ggaggtgaag
     1861 tatt
//
LOCUS       DAPDIM010000143         1817 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000143 DAPDIM010000000
VERSION     DAPDIM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1817
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.150"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            137..1741
                     /locus_tag="RFE25_002823"
     CDS             137..1741
                     /locus_tag="RFE25_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /protein_id="HDU2817808.1"
                     /translation="MYQNYTINQLCLPIDLEIKLEENDFAHAIVQFVDSIPDEVFLPY
                     YQSMGRPQYHPRMLLSIILCAYIQGVYSGRQIQNMLIDSIRMRYLSQEQFPNFRTINR
                     FRVHPIMNDILDHSFVQFRELLVQSGLISGSALYIDGTKIEADANKYSFVWKKSILKY
                     KDSLDQKALENYQQMVETKILPELIDDLKDELSIEEIERIRQSLEEKENQLIEAIDQT
                     ETVEERKLLRKEKSEVHKQKKRFDDFAQRKMSYEEQLVIMGVRNSFSKTDHDATFMRM
                     KEDHMLNGQLKPGYNIQLATENQFALAYDCYPNPTDTRTFIPFLEKIESKIGLPENIV
                     ADAGYASEENYCYVLDETESTPIIPHQGYLKEKKRAHKQNQFHRDNWTYNELDDYYIC
                     PNQKRVVFSHYSQRKDRNGFIRNFKIYECEDCTGCPLREKCTKAKEGKNRRLNINPTW
                     EYIKIKANEKIESKETASYYAQRKIDVETVFGNIKQNMKFKRFHVRGAEKIFKEMGLV
                     FLAHNFRKLVTRVRKYEGKTIIQNQI"
BASE COUNT          678 a          291 c          326 g          522 t
ORIGIN      
        1 ctatatgaaa aatagaggtc tttccattta gatagtagtg gaaagacctc tatttatctt
       61 ttgaaagtga atacaaaaat aaagcacact ctgctataat ataggtgatt aatccatttg
      121 agagaggtgc tttatcatgt atcaaaatta taccataaac caactttgtt tgcctataga
      181 tcttgaaatt aaattagaag aaaatgattt tgctcatgcc attgtgcagt ttgttgactc
      241 tattcccgat gaagtctttc ttccttatta tcaatctatg ggtagacccc aatatcatcc
      301 tcgtatgcta ctttccatta ttctttgtgc ctatattcaa ggggtttatt cgggccgcca
      361 aatacaaaat atgctgatag atagtattcg gatgcgctac ttatctcaag agcaattccc
      421 taactttcgt actattaatc gttttcgcgt tcatccgatt atgaacgata ttctagatca
      481 ttcatttgtt caatttcgtg agctactggt tcaaagtggc ttaatcagtg gcagtgctct
      541 atacattgat ggtacaaaaa ttgaagcgga tgcgaataaa tactctttcg tttggaaaaa
      601 aagtatttta aagtataagg atagccttga tcaaaaagcc cttgaaaact accaacaaat
      661 ggtggaaaca aaaatcttac ctgagttaat agatgattta aaggatgaac tttctataga
      721 agagattgaa aggattcgtc aatctttgga agaaaaggaa aatcaattaa ttgaagcgat
      781 tgaccaaacc gaaacagtag aagaacgaaa attacttcgt aaagaaaaat ctgaagttca
      841 taagcagaag aagcgattcg atgattttgc ccaaagaaaa atgagctacg aagaacaatt
      901 agtgattatg ggtgtacgca atagtttctc aaagacggat catgacgcta cttttatgcg
      961 aatgaaagaa gatcacatgc ttaatggcca actaaaacca ggttataata ttcaacttgc
     1021 gacagaaaat caatttgctc ttgcttatga ttgttatcca aatccaacag atacacgaac
     1081 atttatccca tttcttgaaa agattgaatc aaaaataggt ttaccagaaa atattgtcgc
     1141 agatgccggt tatgcaagtg aagaaaatta ttgttatgtg ttagacgaaa cagaatccac
     1201 ccccatcatt ccgcatcaag gttacttaaa agagaagaaa cgcgcccata aacaaaatca
     1261 gtttcatcga gataattgga cttacaacga gttggatgat tactatattt gtcccaatca
     1321 gaaaagagta gtgttctcac attattcaca acgtaaagat agaaatggat ttattcgaaa
     1381 cttcaaaatc tatgaatgtg aagattgtac aggatgtcca ttgagagaga aatgtaccaa
     1441 agcaaaagaa ggaaaaaatc gacgtttgaa tattaatcca acctgggaat atataaaaat
     1501 aaaagcgaat gaaaagatag aaagcaaaga aacagcctca tactatgcgc agcgaaagat
     1561 agatgtcgaa acagtttttg gaaacattaa acaaaatatg aaatttaaaa gattccatgt
     1621 ccgaggagct gaaaaaattt ttaaggaaat gggacttgta tttcttgcgc acaattttag
     1681 gaaattagta actagagtaa ggaaatatga gggaaaaaca atcatacaaa accaaatata
     1741 gggggaaaat cctctatatt tcatccaaaa aaaacaaaaa tcgaagacat ctttcacggg
     1801 tgccttcgat tttttgg
//
LOCUS       DAPDIM010000144         1795 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000144 DAPDIM010000000
VERSION     DAPDIM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1795
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.151"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            227..1747
                     /locus_tag="RFE25_002824"
     CDS             227..1747
                     /locus_tag="RFE25_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDU2817809.1"
                     /translation="MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILG
                     QAQTGTGKTGAFGIPLIEKVVGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVT
                     VFGGMPIERQIKALKKGPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGF
                     IDDMRFIMDKIPAVQRQTMLFSATMPKAIQALVQQFMKSPKIIKTMNNEMSDPQIEEF
                     YTIVKELEKFDTFTNFLDVHQPELAIVFGRTKRRVDELTSALISKGYKAEGLHGDITQ
                     AKRLEVLKKFKNDQINILVATDVAARGLDISGVSHVYNFDIPQDTESYTHRIGRTGRA
                     GKEGIAVTFVNPIEMDYIRQIEDANGRKMSALRPPHRKEVLQAREDDIKEKVENWMSK
                     ESESRLKRISTELLNEYNDVDLVAALLQELVEANDEVEVQLTFEKPLSRKGRNGKPSG
                     SRNRNSKRGNPKFDSKSKRSKGYSSKKKSTKKFDRKEKSSGGSRPMKGRTFADHQK"
BASE COUNT          657 a          270 c          354 g          514 t
ORIGIN      
        1 attttttata atgattattc gaatgatgcg taacgcttac atcttatcta atgctagctt
       61 tttgacaaaa atatgacaat caattaatgt gattctaata aatattcgca aattgcttta
      121 ttgcgattaa atttttttgg tggtactata tagaagttga tgaaatatta atgaacttat
      181 atgcaaaagt atattgagaa ataaacaggt aaaaaggaga attattttgc aaaattttaa
      241 agaactaggg atttcggata atacggttca gtcacttgaa tcaatgggat ttaaagagcc
      301 gacacctatc caaaaagaca gtatccctta tgcgttacaa ggaattgata tccttgggca
      361 agctcaaacc ggtacaggta aaacaggagc attcggtatt cctttaattg agaaagtagt
      421 agggaaacaa ggggttcaat cgttgatttt agcacctaca agagaattgg caatgcaggt
      481 agctgaacaa ttaagagaat ttagccgtgg acaaggtgtc caagttgtta ctgtattcgg
      541 tggtatgcct atcgaacgcc aaattaaagc cttgaaaaaa ggcccacaaa tcgtagtcgg
      601 aacacctggg cgtgttatcg accatttaaa tcgtcgcaca ttaaaaacgg acggaattca
      661 tactttgatt ttagatgaag ctgatgaaat gatgaatatg ggattcatcg atgatatgag
      721 atttattatg gataaaattc cagcagtaca acgtcaaaca atgttgttct cagctacaat
      781 gcctaaagca atccaagctt tagtacaaca atttatgaaa tcaccaaaaa tcattaagac
      841 aatgaataat gaaatgtctg atccacaaat cgaagaattc tatacaattg ttaaagaatt
      901 agagaaattt gatacattta caaatttcct agatgttcat caacctgaat tagcaatcgt
      961 attcggacgt acaaaacgtc gtgttgatga attaacaagt gctttgattt ctaaaggata
     1021 taaagctgaa ggcttacatg gtgatattac acaagcgaaa cgtttagaag tattaaagaa
     1081 atttaaaaat gaccaaatta atattttagt cgctactgat gtagcagcaa gaggactaga
     1141 tatttctggt gtgagtcatg tttataactt tgatatacct caagatactg aaagctatac
     1201 acaccgtatt ggtcgtacgg gtcgtgctgg taaagaaggt atcgctgtaa cgtttgttaa
     1261 tccaatcgaa atggattata tcagacaaat tgaagatgca aacggtagaa aaatgagtgc
     1321 acttcgtcca cctcatcgta aagaagtact tcaagcacgt gaagatgaca tcaaagaaaa
     1381 agttgaaaac tggatgtcta aagagtcaga atcacgcttg aaacgcattt ctacagagtt
     1441 gttaaatgaa tataacgatg ttgatttagt tgctgcactt ttacaagagt tagtagaagc
     1501 gaacgatgaa gttgaagttc aattaacttt tgaaaaacca ttatctcgca aaggccgtaa
     1561 tggtaaacca agcggttctc gtaacagaaa tagtaagcgt ggtaatccta aatttgacag
     1621 taagagtaaa cgttcaaaag gatactcaag taagaagaaa agtacaaaaa aattcgaccg
     1681 taaagagaag agcagcggtg gaagcagacc tatgaaaggt cgcacatttg ctgaccatca
     1741 aaaataattt atagattaag agcttaaaga tgtaatgtct tgagctcttt tttgt
//
LOCUS       DAPDIM010000145         1620 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000145 DAPDIM010000000
VERSION     DAPDIM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1620
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.153"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(23..805)
                     /gene="seo"
                     /locus_tag="RFE25_002825"
     CDS             complement(23..805)
                     /gene="seo"
                     /locus_tag="RFE25_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type O"
                     /protein_id="HDU2817810.1"
                     /translation="MKNSKVMLNVLLLILNLIAICSVNNAYANEEDPKIESLCKKSSV
                     DPIALHNINDDYINNRFTTVKSIVSTTEKFLDFDLLFKSINWLDGISAEFKDLKVEFS
                     SSAISKEFLGKTVDIYGVYYKAHCHGEHQVDTACTYGGVTPHENNKLSEPKNIGVAVY
                     KDNVNVNTFIVTTDKKKVTAQELDIKVRTKLNNAYKLYDRMTSDVQKGYIKFHSHSEH
                     KESFYYDLFYIKGNLPDQYLQIYNDNKTIDSSDYHIDVYLFT"
     gene            complement(1019..1107)
                     /locus_tag="RFE25_002826"
     tRNA            complement(1019..1107)
                     /locus_tag="RFE25_002826"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1070..1072),aa:Ser,seq:gga)
     gene            complement(1162..1233)
                     /locus_tag="RFE25_002827"
     tRNA            complement(1162..1233)
                     /locus_tag="RFE25_002827"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1198..1200),aa:Glu,seq:ttc)
     gene            complement(1235..1309)
                     /locus_tag="RFE25_002828"
     tRNA            complement(1235..1309)
                     /locus_tag="RFE25_002828"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1275..1277),aa:Asn,seq:gtt)
     gene            complement(1327..1400)
                     /locus_tag="RFE25_002829"
     tRNA            complement(1327..1400)
                     /locus_tag="RFE25_002829"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1366..1368),aa:Gly,seq:tcc)
     gene            complement(1416..1491)
                     /locus_tag="RFE25_002830"
     tRNA            complement(1416..1491)
                     /locus_tag="RFE25_002830"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1456..1458),aa:His,seq:gtg)
     gene            complement(1505..1577)
                     /locus_tag="RFE25_002831"
     tRNA            complement(1505..1577)
                     /locus_tag="RFE25_002831"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1542..1544),aa:Phe,seq:gaa)
BASE COUNT          539 a          311 c          241 g          529 t
ORIGIN      
        1 atatccatca actttcagat tgttatgtaa ataaataaac atcaatatga tagtctgatg
       61 aatctattgt tttattatca ttataaattt gcaaatattg atctggtaaa tttcctttaa
      121 tataaaataa atcataataa aatgattctt tatgctccga atgagaatga aatttaatat
      181 aacctttttg tacatcacta gtcattctgt catacaattt atatgcatta tttaattttg
      241 ttcttacttt aatatcaagt tcttgtgcag taactttctt tttatctgta gtaacgataa
      301 atgtattaac atttacatta tccttataca cagctactcc tatattttta ggctcgctta
      361 atttattatt ttcatgaggt gttaccccac catatgtaca ggcagtatcc acttgatgct
      421 caccatgaca atgtgcttta tagtaaacac cataaatatc aacagtcttt cctagaaatt
      481 ctttagaaat cgctgatgag ctaaattcca cttttaaatc tttaaattca gcagatattc
      541 catctaacca attaatactt ttaaataata aatcgaagtc taagaatttt tctgtagttg
      601 atacaattga ttttactgtc gtaaatcgat tatttatata atcatcatta atattatgta
      661 aagcaatagg gtctacactt gacttcttac acaaactctc tattttagga tcttcttcat
      721 ttgcatatgc attgtttaca ctacatattg caattaaatt taaaattaat aataatacat
      781 ttaacattac tttactattt ttaataatat ccctccttca caaaattttt ttcttaataa
      841 actgaaaaat tctgttttta atctttaaat attcactaat attattagat tacgatttta
      901 aacttaacaa tcctacttac tattgaacaa acaaatttta aattaagtga ctcagataat
      961 agacaaaaaa ccttaaaaat agcgcttaaa atgggtaaaa ccattttaag cgctataacg
     1021 gagagtgagg gattcgaacc ctcgagacgc ttgtggcgcc tacacacttt ccaggcgtgc
     1081 tccttcggcc aactcggaca actctcctca ataataaata tgtaataaaa aaacagaagc
     1141 gatatttcac ttctgtttgt atgactccta cgggactcga acccgtgtta ccgccgtgaa
     1201 agggcggtgt cttaaccgct tgaccaagga gccatggctc cacaggtagg actcgaacct
     1261 acgaccgatc ggttaacagc cgatagctct accactgagc tactgtggaa taataataga
     1321 aaataatgga gcgggtgatg ggaatcgaac ccacaacatc agcttggaag gctgaggttt
     1381 tgccattaaa ctacacccgc taatgtaaac gattatgggg cggctgaagg ggatcgaacc
     1441 ctcgaatgtc ggaaccacaa tccgatgtgt taaccacttc accacaaccg ccatgaatta
     1501 agaatggttc aggacagagt cgaactgccg acacatggag cttcaatcca ttgctctacc
     1561 aactgagcta ctgaaccgta atggtaataa taatggcggt ctcgacggga atcgaacccg
//
LOCUS       DAPDIM010000146         1470 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000146 DAPDIM010000000
VERSION     DAPDIM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.154"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..646)
                     /locus_tag="RFE25_002832"
     CDS             complement(<1..646)
                     /locus_tag="RFE25_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2817811.1"
                     /translation="MMIHSRKLRLWLYLVLLAVFIGACGMKKEESSKDKQIKENFNKT
                     LSLYPTKNLEDFYDKEGFRDEEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRN
                     TRTTKGEFIVRELWEDKKGYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIEDFKFF
                     VQYGDFKDINDYKDGDISYNPNVPSYSAKYQLSNNDYNVKQLRKRYDIPTKKAPK"
     gene            complement(950..>1470)
                     /locus_tag="RFE25_002833"
     CDS             complement(950..>1470)
                     /locus_tag="RFE25_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3427 domain-containing protein"
                     /protein_id="HDU2817812.1"
                     /translation="LEDLIELSKYNNEKYQKGKNGLILYNKYSREDFSKIFNWNKNGS
                     SVIMGYMIRSQEMPIFITYDKHEDISDSTKYEDEFLSQDELKWFTKSNRTLKSKEVQK
                     ILSHRAKGIKMYIFVQKKDDDGIYFYYLGTAGYIEGSEKQDKMPNGSNVVTMDLALDK
                     AVRDDIYRYITN"
BASE COUNT          435 a          261 c          153 g          621 t
ORIGIN      
        1 gtttcggagc tttcttagtt ggtatatcat acctctttct aagttgcttc acattgtagt
       61 cattgttact caattgatat tttgcggaat aacttggaac attaggatta tatgaaatgt
      121 caccatcttt ataatcatta atatctttaa agtcaccgta ttgtacaaaa aacttaaagt
      181 cttcaatttc ttttcttaat ttatcatcag ctatcggttt agttgggata attttattat
      241 gttccatttt cactggatat tctttttctt tactacgtga gtatcctttt ttatcttccc
      301 ataattctct cacaataaat tcaccttttg tcgttctggt attgcggtct acatacagga
      361 ccaagcctct ggattccata ttctttccat ttgtttctat tgtcatttta gagtgaatta
      421 tccaagtccc tttatctcct ttttcaaact cttcatctcg aaaaccttct ttatcataaa
      481 agtcttcaag atttttagtt ggatataagc tcaacgtttt gttgaagttt tctttaattt
      541 gtttatcctt actgctttct tcctttttca ttccgcaagc gcctataaaa acagctaata
      601 atactaaata cagccaaagc ctcaactttc ttgaatgaat catcatttca catccccatt
      661 tttatttttg atgcaaagtt aagttcaaat tccaatatta ataatactag aggaaatttt
      721 atgattaaat cctcgtggat tttaattgtt agttgtattt ttcacatatc aacatcacaa
      781 attatttaaa aagcgcaaat atctttataa tttttattgg cctaaccaac taattaatta
      841 agataaattg cgcttatatt taaaataata acactgaaac ttcaatgtct ttacttatta
      901 caattgatgt ttaaatacat ctttactaac attcattttt cggtttacat taatttgtta
      961 tatagcgata tatatcatct cttacagctt tatcgagtgc taaatccatc gttactacgt
     1021 ttgaaccatt cggcatttta tcttgcttct ctgaaccttc tatatatcca gcagttccta
     1081 aataataaaa atatatacca tcatcatctt ttttctgtac aaaaatatac attttaattc
     1141 cttttgctct atgggacaaa attttctgaa cttcttttga ttttagcgtt ctattagatt
     1201 tagtaaacca ttttaattca tcttgactta aaaattcatc ttcatatttt gtactatcac
     1261 ttatatcctc atgcttatca taagtgataa atattggcat ttcttggctt cttatcatgt
     1321 atcccatgat tacagacgaa ccatttttat tccaattaaa tattttgcta aaatcttctc
     1381 ttgaatattt attatataaa atcagtccat ttttaccttt ttggtatttt tcattgttat
     1441 actttgataa ttcaataaga tcttctaaaa
//
LOCUS       DAPDIM010000147         1466 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000147 DAPDIM010000000
VERSION     DAPDIM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.155"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            190..591
                     /locus_tag="RFE25_002834"
     CDS             190..591
                     /locus_tag="RFE25_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl peptide receptor-like 1 inhibitory
                     protein"
                     /protein_id="HDU2817813.1"
                     /translation="MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLA
                     DQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRD
                     YYTFDLTRPLEENRKNIKVVKNGEIDSIYWD"
     gene            551..643
                     /locus_tag="RFE25_002835"
                     /pseudo
     CDS             551..643
                     /locus_tag="RFE25_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499655.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(960..1289)
                     /gene="ecb"
                     /locus_tag="RFE25_002836"
     CDS             complement(960..1289)
                     /gene="ecb"
                     /locus_tag="RFE25_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement convertase inhibitor Ecb"
                     /protein_id="HDU2817814.1"
                     /translation="MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNVEAAKKYDQYQ
                     TNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLV
                     LKYNTLK"
BASE COUNT          518 a          221 c          192 g          535 t
ORIGIN      
        1 caataatacc tcaaataaaa ataataccat caaattcatc attattcttt ttcgattgca
       61 ttaaacctta ttaatttgca cttaatttta attaatgaag tgttaactgg taaatgcatg
      121 aaaccgtttg taaaatagca gtgtactcgc attagtaagt acaaatttat tttacaggga
      181 gaacttatta tgaaaaaaaa tatcacaaaa actattatcg catctacagt aatcgctgca
      241 ggtcttttaa ctcaaactaa tgatgctaaa gctttcttta gttatgaatg gaaaggttta
      301 gaaatcgcaa aaaatttagc agatcaagct aaaaaggacg atgaacgtat tgataagtta
      361 atgaaagagt ctgataaaaa tctaactcct tacaaagctg aaactgttaa tgatctgtac
      421 cttattgtta aaaaattaag ccaaggtgat gtgaagaaag cagttgtcag aattaaagat
      481 ggtggtccta gagattacta tacttttgac ttaactcgtc ctttagaaga gaacagaaaa
      541 aatattaaag ttgttaaaaa cggtgaaatc gactcgattt attgggatta attaacatac
      601 tgaattaaat agttgtacgc caaacgttag aaaacaatgc taacgtattg gcgtgctttt
      661 ttattttaag taacttccaa tttatttagc atctttacga ctgtttaata aagcacgtat
      721 gattaacacg gttgccacta tatccgttac aatttttatg attgttaata cattcgattt
      781 ccttttcaca atagccacct cgcttgttca aaacataaac aactattgca ttcactttta
      841 agtaattatt tatatgattt atcccaataa gctcaccatt caaataaaca caatattata
      901 aaataattat acctttggat atagcaaaaa gccacactct atagcatggc ttctatcaat
      961 tattttaaag tattatattt taaaactaga tcgatttgtc tttgtaattt tttcttttca
     1021 tagctgtgtt ggaaatgaat taaattaaca gctctttgtg ctttacggtg tgttgcaaca
     1081 gttcttgtac gtttgaacaa gtttacagct ttttgtgcat ccacaacttt tttatttact
     1141 tgttttttaa agtttgtttg atactgatca tattttttag cagcttcaac gtttttagtt
     1201 tgtgcatgag attcaccggc aaacgttgat accgttaaac taatagcagc tatgcttaaa
     1261 attgatttcc caataaaatt ctttttcata attaataaca cctatcctca aatatttatt
     1321 ttgtatatat ttataataat agacagatac aaaaaactac attaactatt tattaactaa
     1381 acattaatat ttgtgtcact acatttctga atttcaagaa ttttgctact ccatatttta
     1441 accatcaaat tattgatata atttat
//
LOCUS       DAPDIM010000148         1396 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000148 DAPDIM010000000
VERSION     DAPDIM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1396
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.156"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..638)
                     /gene="sei"
                     /locus_tag="RFE25_002837"
     CDS             complement(<1..638)
                     /gene="sei"
                     /locus_tag="RFE25_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031927819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type I"
                     /protein_id="HDU2817815.1"
                     /translation="MKKFKYSFILVFILLFNIKDLTYAQGDIGVGNLRNFYTKHDYID
                     LKGVTDKNLPIANQLEFSTGTNDLISESNNWDEISKFKGKKLDIFGIDYNGPCKSKYM
                     YGGATLSGQYLNSARKIPINLWVNGKHKTISTDKIATNKKLVTAQEIDVKLRRYLQEE
                     YNIYGHNNTGKGKEYGYKSKFYSGFNNGKVLFHLNNEKSFSYDLFYTGDGLPV"
     gene            complement(673..1392)
                     /gene="sem"
                     /locus_tag="RFE25_002838"
     CDS             complement(673..1392)
                     /gene="sem"
                     /locus_tag="RFE25_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_058008129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type M"
                     /protein_id="HDU2817816.1"
                     /translation="MKRILIIVVLLFCYSQNHIATADVGVLNLRNYYGSYPIEDHQSI
                     NPENNHLSHQLVFSMDNSTVTAEFKNVDDVKKFKNHAVDVYGLSYSGYCLKNKYIYGG
                     VTLAGDYLEKSRRIPINLWVNGEHQTISTDKVSTNKKLVTAQEIDTKLRRYLQEEYNI
                     YGFNDTNKGRNYGNKSKFSSGFNAGKILFHLNDGSSFSYDLFDTGTGQAESFLKIYND
                     NKTVETEKFHLDVEISYKDES"
BASE COUNT          461 a          221 c          165 g          549 t
ORIGIN      
        1 acaggcagtc catctcctgt ataaaacaaa tcatatgaaa atgatttttc attatttaaa
       61 tgaaataaaa ctttcccatt attaaaacct gaataaaatt tagatttata tccatattct
      121 ttgcctttac cagtgttatt atgaccatat atattgtatt cttcttgaag atatcttctt
      181 aatttaacat caatttcttg agctgttact agttttttat tagttgctat tttgtcagta
      241 gaaattgttt tatgtttgcc attaacccaa agattaatag ggatttttct agcagaattt
      301 aagtattgtc ctgataaagt ggcccctcca tacatgtatt tagatttaca aggaccatta
      361 taatcaatgc caaaaatatc cagtttcttt cctttaaatt tacttatttc gtcccaatta
      421 ttagattctg agatcaaatc attggtacct gttgaaaatt cgagttgatt tgcaataggt
      481 aggtttttat ctgtgacgcc ttttaaatct atataatcat gttttgtata gaaatttctt
      541 aagttaccta caccaatatc accttgagca tacgtaagat ctttaatgtt aaaaagtaat
      601 ataaaaacta atataaaact atatttaaat tttttcatgg catttccttt actaagttat
      661 gattgaaata cttcaacttt cgtccttata agatatttct acatctaaat ggaatttttc
      721 agtttcgaca gttttgttgt cattatatat ttttaagaaa ctttcagctt gtcctgttcc
      781 agtatcaaat aagtcataag aaaatgatga accatcattc aaatgaaata atatttttcc
      841 tgcattaaat ccagaactaa attttgactt attaccataa tttcttcctt tatttgtatc
      901 attaaagcca taaatattat attcttcttg tagatatctt cttaatttag tatcaatttc
      961 ttgagctgtt actaactttt tattagttga tactttgtca gtagatatag tttgatgttc
     1021 tccattaacc caaagattaa taggaatacg tctagatttc tctaaataat cacctgctaa
     1081 tgtaactcca ccgtatatat atttgttttt caaacaatat ccactataac ttagaccata
     1141 tacatctaca gcatgatttt tgaatttctt tacatcatca acgttcttaa attcagctgt
     1201 tactgtcgaa ttatccatag aaaaaactaa ttgatgcgaa agatgattat tttcaggatt
     1261 aatactttgg tggtcttcaa ttggatagct accataatag ttcctaagat tcaaaactcc
     1321 gacatcagcg gttgcgatat gattttgcga atagcaaaac aataaaacaa caatgataag
     1381 tattcttttc atattt
//
LOCUS       DAPDIM010000149         1292 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000149 DAPDIM010000000
VERSION     DAPDIM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.158"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            88..>1292
                     /locus_tag="RFE25_002839"
     CDS             88..>1292
                     /locus_tag="RFE25_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1181 family transposase"
                     /protein_id="HDU2817817.1"
                     /translation="MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPS
                     ACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIV
                     DESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLP
                     EHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVK
                     TVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPNYT
                     IFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRRSYELVQGLR
                     KDLRLCNWPKFINRLNSVSKKSVSKGVWKVVKYYRKHQRMLRNTIYYPAFNNGAIEGI
                     NNKIKLIKR"
BASE COUNT          490 a          188 c          213 g          401 t
ORIGIN      
        1 cttcctgctt tttttaatac acaaaaagcg caattgcctc tataatttaa agtgaccaaa
       61 cccaaactaa aggagacaag tgcgcctatg tgtaatgata ccttagaatt actaagaata
      121 aaagatgaaa atataaaata tataaaccaa gaaattgacg tcattatcaa aggaaaaaaa
      181 gcaacagtgg ttaatgctgt actaacgtat aagccttcgg cctgttattg ttgtggagtt
      241 aaaaatgaag gacaaattca taaacatggt aagcgtgttt ctcgtattac tttacttaaa
      301 actcaagggt ataacacata cctcaactta gctaaacaac gttttaaatg cttagaatgc
      361 aatggcactt ttactgctaa aacgtcaatt gttgatgagt cgtgttttat ctcaagatgt
      421 gttactcaaa aagttataga agaagctact aaagttaaaa cagagattga tactgcagaa
      481 gataactgta tctctccatc tactgtaagt cgtattagaa ctaaagcggc taattcatta
      541 cgaattaaac cgtttaattg tttgccagaa cacatcgcta tggatgaatt taaaagcgtt
      601 aaaaatgtaa ctggatcaat gagtttcatt tttatagata atgatactca tgatgttata
      661 gatattttag aaaatagaac tacaagattc ttgcgtgcct atttcgagcg attcgattta
      721 aaaaatcgac aacaagttaa gacggttact attgacatgt atgaacccta tgtccgatta
      781 tttcgcgacc tatttcctaa tgcagctatt atttttgaca gattccatat cgttcaacat
      841 ttaaataggg aacttaataa gtatcgtgta caagttatga atgaataccg taataaaaaa
      901 ggacctaatt atacaatttt taagaataac tggaaagttc tattgatgga tactagtaaa
      961 accatattta gtaaatacag atggaataaa tcttttaagg cttataaacg ctcatctgac
     1021 attgtagaat tcatgctttc aaaagacgat atactacgac gctcctacga acttgtccaa
     1081 ggattaagaa aagatctaag gttatgtaat tggcctaaat ttattaatcg tttaaattca
     1141 gttagtaaaa agtctgtgag taaaggtgta tggaaagtgg ttaaatatta tagaaaacat
     1201 caaaggatgt taagaaatac aatttattac ccagcattta ataatggtgc tatagaagga
     1261 attaataata agataaaatt aatcaagcga at
//
LOCUS       DAPDIM010000150         1255 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000150 DAPDIM010000000
VERSION     DAPDIM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.159"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..319)
                     /locus_tag="RFE25_002840"
     CDS             complement(<1..319)
                     /locus_tag="RFE25_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HDU2817818.1"
                     /translation="MKPFESHNKQLKILRRRGMEVPSSAKRDLENENYYNIINGYKDL
                     FLELDVNGNFLVPDKYKQGTHFKEVFSLYKLDRKFRNVLLEYLLVFETHIKSRISYYF
                     SEKY"
     gene            complement(596..1165)
                     /locus_tag="RFE25_002841"
     CDS             complement(596..1165)
                     /locus_tag="RFE25_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDU2817819.1"
                     /translation="MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLK
                     KPHIKQYIQEQKDKIIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSG
                     KVQLVYNEHVELIEVPIKPSDRLKARDMLGKYHKLFTDKHDINGDVPIFINIGEWDGD
                     DEELDKTVKDVSNANPNHTVIVDDIPLED"
     gene            complement(1162..>1255)
                     /locus_tag="RFE25_002842"
     CDS             complement(1162..>1255)
                     /locus_tag="RFE25_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDU2817820.1"
                     /translation="KDISSVLECSEQSVRLWYETLLDKIVEVIE"
BASE COUNT          389 a          252 c          135 g          479 t
ORIGIN      
        1 tatatttttc gctaaaataa tatgaaattc ttgatttaat atgagtttca aatactaaca
       61 aatactctaa taaaacattc ctaaattttc tatctagttt gtataaagaa aagacttctt
      121 taaaatgagt accttgctta tatttatcag gaaccaaaaa attaccatta acatctagtt
      181 ctaaaaataa atctttataa ccatttatga tattataata attttcattt tctaaatctc
      241 ttttagcact actcggtact tccattcctc ttcttcttag aattttcaat tgtttattat
      301 gactttcaaa tggcttcata aatttacccc tataaaagta gccataaccc gaatagagtt
      361 atggctagat cgttatatat ataatacatt taattttatc ggttgtaaat aaataagaaa
      421 taacaaaaag agatatttta cacaattacc tcctttattt tattgctact cctcaaaccc
      481 accaatatta tcaataaaca ctggtgttgt tacatttaag tctactttct cagtaaataa
      541 gctatggtat caaactaatt agtattaatt tataaatagc atagcttcat tttcttcaat
      601 cctctaacgg tatatcatcc acaatcacag tatggttagg attagcgtta gatacatctt
      661 ttacagtttt atctaattcc tcatcgtctc cgtcccattc accaatgtta atgaatatag
      721 gaacatcccc gttgatatca tgcttatctg taaataactt atggtattta cccaacatat
      781 cacgagcttt taaacgatca cttggcttaa ttggcacctc tatcagttca acatgttcat
      841 tatagactaa ctgtactttg ccactttgtg gattctcttt atattcccca cgcttgacca
      901 caacttcttt cgtttctgtt tcgtcaccga ctgccgcatt cgtaagcaca tgtagtaact
      961 cttttgcagt taatacattc tcatctataa tcttatcttt ttgttcttgt atatattgct
     1021 tgatgtgtgg cttctttaat aacctacacc ctgtcacatg tgcactattt gcgctataac
     1081 ctgcttttat ggcactttgt gtcacattaa gtgttcttat atactcattc acaaaacgcg
     1141 cttgctttgc cgttaactca ctcattctat cacctccaca attttatcta ataaggtttc
     1201 ataccataat cttacagatt gttctgaaca ctctaagaca ctactaatat cttta
//
LOCUS       DAPDIM010000151         1173 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000151 DAPDIM010000000
VERSION     DAPDIM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.161"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(253..1080)
                     /locus_tag="RFE25_002843"
     CDS             complement(253..1080)
                     /locus_tag="RFE25_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDU2817821.1"
                     /translation="MWKWEAENDAKGVVVIAHNILEHTGRYAYVITMLRRNGYHVIMG
                     DLPGQGQTSRANKGQIENFQTYHESLLDWLKIANEYKIPTYVLGVGLGGLILLNLLEK
                     VELPIEGMMLISPMLELQKNGKNRKDKLVSNIGKISKDTRFNVGVEPKDLTRNLEIVE
                     ETVNDGLMLKKATYHWYNTINETMKDTMAHIHDIQPMPTLLMYGTKDLIVDTRAIDEF
                     KEKYQTPELYFKAWQGFYHEVHNEPERDEVMRYILTFLNNSVNTMGFIVEDDEIVEI"
     gene            complement(1083..1172)
                     /locus_tag="RFE25_002844"
     CDS             complement(1083..1172)
                     /locus_tag="RFE25_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016169059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817822.1"
                     /translation="MDNNNTINRNLHSEFAIIMLLKINEKGAV"
BASE COUNT          389 a          215 c          132 g          437 t
ORIGIN      
        1 aaaagatacg cattgaattt ttattacata taactctcat gaaaattgat taaactaaat
       61 taattagtta gccttaaatt taacaaatta aatcaaaccg aatgaggcta aattggttat
      121 ttttcaagat atgatttgta taaatcaaaa catttcttac aaatcaaatg tgtataaaat
      181 gtgatataca ttctcaacct taaaaaagta aaaaaaaaag atgagcatct actgtctcat
      241 ctttttagaa tattaaattt ctacaatttc gtcatcttca acaataaagc ccattgtatt
      301 gacgctgtta tttaagaaag tcagaatata acgcattact tcatcacgtt ctggctcatt
      361 gtgaacctcg tggtaaaaac cttgccaagc tttaaaatat aattcaggtg tttgatattt
      421 ttctttaaac tcatcaattg ccctagtatc aacaattaaa tccttcgttc catacattaa
      481 tagcgttggc attggttgaa tgtcatgaat atgagccatc gtatctttca tcgtctcatt
      541 aattgtatta taccaatgat acgttgcttt ttttaacatt aaaccatcgt taactgtttc
      601 ttcaacaatt tctaaattac gtgttaaatc ttttggttct acaccaacat taaaacgtgt
      661 gtcttttgaa attttaccta tatttgaaac aagtttatct ttacgatttt ttccattctt
      721 ttgaagttct agcataggag aaattaacat catcccctcg attggcaatt ctactttttc
      781 aagtaaattt aataaaatca aaccgccaag tcctacccct aatacataag taggaatttt
      841 atattcatta gctatcttta accaatctag caaactttcg tgatacgttt gaaagttttc
      901 aatttgtcct ttattagctc ttgaagtttg accttgacca ggcaaatctc ccataatcac
      961 atgatagcca tttcttctta acatcgtaat aacatatgca tatcttcccg tatgttctaa
     1021 tatattatga gcaataacaa cgacgccttt cgcatcattt tcagcttccc acttccacat
     1081 tattatactg cccctttttc attaatcttc aataacataa ttatagcaaa ttcactatgt
     1141 agatttctat ttatagtatt attgttgtcc ata
//
LOCUS       DAPDIM010000152         1160 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000152 DAPDIM010000000
VERSION     DAPDIM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1160
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.162"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..398)
                     /gene="sarU"
                     /locus_tag="RFE25_002845"
     CDS             complement(<1..398)
                     /gene="sarU"
                     /locus_tag="RFE25_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarU"
                     /protein_id="HDU2817823.1"
                     /translation="MDYQTFEKVNKFINVEAYIFFLTQELKQQYKLSLKELLILAYFY
                     YKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRK
                     KIACVINELDKIIKGFNKERDYIKYQWAPK"
     gene            722..1078
                     /gene="sarT"
                     /locus_tag="RFE25_002846"
     CDS             722..1078
                     /gene="sarT"
                     /locus_tag="RFE25_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarT"
                     /protein_id="HDU2817824.1"
                     /translation="MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLD
                     VFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKKGYLNKCRDPHDSRNVIIVVSVKQ
                     HNYIKNLLSEININET"
BASE COUNT          441 a          131 c          150 g          438 t
ORIGIN      
        1 tattttggag cccattgata ttttatgtag tctctttcct tattaaatcc tttaattatt
       61 ttatctaact cattaataac acaagcaatc tttttacgtt gtattggagt aactgaaaca
      121 aaaatacggc gttcatctgc ttcgtttcta gacttattta taaatccttt tttagatagt
      181 gacttaatgt tctttacaac atcagattgt ttgtaaagta tgtcaccaat gatttctttt
      241 agtgaaatac tgtgttcatt tttgtaataa aaatatgcta atatcaacaa ttcttttaat
      301 gataatttat attgttgctt taactcttga gtgagaaaaa atatgtacgc ttctacattt
      361 atgaatttat tgaccttttc gaaagtttga tagtccacct tacattctcc tactattttc
      421 tgatgtccca atactttata ttatttaaag taatataaaa gcaatctctt ttgaagacat
      481 gttaacctaa atatttttat atataatata tataaaatat aaataactaa aaatcacgga
      541 ataacaaatg acaaattcat ttattatcca aaaacaaaaa caattgaaca aaatcaaaat
      601 atagtgttat gattcatttg tgtttatagc tagcaccaca aactaaatat atttggagtt
      661 attactagtt aaagacaaat attatttgac gtgacaatta aaagtaaggg atgaagactt
      721 gatgaatgat ttgaaaagca agagcaatat taaattaatg aaaagagtat taactacata
      781 tgagctgcgt aaatatttaa aaaaatattt ttgtcttaca ttagataatt atttagtatt
      841 agcatattta gatgtattta aaaatgatga aggtaaatat tttatgagag acattataag
      901 ttatatcggt atagaccaat ctagaattgt taaaagcgta aaagaattat caaaaaaggg
      961 ttacttgaat aaatgtagag acccacatga tagtagaaat gtaatcattg ttgtttctgt
     1021 aaaacaacac aattatatta aaaatctttt gagtgaaata aatattaatg aaacataaag
     1081 tatgtttcga gattttaata tcttggtgca gttaaatgta tttttaaatg cgttaaggta
     1141 ttttttattt tagaaattca
//
LOCUS       DAPDIM010000153         1159 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000153 DAPDIM010000000
VERSION     DAPDIM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.163"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(81..305)
                     /locus_tag="RFE25_002847"
     CDS             complement(81..305)
                     /locus_tag="RFE25_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HDU2817825.1"
                     /translation="MCFDYSALIGRIIEKYGNRYAFAYAIGLSERSLSLKLNDKIGWR
                     DSEIAKACELLSIPREEIQVYFFNYKVQNN"
     gene            467..847
                     /locus_tag="RFE25_002848"
     CDS             467..847
                     /locus_tag="RFE25_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDU2817826.1"
                     /translation="MNSTTSNRIKQAMKSSNLKQIDIVNKAKSMEKETGIKLSKTDLS
                     QYVNGKVTPGQKKLYVLAKILNVSEAWLLGYDVESKRIDDKERDKFNQHQETIAGHAN
                     KDEFTPEEWEEIENFMQWVRDRKK"
     gene            869..>1159
                     /locus_tag="RFE25_002849"
     CDS             869..>1159
                     /locus_tag="RFE25_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001558059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDU2817827.1"
                     /translation="MGKYEELLMKCEVEVKETQRVPRGFDGWYQEGEIFIRPSLSERN
                     KLEVLYEELAHHKLTYGNILDQSKFNNRKFENYARRHGFISAVPLREIVEAYN"
BASE COUNT          433 a          178 c          192 g          356 t
ORIGIN      
        1 atttctaact tctttcgcta taatttcttt caactcttct ttggttaacg tgatttgttc
       61 catagtgttc ctcctttagt tcaattattt tgaactttat aattaaaaaa atatacttgt
      121 atttcttctc tgggtataga taataattca caagctttag ctatttcgga atctctccaa
      181 ccaattttat catttaattt taaagataaa cttcgttctg ataagcctat cgcgtatgca
      241 aaagcatatc tattaccata cttttcaatt atacgaccta ttaaagctga ataatcaaaa
      301 cacatcatgt cacctctttc tgagttcaat atttttgaac tacatacacc ttaacacgtt
      361 taaaaaatca atgcaataca aaagttcaat atttttgaat ttttctattg aacttttgtt
      421 caacggagct tatactataa ctatattaat ggaggaggaa aattcattga actctacaac
      481 tagcaacaga atcaaacaag ctatgaagtc atcgaattta aaacaaatag atatagtaaa
      541 caaagctaaa agcatggaaa aagaaactgg tatcaaatta tcaaaaactg atttaagtca
      601 atatgttaat ggtaaagtga cgccgggtca gaagaaatta tatgttttag ctaaaatatt
      661 gaatgttagc gaagcttggt tgttgggata cgacgtagaa agtaaaagaa ttgatgataa
      721 agaaagagat aaatttaatc agcatcaaga aactatagct ggtcatgcaa ataaagatga
      781 atttactcct gaagaatggg aagaaatcga aaactttatg caatgggtta gagatagaaa
      841 gaaataagac accaaagggg tttggctcat gggaaaatac gaagaattgc ttatgaaatg
      901 tgaagttgaa gtgaaagaaa cacaaagagt acctcgagga ttcgatggtt ggtatcaaga
      961 aggagaaatt tttattagac cttccctatc cgaaaggaac aaattagaag tattatatga
     1021 agaacttgcc caccacaagt tgacgtatgg caacatttta gatcaatcga agttcaacaa
     1081 tcgcaagttc gaaaattacg cacgtagaca cggctttatc tcagctgtac cgctacgcga
     1141 aattgtagaa gcttataat
//
LOCUS       DAPDIM010000154         1126 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000154 DAPDIM010000000
VERSION     DAPDIM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1126
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.164"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            86..994
                     /locus_tag="RFE25_002850"
     CDS             86..994
                     /locus_tag="RFE25_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDU2817828.1"
                     /translation="MKKLLLPLIIMLLVLAACGNQGEKNNKAETKSYKMDDGKTVDIP
                     KDPKRIAVVAPTYAGGLKKLGANIVAVNQQVDQSKVLKDKFKGVTKIGDGDVEKVAKE
                     KPDLIIVYSTDKDIKKYQKVAPTVVVDYNKHKYLEQQEMLGKIVGKEDKVKAWKKDWE
                     ETTAKDGKEIKKAIGQDATVSLFDEFDKKLYTYGDNWGRGGEVLYQAFGLKMQPEQQK
                     LTAKAGWAEVKQEEIEKYAGDYIVSTSEGKPTPGYESTNMWKNLKATKEGHIVKVDAG
                     TYWYNDPYTLDFMRKDLKEKLIKAAK"
BASE COUNT          460 a          127 c          219 g          320 t
ORIGIN      
        1 ataaatagca ctagctattg taaatgtata tgcaatcttg tataattttg gaataattga
       61 taatcatttt caataggagg aaattatgaa aaaactatta ttaccattaa taattatgtt
      121 attagtgtta gctgcgtgtg ggaaccaagg tgaaaaaaat aacaaagctg aaactaaatc
      181 ttataaaatg gacgatggca aaacggtaga tattccgaaa gaccctaaac gcattgcagt
      241 agttgcgcca acatatgctg gtggacttaa aaaattaggt gcaaacattg tagctgtaaa
      301 tcaacaagtc gatcaaagca aagtattaaa agataaattt aaaggtgtta caaaaattgg
      361 tgatggcgat gtagaaaaag ttgctaaaga aaagccagat ttaattattg tatactctac
      421 tgacaaagat attaaaaaat atcaaaaagt agcaccaaca gtagttgttg actataataa
      481 gcataaatat ttagaacaac aagaaatgtt agggaaaatt gttggtaaag aagataaagt
      541 aaaagcttgg aagaaagatt gggaagaaac aactgctaaa gacggtaaag aaattaaaaa
      601 agcaattgga caagatgcaa cagtgtcatt gtttgatgaa tttgataaaa aattatacac
      661 ttacggcgat aactggggtc gtggtggaga agtattatat caagcatttg gtttgaaaat
      721 gcaaccagaa caacaaaagt taactgcaaa agcaggttgg gctgaagtga aacaagaaga
      781 aattgaaaaa tatgctggtg attacattgt gagtacaagt gaaggtaaac ctacaccagg
      841 atatgaatca acaaacatgt ggaagaattt gaaagctact aaagaaggac atattgttaa
      901 agttgatgct ggtacatact ggtacaacga tccttataca ttagatttca tgcgtaaaga
      961 tttaaaagaa aaattaatta aagctgcaaa ataattcagc tatataagtt agtgaaatga
     1021 gagtctgaaa catatcatct tttgatattg tattaggctc ttatttttat agctagaaag
     1081 ttagatattt gtattttttt aaataataag tgccgttgtt atcgtt
//
LOCUS       DAPDIM010000155         1102 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000155 DAPDIM010000000
VERSION     DAPDIM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1102
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.165"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            60..1019
                     /gene="hyl"
                     /locus_tag="RFE25_002851"
     CDS             60..1019
                     /gene="hyl"
                     /locus_tag="RFE25_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hemolysin"
                     /protein_id="HDU2817829.1"
                     /translation="MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNT
                     TVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKS
                     GLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGG
                     LIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYG
                     NQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYE
                     RVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN"
BASE COUNT          421 a          164 c          197 g          320 t
ORIGIN      
        1 aattgacata ttgattattg tttcctcaaa tcgttaaaaa aaatagaagg atgatgaaaa
       61 tgaaaacacg tatagtcagc tcagtaacaa caacactatt gctaggttcc atattaatga
      121 atcctgtcgc taatgccgca gattctgata ttaatattaa aaccggtact acagatattg
      181 gaagcaatac tacagtaaaa acaggtgatt tagtcactta tgataaagaa aatggcatgc
      241 acaaaaaagt attttatagt tttatcgatg ataaaaatca caataaaaaa ctgctagtta
      301 ttagaacgaa aggtaccatt gctggtcaat atagagttta tagcgaagaa ggtgctaaca
      361 aaagtggttt agcctggcct tcagccttta aggtacagtt gcaactacct gataatgaag
      421 tagctcaaat atctgattac tatccaagaa attcgattga tacaaaagag tatatgagta
      481 ctttaactta tggattcaac ggtaatgtta ctggtgatga tacaggaaaa attggcggcc
      541 ttattggtgc aaatgtttcg attggtcata cactgaaata tgttcaacct gatttcaaaa
      601 caattttaga gagcccaact gataaaaaag taggctggaa agtgatattt aacaatatgg
      661 tgaatcaaaa ttggggacca tatgatagag attcttggaa cccggtatat ggcaatcaac
      721 ttttcatgaa aactagaaat ggttctatga aagcagcaga gaacttcctt gatcctaaca
      781 aagcaagttc tctattatct tcagggtttt caccagactt cgctacagtt attactatgg
      841 atagaaaagc atccaaacaa caaacaaata tagatgtaat atacgaacga gttcgtgatg
      901 actaccaatt gcattggact tcaacaaatt ggaaaggtac caatactaaa gataaatgga
      961 cagatcgttc ttcagaaaga tataaaatcg attgggaaaa agaagaaatg acaaattaat
     1021 gtaaattatt tgttcatgta caaataaata taatttataa ctttagccga taacttcaga
     1081 aatgatgttt ttcggctaat tt
//
LOCUS       DAPDIM010000156         1045 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000156 DAPDIM010000000
VERSION     DAPDIM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.166"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(648..>1045)
                     /locus_tag="RFE25_002852"
     CDS             complement(648..>1045)
                     /locus_tag="RFE25_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDU2817830.1"
                     /translation="YFIKQIRAYMDGKIPVATVSNESSASSNTVKPVASAWKRNKYGT
                     YYMEESARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWE
                     GQRYYLPIRTWNGSAPPNQILGDLWGEIS"
BASE COUNT          322 a          221 c          183 g          319 t
ORIGIN      
        1 aaaaacaacc acactcctaa attaataggt ggtgtggttt tgttggttgt gtggtaaaaa
       61 ataaccgcat cggttaagat acggttatct agcaagtacc acgtacttac gaatacgttt
      121 agaatctctt cggcaacctt gctatagaca gtctatgctg ttactaaatt aaaccaccac
      181 acaaacctac tcccgttcag gaacacagag ctttgtcgct cgtcagcaac gtcatatgaa
      241 ttctcagttc atgttgtggc gacactttaa acagtctgtg ccagtagcga ccgagtcatt
      301 tcaagaatga ccatttcaca tttatattat aacataaaaa ccacccagca actagtatgg
      361 gtggtttaaa tatgcagtca gcttcttact actttacgca agtaagtcct ctgcatagcc
      421 ggattggcta ccggaaatgt ggttttaagc cagattggtt actggtaatg taattacatt
      481 ataacataaa aaataggcaa gtaccgtagt acctgcctgt tatctacatt taaatcttga
      541 gagaaatgtt aaaaagttct agtaaaataa tagcacattt tatctttaaa tgtaaataga
      601 aagcaggtat gtaacgcacc tgcttaaata gacatgacta tgtcattcta actgatttct
      661 ccccataagt cacctaatat ctgattaggt ggggcagaac cattccatgt tctaataggc
      721 aagtaataac gttgcccctc ccatgtatat cctacccaaa catgaccatc ttgtaacatc
      781 acttctgtat aatcacaata tccaccaggt tggaactgat aacccactgg acaagataag
      841 aatggcccca cttttcttac tgtgattggt tgattgccgt ttgtgaatct agcactttct
      901 tccatgtagt aagtaccata tttattacgt ttccatgcac ttgcaactgg tttaactgta
      961 ttacttgaag cgcttgactc attagagaca gtggcaaccg gtattttacc atccatgtac
     1021 gccctaatct gcttgataaa gtagt
//
LOCUS       DAPDIM010000157         1027 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000157 DAPDIM010000000
VERSION     DAPDIM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.167"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            53..430
                     /locus_tag="RFE25_002853"
     CDS             53..430
                     /locus_tag="RFE25_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2977 domain-containing protein"
                     /protein_id="HDU2817831.1"
                     /translation="MKITVNDKNEVIGFVNTGGLRNSLDVDDNNVPIKFKEEFEPRKF
                     VFTNGEIKYNSNFEKEDVPNASNQQSASDLSDEELRGMVASMQMQMTQVNMLTMQLTQ
                     QNAMLTQQLTELKTNKTNTEGDV"
     gene            434..607
                     /locus_tag="RFE25_002854"
     CDS             434..607
                     /locus_tag="RFE25_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDU2817832.1"
                     /translation="MKMIYPTFKDIKTFYVWGCYKNEQIKWYVDMGVIDKEEYALITG
                     EKYPEAKDEKSQV"
     gene            648..947
                     /locus_tag="RFE25_002855"
     CDS             648..947
                     /locus_tag="RFE25_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2951 domain-containing protein"
                     /protein_id="HDU2817833.1"
                     /translation="MFGFTKRHEHEWRIRRLEENDKTMLSTLNEIKLGQKTQEQVNIK
                     LDKTLDAIQRERQIDEKNKKENDKNIRDMKMWILGLIGTIFSTIVIALLRTIFGI"
BASE COUNT          401 a          138 c          221 g          267 t
ORIGIN      
        1 ctggagcgaa tgccaacaaa gttactataa ctaaaattat ggggtggaaa taatgaaaat
       61 cacagtaaac gataaaaacg aagttatcgg attcgttaat actggcggtt tacgcaatag
      121 tttagatgta gatgataaca atgtgcctat taaatttaaa gaagagttcg aacctagaaa
      181 gtttgttttc actaacggcg aaattaaata caatagcaat ttcgaaaaag aagacgtacc
      241 gaatgcatca aaccaacaaa gtgcgtcaga tttaagtgat gaggaacttc gcggaatggt
      301 tgcaagtatg caaatgcaga tgacgcaagt gaacatgttg acaatgcaat tgacgcaaca
      361 aaacgctatg ttaacacaac agttgaccga actgaaaact aacaaaacaa atactgaggg
      421 ggacgtttaa atgatgaaga tgatttatcc aacttttaaa gacattaaaa ctttttatgt
      481 gtggggttgc tataaaaatg agcaaattaa gtggtacgta gacatgggtg taatcgacaa
      541 agaagaatat gcattgatca ctggtgaaaa atatccagag gcaaaagatg aaaagtcaca
      601 ggtgtaatgc ttgaggcttt ttaatttaac acaaagtagg tggcgtaatg tttggattta
      661 ccaaacggca cgaacatgaa tggcgaatta gaagattaga agagaatgat aaaacaatgc
      721 ttagcactct caatgagatt aaattaggtc aaaaaactca agagcaagtt aacattaaat
      781 tagataaaac tttagatgct atccagaggg aaagacagat agacgaaaaa aataagaaag
      841 aaaacgacaa aaatatacgc gatatgaaaa tgtggattct cggtttgata gggactatct
      901 tcagtacgat tgtcatagct ttactaagaa ctatttttgg tatttaaagg aggtgattac
      961 catgcttaaa gggattttag gatatagctt ctgggcgtgc ttctggtttg gtaaatgtaa
     1021 ataacag
//
LOCUS       DAPDIM010000158          867 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000158 DAPDIM010000000
VERSION     DAPDIM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.168"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            81..>867
                     /locus_tag="RFE25_002856"
     CDS             81..>867
                     /locus_tag="RFE25_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDU2817834.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNI"
BASE COUNT          321 a          160 c          161 g          225 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatct
//
LOCUS       DAPDIM010000159          818 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000159 DAPDIM010000000
VERSION     DAPDIM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.169"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(114..509)
                     /locus_tag="RFE25_002857"
     CDS             complement(114..509)
                     /locus_tag="RFE25_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817835.1"
                     /translation="MEANLKGVKKLVYKGVEYSKVFAGNTKVWSKPPSFVIKPLPKNK
                     YPDSIEDSTAKWTINGVEPNKNYQVTIENVRSGIMRVSQTNLGSSDLGISGVNSGVAS
                     KSINFSNPSGILYVTISDVYSGSPTLTIE"
     gene            complement(514..>818)
                     /locus_tag="RFE25_002858"
     CDS             complement(514..>818)
                     /locus_tag="RFE25_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDU2817836.1"
                     /translation="TEDFERFKQTLNSLYADKNHSHTIKQIEGLENALSRKSDINHNH
                     DERYVLSSQAFTKQQADNLYQLKGASQPTVKIWTGTENEYNYIYQKDPNTLYLIKG"
BASE COUNT          236 a          154 c          107 g          321 t
ORIGIN      
        1 ccaactaaac ctgttaatac tgctttattt ttaaatctca atttccagtt aatatccatt
       61 tgtttgctcc ttttacccaa aataaaaaac gactaaaaat tagtcgttta aaattattcg
      121 atggtcaaag tcggagatcc tgaataaaca tcacttatag tgacatacaa aatcccggaa
      181 ggattactaa agttaatgct tttacttgca actccactat tgactcctga tattcctaaa
      241 tcacttgatc ctaaattagt ttgcgaaacc ctcattatac cgctgcgtac attttctatt
      301 gtcacctgat aatttttgtt aggttcaact ccatttattg tccattttgc tgttgaatct
      361 tctatgctat ccggatattt atttttaggt aagggtttaa ttacaaaaga cggcggttta
      421 gaccaaactt ttgtattacc tgcaaatact ttagagtatt caaccccttt gtataccaat
      481 ttctttacac cttttaaatt agcttccatg tcatcaccct ttaattaaat ataacgtatt
      541 cgggtctttt tgatatatat agttatattc attttctgtt cctgtccaaa ttttaaccgt
      601 cggttgagat gcgcctttta gttgatataa attatccgct tgttgtttag taaaagcttg
      661 agacgacaaa acatacctct cgtcatgatt atgatttatg tctgattttc ttgataaagc
      721 attttctaat ccttcaatct gtttgattgt atgactatga tttttatctg catacaaact
      781 gtttaatgtt tgtttgaacc tctcaaaatc ttctgtac
//
LOCUS       DAPDIM010000160          807 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000160 DAPDIM010000000
VERSION     DAPDIM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.170"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..685
                     /locus_tag="RFE25_002859"
     CDS             <1..685
                     /locus_tag="RFE25_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDU2817837.1"
                     /translation="SRSAQIKDTFNQTLKLYPTKNLEDFYDKEGFRDQEFEKGDKGNW
                     IVDSEMVIELKDKKMESRSMVLYINRNTRTTKGNFIVRELWEDSKGYAQSKDTKYPVK
                     MEHNRIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYNPNVPSYSAKYQ
                     LKNDDYNVKQLRKRYNIPTNKAPKLLLKGDGDLKGSSIGSKNLEFTFVENKEENIYFS
                     DSINFKPTE"
BASE COUNT          339 a           97 c          135 g          236 t
ORIGIN      
        1 tagtcgaagc gcccaaatta aagacacatt taatcaaaca ttaaaattat atccaaccaa
       61 aaatcttgaa gacttttatg ataaggaagg ctttcgagat caagagtttg aaaagggcga
      121 caaaggcaat tggattgttg attctgagat ggtaattgag ctgaaggata aaaaaatgga
      181 atctagaagt atggtgctct atataaatcg taatactaga acaacgaaag gtaattttat
      241 tgttagagaa ttgtgggaag atagtaaagg gtatgcacaa agtaaagata caaaatatcc
      301 agtgaaaatg gaacataatc gaattatccc aacgaaaccg atagctgatg ataaattaag
      361 aaaagaaata gaaaacttta aattctttgt acaatacggt gactttaaag atattaatga
      421 ttataaagat ggtgacattt catataatcc taatgttcca agttattccg caaaatatca
      481 attgaaaaac gatgattaca atgtgaagca acttcgaaaa agatataata ttccaaccaa
      541 caaagctccg aaactattat tgaaaggtga tggtgattta aaaggttcat caataggatc
      601 aaaaaatcta gaatttacct ttgtagaaaa taaagaagag aacatttatt tttctgatag
      661 tattaatttc aaacctactg aatagggtta atagaagttt ggaatgaaaa ttccataaag
      721 cactaggtaa aagattataa cgataactct taaaattaat aataaatcac agaaacttta
      781 tcttttgatt taattgtttt ataattc
//
LOCUS       DAPDIM010000161          764 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000161 DAPDIM010000000
VERSION     DAPDIM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..764
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.171"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..>764)
                     /locus_tag="RFE25_002860"
     rRNA            complement(<1..>764)
                     /locus_tag="RFE25_002860"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          175 a          231 c          148 g          210 t
ORIGIN      
        1 gctcagcctt aacgagtacc ggatttgcct aatactcagc cttactgctt agacgtgcaa
       61 tccaatcgca cgcttcgcct atcctactgc gtccccccat cgattaaaac gattataggt
      121 ggtacaggaa tatcaacctg ttatccatcg cctacgcctg tcggcctcag cttaggaccc
      181 gactaaccca gagcggacga gccttcctct ggaaacctta gtcaatcggt ggacgggatt
      241 ctcacccgtc tttcgctact cacaccggca ttctcacttc taagcgctcc acatgtcctt
      301 acgatcatgc ttcaacgccc ttagaacgct ctcctaccat tgtccaaagg acaatccaca
      361 gcttcggtaa tatgtttagc cccggtacat tttcggcgca gtgtcactcg actagtgagc
      421 tattacgcac tctttaaatg atggctgctt ctaagccaac atcctagttg tctgggcaac
      481 gccacatcct tttccactta acatatattt tgggacctta gctggtggtc tgggctgttt
      541 ccctttcgaa cacggacctt atcacccatg ttctgactcc caagttaaat taattggcat
      601 tcggagtttg tctgaattcg gtaacccgag aggggcccct cgtccaaaca gtgctctacc
      661 tccaataatc atcacttgag gctagcccta aagctatttc ggagagaacc agctatctcc
      721 aggttcgatt ggaatttctc cgctaccctc agttcatccg ctca
//
LOCUS       DAPDIM010000162          756 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000162 DAPDIM010000000
VERSION     DAPDIM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..756
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.172"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
BASE COUNT          320 a          101 c           82 g          253 t
ORIGIN      
        1 tataataata tttttttaaa agaacaatta actaaatatc aaaaatgtat taactatcta
       61 ttaactaaaa aatagaataa ttttttaaca tcgttttgtt gttttgaatt ataaaaacta
      121 aagtaaaaat gttggatgtg aaagattgtt gatgagaatt ttgagatgta gataaatatc
      181 aaactagtct ataggtaaaa atttataatt aatttgaaaa gaatgtctca aataatgttt
      241 gaattagcag gtgtcatact aagtaatgtt aagtaaacat tttatacttt atcagaacaa
      301 aaaagacatg catcaacatg tcagtgaaac taatccatat tatcttaaca acgaaattga
      361 atcgaacctg aaaaacgtat ttacaaatcg caactactct atccaaggcg aaatcgcaaa
      421 atctgatccc cgaaataaca tatctcgaaa aaaattccat aattcaatca tcttcaataa
      481 ttaacaatac attactagtt ccaaatatac tcatacatac atgtttcatt gattgactgc
      541 atattgtcat aaataatagg ggaactaatc gctaataata ttgttaaaca caatacataa
      601 taaagtgaaa gattttaaat acatgaattg ttcaccattc cgccatatat tttcaattac
      661 ctaatttccg aataaatatt acaattttaa ttcaataatt aatatttaag accaaaataa
      721 tcctaaaaag tcaattttaa ttgcgtgata ttgagt
//
LOCUS       DAPDIM010000163          721 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000163 DAPDIM010000000
VERSION     DAPDIM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.173"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(115..510)
                     /locus_tag="RFE25_002861"
     CDS             complement(115..510)
                     /locus_tag="RFE25_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817838.1"
                     /translation="MEGNFKNVKKLIYEGEEYTKVYAGNIQVWKKPSSFVIKPLPKNK
                     YPDSIEESTAKWTINGVEPNKSYQVTIENVRSGIMRVSQTNLGSSDLGISGVNSGVAS
                     KNINFSNPSGMLYVTISDVYSGSPTLTIE"
     gene            complement(516..>721)
                     /locus_tag="RFE25_002862"
     CDS             complement(516..>721)
                     /locus_tag="RFE25_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDU2817839.1"
                     /translation="NDLYAPKNHNHDERYVLSSQAFTKQQADSLYQLKSASQPTVKIW
                     TGTENEYNYIYQKDPNTLYLIKG"
BASE COUNT          213 a          129 c           96 g          283 t
ORIGIN      
        1 ccaactaaac cagttagtac tgctttgttt ttgaatctca atttccagtt aatatccatt
       61 tgtttgctcc ttttatccaa aataaaaaaa cgactaaaaa ttagtcgttt aaaattattc
      121 aatggtcaat gtcggagatc ctgaataaac atcacttata gtgacataca acatccctga
      181 aggattacta aagttgatat ttttacttgc aactccgcta ttgactcctg atattcctaa
      241 atcacttgaa cctaaattag tttgcgaaac cctcattata ccgctacgta cattttctat
      301 tgtcacctga taacttttat taggttcaac tccatttatt gtccattttg ctgttgattc
      361 ttctatgcta tccggatatt tatttttagg taagggtttt attacaaaag atgaaggctt
      421 tttccatact tggatatttc cagcatatac ttttgtatat tcttcgcctt cgtaaataag
      481 tttctttaca tttttaaaat taccttccat aaaaatcacc ccttaattaa gtaaagtgta
      541 ttagggtctt tttgatatat atagttatat tcattttctg ttcctgtcca aattttaacc
      601 gtcggttgag atgcgctttt tagttgatat aaactatccg cttgttgttt agtaaaagct
      661 tgagatgaca aaacataccg ctcgtcatga ttatgatttt ttggagcata taaatcattt
      721 a
//
LOCUS       DAPDIM010000164          714 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000164 DAPDIM010000000
VERSION     DAPDIM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..714
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.174"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..703
                     /locus_tag="RFE25_002863"
     CDS             <1..703
                     /locus_tag="RFE25_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDU2817840.1"
                     /translation="SQKNIVYITPSHQFPTGYVMDLKKRTQLIQWAQEKEERFIIEDD
                     YDSEFRYFGKPIPAIQGLYSRGEKVIYISTFSKSIFPSCRVAYMVLPYSIMKKYHSQN
                     HIEGNTVPVHMQNLIATFISSGGFERHLNKMRRIYRRKLTYILKRLKPYKEQLDIQGA
                     ETGMHFTITVKNGLTLQECLDRANKVKLKLQVYNFDDDQDYKKTPKFILGFGGIDDDA
                     LKPHVDALIKSLIIK"
BASE COUNT          275 a          108 c          112 g          219 t
ORIGIN      
        1 atcacaaaaa aatatagtat atataacgcc ttcccatcaa tttccaactg gatatgtgat
       61 ggacttaaaa aaacgaactc aattaataca atgggctcaa gaaaaagaag aacgatttat
      121 tatagaagat gattatgatt ccgagtttag atatttcggc aaacccattc cagcaattca
      181 aggtctatat tcaagaggag aaaaagtgat ttatatcagt acattttcaa agtctatttt
      241 tcctagctgt cgagttgcat atatggtgtt accctattct ataatgaaaa aatatcattc
      301 tcaaaatcac attgaaggca acactgtacc tgttcatatg caaaacctta ttgcaacgtt
      361 tatatcttcc ggtggttttg aaaggcattt aaataaaatg agacgaattt atcgtagaaa
      421 actaacctat attttaaaaa gattgaaacc ttacaaagag cagcttgata ttcaaggtgc
      481 tgaaacgggt atgcatttta caattacagt aaaaaatgga ttaacattac aagagtgtct
      541 tgatagagca aacaaagtaa agttaaaatt acaagtttat aattttgatg atgatcaaga
      601 ctataagaaa acccctaaat ttatattagg ctttggcggt atagacgatg atgctttaaa
      661 accgcatgta gacgctctaa taaaatcatt aattataaag taacacttct ttga
//
LOCUS       DAPDIM010000165          700 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000165 DAPDIM010000000
VERSION     DAPDIM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.175"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..698
                     /locus_tag="RFE25_002864"
     CDS             <1..698
                     /locus_tag="RFE25_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDU2817841.1"
                     /translation="DFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQH
                     MGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKIT
                     TFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPN
                     ISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKS
                     PKNYRYTKGQIYL"
BASE COUNT          254 a          104 c           91 g          251 t
ORIGIN      
        1 tagactttat taattgtaaa aaattgagta aattatcttt acattctaaa ttagtcttaa
       61 ctacaactag tatcctaata attataggag ctattacatt ctttttatta gaacagttta
      121 atactatgca acatatggga ctagttgaaa aaatcggaaa ttcttttttc caatcagtaa
      181 caacacgaac agcgggtttt aacagtattg atatagcaag cattaacaaa tctaccgcct
      241 taatgttaat gttacttatg tttattggtg gtgcccctct cagtgcagct ggaggaatta
      301 aaataactac ttttgcagtg gcgtttatat ttgttttaaa ttatatacgt aaagaaaata
      361 atgtttcagt attcaataaa gaaatatctg acaaacatat aaaactatct attgttacca
      421 ttaatatctc atttctattt atcagtatca ttacttttat attatcgata attaatccga
      481 acatatcatt aatcaagtta ttattcgaag tggtttctgc attcggaaca gtcgggttaa
      541 gtatgaacct taccacagaa tatcatggta ttactaaaat aattattata ttcgttatgc
      601 tttgcggtaa agtaggacta ttaactttat taagaacatt tataccacca aaaagtccta
      661 aaaattaccg ctacactaaa ggacaaattt atctataaaa
//
LOCUS       DAPDIM010000166          685 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000166 DAPDIM010000000
VERSION     DAPDIM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.176"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..95
                     /locus_tag="RFE25_002865"
     CDS             <1..95
                     /locus_tag="RFE25_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDU2817842.1"
                     /translation="KFGSITIDNNNSIYRIIFHIEKGRIRYEKL"
     gene            82..381
                     /locus_tag="RFE25_002866"
     CDS             82..381
                     /locus_tag="RFE25_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGE"
                     /protein_id="HDU2817843.1"
                     /translation="MKSYKCKGSFLIDSMAGFLLIGLITLLLIPMMNQMQASINHKLQ
                     SIDASKVILTTVSKINKEELKKGVTIGKYDIKQSDQQICAISKNTTSYQKTCIQY"
     gene            299..>685
                     /locus_tag="RFE25_002867"
     CDS             299..>685
                     /locus_tag="RFE25_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDU2817844.1"
                     /translation="MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVI
                     SIILLIVPDLIRLSKTFLIESRELTTVDFEFFSRDILEDFKGVDKNDIEIRQQRIILH
                     KGEEMIEYKLINNKIIKVVNDRGNITM"
BASE COUNT          282 a           74 c          111 g          218 t
ORIGIN      
        1 ataaatttgg tagcataaca attgacaata acaattcaat ttatagaata atattccata
       61 ttgaaaaagg aagaattcgt tatgaaaagc tataagtgta aaggatcatt cttaatagat
      121 agtatggctg gatttttgct aattggattg attacattac tattgatacc aatgatgaat
      181 caaatgcaag cgagtataaa ccataaacta caatcaattg atgcttctaa agtaattttg
      241 acgactgtat ctaaaattaa taaagaagaa cttaagaagg gggtaactat agggaaatat
      301 gatattaagc aaagtgacca acaaatttgt gctatttcaa aaaataccac ttcttatcaa
      361 aagacatgta tacagtatta atgtcaaagc tttttcgctt attgaaatgt tagtagcgat
      421 gatggttata agtataattt tactaattgt tccagactta attagactta gcaaaacttt
      481 tctaattgaa agtagggaat taacaactgt agatttcgaa tttttctcaa gagatattct
      541 agaggatttt aaaggtgtag ataaaaacga tattgaaatt aggcaacagc gtatcatttt
      601 acataaaggt gaagaaatga tcgaatacaa attaataaat aataaaatta ttaaagttgt
      661 aaatgacaga ggaaatataa caatg
//
LOCUS       DAPDIM010000167          681 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000167 DAPDIM010000000
VERSION     DAPDIM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..681
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.177"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>681
                     /locus_tag="RFE25_002868"
     CDS             <1..>681
                     /locus_tag="RFE25_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817845.1"
                     /translation="TDDYGKAIESYEQSIDSVLSAVNTSRIIHITNATDAPEKTDIGT
                     LEKPGQDGVDDGSSFDESTYTSSKSGVLVVYVVDNNTARATWYPDDSNDEYTKYKIYG
                     TWYPFYKKNDGNLTKQFVEETSNNALNQAKQYVDDKFGTTSWQQHKMTEANGQSIQVN
                     LNNAQGDLGYLTAGNYYATRVPDLPGSVESYEGYLSVFVKDDTNKLFNFTPYNSKKIY
                     TRSITNGRL"
BASE COUNT          244 a          115 c          139 g          183 t
ORIGIN      
        1 acagatgatt acggtaaagc aattgaatcg tatgagcagt ccatagatag cgttttaagc
       61 gcagttaaca catctaggat tattcatatt actaatgcaa cagatgcgcc agaaaagacg
      121 gatataggca cgttagagaa gcctggacaa gatggtgttg atgacggttc ttcgttcgat
      181 gaatcaactt atacatcaag caaatctggt gtgttagttg tttatgttgt tgataataat
      241 actgctcgtg caacatggta cccagacgat tcaaacgatg agtacacaaa atacaaaatc
      301 tacggcacat ggtacccgtt ttataaaaag aatgatggaa acttaactaa gcaatttgtt
      361 gaagaaacgt ctaacaacgc tttaaatcaa gctaagcagt atgtagatga taaattcgga
      421 acaacgagct ggcaacaaca taagatgaca gaggcgaatg gtcaatcaat tcaagttaac
      481 ttaaataatg cgcaaggcga tttgggatat ttaactgctg gtaattacta tgcaacaaga
      541 gtgccggatt taccaggtag cgttgaaagt tatgagggtt atttatcggt attcgttaaa
      601 gatgatacaa acaagctatt taacttcaca ccttataact ctaaaaagat ttacacacga
      661 tcaatcacaa acggcagact t
//
LOCUS       DAPDIM010000168          677 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000168 DAPDIM010000000
VERSION     DAPDIM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.179"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>677
                     /locus_tag="RFE25_002869"
     CDS             <1..>677
                     /locus_tag="RFE25_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HDU2817846.1"
                     /translation="IIDTNISFYESDRGTGVLNFAVTKNNRPLSISSEHVKTSIVLKT
                     DDYNVDRGAYISDELTIVDAINGRLQYVIPNEFLKHSGKVHAQAFFTQNGSNNVVVER
                     QFSFNIENDLVSGFDGITKLVYIKSIQDTIEAVGKDFNQLKQNMADTQTLIAKVNDSA
                     TKGIQQIEIKQNEAIQAITATQTSATQAVTAEFDKIVEKEQAIFERVNEVEQQINGAD
                     LVKGNSTT"
BASE COUNT          254 a          103 c          130 g          190 t
ORIGIN      
        1 attattgaca caaacatcag tttctatgaa tcagatagag gaactggtgt tttaaatttt
       61 gcagtaacta agaataacag accgttatct ataagttctg aacatgttaa gacatctatc
      121 gtgttaaaaa ccgatgatta taacgtagat agaggcgctt atatttcaga cgaattaacg
      181 atagtagacg caattaatgg gcgtttgcag tatgtgatac cgaatgaatt tttaaaacat
      241 tcaggcaagg tgcatgctca ggcattcttt acacaaaacg ggagtaataa tgttgttgtt
      301 gaacgtcaat ttagcttcaa tattgaaaat gatttagtta gtgggtttga tggtataaca
      361 aagcttgttt atatcaaatc tattcaagat actatcgaag ctgtcggtaa agactttaac
      421 caattaaagc aaaatatggc tgatacacaa acgttaatag caaaagtgaa tgatagtgcg
      481 acaaaaggca ttcaacaaat cgaaatcaag caaaacgaag ctatacaagc tattactgcg
      541 acgcaaacta gtgcaacaca agctgttaca gctgaattcg ataaaatagt tgaaaaagag
      601 caagcgattt ttgaacgtgt taacgaagtt gaacaacaaa tcaatggcgc tgaccttgtt
      661 aaaggtaatt caacaac
//
LOCUS       DAPDIM010000169          677 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000169 DAPDIM010000000
VERSION     DAPDIM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.180"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..>677)
                     /locus_tag="RFE25_002870"
     CDS             complement(<1..>677)
                     /locus_tag="RFE25_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HDU2817847.1"
                     /translation="VIDTNISFYESDRGTGVLNFAVTKNNKPLSISKHNAMTSIVLKT
                     DNFDDEHGAYISDELTIVDAINGRMQYVIPNEFLKYTGRVHAQAYFTQNGSNNVIVER
                     QFNFNIQNDLISNFDGKTKLVYIKSIQDLTESVKEEVEDLKKSLSDTKSLVTEIDSRI
                     NQGIQRLEIKQNEAVQMITTTQDKAVQYINSEFQKIVDKEQAIFERVNEVEQQINGAD
                     LVKGNSTT"
BASE COUNT          191 a          125 c           97 g          264 t
ORIGIN      
        1 gttgttgaat tacctttaac aaggtcagcg ccattgattt gttgttcaac ttcgttaaca
       61 cgttcaaaaa tcgcttgctc tttatcaaca attttctgga actcgctatt tatatattga
      121 acggctttgt cttgtgttgt tgtaatcatc tgtaccgctt cattttgttt aatttctaat
      181 ctttgaatac cttgattaat acgactatca atttcagtaa ccaacgattt tgtatcactt
      241 aaacttttct ttaagtcctc aacttcttct ttaacacttt ctgttaagtc ctgaattgat
      301 ttgatataaa ctagctttgt tttaccgtca aaattactaa ttagatcatt ctggatattg
      361 aagttaaatt gacgttctac aattacgtta ttgctaccgt tttgagtaaa atatgcttgc
      421 gcatgtactc gaccagtgta ttttaaaaac tcgttaggga taacatattg cattcgtcca
      481 ttaattgcat caacaattgt aagttcatca ctaatataag cgccgtgttc atcgtcgaag
      541 ttatccgtct taagcacaat actagtcatc gcattatgtt tgctgattga taacggctta
      601 ttattcttag ttactgcaaa atttaaaaca ccagttcctc tatctgattc atagaaactg
      661 atgtttgtgt caataac
//
LOCUS       DAPDIM010000170          634 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000170 DAPDIM010000000
VERSION     DAPDIM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.181"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>634
                     /locus_tag="RFE25_002871"
     rRNA            <1..>634
                     /locus_tag="RFE25_002871"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          174 a          147 c          181 g          132 t
ORIGIN      
        1 cactgccgag aaaagcctct agatagaaaa taggtgcccg taccgcaaac cgacacaggt
       61 agtcaagatg agaattctaa ggtgagcgag cgaactctcg ttaaggaact cggcaaaatg
      121 accccgtaac ttcgggagaa ggggtgctct ttagggttaa cgcccagaag agccgcagtg
      181 aataggccca agcgactgtt tatcaaaaac acaggtctct gctaaaccgt aaggtgatgt
      241 ataggggctg acgcctgccc ggtgctggaa ggttaagagg agtggttagc ttctgcgaag
      301 ctacgaatcg aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa
      361 ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa cgatttgggc actgtctcaa
      421 cgagagactc ggtgaaatca tagtacctgt gaagatgcag gttacccgcg acaggacgga
      481 aagaccccgt ggagctttac tgtagcctga tattgaaatt cggcacagct tgtacaggat
      541 aggtaggagc ctttgaaacg tgagcgctag cttacgtgga ggcgctggtg ggatactacc
      601 ctagctgtgt tggctttcta acccgcacca ctta
//
LOCUS       DAPDIM010000171          629 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000171 DAPDIM010000000
VERSION     DAPDIM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.182"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(154..384)
                     /locus_tag="RFE25_002872"
     CDS             complement(154..384)
                     /locus_tag="RFE25_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817848.1"
                     /translation="MEFNDFQNFFGELSNQAEKEFGGDSDFFRDRINKLKEDAPENVS
                     YEIIYSIALYESLKAQQDMKILNTVKYLLNRD"
     gene            434..571
                     /locus_tag="RFE25_002873"
     CDS             434..571
                     /locus_tag="RFE25_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817849.1"
                     /translation="MVEVPPHIQQMLYEIQLKAGIPQKLMEMQGLINDETTKEEKKEN
                     E"
     gene            564..>629
                     /locus_tag="RFE25_002874"
     CDS             564..>629
                     /locus_tag="RFE25_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1270 family protein"
                     /protein_id="HDU2817850.1"
                     /translation="MSNIYKSYLVAVLCFTVLAIVL"
BASE COUNT          238 a          105 c           93 g          193 t
ORIGIN      
        1 aaatgaacac gttatacaaa acaaccttcc tcatcacaat ggcagttgcg acttggaagg
       61 tttggaagat tgagaaaaac acaagattta aacttagaaa ttttgattat ccaaaaatta
      121 ataatgctca gagcaaatca ttgttggata ttgctagtca cgatttaaaa gatatttaac
      181 tgtattcaaa attttcatat cttgttgagc ttttaagctt tcgtataaag ctattgaata
      241 aataatttcg taagatacgt tttcaggagc atcttctttc aacttattta ttctatctct
      301 aaaaaagtca ctgtcaccac cgaattcttt ttcggcttga ttactaagtt caccaaagaa
      361 attttgaaaa tcattaaatt ccatacttat cacctccttt cactaggaga taactaaatt
      421 atacacgaaa ggaatggtag aagtgccacc acacattcaa caaatgttat acgaaatcca
      481 gttaaaagct ggtatacctc aaaaattaat ggaaatgcaa ggtttgataa acgatgaaac
      541 aaccaaagag gagaaaaaag aaaatgagta acatttataa aagctaccta gtagcagtac
      601 tatgcttcac agtcttagca attgtgctt
//
LOCUS       DAPDIM010000172          623 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000172 DAPDIM010000000
VERSION     DAPDIM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.183"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..60
                     /locus_tag="RFE25_002875"
     CDS             <1..60
                     /locus_tag="RFE25_002875"
                     /inference="COORDINATES: protein motif:HMM:NF018593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1270 family protein"
                     /protein_id="HDU2817851.1"
                     /translation="AGFASIATFIFYKEYFYGE"
     gene            154..414
                     /locus_tag="RFE25_002876"
     CDS             154..414
                     /locus_tag="RFE25_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1108 family protein"
                     /protein_id="HDU2817852.1"
                     /translation="MYYEIGEIIRKNIHVNGFDFKLFILKGHMGISIQVKDMNNVPIK
                     HAYVVDENDLDMASDLFNQAIDEWIEENTDEQDRLINLVMKW"
     gene            424..>623
                     /locus_tag="RFE25_002877"
     CDS             424..>623
                     /locus_tag="RFE25_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2483 family protein"
                     /protein_id="HDU2817853.1"
                     /translation="MKQTVTYIIRHRDMPIYITNKPTDNNSDISYSTNKNRAREFNGM
                     EEASINMDYHKAIKKTVTETIE"
BASE COUNT          256 a           92 c          117 g          158 t
ORIGIN      
        1 gcgggattcg caagtatagc gacattcata ttttataagg aatactttta tggagaataa
       61 aaaaactgct acttgcgcca acaagtaaca gtgacaaacg attaacaaaa ttaattcgtg
      121 ttcaatataa aacgaaaaaa ggaggaagtc aagatgtatt acgaaatagg cgaaatcata
      181 cgcaaaaata ttcatgttaa cggattcgat tttaagctat tcattttaaa aggtcatatg
      241 ggcatatcaa tacaagttaa agatatgaac aacgtaccaa ttaaacatgc ttatgtcgta
      301 gatgagaatg acttagatat ggcatcagac ttattcaacc aagcaataga tgaatggatt
      361 gaagagaaca cagacgaaca ggacagacta attaacttag tcatgaaatg gtaggaggtc
      421 gctatgaagc agactgtaac ttacatcatt cgtcataggg atatgccaat ttatataact
      481 aacaaaccaa ctgataacaa ttcagatatt agttactcca caaataaaaa tagagctagg
      541 gagtttaacg gtatggaaga agcgagtatc aatatggatt atcacaaagc aatcaagaaa
      601 acagtgacag aaactattga gta
//
LOCUS       DAPDIM010000173          618 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000173 DAPDIM010000000
VERSION     DAPDIM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.184"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..>618)
                     /locus_tag="RFE25_002878"
     rRNA            complement(<1..>618)
                     /locus_tag="RFE25_002878"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          134 a          184 c          130 g          170 t
ORIGIN      
        1 aaggatgtca agatttggta aggttcttcg cgttgcttcg aattaaacca catgctccac
       61 cgcttgtgcg ggtccccgtc aattcctttg agtttcaacc ttgcggtcgt actccccagg
      121 cggagtgctt aatgcgttag ctgcagcact aaggggcgga aaccccctaa cacttagcac
      181 tcatcgttta cggcgtggac taccagggta tctaatcctg tttgatcccc acgctttcgc
      241 acatcagcgt cagttacaga ccagaaagtc gccttcgcca ctggtgttcc tccatatctc
      301 tgcgcatttc accgctacac atggaattcc actttcctct tctgcactca agttttccag
      361 tttccaatga ccctccacgg ttgagccgtg ggctttcaca tcagacttaa aaaaccgcct
      421 acgcgcgctt tacgcccaat aattccggat aacgcttgcc acctacgtat taccgcggct
      481 gctggcacgt agttagccgt ggctttctga ttaggtaccg tcaagatgtg cacagttact
      541 tacacatatg ttcttcccta ataacagagt tttacgatcc gaagaccttc atcactcacg
      601 cggcgttgct ccgtcagg
//
LOCUS       DAPDIM010000174          610 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000174 DAPDIM010000000
VERSION     DAPDIM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.185"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            141..401
                     /locus_tag="RFE25_002879"
     CDS             141..401
                     /locus_tag="RFE25_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1108 family protein"
                     /protein_id="HDU2817854.1"
                     /translation="MYYEIGDVCQKVINVDGFDFKLAVKKKDHSILVNILDLEDKFID
                     GINITNENDLYTALDILNQSIYEWIEENTDEQDRLINLVMKW"
     gene            411..>610
                     /locus_tag="RFE25_002880"
     CDS             411..>610
                     /locus_tag="RFE25_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2483 family protein"
                     /protein_id="HDU2817855.1"
                     /translation="MKQTVTYLIKHKDENLFITNRPTEVNDTVKYSTDMRDAREFDGL
                     DKTVIDMSKHKAIKKTVTETIE"
BASE COUNT          255 a           89 c          117 g          149 t
ORIGIN      
        1 aagtatcgca acattcatgt actacaaaga atgctttttc aaagaataaa aaaactgcta
       61 cttgttggag caagtaacag tatcaagcac ttaagaaaaa tttcaagtta aatataaaac
      121 gaaaaacgga ggaagtcaag atgtattacg aaataggcga tgtatgtcag aaggtaatta
      181 atgtagacgg atttgatttt aaattagcag ttaagaagaa ggaccacagc attctggtga
      241 atatcttaga tttagaagat aagtttatcg acggcataaa cataactaat gagaacgatc
      301 tatacacagc attagacata ttaaatcaat ctatttacga atggattgaa gagaacacag
      361 atgaacagga cagactaatt aacttagtca tgaaatggta ggaggtcgct atgaagcaga
      421 ctgtaactta tctaatcaag cataaagatg aaaatctatt tattacaaac cgaccaaccg
      481 aagtgaacga cacagtgaag tattcaactg atatgcgaga cgcaagagaa ttcgacggac
      541 tagacaaaac tgttattgat atgtctaagc acaaagcaat caagaaaaca gtgacagaaa
      601 caattgagta
//
LOCUS       DAPDIM010000175          606 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000175 DAPDIM010000000
VERSION     DAPDIM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.186"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(479..593)
                     /gene="rrf"
                     /locus_tag="RFE25_002881"
     rRNA            complement(479..593)
                     /gene="rrf"
                     /locus_tag="RFE25_002881"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          162 a          138 c           95 g          211 t
ORIGIN      
        1 gatttaaaag atattagaca taaaatctaa aaacagcagt aagatgattt atgattaaaa
       61 actatcttac tgctgttcac tttttataat acttctgaat gtcttcactt atacttctag
      121 tcacagattt aaataatcaa aagtgcacat tattaaaata tcaatttcac actcaatgcg
      181 gctcatcgca ttcatttctt gtctagcaac gttctactct agcggaacgt aagttggcta
      241 ccatcctcgc taagaacctt tcttgacttg tgacaatcgc ttgcttcttt cctctccttc
      301 ggctctcgct tactcattta gctctactaa actcgttgcg ctcttttctc gtttcgtcag
      361 attcaaacgt tttcacttcg ccaagccatt tttctttgtg tttacttttt attttgacgt
      421 tttagacata aaaaaagaga ccttgcggtc tcaatgcggc tcatcgcatc cattttttgc
      481 ctggcaacgt tctactctag cggaacgtaa gttcgactac catcgacgct aaggagctta
      541 acttctgtgt tcggcatggg aacaggtgtg acctccttgc tatagtcacc agacatatga
      601 atgtaa
//
LOCUS       DAPDIM010000176          597 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000176 DAPDIM010000000
VERSION     DAPDIM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.187"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            70..255
                     /locus_tag="RFE25_002882"
     CDS             70..255
                     /locus_tag="RFE25_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817856.1"
                     /translation="MLNLKELREEKGITRYQLAKLTELQNSTIQSIETEVKNPGFLTV
                     KKICDALQVDIANVKEK"
     gene            257..>597
                     /locus_tag="RFE25_002883"
     CDS             257..>597
                     /locus_tag="RFE25_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HDU2817857.1"
                     /translation="MQALQTKSNIGEMFNIQEKENGEIAISGRELHQALEVKTPYKKW
                     FERMSDYGFEENIDYVVTDIFVHNPLGGRQNQTDHALTLDTAKEIAMIQRSEPGKRAR
                     QYFIQVEKAWN"
BASE COUNT          245 a          103 c          118 g          131 t
ORIGIN      
        1 cctcccagtg tagtggggtt ggattaatta tataacgaaa tatcgttata gacaataagg
       61 agtggtaaga tgctgaactt aaaagaattg agagaagaaa aggggataac acgctatcaa
      121 ctagcgaagc taacagaatt acaaaattcg acaattcaat ctatcgaaac agaagttaaa
      181 aatcccggct tcctcacagt aaaaaaaata tgcgatgcac tacaagttga tatcgctaat
      241 gtaaaggaga aataaaatgc aagcattaca aacaaaatcg aacatcggcg aaatgttcaa
      301 tatacaagaa aaagaaaatg gagaaatcgc aatcagcggt cgagaacttc atcaagcatt
      361 agaagttaag actccataca aaaaatggtt tgaaagaatg agtgattacg gatttgaaga
      421 aaatatcgat tatgtagtta cggacatttt tgtccataac ccactaggag gtcgtcagaa
      481 tcaaactgac cacgcactca cactagacac tgcaaaagaa atcgcaatga ttcaacgtag
      541 tgaacctggc aaacgtgcaa ggcaatactt catccaagtt gaaaaagcat ggaacag
//
LOCUS       DAPDIM010000177          558 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000177 DAPDIM010000000
VERSION     DAPDIM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.189"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>558
                     /locus_tag="RFE25_002884"
     CDS             <1..>558
                     /locus_tag="RFE25_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HDU2817858.1"
                     /translation="QTLFEQLNSKNVNDHTEQKNGLTYLAWSYAHQELKKIDPNYTVK
                     VHEFPHPDINTENYFVPYLATPEGYFVQVSVTVKDSTETEWLPVLDFRNKSLAKGSAT
                     TFDINKAQKRCFVKASALHGLGLYIYNGEELPSASDNDITELEERINQFVNLSQEKGR
                     DATIDKTMRWLKISNINKLSQKQIA"
BASE COUNT          218 a           95 c          103 g          142 t
ORIGIN      
        1 acaaacatta tttgaacagt tgaacagtaa aaacgtgaat gatcatacag aacaaaaaaa
       61 tggattaact tatctagcat ggtcatatgc acaccaagag ctgaaaaaga ttgacccaaa
      121 ctacacagta aaagtacacg agtttccaca tccagatatt aacacagaaa attattttgt
      181 accttatttg gctacaccag aaggctattt tgtacaggta tctgtgactg tgaaagatag
      241 tacagagact gagtggcttc cagtattgga ctttagaaat aaatcgcttg ctaaaggtag
      301 tgcaacaact ttcgatatta acaaagcgca aaaacgatgt tttgttaaag cttcggcttt
      361 acacggttta ggcttatata tctacaacgg cgaggaacta ccaagtgcaa gtgacaacga
      421 tattacagaa ttagaagagc gtatcaatca gttcgtgaac ttatctcaag aaaaagggcg
      481 agatgcaact atcgataaaa cgatgagatg gctaaaaata tctaacatta ataaattaag
      541 tcaaaaacaa atcgcaga
//
LOCUS       DAPDIM010000178          533 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000178 DAPDIM010000000
VERSION     DAPDIM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.190"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            290..463
                     /locus_tag="RFE25_002885"
     CDS             290..463
                     /locus_tag="RFE25_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817859.1"
                     /translation="MWNFIKCVFKFVFSLVAITTLVAGVGVVAFAYIFKKDFEDIERK
                     TKEIISDIESKNN"
BASE COUNT          201 a           50 c           88 g          194 t
ORIGIN      
        1 atttttatag atggtgggga tattaagtta aaaacttaaa atcatcttat cataaataac
       61 aatcttaagt tagcattcac gataatagtc attgttaaca ttagcatata aggtcatgtc
      121 acgttgaaac agaggttcct cggcattttt gaaaataatc attagcttgc tcactatata
      181 atttgatgaa tatatttcgt aaaagtgggt atttatttaa tgattattct atatatgata
      241 gtataatgaa atgtagatag gtatttaatt taacagaggt gaaattgaga tgtggaattt
      301 tattaaatgt gtgtttaaat tcgtatttag cttagttgct attacaacat tagttgctgg
      361 tgttggtgta gtagcatttg cttatatctt taaaaaagat tttgaagata ttgaaagaaa
      421 aactaaagaa attatttctg atattgaaag taaaaataac taataacatt tagaggctgg
      481 gacataaatc cctaaaaaac agcagtaaga taattttcaa ttagaaaata tct
//
LOCUS       DAPDIM010000179          531 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000179 DAPDIM010000000
VERSION     DAPDIM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.191"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(38..>531)
                     /locus_tag="RFE25_002886"
     rRNA            complement(38..>531)
                     /locus_tag="RFE25_002886"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          124 a          152 c          119 g          136 t
ORIGIN      
        1 gtaagtaaaa gtgattttgc ttcgcaaaac atttattttg attaagtctt cgatcgatta
       61 gtattcgtca gctccacatg tcaccatgct tccacctcga acctattaac ctcatcatct
      121 ttgagggatc ttataaccga agttgggaaa tctcatcttg aggggggctt catgcttaga
      181 tgctttcagc acttatcccg tccacacata gctacccagc tatgccgttg gcacgacaac
      241 tggtacacca gaggtatgtc catcccggtc ctctcgtact aaggacagct cctctcaaat
      301 ttcctacgcc cacgacggat agggaccgaa ctgtctcacg acgttctgaa cccagctcgc
      361 gtaccgcttt aatgggcgaa cagcccaacc cttgggaccg actacagccc caggatgcga
      421 tgagccgaca tcgaggtgcc aaacctcccc gtcgatgtga actcttgggg gagataagcc
      481 tgttatcccc ggggtagctt ttatccgttg agcgatggcc cttccatgcg g
//
LOCUS       DAPDIM010000180          529 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000180 DAPDIM010000000
VERSION     DAPDIM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.192"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            35..>529
                     /locus_tag="RFE25_002887"
     CDS             35..>529
                     /locus_tag="RFE25_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDU2817860.1"
                     /translation="MGLPNPKTRKPTASEVVEWALYMAKNRRVIDVDRAYGGQCWDVP
                     NYILERYWGFRTWGNANAMAQKSNYRGRDFKIYRNTASFTPKPGDWAVWANRNPGHVA
                     IVVGPADKNAFVSVDQNWYTANWSGSPPYKIKHTYHDGPGGVTHFVRPPYHPDKTTPA
                     PQPAP"
BASE COUNT          163 a          100 c          127 g          139 t
ORIGIN      
        1 tggcttttta ttttgattga aatgaggtgc atacatggga ttacctaacc caaagactag
       61 aaagcctaca gctagtgaag tggtggagtg ggcactgtat atggctaaaa acagaagagt
      121 tatagatgtt gacagagcat acggcgggca atgttgggat gttcctaact atattttaga
      181 acgatattgg gggttcagaa cttggggcaa cgcaaatgct atggctcaaa aatccaatta
      241 tcgcggtaga gattttaaaa tttatagaaa cacagctagt tttacgccta agccgggaga
      301 ttgggcagtt tgggctaata gaaacccggg tcatgtagcg atagttgttg gtccagctga
      361 taaaaatgcg tttgtttcag tagatcagaa ttggtataca gctaattggt ctggcagtcc
      421 tccctataaa atcaaacata cttatcacga tgggcctgga ggagtaacac attttgttag
      481 accaccatat catccagaca aaactacacc ggcaccccaa ccggcaccc
//
LOCUS       DAPDIM010000181          519 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000181 DAPDIM010000000
VERSION     DAPDIM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.193"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            131..381
                     /locus_tag="RFE25_002888"
                     /pseudo
     CDS             131..381
                     /locus_tag="RFE25_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016187510.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sphingomyelin phosphodiesterase"
BASE COUNT          211 a           68 c           63 g          177 t
ORIGIN      
        1 attatattta cagcatcttt atactcaaaa aacatttact taaaaatata aattcgattt
       61 aataattaat ttaaatttag ttaatcaatt ttgcatctat tttgttgtaa gctatataaa
      121 aggagtgata atgatggtaa aaaaaacaaa atccaattca ctaaaaaaag ttgcaacact
      181 tgcattagca aatttattat tagttggtgc acttactgac aatagtgcca aagccgaatc
      241 taagaaagat gatactgatt tgaagttagt tagtcataac gtttatatgt tatcgaccgt
      301 tttgtatcca aactggagac ttttaacata aaattactta tcattcaaaa agtaaaacag
      361 cataatatca aggtttataa ctttatcatt atcaataata cctcatataa aataaaattt
      421 tagggacttt ttagggactt taaatttaaa attacaagtt taatagaaac atcaaaataa
      481 tcacatgttt gtgtggaatg tacaccccaa aagctagac
//
LOCUS       DAPDIM010000182          479 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000182 DAPDIM010000000
VERSION     DAPDIM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.194"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            126..365
                     /locus_tag="RFE25_002889"
     CDS             126..365
                     /locus_tag="RFE25_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001656966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817861.1"
                     /translation="MSDNLSLFIDYINDNIIYGSEIKREKLENLFNQFAIKNVEKNIV
                     YDELKSLDITIIESQDSYKNKLKRLFSVLLQSKKI"
     gene            complement(397..>479)
                     /locus_tag="RFE25_002890"
     CDS             complement(397..>479)
                     /locus_tag="RFE25_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDU2817862.1"
                     /translation="LYKKNRRSLQIYGFSPCHEISIMLAS"
BASE COUNT          170 a           49 c           86 g          174 t
ORIGIN      
        1 atattcaagt aattttattg ttttttaatt tgtcgatatt taagttgagt taaatttaaa
       61 gggtgtaatt tgttttacaa tgatgaagat aattagtcta tcaaaataaa ggggttggga
      121 ctgttatgag tgataatttg tcattattca ttgactatat caatgataat ataatctatg
      181 gtagtgaaat caaacgggag aaattagaga atttatttaa tcaatttgct ataaaaaatg
      241 ttgaaaagaa cattgtctat gatgaactga aatctttaga tattacaatc attgagtcac
      301 aggattcata taaaaataaa ttgaagagat tattttcggt tctgttgcaa agtaaaaaaa
      361 tatagctaac cactaattta tcatgtcagt gttcgcttaa cttgctagca tgatgctaat
      421 ttcgtggcat ggcgaaaatc cgtagatctg aagagacctg cggttctttt tatatagag
//
LOCUS       DAPDIM010000183          393 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000183 DAPDIM010000000
VERSION     DAPDIM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.196"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..364
                     /locus_tag="RFE25_002891"
     CDS             <1..364
                     /locus_tag="RFE25_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDU2817863.1"
                     /translation="SKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASL
                     DDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLM
                     DLHDEWIYSSRKYINFDK"
BASE COUNT          146 a           69 c           66 g          112 t
ORIGIN      
        1 ttcaaaatct ttcagagaag ctgttaaagg aatttttaag ttcacagata ttaacttagc
       61 gcgtgaggct aaaaatcgat tgattcatga ttatatcgat caaccaaaat attcaaaagc
      121 ttgcgcatca ttggatgatg gattcgaaga cgcctttcaa tataccgtac aaggaaattc
      181 ccacaatcga ctaaagagta ccaatctaat tgaacgactg aatcaagaag tacgcagaag
      241 agaaaagatt attcgcatct tccccaatca aacatcagcc aatcgcttaa ttggagccgt
      301 tcttatggac ctacatgatg aatggattta ttcttcaaga aaatacatca attttgataa
      361 gtagaaatgg taaaaacatt gtatagcatt tta
//
LOCUS       DAPDIM010000184          357 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000184 DAPDIM010000000
VERSION     DAPDIM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.198"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..129
                     /locus_tag="RFE25_002892"
     CDS             <1..129
                     /locus_tag="RFE25_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDU2817864.1"
                     /translation="ELSTKAPKEYDTSQPFTDASNDVGFDVNEYHHGGGDNASKIN"
     gene            110..>357
                     /locus_tag="RFE25_002893"
     CDS             110..>357
                     /locus_tag="RFE25_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HDU2817865.1"
                     /translation="MQAKLTKKEFIEWLKTSEGKQFNADLWYGFQCFDYANAGWKVLF
                     GLLLKGLGAKDIPFANNFDGLATVYQNTPDFLAQPGDMV"
BASE COUNT          120 a           65 c           76 g           96 t
ORIGIN      
        1 gaattaagca cgaaagcacc aaaagaatat gatacatcac aacctttcac agacgcctct
       61 aacgatgttg gctttgatgt gaatgagtat catcatggag gtggcgacaa tgcaagcaaa
      121 attaactaaa aaagagttta tagagtggtt gaaaacttct gagggaaaac aatttaatgc
      181 agatttatgg tatggatttc agtgtttcga ctatgccaat gctggctgga aagttttgtt
      241 cggattactc ctaaaaggtt taggcgcaaa agatattcca ttcgctaaca acttcgacgg
      301 attagctact gtataccaaa atacaccgga cttcttagca caacctggcg acatggt
//
LOCUS       DAPDIM010000185          357 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000185 DAPDIM010000000
VERSION     DAPDIM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.199"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..129
                     /locus_tag="RFE25_002894"
     CDS             <1..129
                     /locus_tag="RFE25_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDU2817866.1"
                     /translation="ELSTKAPKEYDTSQPFTDASNDVGFDVNEYHHGGGDDASKIN"
     gene            110..>357
                     /locus_tag="RFE25_002895"
     CDS             110..>357
                     /locus_tag="RFE25_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HDU2817867.1"
                     /translation="MQAKLTKKEFIEWLKTSEGKQFNVDLWYGFQCFDYANAGWKVLF
                     GLLLKGLGAKDIPFANNFDGLATVYQNTPDFLAQPGDMV"
BASE COUNT          121 a           56 c           78 g          102 t
ORIGIN      
        1 gaattaagta caaaagcacc gaaagaatat gatacatcac agccgtttac agacgcctct
       61 aacgatgttg gttttgacgt gaatgagtat catcatggag gtggcgacga tgcaagcaaa
      121 attaactaaa aaagagttta tagaatggtt gaaaacttct gagggaaaac aattcaatgt
      181 ggacttatgg tatggatttc aatgctttga ttatgccaat gctggttgga aagttttgtt
      241 tggattactt ctaaaaggtt taggtgcaaa agatatacca tttgcaaaca attttgatgg
      301 actagctact gtataccaaa atacaccgga cttcttagca caacctggcg acatggt
//
LOCUS       DAPDIM010000186          357 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000186 DAPDIM010000000
VERSION     DAPDIM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.200"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
BASE COUNT          146 a           35 c           59 g          117 t
ORIGIN      
        1 tatggagttc tttctttttt acaagatgta tatgtataaa tggaaatgtt tattacatta
       61 cataaaaacc tttaggtgct cttagatgga tgttaatcat aaaaaaagag attttgaaaa
      121 atataggcta ttataattta gaattacaaa ttataaatct tgccagtgga tatgggagtt
      181 caacatgtca cttaccccaa tttgtggaat gttaaataac tataaagagg aaaggagaaa
      241 aaatgataag aatggttaaa gaaaaagaac gaatagcaaa attaaatttc gaatagctgt
      301 gacgagctta ataattcaag tacttaattt tatcaaatcg ttcttttaaa aaggtaa
//
LOCUS       DAPDIM010000187          347 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000187 DAPDIM010000000
VERSION     DAPDIM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.201"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>347
                     /locus_tag="RFE25_002896"
     CDS             <1..>347
                     /locus_tag="RFE25_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HDU2817868.1"
                     /translation="NGLVNAPLSRLEAGIAHSYVSGNTVWQALDESQVGWHTANQIGN
                     KYYYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTSCP
                     HRSSVLHTGFDPV"
BASE COUNT          123 a           63 c           70 g           91 t
ORIGIN      
        1 gtaacggatt agtaaatgca cctttatcaa gattagaagc gggcattgcg catagttacg
       61 tatcaggcaa cacagtttgg caagccttag atgaatcaca agtaggttgg cataccgcta
      121 atcaaatagg taataaatat tattacggta ttgaagtatg tcaatcaatg ggcgcagata
      181 acgcgacatt cttaaaaaat gaacaggcaa ctttccaaga atgcgctaga ttgttgaaaa
      241 aatggggatt accagcaaac agaaatacaa tcagattgca caatgaattt acttcaacat
      301 catgccctca tagaagttcg gttttacaca ctggttttga cccagta
//
LOCUS       DAPDIM010000188          345 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000188 DAPDIM010000000
VERSION     DAPDIM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.202"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>345
                     /locus_tag="RFE25_002897"
     CDS             <1..>345
                     /locus_tag="RFE25_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HDU2817869.1"
                     /translation="AGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGIEQPGWGWEKVT
                     RRQHAYDFPMWFIRPNFKSETAPRSVQSPTQAPKKETAKPQPKAVELKIIKDVVKGYD
                     LPKRGSNPKGIVI"
BASE COUNT          115 a           66 c           79 g           85 t
ORIGIN      
        1 gctggatatg gtcacgttgc atgggtaatt gaagcaactt tagattacat cattgtatat
       61 gagcagaatt ggctaggcgg tggctggact gacggaatcg aacaacccgg ctggggttgg
      121 gaaaaagtta caagacgaca acatgcttat gatttcccta tgtggtttat ccgtccgaat
      181 tttaaaagtg agacagcgcc acgatcagtt caatctccta cacaagcacc taaaaaagaa
      241 acagctaagc cacaacctaa agcagtagaa cttaaaatca tcaaagatgt ggttaaaggt
      301 tatgacctac ctaagcgtgg tagtaaccct aaaggtatag ttata
//
LOCUS       DAPDIM010000189          333 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000189 DAPDIM010000000
VERSION     DAPDIM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.203"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
BASE COUNT          137 a           42 c           70 g           84 t
ORIGIN      
        1 atgtctaaaa cgtcaaaata aaagttaaca caaagaaaat ggcttgacga agtgaaaacg
       61 tttgaatctg acgaaacgag aaaagagcgc aacgagttta gtagagctaa atgagtaagc
      121 gagagccgaa gaagaggaaa gaagcaagcg attgtcacaa gtcaagaaag gttcttagcg
      181 aggatggtag ccaacttacg ttccgctaga gtagaactgg aaatgataat ttaataatgt
      241 acactttcga ttgtctaagt atgtacaact ttaattttgt gtttatataa atttaaaatg
      301 atatcatcga aaacaaaata ttgtataaat aga
//
LOCUS       DAPDIM010000190          315 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000190 DAPDIM010000000
VERSION     DAPDIM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.204"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..>315)
                     /gene="fmhC"
                     /locus_tag="RFE25_002898"
     CDS             complement(<1..>315)
                     /gene="fmhC"
                     /locus_tag="RFE25_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FemA/FemB family glycyltransferase FmhC"
                     /protein_id="HDU2817870.1"
                     /translation="TEELILEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAY
                     HLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPV
                     RPI"
BASE COUNT          107 a           59 c           37 g          112 t
ORIGIN      
        1 aattggtctt actggtttga tgaaatcacc aattaattct tcaacatgtg cattaaaacc
       61 ctttttaaat tgttgaacac caaaatcatc cgcctcatta ctaaagacgc ctgttattcc
      121 ataaaaatta tacctattaa tattatgtga ttttgcatat tttatcatat gccattgtag
      181 atgatatgca cccatatact gattatattt cggatttgat ccacttgata gataataaac
      241 ttcatcatca gtacatataa ataaagcagc agctaaatcc aaaacaggtc catcttctaa
      301 tattagttct tcggt
//
LOCUS       DAPDIM010000191          310 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000191 DAPDIM010000000
VERSION     DAPDIM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.205"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            36..>310
                     /gene="ssb"
                     /locus_tag="RFE25_002899"
     CDS             36..>310
                     /gene="ssb"
                     /locus_tag="RFE25_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDU2817871.1"
                     /translation="MLNRAVLVGRLTKDPELRSAPNGVNVGTFTLAVNRTFTNAQGER
                     EADFINVVVFKKQAENVKNYLSKGSLAGVDGRLQTRSYENKVGQRVFV"
BASE COUNT          118 a           49 c           75 g           68 t
ORIGIN      
        1 ggattaaaac aattggatag tgaggagaaa caataatgtt aaacagagca gtattagtag
       61 gacgcttaac aaaagaccca gaattaagaa gcgcgccaaa tggcgtaaat gtaggtacat
      121 tcacattggc agtaaacaga acattcacga atgctcaagg cgagcgtgaa gcagatttta
      181 taaacgtagt agtgttcaag aaacaagctg aaaatgttaa aaactacctt tctaaagggt
      241 cgctggcagg tgtagacggg cgattacaaa cacgtagcta cgaaaataaa gtcgggcaac
      301 gtgtatttgt
//
LOCUS       DAPDIM010000192          310 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000192 DAPDIM010000000
VERSION     DAPDIM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.206"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            36..>310
                     /gene="ssb"
                     /locus_tag="RFE25_002900"
     CDS             36..>310
                     /gene="ssb"
                     /locus_tag="RFE25_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDU2817872.1"
                     /translation="MLNRTVLVGRLTKDPEYRTTPNGVSVTTFTIAVNRTFTNAQGER
                     EADFINCVTFRKQAENVNNYLSKGSLAGVDGRLQSRSYENKDGQRVFV"
BASE COUNT          118 a           46 c           66 g           80 t
ORIGIN      
        1 ggattaaaac aattggatag tgaggagaaa caataatgtt aaatagaaca gtattagtag
       61 gacgcttaac aaaagatcca gaatatagaa caacgccaaa tggtgtgagt gttaccactt
      121 tcactatcgc agttaacaga acatttacta acgctcaagg agaacgtgag gcagacttta
      181 ttaactgtgt aacttttaga aaacaagcag aaaatgtaaa taattattta tccaaagggt
      241 cattggctgg cgttgatgga cgtttacaat cacgcagtta tgaaaacaaa gacgggcaac
      301 gtgtatttgt
//
LOCUS       DAPDIM010000193          292 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000193 DAPDIM010000000
VERSION     DAPDIM010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.207"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
BASE COUNT          136 a           43 c           20 g           93 t
ORIGIN      
        1 tagctaccat acaagtatta acaaacatcc caacaatccc aaaacttgta tgtgctaact
       61 tatgcataaa actacaagtg taaataaact tgctttctat tcaattgtca aagttgaata
      121 aaattaaata agtataaaaa ccaataatca atagagttaa tatttagaaa taagataata
      181 gtacataaaa caaatcactc tattacatat taattttata atttatatac aaagaaaata
      241 tatcaatatt accattaaat tgcaacaatt ctacatatat ttcttcaaaa aa
//
LOCUS       DAPDIM010000194          279 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000194 DAPDIM010000000
VERSION     DAPDIM010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.208"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>279
                     /locus_tag="RFE25_002901"
     rRNA            <1..>279
                     /locus_tag="RFE25_002901"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           89 a           56 c           76 g           58 t
ORIGIN      
        1 taagggcgca cggtggatgc cttggcacta gaagccgatg aaggacgtta ctaacgacga
       61 tatgctttgg ggagctgtaa gtaagctttg atccagagat ttccgaatgg ggaaacccag
      121 catgagttat gtcatgttat cgatatgtga atacatagca tatcagaagg cacacccgga
      181 gaactgaaac atcttagtac ccggaggaag agaaagaaaa ttcgattccc ttagtagcgg
      241 cgagcgaaac gggaagagcc caaaccaaca agcttgctt
//
LOCUS       DAPDIM010000195          260 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000195 DAPDIM010000000
VERSION     DAPDIM010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..260
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.209"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(6..>260)
                     /locus_tag="RFE25_002902"
     rRNA            complement(6..>260)
                     /locus_tag="RFE25_002902"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           63 a           73 c           60 g           64 t
ORIGIN      
        1 cttagaaagg aggtgatcca gccgcacctt ccgatacggc taccttgtta cgacttcacc
       61 ccaatcattt gtcccacctt cgacggctag ctcctaaaag gttactccac cggcttcggg
      121 tgttacaaac tctcgtggtg tgacgggcgg tgtgtacaag acccgggaac gtattcaccg
      181 tagcatgctg atctacgatt actagcgatt ccagcttcat gtagtcgagt tgcagactac
      241 aatccgaact gagaacaact
//
LOCUS       DAPDIM010000196          250 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000196 DAPDIM010000000
VERSION     DAPDIM010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..250
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.denovo.212"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            <1..>250
                     /locus_tag="RFE25_002903"
     CDS             <1..>250
                     /locus_tag="RFE25_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDU2817873.1"
                     /translation="PFEKKREFNPDLKPGEEKVTQEGQTGEKTTTTPTTINPLTGEKV
                     GEGEPTTEVTKEPVDEITQFGGEEVPQGHKDEFDPNLPI"
BASE COUNT          115 a           47 c           52 g           36 t
ORIGIN      
        1 ccattcgaga aaaaacgtga gttcaatcca gacttaaaac caggtgaaga gaaagtaacg
       61 caagaaggac aaactggaga gaaaacaaca acaacgccaa caacaattaa tccattaacg
      121 ggagaaaaag taggcgaagg tgaaccaaca acagaagtaa caaaagaacc agtagatgaa
      181 atcacacaat tcggtggaga agaagtacca caaggtcata aagatgagtt cgatccaaac
      241 ttaccaattg
//
LOCUS       DAPDIM010000197         6701 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.101, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000197 DAPDIM010000000
VERSION     DAPDIM010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6701
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.101"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(234..2417)
                     /gene="cadA"
                     /locus_tag="RFE25_002904"
     CDS             complement(234..2417)
                     /gene="cadA"
                     /locus_tag="RFE25_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase CadA"
                     /protein_id="HDU2817874.1"
                     /translation="MSEQKVKLMEEEMNVYRVQGFTCANCAGKFEKNVKKIPGVQDAK
                     VNFGASKIDVYGNASVEELEKAGAFENLKVSPEKLANQTIQRVKDDTKAHKEEKTPFY
                     KKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVGSIVIGGYSLFKVGFQNLIRFDF
                     DMKTLMTVAVIGAAIIGEWAEASIVVVLFAISEALERFSMDRARQSIRSLMDIAPKEA
                     LVMRNGQEIMIHVDDIAVGDIMIVKPGEKIAMDGIIINGVSAVNQAAITGESVPVAKT
                     VDDEVFAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAPAQAFVDKFAKYYT
                     PIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAK
                     KGVLIKGGVYLEELGAIKAIAFDKTGTLTKGVPVVTDFEVLNDQVEEKELFSIITALE
                     YRSQHPLASAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGTTYYIGSPKLFKEL
                     NVSDFSLGFENNVKILQNQGKTAMIIGTEKTILGVIAVADEVRETSKNVIQKLHQLGI
                     KQTIMLTGDNQGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDNVAMIGDGVND
                     APALAASTVGIAMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFA
                     IGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMRVKDK"
     gene            complement(2410..2778)
                     /gene="cadC"
                     /locus_tag="RFE25_002905"
     CDS             complement(2410..2778)
                     /gene="cadC"
                     /locus_tag="RFE25_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory
                     transcriptional repressor CadC"
                     /protein_id="HDU2817875.1"
                     /translation="MKKKDTCEIFCYDEEKVNRIQGDLQTVDISGVSQILKAIADENR
                     AKITYALCQDEELCVCDIANILGVTIANASHHLRTLYKQGVVNFRKEGKLALYSLGDE
                     HIRQIMMIALAHKKEVKVNV"
     gene            complement(3341..4186)
                     /gene="blaZ"
                     /locus_tag="RFE25_002906"
                     /pseudo
     CDS             complement(3341..4186)
                     /gene="blaZ"
                     /locus_tag="RFE25_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
     gene            4293..6050
                     /gene="blaR1"
                     /locus_tag="RFE25_002907"
     CDS             4293..6050
                     /gene="blaR1"
                     /locus_tag="RFE25_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="HDU2817876.1"
                     /translation="MAKLLIMSIVSFCFIFLLLLFFRYILKRYFNYMLNYKVWYLTLL
                     AGLIPFIPIKFSLFKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFATDIHKFNWDSI
                     DNICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIV
                     IRKAETIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFN
                     IFSIIMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLNVPFFN
                     KNILSHSFNGKKSLLKRRLINIKEANLKKQSKLILIFICIFTFLLMVIQSQFLMGQSI
                     TDYNYKKPLHNDYQILDKSKIFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPNSTYK
                     IYLAMFGLDRHIINDENSRMSWNHKHYPFDAWNKEQDLNTAMQNSVNWYFERISDQIP
                     KNYTATQLKQLNYGNKNLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQ
                     LSSSLLIKKNEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGKPSGK
                     NAELISEKILKEMGVLNGQ"
     gene            6040..6420
                     /gene="blaI"
                     /locus_tag="RFE25_002908"
     CDS             6040..6420
                     /gene="blaI"
                     /locus_tag="RFE25_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillinase repressor BlaI"
                     /protein_id="HDU2817877.1"
                     /translation="MANKQVEISMAEWDVMNIIWDKKSVSANEIVVEIQKYKEVSDKT
                     IRTLITRLYKKEIIKRYKSENIYFYSSNIKEDDIKMKTAKTFLNKLYGGDMKSLVLNF
                     AKNEELNNKEIEELRDILNDISKK"
BASE COUNT         2309 a         1097 c          963 g         2332 t
ORIGIN      
        1 cgaacactga catgataaat tagtggttag ctatattttt actttgcaac agaaccagaa
       61 ttaatataac gagatatcaa ttcctgttgc tacatatacc gcagctgctg taagtatcgt
      121 tgcgatcatt tttccatctc caatatttta tattttaggg gtaggacttt tcttcaaatt
      181 gaaaagcccc ccttgaattg cgcacagcgt gaccttacta ttctgttttc tacctattta
      241 tccttcactc tcatcagtcg taaactattt aatgctacca aaatagtagc tcccatatcg
      301 gaaagaatcg ctatccaaag ggttaaccat cccgggataa ctaatagtaa ggcaattatt
      361 ttaattccga tagcaaaagt gatgttagct ttaatgatat ttaaagtttt tcgactgagt
      421 cttactgcaa atggaagctt acttaaatca tctcccatta atgcaatatc agctgtttca
      481 attgcagtat ccgttccagc accgcccatt gcaattccaa cagtagatgc agcaagtgct
      541 ggagcatcat taacgccatc gccaatcata gctacattat catactccga ttgcattttt
      601 ttaatataat ctaatttatc ctgtggcatc aattcagact gaatatcaga aacgcctaca
      661 tgtgtaccga ttgcatttgc agtaccttga ttatcacctg tcagcataat tgtttgcttg
      721 atacctaact gatgaagttt ttgaatcaca tttttacttg tttcacgaac ctcatctgca
      781 acggcaatta cgccgagaat tgttttttcc gttccaataa tcatggctgt ttttccttgg
      841 ttttgtagga ttttcacatt gttttcaaac ccaaggctaa aatcggaaac atttaattcc
      901 ttgaaaagtt ttgggcttcc aatatagtaa gtagttccgt ttacaatccc ttttatacct
      961 cgcccagtaa tcgaagtgaa ttcttccact tgtacattag aataagggat attatcttgc
     1021 tctgcctttt tcattattgc tgaagcaagt ggatgttgtg aacgatattc taaagctgta
     1081 atgatagaga atagctcttt ttcttccact tggtcattta atacttcaaa atctgttacc
     1141 actggtacac cttttgtcag tgttcctgtt ttatcaaatg cgattgcctt aatggctcct
     1201 aattcttcta gatagacacc gcctttaatc aacacacctt ttttagctgc atttccaatt
     1261 gccgagacaa tcgagattgg agtagaaata actaatgcac acggacatcc aactacaagt
     1321 accgctaatc cttgataaac ccaagtatcc caacttccac caaagaataa aggtggaacg
     1381 actgcaacga gcgccgcaat aaccataatg atcggcgtat aatatttcgc aaatttatct
     1441 acgaatgctt gcgctggagc gcgctcccct tgtgcttcct caaccagatg aataatcttg
     1501 gagatagttg tatcctctac gtatttggtg atttttactt caagtagtcc ctcttcgtta
     1561 agcgtacctg caaatacttc atcatctacc gttttggcaa cagggacaga ttctcctgtt
     1621 atagcagcct ggttgacagc cgacacacca tttataatga tcccatccat ggcaattttc
     1681 tcccctggtt tgacgatcat aatatcaccc acggcaatat cgtccacatg gatcattatt
     1741 tcctgaccat tccgcataac aagtgcttct tttggggcaa tatccatcaa tgaacgaatg
     1801 gactgtcttg ctctatccat agaaaaacgt tcaagtgctt cactgattgc aaagagaacg
     1861 acaacaatgg atgcctctgc ccattcacca atgatggcag ctccaataac tgctacggtc
     1921 atcagggttt tcatgtcgaa atcaaagcgt atcaaatttt gaaaaccaac tttaaatagt
     1981 gaatatccgc caattacaat cgaacctaca aataacatgg aagttacgag gttatcttct
     2041 ccatttacaa agtgagaaag gtaaccaaaa gcaattagta gtgtggcaaa cagcaatgta
     2101 ctatgttttt tataaaatgg tgttttctct tctttatgag ccttagtgtc atctttaacc
     2161 ctttgtatcg tttgattcgc tagtttttca ggagatactt ttagattctc aaaagcacct
     2221 gctttttcaa gttcttcaac cgatgcattt ccatatacat caattttaga agcgccaaag
     2281 tttacttttg cgtcctgaac gcctggaatc tttttaacat ttttctcaaa ctttcctgca
     2341 caatttgcac atgtaaatcc ttggacccga tagacgttca tttcttcttc cattagttta
     2401 accttttgtt cagacattga ccttcacttc tttcttatgt gctagggcga tcatcattat
     2461 ctgcctgata tgttcatcac ctaaagaata taaagctagt tttccttctt ttctaaagtt
     2521 gaccacccct tgcttataaa gcgtacgtaa atgatgagat gcatttgcta tcgtaacacc
     2581 taagatattt gctatatcac aaacacacaa ctcttcatcc tgacacagag cgtaagtaat
     2641 ttttgctcta ttttcatcgg caatagcctt taaaatttgg ctaacaccag aaatatcaac
     2701 tgtttgtaaa tccccttgta ttcgattaac cttttcttcg tcataacaaa aaatttcaca
     2761 agtatctttc tttttcatat tatcatccca tcttcattca aatatttatt tgagtgtatt
     2821 ataaccattt tcgactcatc atgcaagcaa atatttgaat gaaaataaaa gaagtaagta
     2881 gggcataaaa ttctagtctc aaaaacgaac ggttttgacc agggtatgac attagaaaat
     2941 aatacatttc aataagtaaa ataatttatt aaaaaataca cttgaataag tgctatttat
     3001 aaaggttaaa ggcttgtaga actaaataaa ttctataagt gtcactttgc ttgatatatg
     3061 agaattattt aaccttataa atgagaaaaa agcaacgcac tttaaataag atacgttgct
     3121 ttttcgattg atgaacacct ataattaaac tattcatcta ttatttataa ttttttgtat
     3181 atacaatatt tctagtttgt taaagagaat taagaaaata aatctcgaaa ataatagagg
     3241 gaaaatcagt ttttgatatc aaaattatac atgtcaacga taatacaaaa tataatacaa
     3301 aatataagat gttatcagta tttattatgc atttagaata ttaaaattcc ttcattacac
     3361 tcttggcggt ttcacttatc aacttatcat ttggcttatc acttttattg tctttattcg
     3421 taaaaatgac taaaacaata ggttcagatt ggcccttagg ataaacaaaa gcaacatcat
     3481 ttctagaagc atatgttatt gcttgaccac ttttatcagc aaccttatag tcttttggaa
     3541 caccgtcttt aattaaagta tctccgcttt tattatttaa cattaaatca agtaagaatt
     3601 ttttgttttc tttgcttaat tttccatttg cgataagttt atttaaagtc ttaccgaaag
     3661 cagcaggtgt tgaagtatct tttttgctct ttggtgaata gtaatttaat tctatctcat
     3721 atctaactgg atttgttact ttatctccta gttcttttag acgttgttta acttttttga
     3781 ttccaccgat ttcttttata attttattgt ttgctgtatt atcactatat gtcattgaag
     3841 cctcaataag tgcttttaaa gtgatatctt ttcctacata tttttctaaa ataggagaat
     3901 aagcaactat atcatctttg ttaatatgta cttttttatt taacttatta taaggtactt
     3961 attctaacaa aatagcacta tttatcgctt ttgaagttga agcataggca aatctcttat
     4021 ctgaattaaa ttttacttcc ttaccacttt tagtatctaa agcataaaca ccaatatgag
     4081 cattatattt tttttctaaa tcatttaact ctttggcatg tgaactgttt gaattacatg
     4141 cacttaaaac taaagcaatt acaattaaaa atattaactt tttcaaaata aaccctccga
     4201 tattacagtt gtaattttta taaatcaata atattacaat tgtaatatcg gtgtcaatag
     4261 tttattataa atatttgaaa gaaggtgttg aaatggctaa gttattaata atgagcatag
     4321 taagcttttg ttttatattt ctattgttat tattttttag gtacatatta aaacgctatt
     4381 ttaattatat gttaaattat aaagtttggt atctaactct tcttgcagga ttaattcctt
     4441 tcattcctat taaattctct ctttttaaat ttaataatgt gaataatcaa gcgcccacag
     4501 ttgaaagtaa gtcacacgac ttgaaccata acataaatac caccaaacct attcaagagt
     4561 tcgcaacaga tatccataag tttaattggg attcaattga taatatctgc acagttattt
     4621 ggatagtttt agttattatt ttaagtttta aatttttgaa agccttatta tatcttaaat
     4681 atttaaagaa acagtcactt tatctaaacg aaaatgaaaa aaataaaata gatacgatac
     4741 ttttcaacca tcaatataaa aaaaatattg tgattcgaaa agcagagact attcaatctc
     4801 caataacttt ttggtatggg aaatatatta ttttgattcc tagttcatat tttaaaagtg
     4861 taattgacaa aagactaaaa tatataatat tgcatgaata tgctcatgct aaaaatagag
     4921 atactttaca tttaattatc tttaatatct tctctattat tatgagttac aatccattag
     4981 tacatattgt aaaaagaaag ataattcatg acaatgaagt agaagccgat agatttgtcc
     5041 ttaataatat taacaaaaat gaatttaaaa cttatgcgga atctattatg gactccgtat
     5101 taaatgttcc attttttaat aaaaatatat taagccattc atttaatggt aaaaagtcat
     5161 tactcaaaag aagattaatt aatataaaag aagccaatct gaaaaaacag tccaaattaa
     5221 ttctaatttt tatttgtatt tttacttttt tgctcatggt aattcaaagc cagtttttga
     5281 tggggcaatc cataactgat tataattata aaaagccctt acacaacgat taccaaattt
     5341 tagataaaag taaaattttt ggttcaaata gtggatcttt cgtcatgtac agcatgaaga
     5401 aagacaaata ctatatttat aacgaaaaag aaagtagaaa aaggtattct cctaattcaa
     5461 cttataaaat ttatttagct atgtttggac ttgaccgaca tattataaat gatgaaaatt
     5521 cacgtatgtc atggaatcat aagcattacc cttttgatgc ttggaataag gaacaagatt
     5581 taaatacagc aatgcaaaat tcagttaatt ggtacttcga acgtattagc gatcaaatac
     5641 caaagaacta tactgcgact caactcaagc aattaaatta tggtaataaa aatttgggaa
     5701 gttataaaag ctattggatg gaagatagtt tgaaaatatc taatcttgaa caagtaatag
     5761 tttttaaaaa tatgatggaa caaaataacc attttagtaa aaaagcaaag aatcaattat
     5821 cttcttcatt attgattaag aaaaatgaaa agtatgaact gtatgggaaa acaggtacag
     5881 gtatagtaaa cgggaagtat aataatgggt ggtttgtagg ttacgtaatt acaaatcatg
     5941 ataagtatta ttttgctaca catttatcag atggaaagcc atctgggaaa aatgctgaat
     6001 taatcagtga aaaaatatta aaagaaatgg gtgttttaaa tggccaataa gcaagttgaa
     6061 atatctatgg ctgaatggga tgttatgaat ataatatggg ataaaaaatc agtatcagct
     6121 aatgaaattg tagttgaaat tcaaaaatat aaagaagtta gcgataaaac gattagaaca
     6181 ttaatcacaa gactatataa aaaagagatt ataaaacgat acaaatcaga gaatatttat
     6241 ttttactcat caaatattaa agaagacgat attaaaatga aaactgctaa aacctttctt
     6301 aataaactgt atggagggga catgaaaagt ttagtgctga attttgcgaa aaatgaagaa
     6361 ttaaataaca aagaaattga agaattgcga gacattttaa atgatattag taaaaagtaa
     6421 ttagagatat gtttcaaaca taatacatat gtaaactatg cttgactctt attaaattag
     6481 ttttgttaat aacatttaaa atatattatt aaagatgaga gtgtacagaa aataaccatt
     6541 ttctatacac tctcttttta tgtctatata tatagcgagt atacatattt tagtgttcaa
     6601 taacccaaca gaaaatctat gttcataaat atggttagaa ttaagttatg atacaatgaa
     6661 gatgtatata ggaggtttgt attttgaaaa taggttatgc a
//
LOCUS       DAPDIM010000198         5891 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.107, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000198 DAPDIM010000000
VERSION     DAPDIM010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5891
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.107"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            134..1219
                     /locus_tag="RFE25_002909"
     CDS             134..1219
                     /locus_tag="RFE25_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDU2817878.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            1216..3108
                     /locus_tag="RFE25_002910"
     CDS             1216..3108
                     /locus_tag="RFE25_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDU2817879.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            3115..3492
                     /locus_tag="RFE25_002911"
     CDS             3115..3492
                     /locus_tag="RFE25_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDU2817880.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            3643..4425
                     /locus_tag="RFE25_002912"
     CDS             3643..4425
                     /locus_tag="RFE25_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HDU2817881.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(4551..5282)
                     /gene="erm(A)"
                     /locus_tag="RFE25_002913"
     CDS             complement(4551..5282)
                     /gene="erm(A)"
                     /locus_tag="RFE25_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HDU2817882.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            5670..>5891
                     /locus_tag="RFE25_002914"
     CDS             5670..>5891
                     /locus_tag="RFE25_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDU2817883.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAK"
BASE COUNT         2126 a          792 c         1141 g         1832 t
ORIGIN      
        1 ttaaccatag tataataaat aatagtagtt aaagtagttt aagaggagat attaaaggga
       61 tattttactt taaataaaaa ttaacaaggt ttataatttg tagtagttaa agtatttaaa
      121 gaggtgggaa catgtgaagg ttcaaaggat agaagtggag aataagccgt atccattgta
      181 tttattacta gataaagaat accagctaat agaaccagta atgaaattta ttaaatactt
      241 agataatact ggtaagtctc ctaataccat taaggcatac tgctatcatt taaagttgct
      301 gtacgagttc atggaacaga gaggtgttat tcttaatgat attaactttg agttgttagc
      361 agacttcgta ggttggttga gatatccttc agcatcaaat gtaattgatc ttcagtcaaa
      421 aaaagccata agagaagaaa cgacagtgaa tacaatttta aatgtagtta tgagttttct
      481 tgattattta agtagattag gagaatttaa atcaattgat gtatttaaac aagcaaaggg
      541 aagaaatttc aaaggatttt tacatcatgt taataagggt agataccaaa agaatgtctt
      601 aaagttaagg gttaaaaaga aacagataag aacattgaga tcaaaggaag ttaagcaaat
      661 tattgatgct tgtcatacga aaagagataa attaatttta atgcttatgt atgagggtgg
      721 tttaagaatc ggtgaagtgt tatcgcttag gcttgaagat attgtcactt gggacaatca
      781 aatccattta acacctagag atgttaatgt taatgaagct tatattaaat taaggaagga
      841 aagaacaata catgtgagta aagaacttat gtcactttat acagattact tgatatatga
      901 gtatagtgag gaattggagc atgattatgt ttttatttcc ttaaaagaag gctattttgg
      961 gaaaccacta aagtaccaaa gtgttcttga tctagttaga agaatagtta aaaggactgg
     1021 aatagaattt acatcacata tgcttcgcca cactcacgca acgcagctaa ttagggaagg
     1081 atgggatgtt gcgttcgttc aaaagagatt aggtcacgca catgttcaga caacgttaaa
     1141 tacctatgtt catctttcag atcaggatat gaaaaatgag tttaataaat acctcgagag
     1201 aaaggagcat aagaaatgaa tgcttctagt aaaaggaaaa ttattagtca gagtgagatt
     1261 agcaaaaaaa tagctgtaat gaatgaagaa atgcaggggt tttgggctaa taatagttgg
     1321 gatataagaa aatgtccaca tccttctgcc atagaattaa gtaagaatcc tgctttaagg
     1381 aatcgttggg ttcgttttga acgtgttaaa aatctgtggt taagaacaga attgaaatat
     1441 ttttattttt accatttaaa caatggaata tggaatgcaa aaactgtctg gattagaaaa
     1501 ggaacagtaa ttaataaaat gttagatttc ttagatttaa agtatcctag cattacttca
     1561 attactgaag ttcctattga aaaagcaatg acggagtata gaacttattt gacaaaacgg
     1621 ggtgttagaa ttaccactac taattataag attactgcta atcaagaaaa aacacctgta
     1681 aaagctaatt cctactatgt tactaatcta aaacaattta tggagtttta tgagaacttt
     1741 tattttgatg gagaggagtg ggataaagac gtttgggata gacgtaactt acctttgcca
     1801 gatgataagg ttaacccaac acaatatgaa tatacaatta actttaaagg gtttcggaat
     1861 acatatttta aacaacttgt aaaaagatat tgtaagttga gattgaacgt ggatagcttt
     1921 tcctatgtaa gtgatattgc ccaaagactt aaagagttct ttaattttct ggacatgaaa
     1981 tttaaacaag ttcagagagt acaccaatta acgagagtgg aaattgaagc atatttaagt
     2041 gaactaaaca tgatgggaat aaaacctagt acaataactg ggaggatctc tatattggaa
     2101 ggactattta gtacccttct taggctagaa tgggatgatg ttccttccaa aatattaatt
     2161 tattctgagg actatccgaa aataccaaga gcaaaaccac gctttataga tgaattcgtc
     2221 ctagagcaat tgaacagtca tcttgataaa ttacccgaat atatagctac gatgactatg
     2281 attgttcaag aatgtggaat gaggataagt gaattgtgca ccttgaaaaa aggctgtcta
     2341 ttagaggaca aagatggaga tttcttttta aagtattatc aatggaaaat gaaaaaggag
     2401 catatagttc caatatctaa agaggtagct ttacttatta aagttcggga agataaagtt
     2461 tcagaggaat ttccagatag tgaatacctc tttccaagaa aagatggatc gccattaaaa
     2521 caagaaacat ttagaggtga gttaaataaa ttagcttatg agcaaaatat agtggataaa
     2581 tcaggtgaga tttatagatt ccatgcccat gcctttcgcc atacagtagg aacaagaatg
     2641 attaacaacg ggatgcccca gcatattgtg cagaaatttt tggggcatga aagcccagaa
     2701 atgacaagca gatacgctca tatctttgat gaaactctaa aaaatgaatt tactaaattt
     2761 caggaaaaac tggttaccaa taatggagat gtgcttgatc tagatgaaga taatgaagtc
     2821 gatgatgtag agcttcaatg gttcaagaaa aatataaatg cacaagtgct tccaaatggt
     2881 tattgtagat tgccagtagt agcaggtggt tgtccacatg cgaatgcatg cttagattgc
     2941 actcacttct gtaccagtaa gcaattctta ccacagcacg aagaacagtt agagcgtaca
     3001 gaagagttat tagccatagc taaggataaa caatggcaaa gacaagtaga gactaatagc
     3061 cgtgttaaag agcgtttaga acaaatcatt ggaagtttga cggggtaatt atcaatggat
     3121 aaacaagtta gaaatacaac agaaattgta cgtttggcga agcagaaatc aaaaaagaca
     3181 agggaaaaag tagacaaagc gatttctaaa ttttcgattg aaggtaaagt tattaatttt
     3241 aattcaatag caaaggaagc taatgtttct aaatcatggc tttataagga acacgatatt
     3301 aggcaaagaa tcgaatccct tcgtgagcgt caaataacag caaatgtagt ctcaaaaccc
     3361 aagaaaagtt ctcgttcgga ggaaatcctt attaaaacct taaaaagaag agtaatggaa
     3421 ttagaaaaag aaaataaaaa attacagaac caaattcaaa aattatatgg agatctgtat
     3481 aataaagaat aattattaat ctgtagacaa attgtgaaag gatgtactta aacgctaacg
     3541 gtcagcttta ttgaacagta atttaagtat atgtccaatc tagggtaagt aaattgagta
     3601 tcaatataaa ctttatatga acataatcaa cgaggtgaaa tcatgagcaa tttgattaac
     3661 ggaaaaatac caaatcaagc gattcaaaca ttaaaaatcg taaaagattt atttggaagt
     3721 tcaatagttg gagtatatct atttggttca gcagtaaatg gtggtttacg cattaacagc
     3781 gatgtagatg ttctagtcgt cgtgaatcat agtttacctc aattaactcg aaaaaaacta
     3841 acagaaagac taatgactat atcaggaaag attggaaata cggattctgt tagaccactt
     3901 gaagttacgg ttataaatag gagtgaagtt gtcccttggc aatatcctcc aaaaagagaa
     3961 tttatatacg gtgagtggct caggggtgaa tttgagaatg gacaaattca ggaaccaagc
     4021 tatgatcctg atttggctat tgttttagca caagcaagaa agaatagtat ttctctattt
     4081 ggtcctgatt cttcaagtat acttgtctcc gtacctttga cagatattcg aagagcaatt
     4141 aaggattctt tgccagaact aattgagggg ataaaaggtg atgagcgtaa tgtaatttta
     4201 accctagctc gaatgtggca aacagtgact actggtgaaa ttacctcgaa agatgtcgct
     4261 gcagaatggg ctatacctct tttacctaaa gagcatgtaa ctttactgga tatagctaga
     4321 aaaggctatc ggggagagtg tgatgataag tgggaaggac tatattcaaa ggtgaaagca
     4381 ctcgttaagt atatgaaaaa ttctatagaa acttctctca attaggctaa ttttattgca
     4441 ataacaggtg cttactttta aaactactga tttattgata aatattgaac aatttttggg
     4501 aagaataaag cgtcctcttg tgaaattaga gaacgcttta ttactttaat ttagtgaaac
     4561 aatttgtaac tattgaaaat agaaagaaat tgttccttcg atagtttatt aatattagtg
     4621 acatttgcat gcttcaaagc ctgtcggaat tggtttttag tgaaaagaac acgatattca
     4681 cggtttaccc acttataaac aaaagatcga tactttttgt agtccttctt tgaaatcaat
     4741 ggttgatgtc gctcaagaac aatcaataca gagtctacac ttggcttagg atgaaaatat
     4801 agtggtggta cttttttgag catttttata tccatctcca ccattaatag taaacccaaa
     4861 gctcgttgca gattttgcaa tcttttcgca aatcccttct caacgataag atagctatat
     4921 ttagcctgac tttcaaaggt aattcttttg acaatatccg tactgatgtt ataaggaata
     4981 ttaccatata tcttatagtt tatatgtttt gggaaggaaa attttagaat atccgtttga
     5041 atcactttta tattctcaga ggggtttacc gcttctttag tcacttgaca taagcctcca
     5101 tcaatttcta tagcagtaac tgatcgactc attttgacta gctctttggt aaaatgtcct
     5161 tttcctgatc cgatttctat tacgttgtct tgtttactga tattcgtgtg attcaatatt
     5221 tcttttacat gctttttaga agtaataaaa ttttgcgtgt ctttagggtt tttctggttc
     5281 attataacct tctccttttt tttcattatg aatgagataa agtaatttct actactgcga
     5341 tactggtgca cataattgaa acctccttat gtaactgaat atgattgtat catcttttca
     5401 ttttagaata aacctttata tgtaattttg cacttgacac ttcagatgga cgttttcttc
     5461 aaaataatat gttttgaaac ttgataagag aagccactgt ctttactaaa aagtaaaggc
     5521 tgcgataaag gacagtgact ttaataaagt tgcactgttg tattgtcttt ggataaaatt
     5581 gtctaaaggg aagttttatc cccaacgaaa aaacatctaa agtggtaagt aatgaaagaa
     5641 tgtcgataaa gtaggaatgg gggatctttt tgaatacaat agaatcacag tttgataagg
     5701 ttgcagaaga ttacgatttc gtgaatgagc ttttgaatga ttattcattc tttgtgtcta
     5761 atatgtctcc aaagaaaggc agagcattag atatcggatg tggctcgggt ttgttagtgg
     5821 agaaattagc aagttattat gatgaagtgg tagggattga tatttctaat caaatgctcg
     5881 atcttgccaa a
//
LOCUS       DAPDIM010000199         5156 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.116, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000199 DAPDIM010000000
VERSION     DAPDIM010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5156
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.116"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..689)
                     /locus_tag="RFE25_002915"
     CDS             complement(<1..689)
                     /locus_tag="RFE25_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metalloprotease"
                     /protein_id="HDU2817884.1"
                     /translation="MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVL
                     VSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFET
                     SNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKK
                     HITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQ
                     LYVVFKMIFWF"
     gene            786..2795
                     /gene="mecA"
                     /locus_tag="RFE25_002916"
     CDS             786..2795
                     /gene="mecA"
                     /locus_tag="RFE25_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP2a family beta-lactam-resistant peptidoglycan
                     transpeptidase MecA"
                     /protein_id="HDU2817885.1"
                     /translation="MMKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFK
                     QVYKDSSYISKSDNGEVEMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKI
                     KTNYGNIDRNVQFNFVKEDGMWKLDWDHSVIIPGMQKDQSIHIEKLKSERGKILDRNN
                     VELANTGTAYEIGIVPKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTV
                     KKMDEYLSDFAKKFHLTTNETESRNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDD
                     AVIGKKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQ
                     KSIYNNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYGMSNEEYNKLTEDKKEPL
                     LNKFQITTSPGSTQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVV
                     NGNIDLKQAIESSDNIFFARVALELGSKKFEKGMKKLGVGEDIPSDYPFYNAQISNKN
                     LDNEILLADSGYGQGEILINPVQILSIYSALENNGNINAPHLLKDTKNKVWKKNIISK
                     ENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGTAELKMKQGETGRQIGWFISYDKD
                     NPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENGNKKYDIDE"
     gene            complement(2841..3269)
                     /locus_tag="RFE25_002917"
     CDS             complement(2841..3269)
                     /locus_tag="RFE25_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC family dehydratase"
                     /protein_id="HDU2817886.1"
                     /translation="MKYDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAE
                     QSRFKGIIASGMHTLSISFKLWVEEGKYGEEVVAGTQMNNVKFIKPVYPGNTLYVIAE
                     ITNKKSIKKENGLVTVSLSTYNENEEIVFKGEVTALINNS"
     gene            complement(3366..4109)
                     /locus_tag="RFE25_002918"
     CDS             complement(3366..4109)
                     /locus_tag="RFE25_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase"
                     /protein_id="HDU2817887.1"
                     /translation="MLTVYGHRGLPSKAPENTIASFKAASEVEGINWLELDVAITKDE
                     QLIIIHDDYLERTTNMSGEITELNYDEIKDASAGSWFGEKFKDEHLPTFDDVVKIANE
                     YNMNLNVELKGITGPNGLALSKSMVKQVEEQLTNLNQNQEVLISSFNVVLVKLAEEIM
                     PQYNRAVIFHTTSFREDWRTLLDYCNAKIVNTEDAKLTKAKVKMVKEAGYELNVWTVN
                     KPARANQLANWGVDGIFTDNADKMVHLSQ"
     gene            complement(4746..5117)
                     /locus_tag="RFE25_002919"
                     /pseudo
     CDS             complement(4746..5117)
                     /locus_tag="RFE25_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016912861.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase family
                     protein"
BASE COUNT         1838 a          824 c          768 g         1726 t
ORIGIN      
        1 ttaaaccaga atatcatttt aaaaacaaca taaagctggt tgaatattaa gtcatgactt
       61 ttcacatgtg atagttcatg tagaataata tattcaattt ctttgtcatt catggtttcg
      121 actacgacag ttggtagtac aatttgggat ttcactaaac caaataccat cggattatca
      181 atgtttgaac tataactaat tgttatatgc tttttgtaga actgcatctt actttgacat
      241 actttaagtc gttcattaag atatgacgat tccaatgacg aacttttaat aacatcaatt
      301 tgtcggaatg ccttaatcat ataaaataag cacaacaaac taccaaatac ccatatcaaa
      361 agaatcatat acgttatatt tgaggtctca aactgattaa cattaattgc taagtctttc
      421 gtaacagatg attgttgacc atctaacata tgactaaccg aagaagtcgt gtcagataca
      481 tttcgattca tcatatcttt tgaaaatgta aaattcgata ttttgtaaaa tggtattaat
      541 ggaattaacg tggagacgag cactaataac caaatcttat gtgacataat attttgagta
      601 tattttatat agagcattct cactaaaaaa attacacata tcgtgagcaa tgaactgatt
      661 atacttaaca ttaaaaaaga tgataacacc ttctacacct ccatatcaca aaaattataa
      721 cattattttg acataaatac tacatttgta atatactaca aatgtagtct tatataagga
      781 ggatattgat gaaaaagata aaaattgttc cacttatttt aatagttgta gttgtcgggt
      841 ttggtatata tttttatgct tcaaaagata aagaaattaa taatactatt gatgcaattg
      901 aagataaaaa tttcaaacaa gtttataaag atagcagtta tatttctaaa agcgataatg
      961 gtgaagtaga aatgactgaa cgtccgataa aaatatataa tagtttaggc gttaaagata
     1021 taaacattca ggatcgtaaa ataaaaaaag tatctaaaaa taaaaaacga gtagatgctc
     1081 aatataaaat taaaacaaac tacggtaaca ttgatcgcaa cgttcaattt aattttgtta
     1141 aagaagatgg tatgtggaag ttagattggg atcatagcgt cattattcca ggaatgcaga
     1201 aagaccaaag catacatatt gaaaagttaa aatcagaacg tggtaaaatt ttagaccgaa
     1261 acaatgtgga attggccaat acaggaacag catatgagat aggcatcgtt ccaaagaatg
     1321 tatctaaaaa agattataaa gcaatcgcta aagaactaag tatttctgaa gactatatca
     1381 aacaacaaat ggatcaaaat tgggtacaag atgatacctt cgttccactt aaaaccgtta
     1441 aaaaaatgga tgaatattta agtgatttcg caaaaaaatt tcatcttaca actaatgaaa
     1501 cagaaagtcg taactatcct ctaggaaaag cgacttcaca tctattaggt tatgttggtc
     1561 ccattaactc tgaagaatta aaacaaaaag aatataaagg ctataaagat gatgcagtta
     1621 ttggtaaaaa gggactcgaa aaactttacg ataaaaagct ccaacatgaa gatggctatc
     1681 gtgtcacaat cgttgacgat aatagcaata caatcgcaca tacattaata gagaaaaaga
     1741 aaaaagatgg caaagatatt caactaacta ttgatgctaa agttcaaaag agtatttata
     1801 acaacatgaa aaatgattat ggctcaggta ctgctatcca ccctcaaaca ggtgaattat
     1861 tagcacttgt aagcacacct tcatatgacg tctatccatt tatgtatggc atgagtaacg
     1921 aagaatataa taaattaacc gaagataaaa aagaacctct gctcaacaag ttccagatta
     1981 caacttcacc aggttcaact caaaaaatat taacagcaat gattgggtta aataacaaaa
     2041 cattagacga taaaacaagt tataaaatcg atggtaaagg ttggcaaaaa gataaatctt
     2101 ggggtggtta caacgttaca agatatgaag tggtaaatgg taatatcgac ttaaaacaag
     2161 caatagaatc atcagataac attttctttg ctagagtagc actcgaatta ggcagtaaga
     2221 aatttgaaaa aggcatgaaa aaactaggtg ttggtgaaga tataccaagt gattatccat
     2281 tttataatgc tcaaatttca aacaaaaatt tagataatga aatattatta gctgattcag
     2341 gttacggaca aggtgaaata ctgattaacc cagtacagat cctttcaatc tatagcgcat
     2401 tagaaaataa tggcaatatt aacgcacctc acttattaaa agacacgaaa aacaaagttt
     2461 ggaagaaaaa tattatttcc aaagaaaata tcaatctatt aactgatggt atgcaacaag
     2521 tcgtaaataa aacacataaa gaagatattt atagatctta tgcaaactta attggcaaat
     2581 ccggtactgc agaactcaaa atgaaacaag gagaaactgg cagacaaatt gggtggttta
     2641 tatcatatga taaagataat ccaaacatga tgatggctat taatgttaaa gatgtacaag
     2701 ataaaggaat ggctagctac aatgccaaaa tctcaggtaa agtgtatgat gagctatatg
     2761 agaacggtaa taaaaaatac gatatagatg aataacaaaa cagtgaagca atccgtaacg
     2821 atggttgctt cactgtttta ttatgaatta ttaataagtg ctgttacttc tcccttaaat
     2881 acaatttctt cattttcatt gtatgttgaa agtgacactg taacgagtcc attttctttt
     2941 tttatggatt tcttatttgt aatttcagcg ataacgtaca atgtattacc tgggtataca
     3001 ggtttaataa atttaacgtt attcatttgt gttcctgcta caacttcttc tccgtattta
     3061 ccttcttcta cccataattt aaatgatatt gaaagtgtat gcatgccaga tgcaatgata
     3121 cctttaaatc tactttgttc tgctttttct ttatctatat gcatatattg aggatcaaaa
     3181 gttgttgcaa attggataat ttcttcttct gtaatatgaa ggctttttgt tttgaatgtt
     3241 tctcctacta taaaatcatc gtatttcata tatgtctctc tttcttattc aaattaattt
     3301 tttagtatgt aacatgttaa aggtaagtct accgtcactg aaacgtaaga ctcacctcta
     3361 actttctatt gagacaaatg caccatttta tctgcattgt ctgtaaagat accatcaact
     3421 ccccaattag caagttggtt tgcacgtgct ggtttgttta cagtccatac gttcaattca
     3481 taacccgctt cttttaccat ttttactttt gctttagtaa gtttggcatc ttcagtgttt
     3541 actattttag cattacagta atctaaaagt gttctccagt cttcacgaaa cgaagttgta
     3601 tggaatataa ctgctctgtt atattgtggc atgatttctt ctgcaagttt aacaagcaca
     3661 acattaaagc ttgaaatgag cacttcttga ttctgattta agtttgttaa ttgttcttcc
     3721 acttgcttaa ccatactttt agaaagtgct agtccattcg gtccagtaat accttttaat
     3781 tctacattta aattcatatt atattcattt gctattttta ctacatcatc gaaagttggc
     3841 aaatgttcat ctttgaattt ttcaccaaac caagatcctg cagaagcatc tttaatttca
     3901 tcataattca attcagttat ttccccggac atatttgtag tccgttctaa ataatcatca
     3961 tgaatgataa tcagttgttc atcttttgta attgcaacat ctaactccaa ccagtttata
     4021 ccttctactt ctgaagcagc tttaaatgat gcaattgtat tttccggagc tttactaggt
     4081 aatcctctat gtccatatac agttagcata ttacctctcc ttgcattttt atttttttaa
     4141 ttaacgtaac tgtattatca cattaatcgc acttttattt ccattaaaaa gagatgaata
     4201 tcataaataa agaagtcgat agattcgtat tgattatgga gttaatctac gtctcatctc
     4261 atttttaaaa aatcatttat gtcccaagct ccattttgta atcaagtcta gtttttctgt
     4321 accccttatc tgcaatttta cttaggattg cttttaactt accccttatc agcaatttta
     4381 ctgagaactg cttttaacgc acctcttatc tgcaattttg cctagaactg cttttaacgt
     4441 acctcttatc tgcaatttta cttagaattg cttttactat tcctcttatt agtataatct
     4501 cagtaagaat gcgtataaaa atgaaaatta caaccgattt tgtaagtgct gacgcctgag
     4561 ggaatagtat gtgcgagaga ctaatggctc gagccatacc cctaggcaag catgcacgta
     4621 caaaatcgta agataaaaaa ataagcatat cactgtaaac tttaaaaaat cagtttagtg
     4681 atatgcttat ttatttcgag ttaggattta tgtcccaagc tcatcaagca caatcggcca
     4741 ctagtttatt tctctatctt atatgttctg atatggtctt ctatactgta taagtatact
     4801 tttgaatatg gatcttgtgt caattcacgt tcgaaatcaa attcttgatt atcaaatctg
     4861 ttaaagaatg tttcgtattc ttcgactgat aattgctctc tagattctag catatttaag
     4921 tgtttctctt tatctaatgc tttgtcatat cctttaacga ttgaaccact aaagatttct
     4981 cctactgctc ctgaaccata actaaataga catactttct cttctggttg gaatgtgtgg
     5041 ttctgtaata acgaaattaa acttaagtat aatgatcctg tataaatgtt accaacatct
     5101 ctattccata atacggttct gttgcaaagt tgaatttata gtataatttt aacaaa
//
LOCUS       DAPDIM010000200         4999 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.118, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000200 DAPDIM010000000
VERSION     DAPDIM010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4999
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.118"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            127..546
                     /locus_tag="RFE25_002920"
     CDS             127..546
                     /locus_tag="RFE25_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FosB1/FosB3 family fosfomycin resistance
                     bacillithiol transferase"
                     /protein_id="HDU2817888.1"
                     /translation="MLKSINHICFSVRNLNDSIHFYRDILLGKLLLTGKKTAYFELAG
                     LWIALNEEKDIPRNEIHFSYTHIAFTIDDSEFKYWHQRLKDNNVNILEGRVRDIRDRQ
                     SIYFTDPDGHKLELHTGTLENRLNYYKEAKPHMTFYK"
     gene            complement(802..1737)
                     /locus_tag="RFE25_002921"
     CDS             complement(802..1737)
                     /locus_tag="RFE25_002921"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HDU2817889.1"
                     /translation="MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSMPS
                     GVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEEL
                     IDTQKEFAMLAAKSIANHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDT
                     RAEQQSTSGTSFRQILEEDENTDYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLSH
                     VSPTIKDMIERFVHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIP
                     SDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK"
     gene            2027..3286
                     /gene="sdpC"
                     /locus_tag="RFE25_002922"
     CDS             2027..3286
                     /gene="sdpC"
                     /locus_tag="RFE25_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease SdpC"
                     /protein_id="HDU2817890.1"
                     /translation="MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSIIGVKHFIFE
                     VTDLAPLIAAIICILVFKYKKVQLAGLKFSISLKVIERLLLALILPLIILIIGMYSFN
                     TFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVG
                     LMYSVFSANTTYGTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLI
                     FLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIAYLTTRRNLEELEPNNYLDHV
                     NDDEETNHTEAEKSSSNIKDAEKTGVATASTVGVAKNDTENTVADEPSIHEGTEKTEP
                     QHHIGNQTESNHDEDHDITSESVESAESVKQAPQSDDLTNDSNEDEIEQSLKEPATYK
                     EDRRSSVVIDAEKHIEKTEEQSSDKNK"
     gene            complement(3352..4038)
                     /locus_tag="RFE25_002923"
     CDS             complement(3352..4038)
                     /locus_tag="RFE25_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase A"
                     /protein_id="HDU2817891.1"
                     /translation="MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLI
                     KERGYNITGVCTSNKIAFLAKELGIKICEINDVDHIDLAIDGADEVDPSLNIIKGGGG
                     ALFREKVIDEMASRFVVVVDETKIVQYLGETFKLPVEVDKFNWYHILRKIESYADIKV
                     ERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVG
                     TQEGVKILEK"
     gene            4212..4865
                     /locus_tag="RFE25_002924"
     CDS             4212..4865
                     /locus_tag="RFE25_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDU2817892.1"
                     /translation="MISIHAISTGKIQDLPYSSKRPIRSALDKTKISQTTWLSSTGFT
                     GDEQAYKDHGGPHKAVCGFSKHNYALYQDDLPTLPTHAMFGENLTFDYLDESDVYFGN
                     QYRLGEALIEVSEIREPCWKIQAKYNIPDLVKRMSTSGKTGFYFRVLKQGYVSPNDQL
                     YLIQEAPIEHRLSVQQLNDLYYNDRQNQDMLRYALNNPFLSPTRRDKLQKMYNRTLK"
BASE COUNT         1723 a          891 c          709 g         1676 t
ORIGIN      
        1 tttaacttaa gttattagag cctcttatgc agttgctcag atcatcgtat aaaaattaat
       61 gacgtcattt caaaaatcga tacaaaaata atttattata aaaattctaa gaaagaagtg
      121 aagcagatgt taaaatctat taatcatata tgcttttcag tcagaaattt aaacgattca
      181 atacattttt atagagatat tttacttggg aaattgctat tgactggtaa aaaaactgct
      241 tattttgagc ttgcaggcct atggattgct ttaaatgaag aaaaagatat accacgtaat
      301 gaaattcact tttcatatac acatatagct ttcactatag atgacagcga atttaaatat
      361 tggcatcaga ggttaaaaga taataacgtg aatattttag aaggaagagt tagagatatt
      421 agagatagac aatcaattta ctttactgac cctgatggtc ataagctaga attacatact
      481 ggcacacttg agaacagatt aaattattat aaagaggcta aaccacatat gacattttac
      541 aaataaggcg tcattataaa aaggcctctt gaaatccgtt aaaattttaa ttaattatta
      601 tataataaga gaacttttca aacaatacag ttgttatttt tgctatttca acaaacataa
      661 ataagcagta agatgactac aacttaagag tcttcttact gcaattattt ttcaaatata
      721 tcaacgttaa tataacttct attaagaaat actcacattc tgccctgcaa tgcaaatctc
      781 gtcacatata aatattttta attattttaa aaaatgatgc actaaattag caacgagctt
      841 agcagttcta ttgtcagcgt catatgttgg attcatctca gcaatactaa ctgaagacac
      901 cttatcactt ggaataatac gttttgctaa ttcaagaaca gtatgtggat acaaacctaa
      961 cactgccggc gcacttaccc caggcgcaaa cgcactatca atgacatcca tacaaatcgt
     1021 aaacataatg acatcatgtt catgtacaaa acgttcaatc atatctttaa ttgttggtga
     1081 tacgtgactc aataattcat ctgcaaagac ataatcaatc tttttctctt tagcataatc
     1141 aaataaactt tgcgtattac caccttgagc aataccaagc actaaataat ctgtgttttc
     1201 atcttcttct aaaatttgtc taaagctcgt tccagatgta gattgttgtt cagcacgtgt
     1261 atcaaaatgc gcatcaatat ttatcacacc aatagattgt gttggataga ctttacgtgt
     1321 tgctaaatat tgagcatacg caatatcatg tccaccacct aataaaaatg tttgtctatg
     1381 attagcaatt gacttcgctg caagcatagc aaattctttt tgagtatcaa ttaattcctc
     1441 atgatcatga taaacatttc cgtaatcgac taaagtttca cattgattca aatccggcaa
     1501 acctgcaaat gcttgtttaa tcgcatctgg tccttctttt gcaccaatgc gccccttgtt
     1561 taaagcaaca cctttgtcaa cagcatagcc taatataccg acccctgatg gcatactact
     1621 cttttccagc ttagacaaat cttcaaatgt tactgtttga aaatgtctaa attttttcgg
     1681 gtctgtttca ctatctaacc ttccagtcca taaatttggt tcaccttgct tgtacacagc
     1741 atttccccct cttatttatg tggcttatta acaattaaag tataacgtat aggaaatttt
     1801 gaattcaatt catagttaaa tccgtatctt aaaaatactt atctacatta cttttacccc
     1861 tattttctat gtaataacga atacttagct gatttatgtt aataaaatac gtcaagacta
     1921 ttacattttc attaatattg acatagacaa tttatctctc ggcttgtaat atgtataatt
     1981 gttactaaaa gatattttgc ttgttaccta atggaggtta catataatga agaacaataa
     2041 aatttctggt tttcaatggg caatgacgat tttcgtcttc tttgtcatta caatggcgtt
     2101 atccattatg ctcagagatt tccagtctat aattggtgtc aaacacttta tatttgaagt
     2161 tacagatcta gcaccattaa ttgctgcaat catttgtata ctcgttttca aatataaaaa
     2221 ggtccaactt gcaggtttaa aattctcaat cagcctgaaa gtaattgaac gtctattgct
     2281 agctttaatt ttacctttaa ttattctaat tattggtatg tacagcttta atacatttgc
     2341 agatagcttt attttattac aatcaacagg cttatcagta cctattacac acattctgat
     2401 tggacatatt ctgatggcgt tcgtagtaga attcggattc cgttcatact tacaaaatat
     2461 tgttgaaacg aaaatgaaca cgttctttgc aagtattgtt gttggtttga tgtattcagt
     2521 tttctcagca aatacaactt atggtacaga atttgctgct tataacttcc tttatacatt
     2581 ctcattctct atgattcttg gtgaattaat tagagcgact aaaggacgta caatttatat
     2641 tgcaacgaca ttccatgctt caatgacatt cggacttatt ttcttgttta gcgaagaaat
     2701 cggcgatcta ttttcaatca aagtcatcgc catttcaaca gcaatcgttg cagtaggata
     2761 cattggttta agcttaatta tccgaggtat tgcatattta acaacaagac gaaaccttga
     2821 agaacttgag cctaataatt atttagacca tgtcaatgac gatgaagaaa ctaatcatac
     2881 tgaggctgaa aaatcttctt caaatattaa agatgctgaa aaaacaggtg tagctactgc
     2941 atcaacggtt ggtgttgcta aaaatgatac tgaaaataca gtggctgacg aaccaagcat
     3001 tcatgaaggt actgaaaaaa cagaacctca acatcacata ggtaatcaaa ctgaatctaa
     3061 tcatgatgaa gatcatgaca tcacttcgga gtcagtagaa tcagcagaat cagttaaaca
     3121 agcaccacaa agtgacgatt taacaaacga ttcaaatgaa gatgaaatag agcaatcatt
     3181 aaaagaacct gcgacttata aagaagacag acgttcatca gttgtaattg atgcagaaaa
     3241 acatatcgaa aaaactgaag aacaatcttc agataaaaac aaataataac aaagcgcttg
     3301 ctagtacctc ttaaaaagat gatgctagca agcgcttttc tatactatat attatttttc
     3361 taaaatttta acaccctctt gagtgcctac aataacttga tctgccatat ctaagaagta
     3421 tcctgtctca aacacacctg tcagatgaat taaatactca tggaacttat atgggtcaat
     3481 tccttttggt aacttacaat ctaaaatata attgccatta tcagttataa atgcgacatc
     3541 ttcgtttaca cgacgttcta cttttatatc agcgtatgat tcaattttac gtaatatgtg
     3601 ataccagtta aatttatcca cctctactgg taacttaaac gtctcaccta agtattgaac
     3661 tattttcgtt tcatcgacaa ccacaacaaa acgcgatgcc atttcatcta taactttctc
     3721 tctgaacagc gcaccaccgc cacctttaat tatatttaaa gatggatcta cttcatcagc
     3781 accatcaatt gctaagtcga tatgatcaac atcattgatt tcacatattt taatacctaa
     3841 ttcttttgct aaaaatgcaa ttttattaga agtgcataca cctgtaatat tgtaaccacg
     3901 ttctttaatt agttgcgcca tttgaggtaa gagtaattcc attgtacttc ctgtaccaat
     3961 tcccagcgtc atgtcaccat tgatttgact taaaacatca tttaatgtca ttaacttgag
     4021 tgctttgaca tctttcatga aggtagcctc ccatatttat gtaatctatt caattcatat
     4081 tttacatgac tcgtataaat taacataccc ttatttctaa cattttttta aacatatcaa
     4141 tcagaattta caattctaaa aatgttttat agtacaatat attttaaata atactcgtta
     4201 aggagaatga tatgatatca attcacgcaa tttcgacagg aaaaatccaa gatttgcctt
     4261 atagctcgaa aagaccgata cgctctgctt tagataaaac taagatttca caaacaacat
     4321 ggttatcttc aactggtttc actggtgatg aacaggctta taaagatcat ggtggaccac
     4381 ataaagcagt ttgtgggttt agtaagcata attatgcact gtatcaagat gatttaccta
     4441 cactacctac tcatgcgatg tttggagaga atttaacatt tgattattta gacgaatctg
     4501 atgtttactt tggtaatcaa tatcgtttag gtgaagcgtt aattgaggtt tctgaaatta
     4561 gagaaccatg ctggaaaatt caagcaaaat ataatattcc tgatttagtg aagcgcatgt
     4621 ctacatctgg taaaacaggt ttctatttcc gggtattaaa acaaggctat gtatctccaa
     4681 atgatcagct ttacttaata caagaagcac caatcgaaca tcgtttatct gtacaacagc
     4741 ttaatgacct ttattataat gatagacaaa atcaagatat gttacgatat gcactaaaca
     4801 atccatttct gtcaccaaca agacgcgata aacttcaaaa aatgtataac agaacattga
     4861 aataattacc tttcattata agtgttaaat gaacttttca aaacaaaaag gaatcaactt
     4921 acacatcgtt tgtataatag tcttatctat aaccactgat gctattgatt ccttttttat
     4981 gttatatatt ttctttatt
//
LOCUS       DAPDIM010000201         4726 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.123, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000201 DAPDIM010000000
VERSION     DAPDIM010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4726
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.123"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            9..587
                     /locus_tag="RFE25_002925"
     CDS             9..587
                     /locus_tag="RFE25_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDU2817893.1"
                     /translation="MKIGYARVSTGLQNLNLQEDQLNQYGCEKIFSDHISGSKSKRPG
                     LDKAIEFARAGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSST
                     GQLLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLKLLKTLYDNG
                     TPIKTIAEQWKVSRTTIYRYLNRLNNQENKDK"
     gene            713..1321
                     /locus_tag="RFE25_002926"
     CDS             713..1321
                     /locus_tag="RFE25_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDU2817894.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRP
                     VFQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGN
                     PLLDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQ
                     KRVIYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
     gene            1567..1905
                     /locus_tag="RFE25_002927"
     CDS             1567..1905
                     /locus_tag="RFE25_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817895.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRK
                     MFIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYY
                     TTNKKYTSKG"
     gene            1910..2095
                     /locus_tag="RFE25_002928"
     CDS             1910..2095
                     /locus_tag="RFE25_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDU2817896.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTL
                     AFKLARLFDTTVDELFS"
     gene            complement(2228..2794)
                     /gene="qacR"
                     /locus_tag="RFE25_002929"
     CDS             complement(2228..2794)
                     /gene="qacR"
                     /locus_tag="RFE25_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001807342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug-binding transcriptional regulator
                     QacR"
                     /protein_id="HDU2817897.1"
                     /translation="MNLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFK
                     TKENLFLEILNIEESKWQEQWKKEQIKCKTNREKFYLYNELSLTTEYYYPLQNAIIEF
                     YTEYYKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWCINDVNAVSKIAANAVNGIV
                     TFTHEQNINERIKLMNKFSQIFLNGLSK"
     gene            2972..4516
                     /locus_tag="RFE25_002930"
     CDS             2972..4516
                     /locus_tag="RFE25_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /protein_id="HDU2817898.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPE
                     LVRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIF
                     FAESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFG
                     PIIGGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIA
                     GMIGLVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSF
                     SAGTIAAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLA
                     ARFGPKIVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGMASLAVASALIML
                     ETPTSKAGNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHV
                     AEESVVGAVEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSL
                     DITKQK"
BASE COUNT         1642 a          623 c          805 g         1656 t
ORIGIN      
        1 tttgtatttt gaaaataggt tatgcaagag tttcaactgg tttacaaaat ttaaatttgc
       61 aggaagatca attaaatcaa tatggttgtg aaaagatatt tagcgaccac ataagtggat
      121 caaaaagtaa acgtcctggt ttagataaag ccattgaatt tgcgagggca ggagatacga
      181 ttgttgtttg gagactagat agactagggc gtaatatgga agatttaatc acattagtta
      241 atgaacttaa taatcgaggc gtgagttttc atagtttaga agaaaatata acaatggata
      301 aatcaagttc tacaggacaa ttgttatttc atttattcgc agcatttgca gagtttgaac
      361 gcaacttaat tttagaacgt tcttcagcag gacgaattgc cgctcgtgct agaggacgct
      421 atggaggtcg tcccgaaaaa ttaaataaac aagatttaaa gttactcaaa acactttatg
      481 ataatggaac accaattaaa actattgcag aacaatggaa agtttcacgt accacaatct
      541 atcgttatct caataggtta aataatcaag aaaataaaga taaataatat tactaagttt
      601 taagaaagat aaaaatagac aggacacacc ctaaccatac aaaaagaatt gttgaaatta
      661 taacaattaa aacgtatgat tagggtgtat atttattatg gagtgaagat gaatgattat
      721 aggttatgcg agagtatcat cgatagatca aaatttagaa agacaattgg ataatttaaa
      781 gacgtttggt gtggagaaaa tctttacaga gaaacagtcg ggaaagtcag tggaaaatag
      841 acctgtattt caagaagcac tcaattttgt cagaatggga gatcgattcg ttgtggaatc
      901 tattgatcgt ttaggacgta actatgatga aattattgaa actgtgaatt atttaaaaga
      961 aaaagacgtt cagttaatga ttaccagctt acctatgatg aatgaagtaa ttggcaatcc
     1021 attactggat aagtttatga aagatttaat cattcaaata ttagcaatgg tttcagaaca
     1081 agagagaaat gaaagtaaac gtcgacaagc gcaagggatt caagttgcga aggaaaaagg
     1141 cgtatataaa gggcgccctt tactttattc accaaatgct aaagacccac agaaacgtgt
     1201 tatttatcat cgcgtggtgg aaatgttaga agaaggcaaa gcgattagta agattgcgaa
     1261 agaagttaat atcacaagac aaacagttta tagaattaaa catgataagg gattatcttg
     1321 ataaattgat tgtcaatgca aatgagcgtc tctcacagtg tctcaaattc cataacatat
     1381 tattgaattg agattttaat aattatacaa gaaaaaagag tacgagttcg cagctttcta
     1441 tatagtaatt gttttactaa taaggtgttt taaaatatat tataatgtaa aaagtatttg
     1501 acatttgtat caaaaatatt tacactcata aatgtcaaat actttttaca tttatgaggt
     1561 gttataatga atttaattcc ttttattatt attttaattt tttcttgttt atggacggct
     1621 ataactaaca aatatttacc ttcagaaaca ttagataaaa aaggacaaca agatcgatac
     1681 gatgaaagac aacgtaaaat gtttattgaa atactggcta aaagttttat ttggattgta
     1741 tattgtatgt tatttacact agtgcttaaa tttacaggtt tgtcaccaag tattgaagga
     1801 tcttggtttt ctcaatatcc agaaattttc tttataattg tagcactatt tcttatgctg
     1861 tttaattact atactacaaa taaaaaatat acatctaaag gttaaattaa tgaaaaatag
     1921 aattagagaa tatagaaaac aaaaaggaat ttctcaagaa actttaagta aagaattaaa
     1981 agtgtctagg caaactatta atgcaataga aaacaataaa tatgatccta cattgacatt
     2041 agcatttaag ttggcaagat tgtttgatac aactgtggat gaattatttt cttaaccatt
     2101 catttatcac aaaaagagag tgcgaattcg cactctcttt ttgtgtagta gtactattaa
     2161 attttgtctc aataacgaac gtaatttaga aataatattt attggtattt caagaatata
     2221 tatataatta tttactaagt ccatttaaaa aaatttgaga gaacttgttc ataagtttaa
     2281 ttctttcatt aatattttgt tcatgtgtaa aggtaacaat tccattaaca gcgtttgctg
     2341 ctattttact aacagcatta acatcattaa tacaccattc gccatttaaa ttaccctcct
     2401 taaaaattac atgataagca tctatatatt tgttttctaa tttattcatt ttttcattaa
     2461 tgctattagt tttataatat tcagtgtaaa attcaattat tgcgttttga agtggataat
     2521 agtattcggt tgttaaagat agttcattat ataaataaaa tttttctcta ttagttttac
     2581 atttgatttg ttcctttttc cactgttctt gccatttaga ttcttctata tttaaaattt
     2641 ctaaaaatag attttctttt gttttaaagt gataataaag attcccttta ctactttctg
     2701 ataatttaac aatttctcca gtagtagtgg cattatatcc attttttata aataattcct
     2761 ttgcgacacc tagtatttta tctttcaagt tcatcacgcc tttaatgagt attaagtact
     2821 atcaatgata gcacaaaaaa ttcaaagaat aattgtataa cacaatacag ccatttaaat
     2881 ttcgcaagat tttttgttgt aatatgtaaa aaaatagatt ataatcctta tagaccgatc
     2941 gaacggtcta taaggattgg agggaactta aatgatttca ttttttacaa aaactactga
     3001 tatgatgaca tcaaaaaaaa gatggactgc actagtagta ttagctgtta gtttgtttgt
     3061 tgttacaatg gatatgacaa tattaattat ggctttaccg gaattagtaa gagagttaga
     3121 gccttctggt acccaacagt tatggatagt tgatatatac tctcttgttt tagctggctt
     3181 tataattcca ttgagtgcct ttgctgataa atggggaaga aaaaaagcat tattaactgg
     3241 atttgcttta tttggcctcg tttcattagc tatatttttc gcagaaagtg cagagttcgt
     3301 aatagctatt cgatttttac ttggtattgc aggtgcttta ataatgccaa ctactctttc
     3361 aatgataaga gtaatttttg aaaaccctaa agaaagggcc actgcattag ctgtatggtc
     3421 aatcgcttca tcgataggtg ctgtttttgg accaattatc ggaggagctt tacttgagca
     3481 attttcatgg cactcggcat ttttaattaa tgtaccgttt gcgataatag cagttgtagc
     3541 aggtttattt ttattaccag agtctaagtt atcaaaagaa aagtctcact cgtgggatat
     3601 tccttctaca attttatcaa ttgcaggcat gattggactg gtatggagta tcaaagaatt
     3661 ttcaaaagaa ggactagcag atattattcc atgggttgta atagtattag caattaccat
     3721 gatagtgata tttgttaaac gtaatttatc aagttctgat ccaatgttag acgtaagact
     3781 ttttaaaaag agatcatttt cagctggtac aattgctgca tttatgacaa tgtttgcaat
     3841 ggcatctgtt ttgttattag cttcacaatg gttacaggtt gtggaagaac tttctccttt
     3901 taaagctggc ttatacctat tacctatggc aataggagat atggtgtttg caccaattgc
     3961 acccggatta gcggcgcgat ttggaccgaa aatagtgtta ccttccggaa ttggaattgc
     4021 agccattggc atgtttatta tgtatttctt tggtcatcca ttatcatatt ctacaatggc
     4081 tttagcatta attttagttg gagctggtat ggcttcacta gcagttgcat ctgctctaat
     4141 aatgttagaa acacctacat caaaagcagg taatgcagct gctgttgaag agtctatgta
     4201 tgaccttgga aatgtttttg gtgtagcagt acttggtagc ctatcttcta tgctttatcg
     4261 tgtattttta gatatttcat ctttttcatc aaaaggtata gttggagatt tagctcatgt
     4321 agctgaagaa tctgtagtgg gcgctgtcga agtagctaaa gctacgggga taaaacagct
     4381 tgcaaacgag gctgtaacat catttaatga tgcttttgta gcaactgctt tagtaggtgg
     4441 gattatcatg attatcattt caatagttgt ctatttgtta attcccaaat cacttgatat
     4501 aactaaacaa aaatagtact aaacatatat ttttagatat tgtagattag tttattttta
     4561 aaattagtaa tagttaaaaa gtagaaccat taattttaaa tggttctact tttttattat
     4621 taagtaaaat tataaaagac aatttcttaa attaataata tgatatacct atatctaata
     4681 atttattagt attaataaac cttgaaagga tgattaactg atgaat
//
LOCUS       DAPDIM010000202         4508 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.125, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000202 DAPDIM010000000
VERSION     DAPDIM010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4508
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.125"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            complement(<1..176)
                     /locus_tag="RFE25_002931"
     CDS             complement(<1..176)
                     /locus_tag="RFE25_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDU2817899.1"
                     /translation="MMKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFK
                     QVYKDSSYISKSDNG"
     gene            273..1259
                     /locus_tag="RFE25_002932"
     CDS             273..1259
                     /locus_tag="RFE25_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer MecR1"
                     /protein_id="HDU2817900.1"
                     /translation="MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVL
                     VSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFET
                     SNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKK
                     HITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQ
                     LYVVFKMIFWFNPALYISKTMMDNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKS
                     QHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISSFT"
     gene            1231..1491
                     /locus_tag="RFE25_002933"
     CDS             1231..1491
                     /locus_tag="RFE25_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3387 domain-containing protein"
                     /protein_id="HDU2817901.1"
                     /translation="MYVVYRASHETAKEALGDKELRAIAHELTKTVKDNMSVDWSKRD
                     SAKAKMRVQVRRLLKKYGYPPDLQKMAVEQVVEQAELMASQQ"
     gene            complement(1482..3089)
                     /locus_tag="RFE25_002934"
                     /pseudo
     CDS             complement(1482..3089)
                     /locus_tag="RFE25_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274780.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(3141..3647)
                     /locus_tag="RFE25_002935"
     CDS             complement(3141..3647)
                     /locus_tag="RFE25_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HDU2817902.1"
                     /translation="MNTIKSTINTEAIFSDDEQHRYLLKKTWDEKKPACTVITMYPHL
                     DGVLSLDLTTVLILNQLANTEQYGAVYLVNLFSNIRTPENLKHIKNPYDEHTDIHLMK
                     AISESDTVILAYGAYAKRPVVIDRVEQVMEMLKPHKKKVKKLINPVTNEIMHPLNPKA
                     RQKWILKS"
     gene            complement(3662..3973)
                     /locus_tag="RFE25_002936"
     CDS             complement(3662..3973)
                     /locus_tag="RFE25_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817903.1"
                     /translation="MNINRYITRGISEHLSLDLQILLWNMVKERDNQPDTDYLHIFRL
                     KEDENILSIIHEQEQPTYKLEYHYTNYIKNQNALPKKVYVIREDDVDVFYYVMLLPEE
                     Y"
     gene            complement(4060..4410)
                     /locus_tag="RFE25_002937"
     CDS             complement(4060..4410)
                     /locus_tag="RFE25_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002502216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDU2817904.1"
                     /translation="MKTTTQELKQYITRLFQLSNNETWECEALEEAAENILPTRFVDH
                     TPLAHLTLDTYTYYNDELHELSIYPFLMYTNNQLISIGYLDHFDMDFLYLTDTKNTII
                     DERHLLKEGGTRHE"
BASE COUNT         1386 a          668 c          721 g         1733 t
ORIGIN      
        1 ccattatcgc ttttagaaat ataactgcta tctttataaa cttgtttgaa atttttatct
       61 tcaattgcat caatagtatt attaatttct ttatcttttg aagcataaaa atatatacca
      121 aacccgacaa ctacaactat taaaataagt ggaacaattt ttatcttttt catcaatatc
      181 ctccttatat aagactacat ttgtagtata ttacaaatgt agtatttatg tcaaaataat
      241 gttataattt ttgtgatatg gaggtgtaga aggtgttatc atctttttta atgttaagta
      301 taatcagttc attgctcacg atatgtgtaa tttttttagt gagaatgctc tatataaaat
      361 atactcaaaa tattatgtca cataagattt ggttattagt gctcgtctcc acgttaattc
      421 cattaatacc attttacaaa atatcgaatt ttacattttc aaaagatatg atgaatcgaa
      481 atgtatctga cacgacttct tcggttagtc atatgttaga tggtcaacaa tcatctgtta
      541 cgaaagactt agcaattaat gttaatcagt ttgagacctc aaatataacg tatatgattc
      601 ttttgatatg ggtatttggt agtttgttgt gcttatttta tatgattaag gcattccgac
      661 aaattgatgt tattaaaagt tcgtcattgg aatcgtcata tcttaatgaa cgacttaaag
      721 tatgtcaaag taagatgcag ttctacaaaa agcatataac aattagttat agttcaaaca
      781 ttgataatcc gatggtattt ggtttagtga aatcccaaat tgtactacca actgtcgtag
      841 tcgaaaccat gaatgacaaa gaaattgaat atattattct acatgaacta tcacatgtga
      901 aaagtcatga cttaatattc aaccagcttt atgttgtttt taaaatgata ttctggttta
      961 atcctgcact atatataagt aaaacaatga tggacaatga ctgtgaaaaa gtatgtgata
     1021 gaaacgtttt aaaaattttg aatcgccatg aacatatacg ttatggtgaa tcgatattaa
     1081 aatgctctat tttaaaatct cagcacataa ataatgtggc agcacaatat ttactaggtt
     1141 ttaattcaaa tattaaagaa cgtgttaagt atattgcact ttatgattca atgcctaaac
     1201 ctaatcgaaa caagcgtatt gttgcgtata ttgtatgtag tatatcgagc ttcacatgaa
     1261 acagctaaag aagctttggg cgataaagag ttaagagcca ttgcacatga gttaactaaa
     1321 acagttaagg ataacatgag tgttgattgg tctaaacgag acagtgctaa agctaaaatg
     1381 agagttcaag ttagacgcct attaaagaaa tatggctatc caccagatct tcaaaaaatg
     1441 gctgtggaac aagttgtaga gcaagcagaa ttaatggcaa gtcagcaata aaaaaataaa
     1501 tcataatgag tccgggacat aaagttcttg gataagtgaa aaaagacaat ttctattgaa
     1561 ataatataga aattgtcttt tttataaatt ttttgattat tttcagctcg ttgagctact
     1621 acttttctta tattaagtgc cattaataca aaaccaagtt ctcttttgac tttattgagt
     1681 cctcggacag acatccgagt gaaacccaaa atagccttca taaatccaaa aacaggttcc
     1741 acatcaattt ttctttgatt gtagatattt tttgtttctg gttctgaaag ctttttgtta
     1801 atttgggatt taaaatattc ccagttataa ttcttcatta tttttttgtt tgtttttgaa
     1861 ttgaagttca tacattgatt tttcagagga cattctgaac aatcatcaca ttcatataat
     1921 ttgaagtctc gcttataacc atacttatca tgacgatagg catatctttt aaaacctagc
     1981 cgtttattat tcggacaaat gaattcgtca ttaatttcgt catagttcca attttgagta
     2041 ttaaagatgt cacttttata ttttttagtt ttatctttta taaacattcc atatgttatg
     2101 agtggcgttc gattaaagtc atctataatt gccttataat ttgattcact accataacct
     2161 gcatcagcta caatatattc aggtaaatga ccgtaggtct cttgaattga atttaaaaat
     2221 ggaatcatcg ttctagtatc cgttggattt tgatacacat tataagataa aacaaattgg
     2281 gaatttgttg ctatttgtaa attataccct ggcttaagtt gtccattttt catgtgatct
     2341 tctttcattc tcataaatgt cgcatcataa tctgtcttag aataactatt tctatccttt
     2401 aaaatagatt tttgaaattc gtatcgatac tttcgctcaa aataatcatt gatttgcttt
     2461 ttgtattttt tgattttagt tcttttgaga cgtatttgtt ttcttgtttt agtacatttt
     2521 tcattgttga tatgttggtt taaatcttcg atttctttat ctaagtgact accaatcaaa
     2581 tctatttctt cttttgttaa ttcattatca tgatcttctt taatttccgg tatgatttta
     2641 ttggttacca attcatggta gagggcttta gaatcctcat tcatctttga ttcatggttt
     2701 tgaatactct ttttccatac aaatgtatat cgattggcat ttgcttcaat ttttgtacca
     2761 tcaataaaaa tagctttatc atctataaga ttttgtttta cacactgact gtaaaattga
     2821 ataaataaag attctaataa agcatctact tttggattta ctctaaattg attaattgtt
     2881 ttataagaag gtttttgatt ttgtgatagc cacatcattc ggatgctatc attaagcatt
     2941 ttttctattt tacgacctga gaatacagat tgtgtgtagg catatagaat cacttttaac
     3001 atcattttag gatggtacga agttgcacca cggtgatgtc tgaattcgtc gaattcattg
     3061 tcaggaattg tttcaacaat atcatttaca gtaaaacgat gttgatttgt tttgtttcca
     3121 tattgacctc catgtatttg ctatgatttc aaaatccatt tttgacgtgc cttagggttg
     3181 agtggatgca taatttcatt tgttactgga ttgatgagct tttttacttt ctttttatga
     3241 ggttttaaca tttccatcac ttgttcgaca cggtcgataa caactggtcg cttcgcatag
     3301 gcaccataag caagaatcac tgtgtcactt tcactaatcg ctttcatcaa atgaatatca
     3361 gtgtgctcat cgtatggatt tttgatatgt ttgaggtttt cgggtgttct aatatttgaa
     3421 aatagattta caagatatac agcaccatat tgttcagtat tagctaattg attgaggata
     3481 agaacagttg tgagatcgag tgataataca ccatctaaat gagggtacat cgttatcact
     3541 gtacaagcgg gtttcttttc atcccatgtt ttcttgagta aatagcggtg ttgttcatca
     3601 tcgctaaata tggcttctgt gtttatcgta cttttgattg tattcatcat cgtcactcct
     3661 tttagtattc ttctggtaaa agcatcacat aataaaaaac atctacatca tcttctcgga
     3721 tgacgtagac tttcttaggt aatgcatttt gattttttat atagtttgta tagtgatatt
     3781 ccaatttgta cgtgggttgt tcttgctcat gtatgattga aagtatattc tcatcttctt
     3841 tcagtctaaa aatgtgtagg taatctgtat caggttgatt atctctttct tttaccatgt
     3901 tccaaagtaa gatttgaaga tctagagata ggtgttcact aatgcctctt gtgatatatc
     3961 gattgatgtt catactattt tcctccattt tgcttttctt tcatgatgtc aatcacttcg
     4021 ttaatgactg taacagatat ttgtgccact ttgatccaat tattcatggc gagtccctcc
     4081 ttcttttagt agatgacgtt catcgataat cgtattttta gtatctgtga gatataaaaa
     4141 gtccatgtca aaatgatcca gataaccgat actgatgagt tggttattgg tgtacattag
     4201 aaatggatag atacttagct catgtagctc atcattatag taggtataag tgtcaagtgt
     4261 aagatgcgca agtggggtat ggtctacaaa gcgagtagga agtatatttt ctgctgcttc
     4321 ttctaacgct tcacattccc atgtttcatt gttagatagt tggaatagac gagttatata
     4381 ttgtttgagt tcttgagtgg ttgttttcat atcattgcct cctagatagt gttagcgatg
     4441 tatttcatat acatcactga gataatatat atttgattta tcatttatta cgaatcccgg
     4501 tgggaata
//
LOCUS       DAPDIM010000203         2460 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.138, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000203 DAPDIM010000000
VERSION     DAPDIM010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2460
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.138"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            253..960
                     /gene="deoD"
                     /locus_tag="RFE25_002938"
     CDS             253..960
                     /gene="deoD"
                     /locus_tag="RFE25_002938"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDU2817905.1"
                     /translation="MKSTPHIKPMNDVEIAETVLLPGDPLRAKFIAETYLDDVEQFNT
                     VRNMFGFTGTYKGKKVSVMGSGMGMPSIGIYSYELIHTFGCKKLIRVGSCGAMQENID
                     LYDVIIAQGASTDSNYVQQYQLPGHFAPIASYQLLEKAVETARDKGVRHHVGNVLSSD
                     IFYNADTTASERWMRMGILGVEMESAALYMNAIYAGVEALGVFTVSDHLIHETSTTPE
                     ERERAFTDMIEIALSLV"
     gene            967..2319
                     /gene="tet(38)"
                     /locus_tag="RFE25_002939"
     CDS             967..2319
                     /gene="tet(38)"
                     /locus_tag="RFE25_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(38)"
                     /protein_id="HDU2817906.1"
                     /translation="MNVEYSKIKKAVPILLFLFVFSLVIDNSFKLISVAIADDLNISV
                     TTVSWQATLAGLVIGIGAVVYASLSDAISIRTLFIYGVILIIIGSIIGYIFQHQFPLL
                     LVGRIIQTAGLAAAETLYVIYVAKYLSKEDQKTYLGLSTSSYSLSLVIGTLSGGFIST
                     YLHWTNMFLIALIVVFTLPFLFKLLPKENNTNKAHLDFVGLILVATIATTVMLFITNF
                     NWLYMIGALIAIIVFALYIKNAQRPLVNKSFFQNKRYASFLFIVFVMYAIQLGYIFTF
                     PFIMEQIYHLQLDTTSLLLVPGYIVAVIVGALSGKIGEYLNSKQAIITAIILIALSLI
                     LPAFAVGNHISIFVISMIFFAGSFALMYAPLLNEAIKTIDLNMTGVAIGFYNLIINVA
                     VSVGIAIAAALIDFKALNFPGNDALSSHFGIILIILGLMSIVGLVLFVILNRWTQSEK
                     "
BASE COUNT          798 a          361 c          438 g          863 t
ORIGIN      
        1 acgtagacaa cctccataaa gttacttaat cactctcatc atacaataat ttttactcga
       61 attggaaaaa ttataaaaat taaatataga taggctttga aaattagttt tatacaaggt
      121 tagtagctgt aactgtaaaa tgttcttaat attgtcaaaa tgtaatgctt gaaagcgctt
      181 ttaaaaaata ttattatata catgattaga caaatagaca aatcactata caaatattgg
      241 gaggaatatt ttatgaaatc aacaccacac attaaaccaa tgaatgacgt cgaaattgca
      301 gaaacggttc tattgccagg agatccgtta agagctaagt tcattgcaga aacttatttg
      361 gatgatgtgg aacagttcaa tacagtgcga aacatgtttg gttttaccgg aacatataaa
      421 ggtaaaaaag tttctgtcat gggttcaggt atgggtatgc catctattgg catttactct
      481 tatgaattaa ttcatacatt tggttgtaaa aaattaattc gcgttggctc ttgtggcgcg
      541 atgcaagaaa acattgattt atatgatgtg attattgcac aaggtgcctc tactgattca
      601 aattacgttc aacaatatca attaccaggt cattttgcgc caattgcttc ttatcaatta
      661 ttagaaaaag cagttgaaac agcacgtgac aaaggtgtac gtcatcatgt aggtaatgtg
      721 ttatcaagtg atattttcta taacgcggat acaacagcga gtgaacgttg gatgcgtatg
      781 ggtattttag gtgtagaaat ggaatcagct gcattataca tgaatgcaat ttacgctggt
      841 gtcgaagcat taggtgtgtt cacagtgagc gatcatttaa ttcatgaaac gtcaacaaca
      901 cctgaggaaa gggaacgtgc atttacagat atgattgaaa ttgcactgtc attggtgtag
      961 atgattatga atgttgaata ttctaaaata aagaaagcag tacctatttt attattctta
     1021 tttgtattca gtttggttat agacaactca tttaaattga tttctgtagc cattgctgat
     1081 gacttaaaca tatctgtaac gacagtaagt tggcaagcga cattagccgg tttagtaatt
     1141 ggtattggcg ctgtagtata cgcttcatta tctgatgcca ttagtatacg cacactattt
     1201 atttatggcg tgatattaat cattatcgga tcaattattg gttacatttt ccaacatcaa
     1261 ttcccattac ttttagttgg acgtattatt caaactgccg gtttagctgc tgcagagaca
     1321 ttatatgtga tatatgttgc aaagtatctt tctaaagagg accagaagac ttaccttggc
     1381 ttaagtacga gcagttattc cttgtcatta gttatcggta cattatcagg tggatttatt
     1441 tctacgtatt tacactggac aaatatgttt ttaattgcat taatcgtagt atttacgttg
     1501 ccattcctat ttaaattatt accaaaagaa aataatacga ataaagctca tttagatttt
     1561 gttggcttaa ttctagtggc aactattgct acaacagtca tgctgtttat tacgaacttt
     1621 aattggttat atatgattgg tgccttaatt gcgattatcg tttttgcgct atatattaaa
     1681 aatgcgcaac gtccattagt aaataaatca tttttccaaa ataaacgtta tgcttcattt
     1741 ttatttatag tatttgtaat gtatgctatc caattgggtt atatttttac gttcccattc
     1801 ataatggagc aaatttatca tctgcaacta gacacaacat cactgttatt agtaccgggt
     1861 tatatagtag cagtcattgt tggtgcatta agtggtaaaa tcggcgaata tctgaattca
     1921 aaacaagcga ttatcacagc aattatttta atagcactga gcttgatttt acctgcattt
     1981 gcagtaggta atcacatttc aatcttcgtc atttctatga tattctttgc aggtagcttt
     2041 gctttaatgt atgcaccttt acttaacgaa gccattaaaa caatagatct taatatgaca
     2101 ggtgtggcta ttggttttta taatttaatt attaatgtgg cggtatctgt aggtattgcg
     2161 attgctgcgg ctctaatcga ttttaaagca ttaaatttcc caggcaatga tgcattaagt
     2221 tcacatttcg gtattatttt aattatttta ggtttaatga gtattgtcgg attagtttta
     2281 ttcgtcatct taaatcgttg gacacaatct gaaaaataaa tagatataaa ttcgcgagat
     2341 atattcgtat ttatagtaaa attaaataaa gagattatat aacacgagga gtagtaagta
     2401 tgaaatttga gaaatatata gatcacactt tattgaagcc tgagtcaaca cgtacgcaaa
//
LOCUS       DAPDIM010000204         1793 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.152, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000204 DAPDIM010000000
VERSION     DAPDIM010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1793
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.152"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            136..1092
                     /locus_tag="RFE25_002940"
     CDS             136..1092
                     /locus_tag="RFE25_002940"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDU2817907.1"
                     /translation="MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLS
                     KGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYNGP
                     DMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKD
                     GNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQL
                     YQRSADIFLGVPFNIASYALLTHLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLA
                     RESFNPPTLKINSDKSIFDINYEDLEIVDYESHPAIKAPIAV"
     gene            1292..1771
                     /locus_tag="RFE25_002941"
     CDS             1292..1771
                     /locus_tag="RFE25_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDU2817908.1"
                     /translation="MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMG
                     RKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEM
                     IDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK"
BASE COUNT          653 a          275 c          308 g          557 t
ORIGIN      
        1 tctatttttc atataggagc tacttttggg tcagccccat tcctaaaatg agtgataaca
       61 aaatgctaca taaaattaag ttatatcaaa ctaaatatac atactataaa taatgaaaat
      121 gaggtgttat cgcatatgtt gaattcattt gatgcagcat atcacagtct ttgtgaagag
      181 gttttagaaa taggaaatac acgaaatgat cgcacaaata caggtacgat ttcgaaattt
      241 ggtcatcaac ttcgctttga cttatctaaa ggatttccac tattaacgac aaagaaagtt
      301 tcttttaaat tagtagcaac cgaattatta tggttcatta aaggagatac aaacatccaa
      361 tacttattaa aatataataa taatatttgg aacgaatggg cttttgaaaa ttatataaaa
      421 tcagacgagt ataacggtcc agatatgaca gatttcgggc atcgtgcatt gagtgatcct
      481 gaatttaacg aacaatataa agaacaaatg aaacaattta agcaacgtat tcttgaagat
      541 gatacttttg cgaagcaatt cggtgattta ggaaatgttt atggtaaaca atggcgagat
      601 tgggttgata aagatggtaa tcattttgat caacttaaaa cagtaattga acaaattaag
      661 cataatccag attcaagacg acacatcgta tctgcatgga atccaacaga aattgataca
      721 atggcacttc cgccttgtca taccatgttc cagttttatg tccaagatgg taagttaagt
      781 tgccagttat accaacgtag cgcagatatc tttttaggtg tgccatttaa tatcgcaagc
      841 tacgctttat tgacacacct tattgccaaa gaatgtggac ttgaagtagg agaatttgtg
      901 catacatttg gagatgcaca tatttattca aatcatattg atgcgattca aacacaatta
      961 gcacgtgaaa gcttcaatcc tccaacatta aaaattaaca gtgacaagtc tattttcgac
     1021 ataaattatg aagatttgga aattgttgac tatgaatcac atccagcaat aaaagctcca
     1081 atagcagtgt agtcattgca tagttagcta accatataga catcaaaatg acatcatagt
     1141 attttcaagt gcaaaaaagt acttttttgt gttaaacgtt ttcataaatt atgcaaaatc
     1201 attatttcta tcacacttta tgataaaaat tgtgttaaat taaagataac ttagtaataa
     1261 aaaatgaaat gatagaagaa ggaggataat tatgacttta tccattctag ttgcacatga
     1321 cttgcaacga gtaattggtt ttgaaaatca attaccttgg cacctaccaa atgatttgaa
     1381 acatgttaaa aaattatcaa caggtcatac tttagtaatg ggtcgtaaga catttgaatc
     1441 gattggtaaa ccactaccga atcgtcgaaa tgttgtactt acttcagata caagtttcaa
     1501 cgtagagggc gttgatgtaa ttcactctat tgaagatatt taccaactac cgggccatgt
     1561 tttcatattt ggagggcaaa cattatttga agaaatgatt gataaagtgg acgacatgta
     1621 tattactgtt attgaaggta aattccgtgg tgatacgttc tttccacctt atacatttga
     1681 agactgggaa gttgcctctt cagttgaagg taaactagat gagaaaaata caattccaca
     1741 tacctttcta catttaattc gtaaaaaata agggggaaaa cgaccatgac aaa
//
LOCUS       DAPDIM010000205         1310 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.157, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000205 DAPDIM010000000
VERSION     DAPDIM010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.157"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            23..388
                     /locus_tag="RFE25_002942"
     CDS             23..388
                     /locus_tag="RFE25_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDU2817909.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEKLGG
                     KNDYKDEIVYVYDYEKGDK"
     gene            389..>1310
                     /gene="aac(6')-Ie"
                     /locus_tag="RFE25_002943"
     CDS             389..>1310
                     /gene="aac(6')-Ie"
                     /locus_tag="RFE25_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HDU2817910.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLR"
BASE COUNT          540 a          106 c          219 g          445 t
ORIGIN      
        1 agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag gatttcttaa
       61 tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag gatttgcata
      121 ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact caataggaat
      181 gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta ttaaggaata
      241 ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta atcctagagc
      301 ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa tagtatatgt
      361 atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa tatgtataag
      421 aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg aaagagtatt
      481 agaattttat ggtggtagag ataaaaaata tacattagaa tcattaaaaa aacattatac
      541 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      601 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      661 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      721 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      781 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      841 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      901 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      961 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
     1021 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
     1081 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
     1141 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
     1201 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
     1261 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac
//
LOCUS       DAPDIM010000206         1180 bp    DNA     linear   BCT 31-AUG-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate H32156
            SAMEA114290723-rid19297093.guided.160, whole genome shotgun
            sequence.
ACCESSION   DAPDIM010000206 DAPDIM010000000
VERSION     DAPDIM010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114290723
            Sequence Read Archive: ERR11861200
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869468.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869468.1
            Genome Coverage       :: 116x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 14:58:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,945
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,797
            CDSs (with protein)               :: 2,797
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 43 of 81
            Pseudo Genes (incomplete)         :: 29 of 81
            Pseudo Genes (internal stop)      :: 26 of 81
            Pseudo Genes (multiple problems)  :: 16 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1180
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114290723-rid19297093.guided.160"
                     /isolate="H32156"
                     /isolation_source="Nose, throat inguinal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Switzerland"
                     /collection_date="2016-03-23"
     gene            1..157
                     /locus_tag="RFE25_002944"
                     /pseudo
     CDS             1..157
                     /locus_tag="RFE25_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            188..1063
                     /locus_tag="RFE25_002945"
                     /note="aph(2'')-Ia"
     CDS             188..1063
                     /locus_tag="RFE25_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HDU2817911.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     IENGRKEIYKRTYKD"
BASE COUNT          510 a           92 c          197 g          381 t
ORIGIN      
        1 agaaagaaat gctaatgcag ttattttaga ccctcataaa aataatccaa gagcaataag
       61 ggcataccaa aaatctggtt ttagaattat tgaagatttg ccagaacatg aattacacga
      121 gggcaaaaaa gaagattgtt atttaatgga atatagatat gatgataatg ccacaaatgt
      181 taaggcaatg aaatatttaa ttgagcatta ctttgataat ttcaaagtag atagtattga
      241 aataatcggt agtggttatg atagtgtggc atatttagtt aataatgaat acatttttaa
      301 aacaaaattt agtactaata agaaaaaagg ttatgcaaaa gaaaaagcaa tatataattt
      361 tttaaataca aatttagaaa ctaatgtaaa aattcctaat attgaatatt cgtatattag
      421 tgatgaatta tctatactag gttataaaga aattaaagga acttttttaa caccagaaat
      481 ttattctact atgtcagaag aagaacaaaa tttgttaaaa cgagatattg ccagtttttt
      541 aagacaaatg cacggtttag attatacaga tattagtgaa tgtactattg ataataaaca
      601 aaatgtatta gaagagtata tattgttgcg tgaaactatt tataatgatt taactgatat
      661 agaaaaagat tatatagaaa gttttatgga aagactaaat gcaacaacag tttttgaggg
      721 taaaaagtgt ttatgccata atgattttag ttgtaatcat ctattgttag atggcaataa
      781 tagattaact ggaataattg attttggaga ttctggaatt atagatgaat attgtgattt
      841 tatatactta cttgaagata gtgaagaaga aataggaaca aattttggag aagatatatt
      901 aagaatgtat ggaaatatag atattgagaa agcaaaagaa tatcaagata tagttgaaga
      961 atattatcct attgaaacta ttgtttatgg aattaaaaat attaaacagg aatttatcga
     1021 aaatggtaga aaagaaattt ataaaaggac ttataaagat tgattatata atatatgaaa
     1081 agctattata aaagacatta gtattaaata gtttaaaaaa atgaaaaata ataaaggaag
     1141 tgagtcaagt ccagactcct gtgtaaaatg ctatacaatg
//
